LOCUS       DAXMQE010000001       105053 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.001, whole genome shotgun sequence.
ACCESSION   DAXMQE010000001 DAXMQE010000000
VERSION     DAXMQE010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 105053)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 105053)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..105053
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.001"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            526..1053
                     /locus_tag="ACF4ZO_000001"
     CDS             526..1053
                     /locus_tag="ACF4ZO_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008962 - phosphatidylglycerophosphatase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HFD5485589.1"
                     /translation="MSIDDYRPTYMVEAIYDLRANDLLRHGITAVLVDLDNTLIAWNN
                     PDGTPEVRAWLDEMTIADISVVVVSNNKHSRVERAVSRFGVDFISRALKPFAYGIEKA
                     IARYGFDRNEVIMVGDQLMTDIRASHRAGIKSVLVKPLVASDAWNTKINRWREHRVMA
                     KLEEKYGKLSYQKGI"
     gene            1053..2171
                     /gene="yqeH"
                     /locus_tag="ACF4ZO_000002"
     CDS             1053..2171
                     /gene="yqeH"
                     /locus_tag="ACF4ZO_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HFD5485590.1"
                     /translation="MEELFCIGCGIQIQTEDKEKAGFTPAAALKKGMETGELYCQRCF
                     RLRHYNEITDVHITDDEFLRLLHEVGDSDALVVNVIDIFDFNGSIIPGLSRFISGNDV
                     LLVGNKKDILPKSVKDGKVTQWLAERAHEEGLRPLDVMLTSAQNKYAIKDLIERINEL
                     RNGRDVYVVGVTNVGKSTLINAIIQEITGNKDVITTSRFPGTTLDKIEIPLDDGTFIF
                     DTPGIIHRHQMAHYLSPKELKIVSPKKEIKPKTYQLNPEQTLFLGGLSRFDFINGERQ
                     GFTAFFDNQLELHRTKLAGANAFYDKHVGTLLTPPGKKELTAFPKLVRHEFTIDQKMD
                     IVFSGLGWIRVNGQKDSKAIVAAWAPEGVAVIVRKAII"
     gene            2197..2505
                     /gene="yhbY"
                     /locus_tag="ACF4ZO_000003"
     CDS             2197..2505
                     /gene="yhbY"
                     /locus_tag="ACF4ZO_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HFD5485591.1"
                     /translation="MLTSKQRAFLKSEAHSLKPIVQIGKNGLNDHIKTSIRQALDARE
                     LIKVTLLQNTDEDIHEVAEILEEEIGCDTVLKIGRILILYKVSAKKENRKLSPKVKAI
                     "
     gene            2574..3206
                     /locus_tag="ACF4ZO_000004"
     CDS             2574..3206
                     /locus_tag="ACF4ZO_000004"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HFD5485592.1"
                     /translation="MALELLTPFTKVELEEEKKESNRKQIGILGGNFNPIHNAHLVVA
                     DQVRQQLGLDQVLLMPECKPPHVDAKETIDEKHRLCMLELAIEDVEGLAIETCELERQ
                     GISYTYDTMLYLTEQHPDVDYYFIIGADMVDYLPKWHRIDELVKLVQFVGVQRPKYKA
                     GTSYPVIWVDLPLMDISSSMIRDFIKKGRQPNYLLPKRVLDYITQEGLYQ"
     gene            3203..3796
                     /gene="yqeK"
                     /locus_tag="ACF4ZO_000005"
     CDS             3203..3796
                     /gene="yqeK"
                     /locus_tag="ACF4ZO_000005"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HFD5485593.1"
                     /translation="MTYEDYLPYSRTELLAKIAEQMSPKRFKHVLGVEKAALSLAECY
                     GCNPDKAGLAALLHDYAKECPDQVFLDLIDKYQLSPELAKWNNNVWHGMVGIYKIQED
                     LGLKDKDILRAIEIHTVGAAEMTLLDKVLYVADYIEEGRIFPLVDDARKIAKLDLNQA
                     VAYETVNTVAYLASKAQPIFPQTLDTYNAFCSYLKEY"
     gene            3820..4173
                     /gene="rsfS"
                     /locus_tag="ACF4ZO_000006"
     CDS             3820..4173
                     /gene="rsfS"
                     /locus_tag="ACF4ZO_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0017148 - negative regulation of
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HFD5485594.1"
                     /translation="MKKEELLKIVVEATDEKRAKDILALDLEGLTSLTDYFVIASATN
                     SRQLEAIADNIREKVKEAGGDASHVEGNSQAGWVLLDLTDVVVHLFLEDERYHYNLEK
                     LWHEAPAVALDAYLA"
     gene            4221..4964
                     /locus_tag="ACF4ZO_000007"
     CDS             4221..4964
                     /locus_tag="ACF4ZO_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFD5485595.1"
                     /translation="MEHNYEKFASVYDAVMDDSLYDLWTDFSLRHLPKSKGRNRLLEL
                     ACGTGIQSVRFAQAGFDVTGLDLSQDMLAIAKKRAQSAKKKIDFIQGNMLDLSQVGQF
                     DFVTCYSDSICYMQDEVDVGDVFKEVYDVLANDGIFIFDVHSTYQTDECFPGYSYHEN
                     ADDFAMVWDTYADEAPHSVVHELTFFIQEDDGRFSRFDEVHEERTYELLTYDILLEQA
                     GFKSFKVYADFEDKEPTKTSKRWFFVAYK"
     gene            5218..6324
                     /locus_tag="ACF4ZO_000008"
     CDS             5218..6324
                     /locus_tag="ACF4ZO_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HFD5485596.1"
                     /translation="MTVTGIIAEFNPFHNGHKYLLETAEGLKIIAMSGNFMQRGEPAL
                     IDKWIRSEMALKNGADIVVELPFFVSVQSADYFAQGAIDILCQLGIQQLAFGTEDVID
                     YQKLIKVYEKKSKQMTAYLSTLEDTLSYPQKTQKMWEIFAGVKFSGQTPNHILGLSYA
                     KASAGKHIQLCPIKRQGAAYHSKDKNHLLASASAIRQHLNDWDFISHSVPNAGLLINN
                     PHMSWDHYFSFLKYQILNHSDLTSIFQVNDELASRIKKAIKVSQNIDHLVDTVATKRY
                     TKARVRRILTYILVNAKEPTLPKGIHILGFTSKGQAHLKKLKKSRPLITRIGAETWDE
                     MTQKADSIYQLGHQDIPEQSFGRIPIIIKNERLN"
     gene            6806..7522
                     /locus_tag="ACF4ZO_000009"
     CDS             6806..7522
                     /locus_tag="ACF4ZO_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019320144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFD5485597.1"
                     /translation="MGRKWANIVAKKTAKDGATSKVYAKFGVEIYVAAKQGEPDPELN
                     TALKFVIDRAKQAQVPKHVIDKAIDKAKGNTDETFVEGRYEGFGPNGSMIIVDTLTSN
                     VNRTAANVRTAYGKNGGNMGASGSVSYLFDKKGVIVFAGDDADSVFEQLLEADVDVDD
                     VEAEEGTITVYTAPTDLHKGIQALRDNGVEEFQVTELEMIPQSEVVLEGDDLETFEKL
                     IDALESDDDVQKVYHNVADL"
     gene            7725..8567
                     /locus_tag="ACF4ZO_000010"
     CDS             7725..8567
                     /locus_tag="ACF4ZO_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HFD5485598.1"
                     /translation="MIKKQYLGRATIALASTLVLAACGSSKKAESGNQGSSKEVLFAT
                     VGTTAPFSYEKGGQLTGYDIEVAKAVFKGSDDYKVSFKKTEWSSIFTGLDSGKYQMGG
                     NNISFTKERSAKYLFSYPIGSTPSVLVVPKDSDIKSFDDIQGHTTQVVQGTTSVAQLE
                     DFNKKHSDNPVTLKFTNENITQMLTNLSEGKADFKIFDAPTVNAIIKNQGLDNLKTIE
                     LTSTEQPFIYFIFSQDQEKLQSFVNKRIKELTADGTLSKLAKEHLGGDYVPSDKELKL
                     PTAN"
     gene            8895..9740
                     /locus_tag="ACF4ZO_000011"
     CDS             8895..9740
                     /locus_tag="ACF4ZO_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HFD5485599.1"
                     /translation="MSFKKWIGIVGIALASTVLVACSEKQDDKNTLTIGVMTKTESDQ
                     ARWDKVEELLKKDNITLKYKEFTDYSQPNKAVANGEVDINAFQHYNFLNNWNKENKEH
                     LVAIADTYISPINLFSGTSQDGKAKYKSVADLPNGAQIAVPNDATNESRALYVLQSAG
                     LIKLNVSGDQLATIANISENKKKLDIKELDASQTARALVSADAAVVNNSYAVPAKIDY
                     KTSLFKEKADDNSKQWINIIAGQKDWEKSEKADAIKKLIKAYQTDEVKKVVEKTSNGI
                     DVSVW"
     gene            9990..11054
                     /locus_tag="ACF4ZO_000012"
     CDS             9990..11054
                     /locus_tag="ACF4ZO_000012"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HFD5485600.1"
                     /translation="MNEAIIQLDHIDITFRQKKRVIEAVKDVTVHINQGDIYGIVGYS
                     GAGKSTLVRVINLLQAPTNGKITVDGDVTFDQGKIQLSANALRQKRRDIGMIFQHFNL
                     MAQKTAKENVAFALRHSSLSKTEKEHKVIELLELVGLSERADNYPAQLSGGQKQRVAI
                     ARALANDPKILISDEATSALDPKTTKQILALLQELNRKLGLTIVMITHEMQIVKDICN
                     RVAVMQNGVLIEEGSVLDIFSNPKEALTQKFITTATGIDEALEKINQQDIVKHLPANA
                     LLAQLKYAGTSTDEPLLNSIYRQFEVTANILYGNIEILDHIPVGDMIVVLEGQAENIL
                     AAEKALHEAGVDVSILKRGA"
     gene            11055..11747
                     /locus_tag="ACF4ZO_000013"
     CDS             11055..11747
                     /locus_tag="ACF4ZO_000013"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter permease"
                     /protein_id="HFD5485601.1"
                     /translation="MSQLIQTYLPNVYELGWSGDAGWGLAIWNTLYMTIVPFIVGGAI
                     GLLLGLLLVLTGPDGVIENKTICWVIDKVTSIFRAIPFVILIAILASFTYLLLRTTLG
                     ATAALVPLTFATFPFYARQVQVVFSELDKGVIEAAQASGATFWDIVKVYLSEGLPDLI
                     RVSTVTLISLVGETAMAGAIGAGGLGNVAISYGYNRFNNDVTWVATIIILLIIFVIQF
                     IGDSLTRRFSHK"
     gene            complement(11786..13177)
                     /gene="brnQ"
                     /locus_tag="ACF4ZO_000014"
     CDS             complement(11786..13177)
                     /gene="brnQ"
                     /locus_tag="ACF4ZO_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HFD5485602.1"
                     /translation="MKQKNVYIVIGFMLFALFFGAANLIYPAFLGIYSGHQILWSIIG
                     FCLTGVSLPLLGVIAVAKSGSGDVESLARPISKWYAIFYSSILYLSIGPFFAIPRTGA
                     TSFSVGIAPILGDNTTNKAIYAILFFGLSYFLAIKPSKLAENIGKFLTPTLLVVISIL
                     VIASFVHPAGNYGDAFNAGVGVNNAFKDFPFIAGLIQGYGTMDALASLVFAILVIEAT
                     KQFGAKTDKEVTKITLISGAIAILLLALVYIFVGRIGATSQSLFPFSDGSFTLHGNPV
                     NGGQILSHASRFYLGGIGQAFLAVVIFLACLTTSTGLITSSAEYFHKLVPALSHIAWA
                     TIFTLLSAFFYFGGLSVIINWSAPVLFLLYPLTVDLIFLVLAQKYFNNDPIVYRTTIG
                     LTFIPAIFDALLTLSQMTGLFNLPEPVTTFFQKTVPLGQFSIGWIIFAIIGFLLGFIL
                     SKTKKRRKANDII"
     gene            13411..14625
                     /gene="sstT"
                     /locus_tag="ACF4ZO_000015"
     CDS             13411..14625
                     /gene="sstT"
                     /locus_tag="ACF4ZO_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0015826 - threonine transport [Evidence
                     IEA];
                     GO_process: GO:0032329 - serine transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HFD5485603.1"
                     /translation="MKKIYDLWVRVSLIKKIGIGVVIGVMLGILAPDLTGFSILGKLF
                     VGGLKAIAPLLVFALVSQAISHQKKGRQTNMTLIIFLYLFGTFASALVAVLTAYLFPL
                     TLVLNTPVNTELSPPQGVAEVFQSLLLKLVDNPINALATANYIGVLSWAIIFGLALKA
                     ASQETKHLIKTAAEVTSQIVVWIINLAPIGIMSLVFTTISENGVGILSDYAFLILVLV
                     GTMVFVALVVNPLIAVLITRQNPYPLVLRCLRESGLTAFFTRSSAANIPVNMQLCQKI
                     GLSKDTYSVSIPLGATINMGGAAITINVLTLAAVHTFGIPIDFLTALLLSVVAAVSAC
                     GASGVAGGSLLLIPVACSLFGISNDLAMQVVGVGFIVGVIQDSCETALNSSTDVLFTA
                     IAENAFWKRKKA"
     gene            complement(14680..15354)
                     /gene="ktrA"
                     /locus_tag="ACF4ZO_000016"
     CDS             complement(14680..15354)
                     /gene="ktrA"
                     /locus_tag="ACF4ZO_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium uptake transporter gating subunit
                     KtrA"
                     /protein_id="HFD5485604.1"
                     /translation="MLKRKTVGVLGLGIFGRTVARELSNFDQDVIAIDIRESHVKEVA
                     DLVTKAAVGDITDKEFLLAVGIEHCDTVVIASGNNLESSVLAVMHCKKLGVPTIIAKA
                     KNKIFEEVLYGIGATKVITPERDSGKRVASNLLRRHIESIIYLEHGISMIEFVIPKSW
                     EGQSLSELDVRRKYKLNVIGMRQKEVKTLDTNVKPFEPLEPNTIIVAIANDHTFEKFD
                     YLGYLK"
     gene            complement(15364..16740)
                     /gene="ktrB"
                     /locus_tag="ACF4ZO_000017"
     CDS             complement(15364..16740)
                     /gene="ktrB"
                     /locus_tag="ACF4ZO_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium uptake transporter channel subunit
                     KtrB"
                     /protein_id="HFD5485605.1"
                     /translation="MKRSFIKSLSVTQRLTFSFAIVILIGTLLLSMPFTHYQNGPNTV
                     YLDHFFNVVSMVCVTGLSVVPVAEVYNGIGQTIAMALMQIGGLGLVTLIAVSTFALKR
                     KMRLSDQTLLQSALNRGDSKDLKHYLFFAYKVTFSLEAFAAIVIMIDFIPRFGWKNGI
                     FNSIFLAVSAFCNAGFDNLGSSSLKDFMLNPTLNVIITFLIISGGLGFAVWVDLGVAF
                     KKYFFERPHCYGATFRKLSNQSRLVLQTTAVILFLGTFLTWFLEKDNSKTIANFSLHQ
                     QLMVSFFQTVTMRTAGFATISYNDTLAPTNILYMIQMVIGGAPGGTAGGIKVTTAAIT
                     FLLFKAELSGQSEVTFRNRIIANKTIKQTMTVLIFFFAVLMIGFILLLSVEPHIAPIP
                     LLFESISAIATVGVSMDLTPQLSTAGRLIVIVLMFVGRVGPITVLISLIQRKEKTIQY
                     ATTDILVG"
     gene            complement(16825..17538)
                     /gene="rsmG"
                     /locus_tag="ACF4ZO_000018"
     CDS             complement(16825..17538)
                     /gene="rsmG"
                     /locus_tag="ACF4ZO_000018"
                     /EC_number="2.1.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005575 - cellular_component [Evidence
                     IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA];
                     GO_process: GO:0046118 - 7-methylguanosine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HFD5485606.1"
                     /translation="MTPQDFYRTLEEDGFSLSSKQKEQFDTYFKLLVEWNTKINLTAI
                     TEENEVYLKHFYDSIAPILQGFLANEPIKLLDIGAGAGFPSLPMKILFPNLEVTIIDS
                     LNKRISFLTLLAQELGLENVHFFHGRAEDFGQDKAFRGQFDAVTARAVARMQVLSELT
                     IPFLKIRGKLIALKAQAADQELEEAKNALCLLFGKVIKNHSYQLPNGDSRFITIVEKK
                     KETPNKYPRKAGLPNKKPL"
     gene            17688..18245
                     /locus_tag="ACF4ZO_000019"
     CDS             17688..18245
                     /locus_tag="ACF4ZO_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HFD5485607.1"
                     /translation="MPTVLIILVVLGVLALWLMISYNSLVKSRMHTKEAWSQIDVQLK
                     RRNDLIPNLIETVKGYASYEQKTFEKITDLRARVANASTPQETMAASNELSKQVTSLF
                     AVAENYPDLKANENFLKLQEELTNTENKISYSRQLYNSTTSNYNLQLESFPSNIAGKL
                     FGFKPSEFLQTPEAEKEVPKVEFNF"
     gene            18292..19188
                     /gene="htpX"
                     /locus_tag="ACF4ZO_000020"
     CDS             18292..19188
                     /gene="htpX"
                     /locus_tag="ACF4ZO_000020"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HFD5485608.1"
                     /translation="MLYQQISQNKQRTVVLLVVFFALLALIGASAGYLLLDNYAMGLV
                     LALVIGVIYATSMIFQSTSLVMSMNNAREVTEKEAPGFFHIVEDMAMVAQIPMPRVFI
                     IEDPSLNAFATGSSPQNAAVAATTGLLEVMNREELEGVIGHEISHIRNYDIRISTIAV
                     ALASAVTVISSIGGRMLWYGGGSRRQRDDGDDDVLRIITLLLSLLSLLLAPLVASLIQ
                     LAISRQREYLADASSVELTRNPQGMIKALEKLQLSQPMKHPVDDASAALYINEPRKKR
                     SFSSLFSTHPPIEERIERLKNM"
     gene            19422..19955
                     /locus_tag="ACF4ZO_000021"
     CDS             19422..19955
                     /locus_tag="ACF4ZO_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HFD5485609.1"
                     /translation="MLAISEIRKHPDGLSFDRLCDVKSMLLERDQQIIDIKAVKAVGN
                     VRYDKGLYLLDYQLSYEVILPSSRSMVPVCLSEVQHIQELFIEATDLADKKELVEDNL
                     VLVLDKDAINLEESIVDNILLAIPLQVLTEEEKKSKELPAGQNWAVLTEEDYQCLKEE
                     KQKENNPFASLQGLFDE"
     gene            20222..20908
                     /gene="covR"
                     /locus_tag="ACF4ZO_000022"
                     /gene_synonym="csrR"
     CDS             20222..20908
                     /gene="covR"
                     /locus_tag="ACF4ZO_000022"
                     /gene_synonym="csrR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CovR"
                     /protein_id="HFD5485610.1"
                     /translation="MTKKILIIEDEKNLARFVSLELQHEGYEVIVEVNGREGLETALE
                     KEFDLILLDLMLPEMDGFEVTRRLQTEKTTYIMMMTARDSIMDVVAGLDRGADDYIVK
                     PFAIEELLARIRAIFRRQDIESEKKVPSQGIYRDLVLNPQNRSVNRGDDEISLTKREY
                     DLLNILMTNMNRVMTREELLSNVWKYDEAVETNVVDVYIRYLRGKIDIPGKESYIQTV
                     RGMGYVIREK"
     gene            20914..22416
                     /gene="covS"
                     /locus_tag="ACF4ZO_000023"
                     /gene_synonym="csrS"
     CDS             20914..22416
                     /gene="covS"
                     /locus_tag="ACF4ZO_000023"
                     /gene_synonym="csrS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CovS"
                     /protein_id="HFD5485611.1"
                     /translation="MENQKQKQKKYKNSLPKRLSNIFFVLFFCIFSAFTLIAYSSTNY
                     FLLKKEKQSVFQAVNIVRVRLSEVDSNFTLENLAEVLYKNDKTHLRIDDRKGSRVIRS
                     ERDITNTLDANQDIYVYNIDKQMIFTTDNEESSPGLHGPIGRVYHDHIEDQYRGFSMT
                     QKVYSNRTGKFVGYVQVFHDLGNYYVIRARLLFWLLVVELFGTSLAYLIILITTRRFL
                     KPLHNLHEVIRNISENPNNLNLRSDISSGDEIEELSVIFDNMLDKLETYTKLQSRFIS
                     DVSHELRTPVAIIKGHIGLLQRWGKDDSDILEESLTATAHEADRMAIMINDMLDMIRV
                     QGSFEGHQNDMTVLEDSIETVVDNFRVLREDFIFTWQSENPKTIARIYKNHFEQALMI
                     LIDNAVKYSRKEKKIAINLSVTGKQEAIVRVQDKGEGISKEDIEHIFERFYRTDKSRN
                     RTSTQAGLGIGLSILKQIVDGYHLQMKVESELNEGSVFILHIPLAQSNES"
     gene            22631..23125
                     /gene="nrdR"
                     /locus_tag="ACF4ZO_000024"
     CDS             22631..23125
                     /gene="nrdR"
                     /locus_tag="ACF4ZO_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0140110 - transcription regulator activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator NrdR"
                     /protein_id="HFD5485612.1"
                     /translation="MRCPKCNYHKSSVVDSRQAEDGNTIRRRRECEQCHTRFTTFERV
                     EELPLLVIKKDGTREQFSRDKILNGVVQSAQKRPVSSTDIENVISRIEQKVRTTYENE
                     VSSTAIGNLVMDELAELDEITYVRFASVYKSFKDVDEIEELLQQITNRVRGKKKRLNN
                     DETN"
     gene            23109..24284
                     /locus_tag="ACF4ZO_000025"
     CDS             23109..24284
                     /locus_tag="ACF4ZO_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HFD5485613.1"
                     /translation="MMKPIDTFTYLKRNKVTLDSVTLIQLYFPIIGSDAVSIYQYFIH
                     FFDDGLQRHKFSDILNHLQFGMKRFEDALAILTAMELVSVYQLSDTYLITLHQPLSRD
                     LFFQHPAYSRLLEQKIGEVAVSELQVTVPSQARNISKRFSDIFGVQGDLTNVPQKPQK
                     NFDLSSFQQLMVRDGLQFEDNQKDIISLYSIAEQYDMTWFDTYQIAKTTAVNGKIRPE
                     RLLAKKNQSMTKPSKENFSQAEQIILREAKQDSALVFLEKIKKARRATITKDERILLQ
                     TLAKMNFLDDVINVMVLYTFNKTKSANLQKSYVLKMANDFAYQKVSTAEEAIVVLRAF
                     TDRQSRRQSKVKISQSNVPKWSNPDYQETTSQEEQAKLDQFKQAALKRLENLGKGGD"
     gene            24285..25187
                     /gene="dnaI"
                     /locus_tag="ACF4ZO_000026"
     CDS             24285..25187
                     /gene="dnaI"
                     /locus_tag="ACF4ZO_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HFD5485614.1"
                     /translation="MEKIGETMAKLGQNTRVNSDQLIQTILADPEVASFISQHHLSQE
                     QINLSLSKFNQFLVERQKYQLKDPSYIAKGYQPILAMNEGYADVSYLETKELVEAQKQ
                     AAISERIQLVSLPKSYRHIHLSDIDVNNASRMEAFSAILDFVEQYPSAEQKGLYLYGD
                     MGIGKSYLLAAMAHELSEKKGVSTTLLHFPSFAIDVKNAISNGSVKEEIDAVKNVPVL
                     ILDDIGAEQATSWVRDEVLQVILQYRMLEELPTFFTSNYSFADLERKWATIKGSDETW
                     QAKRVMERVRYLAREFHLEGANRR"
     gene            25250..26560
                     /gene="der"
                     /locus_tag="ACF4ZO_000027"
     CDS             25250..26560
                     /gene="der"
                     /locus_tag="ACF4ZO_000027"
                     /EC_number="3.6.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HFD5485615.1"
                     /translation="MVLPTVAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRQFSLIDTGGIDDVDAPFMEQIKHQAQIAMEEADVIVFVVSGKEGVTDADEY
                     VSKILYRTNTPVILAVNKVDNPEMRNDIYDFYSLGLGDPYPVSSVHGIGTGDVLDAIV
                     ENLPVEEAEENDDIIRFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DADGQEFTMIDTAGMRKSGKIYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTIDKDNHTVAKWEADIRDQFQFLTYAPIIFVSALTKQ
                     RLNKLPDLIKRISESQNKRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVSVKP
                     PTFVVFVNEEELMHFSYLRFLENQIRAAFTFEGTPIHLIARKRK"
     gene            26767..29865
                     /locus_tag="ACF4ZO_000028"
     CDS             26767..29865
                     /locus_tag="ACF4ZO_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SNF2 helicase associated domain-containing
                     protein"
                     /protein_id="HFD5485616.1"
                     /translation="MMARLIPGRVRNEGIKLYEQGLVSFQDDNKGILQIEVETYQVQY
                     GADDEDITCQCDTFHMKHYCKHIAAVEYFLKNDQKGKLFLKQLTNQTKIKETTKKMTS
                     FGSLFLDSLAMNEDDSVKYRLSALGSRSPFSSDYWWSLKINRLPDDRSYVIRDIKGFL
                     QLIKKEGFYQIGKNYFEQLSWLQFDPSSQDLIEFLWRLASDTDKGDNENIFPNHARHL
                     RLPSGFFEEGIHYLTSLYDFTFEGPSQTYHHLFVRSLEAEAGLYEFKVEVHRKSIELQ
                     IAEKNVQYLFDNDYLLYQDTFYHLTLKQRKMVQAIRSLPIEADLAKHIHFDLDDHAKL
                     AASLSDFKQIGLVEAPKSFAIRDFEVTFQFDLLNRDEISCQLMFDYGNYQVSDKASLE
                     ALPFASHLKKEEKINRSLLAFGFSPQFYSKKRLTSAKELYTFFEETVPCFERLGNVAL
                     STAIQALQVKEMPKIAIKRNQGLLDISFDFSTIIENDIDQAVTALFQNNPYFVSQTGQ
                     LVVFDDETQKVSKSLQELRARQLKNGHLQLDGIRALQVSKLFEGMTSVHFSKELEELA
                     YHLQHPETFSIKPLPVKAQMRDYQRNGVQWLSMLNHYGFGGILADDMGLGKTLQTLAF
                     LASHLKSDSKVLILSPSSLIYNWFDECQKFTPQLDVVVSYGLKQTRDQIIEEGHQITI
                     TSYSSFRQDFETYQAFHYDYLILDEAQVIKNAQTKISHCLRAFNTANCFALSGTPIEN
                     KMLEIWSIFQIVLPGLLPTKKEFLKLTAEQVSRYIKPFVMRRKKEDVLPELPDLIETN
                     YSNEMTDEQKAIYLAQLRQMQDQIRNSSDVDISRQKIEILSGITRLRQICDTPSLFMD
                     YQGESGKLDSLRILLTQIKENGHRALIFSQFRGMLDLAKQEMTALGLTSYQMTGSTPA
                     NERQEMTRAFNNGSKDAFLISLKAGGVGINLTGADTVILIDLWWNPAVEMQAISRAYR
                     IGQKENVEVYRLITRGTIEEKILELQESKRNLVTTVLDGNESRASMSIEEIKEILGLN
                     TH"
     gene            30107..30709
                     /locus_tag="ACF4ZO_000029"
     CDS             30107..30709
                     /locus_tag="ACF4ZO_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5485617.1"
                     /translation="MVKNQFPLVADGIAISDPAKQMALYENEDLITNIRGYYQDKEYD
                     DIARNEEFTAKATSRQAPSSKRFCSNDEKHHYVKEARQKAKQDLKEKRQAYLAKEMAY
                     VPKQVSKKQQPADSSPSQKQATTEMSRFTKKLHQDNYILAELPKEYKEPKNLPQQGTT
                     KKNNYDFLKSSQIYNNKEMRQQREKTIAQELNLSRFEDLP"
     gene            30749..32077
                     /gene="murC"
                     /locus_tag="ACF4ZO_000030"
     CDS             30749..32077
                     /gene="murC"
                     /locus_tag="ACF4ZO_000030"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008763 - UDP-N-acetylmuramate-L-alanine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HFD5485618.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHMVQGSDVEKYYFTQRGL
                     EQAGITILPFSEDNITPDMELIVGNAFRENNKEVAYALRHQIPFKRYHDFLGDFMKSF
                     ISFAVAGAHGKTSTTGLLSHVLKNITDTSYLIGDGTGRGSANAQYFVFESDEYERHFM
                     PYHPEYSIITNIDFDHPDYFTGIADVRNAFNDYAKQVKKALFVYGEDDELKKIEAPAP
                     IYYYGFEEGNDFIAYDITRTTNGSDFKVKHQGEVIGQFHVPAYGKHNILNATAVIANL
                     FVAGIDMALVADHLKTFSGVKRRFTEKIINDTIIIDDFAHHPTEIVATIDAARQKYPS
                     KEIVAIFQPHTFTRTIALLEDFACALNEADSVYLAQIYGSAREVDKGEVKVEDLAAKI
                     IKPSQVVTVENVSPLLDHDNAVYVFMGAGDIQLYEHSFEELLANLTKNNQ"
     gene            32123..32605
                     /locus_tag="ACF4ZO_000031"
     CDS             32123..32605
                     /locus_tag="ACF4ZO_000031"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFD5485619.1"
                     /translation="MLIRQVQGSDLEVIATIESDNFSPQEATTRAVLEERIRLIPDTF
                     LVALIDQEIVGYIEGPVVTTPILEDSLFHGVTKNPKTGGYIAITSLSIAKHFQQQGVG
                     TALLAALKDLVVAQQRTGLILTCHDYLISYYEMNGFINQGISESQHGGTLWYQMIWKL
                     "
     gene            32717..34291
                     /gene="mltG"
                     /locus_tag="ACF4ZO_000032"
     CDS             32717..34291
                     /gene="mltG"
                     /locus_tag="ACF4ZO_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008932 - lytic endotransglycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HFD5485620.1"
                     /translation="MALTDFKDKDQQDQQRSFKEQILAELEKANQIRKEKEEELFQKE
                     LEAKEAARRTAQLYAEYKRQDAFQKESIAHNNKTAKHFQAIKDAVMTSEAIKPTLLSE
                     KENSSLKTTSKRVVQANELQETASKESQVPLTIEKGHSVRRKLSKRQQTERAAKKIST
                     VLISSIIITLLAVTLAGAGYVYSALNPVDKNSDAFVQVEIPSGSGNKLIGQILQKKGL
                     IKNSTVFSFYTKFKNFTNFQSGYYNLQKSMSLEEIASALQEGGTAEPTKPSLGKILIP
                     EGYTIKQIAKAVEHNSKGKTKKAKTPFNEKDFLDLVTDEAFIQDMVKRYPKLLATIPT
                     KEKAIYRLEGYLFPATYNYYKETTMRELVEDMLAAMDATLVPYYDKIAASGKTVNEVL
                     TLASLVEKEGSTDDDRRQIASVFYNRLNSGMALQSNIAILYAMGKLGEKTTLAEDATI
                     DTTINSPYNIYTNTGLMPGPVASSGVSAIEATLNPASTDYLYFVANVHTGEVYYAKTF
                     EEHSANVEKYVNSQIQ"
     gene            34364..34846
                     /gene="greA"
                     /locus_tag="ACF4ZO_000033"
     CDS             34364..34846
                     /gene="greA"
                     /locus_tag="ACF4ZO_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016481121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HFD5485621.1"
                     /translation="MAEKTYPMTLTEKEQLEKELEELKLVRRPEIVERIKIARSYGDL
                     SENSEYDAAKDEQAFVEGQISTLETKIRYAEIIDSDAVAKDEVAIGKTVIVQEVGTTD
                     KDTYHIVGAAGADIFSGKISNESPIAQALIGKKTGDKVRIESPAATYDVEIISVEKTN
                     "
     gene            complement(35470..36393)
                     /gene="yidC"
                     /locus_tag="ACF4ZO_000034"
     CDS             complement(35470..36393)
                     /gene="yidC"
                     /locus_tag="ACF4ZO_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HFD5485622.1"
                     /translation="MKLTLNRILFSGLALSILFTLTGCVGRDAHGNPKGMIWEFLGKP
                     MSYFIDYFANNAGLGYGLAIIIVTIIVRTLILPLGLYQSWKASYQSEKMTFLKPVFEP
                     INKRIKQASSQEEKMAAQTELMAAQRAHGINPLGGIGCLPLLIQMPFFSAMYFAAQYT
                     KGVSTSTFMGIDLGSRSLVLTAIIAALYFFQSWLSMMAVSEEQREQMKTMMYTMPIMM
                     IFMSFSLPAGVGLYWLVGGFFSIIQQLITTYLLKPRLHKQIKEEYAKTPPKAYQSTSS
                     RKDVTPSQNMEQANLPKKIKSNRNAGKQRKR"
     gene            complement(36475..36753)
                     /locus_tag="ACF4ZO_000035"
     CDS             complement(36475..36753)
                     /locus_tag="ACF4ZO_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HFD5485623.1"
                     /translation="MQKVRLIVSGRVQGVGFRYATHTLALDIGDIYGRVWNNNDGTVE
                     ILAQSKDSDKIATFIQEVRKGPSKWAKVTYVDVTMANFEDFQDFQIGN"
     gene            37014..37751
                     /locus_tag="ACF4ZO_000036"
     CDS             37014..37751
                     /locus_tag="ACF4ZO_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrmH family RNA methyltransferase"
                     /protein_id="HFD5485624.1"
                     /translation="MVITSKANQLIKQTKKLLQKKHRKQSYLIEGWHLFEEAQKSGQV
                     FRHIFVLEEMVERLAGEQELVIVSPQVLKELTDSPSPQGIVAEVEIPKLAFPSDYKGK
                     YLVLEDVQDPGNLGTIIRTADAARFNGVFLSEKSADIYNQKTLRSMQGSHFHLPIWRT
                     DVYQLCRELQEYKTPILATTLSKKSVDYKSLTYHERLALVLGNEGQGISAEMVALADQ
                     LVHITMPGQAESLNVAVAAGILIFSLI"
     gene            37790..38290
                     /locus_tag="ACF4ZO_000037"
     CDS             37790..38290
                     /locus_tag="ACF4ZO_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HFD5485625.1"
                     /translation="MHYTEDKEYMEHVGHLIAHPRFQKLSHIVQHQHSTRLEHSINVS
                     YSSYKLAKRFGWDAKSTARGGLLHDFFYYDWRVTKFNKGHAWVHPRIAVRNAKKLTEL
                     NKKEEDIILKHMWGATIAFPRYKESYIVTMVDKYWAVKEAVTPLRQKWSNRRFLRRKT
                     LQSHNR"
     gene            38305..38994
                     /locus_tag="ACF4ZO_000038"
     CDS             38305..38994
                     /locus_tag="ACF4ZO_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HFD5485626.1"
                     /translation="MNDHVIYTQSDVGLNQFFAKIYSLVGMGVGLSAFVSYLMLYPFR
                     ENLISILVNQPMIYYGAAIIELILVFVASGAARKNTPAALPIFLIYSALNGFTLSFII
                     VAYAQTTVFQAFLSSAAVFFAMSIIGVKTKRDMSGLRKAMFAALIGVVVASLINLFIG
                     SGMMSYVISVISVLIFSGLIASDNQMIKRVYQATNGQVGDGWAVAMALSLYLDFINLF
                     ISLLRIFGRND"
     gene            39172..39414
                     /locus_tag="ACF4ZO_000039"
     CDS             39172..39414
                     /locus_tag="ACF4ZO_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HFD5485627.1"
                     /translation="MSTAIWILLLIVALGVGVFGGIFIARKQIEKEIGEHPRLTPEAI
                     REMMSQMGQKPSEAKIQQTYRNIIKQSKAAVSKGKK"
     gene            39592..40386
                     /gene="racE"
                     /locus_tag="ACF4ZO_000040"
     CDS             39592..40386
                     /gene="racE"
                     /locus_tag="ACF4ZO_000040"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008881 - glutamate racemase activity
                     [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HFD5485628.1"
                     /translation="MDTRPIGFLDSGVGGLTVVCELIRQLPHEKIVYIGDSARAPYGP
                     RPKKQIKEYTWELVNFLLTQNVKMIVFACNTATAVAWEEVKATLDIPVLGVVLPGASA
                     AIKSTTKGQVGVIGTPMTVASDIYRKKIQLLAPSVQVRSLACPKFVPIVESNEMCSSI
                     AKKIVYDSLSPLVGKIDTLVLGCTHYPLLRPIIQNVMGPSVKLIDSGAECVRDISVLL
                     NYFDINGNYHQKAVEHRFFTTANPEIFQEIASIWLKQKINVEHVTL"
     gene            40383..41369
                     /locus_tag="ACF4ZO_000041"
     CDS             40383..41369
                     /locus_tag="ACF4ZO_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047429 - nucleoside triphosphate
                     diphosphatase activity [Evidence IEA];
                     GO_process: GO:0009143 - nucleoside triphosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HFD5485629.1"
                     /translation="MSEKIYEYKDENNWFIGKMTGHNLISGWGVKHRTIKKIDDLLDG
                     IAATLDWENPKGYDVSVVRYQSPLSLITFIIDMINQETQREIKVIPHAGTILLMENAK
                     LLAVYLPEGGVSTATFFATSEQGFGDTILIATRNEGKTKEFRNLFGQLGYRVENLNDY
                     PELPEVAETGTTFEENARLKAETISHLTGKMVLADDSGLKVDALGDLPGVWSARFSGP
                     DATDAKNNAKLLHELAMVFDQKKRSAQFHTTLVVAAPNKDSLVVEAEWPGYIATQPKG
                     ENGFGYDPVFIVGETGRHAAELEADQKNQLSHRGQAVRKLMEVFPAWQAKQS"
     gene            41348..41869
                     /locus_tag="ACF4ZO_000042"
     CDS             41348..41869
                     /locus_tag="ACF4ZO_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFD5485630.1"
                     /translation="MASKTIIVMSDSHGDRDIVQAIKDKYLGQVDAIFHNGDSELNSS
                     DPIWAGIYVVGGNCDYDTGYPDRLVTQLGTVTIAQTHGHLYHINFTWDKLDYFAQEVA
                     ADICLYGHLHRPAAWQVGQILFMNPGSVTQPRGEINEKLYARVELTDTQIKVDYFTRD
                     HKLYPSLSKEFKR"
     gene            41866..42327
                     /gene="cbpB"
                     /locus_tag="ACF4ZO_000043"
     CDS             41866..42327
                     /gene="cbpB"
                     /locus_tag="ACF4ZO_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0180001 - cyclic-di-AMP binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP-binding protein CbpB"
                     /protein_id="HFD5485631.1"
                     /translation="MIAKEFETFLMSHLDNYLIPEQDLAIFIDTHNADHVMLLLVSNG
                     FSRVPVITREKKYVGTISISDIMMYQSKRQLTDWEMSQTDIGEMVNTKIETISITSSL
                     TEIMHKLIDFPFLPVVDRANRFVGIITRKSILKAVNSLLHDFTDDYTIIKK"
     gene            42324..43070
                     /gene="xerD"
                     /locus_tag="ACF4ZO_000044"
     CDS             42324..43070
                     /gene="xerD"
                     /locus_tag="ACF4ZO_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HFD5485632.1"
                     /translation="MKSYIEPFIASKALSQNSQKAYRYDLQQFCQLVGERVNQDKLLL
                     YQNSIANLSLSAKKRKLSTANQFLYYLYQIKYLNSYFRLTDTMKVMRTEKQQAAIINT
                     DIFYQKTPFVWGQLISLLILELGLTPSEVAGIEVANLDLSFQMLTLKTKKGVRVLPLS
                     QILIPFLEQQLVGKEVYLFEHRGIPFSRQWFFNHLKTFVRSIGYEGLTAQKLREQFIL
                     KEKLAGKSIIELSDILGLKSPVTLEKYYKS"
     gene            43070..43774
                     /locus_tag="ACF4ZO_000045"
     CDS             43070..43774
                     /locus_tag="ACF4ZO_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HFD5485633.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSQYKVDIYEVPIVEVIEQYLNYIET
                     LQVMKLEVAGDYMLMASQLMLIKSRRLLPKVVEHIEEEDLEQDLLEKIEEYSRFKAVS
                     QALAKQHDQRAKWYSKPKQELIFEDAILQEDKTVMDLFLAFSNIMAAKRAVLKNNHTV
                     IERDDYKIEDMMASIKQRLEKESVISLSAIFEECQTLNEVISIFLASLELIKLHVVFV
                     EQLSNFGAIILRKEKK"
     gene            43771..44322
                     /gene="scpB"
                     /locus_tag="ACF4ZO_000046"
     CDS             43771..44322
                     /gene="scpB"
                     /locus_tag="ACF4ZO_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HFD5485634.1"
                     /translation="MTYLSQIEALLFVAGEEGLSLRHLASMLSLTPTALQQQLEKLSQ
                     KYEKDQHSSLCLIETANTYRLVTKEGFAELLRAYAKTPMNQSLSRASLEVLSIVAYKQ
                     PITRIEIDDIRGVNSSGALSKLLAFDLIREAGKKDVVGRPHLYATTDYFLDYMGINHL
                     DELIEVSAVEPADEEIALFRTQD"
     gene            44443..45165
                     /locus_tag="ACF4ZO_000047"
     CDS             44443..45165
                     /locus_tag="ACF4ZO_000047"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HFD5485635.1"
                     /translation="MRINKYIAHAGIASRRKAEELIKQGLVTLNGQVITDLATTVKSG
                     DVVEIEGSPIYNEEKVYYLLNKPRGAISSVSDDKGRKTVLDLLPQVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDTMIHPRNEIDKVYLARVKGIATKENLRPLTRGIVIDGKKTKP
                     ARYNIVHVEADKNRSIVELTIHEGRNHQVKKMFESVGLLVDKLSRTRFGTVDLKGLRP
                     GEARRLNKKEISQLHNLANTKK"
     gene            45162..45425
                     /gene="yidD"
                     /locus_tag="ACF4ZO_000048"
     CDS             45162..45425
                     /gene="yidD"
                     /locus_tag="ACF4ZO_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HFD5485636.1"
                     /translation="MMKKLLIVSVKAYQKYISPLSPPSCRYKPTCSAYMLTAIEKHGT
                     KGILMGIARILRCHPFVAGGVDPVPEDFSLMRNKNTSKNAEKA"
     gene            45603..46151
                     /locus_tag="ACF4ZO_000049"
     CDS             45603..46151
                     /locus_tag="ACF4ZO_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HFD5485637.1"
                     /translation="MTTKELINKNDKVKKARNHIVLFQPQIPQNTGNIARTCAATNAP
                     LHIIKPMGFPIDDRKMKRAGLDYWDKLELHFYDHLEQFINQCHGQLHLISKFAVNNYS
                     QATYADGDSHYFLFGREDTGLPEDFMREHAEKALRIPMNDEHVRSLNVSNTVCMVIYE
                     ALRQQGFQGLELKHTYEHDKLK"
     regulatory      46260..46383
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            46462..47025
                     /locus_tag="ACF4ZO_000050"
     CDS             46462..47025
                     /locus_tag="ACF4ZO_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HFD5485638.1"
                     /translation="MSKTHKMIMIGILSAISFLLMLVSFAIIPGAAFLKIEFSIIPVL
                     FGLMIMDLKSAYLILLLRSLLKLFLNNRGVNDFIGLPMNIIAIALFVTAFALVWNRQK
                     TLSQYVFASLLGTGLLTFGMVVLNYTFAIPLYAIFANIDIRAYIGVTKYMMTMVIPFN
                     LVEGLIFAITFYFVYIASKPILERYLH"
     gene            47027..47680
                     /locus_tag="ACF4ZO_000051"
     CDS             47027..47680
                     /locus_tag="ACF4ZO_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HFD5485639.1"
                     /translation="MMTNKQTHFLIASFALLIFVIIGYTVKFFPERLALLDNTIQAEI
                     RGNLPIVLTQFFRGVTVFGNVMTQILLVIVSVLVLFFMKWKIEALFILSNGAIAAFLI
                     TTLKLFYQRPRPAIEHLVYAGGYSFPSGHAMGSMLIFGSLLIICYQRLHSKLLQFVTS
                     MIFIILILVIGLSRIYLGVHYPSDILAGFVLGFGILQFIYPFYKQKRFEWRFLLKQD"
     gene            47973..48893
                     /locus_tag="ACF4ZO_000052"
     CDS             47973..48893
                     /locus_tag="ACF4ZO_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407327.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HFD5485640.1"
                     /translation="MKKRYQTLNEHYRQLFGAKMFKVPIDAGFDCPNRDGTVAHGGCT
                     FCTVSGSGDAIVAPDAPIKEQFYKEIDFMHRKWPDVNRYLVYFQNFTNTHDTVDVIRD
                     RYEQAINEPGVVGINIGTRPDCLPDDTIAYLAELSERMHVTVELGLQTTYEETSRLIN
                     RAHSYDLYKETVRRLRHYPNINIVSHLINGLPKETHDMMLENVRRCVTDNDIQGIKLH
                     LLHLMTNTRMQRDYHEGRLKLLSQKDYVSIICDQLEIIPKHIVIHRITGDAPRDMLIG
                     PMWSLNKWEVLNAIDKEMERRGSFQGCKVD"
     gene            48932..49486
                     /locus_tag="ACF4ZO_000053"
     CDS             48932..49486
                     /locus_tag="ACF4ZO_000053"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFD5485641.1"
                     /translation="MLKRPIHLSHDFLAEVVDKSSVVVDATMGNGNDTAFLAQLAKKV
                     YAFDVQEQAIRKTSERLAQLGLLNAELILAGHEAVDQYVTEPVRAAIFNLGYLPSADK
                     SIITLPNTTLQALSKLLTLLMVGGRIAIMVYYGHDGGSLEKDALLDFVKQLDQRKVSA
                     MLYQPLNQVNTPPFLIMLEKLADV"
     gene            49619..50953
                     /locus_tag="ACF4ZO_000054"
     CDS             49619..50953
                     /locus_tag="ACF4ZO_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin family protein"
                     /protein_id="HFD5485642.1"
                     /translation="MEDPVSQPLVIQFLLLVVLTLLNAFFSASEMALVSLNRSRVEQK
                     AADGDKKYARLLRVLEEPNHFLSTIQVGITFISLLSGASLSASLGKVISGWLGNSATA
                     RTAGTIISLVFLTYVSIVLGELYPKRIAMNLKDKLAIVSAPIIIGLGRLVSPFVWLLS
                     ASTNLLSRLTPMTFDDADEQMTRDEIEYMLSKSEATLDAEEIEMLQGVFSLDEMMARE
                     VMVPRTDAFMIDINDDPLENIQEILKQSFSRIPVYDVDKDKIIGLIHTKRLLESGFRQ
                     GFDQINMRKMLQEPLFVPETIFVDDLLRQLRNTQNQMAILLDEYGGVAGLVTLEDLLE
                     EIVGEIDDETDKAEQFVHEIGDNTYIVVGTMTLNEFNDYFDTELESDDVDTIAGFYLT
                     GIGTIPSQDQKEAYEIDNKDKHLVLINDKVKDGRITKLKLILSNIEQIIEED"
     gene            51031..51822
                     /gene="pflA"
                     /locus_tag="ACF4ZO_000055"
     CDS             51031..51822
                     /gene="pflA"
                     /locus_tag="ACF4ZO_000055"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate-lyase-activating protein"
                     /protein_id="HFD5485643.1"
                     /translation="MTEKDYGQVTGMVHSTESFGSVDGPGIRFIIFLQGCKLRCQYCH
                     NPDTWEMETNNSKIRTVNDVLKEALQYKHFWGKKGGITVSGGEAMLQIDFITALFIEA
                     KKLGIHTTLDTCGFTYRPTPEYHQVLDNLLAVTDLILLDLKEIDEKQHKIVTRQPNKN
                     ILQFARYLSDKQIPVWIRHVLVPGLTDIDDHLTRLGEFVKTLKNVDKFEVLPYHTMGE
                     FKWRELGIPYQLKGVKPPTKERVQNAKNLMQTESYTEYMNRIHQS"
     gene            51953..52888
                     /locus_tag="ACF4ZO_000056"
     CDS             51953..52888
                     /locus_tag="ACF4ZO_000056"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004427 - inorganic diphosphate
                     phosphatase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HFD5485644.1"
                     /translation="MSKILVFGHQNPDTDAIASSYAFDYLSQKAFGLDTEVVALGTPN
                     EETAFALDYFGVEAPRVVESAKAQGSEQVILTDHNEFQQSIADIREVEVYGVVDHHRV
                     ANFETANPLYMRVEPVGSASSIVYRMFKENGIEVPKAIAGMLLSGLISDTLLLKSPTT
                     HVSDHLVAEELAELAEVNLEDYGMALLKAGTNLASKSEVELIGIDAKTFELNGNAVRV
                     AQVNTVDIAEVLERQEAIEAAIKDAMAAEGYSDFVLMITDIVNSNSEILAIGANMDKV
                     EAAFNFTLDNNHAFLAGAVSRKKQVVPQLTESFGA"
     gene            52964..53617
                     /locus_tag="ACF4ZO_000057"
     CDS             52964..53617
                     /locus_tag="ACF4ZO_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HFD5485645.1"
                     /translation="MITVFHSDKLTRQPFFQDLINYLDQHDHVILREIKKAFPNVTGI
                     DKAIESYVQAGYISRENKRYGINLPLVSSDQQLALDTMLFVDTCSAMYENILAVVFET
                     QLTNQTNHVMIKEKTNITRDDLTLANYFYRLKRGEKPSAEQMDLYDLLGDVNQEYALK
                     YMTTFLLKFTRKDLVMQKRPDIFVEALVTLGYLKQVEPTTYQLLMTLDKESLTFIAP"
     gene            complement(53662..54663)
                     /locus_tag="ACF4ZO_000058"
     CDS             complement(53662..54663)
                     /locus_tag="ACF4ZO_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecCD family ABC transporter permease"
                     /protein_id="HFD5485646.1"
                     /translation="MKSHRHLLGLYTSLILLLVSLMGLALSLGESHLSFLDLIHVFLG
                     KSSHAISFIVINIRLPRILAACLGGGSLALSGLLLQRLTRNPLADSGVLGITIGAGIS
                     LAIVVSFSFFEQAHISHYLPLFAMLGAIVTTFSVYWLSLTKQGQIDPTRLILTGVAVT
                     TMLSSLMVALVGHINRYKVDLVINWLSGQLIGDDWPTLSVIAPLLLCFWPLTYSQAHF
                     LNIMGLADNTAIGLGLPLNRKRRLILVLAAGLGALSVLLVGNISFIGLIAGHFSTYLV
                     GSNHKLTIPISILIGMILLLVADTVGRVYLVGSNIQTGILVSLIGAPYFLYLMAKTK"
     gene            complement(54660..55712)
                     /locus_tag="ACF4ZO_000059"
     CDS             complement(54660..55712)
                     /locus_tag="ACF4ZO_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecCD family ABC transporter permease"
                     /protein_id="HFD5485647.1"
                     /translation="MKTKHPFLCLERFCLKKTQIITKSHIFWLIFVLLSFSLCVAIYC
                     HLRFGAVALSHQDLNSILFGKQNGHKANVLLAIRLPRLFGATLTGSALAVSGTIMQAI
                     TRNPIAEPGLLGINAGAGLALVLAYAFVPHLHYSLIILLSLLGSSLAATLVFGLSYQS
                     GKGYHQLRLVLAGAMVSILLSALGQGITNYYHLANAVIGWQAGGLVGVNWQMIGYIAP
                     LIILSLCLAQLLSYHLTVLSLSESQAKALGQKTNLISAVFMILVLILSSAAVAIAGSI
                     SFIGLVIPHLMKHFTPHHYRYLLPLCAVSGASFMVWVDIACRNLNPPYETPLGALVSL
                     IGFPCFLWLIRRGGRY"
     gene            complement(55702..56634)
                     /locus_tag="ACF4ZO_000060"
     CDS             complement(55702..56634)
                     /locus_tag="ACF4ZO_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-hydroxamate ABC transporter
                     substrate-binding protein"
                     /protein_id="HFD5485648.1"
                     /translation="MKKLTLLLTLCLTTITLIACGNQATNHSNTASKSLSPMPQIAGV
                     TYYGDIPKQPKRVVSLASTYTGYLKKLDMNLVGVTSYDKKNPILAKTVKKAKQVAATD
                     LEAITTLKPDLIVVGSTEENIKQLAEIAPVISIEYRKHDYLQVLSDFGRIFNKEGKAK
                     KWLKDWKTKTAAYEKEVKAVTGDKATFTIMGLYEKDVYLFGKDWGRGGEVIHQAFHYD
                     APEKVKTEVFKQGYLSLSQEVLPDYIGDYVVVAAEDDKTGSALYESKLWQSIPAVKKH
                     HVIKVNANVFYFTDPLSLEYQLETLREAILSSEN"
     gene            complement(56660..57442)
                     /locus_tag="ACF4ZO_000061"
     CDS             complement(56660..57442)
                     /locus_tag="ACF4ZO_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD5485649.1"
                     /translation="MTTISAEDLTIAYEQRTIIDKLSFYIPEGKITTIIGANGCGKSS
                     LLKALTRLLPPKQGVVYLNGQNIATLETKEVAKKLALLPQVQEATNGITVYELVSYGR
                     FPHQSYFGNLSPADKKVIHWAMQATNVMAYADQPVDALSGGQRQRVWLAMALAQGTDT
                     IFLDEPTTYLDLNHQLEILELVKSLNKDAGKTIVMVLHDLNLSARYSDHLIAMKHGKI
                     HYTGTIADVMTSPIIQDIFQIKPVLVDDPIHNCPIVLTYQLQ"
     gene            complement(57688..59133)
                     /locus_tag="ACF4ZO_000062"
     CDS             complement(57688..59133)
                     /locus_tag="ACF4ZO_000062"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HFD5485650.1"
                     /translation="MITIEQLLDILKKDHNFREVLDADGYHYHYQGLSFERLSYDSRQ
                     VDGKTLFFAKGATFKADYLKEAITNGLQLYISEVDYELGIPVVLVTDIKKAMSLIAMA
                     FYGNPQEKLKLLAFTGTKGKTTAAYFAYHMLKESYKPAMFSTMNTTLDGKTFFKSQLT
                     TPESLDLFAMMAECVTNGMTHLIMEVSSQAYLVDRVYGLTFDVGVFLNISPDHIGPIE
                     HPTFEDYFYHKRLLMENSRAVVINSGMDHFSFLADQVADQEHMFYGPLSDNQITTSQA
                     FSFEAKGQLAGHYDIQLIGHFNQENAMAAGLACLRLGASLADIQKGIAKTRVPGRMEV
                     LTMTNHAKVFVDYAHNGDSLEKLLSVVEEHQTGKLMLILGAPGNKGESRRADFGRVIH
                     QHPNLTVILTADDPNFEDPEDISQEIASHIARPVEIISDREQAIQKAMSLCQGAKDAV
                     IIAGKGADAYQIVKGQQVAYAGDLAIAKHYL"
     gene            59221..60855
                     /locus_tag="ACF4ZO_000063"
     CDS             59221..60855
                     /locus_tag="ACF4ZO_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HFD5485651.1"
                     /translation="MSTEKKQLTQEELMVQGAAWSTAGNFISRLLGVLYIIPWYIWMG
                     QYAIQANALFNMGYNVYAYFLLISTTGLNVAIAKQVAKYNSMGQTEHSYQLIRSTLKL
                     MLGLGLIFSAIMYLGSPLFARLSGGDDTLVPIMHSLSLAVFIFPVMSVIRGIFQGHNN
                     IKPYAVSQIAEQLIRVIWMLLTTFFIMKLGSGDYASAVTQSTFAAFIGMVASMGVLGY
                     YLWKQGLLAAIFSKPDHTVSIDIKGLLLETLKESIPFIVTGSAIQAFQLIDQWTFVNT
                     MTLFTDYSRSQLLVLFGYFNANPAKITMVLIAVAASIGGVGIALLTENYVKKDMKAAA
                     RLIINNIEMLVMFLLPALTGAIILARPLYSVFYGASEERAIHLFVAVLFQTLLLALYT
                     LFSPMLQALFENRKAIYYFAYGILIKLVLQIPLIYLLHAYGPLLATTIALVVPIYLMY
                     RRLYQVTHFNRKLLQKRLLLTLIETLLMGLVVFVANWLLGYAFKPTGRLTSLLYLLII
                     GGLGMTVYTALTLLTHQLDKLIGSKASRLRQKLGWH"
     gene            61022..61651
                     /gene="upp"
                     /locus_tag="ACF4ZO_000064"
     CDS             61022..61651
                     /gene="upp"
                     /locus_tag="ACF4ZO_000064"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004845 - uracil phosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HFD5485652.1"
                     /translation="MGKCQVISHPLIQHKLSILRRQTTSTKDFRELVNEIAMLMGYEV
                     SRDLPLEDVDIQTPVSKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRNEETLEPVEYLVKLPEDINQRQIFLVDPMLATGGSAILAVDSLKKRGAANIKFVCL
                     VAAPEGVKKLQEAHPDIDIFTAALDDHLNEHGYIVPGLGDAGDRLFGTK"
     gene            61875..62465
                     /locus_tag="ACF4ZO_000065"
     CDS             61875..62465
                     /locus_tag="ACF4ZO_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002274529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004176 - ATP-dependent peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit"
                     /protein_id="HFD5485653.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDNTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGTKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRHRLEKILAQNAGK
                     TIKQIHKDAERDYWMSAEETLAYGFIDEIMENNELK"
     gene            62957..63232
                     /locus_tag="ACF4ZO_000066"
     CDS             62957..63232
                     /locus_tag="ACF4ZO_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HFD5485654.1"
                     /translation="MFQKQERIGLVVYLYYNRDARKLSKFGDLYYHSKRSRYLIIYIN
                     KNDLDTKLEEMRRLKCVKDIRPSAFDDIDRQFVGNLHRDETNNHQKG"
     gene            63481..64116
                     /gene="tmk"
                     /locus_tag="ACF4ZO_000067"
     CDS             63481..64116
                     /gene="tmk"
                     /locus_tag="ACF4ZO_000067"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004798 - thymidylate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006233 - dTDP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HFD5485655.1"
                     /translation="MITGKLITVEGPDGAGKTTVLEQLIPLLKQKVAQEILTTREPGG
                     VAISEYIRELILDINHTAMDPKTELLLYIAARRQHLVEKVLPALEAGQLVFIDRFIDS
                     SVAYQGAGRGLIKADIQWLNEFATDGLEPDLTLYFDVPSEIGLARINANQQREVNRLD
                     LETIEIHQRVRKGYLALAKEHPKRIVTIDATKPLKEVVSVALEHVLALLLA"
     gene            64134..65009
                     /locus_tag="ACF4ZO_000068"
     CDS             64134..65009
                     /locus_tag="ACF4ZO_000068"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HFD5485656.1"
                     /translation="MDLAQKAPNVYQAFQTILKKDRLNHAYLFSGDFANEEMALFLAK
                     VIFCEQKKDQTPCGHCRSCQLIEQGDFADVTVLEPTGQVIKTDVVKEMMANFSQTGYE
                     NKRQVFIIKDCDKMHVNAANSLLKYIEEPQGEAYIFLLTNDDNKVLPTIKSRTQVFQF
                     PKNEAYLYQLAQEKGLLNHQAKLVAKLATNTSHLERLLQTSKLLELITQAERFVSIWL
                     KDQLQAYLALNRLVQLATEKEEQDLVLTLLTLLLARERAQTPLTQLEAVYQARLMWQS
                     NVNFQNTLEYMVMSE"
     gene            65028..65267
                     /locus_tag="ACF4ZO_000069"
     CDS             65028..65267
                     /locus_tag="ACF4ZO_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tpl protein"
                     /protein_id="HFD5485657.1"
                     /translation="MGKRSLSKDLPVATKVAAHRGKKAFEENTALATDLMKEVSRLMI
                     QNQLEMTFINSVFPLDQHVVLIPFSAEEHMDFYNC"
     gene            65671..65994
                     /gene="yabA"
                     /locus_tag="ACF4ZO_000070"
     CDS             65671..65994
                     /gene="yabA"
                     /locus_tag="ACF4ZO_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HFD5485658.1"
                     /translation="MNKKELFDAFDGFSQNLMVTLAEIEAMKKQVQSLVEENTILRLE
                     NTKLRERLSHLEHETVAKNPSKQRKDHLEGIYDEGFHICNFFYGQRRENDEECMFCRE
                     LLDRK"
     gene            65999..66862
                     /gene="rsmI"
                     /locus_tag="ACF4ZO_000071"
     CDS             65999..66862
                     /gene="rsmI"
                     /locus_tag="ACF4ZO_000071"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0000451 - rRNA 2'-O-methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HFD5485659.1"
                     /translation="MQVQKSFKDKKTSGTLYLVPTPIGNLQDMTFRAVATLKEVDFIC
                     AEDTRNTGLLLKHFDIATKQISFHEHNSYEKIPDLIDLLISGRSLAQVSDAGMPSISD
                     PGHDLVKAAIDSDIAVVALPGASAGITALIASGLAPQPHVFYGFLPRKAGQQKAFFED
                     KHHYTETQMFCESPYRIKDTLTNMLACYGDRQVVLVRELTKLFEEYQRGSISEILSYL
                     EETPLKGECLLIVAGAQVDSEIELTADVDLVSLVQKEIQAGAKPNQAIKTIAKAYQVN
                     RQELYQQFHDL"
     gene            66889..67281
                     /locus_tag="ACF4ZO_000072"
     CDS             66889..67281
                     /locus_tag="ACF4ZO_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5684 domain-containing protein"
                     /protein_id="HFD5485660.1"
                     /translation="MTEDQATILILGVYGIILAVFSLSALLCLIANWRLFKRAGYKGW
                     HSLIPFYAGFVKHKITFGEDNKWFYFIGWVIAIYYYYVHFCYVRAFGGPKGLAVFGLF
                     FPGLASLIVAFGKTYTTQECHPVPHLLN"
     gene            complement(67328..67957)
                     /locus_tag="ACF4ZO_000073"
     CDS             complement(67328..67957)
                     /locus_tag="ACF4ZO_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005507 - copper ion binding [Evidence
                     IEA];
                     GO_process: GO:0055070 - copper ion homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HFD5485661.1"
                     /translation="MIKEFCAENLTLLPTLDAGQVSRVELCDNLAVGGTTPSYGVIKE
                     ACQLLHDKKISVATMIRPRGGDFVYNDLELKAMEEDILKAVEAGSDALVLGLLTTENQ
                     LDTDAIEQLLPATQGLPLVFHMAFDHIPTDHQHQALDQLIDYGFVRVLTHGSPEATPI
                     TDNVEQLKSLVTYANKRIEIMIGGGVTAENCQNLSQLTGTAIVHGTKII"
     gene            68256..68612
                     /locus_tag="ACF4ZO_000074"
     CDS             68256..68612
                     /locus_tag="ACF4ZO_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HFD5485662.1"
                     /translation="MITIYQYPKCSTCQRAMAELKQLVSDFEVIDIKANPPKAQDLKH
                     WMETSGYTIKNFFNTSGNSYRELGLKDKIDQLSLDKAAELLATDGMLIKRPILIKDGK
                     VLQVGYRKPYQELDLG"
     gene            complement(68686..69513)
                     /locus_tag="ACF4ZO_000075"
     CDS             complement(68686..69513)
                     /locus_tag="ACF4ZO_000075"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HFD5485663.1"
                     /translation="MKLISWNIDSLNAALTGESPRALLSRAVLDTLVAQDADIIAIQE
                     TKLSAKGPTKKHIEALLSYFPNYLHVWRSSVEPARKGYAGTMFLYKNTLNPVITFPEI
                     DAPTTMDAEGRIITLEFEDFFVTQVYTPNAGDGLRRLDDRQIWDHKYADYLTELDAQK
                     PVLATGDYNVAHKEIDLANPSSNRRSPGFTDEERQGFTNLLARGFTDTFRHLHGDIPH
                     VYTWWAQRSKTSKINNTGWRIDYWLASNRLVDKVKRSEMISSGERQDHTPILLDIDF"
     gene            69747..70928
                     /gene="lctO"
                     /locus_tag="ACF4ZO_000076"
     CDS             69747..70928
                     /gene="lctO"
                     /locus_tag="ACF4ZO_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HFD5485664.1"
                     /translation="MAQKTVITEETTDFVMDFKTSSAEGNVDFINVFDLEKMAQQVIP
                     KGAFGYIASGAGDTFTLHENIRSFNHKLIVPHSLKGVENPSTEITFDGDHLTSPLILA
                     PVAAHKLANEQGEVASAKGLKEFGSIYTTSSYSTTDLPEISAALGGTPHWFQFYYSKD
                     DGINRNIMDRVKAQGCKAIVLTADATVGGNREVDRRNGFVFPVGMPIVQEYLPDGAGK
                     TMDYVYKSAKQALTSKDIEYIATYSGLPVYVKGPQCAEDTLRALDAGASGIWVTNHGG
                     RQLDGGPAAFDSLQEVAEAVDHKVPIVFDSGIRRGQHIFKALASGADLVALGRPAIYG
                     LAMGGSIGTRQVFEKLNDELKMVMQLAGTQTIQDVKAFNLRHNPYDSSIPFDQNALRL
                     D"
     gene            71193..76139
                     /gene="scpC"
                     /locus_tag="ACF4ZO_000077"
     CDS             71193..76139
                     /gene="scpC"
                     /locus_tag="ACF4ZO_000077"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CXC chemokine-degrading serine protease SpyCEP"
                     /protein_id="HFD5485665.1"
                     /translation="MEKKQRFSLRKYKSGTFSVLIGSVFLMMMTTTVAADELTTTSEP
                     TITNHAQQQAQHLTNTELSSAESKPQDTSQITPKTNREKEQSQDLVSEPTTTELADTD
                     AASMANTGPDATQKSASLPPVNTDVHDWVKTKGAWDKGYKGQGKVVAVIDTGIDPAHQ
                     SMRISDVSTAKVKSKEDMLARQKAAGINYGSWINDKVVFAHNYVENSDNIKENQFEDF
                     DEDWENFEFDAEAEPKAIKKHKIYRPQSTQAPKETVIKTEETDGSHDIDWTQTDDDTK
                     YESHGMHVTGIVAGNSKEAAATGERFLGIAPEAQVMFMRVFANDVMGSAESLFIKAIE
                     DAVALGADVINLSLGTANGAQLSGSKPLMEAIEKAKKAGVSVVVAAGNERVYGSDHDD
                     PLATNPDYGLVGSPSTGRTPTSVAAINSKWVIQRLMTVKELENRADLNHGKAIYSESV
                     DFKNIKDSLGYDKSHQFAYVKESTDAGYNAQDVKGKIALIERDPNKTYDEMIALAKKH
                     GALGVLIFNNKPGQSNRSMRLTSNGMGIPSAFISHEFGKAMSQLNGNGTGSLEFDSVV
                     SKAPSQKGNEMNHFSNWGLTSDGYLKPDITAPGGDIYSTYNDNHYGSQTGTSMASPQI
                     AGASLLVKQYLEKTQPNLPKEKIADIVKNLLMSNAQIHVNPETKTTTSPRQQGAGLLN
                     IDGAVTSGLYVTGKDNYGSISLGNITDTMTFDVTVHNLSNKAKTLRYDTELLTDHVDP
                     QKGRFTLTSRSLKTYQGGEVTVPANGKVTVRVTMDVSQFTKELTKQMPNGYYLEGFVR
                     FRDSQDDQLNRVNIPFVGFKGQFENLAVAEESIYRLKSQGKTGFYFDESGPKDDIYVG
                     KHFTGLVTLGSETNVSTKTISDNGLHTLGTFKNADGKFILEKNAQGNPVLAISPNGDN
                     NQDFAAFKGVFLRKYQGLKASVYHASDKEHKNPLWVSPESFKGDKNFNSDIRFAKSTT
                     LLGTAFSGKSLTGAELPDGYYHYVVSYYPDVVGAKRQEMTFDMILDRQKPVLSQATFD
                     PETNRFKPEPLKDRGLAGVRKDSVFYLERKDNKPYTVTINDSYKYVSVEDNKTFVERQ
                     ADGSFILPLDKAKLGDFYYMVEDFAGNVAIAKLGDHLPQTLGKTPIKLKLTDGNYQTK
                     ETLKDNLEMTQSDTGLVTNQAQLAVVHRNQPQSQLTKMNQDFFISPNEDGNKDFVAFK
                     GLKNNVYNDLTVNVYAKDDHQKQTPIWSSQAGASASAIESTAWYGITARGSKVMPGDY
                     QYVVTYRDEHGKEHQKQYTISVNDKKPMITQGRFDTINGVDHFTPDKTKALGSSGIVR
                     EEVFYLAKKNGRKFDVTEGKDGITVSDNKVYIPKNPDGSYTISKRDGVTLSDYYYLVE
                     DRAGNVSFATLRDLKAVGKDKAVVNFGLDLPVPEDKQIVNFTYLVRDADGKPIENLEY
                     YNNSGNSLILPYGKYTVELLTYDTNAAKLESDKIVSFTLSADNNFQQITFKMTMLATS
                     QITAHFDHLLPEGSRVSLKTAQGQLIPLEQSLYVPKAYGKTVQEGTYEVVVSLPKGYR
                     IEGNTKVNTLPNEVHELSLRLVKVGDASDSTGDHKVMSKNNSQALTASATPTKTTTSA
                     TAKALPSAGEKMGLKLRIVGLVLLGLTCVFSRKKSTKD"
     gene            76911..77618
                     /locus_tag="ACF4ZO_000078"
     CDS             76911..77618
                     /locus_tag="ACF4ZO_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YoaK family protein"
                     /protein_id="HFD5485666.1"
                     /translation="MSKKKRKHYQVYEGLRCAMTLCFISGYVNAFTYMTQGKRFAGVQ
                     TGNLLSFAIRLSEQQLKEALQFLLPMIVFMLGQSFTYFMHRWATKKGLHWYLLSSVML
                     TGLAFGTALFTPFLPSNVTVAALAFFASIQVDTFKTLRGASYANVMMTGNIKNAAYLL
                     TKGLYEKNHELTHIGRNTLIVILAFAVGVVCSTLLCIAYGEYALMPILMPLLYVNYLL
                     AQEFYHIQTKIKPIKRT"
     gene            77858..79858
                     /gene="metG"
                     /locus_tag="ACF4ZO_000079"
     CDS             77858..79858
                     /gene="metG"
                     /locus_tag="ACF4ZO_000079"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004825 - methionine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006431 - methionyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HFD5485667.1"
                     /translation="MMKKPFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGHEV
                     FYLTGLDEHGQKIQTKAKEAGITPQTYVDNMAKDVKALWQLLDISYDTFIRTTDDYHE
                     EVVAAVFEKLLAQDDIYLGEYSGWYSVSDEEFFTESQLKEVFRDEDGQVIGGIAPSGH
                     EVEWVSEESYFLRLSKYADRLVAFFKERPDFIQPDGRMNEMVKNFIEPGLEDLAVSRT
                     TFTWGVPVPSDPKHVVYVWIDALLNYATALGYGQANHANFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDLPMPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERFGLDPLRY
                     YLMRSLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVAMINKYFDGTVPAYVDNGT
                     AFDADLSQLIDAQLADYHKHMEAVDYPRALEAVWTIIARTNKYIDETAPWVLAKEDGD
                     KAQLASVMAHLAASLRVVAHVIQPFMMETSAAIMAQLGLAPVSDLSTLALADFPANTK
                     VVAKGTPIFPRLDMEAEIDYIKAQMGDSSAISQEKEWVPEEVALKSEKDVITFETFDA
                     VEIRVAEVKEVSKVEGSEKLLRFRVDAGDGQDRQILSGIAKCYPNEQELVGKKLQIVA
                     NLKPRKMMKQYISQGMILSAEHGDQLTVLTVDPSVPNGSIIG"
     gene            80352..81365
                     /gene="nrdF"
                     /locus_tag="ACF4ZO_000080"
     CDS             80352..81365
                     /gene="nrdF"
                     /locus_tag="ACF4ZO_000080"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA];
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_process: GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HFD5485668.1"
                     /translation="MTQHYYERSQSPIEYALSETQKQLRSINWNYLNDDKDLEVWNRV
                     TQNFWLPEKVPVSNDLNSWRSLGEDWQQLITRTYTGLTLLDTVQATVGDVAQIQHSQT
                     DHEQVIYTNFAFMVGIHARSYGTIFSTLCSSEQIEEAHEWVVSTQSLQDRARVLIPYY
                     TGDDPLKSKVAAAMMPGFLLYGGFYLPFYLSARGKMPNTSDIIRLILRDKVIHNYYSG
                     YKYQQKVARLSPEKQAEMKAFVFDLLYELIDLEKAYLRELYAGFDLAEDAIRFSLYNA
                     GKFLQNLGYDSPFTDEETRVSPEVFAQLSARADENHDFFSGNGSSYVMGITEETTDDD
                     WEF"
     gene            81369..81857
                     /gene="nrdI"
                     /locus_tag="ACF4ZO_000081"
     CDS             81369..81857
                     /gene="nrdI"
                     /locus_tag="ACF4ZO_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_process: GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HFD5485669.1"
                     /translation="MAELIIVYFSSKSNNTHRFVQKLGLPAQRIPVDNRPLEVSTHYL
                     LIVPTYAAGGSDAKGAVPKQVIRFLNNPNNRKHCKGVISSGNTNFGDTFALAGPIISQ
                     KLQVPLLHQFELLGTATDVKKVQAIFARLKHHTHDKQKQTNNLITERTHPCHKPMRHT
                     SH"
     gene            81824..84004
                     /gene="nrdE"
                     /locus_tag="ACF4ZO_000082"
     CDS             81824..84004
                     /gene="nrdE"
                     /locus_tag="ACF4ZO_000082"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HFD5485670.1"
                     /translation="MSQTNASYLSLNALTRFKKPDGSYHFDSDKEAVRRYLEEHVSPN
                     QMAFNSLEDKLAYLINEGYYEQAIFDAYPNDLIKDAFHYAYQQGYRFLNLMGAMKFYQ
                     SYALKTLDGKQYLETFEDRAVMNALFLADGDQTFVFDVIDAILHRRFQPATPTFLNAG
                     KKRRGEYISCYLLRVEDNMESISRAISTSLQLSKRGGGVALCLTNLREIGAPIKGIEN
                     QATGIVPVMKLLEDSFSYANQLGQRQGAGAVYLHAHHPEVLTFLDTKRENADEKIRIK
                     SLALGLVIPDITFQLAKENKDMALFSPYDIKCAYGKDMSDISITEEYDKLLANPAIKK
                     TYISARKLFQLIAELHFESGYPYLLFDDTVNKRNPHAKKGRIVMSNLCSEIAQVSTPS
                     TFKEDLSFETIGEDICCNLGSINIAQAMADAPHFEQLITTSIRALDRVSRVSDLNCAP
                     SVEAGNAANHAVGLGVMNLHGFLATNHIYYDTKEAVDFTDLFFHAMAYHAFKASCQLA
                     KEKGAFAGFSLSTYADGTYFAKYLQEDAKPQTAKVATLLQDYGFTLPTVADWQALVAD
                     IKQFGLANAHLLAVAPTGSISYLSSCTPSLQPVVAPVEVRKEGSLGRIYVPAYQIDQA
                     NYAYYERGAYEVGPKAIIDVVAAAQKHVDQAISLTLFMTDQATTRDLNRSYIQAFKQN
                     CASIYYVRVRQDVLAGSEQYDEDSLVTAPGASDETTTECQSCMI"
     gene            complement(84211..84963)
                     /locus_tag="ACF4ZO_000083"
     CDS             complement(84211..84963)
                     /locus_tag="ACF4ZO_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosyltransferase"
                     /protein_id="HFD5485671.1"
                     /translation="MLKKRYQLAMILLLSCFSLIWQTEGLVELFVCEYYERAVCEGTP
                     AYFTFSDQKGAETLIKKRWGKGLVYPRTEQEAMAAYTCQQAALINTSLDKTKGELSQL
                     TPELRDQVAQLDAATHRLVIPWNIVVYRYVYETFLRDIGVSHADLTSYYRNDQFDPHI
                     LCKIKLGTRYTKHSFMSTTALKNGAMTHRPVEVRICVKKGAKAAFVEPYSAVPSEVEL
                     LFPRGCQLEVVGAYVSQDHKKLHIEAYFKGSL"
     gene            85420..85860
                     /locus_tag="ACF4ZO_000084"
     CDS             85420..85860
                     /locus_tag="ACF4ZO_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5485672.1"
                     /translation="MKTKSKRFLNLATLCLALLGTTLLMGRPVKAEVVSRDNSTEQTD
                     IMKRRYMDSTGISEKELEQKYGEDRFQGYLDGYKEGLEKSDIPKWSDIKVPDGRDDDY
                     RDGYEQGFLEGRREARPIASFFEAVWQVLTDIFGGWFSSNDSPQ"
     gene            86048..86299
                     /locus_tag="ACF4ZO_000085"
     CDS             86048..86299
                     /locus_tag="ACF4ZO_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5485673.1"
                     /translation="MPEKKVLPVLSMVVSFVCLLDHIFFFATYSYLYLPLVASSLALI
                     GLVQNKGRQKVWSLAGLILAALAVAVVAYAYYDPTVIPY"
     gene            complement(86948..87124)
                     /locus_tag="ACF4ZO_000086"
     CDS             complement(86948..87124)
                     /locus_tag="ACF4ZO_000086"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5485674.1"
                     /translation="MKKTLTLLLALFAIGVTSSVRAEDAIKWELDPDTSPAIRVTVSP
                     ENGTNKLQFTLPRG"
     gene            87219..87353
                     /locus_tag="ACF4ZO_000087"
     CDS             87219..87353
                     /locus_tag="ACF4ZO_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5485675.1"
                     /translation="MARLFLVGADRFFPSQLLAVAILPLQSVWASGRVLRLPILLVAF
                     "
     gene            87485..87721
                     /locus_tag="ACF4ZO_000088"
     CDS             87485..87721
                     /locus_tag="ACF4ZO_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018367459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HFD5485676.1"
                     /translation="MTFEEILPGLKAKKKYVRTGWGGAENYVQLFDTLEVDGKVLQAT
                     PYFLIHVTGAGEGFSMWAPTPCDVLAEDWIEVND"
     gene            87714..88412
                     /locus_tag="ACF4ZO_000089"
     CDS             87714..88412
                     /locus_tag="ACF4ZO_000089"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HFD5485677.1"
                     /translation="MTKVVLVTGCASGIGYAQARYFLRQGYHVYGVDKSDKPDLNGNF
                     HFIKLDLSSELSPLFKVVPSVDILCNTAGILDAYKPLLDVSDEEVEHLFDINFFATVK
                     LTRHYLRRMVEKQSGVIINMCSIASFIAGGGGVAYTSSKHALAGFTRQLALDYAKDQI
                     HIFGIAPGAVKTAMTASDFEPGGLADWVARETPIGRWTEPDEVAELTGFLASGKARSM
                     QGEIVKIDGGWTLK"
     gene            88488..89447
                     /locus_tag="ACF4ZO_000090"
     CDS             88488..89447
                     /locus_tag="ACF4ZO_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFD5485678.1"
                     /translation="MKLAVLGTGMIVKEVLPVLQKIDGIDLVAILSTVRSLTTAKDLA
                     KAYHMPLATSKYEAVLGNEEIDTVYIGLPNHLHFAYAKKALLAGKHVICEKPFTMTAG
                     ELDELVIIAKKRKLILLEAITNQYLSNMTFIKEHLDQLGDIKIVECNYSQYSSRYDAF
                     KRGDIAPAFNPKMGGGALRDLNIYNIHFVVGLFGRPKTVQYLANMDKGIDTSGMLVMD
                     YEQFKVVCIGAKDCTAEIKSTIQGNKGSLAVLGATNTLPQVQLSLHGHEPQVINHNKH
                     GHRMYEEFVAFRDMIDQRDFEKVNQALEHSRAVMSVLERAVHS"
     gene            89780..91117
                     /locus_tag="ACF4ZO_000091"
     CDS             89780..91117
                     /locus_tag="ACF4ZO_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFD5485679.1"
                     /translation="MEEDYNKREPEKFTQFLRRQKVVFFVAFFGYVCAYLVRNNFKLM
                     SNTIMVQNGWDKAQIATLLSCLTVSYGLAKFYMGALGDRVSLRKLFSISLGASALICI
                     LIGFFNSSMVVLGILLVLCGVVQGALAPASQAMIANYFPNKTRGGAIAGWNISQNMGS
                     ALLPLTIALLTSMGLVVPANGNILLAFLIPGVLVFLFALCCWKLGGDNPESEGLDSLR
                     TMYGDAGESAVASEEEKYNLSYWQLIWKYVFCNPSLLLVAAVNVALYFVRFGIEDWMP
                     IYLSQVANMSEAHIHFAISILEWVAIPGSLVFAWLAVRYPNKMAKIGAIGLFVLAAIV
                     FVYERLTATGAPNYFLLLVIAGILGSLIYGPQLIVNILTINFVPLNVAGTAIGFVGVT
                     AYLIGNMGANWLMPILADGFGWFWSYIVVAALSAFSAVGYLILAKREEEIIKD"
     gene            91291..92673
                     /gene="glmU"
                     /locus_tag="ACF4ZO_000092"
     CDS             91291..92673
                     /gene="glmU"
                     /locus_tag="ACF4ZO_000092"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003977 - UDP-N-acetylglucosamine
                     diphosphorylase activity [Evidence IEA];
                     GO_function: GO:0019134 - glucosamine-1-phosphate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0006048 - UDP-N-acetylglucosamine
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HFD5485680.1"
                     /translation="MTNYAIILAAGKGTRMTSDLPKVLHKVSGLTMLEHVFRSVKAIS
                     PEKAVTVIGHKSEMVRAVLADQSAFVHQTEQLGTGHAVMMAETQLEGLEGHTLVIAGD
                     TPLITGESLKSLIDFHVNHKNVATILTATAQDPFGYGRIVRNKDGEVIKIVEQKDANE
                     YEQQLKEINTGTYVFDNKRLFEALKCITTNNAQGEYYLTDVVAIFRANKEKVGAYILR
                     DFNESLGVNDRVALATAETVMRQRITQKHMVNGVTFQNPETVYIESDVTIAPDVLIEG
                     NVTLKGRTHIGSGTVLTNGTYIVDSEIGDNCVVTNSMIESSVLAAGVTVGPYAHLRPG
                     TTLDREVHIGNFVEVKGSHIGEKTKAGHLTYIGNAQVGSSVNVGAGTITVNYDGQNKY
                     ETVIGDHAFIGSNSTLIAPLEIGDHALTAAGSTISKTVPIDSIAIGRSRQVTKEGYAK
                     RLAHHPSRSK"
     gene            92704..93258
                     /locus_tag="ACF4ZO_000093"
     CDS             92704..93258
                     /locus_tag="ACF4ZO_000093"
                     /EC_number="3.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HFD5485681.1"
                     /translation="MKFEEKTLKRQTVFDGHIFKVVVDDVELPNNLGQSKRELIFHRG
                     AVAVLAITPERKILLVKQYRKAIERVSYEIPAGKLEIGEEGSKLKAAARELEEETAYT
                     GTLTFLYEFYTAIGFCNEKITLFLATDLTQVANPKPQDDDEVIEVLELTYQECMDLVA
                     QGKLADAKTLIALQYYALHFGGEQ"
     gene            93258..93509
                     /gene="macP"
                     /locus_tag="ACF4ZO_000094"
     CDS             93258..93509
                     /gene="macP"
                     /locus_tag="ACF4ZO_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall synthase accessory phosphoprotein
                     MacP"
                     /protein_id="HFD5485682.1"
                     /translation="MGRPLLTDDIIEKARRMETFEPDDAVDFDTKVMTLPEKDEKARI
                     YKSRRIENAKRSQLQSKLNVILIAVMLLIAILVYAIFYL"
     gene            93529..94224
                     /locus_tag="ACF4ZO_000095"
     CDS             93529..94224
                     /locus_tag="ACF4ZO_000095"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008782 - adenosylhomocysteine
                     nucleosidase activity [Evidence IEA];
                     GO_function: GO:0008930 - methylthioadenosine nucleosidase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009164 - nucleoside catabolic process
                     [Evidence IEA];
                     GO_process: GO:0019509 - L-methionine salvage from
                     methylthioadenosine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HFD5485683.1"
                     /translation="MKIGIIAAMEEELSLLLANLLDAQEHQVLSKTYYTGRFGKHELI
                     LVQSGVGKVMSAMTVAILVEHFKAQAIINTGSAGAVASHLAIGDVVVADRLVYHDVDA
                     TAFGYAYGQMAGQPLYYDCDPQFVAIFKQVLKHEKTNGQVGLIATGDSFVAGQDKIDP
                     IKTAFSDVLAVEMEGAAIAQAAHTAGKPFIVVRAMSDTAAHDANITFDQFIIEAGKRS
                     AQTLMTFLENLPV"
     gene            94375..94716
                     /locus_tag="ACF4ZO_000096"
     CDS             94375..94716
                     /locus_tag="ACF4ZO_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5485684.1"
                     /translation="MTLKKHYYLLSLLALVTFGAAFNTSQSVSAQVYSNGGYRQGLTD
                     EKSHLQYSKDNAQLQLRNILNGYQDDLGKHYSSYYYYNLRTVMGLSSKQKIEEHYEKL
                     KNKLHDMYNHY"
     gene            complement(94815..95462)
                     /locus_tag="ACF4ZO_000097"
     CDS             complement(94815..95462)
                     /locus_tag="ACF4ZO_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HFD5485685.1"
                     /translation="MTPNKEDYLKCIYEIGEQETKITNKMVAEKMHVSAPAVSEMIKK
                     MISQGWIVKDKAKGYLLKDKGYALVANLYRKHRLIEVFLIHQLGYNTQEVHQEAEVLE
                     HTVSDTFIDRLDKILDFPDFCPHGGTIPRYGQPLVEMNTTTLNTITELGRFRLSRIHD
                     HFDLIQYLETHHLNINTELTLTQIDTFAKTYTICYGDKELVIPENIAKQLYVTAL"
     gene            95608..96540
                     /locus_tag="ACF4ZO_000098"
     CDS             95608..96540
                     /locus_tag="ACF4ZO_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein"
                     /protein_id="HFD5485686.1"
                     /translation="MGKKMSLILGAFLSVFLLVACSSTGTKTAKSDKLKVVATNSIIA
                     DMTKAIAGDKIDLHSIVPIGQDPHEYEPLPEDVEKTSNADVIFYNGINLEDGGQAWFT
                     KLVKNAQKTKNKDYFAVSDGIDVIYLEGASEKGKEDPHAWLNLENGIIYSKNIAKQLI
                     AKDPKNKETYEKNLKAYVAKLEKLDKEAKSKFDAIAENKKLIVTSEGCFKYFSKAYGV
                     PSAYIWEINTEEEGTPDQISSLIEKLKVIKPSALFVESSVDRRPMETVSKDSGIPIYS
                     EIFTDSIAKKGKPGDSYYAMMKWNLDKISEGLAK"
     gene            96604..97329
                     /locus_tag="ACF4ZO_000099"
     CDS             96604..97329
                     /locus_tag="ACF4ZO_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004218966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HFD5485687.1"
                     /translation="MITTNNLCVTYDGNSNALEAINVTIDGPSIVGIIGPNGAGKSTF
                     MKAILNLIDYQGHVTVDGKDGRKLGHTVAYVEQRSMIDYNFPITVKECVALGTYSKLG
                     LFRRVGKKQFEQVDKVLKQVGLEDFGHRPIKSLSGGQFQRMLVARCLIQESDYIFLDE
                     PFVGIDSVSEKIIVDLLKELKMAGKTILIVHHDLSKVEHYFDKLMILNKHLVAYGNVC
                     EVFTVDTLSKAYGNHLILGKEMV"
     gene            97330..98184
                     /locus_tag="ACF4ZO_000100"
     CDS             97330..98184
                     /locus_tag="ACF4ZO_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease subunit"
                     /protein_id="HFD5485688.1"
                     /translation="MSMKFFEGLMSYHFLQNALITAVVIGIVSGAVGCFIILRSMSLM
                     GDAISHAVLPGVALSFILGVNFFIGAIVFGLLASVIITYIKENSVIKGDTAIGITFSS
                     FLALGVILIGVANSSTDLFHILFGNILAVQDSDKWITIGVSIFVLVVISLFFKELLLT
                     SFDPILAKSMGVKVNAYHYLLMVLLTLVAVTAMQSVGTILIVALLITPAATAYLYANS
                     LKVMLVMSSLLGALASVLGLYLGYTFNVAAGSSIVLTSAMMFLISFFVSPKQGYLKRW
                     MQKKEKTP"
     gene            complement(98330..99136)
                     /locus_tag="ACF4ZO_000101"
     CDS             complement(98330..99136)
                     /locus_tag="ACF4ZO_000101"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFD5485689.1"
                     /translation="MKKLLSLSLVAISLLSLSACESVDRAIKGDKYIDEKTAKEESEA
                     ASKAYEESIQKALKADASQFPQLTKEVGKEEAKVVMRTSQGDITLKLFPKYAPLAVEN
                     FLTHAKKGYYDNLTFHRVINDFMIQSGDPKGDGTGGESIWKGKDPKKDAGNGFVNEIS
                     PFLYHIRGALAMANAGANTNGSQFYINQNKKNQSKGLSSTNYPKPIISAYEHGGNPSL
                     DGGYTVFGQVIDGMDVVDKIAATSINQNDKPKQDITITSIDIVKDYRFKN"
     gene            99353..101758
                     /locus_tag="ACF4ZO_000102"
     CDS             99353..101758
                     /locus_tag="ACF4ZO_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015616 - DNA translocase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HFD5485690.1"
                     /translation="MVKRNQRKKSAPKKRLTKAEVEKQRAIKRMILSVLMALLLIFAM
                     LRLGVFGVTTYNMIRFLVGSLAYPFMFAWLIYLFCFKWLRQKDGMIAGVVIAFLGLLV
                     EWHAFLFAMPRMLDQDIFLGTARLITRDLLALRVTEFVGGGMLGALLYKPIAFLFSNI
                     GSYFIGFLFILLGLFLMTPWDIYDVSHFVKEAVDKLAVAYQENKEKRFIKREEHRLQA
                     EKEALEKQAQEEEKRLAELTVDPETGEIVEDSQSQVSYDLAEDMTKEPEILAYDSHLK
                     DDEASLFDQEDLAYAHEEIGAYDSLSALASSEDEMDMDEPVEVDFTPKTHLLYKLPTI
                     DLFAPDKPKNQSKEKNLVRKNIKVLEDTFQSFGIDVKVERAEIGPSVTKYEIKPAVGV
                     RVNRISNLADDLALALAAKDVRIEAPIPGKSLIGIEVPNSEIATVSFRELWEQSDANP
                     ENLLEVPLGKAVNGNARSFNLARMPHLLVAGSTGSGKSVAVNGIISSILMKARPDQVK
                     FMMIDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFSKIGVRNIA
                     GYNTKVEEFNASSEQKQIPLTLIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGIH
                     MILATQRPSVDVISGLIKANVPSRMAFAVSSGTDSRTILDENGAEKLLGRGDMLFKPI
                     DENHPVRLQGSFISDDDVERIVNFIKDQAEADYDDAFDPGEVSDNDPGFSGNGGAAEG
                     DPLFEEAKALVLETQKASASMIQRRLSVGFNRATRLMDELEEAGVIGPAEGTKPRKVL
                     QTN"
     gene            complement(101828..102181)
                     /locus_tag="ACF4ZO_000103"
     CDS             complement(101828..102181)
                     /locus_tag="ACF4ZO_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HFD5485691.1"
                     /translation="MMIYKLTALAFLIVTPLFAMIVTSLFKLNKKGFKFPDVALLLFA
                     IEIVLVSGKFFIHNLLPYYLIIMSLLAIVISLLLVIRTQSFSYHRFMKLFWRVGFLVT
                     VIFYLILVIFIFTLA"
     gene            102403..103393
                     /locus_tag="ACF4ZO_000104"
                     /pseudo
     CDS             102403..103393
                     /locus_tag="ACF4ZO_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564846.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISAs1 family transposase"
     gene            103607..104032
                     /gene="rplK"
                     /locus_tag="ACF4ZO_000105"
     CDS             103607..104032
                     /gene="rplK"
                     /locus_tag="ACF4ZO_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HFD5485692.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFDFITKTPPAAVLLKKAAGVEKGSGTPNTTKVATVTR
                     AQVQEIAETKMPDLNAANIEAAMRMIEGTARSMGFTVTD"
     gene            104138..104827
                     /gene="rplA"
                     /locus_tag="ACF4ZO_000106"
     CDS             104138..104827
                     /gene="rplA"
                     /locus_tag="ACF4ZO_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HFD5485693.1"
                     /translation="MAKKSKQMRAALEKVDSTKAYSVEEAVALVKETNFAKFDASVEV
                     AYNLNIDVRKADQQIRGAMVLPNGTGKTQRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINGGWLDFDVVIATPDMMAIVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADKAGNVQALIGKVSFDADKLVENFKAFHDVMAKAKPATAKGTYMANVSITSTQ
                     GVGIKVDPNSL"
BASE COUNT        33116 a        18825 c        21894 g        31218 t
ORIGIN      
        1 gaaaaaagtg taatcatttt ttgatttaca gttattatca tgtgttatct ggcgactgtc
       61 ctgtttacaa gtaagttcac aagtatggga taaaatagta taaactatag taaatactga
      121 atagtcatag aaaaatatcg gcataggtca gaaaagctga tatgtttaat actttttgcg
      181 gatatctact gtatttaaat gtatttgata tccttgtcaa ggatatacgt ctaaacaagt
      241 tcaaaacgaa atcatttgtg attatcttat caggagttga ctcttgataa gatttttgta
      301 tatcagtact gtggtacgtt tagatagctt ggcagtgaat ttatagagtg tcaaacaacg
      361 agtgttttgt gttacactaa ccattagaag agtctattgt tgagcatatc aaggtgttat
      421 cttttcgagt tgaggtatca tatctagtat atttaactat ggttttaaat gctatttcaa
      481 aaaaaatatg ataaaataga aagtactaat tattttggag atgacatgag tatcgatgat
      541 tataggccga cctatatggt agaggctatt tatgatttaa gagcaaatga tttgttgcgt
      601 catggtatta cggctgtttt agtggattta gataatacct taattgcatg gaataatcct
      661 gatggcacac cagaggttcg cgcttggctt gatgaaatga ctatcgcgga tattagcgtg
      721 gttgttgttt caaataataa acattctcgt gttgagcgtg ccgtttcacg ctttggtgtt
      781 gactttatta gccgggcttt gaagccattt gcttatggta ttgaaaaagc cattgctcgt
      841 tatggatttg atcgcaacga ggttatcatg gttggagatc agctaatgac tgatatcaga
      901 gctagtcata gagctggaat aaaatcagtt ttagtcaaac cacttgttgc ttctgatgct
      961 tggaatacta aaattaaccg ctggcgtgaa caccgtgtga tggcaaaatt agaagagaaa
     1021 tatggtaaat tatcatatca aaaaggaatt taatggaaga attattttgt ataggctgtg
     1081 gtatccagat tcaaactgaa gacaaagaaa aagctggttt tacgccagct gctgctttga
     1141 aaaagggtat ggaaacagga gaactctatt gtcagcgctg ctttagattg aggcattata
     1201 atgaaattac agatgtccat attaccgatg atgaattttt aagacttctt cacgaagtgg
     1261 gtgatagtga tgctcttgtg gttaatgtga ttgatatttt tgactttaat ggttctatta
     1321 ttccaggtct atctcgcttt atttctggta atgatgtctt actggttggg aataaaaaag
     1381 atattttgcc aaagtctgtt aaggatggta aagttactca atggttggcg gaacgtgcac
     1441 acgaagaagg tcttcgccct ttagacgtta tgttaacgag tgctcaaaat aaatatgcga
     1501 ttaaagactt gattgagcgt atcaatgagt tacgtaatgg tcgagatgtt tatgttgtgg
     1561 gagtcactaa tgttggtaaa tcaaccttga ttaatgcgat tatccaagag attactggta
     1621 acaaggatgt catcacgacg tctcgttttc ctgggacaac tcttgacaaa attgaaattc
     1681 ctttggatga tgggacgttc atttttgata caccaggaat tattcatagg caccagatgg
     1741 ctcattattt atcccctaaa gagctaaaaa tagtgagtcc taagaaggaa atcaagccta
     1801 agacgtatca attaaaccca gaacaaactc tctttttagg tggtttgtct cgctttgact
     1861 ttatcaatgg ggagcgtcaa gggtttacag ctttttttga caatcaacta gaattacatc
     1921 gtacaaaatt agctggagca aatgcttttt atgataagca tgttggaact ttgttaactc
     1981 ctccaggtaa gaaagagttg acagcatttc ctaaattagt tcgtcatgaa tttacaattg
     2041 atcagaaaat ggatattgtt ttttctggtc taggatggat tcgtgttaat ggtcaaaaag
     2101 actcaaaagc gatagttgct gcatgggctc ctgaaggggt cgctgtcatt gttcgtaaag
     2161 cgattattta aaaataaaaa aagaagttgg aaaaaaatgc ttacaagtaa acaaagagct
     2221 ttcttaaaat ctgaggctca tagcttaaaa ccgattgtac aaattggcaa aaatggatta
     2281 aatgaccaca ttaagactag tattcgtcaa gctttggatg ctagagaatt gataaaggtc
     2341 actttgttgc aaaatactga tgaagatatt catgaagtag cagagatttt agaagaagaa
     2401 attgggtgtg atacggtttt gaaaattggt cgtatcttga ttctctataa ggtttctgct
     2461 aagaaagaaa accgcaagtt gtcccctaaa gttaaagcaa tctagtcctt ttatttgtat
     2521 aggggctggt cttatgagat gaggactatt gtcgcgagaa ttttggagaa agtatggcat
     2581 tagaattgtt gacgcctttt acgaaggtgg aattagagga agaaaaaaaa gaaagcaacc
     2641 gcaaacagat tgggatttta ggagggaatt ttaatcctat tcacaatgca caccttgtgg
     2701 ttgcagatca agttcgccag caattaggat tagatcaggt gctattgatg cctgaatgta
     2761 aaccaccgca tgtggatgcc aaagagacta ttgatgagaa gcatcgtctt tgcatgttgg
     2821 aattggctat tgaagatgtt gaagggctag ctattgaaac ctgtgaactt gaacgtcagg
     2881 gaatcagcta tacctatgat acgatgcttt atttgactga gcagcatcct gatgtcgatt
     2941 attattttat tatcggagct gatatggttg attatttgcc aaagtggcac cgtattgatg
     3001 aactggtcaa actcgttcaa tttgttgggg ttcaacgtcc aaaatataaa gctggaacct
     3061 cttacccagt catttgggta gatcttcctt tgatggatat ttcttctagt atgattaggg
     3121 attttattaa aaaaggtcgt cagcccaatt atctcttacc taagcgggtt ttagactaca
     3181 ttactcaaga aggtttgtat caatgacata tgaagattat cttccttata gcaggaccga
     3241 actgttagca aaaattgcag agcagatgag ccctaaacga tttaaacatg tacttggcgt
     3301 ggaaaaggca gccttgtcct tggcagagtg ttatggttgt aacccagaca aagcagggtt
     3361 agcagctctt ttacatgatt atgccaagga gtgccctgac caggtctttt tagacttaat
     3421 tgacaagtac caattatctc cagaattagc taaatggaat aataatgtct ggcatggtat
     3481 ggttggtatt tataagattc aagaagacct agggctaaaa gacaaagata tcttgcgagc
     3541 tattgaaatt cacaccgttg gtgctgctga gatgaccttg ctggataagg tcttatacgt
     3601 tgctgattat attgaagaag gtcgcatttt tcctttggtt gatgacgcta gaaaaatcgc
     3661 gaagctcgat ttgaatcagg ctgttgccta tgaaacagtg aacactgtcg cttatttagc
     3721 ctcaaaagcg cagcctattt tcccacaaac tctggatacc tataatgcgt tttgcagcta
     3781 tttaaaggaa tactaatgga taatgatatg aggaataaaa tgaaaaaaga agaactctta
     3841 aaaattgttg tggaagcaac tgatgaaaag cgtgctaaag atattttagc cttggattta
     3901 gaggggttaa ctagtctgac tgattatttt gtgattgcga gtgcaacaaa cagtcgtcaa
     3961 ttagaggcta ttgcggataa tattcgtgaa aaggtaaaag aggctggtgg agatgctagc
     4021 catgttgaag gtaatagcca agcaggctgg gtcttgcttg atttgaccga tgtggtggta
     4081 catctttttt tagaagacga gcgttaccac tataatcttg aaaaattgtg gcatgaagcg
     4141 cctgctgtgg ctctagatgc ctatttagct taatgttaca aagagacctt gtcaatacga
     4201 cagggttttt gaggatgata atggaacata attatgaaaa atttgcgtca gtttatgatg
     4261 ctgtgatgga tgattctcta tatgacttgt ggacagattt ttcacttcga catttaccaa
     4321 agtctaaggg tcgaaatcgt ttgttagagt tggcctgtgg aaccggtatt cagtcagttc
     4381 gttttgctca agcaggcttt gacgtgactg gtttagactt aagtcaagac atgctggcta
     4441 ttgctaaaaa gcgtgcgcaa tctgctaaaa agaaaattga ttttattcaa ggtaacatgc
     4501 tggatttgtc acaggtgggg cagtttgatt ttgtaacctg ctattcggat tccatttgct
     4561 atatgcaaga cgaagttgat gttggcgatg tttttaaaga agtttatgat gttttagcaa
     4621 acgatggcat ctttattttt gatgtgcatt caacctatca aacggatgag tgtttccctg
     4681 gttattccta tcatgagaat gcagatgatt ttgcaatggt ttgggatacc tatgctgacg
     4741 aggctcctca ctctgttgtt cacgaactca ctttctttat tcaagaagac gatggacgtt
     4801 tttctcgctt tgatgaagtg catgaggaac gaacgtatga gttattgact tatgatattt
     4861 tgttggaaca agcagggttc aagtcattta aggtctatgc tgattttgaa gataaggagc
     4921 caactaagac cagcaagcgt tggttttttg tagcatataa atagaagaaa aaagtagcct
     4981 ttttagctat aggatttaat gaattatctt gaatgttact tatatgaaaa gagttcatta
     5041 ggcactaaat gctattatca aagcttagaa gtattggaga cattacgatt gacactatgt
     5101 ctgaaggttg ctaccaactt taaagaaagc atttgctatt atacgttgtg cttaagcatt
     5161 tgatttaact cttattagcc ctataaaaga ctatttagta caatttgagg agattctatg
     5221 actgttaccg gaattatagc tgagtttaat ccgtttcaca atggacacaa atatttgcta
     5281 gaaacagcag agggactaaa aattattgct atgtcaggaa attttatgca aagaggagag
     5341 cctgctctta ttgataaatg gattcgatca gagatggctc ttaaaaatgg tgcggatatt
     5401 gttgtggaat tgcccttttt cgtttcagtt caatcagcag actattttgc tcaaggagct
     5461 attgatattc tttgtcaatt aggaattcag caattagcat ttgggacaga ggatgtgatt
     5521 gattatcaaa aactgattaa ggtctatgag aaaaaatcaa agcaaatgac tgcctattta
     5581 tcgacgcttg aagatacact tagctatcca caaaaaacac aaaaaatgtg ggaaatcttt
     5641 gctggagtta aattttcagg gcaaacgcca aatcatattt tggggttaag ttacgcaaag
     5701 gctagcgctg gaaagcatat acaactatgt cctatcaagc gtcaaggggc tgcctaccat
     5761 tcgaaagaca aaaatcatct gctagcttct gcaagtgcca ttagacagca cctgaatgat
     5821 tgggatttca taagtcattc agtaccaaat gcaggtttac ttataaacaa tccccatatg
     5881 tcatgggacc attatttttc attcttaaaa tatcaaattc tgaaccattc tgatttaact
     5941 agtatttttc aggtcaatga tgaattggca agtcgtatta aaaaagcgat aaaagttagt
     6001 caaaatattg accacctagt tgacactgtt gctaccaaac gctatacaaa agctcgtgta
     6061 agacgtattt taacctacat tttggttaat gctaaggaac ctactttacc taaaggaatt
     6121 catattctag ggtttacctc aaaaggacaa gcacatttaa aaaaattaaa aaaaagcagg
     6181 cctctgatta ctagaattgg agcagaaact tgggatgaga tgacacaaaa agcagacagc
     6241 atctatcaac ttgggcatca ggatatccca gaacaaagtt ttgggagaat acctattata
     6301 ataaaaaatg agaggctcaa ttaaactcta attgagtttt tttgggggct tgactctaac
     6361 attacgttga tggtttatac ttcagttaat ccaatgagga aattttataa caataattaa
     6421 aaaagtcagt caaaagatat gctttcgaag aacaggctaa cgtttttaca agattatatc
     6481 agtaatcatt ttgacaattg tagtaatgga atgttaccaa aatttagaac gttgtgtgtt
     6541 atggatgaca agattttaaa ggaatactaa ttaaacggga ggtcgtgaac cggaagctgt
     6601 tgtcactcaa gcgccaaaat ctgtctgtaa cataatattg atgtatggga acttaattat
     6661 ttggttttta ttgtgatgct taaaacgatt ttatatttct attttaccaa agcttttcaa
     6721 agtgctataa taagggagtt agagtcaata ttagtaacgt taatgttgac aatattcaat
     6781 aaaatactat taaaaggaga caaaaatggg acgtaaatgg gcaaatattg ttgctaaaaa
     6841 aactgctaaa gatggagcaa catcaaaggt ctatgccaaa tttggtgttg aaatttatgt
     6901 ggctgccaaa caaggcgagc cagatccaga gttaaataca gctcttaaat ttgtcattga
     6961 tcgtgcaaag caagcacaag tgccaaagca tgttattgat aaagcgattg ataaagctaa
     7021 aggaaacaca gatgaaactt tcgtagaggg acgctatgaa ggttttggtc caaatggttc
     7081 aatgattatt gtggatactt tgacatcaaa tgttaaccgt acagcggcaa atgtacgtac
     7141 ggcttacggt aagaacggtg gcaatatggg agcttcagga tctgtatcct acttatttga
     7201 taaaaaaggg gtcatcgttt ttgctggtga tgatgctgac agtgtctttg agcaattact
     7261 tgaagcggat gtagacgtag atgatgttga agcagaagag ggaacaataa cagtttatac
     7321 cgccccaaca gatcttcata aaggtatcca agcacttcgc gataatggtg tagaagaatt
     7381 ccaagttact gaacttgaaa tgattcctca atcagaagta gtattggaag gtgatgacct
     7441 tgaaactttt gaaaagctta ttgacgcact cgaatcagat gatgatgttc aaaaagtgta
     7501 tcataatgta gcagatcttt aaattgacat agaataataa aaagagttga aaactatttc
     7561 agctcttttt aagtgatgct tttataagta agtaccaggt aacatagtcg ttgttagaag
     7621 ataatgaaca atagtaaatc agtatcagct tgataggaat caattattag tgaactctaa
     7681 ttaaaaatgg taaactagac acaagaacaa aaaggagaga taggatgatt aaaaaacaat
     7741 atttaggaag ggcaacaatt gccctagcat caacccttgt gctagcagct tgtgggtcat
     7801 caaaaaaagc tgagtcagga aatcagggga gttctaaaga agtcttattt gcaacggttg
     7861 gaacaacagc tcccttttct tatgaaaaag gtggtcaact aactggctac gatatcgagg
     7921 tggctaaagc agtctttaaa ggatcggatg attacaaggt gtcctttaaa aaaacagaat
     7981 ggtcttctat ctttacaggt ttggactcag gaaaatacca aatgggtggt aacaacattt
     8041 cctttaccaa agagcgttca gctaagtacc ttttttctta tccaatcgga tcaacacctt
     8101 ctgttttagt tgttccaaaa gacagtgata tcaagagctt tgatgatatc caagggcata
     8161 cgacacaagt tgttcaaggg actacaagtg ttgcacagtt agaagacttt aataagaaac
     8221 acagtgacaa cccggttact ctaaaattca ccaatgagaa cattactcaa atgttaacca
     8281 atttgagtga aggcaaggca gatttcaaga tttttgacgc tccaacggtt aacgccatta
     8341 ttaaaaatca agggttagat aatctcaaaa caattgaact cacctcaaca gagcaaccat
     8401 ttatttattt tatctttagt caagatcaag agaaattgca aagctttgtt aacaagcgta
     8461 ttaaagagtt gactgctgac ggaactctta gcaagcttgc caaagagcac cttggcggtg
     8521 attacgtgcc atcagataaa gagttgaaac ttcctacagc taactaaacc atctattaac
     8581 cagttattca tctagaagac tggtttttct gatcggaaat aatattatag tttatgaggt
     8641 tatgttataa aaattgcaaa tagccttaat caaaatgaga tgttaaagtg ctttttgaga
     8701 agtgaatatt gtataagaag tatgctttgg gttttagtcc tcaaatacca agtttttgtt
     8761 gactaaacaa ataaggatgg ttagtatagc atatagttta aaactatgct atatgctagc
     8821 cattatcaat ttgaaaacta tatctaatta agatacaata atgatcgtaa acaaaatgaa
     8881 tcgaggataa cgctatgtct tttaaaaaat ggattggaat agtcggaatc gctttagcat
     8941 caactgtatt ggttgcttgt tctgaaaaac aagatgataa aaacactcta actattgggg
     9001 tgatgacaaa aacagaatct gatcaagcga gatgggataa agttgaagaa ttattgaaaa
     9061 aagacaatat cactttgaag tacaaagaat ttacagatta ctcgcaacct aataaggcag
     9121 ttgctaatgg tgaagtcgat attaatgcct tccaacacta taatttctta aataactgga
     9181 ataaggaaaa taaggaacat ttggtggcca ttgctgatac ctatatcagc ccaattaacc
     9241 ttttctctgg aaccagtcaa gatgggaagg ctaaatacaa atcagtagct gatctgccaa
     9301 atggtgctca aattgcagta ccaaatgatg cgaccaatga aagccgtgcc ctctatgtgc
     9361 tgcaatcagc tggcctcatt aaattgaatg tgtctggtga tcaattagca accattgcca
     9421 atatctcaga gaacaaaaag aaattagata tcaaggaatt agatgctagc caaacggcac
     9481 gtgctttagt atctgctgat gcagctgttg tcaataatag ttacgctgtt cctgcaaaaa
     9541 ttgactacaa aacctctctt ttcaaagaaa aagcagatga caattcaaaa caatggatta
     9601 acattattgc aggtcaaaaa gattgggaaa aatcagagaa ggctgatgct attaaaaaac
     9661 tcatcaaggc ctaccaaact gatgaggtga agaaagtcgt ggaaaaaact tcaaatggta
     9721 tagatgtatc cgtatggtaa attttagcca ttgctataac aagagtgtgg tcgtgtttaa
     9781 aacacatgct ttcttgcatg cttgaggaag agtttacgat taatttacct ttagaaagct
     9841 atttaagacc ttttcccttt taggatttag aaaccttggg aagactattg catgttatct
     9901 taatagtcat gattctgcag gcgatgaaaa cattgctatc gtagattact gtcgccatat
     9961 cgtactaata gaggagttat taaaatctta tgaatgaagc aataattcaa ttagatcata
    10021 ttgatattac cttccgtcaa aaaaaacggg ttatcgaagc tgttaaagat gtcacggttc
    10081 atatcaatca aggagatatt tatggcattg ttgggtattc aggtgccggg aaatcaactc
    10141 ttgtgcgtgt gattaacctg ctacaggcac caacaaacgg gaaaatcact gttgatgggg
    10201 atgtgacctt tgaccagggg aaaattcaat tgtcagccaa tgcccttcgt caaaaacgac
    10261 gtgatattgg catgatcttc caacatttca atttgatggc ccaaaaaaca gccaaagaaa
    10321 atgtagcatt tgcgctccgc cattcatcgt taagtaagac tgagaaagaa cataaagtta
    10381 tcgagctgct agaacttgta ggtttatcag agcgagcaga taactaccct gctcagttat
    10441 cgggtgggca aaaacaaagg gtggctattg cgcgtgctct agctaacgat ccaaaaattt
    10501 tgatttcaga tgaggccaca tcagcactag atccaaaaac cactaaacaa attttggcgc
    10561 tcttgcaaga attaaaccgc aaacttggcc ttaccattgt tatgattact catgaaatgc
    10621 aaattgttaa ggatatttgt aatcgtgttg ctgttatgca aaatggtgtt ttgattgaag
    10681 aaggttctgt ccttgatatc ttttcaaatc caaaagaagc cttgacacag aaatttatca
    10741 caacagctac agggattgat gaggctttag aaaaaattaa ccaacaagac attgtcaaac
    10801 atttgcctgc aaatgccctt ctagctcagt tgaaatatgc aggaacttct acggatgagc
    10861 ctctacttaa tagcatttac cgtcagtttg aagtgacagc taatattttg tatggcaata
    10921 ttgagatttt agatcatatt ccagttggtg acatgattgt tgtcttggaa gggcaagctg
    10981 aaaatattct tgcggctgag aaagccttgc atgaagctgg tgttgatgtt agtattttaa
    11041 agagaggagc ctagatgtca cagttaattc aaacttattt gccaaatgtt tatgaactcg
    11101 gatggtctgg agatgctggt tggggcttag cgatttggaa tactttatac atgaccattg
    11161 tgccttttat tgttgggggt gctattggtc tcttattagg cttgttatta gttttaacag
    11221 gaccggacgg tgttattgaa aacaaaacga tttgttgggt cattgataaa gttacctcta
    11281 tttttagagc cattcctttt gttattttga ttgctatttt agctagcttt acctatttgc
    11341 ttttaagaac aactttagga gcaacagcgg ccttggtacc tttaaccttt gcgacttttc
    11401 ctttttatgc ccgtcaggtc caagttgttt tttcagaatt agacaagggt gttattgaag
    11461 cagcgcaagc ttcaggtgct actttctggg atattgtcaa agtgtatctc agtgaaggtt
    11521 taccagatct tattcgtgtt tctacagtca ccttaatttc tttagttggg gaaactgcca
    11581 tggcaggagc tatcggtgct ggaggtttag gaaatgtagc gatttcttat ggttataatc
    11641 gttttaacaa tgatgtgact tgggtagcga ctattattat tcttttaatt atttttgtta
    11701 tccaatttat tggtgatagc ttgaccagac ggtttagtca taaataaaca acaacaccct
    11761 aagtttttac ttagggtgtt gttgtttaga tgatgtcatt agcttttctt cttttcttcg
    11821 ttttacttag aatgaatccg agtaggaatc caataatggc aaagataatc catcctattg
    11881 aaaattgtcc aagtggaact gttttttgga agaaagttgt cactggctct ggcaagttga
    11941 agagaccagt catttgtgat agtgttagga gtgcatcaaa tatggcagga ataaaggtta
    12001 gaccaattgt agttcgatag acaataggat cattattgaa gtatttttgt gccaaaacaa
    12061 ggaaaattaa atcaactgtt aatgggtata aaaggaataa aacaggagct gaccagttga
    12121 taatgactga taagccacca aaataaaaga aagctgatag taaagtaaag atagttgccc
    12181 aagcaatatg agataaagca ggcactaatt tatggaagta ttcagcactt gacgtgatta
    12241 agcctgttga agtggttaga caggccagga aaatcacaac agctagaaat gcttgtccga
    12301 tgccacctag gtaaaaacga gaagcatgac ttaagatttg accgccatta actggattac
    12361 catgaagggt aaagctgcca tcactaaaag gaaataatga ttgtgatgtt gctccaatac
    12421 gaccgacaaa gatatagaca agtgctaata gcaaaatggc aatagcccca gaaataagtg
    12481 ttattttggt cacttctttg tccgtcttag cgccaaattg tttggtagcc tcaatgacta
    12541 aaatagcaaa aacaagagaa gctagtgcat ccatagtgcc ataaccttga attaatcctg
    12601 ctataaaagg aaaatcttta aaggcattat taacaccgac cccagcgtta aaagcatcac
    12661 cgtaatttcc agcaggatgg acaaaggacg cgataaccaa aatagaaata acaactaaca
    12721 acgttggcgt taaaaatttt ccgatatttt cagctagctt actaggtttg atagcaagga
    12781 agtaggacag accaaaaaat agtatagcat aaatagcttt attggttgta ttatctccta
    12841 agataggagc gataccgact gaaaaagaag tggctcctgt tcttggaata gcaaaaaatg
    12901 gaccaataga taaatacaaa atggaagaat agaagattgc ataccattta gagatggggc
    12961 gtgctaaact ttcaacatcg cctgatccag atttagcaac agcaatgaca ccgagtaaag
    13021 gcaaggagac accagttaaa caaaaaccaa tgatagacca tagaatctga tgacctgagt
    13081 agatgcctaa aaaagctggg taaatgaggt ttgctgctcc aaaaaatagt gcaaatagca
    13141 tgaatccaat gacgatatat acattttttt gtttcattta taaatagtct ttctattgat
    13201 actaatccga agattctaac aattttaatt atattatgtg tcaaaataac aacaaaggtt
    13261 attatatcta agattacttc gatagtcaat agaaattgac tgaaaattct tagcacaaaa
    13321 aatggttaag atatgtagct cattcgattt gacgaataga tagaattata ttattataaa
    13381 aaacatgtaa ctttagtaag gatgtaacgt atgaaaaaaa tatatgattt atgggttagg
    13441 gttagtctaa tcaaaaaaat aggtatcggt gttgtaatag gagtcatgtt gggcattttg
    13501 gctcctgatc ttacaggttt tagtatttta ggaaagttat ttgttggtgg tttaaaggct
    13561 atcgcacctt tgcttgtatt tgctttggtt tcccaagcca tctcccatca gaaaaaaggg
    13621 agacagacta atatgacatt aatcattttt ctgtatttat ttggtacctt tgcgtcagct
    13681 ttagtagcag tactgacagc ttatctattc cctttgacgt tagtgttaaa tacacctgta
    13741 aatacagaat tatcaccacc tcaaggtgtt gctgaagttt ttcagtcact tctattaaaa
    13801 ttagtggata atccgatcaa tgctttggct actgccaatt atattggtgt gctatcatgg
    13861 gcaattattt ttggactagc attaaaggct gcaagtcaag aaacaaagca tcttataaaa
    13921 acagcggcag aagttacttc acaaatagtt gtttggatca tcaatctggc acctattggg
    13981 attatgagtc tggtgttcac tacgatttct gaaaacggtg ttggaatctt atctgattat
    14041 gcttttttga tactagtttt agtaggaaca atggtttttg tcgccttagt ggttaatcca
    14101 cttattgcgg ttttgattac acgacaaaat ccttatcccc ttgtcttaag atgtttacgt
    14161 gagtcaggtc ttacagcatt tttcacacga agttctgcag ccaatattcc agtcaatatg
    14221 caattatgcc aaaaaattgg attgagtaaa gatacttatt cagtgtcaat tccacttgga
    14281 gcaactatta atatgggtgg ggcagcaatt accatcaatg tcctaacgct tgctgctgta
    14341 cacacttttg gtattcctat tgattttcta acagccctct tacttagcgt tgttgctgct
    14401 gtctctgctt gtggtgcttc tggtgttgct gggggatcgt tgttacttat tcctgtagca
    14461 tgtagtttgt ttggcatttc aaatgatctt gcgatgcagg tggttggtgt tggttttatt
    14521 gttggtgtta tccaggattc ttgtgagaca gccttaaatt cgtcaaccga tgttcttttt
    14581 acagctattg ctgaaaatgc tttttggaaa cgtaaaaaag cctagctagg tttaacatag
    14641 taaaaaacat ccttggaaaa cgccaaggat gtttttttat tatttaagat agccaagata
    14701 atcaaatttt tcaaaggtgt ggtcattagc gatggccaca atgatagtat tcggttctaa
    14761 aggttcgaaa ggtttgacat tggtatctaa ggttttaact tctttttgac gcatgccaat
    14821 cacatttaac ttatatttac gacgaacatc tagttcggaa agagattgtc cttcccagct
    14881 tttaggaatg acaaattcaa tcatcgaaat accatgttcc aaatagatga tgctttcgat
    14941 atgacgtctt aacagatttg aagctacacg ttttccagaa tcacgttcag gggtgatgac
    15001 tttagttgct ccgatgccat atagaacttc ttcaaaaatt ttatttttag ccttggcaat
    15061 aatggttgga acaccgagtt ttttacagtg catgactgca agaacagaag attccaagtt
    15121 attccctgaa gcgataacga cagtatcaca atgttcaatc cctacagcta atagaaattc
    15181 tttgtcagta atatctccaa cagcggcttt agtgaccaag tcggccacct ctttaacatg
    15241 actttctctg atatcaatag caataacgtc ttgatcaaaa ttacttaatt ctctggcaac
    15301 agtacggcca aaaataccaa ggccaagaac accgacagtt ttacgtttta acatgttttc
    15361 tccttaaccc actaaaatat cagtagtggc atattgaatg gttttttctt ttcgttgaat
    15421 cagactgatg aggacagtaa ttgggccaac gcggccgacg aacatcaaga caatgacaat
    15481 aagacgtcca gcagtagaca attgtggtgt caaatccata gataccccaa ctgtcgcgat
    15541 ggcagaaata gattcaaata agagtggtat aggagcgata tgaggctcca cgctaagtaa
    15601 taaaataaaa cctatcataa gaactgcaaa aaagaagata agaactgtca tggtctgctt
    15661 aattgtctta tttgcgataa ttcggttacg aaaggtaact tctgattgcc ctgaaagttc
    15721 cgctttaaag agtaagaaag taatggcagc agtcgtcact ttaatcccac cagctgttcc
    15781 accaggagca ccaccaataa ccatttgaat catataaaga atgttagttg gtgctagggt
    15841 atcgttataa gagattgttg caaagccagc tgttctcata gtgactgttt gaaaaaatga
    15901 aaccataagt tgctgatgta aactaaaatt ggcaatggtt ttgctgttat ctttttctaa
    15961 aaaccaggtt aagaaggtcc caagaaaaag aataacagct gtggtttgta gtactagacg
    16021 agactgattg gataatttac gaaaagttgc cccataacaa tgaggtcttt caaaaaagta
    16081 ttttttaaaa gctactccta aatcaaccca aaccgcaaaa ccaagtccac cagagataat
    16141 caagaacgta atgataacat ttaatgtagg atttaacata aagtctttta aactagaaga
    16201 tcctaaattg tcaaaaccag cgttacaaaa tgccgacaca gctagaaaaa tactattgaa
    16261 gataccattt ttccacccga agcgagggat aaagtcaatc atgataacta tcgcagcaaa
    16321 ggcttctaga ctaaaggtta ctttataagc aaaaaaaagg tagtgcttta aatctttgct
    16381 atcacctcga tttaacgctg attggagcaa ggtttgatcg ctcaatcgca tttttcgctt
    16441 gagggcaaaa gtactcacag ctattaacgt caccaagcca agaccaccaa tctgcattag
    16501 tgccatagca atggtttgtc cgataccgtt atacacttca gcgacgggaa caacagaaag
    16561 tccagtcaca caaaccatgg aaaccacatt aaagaaatga tcaagataga cggtattagg
    16621 accattttga taatgggtaa agggcatgga taacaagaga gtcccaatca gaatcacaat
    16681 ggcaaaacta aatgttaagc gctgtgtgac tgaaagagat ttaataaaag agcgtttcat
    16741 gtttcctcca gacataatat ctcctactat aataacaaaa ataagttaaa aaagctaagt
    16801 ttcatcttag cctttggtac tattttatag aggttttttg ttaggcaagc cagcttttct
    16861 tggatacttg ttaggtgttt cctttttctt ctcaacaatg gtgatgaagc gagaatctcc
    16921 atttggcaat tggtagctat ggtttttaat gactttacca aaaagaagac aaagagcatt
    16981 cttagcttct tctaactctt ggtcagcagc ttgtgccttt aaggcgatta attttcctct
    17041 aatttttaaa aaggggatgg ttaattcaga tagaacctgc atccgagcaa ccgctctggc
    17101 agtaacggca tcaaattgac ctcgaaaggc cttgtcctgt ccgaaatctt ctgctctacc
    17161 atgaaaaaaa tggacatttt ccaagcccaa ttcctgagca aggagtgtca gaaaagaaat
    17221 ccgcttatta agagaatcaa taatggtaac ctcaaggttt gggaaaagaa ttttcatggg
    17281 taggctagga aaaccagctc cagctccaat gtccaataat ttgattggtt cattagctaa
    17341 aaagccctgt aaaataggag cgatggaatc ataaaaatgc ttgaggtaaa cctcattttc
    17401 ttctgtaata gctgttaaat taattttagt gttccattcc actagtaatt tgaagtaggt
    17461 gtcaaattgt tctttttgtt tcgatgataa agaaaaacca tcttcctcta gtgttctgta
    17521 aaagtcttgg ggtgtcattt gaatcctctg tttttgatag ttgttaccat tttatcataa
    17581 aatagcccat aacaaaattt aataaatcat cagaaataac acctcattac ttgctattag
    17641 cctagaaatt gctataattg agacacaaag attaaaggag acccactatg ccaacagttt
    17701 tgattatctt agtcgtttta ggagtgcttg cgctatggtt aatgattagt tacaatagcc
    17761 tggttaaatc tcggatgcac acaaaagaag cttggagtca gattgatgtg caattaaagc
    17821 gtcgtaatga cttgattcca aatcttattg aaaccgtaaa gggatatgct agctacgagc
    17881 aaaagacatt tgaaaaaatc actgatttgc gtgcgcgtgt tgcgaatgcc tcaactcctc
    17941 aagaaaccat ggcggcttct aacgaattga gtaaacaagt gaccagtttg tttgccgttg
    18001 ctgaaaatta cccagactta aaagctaacg aaaacttctt gaaattacaa gaagagttga
    18061 ccaatacgga aaataaaatc tcatattctc gtcaactcta taattcaaca acgtctaatt
    18121 acaaccttca attagaatct ttcccaagca atatcgctgg taaattattt ggttttaaac
    18181 caagtgaatt cttacaaaca ccagaagctg aaaaagaagt tccaaaagtt gaatttaact
    18241 tttaaatatg aaattatcat ctagtaggca atcataagag aaaggagaat tatgctttat
    18301 caacagattt cacaaaataa gcaacgaaca gttgttttat tagttgtttt cttcgctctc
    18361 ttagcactta ttggagcgtc agcaggctat ctgctgttag ataattatgc catgggcttg
    18421 gttcttgctc ttgtcattgg ggtgatttat gctaccagta tgatttttca atccaccagt
    18481 cttgtaatga gtatgaacaa tgctagagaa gttacagaaa aagaggctcc aggcttcttc
    18541 catattgtcg aggatatggc tatggtagct cagattccga tgccgagagt ttttattatt
    18601 gaagatcctt ctttaaatgc ttttgcgaca ggatctagcc ctcaaaatgc tgctgttgca
    18661 gcaacgacag gtttacttga agtcatgaat cgtgaagaac ttgaaggtgt tatcggccat
    18721 gaaattagcc acatccgaaa ttatgatatc cgtatttcga ctattgctgt agctttggcg
    18781 agtgctgtta ccgttatttc tagtatcggt gggcgtatgc tatggtatgg tggcggttct
    18841 cgcaggcaaa gagatgacgg agatgatgat gttttaagaa tcattacatt acttttgtcg
    18901 ttattatctt tgcttttagc gcccctagta gcaagtttga ttcagttggc tatttctcgt
    18961 caaagagaat atctagctga tgctagttct gttgaactaa caagaaatcc ccaaggtatg
    19021 attaaggctc ttgaaaaatt gcagttatct cagccaatga agcatcctgt tgatgatgct
    19081 agtgcggcct tgtatattaa tgagcctcgc aaaaaaagga gcttcagttc attattcagc
    19141 acccatcctc ctattgagga gaggattgaa aggttaaaaa acatgtgagc gtttggggtt
    19201 tttgctcaag cctcactttt ttatgtcttt gggcagataa tctaaaatgg caggaattat
    19261 caaaaatatc tgaacaaaaa gaaaaaaatg agtgaaacaa tggttaaaaa tagaatgatt
    19321 taaatcttaa aattaaaaaa cgtcagaaaa taaatgcaaa actattgaca aatcttttag
    19381 atagtagtaa aaataaatga gagttttatt aggagaagat gatgttagct atttccgaaa
    19441 tcagaaaaca cccagacggt ctctcgtttg atcgtttatg tgatgtcaaa agtatgttac
    19501 ttgagcgtga ccaacagatt attgacataa aggcagttaa agctgtcggt aatgttcgct
    19561 atgataaggg gctttatctg ttagattatc aattgagtta cgaagtgata ttaccgtcta
    19621 gccgttctat ggttccggtc tgtttaagtg aagtccaaca cattcaagaa ttatttatag
    19681 aggcgacaga tttagctgat aagaaagagt tggttgaaga caacctggta ttagttttag
    19741 acaaagacgc tattaacctc gaagaaagta ttgtggataa tatcttactt gctattccgc
    19801 tacaggtctt gacagaggaa gaaaagaaat caaaagagtt gccagcaggt caaaattggg
    19861 cagttttgac agaagaagac taccagtgtc taaaagaaga aaagcaaaaa gaaaataatc
    19921 cttttgctag cttgcaaggg ttgtttgatg aataaaactg aatattaaag atgtctgtaa
    19981 tttttatttg aaaaaacagc tattctttga tatactcttt agagaatatg gttacttatc
    20041 taaagtagaa ggtattttga ccatagaggg caaagaaggt aatgactatt agatgcttca
    20101 tattttattc gctagaagac tatttgacca ttagaactga aatagtctag gatatgagat
    20161 ggatttcata gttttctttc tgggagaaaa agatagatta agaggataag ggttggtata
    20221 aatgacaaag aaaattttaa ttattgaaga tgaaaagaat ctggctagat tcgtttctct
    20281 tgagctgcaa catgagggtt atgaagtcat tgttgaggtc aatggtcgcg aagggttaga
    20341 aactgctttg gaaaaagagt ttgatttaat cctgcttgac ttaatgttac cagagatgga
    20401 tggttttgaa gtgacccgtc gtttgcaaac cgaaaaaaca acgtatatca tgatgatgac
    20461 tgcgcgtgat tctattatgg atgtggttgc aggtttagac cgcggtgcag acgactatat
    20521 tgttaaaccg tttgccattg aagaactact tgcccgtatt cgtgctattt tccgccgtca
    20581 agatattgaa tctgagaaga aagtgcctag tcaaggtatt tatcgagatc tagttttaaa
    20641 tccacaaaac cgttcagtta atcgtggcga cgatgagatt tctctcacta aacgtgaata
    20701 tgatttgctt aatattttga tgactaacat gaatcgcgtc atgacacgtg aagaattatt
    20761 gtcaaatgtt tggaaatatg atgaagccgt tgagactaat gttgtagatg tctatattcg
    20821 ctatctccgc ggcaaaattg acattccagg caaggaatct tatatccaaa cagtgcgtgg
    20881 catgggatac gttattcgtg agaaataagt catatggaaa atcagaaaca aaaacagaag
    20941 aaatataaaa actcgttacc aaaacgacta tctaatatct tttttgttct ttttttctgc
    21001 attttctctg cctttacact gattgcctat agttcaacaa actatttctt attgaagaaa
    21061 gaaaagcagt cagtttttca agctgtaaat attgttagag ttcgtctttc tgaggtggac
    21121 tctaatttta cattagagaa cttagcagaa gttttgtaca aaaacgataa aacacatctg
    21181 agaattgatg acagaaaggg cagtcgagtc attaggagtg agcgcgatat cacaaatact
    21241 ctagatgcga atcaagatat ttatgtctat aacattgata aacagatgat ttttaccaca
    21301 gataacgaag aatcatctcc tggcttgcat ggtcctatcg gtcgggtgta tcacgaccat
    21361 atcgaagatc agtatcgtgg attttccatg acacaaaagg tatattctaa tcggactgga
    21421 aaatttgtgg gctatgttca agtctttcat gatttaggca attattatgt cattagagca
    21481 agactgctgt tttggctact agttgttgag ttatttggca caagcttagc ctatttaatc
    21541 atcttaatta ctacgcggcg ctttttgaag cctttacaca atttacatga agtgatacgt
    21601 aatatctctg aaaatcctaa taatttaaac ctgcgctcag atatttcgtc aggagatgaa
    21661 atcgaagaat tgtctgttat ctttgacaat atgttagaca aattggagac atatactaag
    21721 ttgcaatcac gttttattag tgatgtcagc catgaattac gaacaccggt tgcgattatt
    21781 aaagggcata ttggtctctt acaacgttgg ggtaaagatg acagtgatat acttgaagaa
    21841 agcttgacag caacagcgca tgaggctgac cgtatggcaa tcatgattaa tgatatgtta
    21901 gacatgattc gcgtacaagg ctcatttgag ggacatcaaa atgatatgac agttttggaa
    21961 gattctattg aaactgttgt tgataatttt agagttttaa gagaagattt tatctttaca
    22021 tggcagtcag aaaatccaaa aacgatagcc cgtatttata aaaatcattt tgagcaggct
    22081 ttgatgattc ttattgacaa tgctgtgaag tattcccgta aagaaaagaa aatcgcgatt
    22141 aacctttcag tgactggcaa acaagaagct attgttagag ttcaagataa aggcgaagga
    22201 atttctaaag aagatattga acatatcttt gaacgctttt atagaacgga taaatcacgt
    22261 aatcgaacaa gtactcaggc tggattaggg attggcttgt ctattctcaa gcaaattgta
    22321 gatgggtatc atttacagat gaaggttgaa agtgaattaa atgaaggttc agtgtttatc
    22381 ttacatattc ctttggccca gtctaacgag agttagagta gcttaaggca ttgttaatgt
    22441 gacaggtata gtatgtaatc attagataat agtagcagtc ttttgccaca actggttaga
    22501 agctgatgct atttttttag caatgatgga tgacatgaaa gaaatactgt caatcgcgat
    22561 gccttttgtt atccttgaga atatggtaaa atagtgtatt agattaattt gatagaattg
    22621 gggtgtttgc gtgcgttgtc caaaatgtaa ttaccataaa tcgagtgttg ttgacagtag
    22681 acaggctgaa gacggcaaca ccattcgtcg tcgaagagaa tgtgaacagt gtcatactcg
    22741 ctttactacc tttgagcgtg ttgaagaact ccctttatta gtcatcaaaa aagatggcac
    22801 acgagagcaa ttttctagag ataaaatatt aaatggggtt gtccaaagtg cgcaaaaacg
    22861 acctgtctcg agcacagata ttgaaaatgt catttctcgt attgaacaaa aagttcgaac
    22921 aacctacgaa aatgaagtgt caagtactgc tattggtaat ttagtgatgg atgagttggc
    22981 cgaactcgat gaaatcacat atgtacgctt tgctagtgtc tacaagagtt tcaaggacgt
    23041 tgatgaaatc gaagaacttt tgcaacaaat tacgaatcgc gtacgcggaa agaaaaaacg
    23101 tttaaataat gatgaaacca attgatactt ttacatatct aaaacgcaac aaagtaactc
    23161 ttgattcggt gactttaata cagttgtact ttccaattat tggaagtgac gcggtctcta
    23221 tctaccaata ctttattcac ttttttgacg atggtttaca acgtcataaa ttcagcgata
    23281 ttttaaatca cctacagttt ggtatgaaac gttttgaaga tgctcttgcc atattgacag
    23341 caatggaatt agtgagtgtg tatcagctat cagatacata tctcattacg ttgcaccagc
    23401 cgcttagccg tgacttgttt tttcaacatc cagcttattc tcgattatta gaacaaaaga
    23461 ttggagaggt agctgtctct gagttgcagg taactgtccc aagtcaagca agaaatattt
    23521 ctaagcgatt ttcggatatt tttggggtgc aaggagattt gacgaacgta cctcaaaagc
    23581 cacaaaagaa ttttgacctt tcaagtttcc agcaattaat ggttcgtgat gggttacaat
    23641 ttgaagataa tcaaaaagat atcattagcc tttacagtat tgctgaacag tatgatatga
    23701 cgtggtttga tacttatcaa atagctaaga cgacggctgt taatgggaaa attcgacctg
    23761 aacgcttatt ggctaaaaaa aatcaaagca tgacaaaacc aagcaaagaa aatttttcac
    23821 aggctgagca aattattttg cgagaagcaa agcaagacag tgctttagtc tttttggaaa
    23881 aaattaaaaa ggctagacgt gcaacgatta ctaaggatga acgcatttta ttgcaaacat
    23941 tggccaaaat gaattttctt gatgatgtta tcaatgtcat ggtgctttat acctttaata
    24001 agacaaaatc tgctaattta cagaagagtt atgtcttaaa aatggccaat gatttcgcct
    24061 accaaaaggt gtcaacggct gaagaagcta tagtggtttt gcgagccttc acggatcgtc
    24121 aaagtcgtcg gcaatcaaaa gtaaaaataa gtcaaagcaa tgtgcctaag tggagcaatc
    24181 ctgattacca agagacaaca agtcaagaag agcaggcgaa actagatcag ttcaaacagg
    24241 ctgctttgaa gaggttagaa aacctaggaa aagggggtga ctagatggaa aagattggag
    24301 aaaccatggc gaaattgggt caaaacactc gtgttaatag cgaccagttg attcaaacca
    24361 ttttagcgga tcctgaagta gcaagcttca tcagtcaaca tcacctatct caagagcaaa
    24421 ttaaccttag cttatctaag ttcaatcaat ttttggtgga acgccagaag tatcaactca
    24481 aagatccctc ttatattgct aagggctatc agcctattct agctatgaat gagggctacg
    24541 ctgatgtgtc ttatttggaa accaaagaat tggtagaagc tcaaaaacag gcagctatct
    24601 ctgaacggat tcaactggtc agtttgccaa aatcctatcg ccatattcat ttatcagata
    24661 ttgatgttaa taatgcgagc cgtatggaag ctttctctgc tattttagat tttgtggaac
    24721 aatacccatc agcagagcaa aaaggcttat atttgtacgg agatatggga attggcaagt
    24781 cttacttgtt ggctgctatg gcccatgaat tgtctgagaa aaaaggtgtg tcaacgaccc
    24841 ttctacattt tccgagcttt gccattgatg taaaaaatgc catttcaaac ggctctgtta
    24901 aagaagaaat cgatgcggtc aaaaatgtac cagtgctcat tttagatgat attggtgcag
    24961 agcaagccac ttcttgggtc cgtgatgagg tgttgcaggt gattttacaa taccgtatgt
    25021 tagaggaatt gccaaccttc tttacctcta attacagctt tgcggatttg gagcgaaaat
    25081 gggcaaccat caaaggaagt gacgaaactt ggcaggccaa acgtgtcatg gaacgcgtgc
    25141 gttatttggc tagagagttt catttagaag gggctaaccg ccgttaagtt tgagatagca
    25201 atcaagaaga atagctacac gtatgagtga gtgaaagaaa aggagaatca tggttttacc
    25261 taccgttgcc attgtgggcc gtccaaatgt gggcaagtcc accttattta atcgaatcgc
    25321 aggagagcgc atttcaattg tagaagacgt tgaaggggtt actcgtgacc gtatttatgc
    25381 tactggggag tggcttaacc gccaattctc attgattgat acaggtggta ttgatgacgt
    25441 tgatgccccg tttatggagc aaatcaagca ccaggctcaa attgctatgg aagaagcgga
    25501 cgttattgtc tttgtcgttt ctggtaaaga aggggttacg gatgcagacg aatatgtgtc
    25561 taaaatccta taccgaacca ataccccagt gattttagct gtcaacaaag tggataatcc
    25621 tgaaatgcgt aatgacattt atgattttta ttcacttggt ttaggggatc cttatccagt
    25681 ttcttctgtt catggtatcg gaacagggga tgtcttggat gcgatcgttg aaaacttgcc
    25741 agtagaagag gctgaagaaa atgatgatat tattcgcttc agtttaatcg gtcgtcctaa
    25801 tgttggaaaa tctagcttga ttaatgctat tttaggtgag gatcgcgtta ttgctagtcc
    25861 tgtcgcaggg acaacacgtg atgccattga cacgcatttt acggatgctg acggtcaaga
    25921 atttaccatg attgacacgg ctggaatgcg caaatctggc aagatttacg aaaatacaga
    25981 gaaatattct gtcatgcgtg ccatgcgtgc cattgaccgc tccgatgtgg tcttgatggt
    26041 tatcaatgct gaagaaggta tccgtgaata cgacaagcgt atcgctggct ttgcacacga
    26101 agctggtaaa ggaatgatta tcgtggttaa caaatgggat accattgaca aggataatca
    26161 taccgttgct aagtgggaag ccgatattcg tgaccaattt caatttttga catacgctcc
    26221 gattattttt gtgtcagctt tgacgaagca gcgcctcaac aaattgcctg acttgattaa
    26281 acgtatcagt gagagtcaga ataaacgtat cccatctgct gtcctcaatg atgttatcat
    26341 ggatgctatt gccattaatc caacaccaac ggataagggt aaacgtttga aaattttcta
    26401 tgccactcaa gtgtcagtaa agccaccaac atttgtcgtc tttgttaacg aggaagaatt
    26461 gatgcacttc tcttatctac gcttcttgga aaaccagatt cgcgcagcct ttacctttga
    26521 agggacaccg attcatctga ttgctcgcaa acggaaataa gaaatgaaca tcaactaaaa
    26581 tgctgaccta agaaataatc tcatcattga taaggactgt gctgtgtatg ttacaggaga
    26641 cagtcctttt tataatacct ttaagggtgt agacggaaga ttagtagcaa acaaagaaaa
    26701 aggattttga caagaaatat cagtcggttt ttgctataat gaaaggataa gcaaaaaggt
    26761 ggaaaaatga tggctagatt aattccagga cgagtaagga atgaaggtat taagctttat
    26821 gagcaaggtt tagtctcatt ccaagatgat aataaaggca ttcttcaaat agaagtggag
    26881 acttatcagg ttcaatatgg agcagatgat gaggatatca cttgtcaatg cgacacattt
    26941 catatgaaac attattgcaa gcatattgca gcagtcgagt attttttaaa aaatgatcaa
    27001 aaaggtaagc tttttttaaa acagttaaca aatcaaacaa aaatcaaaga aacaacaaag
    27061 aaaatgacat cttttggtag cctcttttta gatagcttag ccatgaatga agatgattct
    27121 gttaaataca ggctgtctgc tcttggtagt cgaagccctt tttcgtcaga ttactggtgg
    27181 agtctgaaaa tcaatcgttt accagatgat cgttcttatg tgattcgaga tattaaaggc
    27241 tttttgcagc ttattaaaaa agaaggcttt tatcagattg gaaaaaatta ttttgaacaa
    27301 ctttcatggc tgcagtttga cccatccagt caagacctta ttgagttttt atggcgctta
    27361 gcatctgata ctgacaaagg ggacaatgag aacatttttc caaatcatgc aaggcatttg
    27421 cgcttaccta gtggtttttt tgaagaaggc attcactatt tgacgtcact ttatgacttt
    27481 acttttgagg ggccttctca aacttatcat catctttttg tccgttcttt ggaagcagag
    27541 gcaggccttt atgagtttaa agtggaagtg catcgcaaat ctattgaatt gcaaattgct
    27601 gaaaaaaatg tgcaatacct ctttgataat gactatcttc tttatcaaga taccttttat
    27661 cacttgacgt taaagcaacg aaaaatggtt caggctattc gtagtctgcc cattgaggcc
    27721 gacttggcta aacatattca ttttgatttg gatgatcatg cgaaattagc tgcaagctta
    27781 tcagatttta aacagatcgg tctagtagag gctcctaaaa gctttgctat tagagacttt
    27841 gaggtgactt ttcaatttga tttgttaaat cgagatgaaa tcagttgtca gcttatgttt
    27901 gattatggca attaccaagt tagtgacaaa gcaagtttag aagcacttcc ttttgctagt
    27961 catttaaaaa aagaagaaaa aatcaatcgt tctttacttg cttttggctt ctcgccacaa
    28021 ttttactcaa aaaagcgact aacaagtgca aaagagctct atactttttt tgaagaaaca
    28081 gttccatgtt ttgagcgctt aggtaatgtt gcgttgagta cagctatcca agcattacaa
    28141 gtgaaagaaa tgcccaagat cgctattaaa cgcaatcagg ggttactaga catctcgttt
    28201 gatttttcaa ccattattga aaatgatatt gaccaagctg ttacagctct ttttcaaaat
    28261 aatccttatt ttgtgagtca aacaggtcaa ttagtggttt ttgatgatga aactcaaaaa
    28321 gttagcaaaa gtttacaaga attaagagca agacagctaa aaaatggtca cttgcaactg
    28381 gatggcatta gagctctaca agtatccaaa ctttttgaag gcatgacatc tgttcatttt
    28441 tcaaaggaat tagaagagtt agcctatcat ttgcagcatc ctgaaacttt ttcaataaaa
    28501 ccgttaccag ttaaggctca aatgcgagat tatcaacgca acggtgttca gtggttatca
    28561 atgctcaatc attatggctt tggtggcatt ttagcagatg acatgggact tggaaaaact
    28621 ctccagacac ttgctttttt agctagtcac ctgaaatcag atagtaaagt gctcatttta
    28681 tctccatcta gtcttatcta taattggttt gatgaatgtc aaaaattcac acctcagcta
    28741 gatgttgtgg tttcttacgg acttaaacaa accagagatc aaatcatcga agaaggtcat
    28801 caaataacca taaccagcta ttcttccttt agacaggatt ttgagaccta tcaagcgttt
    28861 cactacgatt atcttatctt agacgaagct caagtgataa aaaatgcgca aactaagatt
    28921 tcacactgtt tacgtgcgtt taatacagcc aattgttttg cgctttcggg cactcctatt
    28981 gaaaataaaa tgcttgaaat ttggtccatt ttccaaattg ttttgccagg gttgctaccg
    29041 actaaaaaag agtttttaaa attaacagct gagcaagtat cacgctatat caaacccttt
    29101 gtgatgcgtc gtaaaaaaga agatgtccta ccagaattac ctgatttaat tgaaactaat
    29161 tattcaaacg agatgacaga tgaacaaaaa gctatttact tagcgcagtt aaggcagatg
    29221 caagatcaaa ttcgaaattc tagtgatgtg gatattagcc gtcaaaaaat tgagatttta
    29281 tctggtatca ctcgattgag gcaaatctgt gacactccaa gtctctttat ggattaccaa
    29341 ggcgaaagtg gtaagctaga tagtttgcga atcttattga cacaaattaa agaaaatggt
    29401 catcgggctt tgattttttc tcaatttaga gggatgctgg acttggccaa gcaagagatg
    29461 actgctctag gattgacctc ttatcaaatg acgggatcta cccctgccaa tgaacgtcaa
    29521 gaaatgacta gagcctttaa taacggttcc aaggatgctt ttttgatttc cctcaaggca
    29581 ggtggagttg gaatcaacct tacgggagca gacacagtga ttttaatcga tttatggtgg
    29641 aatcctgctg ttgaaatgca ggcaatcagt cgcgcctacc gtattggtca aaaagaaaac
    29701 gttgaagtat atcgcttaat cactcgaggg acgattgaag aaaagatttt agagcttcaa
    29761 gaaagtaagc gcaatttggt gactacagtt ttggatggca atgaaagccg agcaagtatg
    29821 tccattgaag aaataaaaga aattttgggg ctaaacactc attaatcttc cttgatttta
    29881 gtgacattaa aaacccttta aagaagatga caccaaaagc accttatata acctcgttaa
    29941 aacgcttctt ttgaaatatc tttattgata tagcgattgt catttgctag taatgattaa
    30001 aacatttaga aaaagacaag tcatagaatc atcaaggaat gctttgaaaa ataacagtat
    30061 ttaagttata atagaggatg ctacaagaag ggagaatcaa aaaaggatgg taaaaaatca
    30121 gtttccttta gttgcagatg gcattgctat tagtgatcca gcaaagcaaa tggctctgta
    30181 tgaaaatgaa gatctcatta ccaacatccg tggctattac caggacaagg agtatgatga
    30241 tattgctaga aatgaggagt ttactgctaa agcaacttct cggcaagccc cttctagtaa
    30301 gcgcttttgt agcaatgatg aaaaacacca ttatgtcaaa gaggcgcgtc aaaaagcaaa
    30361 gcaagatctc aaggaaaaaa gacaggctta tcttgccaaa gaaatggcct atgttcctaa
    30421 acaggtttct aaaaagcaac agcctgcgga ttcttctcct tctcaaaagc aagcaacaac
    30481 agaaatgagt cgttttacaa aaaagcttca tcaagacaac tatattttag ctgagttgcc
    30541 aaaagaatat aaagagccaa aaaatcttcc tcaacaagga actacaaaaa aaaataatta
    30601 cgatttttta aaatctagtc aaatttacaa taataaagaa atgagacaac aacgagaaaa
    30661 aacaattgcg caagagctta atcttagtag gtttgaggat cttccttaat aaatctactc
    30721 agcgtatgca gatgacaaag gagttaagat gtcaaaaacg tatcatttta tcggaattaa
    30781 agggtcagga atgagtgcct tggcccttat gttgcatcaa atggggcata tggtgcaagg
    30841 tagtgatgtt gaaaaatact atttcactca aagaggattg gaacaagcgg gcatcactat
    30901 cttacctttt agcgaggaca acattacgcc agatatggaa cttatcgttg ggaatgcctt
    30961 tcgtgaaaac aacaaagaag tggcctatgc tttgagacac cagattcctt tcaaacgtta
    31021 tcatgacttt ttaggtgatt ttatgaaatc atttatcagt tttgcagtag caggtgctca
    31081 tggtaaaact tctacaacgg gtttattgtc acatgtcttg aaaaatatca cagacacatc
    31141 ttatttaatt ggtgatggta ctgggcgtgg gtctgctaat gcgcagtatt ttgtttttga
    31201 atcagacgaa tacgaacgcc attttatgcc ttatcaccca gaatactcta tcattactaa
    31261 tattgatttt gaccatcctg attatttcac aggaatcgct gatgtgcgaa acgctttcaa
    31321 cgattatgct aagcaggtca agaaagcttt gtttgtttat ggtgaagatg acgaactaaa
    31381 aaagatcgaa gcacctgcac ctatttacta ttatggtttt gaagagggca atgattttat
    31441 cgcttacgac attacgcgta ctacgaacgg atcggacttt aaggtaaaac accaaggaga
    31501 ggtcattggt cagtttcacg tacctgctta tggaaaacat aacattttaa acgctacagc
    31561 agtaattgca aacttgtttg tagccggcat tgatatggct ctagtggcag accatcttaa
    31621 aactttttca ggtgtgaaac gtcgttttac agagaaaatt atcaatgaca ctattattat
    31681 tgatgacttt gctcatcatc caaccgaaat tgtggcaaca attgatgcgg ctagacaaaa
    31741 atacccaagt aaagaaattg tagcaatatt ccagccacat acttttactc gcactattgc
    31801 cttattagag gattttgctt gtgctttaaa tgaagctgac agtgtttatt tagcccagat
    31861 ttatggttct gcacgtgaag tagataaagg tgaagttaag gttgaagatt tggctgctaa
    31921 gattatcaaa ccatcacaag tagtaacggt ggaaaatgtc tctcctcttc ttgatcacga
    31981 taatgctgtt tatgttttta tgggagctgg agatattcag ctatatgaac attcttttga
    32041 ggaattactt gcaaatttaa ctaaaaataa ccaataacat gtcctgcctt aggcaggttt
    32101 tctcattcta aaggagtttg atatgttgat tagacaggtt caaggatccg atttggaagt
    32161 tattgctacc attgaaagtg acaatttttc accacaagaa gcaacgacaa gagcagttct
    32221 tgaagagcgc atacggctga taccagatac ttttttagtg gcacttatcg atcaggaaat
    32281 tgttggctat atcgaaggtc cagttgtcac tactcctatt ttggaggatt ctttgttcca
    32341 cggagtgact aaaaatccta aaactggagg ctatattgct attactagtt tgtccatagc
    32401 taaacatttt cagcaacaag gggttgggac agctttgttg gcggcactaa aagatttagt
    32461 agtagcgcag caaagaacag gtcttatttt gacttgtcat gattacttga tttcctatta
    32521 tgaaatgaat gggtttatta accaaggaat ttcagagtct caacatggtg gaaccctttg
    32581 gtaccaaatg atttggaaac tttagaatca cagctgattc aactgttggt ttgttaaaaa
    32641 taagtaacaa atgcatcatt taattgcaat taggatactt ttaagttata atggcggttg
    32701 attatattta ggaggattgg ctttgaccga ttttaaggat aaagaccaac aagatcagca
    32761 gcgaagcttt aaagagcaga ttcttgctga gttggaaaaa gcaaatcaaa tcagaaaaga
    32821 aaaagaggaa gaactttttc aaaaagagtt ggaagctaaa gaagcagcta ggagaacggc
    32881 ccagctatat gctgaatata aaagacaaga tgcttttcaa aaagagtcta tagcacataa
    32941 caataagaca gccaaacact ttcaagctat aaaagatgcg gtaatgactt cagaagcgat
    33001 taaaccgact ttactttctg aaaaagaaaa ctcatcttta aaaacgacaa gtaagagagt
    33061 cgtgcaggca aatgagcttc aagagactgc ctctaaagaa tctcaagtac cgttaactat
    33121 tgagaaaggt cattcagtga gacgaaaatt aagcaaacgc caacagactg agcgagctgc
    33181 taaaaagatt tcaaccgttt tgattagctc tattattata acccttttgg ctgttactct
    33241 agcaggagca ggctatgttt atagtgcttt aaatcctgtt gataaaaata gtgatgcctt
    33301 tgttcaagtt gagataccat ctgggtcagg caataaattg attggtcaaa ttcttcaaaa
    33361 aaaaggttta atcaagaata gcactgtttt tagtttttat acaaaattta aaaactttac
    33421 aaattttcag agcgggtatt acaatctgca aaaaagtatg agtctagaag aaattgctag
    33481 tgctttacaa gaaggtggta cagcagaacc taccaagcca tctcttggga agatcttgat
    33541 tccagaagga tacacgatta aacaaatagc taaagctgtt gagcataata gcaagggaaa
    33601 gaccaaaaaa gctaaaacac cttttaacga gaaggatttt ttggatttag tcacggatga
    33661 ggcttttatt caagatatgg taaaaagata tccaaaatta ttagcaacta tcccaactaa
    33721 agaaaaagct atttaccgtt tggaaggtta ccttttccca gcaacctata actattacaa
    33781 agaaactact atgagagaac ttgtagagga catgctggca gctatggatg ctactttggt
    33841 accctattat gataaaattg ctgctagtgg taagacagtc aacgaggtat tgaccttggc
    33901 ctctttggtt gaaaaagaag gttcaacaga cgatgacaga cgtcaaattg caagtgtctt
    33961 ttataaccgc cttaatagcg gaatggcact acaatctaat atagctattt tgtatgcgat
    34021 ggggaaactt ggtgagaaaa caaccttggc tgaggatgct actattgaca ccaccattaa
    34081 ttctccttat aatatttata ccaatacagg tctgatgcct ggtccagttg ctagctcggg
    34141 ggtttctgca attgaagcaa ccctaaatcc agcctcaacg gattatttat actttgtggc
    34201 caatgtccat actggtgaag tttactatgc aaaaacattt gaagagcact ctgcaaatgt
    34261 tgaaaaatat gtgaatagtc aaattcagta aacacaaaca tggtgcttaa gcaccatgtt
    34321 tgtgtttctg attcgttcaa aaaagaaaag agagaaaaca attatggcag aaaaaacgta
    34381 tccgatgacc ctaacggaaa aagaacaact tgaaaaagaa cttgaagaat taaaacttgt
    34441 gcgtcgtcca gaaatagtgg agcgtattaa aattgcacgt tcgtatggag atctttcaga
    34501 gaactctgaa tacgatgccg caaaagatga gcaagctttt gttgaaggtc aaatttcaac
    34561 gcttgaaact aagattcgct atgctgaaat cattgacagt gatgctgttg caaaagatga
    34621 agtcgctatc ggaaaaacag ttatcgttca agaagttgga acaacagata aagataccta
    34681 tcatattgta ggtgctgctg gagcagatat cttctcagga aaaatttcaa atgaaagccc
    34741 gattgctcaa gctttgattg gtaaaaaaac aggtgacaag gttagaattg aatcaccagc
    34801 agctacttat gatgttgaaa tcatcagcgt tgaaaagaca aattaatcag atgaagccat
    34861 tatttgccta acccctaagt gttttggttg ctaatggctt ttctagtatc ttcaaatgag
    34921 gttgactgtt aggaaggtca agtattaatc gcattgatta tgagccaaga ggactataga
    34981 tcaaagatcg ttttcgatgg ttatttaata ccaaaagaaa agaccagcac cttaatgtac
    35041 tgaccccaaa aagttggaca ctatatttta agtataggaa gtgtataatc taaggaaact
    35101 gacactaatg attgaccgtt ttgcaagact ttattaatga tttcttgctt tattttaaat
    35161 gaataagtct gatacgtttc cttccttaac actatcgact ccataatgac ccatcagtca
    35221 aacggtatat ctcaaacgac tacggtttac tccaaattga ttggctagtt gaggccaaga
    35281 aacacctgat ttttttaatg ctaaatttct agcttatctt catagcttaa tttcatacaa
    35341 aaacacccca atcgttagat ttttttgata tgtccccttt cactagatga gtccagtaaa
    35401 agggggcata tcgttttttg tctaactttt ggagtgcagt tcataattgt gctaggtttt
    35461 ttgtctttct taacgctttc gctgttttcc agcattacga ttggatttta tttttttagg
    35521 caagttagcc tgttccatgt tttgtgaagg cgtaacatcc ttacgagaag aagttgattg
    35581 gtatgcttta ggcggggttt tagcgtattc ttctttaatt tgcttatgca atcgaggttt
    35641 taagaggtag gttgtgatta actgttgaat aatactaaag aaaccaccaa ctagccagta
    35701 aagaccaaca ccagcaggga gtgagaagga catgaagatc atcatgatag gcatggtgta
    35761 catcatcgtc ttcatttgct cacgttgttc ttctgaaacg gccatcattg ataaccatga
    35821 ttggaagaag taaagagcag cgataattgc tgttaacact aaactacggc taccaagatc
    35881 aatgcccata aaggtacttg ttgatactcc tttagtgtat tgagcggcaa aatacatggc
    35941 agaaaagaat ggcatctgga tgagaagagg tagacatcca atacctccaa gagggttaat
    36001 cccatgagca cgctgagcag ccatcaattc tgtttgggca gccatttttt cttcctgact
    36061 acttgcctgt ttgatacgtt tgttgattgg ttcaaaaaca ggtttcaaga aggtcatttt
    36121 ctcagattga taacttgctt tccaagattg atatagacct agtggtaaga taagtgttct
    36181 aacaataatg gttacgatga tgatagccag tccataacct agtccagcat tgtttgcaaa
    36241 gtaatcgata aagtatgaca tgggttttcc aagaaattcc caaatcatac ctttgggatt
    36301 tccgtgagcg tctcttccca cacagcctgt caaggtgaat agaattgaca gtgctagtcc
    36361 tgaaaagagg atgcgattta atgttagttt caatgtgttt atcctttaat tttaatatac
    36421 ttatctattt tacagttttt ttcagaaatt cacaatagtt ctgaaggccg atttttaatt
    36481 gcctatttga aagtcctgaa agtcttcaaa attagccatg gtgacatcca cataagtgac
    36541 ttttgcccat ttggatggtc ctttacgaac ttcttgaata aatgtggcta ttttatctga
    36601 atcttttgat tgggccagaa tttcaacggt cccatcgttg ttattccaga cacgaccata
    36661 aatatctcct atatctagag ctaaagtatg ggtagcgtat cgaaaaccaa caccttgtac
    36721 acgtccagaa acaattaaac gtactttttg cataagaagg gcctccttgc ttttattata
    36781 acacatactt agcaggaaat ctctttagcc aattgtctac ttcctgtcac ttttactaaa
    36841 gacaagaata caaaaatgag atagttagta gtactaacag taaaagaggt ttgtctattt
    36901 taaaaatagt atcaaaaaaa ggtcttttag gtttaaaaca ttgaactgcc cccaaattga
    36961 ccatctaaga agttgatgct ttcaaatgct gtcgcgtatg gtataatagg cgcatggtta
    37021 ttacatcaaa agcaaatcaa ctaattaagc aaacaaaaaa attattgcaa aaaaagcatc
    37081 gaaaacagtc ctatttgatt gagggttggc acctttttga agaagcccaa aaatcaggac
    37141 aagtttttcg ccacatcttt gttttagagg aaatggtgga gcgtctagca ggtgagcaag
    37201 aactcgttat tgttagccca caagtgctca aggagttgac cgactctcct agtccacaag
    37261 gcattgttgc tgaggtggag atacctaagt tagcctttcc atcagattac aaagggaaat
    37321 atttggtttt agaggacgtc caagacccag gaaatcttgg gaccatcatt cgtacagcag
    37381 acgctgcacg gtttaatggg gtctttcttt ctgaaaaatc agcagatatt tacaaccaaa
    37441 aaaccctacg ttccatgcaa ggtagccatt ttcatttacc aatttggcga acagatgtct
    37501 atcagctttg tcgagagctc caagagtata aaactcccat cctagcaaca actctgtcaa
    37561 agaaatctgt tgattataaa agcctcacat atcatgaaag gttggctttg gtgttgggaa
    37621 atgaaggcca gggcattagt gctgaaatgg tagccctagc agaccaactg gttcatatta
    37681 caatgcctgg tcaggcggaa agtttgaatg ttgccgtagc agcaggaatc ctcattttca
    37741 gcttgattta agctaatatg atataataac caagtgaggt aattatgtta tgcattatac
    37801 agaagataaa gaatatatgg aacacgtcgg tcatttgatc gctcatcctc gctttcaaaa
    37861 attgagtcat attgttcagc accaacattc aacgcgtctt gaacattcta tcaatgtttc
    37921 ttattcaagt tataaattag ccaagcgatt tggttgggat gctaaaagta cagccagagg
    37981 gggcttactt catgatttct tttattatga ttggcgcgtg accaagttta ataagggtca
    38041 tgcctgggtt catcctcgta ttgctgtacg aaatgcgaaa aagttaacag aactcaataa
    38101 aaaagaagag gatatcattc taaaacacat gtggggagcg accattgctt ttccgcgtta
    38161 caaggaaagt tatattgtga caatggtaga taaatactgg gctgtcaagg aagcagtgac
    38221 gcctttaaga caaaaatggt ctaatcgacg gtttcttcgc cgcaagaccc tccaaagtca
    38281 taatcgttaa gtaaaggagt tattatgaac gatcacgtta tttatacaca atcagatgtg
    38341 ggattaaatc agttttttgc taaaatttat agtctagtgg gaatgggagt gggtttatct
    38401 gcttttgttt cttatttgat gctttatcca tttagagaaa atttaatctc tattcttgtt
    38461 aatcagccga tgatttacta tggtgctgcg attattgaac ttattttagt ttttgtagcc
    38521 agtggtgcag cacgaaaaaa cacaccagct gcattgccca tttttcttat ctattctgcg
    38581 ctaaatggct ttaccctaag ctttattatt gtggcatacg ctcaaacgac agtttttcaa
    38641 gcatttcttt cttcagcagc tgtgtttttt gccatgtcaa tcattggtgt caagactaaa
    38701 cgggatatgt caggtcttag aaaggctatg tttgctgctt tgattggtgt tgttgtggct
    38761 agtctgatta atctttttat tggtagtggg atgatgagtt atgtcattag tgtgatttcc
    38821 gtgctaattt tctcaggtct catcgcatca gataatcaaa tgattaagcg cgtttatcaa
    38881 gcaacaaatg gccaggttgg tgatggctgg gctgttgcta tggccttaag cttgtattta
    38941 gattttatta acttatttat cagccttctt cgtatttttg gaagaaatga ttaacattaa
    39001 aaagtgagta taactactca ctttttaatg ttaacaggat aagtaaactg taaggaagaa
    39061 attcgagata gatataagat gaggctgcta aaagacctag tgttaatttg taaactcttt
    39121 ctttttttgg tatactatta aggattaaat acgaggagaa tatagataga tatgtcaaca
    39181 gctatttgga ttttattact tattgttgcc cttggggtag gtgtttttgg tgggattttt
    39241 attgcccgta aacaaattga aaaagaaatt ggtgaacacc cacgtttaac accagaagct
    39301 atccgtgaaa tgatgagcca gatggggcaa aaaccaagtg aagcaaaaat ccaacaaact
    39361 tatcgtaata tcatcaaaca atcaaaagca gccgtatcca aaggtaaaaa ataaaagcta
    39421 attgttatag gggaaacctt tgtgatagtt agaagtgaac agtctttgat ctcaatgttc
    39481 agtagcactt gtcttatcag ttagatttgt caactgttca gggtttaaaa agaaactcag
    39541 ttggctattt ccaactgagt ttttcatatc gtcagtaagg aagtaaacat aatggataca
    39601 agaccaattg ggtttttaga ttctggtgtg ggaggtctga ccgtcgtttg tgaattgatt
    39661 cgtcagctcc ctcatgagaa gattgtatat attggtgatt cagcaagagc cccctatggt
    39721 cctagaccca aaaaacaaat taaggagtat acttgggagc tagtcaattt tttgctgact
    39781 caaaatgtta aaatgattgt ttttgcatgc aataccgcaa cagcggtggc ttgggaagaa
    39841 gtaaaagcaa ctttagatat tcctgtttta ggggttgtct taccgggggc aagcgcagct
    39901 attaaatcaa cgacaaaagg ccaggttggg gtcatcggaa ccccaatgac agtggcttca
    39961 gacatttatc gcaaaaaaat ccagctatta gcaccatctg ttcaagtaag gagtcttgct
    40021 tgcccgaagt ttgtaccgat tgtggaatca aatgaaatgt gttcgagtat agctaaaaaa
    40081 atagtttatg acagtctatc accattagtc ggtaaaatag atacccttgt actaggatgt
    40141 actcactatc ccttgttacg accaattatc caaaatgtta tggggccatc tgttaagctg
    40201 attgacagtg gagcagaatg cgtccgagat atctctgtct tattaaacta ttttgacatt
    40261 aacggtaact atcatcaaaa agctgtcgaa caccgctttt ttacaacagc aaatcctgag
    40321 atttttcaag aaattgcctc gatttggctg aaacaaaaaa taaatgtgga gcatgtcacc
    40381 ttatgagtga aaaaatttac gaatacaaag atgaaaataa ctggtttatc ggaaagatga
    40441 ctggtcataa tttaatatcg ggctggggag tcaaacacag gacaatcaaa aaaatagatg
    40501 accttttaga cggtattgcc gcaacgttag attgggaaaa tcctaaaggt tacgatgttt
    40561 cggtggtgcg ttatcagtct cctttatctc tcatcacctt tattatcgat atgattaacc
    40621 aagaaaccca gcgtgagatt aaggtgattc cccatgcagg cacgatttta ttaatggaaa
    40681 atgcgaaact gcttgcagtt tatctcccag aaggtggagt ttcaacggct acattttttg
    40741 cgactagtga acagggattt ggggatacta ttttaatcgc tacacgaaac gagggaaaaa
    40801 ccaaagagtt ccgcaatctg tttggccagc taggttatcg tgtggaaaat ctcaatgatt
    40861 atccagaatt gccagaagtg gcagaaactg gtactacttt tgaagaaaat gctcgcttga
    40921 aagcagaaac gatttcacac ctcacaggaa aaatggtatt agcagacgat tcaggactaa
    40981 aagttgatgc cttgggtgat ttacctggag tttggtcagc tcgtttctca ggaccagatg
    41041 ccacagatgc caagaataat gccaaactct tacacgaatt agctatggtg tttgaccaaa
    41101 agaagcgctc agctcaattt catacgactt tggtagtggc tgctcccaat aaagatagtt
    41161 tggttgtgga agccgagtgg ccaggctata ttgctacgca gcctaaggga gaaaatggtt
    41221 ttgggtatga ccctgtcttt atcgtcggag agactgggcg tcatgctgca gaattagagg
    41281 ctgaccaaaa gaatcagttg tcgcatagag gtcaagcagt tcgaaaatta atggaggtct
    41341 ttccagcatg gcaagcaaaa caatcatagt aatgagtgac tctcatggtg accgagatat
    41401 cgttcaagcc attaaagaca agtatcttgg tcaagttgat gctattttcc ataatgggga
    41461 ttctgaatta aacagctcag atcctatttg ggctggtatt tatgtcgttg gcggtaattg
    41521 tgactatgat acaggttacc ctgatcgttt agtaactcaa ttaggcacag ttacgattgc
    41581 ccagacacat ggtcacttgt accatattaa tttcacttgg gataaactgg actactttgc
    41641 tcaagaagta gcagcagata tttgtctata tggacaccta caccgtccag ctgcttggca
    41701 agttgggcaa atcctcttta tgaatcccgg atcagtaaca caacctcgcg gagaaattaa
    41761 cgagaagtta tatgctcgtg ttgaactaac tgatactcaa attaaagttg attactttac
    41821 aagagatcat aaactttacc catcactgtc taaggaattt aaacgatgat cgcaaaagaa
    41881 tttgaaacgt ttttaatgag tcatttagat aattatctta tcccggaaca agacttggct
    41941 atttttatcg acacacataa tgcagaccat gtgatgttac tattggtgag caatggtttt
    42001 tctagagttc ctgttatcac acgggagaaa aaatatgtgg gaaccattag catctcagat
    42061 attatgatgt accaatctaa aaggcagctg acagattggg aaatgagtca aacagatatt
    42121 ggcgagatgg ttaataccaa aattgaaacc attagcatta cttctagcct aacagaaatt
    42181 atgcacaagt taattgattt cccattctta ccggttgtag atagagcgaa tcgctttgtt
    42241 gggattatta cgcgaaaatc tatattaaag gctgtcaaca gtcttttaca tgattttaca
    42301 gatgattaca cgattataaa aaaatgaaga gttatattga accttttatt gctagcaagg
    42361 ctttatctca aaatagtcaa aaagcttatc gatacgattt gcaacagttt tgtcaactgg
    42421 ttggtgaacg tgtcaatcaa gacaaactat tactttatca aaatagcata gctaacctaa
    42481 gtttatctgc aaaaaaacgc aaattatcaa cagctaatca attcttatat tacttgtatc
    42541 aaataaagta tttaaatagc tattttcgat taacagatac catgaaagtg atgcggactg
    42601 agaagcagca agctgctatt attaatactg atattttcta tcaaaaaacc ccttttgtgt
    42661 gggggcaatt aatcagctta ttaatattgg agctgggttt aactccaagt gaagtagctg
    42721 gtattgaagt agctaacttg gatttaagtt ttcaaatgtt gacgctaaag actaaaaaag
    42781 gtgtgcgtgt attacctttg tcgcaaatac taatcccttt tttagaacaa caactcgttg
    42841 gcaaagaagt ctatcttttt gaacatcgag gcatcccttt ttcaagacaa tggtttttta
    42901 atcacctaaa aacctttgtt cgaagtattg gttatgaagg attgactgct caaaaattac
    42961 gagagcaatt tattttgaaa gaaaaactag ctggtaaatc gataatagaa cttagcgata
    43021 ttcttgggct gaaaagccct gtgaccttag aaaaatacta caaatcataa tggatataaa
    43081 acttaaagat tttgaaggtc ctcttgattt actcttgcac ttggtatcac agtacaaagt
    43141 tgacatctac gaggttccta ttgttgaggt tattgagcag taccttaatt atattgaaac
    43201 cttacaggta atgaaacttg aagtggctgg tgactacatg ctgatggcaa gtcagctcat
    43261 gttaatcaaa agtagaaggc tattaccaaa ggtggtagaa cacatcgaag aagaagattt
    43321 agaacaagat ctgttagaaa agatcgaaga atatagtcgc tttaaagcag ttagtcaagc
    43381 gttagcgaag caacatgacc aaagggcaaa atggtattca aaacctaaac aagaattaat
    43441 ttttgaagat gctatcttac aagaagataa aacggtgatg gatctatttc tagctttttc
    43501 aaacataatg gcagctaaaa gagcagtttt aaaaaacaac catacagtca tcgagcgtga
    43561 tgattataag attgaagaca tgatggcttc tattaaacag cgactggaaa aagaaagcgt
    43621 tatcagctta tcagcgattt ttgaggaatg ccaaacatta aatgaagtta tcagtatatt
    43681 tttagctagt ctagaattga ttaagcttca cgtggtattt gtagagcagc tctctaattt
    43741 tggggctatc atactacgaa aggagaagaa atgacgtatt tgtcacagat agaagcgctg
    43801 ctatttgttg caggtgaaga agggttaagt ttgcgacatc tagcgtctat gttatcatta
    43861 acgccaacag ctcttcaaca gcaattagaa aaactctctc aaaaatatga aaaagatcaa
    43921 cattctagtc tttgtttgat agaaacagct aatacctaca ggctagtaac taaagaaggt
    43981 tttgcagaac tcttgcgtgc ttatgccaaa acaccaatga accaaagtct atctcgtgcg
    44041 agtttagagg tcttgtctat tgttgcatac aaacaaccta ttacacgaat agaaattgat
    44101 gacattcgag gggtaaactc cagtggagct ttgagtaaat tattggcatt tgatctcatt
    44161 agagaagctg gcaaaaaaga tgtggttggg cgtcctcatt tgtatgcgac aacagattat
    44221 tttctggact atatgggaat taatcattta gacgaattga ttgaagtatc tgccgttgaa
    44281 ccggcagatg aagagattgc tctttttagg acacaagact gagttttgct tgtcatcaaa
    44341 tagcaaatga cgtttacaaa aggatttgtt ttaaggcgtt ttagttgaaa aaagccttaa
    44401 actaaggaca acaaaaagtt gctcaaaaga aagaagaata taatgcgaat taacaaatac
    44461 attgcccatg cgggtattgc cagtcgacgt aaggctgaag aattgattaa gcaaggctta
    44521 gtaaccttaa atggtcaggt tattacggat ttagcaacca ctgtaaagtc gggagacgtg
    44581 gttgaaatag aaggaagtcc tatttacaac gaggaaaagg tttactattt gcttaataaa
    44641 cctcgtggcg ctatctcaag tgtgtcagat gacaaaggcc gtaaaacggt actggattta
    44701 ctacctcagg ttaaagaacg catatatcct gttggacgat tggattggga cacatcaggg
    44761 gtccttattt taacgaatga tggtgatttt acagatacta tgattcatcc tagaaatgaa
    44821 atagacaagg tttatctggc gcgtgtcaaa ggaattgcaa cgaaagaaaa tcttcgtccc
    44881 ttaactcgag gaattgttat tgatggtaaa aagaccaaac cagctcgcta caatattgtt
    44941 catgtagaag ctgataagaa tcgatcgatc gtagaattga ctatccatga agggcgaaac
    45001 catcaggtta aaaaaatgtt tgagtctgtg gggcttttgg ttgataaatt atctcgtaca
    45061 cgttttggga ccgtcgactt aaagggacta agaccaggag aagcgagacg cttaaataaa
    45121 aaagaaataa gtcaactgca taacttagct aatacgaaaa aatgatgaaa aaactattaa
    45181 tagtatctgt taaagcttat caaaaataca tttctccttt atctcctcct agttgtcgct
    45241 acaagccaac ctgttcagct tatatgttaa ctgctattga aaaacatggt actaagggaa
    45301 tactaatggg gatagcaaga atattaagat gtcacccttt tgttgctggt ggtgtcgatc
    45361 ctgttccaga agattttagc ctaatgagaa ataaaaacac gtcaaaaaac gctgaaaagg
    45421 catgacttta tcaaaaaatg gcttgacatt gatagctgaa gtgttataat ggaaaataag
    45481 cattcgttgg tttaaatcaa acctgttatg atttaagtta gcgagtcacc atcaaccaca
    45541 ttgtttgctg agcatgactc cgagcagtgt ggttttttaa attaaaaaga gtaaatgaga
    45601 ttatgacgac aaaagaactt atcaacaaaa acgacaaagt aaaaaaggct cgcaatcata
    45661 ttgtcctgtt tcaaccccaa attccacaaa atactggtaa tattgctaga acatgtgctg
    45721 caactaatgc acctttacac attattaaac ccatgggatt tcctattgat gaccgcaaaa
    45781 tgaagcgtgc cggcttggat tactgggaca agttagaact gcatttttat gatcatttag
    45841 aacagtttat caatcaatgt cacggacagc ttcacctgat tagcaagttt gcagttaata
    45901 attattctca agctacttat gctgatggcg attcccatta tttcttgttt ggacgagaag
    45961 atacaggcct gccagaagat tttatgcgag aacatgctga aaaagcactt cgtattccga
    46021 tgaatgatga gcatgtacgg agtttaaatg tctcaaatac ggtttgtatg gtgatttatg
    46081 aagcccttag acaacagggc tttcaagggt tagagttaaa gcatacttac gaacacgata
    46141 aactaaaata atggactttt taaaagcgtc agtttttggc aatatgcgtt gtcagtagct
    46201 gacgctttta aaaatttagt caaagctatt gctatctagg tttaaatctg ctatgctaga
    46261 agtgtcttca gggcagggtg tgattcccga ccggcggtga ctagtaacta gaagtccgcg
    46321 agcgcaagct gatgtggtgt aactccacaa ccgacagtat agtctggatg agagaagacc
    46381 gggctttttg tgtaggctta ttttagctac acaataacga cggaacttct ttcaatttga
    46441 aaaaattgga ggaatttttt aatgtcaaaa acacataaaa tgattatgat tggtatactt
    46501 tctgcgatat catttctatt gatgctagtt agctttgcca ttattccagg cgcagctttt
    46561 ttaaaaattg aatttagtat tattcctgtc ctatttggtt taatgattat ggacttaaag
    46621 agtgcttact tgattttgtt attgaggtcc ttattgaaac tctttttgaa caatcgtggg
    46681 gttaatgatt ttattggtct cccaatgaat attatcgcta tcgctttatt tgtgacggct
    46741 tttgccttag tttggaaccg tcaaaaaacg cttagtcaat atgtatttgc tagcttacta
    46801 ggcacagggt tattaacatt tggcatggtt gttctcaatt atacttttgc cattccttta
    46861 tatgctatat ttgcaaatat tgatatcaga gcttatattg gtgtcactaa gtatatgatg
    46921 actatggtta ttccgtttaa tcttgttgaa gggttgatat ttgcaattac cttttatttt
    46981 gtgtatattg caagtaaacc aattttagaa agatacttac actaatatga tgacaaataa
    47041 acaaactcac tttttaatag cttcttttgc attactaatc tttgttataa taggctatac
    47101 ggtcaaattt tttcctgaac gtttggcact tctagataat actattcaag cagagattag
    47161 aggcaacctt cctatagtgc tgacgcaatt ctttaggggt gttactgtat ttggaaatgt
    47221 catgacacaa attttgttag ttattgtgtc ggtcctagtt ttattcttta tgaagtggaa
    47281 aattgaagcc ttgtttatct tatcaaatgg tgccattgca gcatttttga ttacgactct
    47341 caagctcttt taccaaagac caagacctgc tattgagcat ttggtttatg ctggtggcta
    47401 ttcgtttccc agtggccatg cgatgggtag catgctgatt tttggtagcc tattgattat
    47461 ttgttatcaa aggctacatt caaaactatt acaatttgtg actagcatga tctttataat
    47521 actaatttta gtaattgggt tatctcgtat ttatctaggg gtacactacc caagtgatat
    47581 tttagcagga tttgtattag gatttgggat tttgcagttt atttatcctt tttataagca
    47641 aaaacgattt gaatggcgat ttcttttgaa acaagactaa tttttcttga gaagacatag
    47701 ggcttattta aatcatttag aataacattg gcaagcatca ccccttgatt gccagtgtta
    47761 ttttagtttt agttagatga tgtgagctga tgattagtaa atatgtttag ataaaaaacg
    47821 attaaagtgc tatgtaacgt cagaaaagac gtgatttttg ttgatctgta atcattaagt
    47881 aagctgatgt agaagtagtg aattctaatg actgagctat cttttgcata gatgactatc
    47941 ttgctagtaa tgatttgtgc tacaatagaa acatgaaaaa aagatatcag acattaaatg
    48001 agcattaccg tcaactattt ggcgcaaaaa tgtttaaagt tccgattgat gccggctttg
    48061 attgtcccaa tcgtgatgga acggtagctc atggaggatg tactttttgc acagtatcag
    48121 gttctggaga tgctattgta gcaccagatg ctccaattaa agagcaattt tataaagaaa
    48181 ttgattttat gcaccgtaaa tggcctgatg tcaatcgcta tttggtttat tttcaaaact
    48241 ttaccaatac tcatgataca gttgatgtga ttcgggatcg ttacgaacaa gctattaacg
    48301 aacctggagt tgttggcatt aatattggca cacggcctga ctgtctacca gatgatacca
    48361 ttgcttattt agcagaatta tcagaacgca tgcatgtgac agtggagcta ggcttacaga
    48421 caacttatga agaaacttct aggctaatta acagagcaca ttcttatgat ttgtataaag
    48481 aaacggtgag gcgactaagg cattacccca acattaatat tgtctcgcac ttgattaatg
    48541 gattgccaaa agaaactcat gacatgatgc ttgaaaatgt gagacgctgt gtaacagaca
    48601 atgacattca aggaattaaa ttgcatttgc tgcatttgat gaccaatact agaatgcaaa
    48661 gagattatca tgaaggacgc ttaaagttgt tgagtcaaaa ggactatgtt tcgattattt
    48721 gtgaccagct agagattatc cctaagcata ttgtgattca ccgtattaca ggagatgccc
    48781 cacgagatat gttgattggg cccatgtgga gtctaaataa gtgggaagta ttgaatgcca
    48841 ttgataaaga aatggaaaga cgaggaagct ttcagggctg taaagttgac taatttgtct
    48901 cattttgacg gatttggata ggagaaaagt gatgctaaaa cgccccattc atctctcgca
    48961 tgatttttta gcggaggttg tggataagtc tagtgtggtt gttgatgcca cgatgggtaa
    49021 tggaaatgat actgcctttt tggcacaatt agctaaaaag gtttatgctt ttgatgtgca
    49081 agaacaagct attagaaaaa caagtgagcg gttagcgcag ctaggattat tgaacgctga
    49141 gctgatttta gcgggtcatg aagcggttga tcagtatgtg acggagccgg tgcgtgcagc
    49201 gatttttaac cttggttatt tgcccagcgc agataaatct attattacct taccaaatac
    49261 cacactccaa gctttatcaa aactactaac gttattaatg gtaggtggac gtattgctat
    49321 tatggtctat tatgggcatg atggaggcag tttggaaaaa gatgctttat tagattttgt
    49381 caagcaatta gaccaaagaa aggtttctgc aatgctttat cagcctctta atcaggtgaa
    49441 taccccacct tttttaatca tgttggagaa attagcagac gtttagccct tatccctgtg
    49501 tcaagtctac tagaagttct gcgattattt cggtggaaaa agaagaaatc ccataggctt
    49561 tggctataaa tgtgatataa tgaagtcact atattatttt tttaggagtt acattaacat
    49621 ggaagaccct gtgagtcagc ccttagtgat tcaattttta ttgttagttg ttttaacctt
    49681 gttaaatgct tttttttcag ccagtgaaat ggccttagtt tctctcaatc gttctcgggt
    49741 ggaacaaaaa gcagcagacg gtgataaaaa atacgctcgt ttgttgcggg ttttagagga
    49801 acctaatcat tttttatcaa cgattcaagt tgggattacc tttattagtt tactatcagg
    49861 agcaagttta tcagcttctt tgggtaaggt gatctcaggt tggctaggta attcagcgac
    49921 tgcaaggaca gctggtacta tcatctcctt ggttttcttg acttatgtct ctattgtttt
    49981 aggagaattg tatccaaaac ggattgccat gaacctcaaa gacaagttgg cgattgtttc
    50041 agcccctatt atcattgggt tagggagact ggttagtccc tttgtatggc tcttatcagc
    50101 ttctactaat ttactgagcc gacttacccc tatgaccttt gatgatgcag atgagcaaat
    50161 gacacgtgat gaaatcgagt atatgttatc aaaaagtgag gcgacccttg atgctgaaga
    50221 aattgagatg ttgcaaggag ttttctcact tgatgaaatg atggcgcgtg aagtcatggt
    50281 tccaaggacc gatgctttca tgattgacat taacgatgat ccgcttgaaa atattcagga
    50341 aatcttaaaa caaagttttt cacgcattcc tgtttatgat gtggataaag ataaaattat
    50401 cggtctcatc cacactaagc gtctcttgga gtcaggtttc cgccagggat ttgatcagat
    50461 taacatgcga aaaatgttac aagaacctct ttttgttccc gaaaccattt ttgtagatga
    50521 tctcttacgc cagctgcgca atacccaaaa tcagatggct attttgctag atgaatatgg
    50581 tggtgtggca ggacttgtga ctttggaaga cttgcttgaa gaaatcgtcg gtgaaatcga
    50641 tgatgaaacc gataaagcag aacaatttgt tcatgagatt ggagacaata cctatattgt
    50701 tgttggtacc atgactttaa atgagtttaa tgactatttt gataccgaac tagaatcaga
    50761 tgatgtagat accattgctg gtttttattt gacaggtatc ggaaccattc caagccagga
    50821 tcaaaaagaa gcctacgaaa tagataacaa agacaaacat ttagttctaa tcaacgataa
    50881 agtcaaagat ggccgtatta cgaaattaaa attaatcctg tctaatatag aacagattat
    50941 tgaggaagac taggctccat gcctagtctt tttgatgaaa agtgttataa tgaaaatgta
    51001 aaaacgttta caagtaatga aggagatgca atgactgaga aagattatgg acaagtaaca
    51061 gggatggtgc attcgacaga aagttttggt tctgtagatg gtccaggcat tcgttttatc
    51121 attttcttgc aaggctgtaa attacgttgc caatattgcc ataatccgga tacttgggag
    51181 atggaaacca acaattcaaa aatcagaaca gtcaatgatg tcttgaaaga agcccttcag
    51241 tacaaacatt tctggggaaa aaaaggagga attaccgtat ctggtggtga agctatgctt
    51301 caaattgatt ttatcactgc cttattcatc gaagctaaaa aattaggtat ccataccaca
    51361 ctagacacct gtggctttac ctatagaccg acacctgaat accatcaggt tcttgataac
    51421 ttattggcag tgaccgattt gattttattg gacttgaaag aaattgatga aaaacaacat
    51481 aaaattgtca cgcgtcagcc taataaaaac atattgcaat ttgctaggta tttatccgac
    51541 aagcagattc ctgtctggat tcgacatgtc ttggttccag gcttgactga tattgatgat
    51601 catttgacac gattgggtga gtttgtcaaa accttgaaaa atgtcgataa atttgaagtt
    51661 ttgccttacc ataccatggg agaattcaag tggcgtgagc taggtattcc ttatcagtta
    51721 aaaggtgtta aaccaccaac taaggaacgc gttcaaaatg ctaaaaatct gatgcagacc
    51781 gaatcttaca cagaatatat gaatcggatt catcagtcat aagagctgtt atagggttga
    51841 ggtttcctca actttttaaa gtattataag cagatctttt gtaatcttcc tttgatttta
    51901 gggggtaatt ttgctaaaat aaaatgaata aacaaaatga ggtagaatga ttatgtcaaa
    51961 aattttagtt tttggtcatc aaaatcctga tacggatgct attgcatcat cttatgcttt
    52021 tgattactta tcccaaaaag cgtttggttt ggatactgaa gtcgtagctt taggaacacc
    52081 taacgaagaa acagcttttg cccttgatta ttttggtgtt gaggcaccac gtgtggtaga
    52141 gtctgctaaa gcacaagggt ctgaacaagt gattttgaca gaccacaatg aattccaaca
    52201 atccattgca gatatccgtg aggttgaggt atatggtgtg gttgatcacc accgtgtggc
    52261 taattttgaa actgcaaatc ctttatacat gcgtgtggaa ccagtaggat cagcctcatc
    52321 tattgtttac cgtatgttta aagaaaatgg catcgaggtg ccaaaagcga ttgcagggat
    52381 gctcttgtct ggtttgattt cagatacctt gttgttgaaa tctccaacaa ctcatgtgtc
    52441 tgatcacctt gtcgctgaag aattggcaga gctagcagaa gtgaacttgg aagactatgg
    52501 aatggctctt ttaaaagcag gtacaaacct tgcaagcaaa tcagaagtag aattgattgg
    52561 tattgatgcc aaaacatttg aattaaatgg caatgctgtg cgcgtggcac aagtgaacac
    52621 tgttgacatt gcagaagtct tagaacgtca agaagctatt gaagcagcca ttaaagatgc
    52681 catggctgca gaaggttatt cagattttgt tttgatgatc acggatattg ttaactcaaa
    52741 ctctgaaatt ctagctattg gagcaaacat ggacaaggtt gaagcagcct ttaacttcac
    52801 ccttgacaac aatcatgcct tcttagcagg tgccgtttct cgtaaaaaac aagtggttcc
    52861 acaattgaca gaaagttttg gagcttaatg aaaagacgct ttaaaaggac ttgatttttt
    52921 tgaccaagtc cttttgtcac tcttctatgt tataatagaa ggtatgataa cagtatttca
    52981 ttcagataaa ctcaccagac aacctttctt tcaagacctt atcaattatc tcgaccagca
    53041 tgatcacgtt atattacgag agatcaaaaa agcctttcct aatgtgacag gtattgacaa
    53101 ggccatcgaa agctatgttc aagctggcta tattagccgt gaaaataagc gttatggcat
    53161 caatcttcct ttggtgagtt ctgatcagca gctggcctta gacactatgc tttttgtgga
    53221 cacctgttca gctatgtatg aaaatatttt agcggttgtt tttgagactc agctaacaaa
    53281 ccaaaccaat cacgtgatga tcaaggaaaa gaccaacatc acgagagacg atttgaccct
    53341 ggctaattat ttttaccgtc tcaaaagagg tgagaagcca tcagctgagc agatggactt
    53401 gtatgacctc ttgggggatg tgaatcagga atatgccctt aaatatatga caactttttt
    53461 gcttaaattt acgcgcaaag accttgtgat gcaaaaacgt cctgatatat ttgtggaagc
    53521 tctggttaca cttggttacc taaaacaagt ggagcctaca acataccagc tgctaatgac
    53581 cttggataaa gaaagtttaa cctttatagc accatagaaa aaagctagga acaaggactg
    53641 ttcttagctt tttgagtgtt tttattttgt ttttgccatt aagtaaagaa aataaggggc
    53701 tccgataagc gacactaaaa tccctgtctg gatattactg ccaaccagat acactcgtcc
    53761 gactgtatct gcaacaagaa gtaggatcat tccgattaaa atgctaatgg gtattgttaa
    53821 tttatgatta ctccctacca agtatgtact aaagtgtcca gctattaagc cgataaaact
    53881 aatattacca accaaaagaa cactcaaagc acctaagcca gctgctaaga caagtatcaa
    53941 acgacgctta cggtttaaag ggagtcctag cccaatagca gtattatcag ctaatcccat
    54001 aatattaagg aaatgggctt gactataagt caatggccaa aaacacaata ataaaggagc
    54061 gatgacactc agagtaggcc agtcgtctcc tattaattgg ccgctaagcc aattgatgac
    54121 caaatcgact ttgtagcgat taatatgacc aacaagagca accattagac ttgaaagcat
    54181 ggtagtaaca gctacaccag taagaattaa ccgtgtagga tcaatttgtc cttgttttgt
    54241 caaagatagc caataaacgc taaaggttgt tacaatagca ccaagcatgg caaataaagg
    54301 caagtaatgg ctgatatgag cttgctcaaa gaaagaaaag gagaccacaa tagccaaaga
    54361 gatacctgct cctatagtaa tacctaatac accagagtca gctaagggat ttcgtgttaa
    54421 acgttgtaat aatagccctg ataaagcaag agaaccgcct cctagacaag cagctagaat
    54481 tcttggcaga cgaatgttaa taacgatgaa agatatggca tggctagatt ttcccaaaaa
    54541 cacatggata aggtccaaaa aagatagatg agattctcca agggacaaag ctaatcccat
    54601 aagacttaca agtagcagga tcaggctagt atataacccc aaaaggtgtc ggtgagattt
    54661 caatagcggc ctcctcttct tattaaccat aaaaagcatg gaaaaccaat taagctaacc
    54721 aatgccccaa gaggggtttc ataaggcgga ttgagattac gacaagcaat atcaacccat
    54781 accatgaaac tagcaccaga aactgcacaa agaggcaaaa ggtatcggta atgatgaggt
    54841 gtaaagtgtt tcataagatg aggaatgact aagccgataa aagaaatgct tccagcaatg
    54901 gctacagctg ctgatgataa aataagaacc aaaatcataa agactgcact gatcaagttg
    54961 gtcttttgcc caagagcttt tgcctgagac tcacttagac taaggacggt caggtgataa
    55021 gataatagct gggctaaaca aagactaaga ataataagag gagcaatata gccgatcatt
    55081 tgccaattga ccccgacaag acctcctgct tgccagccga taacagcatt tgccagatga
    55141 tagtaattgg taataccttg acccaatgct gatagcagta tggaaaccat agctcctgct
    55201 aagacaaggc ggagctgatg gtagcctttg ccagattgat aagaaaggcc aaagactaag
    55261 gttgctgcca ggctagaccc taacaacgaa agcagaataa tgagggaata gtgcaagtga
    55321 ggtacaaacg cataagccag taccaaggct agtcctgctc cagcattaat gcctaaaagg
    55381 ccaggctcag cgataggatt acgtgtgatt gcttgcatga tagttccaga aacagctaac
    55441 gcagagccag ttaaggtagc accaaaaagt ctcggtaatc gtatagctag taaaacattg
    55501 gctttatggc cgttttgctt tccaaataaa atagagttaa gatcctgatg tgataaagca
    55561 acggctccaa agcgcagatg acagtaaata gcaacacata agctaaaact aagtagcaca
    55621 aagataagcc aaaagatatg tgacttagtg attatctgcg ttttttttaa gcaaaaacgc
    55681 tcgagacaca aaaagggatg cttagttttc acttgataag attgcctctc gtaaagtctc
    55741 taattgatat tctaaagaaa gaggatcagt aaagtaaaaa acattggcat tgactttgat
    55801 cacatggtgt tttttcacag ctggaatgga ttgccatagc ttgctttcat atagagcaga
    55861 accagtctta tcatcttctg cagcaacgac gacataatca ccaatatagt ctggcaagac
    55921 ttcctgcgac aatgacaggt aaccttgttt aaaaacttca gtcttcactt tttcaggagc
    55981 atcataatgg aaagcttgat ggataacctc tccgccacgt ccccagtctt taccaaaaag
    56041 gtaaacgtct ttttcataaa gccccataat agtaaaggtt gctttgtcac ctgtaacggc
    56101 cttgacttct ttttcataag ctgctgtttt agttttccaa tcttttaacc atttcttggc
    56161 tttgccttct ttgttaaaga tgcggccgaa gtcagataac acttgtaaat aatcatgttt
    56221 gcggtattca atcgaaataa caggcgcaat ttctgccaat tgtttaatat tttcttctgt
    56281 agagccaaca acaatgaggt caggcttaag cgttgtaatg gcttctaaat cagttgcagc
    56341 aacttgcttt gcttttttta cagtctttgc taagatgggg tttttcttgt cataagaagt
    56401 aaccccgact agattcatat ctaatttttt gaggtaacca gtgtaagttg aagccagact
    56461 gactactcgc ttaggctgtt taggaatatc tccgtaataa gtcacaccag caatttgagg
    56521 cataggcgat aaactttttg aggcggtgtt agaatgatta gttgcttgat taccacaggc
    56581 gattaaggta atggttgtca aacagagtgt taatagtaga gttaattttt tcatgtatgc
    56641 taattctcct agaataaagt tattgaagct gataagtcag cactatagga cagttgtgga
    56701 taggatcatc aaccagtacc ggtttgattt ggaagatgtc ttgaatgata ggtgaagtca
    56761 taacatctgc tatagtacca gtataatgga tcttgccatg tttcatagca atcagatgat
    56821 ccgaatagcg ggctgaaaga ttgaggtcgt gaagaaccat aacaatagtc ttgccggcat
    56881 ccttatttag ggatttaacg agctctagga tttctagttg atgatttaaa tctaaataag
    56941 tagttggctc atctaaaaaa atagtatcag tgccttgggc taatgccatt gcaagccaaa
    57001 ccctttgacg ttgcccccca gaaagagcat caacaggttg atcagcatag gccatgacat
    57061 tggtggcttg catagcccaa tgaatgactt ttttgtcagc tggactaaga tttccaaagt
    57121 aagattgatg gggaaaacgt ccgtaagaaa ccaattcgta aacagttatg ccgttagttg
    57181 cttcttgaac ttgaggtaaa agagctagtt ttttagcaac ctctttagtt tctaatgtgg
    57241 caatgttttg cccatttaaa tacacaactc cctgttttgg tggtaataat cttgtcagtg
    57301 cttttaataa actagacttc ccacagccat tggcgccaat aatggtcgta attttacctt
    57361 caggaatata aaacgataat ttatcgatga tggtacgctg ttcataggca attgtgaggt
    57421 cttcagcact aattgttgtc atatggttgc ctcctttcta aaaagagtca aagggttgat
    57481 gaaagtgcac attaaagtat tcatctgccc attttaaaat atttgagaag tagcttattt
    57541 tctcaaaatc ttcactatta tagcatagaa aaaaggctta acaaagcctt ttttgatgtg
    57601 atttttagga tgtattaaaa aagaaatatt agtttagaat gattaaaaac aatagcgaga
    57661 atcattctaa agtaacgtca acatactcta gaggtagtgt ttggcgattg ctaaatcacc
    57721 agcataagct acttgttgtc ctttaacaat ttgataagca tctgcgcctt tcccagcgat
    57781 aatcacagca tcttttgctc cttggcaaag agacatggct ttttgaatag cttgctcacg
    57841 gtcactaata atctctaccg ggcgtgcgat atggctggca atttcctgcg aaatatcttc
    57901 tggatcctcg aaattagggt catcagcagt gagaatgacg gtgaggtttg gatgctgatg
    57961 aatcacccta ccaaaatcag ctcgtctgct ctcgccttta tttcctggtg cacctaaaat
    58021 caacattaat ttgcctgtct gatgttcttc cacaacgctg agtaattttt ctaagctgtc
    58081 accattatgg gcataatcaa caaaaacttt agcatgatta gtcatggtga ggacttccat
    58141 acggcctggg acgcgagtct tagcgatgcc tttttgaata tcagctaggc tagcacccaa
    58201 acgaaggcag gcaagtccag ctgccatagc attttcttgg ttaaaatggc caattaattg
    58261 aatgtcataa tggccagcta attgtccttt agcttcaaag gagaaagctt ggctagtggt
    58321 gatctggttg tcagacaagg gaccataaaa catatgctct tgatccgcta cctgatcagc
    58381 tagaaatgaa aaatgatcca tcccgctatt gatcacaaca gctctgctat tctccattaa
    58441 aagacgctta tgatagaaat aatcttcaaa cgttggatgc tcgattgggc caatatgatc
    58501 aggactaata tttaggaaaa ccccaacatc gaacgtaagc ccatagacac ggtcaacgag
    58561 gtaagcctga ctagaaactt ccataatcaa gtgggtcatg ccattagtca cacactcagc
    58621 catcatagca aaaagatcca agctttcagg agttgtaagt tgtgatttga aaaaggtctt
    58681 gccatctaag gtggtattca tggtagaaaa catggcaggt ttataggatt ctttcaacat
    58741 gtggtaggca aaataagcag ccgtcgtctt tcctttagta cctgtaaaag ctagtagttt
    58801 gagcttttct tgagggttgc catagaaagc catggcaatt agactcatag cttttttgat
    58861 atcagtgacc aaaacaacgg gaataccaag ctcgtaatct acctctgaaa tatagagttg
    58921 taatccgtta gtgattgctt ctttaaggta gtcagctttg aaagttgccc ctttagcaaa
    58981 aaaaagggtc ttgccatcta cttgacggct atcgtaactc aagcgctcaa aacttaagcc
    59041 ttgataatgg tagtggtatc cgtcggcatc aagaacctca cgaaaattat ggtctttttt
    59101 taaaatgtct aataattgtt caatggttat cataccctta ttttatcctt aaagttcttg
    59161 ttttacaagt cacaagcaaa agtttataat aaaactaata gaaactagga aagaatagat
    59221 atgtcgacag aaaaaaaaca actgacacaa gaagaattga tggttcaggg agcagcctgg
    59281 tccacagctg gtaatttcat tagccgactt ttgggagtgt tatacattat tccctggtat
    59341 atttggatgg ggcaatacgc gattcaagcc aacgctcttt tcaatatggg gtataatgtt
    59401 tatgcttatt ttttattgat ttcaaccaca ggactcaatg ttgcgattgc taagcaggtt
    59461 gccaagtaca attccatggg acaaactgag catagctatc aattaatccg aagtacccta
    59521 aaactcatgc ttggtctggg ccttattttt tcagccatta tgtatctggg ttctccttta
    59581 tttgcgagat tatctggtgg tgacgacaca cttgttccca ttatgcacag cctttcttta
    59641 gcagttttta tttttcctgt aatgagtgtg attcgaggca tctttcaagg ccacaataat
    59701 atcaagcctt atgcagttag tcagattgct gagcaactca ttcgggttat ctggatgctt
    59761 ttgaccacct tttttatcat gaagttgggt tctggtgatt acgcttcagc agtgactcag
    59821 tcaacttttg cagcctttat cgggatggtg gctagtatgg gtgttctggg gtactatctt
    59881 tggaaacagg gacttctagc agctattttt agtaagccag atcatactgt ttctattgat
    59941 atcaagggct tgttgcttga aaccttaaaa gaatccatcc cctttatcgt aacaggaagt
    60001 gccattcaag cctttcaatt gattgatcaa tggacttttg tcaatacgat gactcttttt
    60061 acagattata gccgttctca attgcttgtt ttatttggtt actttaacgc aaacccagcc
    60121 aaaattacaa tggtcttaat tgcagtagca gcatctattg gtggtgtagg tattgccttg
    60181 ttaactgaaa attatgtcaa aaaagacatg aaagcagctg ctcgtttaat cattaacaac
    60241 attgaaatgt tagtgatgtt tttgttacct gctcttactg gggcaattat tttagcaaga
    60301 cctctatatt ctgtttttta cggagctagc gaggagcgtg ccattcacct ctttgtggcg
    60361 gttctctttc aaaccttgct actggcgctt tacaccctct tttcaccgat gcttcaagct
    60421 ctttttgaaa atcgaaaagc gatttactac tttgcctatg gtatcttgat taagttagtt
    60481 ttacagatac cgcttattta tttgctacat gcttatggtc ctttactagc gacgacgatt
    60541 gctttagtgg tgccgattta tttgatgtat cgacgcctat atcaggttac tcattttaac
    60601 cgcaaactgt tgcaaaaacg tttattatta accttaattg aaaccttatt aatgggactg
    60661 gtcgtgtttg tggccaactg gctattgggc tatgccttta aaccgacagg ccgcttgacc
    60721 agccttcttt acctcctcat tattggtggc ttgggaatga cggtttacac ggcactcacc
    60781 ttgctgacgc atcaactgga taaattaatt ggtagcaaag ctagtcgcct tcgtcagaaa
    60841 ttaggctggc attaatataa tgacaccaag aacggtttcg tgagtgttta tcgaaatcgt
    60901 tttttcttaa tgatctcgct tagtaaaggt agctgataaa aaatcaggat ttcccaagca
    60961 aactactgat atttttggta taatgataaa agtgtaaaaa aatagaagga agtatatcaa
    61021 catgggaaaa tgtcaagtta tttcgcatcc gcttatccaa cacaaacttt caatcttacg
    61081 tcgtcaaacc acatcaacta aagattttcg tgagttggtt aatgaaattg cgatgctgat
    61141 gggatatgaa gtgtcacgcg accttccctt agaagatgtc gacatccaaa cgccagtctc
    61201 aaaaacggtc caaaaacagt tagctggtaa aaaattagct attgttccga ttcttcgtgc
    61261 tggtattggg atggttgatg gcttgttaag tttggtacca gctgcaaaag ttggccatat
    61321 cggcatgtac cgtaatgaag aaacccttga acctgttgaa tacctcgtta aactaccaga
    61381 agatattaac caacgacaaa ttttccttgt tgatccaatg ttggcaacag gtggttcggc
    61441 tatcttagca gtggattcgt tgaaaaaacg tggcgcagca aatattaagt ttgtctgttt
    61501 agttgcagca ccagaagggg tgaaaaaact tcaagaagct catccagata ttgatatctt
    61561 cacagcagca cttgatgatc atttaaatga acatggctat atcgtgccag gcttgggcga
    61621 tgctggtgat cgtttatttg ggacaaaata aaagagacaa ccatcaaata gtagcctttt
    61681 taggccaatc gttcttgatt ttgttaaaaa aatcagagag atttctcttc tttaaaggaa
    61741 aagcaagttt atgatttgat ctttattgac caaaatatta taataaggac aatcagtaaa
    61801 aaagagatga cctagtgggt tgccgtctct cacaatgacg ctactaaaaa cccttgtaga
    61861 ttggagaatg tattatgatt cctgttgtta ttgaacaaac tagccgtgga gaacgttctt
    61921 atgacattta ttcacgttta ttaaaagacc gtattatcat gttaacaggg cctgtcgaag
    61981 acaacatggc caactctgtc atagcgcagc tcttattcct tgacgcgcaa gacaacacta
    62041 aagatatcta cctatatgtc aacacaccag gtggctctgt ctcagcaggc ttggctattg
    62101 tcgataccat gaactttatc aaggccgatg tgcaaactat tgtcatgggt atggcagctt
    62161 ctatggggac agtcattgct tcatcaggaa caaaaggcaa acgctttatg ttaccaaatg
    62221 cagagtatat gatccaccag ccaatgggtg gcacaggcgg tggcacgcaa caaacggata
    62281 tggctatcgc agcagaacat ctcttaaaaa cacgtcaccg tttagaaaaa atcttagcgc
    62341 aaaatgctgg aaaaacgatt aaacaaatcc ataaagatgc tgagcgtgat tattggatga
    62401 gtgctgaaga aaccttggct tacggtttca ttgatgaaat catggaaaac aacgaactaa
    62461 aataaagagg atctctgcaa aagtattcta gaaacttcta ggatgctttt tctcttagaa
    62521 aggaaaataa tgatacagcc tactgcatta aaacagcttc aagagttaaa acgtcagttc
    62581 agatcccttt gcaaccaatt atgagatagt ttgaggatga tccttagcag ctgtgtgcac
    62641 gaagttatga cgatttcata aaggatgacc tagccagtct ttcttcgtct cttttactta
    62701 aagtgtggta taatcagatt atgctagcca caactaaaaa atgcattgcc attaaaggtg
    62761 ttgtagatcg gcttatccta gatctcataa caatgctgta gtaccgccct taccttgcta
    62821 ctaaaggcgc tgttgaagca caaattgact tgcaaaggat cttgactgat aatatgtccg
    62881 gtggaatcgc caaagcagca aaaagaccaa gacccttatt tggtctctac caaaatataa
    62941 tagaaaagga tttagaatgt ttcaaaaaca agaacgtatt ggactcgtcg tttacctgta
    63001 ttataaccga gatgccagaa agttatcaaa atttggtgat ttatattacc attccaagcg
    63061 ctctcgttac ctcattattt atattaataa aaatgattta gacacaaaat tagaagaaat
    63121 gagacgtttg aaatgtgtta aagacattag accatcagct tttgatgata ttgaccgcca
    63181 atttgtaggt aaccttcatc gcgacgaaac aaacaaccat caaaagggtt aacaaccccc
    63241 tagttactga ttagcgtttc agatttagtt agcttattaa agtaagaagg ttttgacaga
    63301 tgctcacact acttcaagac aatgagacaa ctagagcatt agtgaataac tgagttgacg
    63361 gtcacttctt taataagaac ggataggatt ggtcctaaaa tagagcactg caaagatatg
    63421 ccagtgcttt ttagctcatt ttttgataaa atagaactac taaaaagtga aggaaataag
    63481 atgatcacag gaaaactcat aaccgttgaa ggtccagatg gcgcagggaa aacgactgtt
    63541 ttagagcaac tcattccact gttaaaacaa aaagtggctc aggagatctt gacaacaaga
    63601 gagcctggag gtgttgccat ttcagaatac attagggaac ttattttaga catcaaccat
    63661 actgctatgg accctaaaac agaactctta ctttatattg cggctcgaag gcagcatttg
    63721 gtggaaaagg tactaccagc tcttgaagca ggccagttgg tttttattga tcgtttcatc
    63781 gatagttcag tagcttatca aggtgcggga cgcggtttga tcaaagcaga cattcagtgg
    63841 ctcaacgagt tcgcaacaga tggtttagag cctgacttga ccctttattt tgatgttcct
    63901 tctgaaattg gtttagcacg gattaacgcg aaccaacaaa gagaagtcaa tcgtttagat
    63961 ttggaaacaa tagagataca tcaacgagta cgaaaaggat acctagcctt agctaaggag
    64021 catccaaaac gtattgtcac aattgatgcg actaaaccat tgaaagaagt tgtctctgta
    64081 gctttggaac atgtcttagc cttgctttta gcctaggata agggagggta ggaatggatt
    64141 tagcgcaaaa agctcctaac gtttatcaag catttcagac gattttaaag aaagaccgtc
    64201 tgaatcatgc ttatcttttt tcgggtgatt ttgctaatga agaaatggct ctttttttag
    64261 ctaaggtcat cttttgtgaa cagaaaaagg atcagacgcc ctgcgggcat tgtcgctctt
    64321 gtcaattgat tgaacaagga gattttgccg atgtgacggt attggaacca acagggcaag
    64381 tgattaaaac ggatgtggtc aaagaaatga tggctaactt ttctcagaca ggatatgaaa
    64441 acaaacgaca agtttttatc attaaggatt gtgacaaaat gcatgtcaat gccgctaata
    64501 gcttgctaaa gtatattgag gagcctcagg gagaagctta catattttta ttgaccaatg
    64561 atgataacaa agtgcttccg accattaaaa gtcggacaca ggtttttcag tttcctaaaa
    64621 acgaagccta tctttaccaa ttggcacaag aaaagggatt attaaaccat caggctaagc
    64681 tagtagccaa acttgccaca aacaccagtc atctagaacg tctgttgcaa acgagcaagc
    64741 ttttagaact gataactcaa gcagagcgtt ttgtatctat ttggctgaaa gatcagttgc
    64801 aggcatattt agcgttgaat cgtctggtac agttagcaac tgaaaaagaa gaacaagatt
    64861 tagttttgac ccttttgacc ttgctcttgg caagagagcg tgcgcaaacg cctttgacac
    64921 aattggaggc tgtctatcag gctaggctca tgtggcagag caatgttaat tttcaaaaca
    64981 cattagaata tatggtgatg tcagaataag tgcaattgga attcgttatg gggaaacgaa
    65041 gcttgtcaaa agacttgccc gtagcgacca aagtagcggc gcataggggc aaaaaagctt
    65101 ttgaagaaaa tactgccctt gcaacagatt tgatgaaaga agtatcacga ttaatgatac
    65161 aaaatcaact tgaaatgacg tttattaata gtgtctttcc cttagatcag catgttgtcc
    65221 taattccctt ttcagcagaa gagcacatgg atttttacaa ctgttaaaag atttagcggc
    65281 cggttttagg tcaagaagtg agctgcccca gattaacagc caagaagatt tcattttcta
    65341 tggaggctat ggaccgtgtg gcaggccact gtgctgcttt cgtttttggg aaaatttctg
    65401 acagtatcta ttaaaatact aaaaaatcaa gggttatcat tgactttggg taaagcaaca
    65461 agcccttatg accgtttgct ttgctgtctc tatgatgaag gtggctttta ccaataaagc
    65521 aagaaaaaat tccctgatta tggtaccata gtagagacaa gtgatggccc tgcaacagta
    65581 gcagccttga tatatttaca gatcccatta aggtgcggtt aaaagaccag ttgaccttag
    65641 tcacttatgc tttagaggag gttaaagtag gtgaataaaa aagaattatt cgatgctttt
    65701 gatggatttt cccaaaattt aatggttact ttagctgaaa ttgaagccat gaaaaaacaa
    65761 gtccaatcac tagtagaaga aaacacgatt cttcgcctag aaaatacaaa actacgggaa
    65821 cgtttgagtc acctagaaca tgaaacggta gctaaaaatc cttccaaaca aaggaaggat
    65881 cacttagagg gaatttatga tgaagggttt catatctgca attttttcta tggacaacgt
    65941 cgtgaaaatg atgaagaatg tatgttttgc agagaattat tagatagaaa gtaagggcat
    66001 gcaggttcaa aaaagtttta aagacaaaaa aacaagcgga accttgtatt tggttccaac
    66061 cccaattggc aatctgcagg acatgacctt tagagcagtg gcaacgttaa aagaggttga
    66121 ttttatttgt gcagaagaca caagaaacac aggtcttttg ctaaaacact ttgacattgc
    66181 taccaagcaa atcagctttc atgagcacaa ctcctatgag aagattcctg atttaattga
    66241 tttattaata tcaggacggt cactagctca ggtatctgat gcaggaatgc catcgatttc
    66301 tgatcctggg catgatttgg tcaaggctgc tattgatagt gatatcgcag tcgttgcttt
    66361 accaggtgcc tcagcaggga ttacagcttt gattgctagt ggactggctc ctcaacccca
    66421 tgttttttat gggtttttac ccagaaaagc agggcaacaa aaggctttct ttgaggacaa
    66481 acaccattac acagaaacac aaatgttttg tgaatcaccc tatcgcatca aagataccct
    66541 gaccaatatg ttggcttgtt atggtgatcg tcaagtggtg cttgttagag aattaaccaa
    66601 gctttttgag gagtaccaac gggggtcgat ttcagaaatc ttgtcctacc ttgaggaaac
    66661 acccctaaaa ggggagtgtc tgctgattgt ggctggagcc caagtagaca gtgagattga
    66721 gctgacagct gatgttgact tagtgtctct agtgcaaaaa gaaatccaag caggagccaa
    66781 gccaaatcag gctattaaaa caattgctaa agcttaccag gtaaatcgcc aagagcttta
    66841 ccaacaattt catgacttat aagtcatcgt agattaggag aaaaacaaat gacagaagat
    66901 caagcaacta tccttatttt aggagtatac ggaatcatat tggctgtatt ctcattatca
    66961 gctttattat gccttatcgc taactggcga ctctttaaaa gagcaggtta caaaggatgg
    67021 catagtctca ttcctttcta tgcaggtttt gtcaaacaca aaatcacttt tggagaagat
    67081 aataaatggt tttactttat tggttgggtc attgctattt attattacta tgtgcacttt
    67141 tgctatgtcc gtgcttttgg tggaccaaag ggtctagcag tatttggctt gtttttccca
    67201 ggccttgctt ctttgatagt ggcttttgga aaaacttata ccacacaaga atgccaccct
    67261 gtgccacatc ttttaaacta agagaaaaaa gaccatcaat tggatttatt gatggtcttt
    67321 taggtgttta aatgatttta gtcccgtgaa caatggccgt tccagtgagt tgactcaagt
    67381 tttggcaatt ctcagcagtg acgcctcctc caatcatgat ttcaatgcgt ttattggcat
    67441 aggtcacaag acttttaagc tgttccacat tatctgtaat aggagtagct tcaggggagc
    67501 catgagttag cacacgcaca aagccataat caatcagttg atcaagcgct tggtgctggt
    67561 ggtcagtcgg aatatggtca aaagccatgt ggaaaaccag tggcaagcct tgtgtagcag
    67621 gcagtaattg ctcgatagcg tcggtatcca gttgattttc tgtggtcagc aagcctaaga
    67681 ctagcgcatc tgagccagct tcaacagctt ttaagatatc ttcttccata gcttttagtt
    67741 cgaggtcgtt atagacaaaa tcgccaccgc gaggtcgaat catggtcgct acgctaatct
    67801 ttttatcgtg taagagctga caggcttctt tgatgacgcc ataagatggt gttgttcccc
    67861 cgacagctag gttatcacag agttccacac gactgacttg accagcatca agggttggca
    67921 gtagtgtgag gttctcagca caaaattctt taatcatttt tagatctcct ttatcactaa
    67981 tattatagca cgaatgaagc tagtcatcag gaaacatttt tgtcaaatca tggagattat
    68041 gctatactca ctagtattaa aagtaggcca aaacagcagc aaatactttg aaaaaagatt
    68101 gctatgttct acggcaatat cagtctttac caacgaactc tcaagaagaa aagaaagaca
    68161 aagcttagca ttttaaaaaa gccccccttt ttttgtgaaa tgatgaccaa aaacgggcgc
    68221 ctcacgccta aaacagttac cctaaaggag aacaaatgat tacgatttac caatacccaa
    68281 aatgtagtac ctgtcaaaga gccatggctg aattaaagca actggttagt gactttgaag
    68341 tcattgacat caaagctaat ccacccaaag ctcaggacct caaacattgg atggaaacat
    68401 ctggttatac catcaaaaat ttctttaata ccagtggtaa cagctaccgc gaattgggac
    68461 ttaaagataa aatagaccag cttagccttg ataaagctgc tgaactctta gccacagatg
    68521 gtatgctgat taaacggcct attctgatta aggacggtaa agtcctacaa gttggctatc
    68581 gcaagccata tcaagagttg gatttaggat aatgcgacaa agtctcaaaa aaggacaagg
    68641 caacattata acgccttgtc cttttttggg atctgttttt agacattaga aatcaatatc
    68701 tagtaaaatt ggcgtatggt cttggcgttc cccagaagaa atcatttcag aacgcttaac
    68761 cttatccaca agtcggtttg aagctagcca atagtcaatt ctccaaccgg tattattgat
    68821 tttgctggtt ttgctacgtt gtgcccacca ggtataaaca tgaggaatat cgccgtgcaa
    68881 gtgacgaaaa gtatctgtaa agcctcttgc taataggtta gtaaagcctt gacgttcttc
    68941 gtcggtaaaa ccaggggaac gtcgattgct gcttggattt gccaaatcaa tctctttgtg
    69001 ggcaacgttg taatctcccg tagccaaaac aggcttttga gcatccagtt cagtcaagta
    69061 atcagcgtat ttgtggtccc agatttgacg gtcatctaac cgtctaaggc catcgccggc
    69121 attaggcgtg taaacctgtg tgacgaaaaa gtcttcaaat tctagggtaa tgatacggcc
    69181 ctcagcatcc attgttgttg gggcatcaat ttctggaaaa gtaatgacag ggtttaacgt
    69241 gtttttgtaa aggaacatgg tgccagcata gcctttccta gcaggctcaa ctgaagaacg
    69301 ccacacatgc aaatagtttg gaaagtaact aagtaaggcc tcgatatgtt ttttggtagg
    69361 ccccttagca gataatttgg tttcttgaat ggcaataata tccgcatctt gagcgactaa
    69421 agtgtctaaa acagcgcgtg ataaaagcgc acgaggggac tctcctgtga gagcagcatt
    69481 taaggaatca atgttccatg aaatcagttt catttggcat ctctttctaa cagatagtct
    69541 tgttgttatt gtaacaaaaa acgaaacgat aagcgacttt gggcacctag cccccataaa
    69601 acagtctagc caaatgaagc atagcagcgt aagaacaaga caaggaggtg atcagtgagc
    69661 atatcgtttg acagttaaga gtaggattac tataatagaa gcataaatgt aagcgctaac
    69721 aaaataaaaa atataggaga atgtcaatgg cacaaaaaac agtcatcacc gaggaaacaa
    69781 ccgattttgt tatggatttc aaaacaagta gcgctgaggg aaatgttgat tttattaacg
    69841 tttttgacct tgagaaaatg gcacaacagg tcatccctaa aggagccttt ggttatattg
    69901 ctagtggtgc tggtgatacc tttaccctcc atgaaaatat tcgctcattt aatcataaat
    69961 taattgtccc tcactccctc aaaggggttg aaaatccgtc aacagagatt acgtttgatg
    70021 gtgatcactt aacctctcct cttattttag cacctgtagc ggctcataag ctggccaatg
    70081 aacaaggaga agtagcgtct gccaaaggat tgaaggaatt tggaagtatc tacaccacta
    70141 gttcctactc aacaactgac ctgccagaaa tcagtgctgc cttaggtggg acaccccatt
    70201 ggtttcaatt ttattacagt aaagacgatg gcattaatcg taatattatg gatcgtgtca
    70261 aagcacaagg ttgcaaagct atcgttttga cagcagatgc aacagttgga ggaaaccgcg
    70321 aagttgatag gcgaaacggc tttgtttttc cggtcggtat gccaattgtt caagaatatt
    70381 tacctgatgg tgcaggtaaa acaatggatt atgtctataa atcagctaaa caagcgctta
    70441 cctcaaaaga tattgaatat atcgcaacct actcaggcct gcctgtttat gtcaaaggac
    70501 cacagtgtgc tgaggatacc ttgcgggcat tggacgcagg agcatcaggt atctgggtaa
    70561 ccaatcatgg tggccgtcaa ttagatggtg gtccagctgc ttttgattcc ttacaagaag
    70621 tcgctgaagc agttgatcac aaagttccta ttgtctttga ctcaggtata agacggggtc
    70681 aacatatttt caaagctctt gcttcaggtg ctgaccttgt tgccttgggg cgtccagcga
    70741 tttacggctt ggctatggga ggaagcattg gtactcgtca ggtctttgaa aagttaaatg
    70801 acgagttaaa aatggtcatg caactggctg ggacacaaac tatccaagat gttaaagcct
    70861 ttaaccttcg ccataatccg tatgattcat cgattccatt tgatcaaaat gcgctacgct
    70921 tagattagaa cagacaaaaa cctctgctat catgtcacaa atagtagagg ttttacactg
    70981 caaaaagagg tatgaaaatc caataacata gttacaaggc tttcgtttaa cacccccact
    71041 aatagattaa aatgaaagac ttcttacatt aatagaagtt tctgttgctt ttctcagaaa
    71101 aatgtggtta aataatcaaa tattattaac gaaaaatgag ttaatgatta acattaaatt
    71161 ggttttaatt aaaacattta ggagggtatc aggtggagaa aaagcaacgt ttttccctta
    71221 gaaaatacaa atcaggaacg ttttcggtct taataggaag cgttttcttg atgatgatga
    71281 caacaacagt agcagcagat gagctaacca caacgagtga accaacaatc acgaatcacg
    71341 ctcaacaaca agcgcaacat ctcaccaata cagagttgag ctcagctgaa tcaaaacctc
    71401 aagacacatc acaaatcact cccaagacaa atcgtgaaaa agagcaatca caagatctag
    71461 tctctgagcc aaccacaact gagctagctg acacagatgc agcatcaatg gctaatacag
    71521 gtcctgatgc gactcaaaaa agcgcttctt taccgccagt caatacagat gttcacgatt
    71581 gggtaaaaac caaaggagct tgggacaagg gatacaaagg acaaggcaag gttgtcgcag
    71641 ttattgacac agggatcgat ccggcccatc aaagcatgcg catcagtgat gtatcaactg
    71701 ctaaagtaaa atcaaaagaa gacatgctag cacgccaaaa agccgccggt attaattatg
    71761 ggagttggat aaatgataaa gttgtttttg cacataatta tgtggaaaat agcgataata
    71821 tcaaagaaaa tcaattcgag gattttgatg aggactggga aaactttgag tttgatgcag
    71881 aggcagagcc aaaagccatc aaaaaacaca agatctatcg tccccaatca acccaggcac
    71941 cgaaagaaac tgttatcaaa acagaagaaa cagatggttc acatgatatt gactggacac
    72001 aaacagacga tgacaccaaa tacgagtcac acggtatgca tgtgacaggt attgtagccg
    72061 gtaatagcaa agaagccgct gctactggag aacgcttttt aggaattgca ccagaggccc
    72121 aagtcatgtt catgcgtgtt tttgccaacg acgtcatggg atcagctgaa tcactcttta
    72181 tcaaagctat cgaagatgcc gtggctttag gagcagatgt gatcaacctg agtcttggaa
    72241 ccgctaatgg ggcacagctt agtggcagca agcctctaat ggaagcaatt gaaaaagcta
    72301 aaaaagccgg tgtatcagtt gttgtagcag caggaaatga gcgcgtctat ggatctgacc
    72361 atgatgatcc attggcaaca aatccagact atggtttggt cggttctccc tcaacaggtc
    72421 gaacaccaac atcagtggca gctataaaca gtaagtgggt gattcaacgt ctaatgacgg
    72481 tcaaagaatt agaaaaccgt gccgatttaa accatggtaa agccatctat tcagagtctg
    72541 tcgactttaa aaacataaaa gatagcctag gttatgataa atcgcatcaa tttgcttatg
    72601 tcaaagagtc aactgatgcg ggttataacg cacaagacgt taaaggtaaa attgctttaa
    72661 ttgaacgtga tcccaataaa acctatgacg aaatgattgc tttggctaag aaacatggag
    72721 ccctgggagt acttattttt aataacaaac ctggtcaatc aaaccgctca atgcgcctaa
    72781 catctaatgg gatgggaata ccatctgctt tcatatcgca cgaatttggt aaggccatgt
    72841 cccaattaaa tggcaatggt acaggaagtt tagagtttga cagtgtggtc tcaaaagcac
    72901 cgagtcaaaa aggcaatgaa atgaatcatt tttcaaattg gggcctaact tctgatggct
    72961 atttaaaacc tgacattact gcaccaggtg gcgatatcta ctctacctat aacgataacc
    73021 actatggtag ccaaacagga acaagtatgg cctctcctca gattgctggc gccagccttt
    73081 tggtcaaaca atacctagaa aagactcagc caaacttgcc aaaagaaaaa attgctgata
    73141 tcgttaagaa cctattgatg agcaatgctc aaattcatgt taatccagag acaaaaacga
    73201 ccacctcacc gcgtcagcaa ggggcaggat tacttaatat tgacggagct gtcactagcg
    73261 gcctttatgt gacaggaaaa gacaactatg gcagtatatc attaggcaac atcacagata
    73321 cgatgacgtt tgatgtgact gttcacaacc taagcaataa agccaaaaca ttacgttatg
    73381 acacagaatt gctaacagat catgtagacc cacaaaaggg ccgcttcact ttgacttctc
    73441 gctccttaaa aacgtaccaa ggaggagaag ttacagtccc agccaatgga aaagtgactg
    73501 taagggttac catggatgtc tcacagttca caaaagagct aacaaaacag atgccaaatg
    73561 gttactatct agaaggtttt gtccgcttta gagatagtca agatgaccaa ctaaatagag
    73621 taaacattcc ttttgttggt tttaaaggac aatttgaaaa cttagcagtt gcagaagagt
    73681 ccatttacag gttaaaatct caaggcaaaa ccggttttta ctttgatgaa tcaggtccaa
    73741 aagacgatat ctatgtcggt aaacacttta caggactcgt cactcttggt tcagagacca
    73801 atgtgtcaac caaaacgatt tctgacaacg gtctacacac acttggtacc tttaaaaatg
    73861 cagatggcaa atttatctta gagaaaaatg cccaaggaaa ccctgtctta gccatttctc
    73921 caaatggtga taacaaccaa gattttgcag ccttcaaagg tgttttcttg agaaaatatc
    73981 aaggcttaaa agcaagtgtc taccatgcta gtgacaagga acacaaaaat ccactgtggg
    74041 tcagcccaga aagctttaaa ggagataaaa actttaatag tgacattaga tttgcaaaat
    74101 caacgaccct gttaggcaca gcgttttccg gaaaatcgtt aacaggagct gaattaccag
    74161 atgggtatta tcattatgta gtgtcttatt acccagatgt ggtcggtgcc aaacgtcaag
    74221 aaatgacatt tgacatgatt ttagaccgac aaaaaccggt actatcacaa gcaacatttg
    74281 atcctgaaac aaaccgattc aaaccagaac ccctaaaaga ccgtggatta gctggtgttc
    74341 gcaaagacag tgtcttttat ctagaaagaa aagacaacaa gccttataca gttacgataa
    74401 acgatagcta caaatatgtc tcagtagaag acaataaaac atttgtggag cgacaagctg
    74461 atggcagctt tatcttgccg cttgataaag caaaattagg ggatttctat tacatggtcg
    74521 aggattttgc agggaacgtg gccattgcta agttaggaga tcacctacca caaacattag
    74581 gtaaaacacc aattaaactt aagcttacag acggtaatta tcagaccaaa gaaacgctta
    74641 aagataatct tgaaatgaca cagtctgaca caggtctagt cacaaatcaa gcccagctag
    74701 cagtggtgca ccgcaatcag ccgcaaagcc agctaacaaa gatgaatcag gatttcttta
    74761 tctcaccaaa cgaagatggg aataaagact tcgtggcctt taaaggcttg aaaaataatg
    74821 tatataatga cttaacggtt aacgtatacg ctaaagatga ccaccaaaaa caaaccccta
    74881 tctggtctag tcaagcaggc gctagtgcat cagctattga aagtacagcc tggtatggca
    74941 taacagcccg aggaagcaag gtgatgccag gtgattatca gtatgttgtg acttatcgtg
    75001 acgaacatgg taaagaacat caaaagcagt acaccatatc tgtgaatgac aaaaaaccaa
    75061 tgatcactca gggacgtttt gataccatta atggcgttga ccactttact cctgacaaga
    75121 caaaagccct tggctcatca ggcattgtcc gcgaagaagt cttttacttg gccaagaaaa
    75181 atggccgtaa atttgatgtg acagaaggta aagatggtat cacagttagt gacaataagg
    75241 tgtatatccc taaaaatcca gatggttctt acaccatttc aaaaagagat ggtgtcacac
    75301 tgtcagatta ttactacctt gtcgaagata gagctggtaa tgtgtctttt gctaccttgc
    75361 gtgacctaaa agcggtcgga aaagacaaag cagtagttaa ctttggatta gacttaccgg
    75421 tccctgaaga caaacaaata gtgaacttta cttaccttgt gcgggatgca gatggtaaac
    75481 cgattgaaaa cctagagtat tataataact caggtaacag tcttatcttg ccatacggca
    75541 aatacacggt cgaattgttg acctatgata ccaatgcagc caaactagag tcagataaaa
    75601 tcgtttcctt taccttatca gctgataata acttccaaca aattaccttt aagatgacga
    75661 tgttagcaac ttctcaaata actgcccact ttgatcatct tttgccagaa ggcagtcgcg
    75721 ttagccttaa aacagctcaa ggtcagctga tcccgcttga acagtccttg tatgtgccta
    75781 aagcttatgg caaaaccgtt caagaaggca cttacgaagt tgttgtcagc ctgcctaaag
    75841 gctaccgtat cgaaggcaac acaaaggtga ataccctacc aaatgaagtg cacgaactat
    75901 cattacgcct tgtcaaagta ggagatgcct cagattcaac tggcgatcat aaggttatgt
    75961 caaaaaataa ttcacaggct ttgacagcct ctgccacacc aaccaagaca acgacctcag
    76021 caacagcaaa agccctacca tcagcgggtg aaaaaatggg tctcaagttg cgcatagtag
    76081 gtcttgtgtt actcggactt acttgcgtct ttagccgaaa aaaatcaacc aaagattgat
    76141 aacaaaacgc aaagagacaa caaatcatcc cttttaacag tcggatcttt ctttgagatt
    76201 gagctggcag ctgatcattt cttaacaaaa gttaaagagt tgagtaaagt aaggaacaga
    76261 cataaacacc ataaaagcaa gccagtttgg cttgctttta tggtgttatt gtcgtgtgct
    76321 acgatgacta aaaaagaaca acgaacaatg acctcgaatc accaaaagga cttgatttga
    76381 tagcttccct atgctatact aagcctattc tttcaagaag gactcctttt gtggaaaaga
    76441 ctgaaaaaaa ggacactaat ctatccaaaa actccagatg agtagctgca aacggatgcc
    76501 tttgctgtga tcaaggtgat aaagcagact ggcttgtcac tacctgagca ggtatcaaaa
    76561 aaagaagctt ttggctttgt cattcaacat actgagcttt agtattttag aacggagaca
    76621 cccccagttt tgtactcaaa aagcataaac agctctgctg atgcgacatc cgatttctac
    76681 gtccgcagtg agccaaacca gctgctgttt gctatggtaa aagtggcgcc aatcgggatt
    76741 tttgagaccc taggctcaaa aataaggcat agaattccaa aggaagttgc tgccatgagc
    76801 acaacctaag aaaaactatc ccaaaagact ttttcagcaa tttgaaatac tgaatttcag
    76861 tattttttct tttgtaacta agagcaatga atgaggtaaa aaaggcaaca atgtcaaaaa
    76921 agaaacgaaa acactatcag gtttatgagg gattacgctg tgctatgacg ctttgtttta
    76981 tcagtggcta tgtcaatgcc tttacctata tgacacaagg caaacgtttt gcaggtgttc
    77041 agacaggcaa ccttttgtca tttgccattc gcttgtcaga acagcaactg aaggaggcac
    77101 tgcaattttt acttcccatg atagttttta tgcttgggca gtcctttact tatttcatgc
    77161 accgctgggc cactaaaaag ggactccact ggtacctctt atcaagcgtt atgttaacag
    77221 gacttgcttt tggaacggcc ctattcacgc cttttcttcc ttccaatgtt acggtagcag
    77281 ctttagcctt ttttgcctct attcaggttg atacgtttaa aaccttacga ggagctagct
    77341 atgctaatgt gatgatgaca ggaaatatca aaaatgccgc ctatttacta accaaaggct
    77401 tgtacgaaaa aaatcacgaa ctaacacata tcggacgcaa caccttaata gtcatcttgg
    77461 cttttgctgt tggggtggtt tgttcgacgt tgctttgcat agcttatggc gagtatgctt
    77521 tgatgcctat tttaatgcct ttactctatg tcaattacct gttggctcag gaattttatc
    77581 acattcaaac caaaatcaaa ccgattaaaa gaacttaacg gacttgtgga gaaagaaagt
    77641 tcatttaggg taagttttta cttaccctcc gttgatttgc tggttttgct gccccttaaa
    77701 atatgatata atagaccatt gatagctgtt acttaacaga aggctgataa aaaaggttcc
    77761 attagccttg agggttgaat ttaaacagga aaaaacgaaa tcctacacta tgcatctcaa
    77821 tcgtactttc atttgagtat ggttctgaaa ggaaactatg atgaaaaaac cattttacat
    77881 tacgacaccc atttattacc catctgggaa attacacatt ggctctgctt atacaactat
    77941 tgcttgtgat gtcttggcac gctacaagcg cttgatgggc catgaggtct tttaccttac
    78001 aggacttgat gagcacggac aaaagattca aaccaaggca aaagaagctg gcattacacc
    78061 tcaaacctat gttgataaca tggcaaagga tgtcaaagcc ctttggcaat tgctagatat
    78121 ttcctatgac acatttatcc ggacaacgga cgattaccac gaagaggtcg ttgctgctgt
    78181 ctttgaaaaa ttgctggcgc aagatgacat ttaccttggc gaatactctg gttggtattc
    78241 tgtctctgat gaggaatttt tcactgaaag ccaattaaaa gaagtcttta gagatgaaga
    78301 cggtcaggtt attggaggga ttgccccatc aggtcatgag gtcgagtggg tctctgaaga
    78361 atcctatttc ctacgcctta gcaaatacgc tgatcgtctt gtggccttct ttaaagagcg
    78421 acctgacttt atccaaccag acggtcgtat gaatgaaatg gtgaaaaact ttatcgagcc
    78481 aggcctagaa gatttggctg ttagccgtac tacctttaca tggggtgtac ctgttccatc
    78541 agacccaaaa cacgtggttt atgtctggat tgatgccctc ttaaactacg cgacagccct
    78601 tggttatggt caagctaatc acgctaactt tgacaaattc tggaatggaa cggttttcca
    78661 catggttgga aaagatatct tgcgtttcca cagtatctac tggccgatct tactcatgat
    78721 gcttgattta ccaatgccag accgcttaat tgctcatggt tggtttgtca tgaaagacgg
    78781 taaaatgtct aaatcaaaag gcaatgtggt ctatccagaa atgttagtgg agcgctttgg
    78841 acttgatcct cttcgttatt acctcatgcg ttctttgcca gtgggttcag acgggacctt
    78901 tacccctgaa gattatgtgg gtcgtatcaa ctatgaattg gccaacgatc ttggtaattt
    78961 attgaatcgt accgttgcga tgattaacaa gtattttgac ggcacggtgc cagcttatgt
    79021 tgacaatgga actgcctttg atgctgactt aagtcaactg attgatgctc agctagcaga
    79081 ctaccataag cacatggaag ctgtagacta cccacgcgcc ttggaggctg tttggaccat
    79141 cattgctcgt accaacaaat acatcgatga aaccgctcct tgggtgctcg ctaaagaaga
    79201 tggagacaaa gctcaactag ccagtgtcat ggcacacttg gcagctagct tgcgcgtggt
    79261 cgctcatgtg atccaaccct ttatgatgga aacatcagct gctatcatgg cccagcttgg
    79321 cttagcgcct gtttctgact tgtcaacact tgctctagca gattttcctg ccaatacaaa
    79381 ggtcgttgcc aaaggcacac cgattttccc acgtcttgac atggaagctg agattgacta
    79441 catcaaagct caaatgggtg acagctcagc tatttcccaa gaaaaagaat gggtccctga
    79501 agaggttgcg ctcaaatctg aaaaagacgt catcacattt gaaacctttg atgctgtgga
    79561 aatccgtgtg gcagaagtca aggaagtgtc aaaagtggaa ggttcagaaa aattgctgcg
    79621 ctttagagta gatgcaggag acgggcaaga ccgtcaaatc ttgtcaggta ttgccaaatg
    79681 ctaccccaac gaacaagaat tagtgggcaa aaaactacaa attgttgcta acctgaaacc
    79741 gcgtaaaatg atgaaacaat acatcagcca aggcatgatt ttatcagcag agcatggaga
    79801 tcagctaacg gtcttaaccg ttgatccctc tgttccaaat ggaagtatca ttggctgatg
    79861 ctgacctatt attcaaaaaa cctaagcaag aatatgtgct taggtttttt tgattgcctt
    79921 caagaaagac gaataacgag atgggtgata tgacatcaaa agcataacta tcctaggacc
    79981 tgtcctagta agattgctgt gcttttgaca agtgaacaga gaggtcttaa actatatctt
    80041 gtcataaaaa agattgcaaa acactatatc ttgtgttatt atggttttta taaaagttaa
    80101 gcatgcttaa ctttagccaa acaaaagagg acactagagc gtgtcccaca agacagttga
    80161 gcccttcgct tttttagtag agtaggagtg ctcaagtcaa aaagagacat cccatcaaac
    80221 cattgctgtt tagcaggtct ttttgtgttg ctcaaaaaaa caattcctgt ctgtttggcg
    80281 tctagtgatg acttaggctt agcgctacta gacttttgtt tgaaaaatac ctcaagcctt
    80341 gaaggagaca aatgacccaa cattattatg aacgttcgca atccccaatt gaatacgccc
    80401 tatctgaaac acaaaaacag ttgcgctcca tcaattggaa ttaccttaat gatgacaaag
    80461 atttggaagt gtggaaccgt gtcactcaaa atttttggtt gcctgaaaag gttcctgttt
    80521 ctaatgattt aaattcttgg cgctccttgg gtgaggattg gcaacagctc atcacaagga
    80581 cctacactgg gttgacctta ctagatacag tacaagcaac ggttggtgat gtggcacaaa
    80641 ttcagcattc acaaactgac cacgaacaag tcatctatac gaactttgcc tttatggtgg
    80701 ggatccatgc ccgctcttac gggacgattt tttcgaccct ttgcagtagc gagcaaatcg
    80761 aagaagcaca tgaatgggtg gtctcaacac agagcttgca agaccgtgcc cgtgtcttga
    80821 ttccttacta tacgggtgat gaccctttga aatcaaaagt agcagcagct atgatgccag
    80881 gatttttgct gtatggcggc ttttaccttc ctttttacct atcagcacgt ggtaaaatgc
    80941 caaacacatc tgatatcatc cgcctgattt tacgcgacaa agttattcac aactattaca
    81001 gcggttacaa ataccaacaa aaagtagcac gtcttagccc agaaaaacag gctgaaatga
    81061 aggcctttgt ctttgacctg ctctatgaac tcatcgacct tgaaaaagct tacttgagag
    81121 aactgtatgc aggctttgat ttggcagaag atgctatccg ttttagcctt tataacgctg
    81181 gaaaattcct tcaaaattta ggttatgact cgcccttcac agatgaagaa acgcgcgttt
    81241 caccagaagt atttgctcag ctatcagcgc gtgcagacga aaaccatgac tttttctcag
    81301 gcaatggctc atcttatgtg atggggatca ccgaagaaac aacagatgac gattgggagt
    81361 tttaagaaat ggcagagctg attattgtgt atttttcatc taagtccaat aacacccatc
    81421 gcttcgtcca aaaattaggc ctgcctgctc agcgcatacc agtagataat aggccacttg
    81481 aagtttcaac ccattacctt ttgattgtgc ctacctatgc agctggtggc tcagatgcca
    81541 aaggagccgt tcctaaacaa gtgattcgtt ttttgaataa tcctaacaat cgtaaacatt
    81601 gtaagggagt gatctcttca ggaaatacca attttggcga tacctttgcc ttagcaggcc
    81661 ctatcatttc tcaaaaattg caggtcccct tattacacca atttgaacta ttaggcactg
    81721 ctacagatgt caaaaaggta caggcgattt ttgcccgctt aaagcatcat acacacgaca
    81781 agcaaaaaca aactaacaac ctgattacag aaaggacaca cccatgtcac aaaccaatgc
    81841 gtcatacctc tcattaaatg cactgactcg ttttaaaaaa ccagacggca gctaccattt
    81901 tgatagcgat aaggaagctg ttaggcgcta cttggaagaa catgtctctc ccaatcaaat
    81961 ggcttttaac tcactagaag ataagttagc ttacctcatc aatgaagggt attatgagca
    82021 ggccattttt gatgcctatc ctaacgacct tatcaaggat gcctttcatt atgcctatca
    82081 acaaggctat cgctttttaa atctcatggg cgctatgaaa ttttaccagt cctatgcctt
    82141 aaaaaccttg gacggtaagc agtatctaga aacatttgaa gaccgtgctg tgatgaatgc
    82201 actcttttta gctgatggag atcaaacctt tgtctttgac gtgattgatg ccatcttgca
    82261 ccgacgcttt caaccagcta ccccaacgtt tttaaatgcc ggaaaaaaac gccgtggcga
    82321 atacatttcg tgctaccttc ttcgtgtcga agacaatatg gaatctatct ctcgcgccat
    82381 tagcaccagc ttgcaactct caaaaagagg aggcggagtc gccttgtgcc tcaccaacct
    82441 cagagaaatc ggagcaccga taaaagggat tgaaaatcag gcaacaggca tcgttcctgt
    82501 catgaaacta ctagaggact ctttttccta tgccaatcaa ctaggtcagc gccaaggagc
    82561 aggtgcggtt taccttcatg cccatcatcc tgaggtcctg acctttttag acaccaaacg
    82621 tgaaaatgcc gatgagaaaa ttcgcattaa gtccctagca ttgggacttg tgatcccaga
    82681 tattaccttc cagttagcca aagaaaacaa agacatggct ctcttttcac cctatgatat
    82741 caagtgtgcc tatggcaagg acatgtcaga catctccatc acagaggaat acgataaact
    82801 gctagccaat ccagccatca aaaagactta catcagtgct agaaagctct ttcagttaat
    82861 tgcagagcta cattttgagt caggctaccc ttacctcttg tttgatgaca cggtcaataa
    82921 gcgcaaccct catgccaaaa aaggcagaat cgtcatgtct aacctgtgtt ctgaaatcgc
    82981 tcaagtcagc accccaagca ctttcaaaga agatttgagt tttgaaacca ttggagaaga
    83041 tatctgctgt aatttagggt ctatcaatat tgcccaggct atggcagatg cgccacactt
    83101 tgaacagctc atcacaacga gcatcagagc acttgatcgt gtctctagag tgtctgacct
    83161 gaattgtgcg ccttctgttg aggcaggcaa tgcagccaac catgcagtag gattaggcgt
    83221 catgaaccta catgggtttt tggcaaccaa ccacatctac tatgatacaa aagaagccgt
    83281 tgactttaca gatctgtttt tccatgccat ggcctatcat gcttttaaag cctcttgcca
    83341 attagccaaa gaaaaaggcg cttttgcagg attttcgtta tcaacctatg cagatggcac
    83401 ttattttgcc aagtatttgc aagaagatgc caagccacaa acagccaagg ttgccacatt
    83461 gttgcaagat tacggcttca cattgccaac ggtggcggat tggcaagccc tagtagcaga
    83521 tatcaagcag tttggcctag ccaatgcgca cttgctagcg gttgctccga caggctccat
    83581 cagctactta tcatcatgca ctccgagtct acaaccagtc gttgctcctg ttgaggtccg
    83641 aaaagaaggt agccttggca ggatttacgt ccctgcctat cagattgacc aggctaacta
    83701 tgcttactat gaacgtggtg cctatgaggt cggcccaaaa gccatcatcg acgttgtcgc
    83761 tgctgcccaa aaacacgttg accaagccat ctcattgacc ctgtttatga ccgatcaagc
    83821 gaccacacgt gacctgaacc gctcctatat ccaagctttt aagcaaaact gtgcatcgat
    83881 ctattatgtg cgagtgaggc aagacgtcct agcaggcagc gaacagtatg acgaggatag
    83941 tcttgtgaca gctcctggag ctagtgatga gaccaccaca gagtgtcaaa gctgtatgat
    84001 ctaacagcta ctagaaagct ctcgtgtcac ctatcacatg cataggatca gtgcgctcga
    84061 cctttcaaga caagcaagca tcagctcttg cttgtctttt tttggcctca aagcccgtta
    84121 gtctactgct gtgtgaggct ttttttgagc atcagaacgt caaaaaaaaa aggacatgga
    84181 gtcctttttt ggtgatcggt gttgaggccg tcacaaactg cccttgaaat acgcttctat
    84241 gtggagcttt ttgtggtcct gtgacacgta agctccaacg acctccagct gacagcctct
    84301 tggaaacaag agctcaacct ctgaaggcac agccgaataa ggctcgacaa aggctgcttt
    84361 ggcccctttt ttgacacaga tgcgcacctc caccggtcga tgggtcatag cgccgttttt
    84421 caaggctgtc gtgctcataa aactgtgctt agtgtagcgt gtgccaagct tgatcttaca
    84481 aaggatatga gggtcaaact gatcgttacg gtagtaagac gtgagatcag cgtgtgaaac
    84541 accgatatca cgcaaaaacg tctcgtacac atagcggtat accacaatgt tccacgggat
    84601 gactagccgg tgagtcgcag catcgagctg ggccacctga tcccttagct caggcgtgag
    84661 ttggctgagc tcacccttgg tcttgtctag actggtattg ataagggctg cctgctgaca
    84721 ggtataagca gccatcgcct cttgctcagt ccttgggtag acaagaccct tgccccagcg
    84781 ctttttaatt agtgtctcag cgcctttttg atccgaaaag gtaaaataag caggcgtccc
    84841 ctcacaaacc gcccgctcat agtactcaca gacaaaaagc tcgaccaagc cctcagtttg
    84901 ccagatcaga ctaaaacagc taagaagaag gatcatagcg agttgatagc gcttttttag
    84961 catagttccc cctgacacca gcccaaaagg ctgacccttc ccctagacct tttggctagc
    85021 tcttgacacc accagtttct cagacaggct aatctttttg tcatctcttt ctccctaaac
    85081 agactctctt atcatgatat tatgctatta tgagcgattt gtcaatccat agcaaccgtt
    85141 ttttagccag ataagcaagc ttttgaccta gaggcagaca agagtggcag tacctcccgt
    85201 tcactgtggt ggctaataag gactaacaca aaatatcaaa cgctttcaaa aacagctcct
    85261 aagcttaaaa aagctgatga acagatttgt tgaacttaag ggagattgcc attattttct
    85321 aatcatttga tgtttaaaat gataaaaaca tgaacttgaa atgaaagaat gagaggagta
    85381 aactagaacc atatcaaaat gatgaaatgg agtgatttta tgaaaacaaa atcaaaacgc
    85441 tttttaaacc tagcaaccct ttgcttggcc ctactaggaa cgactttgct aatgggacgt
    85501 cccgtaaagg cggaggtagt aagtagagac aatagtactg agcagacaga tataatgaaa
    85561 agacgttata tggatagtac aggcataagc gagaaagaat tagaacaaaa atatggggaa
    85621 gatagatttc aaggatattt agacggatat aaagaaggct tggaaaaatc tgatataccc
    85681 aaatggagtg atattaaggt tcctgatggg cgtgacgatg actatagaga tggttatgag
    85741 caaggatttt tagagggaag gcgtgaggct agaccaatag cgtcattctt cgaagctgta
    85801 tggcaagtct taacagatat ctttggtggc tggtttagca gcaacgatag ccctcagtaa
    85861 atgacacatt tgttgtctta atgtagttat tatgacttat tgaaaagctt gaggatactt
    85921 tccttagttc aagcaattct cacactaatc tgctataatt gggatagtcc ctttagtagt
    85981 caggccacct ctgatagggg tggctttttt gggttttagt gacccgtgtg ttgagaaagg
    86041 agtatgtatg ccagaaaaga aagtgttgcc cgtcctaagc atggtggtga gttttgtctg
    86101 cctgcttgat catatcttct tttttgctac ttatagttat ctctacttgc cgcttgtagc
    86161 aagtagtcta gctcttatcg gcctagtgca aaacaaaggc aggcaaaagg tttggtcgct
    86221 agctgggctc atcttagctg ctctagctgt ggcagtagtg gcctatgcct actatgaccc
    86281 aaccgtcatc ccctattaac cttaccccct ctttgcacgc agtcaacatc acaaaaagca
    86341 cccctgacag gtgctttttg tactttagtc aacctcatag cctcgtaaac cctcactgaa
    86401 acagtccctt aaagttccac cactgatctt ggatgctctc acttaaccgc tgatgccaag
    86461 atttatggtc ttcttctctt atctgcttta gcatgctttc ttctagttgt ttttgttcaa
    86521 cgtgctttct ctcttcctca atttgttttt cttctgctag ctgtctttct ttctccttct
    86581 tttctttttc tagtgtcttc gaatccttta attttgtaaa tccgccaaaa aaaccatcat
    86641 cggcacgata aagcagtgtt aattcgtctc cttcatttgg cttatcgaca gttacagtga
    86701 ttggtaaacc accgtctcca tgattgtcat tatatataaa agacagctgt aaattggtat
    86761 tactatgatt agaactttcg ttccccttag ttgatggttt agttattact ttaggacttg
    86821 tatttttttt tccatatgtt tcattattat tttctcgttt ggcatattca tcaagagatt
    86881 cactgtttat ctttaatgga ctatatggtt cactgttatg gttcttcttt tttaaaaaag
    86941 ataccgacta gcctctaggt agtgtaaact gtagcttatt agtaccattt tcagggctaa
    87001 cagtaacgcg aatagctggc gacgtatctg gatctagttc ccacttgatt gcatcctctg
    87061 ctctgacgct actagttacc ccgatggcaa agagtgccag tagcaaggtt aatgtctttt
    87121 tcattttttt ctctcctttt gctcattttt taagacaagg cttattatac caattcttgc
    87181 gctaaaaaga taggaagttc atgtcttgtg ggtgggaaat ggcgcgacta ttcttggtag
    87241 gggcagacag gttttttcct agccagttgc tagccgttgc cattttacct ttgcaatccg
    87301 tttgggcatc aggtcgtgtt ttgaggttgc caatactttt agttgctttt tgacaaaaat
    87361 gcgttatgat agactaaata aaagaagata gcattttcgg tgaatgatgc gtgagtccac
    87421 aaatttattt ttaggagttt atagactgcc taaagtgtct atttcgtcaa taaaggagaa
    87481 caatatgaca tttgaagaaa ttctaccagg tttaaaagcc aagaaaaaat atgtacgtac
    87541 aggttggggt ggtgctgaaa attatgtgca gttgtttgat acccttgaag tggatggaaa
    87601 agtactacaa gcgacacctt attttctgat tcatgttact ggtgcaggtg aaggtttttc
    87661 catgtgggca ccgacaccat gtgatgtgtt agcagaggat tggatcgagg tcaatgacta
    87721 aagttgtttt agtgacgggc tgtgctagtg ggattggtta tgcacaggcc cgctattttt
    87781 tgagacaagg gtatcacgta tatggtgtgg ataaatcgga taaaccggac ttaaacggta
    87841 attttcactt tatcaaattg gatttatcct ctgagttatc cccactattt aaagtggtcc
    87901 ccagtgttga tattttgtgt aatactgcag ggattttaga tgcctacaag ccacttttag
    87961 acgtcagtga tgaagaagtg gaacacctat ttgatattaa tttttttgcg acggtgaagt
    88021 taacgcgtca ttatcttaga cgtatggtgg aaaagcagtc aggtgttatc atcaatatgt
    88081 gctcaatagc aagttttata gcaggtggcg gtggtgttgc ctatacgagt tctaagcatg
    88141 cccttgcggg cttcacgcgt cagctggctt tggattacgc caaagatcag attcacatct
    88201 ttggtatagc gccaggtgct gtcaaaaccg ctatgacggc tagtgatttt gaacctggtg
    88261 gcttagcaga ctgggtagct cgtgagacgc caattggtcg ttggactgaa ccagatgaag
    88321 ttgctgaatt aacgggattt cttgcttcag gaaaagcgag atcaatgcaa ggcgagattg
    88381 tcaaaattga cggtggctgg actttgaaat gatcacatgc cttagcttga gctggcgcag
    88441 taagccctag agatgtgacg agtcaaacag tcaaaggaga tgaacaaatg aaattagcgg
    88501 ttttggggac aggtatgatt gttaaggaag ttttgcctgt cttgcagaaa attgatggta
    88561 ttgatttagt tgctatctta tcaacagtta gaagtttaac gacagctaaa gacctcgcta
    88621 aggcatatca catgcctcta gctacgagta aatatgaggc tgtcttaggc aatgaggaga
    88681 ttgacacggt ctatattgga ctgccaaatc acctgcattt tgcctatgct aagaaggccc
    88741 ttctagcagg taaacatgtc atttgtgaaa agccctttac catgacagca ggagaattag
    88801 atgaactggt gataatcgct aaaaaacgaa aactcatttt gttagaagcg attacgaatc
    88861 agtacctgag taacatgacc tttatcaaag agcatcttga ccaacttggc gatatcaaaa
    88921 ttgtagaatg caattattca caatattctt cacgctacga tgccttcaaa cgaggtgata
    88981 tcgcgccagc ttttaatcct aaaatgggtg gtggagcttt acgtgattta aacatttaca
    89041 acattcattt tgtggtagga ttatttggtc gccctaaaac ggttcaatat ttagccaata
    89101 tggacaaggg cattgacacc tcaggcatgc ttgtcatgga ctatgagcag tttaaagtgg
    89161 tgtgtatcgg ggccaaagac tgcactgcag aaatcaaatc aactatccaa ggtaataaag
    89221 ggtcactggc agtgcttgga gcaacaaata ccctccctca ggttcagtta agtttacacg
    89281 gtcacgaacc acaagtgatt aaccacaaca agcatggcca ccggatgtat gaagagtttg
    89341 tcgcttttag ggacatgatt gaccaaagag actttgagaa agtgaatcag gctttggagc
    89401 atagccgagc tgtcatgtct gtgttggagc gagctgttca ttcgtgatgg taatctggta
    89461 gccattgcct tttgtgcagg tgctatggga atggttgaaa gacgtgtttt cacgagggtt
    89521 aaccccctcg tgcttttttg gcaaaaataa cttgttcagg atttgggcct tctttgtgag
    89581 atgagagatg cctgacgaat tgttttgatt aaaataatga taaagccaaa cgatttaaga
    89641 aatgtccgtt cggaaattct gccccaaaag gtctctaaaa gcagtgaaat cgattttgta
    89701 agcgttgaca cttctgcata actctgttac actaaaagaa tgtcatgaca aaaattacag
    89761 tgtaggagtt taattgttta tggaagagga ttataacaaa agagaacctg agaagtttac
    89821 gcaatttctg cgccgtcaaa aggtcgtctt ttttgtcgca ttttttggtt atgtgtgtgc
    89881 ctacttggta cgcaacaatt tcaaactaat gtcaaacact attatggtgc aaaatggttg
    89941 ggacaaggct caaattgcga ccttgctatc gtgtttgacc gtttcttatg gcttagcaaa
    90001 attctatatg ggggccttag gggatcgtgt tagcttgaga aagctctttt cgatcagctt
    90061 gggtgccagc gctttgattt gtattttaat tggttttttc aatagttcaa tggtggtatt
    90121 agggatactg ctagtcttgt gtggtgtcgt acaaggtgcc ttggcacctg cctcacaagc
    90181 catgattgcc aattattttc caaataaaac acgcggcgga gccatcgctg gatggaacat
    90241 ttctcaaaac atgggatcag ccctcttgcc attaaccatc gccttgctca ccagtatggg
    90301 cttggtggta ccagctaatg gcaatatttt acttgccttt ttaatccctg gcgttttagt
    90361 gttcttgttt gctttgtgtt gctggaagct tggcggtgat aaccctgagt ctgagggact
    90421 tgactctctt cgaacgatgt atggtgatgc gggcgagtca gctgttgcca gtgaagaaga
    90481 aaagtataac ctgtcttatt ggcaactcat ctggaaatac gttttttgta acccgtcgct
    90541 cttacttgtt gctgctgtca atgtggccct ttattttgtt cgttttggga ttgaagactg
    90601 gatgccgatc tacttgtcac aagtagccaa tatgtcagag gctcatatcc attttgcgat
    90661 ttcaatatta gagtgggtag ctattccagg ctcgctggta tttgcgtggt tagcggttcg
    90721 ttatcctaat aaaatggcca agattggggc tattggactt tttgtgttag cggctattgt
    90781 ctttgtctat gaacgcttga ctgccacagg tgctccaaac tatttcttgt tgcttgttat
    90841 tgcaggtatt ttagggtcat tgatttatgg cccacagttg atcgtgaata ttttaacaat
    90901 caactttgtt cctttaaatg ttgcaggaac agcgattggt tttgtaggag taacagctta
    90961 tctcatcggc aatatgggag caaactggct gatgccgatt ttggcagatg gttttggctg
    91021 gttttggtca tatattgtcg ttgcagcttt atctgctttt tcagcggttg gttatttgat
    91081 tttagccaaa cgtgaggaag aaatcatcaa agattagcta ggcaaatgcc taagaaagac
    91141 agacttattg ctgaagtcct gtctttttta ggcatcacaa gccgcaagtg acactataaa
    91201 agacaagaaa atgctatgat gtttcaggaa aaaaagagaa aatatgctat aatgagaagg
    91261 tatttaaatt attatagtaa ggaaaaacaa atgacaaatt atgccattat tttagcagcg
    91321 ggcaaaggga ctcgcatgac ttctgatctc ccaaaagttc ttcataaagt atctggacta
    91381 accatgcttg agcatgtttt tcgtagtgta aaagcgatta gtcctgaaaa agccgtgacg
    91441 gttattggtc acaaatcaga aatggtacgt gctgtcttag cagatcaatc agcctttgtc
    91501 catcaaacag agcagttagg aactggccat gccgtgatga tggcagaaac acaactagaa
    91561 ggactagaag ggcatacctt ggtgattgca ggagatactc ccttgatcac tggagaaagc
    91621 ctgaagagcc tgattgattt tcatgtgaat cataaaaatg tcgccactat tttaacagct
    91681 acggctcaag atccatttgg ttatggtcgt attgttcgca acaaagatgg cgaagtgatc
    91741 aagattgttg agcaaaaaga cgccaatgag tatgagcaac aattaaaaga aatcaataca
    91801 ggaacctatg tgtttgataa caagcgtctc tttgaagcac tcaaatgcat cactaccaac
    91861 aatgctcaag gagagtatta cctgactgat gttgtggcta tttttagagc aaacaaagaa
    91921 aaggtaggag cctatatcct gagagacttc aatgaaagtc ttggtgttaa tgatcgtgtg
    91981 gccttagcaa cagctgaaac agtgatgcgc caacgcatca cccaaaagca tatggtcaat
    92041 ggggtgactt tccaaaatcc tgaaactgtt tatattgaaa gcgatgtaac gattgctcca
    92101 gacgtcctta tcgaaggaaa tgtgacctta aaagggcgta cacatatcgg ctcaggaact
    92161 gtcttgacga atggtactta tattgtggat tctgaaattg gtgataactg tgttgttact
    92221 aattcaatga tcgaatcatc tgttttagct gcaggagtta cggttggccc ttacgcccac
    92281 cttcgtccag gaacgacctt agatagggaa gtccatatcg gtaactttgt cgaggtcaag
    92341 ggttctcaca ttggtgaaaa aacaaaggct gggcatctga cttatattgg aaatgctcag
    92401 gttgggtctt cggtcaatgt tggggctgga accatcactg tcaactacga cggccaaaac
    92461 aaatatgaaa cagtcattgg agatcacgct tttattggga gcaactcgac tctcattgca
    92521 ccactagaaa tcggggatca cgctttaaca gcagcaggtt caacgatttc aaaaacggtt
    92581 cctatcgata gcattgctat tggtcgtagc cgccaagtca caaaagaagg ttatgccaag
    92641 cgcctagcgc atcacccaag tcgaagcaaa taattcaaga tctatttagt aaggaggcca
    92701 ggcatgaaat ttgaagaaaa aacgcttaag agacaaacag tttttgatgg tcatattttt
    92761 aaagttgttg tggatgatgt tgaacttccc aacaatctgg ggcaatccaa gcgagaatta
    92821 atttttcatc gtggtgccgt tgctgttttg gctattactc ctgaacgtaa gattctcctt
    92881 gtcaaacaat accgtaaggc tattgaacgt gtctcatacg agatcccagc gggtaagcta
    92941 gagattggtg aggaaggctc aaagctaaaa gctgctgcac gtgagctgga agaagaaaca
    93001 gcctatacgg ggacattgac gtttttgtat gaattttata cagcgattgg tttttgcaac
    93061 gaaaaaatca cacttttctt agcgacagac ctaacacaag ttgccaatcc caaacctcaa
    93121 gacgacgatg aagttatcga ggtcttagag ttgacatatc aagagtgcat ggacttagtc
    93181 gctcaaggta aacttgctga cgctaaaacg ttgattgctt tgcaatacta tgccttacat
    93241 tttggaggtg agcagtgatg ggaaggccat tgttgaccga tgatatcatc gaaaaagcga
    93301 gacgaatgga aacatttgag ccagatgatg ctgtagactt tgacacaaaa gtaatgacgc
    93361 taccagaaaa agatgaaaaa gcacgcattt ataaaagccg tcggattgaa aatgccaaac
    93421 gaagccaatt gcaatctaaa ttaaatgtga ttttgatagc tgttatgctg ttaattgcca
    93481 tcttggtata tgctatcttt tatctttaaa aaaacgtaag gaaatgatat gaaaatagga
    93541 attattgctg ctatggagga ggagttgtcc ctgctcttag caaatctttt ggatgctcaa
    93601 gaacatcagg tgctttcaaa aacttactat acgggtcgtt ttggcaagca tgagctcatt
    93661 ttggtacagt cgggtgttgg aaaagtgatg tctgctatga cagttgcgat cttggttgag
    93721 catttcaaag cccaagctat tatcaataca ggatcagcag gggcagtcgc ttcacattta
    93781 gcgatcggag atgtggtggt tgcagatcgg ttagtgtatc atgatgtgga tgctactgca
    93841 tttggttatg cttatggtca aatggctggt caaccattat actatgattg tgatccacag
    93901 tttgtggcta tcttcaaaca agtcctaaaa cacgaaaaga caaatggcca agttggtttg
    93961 attgcaacag gagacagttt tgttgctggt caggacaaga ttgacccgat caaaacagct
    94021 tttagcgacg tgttagcagt agaaatggaa ggcgcagcta ttgctcaagc agcacatact
    94081 gcagggaaac ccttcatcgt tgttcgtgcg atgagtgata ccgcagcgca tgatgccaat
    94141 attacttttg atcaatttat tatagaagct ggcaagcgtt cggcccagac attaatgaca
    94201 tttttagaaa acttacctgt ttaactcact ttatcgtgag acaattagct ggataatctc
    94261 tattttagga gtctggtcac ctcttgtttt gaaacctaaa aataagaatt gcagtcactt
    94321 gaccaaacgc tataatgggt taagtaacga tagattacta aaaggagtct aaaaatgaca
    94381 ctaaaaaaac actattatct tctcagtctg ctagctcttg taacttttgg tgctgccttt
    94441 aacacaagcc agagtgtcag tgcacaagtt tatagcaatg gaggatatcg tcaaggtttg
    94501 actgatgaaa aatcacacct gcaatatagt aaagacaacg cacaacttca attgagaaat
    94561 atccttaacg gctaccaaga tgacctaggg aaacactact ctagctatta ttactacaac
    94621 ctaagaaccg ttatgggact atcaagtaag caaaagattg aagaacacta tgaaaagctt
    94681 aagaacaagc tacatgatat gtacaatcat tattaagtca aaggcttaaa aatggcgact
    94741 agcccctcaa aaaaagaggc cacactcatt taaatttaaa tgagtgtggc ctctttttga
    94801 ggagacgcaa ggggttaaag ggctgtgaca tagagttgct tagcaatatt ttcagggatg
    94861 acaagttcct tgtcgccata acaaatcgta taggtttttg caaaggtatc aatttgagtt
    94921 aaggttagct cggtattgat attgaggtga tgtgtttcta gatattggat taaatcaaag
    94981 tggtcgtgga ttctgcttag gcgaaaccgt cccaactccg tgatggtgtt gagagttgta
    95041 gtgttcattt cgacaagagg ctgaccatag cgaggaatag tccctccgtg tgggcagaaa
    95101 tctggaaaat caaggatctt gtctaaacga tcgataaagg tgtctgagac agtgtgctct
    95161 aagacttcag cttcttggtg cacttcttgg gtattatagc ccagctggtg aatcaaaaat
    95221 acctcaatca agcggtgttt gcggtagagg ttagcaacaa gagcatagcc tttgtctttt
    95281 agcaaatagc cttttgcttt atctttgaca atccagcctt gtgaaatcat ttttttaatc
    95341 atctctgaaa cggcaggtgc cgaaacgtgc atcttttctg caaccatttt atttgtaatc
    95401 ttggtttctt gttctccaat ttcatagata catttcaagt aatcttcttt attaggcgtc
    95461 atatcgtttg gcctttctct tatttataat gattattata tcagaatttt taggaaaaag
    95521 cttgacaaaa agcctaaaag aggatatcct tatagcataa ttaactaaac ttaattaaat
    95581 aaataatata tcctaaggag agaaatgatg ggaaagaaaa tgagcctcat tttgggtgct
    95641 tttttatctg tttttctttt agtagcttgt tcgtcaactg gtactaaaac tgctaagagt
    95701 gataaattaa aagtcgtggc aaccaattca attattgccg acatgacaaa agctattgct
    95761 ggtgataaaa tcgatctgca cagcattgtg ccaatcggtc aagaccctca tgagtacgaa
    95821 ccattaccag aagatgttga aaaaacaagt aatgctgatg tgattttcta taatggtatc
    95881 aatctagaag atggtgggca agcttggttc accaaactag tgaaaaatgc tcaaaaaacg
    95941 aaaaacaaag attactttgc cgtgtctgat ggcattgatg tgatttactt ggaaggtgca
    96001 agcgaaaaag gaaaagaaga tccacatgct tggttaaatc tcgaaaacgg aatcatttat
    96061 tcaaaaaaca ttgccaaaca attgattgca aaggatccta aaaacaaaga aacttatgaa
    96121 aagaatctaa aagcttatgt ggctaaattg gaaaaactag acaaagaagc caaatcaaaa
    96181 tttgatgcta ttgcagaaaa taaaaaattg attgtgacta gtgaaggctg cttcaagtac
    96241 ttttcaaaag cttacggtgt cccatctgct tatatctggg aaattaacac cgaagaagaa
    96301 ggaacaccag atcaaatttc atcattgatt gaaaaactaa aagtcatcaa gccatctgcg
    96361 ctttttgtag agtcaagtgt cgatagacgc cctatggaaa ctgtttctaa agatagtggt
    96421 attcctattt attctgagat ctttacagat tcaattgcta aaaaaggtaa acctggcgat
    96481 agttattatg ctatgatgaa atggaacctt gacaaaattt ctgaaggtct agcaaaataa
    96541 gataacaata aagcacagcg gttttagtgt tgtgctttgt tttatttatg taaaggagac
    96601 aaaatgatta caactaacaa tctttgtgtg acctacgatg gcaacagtaa tgctttagaa
    96661 gcgattaatg tgacaattga tggtccttct atcgttggta ttatcggtcc taatggagct
    96721 gggaaatcaa cctttatgaa agctatctta aatcttattg attatcaagg tcacgtaacg
    96781 gttgatggca aagatggtcg taagcttggg catacagtag cttacgtaga acaacgaagc
    96841 atgattgact ataattttcc tattactgtt aaagaatgtg tggcgctagg gacttatagt
    96901 aaattaggcc tttttcgccg agtaggaaaa aaacaatttg agcaggttga taaggttctc
    96961 aaacaagttg gtttagaaga ctttggccat cgaccgataa aatccttatc tggtggtcag
    97021 tttcagcgga tgttggttgc gcgttgcttg attcaagaat cagactatat tttcttagat
    97081 gaaccgtttg ttggcattga ctcggtcagc gaaaaaatca ttgtagatct tttgaaagag
    97141 ctcaaaatgg ctggcaaaac gattttaatt gtacatcatg atttgagcaa agtagagcat
    97201 tattttgaca aactcatgat tttaaataaa catttggtgg cttatggcaa cgtttgtgag
    97261 gtatttactg ttgatacctt gtcaaaagct tatggcaatc atttgatttt aggaaaggag
    97321 atggtgtaaa tgtctatgaa attttttgag ggcttgatgt cataccactt tttacaaaat
    97381 gcactgataa cggctgtagt cattggtatc gtctcaggtg ctgtagggtg ttttattatc
    97441 cttaggtcaa tgtctcttat gggtgatgcc atctcacacg ctgttttacc aggggttgct
    97501 ttgtcattta ttttaggagt caattttttt attggagcga ttgtttttgg gttattagct
    97561 tctgttatta ttacttatat caaggaaaac tctgtcatta aaggagatac ggctattggt
    97621 atcaccttta gctctttttt ggcactggga gtcatcttga taggggtagc caatagttcg
    97681 acggacttat ttcatatttt gtttgggaat attttagctg tgcaagatag cgataagtgg
    97741 attactattg gtgtttcgat ttttgtttta gtggttatta gtctcttttt caaagaacta
    97801 ttattaacat catttgatcc tatcttagcc aaatcaatgg gtgtgaaggt caatgcgtat
    97861 cattatttgt tgatggtcct attaacttta gtggctgtta cggcgatgca aagcgtgggt
    97921 actatcttga ttgttgcctt actgattacg ccagcagcga cagcttattt atatgctaat
    97981 agcttaaaag taatgttagt gatgtcatct ttactaggcg ctttagcatc ggttttaggg
    98041 ctttatttgg gctatacctt taatgttgcc gcagggtcaa gtatcgtact gacttctgcg
    98101 atgatgtttt tgatcagttt ctttgtttca cccaagcaag gctacctcaa aagatggatg
    98161 caaaaaaaag aaaaaacacc ttaaactttt cgttttaaac accttagtgg tttgcaaata
    98221 gtggcaaatg acatcaaagg gtgtttttat atgtcatcaa aagaccataa aaaaccttat
    98281 caaaccaagg tacttagcct attatctgat aaggtttttt aagcatgatt tagtttttaa
    98341 agcgataatc tttgacaatg tcaattgagg taattgtaat gtcttgtttt ggtttatcat
    98401 tttggttgat agaagtcgcg gcaattttat cgacaacatc cataccatca atgacttgac
    98461 caaatacagt ataaccgcca tctaagcttg gattgccgcc atgctcatag gcagagatga
    98521 taggttttgg gtagttggta cttgataatc ccttgctttg atttttcttg ttttggttga
    98581 tataaaattg gctaccgtta gtattagcac cagcatttgc catggcaaga gcaccgcgaa
    98641 tatgatataa aaatggagag atttcgttga caaagccatt gccagcatct tttttaggat
    98701 ccttgccctt ccaaatcgat tcaccacctg tgccatctcc tttggggtca cctgattgaa
    98761 tcataaagtc gttgatcaca cgatggaagg taaggttatc atagtagcct tttttagcat
    98821 gggtgaggaa gttctcaaca gctaagggag catattttgg gaataactta agggtgatgt
    98881 ccccttgact tgtcctcatt acgaccttag cttcttcttt gccgacttct ttggttagtt
    98941 gtggaaattg gctagcatca gctttgagag ctttttgaat gctttcttca taggctttag
    99001 aagctgcttc gctttcttct ttggcagttt tttcatcaat gtatttatcg ccttttatag
    99061 cgcggtcaac agattcacaa gcactcaaac taagtaaact aatggctact aaactgagag
    99121 ataataattt tttcatgtct actcctaaga atgattttct ttattttatc ataaaatgca
    99181 acagaaaata gtagtaaaga gttaaaaacg cctatttttg tgttttatga tctaaccttg
    99241 gttaaaaggc tgctacgact gttattatag cacaagatgc tatagaaaaa cttaaaacac
    99301 cttggttttt tagagctatt tcctaatagt taaaaaatgg tataatagtg ttatggttaa
    99361 aagaaatcaa agaaaaaaaa gtgcgcctaa gaagcgttta acaaaagcag aagtggaaaa
    99421 gcaacgtgcc attaagagga tgattttatc tgttttaatg gctttgttgc ttatttttgc
    99481 gatgcttcgc ttgggcgtct ttggcgtgac aacttataat atgattcgtt ttttggtggg
    99541 tagtttagcc tatccgttta tgtttgcctg gttaatttac ttattttgtt ttaaatggtt
    99601 acggcaaaaa gatggaatga ttgcgggagt tgttattgcc tttttgggat tgctagttga
    99661 gtggcacgcc ttcttatttg cgatgcctag gatgcttgat caagatattt ttctaggcac
    99721 tgcgcggcta attacaagag atttactagc cctgcgcgtg actgaatttg ttggtggagg
    99781 aatgcttggt gcattacttt ataaacccat agccttttta ttttcgaata tcggctctta
    99841 ctttattggt tttttgttta tcttattagg attatttcta atgacgcctt gggatatcta
    99901 tgatgtgagt cactttgtga aagaggctgt tgataaacta gcagtggctt atcaggaaaa
    99961 taaagaaaag cggttcatca aacgagaaga gcaccgctta caagctgaaa aagaggcttt
   100021 agagaaacaa gcacaagagg aagaaaaacg tctagcagaa ttgacggttg atcctgagac
   100081 gggagagatt gttgaggata gtcagtctca agtcagctat gatttggctg aggatatgac
   100141 aaaagaacca gagattcttg cttatgatag tcacctcaaa gacgatgagg caagcttatt
   100201 tgaccaagaa gacttggctt atgctcatga ggaaattggg gcttatgact ctttatctgc
   100261 tttagcatct tctgaagatg agatggatat ggatgaacct gttgaagttg atttcacgcc
   100321 aaaaacccat cttctttata aacttccaac gatagattta tttgcaccag ataagcccaa
   100381 aaaccagtcc aaagagaaaa acttagtccg caaaaatatc aaggtgcttg aagatacctt
   100441 ccaaagtttt gggattgatg tcaaggtaga acgagctgaa attggaccat cagttactaa
   100501 atatgaaatt aaaccagctg tcggggtccg agttaatcgt atttcaaatc ttgctgatga
   100561 tttggcactt gctctggctg ctaaagatgt tcgtattgaa gcaccaattc ctggaaaatc
   100621 attaataggt attgaagttc ctaactcaga aattgcaacg gtttctttcc gcgaactttg
   100681 ggaacaatct gatgccaatc ctgaaaatct tttagaagta ccactaggta aagctgttaa
   100741 tggcaacgct cgcagtttta acttagctag aatgccgcat cttttggtag ctgggtcaac
   100801 tggttcaggt aaatctgtgg cagttaatgg cattatttca agtattttga tgaaggcacg
   100861 tccagatcaa gttaagttta tgatgattga ccccaaaatg gttgaattat ctgtttataa
   100921 tgatattcca catttattaa tccctgttgt aaccaatccg cgtaaagcca gtaaggcact
   100981 ccaaaaagtg gttgatgaga tggaaaaccg ctacgagtta tttagtaaaa ttggtgtgcg
   101041 taatatagca ggttataata caaaggttga agagtttaat gcttcttctg agcaaaaaca
   101101 aataccgttg actttaatcg ttgtcattgt agatgaattg gctgacttga tgatggttgc
   101161 tagtaaagaa gttgaagatg ctattattcg tttggggcaa aaagcgcgtg ctgcaggtat
   101221 ccatatgatt cttgcaactc aacgtccctc tgtagatgtt atttctggtt tgattaaagc
   101281 aaatgttccg tcgcgtatgg catttgctgt ttcaagtggt actgatagcc gtacgatcct
   101341 tgatgaaaat ggtgctgaaa agctcttggg acggggtgat atgctcttta agccgattga
   101401 tgaaaatcac cctgttcgct tgcaagggtc tttcatctca gatgatgatg tggagcgtat
   101461 tgtcaacttt atcaaagacc aagctgaagc ggattatgat gacgcctttg atcctggtga
   101521 agttagcgac aatgatcctg gtttttctgg aaatggcgga gctgctgaag gtgatcctct
   101581 ttttgaagaa gcaaaagcct tggtcttaga gacacaaaaa gctagtgcct caatgattca
   101641 aaggcgtttg tcggttggat ttaatcgtgc cacgcgcttg atggatgaat tggaagaagc
   101701 aggtgttatc ggtccagcag aaggaaccaa acctcgtaag gtattgcaga caaactaaaa
   101761 gaacctgacg tctcataatg agatgtcagg ttcttttttt gtgatgtcag gccagttgat
   101821 gagatgccta tgctaatgta aaaataaaga taactagaat aaggtagaaa ataacggtga
   101881 ctaaaaagcc aactcgccaa aatagcttca taaagcgatg gtaagaaaac gactgagttc
   101941 ggatgactag cagtagtgaa atgacgatgg ctagcagcga catgataata agataataag
   102001 gcagtaaatt atggatgaaa aattttcctg agacaagcac aatttctatc gcaaaaagta
   102061 aaagtgcgac atctggaaat ttaaatccct ttttattaag tttaaataaa gaggttacaa
   102121 tcatggcaaa aagaggcgtt actatcaaga aagctaaggc agttaattta tagatcatca
   102181 taggtctatt ttatactcaa atcccttact tgtaaactga tacttacctg ttgtgataga
   102241 aactgatctt tgagagggaa agagcctgct tcaatttaaa tattgcaaaa ggcatcagct
   102301 attttaacac gccaaacgca tgaagaaact tttgttttca gaaaactaga tttataatga
   102361 caaaatcaat caaagtagta cactatagat gaggtgacta cgatgattga ttttattatt
   102421 tctattgatg attgcgcagt tgaattggat agtcgtcaat cttggaaaat tcgctccccc
   102481 ttatcaacca ttctatttct tgtcttcgtt tgtcagttag ctggcattga aacctggaag
   102541 gagatggaag attttattga aatgaatgaa ccattgtttg cgacctacgt tgatttgagt
   102601 gaaggttgtc cgtcccatga taccttagag cgtgtgatta gtcttgttaa ttcagaccgt
   102661 ttaaaagagc ttaaagttca atttgagcaa tcattgacaa gcttagatgc cgttcatcaa
   102721 ctgatttcag tggacggtaa aacgattcga ggcaatcgag gtaaaaatca gaagcctgtt
   102781 catattgtaa cggcttatga tgggggtcat catcttagtt tgggacaggt agcggttgag
   102841 gagaaaagta atgaaattgt tgccattcct cagttattgc ggacaattga tatccgtaaa
   102901 agcattgtaa cgatagacgc aatgggcacg cagacggcta tcgttgatac gattattaaa
   102961 ggtaaagcag actattgctt agccgtcaaa ggaaatcaag aaacacttta tgatgatatt
   103021 gctctttatt ttagtgatgt caacttattg gaagaactct aagaaaatgc gcagtattat
   103081 cagactgttg aaaaatctag gggacagatt gaagttagag aatactgggt gtcttccgat
   103141 atcaaatggt tgtgtcaaaa ccatcccaaa tggcataagt tacgtggtat tgggatgatt
   103201 cgtaacacga ttgataagga tggtcagctg agtcaagaga atcgttattt tatctttagc
   103261 tttaagaatg tgcttatatt ttctcaaagt gatggtattt cctaaaaaag acctcagtta
   103321 tcgtcgcaaa caacggtata tttctgtcca tttggaagat tatttagtcc aattatttgg
   103381 agaaagaggc taagcagatg attgatttaa aaaggaatct tttcaaaatt gatgtccggg
   103441 cacaaaagga tgaagagaaa gttttcatgc gtacggcgtg ctattttaac aaaaagactt
   103501 gatttatttt ggcaataagc tataatggta aggtatgcaa tattgcatat ctgtgggagg
   103561 taaaaatctc aattaccgcc aaaaccacaa caggaggatt tttaaaatgg ctaaaaaagt
   103621 cgaaaaactt gtaaaacttc aaatccctgc tggtaaagct acaccagctc cgccagttgg
   103681 accagctctt ggtcaagcag gtatcaacat catgggcttc actaaagaat ttaacgctcg
   103741 tacagctgat caagctggta tgatcatccc agttgttatc tcagtttatg aagacaaatc
   103801 atttgatttc atcactaaaa caccaccagc tgctgttctt ttgaaaaaag ctgcaggtgt
   103861 tgaaaaagga tcaggtacac ctaacactac taaggttgcg acagttactc gtgcacaagt
   103921 acaagaaatt gctgaaacta agatgccaga tttgaacgct gcaaacattg aagctgcaat
   103981 gcgtatgatc gaaggtactg ctcgttctat gggattcact gttactgact agtcagtcaa
   104041 gaacccctat tacccgcacg acttcatcat aagagatgag tgacgtggga gattttaaat
   104101 caaatcgata tgaccacatt acaaggagaa ttttaaaatg gctaaaaaaa gcaaacaaat
   104161 gcgtgctgca cttgaaaaag tagatagcac aaaagcgtac agtgtagaag aagctgtagc
   104221 attagtaaaa gaaacgaact tcgcaaaatt tgatgcgtct gttgaagttg cttacaactt
   104281 gaacattgac gttcgtaaag cagaccaaca aatccgtggc gcaatggtat tgccaaacgg
   104341 aactggtaaa acacaacgtg ttcttgtttt tgcacgtggt gcaaaagctg aagaagcaaa
   104401 agcagctggt gcagacttcg taggtgaaga cgaccttgtt gcaaaaatca atggtggatg
   104461 gcttgacttt gacgttgtta tcgcaacgcc agacatgatg gctatcgtag gtcgtcttgg
   104521 acgtgtcctt ggacctcgta acttgatgcc aaaccctaaa actggtacag taacgatgga
   104581 tgttgccaaa gccgttgaag agtctaaagg tggtaaaatc acttaccgtg ctgacaaagc
   104641 aggtaatgtt caagctctta ttggtaaagt ttcatttgat gctgacaaat tggttgaaaa
   104701 cttcaaagcc ttccacgatg taatggctaa agctaaacct gcaacagcta aaggaactta
   104761 catggcaaac gtctcaatca catcaacaca aggtgttggt atcaaggttg atcctaactc
   104821 actttaagaa aaaattaggg caacgcctaa tcatagcaaa aagacaaatt tctgaagata
   104881 aatcttcact agaggtttgt cttttttatg gtttaaaatg gaatgcaaac aaaaaagtgt
   104941 aggcgataat accatgaaag gagttgattc tcttaataag atgtggagtt aacacatcat
   105001 gagctcacaa aaaatgataa aggaagtatc ggtggtgtga aaaaagggat ttt
//
LOCUS       DAXMQE010000002        96351 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.002, whole genome shotgun sequence.
ACCESSION   DAXMQE010000002 DAXMQE010000000
VERSION     DAXMQE010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 96351)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 96351)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..96351
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.002"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            complement(<1..487)
                     /locus_tag="ACF4ZO_000107"
     CDS             complement(<1..487)
                     /locus_tag="ACF4ZO_000107"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014712716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HFD5485694.1"
                     /translation="MSKNLLIELGLEELPAYVVTPSEKQLGERLATFLTENRLSFEDI
                     QTFSTPRRLAVRVSGLAAQQTDLTEDFKGPAKKIALDADGNFSKAAQGFVRGKGLTTD
                     AIEFREVKGEEYVYVTKHEAGKPAKEVLLGVTEVLSAMTFPVSMHWANNSFEYIRPVH
                     TL"
     gene            complement(865..1782)
                     /gene="glyQ"
                     /locus_tag="ACF4ZO_000108"
     CDS             complement(865..1782)
                     /gene="glyQ"
                     /locus_tag="ACF4ZO_000108"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HFD5485695.1"
                     /translation="MSKKLTFQEIILTLQQYWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLASLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATSPVTAE
                     VTYGLERLASYIQEVDSVYDIEWAPGVKYGEIFLQPEYEHSKYSFEMSDQDMLLENFE
                     KFEKEASRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKKLGFPLLDEATRAILLAEDDE"
     gene            complement(2154..2687)
                     /locus_tag="ACF4ZO_000109"
     CDS             complement(2154..2687)
                     /locus_tag="ACF4ZO_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HFD5485696.1"
                     /translation="MTIFLVMLAMFTIRLVFLKKSITNEKAILAQGGQEFGAQNTKFL
                     TLLHIMIYVFAVIEALLKQIKFDGISFLGLLLMLLSVAVLYEVTRILGDIWTVKLMLA
                     KDHKYVDHWLFKTIKHPNYFLNIAPELVGIALLCHAKITAMLLFPCYIVVIYLRIREE
                     NKLLAEVIIPNGTRTKP"
     gene            complement(2822..3661)
                     /locus_tag="ACF4ZO_000110"
     CDS             complement(2822..3661)
                     /locus_tag="ACF4ZO_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HFD5485697.1"
                     /translation="MVTTVKMTSGYEIPVLGFGTYQAADGEEAYQSTLAAIKADYRHI
                     DTAAIYKNEESVGRAIKDSGVLREDLFITTKLWNDAHSYEGAKDALAASLDRLGLDYV
                     DLYLIHWPNPKALRNTWKEANAQAWQYMEEAVEAGLIKSIGVSNFMVHHLEALQETAK
                     ITPAINQIRLAPGCYQKEVVDYCKANEILLEAWSPLGQGEIFDNETMQQLANKYDKTV
                     AQVALAWSLAEGFIPLPKSVHDERIKENMAIFDVSLTPEDKKTIRYLSGMSAIPNPDT
                     TSF"
     gene            complement(3783..4931)
                     /gene="nagA"
                     /locus_tag="ACF4ZO_000111"
     CDS             complement(3783..4931)
                     /gene="nagA"
                     /locus_tag="ACF4ZO_000111"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008448 - N-acetylglucosamine-6-phosphate
                     deacetylase activity [Evidence IEA];
                     GO_process: GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HFD5485698.1"
                     /translation="MTCYLKADCFYYPTEVKPAGYLSLHDGVFGEWTEIVPADAQIID
                     YTGYQIAPGLVDTHIHGYAGADVMDNSAQGIHQMSEGLLATGVTSFLPTTLTSTFEQL
                     EKVSGTIASVADQVKGAKIQGIYFEGPYFTEEYKGAQNPSYMKNPRLEEFDAWQKAAK
                     GLIKKIALAPERDGVKEFVSAVTKQGVTVALGHSNGTYQEAKEAVQAGASVWVHAYNG
                     MRGLTHREPGMVGAVYNLPNTYAELICDGHHVSPIACDILMKQKGHDHVAMITDCMRA
                     GGSPDGDYLLGEFSVVVANGTARLKESGNLAGSILKLKDGLRNVVAWGIATPAEAIHM
                     ATYVPAVSVGIDDVCGQIKAGHAADFIVLDKDLTLVATYLNGQKAFDA"
     gene            complement(5049..6680)
                     /locus_tag="ACF4ZO_000112"
     CDS             complement(5049..6680)
                     /locus_tag="ACF4ZO_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0005436 - sodium:phosphate symporter
                     activity [Evidence IEA];
                     GO_process: GO:0044341 - sodium-dependent phosphate
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HFD5485699.1"
                     /translation="MSVNWQDIAFHFFGGLGLFLFSIKYMGDGLQQAAGDKLRYYIDK
                     YTSNPFFGILVGIAMSALIQSSSGVTVITVGLVSAGLLNLRQAIGIVMGANIGTTITS
                     FLIGFKLGDYALPMIFIGAACLFFTSNKKLNNFGRIIFGVGGIFFSLNLMGDAMDPLK
                     SVSAFQNYLATLGDKPFQGVFIGTALTMLIQSSAAIIGILQGLFSGGLLTLQGAIPIL
                     LGSNIGTCITAVLAAIGSNIAAKRVAAAHVLFNLIGTIIFMIILVPFTSLMLWLQSKL
                     SLTPEMTIAFSHGSFNITNTILLIPFISLLAMIVTRLIPGEDEVVKYEALYLDRLLIT
                     QAPSIALGNAHKELVHLASYAIQAFEASYSYIMTADDKFGEKVKRYERAVDTIDEELT
                     TYLVDISNEALSPSENEVLAGILDSSRDLERIGDHSESLGILIEGIISKQIGFSISAR
                     QELTEMYQLTHCLTLDAIRAIVDSDTDLAQTIVTRHKEIEEKERRLRKTHIKRLNCGE
                     CTAQAGINFIDIISHYTRITDHALNLAEKVLSHQL"
     gene            6882..7604
                     /locus_tag="ACF4ZO_000113"
     CDS             6882..7604
                     /locus_tag="ACF4ZO_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5485700.1"
                     /translation="MATMKQYHKGDSMTKSQKEALYWMLSVLTITLIGGSCLIFGSHP
                     QTQDKVAKHSKSAASLLKKAVKAVNDADRLATAAAIQEAQKAVDKLAESSKKKTLQEQ
                     LNVAKAKQEQEDAATQAVKAAEETLNQNLKDIAQKAVNDLSNKGKKAALQSRLDAILP
                     AKPIIDEFPRQSGEITDNSYWTPFPGDVSDTYDNSQSPTLDPSSESSASDVTPQPSHP
                     DPIPPQTSSEPSDSGDKQSSKE"
     gene            complement(7733..8575)
                     /locus_tag="ACF4ZO_000114"
     CDS             complement(7733..8575)
                     /locus_tag="ACF4ZO_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HFD5485701.1"
                     /translation="MTWKIVTDSGCDLRSLTRQSKELRFERVPLTLQIGTEIFRDDDG
                     LDIDNMMTTMYQSSKATTSSCPSPEAFLQAYRGADNVIVMTITGTLSGSHNSARLAKN
                     ELLEENPNVNIHLIDSLSAGGEMDLLVLELERLINLGLSFEEVVKQITAYQQKTRLIF
                     VLAKVDNLVKNGRLSKLVGKVIGLLNIRMVGKASNKGTLELLQKARGQKKAVSALIEE
                     IQKEGYVGGKVYIAHAQNPKICEQISEKIKSLYPDAVIQTGRTSGLCSFYAEDGGLLM
                     GYEI"
     gene            8868..9425
                     /locus_tag="ACF4ZO_000115"
     CDS             8868..9425
                     /locus_tag="ACF4ZO_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFD5485702.1"
                     /translation="MTDKALSKRSLQNLTQFNKETRRIARESMEIALLNLLETKPLGD
                     ITISELVTKAGVSRNAFYRNYTSKEAIIEQLLVGVIRRIFRGLKQFDIKTQAYQAWLY
                     LFTEAKKEAQLLKMIFKHHLHHLLTRLVTKRLKAYQKLKDKKQSHYKRLFWSNAIVSV
                     LTNWISDDMIVPAEEMAAMGLPLLT"
     gene            complement(9461..10285)
                     /locus_tag="ACF4ZO_000116"
     CDS             complement(9461..10285)
                     /locus_tag="ACF4ZO_000116"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFD5485703.1"
                     /translation="MIQLIAIDLDGTLLNQDKQIPKENITAIQEAAQSGLKIVLCTGR
                     PQSGTRPYFDQLGLTQEEFLIINNGCSTYSSPDWQLRHSKMLKVSDIELLEELSQSFP
                     DIYLTLTEENDYLVLEEEVPDLVQEDGDLVFTIVKPVSLAELSDTPRLIFQAMYLGEK
                     AALDAFERAVRNQLSQSFHVVRSQDNILEILPQGVSKASALKELVEDLGLTADQVMAI
                     GDAPNDIEMLTYAGLGVAMENASAAIKPLADKVTLTNDMAGVAQAIRQFALAAQKD"
     gene            complement(10287..10904)
                     /locus_tag="ACF4ZO_000117"
     CDS             complement(10287..10904)
                     /locus_tag="ACF4ZO_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trimeric intracellular cation channel family
                     protein"
                     /protein_id="HFD5485704.1"
                     /translation="MTIDMWEILNIIGTIAFALSGAIVAMEEEFDILGIFILGFVTAF
                     GGGAIRNTLIGLPIEALWGQKPEFTCAFFAMVLIMLFPKLIARGWVRAAVLTDAIGLA
                     AFSVQGALHAVRLNQPLSAVIVAAVLTGAGGGVVRDILAGRKPSVLRSEIYAGWSILA
                     AIVLHFKLADSTIECYALVVLLTTLRMIGNRKKWNLPKIKWKEER"
     gene            complement(11101..12078)
                     /gene="lacD"
                     /locus_tag="ACF4ZO_000118"
     CDS             complement(11101..12078)
                     /gene="lacD"
                     /locus_tag="ACF4ZO_000118"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009025 - tagatose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HFD5485705.1"
                     /translation="MTITANKRHYLEKVSHQGIISALAFDQRGALKQMMAAHQEGEAT
                     VTQIETLKVLVSEELTPYASSILLDPEYGLLATKVKANQTGLLLAYEKTGYDATTTSR
                     LPDCLVEWSVKRLKAAGADAIKFLLYYDVDGDEQINLQKQAYIERIGSECTAEDIPFF
                     LELLSYDERISDNNSAAYAKLKPHKVNGAMSVFSDKRFGVDVLKVEVPVNMAYVEGFT
                     EGEVHYSQAEAIKAFQDQEAASHLPYIYLSAGVSAKLFQETLYFAAAAGAQFSGVLCG
                     RATWAGSVPVYITKGEDEARKWLCTEGFQNIDELNRVLEETASPWTEKI"
     gene            complement(12160..12567)
                     /locus_tag="ACF4ZO_000119"
     CDS             complement(12160..12567)
                     /locus_tag="ACF4ZO_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HFD5485706.1"
                     /translation="MSLTVILNPSVAISYPLDCLAMDTVNRVDRTAKTAGDKELNVTK
                     SWSVMATGFSGGKLGDFIIHQLQEQGISNQFFKIKGETRNCIAVLNEGMQTKILEAGP
                     YSDVDEAEVSLSHMSTIAKPFDVLTSQAVCLRD"
     gene            complement(12577..13092)
                     /gene="lacB"
                     /locus_tag="ACF4ZO_000120"
     CDS             complement(12577..13092)
                     /gene="lacB"
                     /locus_tag="ACF4ZO_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HFD5485707.1"
                     /translation="MKIAIGCDHIVTNEKMAVSDFLKSKGYDVIDCGTYDHTRTHYPI
                     FGKKVGEAVVNGQADLGVCICGTGVGINNAVNKVPGIRSALVRDMTTALYAKEELNAN
                     VIGFGGKITGELLMCDIIDAFIKAEYKETEENKKLIAKIAHLESHHANQEDPDFFTEF
                     LEKWDRGEYHD"
     gene            complement(13107..13532)
                     /gene="lacA"
                     /locus_tag="ACF4ZO_000121"
     CDS             complement(13107..13532)
                     /gene="lacA"
                     /locus_tag="ACF4ZO_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HFD5485708.1"
                     /translation="MAIILGADAHGNALKELIKSFLQEEGYDIIDVTDINSDFIDNTL
                     AVAKAINEAEGRLGIMVDAYGAGPFMVATKLKGMVAAEVSDERSAYMTRGHNNARMIT
                     IGAEIVGPELAKNIVKGFVTGPYDGGRHQIRVDMLNKMA"
     gene            complement(13789..15240)
                     /locus_tag="ACF4ZO_000122"
     CDS             complement(13789..15240)
                     /locus_tag="ACF4ZO_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HFD5485709.1"
                     /translation="MMQPFLDIINKILGFPIQLGSGVVMLIVMTGLAMIFGVKFTKAL
                     EGGIKLAIALTGIGAIIGILTGAFSESLQAFVKNTGISLNIIDVGWAPLATITWGSPY
                     TLYFLLVMLVVNIVMIVMKKTDTLDVDIFDIWHLSITGLLIMWYAARNHLPVFVSLLI
                     ATVAVILVGVLKIINSDLMKPTFDDLLGTGSQSPMTSTHMNYMMNPIIMVLDKIFDKV
                     FPGLDKYDFDAAKLNKKIGFWGSKFFIGMALGFVIGIMGDPHFTVESIKNWFGLGFTA
                     GACLELFSLIGSWFIAAVEPLSQGITNFANARMHGRRFNIGLDWPFIAGRAEIWACAN
                     ILAPIMLIEAVLLSKVGNGILPLAGIIAMGMTPALLVVTRGRLIRMIIFGSLLLPLFL
                     LSGTMIAPFATELAKKVGAFPAGTSAGSLITHSTLEGPMEKIFGYVIGQATTGQIASI
                     ITLIIFVAIYLGLFAWYANQMKARNAEYAKTMT"
     gene            complement(15266..15571)
                     /locus_tag="ACF4ZO_000123"
     CDS             complement(15266..15571)
                     /locus_tag="ACF4ZO_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFD5485710.1"
                     /translation="MIKILAACGAGVNSSHQIKDAIETQMSDRGYDVHCDAVMVKDIT
                     EELVSRYDIFTPIAKTDLGFEMPIPTVEAGPILYRIPNMSEPVFAELERVIKENHLQ"
     gene            complement(15564..16037)
                     /locus_tag="ACF4ZO_000124"
     CDS             complement(15564..16037)
                     /locus_tag="ACF4ZO_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009881202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFD5485711.1"
                     /translation="MFPNILFTEARTQPELFDLVASHLEKVGYVTQEYHQALVEREAV
                     FPTGLKVDLKDGSDILYAAIPHTETKYCLVDQVVYVRNSQALTFKHMINPEEDCLVTD
                     FFFIINSQNEGQTTILSNLITFFITKGNLSYLASLKDDKQAISNYLIEKGVFQHD"
     gene            16274..17044
                     /locus_tag="ACF4ZO_000125"
     CDS             16274..17044
                     /locus_tag="ACF4ZO_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFD5485712.1"
                     /translation="MLKRERLLKITEIVNEQGIVTVNDIIQTLNVSDMTVRRDLDELE
                     KAGKLIRIHGGAQSITMPNKKERSNIEKQTVQTKEKWELASYATQLVNDGETIFIGPG
                     TTLECFAEQLKNRQIRIVTNSLPVFNILQDSETIDLILIGGEYRSITGAFVGSLASQN
                     ISSLKFAKAFISCNGIYKNDIATYSETEGEIQKLAFNNSIEKYLLVDNQKFNAYDFFI
                     FYHLNNIDAVVTDSQITEDVIERYSQFTQLLVAHENKE"
     gene            complement(17248..17451)
                     /locus_tag="ACF4ZO_000126"
     CDS             complement(17248..17451)
                     /locus_tag="ACF4ZO_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-associated domain-containing
                     protein"
                     /protein_id="HFD5485713.1"
                     /translation="MEKHYQVTGMTCDGCARTVTKKLSAVPGVQSVQVNLEKGEAKVT
                     GRPLTFLLKRALKATKFELHKWS"
     gene            complement(17465..19696)
                     /locus_tag="ACF4ZO_000127"
     CDS             complement(17465..19696)
                     /locus_tag="ACF4ZO_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042625 - ATPase-coupled ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFD5485714.1"
                     /translation="MAKEIFLVEGMSCASCALTIEKTVNQLPEVEQAVVNLATEKLTV
                     TYQDDDLETAKVIQAVKAAGYGAQVFDEHAKHMQTGRRDEDLKVIWSQVLWSALFTIP
                     ILYLAMGHMVGLWLPPFLQPDRYPFVYSFSQLLLTIPVLVLNRHYYHNGFKALFKGHP
                     NMDSLVALATSFAFAYSLYGVVEISLGQAHFVHSLYFESVVVILTLIGLGKYFESRSK
                     GRTSQAIQKLLSLKATDVRVWRNSQWQLLPLEEVSYDDLVLVQPGEKVSIDGIIVEGH
                     SSLDESFLTGESLPVEKGEKDNVFAGSLNGPGALTIKPDKLGNDTLLAQIIQLVENAQ
                     ENKAPIAAIADRVSGVFVPVVLVLALLTGVFWLVFMQESFRFSLTTAIAVLVIACPCA
                     LGLATPTAIMVGTGRAAENGILFKGGDILEQAHQVDTVVFDKTGTVTEGKPSLQKLLI
                     FSGDDHLILQEAASLEAYSQHPLGEAIVRAAQEAGYDSLPVEEFESLTGLGVTGQLEG
                     RRLAIGNAALMGILGIDLSCVQSVCAKASGKGQTLVYYAKEGQLRALFSIADAVKEDS
                     QATVEALHQLGIHTIMLTGDHDATAKAIASQVGITDVISQVLPDQKAGVIADLRSQGR
                     KVAMVGDGINDAPALAVADIGIAMGSGTDIAIESADVILMKPDMLDLVKAMSLSRATM
                     RIVKENLFWAFIYNVLMIPVAMGLLHLFGGPLLNPMLAGFAMSFSSVSVVLNALRLKG
                     KTI"
     gene            complement(19696..20130)
                     /locus_tag="ACF4ZO_000128"
     CDS             complement(19696..20130)
                     /locus_tag="ACF4ZO_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006825 - copper ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HFD5485715.1"
                     /translation="MQQISAAEWEVMRVVWASGDIKSSDIITILRKKYQWSDSTIKTL
                     IGRLVEKKALETYREGRAYIYQALLDETLLQKEALATVLDGICQRQHARLLLERLYDL
                     PMTLEEIEAFQELLELKKENAVLEVPCNCLPGQCHCQKKETY"
     gene            20314..21291
                     /locus_tag="ACF4ZO_000129"
     CDS             20314..21291
                     /locus_tag="ACF4ZO_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFD5485716.1"
                     /translation="MRKTLVTLGLLLTLCLPTPVAASSRSWKSWFIEQYFWLKRDKSY
                     YSKQDDPSFQRYLDACREQSDKPYQLDTNLVNGPLVQENLYGMQVYSWNDNGKPDQKT
                     IIYLAGGSYLNNPTTYHINMLKTLSTSLDAKIVLPIYPKAPRYTYNYTMPKLVNLYQH
                     YYHKNQNIFLMGDSAGGGLALGLAHALHNESVPQPKQLVLLSPWLDVTMSHPEIPKYE
                     DADPILSSWGLKRVGELWAYSADNTNHIYVSPKNGPITYLPPITLFTGTREIFYPDIR
                     DYAAKLKAANHNITFITQEGMNHVYPIYPIEEAKTAQYQIIDAINKTPQ"
     gene            complement(21421..21771)
                     /gene="rbfA"
                     /locus_tag="ACF4ZO_000130"
     CDS             complement(21421..21771)
                     /gene="rbfA"
                     /locus_tag="ACF4ZO_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HFD5485717.1"
                     /translation="MANHRIDRVGMEIKREVNDILQKKVRDPRVQGVTITEVQMQGDL
                     SLAKVYYTIMSDLASDNQKAQTGLEKATGTIKRELGKQLTMYKIPDLVFEKDNSIAYG
                     NKIDQLLRELDNKS"
     gene            complement(21977..24838)
                     /gene="infB"
                     /locus_tag="ACF4ZO_000131"
     CDS             complement(21977..24838)
                     /gene="infB"
                     /locus_tag="ACF4ZO_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HFD5485718.1"
                     /translation="MSKKRLHEIAKEIGKSSKEVVEHAKYLGLDVKSHASSVEEADAK
                     KIISSFSKASKPDVTASQTVKPKEVAQPSVTVVKETGSEHVEKTQVSKPKSRNFKAER
                     EARAKEQAARKQANGSSHRSQERRGGYRQPNNHQTNEQGDKRITHRSQGDTNDKRIER
                     KASNVSPRHDNHQLVGDRNRSFAKENHKNGRFTNQKKQGRQEPQSKSPKIDFKARAAA
                     LKAEQNAEYSRQSETRFRAQQEAKRLAELARQEAKEAALKAQAEEMSHRETALKSIEE
                     AETKLKSSNISAKSTADNRRKKQARPEKNRELTHHSQEGQKKNKKSWNSQNQVRNQKN
                     SNWNKNKKTKKGKNVKNTNTAPKPVTERKFHELPKEFEYTEGMTVAEIAKRIKREPAE
                     IVKKLFMMGVMATQNQSLDGDTIELLMVDYGIEAKAKVEVDDADIERFFEDENYLNPE
                     NIVERAPVVTIMGHVDHGKTTLLDTLRNSRVATGEAGGITQHIGAYQIEEAGKKITFL
                     DTPGHAAFTSMRARGASVTDITILIVAADDGVMPQTIEAINHSKAAGVPIIVAINKID
                     KPGANPERVIAELAEYGIISTAWGGECEFVEISAKFNKNIDELLETVLLVAEVEELKA
                     DPTVRAIGTVIEARLDKGKGAIATLLVQQGTLHVQDPIVVGNTFGRVRAMVNDLGRRV
                     KSAEPSTPVSITGLNETPMAGDHFAVYADEKAARAAGEERSKRALLKQRQNTQRVSLD
                     NLFDTLKAGEIKTVNVIIKADVQGSVEALAASLVKIEVEGVRVNVVHSAVGAINESDV
                     TLAEASNAVIIGFNVRPTPQARQQADTDDVEIRLHSIIYKVIEEVEEAMKGKLDPVYQ
                     EKILGEAIIRETFKVSKVGTIGGFMVINGKVTRDSSVRVIRDSVVIFDGKLASLKHYK
                     DDVKEVGNAQEGGLMIENFNDLKVDDTIEAYIMEEIVRK"
     gene            complement(24858..25160)
                     /locus_tag="ACF4ZO_000132"
     CDS             complement(24858..25160)
                     /locus_tag="ACF4ZO_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HFD5485719.1"
                     /translation="MTNLERLSSLIGLAQRAGKVISGEELVVKAIQHQQVILVFLAND
                     AGPNVTKKVTDKSNYYNVEVSTVLNALELSAALGKPRKVAAIADAGFSKKMRTLME"
     gene            complement(25153..25449)
                     /locus_tag="ACF4ZO_000133"
     CDS             complement(25153..25449)
                     /locus_tag="ACF4ZO_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006531117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HFD5485720.1"
                     /translation="MSKVKKIPLRKSLVSGEIIAKRDLLRIVKTKDGQVFIDPTGKQN
                     GRGAYIKLDNQEALMAKKKQVFNRSFSMDIPESFYDDLIAYVDHKIKRRELGLD"
     gene            complement(25465..26622)
                     /gene="nusA"
                     /locus_tag="ACF4ZO_000134"
     CDS             complement(25465..26622)
                     /gene="nusA"
                     /locus_tag="ACF4ZO_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor NusA"
                     /protein_id="HFD5485721.1"
                     /translation="MSKEMLEAFRILEEEKHIDKADIIDAVTESLKSAYKRRYGQSES
                     CVIEFNEKTADFQVFTVREVVEEVFDSRLEISLKDALAISSAYELGDKIRFEESVNEF
                     GRVAAQSAKQTIMEKMRRQMREVMFNEYKEHEGEIMTGTVERFDQRFIYVNLGSLEAQ
                     LSHQDQIPGETFKSHDRIDVYVYKVENNPKGVNVFVSRSHPEFIKRIMEQEIPEVFDG
                     TVEIMSVSREAGDRTKVAVRSHNPNVDAIGTIVGRGGSNIKKVISKFHPKRVDAKTGL
                     EIPVEENIDVIQWVDDPAEFIYNAIAPAEVDMVLFDDEDLKRATVVVPDSKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEYDRLEAEKEAATVVEEPVVDDVMTAEEV"
     gene            complement(26797..27333)
                     /gene="rimP"
                     /locus_tag="ACF4ZO_000135"
     CDS             complement(26797..27333)
                     /gene="rimP"
                     /locus_tag="ACF4ZO_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0042274 - ribosomal small subunit
                     biogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HFD5485722.1"
                     /translation="MDSQGPIILEKSIKIEEVIKIANTSIIDIVTKTVTPEIKAPYEL
                     VDVEYDKMGSDYILSILVDKEGGITVEDTSDLTNIISPLLDTIDPDPFPNQYMLEVSS
                     PGLERPLKTADSLKAAVGSYINVSLYQAIDKVKVFQGDLLAFDGETLTIDYLDKTRHK
                     IVNIPYQAVAKVRMAVKL"
     gene            complement(27446..27532)
                     /locus_tag="ACF4ZO_000136"
     tRNA            complement(27446..27532)
                     /locus_tag="ACF4ZO_000136"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(27496..27498),aa:Ser,seq:gga)
     gene            complement(27597..28232)
                     /gene="trmB"
                     /locus_tag="ACF4ZO_000137"
     CDS             complement(27597..28232)
                     /gene="trmB"
                     /locus_tag="ACF4ZO_000137"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008176 - tRNA
                     (guanine(46)-N7)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HFD5485723.1"
                     /translation="MRVRKRKGAEEHLANNPHYVILNPEDAKGRWHDVFGNDRPIHIE
                     VGSGKGGFITGMALKNPDINYIGIDIQLSVLSYALDKVLASEVSNVKLLRVDGSSLTN
                     YFEDGEVDMMYLNFSDPWPKTKHEKRRLTYKDFLDTYKRILPEHGEIHFKTDNRGLFE
                     YSLASFSQYGMTLRQIWLDLHASNYEGNVMTEYEEKFSNKGQVIYRVEANF"
     gene            complement(28232..29023)
                     /gene="ccrZ"
                     /locus_tag="ACF4ZO_000138"
     CDS             complement(28232..29023)
                     /gene="ccrZ"
                     /locus_tag="ACF4ZO_000138"
                     /EC_number="2.7.1.15"
                     /EC_number="2.7.1.229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004747 - ribokinase activity [Evidence
                     IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_function: GO:0019200 - carbohydrate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA];
                     GO_process: GO:0051726 - regulation of cell cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell cycle regulator CcrZ"
                     /protein_id="HFD5485724.1"
                     /translation="MTTTEQELTLTPLRGKSGKAYKGTYPNGECVFIKLNTTPILPAL
                     AKEQIAPQLLWAKRMGNGDMMSAQEWLNGRTLTKEDMNSKQIIHILLRLHKSKKLVNQ
                     LLQLNYKIENPYDLLVDFEQNAPLQIQQNSYLQAIVKELKRSLPEFKSEVATIVHGDI
                     KHSNWVITTSGMIFLVDWDSVRLTDRMYDVAYLLSHYIPRSRWSEWLSYYGYKNNDKV
                     MQKIIWYGQFSHLTQILKCFDKRDMEHVNQEIYALRKFREIFRKK"
     gene            complement(29087..30121)
                     /locus_tag="ACF4ZO_000139"
     CDS             complement(29087..30121)
                     /locus_tag="ACF4ZO_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD5485725.1"
                     /translation="MKALFLKRRQDFQKQQNKYLRYVLNDHFVLVLMFLLGFAMVQYG
                     QLLNHFPTNHLPIQVCLGILIPLLLSMGSIATYLEEADQHFLLPKEEEVISYIKQAER
                     LSFLLWGTLQTAVLLFLYPIFRRLGLSLLIFIILVLILLALKRVVLSRKTRYFLRGNR
                     LDWAKAVAFESNRKQSILKFYSLFTTVKGISTKVKERTYLNPLLKLVKQTPSNLWLSL
                     YARAFLRSSDYLGLFLRLMLLSSLSVFFIHNLYLSVSLALIFNYLVVFQLLSLYYHYD
                     YHYMTSLYPENSRSKKKNVLSFLRGLSFLMLIVNMLCCSSAPKALILIVGMVFIACIY
                     LPYKLKKIID"
     gene            complement(30124..30849)
                     /locus_tag="ACF4ZO_000140"
     CDS             complement(30124..30849)
                     /locus_tag="ACF4ZO_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD5485726.1"
                     /translation="MLNIKNLTGGYHNIPVLNDVSFSVDNGELVGLIGLNGAGKSTTI
                     NEIIGFLKPYQGSISIDGLTLAENAVAYRQKIGFIPETPSLYEELTLSEHINTVAMAY
                     DIDLEVAQKRAQPFLEMFRLTDKLEWFPVNFSKGMKQKVMIICAFVIDPSLFILDEPF
                     LGLDPLAISDLIQTLEVEKAKGKSILMSTHVLDSAERMCDRFVILHHGQVRAQGTLAD
                     LQEAFGDRSASLNDIYLALTKED"
     gene            30921..31340
                     /locus_tag="ACF4ZO_000141"
     CDS             30921..31340
                     /locus_tag="ACF4ZO_000141"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HFD5485727.1"
                     /translation="MENCIFCSIIQGDIPSSKVYEDEQVLAFLDISQTTKGHTLVIPK
                     QHVRNLLEMTAETASHLFARIPKIARAIQSATGATAMNIINNNEALAGQTVFHAHVHL
                     VPRYNEEDGISIQYTTHEPDFPVLEKLARQINQEVSS"
     gene            31337..31693
                     /locus_tag="ACF4ZO_000142"
     CDS             31337..31693
                     /locus_tag="ACF4ZO_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein"
                     /protein_id="HFD5485728.1"
                     /translation="MKVKTVIAVGLLSFTAYKAYQKRCTIKELLSISRQAKDAAQLDL
                     DNIKANLDLIHSQGKVIQNISQDLAHKWRYFNQETQAHLTEIQNRMAKYQEDSELISS
                     ESPTCQTVILTNNHSR"
     gene            complement(31804..33087)
                     /locus_tag="ACF4ZO_000143"
     CDS             complement(31804..33087)
                     /locus_tag="ACF4ZO_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070726 - cell wall assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HFD5485729.1"
                     /translation="MKIGKKIVLMFTAIVLTTVLALGVYLTSAYTFSTGELSKTFKDF
                     STSSKKSDAIKQTRAFSILLMGVDTGSSERASKWEGNSDSMILVTVNPKTKKTTMTSL
                     ERDTLTTLSGPKNNEMNGVEAKLNAAYAAGGAQMAIMTVQDLLNITIDNYVQINMQGL
                     IDLVNAVGGITVTNEFDFPISIAENEPEYQATVAPGTHKINGEQALVYARMRYDDPEG
                     DYGRQKRQREVIQKVLKKILALDSISSYRKILSAVSSNMQTNIEISSRTIPSLLGYRD
                     ALRTIKTYQLKGEDATLSDGGSYQIVTSNHLLEIQNRIRTELGLHKVSQLKTNATVYE
                     NLYGSTKSQTVNNNYDSSGQAPSYSDSHSSYANYSSGVDTGSSYQSTSTDQDSTASSH
                     TPTTPSSSSDALAADESSSSGSGSLVPPANINPQT"
     gene            complement(33096..33620)
                     /locus_tag="ACF4ZO_000144"
     CDS             complement(33096..33620)
                     /locus_tag="ACF4ZO_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HFD5485730.1"
                     /translation="MIQQSLVIEEGVPQDAKAVLSLVTAAAKETDFITGVETILEATP
                     QELSDFLSRSQTSFIDFCLLARLDEKVVGLLNLSGEVLSQGQVEADVFMLVAKTYRGY
                     GIGQLLLEIALDWAEENPYIESLKLDVQARNTKAIYLYKKYGFRIESMRKNDIKSKNG
                     DDLDVYHMRKSVSQ"
     gene            complement(33595..34056)
                     /gene="tsaE"
                     /locus_tag="ACF4ZO_000145"
     CDS             complement(33595..34056)
                     /gene="tsaE"
                     /locus_tag="ACF4ZO_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HFD5485731.1"
                     /translation="MFYSENEYTLKAYGETLGTYLSIGDVIVLSGDLGAGKTTLAKGI
                     AKGMGISQMIKSPTYTIVREYEGRLPLYHLDIYRVGDDPDSIDLDDFLFGNGVTVIEW
                     GELLGEGLLQDYLQITITKRDKGRQLDLLAHGERSRQLLEIISHDSAKSRY"
     gene            complement(34210..35670)
                     /locus_tag="ACF4ZO_000146"
     CDS             complement(34210..35670)
                     /locus_tag="ACF4ZO_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HFD5485732.1"
                     /translation="MEKFFKLSENGTTVSTEIMAGLTTFFAMSYILFVNPSILGAAGM
                     PSNAVFLATIIAAAISTLIMGLFANVPYALAPGMGLNAFFTYTVVFALGFSWQEALAM
                     VFICGLFNIFITVTKFRKSIIKAIPVSLQHAIGGGIGVFVAYLGFKNANIITFSISAE
                     NIVMVNGVEPAKASAKTFADGLLFVDANGGVVPTISSFTDSSVLLAIFGLLLTTALVI
                     RNFRGAILIGIVATTLVGIPLGIVDVSNLNFGISHIGEAWTELGTTFLAAFDGLSSLF
                     SDSSRLPLVFMTIFAFSLSDTFDTIGTFIGTGRRTGIFSQDDENALENSIGFSSKMDR
                     ALFADAIGTSIGALVGTSNTTTYVESAAGIAEGGRTGLTAVSTAVCFLLSILLLPLVG
                     IVPAAATAPALIVVGVMMVSSFLDVNWSKFADALPAFFAAFFMPLCYSISYGIAAAFI
                     FYCLVKVVEGKTKDIHPIIWGATFLFIVNFIILTIL"
     gene            35934..36746
                     /locus_tag="ACF4ZO_000147"
     CDS             35934..36746
                     /locus_tag="ACF4ZO_000147"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFD5485733.1"
                     /translation="MTKKLIAIDLDGTLLHHDNTISTYTQKTIKAVQDKGHHVIISTG
                     RPYRMALDYYLQLNLKTPIITFNGALTHMPEQKWAYEHNVTLDKGYLLRLLQYQDDFQ
                     MDFIASEYRKNVYITMTNPESIDPQLFGVDEITQDMALEITKITRNPNALLMQTRHED
                     KYALAKNMRAFFKDEIEIDSWGGPLNILEISSKNVNKAYALNYLLGIYNMDKKDLIAF
                     GDEHNDTEMLAFAGTGYAMKNASPVLLPYADQQLNFSNEEDGVAKKLEELFL"
     gene            37098..38090
                     /locus_tag="ACF4ZO_000148"
     CDS             37098..38090
                     /locus_tag="ACF4ZO_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFD5485734.1"
                     /translation="MGIGIIIASHGKFAEGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYGHFNNAIQQFDADDEILVLADLWSGSPFNQASRVAGENPDRKMAIITGLNLPMLIQ
                     AYTERLMDAGAGIEQVAANIIKESKDGIKALPEDLNPVEETAATEKVVNALQGAIPAG
                     TVIGDGKLKINLARVDTRLLHGQVATAWTPASKADRIIVASDEVAQDDLRKQLIKQAA
                     PGGVKANVVPISKLIEASKDPRFGNTHALILFQTPQDALRAVEGGVEINELNVGSMAH
                     STGKTMVNNVLSMDKEDVATFEKLRDLGVTFDVRKVPNDSKKNLFELIQKANIK"
     gene            38179..38988
                     /locus_tag="ACF4ZO_000149"
     CDS             38179..38988
                     /locus_tag="ACF4ZO_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0034219 - carbohydrate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HFD5485735.1"
                     /translation="MSDISIISAILVVIIAFFAGLEGILDQFQMHQPLVACTLIGLVT
                     GHLEAGVILGGTLQMLALGWANIGAAVAPDAALASVAAAIIMVKSGDFTQKGITFAYS
                     TAIPLAVAGLFLTMIVRTLSTALVHAGDKAAAEGNFAGIERFHFIALLLQGLRIAVPA
                     ALLVAVPTSAVQSVLNAMPNWLNEGMQIGGAMVVAVGYAMVINMMATREVWPFFALGF
                     ALAAISQLTLIAMGVIGVAIAFIYLNLSKKGGNGGNAAGSADPIGDILEDY"
     gene            39005..39916
                     /locus_tag="ACF4ZO_000150"
     CDS             39005..39916
                     /locus_tag="ACF4ZO_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000139230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFD5485736.1"
                     /translation="MTEQIKLTKSDRQRVWWRSQFLQGSWNYERMQNMGWAYALIPAL
                     RKLYTSPEDRAAALERHMEFFNTHPYVAAPIIGVTLALEEERANGTPIDDKAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGALGASLASTGNIVGPLLFFFGWNLIRMAFLWYTQE
                     FGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVSINFTIDLPGKQLSDGA
                     YVVFPDGAVKGAELKTILANAIGGMSLDKVQAQTLQGQLDSLIPGLAGLLLTFLCMWL
                     LKKKVSPIAIIIGLFAFGILAHLAGIM"
     gene            40030..40389
                     /locus_tag="ACF4ZO_000151"
     CDS             40030..40389
                     /locus_tag="ACF4ZO_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HFD5485737.1"
                     /translation="MAQSLNTSVEYKTKAVSYLGMGGKVGHILLGDKALEFYNDKNVN
                     DYIQIPWTAINHIGANVSRKKVSRHFEIFTDQGKFLFASGDSGKILKITRQHIGNEKV
                     ITLPTLMQTFINKFFRH"
     gene            40781..42058
                     /gene="serS"
                     /locus_tag="ACF4ZO_000152"
     CDS             40781..42058
                     /gene="serS"
                     /locus_tag="ACF4ZO_000152"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004828 - serine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006434 - seryl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HFD5485738.1"
                     /translation="MLDLKRIRTDFDTVAAKLKNRGVSEDTLTHLKELDEKRRTLLVQ
                     SEELKAERNIASAAIAQAKRQKEDATQQIADMQKVSADIKTIDNQLVAIDQQVADIIT
                     VLPNTPHDSVPVGADEEDNVEIRRWGTPRDFDFEVKAHWDLGEDLDILDWERGAKVTG
                     ARFLFYKNLGARLERALYNFMLDEHIKEGYQEIITPYMVNHDSMFGTGQYPKFKEDTF
                     ELADTNFVLIPTAEVPLTNYYRGEILDGKELPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYQELEKMTANAENILQKLGLPYRVISLCTGDMGFSAAKTY
                     DLEVWIPAQNTYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEVLRPYMGGETVISPK"
     gene            complement(42291..43061)
                     /locus_tag="ACF4ZO_000153"
     CDS             complement(42291..43061)
                     /locus_tag="ACF4ZO_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HFD5485739.1"
                     /translation="MTDVSRVLKEARDQGRLTTLDYANLIFDDFMELHGDRHFSDDGA
                     IVGGLAYLAGQPVTVIGIQKGKNLQDNLTRNFGQPNPEGYRKALRLMKQAEKFGRPVV
                     TFINTAGAYPGVGAEERGQGEAIAKNLMEMSDLKVPIIAIIIGEGGSGGALALAVADQ
                     VWMLENTMYAVLSPEGFASILWKDGSRATEAAELMKITAGELYQMGIVDRIIPEHGYF
                     SSEIVDIIKANLIEQITSLQAKPLDQLLDERYQRFRKY"
     gene            complement(43058..43924)
                     /gene="accD"
                     /locus_tag="ACF4ZO_000154"
     CDS             complement(43058..43924)
                     /gene="accD"
                     /locus_tag="ACF4ZO_000154"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase, carboxyltransferase
                     subunit beta"
                     /protein_id="HFD5485740.1"
                     /translation="MALFRKKDKYIRITPNNFLKGSVSHNVPEVPDELFAKCPACKHM
                     IYKKDLGLAKICPTCSYNFRISAQERLTLTVDEGSFQELFTSIETKDPLRFPGYQEKL
                     QKAKETTGLHEAVLTGKAMVKGQQIALAIMDSHFIMASMGTVVGEKITRLFELAIEEN
                     LPVVIFTASGGARMQEGIMSLMQMAKVSAAVKRHSNAGLFYLTILTDPTTGGVTASFA
                     MEGDIILAEPQSLVGFAGRRVIETTVRENLPDDFQKAEFLQDHGFVDAIVKRTELRDK
                     IAHLVAFHGGGQ"
     gene            complement(43933..45297)
                     /locus_tag="ACF4ZO_000155"
     CDS             complement(43933..45297)
                     /locus_tag="ACF4ZO_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HFD5485741.1"
                     /translation="MFKKILIANRGEIAVRIIRAARELGISTVAVYSEADKEALHTIL
                     ADEAICIGPARSKESYLNMNSVLSAAIVTGAQAIHPGFGFLSENSKFATMCEEMNIKF
                     IGPSASVMDKMGDKINARSEMIKAGVPVIPGSDGEVYNAQEALAIANKIGYPVMLKAS
                     AGGGGKGIRKVETEADLEAAFNAASQEALGAFGNGAMYLEKVIYPARHIEVQILGDAY
                     GNIIHLGERDCSLQRHNQKVLEESPSIAIGNTLRHEMGQAAVRAAKAVAYENAGTIEF
                     LLDEDSEKFYFMEMNTRIQVEHPVTEFVTGVDIVKEQIKIAAGQPLAINQEDITITGH
                     AIECRINAENTAFNFAPSPGKITDLYMPSGGVGLRVDSAVYNGYAIPPYYDSMIAKII
                     VHGSNRFDALMKMQRALVELEIEGIITNTDFQLDLISDKRVIAGDYDTSFLMETFLPH
                     YNKD"
     gene            complement(45329..45751)
                     /gene="fabZ"
                     /locus_tag="ACF4ZO_000156"
     CDS             complement(45329..45751)
                     /gene="fabZ"
                     /locus_tag="ACF4ZO_000156"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002922202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA];
                     GO_function: GO:0019171 -
                     (3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HFD5485742.1"
                     /translation="MMDIREIQAALPHRYPMLLVDRVLEVSDDHIVAIKNVTINEPFF
                     NGHFPHYPVMPGVLIMEALAQTAGVLELSKEENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFIKRRGTIAVVEARAEVDGKLAASGTLTFACGQ"
     gene            complement(45748..46248)
                     /gene="accB"
                     /locus_tag="ACF4ZO_000157"
     CDS             complement(45748..46248)
                     /gene="accB"
                     /locus_tag="ACF4ZO_000157"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HFD5485743.1"
                     /translation="MNIQEIKDLMAQFDTSSLREFLFKTNEGELIFSKNEQHLNASIS
                     NQEHAVPVPQVQLVPNSTASEASSPASVKDVPVEEQPQAESFVAEGDIVESPLVGVAY
                     LAASPDKPPFVAVGDTVKKGQTLVIIEAMKVMNEVPAPCDGVITEILVSNEDVIEFGQ
                     GLVRIK"
     gene            complement(46250..47482)
                     /gene="fabF"
                     /locus_tag="ACF4ZO_000158"
     CDS             complement(46250..47482)
                     /gene="fabF"
                     /locus_tag="ACF4ZO_000158"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HFD5485744.1"
                     /translation="MTFKRVVVTGYGLTSPIGHDPETFWNNLKAGQIGIGPITKFDTT
                     DYAVKNAAEIQDFPFDKYFVKKDLNRFDRYSLYALYAAKEAINHADLNIEMIDSDRFG
                     VIVASGIGGIAEIEEQVIRLHEKGPKRVKPMTLPKALPNMAAGNVAMSLKAQGVCKSI
                     NTACASSNDAIGDAFRAIKFGTQDVMIVGGSEAAITKFAIAGFQSLTALSTTEDPSRS
                     SIPFDKDRNGFIMGEGSGMLVLESLEHAQERGATILAEIVGYGNTCDAYHMTSPNPEG
                     LGARKAIHLALQEAGIEASAINYVNAHGTSTPANEKGESQAIVAVLGKDVPVSSTKSF
                     TGHLLGAAGAIEAIATIEAMRHNYVPMTAGTQALSEDIEANVIFGEGKETAINYAISN
                     TFGFGGHNAVLAFKCWEE"
     gene            complement(47497..48231)
                     /gene="fabG"
                     /locus_tag="ACF4ZO_000159"
     CDS             complement(47497..48231)
                     /gene="fabG"
                     /locus_tag="ACF4ZO_000159"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004316 - 3-oxoacyl-[acyl-carrier-protein]
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HFD5485745.1"
                     /translation="MEIKGKNIFITGSTRGIGLAMAHQFASLGANIVLNGRSAISEEL
                     VASFTDYGVTVVTISGDVSEASEAKRMVNEAIESLGSIDVLVNNAGITNDKLMLKMTE
                     EDFERVLKINLTGAFNMTQSVLKPMIKARQGAIINVSSVVGLTGNIGQANYAASKAGM
                     IGFTKSVAREVAARNICVNAIAPGFIESDMTGVLPEKMQEQILSQIPMKRIGKAQEVA
                     HLASFLVEQDYITGQVIAIDGGMTMQ"
     gene            complement(48221..49159)
                     /gene="fabD"
                     /locus_tag="ACF4ZO_000160"
     CDS             complement(48221..49159)
                     /gene="fabD"
                     /locus_tag="ACF4ZO_000160"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004314 - [acyl-carrier-protein]
                     S-malonyltransferase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HFD5485746.1"
                     /translation="MTKTAFLFAGQGAQKLGMARDFYDNFAIVRKTFDQASQVLGYDL
                     RRLIDSDELKLNQTSYTQPAILTSSIAIYRVLGLHHVKPDMVAGLSLGEYSALVASGA
                     LSFEDTLSLVAKRGRLMEEAAPQRSGKMVAVMNTDVQVIEEVCQIAAKHGVVAPANYN
                     APSQIVIGGQTDAVNVAVELLKERGVKRLIPLNVSGPFHTALLEPASRLLAKELERYN
                     FSDFKIPLVGNTEANIMEKDRIPELLARQVMEPVRFYDSVATLVESGITQFIEVGPGK
                     VLTGFVKKIDKNLLCTSVENMVSLRLFLDREDIHGN"
     gene            complement(49184..50155)
                     /gene="fabK"
                     /locus_tag="ACF4ZO_000161"
     CDS             complement(49184..50155)
                     /gene="fabK"
                     /locus_tag="ACF4ZO_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0018580 - nitronate monooxygenase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HFD5485747.1"
                     /translation="MKTRITELLNIDYPIFQGGMAWVADGDLAGAVSNAGGLGIIGGG
                     NAPKEVVKANIDRVKAITDRPFGVNIMLLSPFADDIVDLVIEEGVKVVTTGAGNPGKY
                     MERLHQAGIIVVPVVPSVALAKRMEKLGVDAVIAEGMEAGGHIGKLTTMSLVRQVVEA
                     VSIPVIAAGGIADGHGAAAAFMLGAEAVQIGTRFVVAKESNAHQNFKDKILAAKDIDT
                     VISAQVVGHPVRSIKNKLTSAYAKAEKAFLIGQKTATDIEEMGAGSLRHAVIEGDVVN
                     GSVMAGQIAGLVRKEESCETILKDIYYGAARVIQNEAKRWQSVSIEK"
     gene            complement(50356..50580)
                     /locus_tag="ACF4ZO_000162"
     CDS             complement(50356..50580)
                     /locus_tag="ACF4ZO_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000035 - acyl binding [Evidence IEA];
                     GO_function: GO:0000036 - acyl carrier activity [Evidence
                     IEA];
                     GO_process: GO:0009245 - lipid A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HFD5485748.1"
                     /translation="MAVFEKVQEIIVEELGKETEEVTLETTFDDLDADSLDVFQVISE
                     IEDAFDIQIETEEGLNTVGDLVAYVEEKSK"
     gene            complement(50641..51615)
                     /locus_tag="ACF4ZO_000163"
     CDS             complement(50641..51615)
                     /locus_tag="ACF4ZO_000163"
                     /EC_number="2.3.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0033818 -
                     beta-ketoacyl-acyl-carrier-protein synthase III activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase III"
                     /protein_id="HFD5485749.1"
                     /translation="MIFSKISQVAHYVPQQLVTNNDLASIMDTSHEWIFSRTGIAERH
                     ISRDEMTSDLAIQVADQLLTQSGLKANAIDFIIVATISPDATMPSTAAKVQAAIAATS
                     AFAFDMTAACSGFVFALAMADKLIASGAYQNGMVIGAETLSKLVNWQDRATAVLFGDG
                     AGGVLLEASKDKHVLAETLHTDGARCQSLISGETSLSSPYSIGKKAIATIQMDGRAIF
                     DFAIRDVSKSILTLMAQSDITKDDIDYCLLHQANRRILDKIARKIDVPREKFLENMMR
                     YGNTSAASIPILLSEAVQKGQIRLDGTQKILLSGFGGGLTWGSLIVKI"
     gene            complement(51616..52050)
                     /locus_tag="ACF4ZO_000164"
     CDS             complement(51616..52050)
                     /locus_tag="ACF4ZO_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFD5485750.1"
                     /translation="MEYDKINHYLVDIFNRILVIEEMSLKTSQFNDVSLKEMHTIEII
                     GKYDQVTPSDIARELMVTLGTVTTSLNKLEAKGYIARTRSRSDRRVVYLSLTKRGRLL
                     DRLHAKFHKNMVGHVIADMSDEEMQALVRGLGNLHQFLEDLV"
     gene            complement(52124..52915)
                     /locus_tag="ACF4ZO_000165"
     CDS             complement(52124..52915)
                     /locus_tag="ACF4ZO_000165"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HFD5485751.1"
                     /translation="MQFKHIIFDVVDDLAILTLNRPEVSNGFNIPICQEILVALAEVK
                     RDTSVRFLLIKAVGKVFSVGGDLVEMQEAVAKDNVQSLVKIAELVQEISFAIKHLPKP
                     VILCADGAVAGAAFNIALAVDFCIASTQTKFIQAFVNVGLAPDAGGLFLLTRAVGLNR
                     ATHLVMTGEGITADKGVDYGFVYRTAESDKLDKVCLQLLKRLRRGSSNSYAGMKSLVW
                     QSFFTGWEDYAKAELAIQEELAFKEDFKEGVIAFGERRRPNFQGK"
     gene            complement(53136..54272)
                     /gene="dnaJ"
                     /locus_tag="ACF4ZO_000166"
     CDS             complement(53136..54272)
                     /gene="dnaJ"
                     /locus_tag="ACF4ZO_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HFD5485752.1"
                     /translation="MNNTEYYDRLGVSKDASQDDIKKAYRKMSKKYHPDINKEAGAEQ
                     KYKDVQEAYETLSDSQKRAAYDQYGAAGAQGGFGGGAGGFGGFDGGGFGGFEDIFSSF
                     FGGGGSRNPNAPRQGDDLQYRVNLSFEEAVFGVEKEVSYNREATCGTCLGSGAKPGTA
                     PVTCRKCHGSGVMTIDTQTPLGMMRRQVTCDICHGSGKEIKEPCQTCHGTGHEKQAHK
                     VSVKIPAGVETGQQIRLQGQGEAGFNGGPYGDLFVILNVLPSKQFERNGSTIYYSLDI
                     SFTQAALGDTVEIPTVHGDVEMAIPAGTQTGKTFRLKGKGAPKLRGGGQGDQHVTVNI
                     VTPTKLNDAQREALQAFAEASGDKMLHPKKKGFFDKVKDALEDI"
     gene            complement(54553..56379)
                     /gene="dnaK"
                     /locus_tag="ACF4ZO_000167"
     CDS             complement(54553..56379)
                     /gene="dnaK"
                     /locus_tag="ACF4ZO_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HFD5485753.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPETVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGMDKTDK
                     DEKILVFDLGGGTFDVSILELGDGVFDVLATAGDNKLGGDDFDQKIIDFLVAEFKKEN
                     GIDLSQDKMALQRLKDAAEKAKKDLSGVTQTQISLPFITAGSAGPLHLEMSLSRAKFD
                     DLTRDLVERTKTPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQHIVIKSNDGLSEEEIDRMMKDAEANAEADAKRKEEVDLKNE
                     VDQAIFATEKTIKETEGKGFDTERDAAQSALDELKAAQESGNLDDMKAKLEALNEKAQ
                     ALAVKMYEQAAAAQQAAQGAEGAQANDSANNDDVVDGEFTEK"
     gene            complement(56560..57132)
                     /gene="grpE"
                     /locus_tag="ACF4ZO_000168"
     CDS             complement(56560..57132)
                     /gene="grpE"
                     /locus_tag="ACF4ZO_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HFD5485754.1"
                     /translation="MAVFNKLFKRRHSVSEEIKKDDLQEEVEATETEETVEEVIEETP
                     EKSELELANERADEFENKYLRAHAEMQNIQRRSSEERQQLQRYRSQDLAKAILPSLDN
                     LERALAVEGLTDDVKKGLEMTRDSLIQALKEEGVEEVEVDSFDHNFHMAVQTLPADDE
                     HPADSIAEVFQKGYKLHERLLRPAMVVVYN"
     gene            complement(57135..58169)
                     /gene="hrcA"
                     /locus_tag="ACF4ZO_000169"
     CDS             complement(57135..58169)
                     /gene="hrcA"
                     /locus_tag="ACF4ZO_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015911815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HFD5485755.1"
                     /translation="MITQRQNDILNLIVELFTQTHEPVGSKALQRTIDSSSATIRNDM
                     AKLEKLGLLEKAHTSSGRMPSPAGFKYFVEHSLRLDSIDEQDIYHVIKTFDFEAFKLE
                     DMLQKASHILAEMTGYTSVILDVEPARQRLTGFDVVQLSNHDALAVMTLDESKPVTVQ
                     FAIPRNFLTRDLIAFKAIVEERLLDSSVIDIHYKLRTEIPQIVQKYFVTTDNVLQLFD
                     YVFSELFLETVFVAGKVNSLTYSDLSTYQFLDNEQQVAISLRQSLKEGEMASVQVADS
                     QEAALADVSVLTHKFLIPYRGFGLLSLIGPIDMDYRRSVSLVNIIGKVLAAKLGDYYR
                     YLNSNHYEVH"
     gene            complement(58304..58873)
                     /locus_tag="ACF4ZO_000170"
     CDS             complement(58304..58873)
                     /locus_tag="ACF4ZO_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HFD5485756.1"
                     /translation="MRKRLKFPYFLTLLACFLLLIVCPLLSSQRIASADKEVRVNYSQ
                     KQFITKMGKEVKPLAKYYGIRPSILIAQILLETHDGKTLLASKYHNLFSKKATPGQAA
                     ITLKSPKQTNQNVRYAIYKDDASAIRDYLRMLRQGKEVDKRLYRNLATEKGYKAPAKS
                     LQKYLHYTDKTYARRLIQVIESNDLTNYD"
     gene            complement(58870..59613)
                     /locus_tag="ACF4ZO_000171"
     CDS             complement(58870..59613)
                     /locus_tag="ACF4ZO_000171"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HFD5485757.1"
                     /translation="MKHNHFKLLLQTLVVLLFVGGIYLFIKPEKQATKTPLSHQASSQ
                     KVVKNSKESTGLPKVSPKDWELILVNRDHMTEELSPELVDVNGVSVDKRIEQATADFL
                     AAAQAIDPQEHLISGYRSVAYQAELYQSYIKKEMPNDPTLTQEAAEALVQTYLQPPGA
                     SEHHTGLAIDMSTVDTLNASDPSVSKAVQKIAPDYGFVLRFPEGKKTSTGVDYEDWYY
                     RYVGKASARYMAQYNLTLEEYIAALKEKR"
     gene            complement(59603..60310)
                     /locus_tag="ACF4ZO_000172"
     CDS             complement(59603..60310)
                     /locus_tag="ACF4ZO_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HFD5485758.1"
                     /translation="MTKTRLYIARHGKTMFNTIGRAQGWSDTPLTKKGEEGIRELGLG
                     LKDATIPFKAAFSSDSGRTMQTIEIILRESENEFLPYTKDNRIREWCFGSLEGTYDSE
                     LFLGVLPRTKAFENRDNLRDVPYSELAESIVEVDTANWAEPWEVLRKRIWEGFEAIAL
                     SIQNAGGGNALVVSHGMTIGTFMWLIDPDREKQYIDNGSVTVVEFEDGQFTIKTIGDM
                     SYRYRGREIIEAMSDEA"
     gene            complement(60702..60941)
                     /locus_tag="ACF4ZO_000173"
     CDS             complement(60702..60941)
                     /locus_tag="ACF4ZO_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HFD5485759.1"
                     /translation="MIWSLIVGAFIGMIAGKMTEKSQSMGCFTNIIAGLIGSAVGQRL
                     FGDWGIQLAGMAIFPSILGAAIVIVLVSAIFGKRY"
     gene            complement(61159..61374)
                     /locus_tag="ACF4ZO_000174"
     CDS             complement(61159..61374)
                     /locus_tag="ACF4ZO_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5485760.1"
                     /translation="MIVADSNKLKYFVSEKKAVGLSQAAFLYVMLVTVYKKTIIYAKI
                     RLTGIALEPSGVSDGYLMNHRVCLHYY"
     gene            complement(61371..62810)
                     /gene="gatB"
                     /locus_tag="ACF4ZO_000175"
     CDS             complement(61371..62810)
                     /gene="gatB"
                     /locus_tag="ACF4ZO_000175"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016884 - carbon-nitrogen ligase activity,
                     with glutamine as amido-N-donor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HFD5485761.1"
                     /translation="MNFETIIGLEVHAELNTNSKIFSPSSAHFGEDPNANTNVIDWSF
                     PGVLPVMNKGVIDASIKAALALNMDIHKEMHFDRKNYFYPDNPKAYQISQFDEPVGYN
                     GWIEIKLEDGSTKKIRIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEIIQYTGISDVKMEEGSMRVDANISLRPYGQEQFGTKTELKNLNS
                     FSNVRKGLEFEVERQAKLLRSGGVIRQETRRYDEANKGTILMRVKEGAADYRYFPEPD
                     LPLYEIDDAWIDEMRAQLPQFPAQRRAKYEEELGLSAYDASQLTATKVLSDFFETAVS
                     LGGDAKQVSNWLQGEIAQFLNAEGKTIEEIALTPENLVEMIAIIADGTISSKMAKKVF
                     VHLAKNGGSARAYVEKAGLVQISDPAVLVPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVAQQLLAQELQKLRD"
     gene            complement(62810..64276)
                     /gene="gatA"
                     /locus_tag="ACF4ZO_000176"
     CDS             complement(62810..64276)
                     /gene="gatA"
                     /locus_tag="ACF4ZO_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HFD5485762.1"
                     /translation="MSFNHKTIEELHDLLVAKEISATELTQKTLEDIKSREEAVGSFI
                     TVSEEAALRQAAAIDAKGIDADNLMSGIPLAVKDNISTKGILTTAASKMLYNYEPIFD
                     ATSVANAYAKDMIVIGKTNMDEFAMGGSTETSYFKKTKNAWDHTKVPGGSSGGSATAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGVVGLKPTYGTVSRYGLIAFGSSLDQIGPFAPTV
                     KENAQLLNVIASSDVKDATSAPVRIADYTSKIGRDIKGMKIALPKEYLGEGIDPEIKE
                     TVLAAAKQFEALGATVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGFRADDA
                     KNLDEIYVNTRSQGFGDEVKRRIMLGTFSLSSGYYDAYFKKAGQVRTLIIQDFDKVFA
                     DYDLILGPTTPTVAFGLDTLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFVDGLPVG
                     LQLIGPKYAEETIYQAAAAFEAVTDYHKQQPIIFGGDK"
     gene            complement(64276..64578)
                     /gene="gatC"
                     /locus_tag="ACF4ZO_000177"
     CDS             complement(64276..64578)
                     /gene="gatC"
                     /locus_tag="ACF4ZO_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA];
                     GO_process: GO:0006450 - regulation of translational
                     fidelity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HFD5485763.1"
                     /translation="MKISEEEVRHVAKLSKLSFSESETTTFATTLSKIVDMVELLNEV
                     DTEGVAITTTMADKKNVMRQDVAEEGTDRALLFKNVPEKENHFIKVPAILDDGGDA"
     gene            complement(64810..65073)
                     /locus_tag="ACF4ZO_000178"
     CDS             complement(64810..65073)
                     /locus_tag="ACF4ZO_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016772 - transferase activity,
                     transferring phosphorus-containing groups [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative PEP-binding protein"
                     /protein_id="HFD5485764.1"
                     /translation="MTGVFLIRTRSRPLIRKGLAVSLARSVKPDLKLGICGEHGGDPA
                     SIAFCHSQGLTYVSCSPFRVPLTRLAAAQAAIKASGHSLTQDK"
     gene            complement(65572..66126)
                     /locus_tag="ACF4ZO_000179"
     CDS             complement(65572..66126)
                     /locus_tag="ACF4ZO_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase family protein"
                     /protein_id="HFD5485765.1"
                     /translation="MRALISIDYTNDFVADDGKLSAGKSAQAIATKIAEVTKTAFDQG
                     DYIFFAIDCHDQNDSWHPESKLFAAHNIKGTTGRHLYGPLAEVYSYMKQHPRVFWIDK
                     RYYSAFSGTDLDIRLRERGITQLVLTGVLSDICVLHTAIDAYHLGYQLEIVKSAVASL
                     TKESYEWSLAHFEQVLGAKLINDY"
     gene            complement(66273..67055)
                     /gene="codY"
                     /locus_tag="ACF4ZO_000180"
     CDS             complement(66273..67055)
                     /gene="codY"
                     /locus_tag="ACF4ZO_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HFD5485766.1"
                     /translation="MPNLLEKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNAC
                     IINGGGTLLGYAMKYKTNTDRVEEFFEAKQFPDTYVKAASRVYDTEANLSVENELTIF
                     PVESKDTYPGGLTTIAPIYGGGMRLGSLIIWRNDNEFSDDDLILVEISSTVVGIQLLN
                     LQTENLEDTIRKQTAVNMAINTLSYSEMKAVAAILGELDGNEGRLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVINEGIFAKLKEF"
     gene            complement(67273..68487)
                     /locus_tag="ACF4ZO_000181"
     CDS             complement(67273..68487)
                     /locus_tag="ACF4ZO_000181"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HFD5485767.1"
                     /translation="MKIIEKSSKLEHVAYDIRGPVLDEANRMIASGEKILRLNTGNPA
                     AFGFEAPDEVIRDLIVNARLSEGYSDSKGIFSARKAIMQYCQLKGFPDVDIEDIYLGN
                     GVSELISMSLQALLDNGDEVLVPMPDYPLWTACVSLGGGKAVHYLCDEEAGWYPDIAD
                     IKSKITSRTKAIVVINPNNPTGALYPKEILEDIVALAREHQLIIFADEIYDRLVMDGK
                     EHIAIASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKDHVKGYIEGLNMLANMRL
                     CSNVLAQQVVQTSLGGHQSVDALLLPGGRIFEQRNFIYEAINAIPGLSAVKPEAGLYL
                     FPKIDRQMYRIDDDEEFVLQLLKQEKVMLVHGRGFNWKDPDHFRIVYLPSVEELEDVQ
                     EKITRVLYQYRR"
     gene            68718..69170
                     /locus_tag="ACF4ZO_000182"
     CDS             68718..69170
                     /locus_tag="ACF4ZO_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015055992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HFD5485768.1"
                     /translation="MSLKYKRILVAIDGSYESELAFNKGVNVALRNDATLLLVHVIDT
                     RALQSVATFDTYIYEKLEQEAKDVLDDFEKQAQIAGITNTKQIIEFGNPKNLLAHDIP
                     DRENADLIMVGATGLNTFERLLIGSSSEYIMRHAKIDLLVVRDSTKTL"
     gene            complement(69293..70681)
                     /locus_tag="ACF4ZO_000183"
     CDS             complement(69293..70681)
                     /locus_tag="ACF4ZO_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFD5485769.1"
                     /translation="MTVKAVFFDIDGTLLNDRKNIQKTTQKAIQQLKKQGIMVGLATG
                     RGPGFVQPFLENFGLDFAVTYNGQYILTRDKVLYQNQLPKSMIYKVIRYANEKKREIS
                     LGTASGLAGSRIIDMGTSPFGQVISSFVPKSWARTVEGSFKHLIRRIKPQSFRNLVTI
                     MREPIYQVVLVASQAETKKIQEKFPHIKITRSSPYSLDLISVDQSKIKGIERLGEMFG
                     FDLSEVMAFGDSDNDLEMLSGVGIGIAMGNAETVVKDGAHFTTDSNNNDGISKALAHY
                     GLIHFDIEKSFKSRDENFNKVKDFHRLMDSDTIETPRSYTISEAGYRSGFKVEEIVEF
                     LYAASKGDQQQFTQAIFDLHGAVDQAANKVQAKKHVETPLIGQVDALADLLYFTYGSF
                     VLMGVDPQPIFEAVHEANMAKIFPDGKAHFDPVTHKIQKPDYWQERHAPEVAIKKELD
                     KQLQKSLQRFDK"
     gene            70753..71718
                     /locus_tag="ACF4ZO_000184"
     CDS             70753..71718
                     /locus_tag="ACF4ZO_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017643115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HFD5485770.1"
                     /translation="MKKILVLHTGGTISMQADNSGRVVPNQDNPMTKIHAAAQNIQLT
                     VSDFLNLPSPHITPHHMLSIYHHIQERTDVFDGIVITHGTDTLEETAYFLDTMALPTN
                     IPVVLTGAMRSSNEVGSDGIYNYLTALRVASSDKAKEKGVLVVMNDEIHAAKYVTKTH
                     TTNISTFQTPTHGPLGIIMKNDLLFFKTAEPRIRFDLRCISGTIPIIKAYAGMGDGSI
                     LSLLTPGSIQGLVIEALGAGNVPPLAVGEIEHLITLGIPIVLVSRCFNGMAEPVYAYE
                     GGGAMLQEAGVMFVKELNAPKARLKLLIALNAGLTGQELKDYIEG"
     gene            complement(72067..72771)
                     /locus_tag="ACF4ZO_000185"
     CDS             complement(72067..72771)
                     /locus_tag="ACF4ZO_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD5485771.1"
                     /translation="MISYLKADLFRIRQERLALFSCMLLVVIAVGVAYSFRKTPNQVI
                     MIQIINIITDFVTLFFLTPARIFFSDDYNYRTINNVVVKQQNRTLIIIYKLLVSFGLS
                     LLFISLTYLLSALAFHLFTGQAYYGIVIDRMIKQLPFYIAIIALCQFLFNILRKTYQS
                     ITAYILYVLLFDKVSATLANHFFKLDISPVLMFKHLSLSLGDKHLSSTSILVAFGLTL
                     CYLLGNVFLFSKRELK"
     gene            complement(72784..73686)
                     /locus_tag="ACF4ZO_000186"
     CDS             complement(72784..73686)
                     /locus_tag="ACF4ZO_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFD5485772.1"
                     /translation="MTQQSMLLSIEQVNKSYGKNQVLSDISFDIYKGEICGLVGQNGA
                     GKTTLMRILSGLIGKDSGQIKQLQPYRMGSIIESPTLYPNMTAHDNLYYAALQLRLAD
                     AKERIHEVLELIGLEKVSKKKKVKDYSLGMRQRLAVGLSILDFPEFLILDEPINGLDP
                     AGIKEMRQIILNLRDCYGITILISSHILSELDLVVDRYVIMHKGKVIKSMDKAELKAQ
                     VKVQIALHTSDDQLVKNRLLELGLRVETDGQMLLIKPTLSVMELIKIVLDLPVEIFDI
                     YHHQVSFEHYYLDLLGKDAASPLI"
     gene            complement(73978..75993)
                     /gene="recG"
                     /locus_tag="ACF4ZO_000187"
     CDS             complement(73978..75993)
                     /gene="recG"
                     /locus_tag="ACF4ZO_000187"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019805675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HFD5485773.1"
                     /translation="MILTAPMSNLKGFGPKSAEKFQKLDIYTVEDLLLYYPFRYEDFK
                     SKSVFDLVDGEKAVITGLVVTPANVQYYGFKRNRLSFKLRQGEAVLNVSFFNQPYLAD
                     KIELGQEVAVFGKWDATKSAITGMKVLAQVEDDMQPVYRVAQGISQSTLIKAIKSAFE
                     IDAHLELKENLPATLLEKYRLMGRSQACLAMHFPKDITEYKQALRRIKFEELFYFQMN
                     LQVLKAENRSETNGLPILYSKHAMETKISSLPFILTNAQKRSLDDILSDMSSGAHMNR
                     LLQGDVGSGKTVIASLSMYAAYTAGFQSALMVPTEILAEQHYISLQELFPDLSIAILT
                     SGMKAAVKRTVLAAIANGSVDMIVGTHALIQDSVQYHKLGLVITDEQHRFGVKQRRIF
                     REKGENPDVLMMTATPIPRTLAITAFGEMDVSVIDELPAGRKPIMTRWVKHEQLGTVL
                     EWVKGELQKDAQVYVISPLIEESEALDLKNAVALHAELSTYFEGIAKVALVHGRMKND
                     EKDAIMQDFKDKKSHILVSTTVIEVGVNVPNATIMIIMDADRFGLSQLHQLRGRVGRG
                     HKQSYAVLVANPKTDSGKKRMTIMTETTDGFVLAESDLKMRGSGEIFGTRQSGIPEFQ
                     VADIVEDYPILEEARKVSAAIVSDPNWIYEKQWQLVAKNIRKKEVYD"
     gene            complement(76368..77822)
                     /locus_tag="ACF4ZO_000188"
     CDS             complement(76368..77822)
                     /locus_tag="ACF4ZO_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD5485774.1"
                     /translation="MERLGGADLDYCYHNHHDTSMISAEQLVFTYHDQKNPACQVPTC
                     QIASGQFIVLCGPSGSGKSTFLKLLNGIIPDYYAGKYEGRLDVADCQAGRDSVETFSR
                     SVASVFQNPASQFFYREVQHELVFPCENQGLDAKVIMKRLWTLAEDFAFAELLNKDMF
                     GLSGGQKQRVAIATAIMQGTNIMLFDEPTANLDSAGIAAIKAYLTQLKAAGKTIIVAE
                     HRLHYLMDLADNFFYFKNGRLTDKLTTQNLLALTDEQRQDMGLRRLDLSDLKPVLAGK
                     IESQHYRPDDSLCIEHLTVRAGSKILRCIEQLSFAAGSISGITGSNGLGKSQLVYYIA
                     GILDDKKATIKFQGIPLSAKQRLSKTSIVLQEVSLQLFAESVSKEVNLGHERHPRTTE
                     VIERLSLTTLLERHPASLSGGEQQRVMIAASLLADKDILIFDEPSSGLDLLQMKALAN
                     LLMQLKTQHKVVILISHDEELLSSVCDTIYQMLP"
     gene            complement(77759..78439)
                     /locus_tag="ACF4ZO_000189"
     CDS             complement(77759..78439)
                     /locus_tag="ACF4ZO_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     component T"
                     /protein_id="HFD5485775.1"
                     /translation="MRLDVRTKLLLLVLANACFFFRVDGFLEFIIVIFLLLLLSALNK
                     KKLAFKLAVVYLLMIGLSVIPLSIFPSYLDHLLSFVSIAGRLVFPSLLAGLITIKTTT
                     IYELVHGLRKWHFPEVWLLTLAVMCRFIPMIRQECCVIHRSLTIRGIILTKWSILIRP
                     KQYLEYLMVPLLLSLIRSSQELTIASLTKGLAVNKGTSECFSSHLTWKDWGVQIWITV
                     IIIITILQ"
     gene            complement(78436..79029)
                     /locus_tag="ACF4ZO_000190"
     CDS             complement(78436..79029)
                     /locus_tag="ACF4ZO_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HFD5485776.1"
                     /translation="MKQLTIKDIMITGAFAALYFICVGLGTFINIFFDRSGNMLYAPA
                     FAALLGGTIYFLLIAKLQTFGPITLLGLMMGGFFFLSGHFFAAMFPSIIFGLIADIIA
                     SLGKYKSRFFNDLSYMVFAFVNSGPILLMWLLKDAYVESLLARGKSMTYVNRIMYDFS
                     LGHVIWFVGIVLAGALLGSAFAHYLLKKHFIKSGLLS"
     gene            complement(79026..80696)
                     /locus_tag="ACF4ZO_000191"
     CDS             complement(79026..80696)
                     /locus_tag="ACF4ZO_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding/permease
                     protein"
                     /protein_id="HFD5485777.1"
                     /translation="MAKPNRSTLSLVWRLLTLMKTLLPWIILAVGFAVMGFVITVSIP
                     TGIAYLGLLAIRQEVIPILALYLLIALAFLRGFVRYGEHYFGHFVAFHSLAAFRNLIF
                     KKLRALSPACLDSQDSGYLLKMIGEDIEALEVFFAHTIAPICTAILSAGLMFWYFCQS
                     SWQLALLALATYACLAIVIPIYFANILQVLLKSQNEGRKDYLSYFLESLRSVKDLLQF
                     QVLDEQFERLIKKSNHVNALDRNVAQAQFLQMALTFFWLGLMILAFSYMVFDGICHDS
                     LSFDKGLLTFIAFTASFSPFLELGRLPLGFKRAMNAARNIFDLLDENVIVDEGTKQID
                     RLRSVSFEDLSFAYPKRQELVFKDLTVTFQEKGIIGIKGESGSGKSTLVKLIMKWYNW
                     KTGDIFLNDRNSCLLNAAKLQDTIAYVPQTAQLFQQSIRENLTFGRQDISDESIWNLA
                     EACGMKDRLLACKEGLDTIIKSPSDFSAGEGQRLELMRALLKDASCYIFDEPTSNLDS
                     LNEAILLDLIKTHCQGLVFLISHRPSTLACADHLFCVKNGFLKEVNKK"
     gene            complement(80689..82452)
                     /locus_tag="ACF4ZO_000192"
     CDS             complement(80689..82452)
                     /locus_tag="ACF4ZO_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
                     /protein_id="HFD5485778.1"
                     /translation="MMETEDTISRGKRKRLLKRLRERIAPKRYLLYVSAFLSWLQFVM
                     RMISFYLIAKTFSTFILGHAIALGRLAGLLLLLNVVGFVLAILGKQLQGIASQFARDS
                     LKQSFFEAFIDLDGQFDAHASDADILTLASQGIDSLDTYYGYYLSLSMRTKWNCTTIM
                     ILVFLIYPLAGLVFLGVLPLIPLSIVAMQKRSKQIMSHYWSSYMDVGNLFMDDLKGLN
                     TLYSYQATGRYEQEFSGKAEQFRKATMSLLGFQLQAVGYMDAVMYLGIGLSGFLAVQA
                     LATGQLSFFNFLFFLLIATEFFTPIREQGYGMHLVMMNTKMADRIFSFLDSVPARKDN
                     KSKTAINFNQIDIQNISLAYEKKTVLSGVTMTLTKGQLTAIAGVSGQGKTSLAQLLLK
                     RQSATTGHILFDGLDSDNLSQETINQQVLYVSDQSTLLNRSIYDNLRLAANLSKKEIL
                     DWIDQHGLLSFINWLPDGLDTIVGENGNLLSPGQKQQVICARALLSKRSLYIFDEATS
                     SLDAENERIIDNLITRLAKTAIVIVITHKMSRLKGANQVLFLNTGQPACLGKPCDLYR
                     DQPTYRHLVDTQARLEASIYG"
     gene            complement(82449..83285)
                     /locus_tag="ACF4ZO_000193"
     CDS             complement(82449..83285)
                     /locus_tag="ACF4ZO_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD5485779.1"
                     /translation="MSKNSSHIQVQNLSFAYEEKLVLDDLTFSIPKGKITTIMGANGS
                     GKSTLLQLLTKNLPLKQGQVWLEQEELATISLKAFAKKVAVVHQYHQVVEGLLVGELV
                     AMARLARRSFFKTTTKEDEEHLAWALEVTALSDYVYRDIQHLSGGEQQRVWIAMALAQ
                     DTDIIFLDEPTTYLDIKYQLDILTLITKINQELGLTIVLVLHDINQALSLSDHLIGLK
                     NGRLYAQGQPRDLLDQQFIRDVFGVELPFVERNGQQFVLTSLVNETNDIRTQRRDRNK
                     NR"
     gene            complement(83282..84304)
                     /locus_tag="ACF4ZO_000194"
     CDS             complement(83282..84304)
                     /locus_tag="ACF4ZO_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecCD family ABC transporter permease"
                     /protein_id="HFD5485780.1"
                     /translation="MTASDLQRDQSLLAKKRFRSGLYLVLLILSLLFLAVIALSLGGL
                     AVSYGAIVKGLFVAYDPQVALIYDLRFPRIVIALLAGAGIAVSGVLFQAVLKNPISDP
                     AIIGICSGASFMVLVSSLLLPQLLLYGPIVSFLGGGVSFLLIYGLAWKKGLNPIRLIL
                     TGIAINALFMGLSTALTSFFTSASPMVNALLAGHISQKTWADVGVLFPYTFIGLLLAL
                     LLSKTCNLLLLDDQVIRHLGIDATALRLGISLVAVLLASVATSIVGVVSFLGLIVPHM
                     SRLLVGSKHQILIPFSALLGAFVFLLADTLGRSLAYPLEISPAIIMSIVGGPYFIYLL
                     RRSDII"
     gene            complement(84306..85190)
                     /gene="isdE"
                     /locus_tag="ACF4ZO_000195"
     CDS             complement(84306..85190)
                     /gene="isdE"
                     /locus_tag="ACF4ZO_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA];
                     GO_process: GO:0015886 - heme transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heme ABC transporter substrate-binding protein
                     IsdE"
                     /protein_id="HFD5485781.1"
                     /translation="MIKRCKGIGLVLMAFFLVACVNQHPKTAKETEQQRIVATSVAVV
                     DICDRLNLDLVGVCDSKLYTLPKRYDAVKRVGLPMNPDIELIASLKPTWILSPNSLQE
                     DLEPKYQKLDTEYGFLNLRSVEGMYQSIDDLGNLFQRQQEAKELRQQYQDYYRAFQAK
                     RKGKKKPKVLILMGLPGSYLVATNQSYVGNLLDLAGGENVYQSDEKEFLSANPEDMLA
                     KEPDLILRTAHAIPDKVKVMFDKEFAENDIWKHFTAVKEGKVYDLDNTLFGMSAKLNY
                     PEALDTLTQLFDRVGDHP"
     gene            complement(85191..86048)
                     /locus_tag="ACF4ZO_000196"
                     /pseudo
     CDS             complement(85191..86048)
                     /locus_tag="ACF4ZO_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407805.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0020037 - heme binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="heme-binding Shp domain-containing protein"
     gene            complement(86245..90072)
                     /gene="shr"
                     /locus_tag="ACF4ZO_000197"
     CDS             complement(86245..90072)
                     /gene="shr"
                     /locus_tag="ACF4ZO_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme-binding protein Shr"
                     /protein_id="HFD5485782.1"
                     /translation="MKKISKCAFVAISALVLIQATQTVKSQEPLVQSQLVTTVALTQD
                     NRLLVEEIGPYASQSAGKEYYKHIEKVIVDNDVYEKSLEGERTFDINYQGIKINANLI
                     KDGKHELTIVNKKDGDILITFIKKGDKVTFISAQKLGTTDHQDSLKKDVLSDKTVPQN
                     QGTQKVVKSGKNTANLSLITKLSQEDGAILFPEIDRYSDNKQIKALTQQITKVTVNGT
                     VYKDLISDSVKDTNGWVSNMTGLHLGTKAFKDGENTIVISSKGFEDVTITVTKKDGQI
                     HFVSAKQKQHVTAEDRQSTKLDVTTLEKAIKEADAIIAKESNKDAVKDLAEKLQVIKD
                     SYKEIKDSKLLDDTHRLLKDTIESYQAGEVSINNLTEGTYTLNFKANKENSEESSMLQ
                     GAFDKRAKLVVKADGTMEISMLNTALGQFLIDFSIESKGTYPAAVRKQVGQKDINGSY
                     IRSEFTMPIDDLDKLHKGAVLVSAMGGQESDLNHYDKYTKLDMTFSKTVTKGWSGYQV
                     ETDDKEKGVGTERLEKVLVKLGKDLDGDGKLSKTELEQIRGELRLDHYELTDISLLKH
                     AKNITELHLDGNQITEIPKELFSQMKQLRFLNLRSNHLTYLDKDTFKSNAQLRELYLS
                     SNFIHSLEGGLFQSLHHLEQLDLSKNRIGRLCDNPFEGLSRLTSLGFAENSLEEIPEK
                     ALEPLTSLNFIDLSQNNLALLPKTIEKLRALSTIVASRNHITRIDNISFKNLPKLSVL
                     DLSTNEISNLPNGIFKQNNQLTKLDFFNNLLTQVEESVFPDVETLNLDVKFNQIKSVS
                     PKVRALIGQHKLTPQKHIAKLEASLDGEKIKYHQAFSLLDLYYWEQKTNSAIDKELVS
                     IEEYQQLLQEKGSDTVSLLNDMQVDWSIVIQLQKKASNGQYVTVNEKLLSNDPKDDLT
                     GEFSLKDPGTYRIRKALITKKFATQKEHIYLTSNDILVAKGPHSHQKDLVENGLRALN
                     QKQLRDGIYYLNASMLKTDLASESMSNKAINHRVTLVVKKGVPYLEVEFRGIKVGKML
                     GYLGELSYFVDGYQRDLAGKLVGRTKKAEVVSYFTDVTGLPLADRYGKNYPKVLRMKL
                     IEQAKKDGLVPLQVFVPIMDAISKGSGLQTVFMRLDWASLTTEKAKVVKETNNPQENS
                     HLTSTDQLKGPQNRQQEKTPTSPPSAATGIANLTDLLAKKATGQSTQETSKTDDTDKA
                     EKLKQLVRDHQTSIEGKTAKDTKTKKSDKKHRSNQQSNGEESSSRYHLIAGLSSFMIV
                     ALGFIIGRKTLFK"
     gene            complement(90563..92074)
                     /locus_tag="ACF4ZO_000198"
     CDS             complement(90563..92074)
                     /locus_tag="ACF4ZO_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HFD5485783.1"
                     /translation="MNKNKLLRVAMLLSLLAPTAESMTVLAQDVMLETHKATTNETSD
                     SSSKEENNKNAAPTTSDKTDQGPLDASAETNSNSLVNADDKKRSDSSQSAVGSSDNKA
                     EAENQVDDKSTDHSKPTDQPKPTDQPKPSPSKVDTAPASSLSRQLPEVRTPIQSLSPY
                     VSDLDLSEIDIPSVNTYAAYVEHWSGKNAYTHHLLSRRYGIKADQIDSYLKSTGIAYD
                     STRINGEKLLQWEKKSGLDVRAIVAIAISESSLGTQGIATLLGANMFGYAAFDLDPTQ
                     ASKFNDDSAIVKMTQDTIIKNKNSNFALQDLKAAKFSRGQLNFASDGGVYFTDTTGSG
                     KRRAQIMEDLDKWIDDHGGTPVIPAELKVQSSASFASVPAGYKLSKSYDVLGYQASSY
                     AWGQCTWYVYNRAKELGYQFDPFMGNGGDWKYKAGYALSKTPKVGYAISFAPGQAGAD
                     GTYGHVSIVEDVRKDGSILISESNCIGLGKISYRTFTAQQAEQLTYVIGKSKN"
     gene            complement(92161..93261)
                     /gene="alr"
                     /locus_tag="ACF4ZO_000199"
     CDS             complement(92161..93261)
                     /gene="alr"
                     /locus_tag="ACF4ZO_000199"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008784 - alanine racemase activity
                     [Evidence IEA];
                     GO_process: GO:0006522 - alanine metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HFD5485784.1"
                     /translation="MISSFHRPTVARVNLQAIKENVASVQKHIPLGVKTYAVVKADAY
                     GHGAVQVSKALLPQVDGYCVSNLDEALQLRQAGIDKEILILGVLLPNELKLAITRQVT
                     VTVASLEWLAMAKQEWPDLKGLKVHIKIDSGMGRIGLRSVTEVDNLIAGLKSMGADVE
                     GIFTHFATADEADDTKFNQQLQFFKKLIAGLEDKPRLVHASNSATSIWHSDTIFNAVR
                     LGIVSYGLNPSGSDLSLPFPLQEALSLESSLVHVKMISAGDTVGYGATYTAKKSEYVG
                     TVPIGYADGWTRNMQGFSVLVDGQFCEIIGRVSMDQLTIRLSKAYPLGTKVTLIGSNQ
                     QKNISTTDIANYRNTINYEVLCLLSDRIPRIY"
     gene            complement(93258..93614)
                     /gene="acpS"
                     /locus_tag="ACF4ZO_000200"
     CDS             complement(93258..93614)
                     /gene="acpS"
                     /locus_tag="ACF4ZO_000200"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008897 - holo-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HFD5485785.1"
                     /translation="MIVGHGIDLQEISAIEKVYQRNPRFAQKILTEQELAIFESFPYK
                     RRLSYLAGRWSGKEAFAKAIGTGIGRLTFQDIEILNDVRGCPILTKSPFKGNSFISIS
                     HSGNYVQASVILEDKK"
     gene            complement(93730..96249)
                     /gene="secA"
                     /locus_tag="ACF4ZO_000201"
     CDS             complement(93730..96249)
                     /gene="secA"
                     /locus_tag="ACF4ZO_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HFD5485786.1"
                     /translation="MANILRKVIENDKGELRKLEKIAKKVESYADQMASLSDRDLQGK
                     TLEFKERYQKGETLEQLLPEAFAVVREAAKRVLGLFPYRVQIMGGIVLHNGDVPEMRT
                     GEGKTLTATMPVYLNAIAGEGVHVITVNEYLSTRDATEMGEVYSWLGLSVGINLAAKS
                     PAEKREAYNCDITYSTNSEVGFDYLRDNMVVRQEDMVQRPLNFALVDEVDSVLIDEAR
                     TPLIVSGAVSSETNQLYIRADMFVKTLTSVDYVIDVPTKTIGLSDSGIDKAESYFNLS
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEDGEILIVDQFTGRTMEGRRFSDGL
                     HQAIEAKEGVRIQEESKTSASITYQNMFRMYKKLAGMTGTAKTEEEEFREVYNMRIIP
                     IPTNRPIARIDHTDLLYPTLESKFRAVVEDVKTRHAKGQPILVGTVAVETSDLISRKL
                     VEAGIPHEVLNAKNHFKEAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMRRFGSDRIKAFLDRMKLDE
                     EDTVIKSGMLGRQVESAQKRVEGNNYDTRKQVLQYDDVMREQREIIYANRRDVITANR
                     DLGPEIKAMIKRTIDRAVDAHARSNRKDAIDAIVTFARTSLVPEESISAKELRGLKDD
                     QIKEKLYQRALAIYDQQLSKLRDQEAIIEFQKVLILMIVDNKWTEHIDALDQLRNAVG
                     LRGYAQNNPVVEYQAEGFKMFQDMIGAIEFDVTRTMMKAQIHEQERERASQRATTAAP
                     QNIQSQQSANTDDLPKVERNEACPCGSGKKFKNCHGRKSFS"
BASE COUNT        29333 a        20691 c        16728 g        29599 t
ORIGIN      
        1 tcaaggtgtg aacaggacga atgtattcaa aactattgtt agcccagtgc atgctgactg
       61 ggaaggtcat tgctgacaac acttcagtaa cgcctagaag cacttcctta gcaggttttc
      121 cagcttcgtg tttggtcaca taaacgtatt cttctccttt gacttcgcgg aattcgatag
      181 catctgtggt caagcctttg ccacgaacaa atccttgagc agcttttgag aaattcccat
      241 cagcatcaag ggcaattttc ttagcaggcc ctttaaagtc ctcagtcaaa tccgtttgct
      301 gagcagctaa cccagacaca cgcactgcca aacggcgtgg agttgaaaag gtttgtatat
      361 cttcaaaaga gagacgattt tctgttaaga aagtcgccag gcgctctccc agttgttttt
      421 cacttggtgt gaccacgtag gctggaagtt cttccagacc aagttcgatt agtagatttt
      481 tactcataat taagatacca agggcgttaa gtggacacca tcaaaatagc aaagcgacgc
      541 aggtgcttgc acctaggaag tcttggtctt tttgacatag tccgtagccc gtgttcagtt
      601 cctttctcta aaaagtatct ttttgattgt tcccttaggt aggggggacg caaagtgaaa
      661 ttatccagtg gataatttca gaaaacaaaa gtgttccatt cctagttagc cagcctaaag
      721 tctcgccaac tccctcgttc gataagtaac cttgccgaat tgtcactaca gcgggagtaa
      781 ccttgactcg gcgaccttcg gtctcccact tcttgctcgc tcttaagatt acaaagctcg
      841 caactagatc atctttaaat cgacttattc gtcatcttca gctagcaaga ttgcgcgtgt
      901 tgcttcatcc aacagtggaa atccaagctt cttgcgttct gcaacaaagg tcttagcaac
      961 gacacgtgcc aaattacgga tacgagcaat gtagcctgcg cgttctgtga cggaaacagc
     1021 gccacgggca tccagcaggt taaacgtatg agaacatttg agcacgtaat cataagctgg
     1081 gtgaaccaaa ccttcttcta gggcacgcga ggcttctttt tcaaactttt caaagttttc
     1141 aagcagcatg tcttggtctg acatttcaaa ggaatatttt gaatgctcat actcaggttg
     1201 caagaagatt tcaccatatt taacacctgg tgcccactca atatcataga ccgaatccac
     1261 ttcttgaata taggaagcta agcgctcaag accataagtt acttctgctg tcactggaga
     1321 tgtcgcaagg ccaccaactt gttggaaata cgtaaattgt gtgatttcca ttccatcaag
     1381 ccaaacttcc caaccaagcc ctgctgatcc tgttgagggg ttttcccagt tatcttcaac
     1441 aaaacgaata tcatgttcta aaggattgat gcccaatttt tccaaagaag caaggtaaag
     1501 ttcttgaata tttgatggtg atggtttcat gaccacttga aattggtggt gttggtaaag
     1561 acgatttggg ttttctccgt aacggccatc tgcaggacga cgtgatggct ctacataagc
     1621 cgcattccat ggctcaggac ctatagcacg taagaacgtg taaggactca tggtcccagc
     1681 tcctttttca ttgtcatagg cttgcatgag catacaaccc tgatcattcc aatattgttg
     1741 taaggtcaag atgatttctt gaaaggtaag ttttttagac atttcgtact cctttgatag
     1801 tagtaaaatg gtatattatt gacaatcgtt tttttgtcat cagtaaaata cctgacgatg
     1861 ttactagcat gtattacagg tctaggcacc aaaaaaccgc attttgatgc tcctaaatca
     1921 taagacctag gggcgtcaaa acgcggttcc accctaattt attacttcat ttatatagta
     1981 tctttttggg caatattgac aaatatactt aatcacactg cccaaacgga agcgccaatc
     2041 tgcagtccta ccattcggct ctaactaccc cgaactcgct ttagataaga tacttgcatc
     2101 ctttttccta gagtctagtt tagcataaag ccattagttt gtccatcatg agcttaaggt
     2161 tttgttcgag taccgtttgg aataatcact tccgctaata gcttgttttc ttctcgaata
     2221 cgtaaatata ttactacaat gtagcatggg aaaagaagca tagccgtaat tttagcatgg
     2281 caaagtaagg ctatgcccac cagctcaggg gcgatattta aaaagtagtt aggatgttta
     2341 atcgttttga acaaccagtg atccacatat ttgtggtctt ttgctaacat caattttaca
     2401 gtccaaatgt cacctaagat acgtgtcact tcatataaaa cagctactga taataacatc
     2461 aacaaaagac ctaaaaaact gatgccatca aacttaattt gtttaagcag cgcttcaatc
     2521 accgcaaaca cataaatcat aatgtgaagt aacgtcaaaa atttcgtgtt ctgagcacca
     2581 aattcctgtc ctccttgggc taatatggct ttttcatttg ttatcgattt cttcaaaaat
     2641 actaaacgaa tagtaaacat agctaacatc actaaaaaga tggtcacaat acggctcctt
     2701 attttcaata ataatagttt ctttcacaaa acactaataa agattatagc taaatgataa
     2761 acctttgtca aaccgttttc aaaaaagatt tagcgaatta tggctaaatc tttgtagttt
     2821 cttaaaaact tgtagtatca gggttaggaa tcgctgacat tcctgagaga tagcgaattg
     2881 tttttttatc ttctggtgtc aagctcacat caaaaatagc catattttcc ttgatgcgct
     2941 catcatgcac cgattttggc aagggaataa aaccttctgc cagcgaccaa gctaaggcaa
     3001 cttgtgccac tgttttgtca tatttattag ctaactgctg catagtctca ttatcaaaaa
     3061 tctccccttg tcctagagga ctccaagctt ccaataaaat ctcatttgcc ttacaataat
     3121 caaccacttc cttttgatag caacctgggg ctaatcgaat ctgattaatt gctggagtta
     3181 ttttagctgt ctcttgaaga gcttctagat gatgcaccat aaaattgctg acgccaatgc
     3241 ttttaatgag ccctgcttca accgcctctt ccatatattg ccatgcttga gcatttgcct
     3301 ctttccaagt gttacgcaga gcttttgggt ttggccaatg gataagatag agatccacat
     3361 aatccagacc aagacggtca agagaagcag ctaaagcgtc ttttgcccct tcataactat
     3421 gggcgtcatt ccagagttta gttgtaataa ataagtcttc tcgtagaacc ccagaatcct
     3481 tgatggcacg acccacactt tcttcatttt tataaatagc tgcagtatca atatgacgat
     3541 aatcagcctt gatggctgct aaggtagatt ggtaagcttc ctcaccatcg gctgcttggt
     3601 aagttccaaa tcctaaaacg ggaatctcat agccacttgt catttttact gttgttacca
     3661 tcacaaaaac cttcttttat caatctctgt aagcgattac tgtaatctat tctatcataa
     3721 agaaagaaaa tacaaaaaga attggcctgc cagacatagc taccccaatc cttttgtatc
     3781 tcttaggcat caaaagcttt ttgcccattt aaataggttg caacaagtgt taaatcctta
     3841 tcaagaacaa taaagtcagc cgcatgccca gctttgattt gaccacatac gtcgtcaata
     3901 ccgacagaaa cagctggcac ataggttgcc atatgaatgg cttctgccgg agttgcgatt
     3961 ccccaggcca ctacatttct aaggccgtct tttaatttca aaatagatcc tgccaagttt
     4021 ccactctctt taagacgagc agtgccattt gccacaacca cagagaattc ccccaagagg
     4081 taatcaccat ctggtgaacc acctgctcgc atacagtccg taatcatagc tacatgatca
     4141 tgcccttttt gcttcatcaa aatatcacaa gcaattggtg agacatggtg gccatcacaa
     4201 atcaactctg cgtaagtatt tggaagatta taaaccgctc ccaccattcc tggttcacgg
     4261 tgggtcaatc ctcgcatgcc attataagca tgaacccaaa cactagcacc agcttgaaca
     4321 gcttctttag cctcttgata agtaccgttt gaatgcccta aggccactgt tacgccttgt
     4381 tttgtcactg cggacacaaa ttctttgaca ccatcacgct caggagcaag ggcaattttt
     4441 ttgatgagcc ctttagcggc tttttgccaa gcatcaaatt cctccaagcg tgggtttttc
     4501 atataacttg ggttttgagc acccttatat tcttcggtaa aataaggacc ttcaaagtaa
     4561 ataccttgta ttttagcacc ttttacctga tcagcaactg aagcaatagt ccctgatact
     4621 ttttctaact gctcaaaggt agaagttaag gtcgtcggta aaaaagacgt tactcctgtt
     4681 gctaatagtc cttcactcat ttgatgaatc ccttgggcag aattatccat gacatcagct
     4741 cccgcatagc catggatatg cgtatccaca agacctggtg caatttgata accggtgtag
     4801 tcaatgattt gcgcatctgc cggaacaatt tctgtccact ccccaaaaac accatcatga
     4861 agacttaggt agccagccgg tttcacctct gttgggtaat aaaaacaatc tgctttaaga
     4921 tagcatgtca tcttttttcc tccctttttt ccttattata cgccttattc tttactttgt
     4981 aaatggtata taccactttt tggattcaaa aaagaaaacg tggatgatca ttcacgtttt
     5041 ctcttttttt aaagctggtg tgaaagtact ttctctgcta aattcaaggc atgatctgtg
     5101 atgcgggtat agtgggaaat aatatcaata aaattaatac ctgcttgtgc cgtacattct
     5161 ccacaattca agcgcttaat gtgggtttta cgtaatcgtc gctctttttc ttcaatttct
     5221 ttatggcgag tcacaatagt ttgcgccaag tctgtatcac tatcaacgat agctctaatg
     5281 gcatccagtg ttaaacaatg cgtcaattga tacatctctg tcaattcttg acgagcagat
     5341 attgaaaaac caatttgttt agatatgatg ccttcaatta gaatgcctaa agactcagaa
     5401 tgatctccaa ttctttccaa atcacgtgaa gagtcaagaa taccagccaa gacttcattt
     5461 tcacttgggc tgagggcttc gttagaaata tcaaccaaat aagtggttaa ctcctcatcg
     5521 atggtatcaa ctgctctttc ataacgcttg accttttccc caaatttatc gtcagctgtc
     5581 ataatataac tgtaagaagc ttcaaaagct tgaatcgcat aagaggctaa atgaaccaat
     5641 tccttgtggg catttcctag tgcgatagaa ggggcttggg taataagtaa gcgatctaaa
     5701 taaagggctt cgtatttgac cacttcatct tctcctggaa tgagtctagt cacaatcata
     5761 gctagtagac taatgaaagg aattaataag atggtattag tgatattaaa agaaccgtga
     5821 gaaaaagcga tagtcatctc aggcgttaaa ctcaactttg attgtagcca taacatcaat
     5881 gatgtgaatg ggactaggat aatcataaaa ataattgtac cgatcaaatt aaataacaca
     5941 tgagctgctg ccacacgttt agcagcaata tttgaaccta tagctgctaa gacagctgta
     6001 atgcaggttc ctatatttga gcctaacaaa ataggaatag ccccctgtaa ggtcaaaaga
     6061 ccgcctgaaa acagaccctg taaaatcccg ataatggctg ccgatgactg aatcaacatg
     6121 gtcaaagccg ttccgataaa gacaccttgg aagggtttat cacctaatgt cgctaaataa
     6181 ttttgaaagg ctgacacaga tttcaaagga tccatggcat ctcccattag gttcagcgag
     6241 aagaaaattc ctccgacacc aaaaatgata cgcccaaaat tgttgagctt tttattagag
     6301 gtaaagaaaa gacaggctgc accaataaaa atcatgggca aggcgtaatc tcctagttta
     6361 aaaccaatta aaaacgaagt gatagtcgtt ccaatattag cccccataac aattccaatg
     6421 gcttgtcgca aatttagcaa acccgcagaa accaaaccaa ccgtaatcac agtgacgcct
     6481 gaactggact gaattaaggc agacatggca attccgacta agataccaaa aaagggatta
     6541 ctggtgtatt tatcaatgta ataccttagt ttatctcctg ctgcttgttg cagaccatct
     6601 cccatatact tgatactgaa aagaaagaga cctaagcctc caaagaaatg aaatgcaatg
     6661 tcttgccaat ttactgacac aatattgtcc tcgctcaatt ttttagtcta ttctatttta
     6721 atgtattacg gtctttatca caaggttttt ttaagcgttt ctgtgtatac cgatgtcaac
     6781 atttgcatat tattggtttg ataaggtgtt aggcttttcc gatattttac atcatttgtt
     6841 tttgcacaaa tcttttcatt tcgtttaatt agaggtataa tatggctacg atgaaacaat
     6901 atcataaagg agattccatg actaaatcac aaaaagaggc gctttattgg atgttgagtg
     6961 ttctaactat cactctaata ggtggctcct gccttatttt tggatcccac cctcaaacgc
     7021 aagataaggt agctaaacat tctaaaagtg ctgctagttt actaaaaaaa gcagttaaag
     7081 cagttaatga cgctgatcgt ttagccactg cagctgctat ccaagaagcc cagaaagctg
     7141 ttgataaatt agcagaatct tctaagaaaa aaacgctaca agaacagcta aacgttgcca
     7201 aagcaaagca agagcaagaa gatgcagcta ctcaagcagt taaagctgct gaggagactc
     7261 tcaatcaaaa tcttaaagat atcgcccaaa aagcagttaa cgacttaagt aacaaaggta
     7321 aaaaagccgc tttacaatct cggttagacg ctattttacc agcgaaaccc attattgatg
     7381 aatttccaag acaaagtgga gaaataacag ataactctta ctggacacct ttcccaggag
     7441 acgtctcaga tacttatgat aattcccagt cacctacttt agacccaagc tcagaatctt
     7501 cagcttcaga tgttacgcca caacctagtc atcctgatcc aattccgcct cagacctctt
     7561 cagaaccttc cgactcagga gacaagcaat catcaaaaga gtaatacaaa agtttttcgt
     7621 aaaatcaatc aataaacgtt ttagacggct atcttagtga ttagtcttcc tgacatctta
     7681 aaaaagctag ctcaaatcaa aagagtctag ctttttgttt tgttagatag cattaaattt
     7741 cgtagcccat taaaagtcct ccgtcttcag cataaaagct acacaaacct gaggtccttc
     7801 cagtttgaat cacagcatca ggatataaag atttgatttt ttcactgatc tgctcacaaa
     7861 tttttggatt ttgagcatga gcaatgtaaa cttttccgcc tacataaccc tctttttgaa
     7921 tttcttctat caaagcagaa actgcttttt tttgaccacg cgctttttga agaagttcaa
     7981 gcgttccttt attgctagct ttcccaacca ttctaatatt gagtaagcca attactttac
     8041 ctactaattt actcagtcga ccatttttaa ccaaattatc aaccttggca agcacaaaaa
     8101 tcaaacgtgt tttttgctga taagctgtga tctgtttgac aacttcttca aaggataatc
     8161 caagattgat caaccgctca agctccagta cgagcaaatc catctcgcca cctgctgata
     8221 aagaatcgat taggtgaata ttgacattag gattttcttc aagaagttca tttttagcca
     8281 gtcgtgcact attatgactg ccagataagg tccctgtaat tgtcatcacg ataacattat
     8341 ctgcacctct ataggcctgt aaaaaggctt ctgggcttgg acagctagat gtcgttgctt
     8401 tagacgactg gtacatagtt gtcatcatat tatcgatatc taatccatca tcatctctaa
     8461 aaatttctgt gccaatctgt agggtcaaag gcacacgttc aaagcgcaac tctttggatt
     8521 gtctagtcaa acttctaaga tcacatcctg aatctgttac aattttccaa gtcatttttt
     8581 atccttcttt ttctctaatt tgtgttcagt aacaaagacc agattattaa gccttcgcta
     8641 agatgtctag gctaatggta ataactagtc attaaatcct atgttttatt actagccttt
     8701 tcaatagtta gtaaagtcat ccaatagagc tatacaagga ggtaatgagg ctcctgataa
     8761 ctaactttag ttgacaaact aagacttttc ccataaaatt atatcattat taagtcggtt
     8821 tttgctactg ataactcatc agatgtaaca cttgaaaggt atttgtgatg actgataaag
     8881 cactctcaaa aagatcactt caaaacttaa cacaatttaa taaagaaaca cgacgcatag
     8941 cacgtgaatc tatggaaatc gccttactga atcttctaga aacaaaacct ttaggtgata
     9001 ttacgatttc agaattggtg acgaaagcag gagtatctcg taacgctttt tatcgtaatt
     9061 atacctctaa agaagccatt atagaacaac tgttagtagg ggttatccgt cgtatttttc
     9121 gtggactaaa acaatttgat attaaaactc aggcttatca agcctggctc tatcttttta
     9181 ctgaagctaa aaaagaagct cagcttctta aaatgatttt caaacatcac ctgcaccatc
     9241 ttctaacacg attagtcact aaacgtctga aagcttatca aaaattaaaa gacaaaaaac
     9301 aatcgcacta taagcgcctt ttttggagca atgctattgt ttctgtcttg acaaactgga
     9361 tttcagatga catgatcgtt cctgccgaag aaatggctgc tatgggcttg cctctattaa
     9421 cgtaaaaagg ttcccaaaag gaaccttttt acgttaatag ttagtctttt tgagctgcaa
     9481 gtgcaaactg acggatagcc tgggccacac ccgccatatc attagtcaaa gtgactttgt
     9541 cagctaatgg cttgatagct gctgaagcat tttccatagc aactcctaaa ccagcataag
     9601 ttaacatctc aatgtcattg ggagcatccc caatagccat cacttggtca gcagttaaac
     9661 ccaaatcttc tactaattct ttgagagccg atgccttgct gactccctga gggagaattt
     9721 ctaaaatatt atcttggcta cgaacaacat ggaaactctg actaagctga tttctcaccg
     9781 cacgttcaaa ggcatctagc gcagcttttt ctcctaagta catggcttga aaaatcaggc
     9841 gaggagtgtc cgacagctct gctaaggaga caggcttgac aatggtaaat accaaatctc
     9901 catcttcctg cacaaggtct ggcacttctt cttcaagcac caaataatcg ttttcctcag
     9961 ttaaagtcag gtaaatatct ggaaaacttt ggcttagctc ttccagcaat tcaatatctg
    10021 aaaccttcaa catttttgaa tggcgtaatt gccagtcagg actactataa gtactacagc
    10081 cattattgat aatgaggaat tcctcttgtg tcaaacctaa ttggtcaaaa tagggtcttg
    10141 tccctgactg aggccggcct gtacataaga caatttttaa gcctgactga gctgcttctt
    10201 ggatggctgt gatattctct tttggaatct gtttgtcctg gtttaataag gtgccgtcca
    10261 aatcaattgc aattagttga atcatcctat ctttcctctt tccatttgat tttagggagg
    10321 ttccattttt tacggttgcc aatcatgcgt aaagtcgtga gtaaaacaac caaggcataa
    10381 cattcaatcg ttgaatctgc tagtttaaaa tgcaaaacaa tagctgcaag aatagaccac
    10441 ccagcataga tttcactacg caaaacacta ggttttcgcc ctgccagaat atctctgaca
    10501 acaccaccgc ctgcaccagt caacacagct gctacaatga cagcacttaa aggctggtta
    10561 agacggacag catgcaaggc tccttggaca ctaaaagctg ccagacctat ggcatcagtc
    10621 aaaacagctg cccgtaccca acctctagct attagcttag gaaaaagcat aatcaaaacc
    10681 atagcaaaga aagcgcaagt gaattctggc ttttgccccc ataaggcctc tataggtaaa
    10741 ccaattaggg tgtttcgaat ggctccgcct ccaaaggctg tcacgaaacc taaaataaaa
    10801 atccctaaaa tatcaaattc ttcttccatg gcaacaatag caccagaaag agcaaaggca
    10861 atggtcccga tgatatttaa aatttcccac atatcaattg tcataagcta ccctattgtc
    10921 ttttagtctt cttttagttt accacgtttt cctttaaaaa ataagtagaa aaagataaaa
    10981 tgtaaggata aaaaagcaag gataaaaccc attttcatcc ttgctacaaa agattcaaac
    11041 aattatcccc atacttatct tatcacatca atgagagctg cttgatagga taaggttgtt
    11101 ttagattttt tccgtccaag ggctagcggt ctcttcgagt accctgttta actcgtcaat
    11161 attttggaag ccttcagtgc atagccactt tcttgcttcg tcctctcctt tagtaatata
    11221 aactggaacg gatcctgccc acgtggcacg cccacacaaa acaccgctaa attgagcacc
    11281 tgctgctgct gcaaagtata atgtctcttg aaaaagtttg gcagatacgc ctgcactcaa
    11341 atagatataa gggaggtggc tggcagcttc ttggtcttga aaagctttaa tagcctcagc
    11401 ttgactgtaa tggacttccc cttcagtaaa accttctaca taagccatat taacaggaac
    11461 ctctactttt agcacatcaa cgccaaaacg cttatccgaa aatactgaca tagcaccgtt
    11521 aaccttatgt ggcttaagct ttgcgtatgc cgcactgttg ttatctgata ttctctcatc
    11581 ataactcaaa agttcaagaa aaaaagggat gtcttcagct gtacattctg aaccaatgcg
    11641 ttcaatataa gcttgttttt gtaaattgat ttgttcatct ccatcaacat cataatagag
    11701 caaaaattta atagcatctg cacctgctgc tttcaaccgt ttgaccgacc attccactaa
    11761 gcaatcgggt aaacggctag tggttgtagc atcataacct gttttttcgt aagctaacag
    11821 taagcctgtc tgattagctt ttaccttagt agccagcaac ccatattctg gatctaataa
    11881 aatagatgaa gcataaggcg tcaattcctc agaaacgaga actttcaatg tttctatctg
    11941 tgtaactgtc gcttctcctt cttgatgtgc tgccatcatt tgcttcagtg cacctcgttg
    12001 atcaaaagct aaagctgata tgattccttg atggctcact ttttctaagt aatgtctttt
    12061 atttgctgtg attgtcatgt gatacctctc ttacttgaag ttgctgatat aattgtttaa
    12121 aagttgccat agtcatcaaa tcttgataat agtgagtagc tagtctctta ggcagactgc
    12181 ctgagaagtt aagacatcaa acggcttagc aatagtactc atgtggctca aagagacttc
    12241 ggcttcgtcc acatcactgt agggaccagc ttccaaaatt tttgtctgca tgccttcatt
    12301 taaaacagca atacaatttc tcgtttcccc tttgattttg aaaaattggt tagaaatgcc
    12361 ctgttcttgt aactgatgaa tgataaagtc acccagttta ccaccactaa atcctgttgc
    12421 cataactgac cagcttttgg tcacatttag ctccttatca ccagctgttt ttgccgttct
    12481 gtcaacacga ttaaccgtgt ccatagccag acaatctaaa ggataggaaa tagcgacaga
    12541 aggatttaag ataactgtta aactcatctc ttcttcctaa tcgtgatact caccacggtc
    12601 ccatttttct aaaaattctg taaagaaatc aggatcttct tggttggcat gatgactttc
    12661 caagtgggct attttagcaa ttagcttctt attctcttca gtttctttgt attctgcctt
    12721 gataaaagca tctataatat cacacataag aagttcacca gtgattttac caccaaagcc
    12781 aatcacattg gcattcaatt cttccttggc ataaagcgct gttgtcatat ctcgaacaag
    12841 ggcggagcga atacctggta ccttgttcac ggcattatta atgccaactc cagttccaca
    12901 aatacaaaca cccaagtctg cttgtccatt aaccacagct tcgccgactt tttttccaaa
    12961 aatagggtaa tgggttcttg tatggtcata agtgccacag tcaataacgt catagccttt
    13021 agatttcaaa aaatcagaaa cagccatttt ttcgttggtg acaatatggt cacaaccaat
    13081 cgcaattttc atcactttat cctcctttag gccattttat tgagcatgtc aacacgaatt
    13141 tgatgacgac caccatcgta gggaccagtc acaaaacctt tgacgatatt cttcgctaat
    13201 tctggaccta caatctctgc ccctattgtg atcatgcggg cattgttgtg accgcgcgtc
    13261 atgtaagcag agcgttcatc tgacacttca gcagcaacca ttccttttaa ttttgtggct
    13321 accataaagg gacctgctcc gtaagcatcc accataatgc ctaaacgacc ttctgcttca
    13381 ttaatggctt tcgccaccgc taatgtgtta tcaataaaat cactgttaat atcagtcacg
    13441 tcaataatgt catagccttc ttcttgaaga aaacttttga tcaattcttt taatgcattt
    13501 ccgtgtgcat ctgcacctaa aataatagcc atagcttttc cttttctaat ccaaaacgct
    13561 tgccaatcta gagaaggggg acatgattac ctgtccttag atcaagatga ttgccagtag
    13621 tcttagtgtc ttccattatt tctttcaaga caaagcactt gtgggttccc acagagcgcc
    13681 ttgccttaca tgaggaatgc tcttttctcc ctaggggata aggcaggaat accttaagcg
    13741 gttgtctgct attcccaata gttttttagt tagtcaccta acctgatttt atgtcattgt
    13801 tttcgcatac tcagcgttac gtgccttcat ttggttagca taccaagcaa agagacctag
    13861 gtaaatggcc acaaagatga ttagcgtgat gattgaggca atctgacctg ttgtcgcttg
    13921 accaatcaca taaccaaaaa ttttttccat tggtccttca agtgttgaat gcgtaatcaa
    13981 ggaaccagcg cttgtacctg ctgggaaagc gcctactttt ttagccaatt cagttgcgaa
    14041 tggggcaatc atggttcctg acaagaggaa taacggcaat aagagggagc caaaaataat
    14101 catgcgaatc aaacgaccac gtgtgaccac aagaagagct ggtgtcatcc ccatagcaat
    14161 aattcccgcc aatggtaaaa tcccattgcc aacttttgat aagagaacgg cttcaatcaa
    14221 catgattggg gcaagaatat tggcacaggc ccagatttca gcgcgaccag caatgaaagg
    14281 ccagtccaaa ccgatattga aacgacgtcc atgcattcta gcattggcaa aattagtaat
    14341 cccttgtgac aaaggctcaa cagctgcgat aaaccaagaa ccaatcaaag agaaaagttc
    14401 caaacaggca cccgcggtaa agcctagacc aaaccaattt ttgatagatt caacagtgaa
    14461 atgaggatct cccataatcc caatcacaaa acctagagcc attccgataa agaacttaga
    14521 gccccagaag ccaatttttt tgttcaattt agcagcatca aagtcatatt tatctagccc
    14581 cggaaagacc ttgtcaaaaa tcttatctaa gaccataatg attggattca tcatgtagtt
    14641 catgtgagtt gaagtcatcg gtgattgaga ccctgtccca agaaggtcat caaaggtcgg
    14701 tttcatcaaa tcagagttaa tgattttcaa taccccaaca agaataactg ccacagtagc
    14761 aatcaaaaga gacacaaaga ctggtaaatg gttgcgagcc gcataccaca taatcaatag
    14821 acccgtaatg gacaaatgcc aaatatcaaa aatatcgacg tcaagggtgt ccgttttttt
    14881 catgacaatc atgacaatat taaccaccag catcaccagc aagaaataaa gggtgtaagg
    14941 ggaaccccag gtaattgttg caagcggtgc ccaaccgaca tcaataatat tcaaactgat
    15001 tcctgtattt ttgacaaagg cctgcaaaga ctctgaaaaa gcccccgtca aaatcccaat
    15061 aatggctcca atacctgtaa gagcgatagc taacttaatc ccgccttcca gtgcctttgt
    15121 gaatttaacc ccgaaaatca tggctaaacc tgtcatgaca atcagcatga ccacacctga
    15181 tcccaactga ataggaaatc ccagaatctt gttaataatg tctaaaaaag gttgcatcat
    15241 cttgtctcct tatgttttta ttaactcact gcaaatggtt ttctttaatc acgcgctcta
    15301 attcagcaaa aacaggctca ctcatgtttg ggatacgata gagaatcggt cctgcttcta
    15361 ctgtgggaat tggcatctca aatcccaagt cagtttttgc aatcggcgta aaaatatcat
    15421 aacgagacac caattcttct gtgatgtctt tgaccatcac cgcatcacag tgaacatcgt
    15481 aaccacgatc actcatctga gtttcaatcg catctttaat ttgatggctt gagttaacac
    15541 ctgcaccgca ggctgctaga attttaatca tgctgaaaca ctcctttttc tattaaatag
    15601 tttgaaatag cttgtttatc atcttttaga ctggctagat agctaagatt gcctttcgta
    15661 ataaagaagg taatgagatt agatagaatc gtcgtttgac cctcgttttg actattgata
    15721 ataaagaaga aatccgttac caaacagtct tcctctggat taatcatgtg cttaaaggta
    15781 agggcttgac tatttctaac atagaccact tgatcaacca agcaatactt ggtttctgta
    15841 tgcggaatag ccgcatacaa aatatctgac ccatctttga ggtccacttt gagtcctgtc
    15901 ggaaataccg cctcacgctc cactaaagcc tgatggtact cttgcgtcac atacccaacc
    15961 ttttccaagt ggctagcaac aagatcaaaa agctctggct gcgtccttgc ttcagtaaat
    16021 agaatattag gaaacactcc ctaccgcctt tctataagta tcaattttta acaattgtca
    16081 tctcatcatc aacaaatagg taaccgttta caaaatcatt atagtataac cttcaacata
    16141 attcaacatt tttacgcaat attttttgtt ctatatgttt gtttttgttt tgtttatttt
    16201 gttttattga aatatgaagg tctatatgct atgataaaca taagtaaata aactatagaa
    16261 aggagcccct tagatgttaa aaagagaaag acttctaaaa attaccgaaa tagtcaatga
    16321 gcaaggtatt gttactgtga atgatattat tcagacttta aacgtttctg atatgacagt
    16381 tcgtagagac ttagatgaac tggaaaaagc cggcaaattg atccgcatcc atggaggtgc
    16441 acaaagtatt accatgccta ataaaaaaga gcggtcaaat attgaaaaac aaaccgttca
    16501 aacaaaggaa aaatgggaac tagcttcata tgcgacacaa ctagtcaatg atggtgaaac
    16561 aatctttatt ggtccaggaa caactttaga atgtttcgct gagcaattaa aaaatcgtca
    16621 gattcgcatt gtgaccaata gcctccctgt ctttaacatc cttcaggaca gcgaaaccat
    16681 tgacctgatt cttatcggtg gtgaataccg atctattaca ggagcttttg tagggtccct
    16741 tgctagtcaa aatatctcat ccttaaaatt tgccaaggct tttattagct gtaatggcat
    16801 ttataaaaac gatattgcaa cttatagcga aactgaagga gagattcaaa agctagcttt
    16861 taataattct attgaaaaat acctcttggt agataaccaa aaattcaatg cctacgactt
    16921 cttcattttt taccatttaa acaacattga tgctgttgtt acagattcgc aaataactga
    16981 ggacgtcatc gaacgttata gtcagttcac acaattatta gtagcccacg aaaacaagga
    17041 gtaaccgttt catcaagaat ggacagcctg tcagcgcatc gtccttaaac accttctggc
    17101 aaaagtgatt tgcccccaga gaggtgtttt tgttttgctc ggaacacacc tgctaacgtc
    17161 agagtcttta tgagtgacca caaaaaaaga agcccagatt aaaaaactgg aacctctttt
    17221 gagatgaagt aaggctacca aaataaccta agaccattta tgtaattcaa atttggtagc
    17281 cttcaaagca cgcttgagta ggaaagttaa aggacgtcct gtcaccttag cctctccttt
    17341 ttccaaattt acctggaccg attgcacacc ggggacagct gataattttt tagtaaccgt
    17401 tcttgcacaa ccgtcacacg tcattcctgt aacctgatag tgtttttcca tttcgttttc
    17461 tccttcaaat ggtttttcct tttaaacgca atgcattcaa aacaactgat actgaactaa
    17521 aactcatggc aaaacctgct aacatcgggt tcaatagtgg acctccaaaa agatgaagta
    17581 agcccatggc cactggaatc atgaggacat tgtaaatgaa tgcccaaaat aaattttcct
    17641 tgacaattct catagtcgct cgactcaatg acatagcttt caccaaatcc agcatatcag
    17701 gtttcatcag aatcacatcc gccgattcaa tggcaatatc tgtccctgac cccatagcta
    17761 tcccaatgtc tgctacagcc aatgccggag catcattaat accatcacct accattgcaa
    17821 cttttctccc ttgagagcgg aggtctgcta tcacgcctgc tttttgatca ggtaagactt
    17881 gactgatcac atctgtaatc cccacttgag aggcaatagc cttagcggta gcatcgtggt
    17941 cacctgttag catgatggtg tgaattccca gttgatgcaa agcttcgacg gtagcttgac
    18001 tatcttcttt gacagcgtca gcaatactga aaagagctcg tagctgcccc tctttagcat
    18061 aatatacaag ggtttggcct tttcctgaag ccttagcaca aactgactga acacaagata
    18121 aatcgatacc aagaattccc attaaagcag catttccaat cgccaaacga cgcccttcaa
    18181 gctgaccagt gactcctagg ccggttaaag actcaaactc ttccactggt agactatcgt
    18241 aaccagcttc ctgagcagca cgaacaatag cctcccctaa ggggtgttga gaataggcct
    18301 ccaaggaagc agcttcttgc aagataaggt gatcatctcc cgaaaaaatt aggagctttt
    18361 gaagacttgg tttcccctcc gtaaccgtcc ccgttttatc aaaaacaacc gtatctacct
    18421 gatgagcttg ttctaagatg tcaccacctt taaaaagaat accattttca gctgcacgcc
    18481 ctgttccaac cataatcgct gtcggagttg ctaaaccaag cgcacaagga caagcaatga
    18541 ctagaacagc gatggctgtt gtcaaactaa aacgaaaact ttcctgcatg aataccaacc
    18601 aaaatacccc tgttaacaga gctaatacca aaaccaccgg aacaaagaca cctgagactc
    18661 tatcagcaat agctgcaata ggtgctttat tttcttgagc attctcaact agttggataa
    18721 tttgtgctaa caaggtatca ttcccaagct tatctggttt aatcgtgagg gcgcctggcc
    18781 cattcaagct gcccgcaaag acattatctt tttctccctt ttcaacaggc aaactttccc
    18841 cagttaaaaa ggattcatcc aaactgctat gtccttccac gataataccg tcaatagaaa
    18901 ctttttcacc tggttgaacc aggacaaggt catcatagct aacttcttct aatggtaaca
    18961 attgccattg gctgtttctc cataccctca catcagtagc cttcaaggat aggagctttt
    19021 gaatagcttg agaagtacgg cccttagaac gactttcaaa atactttcct agaccgatga
    19081 gtgtcaaaat cactaccacc gattcaaaat aaagggagtg cacaaagtgc gcctggccca
    19141 aactgatttc aaccactcca taaagactat aagcaaaagc aaagctggtt gctaaagcta
    19201 ccaaggagtc catattagga tgtcccttaa acaaagcttt aaacccatta tggtaataat
    19261 gacgatttaa tactaagact ggaatcgtca agagtagctg actaaagctg taaacgaaag
    19321 gatagcgatc tggttgcaga aatggaggaa gccataagcc caccatgtga cccatagcta
    19381 ggtataatat aggaatggtg aatagggcag accacaagac ctgagaccaa ataaccttta
    19441 agtcttcgtc acgacgacct gtttgcatat gttttgcatg ttcatcaaag acttgtgcac
    19501 cataaccagc agcttttacc gcttgaataa ctttggccgt ttctaaatcg tcatcttgat
    19561 aagtaaccgt gagcttctca gtcgctaaat tcacaacagc ctgttctacc tcaggcaatt
    19621 gattgaccgt tttttcaatt gttagagcac aagaggcaca actcattccc tccactaaaa
    19681 atatctcttt agccattaat acgtctcctt tttctgacag tggcactgcc caggcaggca
    19741 attacacggt acctcaagaa ctgcattttc ttttttgagt tctagtagct cttggaatgc
    19801 ctcgatttcc tctaaggtca tcggtaagtc ataaagtcgt tcaagaagta gacgcgcgtg
    19861 ttgccgctga caaataccgt ctaaaacagt cgctagtgct tctttttgta gcaaagtctc
    19921 atccaaaaga gcttgataaa tataggccct accttcccgg taagtttcca aagccttttt
    19981 ttccaccaaa cgcccaatca aggttttaat ggtagaatct gaccattgat attttttcct
    20041 taaaatagta ataatatcgc tacttttaat atcaccactg gcccacacca cacgcatgac
    20101 ttcccattcg gcagctgata tctgttgcat aacgtcacct tcattcacaa tatatttacg
    20161 tttgtaaatt aattataacg aatttaacta catttgtaaa taaataactt ttctcatttt
    20221 tctatcctta tattgacaaa tgaatcgttt ttactataat attattgcaa taaaaataac
    20281 atttacatta aggagatacc cttgaaacat cctattcgaa aaacacttgt caccttaggt
    20341 ctattactga ccttatgcct gccaactcca gttgcagcta gttctcgttc ttggaagagc
    20401 tggtttatcg agcaatattt ctggttaaaa cgtgacaaga gttactattc taaacaagat
    20461 gacccaagct tccaaagata ccttgatgcc tgtcgtgaac aatctgataa accttatcaa
    20521 ctagatacta atttagtcaa tggtcccctt gttcaagaaa atctttatgg catgcaggtt
    20581 tactcttgga atgataatgg aaaacctgat caaaaaacaa ttatttatct tgccggtggt
    20641 tcttatctta acaatccaac gacataccat attaatatgt taaagacatt atccacaagt
    20701 cttgacgcta aaattgtttt acccatttat cctaaagccc cacgttatac ctataactat
    20761 actatgccaa aattggtcaa tctttaccaa cactattatc ataaaaatca gaatattttc
    20821 cttatgggag attcagcagg tggaggttta gccttaggtc tagctcatgc cctacacaat
    20881 gaatcagtcc ctcaaccaaa gcagctcgtt cttttatcac cttggttaga tgttactatg
    20941 tcacacccag agattccaaa atacgaagat gctgatccta ttctatcttc ttggggatta
    21001 aaacgagtgg gagaattgtg ggcctactct gctgataata ccaaccatat ttatgtcagt
    21061 cctaaaaatg gtccgatcac ttatctacca ccaattactt tatttactgg gacacgagag
    21121 atcttttatc ctgatattcg cgattatgcc gcaaaactga aagccgctaa ccacaatatt
    21181 accttcatta cccaagaagg catgaaccac gtttacccaa tttatcctat cgaagaggca
    21241 aaaacagctc aataccaaat cattgatgcc atcaacaaaa ctcctcaatg aggggaataa
    21301 ttcctacctg ccaccagtta atctggtggt tttttgtagt ttgcaccaca aaataacaat
    21361 taaaaagagc tctatcataa tgataaggct ctttctatca taacatccgc accgcaatac
    21421 ttaggatttg ttgtcaagtt ctcgtaagag ttgatcaatt ttattaccat aggcgatgga
    21481 attgtctttt tcaaacacca aatctggaat tttgtacatg gtcaattgtt tgccaagttc
    21541 acgtttaatc gttccagtcg ctttttcaag ccctgtttgt gctttttgat tatcagatgc
    21601 caagtcactc ataatagtgt aataaacttt agcaagtgac aagtcaccct gcatttgcac
    21661 ttctgtaatc gttactccct gaacgcgtgg atcacgcact tttttctgaa gaatatcatt
    21721 tacttcgcgc ttgatttcca tcccaacgcg gtcaatacga tgattagcca tagccatttc
    21781 ctttccacat ttttaaaaca aaagctaggc tgaaagccca gcttatgaca ttgctacctg
    21841 ttttgataac gacaattaaa gggaatctga gaattccatg acgagactgg aaggaatgcc
    21901 ccaactagct catctggtag aaaaagtcat tattttcgac agaggaaaaa cgtcacatct
    21961 cagaccttct tagcccctat tttctcacaa tttcttccat aatataggct tcaatagtat
    22021 catcaacttt aagatcgtta aagttttcaa tcatcaaccc accttcttga gcattaccga
    22081 cttctttaac gtcatctttg taatgtttca agctggccag tttaccatca aaaataacga
    22141 cactatcacg gataacacga acactcgaat cacgtgtcac cttaccgttg attaccataa
    22201 agccaccaat tgttcccact ttagaaactt tgaaggtttc acgaataatg gcttcaccaa
    22261 gaattttttc ttggtaaaca gggtcaagtt tccctttcat ggcttcttct acttcttcaa
    22321 tgactttata gataatgcta tgaagacgaa tttccacatc atccgtatct gcttgttgac
    22381 gagcttgtgg ggtagggcga acgttgaaac cgataataac agcatttgat gcttcagcaa
    22441 gggtcacatc agactcattg atagcaccta cagcagagtg aacgacattg acacggacac
    22501 cttccacttc aatctttaca agagatgctg caagggcttc aacagaacct tgaacgtctg
    22561 ctttgatgat gacattaaca gtcttgattt ctcctgcttt aagggtatca aagagattat
    22621 caaggctaac acgctgtgta ttttgacgtt gtttgaggag ggcacgtttt gatcgctcct
    22681 caccagctgc acgcgcagct ttttcatcag cgtaaacagc aaagtgatca ccagccattg
    22741 gtgtttcgtt caaaccagta atggaaactg gtgttgatgg ctccgcagat ttaacacgac
    22801 gcccaaggtc atttaccatg gcacggacac gaccaaaggt attaccaaca acgattgggt
    22861 cttgaacatg aagagttcct tgttggacaa gaagcgtagc aatagcacct ttacctttat
    22921 ctaagcgtgc ttcaatcaca gtaccaatag cacgaaccgt cggatcagct ttcaattctt
    22981 ccacttcagc aaccaaaagg actgtttcta atagttcatc aatattttta ttaaatttag
    23041 cagatatctc tacaaattcg cactctccgc cccaagcagt tgagatgata ccatattctg
    23101 ccaattctgc gataacacgt tctggattag cacctggttt atcaattttg ttgatagcaa
    23161 caataattgg aacaccagca gcttttgagt gattgatcgc ttcaatcgtt tgtggcataa
    23221 caccatcatc agctgcaaca atcaaaatgg tgatatcggt aacggaagct ccacgtgcgc
    23281 gcatacttgt aaatgccgcg tgtccgggag tgtccaagaa ggtaattttc ttgccagctt
    23341 cttcaatctg gtaagcacca atatgctgag taattcctcc agcttctcct gttgccacac
    23401 gtgagttacg caaagtatca agcaaagttg tcttaccgtg gtctacgtgt cccatgatag
    23461 ttacaacagg tgcgcgttct acaatatttt caggattgag gtaattttca tcctcaaaga
    23521 agcgctcgat atcagcatca tctacttcta ccttagcctt agcctcaata ccataatcta
    23581 ccatcaataa ttcgatagta tccccatcta aagactggtt ttgagttgcc ataacaccca
    23641 tcataaacag ctttttaaca atttcagcgg gttcgcgttt gatacgtttt gcgatttcgg
    23701 caactgtcat gccttcagta tattcaaatt cttttggcaa ttcatggaat ttacgctcgg
    23761 ttactggttt tggagcggtg ttggtattct taacattttt gccttttttg gtctttttat
    23821 ttttattcca gttactattt ttttgatttc tcacttggtt ttgactattc caactcttct
    23881 tatttttctt ttgtccttct tgtgaatgat gagttaactc acgattcttt tcaggacgtg
    23941 cttgtttttt acggcgatta tcagcagtag atttagcact aatatttgat gactttaatt
    24001 tagtttctgc ttcttcaata gatttcagtg ctgtttcacg atggctcatc tcctcagctt
    24061 gtgcttttag agccgcttct ttagcttctt gtcttgccaa ctcagctaaa cgcttagctt
    24121 cttgctgtgc acgaaaacgt gtttcacttt ggcgtgagta ttcagcattt tgttcagctt
    24181 ttaaggcagc agcacgagct ttgaaatcaa ttttaggact tttcgattga ggctcttgtc
    24241 gtccttgctt tttttggttt gtgaatcgac cattcttgtg attctcctta gcaaaggaac
    24301 ggttacgatc accaactagc tgatgattat catgtctagg tgatacattc gatgcttttc
    24361 gctcaatacg cttatcgttt gtatcacctt gagaacgatg ggtaatcctc ttatctcctt
    24421 gttcgttagt ttgatgatta ttgggctggc gataacctcc tcgacgttct tgagaacgat
    24481 gagaagagcc atttgcttgt tttcgagcag cctgttcctt tgcacgagcc tctctttcag
    24541 ctttaaaatt acgactcttt ggcttagaga cctgtgtttt ctctacatgc tcagaacctg
    24601 tttctttgac cactgttaca gagggttgag caacttcttt gggtttgact gtttgagaag
    24661 ctgtcacatc aggtttagaa gcctttgaaa aacttgaaat aatctttttc gcatccgctt
    24721 cttcaacact tgatgcatgg cttttcacat ctaatcctaa gtatttagcg tgttcaacca
    24781 cctctttact acttttacca atttccttgg caatttcatg taatcttttt tttgacaatt
    24841 tgtgtcctcc tattcatcta ttccataaga gtcctcattt tctttgaaaa tccagcatct
    24901 gcaatggcag caaccttcct tggtttacct agtgcagcac ttaattccag tgcattcaac
    24961 actgtggaga cttctacatt ataataatta cttttatctg tcactttttt tgtcacatta
    25021 ggaccagcat cattggctaa aaatactaat attacctgct ggtgttgaat agcttttact
    25081 actagttctt cacctgaaat cacttttcca gcccgttgag ctagaccaat aagactagat
    25141 aatctttcta aattagtcaa gacctaactc tcttcttttg attttgtgat caacataagc
    25201 aatcaagtca tcgtaaaaac tttctggaat gtccattgag aaactcctgt tgaaaacttg
    25261 ttttttcttg gccattaagg cctcttgatt gtctaatttg atataagcac cacgaccatt
    25321 ttgtttacca gttggatcaa tgaaaacttg accatcctta gtttttacaa tcctaagaag
    25381 atctcgttta gcaataattt caccagaaac aagtgatttt cgtaaaggta tttttttgac
    25441 tttagacatc aaacacctct tttcttacac ttcctcggca gtcataacat cgtcaacaac
    25501 tggctcttcc acaactgttg ctgcttcttt ttccgcctca agacgatcat attcgctagc
    25561 tgatttgata tcaatacggt agccagtcaa atgtgccgct aaacgaacgt tttggccgcg
    25621 acgcccgata gctaatgata atttgctatc aggaactact accgtagcac gtttaagatc
    25681 ttcatcgtca aaaagtacca tgtctacttc agccggagca atggcattgt agatgaactc
    25741 agctggatca tctacccatt gaatcacgtc aatattttct tcaactggaa tttcaagccc
    25801 cgtcttagca tctacacgtt ttggatggaa cttgctgatg acctttttaa tattacttcc
    25861 accacgtcca acaattgttc cgatggcatc aacgttagga ttatgactgc gcacagcaac
    25921 cttggtacgg tcacctgctt cacgagagac actcatgatt tcaacagtac catcaaagac
    25981 ttcaggaatt tcttgctcca taatacgttt gatgaattct ggatggctac gactaacaaa
    26041 gacgttaact cctttaggat tattttcaac tttgtagaca taaacgtcaa tacggtcatg
    26101 tgatttgaaa gtttcacctg gaatctggtc ttggtgagac aattgtgctt ctaaggaacc
    26161 aagattgaca taaataaaac gttgatcaaa ccgttcaact gttcctgtca taatttcacc
    26221 ttcatgctct ttgtattcat tgaacatcac ttcacgcatt tggcggcgca tcttttccat
    26281 aatagtctgc ttagctgatt gagctgcgac acgtccaaat tcattgacag attcttcaaa
    26341 gcgaatctta tcacccaatt cataggcaga actgatagca agagcatctt tcaaactaat
    26401 ctcaagccgg ctgtcaaaaa cttcttcaac aacctcacga accgtgaata cttgaaaatc
    26461 agctgttttt tcattaaatt caataacaca tgattctgat tgaccatagc gacgtttata
    26521 ggcagacttt aatgattctg tcactgcgtc aataatatct gctttatcaa tgtgtttttc
    26581 ttcttccaaa atacggaagg cttctagcat ttctttgctc ataatgttat ctaccttgct
    26641 tgtaaagctt ggcaaaaatc ctttcttaaa ttaatacgat caatagcccc ctaaaggctc
    26701 ccttaattcc ttttgtttag cttgtataaa ctctataggt gttgtttcaa atttgcttaa
    26761 gcgttcctaa aaaagtttag tgcttcgaaa taaaagttat aatttgacag ccattctcac
    26821 cttagcaact gcttgatatg gtatattcac gatcttatga cgtgttttat caagataatc
    26881 aatggtcaac gtttcaccat caaaggctaa taagtctcct tgaaaaactt tcaccttatc
    26941 aatagcttga taaagactca cattgatata agagccaact gctgctttta aactgtcagc
    27001 tgtcttaagc ggacgctcca aacctggact agagacttct agcatatatt ggtttggaaa
    27061 aggatctgga tcaatcgtat ctaacagcgg actaataata ttcgtcaagt cagatgtatc
    27121 ttccactgtg attccacctt ccttatcgac taaaatacta aggatgtagt cactacccat
    27181 tttgtcatac tcaacgtcta ctaattcata aggtgcctta atctcaggcg tcactgtctt
    27241 ggttacgata tcgataatag atgtatttgc tattttgatt acctcctcta tttttatgct
    27301 cttctctaag ataattggtc cttgggaatc cacttaatac aaaagtggcg agacatatcc
    27361 caccaccttt ctgtattatt taagcctatt atattatacc ataatttaag aggaatgcaa
    27421 ggatatgcac tttgttttac tcacaaggag aggaggggat tcgaaccccc gagccccgtt
    27481 aaggactaca cgctttccaa gcgtgcgcac taagccacta tgcgacctct ccattactaa
    27541 agaagttaat actgtatcaa ctcctttatg ttatcatatt ttgaaacaaa atactactag
    27601 aaatttgcct caactcggta aatgacttga cctttattag agaacttctc ttcatattct
    27661 gtcatgacat ttccttcata gttactagcg tgtaagtcaa gccagatctg tctcaaggtc
    27721 atgccgtatt gagaaaaact agctaaactg tactcaaaca agccccgatt atcggtttta
    27781 aaatgaattt caccgtgttc tggcaagata cgcttgtaag tgtctaagaa atccttgtag
    27841 gtcaaacgac gtttttcatg cttggttttt ggccaaggat ctgaaaagtt gaggtacatc
    27901 atatccacct caccatcttc aaaatagttg gttaaacttg atccatccac tcgcagaagt
    27961 ttgacattgg atacttctga agctaatacc ttatccaagg cgtagcttag gacagataat
    28021 tgaatatcaa tgccaatgta gttaatatca ggatttttca aggccatccc tgtgataaat
    28081 ccgccctttc ctgaaccaac ttcgatatga ataggacggt catttccaaa aacgtcatgc
    28141 caacggccct tggcatcttc tggatttaat atcacatagt gtgggttatt agctaagtgc
    28201 tcctcagcac cttttcgttt tctaactcgc attatttctt tctaaatatt tctctaaatt
    28261 ttctgagggc ataaatctcc tgattcacat gctccatgtc acgcttgtca aaacacttga
    28321 gaatttgtgt caggtgagaa aattgaccat accaaataat tttttgcata accttgtcat
    28381 tatttttata gccataataa gacagccatt ctgaccaacg agaccgtgga atatagtggc
    28441 tcaacaggta agcaacatca tacatccgat cagttagacg aacagaatcc caatctacta
    28501 aaaaaatcat accactagta gtaatcaccc aattgctatg tttaatatct ccatgcacaa
    28561 tcgttgctac ttctgatttg aactctggta agctccgttt taattcttta acgatagctt
    28621 gtaagtatga attttgctga atttgcaagg gtgcattttg ctcaaaatca accaataaat
    28681 cgtatgggtt ttcaatctta taattgagct gaagcagttg attgactaat tttttagatt
    28741 tgtgaaggcg caatagaata tgaatgattt gcttactgtt catatcttct ttggtcaatg
    28801 tacggccgtt aagccattct tgggcactca tcatatcacc attgcccatg cgtttggccc
    28861 aaagtaactg tggcgcaatc tgttcttttg ctaaggcagg tagaataggg gtcgtattta
    28921 attttataaa gacacattcc ccgtttggat aagtgccttt ataagctttg ccacttttcc
    28981 cacgtaaggg agtcaaggta agttcttgtt ccgtcgttgt caccttatcg ccctcctttt
    29041 ctatctttta tagtcgttta tccctatttt acttgtttta ggctacttag tcaatgatct
    29101 tctttaactt ataaggtaga tatatacaag ctatgaaaac catacctaca atcaaaatga
    29161 gtgcttttgg cgctgatgag caacacagca tattgacgat taacattaaa aagcttaaac
    29221 ctcgtaaaaa acttaacaca tttttcttct tgctccgact attttcagga taaagactag
    29281 tcatataatg gtaatcgtag tgataataaa gtgaaagtaa ttggaataca actaaatagt
    29341 taaaaatgag tgctaaactt actgacaaat aaagattatg gataaaaaat acagataatg
    29401 agcttaatag cattagtcgt aaaaataagc ccaaataatc tgaactacgt aaaaaggctc
    29461 tagcataaag ggacagccaa aggtttgaag gagtttgctt aactaatttt aaaagaggat
    29521 ttagataagt tctttctttc acttttgtag aaattccttt gactgttgta aaaagagaat
    29581 aaaactttaa aatactttgc ttgcgattgc tttcaaatgc gacagctttt gcccaatcta
    29641 aacgatttcc tctcaaaaaa tatcttgtct ttcgactaag cactactctt tttagtgcca
    29701 ataatatcaa aactaagata ataaaaataa gtaaagacag acctagacgt ctaaaaatag
    29761 gatataaaaa gagcaataca gcagtctgca aagttcccca aagcaaaaaa gagagtcgct
    29821 cagcttgttt gatataagaa atcacttctt cttcttttgg aagtaagaaa tgctgatctg
    29881 cctcttctag atacgttgct atagatccca tactgagcaa taatgggatc aatatcccaa
    29941 gacaaacctg aataggtaga tgattcgttg gaaaatggtt tagtagctga ccatactgca
    30001 ccatagcaaa gcctaataaa aacatcaaca ccaaaacaaa gtgatcattt aagacgtaac
    30061 gaaggtattt gttttgttgt ttttgaaagt cttgacggcg tttcagaaat aatgctttca
    30121 tacttaatcc tcttttgtta atgcaagata gatatcattt aagctcgctg aacggtcacc
    30181 aaaagcttct tgcaagtcag caagagttcc ttgggcacga acttgtccat gatgcaaaat
    30241 cacaaagcga tcacacattc tttcagcaga gtccaaaaca tgtgtactca tcaaaataga
    30301 ttttcctttt gctttttcga cttctagcgt ttggattaag tctgaaatag ctaaagggtc
    30361 taaccctaag aatggttcat caagaataaa tagacttgga tcaatgacaa aggcacaaat
    30421 aatcatgact ttttgtttca tccctttaga aaaattgaca ggaaaccatt caagtttgtc
    30481 agttaaacga aacatttcca agaaaggttg tgctcgtttt tgtgccactt ctaagtcgat
    30541 atcataagcc atagctacgg tgttgatatg ctctgataag gtcaattctt catagagact
    30601 aggagtttct gggataaaac ctattttttg acggtaagca actgcatttt ctgctagagt
    30661 taaaccatca atagaaatac ttccttgata aggcttcaaa aagccaataa tttcgttgat
    30721 agttgttgac tttccagcac catttagccc gatcaaaccg actaactctc cattgtctac
    30781 agaaaatgag acatcgttta aaacagggat attgtgatat cctcctgtta gatttttaat
    30841 gtttaacata taatttcttt ctagtttttg atatacttat aatatattat aacaaattca
    30901 agtagagaag gtgatataaa atggaaaatt gtattttttg cagcatcatt caaggggata
    30961 tcccctcttc gaaagtctac gaagatgagc aggtcctcgc ctttttagat atctcacaaa
    31021 ctacaaaagg gcatactcta gtcattccta agcaacatgt tcgtaactta ctagagatga
    31081 ctgctgagac agctagtcat ctctttgctc gtattcctaa aattgctcgt gctatccaat
    31141 cagctactgg cgctactgcc atgaatatca ttaacaataa cgaagcctta gcgggacaaa
    31201 ctgttttcca tgctcatgtt catctcgttc ctcgttataa tgaagaagac ggtatctcaa
    31261 ttcaatacac cactcatgag cctgactttc ctgtcttgga aaagctcgcc cgacaaatca
    31321 atcaggaggt tagttcatga aagttaaaac cgtgatagcc gtcggattat tatcttttac
    31381 cgcttacaaa gcatatcaaa aacgttgtac cataaaagag ctgttatcca tcagtagaca
    31441 agcaaaagat gctgcccaac ttgatttaga taacattaaa gcaaaccttg acctcattca
    31501 cagtcaagga aaagtaattc aaaatattag tcaggacttg gcccataaat ggcgctactt
    31561 taaccaagag acacaagcac acctcactga aatccaaaat cgtatggcca aatatcaaga
    31621 agatagtgag ctaatttcta gtgaatcacc tacttgccaa accgtcattt taactaacaa
    31681 ccattccaga tagtattatc tccctcatat actttatttg aaatcacaga cagctatcat
    31741 ctttgatacc tgtctttttt atattcaaaa tcggatattt taaacataaa aaccctcaga
    31801 acgttaggtc tgagggttga tattagcagg aggaactaat gatccagacc ctgatgagct
    31861 agactcatca gctgctaaag catctgatga agaagacggc gtagttggcg tatggcttga
    31921 agcagtagag tcctggtctg tactagtact ctgataagat gagccagtat ctactccact
    31981 tgaataatta gcgtaagagc tatgactatc agaataagat ggagcctggc ctgaagagtc
    32041 atagttgttg tttactgtct gagacttagt tgacccatac aaattttcat aaacagtagc
    32101 atttgttttt aattgactaa ccttatgaag tcctaattct gttcggatac gattttggat
    32161 ttctaacaaa tgattagagg taacaatttg gtatgatcca ccatctgata aagtggcatc
    32221 ttctcctttt agttgataag tcttaatggt tctaagtgcg tcacgataac ctaatagact
    32281 agggatagtg cgagaagaga tttcgatatt cgtttgcata ttactactta cagcagataa
    32341 aatcttccga taagagctaa tgctatcaag agcaaggatt tttttcaata ccttttgaat
    32401 gacttcacgt tgacgctttt gtcgaccata atctccctca ggatcatcat aacgcatacg
    32461 agcataaacc aaagcttgtt caccgttaat tttgtgtgtt ccaggcgcaa cagtagcttg
    32521 atattcaggt tcgttttcag caatcgagat aggaaaatca aactcatttg taactgtaat
    32581 ccctccaact gcattcacaa gatcaataag gccttgcata ttaatttgaa catagttatc
    32641 aatggtgata ttcaaaagat cttgcacggt cataatagcc atctgagcgc cacctgctgc
    32701 ataagcagcg ttaagcttag cttcaacacc attcatttca ttatttttgg gtccagataa
    32761 cgtggttaag gtatctcgtt ctaaactagt catagttgtt ttcttggtct ttggattaac
    32821 cgtaaccaaa atcatcgaat cactgtttcc ttcccacttg gaggcacgct ctgaagagcc
    32881 tgtatcaaca cccatcaaca agatagaaaa agctcttgtt tgtttaatgg catcactttt
    32941 ctttgaagat gtcgaaaaat ctttaaaggt ctttgataat tctcctgttg agaaggtata
    33001 agcactagtt agatagacac ctaatgccaa gacagttgtt aacacaatag ctgtgaacat
    33061 taaaactatt ttttttccaa ttttcatcga ttcacttact gacttacaga tttacgcata
    33121 tgataaacat ctaagtcatc tccatttttt gatttgatgt cgttttttcg catactttca
    33181 atacgaaaac catacttttt atacaggtaa atagccttag tatttcttgc ttgaacgtcc
    33241 aacttaaggc tttcgatata agggttttct tcagcccaat caagagcaat ctctaacaat
    33301 aattgaccga taccataacc acggtaagtc ttagcaacta acataaatac atctgcttca
    33361 acttggcctt gggataatac ttccccagaa agatttaaaa gccctactac tttttcatct
    33421 aatctagcta gcaggcaaaa atcaataaaa gaggtttgac ttcttgataa aaagtctgac
    33481 aattcttgag gagtagcctc taatatagtc tctacgcctg ttataaaatc tgtttctttg
    33541 gcagctgccg tcactaagga aagtacagct tttgcatctt gaggtacgcc ttcttcaata
    33601 acgagacttt gctgaatcat gtgatattat ctccagaagc tgacgagagc gctcaccatg
    33661 cgctaacaag tctagttgac gacctttgtc tcgtttagta atggtaattt gcaaatagtc
    33721 ttgtaataat ccctctccta ataattctcc ccactcaata acggtaacac cattaccaaa
    33781 aagaaaatca tctaaatcaa tagagtctgg atcatcacca acacggtaaa tatctaagtg
    33841 ataaagaggt agacgtcctt catattctct aacaatagta taagttgggc ttttgatcat
    33901 ttgactaatc cccatccctt tagcaatacc ttttgccaat gttgttttac cggcacctaa
    33961 gtcgccagac aatacaatca catctccaat agacaaataa gtacctaggg tttctccgta
    34021 agctttaaga gtatattcat tttcactata aaacatagca acattatatc agaaaaaaaa
    34081 catacttcca agcactacct agaagatgac tcaaataagg tattcgtaaa gtaaaaacgc
    34141 ttctttatat taaaggttaa aatcaattaa agaagcggca gttagtagca aaataagtaa
    34201 attatttggt tataagatag ttaatatgat gaaatttaca atgaacaaga aggttgctcc
    34261 ccaaataata gggtgaatat cttttgtttt tccctcaaca acttttacta gacaataaaa
    34321 aataaaggca gcggcaatac cataggaaat agagtaacac agcggcataa agaaagctgc
    34381 aaaaaaagct ggaagagcat ctgcaaattt actccaatta acatcaagaa aagaagacac
    34441 catcatgaca cccacaacaa ttaaagctgg agccgtagca gcagctggga caatacctac
    34501 aagcggtaat agcaatattg ataataagaa gcatactgcg gtggagactg ctgttagtcc
    34561 agtacgtcca ccttcagcaa ttcctgctgc tgattcaaca taggtagtcg tatttgaagt
    34621 tccaaccaaa gccccaatag aagtaccgat agcatctgca aaaagcgcac gatccatttt
    34681 tgaactaaag cctatactat tttccaaagc attctcatcg tcttgagaga aaatacctgt
    34741 tcgacgacca gttccgataa aggtaccaat tgtgtcaaaa gtatctgata gactaaaagc
    34801 aaaaatagtc atgaaaacta gcggtaaacg acttgaatcg ctaaaaagag aactcaaacc
    34861 atcgaaagct gcaaggaaag ttgtacctaa ttcagtccaa gcttcaccaa tatggctgat
    34921 cccaaaattg aggttggaca catccactat tcctaaagga atacctacaa gagttgttgc
    34981 gacaatacca attaaaatag cacctctaaa atttcgaatc acaagagctg tcgttaaaag
    35041 taaaccaaaa atagcaagta atacactgga atccgtaaaa ctagaaatcg taggtacaac
    35101 tccaccattg gcgtctacaa ataatagacc atctgcaaat gttttagccg atgctttagc
    35161 cggttcaacg ccatttacca ttactatatt ttcagcagag atagaaaaag taatgatatt
    35221 tgcgttttta aatcctaaat aagctacaaa gacaccaatt cccccaccaa tagcatgctg
    35281 taaactaact ggaatcgcct tgatgatact tttacgaaac ttggttacgg taataaaaat
    35341 attgaataat ccacaaatga aaaccattgc caaggcttct tgccatgaaa agcctaaagc
    35401 aaaaacaact gtataagtga aaaaagcgtt aagtcccatt cctggtgcca gcgcataagg
    35461 cacattggca aataatccca taattaaggt tgatatggct gctgcgataa tcgtagccaa
    35521 aaagacagca ttagagggca tccccgctgc acctaaaata cttgggttaa caaacaaaat
    35581 ataggacatg gcaaaaaagg tcgttaaacc agccataatc tcagttgaga cagttgtccc
    35641 attttcgctt aacttaaaaa acttttccat tgaaatggag tctccttaat taaatagtag
    35701 gtaaaatcaa aaagcgctta tcactagata agtctttttg acacctcatt attattgtta
    35761 ttgttcgcat taaaatgaac aataacaata tgttaccatt tttttgttca cttttcaacg
    35821 tatataactt catttattca ttaaaaaaac agttatccta tcttttttac taatgaatac
    35881 gcttaactta tcttttctct ttatcttgga gcaaaatttg ctataattta attatgacta
    35941 aaaaattgat tgccattgat ttggatggaa ccttattaca tcatgacaac accatctcta
    36001 cctatactca aaaaaccatc aaagctgtcc aagacaaggg ccaccacgtc attatttcaa
    36061 caggccgtcc ttaccgcatg gcactggact actatctgca gctcaattta aagaccccaa
    36121 tcatcacttt taatggggcc ttgacccaca tgcctgaaca aaaatgggcc tatgaacata
    36181 atgtcacttt ggacaaaggc tacctactaa ggttactaca atatcaggat gatttccaga
    36241 tggattttat tgccagtgag tatcgaaaaa atgtctacat caccatgacc aatccagaaa
    36301 gtatcgaccc gcaactcttt ggtgttgatg aaattactca ggacatggca ttagagatta
    36361 ccaaaatcac tcgaaatcca aacgccttat tgatgcaaac gcgccacgaa gacaagtatg
    36421 ccttagctaa aaacatgcgt gctttcttca aagatgaaat tgaaattgat tcttggggag
    36481 gccctctcaa cattcttgaa atttcgtcta agaatgtcaa taaagcttac gctctgaact
    36541 atctccttgg aatttacaat atggataaaa aggatttaat cgcctttggt gatgaacaca
    36601 atgacactga gatgctagct tttgctggaa ctggttatgc tatgaaaaat gctagccctg
    36661 tgctactgcc ttatgctgat cagcagctta atttttccaa cgaagaagac ggtgttgcca
    36721 aaaaattgga agaacttttc ttgtagtagc aaacgaaacc actatttttc agaaaatggt
    36781 ggttcttctt ctgtcaacag ctatcaaaaa atgaaaatca ttttaataat ttcaacattt
    36841 ttcagcatat ttttgtttta aacagcttga aaacaccttt aatatcaata atctgcctat
    36901 ttaatcctaa attctgaaaa ttttttcatg ttttgtacta tttttccgaa agggcttgat
    36961 tttttagtga aaacgtttta gaatagaaac gttcttgaat ttcgtttaag tgaaaaagaa
    37021 ttgccaaaat ttagttttgg aaggagatta ttcttcttca tttcaacgaa aaatatttta
    37081 aaggaggaag aacaagaatg ggtatcggta ttattattgc cagccatggt aaatttgctg
    37141 aaggtattca tcaatctggt tctatgattt ttggtgaaca agagaaagtt caagttgtta
    37201 ctttcatgcc aaacgaagga ccagatgatt tgtatggaca cttcaacaat gctatccaac
    37261 aatttgatgc tgatgatgaa atccttgtgc tagctgacct ttggagtggt tctccattta
    37321 accaagctag tcgtgtggca ggtgaaaatc ctgaccgcaa aatggcgatc atcactggtc
    37381 tcaacttgcc tatgcttatt caagcttaca ctgaacgtct tatggatgct ggtgcaggta
    37441 ttgaacaagt tgctgcaaac atcattaagg aatctaagga cggtatcaaa gcccttcctg
    37501 aagaccttaa cccagttgaa gaaactgctg caactgaaaa agttgttaac gcacttcaag
    37561 gagctattcc tgctggaact gtcatcggag atggtaaatt aaagatcaat cttgctcgtg
    37621 ttgacactcg tcttttacac ggtcaagttg caacagcatg gactccagct tctaaggctg
    37681 accgtatcat tgttgcttct gatgaggttg ctcaagatga ccttcgcaaa caattgatca
    37741 aacaggctgc acctggtggt gtcaaagcta acgttgttcc aattagcaaa ttgattgaag
    37801 cttctaaaga tcctcgtttt ggtaacacac acgcacttat tcttttccaa acccctcaag
    37861 atgcccttcg cgcggttgaa ggtggtgttg aaatcaacga attgaacgtt ggttcaatgg
    37921 ctcactcaac tggtaaaaca atggttaaca acgttttatc aatggacaaa gaagacgttg
    37981 ctacttttga aaaattacgc gacctaggtg ttacattcga cgtccgtaaa gttcctaacg
    38041 attctaagaa aaacttattt gagcttatcc aaaaagctaa cattaaataa gtttcaaacg
    38101 ctataaggtt ttaaaacgat gactagctaa cttattagca aaaagtcctc gtttactata
    38161 ctttgaaagg attacaacat gtcagatatt tcgattattt ctgcaatttt ggtcgttatc
    38221 attgccttct tcgctggtct tgaaggtatc ctcgaccaat ttcaaatgca ccaaccactt
    38281 gttgcctgta ctttgattgg acttgtaact ggacaccttg aagctggtgt catccttggt
    38341 ggtacacttc aaatgcttgc tcttggttgg gcaaacatcg gtgctgccgt tgcccctgat
    38401 gctgcccttg cctctgttgc agctgctatc atcatggtca aaagtggcga ctttactcaa
    38461 aaaggaatta cctttgctta ctcaacagct atcccacttg ctgttgctgg tcttttcctt
    38521 acaatgatcg ttcgtacttt gtcaactgcc cttgtacacg ctggtgacaa agctgccgct
    38581 gaaggtaatt tcgcaggtat tgaacgcttc cactttattg cccttcttct tcaaggattg
    38641 cgtatcgctg tcccagcagc tcttcttgtt gctgttccta cttcagccgt acaatctgtt
    38701 ttgaatgcta tgccaaactg gttgaacgaa ggtatgcaaa tcggtggtgc gatggttgtt
    38761 gctgtaggtt atgctatggt tatcaacatg atggctactc gtgaagtatg gccattcttc
    38821 gccctaggtt ttgctcttgc agctatcagc caattaaccc ttatcgctat gggtgttatc
    38881 ggtgtagcaa ttgccttcat ctaccttaac ctttctaaaa aagggggtaa cggtggtaat
    38941 gcagcaggtt cagctgatcc aatcggcgac atcttagaag actactagaa aggggtaaga
    39001 acaaatgact gaacaaatta aattaactaa atcagaccgt caacgtgttt ggtggcgttc
    39061 acaattctta caaggttctt ggaactacga acgtatgcaa aacatgggct gggcttatgc
    39121 acttatccct gctcttagaa aattgtatac gtctcctgaa gaccgtgcag ctgctcttga
    39181 gcgccacatg gaattcttta acactcaccc atacgttgca gctccaatca ttggtgtaac
    39241 acttgccctt gaagaagaac gcgcaaatgg tacgccaatt gatgacaagg ctatccaagg
    39301 ggttaaaatc ggtatgatgg gacctcttgc tggtatcggt gacccagtat tctggtttac
    39361 ggttcgtcct atccttgggg cacttggtgc ttctttggct tcaacaggta acatcgttgg
    39421 tccacttctg ttcttctttg gatggaacct tatccgtatg gccttcttat ggtatactca
    39481 agaatttggt tacaaagctg gttctgaaat tactaaagac atgtcaggcg gtatcctcca
    39541 agacattact aaaggtgctt caatccttgg aatgtttatc cttgcagtgc ttgttcaacg
    39601 ttgggtatct atcaacttta ctatcgacct tcctggaaaa caattgtcag atggtgccta
    39661 tgtggtcttc ccagatggcg ctgttaaagg tgctgagttg aaaactatcc ttgccaacgc
    39721 tattggcggt atgagccttg ataaagtcca agctcaaacc cttcaaggac aattggactc
    39781 tcttatccca ggtttagctg gattactcct tacattcctt tgcatgtggt tattgaagaa
    39841 aaaagtttct ccaatcgcaa tcatcatcgg cttgtttgca tttggtatcc ttgctcacct
    39901 tgcaggtatt atgtaatcaa ccaatggaag tctgagatga actcaggctt cttttttatg
    39961 ctttatgtca ggaaaattcc acttaaaata tggtataata actacaacta cgcaatgaaa
    40021 ggaacttaaa tggctcaatc tttaaacact agtgtcgaat acaagacaaa agctgtctcc
    40081 taccttggaa tgggaggcaa agttggtcat attttactcg gtgacaaggc ccttgaattt
    40141 tacaacgata aaaatgtgaa tgattatatt caaattcctt ggacagctat caatcacatc
    40201 ggggctaatg tttcaagaaa aaaagttagc cgccactttg aaatttttac ggaccaaggc
    40261 aagtttttat ttgcttctgg agactctgga aaaatcttaa aaatcactcg tcaacatatt
    40321 ggtaatgaga aagtgattac attaccaacc ttgatgcaaa cctttattaa caaatttttt
    40381 cgacattaaa aaaataatga gcagtgccga tttatcattt caagaaaaca aagaatagta
    40441 gctctaaatt gctatttagt ggaaaagatt ccctcatttg agtttacttt ttcttgtttt
    40501 ttgttataat agtcctaacg gataagtaat accttttttt cattcagaga gtctgtggat
    40561 gctgtgaaca gatagggaaa atgatatgaa attctaccgt gtcatcaata aaatagagat
    40621 taagtgcaca gattgtgaag ctggatggaa ccgcgccaaa gcgctccagc atcttcataa
    40681 gctgtgcttt ttctatcgtc agagaatcac aagatccaac tgtcttactt agccttgttt
    40741 cactgacagc tactaataac tatcttaaag gagcttctgt atgctagatc ttaaacgtat
    40801 ccgtaccgat tttgacactg tcgctgccaa attaaaaaac cgtggtgttt ctgaagacac
    40861 cctgacccat cttaaagaac ttgatgaaaa acgtcgtact ctattagtgc aatcagaaga
    40921 attaaaagca gagcgtaata ttgcttctgc tgccatcgct caagccaaac gtcaaaaaga
    40981 agatgccact caacaaattg ctgatatgca aaaagtctct gcagatatca aaactattga
    41041 caatcaacta gtagctatcg accagcaagt tgctgacatc atcactgttt tacctaatac
    41101 tcctcacgat tctgtccctg ttggagctga cgaagaagac aatgtcgaga ttcgccgttg
    41161 gggaacgcct cgtgactttg acttcgaagt taaggctcat tgggatctag gcgaagatct
    41221 tgatatttta gactgggaac gtggagcaaa ggtaactggt gctcgtttct tattctataa
    41281 aaatcttggt gctcgtttgg agcgtgctct ttataacttc atgctggatg aacatatcaa
    41341 agaaggttat caagaaatca tcacacctta catggttaac cacgattcca tgtttggtac
    41401 aggacaatat ccaaaattca aagaagacac ctttgaatta gcagatacca actttgtcct
    41461 gattccaact gctgaagtgc ctttgaccaa ttattaccgt ggggaaatcc tagacggcaa
    41521 agaattgcca atttacttta ctgcaatgag cccatctttt cgttctgaag cgggttctgc
    41581 gggtcgtgac acacgtggcc ttatccgcct acaccaattc cacaaagttg aaatggttaa
    41641 atttgctaaa ccagaagaat cttaccaaga actagaaaaa atgactgcta atgctgaaaa
    41701 tattcttcaa aaacttggtt tgccatatcg cgtcatttcc ctttgtactg gagacatggg
    41761 cttctcagct gctaaaacct atgaccttga agtctggatt cctgcacaaa acacctaccg
    41821 tgaaatttca tcatgttcaa atacagaaga tttccaagca cgtcgtgctc aaatccgtta
    41881 ccgcgatgag gctgacggta aggtcaaact tcttcacacc cttaatgggt caggacttgc
    41941 tgtcggtcgt accgtagcag ccattttaga aaactaccaa aatgaagatg gttctgttac
    42001 catccctgaa gtactccgcc cttacatggg tggcgaaacc gtcatttcac ctaaataata
    42061 aactcacccc agagatcatt aaagtgattt ctggggttta ctattttaaa gagccaccac
    42121 atcacttgaa actcactaca ttgccccttt aacaacactt ttcttcacac tagtttatca
    42181 aaagtcttat tagtataccc atttccttat ttacaagact agttaaaaac ccttttggaa
    42241 aggcctccct tagcttgata aacacgtagg gagactccaa aaggatattg ttaatattta
    42301 cgaaagcgtt ggtagcgctc atctaataat tggtctaatg gcttagcttg caaactggtt
    42361 atttgttcga tgaggttagc tttgatgatg tcaacgattt cacttgaaaa ataaccatgt
    42421 tctgggataa tacgatctac tatgcccatt tgatacaatt cgcctgcggt aattttcatc
    42481 aattcagcag cctctgtcgc tcttgaacca tctttccata aaatagaagc aaaaccttct
    42541 ggactaagga ctgcatacat ggtattttca agcatccaga cctgatcggc aaccgctaag
    42601 gctaatgcac caccagagcc tccttcacca ataatgatag cgataatggg aaccttgaga
    42661 tcactcattt ccatcaaatt tttagcaatg gcctcaccct gtcctcgttc ttccgcaccg
    42721 acacctggat aggctcctgc agtattgata aaggtgacaa cgggacgtcc aaatttttct
    42781 gcctgtttca taaggcgcaa agctttacga taaccttctg ggttgggctg gccaaaattc
    42841 cttgtcaaat tatcctgtaa attcttacct ttttgaatac caatgaccgt aacaggttgt
    42901 cccgccaaat aagctaaacc acctacaatg gcaccatcat ctgaaaaatg gcgatcgcca
    42961 tgcagttcca taaagtcatc gaaaataagg ttggcgtaat ccaaagttgt taaacgccct
    43021 tgatcacgcg cttcttttaa aactcttgat acatctgtca ttggccacct ccatgaaatg
    43081 ctactaagtg ggcaatcttg tctcgcaact ctgttcgttt cacaatagca tccacaaaac
    43141 catggtcttg taaaaattct gctttttgga aatcatctgg caagttttca cgaactgtgg
    43201 tctcaatgac acgacgacct gcaaagccaa ccaaggattg aggttctgcc aaaataatat
    43261 ccccttccat ggcaaaacta gctgttaccc caccagtagt tggatctgtc aaaatagtga
    43321 ggtaaaagag gcctgcatta gaatgtcttt tcacagctgc agagaccttg gccatttgca
    43381 tgaggctcat gataccctct tgcatacggg cgcctcctga agccgtaaaa atcaccaccg
    43441 gcagattttc ttcaatagcc aattcaaaca atcgggtaat tttttcccca acaacagttc
    43501 ccatactagc cataataaag tgagaatcca taatagcaag agcaatttgt tgtcctttaa
    43561 ccatagcttt ccctgtcaaa acagcttcat gcagacctgt cgtttccttg gctttttgta
    43621 atttttcctg ataacctgga aaacgtaacg gatccttggt ttcaatactt gtaaataatt
    43681 cctggaaaga gccttcatca actgttaagg tcagccgctc ttgggcagaa atcctaaaat
    43741 tgtaagaaca ggttgggcaa atctttgcca atcccaaatc tttcttataa atcatgtgct
    43801 tacaagctgg gcatttcgca aagagttcat ctggaacttc tgggacatta tggctgacag
    43861 atcctttgag gaaattattg ggagtaatac ggatgtattt atctttttta cgaaataaag
    43921 ccatattttc tcctaatctt tattgtaatg tggcaggaac gtttccatca agaaagaggt
    43981 atcataatct cctgcaatca ctcgcttatc tgaaatcaaa tcgagctgga agtctgtatt
    44041 ggtgataatg ccttcaattt ccaattcaac taaggcacgt tgcattttca tcaaagcgtc
    44101 aaatcgattg cttccatgaa cgatgatttt agcaatcatg ctgtcataat aaggaggaat
    44161 ggcatagcca ttgtaaactg ctgaatcaac tcgtagtcct acaccaccac ttggcatata
    44221 caagtctgta atctttcctg gactcggtgc aaagttaaaa gcagtatttt cagcattaat
    44281 acgacattca atagcatgtc ccgtgatagt gatgtcttct tgattaatcg ccaaaggctg
    44341 acctgctgca attttgattt gctctttgac aatatccact cctgtcacaa attcggtgac
    44401 aggatgctca acttggatac gggtattcat ttccatgaaa tagaatttct cgctgtcttc
    44461 gtccaacaaa aactcaatgg ttcccgcatt ttcataggct acagctttag ctgctctaac
    44521 cgctgcttgc cccatttcgt gtctgagggt attgccaata gcaatggatg gactttcttc
    44581 caagactttt tgattatgac gctgtaacga gcaatcccgt tctcccaagt gaatgatgtt
    44641 accgtaagcg tctcctaaaa tttgcacctc aatatgtcta gctgggtaaa ttactttttc
    44701 caaatacatg gcgccatttc cgaaagctcc caaagcttct tgactggcag cattgaaagc
    44761 cgcctccaaa tctgcttctg tctccacttt acgaatccct ttacctccac cacctgccga
    44821 tgcttttagc atgacaggat aaccaatctt attggcaata gctaaggctt cttgagcgtt
    44881 ataaacttca ccatctgacc ctggaataac gggcactcct gccttaatca tttcagaacg
    44941 agcattgatt ttatcaccca ttttatccat aaccgatgcg gatggaccga taaatttaat
    45001 attcatctct tcacacatgg tcgcaaactt tgagttttca cttaaaaagc caaaccctgg
    45061 gtgaatcgct tgggctcctg tcacaatagc tgctgacaag acggaattca tattaagata
    45121 ggattccttg gaacgggcag gaccaataca gatagcctca tccgccaata tcgtgtgcag
    45181 agcttcctta tccgcttccg aataaactgc aactgtggaa atccctaatt ctcgtgcagc
    45241 acgaatgata cgcactgcaa tttcaccacg attagcaatt aagatttttt taaacataag
    45301 ggtttcttcc tccgcagaac aatcattctc attgcccaca ggcaaaggtt aatgttccac
    45361 ttgctgctag cttgccatca acttctgccc tggcttcaac gacagcaatg gtaccgcgac
    45421 gcttgataaa ggttgctgtc atcacaagtt gatcaccagg gacgacttgt tttttgaact
    45481 tcactttatc cattccagcg taaaagacca acttgccttt attttcttct tttgacaatt
    45541 ctaagacacc agctgtttga gccaaagctt ccataatcag aacacctggc atcacaggat
    45601 agtgaggaaa atgcccgtta aagaaaggtt cattaatagt cacattttta atggcaacga
    45661 tatggtcgtc tgacacttct aacacacgat caaccaataa cattgggtag cgatgaggca
    45721 aagccgcttg aatttctcta atatccatca tttgatccgc accaatcctt gtccaaattc
    45781 aatgacatct tcatttgata ccaaaatttc tgtaatcaca ccatcacatg gcgctggcac
    45841 ttcgttcatc accttcatgg cttcgataat cacaagggtt tgtccttttt ttacagtatc
    45901 tccgactgcc acaaatggtg gcttgtcagg gctagctgca agataggcta caccgactaa
    45961 aggactttca acaatatcac cttctgctac aaaagattct gcttgtggtt gctcctctac
    46021 aggaacatcc ttaactgatg ctggactaga cgcttccgaa gcagttgaat tcggaacaag
    46081 ttgtacctgt ggtacaggca cagcatgttc ttgatttgat atcgatgcat tgaggtgttg
    46141 ttcgttttta ctaaagatta gctcaccttc atttgttttg aataaaaatt cacgtaggct
    46201 tgaagtatca aactgagcca tcaaatcttt gatttcttga atattcaacc tactcctccc
    46261 aacatttgaa agctaataca gcattatgac caccaaatcc aaaagtattt gaaatggcat
    46321 agttgatagc tgtttctttt ccttctccaa agatgacatt tgcttcgata tcctctgata
    46381 aagcttgtgt cccagccgtc atcggaacat agttatgacg catagcctcg atagtggcaa
    46441 tagcttcaat agcgcctgct gctccaagaa ggtgacccgt aaacgatttt gttgaagaca
    46501 ccggaacatc cttaccaaga acggctacaa ttgcttgact ttctcctttt tcattagctg
    46561 gggttgaagt tccgtgcgca ttgacataat taatagcact ggcttcaata ccagcttctt
    46621 gtaaggctaa gtggatggct ttacgagctc ctaatccctc aggatttgga gatgtcatat
    46681 ggtaggcatc gcaggtattt ccataaccca caatttctgc taagattgtc gccccgcgtt
    46741 cttgcgcatg ttctaggctt tctaaaacaa gcattcctga tccttctccc atgataaaac
    46801 catttcggtc tttatcaaat ggaatagagc ttctgcttgg atcttcagtt gttgagagag
    46861 ctgttaaact ttggaagcca gcaatggcaa acttggttat ggccgcctct gacccaccaa
    46921 ctatcatcac atcttgagtc ccaaatttaa tggcacgaaa ggcatcccca atcgcatcat
    46981 ttgaagaagc gcaggcagta ttaattgatt tacatactcc ttgagctttt aaagacatgg
    47041 cgacatttcc tgcagccata tttggtagcg cttttggcaa cgtcattggc ttcacacgtt
    47101 ttggcccttt ttcatgtaag cgaatcacct gctcttcaat ctccgcaatt ccaccaatac
    47161 ctgaagcaac aataacgcca aatcgatcgg aatcaatcat ctcaatattt aaatcagcat
    47221 gattaatagc ctctttcgct gcataaagag cataaagaga atatctatcg aaacggttca
    47281 aatctttttt cacaaagtat ttgtcaaatg gaaaatcctg aatttcagca gcattcttga
    47341 ctgcataatc agtcgtgtca aatttagtaa taggaccaat accaatttgg ccagctttca
    47401 gattgttcca aaacgtttca ggatcatgcc cgattggaga tgttagacca taacctgtta
    47461 ccactactct tttaaatgtc atttcactac gtctccttat tgcattgtca taccgccatc
    47521 aatagcgata acttgtcccg taatataatc ttgttccacc aagaagcttg ctaagtgagc
    47581 aacttcttga gcttttccaa tacgtttcat tgggatttga cttaagattt gctcttgcat
    47641 tttttcagga aggacacctg tcatgtcgga ctcgataaat cctggagcaa tagcattcac
    47701 gcaaatgtta cgagcagcaa cttcacgggc aacagacttg gtaaaaccaa tcattcctgc
    47761 cttagaagca gcatagtttg cttgcccaat attgcctgtt aaaccaacca cactagagac
    47821 attaataatt gctccttggc gagccttgat cattggtttt aacactgatt gagtcatgtt
    47881 aaaagcaccg gtcaagttga ttttcaagac gcgctcaaaa tcctcttccg tcattttaag
    47941 catcaattta tcattagtaa tgccagcatt gttaactaaa acatcaatcg aacctaaact
    48001 ttcgatagct tcattgacca tacgtttagc ttctgatgct tctgaaacat ccccagagat
    48061 ggtaacaact gtaacaccat agtcagtaaa actagcaaca agctcctcag agatagcaga
    48121 gcgaccattt aagacaatat tagctcctaa actggcgaat tgatgagcca ttgctaaacc
    48181 gatacctctc gttgagcctg tgataaatat attttttcct ttaatttcca tgaatgtcct
    48241 ctctatctaa aaataaacgt aagcttacca tgttttcaac actagtacat agtaaatttt
    48301 tatcaatttt cttcacaaaa cctgtcaaaa ccttacctgg tcctacctca atgaattgtg
    48361 ttatgccact ttctactaaa gtcgcaacac tgtcataaaa acgaacaggc tccatgactt
    48421 gacgggctaa tagttctggg atacggtctt tttccataat attagcttcg gtattaccaa
    48481 ccaaaggaat cttgaagtca ctgaagttgt atctttccaa ctccttagcc aacaagcggc
    48541 tagctggttc taacaaagca gtgtggaaag gacctgacac gtttaaaggg attaaacgct
    48601 taactcccct ttcctttaaa agttcaactg ccacgttcac agcatctgtc tgaccaccaa
    48661 ttacaatttg actaggagca ttatagtttg ctggagcaac cactccatgt ttagcagcta
    48721 tttgacagac ttcttcgatg acttgcacgt ctgtattcat aacggcaacc atctttccag
    48781 atctttgtgg tgctgcttcc tccatcaagc ggcctctctt agctactaag gatagggtat
    48841 cttcaaaaga gagtgcccct gatgctacca aagctgagta ttctcctaag gaaagaccag
    48901 ctaccatatc cggtttaacg tgatgtaagc ccaaaacacg gtaaatagca attgatgatg
    48961 tcaaaatagc tggttgcgta tagctagttt gattaagttt taactcgtca ctatcaatca
    49021 aacggcgcaa atcgtatccc aatacttgac tagcttgatc aaaggttttt cttacaatag
    49081 caaagttatc ataaaaatcc cttgccatcc ctaatttttg ggcaccttga ccggcaaata
    49141 aaaaagctgt ttttgtcatt atcattatcc ttcatgtgtt tatctacttt tctattgaaa
    49201 cagattgcca gcgcttagct tcattttgaa taacacgagc tgcaccataa taaatatctt
    49261 ttaaaatcgt ttcacagctt tcttcttttc tcacaagccc tgcaatttgg ccagccataa
    49321 cagatccatt gactacatcg ccttcaataa cagcatgtcg aagcgatcct gctcccattt
    49381 cttcaatatc agtagctgtt ttttgaccaa ttaaaaatgc tttttctgct ttagcgtaag
    49441 ctgaggtcaa tttattttta atagaacgga cagggtggcc cacaacctgc gcagaaatca
    49501 ccgtatcaat atcttttgct gctaagattt tatctttaaa attttggtgg gcattggatt
    49561 ctttagcaac aacaaagcga gttccaattt gaacagcctc tgctcctaac ataaatgctg
    49621 ctgctgcacc atgaccatca gctataccac ctgccgcaat gacaggaatc gaaaccgctt
    49681 caacaacttg tcttactaaa gacatagtcg ttaacttgcc aatatgtcct ccagcttcca
    49741 taccctcagc aatcactgca tctaccccaa gcttttccat acgtttggct agcgcaacgc
    49801 ttgggacaac aggaacaacg attatacccg cctggtgcag tctttccata tactttcctg
    49861 gatttcctgc gcctgttgtt actactttaa caccttcttc aatgaccaaa tcaacgatat
    49921 catcagcaaa aggagataaa agcatgatat taaccccaaa aggtctatca gtaatagctt
    49981 tgacacgatc aatattagct ttaacgactt ctttgggagc attgccacca cctataatgc
    50041 ctaaaccacc agcattagaa actgcacctg ctaaatcacc atcagcaacc caagccattc
    50101 ctccttgaaa aatggggtaa tcaatattaa gtaattctgt aatacgtgtt ttcataataa
    50161 ctttctataa aaaataagga gaataatttg ataatcaaac tattatagta agaagaaaga
    50221 gcgagctaga tcctaaaaag agtctaatcc caccctaatg gtttgattaa tacttattgt
    50281 ttttttagtg atgaacatga acataacagc agtaagcttt tcatagactt ctgatgttac
    50341 ttgtcacttt tatccttatt ttgacttttc ctcaacgtaa gcaacaaggt caccaacagt
    50401 atttaatcct tcttctgttt caatttgaat atcaaaagca tcttcaattt ctgaaataac
    50461 ttggaaaaca tcaagtgaat ctgcgtctaa atcatcaaat gtagtttcta gtgttacttc
    50521 ttctgtctcc ttaccaagtt cttcaacaat aatttcttgt actttttcaa atactgccat
    50581 gtttatttct ccttaaaaaa tataaatttg tttttataaa tgtgctaggc acatgaataa
    50641 ctagatttta acaattagac ttccccatgt caaacctcca ccaaaaccgg aaagtaagat
    50701 tttttgggta ccatctaacc taatctgtcc cttttgaaca gcctctgaca agaggattgg
    50761 gatactagca gcactagtat taccataacg catcatgttt tcaaggaatt tttcccgagg
    50821 aacatcaatc ttgcgtgcta ttttatcaag tatacgacga ttagcttgat gcaataaaca
    50881 atagtctatg tcatcttttg taatatctga ttgcgccatt agtgtgagga tgctttttga
    50941 cacatcccta atcgcaaaat caaatatggc acgtccatcc atctgaatag tcgctatggc
    51001 ttttttgcca attgagtacg gagatgaaag actagtttct cctgaaatta aactctgaca
    51061 tctcgcacca tctgtgtgta atgtttccgc taaaacatgt ttatctttac tggcttccag
    51121 tagcacgcca ccagctccgt ctccaaaaag aacggctgtc gctcgatcct gccagtttac
    51181 taacttagat aaagtctctg cacctattac cattccgttt tggtaggcac ctgatgcaat
    51241 aagcttatct gccatagcca aggcaaagac aaagccacta caagcagcag tcatatcaaa
    51301 agcaaaagca cttgtagccg caatagctgc ttgaactttc gcagctgttg atggcatagt
    51361 ggcatcaggg ctgatagttg caacaataat aaaatcaata gcattagctt ttaacccaga
    51421 ctgagttaaa agctgatcag caacctgaat agctaggtca ctagtcattt catctctaga
    51481 aatatggcgt tctgctattc ctgttcgaga aaagatccac tcatgactag tgtccattat
    51541 gctagctaaa tcattattag tcactaactg ctgtggaaca tagtgggcta cctgactgat
    51601 tttagaaaaa atcatttaaa ccaaatcctc caaaaattga tgtagattcc ctagtccacg
    51661 caccaatgcc tgcatctctt catcactcat atcagcaatg acatgtccaa ccatattttt
    51721 atggaacttt gcatggaggc ggtccaaaag tcgacccctt tttgttaatg acaggtaaac
    51781 aactcgccta tctgagcgtg atcgcgttct tgcgatataa ccttttgctt ctaatttatt
    51841 taagctagtg gttactgtcc ctaacgttac cattaattct ctggcgatat cacttggagt
    51901 cacctgatca tatttgccga taatttcaat agtgtgcatc tcttttaaag agacatcatt
    51961 aaattgactg gtttttaaac tcatctcttc aattaccaaa atacggttga agatatcaac
    52021 caagtagtga ttgattttgt catattccaa gcaaatacct cctaacaata aaactttgac
    52081 agtcaaatta tatcagagtt aaaagcactt tgcaagcatg agtctactta ccttgaaaat
    52141 ttggtcggcg cctttctcca aaagctatga caccttcttt aaaatcttcc ttgaaagcta
    52201 gctcctcttg aatagcaagc tctgccttag cataatcttc ccatcctgtg aaaaagcttt
    52261 gccagaccaa tgatttcatt ccagcataag aatttgaaga gccacgtctc aatcgcttta
    52321 aaagttgaag acaaactttg tctagtttat cagattctgc cgtacggtag acaaacccat
    52381 aatcgacacc tttatcagca gtaattcctt cacctgtcat cacaagatga gttgcacgat
    52441 taagtcctac tgcacgagtc aatagaaata aaccaccggc atccggtgct agtccaacat
    52501 ttacaaaagc ttggataaat tttgtttgag tactagcgat acaaaagtca acagctaaag
    52561 ctatattaaa agccgctcca gctacagctc catcggcgca aaggatgact ggttttggca
    52621 aatgcttgat tgcaaaagaa atttcttgta ccagttcagc aatcttgact agcgactgca
    52681 cattatcttt tgcaacagct tcttgcattt caactaggtc accaccaact gaaaacactt
    52741 ttccaacggc tttaattagt aaaaaacgca cagatgtatc gcgtttaact tctgctaatg
    52801 ctaccagaat ctcttgacaa attggaatat taaaaccgtt tgaaacctct ggacggttta
    52861 aagtcaatat cgcaagatca tctacaacat caaagatgat gtgtttaaac tgcataacaa
    52921 tcctcttttc tgataattta tttgactaag aaattatttc tctttaaaat catttgataa
    52981 tcaaatcaat tacctaatta tgatatacta aataaaccat tttgacaaga gaaaaaaacg
    53041 atatctataa aagaaaacgt tttctctaac tgttttgaca taaaaaaaac gtataacttc
    53101 gggaaaatta tcctgagatt atacgtttga catctttaaa tatcctctaa ggcatctttc
    53161 actttatcaa aaaaaccttt tttctttgga tgtaacattt tatcaccact cgcttctgca
    53221 aatgcttgca aggcttccct ttgagcgtca ttgagtttgg ttggggtcac aatattaacg
    53281 gtaacatgtt gatccccttg acctccacca cggagttttg gtgctccttt gcctttgagg
    53341 cggaaggttt tacctgtttg tgtcccagca gggatagcca tctcaacatc gccatgaacc
    53401 gttggaattt caacagtatc tcctaaggct gcttgagtaa aagaaatatc taagctgtag
    53461 taaatagtgg aaccattgcg ttcaaattgc ttacttggta agacattcaa aataacaaat
    53521 aaatcaccat aaggtccgcc attaaagcca gcttctcctt gaccttgtaa acggatttgc
    53581 tgaccagtct ctacaccagc tggaatctta acagacactt tatgagcttg cttttcatga
    53641 ccagtaccgt gacaggtttg acagggttct ttaatttcct taccactacc atgacaaata
    53701 tcgcaggtga cttgtcgacg catcatacca agtggtgttt gggtgtcaat tgtcattaca
    53761 cctgaaccat ggcacttacg acaagttact ggagcggtac caggttttgc acctgagcct
    53821 aaacaagtgc cgcaggttgc ttcgcgatta tagctaactt ctttttcaac accaaataca
    53881 gcctcttcaa aagataaatt aacacgatat tgcaaatcgt caccttgacg aggggcattt
    53941 gggtttcggc ttccaccgcc accaaagaag cttgagaaga tatcttcaaa accaccaaag
    54001 ccgcctccgt caaaaccacc aaagccgcct gctccgccac caaagccgcc ttgagcacct
    54061 gcagcgccgt attgatcata agcagcacgc ttttgtgaat cgcttaaggt ttcgtaagct
    54121 tcttgaacat ccttatattt ttgctccgct ccagcttctt tattgatatc tggatgatat
    54181 ttcttagaca tttttcgata agcttttttg atatcgtcct gagaagcgtc cttagaaacc
    54241 cccagacgat cgtaatattc tgtattgttc ataatgtaag ataccaagcc gtaaaacgac
    54301 tcaatgaaaa ataggaaatc cgacaaagat actctcgtat ctaggaggta tttctctttt
    54361 ttcgcagaat cgtaggcgtg ttcaaatccg caaaagagtc tttacacgct ttagcctgtg
    54421 ttcgaataat cgaacttgta ttcctttctt aaaatatttt gacgtcagca tttttacatt
    54481 ttatttagcc aaaaacagag gtttggtaca acctctgaat tcggatatta atgttactag
    54541 ataactaaat cattactttt ctgtaaattc gccatctaca acatcatcat tatttgctga
    54601 atcattagct tgtgcacctt ctgcaccttg tgctgcttgt tgagctgctg cagcttgctc
    54661 gtacatttta acagccaaag cttgcgcttt ttcatttaat gcttcaagtt tagctttcat
    54721 gtcgtcaagg ttgccagatt cttgcgcagc ttttaactcg tcaagagctg attgcgctgc
    54781 atcgcgttct gtatcaaagc ctttaccctc agtttctttg attgtttttt cagtagcaaa
    54841 gatagcttgg tcaacttcgt ttttaaggtc aacttcttct ttacgtttcg catcggcttc
    54901 ggcattagct tcagcgtctt tcatcatgcg atcaatttct tcttcagaaa gtccgtcgtt
    54961 tgatttgata acgatgtgtt gttccttttg cgtaccaagg tctttagctt ttacagaaac
    55021 aataccgttt ttatcgatat caaatgttac ttcaatttgt gggattccac gaggtgcagc
    55081 tgggatatca gtcaattgga agcgaccaag agtcttgtta tctgctgcca ttgggcgttc
    55141 accttgaaga acgtggatat caacggctgg ttggttgtct gctgctgttg agaagacttg
    55201 tgatttagat gttgggatag tggtgttgcg gtcgatcaat ttagtgaaga caccacccat
    55261 tgtttcaata ccaagtgaca atggtgttac atcaagaagg acaacgtctt tcacatcccc
    55321 agtgataaca ccaccttgga tagcagcacc catagcaacc acttcatcag ggtttacaga
    55381 tttatttggt tctttaccag tttcagcttt tacagcttcg acaactgctg ggatacgggt
    55441 tgatccacca acaaggataa cttcatcaat ttctgacaat gacaatcctg catctgaaag
    55501 ggcttgacga actggagttt tcgtacgttc tacaaggtcg cgagtgagat cgtcaaattt
    55561 agcacgagat aagctcatct ccaagtgaag aggaccagca gaaccagcag tgatgaacgg
    55621 taatgaaatt tgagtttgag ttacacctga caaatctttt ttagcttttt cagctgcatc
    55681 tttcaagcgt tgaagagcca ttttgtcttg agaaagatca ataccatttt ctttcttaaa
    55741 ttcagccacc aagaaatcaa taattttctg gtcaaagtcg tcaccaccaa gtttgttatc
    55801 acctgctgtt gcaagaacgt cgaagacacc atcacctaat tcaaggattg atacatcaaa
    55861 tgtaccacca ccaaggtcaa aaactaagat tttttcatcc ttgtcagtct tgtccatacc
    55921 ataagcaagt gcggctgctg ttggttcgtt aacgatacgt tctacttcaa gacctgcaat
    55981 tttaccagcg tctttagttg cctgacgttg tgcatcgttg aaataagctg gaacagtaat
    56041 aactgctttt tctacttttt ctccaagata gtcttcagca taacctttaa ggtattgaag
    56101 aatcattgct gaaatttctt gaggagtata ttctttacca tttgcagaaa ctttttcaga
    56161 agttcccatt ttagatttaa tagagattac tgtttctggg tttgtcactg cttgacgttt
    56221 tgcagcatca cccacgataa tttcaccatt tttgaatgat actactgaag gagttgtacg
    56281 attgccttct gggttagcaa tgatttttga ttcagtccct tcaagaactg ctactgctga
    56341 gtttgttgta cctaagtcaa taccaataat tttagacatg ttaatacctc ttattttata
    56401 atactttatt actttttatt tcaatttatc ttagtaagca ctcgaattat tttacttcca
    56461 attctaagca atcactatag tttaatcagc aagcgaaata acttctaact tgctatctag
    56521 tttactgtca ttacggacaa aaacgaaaac tcatttacct tagttataga caactaccat
    56581 cgctggtctt aacaaacgct cgtgcaattt atatcccttt tgaaagactt ctgcaatgct
    56641 atcggctgga tgttcatcat cggctgggag ggtctgaact gccatatgaa agttgtggtc
    56701 aaatgagtca acttctactt cttctacgcc ttcttccttt agtgcttgaa taaggctatc
    56761 acgagtcatt tctaaacctt ttttaacatc atctgtcaac ccttcaacag ccaaggcacg
    56821 ttctagattg tcaagcgatg gtaagattgc ttttgccaga tcctgagaac gatagcgttg
    56881 aagttgttga cgttcttcac tagagcgacg ctgtatattc tgcatttctg catgagctcg
    56941 caagtattta ttttcaaact catcagcacg ttcgtttgca agttctaact ctgatttttc
    57001 aggagtttct tcaataactt cctcaactgt ctcttcagtt tcagtggctt ccacttcttc
    57061 ttgtaaatcg tcttttttaa tttcttctga cactgagtgc ctccttttaa ataacttatt
    57121 gaacactgcc attatcagtg gacttcataa tggttagaat ttaggtatcg ataataatca
    57181 cctaatttag cagccaatac ctttccaata atgtttacca aactaacaga cctacgataa
    57241 tccatatcaa taggaccaat caaactcagg agtccaaacc cacggtacgg aatcaaaaat
    57301 ttgtgagtca aaactgacac atctgcaagt gcggcttctt gactatctgc cacttggaca
    57361 gaagccatct caccttcttt cagactttgc ctcaaagaaa ttgctacttg ctgttcatta
    57421 tccaaaaact gatacgttga tagatctgaa tacgttaaag aatttacctt gccagcaaca
    57481 aataccgttt ccaaaaacag ctctgaaaaa acataatcaa atagttgtaa aacattatcc
    57541 gtagtcacaa aatacttttg aacgatctga ggaatttctg tcctcaactt ataatgaata
    57601 tctatgacac tactatccag caagcgctcc tctacgatag ctttaaatgc tatcaagtca
    57661 cgtgtcaaaa agtttcttgg aatagcaaac tgcactgtca ctggcttaga ttcatctaaa
    57721 gtcatgactg ctagagcatc atggttgcta agctgaacaa catcaaaccc tgttaaacgt
    57781 tgacgagctg gctccacatc taaaataacg gatgtatagc ccgtcatctc cgctaaaatg
    57841 tgactagctt tttgaagcat gtcttctaat ttgaatgctt caaaatcaaa agtttttatg
    57901 acatgataaa tatcttgctc atcaatacta tctagcctga gggagtgctc tacaaaatac
    57961 ttaaagccag ctggacttgg catccgtcca ctagaagtgt gcgctttttc caacaatccc
    58021 aacttctcta gttttgccat atcattacga atagtggcgc tactagaatc aatcgttctc
    58081 tgtaaagctt tagaccctac tggttcatga gtttgtgtaa atagctcaac gattaaattc
    58141 aaaatatcat tttgacgttg tgtaatcaca aaccaaccac tccctttcgt ttagcactct
    58201 atttagtaga ctgctaattt ataattctat tatactcttt atgggacaca tgtcaagaaa
    58261 aaaactcaaa aaaattagca ctcttttata aagagtgcta atttcagtca tagtttgtta
    58321 aatcgttact ttcaatgacc tgaatcagtc gcctagcata ggttttatca gtataatgca
    58381 aatacttttg taaactttta gctggtgctt tatacccttt ttctgtagca agattacgat
    58441 acaaacgctt atcgacttct tttccctgcc gaagcattcg taaataatct ctaattgcac
    58501 tagcgtcatc tttataaata gcatatctca cgttttggtt ggtttgttta ggggacttta
    58561 gggtaatggc cgcttgtcct ggagttgctt tcttgctaaa aagattatga tacttagacg
    58621 ctagtaatgt ttttccatca tgggtttcca aaagaatttg agcaatcaaa atagatggtc
    58681 taataccata atattttgcc aatggtttaa cttctttacc catttttgta ataaattgtt
    58741 tttggctgta gttcaccctt acttctttat ctgcactagc tatcctttgg ctactcagta
    58801 agggacaaac aatcagcaat aaaaagcaag ctagaagcgt taaaaaatac ggaaacttta
    58861 gtcgttttct catcgtttct cctttaaagc agcaatgtac tcttccaacg ttaggttgta
    58921 ctgagccata taacgagcag acgccttgcc tacatagcgg taataccaat cctcataatc
    58981 aacccctgta ctagtctttt ttccttctgg aaagcgcaag acaaacccat aatcaggtgc
    59041 aattttttga actgctttag ataccgatgg gtcactggca tttaaagtat ctacagtgct
    59101 catgtcaata gcaagaccag tgtgatgttc actagcccct ggcggctgta aataggtttg
    59161 caccaaagcc tccgcagctt cttgtgtcaa tgttggatcg ttaggcatct cttttttaat
    59221 ataagattgg taaagctctg cttggtaagc tacggagcga tagcctgaaa taaggtgctc
    59281 ttgtgggtca atagcctgag ctgccgctaa aaaatcagca gtagcctgtt caatacgctt
    59341 gtccaccgac accccattca catcaaccaa ttctgggctc aattcctcag tcatatggtc
    59401 ccgattcact aaaatcaatt cccaatcttt tggagagact ttaggaagcc ctgtggactc
    59461 tttgctattt ttgaccactt tttgactgct tgcctggtga cttaaaggcg tcttggtggc
    59521 ctgcttctct ggcttaataa agaggtaaat acctccgaca aagagcagga caaccagtgt
    59581 ttgcaataat aatttaaaat gattatgctt catctgacat tgcttctatt atttcacggc
    59641 cacggtagcg ataactcata tctccaatgg ttttgatggt aaattgccca tcttcaaatt
    59701 cgacaacagt gacactgccg ttatcaatat attgtttctc acggtcagga tcgattagcc
    59761 acataaatgt tccaatagtc atcccatggc taaccacaag agcatttccg ccgccagcat
    59821 tttgaataga caaggcaata gcttcaaacc cctcccaaat gcgcttacga agaacttccc
    59881 atggttctgc ccaattagcg gtatctactt ccacgatgct ttctgccagt tcagaatagg
    59941 gaacatcacg taggttatca cgattttcaa aggcttttgt tcttggaagg acacctagaa
    60001 ataattctga atcataagtc ccttctagac tcccaaaaca ccactcacga atacgattat
    60061 ctttagtata aggcaaaaat tcgttttctg attctcttaa aataatttct attgtctgca
    60121 tggttcgacc tgaatcactt gaaaacgcag ccttaaatgg tatagttgca tcttttaaac
    60181 ctaagccaag ttctcgaata ccttcttctc ctttttttgt aagaggtgtg tcactccaac
    60241 cctgagcgcg accaatggta ttaaacatcg tttttccatg tctggcaata tacaaccttg
    60301 tttttgtcat ttcaacctcc taaactgtct tattaattat tatagcattt aaagaaaaca
    60361 cttgcaaaac acttcctgat ggctatttga gatcaaatag accactgact tattgtctat
    60421 tttattaaaa ataatgctat tgctacaatt caaatcatca cataaatttc caaacgatta
    60481 catttatgtg tttcgctcaa atatatataa caacagaccc acactacaac taaactgacg
    60541 ttacaaaatg atgtcaaaac agtaacaaaa tctaactatt tgttaagaaa atgatattaa
    60601 attttcacac aactatctta taatgaggat gcaaccaata aaaagataag acattttatg
    60661 ttgcaaaaaa ggctgcttgg aaacttccat gcagcctttt tttaatacct ttttccaaaa
    60721 atagctgaaa caagtacaat tacaattgcc gctcccaaaa tggacgggaa aatagccata
    60781 cctgccaact gaattcccca atccccaaaa agcctttgcc caacagctga ccctatgaga
    60841 cctgcgataa tattagtaaa acaacccatg gactggcttt tttcagtcat tttacctgct
    60901 atcatgccga taaaggcacc tacaattaaa gaccatatca tcgttaacac ctcctttctt
    60961 gtaaaatcct tttagaagaa ctgctatcca ttaaatgttc ttaactttag ttaattcctt
    61021 taccttcttc tttagtaagt gtttccgtgc ctgagtaaaa tagaaaaaca attccttcta
    61081 ttaagataga tagaccgaga acgactagaa gtcttcacac actaaataac ttaacaaact
    61141 ttatcacaca gctaatcgct aataatagtg tagacaaacg cgatggttca ttaaataccc
    61201 gtcagaaact cctgaaggtt ctaaagcaat acctgtcagt cttattttag catagatgat
    61261 ggtcttttta tagacggtca ctaacatgac atacaaaaag gcagcctgtg aaagaccgac
    61321 cgcctttttt tcagagacaa aatactttaa cttattgcta tcagcaacta tcaatctcgc
    61381 aatttttgca attcttgtgc caataattgt tgagcgactt gtggattagc ttgacctttg
    61441 gttgccttca tcaagaagcc tgtgaaagcc ttatcagcat tacgtttgcc tgatttgaaa
    61501 tcagccactg cagcttcatt atcagcaaag acttggtgaa taattggtac caaaacagcg
    61561 ggatcagaaa tctgaacaag tcctgccttt tcgacgtagg cgcgagctga gccaccattt
    61621 ttagccaaat gcacaaagac cttcttagcc attttagaag agattgtacc atcagcaatg
    61681 atagcaatca tctccaccaa attttctggt gtcagagcga tttcttcaat ggttttgcct
    61741 tctgcattta agaattgggc aatttctcct tgcaaccagt tagagacttg cttggcatcg
    61801 ccaccaagac ttactgcagt ttcaaagaaa tctgacaaga ctttggtagc tgttagctgg
    61861 ctagcatcat aagctgagag accaagttcc tcttcgtatt tagcacgacg ttgagctggg
    61921 aattgaggta attgagcacg catctcgtca atccaagcat catcaatctc atacaagggt
    61981 aggtctggtt ctgggaaata acgatagtcc gctgcccctt ctttgacccg catcaaaata
    62041 gtccccttat tcgcttcgtc atagcggcgc gtttcttggc gtatcacccc acctgaacgc
    62101 aagagtttgg cttggcgttc cacctcaaat tcaagccctt tacggacatt tgagaaggag
    62161 ttcaagtttt tcaattcggt ctttgttcca aattgttctt gcccgtaagg acgaagagaa
    62221 atattggcat ccacacgcat ggagccttct tccatcttga catcagaaat acccgtatac
    62281 tggatgattt ctttcagagc tgtcaaataa gcataggctt cttcaggaga acgcatgtcg
    62341 gcttctgaca cgatttcaat caaaggaact ccttggcggt taaggtccac ataagaataa
    62401 ccatctgtgc catgagtgtt tttaccagca tcttcttcca agtgtgcgcg ttcaatacga
    62461 attttcttgg ttgagccgtc ttccaattta atctcaatcc atccgttgta gccaaccggc
    62521 tcgtcaaact gtgaaatttg gtaagcttta ggattgtctg ggtagaaata atttttgcgg
    62581 tcgaaatgca tctctttatg gatgtccata ttgagggcaa gcgcagcttt tatgctcgca
    62641 tcaatcaccc ctttgttcat gactggtaag acccctggga aagaccaatc aatcacattc
    62701 gtgttggcat ttggatcctc accaaagtga gctgacgaag gtgagaaaat tttggaattg
    62761 gtatttaatt ccgcatggac ttcaagccca ataatggttt caaaattcat tacttgtcac
    62821 ctccaaaaat aatcggttgt tgcttgtgat aatctgtcac cgcttcaaag gctgctgctg
    62881 cctgatagat ggtttcttca gcgtatttcg gaccaattaa ttgaagccct actggcaagc
    62941 catcgacgaa tcctgccgga atagaaatac ctggcagacc agctaagtta accggaatgg
    63001 tcaataagtc ggccaaatac atggcaacag gatcatggtt gagtgtgtct aagccaaaag
    63061 caaccgtcgg tgttgttggg cctagaataa gatcataatc cgcaaagacc ttgtcaaaat
    63121 cttgaataat caaagtgcgc acttgaccgg cctttttgaa ataagcgtca taataacccg
    63181 atgacaaact aaaggttcca agcatgatac gacgtttcac ctcatcacca aagccttggc
    63241 tacgagtgtt aacatagatt tcatccaagt ttttagcatc gtcagcacgg aaaccatagc
    63301 gaatgccatc aaaacgttgt aagtttgaag acgcttctga cgaagcaata atataataaa
    63361 cagccacacc gtacttgcta tgtggaaggc tgacttcctc aacagtagct cctaaggctt
    63421 caaattgttt agctgccgca agaaccgttt ccttaatctc aggatcaatc ccttcgccaa
    63481 gatactcttt aggaagggca atcttcatgc ctttaatatc acgaccaatt ttagacgtgt
    63541 agtctgcaat gcgaacaggc gctgaagtgg catccttgac atcgctactt gcaatcacat
    63601 ttaataattg ggcgttttct ttaactgtcg gagcaaaagg tccaatctga tcaagtgaac
    63661 ttccaaaagc aatgagacca tagcgagaaa cagtgccata ggttggtttc aaaccgacaa
    63721 caccattaaa tgcagctggc tgccgaatag aaccaccagt gtctgaacca agagataaac
    63781 ggacttgtcc tgaagcgact gctgttgccg aaccacctga tgagcctcca ggtacttttg
    63841 tgtggtccca agcatttttc gttttcttga aataagaggt ttctgttgaa ccacccatgg
    63901 caaattcgtc catgttggtt tttccaatga caatcatgtc tttagcgtag gcatttgcta
    63961 ctgatgtggc atcaaaaatc ggctcgtagt tatacaacat ttttgaagcg gctgtggtta
    64021 ggatgccctt ggttgagata ttatccttaa cagctagtgg aatacccgac atgaggttat
    64081 cagcatcaat acctttggca tcgattgccg cagcttgtct aagagcagct tcttctgaaa
    64141 cagtgataaa cgacccgaca gcctcctcac gagacttgat atcttcaagt gttttttgag
    64201 tcaattcggt tgcggaaatc tccttagcta caaggaggtc atgcaactct tcaatggttt
    64261 tatgattaaa agacattagg catctcctcc gtcatccaaa atagcaggta ccttgataaa
    64321 gtgattttct ttttcaggaa catttttaaa gagcaaggca cggtctgttc cttcttcagc
    64381 gacatcttga cgcatcacat ttttcttatc tgccatggtt gttgtaatgg caacaccttc
    64441 ggtatcaact tcgttcagca attcaaccat gtcaacgatt ttagataggg tcgttgcaaa
    64501 ggttgttgtc tcactttctg aaaatgataa ttttgatagt ttcgcgacat ggcgaacttc
    64561 ttcttcagaa attttcatga tttctcccat ccaagatgac aagaagtatt ccagttccaa
    64621 agaacagctc tgctattctc taaaggtagc ggaaaaactt ctcacatcat ttttacatag
    64681 tctcaattat tatatcacaa ttgctcccat ttaccatagg tgactaatgc aattctagaa
    64741 agccatacag caaaaaactt cctgactaag gtcagaaaac cttagtcagg aagtgtgaca
    64801 aactaaactc tatttgtctt gggtaagact atggcctgaa gctttgatgg cagcctgagc
    64861 agccgccaag cgagtaagcg gcactctaaa tggcgaacaa gaaacgtagg ttaggccttg
    64921 gctgtggcaa aaggcaatgg aagcaggatc gccaccatgt tccccacaaa taccaagttt
    64981 caagtcaggc ttaaccgaac gggctaaaga gacggccaat ccctttctga tcaaaggtct
    65041 ggaacgggtc cttatcaaaa atacccctgt caacgtattc ttccaagcat tttcctacaa
    65101 catcacagaa aaagtaacgt tctttcaagt cggtaatatg tttacgaagg taataaaggg
    65161 gtgctttatc ctaatttacc aaatcctcaa cgattgtgac aacatgtgat gtgataagcc
    65221 taagataaaa atggtacagc ctctagcatt caagagtttg aagctttatt tatattctaa
    65281 tgctgaaaag actagagttt gtctaatggc tgtgagacga tcctctaaac catcaactca
    65341 aatcatttct caaacagcta aaatcctgtc ttcttcaaaa aaacatgtgt tctatctgac
    65401 acagtccaaa gtttagttgc cttttagaca gcacaagaat catcaggact aattctgacc
    65461 agcatgtcac atacctcatc tacctaaccc atacatacgg taaaaccaca tagagcaatg
    65521 attacggtta ccaaactctt agtcactgaa tcaatagttt ggtaggatct tttagtaatc
    65581 gttaataagc ttagcaccaa gaacctgctc aaagtgagcc aaagaccact cataagattc
    65641 ttttgtaagg ctagcgacag ccgatttaac aatctctaat tgataaccaa gatgataagc
    65701 gtcaatagca gtatgtaaga cacagatatc agataaaact cctgttaaca ctaattgagt
    65761 gatacctctt tctcgtagtc taatatctaa atcagtcccc gaaaaagctg aataataacg
    65821 cttatcaatc caaaaaactc tgggatgttg cttcatataa ctgtaaactt cagctagtgg
    65881 accataaaga tggcgtccag tagttccttt gatattatgt gctgcaaata gcttactctc
    65941 aggatgccaa gaatcatttt gatcatgaca atcaatagca aaaaaaatat agtctccttg
    66001 atcaaatgcc gttttagtta cctctgctat tttagtggca atagcctgag cagatttacc
    66061 tgcacttaat ttaccatcat ctgctacaaa atcatttgtg taatcaattg aaatcaatgc
    66121 tctcatcact atctcctaaa cagggaaacc tctcccctta tctcttatat atggcattgt
    66181 atcagttttt attacaggta tcaagacatc tatttgcatc taccattaac agcaaaaaac
    66241 atctcttttc aagagatgtt gtctttttct atttaaaatt cttttaattt agcaaaaata
    66301 ccttcgttga taactttgag gtatgtccct ttcataccaa gagaacgact ttcaataatc
    66361 cctgcacttt ctagtttacg cagagcattg acaataacag aacgggtaat accaatacga
    66421 tcagcaataa cagaagctgt caatcgtcct tcattaccat ctaactctcc aagaattgct
    66481 gcaacagctt tcatttctga ataagaaagc gtattaattg ccatgttgac cgctgtttgt
    66541 ttacggatgg tgtcttctaa gttttctgtc tgaagattta atagttgaat ccccacaaca
    66601 gtacttgaga tctcaaccaa aatcaaatca tcatcactaa actcattgtc attacgccag
    66661 ataatgagtg atccaaggcg catccctcca ccataaatcg gcgcaatagt cgttagacct
    66721 cctggataag tgtctttaga ctcaacaggg aatatagtca attcattttc gacagaaagg
    66781 ttagcttctg tatcgtaaac tcggctagca gcctttacat aagtatctgg aaattgttta
    66841 gcttcaaaaa attcctcaac acgatcagtg ttagttttat atttcatggc ataaccaagc
    66901 agtgtgccgc cgccattgat aatacaagca ttgcagtcaa tgatatctgc taggcgagat
    66961 gccattgtgt tatacggtaa ttctgtttct aggctatcta cggaacgctg caaaatagat
    67021 gtgattttac gagttttttc taataagtta ggcatttttt tccttttcct ttgaattatt
    67081 tgcgctttca ttataacaaa gctaactcgc ttttgcaagg aattatcaga aaattttcta
    67141 ttcttactac aattccaact attgatgcct tattatcact tcatttaaag gagataagca
    67201 ctagcttgtt agagcatagg gtcacattct tttaagaaac gttattttta ttaatcaaag
    67261 atgagcattg cattaacgtc tatactggta taagacacgt gtaatctttt cttgaacatc
    67321 ttctaattct tctacacttg gtaggtaaac aatacggaag tgatctggat ctttccagtt
    67381 aaaaccacgt ccatgtacca acatcacttt ttcttgcttt aataactgta agacaaattc
    67441 ttcatcatca tcaatacgat acatctgacg atcaattttc ggaaataaat aaagacctgc
    67501 ttcaggttta actgccgata agccagggat agcattaata gcttcataaa taaaattacg
    67561 ttgctcaaaa atacgccctc ctggcagtaa cagtgcatca actgattgat ggcctcctaa
    67621 ggaagtttga acaacttgtt gagctaaaac attggagcat aaccgcatat tggcaagcat
    67681 gttcaaccct tcaatgtaac ctttaacatg gtctttagga cctgataaga ccatccatcc
    67741 aacacgaaaa ccagcaatac gatgagattt ggaaaggcca ttcatagata cacaaaaaac
    67801 atcaggtgcc aaacttgcaa tagcaatatg ctctttacca tccatcacca aacgatcata
    67861 gatttcatcg gcaaaaataa tcagctggtg ttctcttgcc aaagcaacga tgtcttctaa
    67921 aatctcctta ggataaaggg ctcctgttgg gttattagga ttgatgacca caatagcttt
    67981 ggtgcgactc gtgatttttg atttgatatc agcaatatca ggataccaac cagcttcttc
    68041 atcacaaaga taatggactg cttttcctcc accaagactc acacaagccg tccataaagg
    68101 ataatccggc attggtacta aaacttcatc gccattatct agcaaagctt gaagggacat
    68161 ggatatcaac tctgacacgc catttcccaa ataaatatct tcaatgtcaa catctgggaa
    68221 gcccttgagt tggcaatact gcatgatagc cttacgtgct gaaaaaatcc ctttactgtc
    68281 agaatagccc tcacttagcc tcgcgttgac aattaaatca cgaatcactt catctggtgc
    68341 ttcaaaacca aaggcagcag gattgccagt atttaaacgc agaatttttt caccactcgc
    68401 aatcatgcga ttagcttcat ccaaaacagg ccctcgaata tcataggcaa catgttctaa
    68461 ttttgatgat ttttcaataa ttttcatagt ctcatacacc tcgtattcca tattataaac
    68521 caaaatactt aaaatagaaa gaatttatcc atcaaagctc aggacagcta atcgttttaa
    68581 cacaggtctt atgagacgat aatacagtct ttagtttagc taaaataatg gatcgctttc
    68641 aaaatgactc aaaaaagagt ataatgaaaa aaagaataaa agctattctt gtcaaactgt
    68701 taaaggagga cagttctatg tcactaaaat ataaacgtat cctcgttgct attgatggct
    68761 cttatgagtc tgaattagct ttcaataaag gcgttaacgt agcactacgt aacgacgcta
    68821 ccttactact agtacacgtt attgacaccc gtgccttgca aagcgtagct acttttgata
    68881 cttacatcta tgaaaaatta gaacaagaag ctaaggacgt tttagatgat tttgaaaaac
    68941 aagcacagat agcaggaatt acaaacacca aacaaattat tgaatttggc aatcccaaaa
    69001 acttactagc tcacgacatt ccagatcgtg agaacgctga tttaattatg gtaggagcta
    69061 ctggtcttaa tacctttgaa cgcctcctta ttggctcatc ttctgagtac attatgcgac
    69121 acgctaagat tgacttactt gtagtccgag atagcactaa aacactctag tctattacaa
    69181 ttttcaaaaa ccaaaaaaca agcagcatct acaacgaaat tgcttgtttt tttgtgctga
    69241 gctaagtcta gtcaatatct ttttatttct tgatatttaa aagagtaaac ctctatttat
    69301 cgaatcgttg tagtgatttt tgtaattgtt tgtctaactc tttttttatg gctacttcag
    69361 gtgcgtgacg ctcttgccaa tagtcaggtt tttgaatttt atgggtaacg gggtcaaagt
    69421 gtgccttgcc atctggaaaa attttagcca tatttgcttc atgtactgct tcaaatatag
    69481 gttgtggatc tactcccatc agtacaaaag aaccataagt aaaataaagc aaatccgcta
    69541 aggcatcaac ttgcccaatc aggggcgttt caacatgttt tttagcttgt accttattag
    69601 ctgcttggtc aacagcacca tgcaaatcga aaatagcctg tgtaaattgt tgttggtctc
    69661 ccttgcttgc tgcgtaaaga aactcaacaa tttcttctac tttaaagcct gacctataac
    69721 cagcttctga aatggtataa ctacgcggtg tttcaatagt atctgagtcc atcagacgat
    69781 gaaaatcttt gactttatta aaattttcat cacggctttt aaagctcttc tctatatcaa
    69841 aatggatgag accgtagtga gctaaggctt tggaaatccc atcattatta ttagagtcgg
    69901 tagtgaaatg ggctccatct tttaccacag tttcagcatt tcccatagca ataccgatac
    69961 caactcctga taacatttca aggtcattat ctgaatctcc aaaagccatc acttcagaca
    70021 agtcaaatcc aaacatctct cccaaacgtt caattccttt tatttttgat tgatcaacag
    70081 agatcagatc caaggaataa ggactacttc ttgtaatttt tatatgaggg aacttctctt
    70141 gtattttctt agtttcagct tgtgacgcta ccagaacaac ctgataaata ggctcccgca
    70201 taatagttac taaatttcta aaactctgag gcttgattcg gcgaatcaaa tgcttaaaac
    70261 taccctcaac tgttcttgcc caacttttgg gcacaaaact actaatgact tgtccaaatg
    70321 ggctagtccc catatcaata atacgcgatc ctgctaatcc agaagctgtt ccaagagaaa
    70381 tttctcgctt tttttcgttg gcatagcgaa tcactttgta aatcatcgac tttggcaatt
    70441 gattctgata taagacctta tctcttgtta agatatattg cccattgtaa gtaacggcaa
    70501 aatctaatcc aaaattttct agaaaaggtt gtacaaatcc cggtccacga ccagttgcta
    70561 aaccgaccat aatgccttgt tttttgagtt gttggatggc tttttgcgtt gttttttgga
    70621 tatttttacg atcattgaga agggtcccat caatatcaaa aaagactgct tttactgtca
    70681 aaaccttctt ttgcctcctg tgtttatgat agaatagatt atatcataaa taaaaggaag
    70741 tttgacaatc aaatgaaaaa aatcctagtc ttacacactg gtggaaccat ttctatgcaa
    70801 gctgataact ctggtagggt tgttccaaat caagataatc ctatgacgaa aatacatgct
    70861 gcagcccaaa atattcagct taccgttagt gattttctaa atcttccgag tcctcacatc
    70921 acgcctcacc acatgttatc tatttatcat catattcaag aaagaactga tgtttttgat
    70981 ggtatagtca tcacacatgg aacagatacc ttagaagaaa ctgcttattt tttagatacc
    71041 atggcattgc ctactaatat acctgttgtc ctaacaggtg ctatgaggtc ttctaatgaa
    71101 gttggtagtg atggcatata taattacctt accgcactta gagttgcaag tagtgataaa
    71161 gctaaagaaa aaggggtact tgttgttatg aacgatgaaa tccatgctgc taaatatgtt
    71221 actaaaacac atacaaccaa tatttcaact ttccaaacac ccacacacgg accgcttggt
    71281 atcatcatga aaaatgacct actttttttc aaaactgctg aacctcgtat tcgttttgac
    71341 ttgagatgca tttctggaac catccccatt atcaaagcat acgcaggtat gggcgatggt
    71401 agtatcttga gtctattaac tccaggtagc attcaaggtc tagttatcga agctctaggg
    71461 gcaggaaatg tcccaccatt agcagttggg gagatcgagc acttaattac tttaggtatt
    71521 cctatcgttc ttgtttcccg ttgtttcaat ggtatggcag aacctgtcta tgcttatgaa
    71581 ggtggtggtg cgatgctaca agaagcaggt gttatgtttg taaaagaatt gaatgctcca
    71641 aaagcccgtc taaagttatt aattgctctc aacgccggac ttactggtca agagctaaaa
    71701 gattatattg aaggataatc tagcttcctg tagaaatgtc ccactaaaac atattagtgg
    71761 gacatttcta gtactttaag ctttaaatta ggacatctcc taaatgtcta taataaacaa
    71821 ctatgtttca aactatgaga ttgtgcactc ataatcattt ctataacagt ttgagaccag
    71881 tattccaata aatccaactc ttagcaatca gataccgggt aaacaagtct ttattttgtc
    71941 tcattaagta tgagcttact tgaataataa caaaactact tgctcatcct tttttagtaa
    72001 tgatgaagac gacctttttc taagaacttc tttgtctttt aaaataaaca aagcacatat
    72061 taccctttat tttagttctc gtttggaaaa aagaaagaca ttgcctaaaa gataacaaag
    72121 agttaaacca aaggccacta atatgctagt actagaaaga tgtttatcac caagagacaa
    72181 ggataggtgt ttaaacatca aaactgggct aatatctaac ttaaaaaaat ggtttgctaa
    72241 agtagcagat actttatcaa aaagaaggac ataaagtata taagctgtga ttgactgata
    72301 agttttacga agtatattaa acaaaaattg acacaaagca ataatagcaa tataaaaagg
    72361 cagttgttta atcatccgat ctatgactat tccatagtat gcttgaccag taaataaatg
    72421 aaatgctaaa gcactaagaa gataagttaa actaataaat aaaagagata agccaaaact
    72481 aactagcagt ttatagatta taattaaagt acgattttgt tgtttgacca caacattatt
    72541 aatcgtacgg tagttatagt catcactaaa aaagatacgg gctggtgtta aaaagaaaag
    72601 cgtcacaaaa tcagtaataa tattaatgat ttgtatcatg atgacttggt taggtgtctt
    72661 gcgaaaacta taggctacac caacagcaat gacaacaagt agcatacaag aaaatagagc
    72721 taaacgctct tggcgtatcc gaaataaatc tgctttaaga taggaaatca taaaaacctc
    72781 tttctaaatt aatggtgatg ctgcatcttt acctaacaaa tcgaggtaat aatgttcaaa
    72841 gctcacttga tgatgataaa tgtcaaaaat ctcaacaggc agatctagaa caattttgat
    72901 aagctccatt actgataaag ttggttttat tagtagcatc tgaccatcag tctcaactct
    72961 aagccccaat tctaaaagtc tattttttac cagctgatca tcgcttgtat gaagggcaat
    73021 ttgtactttt acttgagctt taagctctgc tttgtccata ctcttaataa ctttgccttt
    73081 atgcataatc acgtaacgat caacaactaa gtctaattct gataaaatat gactggaaat
    73141 caaaatcgta ataccatagc aatctcttag gttcaaaata atctgacgca tttctttgat
    73201 tcctgctgga tcaagaccat taatgggttc atctaagatt aaaaattctg gaaaatctag
    73261 tatcgaaaga ccaacagcca aacgttggcg catccccaaa gaataatctt tcaccttttt
    73321 ctttttgctc actttttcta acccaataag ttccaaaacc tcatgtatgc gctctttcgc
    73381 atcagctaat ctcaattgca acgctgcata gtaaagatta tcatgagctg tcatattggg
    73441 ataaagtgtc ggtgactcaa taattgatcc cattcgatag ggttgtaact gtttgatttg
    73501 ccctgaatct tttccaatta ggccagataa aatacgcatt aacgttgtct ttccagcacc
    73561 attttgaccc acaaggccgc aaatttctcc tttgtaaata tcaaaagaga tatcacttaa
    73621 aacctgattt ttaccatagg atttatttac ttgctcaata cttagtaaca ttgattgctg
    73681 tgtcattttc cgctcctttt ttgtacttat cgattaatac aatatcttac acataataac
    73741 atctgtaaac ggttgtgaca agttcttctt tttattaaaa aaatataaat aagaatttta
    73801 ataatatgat tattttagca ataaaaagtt atactgaaaa tgggttaatg ctgcttcaaa
    73861 tagcagtctc atcgtaaagc ataagtaaaa aaggccagaa atagtgacct ctttatactt
    73921 tataacagtt tatctcaaaa ctaactaaat atttgtaaaa caacgacttg ttttaagtta
    73981 atcataaact tctttttttc taatattttt tgctactaat tgccactgtt tttcatatat
    74041 ccagttagga tcagaaacaa tcgctgcaga aactttgcgt gcttcttcta aaataggata
    74101 atcctcaacg atatcagcta cttgaaactc tggaattcca gactgacgag taccaaagat
    74161 ttcaccagaa ccacgcattt ttaaatccga ctcagccaaa acgaaaccat ctgtcgtttc
    74221 tgtcatgatt gtcattcgtt ttttccccga atccgttttg ggattagcca ctaaaacagc
    74281 gtatgattgt ttatgtccac gaccaacacg cccacgaagt tgatgtaact ggcttaatcc
    74341 aaaacgatcg gcatccataa taatcatgat cgttgcattt gggacattta cccctacttc
    74401 aataactgtt gtggatacta aaatatgact ttttttatcc ttgaaatctt gcattatggc
    74461 atctttttca tcatttttca tacgtccatg tacaagagca accttagcaa ttccttcaaa
    74521 ataagtagat aattcagcat gcaatgctac tgcattcttt aaatctaaag cttctgattc
    74581 ttcaatcaac ggtgaaatga catacacttg agcatctttt tgcaattcac cttttaccca
    74641 ttccaacaca gtccctagct gctcgtgttt cacccagcgt gtcataatag gtttacgacc
    74701 ggcaggtaat tcatcaataa cagaaacatc catttctcca aaagctgtga ttgctagagt
    74761 tcggggaatt ggggtggctg tcatcattaa aacatcagga ttttctccct tttcacggaa
    74821 aattctacgc tgtttaacac caaaacgatg ttgctcgtct gtaatgacaa gccccagttt
    74881 atggtactgt accgagtctt ggataagagc atgagttcct acaatcatat caaccgagcc
    74941 atttgcaata gctgctaaaa ccgtacgctt gacagcggct ttcatacccg aagttaatat
    75001 agcaattgat aaatctggaa ataactcttg cagactaata tagtgttgtt cagctaggat
    75061 ttccgttgga accatcaaag ccgattgaaa acctgctgta taagctgcat acattgatag
    75121 actagcaatg actgtctttc ctgatcctac atctccttgc aataaacgat tcatatgagc
    75181 tcccgatgac atatcagata atatgtcatc taaagagcgc ttttgagcat ttgttagaat
    75241 aaagggtaaa gaggaaatct ttgtctccat agcatgttta ctataaagaa taggcaaacc
    75301 atttgtttca gatctatttt cggctttcaa aacttgaagg ttcatttgaa agtaaaataa
    75361 ttcttcaaat ttaatccgac ggagcgcttg cttatactct gtgatatctt ttgggaaatg
    75421 catagctaaa caagcctgac tacgacccat caatcggtat ttttccaata aagtagctgg
    75481 taaattttcc ttcaattcca aatgcgcatc gatttcaaaa gctgacttaa tagctttaat
    75541 caaagtagac tgtgaaattc cctgagctac gcgataaaca ggttgcatgt catcttcaac
    75601 ttgagctaaa accttcatcc cagtaatagc cgatttagtg gcatcccatt taccaaaaac
    75661 agctacctct tgaccaagtt ctattttatc agctaaatag ggttgattaa aaaaactaac
    75721 atttaagaca gcttcccctt gacgcaattt gaaacttaaa cggttacgtt taaaaccata
    75781 atattgtaca ttagctggag taacgactaa gcctgtaatg actgcttttt caccatccac
    75841 taaatcaaaa acagattttg atttaaaatc ttcatagcga aacggataat aaagcagtaa
    75901 atcttctact gtataaatat ctaatttctg aaatttttct gctgattttg gtccaaatcc
    75961 ctttaagttg gacataggag ctgttaatat cattatcttt ttcccttcac aaaaactctt
    76021 gtcagattga agacaaagtt tgtcgtgata ctttccttag gtggtgctta cggcagcgac
    76081 gttctttgga attccatgcc tttatttttg agcctgaggt ctcaaaaatc ccgagtggcg
    76141 tcaatctcgt attgacgcca ctcttttacc acagcaaaaa gcatctgttt tggctcactt
    76201 tatatgtaaa aatcggaaac cgaatgtcaa atcagcagag ctatgcatgc tttttgagca
    76261 taaaactgga gttgtctacg ttctgactct tgtatctatt atacaagagt tcctatttat
    76321 tttcagataa aagcctttta gtacttttaa acagttctag gagctcgtta aggtagcatt
    76381 tgataaatgg tatcgcagac actacttaga agttcttcat catgtgaaat gaggatgaca
    76441 accttatgtt gggtcttcag ctgcatgaga agattagcta aagccttcat ttgtaacaaa
    76501 tcaagtccgc tacttggctc atcaaaaatt aagatatctt tatcagccaa aagactagcg
    76561 gcaatcatca ctctttgttg ctcacctcct gacaaactag ctggatgacg ttctaaaaga
    76621 gtcgttaaag ataaccgctc tattacttct gtcgtccgtg gatgtcgttc atggcccaag
    76681 ttgacttcct ttgagaccga ttctgcaaat agttgcaaag aaacttcttg caagacaata
    76741 ctagtctttg ataaacgttg cttggcagat aaaggtatgc cttgaaactt aatagttgct
    76801 tttttatcgt ctaagatacc agctatataa taaactaatt gcgattttcc aagcccgttt
    76861 gatcctgtaa tgccagaaat acttcctgca gcaaaactaa gctgttcaat acatctaagt
    76921 attttgcttc ccgctctaac tgttagatgc tcaatacaca ggctatcatc tgggcgataa
    76981 tgttgactct caatcttacc agctaacaca ggttttaggt cagacaagtc taagcgacgt
    77041 agtcccatat cttgccgttg ttcatctgtc aaggctagca aattttgtgt tgttaactta
    77101 tctgttaatc taccattttt aaagtagaaa aagttatctg ccaaatccat caagtaatgt
    77161 aagcgatgct cggctacaat aatggttttt cctgctgctt ttaattgggt aagataggct
    77221 ttaatagcag ctatgcctgc actatctaag ttagcagttg gctcatcaaa aagcataata
    77281 ttagtacctt gcataatggc cgttgcaata gcaactcttt gtttttgccc tcctgacaat
    77341 ccaaacatat ccttgttaag gagctctgca aaagcaaaat cttctgctaa agtccaaaga
    77401 cgcttcatga taacctttgc atctagacct tgattttcac agggaaagac cagttcgtgt
    77461 tggacttcgc gatagaaaaa ctgactggct ggattttgaa aaacagaggc cacagatcta
    77521 gaaaatgttt caacactgtc tctgcctgct tggcaatcag ccacatctag tctaccttca
    77581 tattttccag cataataatc aggaattatg ccattaagaa gttttaaaaa ggtagattta
    77641 cctgaaccag aaggtccaca caaaacaatg aattgtccag aggcaatttg acaagtcggt
    77701 acctgacaag ctggattttt ttgatcatga taggtaaaaa caagttgttc tgctgaaatc
    77761 attgaagtat cgtgatgatt atgataacag taatccaaat ctgcaccccc caatctttcc
    77821 atgttaagtg tgagctaaag cattcactgg tgcctttgtt gactgctagc cctttagtta
    77881 gactagcgat agttagttct tggctacttc ttatcaaaga taaaagcaat ggaaccatta
    77941 aatactccaa gtattgttta ggtctgatca aaatagacca ttttgttaaa ataatccccc
    78001 tgattgttaa agagcgatga ataacacaac attcttgtct aatcattggt atgaaacggc
    78061 acataacggc taaggtcaat agccagactt ctgggaaatg ccatttgcgt aatccatgaa
    78121 ccaattcgta gatggtagtt gtcttaatag taattaaacc tgctagtaaa gaagggaaaa
    78181 ctaaccttcc tgctattgag acaaaactca ataagtgatc aagataagaa gggaaaatcg
    78241 atagcgggat tacagataga ccgatcatta acagataaac aaccgccaac ttgaacgcta
    78301 gctttttctt atttaaagca gacaaaagta ataagagaaa aataacaatt ataaattcta
    78361 aaaagccatc aacacgaaaa aagaagcagg cattggcaag taccaacaaa agcagtttgg
    78421 tgcgaacatc aagcctcatg ataacaatcc tgatttgata aaatgtttct ttagtaaata
    78481 atgtgcaaaa gctgacccta ataaggctcc tgcaagaaca attcctacaa accaaataac
    78541 atgccctaaa ctaaaatcat acataatgcg attgacatag gtcatacttt taccgcgggc
    78601 taacaaactt tcaacatagg catctttcaa caaccacatc agcaaaatag ggccactatt
    78661 gacaaaagca aaaaccatat aagataggtc attaaaaaac cttgacttgt attttcctaa
    78721 agaagcaata atatccgcta ttaaaccgaa aataatgctg ggaaacatcg cggcaaaaaa
    78781 gtgaccacta aggaagaaaa aacctcccat catcagtcct aataatgtta ttggcccaaa
    78841 tgtttgcaat ttagcaatca aaagaaaata aattgttccc cccagtaaag ctgcaaaggc
    78901 aggggcatat aacatatttc ctgagcgatc aaaaaagatg ttaataaacg tgcctagacc
    78961 aacacaaata aagtagagcg cggcaaatgc gcctgttatc ataatatctt ttattgttaa
    79021 ctgtttcatt ttttattcac ctcttttagg aaaccatttt ttacgcaaaa tagatgatca
    79081 gcacaagcta gggttgatgg cctgtgagaa attaagaaga ccaatccttg acaatgtgtt
    79141 ttaattaaat caagcaagat agcttcattt agagaatcta aatttgacgt gggttcatca
    79201 aaaatatagc aactcgcatc tttcaataaa gctcgcatca actctaaacg ttgaccttct
    79261 ccagctgaaa agtcagaagg actcttgata atcgtatcca aaccttcctt acaagctaac
    79321 agtctgtctt tcataccaca agcctcagct aaattccaaa tggactcatc tgaaatatct
    79381 tgacggccaa aggtaagatt ttcacggata gactgttgga aaagctgcgc tgtttgtggc
    79441 acataagcaa tagtatcttg taatttagca gcatttagta agcaactatt cctatcatta
    79501 agaaaaatat ctcctgtctt ccaattatac catttcataa ttaatttcac caaagttgat
    79561 ttaccagatc ctgattcgcc tttaatgcca ataatcccct tttcttgaaa ggtaactgtt
    79621 aaatccttaa aaaccagctc ttggcgcttt ggataagcaa aactgaggtc ctcaaaagaa
    79681 acactcctta aacgatctat ttgttttgtg ccttcatcta ctatgacatt ttcgtctaga
    79741 aggtcaaaaa tatttcgagc cgcattcata gcacgcttaa aacctaatgg caaacgtcct
    79801 agttctaaaa aaggagaaaa cgaagcagtg aaagcaataa aagttaataa gcctttatca
    79861 aatgataagc tgtcatggca tatcccatca aaaaccatat aagaaaatgc taagatcatt
    79921 aagccaagcc agaaaaaagt caatgccatt tgcaaaaatt gggcttgcgc tacgttacga
    79981 tcaagagcat ttacatgatt actttttttt attaatcgtt caaattgctc gtctaatacc
    80041 tgaaattgca aaagatcttt gactgatcgt aaactctcta aaaaataaga caggtaatct
    80101 tttcgacctt cattttggct ttttagtaaa acctgtaaaa tattagcaaa ataaatgggt
    80161 ataacaatgg ctaaacaagc ataggttgcc aaagctaata aggctaactg ccaactactt
    80221 tgacaaaagt accagaacat taaacctgca gacaatattg ctgtacaaat aggtgcgatt
    80281 gtgtgggcaa aaaaaacttc taatgcctca atatcttctc caatcatttt aagcaaataa
    80341 ccactgtctt gactatccaa gcaagctgga gaaagagctc ttagtttctt aaagatcaag
    80401 ttcctaaaag ctgctaaact atgaaaagca acaaaatgac caaaataatg ctctccataa
    80461 cgaacaaaac ctcttaaaaa ggctagagca atcaaaagat ataaagctaa tattggaatc
    80521 acttcttgtc taatagctag tagtcctaaa taagctattc cagttggaat acttaccgtg
    80581 atgacaaaac ccataacagc aaagccaaca gccaagataa tccaaggtag aagagttttc
    80641 attagggtta ataaacgcca aaccaggctt aaggtagatc tgttaggttt agccataaat
    80701 acttgcctcc agtcttgctt gagtatcaac taggtgacga taagttggtt ggtcccgata
    80761 aaggtcgcaa ggtttgccta aacaagcagg ctgccctgtg tttaaaaaga gtacttggtt
    80821 agctcctttc agtcgagaca tcttatgagt aatcacaata actattgctg tcttagctaa
    80881 tctcgttatt aaattgtcaa taatacgttc attttctgca tctagactag atgttgcctc
    80941 atcaaagata taaagagacc tcttacttaa tagagctctt gcgcaaatca cctgttgctt
    81001 ttggcctggt gataacaggt taccattttc accaactatt gtgtcaagac catctggtag
    81061 ccagttgatg aagcttaaca aaccatgttg atctatccaa tctaagattt cttttttaga
    81121 gagatttgct gctaacctta aattatcgta aatgctacgg ttcaataagg tagattggtc
    81181 cgatacataa agaacctgct ggttgatagt ttcttgcgac aaattgtcac tgtctaaacc
    81241 gtcaaataaa atatgcccag tcgttgcaga ctggcgtttc aagaggagtt gagctagact
    81301 tgtttttcct tgtcctgaca cccccgcgat agctgttagt tggcccttcg ttaatgtcat
    81361 ggtaacccca ctaagcactg tttttttctc ataagctaaa gaaatatttt ggatgtcaat
    81421 ctggttaaag tttattgctg ttttactctt gttatctttc cttgctggaa cactatccaa
    81481 gaaactaaag atacggtcag ccattttggt attcatcatg accaagtgca tgccataacc
    81541 ctgctcacga atcggtgtaa aaaattctgt agcaatcaag agaaaaaaga ggaaattaaa
    81601 aaaagataac tggcctgttg ccaaagcttg aacggctaaa aaacctgaca aaccaatccc
    81661 cagatacata actgcatcca tataaccaac tgcttgtaac tgaaagccaa gcaaagacat
    81721 ggtagccttt cgaaactgtt ctgccttacc cgaaaattct tgctcgtaac gtcctgttgc
    81781 ttgataagaa tacagtgtat taagaccttt taagtcatcc ataaataaat taccaacatc
    81841 catataagaa gaccaataat gactcataat ttgcttagac cgcttttgca tagcaacaat
    81901 tgaaagtgga atcagaggca gaactcctaa aaagacaagg cctgccaatg gataaattaa
    81961 aaagactagt atcataatag ttgtgcagtt ccacttggtt ctcatagaca aagacaaata
    82021 gtaaccataa taagtatcca aactatcaat cccctgtgaa gccaacgtta aaatatcagc
    82081 atcactggca tgagcatcaa attgcccgtc taaatcaata aaagcctcaa agaaagattg
    82141 tttgagtgaa tctctagcaa attgtgaagc gatcccttgc agttgcttgc ctaatatagc
    82201 aagaacaaag cctaccacat ttaaaagtag gagtaaacct gccaagcgtc ctaaggcaat
    82261 agcatgaccc aaaataaagg tcgaaaacgt tttggcaatg aggtaaaaac tgatcatcct
    82321 catcacaaat tgtaaccaag ataaaaaggc tgacacataa agcaaatacc tttttggtgc
    82381 aattcgttca cgtaatcgtt ttaacagtct tttccttttt ccccttgata ttgtatcttc
    82441 tgtttccatc atctgttctt gttcctatct ctcctttgag ttctaatatc attggtttca
    82501 ttgaccaatg aagtgaggac aaactgttga ccatttctct caacaaaggg caattcaaca
    82561 ccaaagacat ctctgataaa ctgttgatca aggaggtctc ttggttgccc ttgggcataa
    82621 agtcgcccat ttttcaggcc aataagatgg tctgaaagag acaaagcctg attgatgtca
    82681 tgtaatacta acacaatcgt taggcctagc tcttggttga ttttagtaat cagcgtgaga
    82741 atgtcaagct ggtacttaat atccaaataa gtcgttggct catctaaaaa aataatatct
    82801 gtatcctggg caagggccat ggcaatccaa accctctgct gttcaccacc agaaaggtgt
    82861 tggatgtcac gataaacata atcactcaaa gccgttactt ctaaggccca agcaaggtgt
    82921 tcctcatctt ctttggtagt agttttaaaa aaagaacgac gggcaagcct agccatggct
    82981 accaattcac ccactaacaa accttcgacc acttgatggt attggtgtac cactgccact
    83041 tttttcgcaa aagccttgag agaaatcgtt gctaattctt cctgctcaag ccaaacctgc
    83101 ccttgtttta acggaaggtt tttggttaat aattgtaata aggttgactt gccactgcca
    83161 tttgccccca taatagtggt aattttccct tttggaatgc taaaggtcag gtcatctaaa
    83221 acaagttttt cctcataagc aaaggaaagg ttttgcacct gaatatgact gctgttctta
    83281 ctcatataat atcagacctc cttagcaggt aaataaagta aggcccgcct acaatactca
    83341 ttataatcgc agggctaatt tccaatgggt aagcaagact tcttcctaaa gtatcggcta
    83401 gcaaaaagac aaaggctcca agcaaagctg aaaaaggaat taagatttgg tgcttacttc
    83461 caaccagcaa gcggctcata tgagggacaa tcaagcctag gaaagaaacc actccaacga
    83521 tcgaagtggc taccgaagcc aataaaacag caaccaagga aattcccaac cgtaacgctg
    83581 tagcatcgat tcctaaatga cgaatcacct gatcatctaa aagaagaagg ttacaggttt
    83641 ttgacaataa caaagctagt aacaagccaa tgaatgtata agggaataaa acccctacat
    83701 cagcccatgt tttttgacta atatgacctg ctaaaagagc attgaccatg ggactagctg
    83761 aggtgaaaaa gctggttaaa gcagttgata accccataaa taaagcatta atagcaatcc
    83821 ctgttagaat aagccgaata ggattaagcc ctttcttcca tgctaaacca taaatcagca
    83881 ggaaagacac tccgcctcct aaaaaggata cgattggacc atacagcagc aactgcggca
    83941 gaagtaaact agagactaaa accataaaac tagcaccact acaaatccct ataatagcag
    84001 ggtctgaaat aggatttttc aacactgctt gaaaaagaac tcccgaaaca gctatccctg
    84061 ctcctgctaa taaagcaatg acaattcttg gaaagcgcaa atcataaatc aaagccactt
    84121 gggggtcata agccacaaac agtcccttga caattgcccc ataagaaacc gccaaaccac
    84181 caagggataa ggcaataacc gccaaaaaca ggaggctgag aattaaaaga actagataaa
    84241 gaccacttct gaaacgtttt ttagccagta gggattgatc cctttgtaaa tctgatgctg
    84301 tcatgttacg gatgatctcc cacgcggtca aaaagctgtg ttaaggtgtc caaggcttct
    84361 gggtagttca atttagcact catgccaaac agggtattgt ccaaatcata gactttccct
    84421 tccttgactg ccgtaaaatg tttccaaata tcattttcag caaattcttt gtcaaacatc
    84481 acttttacct tgtctggaat ggcatgagct gttcgtaaaa tcaagtcagg ctccttagcc
    84541 agcatgtctt caggattagc tgatagaaat tctttctcat ctgactgata aacattctca
    84601 ccacctgcca agtccaaaag attccctaca taagattggt tcgtcgccac caaataacta
    84661 cctggcaagc ccataagaat aagcacttta ggctttttct tccccttacg tttagcttgg
    84721 aaagcacgat aatagtcctg gtattgctgg cgcaattctt ttgcttcttg ttgacgttgg
    84781 aaaaggttcc ctaaatcatc aatggactgg tacatgccct caacactccg taagttcaaa
    84841 aaaccatact cagtatccaa tttttgatac ttgggttcca aatcttcttg taaagaattg
    84901 ggactcaaaa tccaagttgg tttcaaagaa gcaatcagct ctatatcagg attcatgggt
    84961 aaacccacac gcttaacagc atcatagcgt ttaggaaggg tatataattt actatcacaa
    85021 accccaacga ggtctaaatt taaacggtca cagatatcaa ccacagcaac cgaagtggct
    85081 acaattctct gctgttcagt ctctttagcc gttttagggt gctgattcac acaagctacc
    85141 aaaaagaagg ccattaagac tagaccaatt cctttacatc gttttatcat ttttttcctc
    85201 tttttccaaa cccatacagc aaaccctcct aacatcagaa aaaaagttgg aaagtagtag
    85261 atcatgattg ataagtcttt tttagaccga aacttatctt ctttttttaa ctctaaagaa
    85321 gtcgttaagc ccatcttaga aggaagaatt tttttatctg atagactctt gttatttgat
    85381 gagttggctt taggcttatt ctgagttatc atagcacctg tgtgagactc atcttgactt
    85441 tctcctagtt ttgtatcaac aggcttttga ctgtctttta cttcttgatt ttgagaattg
    85501 tctgtttcag taacaagctg ggccaacata ttacctgaat acttttgtat taactctgaa
    85561 gctgacaggt aaaagaccac ttctctgccc ataggttcaa caaacatgct tcctcgaatg
    85621 atactattta cagtaggcaa actaatagca atatctagtg ttgtcccatt ggtatcagta
    85681 cctttttggg tgatattgta atcaactgcc tgaaagcttc cagttcctcc aggttgtatc
    85741 cagaactgat aattacccga ataatcagct aagctcatac gaaaagtaag aacgatcttt
    85801 ccagcatcag atacttctag catggcatca ctatagacag tcccttcaac cataccttga
    85861 ccaatatcaa aggaatgctc ccctccacta tcttctatct gcccagatat cgggtgacga
    85921 taatttcttt gaataataca tccataaatt tgacctttat ctgcatacac aagatttgtc
    85981 attgttgata aacttatcat gaacactact attccctgca acaattgctt tattactacc
    86041 tttgtcatat gctcctcttg tctatctttt cttaaacatc ttatttcatt ttttaaatga
    86101 ttcccatttt ataacatctc caaatgtgaa aaacacacct atcttgcgac tacttcaacc
    86161 tgtatcagga atcctgtcgg aaataggtat gtttttagct cttgctgact agcttttttg
    86221 ttatttcact tggtactaag tttcttattt aaataatgtc tttcgaccaa taatgaatcc
    86281 cagagctacg atcataaagc tagatagacc tgcaattaag tgataacgag agctactttc
    86341 ttcaccattt gattgttgat tggaacgatg tttcttatca gattttttag tcttagtatc
    86401 ttttgccgtt ttaccttcaa ttgatgtttg atggtcacgc actaactgct tcaatttctc
    86461 tgccttatca gtatcatctg tcttagaagt ttcttgagtt gattggccgg ttgctttttt
    86521 agccaggaga tcagttaagt tagcaatacc agtagctgct gaaggaggac ttgtaggtgt
    86581 tttttcttgt tgacgatttt gaggtccttt caactgatct gttgaagtta gatggctatt
    86641 ttcttgtgga ttattagttt ctttgacaac ctttgccttc tctgttgtaa ggcttgccca
    86701 gtctaaacgc ataaaaacgg tttgaaggcc agaccctttt gaaatggcat ccatgatagg
    86761 cacaaagacc tgtaatggca caagtccgtc tttcttcgct tgttcaatca atttcatacg
    86821 cagaactttt ggatagtttt ttccataacg atctgccaat ggtaggccag ttacatccgt
    86881 gaaataagac acaacctctg ccttttttgt tcgaccaact agtttaccag ctaaatctct
    86941 ttggtaacca tctacgaaat agctcaattc accaaggtag cctaacattt taccaacctt
    87001 tatccctcta aactcaacct ctaaataggg aacacctttt ttaactacca aagtcacccg
    87061 atgattaata gccttgtttg acatggactc agatgctaag tcagttttta acatgctggc
    87121 atttaaatag taaataccat cacgcaattg tttttgattt aatgctctaa ggccgttctc
    87181 aactaaatct ttctgatgtg aatgtggtcc tttcgccaca aggatatcat tagatgtcaa
    87241 atagatatgt tctttttgag tagcaaattt ctttgttatt aaagctttgc gaatccgata
    87301 tgtacctgga tcttttaaag aaaactctcc cgttaagtca tctttcggat catttgagag
    87361 aagcttttcg ttaaccgtca catactgtcc attggaagct tttttttgca actgaatcac
    87421 aatactccaa tcgacttgca tatcattaag taaagaaacc gtatctgaac ctttttcttg
    87481 taacaattgt tgatattctt caatagacac tagttcttta tcaatggcag aatttgtttt
    87541 ttgctcccaa taatacaaat ctaaaagact gaaagcttga tgatatttta ttttttcgcc
    87601 atctaaagaa gcttcaagtt ttgcaatatg tttttgtgga gtcagtttgt gttgtccgat
    87661 aagagctctt acttttggac tcacactttt tatctgattg aacttcacat ctaaattaag
    87721 cgtttcaaca tctggaaata ctgattcttc aacctgagta agcaagttat tgaaaaaatc
    87781 aagttttgtt aattggttat tctgtttaaa tataccattt ggaagatttg aaatttcatt
    87841 agttgataaa tcgagtacag ataatttagg aagattttta aatgaaatat tatcaatacg
    87901 agtaatatga tttctacttg ccacaatagt gcttaaggcg cgcaattttt ctattgtttt
    87961 tggcagtagt gctaaattat tttgagataa gtcgataaag ttaagtgatg ttagaggctc
    88021 tagcgctttt tcaggtatct cctcaagact attttctgcg aaacctaatg aagtcaggcg
    88081 agacaatcct tcaaatgggt tatcacaaag tcggccaata cgattcttgg aaagatcaag
    88141 ttgctccagg tgatgaagcg actggaatag tcctccttca agagagtgaa taaagttact
    88201 tgataagtag agttctctta attgagcatt gcttttaaat gtatctttgt ctagataagt
    88261 taaatgatta cttcttaagt taagaaatcg aagttgcttc atttgactaa ataactcttt
    88321 tggaatttcc gtaatttggt ttccatccag atgtagttct gtaatatttt tagcatgttt
    88381 caataaagaa atatcagtta actcgtaatg gtctagacgc aactcgcctc gaatctgttc
    88441 taattccgtt tttgataatt taccatcgcc gtctaaatct ttgccaagtt taactaaaac
    88501 tttttcaaga cgttcagtcc caaccccttt ttctttatca tcagtttcta cctgataacc
    88561 actccagcct ttggtaacgg tcttactaaa ggtcatgtca agtttggtgt atttgtcata
    88621 gtggtttaaa tcactttctt gacctcccat ggctgatacc aaaacagcac ctttgtgtaa
    88681 tttatccaaa tcatcaatag gcatggtaaa ttcgcttcga atatagctac cattgatatc
    88741 tttttggcca acttgtttac gcactgctgc tgggtaggtc cctttgcttt caatagaaaa
    88801 gtcaatcaaa aattgtccca aagcagtatt aagcatggaa atttccattg taccatctgc
    88861 tttaaccact aatttggctc ttttatcaaa agcaccttga agcatggagg actcttctga
    88921 gttttcttta ttagctttaa agtttagcgt ataggttcct tctgtgagat tgttaataga
    88981 aacctcacct gcttgataag actcgatggt atcttttaac agtcgatgag tatcgtcgag
    89041 tagcttacta tctttaattt ctttgtaaga atccttgatg acttgaagtt tctcagccag
    89101 atctttgacc gcgtctttgt tgctttcttt agcaataatc gcatccgctt ctttgatagc
    89161 tttttccaaa gtggtgacat ccaactttgt tgattgtctg tcttcagcag tcacatgttg
    89221 tttttgtttg gcagatacaa aatggatttg accatctttc ttggtaacgg taatggtaac
    89281 gtcttcaaat ccttttgaag atatcacgat tgtattttct ccatctttga aagcttttgt
    89341 tccaagatga agccctgtca tattcgagac ccagccatta gtatctttta cagaatctga
    89401 aataagatct ttataaactg taccattgac tgtaaccttt gtgatttgct gagtcaatgc
    89461 ttttatctgt ttgttatcag aataacgatc aatttctgga aataaaattg caccatcttc
    89521 ttgactcaat tttgttatta atgacaagtt agcagtattt ttcccagatt taacaacttt
    89581 ttgtgtgcct tggttttgtg gcactgtttt atcactgagc acatcttttt ttaatgaatc
    89641 ctgatgatct gttgttccta atttttgagc tgaaataaag gtcactttat cgcccttttt
    89701 aataaaggta attaggatat caccatcttt tttattaaca atagtcaatt catgcttacc
    89761 gtctttaata aggttagcat tgatcttaat cccttggtag ttaatatcaa aggttcgctc
    89821 gccttccagg cttttttcat agacatcatt atcaacaata accttttcaa tatgtttata
    89881 atactctttt ccagctgatt gactagcgta agggcctatc tcttcaacta aaagtcgatt
    89941 atcctgagtt aaagctactg ttgtcacgag ttgtgactga actaaaggct cttgtgattt
    90001 tacagtttga gtagcctgaa tgagaacaag ggcagatatt gccacaaacg cacatttgct
    90061 gatttttttc attttcaatc aactttctaa aaatttttat gaataagcta acttttttat
    90121 taactgaact taatctatca ctttgtgatt attttgtcaa gattgtttcc aatggtccaa
    90181 ttgtctgtta aaaagctcca ctatgtgagc caagacacta gcaataagcc tggattgata
    90241 atgatgatat ctctgataaa agaattcctc tacaacaata ttactgagat aaagctagcc
    90301 ttaggatagt tattactagg gctgattcaa tcattacttc attcacaaaa catgtaacac
    90361 gttataaact ccataattgt gttaggagac aacatgagat gtcactactg catattcatc
    90421 acaataaaaa aaaggcaata gccctaatcg tgctattgtc tcaaaatcat ttatttactt
    90481 gaaactttat cgtgttacac caacagttta aaaggcctaa ctcccgctaa gaaaattaag
    90541 ccttaagaaa agtcattagt tattagtttt tactcttgcc aataacatat gttagctgtt
    90601 cagcctgctg agctgtaaag gtacgataag aaatcttgcc taagccgata cagttagact
    90661 ctgaaataag aatagaccca tcttttctaa catcttctac aattgatacg tggccataag
    90721 tgccatcagc gcctgcttgc ccgggtgcaa atgaaatagc ataacctact tttggagtct
    90781 ttgacagggc ataccctgct ttatacttcc aatctccacc atttcccata aaaggatcaa
    90841 attggtaacc caattctttg gcgcgattat acacatacca agtgcattgt ccccaagcat
    90901 aactcgaagc ttgataaccc aagacatcat aactcttaga gagcttataa cctgctggca
    90961 cagatgcaaa actagctgat gactgcactt tcaattcggc tggaatgact ggtgtgccac
    91021 catggtcatc aatccactta tccaggtctt ccataatttg tgcgcgacgt ttaccactac
    91081 cagtagtatc agtaaaataa acacccccgt cacttgcaaa gtttaattga cctcgtgaaa
    91141 acttagccgc ttttaaatct tgaagtgcaa aattgctatt tttgttttta ataatggtat
    91201 cttgtgtcat tttgacaata gcactatcat cattaaactt acttgcttga gtcggatcta
    91261 gatcaaaagc tgcatagcca aacatattag ctccaagcaa agtcgcaatc ccttgagttc
    91321 ctaaagaact ctcagatatc gcaatagcta cgatagctcg aacatccagc ccacttttct
    91381 tttcccattg caatagcttc tcaccattaa tacgtgtgct gtcataggca atgcctgttg
    91441 attttaagta actatcaatc tggtcagctt taataccata acggcgagat aaaagatggt
    91501 gggtataggc atttttacca ctccaatgct ctacatatgc cgcgtatgtg ttgacagaag
    91561 ggatatctat ctcactcaaa tctaaatctg atacgtaagg tgacaacgac tgaataggag
    91621 ttcttacctc tggcaactgt ctcgacaatg aagaagcagg tgccgtatca actttagatg
    91681 gtgatggttt gggctgatca gtcggttttg gctggtcagt tggtttcgaa tggtcagttg
    91741 atttatcatc tacctggttt tctgcttctg ccttgttgtc cgaagaacct acagcagact
    91801 gactagaatc gcttcttttt ttatcatccg cgttaacaag actattagag tttgtttctg
    91861 cagaagcatc aaggggacct tggtcagttt tatctgatgt tgtaggtgct gcatttttat
    91921 tattttcctc ttttgaagaa gaatcactgg tttcatttgt agttgcttta tgcgtctcaa
    91981 gcattacatc ttgagccaac actgtcatgc tttctgctgt cggggctaag agacttagta
    92041 gcatggcaac tcttaatagt ttgtttttat tcatatatta attagtcact tctttctaat
    92101 gtcctcactt tattataaca ttaaagataa gcacaatgca attattttta catgattttc
    92161 ttaatatatc cgaggaatac ggtcacttaa aaggcataga acttcataat tgattgtatt
    92221 acggtaattt gcgatatctg ttgtagaaat atttttttgc tgattgctgc caatcaaagt
    92281 gacttttgtt cctaaaggat atgctttgga aagtcgtatg gtcagttgat ccatcgatac
    92341 acgccctata atttcacaga attgtccatc aactaacacc gaaaagcctt gcatgttcct
    92401 ggtccagcca tctgcataac cgattgggac ggtccctaca tattcagact ttttggcagt
    92461 ataagtagct ccataaccga ctgtatcacc agctgaaatc atcttgacat gcactaagct
    92521 agattctaga gataaagcct cttgcagtgg aaatggtaag cttagatcag aaccacttgg
    92581 attcaaacca taactgacaa ttcctaaacg aacagcatta aaaatggtat cactatgcca
    92641 gatacttgtg gctgaattac tagcatgtac taaacgaggc ttatcctcaa gtccagctat
    92701 tagcttttta aaaaactgta actgctggtt aaatttagta tcatctgcct catcagctgt
    92761 ggcaaaatga gtaaaaatac cttctacatc agcacccatg ctcttcaagc cagcaatcag
    92821 attatcaact tctgttactg agcgaagccc gattcgtccc atgcctgaat caattttgat
    92881 atggacctta agccctttca aatctggcca ttcttgcttg gccatcgcca gccactctaa
    92941 actagccact gtcactgtaa cctggcgagt aatcgccaac tttagctcat ttggcagcaa
    93001 aaccccaaga attaaaatct ctttatcaat acctgcttga cgtaattgca aagcctcatc
    93061 aagatttgac acacagtacc catccacttg aggtaggagt gcttttgaca cctggacagc
    93121 accatgacca taagcatcag ccttgacaac tgcatacgtt tttaccccta gtggaatatg
    93181 cttttgaaca ctggcaacat tctccttaat agcttgtaag ttgacccttg caactgttgg
    93241 gcgatggaaa cttgaaatca ttttttatcc tccaaaataa cactagcctg tacataattg
    93301 ccactatgtg agatgctaat aaaactattt cctttaaacg gagattttgt cagaatggga
    93361 catcctctaa catcatttaa aatctcaata tcttgaaagg ttaaccgccc aatacctgtc
    93421 cctatagcct tagcaaaagc ttccttacct gaccagcgtc ctgccaaata gctgagtcga
    93481 cgtttgtaag gaaaactctc aaaaatagcc aattcctgct cagttaaaat tttttgagca
    93541 aagcgaggat ttctttgata aactttttca atagctgaaa tctcttgtaa gtctattcca
    93601 tgtccaacaa tcattacttt ccaccaaacc ttatttcatc ttaatgttag aagatttaaa
    93661 cagtgagaag ctgagaatta ttctcagctt ctttctatat acctaacttt gtcctgttgt
    93721 gtctcgttct tatgagaagg atttacgacc gtgacaattt ttgaattttt tgcctgaacc
    93781 acatggacaa gcttcgttac gctccacttt gggtaaatca tcggtgttag ctgactgctg
    93841 cgattggatg ttttgaggtg ctgctgttgt ggcacgttga cttgcacgtt cacgttcttg
    93901 ttcgtgaatt tgtgctttca tcatggtacg tgttacatca aactcgatag caccaatcat
    93961 atcttggaac atcttgaaac cttctgcttg gtattccacc acagggttat tttgagcata
    94021 cccccgaagt ccaacagcat tacgaagttg atctaaggca tcaatgtgtt cagtccattt
    94081 gttatccaca atcatcaaaa tgagtacttt ttggaattca ataatggctt cttgatcacg
    94141 aagttttgat agttgctggt catagatagc aagcgctctt tgataaagct tctctttgat
    94201 ttgatcatct tttaaaccac gtaactcttt agcactaata gactcttctg gtaccagcga
    94261 ggtcctagca aaagttacaa tagcatctat agcatcttta cgattgctac gtgcatgagc
    94321 atctacagca cggtcgatag tacgcttgat catagcttta atttctgggc caagatctcg
    94381 attagcagtt atgacatcac gacggttagc atagataatt tcacgctgtt cacgcatcac
    94441 atcatcatat tgtaagacct gtttacgggt atcgtagtta tttccttcaa cccgtttttg
    94501 agcagattcc acttgacgac ctaacatacc tgatttaata acggtgtctt cttcatctaa
    94561 tttcatccga tccaaaaagg cttttatacg atcagagccg aaacgtctca tcaaatcatc
    94621 ttctaatgaa agatagaatt gggattcacc tggatctcct tgacgacctg aacgcccacg
    94681 aagctggtta tcgatacgac ggctttcatg acgctctgta ccaatgacac ataacccacc
    94741 aagttcacga acaccttcac caagcttgat atcagtacca cgaccagcca tgttagttgc
    94801 gattgtaaca gcaccacgtt gcccagcatt cataatgatt tgagcttctt taaagtgatt
    94861 tttagcattc aaaacctcat gaggaatccc tgcttcaacc agcttgcgtg aaatcaaatc
    94921 actagtttca acagcaaccg tacctacaag gataggttgt ccttttgcat gacgcgtttt
    94981 aacgtcttcc acaactgctc taaactttga ttctaaggtc gggtaaagca aatcagtgtg
    95041 atcaatacgg gcaattggac gattggttgg aattggaata atacgcatgt tataaacttc
    95101 gcgaaattct tcttcctcgg tcttcgcagt accagtcata cctgccaatt ttttgtacat
    95161 acgaaacata ttttggtagg tgattgaggc gctggttttt gattcttcct gaatacgaac
    95221 gccttctttt gcctcaatag cttggtgcaa gccgtctgag aagcgacgcc cttccatcgt
    95281 acgacctgta aattggtcaa caataagaat ctcaccatct tcgctgacca cataatcgat
    95341 atctaacaac ataatatagt ttgcacgaag ggcgttgtct ataaagtgag tcaaggctac
    95401 attttcaata tcgtaaagat tgctcaagtt aaaataactc tcagctttat caatacctga
    95461 atcgcttaat ccaatcgttt tagtgggcac atcaataaca taatccactg acgtcagagt
    95521 ttttacaaac atgtcagcac gaatatacaa ttgattggtt tcagagctaa cagcaccaga
    95581 aacaattaaa ggtgtccttg cctcgtcaat taagactgag tccacttcat caaccaaggc
    95641 aaaattgagt gggcgttgta ccatgtcttc ctggcgaaca accatgttgt cacgaaggta
    95701 atcaaaaccg acttcagagt tggttgaata agtaatatca caattataag cttcacgttt
    95761 ttcagcagga gacttagcag ctaggttgat cccaactgaa agacctaacc agctatacac
    95821 ttcacccatt tcggtagcgt cacgcgttga aagatactca ttaacagtaa taacgtgaac
    95881 accctcacca gcaatagcat tgagataaac tggcatggtg gctgtaagag tttttccttc
    95941 accagtacgc atttcaggga catccccgtt atgaagaaca attcctccca taatttgaac
    96001 acgataaggg aacaagccca acacacgttt tgctgcttca cgaacaactg cgaaagcttc
    96061 aggtaatagt tgttcgaggg tctcaccttt ttgatagcgt tctttaaatt caagtgtttt
    96121 tccttgtaga tctctatccg acaatgacgc catttgatct gcgtaggatt ctactttttt
    96181 tgcaattttt tctaattttc ttagttcgcc tttgtcattt tcgataactt tgcgtagaat
    96241 attggccatt ctctttcctt tcgatcatct aatcatttca ttttaacata aatatgcagg
    96301 cagttcaaga aaggttggta aagttatcag agaaacagag agtcataatt t
//
LOCUS       DAXMQE010000003        78655 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.003, whole genome shotgun sequence.
ACCESSION   DAXMQE010000003 DAXMQE010000000
VERSION     DAXMQE010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 78655)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 78655)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..78655
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.003"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            <1..818
                     /locus_tag="ACF4ZO_000202"
     CDS             <1..818
                     /locus_tag="ACF4ZO_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HFD5485787.1"
                     /translation="QVGVKHLIVFMNKVDLVDDEELLELVEMEIRDLLSEYDFPGDDL
                     PVIQGSALKALEGDTKFEDIIMELMDTVDSYIPEPERDTDKPLLLPVEDVFSITGRGT
                     VASGRIDRGTVRVNDEIEIVGIKEETKKAVVTGVEMFRKQLDEGLAGDNVGILLRGVQ
                     RDEIERGQVIAKPGSINPHTKFKGEVYILSKDEGGRHTPFFNNYRPQFYFRTTDVTGS
                     IELPAGTEMVMPGDNVTINVELIHPIAVEQGTTFSIREGGRTVGSGIVSEIEA"
     gene            1058..1816
                     /gene="tpiA"
                     /locus_tag="ACF4ZO_000203"
     CDS             1058..1816
                     /gene="tpiA"
                     /locus_tag="ACF4ZO_000203"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004807 - triose-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HFD5485788.1"
                     /translation="MSRKPIIAGNWKMNKNPQEARAFVEAVASKLPSTDLVDVAVAAP
                     AVDLVTTIEAAKDSVLKVAAQNCYFENTGAFTGETSPKVLAEMGADYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGLTPIVCCGESLETYEAGKAVEFVGAQVSAALAGLSAEQV
                     ASLVLAYEPIWAIGTGKSATQDDAQNMCKAVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVKDYMACPDVDGALVGGASLEAGSFLALLDFLN"
     gene            complement(1915..3150)
                     /locus_tag="ACF4ZO_000204"
     CDS             complement(1915..3150)
                     /locus_tag="ACF4ZO_000204"
                     /EC_number="2.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016755 - aminoacyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyltransferase"
                     /protein_id="HFD5485789.1"
                     /translation="MALIEISQEQFDHYCHSLVHHSFIQTSEMASLMAKRGAKPQFLG
                     LEKDGELKVAAMVFSQKVAGGWRMELNAGPNTNHPEELEHFYTQLKDYAKQKDVIELI
                     LKPYDNYQSFDTDGIPISHPNTDLISLLTALGYKHDGLKTGYPEGEPVWHYVKKLEGI
                     DSSRLTHSFSKKGKALIKKANTFGIKLRQLKRDELHHFKEITEATSDRRDYLDKSLSY
                     YQDFYDSFGDSCEFMVATLNFEDYLNNLKQRQLQLATSINKVKGDLGKNPHSEKKQNR
                     LKELSSQFETFQVRISEALHFLEEYGTKDVFLAGSLFIYTEQEAVYLFSGSYPKFNKF
                     YSPALLQEHAMLKAIHKGIKQYNFLGITGKFDGSDGVLRFKQNFNGFILQKPGTFRCY
                     PFPIKYHFIRLAKKLLNRY"
     gene            complement(3137..4363)
                     /locus_tag="ACF4ZO_000205"
     CDS             complement(3137..4363)
                     /locus_tag="ACF4ZO_000205"
                     /EC_number="2.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016755 - aminoacyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyltransferase"
                     /protein_id="HFD5485790.1"
                     /translation="MYTYKIGISPEEHDQFVLAQPQAGLLQSSKWGKVKDNWKHERIS
                     FYENGVQVAAAACLIRKLPLGFTMIYIPRGPIMDYANFELLDFVIKTLKTFGKSKRAL
                     FVKIDPSLVIKQTLEGKESKENDVTLSIIAFLKKLGVEWSGRTKELEDTIQPRIQANI
                     YAKDFDFDILPKKAKQSIRTATNKGVNVTIGGSELLDDFSALMKKTENRKGIILRGKS
                     YYQKLLDIYAGQSYITMASLDLPEQKKLLIQQLDKALAEQARLTDKSKPSKVAENQKT
                     IARLQKDLTILSEQLAAGKTRIPLAATLTLIYGETSENLYAGMDDNYRNYQAPLLTWY
                     ETAKEAFKRGCRWHNLGGVENQQDGGLYHFKARLNPTIEEFAGEFNIPVGLVSSLAIL
                     TYNLRKKLRSTTNGTN"
     gene            complement(4363..5172)
                     /gene="yidA"
                     /locus_tag="ACF4ZO_000206"
     CDS             complement(4363..5172)
                     /gene="yidA"
                     /locus_tag="ACF4ZO_000206"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HFD5485791.1"
                     /translation="MSIKLVAVDIDGTLLTDDRRITDDVFQAVQEAKAQGVHVVIATG
                     RPIAGVISLLEQLELNHKGNHVITFNGGLVQDAETGEEIVKELMTYDDYLETEFLSRK
                     LGVHMHAITKEGIYTANRNIGKYTVHESTLVNMPIFYRTPEEMTNKEIIKMMMIDEPD
                     LLDAAIKQIPQHFFDKYTIVKSTPFYLEFMPKTVSKGNAIKHLAKKLGLDMSQTMAIG
                     DAENDRAMLEVVANPVVMENGVPELKKIAKYITKSNNDSGVAHAIRKWVLN"
     gene            complement(5628..6929)
                     /locus_tag="ACF4ZO_000207"
     CDS             complement(5628..6929)
                     /locus_tag="ACF4ZO_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HFD5485792.1"
                     /translation="MNEKVFRDPVHNYIHIDNPLIYDLINTKEFQRLRRIKQVPTTAF
                     TFHGAEHSRFSHCLGVYEIARRVTAIFEEKYADIWNKDESLVTMTAALLHDIGHGAYS
                     HTFEALFHTDHETFTQEIITNPETEINAILVRHAPDFPDKVASVINHTYPNKQVVQLI
                     SSQIDCDRMDYLLRDSYFSAANYGQFDLMRILRVIRPVEDGIVFEHSGMHAVEDYIVS
                     RFQMYMQVYFHPASRAVELILQNLLKRAQHLYPKQQAYFQKTAPGLIPFFEKKANLAD
                     YIALDDGVMNTYFQVWMASEDHILSDLASRFINRKILKSVTFDQDSRGELERLRQLVE
                     SVGFDPDYYTGIHINFDLPYDIYRPELENPRTQIEMMQKDGSLAELSQLSPIVKALTG
                     TTYGDRRFYFPKEMLELDDLFAPSKETFMSYISNGHFHFSQ"
     gene            7012..7398
                     /locus_tag="ACF4ZO_000208"
     CDS             7012..7398
                     /locus_tag="ACF4ZO_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HFD5485793.1"
                     /translation="MKLQLTNHIRFGDETEIIQEIHDCEWREKGGYQYLIYQNTDKEK
                     VVIKYNETELTMSRFSNPQSIMKFFAGKKVLIALPTPMGVQQFLTDTSHYHLDCSCQK
                     LDLHYHLLQAQTEMLFASYHLELSWD"
     gene            7628..10309
                     /locus_tag="ACF4ZO_000209"
     CDS             7628..10309
                     /locus_tag="ACF4ZO_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HFD5485794.1"
                     /translation="MSKEQRHEAFYTQSEETVLAQLETSREGLTSAQAKERLAEYGRN
                     ELDEGEKRSLFMKFLDQFKDLMIIILIVAALLSVLTEGMEGLTDAIIILAVVILNAAF
                     GVYQEGQAEAAIEALKSMSSPLARIRRDGHVTEIDSKELVPGDIVLLEAGDVVPADLR
                     LLEANSLKIEEAALTGESVPVEKDLSTAVSEDASIGDRVNMGYQNSNVTYGRGIGVIT
                     NTGMYTEVGHIAGMLANADETDTPLKQNLDNLSKILTYAILVIAAVTFAVGVFLRGQH
                     PLEGLMTSVALAVAAIPEGLPAIVTVVLSLGTQVLAKRNAIIRKLPAVETLGSTEIIA
                     SDKTGTLTMNQMTVEKVYTNGTLQSSSADIAFDNTTLRVMNFANDTKVDPSGKLIGDP
                     TETALVQFGLDHNFDVREAMVAEPRVAELPFDSDRKLMSTIHKQADGKYFIAVKGAPD
                     QLLKRVTQIEENGQIRSITDADKKTILDTNKSLAKQALRVLMMAYKYSDALPTLETEI
                     VEANLVFSGLVGMIDPERPEAAQAVKVAKEAGIRPIMITGDHQDTAKAIAKRLGIIEE
                     DGVDHVFTGAELNELSDEEFQKVFKQYSVYARVSPEHKVRIVKAWQNEGKVVAMTGDG
                     VNDAPSLKTADIGIGMGITGTEVSKGASDMVLADDNFATIIVAVEEGRKVFSNIQKTI
                     QYLLSANMAEVFTIFLATLFGWDVLQPVHLLWINLVTDTLPAIALGVEPAEPGVMKHK
                     PRGRKSSFFDGGVKEAILYQGAFQTILVLGVYGFALMFPEHTSYHDVHADALTMAYVT
                     LGLIQLVHAYNVKSVYQSIFTVGLFKNKLFNYSIPVAFVALMATVVVPGFNQFFHVTH
                     LTITQWLVVIIGSLLMVVLVELVKAVQRSLGQDEKAI"
     gene            complement(10393..11388)
                     /locus_tag="ACF4ZO_000210"
     CDS             complement(10393..11388)
                     /locus_tag="ACF4ZO_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFD5485795.1"
                     /translation="MQRKVTIKDIAELAKTSKTTVSFYLNGKFDKMSEETKNRIKSTI
                     EATNYKPSIAARSLNAKSTKLIGVVIGDITNSFSNQIVKGIESKAQEFGYQIIIGNSN
                     YDPSREDELIEKMLNLGVDGFIIQPTSNFRKYSRIIDIKKKKVVFFDSQLYEHRTNWV
                     KTNNYDAVYDTIQQCIDKGYEHFIMITGNPNLLSTRIERASGFIDVLEANHLTHQEMI
                     IDENQTSSEAIAQFLQGSLTKKSLVFVPNCWALPKVFTAMKSLKFNIPEIGLVGFDNI
                     EWTKFSSPTLTTIIQPAYEEGEQATKILIDDIEGHSQEAKQQIFDCQVNWQESTF"
     gene            complement(11452..13359)
                     /locus_tag="ACF4ZO_000211"
     CDS             complement(11452..13359)
                     /locus_tag="ACF4ZO_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heparinase II/III family protein"
                     /protein_id="HFD5485796.1"
                     /translation="MSLAFTRFKETVNPDFCRNYLLDYQADSYADRKRIADLLLTNTF
                     LFEDNWDMEPCHIPYHLDPITWQKAITDDPEWNFMLNRQTYLQKLILVYLVERDERYL
                     LKAKSFILNWIESAIPLDPKGLATRTLDTGIRCFAWVKCLIYLNLFNALTKQEESLIL
                     ASLEKQLHFLHANYLDKYSLSNWGILQTTAILLADAYYGSNLDIAAATAFARKELTQQ
                     IALQILEDGSQFEQSTMYHVEVLKALLELTALVPDYLPQLRPTLLAMSDYLLKMTGPD
                     HKQIPLGDSDFTDTRDILTLAATILEEPHLKAAAFPTLDIDSLLLLGEKGVHTFEQLP
                     IQTLPTFAHHFEHSGHITINQESYYLFFKNGPIGSSHTHSDQNSLCLYYKGEPLFCDA
                     GRYTYKEEPLRYALKSASHHSTAFLEEQLPEQIDSSWAYLSYPKSNYCHLRQNGHIYF
                     IDGSYQTQFSDRNNYQHDRQILILPPGIFLIIDTIQAQGNHCLVSQFILDNHLDVKTD
                     HLSDLRLISDCPFTIEETILSKKYNQYLTSHKLIKRKPFKDKGCTSTLLVPDDTKVTP
                     LTPLQTGKRNPIETALAWHLKGKQFDYSICVLQEDLIKGEKLVLLNGHKIRGKVVVIN
                     HITNEIIRLKH"
     gene            complement(13446..14267)
                     /locus_tag="ACF4ZO_000212"
     CDS             complement(13446..14267)
                     /locus_tag="ACF4ZO_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000147944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFD5485797.1"
                     /translation="MTGSNKLTKKDYLKTALRAFFLQNGFNYSNYQGIGYANVIYPAL
                     KKHFGSDKKGLYQALEDNCEFYNTNPHFLPFITSLHLVMLENNRSEEETRNIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASLASDGLVLGPILFFLAMNIILTAIKIGSGLYGYK
                     VGTSFIDKLSEQMAVVSRMANIVGVTVIAGLAATSVKITVPITFAAGKVDAANAAQKF
                     VTIQGMLDKIAPALLPALFTLLMYYLIKNKKWTTYKLVLLTVLIGIIGSWLGILA"
     gene            complement(14254..15036)
                     /locus_tag="ACF4ZO_000213"
     CDS             complement(14254..15036)
                     /locus_tag="ACF4ZO_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HFD5485798.1"
                     /translation="MDINLLQALLIGLWTAFCFSGMLLGIYTNRCIILSFGVGIILGD
                     LPTALSMGAISELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVTPEAALALST
                     PIAVAIQFLQTFAYTAFAGAPETAKKQLQKGNIRGFKFAANGTIWSFAILGLGLGLLG
                     ALSMDTLLHLVDYIPPVLLNGLTVAGKMLPAIGFAMILSVMAKKELIPFVLIGYVCAA
                     YLQIPTIGIAIIGIIFALNEFYNKPKQVDATTVQGGQQDDWI"
     gene            complement(15055..15543)
                     /locus_tag="ACF4ZO_000214"
     CDS             complement(15055..15543)
                     /locus_tag="ACF4ZO_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFD5485799.1"
                     /translation="MTQPNIIMTRVDERLIHGQGQLWVKYLNCNTVIVANDAVSEDKI
                     QQSLMKTVIPSSIAIRFFSIQKVIDIIHKASPAQSIFIVVKDLQDAKRLVEGGVPITE
                     INIGNIHKTDDKVAITQFISLGETDKSAIRCLAHDHQVVFNTKTTPAGNSASDVDILD
                     YI"
     gene            complement(15579..16778)
                     /locus_tag="ACF4ZO_000215"
     CDS             complement(15579..16778)
                     /locus_tag="ACF4ZO_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HFD5485800.1"
                     /translation="MTRSLKTIALEPIKQPERFTKEDFLSQEDITQALDLALKQVRLN
                     MDYFKEDFPTPATKDNQYTIMDNTEWTNAFWTGCLWLAYEYSGDDAIKALAQANDLSF
                     LDRVTRDIELDHHDLGFLYTPSCMAEWKLLKTSEAREAALKAADKLVQRYQDKGGFIQ
                     AWGVLGKKEDYRLIIDCLLNIQLLFFASQETGDNRYRDMAINHFYASANHVIRDDASA
                     YHTFYFDPETGDPVKGVTRQGYSDDSAWARGQAWGIYGIPLTYRFLKEPELIQLFKGM
                     THYFLNRLPKDQVSYWDLIFRDDSEQSRDSSATAIAVCGIHEMLKTLPDHDPDKKTYE
                     AAMHSMLRALIKDYANKDLNPGAPLLLHGVYSWHSGKGVDEGNIWGDYYYLEALLRFY
                     KDWNPYW"
     gene            complement(16778..17215)
                     /locus_tag="ACF4ZO_000216"
     CDS             complement(16778..17215)
                     /locus_tag="ACF4ZO_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N-acetylgalactosamine transporter subunit
                     IIA"
                     /protein_id="HFD5485801.1"
                     /translation="MIAIIVMGHGHFASGIVSSLELIAGQQEKVTAIDFTAEMTAADV
                     QDQLSRALIPEEETLVLCDLLGGTPFKVAATLMESLSNTTCNVLSGLNLAMLIEASFA
                     RQTAASFDDLVSGLITCSKEGIVDWKTLSQQEDGTTDDELGGI"
     gene            17551..18345
                     /locus_tag="ACF4ZO_000217"
     CDS             17551..18345
                     /locus_tag="ACF4ZO_000217"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HFD5485802.1"
                     /translation="MENMFSLQGKIALITGASYGIGFEIAKAYAQAGATIVFNDIKQE
                     LVDKGLTAYRELGIEAHGYVCDVTDEAGIQQMVSQIEDEVGVIDILVNNAGIIRRTPM
                     LEMAAEDFRQVIDIDLNAPFIVSKAVLPSMIAKGHGKIINICSMMSELGRETVSAYAA
                     AKGGLKMLTKNIASEFGEANIQCNGIGPGYIATPQTAPLRERQADGSRHPFDQFIIAK
                     TPAARWGATEDLAGPAVFLASDASNFVNGHILYVDGGILAYIGKQP"
     gene            18370..19011
                     /locus_tag="ACF4ZO_000218"
     CDS             18370..19011
                     /locus_tag="ACF4ZO_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HFD5485803.1"
                     /translation="MKIALINENSQAAKNGIIYDALTSVTDKYGYQVFNYGMYGTEGE
                     SQLTYVQNGLLASILLTTKAADFVVTGCGTGVGAMLALNSFPGVTCGFASEPTEAYLF
                     SQINGGNALSIPFAKGFGWGAELNLTLIFERLFAEPMGGGYPKERAIPEQRNARILSD
                     LKKITYRDLLAIVKDIDQDFLKETISGAHFKEYFFANAEPSELVAYLKSVLEQ"
     gene            19040..20041
                     /locus_tag="ACF4ZO_000219"
     CDS             19040..20041
                     /locus_tag="ACF4ZO_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0019200 - carbohydrate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HFD5485804.1"
                     /translation="MSKLLLVGEPLIRVSPNQFQPLTNACDAQLFFGGSEVNIARTLG
                     GFGLEVRLFTALPDNPVGHAFHQFLKQIGVDMTLTAWQGNRVGLYYLENGFGCRASQV
                     YYDRCGSSFSALDKDSLDLAAIFEGIRHFHFSGISLALGKKTQDLIEILAREARKRQV
                     CVSFDLNFRSSMIAAADAKRLFSHFAQYADIIFGMEPLLLDSDDFDMFDRNKADATMI
                     RERLAGLYQRYQLQAIYHTERSNDAQGSNRFKAYAYDGQFYESCEVTTPVLQRVGSGD
                     AFVAGLLYQLLEGNEKQRNLDFAVATASLKCTVAEDQLYHSVQQVEAVLANQRDVQR"
     gene            20046..20681
                     /locus_tag="ACF4ZO_000220"
     CDS             20046..20681
                     /locus_tag="ACF4ZO_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HFD5485805.1"
                     /translation="MGKIEILTKLKANRLVLVVRGESSEEALACSLASIEGGIKTIEV
                     TYTNPFASEVIGQLAERFKEDPEVLIGAGTVLDDVTARQAILAGAQFIVGPNFNRAVA
                     LICHRYSIPYLPGCMTVNEVVTALESGVDMVKIFPGSTVGISFIRAIKSPLPQVEVMV
                     TGGVSSDNLKDWLAAGVDVLGIGGEFNQLASQKQYNLITKKAAHYIKSLRQ"
     gene            20978..21628
                     /locus_tag="ACF4ZO_000221"
     CDS             20978..21628
                     /locus_tag="ACF4ZO_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFD5485806.1"
                     /translation="MIKGIIFDMDGVLFDTEPFYLRRREDFFKTKGIPIDHLNSKDFI
                     GGNLQELWKELLGKNRDDAIVKAITTDYDAYKQAHKPPYQKLLITEVNSCLEQLKKQG
                     IKLAVASNSKRQDVLLALETTQIKDYFEIILAREDVSRGKPYPDIYNKAVQKLGLQKK
                     QLLVVEDSQKGIAAAKAANLTVFAITDYRYGIDQSQADHKIDHLGQLCVKIGCFGS"
     gene            22324..23448
                     /gene="queG"
                     /locus_tag="ACF4ZO_000222"
     CDS             22324..23448
                     /gene="queG"
                     /locus_tag="ACF4ZO_000222"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003092460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0052693 - epoxyqueuosine reductase
                     activity [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA];
                     GO_process: GO:0008616 - queuosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HFD5485807.1"
                     /translation="MTIKAEIKALAKEIGISKIGFTTADNFDYLEKSLRASVEEGRNS
                     GFEHKVIEDRISPERLLESAKTIISIGVAYPHKLPQQPQKTPYKRGKITPSSWGLDYH
                     YVVGEKLDRLSKGIEELCRDFPLQQKAMVDTGALVDTAVAQRAGIGFIGKNGLVISKE
                     YGSYMFLGELITNLEIEPDKPVDYDCGDCRRCLDACPTSCLIGDGSMNAKRCLSFQTQ
                     DKGMMDIEFRKKIKTVIYGCDICQICCPYNKGINNSPATEIDPELAQPELIPFLSLSN
                     GQFKEKFGMIAGSWRGKNILQRNAIIALANAHDKTAVVKLIEIIDKNNNPIHTATAIW
                     ALGEIVKKPNDEMLAFMSHLTLKDEDSQKELELIRRKWQV"
     gene            23517..24615
                     /gene="prfB"
                     /locus_tag="ACF4ZO_000223"
     CDS             join(23517..23588,23590..24615)
                     /gene="prfB"
                     /locus_tag="ACF4ZO_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889043.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016149 - translation release factor
                     activity, codon specific [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HFD5485808.1"
                     /translation="MEVAEIRQKIVENKEKLTSFRRSLDLDRLEEEIALLENHMTEPD
                     FWNDNIAAQKTSQELNELKGKYDTFHNMQELSDETELLLEMLDEDDSLKEELEENLMQ
                     LDKIMGAYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDLLLRMYTRFGNANGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFASVE
                     VMPELDDTIEVEVRDDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVSSTVDRT
                     QYGNRDRAMKMLQAKLYQLEQEKKAQEVDALKGDKKEITWGSQIRSYVFTPYTMVKDH
                     RTNFELAQVDKVMDGEINGFIDAYLKWRIED"
     gene            24634..25326
                     /gene="ftsE"
                     /locus_tag="ACF4ZO_000224"
     CDS             24634..25326
                     /gene="ftsE"
                     /locus_tag="ACF4ZO_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HFD5485809.1"
                     /translation="MALIEMSGVTKKYRRSTTALRDVNVSVNQGEFVYLVGPSGAGKS
                     TFIKLLYREEQLTTGKLYVGEFNLTKLKARDVPILRRHIGVVFQDYKLLPRKTVFENV
                     AYAMEVIGEKRRHIKKRVPEVLDLVGLKHKMRSFPSQLSGGEQQRVAIARAIVNNPKL
                     LIADEPTGNLDPEISWEIMQLLERINVQGTTILMATHNSHIVNTFRHRVVAIEDGRIV
                     RDEEKGDYGYDD"
     gene            25319..26248
                     /gene="ftsX"
                     /locus_tag="ACF4ZO_000225"
     CDS             25319..26248
                     /gene="ftsX"
                     /locus_tag="ACF4ZO_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="permease-like cell division protein FtsX"
                     /protein_id="HFD5485810.1"
                     /translation="MIRYFFRHIWESIKNLKRNFWMTFASVSMVAVTLTLVGVFAATL
                     LNIQRVASGVENNVHINTYLQVDSTDAAKVIQNTAGEPVNNDNYHSVYDKIAQIKGVK
                     KITFSSKDEQLKKLQETLGDVWNMYDQDTNPLQDIYLIETQTPKQVKAITKKIRTIEG
                     VEAADYGGINSDKLFKFSTLIQTWGLIGTAMLLFVAVFLISNTIRMTIMSRKRDIEIM
                     RLVGAKNSYIRGPFFFEGAWVGLLGAVLPSLLIYYGYDLVYKHFAQELQRNNLSMYPL
                     DPYVYYLIGALFVIGIMIGSLGSVLSMRRYLKF"
     gene            complement(26558..27193)
                     /locus_tag="ACF4ZO_000226"
     CDS             complement(26558..27193)
                     /locus_tag="ACF4ZO_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFD5485811.1"
                     /translation="MKIYKTINHIAGENTYYLVNDQAVILIDPGSNGQEIISKIKSFE
                     KPLVAILLTHTHYDHIFSLDLVRDAFDHPPVYVSEKEAAWLSSPDDNLSGLGRHDDII
                     NVIARPAENFFKLKQPYQLNGFEFTVLPTPGHSWGGVSFVFHSDELVVTGDALFRETI
                     GRTDLPTSNFEDLITGIRQELFTLPNHYRVYPGHGPSTTICHEKNANPFFH"
     gene            27424..28188
                     /locus_tag="ACF4ZO_000227"
     CDS             27424..28188
                     /locus_tag="ACF4ZO_000227"
                     /EC_number="1.1.1.304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019152 - acetoin dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_process: GO:0045150 - acetoin catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="(S)-acetoin forming diacetyl reductase"
                     /protein_id="HFD5485812.1"
                     /translation="MSKVAIVTGAGQGIGFAIAKRLHADGFKIGILDYNEETAQAAVD
                     KLSPEDAVAVVADVSKRDQVFDAFQKVVDTFGDLNVVVNNAGVAPTTPLDTITEEQFE
                     KAFAINVGGTIWGSQAAQKHFRELGHGGKIINATSQAGCEGNPNLTVYGGTKFAVRGI
                     TQTLAKDLASEGITVNAYAPGIVKTPMMFDIAHEVGKNAGKDDEWGMEQFAKDITLKR
                     LSEPEDVANAVGFLAGDDSNYITGQTIVVDGGMVFH"
     gene            28338..30797
                     /locus_tag="ACF4ZO_000228"
     CDS             28338..30797
                     /locus_tag="ACF4ZO_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HFD5485813.1"
                     /translation="MTQKKLRKYAVVDLEATGAGPNASIIQVGIVIIQGNKIIDSYET
                     DVNPHESLDEHIVHLTGITDKQLAKAPDFGQVAHHIYQLIEDCIFVAHNVKFDANLLA
                     EALFLEGYELTIPRVDTVELAQLFFPRFEKYNLSHLSRQLNIDLAEAHTAIADARATA
                     ILFLRLLQKIESLPIECLESLLVYSDSLLFETAMVIQEGLAKAKPYDPNKYIKIRQIL
                     LPKGSKALKPYQISKSFPINMALLGLEERPKQTQFAQLIDEDYHQGVASFIEAQTGIG
                     KTYGYLLPLLAKEDQNQIIVSVPTKLLQDQLMAGEVAAIQEQFHIACHSLKGPANYLK
                     LDSFADSLDQNDQNRLVNRYKMQLLVWLLETKTGDLDEIKQKQRFAAYFEQLKHDGDI
                     KQSSEFYDYDFWRVSYEKAKTARLLITNHAYFLHRVQDDKDFTRNKVLVFDEAQKLML
                     QLDQLSRHQLNLTVFLQTIQAKLSNPLPLLEKRLLESLSFELGQVSSDYYQNKEHQLA
                     HDWSRIAGYAKELTGADYQELQAFFATSDGDYWLSSEKQEEKRVTYLNSASKAFIHFQ
                     QLLPETVKTYFVSATLTISSEVTLADLLGFEEYLYHVIEKDKKQDQLVLVDQEAPIVT
                     EVSDQIYVEAIAKRIESLKQEGYPILVLFNSKKHLLLVSDYLDQWQVSHLAQEKNGTA
                     YNIKKRFDQGEQTILLGLGSFWEGVDFIQADRMITLIARLPFDNPEDFFVKKMSHYLL
                     EKGKNPFRDYFLPMTILRLKQAIGRTMRRQDQKSVVIILDRRLLTKSYGQVILEGLGQ
                     EFLISQQNFHDCLVETDCFLI"
     gene            31132..32325
                     /locus_tag="ACF4ZO_000229"
     CDS             31132..32325
                     /locus_tag="ACF4ZO_000229"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HFD5485814.1"
                     /translation="MPKLSKRVLEMKESVTLAAGARAKALKAQGRDVLNLTLGEPDFF
                     TPEHIQDKAIESIQNGTASFYTNASGLPELKAAIATYLKNQYGYHLSPDQIVAGTGAK
                     FILYAFFMAVLNPGDQVLIPTPYWVSYSDQVKMAEGQPIFVQGLEENQFKVTVDQLER
                     ARTSKTKVVLINSPSNPTGMIYGAEELRAIGEWAVHNDILILADDIYGSLVYNGNQFV
                     PISTLSEAIRRQTITVNGVAKSYAMTGWRVGFAAGEPEIISAMSKIIGQTTSNLTTVS
                     QYAAIEAFCGSQSSLEEMRLAFEERLNITYPLLCQVPGFEVVKPQGAFYFFPNVKKAM
                     EMTGFSDVTSFANAILEEVGLAVVSGAGFGAPENVRLSYATDIETLKEAIRRLHVFME
                     SNEIN"
     gene            32346..33692
                     /gene="asnS"
                     /locus_tag="ACF4ZO_000230"
     CDS             32346..33692
                     /gene="asnS"
                     /locus_tag="ACF4ZO_000230"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004816 - asparagine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006421 - asparaginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HFD5485815.1"
                     /translation="MSKKLISIVNVKDYVGQEVTIGAWVANKSGKGKIAFVQLRDGSA
                     FFQGVAFKPNFIEKYGEESGLEKFDVIKRLNQETSVYVTGIVKEDERSKFGYELDITD
                     LEIIGESHEYPVTPKEHGTDFLMDNRHLWLRSRKQMAVMQIRNAIIYATYEFFDQNGF
                     IKFDSPILSENAAEDSTELFETDYFGKPAFLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSFLSHEESLDLQEAYVKALIQGVLDRAPQALDILERDVE
                     ALKRYITEPFKRVSYDDAITLLQEHEADEDTDYEHLEHGDDFGSPHETWISNYFGVPT
                     FVVNYPASFKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREDNYDALVAKMDEL
                     GMDKSEYDFYLDLRKYGSVPHGGFGIGIERMVTFVAGTKHIREAIPFPRMLHRIRP"
     gene            34122..35012
                     /gene="rapZ"
                     /locus_tag="ACF4ZO_000231"
     CDS             34122..35012
                     /gene="rapZ"
                     /locus_tag="ACF4ZO_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002282100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HFD5485816.1"
                     /translation="MSDKHINLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALVPK
                     FLELIEQTNENRRVALVVDMRSRLFFKEINSTLDSIESNPSIDFRILFLDATDGELVS
                     RYKETRRSHPLAADGRVLDGIRLERELLSPLKSMSQHVVDTTKLTPRQLRKTISDQFS
                     EGSNQASLRIEVMSFGFKYGLPLDADLVFDVRFLPNPYYQVELREKTGLDEDVFNYVM
                     SHPESEVFYKHLLNLIVPILPAYQKEGKSVLTVAIGCTGGQHRSVAFAHCLAESLATD
                     WSVNESHRDQNRRKETVNRS"
     gene            35009..35986
                     /locus_tag="ACF4ZO_000232"
     CDS             35009..35986
                     /locus_tag="ACF4ZO_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HFD5485817.1"
                     /translation="MKNPKMTVIGGGTGISIILKSLRNEAVDITAVVTVADDGGSSGE
                     LRNAMQLAPPGDLRNVLLAMSDMPKFYERVFQYRFNESDGALAGHPLGNLIIAGISEM
                     QGSTYNAIQILTKFFHITGKIYPSSEQALTLHAVFKDGHEVAGESSIAKYQGMIDHVY
                     VTNTYNDQKPQASRKVVEAILESDMIVLGPGSLFTSILPNLVIPEIKEALRQTKAEVV
                     YICNIMTQYGETEQFSDADHVAVLNQHLGRDLIDTVLVNVAKVPQAYMNSNKFDEYLV
                     QVDHDFAGLCRAAKRVISSYFLRLENGGAFHDGNLVVEELMNLVRIVKQ"
     gene            35983..36894
                     /gene="whiA"
                     /locus_tag="ACF4ZO_000233"
     CDS             35983..36894
                     /gene="whiA"
                     /locus_tag="ACF4ZO_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0043937 - regulation of sporulation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HFD5485818.1"
                     /translation="MSFTTKVKEELIHLSTGDNNELAAIIKLSGSLGLAHQSLHLSIT
                     TENAKIARYIYSFIEDAYVIVPEIRYHQKTNLRKNRVYTVYVEQGVETILADLKLADS
                     FFGLETGIEPQVLSDDNAGRSYLKGAFLTAGSIRDPESGKYQLEIYSVYLDHAQDLAQ
                     LMQKFMLDAKTIEHKSGAVTYLQKAEDIMDFLIIIGAMSCKEDFEAIKLLREARNDIN
                     RANNAETANIAKTISASMKTINNIIKIMDTIGLESLPIELQQVAQLRVKHPDYSIQQV
                     ADALEFPITKSGVNHRLRKINKIADDL"
     gene            37027..38424
                     /locus_tag="ACF4ZO_000234"
     CDS             37027..38424
                     /locus_tag="ACF4ZO_000234"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016805 - dipeptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="C69 family dipeptidase"
                     /protein_id="HFD5485819.1"
                     /translation="MACTTILVGKKASYDGSTMVARTEDSQNGDFTPKKMIVVKPEDQ
                     PRHYRSVQSSFEMDLPDNPMTYTSVPDALGKDGIWAEAGVNEANVTMSATETITTNSR
                     VLGADPLVASGIGEEDMVTLVLPYIRSAREGVLRLGAILEDYGTYESNGVAFSDEHDI
                     WWLETIGGHHWIARRVPDDAYVTNPNQFGIDHFEFNNPEDYLCSADLKDFIDTYHLDL
                     TYSHEHFNPRYAFGSQRDKDRHYNTPRAWIMQKFLNPEIVQDPRSFALAWCQKPYRKI
                     TVEDVKYVLSSHYQDMGYDPYGSEGTPVSKKVFRPIGINRTSQTAILHIRPNKPQEIA
                     AIQWMAYGSMPFNTMVPFFTQVKTIPDYFANTYENVSTDNFYWTNRLIAALADPHYNH
                     HETDLDNYLEETMAKGHAMLHAVEAQLLAGETVDLEEENQKMSDYVQGETQTLLNKIL
                     FDASNLMTNRFSLSD"
     gene            38576..40123
                     /locus_tag="ACF4ZO_000235"
     CDS             38576..40123
                     /locus_tag="ACF4ZO_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HFD5485820.1"
                     /translation="MKKKILLMMSLISVFFAWQLTQAKQVLAEGKVKVVTTFYPVYEF
                     TKGVIGNDGDVSMLMKAGTEPHDFEPSTKDIKKIQDADAFVYMDDNMETWVSDVKKSL
                     TSKKVTIVKGTGNMLLVAGAGHDHHHEDADKKHEHNKHSEEGHNHAFDPHVWLSPYRS
                     ITVVENIRDSLSKAYPEKAENFKANAATYIEKLKELDKDYTAALSDAKQKSFVTQHAA
                     FGYMALDYGLNQISINGVTPDAEPSAKRIATLSKYVKKYGIKYIYFEENASSKVAKTL
                     AKEAGVKAAVLSPLEGLTEKEMKAGQDYFTVMRKNLETLRLTTDVAGKEILPEKDTTK
                     TVYNGYFKDKEVKDRQLSDWSGSWQSVYPYLQDGTLDQVWDYKAKKSKGKMTAAEYKD
                     YYTTGYKTDVEQIKINGKKKTMTFVRNGEKKTFTYTYAGKEILTYPKGNRGVRFMFEA
                     KEPNAGEFKYVQFSDHAIAPEKAEHFHLYWGGDSQEKLHKELEHWPTYYGSDLSGREI
                     AQEINAH"
     gene            40274..40996
                     /locus_tag="ACF4ZO_000236"
     CDS             40274..40996
                     /locus_tag="ACF4ZO_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFD5485821.1"
                     /translation="MPKEQPLYLQIVDDLEVKIKKSMTANDKLLSERELSDLYGVSHI
                     TIRLALKELELRGLIYKKQGKGTYVSGIKEPATDLSSTYSFTEQMKKMGKMPKTEFLS
                     FEQYQVTPYLSGLLEIDVDTDVFELERLRIADDMPLMFERSYIPAQPFQGLSIADLKR
                     KALYDIFAKDYQETIRLAEEEFYASIALDYEAGLLGIKKGDPVLHIIRKTYDDKNILI
                     ELTFSIARADQFRYRVQHHPNG"
     gene            41016..42215
                     /locus_tag="ACF4ZO_000237"
     CDS             41016..42215
                     /locus_tag="ACF4ZO_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFD5485822.1"
                     /translation="MFTKSQEALEALGAAITTKEIKQEPRLWQETMTFFDETRDSLDS
                     FLKRVCKSANGNNVHVIFTGAGTSEYIGNTICPYLKKVGNRQCYLFESVASTDLVAAP
                     DYYLAEEETVLLVSFARSGNSPESVAAVNLINQLVPNSYHLTITCAKDGELAKKAQQD
                     ERSYLYLMPEDANDAGFAMTGSFTCMMLAALLIFDDATDLSQKQSYVADMVFAGQAIL
                     DQEERLQELADLGFECLVYLGSAGLAKLTQEAQLKMLELTAGQVATLYESSMGFRHGP
                     KSFINDRTLVIGFVNNDAYVRQYDLDMLEEIQADGIALKILALLQGGDINFSEDQFRL
                     DTRHLLPDAYLAFPMILVAQTLALLTAVTLGNSPDTPSATGTVNRVVKGVTIHPYPTS
                     SRQCNKA"
     gene            complement(42312..42572)
                     /locus_tag="ACF4ZO_000238"
     CDS             complement(42312..42572)
                     /locus_tag="ACF4ZO_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HFD5485823.1"
                     /translation="MRKDIHPDYRPVVFLDTTTGYQFLSGSTKASKETVEFEGETYPL
                     IRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAK"
     gene            complement(42687..43628)
                     /locus_tag="ACF4ZO_000239"
     CDS             complement(42687..43628)
                     /locus_tag="ACF4ZO_000239"
                     /EC_number="3.1.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004527 - exonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008441 - 3'(2'),5'-bisphosphate
                     nucleotidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HFD5485824.1"
                     /translation="MITTFETILDKIKAHQTIIIHRHQNPDPDALGSQAGLKEIIAQN
                     FPDKKVLMTGFDEPSLAWISQMDQVTDKDYKEALVIITDTANRPRIDDERYTLGQCLI
                     KIDHHPNDDVYGDFYYVDTSASSASEIIADFAFSQNLTLSDKAAKLLYTGIVGDTGRF
                     LYASTTSKTLSIASQLRHFEFDFAAISRQMDSFPLKIAKLQSYVFEHLTIDESGAAYV
                     LVSQETLKHFDVTLAESSAIVCAPGKIDNVQAWAIFVELTDGNYRVRMRSKEKIINGI
                     AKRHGGGGHPLASGANSASLEENQAIFRELIAVCQEI"
     gene            44022..44471
                     /locus_tag="ACF4ZO_000240"
     CDS             44022..44471
                     /locus_tag="ACF4ZO_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HFD5485825.1"
                     /translation="MALAKIVYASMTGNTEEIADIVANKLQELGHDVDIDECTTVDAS
                     EFENADIAVVATYTYGDGDLPDEIVDFYEDLQDLDLEGKIYGVVGSGDTFYDYFCKSV
                     DDFSEQFALTGAIKGAEPVKVDLAAEDEDIDRLEAFAEQLSQAVNNL"
     gene            44647..44931
                     /locus_tag="ACF4ZO_000241"
     CDS             44647..44931
                     /locus_tag="ACF4ZO_000241"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HFD5485826.1"
                     /translation="MRLEEIRQEINGIDHHLVALLEKRMALVEQVTAYKLANHLPVLD
                     QARENQILDRVSYLVKDQAFEPAIHETFKTIMSLSRQYQTQHLTGGDIND"
     gene            44924..46186
                     /locus_tag="ACF4ZO_000242"
     CDS             44924..46186
                     /locus_tag="ACF4ZO_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="HFD5485827.1"
                     /translation="MIKSIATLPKPSLKEALGLIGLALPIGVAVGVIDVIFGKGFLFL
                     SEYRDHHLFLLLPFLALAGLVIVFLYDKLGKEVRQGMGLVFEVGHGQKDQISPILIPL
                     ILFSTWVTHLFGASAGREGVAVQIGATISHYCRRFVTSQEAARHLLIMGMAAGFAGLF
                     QTPIAAVVFALEVLLVGTLRYCALLPSLVAACVASWTSHSLGLEKFTIVLEETLTITP
                     LTLVKLIGLGLIFGLVGNSFAYLLGWFKPYLSQKLPNPYLRIAFIGVLLSICLMIGHV
                     GRYSGLGTHLLAAAFSGQTILTYDWLLKMIVTVISLSAGFQGGEVTPLFAIGASLGIV
                     LAPYLGLPVLLVAALGYTTVFGSATNTFWAPIFIGIEVFGPENALAYFVTSAAAYMVS
                     HRHSIYSYQKVVMINLKDMTVNQMDLKK"
     gene            46301..46648
                     /gene="rplS"
                     /locus_tag="ACF4ZO_000243"
     CDS             46301..46648
                     /gene="rplS"
                     /locus_tag="ACF4ZO_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000311 - plastid large ribosomal subunit
                     [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HFD5485828.1"
                     /translation="MNPLIQSLTEGQLRSDIPNFRPGDTVRVHAKVVEGTRERIQIFE
                     GVVISRKGQGISEMYTVRKISGGIGVERTFPIHTPRVDKIEVIRHGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            46895..46966
                     /locus_tag="ACF4ZO_000244"
     tRNA            46895..46966
                     /locus_tag="ACF4ZO_000244"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:46928..46930,aa:Arg,seq:cct)
     gene            47278..47569
                     /locus_tag="ACF4ZO_000245"
                     /pseudo
     CDS             47278..47569
                     /locus_tag="ACF4ZO_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056811.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein RodA"
     gene            47672..48232
                     /locus_tag="ACF4ZO_000246"
     CDS             47672..48232
                     /locus_tag="ACF4ZO_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HFD5485829.1"
                     /translation="MNYQDYIWDLGGTLLDNYELSTQAFVQTLAFFSLPGDHDAVYQK
                     LKESTAIAVATFAPNEPEFLHVYRLREADKLAQPIWCLGAKEILEKIATSGSRNFLIS
                     HRDCQVNQLLEQAGLLIYFTEVVTASNGFARKPNPESLFYLKEKYDIDSGLVIGDRLI
                     DKQAGQAAGFNTLLVDGRKNLLEIVT"
     gene            48233..50185
                     /gene="gyrB"
                     /locus_tag="ACF4ZO_000247"
     CDS             48233..50185
                     /gene="gyrB"
                     /locus_tag="ACF4ZO_000247"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HFD5485830.1"
                     /translation="MIEENKHFEKKMQEYDASQIQVLEGLEAVRMRPGMYIGSTAKEG
                     LHHLVWEIVDNSIDEALAGFASHIKVFIEADNSITVVDDGRGIPVDIQAKTGRPAVET
                     VFTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVRVYKNGQIHYQEFKRGAVV
                     ADLEIIGTTDVTGTTVHFTPDPEIFTETTQFDYSVLAKRIQELAFLNRGLKISITDKR
                     SGMEQEEHFHYEGGIGSYVEFLNDKKDVIFETPIYTDGELEGIAVEVAMQYTTSYQET
                     VMSFANNIHTHEGGTHEQGFRAALTRVINDYAKKNKILKENEDNLTGEDVREGLTAVI
                     SVKHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFQRFLLENPQVARKIVEKGILASKA
                     RIAAKRAREVTRKKSGLEISNLPGKLADCSSNDANQNELFIVEGDSAGGSAKSGRNRE
                     FQAILPIRGKILNVEKATMDKILANEEIRSLFTAMGTGFGADFDVSKARYQKLVIMTD
                     ADVDGAHIRTLLLTLIYRFMRPVLEAGYVYIAQPPIYGVKVGSEIKEYIQPGIDQEDQ
                     LKTALEKYSIGRSKPTVQRYKGLGEMDDHQLWETTMDPENRLMARVTVDDAAEADKVF
                     DMLMGDRVEPRRDFIEENAVYSTLDI"
     gene            50553..52277
                     /gene="ezrA"
                     /locus_tag="ACF4ZO_000248"
     CDS             50553..52277
                     /gene="ezrA"
                     /locus_tag="ACF4ZO_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HFD5485831.1"
                     /translation="MSSGIILLIVAIVLLVIIAYLVGVIIRKRNDSLITSLEERKQAL
                     FALPVNDEIEEVKSLHLIGQSQTSFREWNQKWVDLTVNSFADIENHIFEAENLNDTFN
                     FIRAKHEINSVESQLNLVEEDIASIREALNILKEQEEKNSARVTHALDLYEKLQASIS
                     ENEDNFGSTMPEIDKQMKNIETEFSQFVALNSSGDPVEASEVLDRAEEHTIALGQITE
                     QIPAIVAKLEDDFPDQLDDLETGYRRLLEENYHFPEKNIEARFQEIRESIRANSSELV
                     TLDLDRAREENTHIQERIDSLYEVFEREIAAYKVAAKNSKMLPRYLAHVKRNNEQLKN
                     EIARLSRKYILSETESLTVKAFEKDIKEIEDSTLAVAEQFGLQEKPFSELQVTFERSI
                     KTLTNVESGQMDVFAAVKDIEKIESQARHNLDVYVTQLHMIKRYMEKRHLPGIPQDFL
                     SAFFTTSSQLEALMDELSRGRINIEAVSRLSEVATVAIANLEDLTYQVVQNATLTEQL
                     LQYSNRYRSFEAGVQSSFEHALRLFEVENDYQASFDEISYALETVEPGVTDRFVNSYE
                     KTREHIRF"
     gene            complement(52409..52867)
                     /locus_tag="ACF4ZO_000249"
     CDS             complement(52409..52867)
                     /locus_tag="ACF4ZO_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HFD5485832.1"
                     /translation="MTNLEDKLLKGAWGERRLNPEQQRYYLGTYAERVVLSALLDEAQ
                     TKTVKDYLKRELPSLQLVYQPLHLKISSKLAPQLQILYMKLAKENHLPVTIITETHMT
                     SPFAFILHTDHAINLKETRLEVILKQTKNDQLSKQPPEKTKSFWKRFLKK"
     gene            53094..54401
                     /gene="eno"
                     /locus_tag="ACF4ZO_000250"
     CDS             53094..54401
                     /gene="eno"
                     /locus_tag="ACF4ZO_000250"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="surface-displayed alpha-enolase"
                     /protein_id="HFD5485833.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYLGLGTQKAVDNVNNIIAKAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYTYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMIMPVGAPTFKEGLRWGAEVFHALKKILKERGLVTAVGDEGGFAPKFEGTEDG
                     VETILKAIEAAGYEAGENGIMIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQV
                     DYLEELVNKYPIITIEDGMDENDWDGWKVLTERLGKRVQLVGDDFFVTNTEYLARGIK
                     ENAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAG
                     QIKTGSLSRTDRIAKYNQLLRIEDQLGEVAQYKGIKSFYNLKK"
     gene            55171..55332
                     /gene="sagA"
                     /locus_tag="ACF4ZO_000251"
     CDS             55171..55332
                     /gene="sagA"
                     /locus_tag="ACF4ZO_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TOMM family cytolysin streptolysin S"
                     /protein_id="HFD5485834.1"
                     /translation="MLKFTSNILATSVAETTQVAPGGCCCCCTTCCFSIATGSGNSQG
                     GSGSYTPGK"
     gene            55554..56504
                     /gene="sagB"
                     /locus_tag="ACF4ZO_000252"
     CDS             55554..56504
                     /gene="sagB"
                     /locus_tag="ACF4ZO_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptolysin S biosynthesis dehydrogenase SagB"
                     /protein_id="HFD5485835.1"
                     /translation="MSFFTKEQQPKENCPPITVEKARQLFEFNTNHLSLSDYHHQTVL
                     KTSKQLVAQHLMPNATDNLSQHFLMNYKANNNYLGFQASIVDFFTDSAVANFSSSYVY
                     ESQEKIIRLPKPTKISTALSTCIIKRRSHRQFSDRQMPLQDLSNILYYACGVSSQASI
                     RDGASDKITLRNCASGGGLYPIHLVFYARNISKLIDGFYEYLPYQHALRCYRHSSEEN
                     VRDFAEYGAINAENCNIIIIYVYHYIKNTRKYGNQATAYAFIESGEIAQNIQLTATAL
                     TYGSIDIGGYNKEYLQELLDLDGLGEHVIHMTLVGTKESQ"
     gene            56501..57559
                     /locus_tag="ACF4ZO_000253"
     CDS             56501..57559
                     /locus_tag="ACF4ZO_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptolysin associated protein SagC"
                     /protein_id="HFD5485836.1"
                     /translation="MKYQLNSNVRVVTFQDTFCFRKGIWDFNEAILDLTQEPQNLKIV
                     YQEIVSQLVKGVAIDTETYENTLEPETFANLMEVISGLYYNDMLMLEDDYNLEENIMK
                     ILMGNFRFMAQAGHMVSNDPVLFISDSTYVNESAELLAEQLHLQLQVASDDLKMLIQQ
                     TDVSSRLDALEHRRNMNCLSDALCDYQSIIICQERLNIMMLRHLNEVSVAMKKQLVIG
                     FVDGPFLHTCTLNPPHSADFDSLERRVLARLQDSTLYQHFANQILPATQDVSQAYLPL
                     LNVLMNLVVSEAFIIAQTGSSKFEGRLLSIYLPTLEIQVQDILKMSNSQTQGALAKLK
                     YEDQQISTREIVKKLLDE"
     gene            57579..58937
                     /locus_tag="ACF4ZO_000254"
     CDS             57579..58937
                     /locus_tag="ACF4ZO_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcaO-like family protein"
                     /protein_id="HFD5485837.1"
                     /translation="MLYYYPSFNHIFDELKSLSGNRTGILNQSQVPVCNHPHDVYLKS
                     ITGQMPDYHKQFIGELSQVSYHIIGYGSYYEEALIKYLGESIERYATVIAGDLLSDRI
                     VYASYNELKLLHKVMPLEYLQVFTQEQIALSCDLQMMMCDKMVTENDVLGWVKCPMFF
                     EDAEMYVPAQMLCVGYKTNETVGERRIIPGFSTGTASHKTLEAAMCNSLIEYIQIDSM
                     MLSWYTKKPCPKIIVDDPDIEVILEEARLGKDSLYDIIPIDMTVGEDNPLYTFGIILK
                     NKYDEGPYLLFGVQAGLDPKHALLRGIMEASAISYSYYYNLLYQKASLANIECEEPLF
                     LDLDSNVFYYAHPKDQDHKWKAFEPLISGEVLLSDLEDHSGKDKKEDLKTLLAYAKKV
                     SPNAVFLDITPPEALEKGWYVTRVLMPELLEMCIPAFPFANHPRMRQFGGVTNAFVHP
                     MP"
     gene            58912..59583
                     /locus_tag="ACF4ZO_000255"
     CDS             58912..59583
                     /locus_tag="ACF4ZO_000255"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0071586 - CAAX-box protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane glutamic
                     endopeptidase"
                     /protein_id="HFD5485838.1"
                     /translation="MPLSIQCLNLCFLLVTFCPSIPMQAIFGKEDSGYAFNLIGFLRA
                     TLIYDILALVSIYVLSPQITLSLESIDSKTFFMGLVFCVLIVLIELIFLHGLRCWQKK
                     QWLPATFSFVGTTNDWSKIGYPLLLALFEETIYRFLWFNILAFQWHLPTIIVLIVTSF
                     CYALNHLLMGKSIFYAKLVTGIIYGSIYMLTSQLWLVVIMHVGGNLLVECLSHLQTKK
                     KKEVT"
     gene            59580..60263
                     /locus_tag="ACF4ZO_000256"
     CDS             59580..60263
                     /locus_tag="ACF4ZO_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SagF family protein"
                     /protein_id="HFD5485839.1"
                     /translation="MMLLVLLSFLGLTTLWLTSYRRRCLARWHLQWLMALSYQDFLDV
                     LLSLFQFVVIILVLFFYSATINLGEVLTFLTQTSWHWQILCYLVLYLMAIIEMTLLVL
                     ILIFDVLLQKDSRLLFKKITWLPFRQDKPVLSILLLGIVILVDSLFYLGLLILLGEQS
                     LTSLATLILGYGIVKACRYSGWLNVLLAFCLFTIVGLWAVTATLLYGWLVGAMILTVT
                     YLMISCKEY"
     gene            60286..61209
                     /locus_tag="ACF4ZO_000257"
     CDS             60286..61209
                     /locus_tag="ACF4ZO_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD5485840.1"
                     /translation="MSFVQLTNVVKSYKNGKKAVNDVSLSIEAGNIYGLLGPNGAGKS
                     TLINLILGLIPLSSGKITVLGQSQKTIRKISSQIGYVPQDIAVYPDLTAYENVELFGS
                     LYGLKGAQLKKQVLKSLEFVGLHSQAKQFPSQFSGGMKRRLNIACALVHSPKLIIFDE
                     PTVGIDPQSRNHILESIRLLNKEGATVIYTTHYMEEVEALCDYIFIMDHGQVIEEGPK
                     FELEKRYVANLANQIIVTLTDSRHLELADKPDWSLIEDGEKLMLKIDNSDMTSVVHQL
                     TQANITFSEIRHNHLNLEEIFLHLTGKKLRD"
     gene            61218..62345
                     /locus_tag="ACF4ZO_000258"
     CDS             61218..62345
                     /locus_tag="ACF4ZO_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SagG family ABC transporter permease subunit"
                     /protein_id="HFD5485841.1"
                     /translation="MVLFHLIKKESLQIFRNRTALLMMVIFPILMIVILSFAFKSSFN
                     TATTVPKLTIRYQLEGEKTDYQKNFLAFLKVLNQKLHLEAKPSNSLEKDRQRVSEGAL
                     TAVLEVKKNQTIKVITNNINQQNADLINMLVKNYVDNAKTYDSIAALYPQQLNHIRKR
                     SVDYVKVSSIQTSKGMTSADYYAISMFTMITFYSMMSAMNLVLSDRQQRITNRIRLTG
                     VSPSLLVFGKLIGAMLATTVQLSLLYIFTRFVLRVNWGTNEWMLIGITASLVYLSVAI
                     GIGLGISIKNEAFLTVASNTIIPIFAFLGGSYVPLTTLHSSIINQLSNISPIKWVNDS
                     LFYLIFGGQYNPIPVTLIVNISIGTIFIILALIGMRKQVTT"
     gene            62342..63460
                     /locus_tag="ACF4ZO_000259"
     CDS             62342..63460
                     /locus_tag="ACF4ZO_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD5485842.1"
                     /translation="MICFIKTLFVKIKRKKTSYVTFFLMPILTTLLALSLSFSNNNQA
                     KIGILDKDNSQISKQFIAQLKQNKKYDIFTKIKKEHIDHYLQDKSLEAVLTIDKGFSD
                     KVLQGKSQKLNIRSIANSEITEWVKAQTNYLLENYNIIGDVALGNEDTFNRILQKNQQ
                     LNYGVKQVTLTDRSRSKAVSSTTTGFLLILMLGSTSVIYSGILADKSSQLYHRLMLSN
                     LSRFRYMLSYVCVGFVAFTIQIVIMLSLLKVFNISFFVPTSLLLIIFFLFSLLAIGFG
                     LLIGAITQNSQQSSQLANLIVMPTSMLAGCLWPLSITPSYMQAIGKLLPQNWVLSAIA
                     IFQSGGTLSQAWPYLLALMGTALALIIFSSLLLKPTRL"
     gene            64032..66764
                     /locus_tag="ACF4ZO_000260"
     CDS             64032..66764
                     /locus_tag="ACF4ZO_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HFD5485843.1"
                     /translation="MINKKCIIPVSLLTLAITLTSVEEVTSRQNLTYANEIVTQRPKR
                     ESVISDKTNFPVISPYLASVDFGERKTPLPTPDKGVKVTTEQSIAQVRKGPEERTYTV
                     TGKITSVINGWGGYGFYIQDSEGIGLYVYPQKDLGYSKGDIVQLTGTLTRFKGDLQLQ
                     QVTAHKKLELSFPTSVKEAVISELETTTPSTLVKLSHVTVGELSTDQYNNTSFLVRDD
                     SGKSIVVHIDHRTGVKGADVVTKISQGDLINLTAILSIVDGQLQLRPFSLEQLEVVKK
                     VTSSNSDASSRNIVKIGEIQGASHTSPLLKKAVTVEQVVVTYLDDSTHFYVQDLNGDG
                     DLATSDGIRVFAKNAKVQVGDVLTISGEVEEFFGRGYEERKQTDLTITQIVAKAVTKT
                     GTAQVPSPLVLGKDRIAPANIIDNDGLRVFDPEEDAIDYWESMEGMLVAVDDAKILGP
                     MKNKEIYVLPGSSTRPLNNSGGVLLPANSYNTDVIPVLFKKGKQIIKAGDSYKGRLAG
                     PVSYSYGNYKVFVDDSKNMPSLMDGHLKPEKTNLQKDLSKLSIASYNIENFSANPSST
                     KDEKVKRIAESFIHDLNAPDIIGLIEVQDNNGPTDDGTTDATQSAQRLIDAIKKLGGP
                     TYRYVDIAPENNVDGGQPGGNIRTGFLYQPERVSLSDKPKGGARDALTWVNGELNLSV
                     GRIDPTNAAWKDVRKSLAAEFIFQGRKVVVVANHLNSKRGDNALYGRVQPVTFKSEQR
                     RHVLANMLAQFAKEGAKHQANIVMLGDFNDFEFTKTIQLIEEGDMVNLVSRHDISDRY
                     SYFHQGNNQTLDNILVSRHLLDHYEFDMVHVNSPFMEAHGRASDHDPLLLQLSFSKEN
                     DKAESSKQSVKAKKTSKGKLLPKTGDSLVYVITLLGTASLLVPILLLTKGKKES"
     regulatory      66929..67044
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            67042..67542
                     /locus_tag="ACF4ZO_000261"
     CDS             67042..67542
                     /locus_tag="ACF4ZO_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HFD5485844.1"
                     /translation="MTKLTVHDYVHIGLVAALYVVLTITPPLNAISYGMYQFRISEMM
                     NFLAFYHRKYIIAVTLGCMIANFYSFGLIDVFVGGGSTLIFVTLGVILFSKYQKDYLF
                     NGIFNKAFVYFSFFFATSMFTVAIELYFFGAPFLLTWFTTALGELVSLLIGSLIIDKL
                     SQRISF"
     gene            67736..69694
                     /gene="ligA"
                     /locus_tag="ACF4ZO_000262"
     CDS             67736..69694
                     /gene="ligA"
                     /locus_tag="ACF4ZO_000262"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003911 - DNA ligase (NAD+) activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HFD5485845.1"
                     /translation="MKKRIKELTDLLNRYRYDYYTKDAPSVSDSDYDKLYRELVTLEQ
                     SYPEYVLQDSPTQQVGGTILKGFEKYRHQYPLFSLQDAFSREELDAFDKRVKAEFPNA
                     TYLAELKIDGLSISLSYENGFLQVGATRGDGNIGENITENIKKIKDIPHQLSEPLTIT
                     VRGEAYMSRQSFKAINEARQENGETEFANPRNAAAGTLRQLDTSVVAKRQLATFLYQE
                     ASPTARNQQNEVLAELADLGFSVNPYYQLTSSMDEIWDFIKTIEAKRDQLAYDIDGVV
                     IKVNSLAMQEELGFTVKAPRWAIAYKFPAEEKEAEILSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRIGDTVIVYKAGDIIPAVLNVVMSKRNQQEVMLIP
                     KLCPSCGSELVHFEDEVALRCINPLCPSLIQRSLEHFASRDAMNITGLGPAIVEKLFL
                     AGFVHDVADIYQLTKEDFMQLDGIKEKSADKLLAAIEASKSNSAEKLLFGLGIRHIGS
                     KVSRLILEVYGDISALLTAKEEEIARIDGLGSTIAQSLTQYFEQKTAAILVDELKTAG
                     VNMHYSGQKVNSDAALFGLTVVLTGKLNQLNRNEAKDKLEALGAKVTGSVSKKTDLVI
                     AGSDAGSKLEKAKSLGIRIEDEDWLRKF"
     gene            69708..70730
                     /locus_tag="ACF4ZO_000263"
     CDS             69708..70730
                     /locus_tag="ACF4ZO_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HFD5485846.1"
                     /translation="MKKQLRARLIYNPTSGQELMRKSVPEVLDILEGFGYETSAFQTT
                     AQKNSALNEARRAAKAGFDLLIAAGGDGTINEVVNGIAPLKKRPKMAIIPTGTTNDFA
                     RALKVPRGNPSQAAKLIGKNQTIQMDIGRAKKDTYFINIAAAGSLTELTYSVPSQLKT
                     MFGYLAYLAKGVELLPRVSNVPVKITHDKGVFEGQVSMIFAAITNSVGGFEMIAPDAK
                     LDDGMFTLILIKTANLFEIVHLLRLILDGGKHITDRRVEYIKTSKIVIEPQCGKRMMI
                     NLDGEYGGDAPITLENLKNHITFFADTDLISDDALVLDQDELEIEEIAKKFAHEVEDL
                     EQELEE"
     gene            71122..71319
                     /locus_tag="ACF4ZO_000264"
     CDS             71122..71319
                     /locus_tag="ACF4ZO_000264"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HFD5485847.1"
                     /translation="MNPIFALALACFGVSLAEGFLMANLFKAASRQPEIIGQLRSLMI
                     LGVAFIEGTFFVTLVMAFILK"
     gene            71354..72070
                     /gene="atpB"
                     /locus_tag="ACF4ZO_000265"
     CDS             71354..72070
                     /gene="atpB"
                     /locus_tag="ACF4ZO_000265"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HFD5485848.1"
                     /translation="MEEAKIPMLKLGPITFNLTLLAVCIVTIAVIFAFVFWASRQMKL
                     KPEGKQTALEYLISFVDGIGEEHLDHNLQKSYSLLLFTIFLFVAVANNLGLFTKLETV
                     NGYNLWTSPTANLAFDLALSLFITLMVHIEGVRRRGLVAHLKRLATPWPMTPMNLLEE
                     FTNFLSLAIRLFGNIFAGEVVTGLIVQLANYRVYWWPIAFLVNMAWTAFSVFISCIQA
                     FVFTKLTATYLGKKVNESEE"
     gene            72088..72582
                     /gene="atpF"
                     /locus_tag="ACF4ZO_000266"
     CDS             72088..72582
                     /gene="atpF"
                     /locus_tag="ACF4ZO_000266"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045263 - proton-transporting ATP
                     synthase complex, coupling factor F(o) [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HFD5485849.1"
                     /translation="MSITFGELVGNFILVTGSVIVLLLLIKKFAWGAIESILQTRSQQ
                     ISRDIDQAEQSRLSAQQLETKSQANLDASRSQASKIISDAKEIGQLQGDKLVAEATDE
                     AKRLKEKALTDIEQSKSDAISAVKTEMSDLTVLLAEKIMGANLDKTAQSQLIDSYLDD
                     LGEA"
     gene            72582..73118
                     /locus_tag="ACF4ZO_000267"
     CDS             72582..73118
                     /locus_tag="ACF4ZO_000267"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HFD5485850.1"
                     /translation="MTKKEQALIEQYAKSLVEVASEHHSLDALQADVLAILETFVTTN
                     LDQSLSSLAVPHAEKIKLLTLLKGNNSVYMNNFLNLILQNEREAYLYQMLQTVLNEIA
                     IVSNQYDVTVTSSLPLTEEQKSRVRAVVAKKFAVTAGRLIEKVDPSLIGGFIISVNNK
                     VIDTSIRRQLQAFKMNLK"
     gene            73134..74642
                     /gene="atpA"
                     /locus_tag="ACF4ZO_000268"
     CDS             73134..74642
                     /gene="atpA"
                     /locus_tag="ACF4ZO_000268"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HFD5485851.1"
                     /translation="MAINAQEISALIKKQIENFQPNFDVTETGIVTYIGDGIARARGL
                     DNAMSGELLEFENGAYGMAQNLESNDVGIIILGDFSAIREGDVVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPVDGLGDIETTGFRPVETPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTSVAIDAILNQKGQDMICIYVAIGQKESTVRTQVETLRRYGAL
                     DYTIVVTASASQPSPLLFIAPYAGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERSAKVSDDLGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLQENLFNSGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQPLHKPLPVEKQVVILYALTHGFLDDVPV
                     DDILAFEEALYDYFDVHYNDLFETIRTTKDLPEEAALDAAIKAFKEHSNFKS"
     gene            74658..75533
                     /locus_tag="ACF4ZO_000269"
     CDS             74658..75533
                     /locus_tag="ACF4ZO_000269"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HFD5485852.1"
                     /translation="MAGSLSEIKAKIISTEKTSKITSAMRMVSSAKLVKSEQAARDFQ
                     IYASKIRQITTDLLKSELTIGSDNPMLVSRPVKKTGYIVITSDKGLVGGYNSKILKSV
                     MDMITEYHADGDYEIISIGSVGSDFFKARGMNVAFELRGLADQPSFEQVRQIISQSVD
                     MFVNEIFDELYVCYNHHVNSLTSQVRVQQMLPISDLVADEAAEEGVTGFELEPNRHDI
                     LDQLLPQFTESLIYGAIIDAKTAEHAAGMTAMQTATDNAKNVINDLTIQYNRARQAAI
                     TQEITEIVAGANALE"
     gene            75695..77101
                     /gene="atpD"
                     /locus_tag="ACF4ZO_000270"
     CDS             75695..77101
                     /gene="atpD"
                     /locus_tag="ACF4ZO_000270"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017643977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HFD5485853.1"
                     /translation="MSSGKIAQVVGPVVDVMFASGDKLPEINNALIVYKDSDKKQKIV
                     LEVALELGDGMVRTIAMESTDGLTRGLEVLDTGRAISVPVGKETLGRVFNVLGETIDL
                     EEPFAEDVDRQPIHKKAPSFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTQKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLTQ
                     MGIYPAVDPLASSSRALSPEIVGEEHYAVATEVQRVLQRYRELQDIIAILGMDELSDE
                     EKTLVGRARRIQFFLSQNFNVAEQFTGLPGSYVPVAETVRGFKEILEGKYDHLPEDAF
                     RSVGPIEDVIKKAEKMGF"
     gene            77114..77530
                     /locus_tag="ACF4ZO_000271"
     CDS             77114..77530
                     /locus_tag="ACF4ZO_000271"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003088947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HFD5485854.1"
                     /translation="MTQMTVQVVTPDGIKYDHHAKCISVTTPDGEMGILPNHINLIAP
                     LQVHEMKIRRGGEDEKVDWIAINGGIIEIKDNVVTVVADSAERDRDIDVSRAERAKLR
                     AEREIAQAETTHNIDEVRRAKVALRRALNRINVSKK"
     gene            77817..78053
                     /locus_tag="ACF4ZO_000272"
     CDS             77817..78053
                     /locus_tag="ACF4ZO_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009881177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 family protein"
                     /protein_id="HFD5485855.1"
                     /translation="MELLMKIIAFSCHLFFIGLSYQLLISVIDWTKFSHYHPENLGRL
                     RLFVFLLATALGYLVSHCMLELIQISQMLFFEFR"
     gene            78118..>78655
                     /locus_tag="ACF4ZO_000273"
     CDS             78118..>78655
                     /locus_tag="ACF4ZO_000273"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357880.1"
                     /note="adds enolpyruvyl to UDP-N-acetylglucosamine as a
                     component of cell wall formation; gram-positive bacteria
                     have 2 copies of MurA which are active; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HFD5485856.1"
                     /translation="MDKIIIEGGQTRLEGEVVIEGAKNAVLPLLAASILPSKGKTILR
                     NVPILSDVFTMNNVVRGLDIRVDFNEAANEITVDASGHILDEAPYEYVSQMRASIVVL
                     GPILARNGHAKVSMPGGCTIGSRPINLHLKGLEAMGATITQKGGDITAQADRLQGAMI
                     YMDFPSVGATQNLMMAATL"
BASE COUNT        24092 a        13618 c        16513 g        24432 t
ORIGIN      
        1 gtcaagttgg tgttaaacac cttatcgtct tcatgaacaa agttgacctt gttgatgacg
       61 aagagttgct tgaattagtt gagatggaaa ttcgtgacct tctttcagaa tacgatttcc
      121 caggtgatga ccttccagtt atccaaggtt cagctcttaa agctcttgaa ggcgacacta
      181 aatttgaaga catcatcatg gaattgatgg atactgttga ttcatacatt ccagaaccag
      241 aacgcgacac tgacaaacca ttgcttcttc cagtcgaaga tgtattctca atcacaggtc
      301 gtggtacagt tgcttcagga cgtatcgacc gtggtactgt tcgtgtcaac gacgaaatcg
      361 aaatcgttgg tatcaaagaa gaaactaaaa aagctgttgt tactggtgtt gaaatgttcc
      421 gtaaacaact tgacgaaggt cttgcgggag acaacgtagg tatccttctt cgtggtgttc
      481 aacgtgacga aatcgaacgt ggtcaagtta ttgctaaacc aggttcaatc aacccacaca
      541 ctaaattcaa aggtgaagta tatatccttt ctaaagacga aggtggacgt cacactccat
      601 tcttcaacaa ctaccgtcca caattctact tccgtacaac tgacgtaaca ggttcaatcg
      661 aacttccagc aggtacagaa atggttatgc ctggtgataa cgtaacaatc aacgttgagt
      721 tgatccaccc aatcgccgta gaacaaggta ctactttctc aattcgtgaa ggtggacgta
      781 ctgttggttc aggtatcgtt tcagaaatcg aagcttaatt ttaattaagt tcccagaata
      841 gcaatttaag tcagacaact taagtttgaa gaagccccca attcgggggc tttttgctat
      901 cttaaactcc ataaaatgct gataaataag aatgaaaagc tttcagaaaa agggttttta
      961 tttgtgaaaa tattcctaaa atataagcaa ttccttttaa tcgtcggtca tttgtgctaa
     1021 aatagaagat ataaataaaa aagaagaggt atgtgatatg tcacgtaaac caattattgc
     1081 tggtaactgg aaaatgaaca aaaaccctca agaagcaaga gcattcgttg aggctgtagc
     1141 aagcaaatta ccttcaactg accttgttga tgttgccgta gcagccccag ctgttgattt
     1201 ggtaaccact attgaagctg ctaaagattc agttcttaaa gttgctgcac aaaactgcta
     1261 ctttgaaaac acaggggcat tcactggtga aacatcacca aaagtgcttg ctgaaatggg
     1321 agctgactat gttgtgattg gtcactcaga acgccgtgat tacttccatg aaacagatga
     1381 agacattaat aaaaaagcca aagcaatctt tgctaacggt ttaactccaa ttgtttgttg
     1441 tggtgagtct cttgaaactt atgaagctgg taaagccgtt gagtttgtag gtgcgcaagt
     1501 ttcagcagca cttgcaggtc tttcagcaga gcaagtagct tcacttgttt tagcttatga
     1561 gccaatctgg gctatcggta ctggtaaatc agctactcaa gatgatgctc aaaacatgtg
     1621 taaagctgtt cgtgacgtgg tagcagcaga ctttgggcaa gaagttgctg ataaagttcg
     1681 cgttcaatac ggtggttctg taaaacctga aaacgttaaa gattacatgg cttgtccaga
     1741 tgttgacggt gcccttgtag gtggtgcatc acttgaagct ggtagcttcc ttgctttgct
     1801 tgatttcctt aactaagtca tctaaaaaag aaaaggttaa atccttttct tttttagatg
     1861 gcttaactct taatatgaga gaataaaggt gattctacag gcaaatgcat tagcctaata
     1921 gcggtttaat agcttttttg ccaatctaat gaaatgatat ttgattggaa atggataaca
     1981 tctaaatgtt cctggttttt gcaaaataaa gccattgaaa ttctgtttaa agcgcaagac
     2041 accgtctgaa ccatcaaact ttccagtaat accaagaaaa ttatattgtt tgatgccctt
     2101 gtgaattgcc ttgagcatag catgctcttg taatagagct gggctataaa atttattaaa
     2161 tttggggtaa gatcctgaaa agaggtagac ggcctcttgt tcggtataga taaaaagact
     2221 tcccgcaagg aacacatctt tagttccata ctcttcaaga aaatggagag cttcagaaat
     2281 tcttacctga aaggtttcga attggctgga tagttctttt aatctatttt gctttttttc
     2341 agaatgagga tttttgccaa ggtctccttt aactttgttg atgctggttg ctagttgtag
     2401 ttgtctttgt ttaaggttat taaggtaatc ttcaaaatta agagtcgcaa ccataaattc
     2461 acaagagtct ccaaaactat cataaaagtc ctgatagtaa gataatgatt tgtcaaggta
     2521 atctctacga tcagaggttg cttcagtgat ttctttgaaa tggtgtaact catctcgttt
     2581 cagttgacgt aatttaatac caaaagtatt agcttttttt attaaagctt ttcctttttt
     2641 gctgaaggaa tgggttaaac gtgaggaatc aattccttct aactttttaa cgtaatgcca
     2701 aacaggttca ccctcaggat agcctgtttt taaaccgtca tgtttatatc ctaacgccgt
     2761 taaaaggcta ataaggtcag tgtttggatg agaaataggg atgccatcag tatcaaatga
     2821 ctgataattg tcgtaaggtt ttaaaatgag ttcgataacg tctttttgtt tggcatagtc
     2881 tttaagttga gtgtaaaaat gttctaattc ttcgggatga ttggtattag ggcctgcatt
     2941 gagttccata cgccaacctc cagccacttt ttggctaaag accatagcag caacctttag
     3001 ttcaccatct ttttcaagtc caagaaattg tggttttgcc cctcttttag ccatcaagct
     3061 ggccatttct gaggtttgga taaaggaatg atggacgaga ctgtggcagt aatggtcaaa
     3121 ttgttcttgt gaaatttcaa ttagtgccat tagttgtgct ccttaatttt tttcttaagt
     3181 tataggtcaa gatggctaag cttgaaacaa ggccgacagg aatgttgaat tcacctgcaa
     3241 attcttcgat ggtggggttg agtctagctt tgaaatgata gagtccacca tcttgttgat
     3301 tttccacacc tcctaaatta tgccagcggc agcctctttt aaaagcttct ttagccgttt
     3361 cataccaggt taaaagagga gcttgataat tgcgataatt atcgtccatt cccgcataaa
     3421 gattttcaga agtctcgcca taaatcaagg ttagggtggc ggctagtggg atgcgggttt
     3481 tgcctgcagc gagctgctcg cttaaaatgg ttaaatcttt ttgtagccgt gcaatggttt
     3541 tttgattttc tgctacttta ctaggtttac tcttatctgt taatcgtgct tgttctgcta
     3601 aggccttgtc caactgttgg atcaagagtt ttttttgttc aggtaagtct aaactagcca
     3661 tagtaatgta ggactgacca gcataaatat ctagtaattt ttgatagtag gatttgcctc
     3721 gaaggataat gccttttcga ttctcggttt ttttcatcaa ggctgaaaag tcgtctagca
     3781 attcactgcc accaatcgtg acattaacac ctttattggt agcggtacga atggattgct
     3841 tggctttttt gggcaggatg tcaaagtcaa aatccttggc gtagatgttg gcttgtattc
     3901 ttggttgaat agtgtcttcg agttcttttg ttctgccaga ccattcgaca ccaagttttt
     3961 ttagaaaagc aataatagag agtgtcacat cattttcttt gctttctttt ccttctaaag
     4021 tttgtttgat gactaaactt ggatcaattt tgacaaaaag cgctcgtttg ctttttccga
     4081 acgttttgag cgttttaata acgaaatcaa ggagttcaaa attggcgtag tccatgattg
     4141 gcccacgtgg gatataaatc atagtgaaac caagaggaag ttttctgatt aaacaagcag
     4201 cagcagcaac ttgtacccca ttttcataaa agctgatgcg ttcgtgtttc cagttatctt
     4261 tgacttttcc ccactttgaa ctttgaagta agccagcttg tggctgtgct aagacaaact
     4321 gatcatgttc ttcaggagat attccgattt tatatgtata cattagttta atacccactt
     4381 gcgaatagca tgtgccacac cactgtcatt gttggatttg gtgatgtatt tggctatttt
     4441 tttcaattca ggaaccccat tttccatgac aacagggttg gcaacgactt ctaacatagc
     4501 acgatcattt tcagcatccc cgatggccat ggtttgtgac atatctagcc cgagtttttt
     4561 agctaagtgt ttgatggcat tacccttgct gacggttttt ggcatgaact ctaaataaaa
     4621 aggggttgac ttgacgatgg tgtacttatc aaagaaatgt tgaggaattt gcttgatggc
     4681 cgcgtccaaa aggtcaggtt catcaatcat catcattttg atgatttctt tattggtcat
     4741 ttcttcggga gtgcgataga aaataggcat gtttaccaaa gtcgattcat gaactgtgta
     4801 ttttccaata ttccgattgg cagtgtaaat accttctttg gtaatggcat gcatgtgaac
     4861 tcctaatttt cggctcaaaa attccgtttc cagataatcg tcgtaagtca tcaattcttt
     4921 aacaatttct tcgccggtct cggcatcttg caccaagcca ccattaaaag tgataacgtg
     4981 gtttcctttg tggttgagtt ctaattgttc gagtaatgaa atcactccgg caataggtct
     5041 gccagtagca atcaccacat gaacaccttg ggctttagcc tcttggacag cttgaaaaac
     5101 atcatctgta attcgacggt catcagtgag taatgtgcca tcaatatcga cagcaaccag
     5161 tttgatagac atggcatcct ccttgttttt ttgtggttta tcttaaaaat gttctccctc
     5221 ctatcttact aaaaataggt gcttttgtca tgggatggga aaggaaactt aaggaaaaac
     5281 gagagaaaac gttttagttt agctcaatcg cctctctagt aactaaaaag attgaagaaa
     5341 gtactctttc ttcaatctta gaatggagac aaacccagtt tgatgctcaa aaagcatgaa
     5401 ctgctctgct gatttgacaa ctgatttctt atttctgcgt gtgacgtgag ccaaaacagc
     5461 tgctttttgc tgtggcaaaa gtggtgtcaa tactggcagt gacgttacgc gggatttttg
     5521 agaccctagg ctcaaaaata aagcatagaa ttccaaagga actcgctgcc ataagtgcca
     5581 cctaagaaaa gtatcaaaaa agactttttc tgcaatctta aagggtttta ctgactaaag
     5641 tgaaaatgcc cattggaaat ataactcata aaagtttcct tgctaggagc aaagaggtca
     5701 tcgagctcta acatttcctt tggaaaataa aagcgacggt ctccgtaggt tgtccctgtt
     5761 aatgctttga caataggaga taactgagat aattcagcaa ggctcccgtc tttttgcatc
     5821 atttcaatct gagttcttgg attttcgagc tctggtcgat aaatatcata aggcaggtcg
     5881 aagttgatat ggataccggt gtaataatct ggatcaaagc caactgattc gaccaattgg
     5941 cgcaagcgtt ctaactctcc tcgggaatct tggtcaaagg taacagactt cagaattttt
     6001 cgattaataa aacgactggc caaatctgat aagatatggt cttcgcttgc catccagact
     6061 tggaagtaag tattcatgac tccgtcatct agggctatat aatctgctaa attagccttc
     6121 ttttcaaaga aggggatgag tccaggagct gttttttgga aataagcctg ttgcttagga
     6181 tataagtgtt gggctctttt gaggagattt tgtaagatga gctcaacagc acggctggcg
     6241 ggatgaaaat agacctgcat gtacatttga aaacgactga caatatagtc ctcgacagca
     6301 tgcataccac tatgttcaaa gacaatgcca tcttcaacag gtcgaatcac acgtagaatg
     6361 cgcattaaat caaactgacc ataattggca gcagaaaaat aagaatctct taaaaggtaa
     6421 tccatacggt cgcagtcaat ctggctggaa atcagttgca caacttgctt gttaggataa
     6481 gtatgattaa tcacgctggc aactttgtct ggaaaatcag gagcatgacg caccaaaatg
     6541 gcattgattt ctgtctcagg attggtaatt atctcctgag taaaggtctc gtgatccgta
     6601 tggaaaaggg cctcaaaggt atgagaatag gctccatgac caatgtcatg taagagggca
     6661 gccgtcatag tgaccagact ttcatcttta ttccagatat cagcgtattt ctcttcaaaa
     6721 atagctgtca cccgacgggc aatttcgtaa acacctaggc agtgagaaaa acggctatgt
     6781 tctgcgccgt ggaaggtgaa agctgttgta gggacttgtt tgatgcgtcg taagcgttgg
     6841 aattctttgg tattgataag gtcataaatt aatggattat caatgtggat atagttgtga
     6901 acagggtcac gaaatacttt ttcattcata atttttatta tatcaaaaat tgataaaata
     6961 aggagaaatt gatagaataa acagacgagc ttagatatag aaagaagagt tatgaaatta
     7021 cagttaacca accatattcg ctttggagat gagacagaga ttattcaaga aattcatgat
     7081 tgtgagtggc gagaaaaagg gggctatcag tacctcatct atcaaaacac tgacaaggaa
     7141 aaggttgtca tcaagtataa tgagacagaa ctgaccatga gccgtttttc caaccctcag
     7201 tcaatcatga aattttttgc gggcaagaag gtcctgattg ctctacctac accgatgggg
     7261 gttcaacaat ttttgacaga taccagtcat taccacttag attgttcttg tcaaaaattg
     7321 gaccttcatt atcatttgct tcaagctcaa acagaaatgc tatttgcaag ctatcatctt
     7381 gagctgagtt gggattaact aaaaagatag cagtaaatca tctgattagg gattattctt
     7441 gttttttagt caggttttta ctataatggt tattatatca agggagtagc agacggctag
     7501 ccgtgattgt atcgtcaata cggaatttcg gtttccggta caatcttaaa cagcgagact
     7561 tgtttaagaa aataaacagg tctttttatt tgaacaacta aaataaaaag accaaggagg
     7621 tactaatttg tctaaagaac aaagacatga agcgttttac acacaaagtg aagagaccgt
     7681 actggctcaa ttagagacca gtcgcgaagg tcttacgtct gcccaagcaa aagagcgctt
     7741 agcagagtat ggtcgtaatg agcttgatga aggcgaaaaa cgaagtttat ttatgaaatt
     7801 ccttgatcaa tttaaggatt tgatgattat tattttgatt gtggcagccc ttctttcagt
     7861 tcttacagag gggatggaag gtttgacaga cgccattatt atcttggctg ttgttatcct
     7921 aaatgctgct tttggtgttt accaagaagg acaagctgaa gctgctattg aagccttgaa
     7981 atcaatgtca agtccactgg ctcgtattcg ccgtgatggg catgtgactg agatagactc
     8041 taaagaattg gtccctggag atattgtctt gctagaagcg ggagatgttg tccctgctga
     8101 tctgcgtctt ttggaagcta actccttaaa aatcgaagaa gcagcgctta ctggagaatc
     8161 tgtaccggtt gaaaaagact tgtcaacggc tgtttcagaa gatgccagta ttggtgatcg
     8221 cgtcaatatg ggatatcaaa actcaaatgt gacatatggt cgtgggattg gggttatcac
     8281 taacactggt atgtacaccg aggttgggca tattgctggt atgcttgcta atgctgatga
     8341 gacagataca ccattgaagc aaaaccttga caacctttct aagattttga cttatgcgat
     8401 ccttgtgatt gcagcggtga cttttgctgt tggagtcttc ttgcgtggtc aacacccgct
     8461 tgaaggcttg atgacttcag tagcgcttgc cgttgcagct attccagagg gacttcctgc
     8521 gattgttact gttgtgcttt ctcttggaac tcaagtactt gctaaacgta acgccattat
     8581 ccgtaaatta ccagctgttg aaacgctagg atcaactgaa atcattgctt ctgataaaac
     8641 gggtaccttg acaatgaatc aaatgaccgt tgaaaaagtt tataccaacg ggacactcca
     8701 aagttcatca gctgatattg cctttgacaa tacgacactt cgtgtgatga actttgctaa
     8761 tgatactaaa gttgatcctt cagggaagtt aattggtgac ccaacagaaa cagctttggt
     8821 acagtttggg ttagaccaca attttgacgt acgtgaggct atggtggcag aacctcgtgt
     8881 ggcagaactg ccatttgatt ctgaccgtaa gttgatgtca accattcata aacaagctga
     8941 tggcaaatat ttcatcgctg ttaaaggtgc gccagaccaa ttgttgaagc gtgtcacaca
     9001 gattgaagaa aatggacaaa ttcgttctat tacggatgct gataaaaaaa ccattcttga
     9061 taccaataag agtcttgcca aacaagctct tcgtgtcttg atgatggctt acaaatattc
     9121 tgatgctctt ccaacactgg aaacagaaat tgttgaggct aatcttgtct tctctggttt
     9181 ggtagggatg attgaccctg aacgtcctga agcagcacag gctgttaaag tagctaagga
     9241 agctggcatt cgtccaatca tgattactgg tgaccaccaa gatacagcaa aagctattgc
     9301 gaaacgtctt ggtattatcg aagaagatgg cgttgatcat gtctttacag gtgctgaact
     9361 caacgaatta tcagatgaag agttccaaaa agtctttaaa caatactccg tgtatgcccg
     9421 tgtgtcacct gagcataaag ttcgtatcgt taaggcttgg caaaatgaag gcaaagttgt
     9481 tgccatgact ggcgatgggg ttaacgatgc accatctctt aaaacggcag atattggtat
     9541 tggtatggga attacaggta cagaggtttc taagggagct tctgacatgg ttcttgccga
     9601 tgataacttt gcaaccatta tcgttgcggt tgaagaagga cgtaaggtct tctcaaatat
     9661 tcaaaaaaca attcaatatt tactttctgc taacatggca gaagtcttta ccatcttcct
     9721 tgcaaccttg tttggttggg atgtgcttca accagttcac ttgctttgga ttaacttggt
     9781 aactgatacc ctaccagcta ttgctcttgg tgttgaacct gctgagcctg gtgtgatgaa
     9841 acacaaacct cgtggacgta agtcaagctt ctttgatggt ggggtgaagg aagccattct
     9901 ttaccaaggt gccttccaaa ccattttggt gcttggggtt tatggttttg ccttgatgtt
     9961 cccagaacac acaagctacc atgatgtcca tgcagatgcc ttgaccatgg cttatgtgac
    10021 cctcggtttg attcagttgg tacatgccta caacgtgaaa tctgtttacc aatccatctt
    10081 tactgttggg ttgttcaaaa acaaattgtt caactattct attccagtgg cctttgtagc
    10141 attgatggca acagttgttg ttcctggatt taatcaattc ttccatgtga cacacttgac
    10201 gatcacacaa tggttagtgg ttattatcgg aagtctcttg atggttgttc ttgttgaatt
    10261 ggtgaaagct gttcaacgat cacttggtca agatgaaaaa gcaatttaat agacgctaaa
    10321 aggtttgaga taattgtctc aaaccttttt ttataatcgt tacaacgata aggactattg
    10381 gtatgcctga cattaaaaag ttgattcttg ccaattgact tgacagtcaa aaatttgttg
    10441 tttggcttct tgactgtgac cttcaatatc atcgattaaa atcttagtag cctgttcgcc
    10501 ttcttcatag gcgggttgga taatagttgt tagtgttggt gaagaaaatt ttgtccactc
    10561 aatgttatca aatcctacta gtccaatctc tggtatatta aatttaagag acttcatagc
    10621 tgtaaatact tttggaagag cccaacaatt ggggacaaaa accaaactct ttttagtcag
    10681 tgatccttgc aaaaattgag caattgcctc tgaagaagtc tgattttcat caataatcat
    10741 ttcttgatga gtaagatgat tagcttctaa cacatcaatg aagcccgaag cgcgttcaat
    10801 acgagtacta agtaaattgg ggttacccgt gatcatgata aaatgttcat aacctttatc
    10861 gatacattgt tgaatggtat cataaacagc atcataatta ttagttttga cccagttggt
    10921 acgatgctca taaagttgac tatcaaaaaa gacaaccttc ttttttttaa tatcgataat
    10981 gcgagaatac ttcctgaaat tagaggtagg ctgaatgata aagccatcaa ctccgaggtt
    11041 cagcatcttt tcaatgagtt catcttcgcg agaagggtcg tagttgctgt ttccgatgat
    11101 aatttggtaa ccaaattcct gggctttgct ttcaattccc ttaacaattt gattggaaaa
    11161 actattggta atatcaccaa taaccacgcc aatgagttta gtagatttgg cgtttagact
    11221 tctggcagca atgcttggtt tatagttggt agcttcaatc gtgcttttaa tgcgattttt
    11281 agtttcttct gacatcttgt caaatttacc gttcaagtaa aaggaaactg tcgttttgga
    11341 agttttagcc aattcagcaa tatctttgat ggttactttg cgctgcattg catacactcc
    11401 tttaatttag taatggttag tcatattata acataaggac tcgtaaaaga tttagtgttt
    11461 caatcgaata atctcattcg tgatatggtt gataacaacc acctttcctc taattttatg
    11521 accatttagg agaactagtt tttctccttt aattaagtcc tcttggagaa cgcagatact
    11581 gtagtcaaac tgctttcctt ttaaatgcca agcaagagcg gtctcaattg ggttgcgttt
    11641 gcctgtttga agtggtgtta agggagtaac tttggtatcg tcagggacta atagggtact
    11701 ggtgcaaccc ttgtctttaa agggttttcg tttgatgagt ttgtgactag tcaggtattg
    11761 gttgtatttt tttgacaaaa tcgtttcttc gatagtgaaa gggcagtcac tgattagtct
    11821 gaggtcacta aggtgatctg tctttacgtc taagtgatta tcaagaataa attgactgac
    11881 aagacagtgg ttgccttgag cctgtatcgt atcaatgata agaaaaattc ctggtggtaa
    11941 gatgagaatt tgtcggtcat gttggtagtt gttcctatca gagaattgcg tctggtagct
    12001 accatcaata aagtaaatgt gtccattttg tcgaaggtga caataattgg atttggggta
    12061 agaaaggtaa gcccaggagc tatcaatctg ctcaggtaat tgttcttcta agaaggcggt
    12121 agaatgatgg ctagcgcttt ttagggcata gcgtaatggt tcttctttgt aagtgtatcg
    12181 cccagcatca cagaaaagtg gttctccttt ataatagaga cagagactat tttggtcgct
    12241 atgggtatgg gaactaccga tgggcccatt tttgaaaaaa agataataac tttcttgatt
    12301 gatggtaatg tgcccggaat gttcaaagtg atgcgcaaaa gttggtaagg tttggatggg
    12361 taactgttca aaagtgtgga cacctttttc tcctagaagg agaagactat cgatatcaag
    12421 tgtgggaaaa gcagcagctt ttaagtgtgg ttcttcaagg atagtggctg ctagcgttag
    12481 aatatctctg gtatcggtaa aatcactatc tcccaagggg atctgtttgt ggtcaggacc
    12541 agtcattttg aggagataat cactcatggc aagcaaagta ggtctaagct gtggaagata
    12601 atcagggact agagcagtta attccagaag ggctttgagt acttccacat gatacatggt
    12661 tgattgttca aattgactgc cgtcttcgag aatttggagt gcgatttgtt gcgtcaattc
    12721 ttttctagcg aaagctgttg ctgcagcaat atcaaggttg gaaccatagt aggcatcagc
    12781 taataaaatc gcagtggttt gcaagattcc ccaattgctg aggctgtatt tatcaaggta
    12841 gttggcatgg agaaagtgaa gttgtttttc cagggaagct aggatgaggc tttcctcttg
    12901 cttggttaag gcgttaaaaa gattaaggta aatcaaacat ttgacccaag caaaacaacg
    12961 gatgccagta tctaaggttc tagtagctaa ccccttaggg tctaaaggaa tagctgattc
    13021 aatccaattg agaatgaaac ttttggcttt taggagatac cgttcatctc tttcaacaag
    13081 gtagacgagg attaattttt ggagataggt ctgtcgattt aacataaaat tccactcagg
    13141 atcatctgtg atagcctttt gccaagtaat gggatctaag tggtaaggga tgtggcaggg
    13201 ctccatatcc caattatctt caaataaaaa ggtattggtt aagagtaggt cagctatcct
    13261 ttttcgatca gcatagctgt cagcctgata gtctagcagg taattcctgc aaaagtctgg
    13321 attgactgtt tctttaaagc gtgtgaaggc aagagacata ggacatttcc tttccaaaag
    13381 aaaagagacc tcatcatgtg cttaggaact atttccctat gctcataaca ggtctctgtg
    13441 aaccattaag ctaaaatacc taaccagcta ccgataatac cgataagaac agtgaggaga
    13501 accaatttgt aggttgtcca ttttttgttt ttaatgaggt agtacattag aagggtaaag
    13561 agagctggga gaagggcagg agcaatttta tcaagcatcc cttggattgt cacaaatttt
    13621 tgtgctgcat tggccgcatc caccttgcca gcggcaaaag taatgggaac agtaatttta
    13681 acagaagtag ctgctagtcc agcgataacg gtaacgccga caatatttgc catgcgcgac
    13741 acaactgcca tttgttcact taatttatca ataaagcttg tgccgacctt gtagccatag
    13801 agtccagaac cgattttaat agcggttagg ataatattca tggctaggaa gaagaggatt
    13861 ggtcccaaaa ccagaccatc actagctaag gaagctgcaa tcgttgaaaa gagtggcgcc
    13921 aagcaaaatt gtgataagga gtcaccgata ccagctaaag gccccataag tgccattttg
    13981 atgtttcggg tttcttcttc agagcgatta ttttctaaca tgaccaagtg tagactggtg
    14041 atgaaaggaa ggaagtgagg attagtattg taaaactcac agttatcttc taaagcctga
    14101 tacaagccct ttttatcact gccaaaatgt tttttcaagg caggatagat gacattggca
    14161 tatccgatac cttggtaatt actgtaatta aacccatttt gtaggaagaa agctctcaga
    14221 gctgttttga ggtaatcttt cttggttaat ttattagatc cagtcatctt gttggcctcc
    14281 ttggacagtt gttgcatcga cttgtttagg tttgttgtaa aattcattca aggcgaaaat
    14341 gataccaata atagcgatac caatggttgg aatttggagg taggctgcac aaacataacc
    14401 aattagtaca aaaggaatca attctttctt ggccataaca gataagatca tggcaaatcc
    14461 gatagcaggt aacattttac cagcgacagt caatccattg agcaagacag gtgggatata
    14521 atccactaag tgaaggagag tatccattga caaggcacct aataaaccaa gtcctaatcc
    14581 aaggatagca aaagaccaaa tggtcccatt agcagcgaat ttgaagcctc taatattgcc
    14641 tttttgcaat tgttttttag cggtttcagg agcgccagca aaagctgtat aggcgaatgt
    14701 ttgaaggaat tggatggcaa ctgcgattgg tgttgataag gctagtgccg cttctggggt
    14761 gactttacca gcactggtaa tagccatcaa ggtaccaaag ataccagggc cgataggatt
    14821 aggaggaacg gtaccaccgg cacccactcc aaatcccata taagctaatt cggagatagc
    14881 tcccatgcta agtgcagttg gcaagtcacc taagataatc ccgacaccaa aagacagaat
    14941 aatacaacgg ttggtgtaga tgccaagtaa cattccgctg aaacaaaagg ctgtccaaag
    15001 accaattaaa agtgcctgta acaaattgat atccatatca atctccttta ttcattaaat
    15061 ataatctaag atgtcaacgt cagaggcgct attgccagct ggagttgttt tggtgttaaa
    15121 aaccacttgg tggtcatggg ctaggcaacg aatagcagac ttgtctgttt ctcccagcga
    15181 aataaactgg gtaatcgcaa ccttatcatc agttttatga atattaccga tattgatttc
    15241 tgtgatggga acaccccctt caactaggcg tttggcatct tgcaaatctt tgaccacgat
    15301 gaagatactt tgagcaggac ttgctttatg aatgatgtca atcacttttt gaatggagaa
    15361 aaaacgaatg gcaatactgg atgggataac tgttttcatg agggattgtt gaatcttatc
    15421 ttcagaaacc gcatcgttag cgacgataac agtgttgcag ttgaggtatt tgacccataa
    15481 ttgcccctgt ccgtgaatca agcgctcatc aactcgcgtc atgataatgt ttggttgtgt
    15541 cataaaatct cctttttaaa tgtaggtatc ggtgtttgtt accagtaagg gttccagtct
    15601 ttgtagaaac gaagcagagc ttcaagatag taatagtctc cccagatatt tccctcgtca
    15661 accccttttc cagagtgcca agaatagact ccgtgaagta gtagaggagc gccaggattg
    15721 agatctttgt tagcataatc cttaatcaag gctcttagca tgctgtgcat ggcagcttca
    15781 tatgtttttt tatcaggatc atgatctggt aaggttttta acatttcatg aataccacac
    15841 acagcaatgg ctgttgctga actatcacga gactgctcgc tatcatctct aaaaattaaa
    15901 tcccagtagg acacctggtc tttaggaaga cggttcaaga aataatgggt catgcccttg
    15961 aagagttgaa tgagttcagg ttcttttagg aaacgatagg tcaaaggaat accataaatg
    16021 ccccaagctt gccctctggc ccaagcagaa tcatcgctat aaccttgtcg ggtgacccct
    16081 ttaacaggat cgcctgtttc tggatcaaag tagaaggtgt ggtaagcaga ggcgtcatct
    16141 cggatgacat gattggctga ggcgtagaaa tgattgatcg ccatgtcacg gtaacggttg
    16201 tctccagttt cttggctagc aaaaaagagt aattggatgt ttaggagaca atcaatgatt
    16261 aaacggtaat cttctttttt acccagcacc ccccaagctt gaataaagcc acctttatcc
    16321 tgatagcgtt ggactaattt gtcagctgct ttcaaagcag cttctctagc ctcagaagtt
    16381 tttaaaagtt tccactcagc catgcaagaa ggggtgtaaa gaaagccaag gtcatggtga
    16441 tctagctcaa tgtctcttgt tactcgatct aggaaagaaa ggtcatttgc ttgagccaga
    16501 gctttaatgg catcatctcc actgtattcg taagctaacc agaggcagcc agtccaaaag
    16561 gcattggtcc attccgtgtt gtccataatg gtgtattggt tatctttggt agctggcgtt
    16621 ggaaaatctt ctttgaagta gtccatgtta agccgaactt gtttgagggc taagtcaagg
    16681 gcctgagtaa tgtcttcttg gcttaggaaa tcttctttgg taaatcgttc aggctgcttg
    16741 ataggttcaa gagcaatggt ttttaaagat cgtgtcatta aatgcctcct aactcatcgt
    16801 ctgtcgtacc gtcttcttgc tgagaaagag tcttccagtc aacaatgcct tctttagaac
    16861 atgttataag tcctgatact aagtcgtcaa aagaagctgc tgtttgtctt gcaaaactag
    16921 cttcaatcag catggctaag ttaaggccag aaagaacatt acacgtcgtg tttgaaagag
    16981 attccattaa ggttgcagcg actttaaaag gggtacctcc tagaaggtca caaagaacta
    17041 aggtttcctc ttctgggatt aaagcacgag ataattggtc ctgcacatca gcggcggtca
    17101 tctcagcagt aaaatcaatt gcagttacct tctcttgttg tcctgcaatt aactctaggg
    17161 atgagacaat cccacttgca aagtgtccat gtcccataac aataatagca atcataaata
    17221 gatctccttt agtttaccgg tttacttaaa aacattgtag cgctttcaaa attctttgtc
    17281 aatacttttt taaaaagatt tttgaaaaag aaaaagtgag cagttgtgct aaaaaagaat
    17341 caaaaatggt cttttttgtc actatttaat gtagaaaagt cttaatagct attaagtata
    17401 ggacaagact aaacaagaat gacagtttgg ataagagtac tcttttaaat ttttgaaccg
    17461 ttttcattaa aatgattgac aaaactagtt tactttgtta tagtcttggt aaacaggttt
    17521 acttaatcta ataacaaaaa ggagaatcct atggaaaata tgttttcgtt acaaggtaag
    17581 attgccttga ttaccggagc atcctacggt attggttttg aaattgccaa agcctatgct
    17641 caagcgggtg caactattgt gtttaacgac atcaaacaag agttagttga taaggggttg
    17701 actgcctatc gagagttagg gatagaagcg catggctatg tttgtgacgt gactgatgaa
    17761 gctggtatcc aacagatggt tagtcaaatt gaagatgaag taggtgttat tgatattctg
    17821 gtcaacaatg caggtattat tagacgtacg ccgatgcttg aaatggccgc agaagatttt
    17881 cgtcaagtca ttgatattga tttaaatgca ccttttattg tgtcaaaagc agttttgcca
    17941 tcgatgattg caaaaggaca tggtaaaatt ataaatatct gttctatgat gagtgaattg
    18001 ggtcgtgaaa cagttagtgc ctacgcggcg gctaaaggtg gcttgaaaat gttaaccaaa
    18061 aatatagcct ctgagtttgg agaagccaac attcaatgta atgggattgg tcctggctac
    18121 attgcgacac cacaaacagc tccgttgaga gagcgacaag cagatggtag ccgtcatcct
    18181 tttgatcaat ttatcattgc taaaacacca gcagcacgtt ggggggcaac agaagactta
    18241 gctggtccag ctgtttttct agctagcgat gccagtaatt ttgtgaacgg ccatatcctt
    18301 tatgtcgacg gtggcatttt agcttatatt ggaaaacaac cttaatcaca cactagaaag
    18361 agattttata tgaaaattgc attaattaat gaaaatagcc aagcggctaa aaatggtatt
    18421 atttacgatg cccttacctc agtgacagat aaatacggct atcaagtctt taactatggc
    18481 atgtatggca cagaaggcga aagtcagttg acctatgttc aaaatggact cttagcttct
    18541 attttattga ccactaaagc ggccgatttt gtggtgactg gttgtggaac aggtgtggga
    18601 gctatgttgg ccttgaacag tttcccaggg gttacctgtg gttttgcgag tgagccaaca
    18661 gaagcttatc tcttttctca aatcaatggt ggtaatgcct tgtccattcc ttttgccaaa
    18721 ggttttggtt ggggagcaga gttgaatttg accttaatat ttgaacgcct ctttgcagaa
    18781 ccaatgggtg gcggttaccc taaagagcga gctattcctg aacagcggaa tgcacgtatt
    18841 ttaagtgatt tgaaaaaaat tacttacaga gatttgttgg caattgtcaa agacatcgac
    18901 caagatttcc tcaaagaaac gatttctggc gctcatttta aagagtactt ctttgccaat
    18961 gcggagccgt cagaattagt cgcttatttg aaatcagtac ttgaacagta attccatttt
    19021 gacgaggaaa ggaggtcaca tgtctaagtt attattggtt ggtgaaccgc tgattcgcgt
    19081 tagccccaat cagtttcagc ctttgaccaa tgcctgcgac gctcagcttt ttttcggcgg
    19141 ttcagaagtt aatattgcaa gaactctagg cggttttggc ttagaagtaa ggctatttac
    19201 ggccctacca gataatcctg ttggtcacgc ttttcatcag tttttgaagc aaatcggtgt
    19261 ggatatgacc ttgacggctt ggcaaggcaa ccgtgttggg ttgtattacc ttgaaaatgg
    19321 ctttggctgt cgggctagtc aggtttatta tgaccgctgt ggctctagct tttcggcctt
    19381 agataaggat agtcttgatt tagcggccat ttttgaaggc attcgtcact ttcattttag
    19441 tgggatcagt ttggcgctgg gcaaaaaaac tcaggatctg attgagatac tagcgagaga
    19501 agctaggaaa aggcaagttt gtgtttcttt tgatcttaac tttagatcta gtatgattgc
    19561 ggcagctgat gctaaacgac tcttttctca ctttgctcaa tacgcggata ttatttttgg
    19621 catggaacct ttgctgttag acagtgacga ttttgacatg tttgatagga ataaggcaga
    19681 tgctacgatg attagagaac gtctggcagg actttatcag cgctatcagt tacaagctat
    19741 ttaccatacg gagcgttcaa atgatgccca aggcagtaat cgtttcaagg cttatgccta
    19801 tgatgggcag ttttacgaat cctgtgaagt gacgactcca gtcttacaac gggttggaag
    19861 tggagatgct tttgtggcgg gtttacttta tcagttgtta gaaggtaacg aaaagcagcg
    19921 caaccttgat tttgctgtgg caacagctag cctaaaatgt acagtagctg aagatcagct
    19981 ctatcacagc gtccaacaag tagaagcagt cttagctaat caacgagatg tccagaggtg
    20041 atgatatggg aaaaatagaa atcttaacca aacttaaggc taatcggctt gtcctggttg
    20101 tacgaggaga gtctagtgag gaagctttag cttgcagcct ggccagtatt gaaggtggca
    20161 ttaagacaat tgaagtcacc tatactaacc cctttgctag tgaggttatc ggtcaattag
    20221 ctgaacgctt caaagaagat cctgaggtat tgataggtgc tgggacagtt ttggatgatg
    20281 tcactgcccg ccaagctatt ttagcaggag cacagtttat tgttggtcct aatttcaatc
    20341 gagcagtggc tttgatttgt catcgttata gcatacctta tttaccaggt tgtatgacgg
    20401 ttaatgaagt ggttacagca ttagaatcag gggttgatat ggtcaaaatt tttcctggtt
    20461 ctactgtagg gatatccttt attcgggcaa tcaaatctcc tttgccacaa gtagaggtta
    20521 tggttacagg cggagtttct tcagataatc tcaaagactg gctagctgct ggagtagatg
    20581 ttctaggcat aggaggcgag tttaatcagt tagcgagcca aaaacaatat aacctaatca
    20641 ctaagaaagc cgctcattat atcaaaagtt tgcgacaata atctaaaaaa cgtttttacc
    20701 ttggctttag tgctagtaaa aacgtttttt tatcattcat tcaattaata tgcttctgct
    20761 tatgtttttc cagatagtat agatataaga gcagctaatt taacaagatg agcctgtcgt
    20821 ttgatatata ggatataaac tttttatgat caaacaaaag taataccttt tgaattcgtt
    20881 agtattgacc tgatctaaag tgatatcact tagaatggac tagctgtaca gcttttacag
    20941 caacttatgc taaaatagaa aaaaaggaga aatgttgatg attaaaggaa ttatttttga
    21001 tatggacggt gttttatttg atacagaacc tttttatctg aggcgacgag aagatttttt
    21061 taagacaaag ggaattccca ttgatcactt gaactctaaa gattttattg ggggcaatct
    21121 ccaagaatta tggaaagagt tgttaggtaa aaatagggat gatgctatcg ttaaggcaat
    21181 tacaactgac tatgacgctt acaaacaagc gcataagcct ccttatcaaa aactgttgat
    21241 tacagaagtg aactcttgtc ttgaacagtt gaaaaaacaa ggtatcaaac tggctgtggc
    21301 atcaaactcg aagcgtcagg atgttttgtt ggcgttggag acaacgcaaa taaaagatta
    21361 ttttgaaata atcctagcgc gtgaagatgt ttctagaggc aaaccttatc cagatattta
    21421 taataaagca gtacaaaaac taggattaca aaaaaaacaa ctgcttgtag tagaagacag
    21481 ccaaaaaggc attgctgccg ctaaagcagc caatctgaca gtttttgcca ttaccgacta
    21541 ccgatatggc attgatcaga gtcaagctga tcacaagata gatcatttag gacaactgtg
    21601 tgtaaaaatc ggttgttttg gatcgtgaag taacgcaact aactgatcat tgatgatact
    21661 tcaagacact taagaatacg tctaggactt tctacagacc aataacaaga atacgtttat
    21721 gtgtttttac tgtttttcag ctacctattt acaatatgac actgaaaaga gtactatgtt
    21781 taagttatta tcaaaaaaac cgtcgcataa gatcacctag aaaaggatta tgatttttgt
    21841 gatatggatg tgatcattag tcgtcgacca tctttatgtg gcaggaggta tgtttaaccg
    21901 tggtcattat ttggatttgt ttttagattg gctagtgagt aaatatagaa ggatcataat
    21961 actgctttga caaaggcagt atctgagtcc ataagttgca cggataatgt gactcggttt
    22021 tggttaggta taataatatt tggaagtgtt atgctgcttg tcttcgtagg tccattgatt
    22081 atagtcagac ttactttaga gctgagctga ctgtctagac aagacgtgat ggagatgtga
    22141 tttctgacca agtagaggta accagaaaag ggacttttac gatgtaattg aatttacttg
    22201 ttgcattctt gtgcatgtta agagagaaaa cccaaataaa tcaagaagta aaatggttat
    22261 gtttgattag aattgtcctt ctttttcctt gaagtcttaa cttattttga ttatgatagt
    22321 agtatgacta ttaaggcaga aattaaggca ctcgccaaag aaattggtat ctctaaaatt
    22381 ggttttacga cggcagataa ctttgattat ttggaaaagt cattgcgtgc ttctgtggaa
    22441 gaggggcgca attcaggatt tgaacataaa gtcatagagg atcgtatctc ccctgaaagg
    22501 cttttagaat cggctaaaac gattatttca attggcgttg cttatcctca caaacttcct
    22561 cagcaacctc aaaaaacacc ttataaacgt ggcaaaatta cacctagttc gtgggggctt
    22621 gattatcatt atgtggtcgg cgaaaagtta gacagactat caaaaggcat tgaagagctg
    22681 tgtcgagatt ttcctttgca acaaaaagca atggtcgata ctggagcttt agttgatact
    22741 gcagttgccc aaagagcggg tattggtttt ataggaaaaa atggtctagt tatttctaaa
    22801 gaatatggct cttatatgtt tttgggagaa ttaattacca atttagagat cgagccagac
    22861 aagcctgtcg attatgattg tggtgactgt cgtcgttgtc tagatgcctg tccaacttct
    22921 tgtttaattg gtgatggctc aatgaatgcc aagcgttgtc tatcatttca aacccaagat
    22981 aagggaatga tggacataga gtttcgaaaa aagattaaaa cagttatcta tggttgtgat
    23041 atttgccaaa tttgctgtcc ttataacaag ggtataaaca attcaccagc tacagagatt
    23101 gatcctgagt tggctcaacc agaattaata ccatttttga gtttatcaaa tggacaattt
    23161 aaagaaaaat ttggtatgat tgctggaagt tggcgaggta aaaatatttt acagcgtaat
    23221 gccattattg cgctagcaaa tgctcatgat aaaaccgcag tggtcaaatt aatagagatt
    23281 attgataaaa ataataaccc tattcatact gcaacagcta tatgggcatt gggagaaatt
    23341 gtcaaaaaac caaacgatga gatgctggcg tttatgagtc atttaacctt aaaagatgaa
    23401 gatagccaaa aagagttgga attaatccgt cgtaaatggc aagtttaagc cttttatggt
    23461 atttttaaga accttatgat aaaataaaac agattaacaa agattggaga aatctcatgg
    23521 aagtggctga aattcgccaa aaaatagtag aaaataaaga gaagttgact agcttcagga
    23581 ggtctctttg acttagatcg tttggaagag gagattgctc ttcttgaaaa tcacatgact
    23641 gagccagact tttggaatga caatattgca gcgcaaaaga catctcaaga actaaatgag
    23701 ttaaaaggta agtatgatac tttccataat atgcaagaat tatctgacga aacagaactc
    23761 ttacttgaga tgcttgacga agatgattct ttgaaagaag aattagaaga aaatctaatg
    23821 cagctagata agataatggg tgcttatgaa atgacgcttc tcttatctga accctatgac
    23881 cacaataatg ctatcttaga aatccatcct ggttcaggag gaactgaagc gcaagattgg
    23941 ggagatttac tcttacgaat gtatacccgt tttggtaatg ctaatggttt caaagtagaa
    24001 gtattggatt atcaagcagg agatgaagct ggtattaaat cggttaccct ctcttttgaa
    24061 ggccccaatg cttacggttt gttgaaatca gaaatgggag ttcatcgcct cgttcgtata
    24121 tcaccttttg attcagctaa acgtcgtcat acttcatttg cttcagttga agtgatgcca
    24181 gagttagatg atacgattga agtagaagta cgtgatgatg acattaaaat ggatactttc
    24241 cgttccggag gagctggtgg tcagaacgtc aataaagtat caacaggtgt tcgtttgacg
    24301 catattccaa ctggaattgt ggtatcgtct accgttgacc gtactcaata tggaaaccgc
    24361 gatcgcgcta tgaagatgtt gcaggctaag ctatatcagt tagaacaaga aaagaaagca
    24421 caagaagtag atgctctcaa gggtgataaa aaagaaatca cttggggaag tcagattcgt
    24481 tcttatgttt tcacccctta tacgatggtg aaggatcatc gtactaactt tgagcttgct
    24541 caggtagata aggttatgga tggagaaatc aatggcttta ttgatgccta ccttaagtgg
    24601 cgcattgaag actaaaaata ataaaggaga aacatggcac taatagaaat gtctggtgtt
    24661 actaaaaaat accgccgctc aacgaccgcc ctcagagacg tcaatgtttc tgttaaccaa
    24721 ggtgagtttg tttatctcgt aggcccatca ggtgctggta aatcaacttt tatcaaactc
    24781 ctttaccgtg aagaacaact gacaactggt aagctatatg tgggtgaatt caatttaact
    24841 aagctaaaag cacgtgatgt tccgattctt cgtcgtcaca tcggagtagt ttttcaagat
    24901 tacaaactgc taccaagaaa aacagtcttt gaaaatgtag cttacgccat ggaagttatt
    24961 ggtgaaaagc gccgccacat taaaaaacgc gtgccagagg tactcgattt agttggcttg
    25021 aaacataaga tgcgttcttt tccaagtcag ctatcaggag gggagcagca acgtgtggcc
    25081 attgcgcgtg cgattgttaa caaccctaaa ttattgattg cagatgaacc gacagggaat
    25141 ttagatcctg agatttcatg ggaaattatg cagttacttg aacgtattaa tgttcaggga
    25201 acaactatct taatggcgac acacaacagt catattgtga atacatttcg tcatcgtgtt
    25261 gttgctattg aagatggtcg catagtacgt gatgaagaaa aaggagatta tggttacgat
    25321 gattagatac tttttccgtc atatttggga atccattaaa aatcttaaac gcaacttttg
    25381 gatgacattt gcttcagtta gtatggtggc tgttacattg actttagttg gtgtttttgc
    25441 ggcgacattg ttgaatatac agcgtgttgc ttcgggtgtt gaaaataatg tccatatcaa
    25501 tacctactta caagttgatt caactgatgc tgcaaaagtt attcaaaata ctgccggtga
    25561 acctgttaat aacgataact accacagtgt ttacgacaaa attgctcaga taaaaggtgt
    25621 caaaaagatt acattttcta gcaaggatga acaattgaaa aaattgcaag aaaccttagg
    25681 tgatgtttgg aatatgtatg accaagacac taatccgctc caagatatct atcttattga
    25741 gacccagacg cctaaacaag ttaaggcgat cactaaaaag atcagaacga ttgaaggcgt
    25801 agaagccgca gattatggag ggattaactc cgataaacta tttaagtttt caacattaat
    25861 tcaaacttgg gggctgatcg gaacagcaat gctattattt gtagctgtct ttctcatttc
    25921 aaacactatt cgtatgacta ttatgtctcg taaacgcgac attgaaatta tgcggttagt
    25981 tggtgctaaa aattcttata ttcgagggcc tttctttttt gaaggggctt gggttggctt
    26041 gttaggagct gttttaccat ctcttctgat ttattatgga tatgatcttg tttataagca
    26101 ttttgcacaa gaattacaac gtaataatct ctcgatgtat ccgcttgatc cttatgtata
    26161 ttacctgatt ggtgctttgt ttgtcatagg tattatgatt ggttcgcttg gttcagtgct
    26221 ttctatgaga cgttatttaa aattctaaaa aaagcgctgc tgacgaaacg tagcgacccc
    26281 caaaagttgg acctcttatg ttattccaag gacttcgttt tgtattgcac aggactggtc
    26341 cttttcattt tgttttgatt catttgttta tttgtaatag gcaatatagt ttaaaatagc
    26401 agtttctaag gtttcaagag aagaaaagca ccccaaaagt tagatgtttg atgtatctaa
    26461 cttttggggt gtcattcaaa atttagtggc tcttttttag taaaatacta tgatttcagt
    26521 tttaggataa cctcaaacag tatctaaaat agctatgtca atgaaaaaag gggttagcat
    26581 ttttttcgtg acaaatggta gtagaaggac catgcccagg ataaactcgg taatgattag
    26641 gtaaggtgaa tagttcttgg cgaataccag taatgaggtc ctcaaagtta ctggtaggta
    26701 agtcagtacg accgatagtt tcacgaaata gagcatcgcc agtaacgact aattcatctg
    26761 agtggaaaac aaatgagact cctccccaag aatgaccagg tgttggtaaa actgtgaatt
    26821 caaaaccatt tagttgatag ggttgcttta atttaaaaaa gttctctgcc ggtcttgcta
    26881 taacattaat gatatcatca tgacggccta agccagataa attatcatct ggggaagata
    26941 gccaagcggc ttctttttct gaaacataaa caggtggatg atcaaaagca tctctgacca
    27001 aatctaaact aaaaatatga tcatagtgag tatgcgttaa gaggatagcc actaaaggtt
    27061 tttcaaagga tttaatttta gaaatgattt cttggccgtt acttcctgga tcaatgagga
    27121 taacagcttg atcattaacg aggtaataag tattttcacc agcaatgtgg tttattgttt
    27181 tatagatttt cataaggata gtgtaccaaa aaatcaaggc tttgttaaaa aaagagtagc
    27241 ggaaaataaa tggcaattag tttcagaaaa tatgagatct cacagcaatt tcttgacacc
    27301 gttttcataa aggtgtatca taaaagtaat caataagcca agcctaaagc tgaacttagt
    27361 ttaagaacac tgactttttg agagcaacct aatcggttga ctaaaaaata tgaggtggaa
    27421 gatatgtcaa aagttgctat tgttactggt gctggtcaag gaattggatt tgctatcgcg
    27481 aaacgtcttc atgcagacgg ctttaaaata ggcattttag actataatga agagactgct
    27541 caggctgcgg ttgataaact atcacctgag gatgctgttg cagttgtagc agatgtttca
    27601 aaacgtgacc aagtttttga tgctttccaa aaagttgtag atacttttgg tgatttgaat
    27661 gttgttgtta acaatgcagg tgttgcccca acaacccctc ttgacacgat tactgaagag
    27721 cagtttgaaa aggcttttgc aatcaatgtc ggaggaacga tttggggaag ccaagcagct
    27781 caaaaacatt ttagagaatt aggtcatggc ggaaaaatta taaatgcaac gtcacaagca
    27841 ggatgtgaag ggaatcctaa tttgactgtt tatggtggta caaaatttgc agttcgtggt
    27901 attacacaga ctttggcaaa ggatttggca tcagaaggaa tcacagtcaa tgcttacgca
    27961 ccaggtattg ttaaaacacc tatgatgttt gatattgccc atgaagttgg taaaaatgca
    28021 ggcaaagatg atgaatgggg tatggagcaa tttgcaaaag atatcacttt gaaacgcttg
    28081 tctgaaccag aagatgttgc taatgcagta ggcttcttag cgggagatga ttcaaattat
    28141 atcactggac aaacaatagt tgtcgatggt ggtatggtat tccattaaaa atgattaata
    28201 ctgacactgt gagtgaaact cacagtgttt tttatatttc ttaaaaaatt atcctatctt
    28261 ggttattgga gtgatggcac ctttgagata tagtcatgtt ttgttttata gatatagcgt
    28321 gctataatag acttactatg acccagaaaa aacttagaaa atatgcagta gttgacttgg
    28381 aggctactgg agcaggtccc aatgcttcta ttattcaggt tgggattgtt attatccaag
    28441 gaaataaaat tattgatagt tatgaaacag atgttaatcc tcatgaatct ttggatgagc
    28501 atattgttca tttgacaggt attacggata agcagttggc taaagctccg gattttggtc
    28561 aagtggcgca tcacatttat caattgattg aagattgtat ttttgttgcc cacaatgtaa
    28621 agttcgatgc aaatttattg gcagaagctc tttttttaga aggatatgag ttaacaatac
    28681 cacgtgttga tactgttgaa ttagcccaac tatttttccc tcgctttgaa aagtataacc
    28741 ttagtcacct atctaggcag ctcaatattg atttggcaga agctcatact gctattgcag
    28801 atgcaagagc tacagctata ctgtttttaa gacttttaca aaaaattgag agccttccaa
    28861 ttgagtgctt agaaagctta ttagtctatt cagatagcct gctatttgaa acagcaatgg
    28921 tcattcaaga aggattagcc aaagccaaac cttatgatcc caacaaatac attaaaatca
    28981 gacagattct cttaccaaag ggctcaaaag ctctcaagcc ttatcaaata tcaaaaagct
    29041 tccctattaa tatggcacta ttaggtctgg aagaaaggcc taaacagact caatttgctc
    29101 agttaattga cgaagattac catcagggag tagctagttt tattgaagct cagacaggta
    29161 ttggaaaaac ctacggctac ctgctacccc ttttggcaaa agaagatcaa aaccaaatca
    29221 ttgttagtgt gccaaccaaa cttcttcaag accaattaat ggctggtgaa gtagctgcta
    29281 ttcaagaaca atttcacatc gcctgccata gtttaaaagg gcctgccaat tacctaaagc
    29341 tagatagctt tgcagatagt ttggaccaaa atgaccagaa ccgtttggtg aatcgttata
    29401 aaatgcaatt attggtttgg ctcttagaaa ctaagacagg agaccttgac gaaatcaaac
    29461 aaaagcagcg ctttgccgct tattttgagc agcttaagca cgatggagac attaagcagt
    29521 cttctgaatt ttacgattat gatttttgga gagttagtta tgaaaaagcc aaaacagccc
    29581 gtctcctgat taccaaccat gcttattttt tacaccgtgt tcaagatgac aaggacttta
    29641 ctagaaacaa ggtcttggtc tttgatgagg cccaaaagct gatgctccaa ttagatcaat
    29701 tatcacgtca tcagcttaac ctgacggttt ttttacaaac aatacaggcc aagttaagca
    29761 accctttacc tcttttagaa aaacgcttat tggaaagctt gtcgtttgaa ctgggacaag
    29821 tgtcaagtga ttactatcaa aataaagagc accagcttgc tcatgattgg tctcgtatag
    29881 ctggctacgc caaagaatta acaggagcag attatcaaga gttacaagcc ttttttgcta
    29941 cctcagatgg tgactactgg cttagtagcg aaaagcaaga ggagaagcga gtgacttatc
    30001 taaacagtgc tagtaaggca tttattcatt tccaacagct cttaccagaa acggtgaaaa
    30061 cttattttgt ttctgccact ttaaccatca gctcagaagt aaccttggca gacctattag
    30121 gttttgaaga gtatctctat catgtcattg aaaaggataa aaagcaagac cagttggtgc
    30181 ttgttgatca agaggcgcct atcgtgacag aagtcagtga ccaaatctat gtggaagcaa
    30241 ttgcaaaacg aatcgaaagc ttgaagcaag agggttatcc tattttagtg ctttttaatt
    30301 ctaaaaaaca cttgctgttg gtttcagact atctagacca atggcaggtg tctcacttag
    30361 cgcaggaaaa gaatggaaca gcttacaata ttaaaaaacg gtttgatcaa ggagagcaaa
    30421 ctattttgct tggtttaggt tctttttggg aaggagttga ttttattcaa gcggatcgta
    30481 tgattaccct tatcgcacga ttgccctttg ataacccaga ggatttcttt gttaagaaaa
    30541 tgagtcatta tctattggaa aaaggtaaaa atcctttcag agattacttc ttgccaatga
    30601 ctattttgcg attaaaacag gctattggtc gcacgatgcg tcgacaagat caaaagtcag
    30661 tggttattat tttggatcgt cgtctcctta caaagtccta tggacaagtt attttggaag
    30721 gtctcggtca ggaatttttg atttctcaac aaaattttca cgattgtcta gtagaaacgg
    30781 actgttttct gatataatag aaaggatcta ttatatcaga aaaattttta atggcgttaa
    30841 gcacaatcaa ctaacattta aattagtttg aacttttatt atgctctttt agacaactgt
    30901 tcacatgttt tcgaattgtt tttttgataa ggacaataaa tgaacaaatt tttggtttta
    30961 gtaaacccaa ttactgttct tttcattagt gtcagttgct atcaaaacag cttgtcatag
    31021 ttcgtgcgat cagtagcgag tattggtaaa actgaaaccg tagattatga aaaaatgatc
    31081 tgttgatcat taattaatct gaagataaga agtcgataaa aaggagatac gatgcccaaa
    31141 ctatcaaagc gagttttaga aatgaaagag agtgttactc tggctgcagg tgctagagct
    31201 aaggctttga aagcgcaggg ccgcgatgta ctgaatttaa ctttaggaga accagatttt
    31261 tttacacctg agcacattca agacaaggcg attgaatcta ttcaaaatgg tacggctagc
    31321 ttttatacaa atgcttctgg gcttccagaa ttaaaagctg cgattgccac atacctgaaa
    31381 aatcagtatg ggtatcactt gtctcctgat cagattgtgg caggaacagg tgccaagttc
    31441 atcctttatg ccttttttat ggctgtttta aatcctggtg accaagttct cattccaaca
    31501 ccatattggg tatcttattc tgaccaagta aaaatggcag aaggtcagcc gatcttcgtt
    31561 caaggactag aagaaaatca attcaaggta actgttgacc agctggaaag agcaaggaca
    31621 agtaagacta aagttgtcct tatcaattct ccttccaatc caacaggcat gatttatggt
    31681 gctgaggaat taagggccat tggagaatgg gcggtgcaca acgatattct tattctggca
    31741 gatgatattt acgggtcctt agtctataac ggcaatcagt ttgttcctat ttcaacactc
    31801 tcagaggcga ttcgtcgtca aaccattacg gtcaatggcg tggctaaaag ttatgccatg
    31861 acaggctggc gggttggttt tgcagcaggt gaaccagaga tcatttcggc aatgagtaag
    31921 atcatcgggc agactacctc taacctgaca actgtttcac aatatgctgc tatcgaggct
    31981 ttctgtggta gtcagtcatc acttgaagag atgcgactag catttgaaga gcgccttaat
    32041 atcacttatc cattgttgtg tcaggtccct gggtttgagg ttgttaaacc acaaggagct
    32101 ttttacttct ttccaaacgt taagaaagcc atggaaatga caggtttttc cgatgtgaca
    32161 agctttgcta atgctatttt agaggaagtc ggattagctg ttgtgagtgg agcaggcttt
    32221 ggcgcaccgg aaaatgttcg tctgagttat gctacagata tcgaaaccct taaagaagct
    32281 attcgtagac tgcatgtctt tatggaaagt aatgaaatta attaaataaa aatagagaga
    32341 aacttatgtc aaaaaaactt atttcaattg ttaatgttaa agattatgtt ggtcaagaag
    32401 ttactattgg tgcttgggtt gctaacaaat caggtaaagg taagattgcg tttgtacagt
    32461 tacgcgatgg ttctgctttt ttccaaggtg tcgcttttaa accaaacttc attgaaaaat
    32521 atggtgaaga atcaggtctt gaaaaatttg acgttattaa acgtctcaac caagaaacat
    32581 ctgtttatgt aacagggatt gttaaagagg atgagcgttc taaatttggc tatgaacttg
    32641 atattactga ccttgaaatc attggagagt cacatgaata tcctgtaact cctaaagagc
    32701 atgggacaga cttcttgatg gacaatcgtc atctttggtt gcgttctcgt aaacaaatgg
    32761 ctgttatgca aattcgtaac gctattattt atgcaactta tgaattcttt gaccaaaatg
    32821 gttttatcaa atttgatagc ccaattttat cagaaaatgc agcagaagat tcaacagagt
    32881 tattcgaaac agactatttt gggaaaccag catttcttag ccaatctggt caattatacc
    32941 ttgaagctgg agcaatggct ctaggccgag ttttcgactt tggtccagtc tttcgtgctg
    33001 aaaaatctaa aacacgtcgc catttaacag aattttggat gatggatgct gagtattctt
    33061 tcttgtcaca tgaggaatca cttgaccttc aagaagctta tgttaaagca ttgatccaag
    33121 gcgttctaga tcgtgcgcct caagcacttg atattttaga acgtgatgtt gaggctctca
    33181 aacgttatat cacagagcca ttcaagcgtg tttcttatga tgatgctatt acacttcttc
    33241 aagagcatga agcagatgaa gatacagatt atgaacattt agagcatggt gatgattttg
    33301 gttccccaca tgaaacttgg atttctaatt attttggagt accgacattt gtagtgaatt
    33361 acccagcaag ctttaaagca ttttatatga aaccagttcc tggaaatcca gaacgcgttc
    33421 tttgtgctga tcttttagct ccagaaggtt atggagagat cattggcggc tcaatgcgtg
    33481 aagacaacta cgatgctctt gtggctaaaa tggatgaact aggtatggat aaatcagaat
    33541 atgactttta ccttgacctt cgtaaatatg gctctgttcc tcatggcggt tttggtatag
    33601 gtattgaacg tatggtaact tttgttgctg gtaccaaaca tattcgcgaa gctattccat
    33661 tcccacgtat gttacatcgg attagaccct aataatacaa aaagttcatg tcatctatga
    33721 actttttgta ttggtaagaa gtgagtgtgt tataaaaaca tcaatatgtc ctaaaggaga
    33781 gataagaaaa aggagagata agaaatagta gagtttgaac ctacatcctt tgtgaagata
    33841 aattttggaa gtttagtaga tcagttagca gataagacaa tatagccttg ctcaagggat
    33901 attttataga caagtatttg gactacgatt atcaaataga cactctcatt tgatactaaa
    33961 aaggtctcgt ctattcatat aataggagag ctacgggagt tattattaaa attagctgat
    34021 ttttacagtt caaaatgtgt taccgctttt tcacttctta gctttcttat gtatgtggta
    34081 taatgaaggt ggacggttcg atagagaaag ggaaattgta aatgtcagac aaacacatta
    34141 atttagttat tgtgacagga atgagcggcg ctggaaaaac agttgccatt cagtctttcg
    34201 aggatctagg ctactttacc attgataata tgcccccagc cttggttcca aaatttttag
    34261 aattaattga acaaaccaat gaaaatcgta gggtggcttt ggttgtcgat atgagaagtc
    34321 gtttgttttt caaggaaatt aattctacct tagatagtat tgagagcaat cctagcattg
    34381 attttcggat tctttttttg gatgcaacgg atggagaatt ggtgtcacgc tataaagaaa
    34441 ccagacggag ccaccctttg gctgcggacg gtcgtgtgct tgatggtatt cgattggaaa
    34501 gagaactcct atctcctttg aaaagcatga gccaacatgt ggtggataca acaaaattga
    34561 cccctagaca attgcgtaaa accatttcag accagttttc tgaagggtct aatcaagcct
    34621 ctttgcgtat tgaagtgatg agttttgggt tcaaatatgg tcttcctttg gatgcggatt
    34681 tggtttttga tgtgcgtttt ctacccaatc cttattatca ggtagagctt cgtgaaaaaa
    34741 caggactaga tgaggacgtt tttaattatg tgatgtctca cccagaatca gaggtgtttt
    34801 acaagcattt gttaaacctt attgtcccta tcttaccggc ttaccaaaaa gaagggaagt
    34861 ctgtcttgac ggtggctatt ggctgcacag gaggccaaca ccgcagcgtt gcctttgccc
    34921 attgcttggc agaaagtctg gcaacagatt ggtcggttaa tgaaagccat cgtgatcaaa
    34981 atcgtcgtaa ggaaacggtg aatcgttcat gaaaaatcct aaaatgactg ttataggtgg
    35041 gggtactggc atctccatta tcctaaaaag ccttcgtaat gaagcagttg atattactgc
    35101 tgtggtcact gttgcagatg atggtggttc ctcaggagaa cttcgtaatg ccatgcaatt
    35161 agccccgcca ggagacttac ggaatgtctt gttagcgatg agtgacatgc caaaatttta
    35221 tgagcgggtt ttccaatacc gttttaacga gagtgatgga gccttggctg gtcaccctct
    35281 aggcaatctc attattgctg gtatctctga aatgcaaggc tcaacctaca atgccattca
    35341 aattttaacc aaatttttcc atattacagg taaaatttac ccctctagcg agcaggcctt
    35401 gacccttcat gctgttttta aagatgggca tgaagtagca ggagaaagtt ctattgccaa
    35461 ataccaaggc atgattgacc atgtctatgt gaccaacacc tacaacgacc aaaagcctca
    35521 ggccagtcgt aaggtggttg aggctattct agaaagtgac atgattgtct tgggaccagg
    35581 ctcactgttt acctctattt tacctaattt ggtcattcca gaaattaaag aagctttgcg
    35641 ccagactaaa gcagaagtgg tgtatatttg taatatcatg acccagtatg gtgaaacaga
    35701 acaattttca gatgcagatc atgtggctgt tttaaatcag cacttaggaa gagatttgat
    35761 tgatacggtt ttggtaaatg tggctaaggt gccgcaggct tacatgaatt ctaacaaatt
    35821 tgatgaatac ctcgttcagg ttgatcacga ttttgctggc ctttgcaggg ctgctaagcg
    35881 tgtgatttcg tcttattttt tacggttgga gaatggcgga gcttttcacg atggcaactt
    35941 agtggtggaa gaattaatga atttagtgag gatagtcaag caatgagttt tacaaccaag
    36001 gtcaaagagg aattaattca cttgtccaca ggtgacaaca atgaattggc cgccattatc
    36061 aaattatcag gcagcttggg cttagctcac caaagccttc atttatccat taccactgaa
    36121 aatgctaaaa ttgcccgcta catttattct tttattgaag atgcctatgt tatcgtgcca
    36181 gaaatcaggt atcatcaaaa gacgaacctg cgcaaaaacc gtgtttacac cgtctatgtt
    36241 gagcaaggtg tggaaaccat tttagccgat ttgaaattag cggactcctt ttttggtctg
    36301 gaaacaggca tcgaacctca ggttttatca gacgataatg ctggccgttc ttatcttaaa
    36361 ggggcttttt taacggcagg tagcatcaga gatcctgagt caggcaagta tcagttagaa
    36421 atctattcag tttatcttga tcacgcgcag gatttagctc aactcatgca aaaatttatg
    36481 ctagatgcca aaaccattga gcataaaagt ggtgcagtta cttatttgca aaaggcagaa
    36541 gatatcatgg actttttaat tataattggt gccatgtcct gcaaagaaga ctttgaagcc
    36601 atcaaattac ttcgagaagc tcgaaatgat attaaccgtg ccaataatgc agaaacagct
    36661 aatattgcca aaactatcag tgctagcatg aaaactatta ataatattat taaaatcatg
    36721 gacacaattg gtttagaaag tttaccgatt gaattgcaac aggtagccca gcttcgggtt
    36781 aagcatccag actattccat tcaacaagtt gctgatgccc ttgagttccc aatcaccaag
    36841 agcggggtca accatcgctt gcgtaaaatc aataaaattg cagatgactt atagaacatt
    36901 tttatcgtat gagcctttgt tcatacgatt tttctgtcta aaagtcgttt tccattgttt
    36961 ttttgaagtg tctgatgttc tgtgatatga taaaagggat aataacgttt gtaaaggaga
    37021 ctgataatgg catgtacaac tatactcgtc ggtaaaaagg catcttatga tggctcaacc
    37081 atggttgctc gaacagaaga ttctcaaaat ggagatttca cgcctaaaaa aatgattgtg
    37141 gtgaaaccag aagatcaacc gagacattac cgttcggtgc aatcttcctt tgagatggac
    37201 ttaccggaca atcccatgac ttacacgtct gttcccgatg cgcttggtaa agatggtatc
    37261 tgggcagaag caggcgtgaa cgaggctaat gtgaccatgt cagcaactga aaccatcact
    37321 accaattctc gtgttttagg ggcagatcct ctagtagctt ctggtattgg tgaggaggac
    37381 atggtgacct tagtgctccc ttatatccgt tctgcgcgtg aaggggtttt gcgccttggt
    37441 gctattttag aagactatgg cacttacgag tcaaatggtg tggctttttc agatgaacat
    37501 gacatttggt ggctggaaac gattggtggt catcattgga ttgcaagacg ggtgccagat
    37561 gatgcttatg tcaccaatcc caatcaattt ggcattgatc attttgaatt taacaatcct
    37621 gaagattacc tttgctcagc tgatttaaag gactttattg acacgtatca cttagattta
    37681 acctatagcc atgagcattt taatccgcgc tatgcttttg gtagtcaacg tgacaaagac
    37741 cgtcactata atacgccacg tgcttggatc atgcaaaaat tcttaaaccc agaaattgtg
    37801 caagacccgc gcagctttgc ccttgcttgg tgtcaaaaac cttaccgtaa aataacagta
    37861 gaagatgtca aatatgtatt gagtagtcac tatcaggaca tgggttatga cccttacggt
    37921 tcagaaggaa ctcctgttag taagaaagtc tttcgcccta ttggcattaa ccgtaccagc
    37981 caaaccgcta tcttacacat tcgtcctaat aaacctcaag aaattgccgc tattcaatgg
    38041 atggcttatg ggtcaatgcc atttaatacc atggtgcctt ttttcacaca ggtgaagact
    38101 attccagatt attttgccaa cacttacgaa aatgtgtcta ccgacaattt ctattggacc
    38161 aaccgtctga ttgcggcttt ggcagatcct cactacaatc atcatgaaac tgatttggac
    38221 aattacttgg aagaaaccat ggcaaaaggt catgccatgt tacatgctgt ggaagcacag
    38281 ttattggctg gtgaaacagt cgatttggaa gaggaaaatc aaaaaatgag tgactatgtg
    38341 caaggagaaa cgcagacgct gttgaacaag attctctttg acgctagcaa tctaatgact
    38401 aatcgtttca gtttgagcga ttaaaagtga agctaaggct gagcaactgc ttagcctttt
    38461 ttacgataac tttttaggaa aagtaatcgc aaaaagacaa aaacttggaa aaaaaatcaa
    38521 agtatgctat acttaactgg taaattttta accagttaat aacaaaggag gaatcatgaa
    38581 aaagaaaatt cttttaatga tgagtttaat cagtgtcttt tttgcttggc aacttactca
    38641 ggcaaaacaa gtcttagcag agggtaaagt gaaggtggtg acaactttct atcctgttta
    38701 tgaatttaca aaaggggtta ttggtaatga tggcgatgtt tccatgctta tgaaagcagg
    38761 aacggaacct catgattttg agccttctac aaaagatatt aaaaaaatcc aagatgcaga
    38821 tgcatttgtt tatatggatg acaatatgga aacttgggtt tctgatgtga aaaaatcatt
    38881 gacatctaaa aaagtgacca tcgtcaaggg aactggtaac atgctcttgg tagcaggagc
    38941 tggacatgac catcaccatg aggatgctga caaaaagcat gagcataata aacatagcga
    39001 agaaggacac aaccatgctt ttgacccaca cgtgtggttg tcaccatacc gtagcattac
    39061 ggtcgttgaa aatattcgcg acagtctttc aaaagcttac ccagaaaaag cagagaactt
    39121 caaagccaat gccgctactt atattgaaaa attaaaagag cttgacaaag actatacggc
    39181 agcactttca gatgctaagc aaaagagctt tgtgacacaa cacgcagctt ttggttatat
    39241 ggcacttgac tatggcttga accaaatttc tattaatggt gtcacaccag atgcagaacc
    39301 atcagcaaaa cgtattgcta ctttgtcaaa atacgttaaa aaatatggca tcaaatacat
    39361 ttattttgag gaaaatgcgt caagtaaagt cgcaaaaacc ctagctaaag aagcaggagt
    39421 taaagcggct gtgcttagtc cgcttgaagg tttgactgaa aaagagatga aagctggcca
    39481 agattacttt acggtcatgc gtaaaaacct tgaaacctta cgcttaacca ctgatgtggc
    39541 tggtaaagaa attcttccag aaaaagacac gactaagaca gtttacaatg gttatttcaa
    39601 agacaaagaa gtcaaagatc gtcaattatc tgactggtca ggtagctggc aatctgttta
    39661 cccctattta caagatggta ctttagacca agtttgggac tataaggcta aaaaatctaa
    39721 aggtaaaatg acagcagccg agtacaaaga ttactacact actggttata aaactgacgt
    39781 ggaacaaatc aaaatcaatg gtaagaaaaa gaccatgacc tttgttcgta atggtgaaaa
    39841 gaaaaccttc acttacacat acgccggcaa agaaatcttg acctatccaa aaggaaatcg
    39901 cggagttcgt ttcatgtttg aagctaaaga accaaatgct ggcgaattca aatacgttca
    39961 attcagtgac catgccattg ctcctgaaaa agcagagcat ttccacctgt actggggtgg
    40021 tgacagccaa gaaaaattac ataaagagtt agaacattgg ccaacttact acggttcaga
    40081 cttatctggt cgtgaaattg cccaagaaat caatgctcat taatcttaac tcactaagca
    40141 aatcttcttt taagtaagga ggtttgcttt ttctttgtgg agtaaaaaaa tcaataattc
    40201 tcaacattaa tttgacggac acttatgatt ataatatact ttaagtggtt ataacaagtt
    40261 agaggtgaat aagatgccaa aagaacaacc actctatcta cagattgttg atgacttgga
    40321 agtgaaaatc aaaaagagca tgacagcgaa cgataagttg ttgtcagaac gagaattaag
    40381 tgacctttac ggtgttagcc acatcacgat tagactagct cttaaagaat tagaactacg
    40441 gggcttaatt tataaaaagc agggcaaggg aacctatgtt tctggtatca aggaacccgc
    40501 cactgattta tcaagtacat atagctttac agagcagatg aaaaaaatgg gaaaaatgcc
    40561 taaaacagaa tttctttcct ttgaacagta tcaagtgaca ccctacttat ctggtctctt
    40621 ggagatagat gttgatactg acgtttttga attagagcgt ctaaggattg cagatgatat
    40681 gcccttgatg tttgaacgat cctatattcc tgctcagcct tttcaggggt taagcattgc
    40741 ggacttgaag cgtaaagctt tgtacgatat ctttgcaaag gactatcaag agacaatccg
    40801 tcttgcagaa gaagagtttt atgccagcat tgccttggac tatgaagcag gtctcttagg
    40861 cattaaaaag ggagatcctg tcttacatat tattcgtaaa acttatgatg ataaaaatat
    40921 cttaattgaa ttgactttca gtattgcaag agcagaccag tttaggtata gggtacaaca
    40981 tcaccccaac ggttaaagaa atgggaggtt aatacatgtt tacaaaatcg caggaagctt
    41041 tggaagctct tggtgcagct atcactacca aggaaattaa acaagaaccc cgtttatggc
    41101 aagaaaccat gacgtttttt gacgaaacaa gagattctct ggattctttt ttaaagagag
    41161 tttgtaaaag cgctaacgga aataacgttc atgtcatctt tacaggtgcg ggtacatctg
    41221 agtacatcgg taataccatt tgcccttact tgaagaaggt ggggaatcgg cagtgctatc
    41281 tctttgagag cgttgcttca accgatttgg ttgcggcgcc agattattat cttgctgagg
    41341 aagagacggt actattagtc tcctttgcta ggagtggtaa tagtccagaa agtgtggcag
    41401 ctgttaatct gatcaatcaa ctagtgccaa atagttatca tttaaccatt acctgcgcca
    41461 aagatggaga actggcgaaa aaagcacagc aagatgagcg ttcttacctt tatttgatgc
    41521 ctgaagacgc taatgatgct ggttttgcca tgactggtag ttttacctgt atgatgctag
    41581 cggctctttt gatttttgat gatgcgaccg acttatctca gaagcagtct tatgtggctg
    41641 atatggtttt tgctggacaa gctattcttg atcaagaaga acggctacaa gagctagctg
    41701 atttaggatt tgaatgttta gtttatctag gttctgctgg tttagccaag ttaacccaag
    41761 aagctcaatt aaaaatgtta gaattgacag ctggacaagt tgcgaccctc tacgagtcct
    41821 ctatgggctt taggcatggt ccgaaatctt ttattaatga ccgtacctta gtcattggat
    41881 ttgtcaataa tgatgcttac gtcagacagt acgatttgga catgttagag gaaatccaag
    41941 cagatggcat tgcccttaaa atcttggctc tattgcaagg aggggatatc aacttttcag
    42001 aggaccaatt ccgactagac acccgtcact tattgccaga cgcttactta gcttttccca
    42061 tgattttagt cgcgcagacc ttggccctct taacggccgt tacattagga aattcccctg
    42121 acaccccatc tgcgacagga acggttaatc gtgtggtcaa aggagtgacg attcaccctt
    42181 acccgactag tagtcgtcaa tgcaacaaag cttaaagctt ttgtgtagaa gccgtaaaac
    42241 gaaatgattt tgtgctagta ggccaaaaga aaaaccctcc tgatacagga aggttttttg
    42301 tattgtcttg cttattttgc tgcgtttgcg tctttgagac cgtatttttt gttgaagcgg
    42361 tccacacgtc catctgcttg agtgaacttt tgacgtcctg tgtagaatgg gtgtgaatct
    42421 gatgaaattt ccacacggat aagtgggtaa gtttcacctt caaactcaac agtttcttta
    42481 gaagcttttg ttgagccgct aaggaactgg taacctgtag ttgtatcaag gaaaacaact
    42541 ggacgataat ctggatgaat gtcttttctc atcttaaaaa attcctttct gccatgacac
    42601 ttgatgcatc atagttatta actattctag tgtaacaaaa cttgaatgac ttgacaaggc
    42661 ttttctttcc ttatttttta aaaatcctaa atctcttggc aaacagcgat gagttctcgg
    42721 aaaatagctt gattttcttc taaactagct gagttggctc cgctagcaag gggatgcccc
    42781 cctccaccgt gacgcttagc aatgccatta ataatctttt ctttactgcg catacgcaca
    42841 cggtagttgc cgtcagttaa ctcaacaaaa atagcccaag cttgaacgtt atcaatttta
    42901 ccaggagcac agacaatggc agagctttct gctagggtca cgtcaaaatg ttttaaggtt
    42961 tcttggctga caaggacata agcagcccca ctctcatcaa ttgttaaatg ctcaaagacg
    43021 tagctttgca gctttgctat tttcaaagga aacgaatcca tttgccttga aatcgcagca
    43081 aagtcgaact cgaaatgtct gagttggcta gcaatggaaa gggttttact agtggttgag
    43141 gcataaagaa atcgtcctgt atcaccaacg ataccagtgt ataagagctt agcagccttg
    43201 tcagagagag taagattctg actaaaggca aagtctgcaa tgatttcact tgcgctagaa
    43261 gcgcttgtgt ccacataata gaagtcacca tacacatcat cgttgggatg gtgatcaatc
    43321 ttaattaagc actgccccag tgtgtagcgc tcatcatcaa tccttggtcg attcgctgta
    43381 tctgtaatga tgaccaaagc ctctttatag tctttgtcag tcacctgatc catttggcta
    43441 atccaagcta aactaggctc atcaaaacca gtcattaaaa cctttttgtc tgggaaattt
    43501 tgtgcaataa tttctttcaa gccggcctga ctaccaagag catcagggtc aggattttga
    43561 tggcgatgga taataatagt ttggtgagct tttattttat ctaaaattgt ttcaaaagtt
    43621 gttatcatgc tttaatcttt ctttttcaaa aagaggaaaa taaccgttta acatagtctt
    43681 caaaaaacgg tttgtgtcat aaggaggtgt gcgttatgtt aagtggctaa tgctagaatt
    43741 ttttaagatt gtcaaagacc ataaattgac attttatctg aaaatcatat cctattttat
    43801 tatagcataa aagtaagctc tagataatgg taaattaatc taggaagaaa agaggttagt
    43861 tatcagttat gatactatca aagctagtct tgcaaatgca agtgaaaaaa tagtttttaa
    43921 gtgttttaag taatcatatc aaccttctcg ttaaacaatt agtgcttttc ctaaaaaagt
    43981 gtgctaaaat aaacatagtt tagtaatttt gggaggaatt tatggcatta gcaaaaatcg
    44041 tttatgccag catgacggga aatactgaag aaatcgctga tatcgttgca aataaattgc
    44101 aagaattggg ccatgatgtt gacattgatg agtgcacaac agttgacgct tcagagtttg
    44161 agaatgctga tatcgctgtc gttgcgactt atacttatgg tgacggtgac ttaccagatg
    44221 aaatcgttga tttttacgaa gatttacaag atttagattt agaaggtaaa atctatggcg
    44281 ttgtcggctc tggtgacact ttttatgact atttttgtaa atctgttgat gacttttcag
    44341 agcaatttgc gcttactggt gccatcaaag gtgcagagcc agtcaaagta gatttggcag
    44401 cagaagatga agacatcgat cgtttagagg cctttgcaga gcaactctca caggctgtta
    44461 ataatctata aaactattta gtaaaaatgt cagggacttc cttggcattt ttagattttt
    44521 aacctaaaat aaagggaatg tcacttcagg gtaggaattg aaaaaaacaa tcagcttcac
    44581 cttgcttctg aacctcttat taactataat aaaaagataa tctaatacat ctagaaaagg
    44641 aaagttatgc gtttagaaga gatacgacaa gaaatcaatg gtattgatca ccacttggtt
    44701 gccttattag aaaagcggat ggcacttgta gagcaagtaa cagcttataa actagccaat
    44761 cacttgcctg tcttagatca ggcgcgggaa aatcagatcc tagatagggt ttcttatctc
    44821 gttaaagacc aagcatttga gccagctatc catgagacgt ttaaaaccat tatgtctctt
    44881 tcacggcagt atcaaacgca acacttaaca ggtggtgaca ttaatgatta aatcaattgc
    44941 aacactgcct aaaccctcct taaaagaagc gttaggacta ataggcttgg cgcttcccat
    45001 aggggtcgcg gttggagtga ttgatgtgat ttttggtaaa gggtttttgt ttctttccga
    45061 gtatcgcgat caccaccttt tcttgcttct tccatttctt gccctagcag gccttgttat
    45121 cgtttttctt tacgataagt taggcaaaga ggttcgtcaa gggatgggat tggtttttga
    45181 ggtagggcat ggtcaaaaag atcagatttc tcctattctc attcctctta ttttgttctc
    45241 aacttgggta acccacttat ttggagcgag tgcgggtcga gaaggggtag ctgttcaaat
    45301 aggagctacc atctctcatt attgtcggag atttgtgact agtcaagaag ccgcacgaca
    45361 ccttttgatt atggggatgg cagccggttt tgcaggactt tttcaaacgc cgattgctgc
    45421 tgtcgtattt gccctcgagg ttttattggt aggaacgctt cgctactgcg ctttattacc
    45481 ttccttagtt gctgcttgcg tggcttcttg gacctctcat tctttgggat tagagaaatt
    45541 tacgattgtt cttgaagaaa cattgaccat aactccctta accttagtta aattaattgg
    45601 gttaggtctt atttttggtc tggtgggaaa tagttttgcc tatttacttg gctggtttaa
    45661 accttacctg agtcaaaagc taccaaatcc ttatctcagg attgctttca ttggtgtttt
    45721 gttatctatc tgtttgatga ttggtcacgt tggaagatat agtggtctag ggactcattt
    45781 gcttgcggca gctttttctg gccaaactat cctaacttac gactggcttt taaaaatgat
    45841 cgtgacggtg attagcttat ctgcaggctt tcaaggtggt gaagtgacgc ctctatttgc
    45901 tattggagct tctttaggca tcgttttggc cccttactta ggtcttcctg tactgttggt
    45961 tgctgcactt ggttacacca cggtatttgg aagtgcaaca aatacctttt gggcccctat
    46021 ctttattggg atagaggtct ttggtccaga gaatgcccta gcatattttg tcacctcggc
    46081 tgcagcctat atggttagtc acagacattc catttacagt tatcaaaaag tagtcatgat
    46141 caatttaaaa gacatgacgg taaatcagat ggatttaaaa aaatagcttt acaataaaga
    46201 agctttttgt tagaataaat ctcgtgtgta atggacacac gaaaattacg gctaatccgc
    46261 taagacaagt acttaagatt agtaagatag gagaataaaa atgaatccat taatccaaag
    46321 tttgacagaa ggtcaacttc gctctgatat ccctaacttc cgtcctggtg acactgttcg
    46381 cgttcacgca aaagttgtcg aaggaactcg cgaacgtatc cagatctttg aaggtgttgt
    46441 tatttcacgt aaaggtcaag ggatctcaga aatgtacact gttcgtaaaa tctcaggtgg
    46501 tatcggggta gagcgtacat tcccaatcca cacaccacgt gttgacaaaa tcgaagttat
    46561 ccgccacggt aaagtccgtc gtgcgaaact ttactacttg cgtgcattac aaggtaaagc
    46621 tgctcgtatc aaagaaattc gtcgttagtt tgaaccgaaa cgtaacgtaa tagaataaaa
    46681 agactagagt ctctagtctt tttatgtcgt cgtgacaatg tgacaattgg tgattaacgc
    46741 tatgctcgta ggacactttg aaagttcctt agcagttata agtagtatat tgtaataaca
    46801 aaatgaagca aaataaactt tcagttatct gatatttaat cttgcattac cttattttct
    46861 aggttaaaat agaagacaag gtgaatataa gatagacccc ttagttcaat ggatataaca
    46921 actccctcct aaggagtagt tgctggttcg attccggcag gggtcattat tgtcactgaa
    46981 aaagccttta catcaaaggc ttttttgtat tactcaatta atgttaggag cacaaaagag
    47041 gcagttcgat tattaaccaa ttcctcccta tttacagttg tatggctata aatggacaat
    47101 cttaagttag ggtctgagtg actaaacctg tccctaaccg cttttggtgg taattctttt
    47161 tcagctaaaa gcgaaatgtg cgagtgtttg aataagtgag tatggtaatc accataaatt
    47221 tttaggcgct tattgatgtg tgcatttaaa attggtaaac cttttgaata tggaaagctg
    47281 ttagcactct gcttgtgatt aatctatcgt atgttaaaag tgacatttaa attaaatcat
    47341 tttttataca tatatttcaa caggatttat catattggga aatagcggtg attctattgg
    47401 cattttacta ttgacaggaa tttccctgcc ttttgtctcc taaagaagat cagctttgat
    47461 ttctaacttg attagagtgg gcttggtact gtttatgaat tatcagtaca tactttctgg
    47521 agatcaaaaa ggaaaggaac agctaaagag gtgtatgtgt taccattaga ggaatagaac
    47581 atcgcaagac tcgtttattc agtcattacg atacctgttt tatttgggaa ataactataa
    47641 tattaagtga atttgtgata taatgaaagg tatgaattat caagattata tatgggattt
    47701 gggaggtacc ttactcgata attacgagct ttcaacccaa gcttttgtcc aaacgctagc
    47761 ttttttcagc cttccaggag atcacgatgc tgtttaccaa aaattaaaag aatcaaccgc
    47821 tatcgctgtg gcaacgtttg ctcctaatga gccagaattt ttgcatgtgt ataggctaag
    47881 agaagcagac aaattggcac aacccatttg gtgtttggga gctaaagaaa ttttggaaaa
    47941 gatagcgact tcaggttcgc gaaatttttt aatttctcat cgagattgtc aggtgaacca
    48001 acttttagag caagctgggt tgctaatcta ttttacagaa gtcgtgacag cttcaaatgg
    48061 ctttgctcgg aaaccaaatc ctgaaagttt gttttattta aaagaaaagt atgatattga
    48121 tagtggatta gtaattggag atcggctaat tgataaacaa gcaggacaag cagcgggttt
    48181 taataccttg cttgttgacg gtagaaaaaa cctattggag atagtaacgt agatgattga
    48241 agaaaataaa cattttgaaa aaaaaatgca agaatacgat gccagtcaaa ttcaggttct
    48301 agaagggctg gaggctgtcc gcatgcgtcc agggatgtat attggctcga cagctaaaga
    48361 gggtttgcat catttagtct gggaaattgt tgacaactca attgacgaag cattagcagg
    48421 ttttgcctct catattaaag tctttattga agcagataat tccattacag tagtagatga
    48481 tggccgtgga attccagttg acatccaagc caagacagga cgtcccgccg ttgaaacagt
    48541 ttttacagtc ttacacgcag gtggtaaatt tggcggaggc ggctataagg tttctggagg
    48601 attacatggt gtagggtcat ctgttgttaa tgctttatca acacaattag atgtgcgtgt
    48661 ttataaaaac ggccaaattc attaccaaga atttaaacgc ggggctgttg tagcagatct
    48721 tgagatcatt ggaaccactg atgtgactgg aacaacggta cactttacac ccgatccaga
    48781 aatttttact gaaacgactc agtttgatta cagtgtttta gcaaaacgta ttcaagagtt
    48841 agcctttttg aatcgtggtt taaaaatttc cattacagat aagcgctcag gtatggaaca
    48901 agaagaacat ttccattatg aaggtggaat tggttcttat gttgaatttt taaatgataa
    48961 aaaagatgtt atctttgaaa cgcctatcta tacagatggt gaattagaag gtattgcagt
    49021 tgaagtagcc atgcaataca cgactagcta tcaagaaaca gtcatgagtt ttgctaataa
    49081 tattcatact catgaaggtg gaacgcatga acaaggcttt agagcggctc ttactcgggt
    49141 catcaatgac tacgctaaga aaaataaaat tcttaaagaa aatgaggaca atttgacagg
    49201 agaagatgtt cgtgaaggtt tgacggcggt aatttctgtt aagcatccaa atcctcaatt
    49261 tgaaggtcaa accaaaacaa aattgggcaa ctcagaagtg gttaagatca ctaatcgtct
    49321 ctttagtgag gcctttcaac gttttctttt ggaaaaccca caagttgctc gtaagattgt
    49381 ggaaaaaggg attttggctt ctaaagctag aattgcagct aagcgagccc gcgaagtcac
    49441 ccgcaaaaaa tcaggcttag aaatttcaaa cttacctgga aaattagcag actgttcgtc
    49501 aaatgatgct aaccaaaacg aacttttcat cgtcgaagga gattcagcgg gtgggtcggc
    49561 caaatcaggt cgtaaccgag agtttcaagc tatcttgcct attcgtggta aaattttgaa
    49621 cgtggaaaaa gcaactatgg ataagattct tgccaacgaa gaaattagaa gtctttttac
    49681 cgctatgggt acaggttttg gtgcagattt tgacgtgtca aaagctcgct accaaaagct
    49741 ggttatcatg accgatgccg atgtggatgg cgctcatatt agaaccttgc ttttaacctt
    49801 gatttaccgc tttatgaggc ctgttctaga agctggctat gtttatatcg cccagccacc
    49861 tatttatggt gttaaggtcg gtagtgagat taaagagtat attcagccag gtattgatca
    49921 agaagaccaa ttaaaaacag ctcttgaaaa atatagtatt ggtcgttcaa aaccaactgt
    49981 tcaacgttat aaaggtcttg gggaaatgga tgaccatcaa ctttgggaaa ctactatgga
    50041 tcctgaaaat cgtttgatgg cgcgtgtgac agttgatgat gccgcagaag cagataaagt
    50101 atttgatatg ttaatgggag atcgtgttga accaagacgt gatttcattg aggaaaatgc
    50161 ggtttatagt acactggata tttagtcacc tttttagttt cacaaggaat ctgctaccaa
    50221 agaggacgaa ttgactaaaa atcatgatgc atgatgccaa cagctttgtt agttagtacg
    50281 tcttcatctt gagggacagc gttaatgcat aggtattgaa atcgcccctt aatacctatg
    50341 ttagtcctta ttaagaaagc cttgtgagtc gctggtacga gattgttgaa ttagtcaaat
    50401 atattttgaa atgcatttta aagtatgtta taatcgtaat gttatagtgt attttaaata
    50461 aaattttaat aaaaggcgat tgaggaattt cagtttttag ttattactgg aacaatgttg
    50521 ataaatcgtg tctaaataat aaggagattc agatgtcaag cggaattatc ttgctgattg
    50581 tggctatagt cctactagtg attatcgcct atctagtggg tgtcatcata cgaaagcgta
    50641 atgattccct aattaccagt ctagaagaac gaaaacaggc cttgtttgct ttgcctgtta
    50701 atgatgaaat tgaagaagta aagtcacttc atttgatagg acagagccaa acctcttttc
    50761 gggaatggaa tcagaaatgg gtagacttaa ctgtaaattc gtttgcagat attgaaaatc
    50821 atatttttga agctgaaaat ttgaatgata cgtttaattt tattcgcgcc aagcatgaga
    50881 ttaatagcgt tgaaagtcag cttaatcttg ttgaagaaga tatcgcttct attcgtgaag
    50941 cacttaatat cttaaaagag caagaagaaa aaaatagtgc tcgtgtcacc catgctcttg
    51001 atttatatga aaagctccaa gcttctattt ctgagaatga agataatttt ggttcaacta
    51061 tgcctgaaat tgacaaacag atgaaaaaca ttgaaactga attttcacag tttgtcgcac
    51121 tcaactcatc aggtgatcct gtagaagctt ctgaagttct ggatagagca gaagagcata
    51181 ctattgctct agggcagatt acagagcaga ttccagctat tgtggccaag ttggaagatg
    51241 attttccaga tcagttagat gatttggaaa caggatatcg ccgtttactt gaagaaaact
    51301 atcattttcc agaaaaaaac attgaggcac gttttcagga gattcgtgag tctattcgtg
    51361 ccaattcatc agagttagtt acacttgact tggatcgtgc tagagaagaa aacacgcata
    51421 ttcaagaacg cattgattct ctttatgaag tctttgagcg cgaaattgcc gcttataagg
    51481 tagctgctaa aaatagtaag atgctacccc gttacctagc acatgtgaaa cgtaataatg
    51541 aacaactcaa aaatgaaatt gcacgtttat cacgtaaata tattctaagt gaaacggaaa
    51601 gtctgactgt taaggcattt gagaaggata ttaaagagat cgaagacagt acacttgctg
    51661 ttgcagaaca atttggttta caagaaaaac cattttcaga actgcaagtg acttttgaac
    51721 gcagtataaa gacgcttact aatgttgagt caggtcaaat ggatgttttt gcagcagtta
    51781 aagatattga aaaaattgaa tcacaggcac gccataacct tgatgtttat gttactcagc
    51841 ttcatatgat taaacgttat atggaaaaac gtcacttgcc tggaattcca caagactttc
    51901 ttagtgcttt ctttacaacg agttcacaat tggaagcttt gatggatgag cttagtagag
    51961 gacggatcaa tattgaggca gtgtcacgtt tgtcggaagt tgcgacggtt gctattgcta
    52021 atctagaaga tttaacctat caagtggttc aaaatgctac cttgactgaa caattactac
    52081 aatattctaa tcgctatcgt tcttttgaag caggagttca aagtagtttt gaacatgctt
    52141 tgagactttt cgaagtagaa aatgattatc aggcttcttt tgatgaaatt tcttatgctc
    52201 ttgaaacagt tgaacctggg gtaacagatc ggtttgttaa ctcttatgaa aaaacacgag
    52261 agcacattcg tttttgatac ttgaaagtcg tgatattctc acgacttttt attagctttt
    52321 tggaccaata cgtgtttttg actagaatct tctttttaat gatcaaacga agaagtagta
    52381 acagtgtttt ttggtattga gaggatagtt attttttcaa aaatcttttc caaaaggatt
    52441 tggttttttc aggaggttgt ttgctaagtt gatcgttttt tgtctgcttt aagatgactt
    52501 ctaaacgcgt ttcctttaga tttattgcgt ggtcggtatg aaggataaac gcaaaaggtg
    52561 aagtcatatg cgtttctgta ataatagtaa caggtaaatg gttttctttt gctaatttca
    52621 tatagagtat ttgaagttga ggtgccagct tggaagagat ttttaagtgt aaaggttgat
    52681 agactaactg aaggctcggt aattctcttt tcaaatagtc ttttactgtt ttagtttgag
    52741 cttcgtctaa taaagcactt aaaacgactc gttcagcata cgttcctaga tagtagcgtt
    52801 gctgctcagg atttaatctt ctttctcccc aggctccttt taatagctta tcttctaaat
    52861 tagtcataga taccctcgct tctttataat agtttcttta ttatatcgat ttctacaata
    52921 aaataccaat ttgaaaattt tcggtaaatg tgttaaaaaa caagaaagaa agtgattttt
    52981 cttgcaaaaa acaaaggaag cttttcatga gattgctttt taagttgatt aaaggcctag
    53041 tttgtggtat tatgaacatg taaaatatta aaactcataa ggagagtatt acaatgtcaa
    53101 ttattactga tgtatacgct cgtgaagtcc ttgactcacg cggtaaccca acacttgaag
    53161 tagaagttta tacagaatca ggtgcattcg gacgtggtat ggttccttca ggagcttcaa
    53221 ctggtgaaca tgaagccgtt gaacttcgtg atggtgacaa atctcgttac cttggtctag
    53281 gtactcaaaa agcagttgat aacgttaata acattatcgc taaggcaatc atcggttacg
    53341 atgttcgcga tcaacaagct atcgaccgtg caatgatcgc tcttgacggt actcctaaca
    53401 aaggtaaact tggtgctaat gctattcttg gtgtttctat cgctgttgct cgtgcagctg
    53461 ctgactatct tgaagtgcca ctttacactt accttggcgg attcaacact aaagttcttc
    53521 caactcctat gatgaacatc atcaacggtg gatcacactc agatgcccca attgcattcc
    53581 aagagttcat gatcatgcca gttggtgcac ctactttcaa agaaggtctt cgttggggtg
    53641 ctgaagtttt ccacgctctt aagaaaattc ttaaagaacg cggacttgtt acagctgtag
    53701 gtgacgaagg tggatttgct cctaaatttg aaggaactga agacggtgta gaaactatcc
    53761 ttaaagctat tgaagcagct ggttacgaag ctggtgaaaa cggcattatg atcggttttg
    53821 actgtgcatc atcagaattc tacgacaaag aacgtaaagt ttacgactac actaaatttg
    53881 aaggtgaagg cgctgctgtt cgtacatctg cagaacaagt tgattacctt gaagagttgg
    53941 ttaacaaata cccaattatt actatcgaag atggtatgga tgaaaacgac tgggatggtt
    54001 ggaaagttct tactgaacgc ctaggcaaac gtgttcaatt ggttggtgac gacttcttcg
    54061 ttacaaacac tgaatacctt gctcgtggta tcaaagaaaa tgcagctaac tcaatcctta
    54121 tcaaagttaa ccaaatcggt actttgactg aaacgtttga agctatcgaa atggctaaag
    54181 aagctggata tactgccgtt gtatcacacc gttcaggtga aactgaagat tcaacaatcg
    54241 ctgacatcgc agttgcaaca aacgctggcc aaatcaaaac aggttcattg tcacgtacag
    54301 accgtattgc taaatacaac caattacttc gtatcgaaga tcaacttggt gaagttgctc
    54361 aatacaaagg tatcaaatca ttctataact taaaaaaata aattagtcta gtggactcat
    54421 ttatcctgag ctaatgtatt agcgaggtaa agttattgag gaaggcttgg atatgttatc
    54481 caagtctttt ctttttgcag taagacagaa atcggtcatt cgtagaatgt gatttcgtcg
    54541 tcgcacctcc gtcaggctga ctagcttggt cacgacaaaa ggagtgaaca tccagtcagc
    54601 tacgacgcaa aagttaaaga atagaaagct tgggaaaatc ccaagctttt tgatttctaa
    54661 atagtgaaaa tttactgtgg actcatttat cctgagttaa tgattcgtga gaaaaactta
    54721 acaacttgtt aaaaaacttt ggttctgata atacaggacc aaagtttttt tatttagtaa
    54781 aaacgtcgtg gtataggttt gtccaggtat tacatatttc aaagtagtat ctaggatgaa
    54841 gtaaagatat tagctagggt tatcaaaatg atataagtta taaagcttta aaaattagct
    54901 ctcatttttg tcgttattgt ttgaaaaata tagtttttta gagaaaatta ttattttttt
    54961 tgtcattttt gataatatta aaaagaaagg gtttacatat taatcatttt ttactataat
    55021 aaaagtgata agaactagat agttgttgtg ttacaacagt acaattgagc tagccttgtc
    55081 cttgttgtgt taactttatt tttaaaataa ggttaaaaat aaacgactcg tgttcttatc
    55141 agttacttat tagataagga ggtaaacctt atgttaaaat ttacttcaaa tattttagct
    55201 actagtgtag ctgaaacaac tcaagttgct cctggaggct gttgttgctg ctgtactact
    55261 tgttgcttct caattgctac tggaagtggt aattctcaag gtggtagcgg aagttatacg
    55321 ccaggtaaat aatctattta gcatctctat gtgatagtga tattaaggta atgagtttgc
    55381 tagcaactaa gttatctttg gtaacttctg attatagatg aatggcatag aggtgttaga
    55441 aaacatgaga caaaagtaat cttcttgatg ctaacgtctc aggtaattag caggtactag
    55501 acagtacctg ctaattacta tatgtttagt aaaatgagat aggaaagata gttatgtcat
    55561 tttttacaaa ggaacaacag cctaaagaga attgtccgcc aataactgtt gaaaaagcaa
    55621 ggcaattgtt tgaatttaat acaaaccact tgtccttatc ggattaccat catcaaacgg
    55681 tgctaaaaac gtcaaagcag ctagttgctc aacatttgat gcctaatgca accgataatc
    55741 ttagtcaaca ttttttgatg aactataaag ctaataataa ttatttaggc ttccaagcta
    55801 gtattgtcga cttttttaca gattctgccg ttgctaattt ttcaagtagt tacgtttatg
    55861 aaagtcagga aaagataatt cgtttaccaa aacctaccaa gatatcaact gctctgtcga
    55921 catgtattat aaaacgaaga agtcatcgtc aattttcaga tagacaaatg cctcttcaag
    55981 atttatcaaa cattctttat tatgcatgtg gtgttagttc acaagcatca attagagatg
    56041 gagcatcaga taagattaca ctcagaaact gtgcttcagg tggaggttta taccctattc
    56101 atttagtttt ttatgctaga aacatcagta aattaataga tggtttctat gaatacctac
    56161 cctatcagca tgcactaagg tgttatcggc atagctctga ggaaaacgtt agagattttg
    56221 cggaatacgg tgctattaat gctgaaaatt gtaatattat tattatttat gtctaccatt
    56281 acataaaaaa tacacgtaaa tatgggaatc aggcgactgc ctatgctttt attgaatcag
    56341 gagaaatagc ccagaatatt caattgactg caactgcctt aacttatgga agtattgata
    56401 ttggtggtta taataaggaa tatctccaag aattattaga tttagatggg ctaggagagc
    56461 atgtgattca catgacactc gtaggaacta aggagtctca atgaaatatc aacttaatag
    56521 taatgttcgt gtcgtgacat ttcaagatac attttgtttt agaaaaggaa tctgggactt
    56581 taatgaagcc attctagatt tgacacaaga acctcaaaat ttaaagatag tttatcaaga
    56641 aatagtttca cagttggtta agggagtagc cattgatact gaaacttatg aaaatacttt
    56701 agaacctgag acgttcgcta atttaatgga agtcatttca ggcttgtatt acaatgatat
    56761 gctgatgctt gaggatgact acaatcttga agaaaatatc atgaaaattt taatgggtaa
    56821 tttccgtttt atggcgcaag caggtcatat ggtaagcaat gatcctgttt tgtttatcag
    56881 tgattcgact tatgttaatg aatctgctga gttgctagct gaacaactgc atttacaatt
    56941 gcaagtggct agcgatgact taaaaatgtt aattcagcag acagatgtta gttcgcgttt
    57001 agatgctttg gagcatcgcc gtaacatgaa ttgtttatca gatgccttgt gcgattacca
    57061 aagtattatt atttgtcaag agcgcttgaa tattatgatg ttgcgacact tgaatgaagt
    57121 tagcgtagct atgaaaaaac aattagtgat tggttttgta gatggaccat tcttgcacac
    57181 ttgtactttg aatcctcctc atagtgctga ctttgatagc ttagaaagaa gagttttggc
    57241 acgtttacaa gactcaactc tctatcaaca ttttgctaat cagattttac cagcaacaca
    57301 agatgtgagc caggcctatt taccattgtt aaatgtttta atgaatttag ttgttagcga
    57361 agctttcatt attgctcaaa caggtagttc taaatttgag ggacgtttat taagcattta
    57421 cttaccgacg cttgagattc aggtccaaga tattttgaaa atgtctaatt cacagacaca
    57481 aggagctttg gcaaaattaa agtatgagga tcagcagata tcaacacgtg agattgttaa
    57541 aaaactcctt gacgagtaac ctataaggag aatctattat gttatactat tatccttctt
    57601 ttaatcatat ttttgatgaa ttaaaaagtt taagtggcaa tcgaacaggt atcttaaatc
    57661 aatctcaagt tccagtttgc aaccatcctc acgatgttta cttaaaaagt attactggcc
    57721 aaatgccaga ttatcataaa caatttatag gtgagttgag tcaagttagt tatcacatta
    57781 ttggttacgg cagttactat gaagaagcac ttatcaagta tttaggagaa agtattgaac
    57841 gctatgctac tgtaattgcc ggagacttac tatcagatcg gattgtctat gcttcttata
    57901 atgagttaaa actgttacat aaagtgatgc ctttagaata cttgcaagtg tttacccaag
    57961 aacagatcgc attatcttgt gacttgcaaa tgatgatgtg cgataaaatg gtaactgaga
    58021 acgatgtatt gggctgggtt aaatgtccca tgttctttga ggacgcagag atgtatgttc
    58081 cagctcaaat gctttgtgtt gggtataaaa caaatgagac tgtaggagaa agacggataa
    58141 taccaggatt ttctacggga acagcttctc acaaaacgtt agaagcggct atgtgcaaca
    58201 gtttgattga atacatccag atcgattcaa tgatgcttag ctggtatact aagaagcctt
    58261 gccccaagat tattgttgat gatcctgata ttgaagtgat tttagaagaa gctagactgg
    58321 gaaaagacag tctatacgac attattccta tcgatatgac tgtaggagaa gataatcctc
    58381 tttatacgtt tggaatcatt ctcaaaaata aatatgatga agggccttac ctcttgtttg
    58441 gagtgcaggc tgggttagat cctaaacatg ctttgctaag agggatcatg gaagcttcag
    58501 ctattagcta tagttactac tataatcttt tatatcaaaa agcttccctt gcaaatattg
    58561 aatgcgaaga acctttgttt ttagatttag atagtaatgt cttctattat gcacatccca
    58621 aggaccaaga ccataaatgg aaggcctttg aacctttgat ttcaggagaa gttctgttaa
    58681 gtgatttgga agatcattct ggtaaagata aaaaagaaga tttgaagact ttattagctt
    58741 atgctaagaa agtcagtcct aatgctgtct ttttagatat tacacctcct gaagctctag
    58801 aaaaaggctg gtacgtcacg cgagttctga tgccagaact tcttgaaatg tgtataccag
    58861 catttccttt tgctaatcat ccacgaatga gacagtttgg aggtgtaaca aatgcctttg
    58921 tccatccaat gccttaatct ttgttttttg ttggtaactt tttgtccttc aattcctatg
    58981 caagctattt ttggaaaaga agatagtggt tatgcattta atttaattgg ttttctaaga
    59041 gcaactctga tttatgacat tttggctttg gtaagtattt atgttttgtc acctcaaata
    59101 accttgtctc ttgaaagtat tgatagtaag acgttcttta tgggacttgt attttgcgtc
    59161 ttgatagtac tgattgaact cattttctta catggtttac gttgttggca aaaaaagcaa
    59221 tggcttcctg caactttctc gtttgtagga acgacaaatg attggtctaa gattggctat
    59281 cctttattac tagctttatt tgaagagacg atttatcgtt ttttgtggtt taatatatta
    59341 gcttttcaat ggcatttacc aacaattatt gttttaattg taactagttt ttgctatgct
    59401 ttaaatcact tattgatggg gaaatccatt ttttatgcta agttggtaac aggcatcatt
    59461 tatggtagta tttacatgct gactagtcaa ttgtggttgg ttgtgataat gcatgtagga
    59521 ggtaacttgc tagttgagtg tcttagccat cttcaaacaa aaaagaagaa ggaggtgaca
    59581 tgatgctatt ggttttgctg tcgtttttag gtctaactac tctttggttg accagttatc
    59641 gaagacgttg tttggctaga tggcatcttc aatggttaat ggccttatcc tatcaagatt
    59701 ttttagatgt cttactgagt ctgtttcaat ttgtcgttat tatacttgtt ttgttctttt
    59761 actcagctac tattaatcta ggagaggttc tgaccttttt gacacaaact agctggcatt
    59821 ggcagattct ttgttattta gtgttatatc ttatggccat catagagatg acgcttttag
    59881 ttttaattct tatctttgac gttttgctcc agaaagatag tcgattgctc tttaaaaaaa
    59941 taacttggct gccttttaga caagataaac cagtcttaag tatacttttg ctaggcatag
    60001 ttattctagt agacagtctc ttttatttgg gcttgcttat attattagga gaacagtcgc
    60061 taacaagttt agcaacgctt attttaggtt atgggatagt caaggcttgt cgctattcag
    60121 gttggttaaa tgtactatta gctttttgtc ttttcactat agttggacta tgggcagtta
    60181 cggcaacctt attatatggt tggctagtag gtgcgatgat attaacggtg acttatttga
    60241 tgattagttg caaagagtat tagcaatatt aaaaaggagt gatatatgag ttttgtacaa
    60301 ttaacaaatg ttgtcaagtc ctacaaaaac ggcaagaaag ctgtcaatga tgtttccttg
    60361 tctattgaag caggtaatat ttatggtctg ttaggaccaa atggtgctgg taagtctacc
    60421 ttgattaatc ttatcttagg cttgatccct ttgagttccg gtaaaattac tgttttaggg
    60481 caatcccaaa agactattcg aaaaataagt tcgcagatag gttatgttcc tcaagacatt
    60541 gctgtttatc cagacctaac tgcttatgaa aatgtagaac tatttgggtc actttatggc
    60601 ttaaagggag ctcagcttaa aaaacaagtt ctaaaaagtt tagaatttgt ggggctacac
    60661 tcccaagcta agcagtttcc aagtcaattc tcaggaggaa tgaagagacg gttaaatatc
    60721 gcttgtgcgc tagttcattc acctaaatta atcatttttg acgaaccgac tgtagggatt
    60781 gatcctcaat cacgtaatca tattttagag tcgattcgtt tgctaaacaa agaaggtgcc
    60841 acagttattt atacgaccca ttatatggaa gaagtagagg ctctttgtga ttatattttt
    60901 attatggatc atggtcaagt tattgaagaa ggacctaaat ttgaactgga aaaacgttac
    60961 gttgcaaatc tagcaaacca gattattgta actctaacag attcacgtca tttggaactg
    61021 gcagataagc ctgattggtc tttgatagaa gatggagaaa aactcatgtt gaagattgat
    61081 aatagtgata tgacatcagt tgttcatcag ctcacacagg ccaatattac ttttagcgag
    61141 attagacata accatttgaa tttagaagaa attttcttac acttaacagg taagaagtta
    61201 cgagattaga ggttactatg gttttatttc atttaatcaa aaaagaaagt ttacagattt
    61261 ttagaaaccg aacagcctta ttgatgatgg tgatttttcc aattttgatg atcgttattt
    61321 taagttttgc ctttaaatca agttttaata ctgcgacaac agtccctaaa ttgaccattc
    61381 gttaccaatt agagggtgaa aaaacggatt accagaaaaa ttttcttgct tttttaaaag
    61441 ttttaaacca aaaacttcat ttagaggcta aacctagtaa ttctcttgaa aaagatcgac
    61501 aaagggtcag tgaaggagcc ttaacggctg ttttagaagt gaagaagaat cagaccatta
    61561 aggttattac taataatatt aatcagcaaa atgcagattt aatcaatatg ctagtaaaaa
    61621 attatgtaga taatgctaaa acttatgact cgatagcagc tctttatcct caacaattaa
    61681 atcatatcag aaagcgaagt gtggactatg ttaaggtcag ttcaatacag acaagtaaag
    61741 gaatgacatc agctgattat tatgctattt ccatgtttac catgattact ttttatagta
    61801 tgatgtctgc gatgaacctt gttttgtcag atcgtcaaca acggattaca aatcgtattc
    61861 gcttaacagg agtttctcca agtcttttgg tctttgggaa attaataggt gctatgttag
    61921 caacaactgt tcaattgagt cttttataca tttttacaag gtttgtttta cgagttaatt
    61981 ggggcactaa tgagtggatg cttattggta taacagcctc cttagtctat ctctctgtag
    62041 ctataggtat cgggctaggt ataagcatta aaaatgaggc ttttttaacg gttgcatcca
    62101 atactattat tcctatattc gcctttttag gaggcagtta cgttccattg acaacattac
    62161 acagctctat tattaatcaa ttgtcgaata tatctcctat taaatgggtt aatgatagtt
    62221 tgttctatct tatttttggt ggtcaatata atccgattcc tgtaactttg atcgttaata
    62281 ttagtatcgg aacaattttt ataatattgg cattgatagg tatgagaaag caggtgacga
    62341 catgatttgt tttataaaaa ctctatttgt taagataaag cgcaaaaaaa caagttatgt
    62401 gacattcttt ttaatgccta ttttaacgac acttttggct ttatctttga gtttttcaaa
    62461 taataatcag gctaaaattg ggatattaga taaagataat agtcagatat ctaaacaatt
    62521 tattgctcaa ctaaagcaaa acaaaaagta cgacattttt accaaaatca aaaaagagca
    62581 tattgatcac taccttcaag ataaatctct agaagcggtg ttgactattg acaaaggatt
    62641 ctcagataaa gtgttgcaag gaaaatctca aaaactcaat atacgttcga ttgctaatag
    62701 cgaaattaca gagtgggtaa aggcacagac caattatcta ttggaaaact ataatattat
    62761 aggggatgtg gctctaggta acgaagatac ttttaataga attctccaaa aaaaccaaca
    62821 gttaaattat ggtgttaagc aagtaacttt gacagaccga tcacgtagca aagcagtatc
    62881 ttccacaacg acaggatttt tgcttattct aatgttaggt agtacgagcg tgatttacag
    62941 tggtattttg gcagataaat ctagtcagtt ataccatcga ttaatgttat cgaacttatc
    63001 tcgttttcgc tatatgttga gttacgtctg tgtaggattt gttgctttta cgattcaaat
    63061 tgtcattatg ctgagtttgt taaaagtatt taatattagt ttttttgttc cgacatcact
    63121 tcttttgatt atttttttcc tttttagttt attagcgata ggctttggcc tgctgattgg
    63181 agctatcaca caaaattccc aacaaagtag ccagttagct aatcttattg taatgccgac
    63241 ttcaatgttg gctggctgtt tatggccatt gtctattacg ccttcttata tgcaagcaat
    63301 tggtaagtta ttaccacaaa attgggtttt atcagccata gctatttttc aaagtggagg
    63361 gaccttatct caggcttggc catacttgtt agctctaatg ggaacagcac tagctttgat
    63421 tattttttca agtttattat taaaacctac cagactataa ttagtctttt gttaaaaaat
    63481 actttcctaa ttagctaact accaggtagc tcttttattg gcttatatgc aataaaaggg
    63541 ttgctttttg cttatatttt ctctagtgca cttatctttt gttaaaagcg attgcgatgt
    63601 tactgttgtt actgtgtttt ttagagagca tattatcaaa agcgacctct ctagaaagtt
    63661 cgtttttgtt gataaatgag ttgtcaaagt attttaaaaa aacgttttca ataaacataa
    63721 aaactaatgt tattaaaaaa aggtgtaaaa acgtatttat tttatgaaat gtttttgtta
    63781 caataagcat gtatcgaatg ctataaagct gtcttgttcg ctatcagggg cgcttgtgat
    63841 gttatgtcag atcaaacaag tctttaattg ggtgacttaa cagattaaaa gaaaagatct
    63901 aatcgtgtta cttgatagta taattaatgc aaacagaaag tgtatcccaa ttcatagtct
    63961 caggtggagg ttaatattca aaaataaaat cttgttgttg tcttaaacta atcacattaa
    64021 aaggagatat catgattaac aagaaatgta taatacctgt ttcattgttg acactagcta
    64081 ttacgcttac tagtgttgaa gaagttactt cacgtcaaaa tttgacttat gccaatgaaa
    64141 tcgtaacaca aaggccaaag agagaatctg ttattagtga taaaacgaat tttcccgtca
    64201 tatcacctta cctagcaagt gtggattttg gtgagagaaa aacacctttg ccaacacctg
    64261 ataaaggagt aaaagtaact actgaacagt ctattgctca agtaagaaag gggcctgaag
    64321 aaagaaccta tactgttact ggcaagatta cgagtgtgat caatggctgg ggaggctatg
    64381 gcttttatat tcaagatagt gaaggtattg gactttatgt ttatcctcaa aaagatttag
    64441 gatacagtaa gggagatatt gttcaattaa caggtacact tactcgcttt aaaggtgatt
    64501 tacaactcca acaggtgact gcacacaaaa agttagagtt atcttttccg acttctgtta
    64561 aagaagcagt aatatcagaa ttagaaacaa caacaccctc aacattagtt aagttatctc
    64621 acgtgacagt tggagaatta tcaactgatc aatataacaa cacatctttc cttgtaaggg
    64681 atgatagtgg taaaagtata gttgttcata tagatcatcg tacaggggtt aaaggggctg
    64741 atgttgttac taaaataagt cagggtgatt tgattaacct cacagccata ttgtctattg
    64801 ttgatggtca gttacaatta agaccgtttt ctcttgaaca attggaagtg gttaaaaagg
    64861 tcacaagctc aaatagtgat gcttcatctc gtaatattgt gaaaataggc gagattcaag
    64921 gagccagtca tacgtcgcca cttctcaaaa aagcggtcac cgtagaacag gttgttgtca
    64981 cttatttaga cgattccact catttttatg ttcaagatct taatggtgat ggtgatttag
    65041 cgacttcaga tggtattcgt gtttttgcta aaaacgctaa ggttcaagtc ggcgatgttt
    65101 tgaccatttc gggtgaagtg gaagaattct ttggtcgtgg ttatgaggaa cgtaagcaga
    65161 ctgaccttac catcacccaa attgtggcta aagcagtgac caaaacaggg acagctcaag
    65221 ttccatcgcc gcttgtttta gggaaagatc gtatcgcgcc agccaatatt attgataatg
    65281 atggcttgcg tgtgtttgat ccagaagaag acgctattga ttattgggaa tcaatggaag
    65341 gcatgttagt ggcggttgat gatgctaaaa tccttggtcc aatgaaaaat aaagaaattt
    65401 atgtcttacc tggctctagt acaagaccgt taaataattc aggtggagta ttacttccag
    65461 ctaattctta taacacagat gtgattcctg ttcttttcaa aaaaggcaaa caaattatta
    65521 aagcaggaga ctcttacaaa ggaagattag ctgggccagt atcttatagc tatggtaatt
    65581 acaaggtctt tgttgatgac agcaaaaaca tgccaagttt aatggatggt catctaaaac
    65641 ctgaaaaaac aaacttgcaa aaagacctta gcaagttaag cattgcttct tacaatattg
    65701 aaaacttctc agccaatcct tcttcaacta aagatgagaa ggtcaaacgg attgccgaat
    65761 cctttattca tgatctgaat gctccagaca ttattggatt aattgaagtc caagataata
    65821 atgggccgac tgatgatggg acaacggatg cgacacaaag cgcgcaacgc ctcattgatg
    65881 ctattaaaaa actaggtggc ccaacttatc gttatgttga tattgctcca gaaaataatg
    65941 ttgacggagg tcaaccaggt ggtaatattc gaacaggatt cctttatcaa ccagagcgcg
    66001 tcagcctttc tgataagcca aaaggcggtg ctcgtgatgc tctaacttgg gttaatggag
    66061 aattaaacct tagtgttggt cgaattgatc caactaacgc cgcttggaaa gatgttcgta
    66121 aatcactagc agcagaattt atcttccaag gtcgtaaagt cgttgttgtt gcaaatcatt
    66181 tgaactctaa gcgtggggat aatgctcttt atggtcgtgt gcaaccagtc acttttaaat
    66241 ctgagcaaag acgtcacgtc ttggctaata tgctagcaca atttgcgaaa gaaggggcaa
    66301 aacaccaagc taatattgtg atgctaggtg actttaatga ttttgaattc acaaagacga
    66361 ttcaattaat cgaagaaggt gatatggtta acttggtgag ccgacatgat atttcagatc
    66421 ggtattctta ttttcaccaa ggcaataatc agacccttga taatatatta gtttcacgcc
    66481 atttacttga tcactacgaa tttgacatgg ttcatgtgaa ttccccattt atggaagctc
    66541 acggacgcgc atcagatcat gatccattgt tacttcaatt atcattttct aaagaaaatg
    66601 ataaggcaga gtcttctaaa caaagtgtaa aagctaaaaa aacttcaaaa ggaaaactgt
    66661 tgccaaaaac aggagatagt cttgtttatg tgataacgct actaggaacg gctagtttat
    66721 tagtgcctat tttattattg actaaaggca aaaaggaatc atagcgattt gaagaattgg
    66781 agttcataaa gagtcgttaa aggcttgata tacttacgtt agaccttaag ctaaaatgga
    66841 tgactatata aaaactaata ttgataacaa aagaagataa caataagaca gctttacttg
    66901 ctaaagactt ttgtcaagct aattgtttta tggtacaatg taaccgttgc tttgcaaccc
    66961 ttggtgctta gttccctttc accaagcata ttagaaacgt agatagcttt tgagagttat
    67021 ccagacgtta aaggagaaaa aatgacaaaa ttgactgtac acgactatgt tcacattggg
    67081 ctagtagctg ccttgtatgt tgtcttaact attaccccac ctttaaatgc gatttcttat
    67141 gggatgtatc aatttagaat atctgaaatg atgaatttct tagcttttta tcatcgcaag
    67201 tatattattg cggtaactct tggatgtatg attgctaact tttatagttt cggactgatt
    67261 gatgtctttg taggcggcgg ttcaactctt atttttgtga ccttaggtgt gattttgttt
    67321 agtaagtatc aaaaagatta tctttttaat ggcattttta ataaagcttt tgtttacttt
    67381 tctttctttt ttgcaacttc catgtttact gtagcaatcg aactttactt ctttggagct
    67441 ccatttttat taacatggtt tacaactgcg ttaggagaat tagtatctct gctcatagga
    67501 tcacttatta ttgataagtt gtctcaaaga atttcctttt agtaatgcat catactcaaa
    67561 agagttgggt caataccctt ctctttttta tgttgtttgt aatgttaaaa tcgttctaga
    67621 tagaaatatt taacacttta gctaatagta ccatatggag tggccaacga ttacttttga
    67681 tgttgttatg atatagaaat agctcatttg ttatctttta tgataaaata aaagtatgaa
    67741 aaaacgcata aaagaattaa cagatcttct taaccgttac cgttatgact attatactaa
    67801 agatgcccca tcagtttctg acagtgacta tgataagctt tatcgtgaac tggtgacttt
    67861 agagcagtca tatcccgagt atgtcttgca agatagccca acgcagcagg ttggagggac
    67921 tattttaaag gggtttgaaa aatatcgaca tcagtatccg ctttttagtt tgcaggatgc
    67981 tttttcacgt gaggagctgg atgcttttga taagcgcgtc aaggccgaat ttccgaatgc
    68041 cacctatcta gcagagttaa aaattgatgg tttatctatt tccttgagtt atgagaatgg
    68101 cttcttacag gttggagcaa cacggggtga tggcaatatc ggtgaaaata tcacagaaaa
    68161 tatcaaaaaa ataaaggata ttcctcacca attgagtgag cctttaacca tcaccgttcg
    68221 aggagaggct tacatgtctc gtcagtcctt taaagcgatc aatgaagcac gccaagaaaa
    68281 tggggagact gaatttgcta atcctagaaa tgctgccgct gggacactaa ggcagctaga
    68341 tacgtcagtg gttgctaagc gtcaactagc cacttttttg tatcaagaag ctagtccgac
    68401 agctagaaat caacaaaatg aggtcttagc agaattagca gatctaggtt tttcagtaaa
    68461 tccgtattat caactcacat cgtctatgga tgagatttgg gattttatca aaactattga
    68521 ggcaaaaaga gatcaattag cttatgacat agatggcgtt gttattaaag ttaatagcct
    68581 agccatgcaa gaagagctag ggtttacagt taaagctcca cgctgggcca ttgcttacaa
    68641 atttccagca gaagaaaaag aggcagaaat cctttcggtt gactggacag tgggacgaac
    68701 aggcgtggtc acacctacag cgaatctaac tcctgtgcaa ctagcgggga caaccgtgag
    68761 tcgtgcaact ctacataatg tggattatat tgccgaaaaa gatatccgta ttggcgatac
    68821 agtgattgta tataaggcag gggacattat tcctgctgtc ttaaatgtcg ttatgagtaa
    68881 gcggaaccag caagaagtca tgcttattcc taaactatgc ccatcttgtg gtagtgaatt
    68941 agttcatttc gaagatgagg ttgctttgcg ttgtattaat ccgttgtgtc ctagtttgat
    69001 tcagcgaagt ttggagcatt ttgcaagtcg tgatgccatg aacattactg ggctgggacc
    69061 agctattgtg gaaaaactat ttttagcggg gtttgttcat gatgttgctg atatttacca
    69121 gttgaccaaa gaagatttca tgcaattaga tggcatcaaa gaaaagtcag ctgataaatt
    69181 gctcgctgcg attgaggctt ctaaatcaaa ttcagctgaa aaactgttat ttggtctagg
    69241 aattcgtcat attggctcta aagttagtcg cttaatttta gaggtatacg gagatatttc
    69301 tgctctttta accgctaaag aagaggaaat cgcaaggata gatggccttg gctcaacgat
    69361 tgctcaatca cttactcaat actttgaaca aaaaacggct gcgattttag tagacgagtt
    69421 aaagacagca ggtgtcaaca tgcattactc aggtcaaaaa gttaatagtg acgcagcgct
    69481 ttttggtcta actgttgttt taactggcaa attaaatcag ctgaaccgaa atgaggccaa
    69541 agataaatta gaggcattag gtgctaaagt tactggaagt gtatctaaga aaacagattt
    69601 agttattgca ggtagtgacg ctggttctaa gctagaaaaa gcaaagagct taggaattcg
    69661 gattgaagat gaagattggc tacgaaagtt ttaagtgagg taatgttatg aaaaaacaat
    69721 tgagagcacg tctcatttat aatccaacgt caggacaaga acttatgaga aaaagtgttc
    69781 ctgaagtttt agacatatta gaagggttcg ggtatgaaac atctgccttt caaacaacag
    69841 cccaaaagaa ctctgctcta aatgaagcaa gaagagcggc aaaggcaggt tttgacttat
    69901 tgattgctgc tggaggtgat ggcactatta acgaagtggt caatggaatt gctcccttga
    69961 aaaagcgccc taaaatggcc attattccaa caggtaccac taatgatttt gctagagcgt
    70021 taaaagtacc aagaggaaat ccgagccaag cagcaaaact tatcggaaaa aatcagacta
    70081 tccagatgga tattggtaga gctaagaaag atacttattt catcaatatt gctgcagcag
    70141 gaagtttgac ggaattaact tacagtgtac caagtcagtt aaaaacgatg tttggatact
    70201 tggcttatct tgctaaagga gtagaactgc tcccaagagt tagcaatgtg cctgttaaaa
    70261 ttacgcatga caaaggcgtc tttgaaggtc aagtttctat gatttttgca gctattacca
    70321 attctgttgg gggatttgaa atgattgctc ctgatgcaaa actagatgac ggtatgttta
    70381 cgctcatttt aataaagaca gcaaatcttt ttgaaattgt acatcttttg cgtttgattt
    70441 tggatggtgg taagcatatt acagatcgcc gtgtcgaata cattaagacc agtaaaatag
    70501 tcattgaacc ccaatgtggt aagcgaatga tgattaattt agatggtgag tacggaggag
    70561 atgctccaat tacattagag aacctaaaaa atcatatcac tttttttgca gatactgatt
    70621 tgatttctga tgacgcttta gtcttagatc aggacgaatt ggaaattgag gaaatcgcaa
    70681 agaaatttgc tcatgaagta gaagacttag aacaagaatt agaagaataa tacaatagtt
    70741 attagctact gacagtttag tcaaatgcac tactattaga atctaagatt tttaaatcaa
    70801 ttgaggtagt gttttttgat gcactcaaag agtcaattta ttcatatgag gggcccattt
    70861 gaggtctctc ttttttgatc atatgcaaga aaatgccatg ttttaggggt gttattatac
    70921 cctttttgga atcttgttgc ctttttgtta taataagagt gtaattctat ttttaaaaag
    70981 atcttaacaa agacagactc gtttatcaaa aaggttagta ttagtctaag aaagcgtact
    71041 cagtctaaag aaatctgttg acattcttaa ttttaaggaa tagaatagca aagtaaaaaa
    71101 aatttaaagg agtattctac tatgaatcct attttcgcat tggctttggc ctgttttggt
    71161 gtttctcttg ccgaaggttt cttgatggca aatcttttta aagcagcatc tcgccaacca
    71221 gaaatcattg gccaattacg ttcattaatg atcttgggtg ttgcctttat cgaaggtact
    71281 ttctttgtta cccttgttat ggccttcatt cttaaataac agcctatttg ataatagaaa
    71341 aggagggtgt tagatggaag aagctaaaat acccatgcta aagcttggtc caataacctt
    71401 taatttgacc ctacttgctg tttgtattgt cacaattgct gttatctttg cctttgtttt
    71461 ttgggcaagt cgccaaatga aattgaaacc agaagggaag caaactgctt tagaatattt
    71521 aatcagtttt gtggatggta ttggagaaga gcacttagat cataatctac aaaaatctta
    71581 ttcgctgtta ctctttacca tttttctctt tgtggctgtc gctaataatt tagggttatt
    71641 tactaagtta gagacagtta atggctataa cctatggacc tcgccaacag ccaatctggc
    71701 ttttgacctt gctctatctc tttttattac cttaatggta cacattgaag gggttagacg
    71761 tcgtggcttg gttgcccatt tgaaacgttt ggctacaccg tggccaatga ctccgatgaa
    71821 tttattagaa gagttcacaa atttcttatc acttgccatt aggttattcg gtaatatctt
    71881 tgccggggaa gttgttacag gtttgattgt tcaactggcc aattatcgag tttattggtg
    71941 gccgatcgct ttcctagtca atatggcgtg gacagccttt tcagtcttta tttcctgcat
    72001 acaggctttt gttttcacaa aactaacagc gacctatcta ggaaagaaag ttaatgaatc
    72061 agaagaataa ggaaggagaa caaacgaatg tcaatcacat ttggtgaact cgttgggaat
    72121 tttattctag taacaggttc tgtaatcgtc ttgttactct tgatcaaaaa attcgcttgg
    72181 ggtgcaattg aatcgatttt acagacacgc tcacaacaaa tctctcgaga tattgatcag
    72241 gctgagcaat cacgtctaag tgctcaacag ttagagacaa aaagtcaagc taacctagat
    72301 gctagtcgtt cacaagcaag taaaatcatt agtgatgcca aagaaattgg tcaattacaa
    72361 ggtgataaat tggtggcaga agctactgat gaagcaaaac gcttgaaaga aaaagcgttg
    72421 acagatattg aacaaagcaa atcagacgct atttcagcag tcaaaacaga aatgtctgat
    72481 ttaacggttc ttttagcgga aaaaattatg ggagccaatc ttgataagac ggcgcaaagc
    72541 cagcttattg acagttatct tgatgactta ggagaagctt aatgaccaaa aaagaacagg
    72601 ctcttatcga gcaatatgca aaaagccttg ttgaggtagc aagtgaacat cattctcttg
    72661 atgccttaca agctgatgtg cttgcgattt tagagacgtt tgtaacaact aatcttgatc
    72721 aaagtctatc aagtctagct gttccgcatg ctgaaaaaat aaaattgcta accttattaa
    72781 agggaaataa ttctgtttat atgaataatt tcttgaatct cattttacaa aacgaacgtg
    72841 aagcttattt gtatcaaatg cttcagactg ttttaaatga aattgcaata gtttcaaatc
    72901 agtatgatgt gactgttacc tcatcactac ctttgactga ggagcaaaaa agccgtgttc
    72961 gagcagttgt tgcaaagaaa tttgctgtaa cagcgggtcg tttaattgaa aaagtagatc
    73021 cttcgcttat tggaggattt attatcagcg tcaataataa agtaattgat accagtattc
    73081 gtcgtcaatt gcaagcattt aaaatgaatt taaaatagaa agtggtgtga cttttggcaa
    73141 ttaatgcaca agaaattagc gctttaatta aaaagcaaat tgagaacttc cagccaaatt
    73201 tcgatgtcac agaaactggg atcgttacct atattggtga cggtattgca cgtgcccgtg
    73261 gattagataa tgccatgagt ggtgaacttc ttgaatttga aaatggtgcc tatgggatgg
    73321 ctcaaaacct tgagtcaaat gatgtaggta ttattattct tggtgatttt tcagcaatcc
    73381 gtgaaggaga tgtggttaag cgcaccggta aaatcatgga agtaccagtt ggtgaagctc
    73441 tcattggacg tgtggtaaac ccacttggac aaccagttga tggcttggga gatattgaaa
    73501 caactggctt tagaccagtc gaaacgccag ctcctggtgt tatgcagcgt aaatccgttt
    73561 ctgaaccctt acaaactgga ttaaaagcaa ttgatgcttt ggttccaatt ggtcgtgggc
    73621 aacgtgagtt aattatcgga gaccgtcaga caggaaaaac atccgtagct attgatgcga
    73681 ttttgaacca aaaaggtcaa gacatgattt gtatctatgt ggctattggt caaaaagaat
    73741 caaccgttcg tacacaagtt gaaacccttc gccgttacgg tgccttggat tatactattg
    73801 ttgtgacagc gtcagcctca caaccatcac cattgctctt catcgctcct tatgcgggtg
    73861 ttgccatggc tgaagaattt atgtaccaag gcaagcatgt cttgattgtc tatgatgatt
    73921 tatcaaaaca agcggtggct tatcgtgaat tgtctctctt gcttcgtcgt ccaccaggtc
    73981 gtgaagctta cccaggggat gttttctact tgcatagccg tcttttggaa cgctctgcaa
    74041 aagtttctga tgatttaggt ggaggttcta tcacagctct accatttatc gaaacacagg
    74101 ccggagatat ctctgcatat attgcgacta atgttatttc gattacagac ggacaaatct
    74161 tcttgcaaga gaacctcttt aattcaggaa ttcgtccagc gattgatgca ggatcatctg
    74221 tctcacgtgt aggtggttca gctcaaatta aagcgatgaa aaaggttgct ggtactcttc
    74281 gtttggattt ggcttcctat cgtgaattag aagcctttac ccaatttggt tcggaccttg
    74341 atgctgcaac acaagcaaaa cttaatcgtg gtcgccgtac ggttgaaatc ttgaagcaac
    74401 cattgcataa accgttacct gttgaaaagc aagttgttat tctttatgcc cttactcatg
    74461 gtttcttaga tgatgttcct gtagatgata ttttggcttt tgaagaagct ctttacgact
    74521 actttgacgt tcattacaat gatttatttg aaactatccg taccacaaaa gaccttcctg
    74581 aagaagctgc ccttgatgcc gctattaaag cgtttaaaga acactcaaac tttaagtcat
    74641 agagggagga tactagtatg gcaggctctc taagtgaaat taaagctaaa attatttcaa
    74701 ctgagaaaac aagtaaaatc actagtgcca tgcgtatggt ttcttctgca aaacttgtta
    74761 aatctgagca agcagctcgt gattttcaaa tttacgcctc aaaaattcgc cagattacta
    74821 cagatttatt gaaatcagaa ttaaccatag gatctgataa tccgatgttg gtgtctcgtc
    74881 ctgtcaaaaa aacaggctat attgtcatca cgtctgataa aggacttgtt ggaggttaca
    74941 attcaaaaat cttgaaatct gttatggata tgattacaga gtaccatgct gatggtgact
    75001 atgaaatcat ttctattggt agtgttggtt cagacttctt caaagcaaga gggatgaatg
    75061 tggcttttga acttcgtgga cttgcggatc aaccaagttt tgaacaagtg agacaaatca
    75121 tttcacaatc cgttgacatg tttgtcaatg agatttttga tgagttatat gtctgttaca
    75181 atcaccatgt gaatagctta accagccaag tccgtgttca acagatgttg ccaatttctg
    75241 acttggttgc tgatgaagca gcagaagaag gtgttactgg gtttgaattg gaacctaatc
    75301 gtcatgatat tttagatcaa ttgttacctc aattcacaga aagtttaatt tatggggcta
    75361 tcattgatgc taaaacggct gaacatgcag caggtatgac tgctatgcag acagcgacag
    75421 ataacgctaa gaatgtcatt aacgatttga ccatccaata taaccgagct cgtcaagcag
    75481 caattacaca agaaattact gaaattgttg caggagcaaa tgcactagaa taaaaaataa
    75541 cgctgactag cgattaggtt attgtcagca ttcaatttta tcaatcgaga taaaatgact
    75601 tatgggactt ttctattgaa agactgctct tttcagtata aaagaagtta gcaagactaa
    75661 ctaagccctg actatcgaat ataaggagaa atgaatgagc tcaggcaaaa ttgctcaggt
    75721 tgttggtcca gtagtagacg ttatgtttgc tagtggggac aaacttccag agattaataa
    75781 tgcattgatt gtttataaag atagtgataa aaagcaaaaa atcgtccttg aagttgctct
    75841 ggaacttggt gacggtatgg tgcgaacaat cgctatggaa tcaactgatg ggcttacacg
    75901 tgggttagaa gttcttgaca ctggtcgtgc gattagcgta ccagtaggta aagaaacttt
    75961 gggacgcgtc tttaatgtac ttggagaaac cattgatttg gaagaaccat ttgcagaaga
    76021 tgttgaccgt cagccgatcc ataaaaaagc accatcgttt gatgagttat caacatcatc
    76081 agaaattctt gaaactggta tcaaggtaat tgaccttctt gccccttacc ttaaaggtgg
    76141 taaagttgga ctttttggtg gtgccggagt tggtaagact gtccttatcc aagaattaat
    76201 ccacaatatc gcccaagaac acggaggtat ttcagtattt accggtgttg gtgagcgaac
    76261 acgtgaagga aatgaccttt actgggaaat gaaagaatca ggcgttattg agaaaactgc
    76321 catggttttt ggtcagatga atgagccgcc tggggcacgt atgcgtgtag cccttactgg
    76381 tttaaccatt gctgagtatt tccgtgatgt agaaggccaa gatgttttgc tctttattga
    76441 taatatcttc cgtttcactc aggcaggttc agaagtatca gccctcttag gccgtatgcc
    76501 ttctgctgtt ggttaccaac caacacttgc tactgaaatg ggacaattgc aagaacgtat
    76561 tacgtcaact caaaaaggat ctgttacttc tatccaagcg atttatgtgc cagccgatga
    76621 ctatactgac ccagcgccag caactgcatt tgctcacttg gattcaacaa ctaaccttga
    76681 acgtaaattg actcaaatgg gtatttaccc tgcggttgac ccattggctt caagttcacg
    76741 ggccttatca cctgaaattg ttggtgaaga gcactatgct gtggcaacag aagttcaacg
    76801 tgtgcttcaa cgctaccgtg aattacaaga catcatcgct attttgggga tggatgaatt
    76861 atcagatgaa gaaaaaacat tggttggacg tgcgcgtcgt atccagttct tcctctcaca
    76921 aaattttaac gttgctgaac aatttaccgg tcttcctggt tcttacgtgc cagttgctga
    76981 gacagttcgc ggctttaaag aaattcttga aggaaaatac gatcaccttc cagaagacgc
    77041 ctttcgttca gttggtccaa ttgaggatgt gattaaaaaa gccgaaaaaa tgggctttta
    77101 gtgaggtgat gccatgacac aaatgactgt tcaagtggta acgccagatg gaatcaaata
    77161 tgatcaccat gctaaatgta tttctgtaac aacaccagat ggggaaatgg gtattttacc
    77221 taaccacatc aatttaattg cacccttgca agtccatgaa atgaaaattc gccgaggtgg
    77281 tgaagatgaa aaagtggact ggattgctat caatggtggt attattgaaa tcaaagataa
    77341 tgtggttacc gttgtcgctg attctgcaga acgtgaccgt gatatcgatg tcagccgagc
    77401 agagcgagca aaactaagag cagaacgtga aattgcacag gctgaaacga cccacaacat
    77461 tgatgaagtt cgtcgtgcca aagttgcctt gcgccgcgct ttgaatcgta tcaacgttag
    77521 taaaaaataa gtggtgttga taaaagacaa ggataagtaa gaaaggtttt taacctatta
    77581 ttttgtttgc tgagtctttt taacatcagt ttctgagagt ttgaccatac taccttctct
    77641 aaacacgtta ttattgttga gaggagttat atgggggaac tcttttttgt atccacgttg
    77701 ttagtagaaa ctcagtaatg acgcttaatg tatttttagg ctatcaactt agtcagagaa
    77761 gatgtcaact taattgataa gttggacgga tcaagatggt atgttataat aatcctatgg
    77821 aattattaat gaagatcatt gccttttcgt gtcatttatt ttttattggc cttagttacc
    77881 aattactgat tagtgtgatt gactggacaa aatttagtca ttatcatcca gaaaatcttg
    77941 gccggctacg actttttgtc tttttattag ccactgccct agggtatttg gtgagccatt
    78001 gtatgctgga attgattcaa attagccaga tgctcttttt tgagttccgc taatactgga
    78061 ataaaagaag tatggtataa ttttactacg actaagagat agataaggga gaaaattgtg
    78121 gataaaataa tcattgaagg tggtcaaaca cgcttagaag gagaagttgt tattgagggt
    78181 gctaaaaacg cagttcttcc tttactggca gcatctattt taccttcaaa aggaaaaaca
    78241 attcttagaa acgttcctat tctatctgat gtttttacta tgaataacgt ggtacgtggt
    78301 ttagatattc gtgttgactt taatgaagca gctaacgaaa tcacagttga tgcctcagga
    78361 cacattttag atgaagcccc ttacgagtac gtgagccaaa tgcgtgcctc tattgttgtt
    78421 ttaggaccaa ttttggcacg taatggccac gcaaaagtat caatgcctgg aggctgtacg
    78481 attggcagta ggcctattaa tttgcactta aaaggattag aggctatggg ggcaacgatt
    78541 actcaaaaag gtggagatat taccgctcaa gcagatcgac tgcaaggtgc catgatttat
    78601 atggacttcc catctgtagg agctacccaa aacttaatga tggctgccac tttag
//
LOCUS       DAXMQE010000004        75804 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.004, whole genome shotgun sequence.
ACCESSION   DAXMQE010000004 DAXMQE010000000
VERSION     DAXMQE010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 75804)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 75804)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..75804
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.004"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            complement(<1..226)
                     /locus_tag="ACF4ZO_000274"
     CDS             complement(<1..226)
                     /locus_tag="ACF4ZO_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HFD5485857.1"
                     /translation="MFYTIEELVKQADQQFNGNIAELMIATEVEMSGRNREDIIKIMS
                     RNLQVMKAAVTEGLTSTKSISGLTGGDAVKM"
     gene            complement(238..909)
                     /gene="sdaAB"
                     /locus_tag="ACF4ZO_000275"
     CDS             complement(238..909)
                     /gene="sdaAB"
                     /locus_tag="ACF4ZO_000275"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006565 - L-serine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HFD5485858.1"
                     /translation="MNTQKFQSVFDIIGPVMIGPSSSHTAGAVRIGKVVHSIFGDIPD
                     EVTFHLYNSFAKTYRGHGTDKALVAGIMGMDTDNPDIKNSLEIAHQKGIKIYWDILKD
                     SNAPHPNTVKISVKKADKTLSVTGVSIGGGNIQVTELNGFSVSLSMNTPTIVTVHKDI
                     PGMIAKVTDILSSNNINIATMNVTRESAGEKATMIIEVDSRECQEAANQIAKIPHIYN
                     VNFFD"
     gene            1207..2328
                     /gene="mnmA"
                     /locus_tag="ACF4ZO_000276"
     CDS             1207..2328
                     /gene="mnmA"
                     /locus_tag="ACF4ZO_000276"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016783 - sulfurtransferase activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HFD5485859.1"
                     /translation="MTDNSKIRVVVGMSGGVDSSVTALLLKEQGYDVIGVFMKNWDDT
                     DEFGVCTATEDYKDVAAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMTLGADYVATGHYAQVKRDENGTVHMLRGADNGKDQTYFLSQLS
                     QEQLQKTLFPLGHLQKSEVREIAERAGLATAKKKDSTGICFIGEKNFKQFLSQYLPAQ
                     KGRMMTIDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNQPWFVVGKDLSQNILYVGQ
                     GFYHEALMSNSLDASVIHFTREMPEEFTFECTAKFRYRQPDSQVTVHVRGDKAEVVFA
                     EPQRAITPGQAVVFYDGKECLGGGMIDMAYKNGQPCQYI"
     gene            3133..5031
                     /gene="mnmG"
                     /locus_tag="ACF4ZO_000277"
     CDS             3133..5031
                     /gene="mnmG"
                     /locus_tag="ACF4ZO_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002098 - tRNA wobble uridine modification
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HFD5485860.1"
                     /translation="MTHEFTESYDVIVIGAGHAGVEASLATSRMGCKTLLATINLDML
                     AFMPCNPSIGGSAKGIVVREIDALGGEMGKNIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KSLYAREMKHTVEKQANLTLRQTMIDDILVEDGRVVGVLTATGQKFAAKAVVVTTGTA
                     LRGEIILGELKYSSGPNNSLASVTLADNLKKLGLEIGRFKTGTPPRVKASSINYDQTE
                     IQPGDDKPNHFSFMSKDADYLKDQIPCWLTYTNQTSHDIINQNLYRAPMFSGIVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRDTEEVYVQGLSTSLPEDVQKDLIHSIKGL
                     EKAEMMRTGYAIEYDIVLPHQLRATLETKLISGLFTAGQTNGTSGYEEAAGQGLIAGI
                     NAALKVQGKSELILKRSDAYIGVMIDDLVTKGTLEPYRLLTSRAEYRLILRHDNADMR
                     LTEIGRDIGLVDDERWKAFEIKKNQFDNELKRLNSIKLKPVKATNDRVQELGFKPLTD
                     AMIAKEFMRRPEIDYATAVSFVGPAAEDLDAKIIELLETEIKYEGYIRKALDQVAKMK
                     RMEEKRIPANIDWDAIDSIATEARQKFKKINPETIGQASRISGVNPADISILMIYLEG
                     NGKAHRKY"
     gene            5121..7097
                     /locus_tag="ACF4ZO_000278"
     CDS             5121..7097
                     /locus_tag="ACF4ZO_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HFD5485861.1"
                     /translation="MKKFRFETIHLIMMGLILFGLLALCVSIMQSKILILLAIFLVLL
                     FVVALLWYQKEAYQLSDLAHIELLNEQTEDNLKTLLDNMPVGVVQFDQETNAVEWYNP
                     YAELIFTTEEGFIQNSLIQQIITEKRREDISQTFEVSGNKYTSYIDVSSGIFYFFDSF
                     VGNRQLADASMLRPVVGIISVDNYDDITDDLSDADTSKINSFVANFIDEFMESKRIFY
                     RRVNMDRYYFFTDFKTLNDLMDNKFSVLEEFRKEAQDAQRPLTLSIGISFGEENHSQI
                     GQVALENLNIALVRGGDQIVIRENADHTNPIYFGGGSVSTVKRSRTRTRAMMTAISDR
                     IKMVDNVFIVGHRKLDMDALGSAVGMQFFAGNIIENSFAVYNPDEMSPDIERAIERLQ
                     ADGKTRLISVSQAMGLVTPRSLLVMVDHSKISLTLSKEFYEQFQNVIVVDHHRRDDDF
                     PDNAILTFIESGASSAAELVTELIQFQNAKKRLNKIQASVLMAGIMLDTKNFSTRVTS
                     RTFDVASYLRSKGSDSVEIQNISATDFEEYKQINEIILQGERLGDSIIVAAGEKNHLY
                     SNVIASKAADTILSMAHVEASFVLVETASHKIAISARSRSKINVQRVMEKLGGGGHFN
                     LAACQLTDISLPQAKHLLLKTINMTLKETGEVES"
     gene            7094..7546
                     /gene="rplI"
                     /locus_tag="ACF4ZO_000279"
     CDS             7094..7546
                     /gene="rplI"
                     /locus_tag="ACF4ZO_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HFD5485862.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVLTGYAQNFLIKKNLAKEATSQSI
                     GELKGKQKAEEKAQAEILAEAQAVKAVLDEDKTRVQFQEKVGPDGRTFGSITAKKISE
                     ELQKQFGVKVDKRHIVLDHPIRAIGLIEVPVKLHKEVTAEIKLAITEA"
     gene            7576..8943
                     /gene="dnaB"
                     /locus_tag="ACF4ZO_000280"
     CDS             7576..8943
                     /gene="dnaB"
                     /locus_tag="ACF4ZO_000280"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HFD5485863.1"
                     /translation="MRLPEVAELRVQPQDLLAEQSVLGSIFISPDKLIAVREFISPDD
                     FYKYAHKIIFRAMITLSDRNDAIDATTIRTILDDQDDLQSIGGLSYIVELVNSVPTSA
                     NAEYYAKIVAEKAMLRDIIARLTESVNLAYDEILKPEEVIAGVERALIELNEHSNRSG
                     FRKISDVLKVNYEALEARSKQTSNVTGLPTGFRDLDKITTGLHPDQLVILAARPAVGK
                     TAFVLNIAQNVGTKQKKTVAIFSLEMGAESLVDRMLAAEGMVDSHSLRTGQLTDQDWN
                     NVTIAQGALAEAPIYIDDTPGIKITEIRARSRKLSQEVDGGLGLIVIDYLQLITGTKP
                     ENRQQEVSDISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDA
                     DIVAFLYRDDYYRKEGDDAEEAVEDNTIEVILEKNRAGARGTVKLMFQKEYNKFSSIA
                     QFEER"
     gene            8960..9232
                     /locus_tag="ACF4ZO_000281"
     CDS             8960..9232
                     /locus_tag="ACF4ZO_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HFD5485864.1"
                     /translation="MSDAFTDVAKMKKIKEDIRAHEGQLVELTLENGRKREKNKIGRL
                     IEVYSSLFIIEYSDSSDTPGAIDNSYVESYTYSDILTEKTLIRYLD"
     gene            9962..10573
                     /gene="rpsD"
                     /locus_tag="ACF4ZO_000282"
     CDS             9962..10573
                     /gene="rpsD"
                     /locus_tag="ACF4ZO_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HFD5485865.1"
                     /translation="MSRYTGPSWKQSRRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFSYGLGEKQFRNLFVQATKIKEGTLGFNFMVLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVDPGQVISVREKSMKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(10727..11260)
                     /locus_tag="ACF4ZO_000283"
     CDS             complement(10727..11260)
                     /locus_tag="ACF4ZO_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFD5485866.1"
                     /translation="MVNRKENTKQAILKAMVMLLKTESFDDITTVKLSKRAGISRSSF
                     YTHYKDKYEMIDYYQQTFFHKLEYIFEKKYQNKEQAFLEVFEFLQREQLLSSLLSANG
                     TKEIQAFIINKVRLLITTDLQDKFSTEELSQTEKEYQSIYLAHAFFGVCQSWIAKGKK
                     ESPQEMTQFVLKMLTST"
     gene            11395..13668
                     /locus_tag="ACF4ZO_000284"
     CDS             11395..13668
                     /locus_tag="ACF4ZO_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HFD5485867.1"
                     /translation="MLEELKTLIKNPKLMITMIGVALVPALYNLSFLGSMWDPYGRVN
                     DLPIAVVNHDKPAKRADKSLTIGNDMVDKMSKSKDLEYHFVSAKQAQEGLKEGDYYMV
                     ITLPEDLSQRAATLLNPEPQKLTIRYQTSKGHGMVAAKMGETAMAKLKESVSQNITKT
                     YTSAVFSSMTDLQSGLKEASAGSQALASGAKTAQAGSQTLSTNLAALTGASQQFQQGT
                     GRLTSGLTTYTDGVNQVKNGLGTLSTDIPNYLNGVSRLSQGASQLNQGLSQLTQATTL
                     SDEKAKGIQSLIVGLPVLNQGIQQLNTELSTLQPPNLNADELGNSLGAIAQAAKQVIA
                     EETAAQNEELSALQATSVYQSLTAEQQGELAAALSQSDKSQTVSAAQTILSSVQTLST
                     SLQSLSQEDQSKQLEQLKEAVAQIANQSNQALPGASSALTELSTGLAKVNGSLNQQVL
                     PGSNQLTTGLAQLNRYNTAIGSGVIKLSEGANALSSKSGELLDGSHQLSEGATKLADG
                     SSQLSQGGHQLTSGLTELSTGLSTLNGSLAKASQQLSLVSVTDKNAKAVAKPLVLNEK
                     DKDGVKTNGIGMAPYMIAVSLMVVALSTNVIFANSLSGRPVKDKWDWAKQKFVINGFI
                     STMGSIVLYLAIQLLGFEARYGMETLGFIMLSGWTFMALVTALVGWDDRYGSFASLVM
                     LLLQVGSSGGSYPIELSGAFFQKLHPFLPMTYVVSGLRQTISLSGHIGVEVKVLTGFL
                     LAFMVLALLIYRPKKTV"
     gene            complement(13784..14857)
                     /locus_tag="ACF4ZO_000285"
     CDS             complement(13784..14857)
                     /locus_tag="ACF4ZO_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat-containing
                     protein"
                     /protein_id="HFD5485868.1"
                     /translation="MKNISRKCFMTSVVCIILGGILLGAGYATGGLQDIKHQTTPKKV
                     IKTFDQITALDIDSSASTITVETGPVQRPTVTYYTHPKLIDPIVTTVTGKTLSLSQKP
                     KDVVITGGIEILGFTLNNSRQEKNYRSITITVPEKTSLNEVKASNVPHTTLSNLTVQD
                     MQFDGNLTLLYTKVKKATITGMLEATKSQLTNLELKADYSFSNLTDSSVENGTISLGH
                     GQLTTKNTNLKSVTIQSLSPGGVEAEETSLENVTFTVTSEQENEETNDNGAIFTAHSL
                     TLKGTNTISGGDVAVDITLTNPKTTAYKTKTEDGKISLGSQLTPAKIGKESTSDVISY
                     VAENKAATGNLTVNLNKGDITIK"
     gene            complement(14854..15441)
                     /locus_tag="ACF4ZO_000286"
     CDS             complement(14854..15441)
                     /locus_tag="ACF4ZO_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HFD5485869.1"
                     /translation="MTRTEYLAELDKYLRKLPREDYHEAMEYYIEYFDEAGPDKESQV
                     IDDLGNPKEAASEIISNVLGKHLATPEKTPKNRATIIGLTILSLFAAPIALPVLLALI
                     LFIIASLMLGLTAIFAAYIFGLAGILVAGVTLFESLTLIGSSIPAQAMGIGSALLCFG
                     GGLLIWIIATAILRFSGRAFVAFIKWISNKKGAQA"
     gene            complement(15428..15754)
                     /locus_tag="ACF4ZO_000287"
     CDS             complement(15428..15754)
                     /locus_tag="ACF4ZO_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HFD5485870.1"
                     /translation="MYFPVSATLIEFLILAIVEKNDSYGYDISQTIKLVANIKESTLY
                     PILKKLEKAGFLTTYSQEHQGRKRKYYAVTSSGRAQLIFLKKEWQSYKFALDGIIEGS
                     LRHDKD"
     gene            15961..16602
                     /locus_tag="ACF4ZO_000288"
     CDS             15961..16602
                     /locus_tag="ACF4ZO_000288"
                     /EC_number="3.6.1.55"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005777 - peroxisome [Evidence IEA];
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003986 - acetyl-CoA hydrolase activity
                     [Evidence IEA];
                     GO_function: GO:0008413 - 8-oxo-7,8-dihydroguanosine
                     triphosphate pyrophosphatase activity [Evidence IEA];
                     GO_function: GO:0010945 - coenzyme A diphosphatase
                     activity [Evidence IEA];
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_function: GO:0035539 - 8-oxo-7,8-dihydrodeoxyguanosine
                     triphosphate pyrophosphatase activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0009132 - nucleoside diphosphate metabolic
                     process [Evidence IEA];
                     GO_process: GO:0015938 - coenzyme A catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CoA pyrophosphatase"
                     /protein_id="HFD5485871.1"
                     /translation="MKDLLKQYQAKPLGEEKRYAVFLPLILVNDDWHVLYEVRSQHIS
                     QPGEVSFPGGQVENQETLQEAAIRETVEELTVDASQIQLWGEIDYLVQSSRTIHCFVG
                     QLVVDDWKSIEANEEVDRLFTVPLQQLLATEPVFYHLEASPLKTSDFPFDRIRHGKDY
                     QFSQQYRSIPFYENLEETIWGMTAQFTKCLTDILNDESIAKKNPLDIEKSKGR"
     gene            complement(16649..17491)
                     /locus_tag="ACF4ZO_000289"
     CDS             complement(16649..17491)
                     /locus_tag="ACF4ZO_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HFD5485872.1"
                     /translation="MVSFISRVFKGMIIALGFILPGVSGGVLAAILGIYERMISFLAH
                     MRDSFIENVLFFLPVGIGGILGIALFSFPVEFLLKHYQVSVLWGFAGAIVGTIPSLIK
                     ESTKQSHRDKADWLWLVFTFVISGLGLYFLNDLIGTLPANFLTFILAGALIALGVLVP
                     GVSPSNLLLILGLYGPMLIGFKSLDLLGTFLPIAIGGVLAILAFSKSMDYALQHHHSK
                     VYHFIIGIVLSSTLLILIPNSSSPESISYSHAGILTWLMAVVLFALGIWLGLWMSQLE
                     EKYK"
     gene            17930..18226
                     /locus_tag="ACF4ZO_000290"
     CDS             17930..18226
                     /locus_tag="ACF4ZO_000290"
                     /inference="COORDINATES: protein motif:HMM:NF013540.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HFD5485873.1"
                     /translation="MQNLLMLSKSLQVPLEQLIAEDIPKMTLIIKDEEIKQCDRNTHI
                     MLFGTLLIAISIYPIMSWLGWWGYGPVAILWLIIMRSALRIERFKKTYDVQTYR"
     gene            complement(18702..19304)
                     /locus_tag="ACF4ZO_000291"
     CDS             complement(18702..19304)
                     /locus_tag="ACF4ZO_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003039416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5485874.1"
                     /translation="MTTKTYFMRSFNLILYLLLIAPICYVFGWLFNLVSVQLSTVTFV
                     NLDTVKNVTDTISSVCYGFALISLLLALLSGLKMIQRLNTDSLGNYCQSIYRTFLLRH
                     FLFQRERVQEVSNFEHQTVTTINPIHNGFNRAVRKCIVDIRKDAITVFLKVPRDQQGQ
                     KILKDTGVQLKEEIVIQHTDYYFSSPVRVRNQLWFIGQKR"
     gene            complement(19301..20130)
                     /locus_tag="ACF4ZO_000292"
                     /pseudo
     CDS             complement(19301..20130)
                     /locus_tag="ACF4ZO_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203861.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(20130..21041)
                     /locus_tag="ACF4ZO_000293"
                     /pseudo
     CDS             complement(20130..21041)
                     /locus_tag="ACF4ZO_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000667635.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
     gene            complement(21085..21423)
                     /gene="cadX"
                     /locus_tag="ACF4ZO_000294"
     CDS             complement(21085..21423)
                     /gene="cadX"
                     /locus_tag="ACF4ZO_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cd(II)/Zn(II)-sensing metalloregulatory
                     transcriptional regulator CadX"
                     /protein_id="HFD5485875.1"
                     /translation="MKKDNICQVNVINQQNVTTATNYLEKEKVQKSLRILSKFTDNKQ
                     INIIFYLLAVEELCVCDIACLLNLSMASASHHLRKLANQNILDTRREGKIIYYFIKDE
                     EIRDFFNQLG"
     gene            complement(21435..22049)
                     /locus_tag="ACF4ZO_000295"
     CDS             complement(21435..22049)
                     /locus_tag="ACF4ZO_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HFD5485876.1"
                     /translation="MIQNVVTSIILYSGTAVDLLIILMLFFAKRKSRKDIINIYLGQF
                     LGSVSLILLSLLFAFVLDYIPSKEILGLLGLIPIFLGLKVLLLGDSDGEAIAKEGLSK
                     DNKNLIFLVAMITFASCGADNIGVFVPYFTTLNLANLIVTLLTFLVMIYLLVFSAQKL
                     AQVPSVGETLEKYSRWFIAVVYLGLGIYILIENNSFDMLWTVLG"
     gene            22078..22302
                     /locus_tag="ACF4ZO_000296"
     CDS             22078..22302
                     /locus_tag="ACF4ZO_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002892741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FanG protein"
                     /protein_id="HFD5485877.1"
                     /translation="MNFNIKLCRCQFQLHQNIDKELVYQILKSPAIEMITGLNFNIQM
                     IDSSKKGRVKGRVLIDLYCNVMNFKNSKIA"
     gene            complement(22342..22491)
                     /gene="rpmG"
                     /locus_tag="ACF4ZO_000297"
     CDS             complement(22342..22491)
                     /gene="rpmG"
                     /locus_tag="ACF4ZO_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HFD5485878.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVT
                     FTEVK"
     gene            complement(22507..22689)
                     /gene="rpmF"
                     /locus_tag="ACF4ZO_000298"
     CDS             complement(22507..22689)
                     /gene="rpmF"
                     /locus_tag="ACF4ZO_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HFD5485879.1"
                     /translation="MAVPARHTSKAKKNKRRTHYKLTAPSVQFDETTGDYSRSHRVSL
                     KGYYKGRKIAKANEAK"
     gene            22909..24189
                     /gene="hisS"
                     /locus_tag="ACF4ZO_000299"
     CDS             22909..24189
                     /gene="hisS"
                     /locus_tag="ACF4ZO_000299"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004821 - histidine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006427 - histidyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HFD5485880.1"
                     /translation="MKLQKPKGTQDILPGDAAKWQYVESVARDTFSQYNYGEIRTPMF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PVKLYYIGSMFRYERPQAGRLREFHQIGVECFGAANPATDVETIAMAYHLFEKLGIKD
                     VTLHLNSLGSPESRAAYRQALIDYLTPMRDQLSKDSQRRLDENPLRVLDSKEKEDKLA
                     VEKAPSILDYLDEESQAHFEAVKDMLEALDIPYVIDTNMVRGLDYYNHTIFEFITSVE
                     GSDLTICAGGRYDSLVGYFGGPETPGFGFGLGLERLLMVIEKQGITLPIETEMDVYLA
                     VLGDGANSKALELVQAIRRQGFTAERDYLGRKIKAQFKSADTFKAKLVMTLGESEVEA
                     GKAVIKNNRSRQEVEVSFEDMMTNFANISEQLLS"
     gene            24527..26275
                     /gene="aspS"
                     /locus_tag="ACF4ZO_000300"
     CDS             24527..26275
                     /gene="aspS"
                     /locus_tag="ACF4ZO_000300"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HFD5485881.1"
                     /translation="MKRSMYAGRVREEHIGTTITLKGWVSRRRDLGGLIFIDLRDREG
                     VMQLVINPEEVSSDVMATAERLRSEYVIEVEGFVEARQQANDKLATGMVELKVSALTI
                     LNTAKTTPFEIKDDVEVSDDTRLRYRYLDLRRPEMLENFKLRAKVTHSIRNYLDDLEF
                     IDVETPMLTKSTPEGARDYLVPSRVSQGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLSEQEIQDIVEGMIAKVMKETKEIDVTLPFPRMSY
                     DVAMNSYGSDKPDTRFEMLLQDLTVTVKGIDFKVFSEAPAVKAIVVKGNADRYSRKDI
                     DKLTEFAKQFGAKGLAWVKVTDGQLAGPVAKFLTAIETELSSQLKLAENDLVLFVADT
                     LEVANNTLGALRNRIARDLDMIDQSQFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPT
                     PESAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKEMQERMFKALGFTADEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAEEDNIREVIAFPKNNKASDPMTQAPSLV
                     SENQLEELSLQIESHD"
     gene            26268..27209
                     /locus_tag="ACF4ZO_000301"
     CDS             26268..27209
                     /locus_tag="ACF4ZO_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFD5485882.1"
                     /translation="MIKKTTYKKKVKYVISRGAKKVGLLHALRSISREKYAEKISASL
                     LYGILSSIAVNFFFQPGHVYSSGATGLAQVFSALSHRLLGCDFPIAFAFYLINIPLLI
                     LAWYKIGHQFTIFTFITVSMSSFFIQIMPQVTLTTDPLINAIFGGLVMGMGIGTGLKS
                     RISSGGTDIVSLTLRKRTGKDVGSLSLMVNGAILAFAGILFGWQYALYSMVSIFVSSR
                     VTDAIFTKQKKMQATIITSHPERVIHMIHKRLHRGVTSINDAEGTYKHEQKAVLITIL
                     TCEEYPEFKWLMLKTDPQAFVSVAENVRIIGRFVEDD"
     gene            27229..28107
                     /locus_tag="ACF4ZO_000302"
     CDS             27229..28107
                     /locus_tag="ACF4ZO_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFD5485883.1"
                     /translation="MSIDQRLQLKKFCFIILGAAIYAFAFVYFYMANRIAANGLAGLT
                     LVGKALFEIDPSLIGYLINLPLVLLGARCFGKRAMVYTVMGILSLYFFVWLFQRFPLV
                     VDLDHDNLVVSLMAGIIGGLGGGLVFRNGGTIGGADIIAKLLEDKLGLQLNQALLGID
                     LFVMIVSLTYISLPQMMYALIASFMYGQIVRLVQQGGYSARGIFIVSEQAEKIARFIM
                     EELGRGVTYLTGEGAYSGRRKKVIYVALGRRDIRELKAFLTQVDPNAFITYFDVNEVN
                     SPEFLTIKSKYHKKRK"
     gene            28150..29022
                     /locus_tag="ACF4ZO_000303"
     CDS             28150..29022
                     /locus_tag="ACF4ZO_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFD5485884.1"
                     /translation="MAHHDKLTKLLKLFLIALGVAIYTFGFVNFNMANALAEGGVAGI
                     TLILHAHFGINPAYSSLLFNLPLFILGAKIFGKRSLALTIYGTVLMSAFIWMWQKVPI
                     ELGLENDMMLVAVVAGLFSGIGSGIVFRYGATTGGTDIIGCIAEEKFGAKLGQTLLLV
                     DALVLTASLTYVDLKHMLYTLVTSFVFSQMISVVQNGGYTIRGMIIITKHSEAAAQAI
                     LTEINRGVTYLKGQGAYSGNDYNIMYVTLNPTEVREVKRILAGLDPDAFISIIDVDEV
                     ISSDFKIRRRNYDK"
     gene            complement(29049..29357)
                     /locus_tag="ACF4ZO_000304"
     CDS             complement(29049..29357)
                     /locus_tag="ACF4ZO_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HFD5485885.1"
                     /translation="MPSEKEILDALSKVYSEQVIQADDYFRQVIFELASQLEKEGMSS
                     LLATKIDSLINQYILTHQFDAPKSIFDLSRLVKTKASHYKGTAISAIMLGSFLSGGPK
                     "
     gene            complement(29445..31136)
                     /gene="argS"
                     /locus_tag="ACF4ZO_000305"
     CDS             complement(29445..31136)
                     /gene="argS"
                     /locus_tag="ACF4ZO_000305"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004814 - arginine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006420 - arginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HFD5485886.1"
                     /translation="MDTKTLIASEIAKVVPELEQDAIFNLLETPKNSDMGDLAFPAFS
                     LAKVLRKAPQMIASELAEQIDESQFEKVVAVGPYINFFLDKAKISSQVLEQVITAGSD
                     YAQQDEGQGRNVAIDMSSPNIAKPFSIGHLRSTVIGDSLAHIFAKMGYKPVKINHLGD
                     WGKQFGMLIVAYKKWGDETAVQAHPIDELLKLYVRINAEAETDPTVDEEAREWFRKLE
                     DGDKEATELWQWFRDESLLEFNRLYDQLHVTFDSYNGEAFYNDKMDEVLDLLEAKNLL
                     VESKGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKRTYDFAKSVYVVGNE
                     QAAHFKQLKAVLKEMGYDWSDDMTHVAFGLVTKGGAKLSTRKGNVILLEPTVAEAINR
                     AASQIEAKNPNLADKEAVAHAVGVGAIKFYDLKTDRMNGYDFDLEAMVSFEGETGPYV
                     QYAHARIQSILRKADFTPSATTTYSLADAESWEIIKLIQDFPRIIKRTSDNFEPSIMA
                     KFAINLAQSFNKYYAHTRILDDNSERDNRLALCYATATVLKEALRLLGVDAPNEM"
     gene            31427..31864
                     /gene="argR"
                     /locus_tag="ACF4ZO_000306"
     CDS             31427..31864
                     /gene="argR"
                     /locus_tag="ACF4ZO_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006525 - arginine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HFD5485887.1"
                     /translation="MNKMERQQQIKRIIQAEHIGTQEDIKNHLQKEGIVVTQATLSRD
                     LREIGLLKLRDEQGKLYYSLSEPVATPFSPEVRFYVLKVDRAGFMLVLHTNLGEADVL
                     ANLIDNDAIEDILGTIAGADTLLVICRDEEIAKRFEKDLAAGL"
     gene            31861..32214
                     /locus_tag="ACF4ZO_000307"
                     /pseudo
     CDS             31861..32214
                     /locus_tag="ACF4ZO_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053122.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
     gene            32201..34756
                     /gene="mutS"
                     /locus_tag="ACF4ZO_000308"
     CDS             32201..34756
                     /gene="mutS"
                     /locus_tag="ACF4ZO_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HFD5485888.1"
                     /translation="MAKTNISPGMQQYLDIKKDYPDAFLLFRMGDFYELFYDDAVKAA
                     QLLEIGLTSRNKNAENPIPMAGVPHHSAQQYIDVLIELGYKVAVAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSAKPDSANNFLVAVDFDGCRYGLAYMDVSTGEFCVTDLADFTS
                     VRSEIQNLKAKEVLLGFDLSEEEQTILVKQMNLLLSYEETVYEDKSLIDGQLTTVELT
                     AAGKLLQYVHKTQMRELSHLQALVHYEIKDYLQMSYATKSSLDLVENARTNKKHGSLY
                     WLLDETKTAMGMRLLRSWIDRPLVSKEAILERQEIIQVFLNAFIERTDLSNSLKGVYD
                     IERLSSRVSFGKANPKDLLQLGHTLAQVPYIKAILESFDSPCVDKLVNDIDSLPELEY
                     LIRTAIDPDAPATISEGSIIRTGFDERLDHYRKVMREGTGWIADIEAKERQASGINNL
                     KIDYNKKDGYYFHVTTSNLSLVPEHFFRKATLKNSERYGTAELAKIEGQMLEAREESS
                     SLEYDIFMCIRAQVETYINRLQKLAKILATVDVLQSLAVVAETNHYIRPQFNDNHVIT
                     IQEGRHAVVEKVMGVQEYIPNSISFDQQTSIQLITGPNMSGKSTYMRQLALTVIMAQM
                     GSFVAADHVDLPLFDAIFTRIGAADDLISGQSTFMVEMMEANQAIKRASDNSLILFDE
                     LGRGTATYDGMALAQAIIEYIHDRVGAKTIFATHYHELTDLSTKLTSLVNVHVATLEK
                     DGDVTFLHKIAEGPADKSYGIHVAKIAGLPKSLLKRADEVLTRLETQSRSTEIMSVPP
                     QVESSSAVRQGQLSLFGDEEKAHEIRQALEAIDVMNMTPLQAMTTLYELKKLL"
     gene            complement(35338..35943)
                     /locus_tag="ACF4ZO_000309"
     CDS             complement(35338..35943)
                     /locus_tag="ACF4ZO_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5485889.1"
                     /translation="MKKKLMLAVMLLTVGVATNVKAEEEDNAVSTSVENIHSKVFEVD
                     GEDSQKVIVAPFKVGDESIKLNIPNVPYGYVYASTTSTSNEKKEDKVEKPSAITVERE
                     CSALEKSKYSYGQECPKTTYQISGYRANGGGDYTVKLKSPLDTGDRVAIRIFDDGHDY
                     ITTKVYHIPVKEILSSRDVKRIKVNPKAPKLQNIHQELKIY"
     gene            complement(36144..36527)
                     /locus_tag="ACF4ZO_000310"
     CDS             complement(36144..36527)
                     /locus_tag="ACF4ZO_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family phage packaging/lysis
                     transcriptional regulator"
                     /protein_id="HFD5485890.1"
                     /translation="MSKKNAIRKLKEFHRWQRIANSLDLTYTELYQFDIEYHPTRRKH
                     LEISRECALEELNAIRYAINQLSKIEYRKILIECYLIGEKKPQQDIMEELKRSQSWYY
                     ETKKRALLEFVEFYRDGVLKNNVRL"
     gene            complement(36502..36864)
                     /locus_tag="ACF4ZO_000311"
     CDS             complement(36502..36864)
                     /locus_tag="ACF4ZO_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HFD5485891.1"
                     /translation="MSAKEQLKELKPLFALITLFEEQRDKDIKLINAFHNPEAIRHIE
                     KGTAKQLLYLAKERDKRLAMIATLQDERQIAVIKARYVDDLSWDEILDKLGYSRNTVF
                     KLHREALEVLDEQEERYS"
     gene            complement(37268..37756)
                     /locus_tag="ACF4ZO_000312"
     CDS             complement(37268..37756)
                     /locus_tag="ACF4ZO_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5485892.1"
                     /translation="MLELSIENIIKPMKTQGKTRVTGSIGDQAIRIDLDGLVIHYNGQ
                     GLLLETIPGTYGGKRYFFVCPDCERRCRKLFKASHAFACGSCQKVHQATLNRSKTDCC
                     YYWQLAFKECLKVNPEARHIHGYYSRDDFPKRPKYMRLTKYLYHWRRFHYYMDKGDRY
                     WL"
     gene            complement(37831..38340)
                     /locus_tag="ACF4ZO_000313"
     CDS             complement(37831..38340)
                     /locus_tag="ACF4ZO_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001258765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5485893.1"
                     /translation="MRTFSDTPKTFTFHYTFKDFDTAQVACHAILGYMTGTYEQPVID
                     ATYHNDDQGGHANQLVLKYAEDRKLSKVFKRICDSFKDYYNQPEDMTDEELDHQRVVS
                     LSKSTQGKVNNRDTLIAFISDHNQLAEHLSMNYKEMTPEDLGAILESISQAFNHLYDM
                     VVEDQLLVK"
     gene            complement(38342..38515)
                     /locus_tag="ACF4ZO_000314"
     CDS             complement(38342..38515)
                     /locus_tag="ACF4ZO_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001873750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5485894.1"
                     /translation="MKLKLHTRGGNTITIQGDRTLYNELIKYLLSGQQPNWVACPSAI
                     INLSDIIAITKEK"
     gene            complement(38521..38694)
                     /locus_tag="ACF4ZO_000315"
     CDS             complement(38521..38694)
                     /locus_tag="ACF4ZO_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2758 domain-containing protein"
                     /protein_id="HFD5485895.1"
                     /translation="MKIKLFYQKHNESLDDFEYRVNLFTLSVSVIDIKFSEATYGNYE
                     DMSTTTSLLVLYR"
     gene            complement(38981..40669)
                     /locus_tag="ACF4ZO_000316"
     CDS             complement(38981..40669)
                     /locus_tag="ACF4ZO_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003896 - DNA primase activity [Evidence
                     IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage/plasmid primase, P4 family"
                     /protein_id="HFD5485896.1"
                     /translation="MLKQNTEKEGRTIEQEDLKNLENEITEARENEDKYFSTFKGVRG
                     QLIKECQEMKDEAFKIAYDGVMADSKHLENVKAGRLTEVQHEELAKEKGQEASEKALP
                     KTPLGVAIMLKHYLRFIRVKPEAQGQKAPLYFFHPDHGVWLEDNEFLQDLISVIFPNA
                     TEKQAFDTLYKIARQSQLKEIQREYTVIGNQLYNYKTGQFEELTPDITVTRKIKTGYN
                     KKAKEPTIKGWKPTAWLLELFDGDAELYNLAIQIIKASITGQSLQKIFWLFGEGGTGK
                     GTFQQLLINLVGMDNVASLKITELAKSRFTTSILLGKSIVIGDDIQKDAVIKDTSDIF
                     SLATGDIMTIEDKGKRPYSIRLNMTVVQSSNGLPRMNGDKSAIDRRFRILPFTKVFKG
                     KPNKAIRNDYINRKEVLEYLLKLAIETPITDINPKASIEILEEHHKEMNPVIDFVSKF
                     FTDELTSEFIPNSFVYHVWKGFLEYYDIKQIKSERGLHKEIKSNLPEGFEAGQKVIPV
                     GRQLHTGFYPKEDLPLFASASYANGRASPEKRKKPKNERGYYNHWPTHKKQKKT"
     gene            complement(40638..41495)
                     /locus_tag="ACF4ZO_000317"
     CDS             complement(40638..41495)
                     /locus_tag="ACF4ZO_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001029300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase alpha helix C-terminal domain-containing
                     protein"
                     /protein_id="HFD5485897.1"
                     /translation="MTIYEARGFSSYLYPYKGQLEPFDYIAQFKPLKPPEDIDIEEYK
                     RTQAPYCLSGKVTAEKNGSYKRNNASLVYRDLIFLDYDEIETGVNLPKIVSETLWEYS
                     YIIYPTIKHTPEKPRYRLVMKPSDVMTEATYQQVVKEIADKIGLPFDLASLTWSQLQG
                     LPVTTGDPEDYQRYVNRGLDYPVPKNGSTPNRQVVTTYTPRPRSQRSITMRVIDTLFN
                     GFGDEGGRNVTLTKFVGLLFNKWVDCDLETAYELVQIANSVTTKPLPIDEIDRTFTSI
                     AKAEYRKRG"
     gene            complement(41496..41768)
                     /locus_tag="ACF4ZO_000318"
     CDS             complement(41496..41768)
                     /locus_tag="ACF4ZO_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5485898.1"
                     /translation="MSLFSQDYEAKLLEQNLTAFNRFLEAYQKPKPRVLGLITAEQVK
                     EELNIKGKTLKRWENAGLRRYQPPLEDTRKHYYKVSDILIFLGVNV"
     gene            complement(41771..42100)
                     /locus_tag="ACF4ZO_000319"
     CDS             complement(41771..42100)
                     /locus_tag="ACF4ZO_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000174495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5485899.1"
                     /translation="MTLPENYRRVLNLIKVGADNPITGAEISLILKLEERSVQSIISS
                     LITRYNIPIIGIRHGFNRGYFIPANKEELLDGAKAFYNQVQKEQERLSVLLNADLTSY
                     KELLKGG"
     gene            complement(42097..42459)
                     /locus_tag="ACF4ZO_000320"
     CDS             complement(42097..42459)
                     /locus_tag="ACF4ZO_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5485900.1"
                     /translation="MTTEEYFKKLLEDSEKQPTNWLSDRVLDKNIKMLDEDIEAEWDD
                     FPLFTKKIFINTTQRDYNKADAVVKFLESIPIEMEYKKGLNIVIQALNELKDSLKNQV
                     LGVIDNQILFPNDKEDTK"
     gene            complement(42472..42663)
                     /locus_tag="ACF4ZO_000321"
     CDS             complement(42472..42663)
                     /locus_tag="ACF4ZO_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5485901.1"
                     /translation="MQELNLTPTQTLILFFVLGLLGLLLSLSKSLIDIDLPEDTQVPK
                     PRQNANYGAYIQSQNHYYN"
     gene            complement(42663..42995)
                     /locus_tag="ACF4ZO_000322"
     CDS             complement(42663..42995)
                     /locus_tag="ACF4ZO_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5485902.1"
                     /translation="MKYRVETNPFSKDRYTPEQLEMFKNRQLSKNKAEAYFTRLYNQH
                     IAWVIIANVMTEYVIKFRKSATSFEEAWDALDYQRTTEIVFRAVNGLPCSEKDSGELE
                     TYLSEVSA"
     gene            complement(43240..43761)
                     /locus_tag="ACF4ZO_000323"
     CDS             complement(43240..43761)
                     /locus_tag="ACF4ZO_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rha family transcriptional regulator"
                     /protein_id="HFD5485903.1"
                     /translation="MRYLLEAFGVLSFEIHKPEKGSLGGRPRRIYHLNEQQATLLVTY
                     LGNTEPVREFKKNLVKAFFEMREELTQIRLQRSLEAPKRKTLNEAIKTWEHAPKMAYP
                     TVYNLLLKAVTGKNSKQLKVTRGGYSDIDCLNSIELAQYTALEDMAIALINLNFTYQD
                     IKTMALKNTLQCA"
     gene            complement(43910..44032)
                     /locus_tag="ACF4ZO_000324"
     CDS             complement(43910..44032)
                     /locus_tag="ACF4ZO_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5485904.1"
                     /translation="MNLVYMDGKKDPYTTHDIIAEHAEIDIISVRKLIDKHKKD"
     gene            complement(44045..44452)
                     /locus_tag="ACF4ZO_000325"
     CDS             complement(44045..44452)
                     /locus_tag="ACF4ZO_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5485905.1"
                     /translation="MARTPFTQELLHQIFDDTGTMSLELIAERLPDWSEKDIKLRLAA
                     WRYRNNIAYTMANGEIDTFEIINNRKAISEEVSAGRQLKLEEYFKQVQATAEIINKPT
                     ASDTNRLKAIQLQQVAMDEIPDQYFKELTELYG"
     gene            complement(44473..45081)
                     /locus_tag="ACF4ZO_000326"
     CDS             complement(44473..45081)
                     /locus_tag="ACF4ZO_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage repressor protein"
                     /protein_id="HFD5485906.1"
                     /translation="MRTETWNGYTIRFVEHNGEWWAVLADIAKALDLNPKFIKQRLGD
                     EVVSNNHVADSLGRQQEMLIVNEFGIYETIFSSRKKEAKTFKLWVFEIIKQLRQSTGL
                     EGFQVFRMFDKEHQKQAMNRLVNGLEQVKQTDLIKANTIANKAVSNKYGLPKMISKSQ
                     MTEQMLKDREQLLDDTVELMVIKDKFDLGISVSNAIYSRATH"
     gene            complement(45095..45292)
                     /locus_tag="ACF4ZO_000327"
     CDS             complement(45095..45292)
                     /locus_tag="ACF4ZO_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017644139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD5485907.1"
                     /translation="MKNNLRVILARQRKKISDVHEATGVSKTTLTALYYERTENPDSK
                     TLLKIAKCLNVTLDELLTVED"
     gene            45456..46136
                     /locus_tag="ACF4ZO_000328"
     CDS             45456..46136
                     /locus_tag="ACF4ZO_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD5485908.1"
                     /translation="MIKTNFAVLMAERGLKIADVYEDTGISKTTLMALSENTGKGVQF
                     DTVDKLCNYLGIELKDFFVYSPYIWKAYNKEDYEYKEEGDNLIAINLKSTHSERVYIL
                     KLFFFSPKHIDSPTDDTTVKLWVRLSLDEDSGNYGYNEFYDFISSLPISFQTHFYNDV
                     IEVLKKHYLNSGAVISAYRYDFHPDKEYLSEIVLNKNDKVIVSFFDSYGNSHAPKAIQ
                     IDKLIKVD"
     gene            complement(47008..47151)
                     /locus_tag="ACF4ZO_000329"
     CDS             complement(47008..47151)
                     /locus_tag="ACF4ZO_000329"
                     /inference="COORDINATES: protein motif:HMM:NF028245.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HFD5485909.1"
                     /translation="MSGGGAYVCKSQKPKERRRQGLSVYETLTLMIAFGTLIVAIMNN
                     KNK"
     gene            47473..48624
                     /locus_tag="ACF4ZO_000330"
     CDS             47473..48624
                     /locus_tag="ACF4ZO_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFD5485910.1"
                     /translation="MIMKITEHKKKNGTIVYRASIYLGIDQMTGKRVKTSITGRTRKE
                     VNQKAKHAQLDFLSNGSTIKRKVVIKTFKELSHLWLETYKLTVKPQTYDATVTRLNRH
                     IMPTLGNMKVDKITASDIQMLINRLSKYYVNYTAVRSVIRKVLQQGVLLGLIDYNSAR
                     DIILPRKQPNAKKKVKFIDPSDLKSFLEHLETSQHKRYNLYFDAVLYQLLLSTGLRIG
                     EACALEWGDIDLENGTIAINKTYNKNLKFLSTAKTQSGNRVISVDKKTLRSLKLYQMR
                     QRQLFNEVGARVSEVVFATPTRKYFNASVRQSALDTRCKEAGIERFTFHAFRHTHASL
                     LLNAGISYKELQYRLGHANISMTLDTYGHLSKDKEKEAVLYYEKAMNNL"
     gene            48719..50701
                     /gene="mutL"
                     /locus_tag="ACF4ZO_000331"
     CDS             48719..50701
                     /gene="mutL"
                     /locus_tag="ACF4ZO_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0032300 - mismatch repair complex
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HFD5485911.1"
                     /translation="MTNIIELPEVLANQIAAGEVVERPASVVKELVENAIDAKSSQIT
                     VEIEESGLKMIQVTDNGEGMSHEDLPLSLRRHATSKIKSQSDLFRIRTLGFRGEALPS
                     VASISKITIKTATKEVTHGSLLIATGGEIETLEAISTPTGTKIKVENLFYNTPARLKY
                     MKSLQAELAHIVDVVNRLSLAHPEVAFTLISDGRQLTQTSGTGDLRQAIAGIYGLNTT
                     KKMLAISNADLDFEVSGYVSLPELTRANRNYMTILVNGRYIKNFLLNRAILDGYGSKL
                     MVGRFPIVVIDIQIDPYLADVNVHPTKQEVRISKERELMALISTAISESLKEQDLIPD
                     ALENLAKSSTRHFSKPEQTQLPLQSRGLYYDPQKNDFFVKESAVSEKIPETDFYFGAV
                     DNSVKVEKAELLPHSEEVIGPSSVKHASRPQNTFTETDHPNLDLKNRQKLSQMLNRLE
                     NEEKSVFPELDYFGQMHGTYLFAQGKDGLFIIDQHAAQERVKYEYYRDKIGEVDSSLQ
                     QLLVPYLFEFSGSDFINLQEKMALLNEVGIFLEVYGHNTFILREHPIWMKEEEIASGV
                     YEMCDMLLLTNEVSIKTYRAELAIMMSCKRSIKANHSLDDYSARNLLLQLAQCQNPYN
                     CPHGRPVLINFSKADMEKMFRRIQENHTSLRELGKY"
     gene            50712..51932
                     /locus_tag="ACF4ZO_000332"
     CDS             50712..51932
                     /locus_tag="ACF4ZO_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MDR family MFS transporter"
                     /protein_id="HFD5485912.1"
                     /translation="MQEFLNLPKQIQLRQLVRFVTITLGSSIFPFMAMYYTTYFGTFW
                     TGLLMMITSLMGFVGTLYGGHLSDALGRKKVIMIGSVGTTLGWFLTILANLPNAAIPW
                     LTFAGILLVEIASSFYSPAYEAMLIDLTDESNRRFVYTINYWFINIAVMFGAGLSGLF
                     YDHHFLALLVALLLVNVLCFGVAYYYFDETRPETHAFDHGKGLLASFQNYRQVFHDRA
                     FVLFTLGAIFSGSIWMQMDNYVPVHLKLYFQPTAVLGFQVTSSKMLSLMVLTNTMLIV
                     LFMTVVNKLTEKWKLLPQLVVGSLLFTLGMLLAFTFTQFYAIWLSVVLLTFGEMINVP
                     ASQVLRADMMDHSQIGSYTGFVSMAQPLGAILASLLVSVSHFTGPLGVQCLFVVIALL
                     GIYFTVVSAKMKKV"
     gene            51934..52530
                     /gene="ruvA"
                     /locus_tag="ACF4ZO_000333"
     CDS             51934..52530
                     /gene="ruvA"
                     /locus_tag="ACF4ZO_000333"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009379 - Holliday junction helicase
                     complex [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HFD5485913.1"
                     /translation="MYDYIKGQLTKITAKYIVVEANGLGYMINVANPYSFTDSVNQLV
                     TIYLHQVIREDAHLLFGFHTEDEKDVFLKLISVSGIGPTTALAIVAVDDNEGLVNAID
                     NSDIKYLMKFPKIGKKTAQQMVLDLAGKFVEAPQETGHTKARSNKAGNTQLDEAIEAL
                     LALGYKATELKKIRAFFEGTSETAEQYIKSALKLLMKG"
     gene            52540..53100
                     /locus_tag="ACF4ZO_000334"
     CDS             52540..53100
                     /locus_tag="ACF4ZO_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HFD5485914.1"
                     /translation="MKRCSWVPKDNQLYCDYHDLEWGQPLDDDRDFFELLCLESYQSG
                     LSWLTVLKKRQAFRTVFHHYDIASVATFTSEEMADALENPSIIRHKLKLAATVNNAIA
                     VQKIQKEFGSFSTYLWNFVGGKPINNLVNQENLVLAQTELSIRLAKDLKKRGFKFLGP
                     TTVYSFMQASGLVNDHEEACVFNRIF"
     gene            53169..54440
                     /locus_tag="ACF4ZO_000335"
     CDS             53169..54440
                     /locus_tag="ACF4ZO_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HFD5485915.1"
                     /translation="MKAELIAVGTEILTGQIVNTNAQFLSEKMAELGIDVYFQTAVGD
                     NEERLLSVITTASQRSDLVILCGGLGPTKDDLTKQTLAKYLRKDLVYDEQACQKLDDF
                     FAKRKPSSRTPNNERQAQVIEGSIPLPNKTGLAVGGFITVDGISYVVLPGPPSELKSM
                     VNEELVPLLSKQYSTLYSKVLRFFGVGESQLVTVLSDFIENQTDPTIAPYAKTGEVTL
                     RLSTKTENQALADKKLGQLEAQLLSRKTLEGQPLADVFYGYGEDNSLARETFELLVKY
                     DKTITAAESLTAGLFQSTLASFPGASQVFNGGFVAYSMEEKAKMLGLPLEELKSHGVV
                     SAYTAEGMAEQARLLTGADIGVSLTGVAGPDMLEEQPAGTVFIGLATQTKVESIKVLI
                     SGQSRLDVRYIATLHAFNMVRKTLLKLENLL"
     gene            54529..55665
                     /gene="recA"
                     /locus_tag="ACF4ZO_000336"
     CDS             54529..55665
                     /gene="recA"
                     /locus_tag="ACF4ZO_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008094 - ATP-dependent activity, acting
                     on DNA [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HFD5485916.1"
                     /translation="MAKKLKKNEEITKKFGDERRKALDDALKNIEKDFGKGAVMRLGE
                     RAEQKVQVMSSGSLALDIALGAGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLSASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGTTQIKGTGDQKDSSIGKETKIKVVKNKVAPPFKVAE
                     VEIMYGEGISRTGELVKIASDLDIIQKAGAWFSYNGEKIGQGSENAKRYLAEHPELFD
                     EIDRKVRVKFGLLEESEEESAMAVASEETDDLALDLDNGIEIED"
     gene            55956..56354
                     /gene="spx"
                     /locus_tag="ACF4ZO_000337"
     CDS             55956..56354
                     /gene="spx"
                     /locus_tag="ACF4ZO_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HFD5485917.1"
                     /translation="MIKIYTISSCTSCKKAKTWLNAHKLAYKEQNLGKEPLTKEEILA
                     ILSKTENGVESIVSSKNRYAKALDCDIEELSVSEVIDLIQDNPRILKSPILIDDKRLQ
                     VGYKEDDIRAFLPRSIRNIENTEARLRAAL"
     gene            56467..56736
                     /locus_tag="ACF4ZO_000338"
     CDS             56467..56736
                     /locus_tag="ACF4ZO_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HFD5485918.1"
                     /translation="MGFTDETVRFKLDDGDKRQISETLTAVYHSLDEKGYNPINQIVG
                     YVLSGDPAYVPRYNDARNQIRKYERDEIVEELVRYYLQGNGIDVK"
     gene            56733..57152
                     /gene="ruvX"
                     /locus_tag="ACF4ZO_000339"
     CDS             56733..57152
                     /gene="ruvX"
                     /locus_tag="ACF4ZO_000339"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HFD5485919.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIKIDEEKAEFGFTR
                     LEELVKQYQVEQFVIGLPKNMNNTNGPRVDASITYGNHIEHLFGLPVHYQDERLTTVE
                     AERMLIEQADISRGKRKKVIDKLAAQLILQNYLNRNF"
     gene            57164..57469
                     /locus_tag="ACF4ZO_000340"
     CDS             57164..57469
                     /locus_tag="ACF4ZO_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HFD5485920.1"
                     /translation="MTHNHENDHQHEVITLVDEQGNETLFEILLTIDGREEFGKNYVL
                     LVPAGSEEDESGEIEIQAYSFTENEDGTEGDLQPIPEDSDAEWDMIEEVFNSFLDEN"
     gene            57882..59441
                     /locus_tag="ACF4ZO_000341"
     CDS             57882..59441
                     /locus_tag="ACF4ZO_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2079 domain-containing protein"
                     /protein_id="HFD5485921.1"
                     /translation="MIELNDEFIRKETIELANDGPRVHTTQYETKVPRLHKCYLLFFS
                     IIISSLTIAVPFLTDAANGLQSQNLYIGMMLTKGQVPYSDTFTTGGLFYFVIIALSYY
                     LGSTLWLVFVQVFCFYLSGLYLYKLINYMTGFQKVALTFSISYYLLSVSLGFGGLYPT
                     QLAMPFILISAWFLTKYFACLVKDEAFILFGFVGALAMLIDPSTLIFWSFACVTVFSY
                     NISQKHLARGFYQLLASIFGMILVFYTAGYFILNLQVLNPYLSQTMIYPFTFFKSGNL
                     SLLFGLAIQLFFALGLGLLTGMENVIRRFKNNSDRVVKWLFVMVILESILVAIFSQDY
                     RPYHLLPLLPFGLILTAIPVGYQYGIGLGQSSHRRRHGKNGVGRVMMIYLKRHFYLPI
                     LIVGTILICSTYCFISSIPLNQERDHIASYLEQKLNKTQSIYVWDDTSKIYLDSKAKS
                     VSQFSSPDINTQKASHRKILEDELLENKAAYIVVNRYKNLPKIIQKVLSTNYKVDKQI
                     TTKSFIVYQKK"
     gene            59538..61736
                     /gene="nrdD"
                     /locus_tag="ACF4ZO_000342"
     CDS             59538..61736
                     /gene="nrdD"
                     /locus_tag="ACF4ZO_000342"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011529096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008998 - ribonucleoside-triphosphate
                     reductase (thioredoxin) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HFD5485922.1"
                     /translation="MVSLEEDKVTVQPDIKVIKRDGRLVNFDSTKIYSALLKASMKVT
                     RMSPLVEAKLEAISDRIIAEIIERFPTNIKIYEIQNIVEHKLLAANEYAIAKEYINYR
                     TQRDFARSQATDINFSIDKLINKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLKM
                     LPSHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLANGFKIGNAEVESPKSIQT
                     ATAQISQIIANVASSQYGGCTADRIDEFLAPYAELNFKKHMADAKKWIVETKRESYAF
                     EKTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSWFEREIQKAILTIRINGL
                     GSEHRTAIFPKLIFTVKRGLNLEPDSPNYDIKTLALECATKRMYPDMLSYDKIIDLTG
                     SFKSPMGCRSFLQGWKDENGQDVTSGRMNLGVVTLNLPRIAMESNGDMDKFWELFNER
                     MLISKDALIYRVERVTEAKPANAPILYQYGAFGKRLEKTGNVNDLFKNRRATVSLGYI
                     GLYEVASVFYGGQWEGNPDAKAFTLSIVKAMKQACEDWSDEYGYHFSVYSTPSESLTD
                     RFCRLDTEKFGIVTDITDKEYYTNSFHYDVRKSPTPFEKLDFEKDYPEAGASGGFIHY
                     CEYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDKCYNCQFEGDFTPTERGFTCPNCG
                     NNDPKTVDVVKRTCGYLGNPQARPMVNGRHKEISARVKHMNGSTIKYPGL"
     gene            61918..62064
                     /locus_tag="ACF4ZO_000343"
     CDS             61918..62064
                     /locus_tag="ACF4ZO_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5485923.1"
                     /translation="MGKYQLDYKGMQQVERFHEKHSKKKTDKKSRVQELKARFLEKSK
                     KQDN"
     gene            62093..63028
                     /locus_tag="ACF4ZO_000344"
     CDS             62093..63028
                     /locus_tag="ACF4ZO_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFD5485924.1"
                     /translation="MLNIGIVGLGAISQKAYLPYMRQLSDITWHLSTRNAAVRQQVGQ
                     LFGHAILYSDVKELSKASLDGVFIHAATSAHAELASLFLNQGIPVFMDKPIADNYLMT
                     KNLYDLAKENQTFLMAGFNRRFTPRVKKLSSLSTKRKVAVEKNDLNRPGDMTFKLFDF
                     FIHPLDTALFLSEGTLLKGHFQYHLEAGLLSQVMVTLMTESMTTTASMNLQSGSRREV
                     MEVQRAEETYHLENLDELSIYKGTEKRVLGFASWDTTLHKRGFETMIDAFLEAISTGV
                     NPVSPESSLLSHWICQQIADSQLSYGELTVELPKD"
     gene            63037..63546
                     /locus_tag="ACF4ZO_000345"
     CDS             63037..63546
                     /locus_tag="ACF4ZO_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFD5485925.1"
                     /translation="METRRPTLKDKDAVLSMINEFLEQKSATDGLWHFNVNDFNYETW
                     LEDSLRQEMGLASQGVPAIQYVAFDEKNQALGFLNLRLRLNASLLEKGGHIGYSVRPS
                     QRGKGYAKEMLKQAVSCAISKNITTILVTCDETNVASRAVIVANGGVLEDSRGGTERY
                     WIEEQRGDK"
     gene            63546..64160
                     /gene="nrdG"
                     /locus_tag="ACF4ZO_000346"
     CDS             63546..64160
                     /gene="nrdG"
                     /locus_tag="ACF4ZO_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HFD5485926.1"
                     /translation="MAEKCWNNPKPKEWQAEELSQGRIIDYKAFNFVDGEGVRNSLYV
                     SGCLFHCKGCYNAATWSFKAGMPYTQELEEQIMTDLAQPYVQGLTLLGGEPFLNTGIL
                     IPLIKRIRRELPEKDIWSWTGYTWEEMMLETPDKLEMLSLIDILVDGRFDITKKNLML
                     QFRGSSNQRIIDVQKSLAAKEVIIWDKLNDGDQTFEQISREDLL"
     gene            complement(64334..65065)
                     /gene="yaaA"
                     /locus_tag="ACF4ZO_000347"
     CDS             complement(64334..65065)
                     /gene="yaaA"
                     /locus_tag="ACF4ZO_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HFD5485927.1"
                     /translation="MLTFLIPTAKEMTTPKESHPHLLPQDSQAILKIMTAMTTEDLAK
                     SYRIKEEAAKKEQQRWQDMASQQSLAYPAYQLFNGLMYRHIKRDKLTTQEQAYITQQV
                     YITSSFYGIIPANHPIAEHRHDFHTRIKIEGQSLKSYWRPCYNQFAKEHPQVISLLSS
                     EFDDVFSKDCKQLWISPKFMAEKEGQFKTHSTISKKARGAFLTACMENNCQTVDSLKS
                     LVFAGFYYHPDLSTDYEFVYIKKEA"
     gene            complement(65107..65955)
                     /locus_tag="ACF4ZO_000348"
                     /pseudo
     CDS             complement(65107..65955)
                     /locus_tag="ACF4ZO_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982226.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
     gene            66141..66467
                     /locus_tag="ACF4ZO_000349"
     CDS             66141..66467
                     /locus_tag="ACF4ZO_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HFD5485928.1"
                     /translation="MLKKRPACPVETTLSVIRNKWKLLILRDLLKGTLRFGQLKSSIG
                     SVSQKVLTAQLRAMEAHREVYAEVPPRVEYSLTETGLSLAPVIEAMSDWDQTYQEKHA
                     DLFEEG"
     gene            complement(66746..67459)
                     /gene="treR"
                     /locus_tag="ACF4ZO_000350"
     CDS             complement(66746..67459)
                     /gene="treR"
                     /locus_tag="ACF4ZO_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HFD5485929.1"
                     /translation="MTKYERIYKDLETKINKDFYKEGDFLPTEIELSQQYQASRDTVR
                     KALSLLTKAGLILKKQGRGTQVIKHHQIMFPISELTSYQELVSYSNLDSKTNVIAIDK
                     LIVDETLSKLTGFSKNSLVWRVTRQRVVEGVASVLDIDYLSKTLVPIMTREIAEHSIY
                     QYLEKELHLAIDFALKEVTIDQITDRDKILLDLGSDQHVVSVKSKVYLSNNNQFQFTE
                     SRHKLEKFKFLDFARRRPK"
     gene            67670..69694
                     /gene="treP"
                     /locus_tag="ACF4ZO_000351"
     CDS             67670..69694
                     /gene="treP"
                     /locus_tag="ACF4ZO_000351"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015574 - trehalose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015771 - trehalose transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HFD5485930.1"
                     /translation="MGKFEQDAKSLLTAIGGKENIKAVTHCATRMRFVLNDNNKANVK
                     EIEKISVVKGTFTNAGQFQVIIGNDVPVFYNDFTAVSGIEGVSKEAAKSAAKSNQNAL
                     QRVMTMLAEIFTPIIPAIIVGGLILGFRNILESVPFEFLGQQVEKGKLVFDAAGDPVW
                     NTIVRVSPFWSGVNHFLWLPGEAIFHFLPVGITWSVTRKMGTTQILGIVLGICLVSPQ
                     LLNAYAVAGTPAAEIAKNWVWDFGFFTINRIGYQAQVIPALLAGLSLAYLEIFWRKRI
                     PEVVSMIFVPFLSLIPALILAHTVLGPIGWIIGKGISFVVLAGLTGPVKWLFGAIFGA
                     LYAPLVITGLHHMTNAIDTQLIADTATRTTGLWPMIALSNIAQGSAVFAYYLMNRHEE
                     REAEISLPAAISAYLGVTEPALFGVNVKYVYPFVAGMIGSGIAGLLSTTFNVQANSIG
                     VGGLPGFMAINVKYMIPFFICMAVAIVVSMFLTFFFRKSHIMTKTEDEAKLPETPVSE
                     APAATAPHKTMQGTVITLTSPLTGEVKALSEAVDPVFAQGIMGQGALLQPTEGVLVAP
                     CDAEVSVLFPTKHAICLVTTEGLELLMHIGMDTVNLDGQGFEALVKQGDQVKAGQTLI
                     QFDIAAISEAGYATETPLVVTNQDAFTVTVEGSLPHQIKANDKLAVAVKK"
     gene            69761..71389
                     /gene="treC"
                     /locus_tag="ACF4ZO_000352"
     CDS             69761..71389
                     /gene="treC"
                     /locus_tag="ACF4ZO_000352"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008788 - alpha,alpha-phosphotrehalase
                     activity [Evidence IEA];
                     GO_process: GO:0005991 - trehalose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HFD5485931.1"
                     /translation="MTIDKKKVVYQIYPKSYKDTTGNGVGDLRGIIAKLPYLQELGID
                     MIWLNPFYPSPQRDNGYDVSDYTAVNPDFGTMADFEDLVKAAKEHQIELMLDMVLNHC
                     STDHEWFQKALAGDPYYQDFFILRDQPTDWVSKFGGNAWAPFGDTGKYYLHLFDVTQA
                     DLNWRNPHVREELAKVVNFWRDKGVKGFRFDVINLIGKDEELVDCPVNDGKPAYTDRP
                     ITHTYLHDLNQASFGQDDSFMTVGEMSATTIDNCLLYTAPEREELSMAFNFHHLKVDY
                     ENGQKWTIMAFDFAALRDLFHAWGEGMSQGNGWNALFYNNHDQPRALNRFVDVTHFRN
                     EGATMLAASIHLSRGTPYIYMGEEIGMLDPDFDSMDDYVDVESLNAYSSLLVSGKSAE
                     EAFAIIKDKSRDNARTPMQWDASEHAGFTTGKPWLEVSKSYRDINVETEKEGRIFPFY
                     QRLIALRKELPIIAEGDYRAAFKDSQSVYAFERHLGDQCLLVLNHFYADEVELELPPR
                     YQHGQVLISNYEKVSICEKVILKPYQTLAILAEN"
     gene            71597..73492
                     /gene="pepO"
                     /locus_tag="ACF4ZO_000353"
     CDS             71597..73492
                     /gene="pepO"
                     /locus_tag="ACF4ZO_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HFD5485932.1"
                     /translation="MTTYQDDFYQAVNGKWAETAVIPDDKPRTGGFSDLADEIEALML
                     DTTDAWLAGENIPDDAILKNFVKFHRLVADYAKRDEVGVSPILPLIEEYQSLKSFSEF
                     VANIAKYELAGLPNEFPFSVAPDFMNAQLNVLWAEAPSILLPDTTYYEEDNEKAEELR
                     GIWRQSQEKLLPQFGFSTEEIKDLLDKVIELDKQLAKYVLSREEGSEYAKLYHPYVWA
                     DFKKLAPELPLDSIFEKILGQVPDKVIVPEERFWTEFAATYYSEANWDLLKANLIVDA
                     ANAYNAYLTDDIRVESGAYSRALSGTPQAMDKQKAAFYLAQGPFSQALGLWYAGQKFS
                     PEAKADVESKVARMIEVYKSRLETADWLAPATREKAITKLNVITPHIGYPEKLPETYA
                     KKVIDESLSLVENAQNLAKITIAHTWSKWNKPVDRSEWHMPAHLVNAYYDPQQNQIVF
                     PAAILQEPFYSLDQSSSANYGGIGAVIAHEISHAFDTNGASFDEHGSLNDWWTQEDYA
                     AFKERTDKIVAQFDGLESHGAKVNGKLTVSENVADLGGVACALEAAQSEEDFSARDFF
                     INFATIWRMKAREEYMQMLASIDVHAPGELRTNVTLTNFDAFHETFDIKEGDAMWRAP
                     KDRVIIW"
     gene            complement(73658..74698)
                     /gene="tsf"
                     /locus_tag="ACF4ZO_000354"
     CDS             complement(73658..74698)
                     /gene="tsf"
                     /locus_tag="ACF4ZO_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor Ts"
                     /protein_id="HFD5485933.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDMDKAVELLREK
                     GMAKAAKKADRVAAEGLTGVYVHGNVAAVVEVNAETDFVAKNAQFVELVNATAKVIAE
                     GKPANNDEALALVMPSGETLAEAYVNATATIGEKISFRRFALIEKTDEQHFGAYQHNG
                     GRIGVISVVEGGDDALAKQVSMHIAAMKPTVLSYTELDAQFIKDELAQLNHAIELDNE
                     SRAMVDKPALPFLKYGSKAQLSDDVITAAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLDSVNAKAIAFARFEVGEGIEKKANDFES
                     EVAATMAAALNN"
     gene            complement(74832..75599)
                     /gene="rpsB"
                     /locus_tag="ACF4ZO_000355"
     CDS             complement(74832..75599)
                     /gene="rpsB"
                     /locus_tag="ACF4ZO_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HFD5485934.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKLADQAYEFVRDAAANDAVILFVGTKKQAAEAVADEATRAGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEEGTFDVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNADPDDIDIIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDADVAFEADTQADSIEDIVEVVEGDNA"
BASE COUNT        22885 a        13169 c        15530 g        24220 t
ORIGIN      
        1 ccattttgac cgcatcgccc cctgtcaaac cactgataga tttggttgag gttagtcctt
       61 ctgttacagc tgctttcata acttgtaaat tgcgtgacat gattttgata atatcttctc
      121 gatttcttcc agacatctcc acttccgtgg caatcatgag ttcagcaata tttccattaa
      181 attgttggtc agcttgtttg acaagttctt caatagtata aaacatagct ttcctttcta
      241 gtcaaagaag ttgacattat aaatatgagg aatttttgca atttggttgg ctgcttcttg
      301 gcactctcta gagtcgactt ctataatcat agtagctttt tcaccagcgg attcacgtgt
      361 aacattcatt gtggcgatat taatattatt ggaagatagg atatcagtta cctttgcgat
      421 cattccggga atatctttgt gtacagtaac tatagtagga gtattcatgg ataacgagac
      481 agaaaaacca tttagttctg ttacttgaat gtttcctcct ccaattgaaa caccagtaac
      541 actaagtgtt ttgtcagctt ttttgacact gattttaaca gtattgggat ggggagcatt
      601 actatctttt aagatatccc aatagatttt tatccctttt tgatgagcaa tttctagaga
      661 atttttaata tcaggattat cagtatccat acccataatt cctgcaacaa gagccttatc
      721 agtaccatgt cctctgtagg ttttagcaaa tgaattataa aggtgaaacg tcacttcatc
      781 aggaatatct ccaaagatgg aatggactac cttaccaatt ctgacggcac cagctgtgtg
      841 actacttgat ggaccaatca ttactggccc aatgatgtca aaaactgatt gaaatttttg
      901 tgtattcata ggcaactccg ttttttattt ctatgtttat tataacaaaa aaatatcaaa
      961 aaacagcaat ataattataa aaaattattt ttataataaa aaattattga gcaataaaat
     1021 gattggcatt ccacgcagta attgttataa taaggtttgc gctgatggcg cttcaaaatc
     1081 gaccttcaaa tcgacttttg aaaacgacga ccttcaatcg tacgttaact gataagaaaa
     1141 agaatcataa tattcataat atgatgatta tctttttcta tcttattatt gatgggagaa
     1201 ttttttatga cagataactc aaagatacgt gttgtcgttg gtatgagtgg tggcgttgat
     1261 tcatctgtaa cagctctact tttaaaggag caaggttatg atgttattgg tgtcttcatg
     1321 aaaaactggg acgatacaga tgaatttggt gtttgcacag ctactgaaga ttacaaagat
     1381 gtagcagccg ttgctgatca aatcggtatt ccttactatt cagtcaattt tgaaaaagaa
     1441 tattgggaca gagtatttga atatttcttg gccgaatacc gagcaggtcg tactccaaat
     1501 cccgatgtca tgtgtaataa ggaaataaaa tttaaagctt tccttgacta tgccatgact
     1561 ttaggtgcag attatgtagc aacgggacac tatgctcaag tcaagcgtga tgaaaatggt
     1621 acggttcaca tgttacgtgg agctgataat ggcaaagacc aaacctactt tttaagtcaa
     1681 ctatcacagg aacaactaca aaagacttta ttcccccttg gtcatttgca aaagtcagaa
     1741 gttagagaaa ttgctgagcg agcagggctt gcaacggcta aaaagaaaga ttcaacaggt
     1801 atttgtttta ttggtgaaaa gaatttcaaa cagtttttga gccagtactt accggcacaa
     1861 aaaggtcgca tgatgactat tgatggtcgc gatatgggag aacatgccgg tcttatgtat
     1921 tatactattg gtcagcgtgg tggtctgggc attggtggtc agcatggtgg ggataatcaa
     1981 ccttggtttg ttgtcggtaa agatttgtcg caaaatattt tatacgttgg tcaaggtttc
     2041 taccatgaag ccctaatgtc aaatagtctt gacgcctcag tcatccattt tacacgtgag
     2101 atgccagaag agttcacatt tgaatgtact gctaaatttc gctatcgtca acccgattca
     2161 caggtgacgg tgcatgttcg aggagataag gcagaagttg tttttgcaga gccacagcgc
     2221 gcgattactc ctggtcaagc tgttgttttc tatgacggaa aagaatgcct tggtggtggt
     2281 atgattgaca tggcttataa aaatgggcag ccttgtcagt acatctaatg aatcttttat
     2341 taagataaaa agaaagggac attcaacaat tcctttgaca tcatatgata ttatttataa
     2401 aaaccaatca tgcgttaatg gattaattta tgatatctgt atattttaaa tataatcaca
     2461 ttatttttaa aaatagttcg taaaagttga gtcattactt tattagttac tgtagaaatc
     2521 atacgatcat gagacttact ttctctagta ttacaacaga tattttgatg attaggtatt
     2581 tcgtaaaaca gattatttca tgattattag tacctattat ctaatactaa atgtgtaaaa
     2641 aattattgga aattcctagt tatactttta tggttttgtt atcggcgttc ttacttgtag
     2701 acttagaaac aatggtatct gtattttact actttaagaa gatatcaaaa aatcgtatga
     2761 taatactgat gacattttta tttctcgcct cgctagatta gacatagtga tacttttgta
     2821 atcattttaa aaacattgca atagattgac agagctgtaa aaacattgac attactgtaa
     2881 aggtctgtga tgaaatcaat attgacaatc actaatcatt tttttaaaat agatagtaac
     2941 aatcggaatg atggtcaaag ctcatgaaag ttgtaggttt tttgtcctgc aatcttctag
     3001 ggttttggcc ctttttatgg tttagctcta gaaatgagat ggctaaatgg ccaggacata
     3061 ttgtccgcat tgaaagctaa actaaagcgt atgattttaa atgaatagac tgaaataaag
     3121 gattttaaaa aaatgacaca tgaatttaca gaaagctatg acgtcattgt cataggtgca
     3181 ggtcatgctg gtgttgaagc cagtttggcc actagtcgta tgggttgtaa aactttattg
     3241 gcaacaatca accttgatat gcttgctttt atgccatgta atccttctat tggaggatct
     3301 gccaaaggga tagtagtacg agaaatcgat gctcttggcg gcgaaatggg taaaaatatt
     3361 gataaaacct atatccagat gaaaatgctt aatacaggta agggaccagc tgtacgcgct
     3421 ctccgagctc aagcagataa atccctgtat gcgcgtgaga tgaaacatac cgttgaaaaa
     3481 caggctaatt tgactcttcg ccaaacgatg attgatgata ttctagttga agatggacga
     3541 gttgtaggtg ttttaacagc cacaggacaa aaatttgcag ctaaggcagt tgtagtgaca
     3601 acaggaacag ctctgcgtgg cgaaattatt ttaggagaac tcaaatattc ttctgggcct
     3661 aataatagtt tggcatcagt aaccttagca gataatttaa aaaaactcgg cttagaaatt
     3721 ggcagattca aaacaggaac gcctcctcgt gtcaaagcat cttctattaa ttacgatcaa
     3781 acggaaattc agccaggtga tgataaacct aatcattttt catttatgtc aaaagatgct
     3841 gattatctca aagatcaaat tccctgctgg ttgacttata cgaatcaaac tagtcatgat
     3901 atcattaatc agaaccttta cagagcaccg atgttttctg gcattgttaa aggtgtaggc
     3961 cctcgttact gcccatctat tgaagataag attgttcgct ttgctgataa agaacgtcat
     4021 cagcttttct tagagccaga ggggcgtgat acagaagaag tgtatgttca agggttgtca
     4081 acgagtcttc cagaagatgt ccaaaaagat ttgattcatt cgatcaaagg acttgaaaag
     4141 gctgaaatga tgcgcactgg ttatgctatt gaatatgata ttgttttacc tcaccagcta
     4201 cgtgccacac ttgaaaccaa gctaatttca ggactcttta cggctgggca aactaatgga
     4261 acttctgggt atgaagaggc tgctggccaa ggacttattg ctggaatcaa tgctgctttg
     4321 aaagttcaag gtaagtcaga acttattttg aaacggagcg atgcttatat tggcgttatg
     4381 attgacgatt tggttaccaa aggaaccttg gaaccttatc gattgttgac atcgcgagct
     4441 gagtatcgtt tgattttacg tcatgacaac gctgatatgc gtttgacaga gattggtcgc
     4501 gacattgggt tggtggatga tgagcgttgg aaggccttcg aaattaagaa aaaccaattt
     4561 gataacgaat taaaacgtct gaacagtatc aaattaaaac cagtaaaagc aaccaacgat
     4621 cgtgtgcagg aacttggttt taaaccattg acggatgcta tgatagctaa agaatttatg
     4681 cgtcgcccag aaattgatta tgcgactgca gtctcttttg ttggtcctgc ggctgaagat
     4741 ttagatgcta aaatcattga acttttagaa acagaaatca agtacgaagg ctatattcgc
     4801 aaagctttag atcaggttgc taagatgaaa cgcatggaag aaaaacgtat tcctgcaaat
     4861 attgattggg atgctattga ttctattgca actgaggcgc gtcagaaatt taagaaaatt
     4921 aatcctgaaa caattggaca agctagtcgt atttcaggag tcaatcctgc ggacatcagt
     4981 atcttgatga tttatttaga aggaaacgga aaagctcatc gaaaatatta aatggaaatg
     5041 aaattgtaat ctcaaagcaa gtggaagctc tgtatttcag ggctttttta tggtataatg
     5101 tgtgcttaag aggttataag atgaaaaaat ttcgttttga aaccattcat ttgattatga
     5161 tgggattgat tttatttgga ctactggcac tttgtgtcag tattatgcaa tcaaaaatat
     5221 taatattatt agctattttt ctcgttttgc tatttgttgt tgctctttta tggtatcaaa
     5281 aagaagctta tcaattatca gacttagctc atattgagct cttaaatgaa caaacagaag
     5341 ataacctaaa aacgctactt gataatatgc ctgttggagt agttcaattt gatcaagaga
     5401 ccaacgctgt agaatggtat aatccttatg cagaattaat ttttacaact gaagagggtt
     5461 ttatacaaaa cagtttgatt cagcaaatta ttacggaaaa acgtcgtgaa gatatttctc
     5521 aaacatttga agtttctggt aataaataca cttcttatat tgatgtatca tcaggaattt
     5581 tttatttttt tgatagcttt gtgggaaaca ggcaattagc tgatgctagt atgttaagac
     5641 cggttgttgg cattatttcg gttgataatt atgatgatat cactgatgat ttatcagatg
     5701 cagatacctc aaaaattaat tcatttgtag ctaacttcat tgatgagttt atggagtcaa
     5761 aacggatttt ttaccgtcgt gttaatatgg atcgctacta tttctttaca gactttaaaa
     5821 cattaaatga tttgatggat aataaatttt ctgtcttaga agagtttcgt aaagaagctc
     5881 aagatgctca gcgcccttta acactcagca taggaatttc ttttggtgaa gaaaatcata
     5941 gccagattgg acaggtagct cttgagaatc ttaatattgc gcttgttcgt ggtggtgatc
     6001 agattgtcat tcgtgaaaat gcggatcata cgaatccaat ttatttcggg ggagggtctg
     6061 tttctacagt taaacgttca agaacacgta cccgtgctat gatgacagct atttcagatc
     6121 gaatcaagat ggtggacaat gtttttattg ttggacatag gaaacttgat atggatgcac
     6181 taggttcagc tgttggtatg caatttttcg caggtaacat tattgaaaat agttttgccg
     6241 tttacaatcc agatgagatg agtccagata ttgaaagggc tattgagcga ttgcaggctg
     6301 acggaaagac tcgtctaatc agtgtttctc aagcaatggg tttagtgact ccaagatcac
     6361 ttttagtaat ggttgaccat tctaagatat ctttaacact ttctaaagaa ttttatgaac
     6421 agtttcaaaa tgttattgta gttgatcatc acagaagaga tgatgatttt cctgataatg
     6481 ctatcttaac ttttattgaa agtggagcaa gtagtgctgc ggagctcgtc actgagttaa
     6541 ttcaatttca aaatgctaaa aaacgtttaa ataagattca agccagtgtt ttaatggcag
     6601 gtattatgct tgatactaaa aatttttcta cgcgagtgac aagtcgtacc tttgatgtcg
     6661 ctagttactt aagaagcaaa ggaagtgata gtgttgaaat tcaaaatata tccgcaacag
     6721 attttgaaga atataagcaa ataaatgaaa ttattttaca aggagaacgt cttggtgaca
     6781 gtatcattgt agctgcagga gaaaaaaatc atctttatag caatgttatt gctagtaaag
     6841 ctgcagatac gatactgtca atggctcacg ttgaggctag ctttgtatta gttgaaacag
     6901 cttctcataa gattgctatt tcagctagaa gtcgtagtaa aatcaatgtt caacgtgtga
     6961 tggaaaaatt aggtggagga ggccacttta atcttgctgc ctgtcagtta acggatatca
     7021 gtcttcccca agcgaagcac ttattattga aaactattaa tatgacactg aaagaaacag
     7081 gagaagtaga atcatgaaag ttattttttt agcagatgta aaaggaaaag gtaaaaaagg
     7141 agaaatcaaa gaggtcctaa caggctatgc tcaaaatttc cttattaaga aaaatttagc
     7201 taaggaagca actagtcaaa gcatcggtga attaaaagga aaacaaaaag ctgaagaaaa
     7261 agctcaagct gaaatattag cagaagctca agctgtcaag gctgttttgg atgaggacaa
     7321 aacacgtgtt caatttcaag aaaaagttgg cccagatgga cgtacatttg gttccatcac
     7381 agctaaaaag atttcagaag aattgcaaaa gcaatttggt gtaaaagttg ataaacgtca
     7441 tattgtttta gatcatccta tccgcgccat tggtctaatt gaagttcctg tgaaattaca
     7501 taaggaagta acagctgaga ttaaattggc tatcacagaa gcataatata aaaaacatca
     7561 caagatttgg aggttatgag gttgcctgaa gtagctgaat tacgagttca accccaagat
     7621 ttactagcgg agcaatctgt tcttgggtca atctttatct cacctgataa gctgattgca
     7681 gtgagagaat ttatcagtcc agacgatttt tataagtacg ctcataaaat tatctttcgg
     7741 gcaatgatta ctctcagcga tcgtaatgat gccattgatg caaccactat aagaacaatc
     7801 ctagatgatc aagatgatct gcaaagtatt ggtggcttat cctatattgt tgaactagtt
     7861 aatagtgtcc caactagtgc taatgcagaa tattatgcta aaattgtagc tgagaaagct
     7921 atgttgcgtg atattattgc taggttgaca gaatctgtca acctagctta tgatgaaatt
     7981 ttaaaaccag aagaggttat cgctggagtt gagagagctt taattgaact caatgaacat
     8041 agtaatcgta gtgggtttcg gaaaatttca gatgtgctaa aagttaatta cgaggcttta
     8101 gaagcacgtt ctaagcagac ttcaaatgtt acaggtttac caactggttt tagagacctt
     8161 gacaagatta caacaggttt acacccagat caattagtta ttttagctgc tcggccagca
     8221 gtggggaaga ctgcctttgt tcttaatatt gcgcaaaatg tggggactaa gcaaaaaaag
     8281 actgttgcta ttttttcttt ggaaatgggt gctgaaagtt tagtagatcg tatgcttgca
     8341 gcagaaggaa tggttgattc gcacagttta agaacagggc aactcacaga tcaggattgg
     8401 aataatgtaa caattgctca gggagctttg gcagaagcac cgatttatat tgacgatacg
     8461 cccgggatta aaattactga aatccgcgca agatcacgga aattgtctca agaagtggat
     8521 ggtggtttag gtcttatcgt aattgactac ttacagttga ttacaggaac taaacccgaa
     8581 aatcgtcagc aagaggtttc agatatttca agacagctta aaatcctagc taaagaattg
     8641 aaagtaccag ttattgccct aagtcagctt tctcgtggtg ttgaacaaag gcaagataaa
     8701 cgaccagttt tatcagatat tcgtgaatca ggatctattg agcaggatgc cgatattgta
     8761 gccttcttat accgggacga ttattaccgt aaagaaggtg atgatgctga agaagctgtt
     8821 gaagataaca caattgaagt tatcctcgag aaaaatagag ctggggcgcg tggaacagtc
     8881 aaactgatgt tccaaaaaga atacaacaaa ttctcaagta tagcccagtt tgaagaaaga
     8941 taagaaagag agacaaaaaa tgagcgatgc atttacagat gttgcaaaaa tgaaaaaaat
     9001 taaagaggac ataagagccc atgaaggaca gttagtagaa ttaacccttg agaatggacg
     9061 gaaacgggaa aaaaataaaa ttggtaggct tattgaagtt tacagttcac tctttatcat
     9121 tgagtatagt gatagctctg atactccagg agcaattgat aattcttatg tcgaatcata
     9181 cacctattca gatattttga cagaaaaaac attaattcgt tatttagatt gatttttgcc
     9241 tcatagaggc tttttcttta caataaattg atataattat tagcgataga agattattct
     9301 gcctctattc tttttatttt gaaaaaattc ctataaaaga taatattttt aggttagatt
     9361 gaggtaaaaa agaggtcttc accatggtta agcaaatgat cttagtacta aggttaaaag
     9421 attatcgtga aataaagttt tgacacaagt gtaatcaata gaggagcttg aagtatccgg
     9481 taaaactatc ttgaagtgaa aaaacgagta aacctcccct gataaataca atatactagc
     9541 catttcagag ccattaagag tttccagtga agtgcttttg atagagagct aagaaaaaaa
     9601 cagtcaaggt ttaagaactg caaattagca tttaaattat tttttgttaa tgacagttgt
     9661 ctttattacc ataactataa cttcttataa tatagtcttc ttaattcatc agtggtggtt
     9721 cgtctcatat ctgaccttaa aatattaaac tgatcatcag atgatagata gactgacttt
     9781 acaaaacaac tttcttatgg taaactgttc tttgtgcgaa ataacagcag aaaaatatga
     9841 agctcgtcaa caggtggtta tctattcaag taacctttgc tgtttaggcg aaaaccccct
     9901 gcacgaatca ggatttttta aaccgttatt tcctcaaaaa atttagagga ggacatgtaa
     9961 tatgtcacgt tatactggtc catcatggaa acaatcacgt cgccttggtt tatcacttac
    10021 aggcacaggt aaagaattgg cacgtcgtaa ctacgttcct ggtcaacacg gtccaaacaa
    10081 ccgtagcaaa ctctcagaat atggtttgca gttagctgag aaacaaaaac ttcgtttctc
    10141 atacggttta ggtgaaaaac aattccgtaa cttgttcgtt caagctacaa aaatcaaaga
    10201 aggaactctt ggtttcaact ttatggttct tttagaacgt cgtcttgaca acgttgttta
    10261 ccgtctaggt ttagcaacta ctcgtcgtca agcacgtcaa ttcgttaacc acggtcacat
    10321 ccttgttgac ggtaaacgcg ttgatatccc ttcataccgc gttgatccag gtcaagtgat
    10381 ttcagttcgc gaaaaatcaa tgaaagtacc tgcaatcctt gaagctgttg aagctactct
    10441 tggacgtcca gctttcgtat catttgatgc tgaaaaactt gaaggttcat tgactcgcct
    10501 tccagaacgc gatgaaatta acccagaaat caatgaagca cttgtcgttg aattctataa
    10561 caaaatgctt taattttaag attaaactta caaaaagcct atttaatagg ctttttttgt
    10621 atctcataac aaatttatcc tgatcccttc attttactat ggcttctaaa aaagttatca
    10681 ctaaggctga tgacttgtaa aatgatactt tcgtaagggt tattatttag gtactcgtaa
    10741 gcattttgag aacgaattgt gtcatttctt gaggtgattc ttttttacct ttagcaatcc
    10801 aactttgaca gacaccaaaa aaagcatggg ctaagtagat actttggtat tctttttccg
    10861 tttgagataa ctcttcggta ctgaacttgt cctgtaaatc agtagtgatg agtaggcgaa
    10921 ctttattgat gataaaggcc tgtatttctt tagtaccgtt agcagacaaa agggaagaga
    10981 gaagctgttc tctttggaga aattcaaata cttcaaggaa ggcttgttct ttattttgat
    11041 attttttctc aaaaatatat tctaatttgt gaaaaaaggt ttgctgataa tagtcaatca
    11101 tttcatattt atctttatag tgtgtgtaaa aactagagcg actaattcca gctcttttag
    11161 ataatttaac tgtggtaata tcgtcaaaac tttcggtttt tagtaacata accattgctt
    11221 ttaaaattgc ttgcttcgta ttttctttac ggttgaccat ctaccatctc tccttttgaa
    11281 cacttttaga cataatgtcc aaaagtgaat ttttttctct tgtaaattta aatttaaatt
    11341 gtataatata ttttatcata atttttgaac agtatgtcca ttttaggaga aaatatgtta
    11401 gaagaattga aaacacttat taaaaatcca aaattaatga ttacaatgat tggtgtggcc
    11461 ctagtgcctg ccttatataa tttatccttt ctaggctcaa tgtgggatcc ttatggtcgg
    11521 gtcaatgacc ttcccattgc tgttgttaat catgataagc ctgcaaagag agctgataag
    11581 tcattgacaa ttgggaatga tatggtggac aagatgtcta aaagtaaaga tttagagtat
    11641 cattttgtct cagctaagca agctcaagag ggacttaaag aaggtgatta ttatatggtt
    11701 attactttac ccgaagatct ttctcaacgg gcagcaacct tattaaatcc cgaaccccaa
    11761 aaattaacta tccgttacca aacgagtaaa ggacatggaa tggtcgctgc taagatgggg
    11821 gaaacagcga tggctaagct gaaagagtct gtttcgcaaa acattacgaa gacttatacc
    11881 tcagcagttt ttagcagtat gacagacctc caatcaggat taaaagaagc ctcagctgga
    11941 agtcaggcac ttgcttcagg agcgaagacc gctcaggcgg ggagtcaaac actttcgacg
    12001 aacttagcag ccttaacggg tgctagccaa cagtttcaac aaggtactgg tcgattgaca
    12061 tcaggtttga ctacctatac agatggtgtc aaccaagtca agaatgggtt aggaacatta
    12121 tcaacggaca tccccaatta tctgaatggg gtttctaggt tatcccaggg agcttctcag
    12181 cttaatcagg gtctttcaca gttgacacaa gcaacaacac tttctgacga gaaagctaag
    12241 ggaattcaat ccttaattgt aggactacca gtcctaaatc aaggcattca gcaactaaat
    12301 acagagctat caacattgca accccctaac cttaatgctg atgagttagg taatagctta
    12361 ggagctatcg ctcaagctgc caaacaagtc attgctgaag agactgccgc tcagaatgaa
    12421 gaattatcgg ctctccaagc tactagcgtt taccaatcat taactgctga acaacaagga
    12481 gagttagctg cggccctcag tcaatctgat aaaagtcaga ccgtatctgc agcccaaact
    12541 attttaagtt ctgttcaaac tttgtcaaca agtttacagt ctctctctca agaagatcag
    12601 tcaaaacagt tggagcaact taaggaagct gttgcacaga ttgctaatca atccaatcaa
    12661 gctttgccgg gagcaagttc tgctttaact gaattatcaa cgggattagc aaaggtaaat
    12721 ggtagcttaa atcaacaagt tctaccagga agtaatcaat tgacaacagg attagcacaa
    12781 ttaaacaggt ataatactgc cattggttct ggggtaataa aactctcaga aggtgccaat
    12841 gccttgtcat ccaagtccgg agaattacta gatggtagcc atcaattatc agaaggtgct
    12901 actaaactag ctgatggtag ttctcaattg agtcagggtg gtcatcaatt aacgagcgga
    12961 ttgactgaat tatcaacagg attgtcaacc ttaaatggtt ccttagccaa agcctctcag
    13021 cagttatcgc ttgtttctgt gactgataaa aatgctaaag ctgtcgcaaa acctcttgtg
    13081 ttgaatgaga aagacaaaga tggtgttaag acgaatggga tcgggatggc accttatatg
    13141 attgctgttt ctctaatggt tgtggccctt tcaaccaacg tcatttttgc taattcttta
    13201 tctggtcgtc cggtcaaaga taaatgggat tgggctaaac aaaaatttgt tattaatggt
    13261 tttatttcga ctatgggatc cattgttctc tacttagcta ttcaattatt agggtttgaa
    13321 gcccgttatg gtatggaaac cttaggattt attatgctaa gtggttggac gtttatggct
    13381 cttgtcacag ctttggtcgg ttgggatgat cgatatggct cttttgcttc tttggtcatg
    13441 ttattgcttc aggttggctc ttcaggtggc tcttacccca ttgagttaag tggagcattc
    13501 ttccaaaagt tacatccttt cttaccaatg acttatgtgg tatctggttt acgacaaacc
    13561 atttcattat caggtcatat tggagtagaa gtgaaagtct taactggttt cttactggca
    13621 tttatggtat tagcactact catttatcgt cctaagaaaa cagtctaaat aaaataacct
    13681 caaaaaaaac agcatctaag gcagttacac tagatgctgt tttttgtctt attttgacaa
    13741 taacttgaca atttctgtca agttttttat tgtcttgtta agatcatttg atagtaatgt
    13801 ctcccttatt gagattaacc gttaaatttc cagtagctgc tttattctca gccacataag
    13861 aaataacatc tgaagttgat tccttaccaa tcttagctgg tgtcagctgt gatccaagtg
    13921 agattttacc atcttcggtt tttgtcttat aggcggtcgt ctttggattg gtcaaagtta
    13981 tgtcaacagc aacatcacca ccactaatcg tattagtgcc tttaagggta agagaatgag
    14041 cagtgaatat agcaccatta tcattggttt cctcgttttc ttgctcacta gtaacagtga
    14101 aagtcacatt ttcaaggctt gtttcttcgg cttcaacccc accaggagat agagattgga
    14161 tggtgacaga tttaagatta gtattttttg tggttaattg tccatgccct aagctaatcg
    14221 tcccattttc cacactagaa tcagtcaggt ttgaaaaaga atagtcagct tttaactcga
    14281 gatttgttaa ctgactttta gtggcttcca acataccagt gatagtagct ttcttgactt
    14341 tggtatataa aagagtaaga ttgccatcga attgcatatc ttggacagtt agatttgaca
    14401 aagtggtatg tgggacatta cttgccttaa cttcattgag gctagttttt tcaggaacag
    14461 taatggtaat agaacggtag ttcttctctt gacgactatt attgagagta aaacctaaaa
    14521 tttcaattcc accagtgatg acaacgtctt taggtttttg cgaaagagat agggtcttac
    14581 ctgttactgt tgtgacgata ggatcaataa gtttaggatg tgtgtaatag gtcactgttg
    14641 gtctttgaac gggtcctgtc tctactgtaa tagttgaggc agaactgtca atatcaagag
    14701 cagttatttg gtcaaatgtt ttgatgacct ttttgggagt tgtttggtgt ttaatgtcct
    14761 gaagtcctcc agttgcatag ccagccccta gaagaatgcc tcctagaata atacatacca
    14821 cactggtcat aaagcatttg cgtgagatat ttttcatgct tgagctcctt tcttattact
    14881 gatccactta ataaaggcaa caaaagcccg tcctgaaaaa cgaaggattg ctgtggcaat
    14941 aatccaaata agaagaccac caccaaaaca caacaaggcg ctgccgattc ccatagcttg
    15001 tgcaggaata gatgagccaa tcaaggtcaa gctttcaaac agggtcactc ctgcgacaag
    15061 aatacctgca agcccaaaaa tgtaggcggc aaagatagct gtgagcccga gcattaggga
    15121 ggcaataata aagagaatca acgccagcaa tacgggtaaa gcaatcggag cagcaaagag
    15181 ggacaaaatg gttaatccaa tgattgttgc ccgatttttg ggagttttct cgggagttgc
    15241 caagtgtttt cctagaacat ttgaaatgat ttcactggca gcttccttag gatttcctaa
    15301 atcgtcgata acctggcttt ctttgtcagg accagcttca tcaaaatatt caatataata
    15361 ttccatcgct tcatggtagt cttctctagg tagtttgcgc aagtatttat ctagttctgc
    15421 tagatactca gtccttgtca tgtcttaagc tcccttcaat aatcccgtct aaggcaaatt
    15481 tatagctctg ccattctttt tttagaaaaa tcagctgtgc tctccccgaa gaagtgacag
    15541 cataatattt acgctttcgt ccctgatgtt cttgactata agttgtcaaa aaacctgcct
    15601 tctccaattt tttaagaata ggatagaggg tggattcttt gatattagcc actagtttaa
    15661 tggtttgact aatatcgtaa ccgtaagaat catttttttc gacaatagct aaaatcagaa
    15721 attcaatcaa ggtagccgat actggaaaat acattttagg ctccttccat atataaaaat
    15781 tttatatata attattttac atatttagta taagcttagt tttttgatat gtcaatattt
    15841 tatatataaa aaaataatat atatatcaaa aatcactaac taggagtaat aagttgacca
    15901 aaaagctagg attggttatg atgaagataa gattaacaga aagagaaatt agggaaggct
    15961 atgaaggact tattaaaaca gtatcaggca aaaccactag gagaggagaa gcggtacgcc
    16021 gtatttttac ctcttattct tgtcaatgat gactggcatg tcttatatga agtcagaagt
    16081 cagcatattt cacaaccggg ggaagtttct ttcccagggg gacaagtaga aaatcaggag
    16141 acacttcaag aagctgctat ccgagaaaca gttgaggaat tgactgttga tgcgtcccag
    16201 atccagctat ggggtgaaat tgattattta gtacagtctt ctagaactat tcattgtttc
    16261 gttggtcaat tagtcgttga tgactggaag agtatagagg ctaatgaaga ggttgacagg
    16321 ttgtttacgg tccctttaca acaattactt gctaccgagc cagtttttta tcatcttgaa
    16381 gctagtcctc tcaaaacttc agattttcct tttgatcgta ttcgtcatgg gaaagattac
    16441 caatttagcc agcagtaccg tagtattccg ttttatgaaa atctagaaga aaccatatgg
    16501 ggaatgactg cccagtttac taagtgttta accgatattc taaatgatga atcaattgca
    16561 aagaaaaacc ccttagatat tgaaaaatct aaggggagat agagcactag tttgttggcg
    16621 tcaacttttt gtcaacaacc tgtaaaggtt atttgtattt ttcttctaat tgactcatcc
    16681 aaagtccgag ccaaatacca agagcaaata acacaacggc cataagccag gttaagatac
    16741 ctgcatgact gtaggaaatg gattcgggac tactactatt tggaataaga attaatagcg
    16801 tgctggataa tacaatacca atgataaagt ggtaaacttt tgaatgatgg tgctgtaaag
    16861 cataatccat acttttagaa aaagccaaga tggctaggac tcctccgata gcaataggta
    16921 agaaagtccc taataaatcc aaagatttga atcctattaa cataggacca tagagtccta
    16981 agataagtaa gagatttgac gggcttactc cagggaccag tactcctaaa gcaattaagg
    17041 cacctgctaa aataaaggtt aaaaagttag ctggtaaggt accgattaag tcatttaaga
    17101 agtaaagacc tagtcctgaa ataacaaagg taaagactag ccatagccag tcagctttgt
    17161 ctctgtgaga ctgcttggtt gactccttaa tcagactagg aatagtgccg acaatagcgc
    17221 cagcaaagcc ccataagacg ctaacttgat agtgcttaag caaaaactca acggggaaag
    17281 aaaagagagc aatacctaaa ataccaccaa ttcctactgg taagaaaaat aagacatttt
    17341 caataaagct atccctcata tgagctaaaa aggaaatcat tcgctcatag attcctaaaa
    17401 tggctgcgag aacaccaccg gatacaccag gtaaaataaa acctagtgca ataatcatgc
    17461 ctttaaaaac tcttgaaata aatgaaacca ttgttgcctc ctgaaaagaa tgattttatt
    17521 gtatcataaa tttaaagaat tgctgacaca aagctgcata tccctactaa aataattgtt
    17581 cctaataaat aatacattca attttgaaga tattttcctt aaacaccatg tctttgtgat
    17641 caagtcaagt ttgattgtca aagttgtaaa taaaatttac aaagactgta aaccttacga
    17701 taattatcaa aaagataaac gaaaaaaagc ttaggtcaaa gacttttgat agtaaactta
    17761 ttgaagaagg attatagtag ctattaaaaa ggagatttat tatgggcttt aaaaaccagt
    17821 taccttatta ttgaaaaaaa ttacagatgt cacaagaaga gcttgctgaa atgatgtatg
    17881 tttcaagaag actatctcaa actgggaaaa cggtaaaagc tatccagacc tgcaaaatct
    17941 tttgatgtta agtaagtcct tacaggttcc tttagagcaa ctaatagcag aagatatccc
    18001 aaaaatgact ttaattatta aggatgagga gattaaacaa tgtgatagga atacgcatat
    18061 tatgttattt gggacactcc taattgctat cagtatttat cctataatgt cttggttagg
    18121 ttggtgggga tatggtccgg ttgctatctt atggttgata atcatgcgta gcgccttaag
    18181 aattgagcga tttaaaaaga catatgatgt tcagacttac cgataacttg aagctatagc
    18241 aaagggtgag agcttagatc agattgataa gattaaagaa aaagcaaaat atccttatca
    18301 aaaagcatgg attgttattg cgtacacagg attgacagtg ttaataaccc tactctctat
    18361 tttgtttttt catttgtttt tttaaacacg aaaaaagcct ttgaaacgtt catttcatag
    18421 gcttttctca tctcaattat tttacttctg taaaggttaa gtattttcta ttttagctgt
    18481 tataaacctt attgtatcaa tatttattga tagttgctta ataaaaggta gagtgaatgg
    18541 tagagtagtt attgcgttag ttcagcaatc ttttcaagat aaataaatac ccacagcttc
    18601 taactttcgt tgtcgtagta accccaatag gtcatgatag ataagaatat aaaaaagggg
    18661 ctgtctggct tttgcttaac gcaagccaca gccccaagga attaacgctt ttgaccaata
    18721 aaccacaatt ggttacgaac tcgaacagga gaagagaaat aatagtctgt gtgttggatg
    18781 acaatctctt ctttcagttg tactcccgta tcctttagga ttttttgccc ctgttggtct
    18841 ctaggaactt ttagaaatac agtaatggca tcttttcgta tatctacgat acacttacgt
    18901 acagctcggt taaacccgtt atggattgga ttgatagtgg taacggtctg gtgttcaaag
    18961 ttgcttacct cctgtactcg ttcacgctgg aaaaggaagt gtcttaatag aaaggtgcga
    19021 taaatagatt ggcagtagtt cccaaggcta tctgtattca agcgttgtat catctttaat
    19081 ccagataata aggctagaag taaagaaata agagcgaatc cataacatac agaactaatg
    19141 gtatcagtaa cgtttttaac cgtatccaga ttgacaaatg tgacggtaga taattgaact
    19201 gaaacaagat tgaacagcca accgaacaca tagcagattg gagcaataag cagtaagtat
    19261 aatatgagat tgaagcttct catgaagtag gttttagtgg tcataggata cctcgcttag
    19321 tatagtaggt tggacagagt aagggtagac ttgataggag tgttcattat cgacaacttg
    19381 aatgatacct gttccgtgtc ctgttggaat gacaatcccc tctggatcta ggtctggaaa
    19441 taagaattga gtggttttct gattgatatt tccaatttgc aataatacgt ttagctgttc
    19501 cctcactgaa atgggaatag tgttatggtc aaaacgctgg cttcccaaga atagatggat
    19561 tttagcagca tgtcccaaca aggcaatttg tgatagtagg gagaaaaaag cttctttgat
    19621 attcttattg actccctctg atagagcgag gacttcatca ataacaatag ttagatgggt
    19681 aaattgatga ttgggattat catacaagat agcttgtcgt ttctgaatga gagttgcaca
    19741 ctggtttaat tgttcattga cttgtgaaac gaaatcagat tttgaatggt tttctactgg
    19801 gtggataacg gcaattttat tttctcttgc ccattggcta ggggtatcga attttgagtc
    19861 aatgataatt aggccggaca taggtttcag gacactcaag aagtaagtga gagcgtacgg
    19921 tttcccagaa cctgaatttc cagcaatagc ccagtgactc cccttatcta aattgagttc
    19981 gaagtgcttt atgacaggaa ttttcccctg ttgtaagcta gatgaaaatt tatctaaatc
    20041 aggaatcgcc aagcgttctg aaatcccctt tctccaaggg aagaataatc cacgttgaat
    20101 gtgtaagtca tccgtctcta aagggacaaa atctgtgcaa attttgattt atctattttt
    20161 tgacttccgt ttgacttaat cgataaagtt gaccttgctt ttttggaaat aactaacggg
    20221 acggacgtaa ggtaagattt tgggatattt tctttataca ttcgttctag aatatcatca
    20281 accaggaatc cgatattaaa tagtggattt tctttgagtt tttttattag gttagggata
    20341 atttctgtcg aaacattatc ataccaccat ttattgatga ggggatcaat gttttcttgc
    20401 ctaaatgttg agggtatgcc atttccgtct aattcaaata ggataccaca gacattaact
    20461 tcaaatgatt taattaaatt atcccctaac atcaaccaaa taatatcaaa catttcttca
    20521 aaattaaaga cagtcaattc attgatggta ctggttctaa aacttctagc gaggttataa
    20581 cttttttcac caacagtaat gtcaatgtca tctttcttgt gaaaagtatc catttcagtt
    20641 tcatcagaag ccaaaaaatt ttttctttga atattgaaat ttgcgaatgt cttggaaagt
    20701 ctaagacagc tggattgtat tgaaattaag tcatcgtccg aaaaagaata cattctttta
    20761 tctacagttt ccaaatctct aaataaaata gagctgaagt agtggtaaaa catattttca
    20821 acaaacttgg caatatctcc aaaaataatt tctttatagt ccgagtcggt ttgagtattc
    20881 aaataaagca atattgaagc ggtaacttgt cgctttccct tttcaacttg gctaacttga
    20941 cctgcattac ctaggtcact ttactttaaa ttatactttt ttcttaaaca tttgatacga
    21001 ttaggtattt cttgtgagta attttcatca aaaaatttca tagataagcc ccctataaac
    21061 atggaaaagt agtaaaaata gttgttatcc tagttgatta aaaaaatctc tgatttcctc
    21121 atcttttata aaataatata taattttccc ctctcttcta gtgtccaaga tgttttgatt
    21181 ggctagttta cgaagatggt gggaggcaga tgccatactg agatttagta aacaggctat
    21241 atcgcagaca cagagttctt caacagcaag gagataaaag atgatattta tctgtttatt
    21301 atcggtaaac tttgataaaa tgcgaagtga tttttggact ttttcctttt caaggtagtt
    21361 cgttgcggtt gtaacatttt gttgatttat aacattcact tggcagatat tatctttttt
    21421 caaaatattt tctcctagcc taacacagtc catagcatgt caaaactgtt gttttcaatc
    21481 aggatatata tccccaatcc taaataaaca acggcaataa accatctgct atatttttcc
    21541 aaagtttctc caacagaagg gacttgtgcc aatttttggg cagaaaaaac caagagataa
    21601 atcatgacta gaaaggtcag taaagtcact atcaaattcg ctaaatttaa ggtagtaaaa
    21661 tatgggacaa agacaccaat attgtcagca ccacaacttg caaaagtaat catagcgact
    21721 agaaaaatca ggtttttatt atctttgctc aaaccttctt tggcaatagc ttctccatca
    21781 gaatctccta aaagcaaaac tttgaggcct aggaaaattg gaatcaaacc gagcaaacct
    21841 aaaatctctt tactaggaat ataatctaag acaaatgcaa aaagcaaact tagcaatatt
    21901 agactaacag agcctagaaa ttgtcctaaa tagatgttaa tgatgtcttt tctgcttttt
    21961 cttttggcaa aaaataacat taggataata agtaagtcta cggctgtccc agaatacagg
    22021 attattgaag taacaacatt ttgaatcata aaacacctca ttcaaatata tttttgaatg
    22081 aattttaaca ttaaactttg tagatgtcaa tttcagctcc accaaaatat agataaggag
    22141 ttagtgtacc aaatattaaa aagccctgcc atcgaaatga taacagggct taacttcaat
    22201 atccaaatga tagattcatc taaaaaaggt agagtaaaag gtagagttct tattgattta
    22261 tattgcaatg taatgaactt caaaaattca aaaatcgctt aaaatcaacg ttttgacgtc
    22321 taatgacgtg tagtgaaccc cttacttaac ctctgtaaat gtaacgtgtt tacgtaattt
    22381 tggtgagtat tttttcaatt gaagacggtc tggagtgtta cgtttgtttt ttgaagtaag
    22441 gtacaagcgt tcaccagatt ctttatgttc aagtgtaata tttacgcgca tggtatctcc
    22501 cttctattat ttagcttcgt tagctttagc gattttacgt cctttgtagt atcctttaag
    22561 ggatacacgg tgagaacgtg agtaatctcc agtagtttcg tcgaattgta cagatggagc
    22621 tgtcaattta tagtgtgtac gacgtttgtt tttcttcgct tttgacgtgt gacgtgcagg
    22681 tactgccatt ttcttgttct tcctttcgat gtgtaagttt tgattttcat caacttcact
    22741 atgataacat atcttttttg taaagtaaag ttacttgaca aaacttttta tttttacaat
    22801 ttcatggtga aaatactatc aaactaaagc aaatgatata tgcttgttta aaatataaga
    22861 aaaaatggta gaatgtttaa agagaaaact aatcaaagag gtaaacttat gaaacttcaa
    22921 aaaccaaaag gaacccagga tattctgcct ggggatgctg cgaaatggca gtatgtggaa
    22981 tctgttgcgc gtgatacgtt tagccaatac aattatggag aaattcgtac tcctatgttt
    23041 gaacactacg aggtaatctc gcggtctgtg ggtgatacga ctgatattgt gacgaaggaa
    23101 atgtatgatt tctatgataa aggagatcgt cacattacct tgcgaccaga gggtacagct
    23161 ccagtggtgc gttcttatgt tgaaaataaa ttgtttgcgc cagaggtcca aaaacccgtc
    23221 aaactttatt atatcggttc catgttccgc tacgaacgtc ctcaagctgg tcgtttacgt
    23281 gaatttcacc agattggggt agaatgtttc ggcgctgcta atccagcaac agatgttgaa
    23341 accattgcga tggcctatca cctctttgaa aaattgggca ttaaggatgt cacccttcat
    23401 ttaaatagtt tggggagtcc tgagagtcgt gcagcttatc gtcaagcctt gattgactac
    23461 ttaacaccaa tgcgtgatca attatctaaa gatagtcaac gtcgcttgga tgaaaaccca
    23521 ctgcgcgtgc ttgattctaa agaaaaagaa gataaactag ccgttgaaaa agcgccttct
    23581 attttggatt acttagatga ggaaagtcag gcgcactttg aggcggtcaa agatatgctt
    23641 gaagcacttg acattcctta tgtgattgac accaatatgg tgcgtggcct tgattactat
    23701 aaccacacta tttttgaatt catcacgtct gtggaaggtt ctgacttaac tatctgtgcg
    23761 ggtggacgtt atgatagttt ggtaggttat tttggcgggc ctgagactcc aggatttgga
    23821 tttggtcttg gtttagaacg tctcttgatg gttattgaaa agcagggcat taccttgcca
    23881 attgagacag agatggatgt ttaccttgct gtgttaggtg atggtgctaa tagcaaagct
    23941 ttagaattgg ttcaagccat tcgtcgtcaa gggtttacag ctgaacgaga ttaccttggc
    24001 cgtaagatta aggctcagtt taaatcagcc gataccttta aagcaaaatt ggtaatgact
    24061 ttaggagaaa gtgaagttga agcaggcaaa gctgtgatta agaataatcg tagtcgtcaa
    24121 gaagtggaag tcagttttga agatatgatg acaaactttg cgaacatctc agagcaatta
    24181 ttatcttaat gattttattg tcgtcataag cttgtgttga tatgattgtt tagaagataa
    24241 tcactaaaac aggtgtaact tctcttttta gaagggagtt gcacctgttt gttttctgta
    24301 aggggattga ttagctttct tagtattctg tgaggacacc tgatatgtca aaatactgac
    24361 ggctcagtat tcttgcttta tctttagaaa aactcttttt aaatgggtgg ggtttttaag
    24421 ggctttttgc tataatagta gggaatgaat taattgattt atatagtgaa aggaattgga
    24481 aacgagcagg tttcacagga ttctgtttgt tttagggaat ttatttatga aacgtagcat
    24541 gtatgcaggg cgtgttcgcg aagaacacat tggaacgaca atcacattga aaggatgggt
    24601 cagtcgtcgt cgtgacttgg ggggtctcat ctttattgat ttgcgtgacc gtgagggtgt
    24661 gatgcaatta gtcattaacc ctgaggaagt ttccagtgat gtgatggcaa ctgctgaacg
    24721 cttacgtagt gaatatgtga ttgaagtgga aggttttgtt gaagctcgac aacaagccaa
    24781 tgataagttg gcgacaggaa tggttgagtt aaaagtatct gctttgacca ttttaaacac
    24841 agctaaaacg acgccttttg aaattaaaga tgacgttgaa gtaagtgacg acacgcgttt
    24901 acgttaccgt tacttagatt tacgacgtcc agaaatgtta gaaaacttca agctacgtgc
    24961 aaaagtgact cattctatcc gtaattacct tgatgacctt gagtttatcg atgtcgagac
    25021 acctatgttg acaaaatcaa ctccagaagg tgcgcgtgac tatctggtac caagtcgtgt
    25081 tagccaaggg catttctatg ctttgccaca aagtccgcaa attaccaaac agttattgat
    25141 gaatgctggc tttgatcgct attatcaaat tgtgaaatgt ttccgcgatg aagatctacg
    25201 tggtgaccgt caacctgagt ttacacaagt tgacttggaa acgtcattcc tttctgaaca
    25261 agagattcaa gacatcgttg aaggcatgat tgctaaagtg atgaaagaga caaaagaaat
    25321 agatgtaacc ctaccattcc cacgtatgag ctacgatgta gcaatgaata gctacggctc
    25381 tgataaacca gacacacgtt ttgagatgct tttacaagac ttgacagtaa ctgtcaaggg
    25441 aattgacttc aaggttttct cagaagcacc agctgtcaag gcgattgtgg tgaagggaaa
    25501 tgcagatcga tactctcgta aagatattga caaattaact gagtttgcca aacaatttgg
    25561 tgctaaaggc cttgcctggg ttaaggtgac agatggtcaa ttggcaggcc cagtagccaa
    25621 gttcttgaca gctattgaga cagagttgtc aagccaatta aaacttgctg agaatgattt
    25681 ggttttattt gtagcggata ctcttgaggt tgctaataat acattaggtg cccttcgtaa
    25741 tcgtattgcc agggaccttg acatgattga tcagtcgcag tttaatttcc tttgggtggt
    25801 tgattggcca atgtttgagt ggtcagaaga agaaggacgt tatatgtcag ctcatcaccc
    25861 attcactctt ccaacgccag aatctgctca tgagttagag ggtgatttgg ctaaggtacg
    25921 ggctattgct tatgacatcg ttttaaatgg ttacgagctt ggtggtggta gcctgcgtat
    25981 caatcaaaaa gagatgcaag agcgcatgtt caaggctctt ggctttaccg ctgatgaagc
    26041 taacgaccaa tttggtttct tactagaagc gatggactac ggctttcctc ctcatggtgg
    26101 cttggcaatt ggtcttgacc gctttgtcat gttgcttgct gaggaagaca acatccgtga
    26161 agtaattgcc ttccctaaaa ataacaaagc ctctgatcca atgacgcaag cacctagtct
    26221 tgtttctgaa aaccaattag aagaactcag ccttcaaata gaaagtcatg attaagaaaa
    26281 caacctataa gaaaaaagtt aaatatgtca ttagtagagg ggccaagaaa gttggcctac
    26341 tccacgctct aagaagtatt tcaagagaaa aatatgcaga gaagatttcg gcttctctgc
    26401 tttatggcat tctctctagt attgctgtga attttttctt ccagcctggg catgtttatt
    26461 caagtggagc aactggtcta gcacaggttt tttcagctct tagtcatcgt cttttaggct
    26521 gtgattttcc catcgccttt gcgttttatt tgattaatat tcctttgctt attttagctt
    26581 ggtataaaat tgggcatcaa tttaccattt ttacctttat cacagtcagc atgagttctt
    26641 tctttattca aatcatgcct caagtgacgc tgacgactga tcctcttatc aatgctattt
    26701 ttggtggttt ggttatggga atgggaattg gtacaggtct caaatcacgt atctctagtg
    26761 gggggactga tattgtcagt ttgaccctta gaaaacgaac gggcaaggat gtgggcagtc
    26821 tctcattgat ggttaatggt gcaattttag cctttgcagg gattttattt ggctggcagt
    26881 acgcccttta ttctatggtc tctatctttg tatcaagtcg tgttacggat gccattttta
    26941 ccaagcaaaa gaaaatgcag gcaaccatta ttaccagcca tccagagcgt gtgattcata
    27001 tgatccataa acgtctgcat cgcggggtga ccagtatcaa cgacgcagaa gggacttaca
    27061 agcatgaaca aaaagcagtt ttgatcacca ttttgacatg tgaagaatac ccagaattca
    27121 aatggctgat gttaaaaaca gatccacaag cctttgtttc agtggctgag aatgttagaa
    27181 ttatcggtcg ttttgtggaa gatgattaag aaaaacacag gaggtgtcat gtcaattgac
    27241 caacgtttac agttaaagaa attttgcttt attattttag gagctgctat ctacgccttt
    27301 gcttttgttt atttttacat ggctaatcgc attgcagcca atggtttagc tggtctcacc
    27361 ctagttggta aggcactttt tgagattgat ccttctttga taggatattt gattaatttg
    27421 cctttggtct tgttgggagc tagatgtttt gggaaaagag ccatggttta cacagtaatg
    27481 ggtattttgt cactttactt ttttgtgtgg ctctttcaac gctttccttt ggtcgttgac
    27541 ttggaccatg acaatttagt cgtttccttg atggctggaa ttattggtgg tctaggtggc
    27601 ggtcttgtgt ttcgcaatgg tggaaccatc ggtggagcag atattattgc taagttatta
    27661 gaagacaagt tagggctaca gctgaatcaa gctcttttag gcattgatct ttttgtcatg
    27721 attgtctctt tgacttatat ttccctgccg caaatgatgt atgctctgat tgctagcttt
    27781 atgtatggtc aaattgttcg cttggtacaa caaggtggtt attcagcccg tggcattttt
    27841 atcgtttcag aacaagcgga gaaaattgcc cggttcatca tggaagaatt gggaagggga
    27901 gttacttatc taacaggtga aggagcctac tctggtcgcc gtaaaaaagt gatttatgtg
    27961 gctttggggc gaagagatat tagggaatta aaagcatttt taactcaggt tgatcccaat
    28021 gcctttatca cttattttga tgtcaatgaa gtcaatagcc cagaattttt aactattaaa
    28081 agcaaatacc ataaaaagag aaaataaatg agcattagag ttgcctgcga agaatagtga
    28141 ggataaagga tggcacatca cgataaattg actaaactac taaaactgtt tttgattgcc
    28201 ctaggtgtag ccatttatac cttcggtttt gttaatttta acatggctaa tgctttggct
    28261 gaaggtggtg tggcaggaat aaccttgatt ttacacgcgc attttgggat taatcctgct
    28321 tactcttctc tcttatttaa tcttccactt tttattttag gggcaaagat ttttgggaag
    28381 cgttctttgg ctctaaccat ctatggaaca gttctgatgt ccgcttttat ctggatgtgg
    28441 caaaaagttc ctatcgaact tggcttggaa aatgacatga tgttggtggc tgtagtggca
    28501 ggtctctttt cagggattgg gagtggcatt gtttttcgct atggtgcaac cacaggtgga
    28561 acggatatta ttggttgcat tgcagaagaa aaatttggag ctaagctagg tcaaactttg
    28621 cttttggtgg atgctcttgt attgacagct tcgttgactt atgtggattt aaaacacatg
    28681 ctttacactt tggtgacaag ctttgttttt agccaaatga ttagtgtggt tcaaaatggt
    28741 ggttacacta tccgtggaat gattattatt accaagcatt cagaggctgc cgctcaagct
    28801 atcctaaccg aaatcaatcg tggagtgact tacttgaaag gtcaaggagc ttactctggt
    28861 aatgattaca atatcatgta tgtgaccttg aacccaactg aagttcggga agtcaaacgt
    28921 attttagctg gtttggatcc agatgccttt atctccatta ttgatgtgga cgaagttatt
    28981 agctctgatt ttaaaattcg ccgaagaaat tatgataaat aaaaatacag gtcaaacaac
    29041 ctgtattttt attttggtcc cccacttaag aaactaccaa gcataatagc tgagatagca
    29101 gttcccttgt aatggctagc ttttgttttt accaagcgac taagatcaaa tatgctttta
    29161 ggagcatcaa attgatgtgt taagatgtat tgattgataa gtgagtcaat ttttgtagct
    29221 aggagtgagc tcatcccctc tttttcaagt tgactggcga gctcgaagat cacttgacga
    29281 aaataatcat ctgcttgtat tacttgttcg ctataaactt tactaagagc atctaatatt
    29341 tctttttctg atggcatggc attctcctgt aacatattgt gctattatta taatataaaa
    29401 aactaagact gtcataaatg tgacagcctt agtaatgtta ttacttacat ttcatttggt
    29461 gcgtcaacac cgagtaagcg aagcgcttct ttaagaacag tagcagttgc atagcagaga
    29521 gctaagcggt tatcacgttc tgagttgtcg tcaagaatgc gagtgtgagc ataatatttg
    29581 ttaaagcttt gggctaagtt aatagcaaat ttagccataa tagaaggctc aaagttatct
    29641 gatgttcgct tgataatgcg tgggaaatct tggataagtt tgataatttc ccagctttca
    29701 gcatcagcta aactgtaagt ggtggttgca gatggcgtaa agtcagcttt acgtagaata
    29761 gattggatac gagcatgagc atattgaacg taaggtccag tttctccttc aaaggaaacc
    29821 atggcctcaa ggtcaaagtc atacccattc atacgatctg ttttgagatc gtaaaacttg
    29881 atggcaccga caccaacagc gtgtgcaaca gcttctttat cagcaagatt tggatttttc
    29941 gcttcaatct gggaagctgc acggttaatg gcttcagcaa ctgtaggttc aagaagaata
    30001 acattacctt tacgtgttga taatttagca ccgccttttg tgacaagtcc aaaagcaacg
    30061 tgtgtcatgt catctgacca atcgtaaccc atttctttta gcactgcttt taattgtttg
    30121 aagtgagcag cttgctcatt accaacaaca taaacggatt tagcaaagtc gtaagtgcgt
    30181 ttacggtaaa gtgcggcagc taggtcacgg gtaatgtaaa gagtagcgcc atctgatttt
    30241 ttgatcaagg cagggtgttc aatgccatat ttttcaaggt taacaacttg ggcacctttg
    30301 gattctacaa gaaggttttt cgcttctaat aagtcaagaa cctcatccat tttgtcatta
    30361 tagaaggcct caccgttgta actatcgaag gtgacatgta attggtcata aagtcggttg
    30421 aactcaagta aactttcatc acggaaccat tgccataatt cagtagcttc tttgtcgcca
    30481 tcttccaatt tacggaacca ttcacgagct tcttcatcga cggttggatc agtttcagct
    30541 tcagcattga tacgaacgta aagttttaag agttcatcaa taggatgtgc ctgaacagca
    30601 gtttcgtctc cccatttttt ataggcaaca attagcatac caaattgttt accccagtca
    30661 ccaaggtgat tgatttttac aggtttatag cccattttgg caaaaatgtg agcgagacta
    30721 tcaccaataa ctgttgagcg gaggtgaccg attgaaaatg gcttagcgat gtttgggctt
    30781 gacatgtcaa tagcaacatt tcgcccttga ccttcgtctt gctgagcata gtctgaacct
    30841 gctgtaatca cttgttcaag gacctgtgag gaaatcttag ctttatcaag gaaaaagttg
    30901 atgtaagggc cgacagctac gactttttca aattggctct catcaatctg ttcagctaac
    30961 tcgctagcaa tcatttgagg ggctttgcga aggacttttg ctaaactaaa ggctggaaag
    31021 gcaaggtctc ccatatcaga attttttggg gtttcaagca agttaaaaat agcatcttgt
    31081 tctaattctg gaacaacttt agctatttca cttgcgatta gagttttagt atccatacag
    31141 cgtctcctaa aaattgtttg ttaccctatt ctaacatatt tctttaaaat aaacgaggag
    31201 aggattgata aattatactg aaactttcaa ggaaatgaat tgcttgaggt tgttattttt
    31261 ctgaaaatgt tataaaaaga gaaatgaggt ttcttttcaa cagttttcaa gtgaaattct
    31321 agttggattt gataaaaaat tgctgaaaat agctgggcga agatgaaata atacactttt
    31381 tttgttataa tttgagagga taattataca attggggtga tatatcatga ataaaatgga
    31441 gcgtcaacag cagattaagc gaatcattca agcagagcat attggcacac aagaagatat
    31501 taaaaatcac cttcaaaaag aaggcattgt ggtcacccaa gcaactctat ctcgggactt
    31561 aagagaaatt ggccttttga aattgagaga tgaacaaggc aaactctatt atagtttgtc
    31621 tgaacccgtt gcaacaccat ttagtcctga ggtgcgtttt tatgttttga aagttgatcg
    31681 agcaggtttt atgctggttc tccataccaa tttaggagag gctgatgttc tagctaattt
    31741 gattgacaat gatgccattg aagatattct aggaaccatt gctggtgcgg ataccttgct
    31801 tgtgatttgc agagacgaag agattgctaa acgctttgaa aaagatttag ctgcaggcct
    31861 atgactagct atcaagagtc tttgacacaa ttgattcttg ctatccatga attctagtat
    31921 cgttgcttat aaagaagtgc agcaatagct gtctaagctc cgtgatttta aaaagtaagc
    31981 ttatcagatg aaacgctatc aacaagatgc cctgcttttc aaaaaaaaat agataaagaa
    32041 aaggctgcga cagtatctgc aagcagggca aaagaactag aagataggct cagtcatcag
    32101 ccattaattg atgattatcg agaaaagatg caagatgcaa gtgatgtgat tcagtatatc
    32161 accaaacgta tagaagatca gttaaacaag gagttaataa atggcaaaaa ctaacatttc
    32221 tcctggaatg caacagtatc tggacatcaa aaaagattat ccagatgctt ttttgctttt
    32281 taggatgggt gacttttatg aattatttta tgatgatgct gtcaaagcag cacaactctt
    32341 agaaattggt ttgaccagtc gcaacaagaa tgcggaaaat ccaattccca tggcaggcgt
    32401 gccacatcat tctgcccaac aatacattga tgtgttaatt gagttgggtt acaaggttgc
    32461 tgtcgcagaa caaatggaag acccaaagca agctgttggg gtggtgaagc gtgaggtcgt
    32521 tcaagtcata actcctggaa cggttgtgga ttcagctaag ccagatagcg ccaataactt
    32581 tttggtagct gttgactttg atggttgccg ttatggattg gcttatatgg atgtatccac
    32641 aggtgaattt tgcgtgacag atttggcgga ctttacgagt gttcgtagcg aaatccaaaa
    32701 cctcaaggca aaagaagtct tactaggttt tgatttatct gaagaagaac agacgatttt
    32761 ggtcaagcag atgaatttgc tgctttctta tgaagaaacg gtctatgaag ataaatcttt
    32821 aattgacggc caattgacaa cggtagaact gacagcggca ggaaaactct tgcaatacgt
    32881 tcacaaaaca caaatgcgag aactcagcca cttgcaagcc ttggttcact atgagatcaa
    32941 ggattatttg cagatgtcgt atgccactaa gtcaagttta gatttggtag aaaatgctag
    33001 gactaataaa aaacatggaa gtctctattg gctgttagat gaaaccaaga cagctatggg
    33061 gatgaggctt ttgcgctcat ggattgatcg acctttggtt tctaaagaag ctattttaga
    33121 gcgtcaagaa attattcaag tttttctgaa tgcttttatt gagcgaaccg atttaagcaa
    33181 tagtttaaaa ggtgtttacg acatcgaacg cttatctagt cgcgtgtctt ttggtaaggc
    33241 aaatccgaaa gatttacttc aattggggca taccttagcc caagtgcctt atatcaaagc
    33301 tatcttagag tcttttgaca gtccttgtgt tgacaaactt gtcaatgata ttgacagttt
    33361 gcctgagttg gaatacttga ttagaacagc cattgatcca gatgcaccag caactattag
    33421 tgaaggcagt attattcgta ctggttttga tgagcgcttg gaccattatc gtaaagtgat
    33481 gcgagaagga acaggttgga ttgcggatat tgaggctaaa gagcgtcaag caagcggcat
    33541 taataaccta aaaattgatt acaataaaaa agatggttat tattttcacg ttacgacttc
    33601 aaatcttagc ttagttcccg agcatttttt cagaaaggca actttaaaaa attctgagcg
    33661 ttatggaaca gcagaattgg ctaagattga aggtcagatg ttagaggcta gggaagagtc
    33721 atctagttta gaatacgata tttttatgtg tattcgagct caagttgaaa cctatattaa
    33781 tcgtttacag aaactggcta aaattttggc aacggtagat gttttgcaaa gtttagcagt
    33841 cgttgctgaa accaatcatt atatccggcc gcagttcaat gataatcatg tgattacaat
    33901 tcaagaaggt cgtcacgcgg ttgttgaaaa ggttatggga gtgcaggaat acattcccaa
    33961 tagtatctct tttgaccaac agaccagtat tcagctgatt acaggtccaa atatgagtgg
    34021 taagtcgact tatatgagac agctggcctt aacggttatc atggcccaga tgggttcatt
    34081 tgtggctgct gaccatgttg atttaccttt atttgatgcg atttttacgc gtattggggc
    34141 tgctgatgat ttgatttctg ggcaatcaac ctttatggtg gagatgatgg aagcaaacca
    34201 agcaatcaaa cgcgcaagtg acaactctct tattctattt gatgaactgg gacgaggtac
    34261 ggcaacttat gacggtatgg ctttagccca ggcaattatt gaatatatcc atgatagagt
    34321 tggtgctaag accatatttg caacgcatta tcatgaattg acagacttgt caactaagtt
    34381 gacaagtcta gtcaatgttc atgtagcaac gcttgaaaaa gatggcgatg ttaccttcct
    34441 tcataagatt gctgagggac cggcggataa atcttacggt attcatgttg caaaaatagc
    34501 aggactgcca aaatccctat taaagagagc agacgaagtt ctgacccgtt tagaaacaca
    34561 gtcacgatct actgagataa tgtcagtccc tccacaagtt gagtcaagca gcgctgttag
    34621 acaggggcaa ttatcccttt ttggtgatga agagaaagct catgagatta ggcaagcact
    34681 ggaagctatt gatgtcatga atatgacccc gcttcaagca atgacaaccc tttacgaatt
    34741 gaaaaagttg ttatagtttt tcagctgaaa atgaaaaaga tgctttctat attgaaggca
    34801 tctttttgtt ctgtcaaaaa cggtccgagg ccttcggcta tttattaagt gtgttataat
    34861 agtccataag aatgcgagga aattatgaca aacattattg gacttgaatt ggcagtcttt
    34921 acaggctatt gacagtcctt aagcattgat atgactgttt ttttgaaaaa atataggttt
    34981 taagtttcct tagacttccc tcaaaagtcc acaaaaaggt gaacaaaaaa agacctttac
    35041 aggtccttta cacaatgagt tcagcaggca agaactagcg tagtttaaat actacgcttt
    35101 tagtttgccc tatggtttat tatagcatat attagctcca ccagctttta aaccagttaa
    35161 ttggattaac ataatatttg aaaccttcac aagctttatt aatgcgagat tttacacgtt
    35221 gagtccatgc ttgtggctcg tcagtcgaca gtggacttga ttcttcattt acagtagatt
    35281 ggttttgggt atctgaagct aaatcaacag cgttagaagg cttagcagta ctttcgctta
    35341 atatattttt aattcctgat ggatgttttg tagtttcgga gctttcggat tcacttttat
    35401 tctcttcacg tcacggctgg ataatatttc tttgactgga atatgatata ccttggtggt
    35461 aatataatca tgaccgtcgt cgaatatcct tattgctact cgatctcctg tatccaaggg
    35521 agattttagc ttcacagtat agtcgcctcc tccgttagct cgatacccac tgatttgata
    35581 agttgttttt ggacattctt gaccgtagct gtattttgat ttttcaagcg ctgagcactc
    35641 tctttcaaca gttatagctg agggcttttc taccttatct tctttctttt cgttacttgt
    35701 agaagttgtt gaggcatata catagccata agggacattt ggaatattta atttaatact
    35761 ttcatcccct actttgaacg gagcaactat aactttttga gagtcttctc catcaacttc
    35821 aaaaacttta ctgtgaatat tctctacaga tgtagataca gcattatctt cttcctccgc
    35881 cttcacattc gtggctacac caaccgtaag caacatcaca gctaacatta atttcttttt
    35941 cactatattc tccttaaact taaatatcga cctccatagt accagttaat cagtcaaaaa
    36001 atccactcta ctttttgaca ttttatgtct aatttgaccc gccaagtcag atttgcaaac
    36061 gataccaagt tcgtttcttc taatcgttat tttctagatg gatgtgttaa ctgtattaga
    36121 gacgtattaa tcttaaacca ttgtcataaa cgaacattat tttttagcac tccatccctg
    36181 taaaattcca caaactcaag caaggctctt ttcttggtct cataatacca actttgactt
    36241 cttttaagtt cttccataat gtcctgttga ggttttttct caccgatcaa gtaacactca
    36301 atcagtatct ttctatactc tatcttagac aattgattaa tggcatacct aatagcgttt
    36361 agctcctcta gggcgcattc tcggcttatt tcaaggtgtt ttctgcgcgt gggatggtac
    36421 tctatatcaa actggtaaag ctcggtataa gttaaatcaa ggctattagc gatacgttgc
    36481 catctatgga attctttcag cttacgaata gcgttcttct tgctcatcta acacctctaa
    36541 agcttctcta tgtagtttga acacagtgtt tcttgagtaa cctagtttat cgagtatctc
    36601 gtcccaggat aagtcatcca cgtatctagc tttaataaca gctatctgtc tctcatcttg
    36661 gagtgtggcg atcatggcta gtctcttatc acgttcttta gctaaatata agagttgttt
    36721 agctgtacct ttttcgatat gtcttattgc ttcaggatta tgaaaagcat ttatcagctt
    36781 gatgtcttta tctcgttgtt cttcaaataa ggttattaaa gcgaaaagtg gtttcaattc
    36841 tttaagttgt tctttagcgc tcatggtctt ttctcctggt tatggtataa tttatttaag
    36901 cttaaattta accaaggggg cgttccgtgt ggacgtcttt ttgttttgtt cattttgtaa
    36961 actagatatt ttttgtagta cttcgctttt ggcttctaaa atcgttgcta agcacttttt
    37021 agagtttata gtataaatca tcaacttagt agctagaagc gctaaaacaa tgttttattt
    37081 tagtcttaga tggttattct ttgtggcagg gttatgggct aaaatgagat gtcaaatcct
    37141 ttcatatcaa gtttttaatc ttcggtgaaa atttcaaaaa gggaattttt tgcacagaaa
    37201 agggcgcgtt cttaagtttc cgaacaatat agccccgttt aaaaatgaag ggggtagttt
    37261 ccgaatatta tagccagtac ctgtcaccct tatccatata gtaatgaaat cttctccagt
    37321 gataaaggta tttggttaat ctcatgtact ttggacgttt aggaaagtca tcacgactat
    37381 aatatccatg aatgtgtctt gcttctggat ttactttcaa acactcttta aaggctaatt
    37441 gccagtagta gcaacagtct gtcttgcttc gattgagcgt ggcttgatga accttctgac
    37501 aagaaccaca agcaaaggca tgagaagcct taaataattt ccgacaacgt ctctcacagt
    37561 caggacacac gaaaaagtaa cgtttaccac cataagttcc tggaatcgtt tcaagcaata
    37621 ggccttgacc attgtagtga atcactagcc catctaggtc tatgcggata gcttggtcac
    37681 ctattgatcc tgtaactctt gtcttcccct gtgtcttcat tggtttaatg atattttcaa
    37741 tagatagttc taacattctt tctccttaaa actcaaacaa cccaaaacta ttgataaaac
    37801 gacaagaaag agggaaaaac ctctgaatgt ctatttaacg agtaactgat cttcaacaac
    37861 catatcatac aaatggttaa aggcttgact gatagactca aggatggccc ctaagtcttc
    37921 tggtgtcatc tctttataat tcatagagag gtgttcagcc agttggttgt gatcggagat
    37981 gaaggctata agtgtgtctc gattattaac tttcccttga gtacttttag ataaagaaac
    38041 cacgcgctga tgatcaagtt cttcatccgt catatcctca ggttggttgt aatagtcctt
    38101 gaaactatca cagatacgct tgaagacctt gcttaacttt ctgtcttcag catattttaa
    38161 gactaactga ttagcatgac caccttggtc atcattgtga taagttgcgt caatcactgg
    38221 ttgctcatag gtcccagtca tatagcctaa aatagcatgg caggctactt gtgcggtatc
    38281 aaagtcttta aacgtgtagt ggaatgtgaa tgtctttggt gtgtctgaaa atgttctcat
    38341 gctatttctc ctttgtgatt gctataatgt ctgataaatt gatgatggca gaaggacatg
    38401 ctacccagtt tggctgttgg ccagataaaa gatatttgat caactcatta taaagggtgc
    38461 ggtctccttg tatggtgatg gtgttaccac ctcgtgtgtg taattttagt ttcatatcag
    38521 ttacctgtac aagaccaata aagaagttgt ggtactcatg tcttcatagt tgccataagt
    38581 ggcttctgaa aatttgatgt ctatcacaga taccgatagg gtaaagagat tgacccgata
    38641 ttcaaaatca tctagtgatt cattgtgttt ttgataaaat agtttgattt tcattatata
    38701 acctccgaat tttatacgtt ttatacgttt ggtttttcaa acgtataaaa tttaaagtca
    38761 gccgtatcaa gggtttaagt ctctttttat acgttttata cattttatac gttaaattta
    38821 aaaagtgtat ataaggattt tataagggct atttattaat actctatacg ggaaattttt
    38881 aaaataacgt gttaaacgtg ataaacgtat aaaccccttg atatgactgg gctatttctt
    38941 tatacgttta attttttaaa tgctaaaacg tataaaatga ctaagttttc ttttgttttt
    39001 tgtgcgtcgg ccaatgattg taatatccac gttcattctt tggctttttc cttttttcgg
    39061 gtgatgctct accgttagcg taagatgcgc tagcaaacag aggtagatct tctttaggat
    39121 aaaaacctgt atggagctgt cggcctactg gtatgacctt ctggcctgct tcaaaccctt
    39181 caggaagatt gcttttgatt tctttatgta accctctttc tgattttatt tgtttgatgt
    39241 catagtattc taaaaagcct ttccaaacat gatagacaaa gctattagga ataaattcgc
    39301 tggtgagctc atccgtgaag aacttagaaa cgaagtcaat aactgggttc atctctttat
    39361 ggtgttcttc cagtatctca atagatgctt ttggattaat gtcagtgatt ggtgtttcaa
    39421 tcgctagctt aagtaagtac tcaagaactt ctttgcgatt aatataatca tttctgatag
    39481 ctttgttggg ctttccttta aatactttgg taaaaggtaa aatcctaaag cgtctatcaa
    39541 tggcggactt atcaccgttc attcgtggta aaccgttgga agattgtacc acagtcatgt
    39601 ttaaacggat actatatggg cgtttcccct tgtcctcaat cgtcataatg tcacccgtgg
    39661 ctaaactaaa tatatcagac gtatctttga taaccgcgtc tttttgaata tcatcaccaa
    39721 ttacaatgga tttccctaga agtattgaag tagtaaagcg actttttgct agctctgtta
    39781 ttttaaggct tgccacgtta tccataccca ctaaattaat gagtaattgc tgaaaagtcc
    39841 cttttcctgt cccaccttca ccgaataacc agaagatttt ctgtaaggat tgacctgtga
    39901 tgctagcttt aataatctga atagcaaggt tataaagttc ggcgtcaccg tcaaacaatt
    39961 ctaagagcca agcagtaggt ttccagccct ttattgtggg ttctttagct ttcttattgt
    40021 aacccgtctt aattttgcga gtgacggtta tatctggagt taattcttca aattgaccag
    40081 ttttataatt gtagagctga tttccgataa ctgtatattc tctttgaatc tccttcagtt
    40141 gactttgcct agcaattttg taaagtgtgt caaaagcttg tttttcagtc gcgtttggga
    40201 aaataactga aatgagatct tgtaaaaact cattatcttc tagccaaacc ccgtgatcag
    40261 gatgaaaaaa gtaaagtggg gctttttgtc cttgagcttc aggtttaact cgaataaagc
    40321 ggagatagtg tttgagcata atagccacgc ccaaaggtgt tttaggtaaa gctttttcac
    40381 tggcttcttg tcctttttct ttagctaatt cttcatgttg tacctcggtc aatctacccg
    40441 cttttacgtt ctcaaggtgt ttgctatcag ccataacgcc atcataggca atcttgaaag
    40501 cttcatcttt catctcttga cattccttga taagctgacc tctaacacct ttgaaagtgc
    40561 tgaaatattt atcttcattc tcacgcgctt cagtgatttc attttctaag tttttcaaat
    40621 cttcttgctc tatggttcta ccctcttttt ctgtattctg ctttagcaat gctggtaaac
    40681 gtcctatcta tctcatcaat gggtagtggc ttagttgtca cgctgttagc tatttgtacc
    40741 agctcataag ccgtctctaa atcacaatcc acccatttat taaatagcaa gccaacaaac
    40801 ttagttaagg tcacgttgcg cccgccttcg tctccaaaac cattaaacaa ggtatctatg
    40861 accctcatgg taatagaacg ctgacttcta gggcgtggcg tgtaagtagt aacaacttgt
    40921 ctgtttggcg tgctaccatt tttaggaaca ggataatcaa gaccacggtt cacatagcgc
    40981 tgatagtcct ctgggtcgcc tgttgtaaca ggtaagcctt gtaattgtga ccaggtaagg
    41041 ctagctaaat caaacggcag tccaatctta tcggctatct ccttgaccac ttgttgataa
    41101 gtcgcttcag tcatcacgtc actaggcttc atgacaaggc gataacgggg cttctcgggg
    41161 gtgtgtttaa tcgttggata aataatataa ctatactccc aaagcgtctc agaaacgatt
    41221 ttaggtaggt tgacgcctgt ttctatctcg tcatagtcaa gaaaaatcaa atcgcgataa
    41281 actaaactag cattattgcg cttatagcta ccgtttttct ctgctgtgac cttgccactt
    41341 aggcagtagg gggcttgtgt tcgcttgtat tcttcaatat caatatcctc aggcggtttc
    41401 aaaggtttaa actgagcaat atagtcaaat ggttctaact gtcctttgta ggggtacaaa
    41461 taagagctaa agcctcttgc ttcataaata gtcatctaca catttacccc caaaaagata
    41521 agaatatcac tgaccttgta ataatgtttc ctggtgtctt ctagtggtgg ttggtatcgt
    41581 cttaacccag cattttccca ccgttttagg gttttacctt tgatatttaa ttcctctttg
    41641 acttgttcgg ccgtgatcaa ccctaaaact cttggtttag gtttctggta ggcttccaaa
    41701 aagcgattaa aagcggtcag gttttgttct aagagtttgg cttcataatc ttgactaaat
    41761 aagctcatgc ctaacctcct ttgagtaatt ccttataact ggttaaatcg gcattcaata
    41821 acacacttag gcgttcctgt tccttttgta cttgattata aaaggcttta gcaccatcta
    41881 gtaattcttc tttgttagct gggataaagt acccacgatt gaatccgtgt ctaatgccga
    41941 taatagggat gttatagcgt gtgattaagc tactgatgat actttggacg gaacgctctt
    42001 caagtttcag tattaagcta atctctgccc ctgtaatggg gttgtctgct ccaaccttga
    42061 tcagattaag gacacgtcta taattctctg gtagtgtcat ttcgtgtcct ccttatcatt
    42121 tggaaacagg atttggttat caataacacc aagcacttga tttttaagac tatcttttaa
    42181 ctcgttcaat gcttgtataa ctatatttag ccctttttta tattccatct ctattggtat
    42241 tgattccaaa aatttaacaa cggcatcagc tttgttatag tcacgttgtg tagtattgat
    42301 aaatattttt ttcgtgaata acggaaaatc gtcccactct gcttcaatat cttcatctag
    42361 cattttgata tttttgtcta aaaccctatc actcaaccag tttgtaggct gtttttcgct
    42421 atcttctagc aattttttaa aatattcttc cgttgtcatg cagttccctc cctaattgta
    42481 ataatggttc tgtgattgaa tataagcccc atagtttgcg ttctgacgtg gtttagggac
    42541 ttgggtatct tctggtaaat caatgtctat taatgactta gaaaggctaa gaagaagccc
    42601 taagagacct aaaacaaaga atagaataag cgtctgtgtt ggtgtgaggt taagttcttg
    42661 catcatgccg atacctcact taaataagtt tctagttccc ctgagtcttt ctctgaacaa
    42721 ggtaaaccgt taacggctct aaagacaatc tctgtggttc gttgatagtc taaagcgtcc
    42781 catgcttctt caaagctggt ggcacttttt ctgaatttaa tgacgtactc tgtcataacg
    42841 ttagcaataa ttacccaagc gatatgttgg ttatatagtc gagtgaaata ggcttctgct
    42901 ttatttttgc tgagttggcg atttttgaac atttctagct gttcaggagt gtatctatct
    42961 tttgaaaaag gatttgtttc tactctatat ttcattatgt tttttctcgc ttaattatta
    43021 ttttctgtgt agtgttttta ttgattgctt gtttcttata ctagattcat gctagtttta
    43081 aggggtagct ccctacgtat ggtcaaaata gcttcaatat gctataatat aagatataaa
    43141 acccttttaa taacagcttg cctgctttat taattgagtt tagttatact agttgaaggc
    43201 ttggaagttt ggtcgctgtc aaagcctttt ttgttgtttt cacgcgcatt gtagcgtgtt
    43261 ttttaatgcc attgtcttaa tatcttgata ggtaaaatta agattgataa gagcgattgc
    43321 catatcttct aaagcagtgt actgtgctag ttcaattgag tttaagcagt caatatcaga
    43381 ataaccacct ctggttactt ttaattgctt gctattctta ccagtaacag ctttaagcaa
    43441 tagattgtac acagtcggat aagccatttt aggcgcgtgt tcccatgtct tgatagcttc
    43501 attaagtgtt tttcgtttag gagcttcaag agaacgctgt aacctaattt gagtgagttc
    43561 ttctcgcatt tcaaagaatg ccttgactag gttcttttta aactctctga ctggttcggt
    43621 atttcctaga taggtaacta ataaagtcgc ctgctgttcg tttaagtgat aaattcttct
    43681 aggtcgtccg cctagtgaac ctttttcagg tttatggatt tcaaatgaca aaaccccaaa
    43741 cgcttctaaa aggtaacgca tggtcacgca aagttacgca gaattttcca tgttgcgtaa
    43801 cctactcaat ctctttagta ccaatcgatt tcagcattta tttaagaaag gttacgtagt
    43861 aaaaaaggag gtgcgttacc ttatgtacca cactactgca ctttcgttct taatcctttt
    43921 tatgcttatc aatcagcttt ctaactgaaa taatgtcaat ttcagcatgt tcagctatga
    43981 tgtcgtgtgt ggtgtaagga tctttcttac catccatgta aactaggttc atggtaatcc
    44041 tcctttatcc atagagttcc gttagttctt taaaatactg atcaggaatt tcatccatag
    44101 ccacttgttg taattgaatg gcctttaaac gattggtgtc gctagcagtc ggtttattaa
    44161 taatttcagc cgttgcctgt acttgcttga aatactcttc aagcttaagt tgccttcctg
    44221 cggaaacttc ttcggatatg gcttttctgt tattgataat ttcaaaggta tcaatttcac
    44281 cgtttgccat ggtgtaagca atgttatttc gataccgcca agctgccagc ctaagcttga
    44341 tgtctttttc agaccaatcg ggaagccgtt cagcaatcag ctctaggctc attgttcctg
    44401 tatcgtcaaa tatctgatgt aataattctt gtgtaaatgg tgttctagcc atttgttatt
    44461 tacctgcctt tcttaatggg ttgctctact gtaaatagcg tttgaaacac tgataccaag
    44521 gtcaaattta tccttgatta ccataagttc aacggtatca tctaataact gctctctatc
    44581 ttttaacatt tgttcagtca tttgagattt gctaatcatc tttggtaacc catacttatt
    44641 agataccgct ttattggcaa tcgtgttggc tttgataagg tcagtctgtt taacctgttc
    44701 taagccatta acaagcctat tcattgcctg cttctgatgt tctttatcaa acattctaaa
    44761 tacttggaag ccctctaggc ctgtgctttg gcgtagttgt ttgataatct caaataccca
    44821 taatttaaag gttttggctt ccttcttacg acttgagaag atagtttcat aaatgccaaa
    44881 ctcattaacg attaacattt cttgttgacg ccctaaactg tctgcgacgt ggttgtttga
    44941 aacaacctca tctcccaaac gttgtttaat aaattttgga ttcagatcta gtgctttagc
    45001 aatatcagct agcaccgccc accattcgcc attatgctct acaaatcgga tagtatatcc
    45061 gttccatgtt tctgttctca ataagttgtc ctttctagtc ttcaactgtc aatagttcat
    45121 caagtgtaac atttagacac ttggcaattt ttagcaatgt tttactatca gggttttctg
    45181 ttctctcata gtaaagtgcg gttaaagtag ttttagaaac ccctgtagct tcgtggacgt
    45241 ctgaaatctt tttacgttgc cttgctaaaa taactcttag attatttttc aaaatatcaa
    45301 cctccttttt tgatgtttga tatattttag tgttatcact aacaaatcac atactacact
    45361 actctaaaat atttgtcaat actttgttat atttttttga tgtttgtttt tttaaataat
    45421 gttagttata atttaagtac ggaggtctaa aacaaatgat taaaacaaat tttgctgtct
    45481 taatggccga acgcggcctt aaaatagcag atgtttatga agatactggt atttcaaaaa
    45541 ctacactcat ggctttatca gaaaacactg gtaaaggggt gcaatttgat acagttgata
    45601 aattgtgtaa ttacttggga atagaattaa aagatttctt tgtttatagt ccgtatattt
    45661 ggaaagctta taataaagaa gattatgaat acaaagaaga aggggataat cttatagcta
    45721 taaacctcaa atctacccat agtgaaagag tttatatact caaactattc tttttctcac
    45781 ctaaacacat tgattcacct actgacgaca caactgttaa actttgggta cgtctgtcat
    45841 tggatgaaga tagcggaaat tatggatata atgagtttta tgactttata tcttccttac
    45901 caatttcttt tcaaacgcat ttttataatg atgtaattga agtattaaaa aaacactacc
    45961 ttaattctgg ggcagtgatt tctgcatatc gatatgattt ccatccagac aaagagtatc
    46021 tttctgaaat tgttttgaat aaaaatgaca aggtcattgt ttcatttttt gatagttacg
    46081 ggaacagtca tgctcctaaa gcaatccaaa tagataaact tatcaaagta gactaaccca
    46141 cgcgccactg tatagaaaag tatgtacaca atccactctg agcgcgtgct tccctcgtgc
    46201 ttcagcaagt ccgctgacct tgtataaacc ttgtcacttt ttagggtgga aaaaagtccg
    46261 attttctgaa tactatacgc taaaaatatc aactgatttt agaagctgtc acagcggaaa
    46321 aagtaaatta ataaacgacc gatatatcaa gttctttaag tgaatttacc gagcgttttt
    46381 agaactattg aaataggttg acgtattatg tcagtacgtg ccaacatttt ccagcattcc
    46441 gaaatgcgac catgtgttcg tgtttgggag tagtaacctt ctattctcta agttcgctcg
    46501 aagttcagca ttatgcgcgt ggaacaaatt tagctacctt acagttacca ctcaataacg
    46561 acctgttaaa ttttcatgtc taaatgccaa ttttattatc tttacctacg cgcaaatacc
    46621 ttgatacgcc tttaattttc tttaattaca agaccttcaa aacttgacaa aaattgaggt
    46681 ataatctgaa cttttctgaa ctttttgtcg gcggtaatta aaaaaactgt ctgcgcgtgg
    46741 tcagtggttg cataaagcat tataaattct tgcataaaat tatttttatt cattttggta
    46801 acactaagga atgctaagag cgctaaagac tatactttct aactataccc tttgacttct
    46861 ttatcaaaca aagctataat ggacatagaa aaaggagatt gcgcaaacaa tctcctgtgg
    46921 caacaccgtt taagacggca gccttaccgt atttgtttat attttctata aaccgtccac
    46981 gattggctaa agtgtgggac ggtttttcta tttgttcttg ttattcatga tagctactat
    47041 cagagtacca aaagcaatca tcaaagtaag cgtttcataa actgacaaac cttgtcgtct
    47101 cctttctttt ggtttctgtg acttacatac ataagcacca cctccagaca taaggctacg
    47161 actaccgttt tttactttgt tacgaggttt attgtatcat agggacagac attttcaaga
    47221 gctcgaatct atgtaaacct tgacctagtt tttagacatg caaaacttct tcttaaattc
    47281 tctatacctt acaaaaccaa acaaaaaaga ccccgcaagt tttccacgct cgcaaggtct
    47341 taaaaagact aatattatac catgattttc ttttataata attcggatat ttacccgata
    47401 ccattattac accatgatat gaactaatct aaaacccttt taataatagc ttgcctgctg
    47461 atggaaaggt ttatgatcat gaaaataaca gaacataaga agaaaaacgg tacaatcgtt
    47521 tatcgtgcta gtatttatct aggcattgac caaatgacag gtaagagagt aaaaacaagc
    47581 atcacaggaa gaacaagaaa agaagttaat caaaaagcca agcacgcgca gcttgacttc
    47641 ctatctaatg gatctacaat taaaagaaaa gttgtgatta aaacatttaa agaacttagt
    47701 catttatggc ttgaaaccta taagttaaca gtaaagcctc aaacttatga tgctactgtt
    47761 actagactta atcgacatat tatgccaact ctgggcaata tgaaggttga taagataacc
    47821 gctagtgata ttcaaatgct gattaataga ttatctaaat attacgtcaa ttatactgcg
    47881 gtacgttcag tcatccgaaa agttctccaa caaggagtat tgctagggct aatagattat
    47941 aactcagcaa gagatattat ccttccaagg aagcagccaa acgctaagaa aaaagttaag
    48001 tttattgatc cgtctgattt gaaatctttt ttagaacatt tagaaactag tcaacacaaa
    48061 cgctataacc tttactttga tgcagttctc taccaacttt tattatccac tggcttgagg
    48121 ataggcgaag cctgtgcatt agagtgggga gatattgacc tagaaaatgg tacaatagcc
    48181 attaataaga cttacaataa aaatttgaag tttttgagta cagctaaaac ccagtcaggc
    48241 aatagagtga ttagtgttga taaaaagacc cttagaagcc taaagctcta tcaaatgaga
    48301 caacgacaat tatttaatga ggttggtgcg cgtgtgtcgg aggtagtgtt tgccacacca
    48361 acacgaaagt attttaatgc ttcggttaga caaagcgctt tagatactag gtgtaaggaa
    48421 gcagggattg aacgctttac ctttcacgct tttagacaca ctcacgctag tttattgctg
    48481 aacgctggta ttagttataa ggaacttcag taccgtctag gacatgcgaa tatcagcatg
    48541 actttggata cctatggcca tctttctaag gacaaagaaa aagaagctgt tttatattat
    48601 gaaaaggcta tgaataattt ataagtccac aaaaaagtcc acaaattaat attttgagag
    48661 gtgtaaacct aatgaaacct tgttatatca acgtttagaa agtgttaaaa acaaaattat
    48721 gacaaacatt attgaattac cggaagttct cgccaaccaa attgcagctg gtgaagttgt
    48781 agaaaggcca gcgagtgttg tcaaggaatt ggttgagaat gctattgatg ctaaaagtag
    48841 ccagattacc gttgaaattg aagagtctgg ccttaagatg atacaggtta cagacaacgg
    48901 tgagggaatg tctcatgaag atttaccttt aagtctgcgt cgccacgcta ctagtaaaat
    48961 taagagtcag agtgatttgt ttagaattag aacacttggc ttccgtggag aggctttacc
    49021 gtctgttgcc tctatcagta aaatcacgat aaaaacagca acaaaagaag tcactcacgg
    49081 ttctcttctt atagctactg gtggggaaat tgagacactt gaagcgatct caactcctac
    49141 tggaaccaaa attaaggttg aaaacctttt ttacaacacg cctgctcgtc tcaaatacat
    49201 gaaaagttta caggcagaat tagctcacat tgtagatgtg gtcaaccggt tgagtttggc
    49261 acatccagaa gttgctttca cactgattag tgatggtcgc caattaactc agacatcagg
    49321 aactggcgat ttacgccaag caattgcagg gatttatggt ttgaatacta ccaaaaaaat
    49381 gctggctatc tctaatgctg atttggattt tgaagtttcc ggctatgtta gcttgccaga
    49441 gttgacacgc gccaaccgta attacatgac gattttggtt aatgggcgtt acatcaagaa
    49501 tttcttgctt aatcgagcaa ttcttgatgg ttacggttct aagctcatgg ttggacgttt
    49561 cccaattgtt gtgattgata ttcagattga tccctatttg gccgatgtca atgttcaccc
    49621 cacaaaacaa gaggttcgta tttcaaaaga gcgtgaatta atggctttaa ttagcacggc
    49681 tatttcagag agtcttaagg aacaagattt gattccagat gctctggaaa acttagccaa
    49741 atcaagcaca cgacatttct ctaaaccaga gcaaacacaa cttcctttac agtctagggg
    49801 actttattat gatcctcaaa agaatgactt ttttgtcaaa gagtcggctg tttctgaaaa
    49861 aatacctgaa actgattttt atttcggtgc tgttgacaac agtgtaaagg ttgaaaaagc
    49921 agagctgtta ccccactcag aagaagttat aggaccttct tcagttaaac acgcaagtcg
    49981 tccccagaat acctttaccg agactgatca tcctaatctt gacttaaaaa acagacaaaa
    50041 gttatctcaa atgttgaatc gcttggaaaa tgaagaaaaa tcagtatttc ctgaattgga
    50101 ttattttggt cagatgcatg ggacttatct ctttgctcaa ggtaaagatg gcttatttat
    50161 tatcgatcag catgctgctc aagagcgggt taaatacgaa tattatcgtg ataagatagg
    50221 tgaggttgac agtagtttgc agcaattgtt ggtgccctat ttgtttgagt tttctggttc
    50281 tgatttcatt aacttacagg agaaaatggc actcttaaat gaagttggta tcttcttaga
    50341 agtttatggg cacaatactt tcattttgag ggagcatcct atctggatga aagaagaaga
    50401 gattgcatct ggtgtctatg aaatgtgtga catgttactt ctaaccaatg aggtatctat
    50461 caaaacttac cgagcagagt tagctattat gatgagttgt aaacgatcta tcaaggcaaa
    50521 tcatagcttg gatgattatt cagcaagaaa tctgctactg caattggccc aatgtcaaaa
    50581 tccttataac tgccctcatg gtagacccgt attgattaat tttagtaagg cagatatgga
    50641 aaaaatgttc cgtcgaattc aagaaaatca cactagcctg cgagagctag gaaaatatta
    50701 gagaggatga gatgcaagag tttttaaacc ttcctaagca gattcagctg aggcaactgg
    50761 tacgctttgt gaccattacc ttaggcagta gtatctttcc ctttatggcc atgtattata
    50821 cgacttactt tggtacgttt tggacaggcc tcttaatgat gattaccagt ttgatgggat
    50881 ttgttggaac tttatacggt gggcatctgt cagatgctct tggtcgtaaa aaagtcatta
    50941 tgattgggtc agtaggaaca acgctaggct ggtttctgac tattttagct aatttgccta
    51001 atgcagctat tccttggtta acctttgcgg gtattttatt ggtagagatt gcttctagtt
    51061 tttatagtcc tgcctatgaa gctatgttga ttgatttgac tgatgagagt aatcgtcgat
    51121 ttgtttacac catcaattat tggtttatca atattgccgt catgtttggt gcagggctat
    51181 ctgggctttt ttatgaccat cattttttag ccttgttagt agccttatta ctcgttaatg
    51241 tactttgttt tggcgttgct tactactatt ttgatgagac tagaccagaa acacacgctt
    51301 ttgatcatgg taaaggatta ctggcgagtt ttcagaacta ccgtcaggtg tttcatgatc
    51361 gtgcctttgt cttgtttacc ttaggtgcca tcttttccgg tagtatctgg atgcagatgg
    51421 ataactatgt gccagtccat ttgaaactgt attttcagcc aacggctgtg ttaggtttcc
    51481 aagtaactag ttctaaaatg ttatcattaa tggttttaac taatacaatg ctgattgtcc
    51541 ttttcatgac agtagtaaat aaattaacgg aaaaatggaa actattacct cagcttgtgg
    51601 ttggttcttt actatttact ctagggatgc tcttggcatt tacctttacg cagttctatg
    51661 ctatctggtt atcagttgtt ttgttaactt ttggggaaat gataaatgtt cctgctagtc
    51721 aagtcctacg tgctgatatg atggatcatt cccaaatagg atcttataca ggttttgtgt
    51781 caatggcaca acccctaggt gctattttgg ctagtctact agtatctgtc agccatttta
    51841 caggtccttt aggcgtgcaa tgcttatttg tagtcattgc tttgctaggg atttatttta
    51901 cggttgtttc tgcaaaaatg aaaaaggtgt aatatgtacg attatattaa aggtcaattg
    51961 accaaaatta cggcaaaata cattgtcgtt gaagctaatg gattgggcta catgattaat
    52021 gttgccaatc cttatagctt tacagatagt gtcaaccaac tggtaactat ttacctgcat
    52081 caagtgattc gtgaggatgc tcacttgttg tttgggtttc atacggaaga cgaaaaagat
    52141 gtttttctga aattaatttc tgtatcaggc attggtccga caacagctct tgctattgtg
    52201 gcagttgatg ataatgaggg acttgtgaat gccattgata acagtgacat taagtaccta
    52261 atgaaatttc ctaaaattgg taaaaaaaca gcgcagcaaa tggttcttga cttagctggc
    52321 aaatttgtgg aggctccaca agagactggt cataccaaag cgcgcagcaa taaagcaggc
    52381 aatactcaac tggacgaagc gattgaagcc ctccttgccc tcggttataa agcaacagag
    52441 ctgaaaaaaa ttcgtgcctt ctttgagggg acctctgaga cggcagagca atacatcaaa
    52501 tcagcattga aactgttaat gaaagggtag gtgtttcaca tgaaacgttg ctcatgggtt
    52561 cctaaggata accagcttta ctgtgattac cacgatttag aatggggtca acccctggat
    52621 gatgatagag atttttttga attgctgtgc cttgaaagtt accagtcagg cttatcctgg
    52681 ctgactgttt tgaaaaaacg ccaagctttc agaactgttt ttcatcatta cgacattgca
    52741 tcggttgcaa cctttacctc ggaggaaatg gctgatgctt tagagaatcc atccatcatc
    52801 cgccacaagc taaagctagc agcaactgtc aacaacgcta tcgcagtaca gaaaattcaa
    52861 aaagagtttg gtagtttttc aacttatctc tggaattttg ttgggggaaa gccaattaac
    52921 aaccttgtca atcaagagaa tcttgttctt gctcaaacag aattatctat tcgcttagct
    52981 aaggatttaa agaaaagagg atttaaattt ttagggccta caacggttta ttcttttatg
    53041 caagcatcgg gtctggtaaa tgaccatgaa gaggcttgtg ttttcaatag aatcttctaa
    53101 ttcttcgtga gttggaagat tttttgataa aataagatca gattacgaat agataagtag
    53161 gtggggaaat gaaagctgaa ctgattgcag taggtaccga aattttgact ggtcaaattg
    53221 tgaataccaa tgctcaattt ctgtcggaaa aaatggcaga gctaggtatt gatgtctatt
    53281 ttcaaacggc tgttggggac aacgaggagc gtttactttc agtgattaca actgctagtc
    53341 agcgtagtga cttggtgatt ttatgtggtg gccttggtcc aacgaaagat gatttaacca
    53401 aacaaacttt agcaaagtac cttaggaaag acttggttta tgatgagcaa gcttgtcaga
    53461 aactagatga cttttttgct aagcgcaagc cttcatcacg gacaccaaat aatgagcgac
    53521 aggcacaagt gattgaaggg tcaatccctt tgccaaataa aactggtctt gcggttggtg
    53581 ggttcatcac agtcgatggt attagttatg ttgtcttacc gggtcctcca agtgaattga
    53641 agtcgatggt aaatgaagaa ttggtaccac ttctgtcaaa acaatacagt acattgtatt
    53701 caaaggtact acgctttttt ggtgttgggg aaagtcagtt ggtaacagtt ttgtcagatt
    53761 ttattgagaa tcaaactgat ccaaccattg ctccgtatgc taagactggc gaagtgactc
    53821 ttcgcttatc aacaaaaact gaaaaccaag ctctggcaga taaaaagtta ggtcagctag
    53881 aagcgcagct actatcccga aaaactcttg aaggtcaacc cttagctgat gtcttttatg
    53941 gctatgggga ggataattcc ttagcgcgtg agacatttga gctcttagta aaatatgata
    54001 agacaattac agcagcagaa agtctaaccg cgggattatt tcagtcaact ttggcgagtt
    54061 ttccaggagc ttctcaagta ttcaatggag gctttgtggc ttatagcatg gaagaaaaag
    54121 cgaaaatgct aggccttcct ttagaggagt tgaaatcgca tggcgttgtt agtgcttata
    54181 cagccgaggg gatggcggag caagcaaggt tattgactgg tgctgatatt ggggtaagtt
    54241 taacaggtgt tgccggacca gatatgttgg aggaacagcc tgcaggtaca gttttcattg
    54301 gccttgccac tcaaactaag gtagaatcaa taaaggtttt gattagcggg caaagtcgtt
    54361 tggatgtgcg ctatatcgcc actttacatg cctttaatat ggtccgtaaa actttattaa
    54421 aacttgagaa tttgctataa tgttatttag tagctatagt aggatatggt ttacaattat
    54481 gtagattaat cctgctgacg atggtttgtt aaaaaagagg agaaagtatt ggcaaaaaaa
    54541 ttaaaaaaga atgaagaaat cactaagaag tttggtgacg aacgtcgcaa agcccttgat
    54601 gatgctttga aaaatattga aaaagatttt ggtaagggcg cagtgatgcg attaggagaa
    54661 cgtgcagagc aaaaagttca ggttatgagt tcaggaagtc tagctcttga tattgcgctt
    54721 ggagctggtg gttatcctaa aggacgtatc atcgaaatct atggtccaga gtcttccggt
    54781 aaaacgactg tggctttaca tgctgtagca caagctcaaa aagaaggtgg aatcgcagcc
    54841 tttatcgatg ccgagcatgc gcttgatcca gcttatgctg ctgcgcttgg ggttaatatt
    54901 gatgaactcc tcttgtctca accagattct ggagaacaag gacttgaaat tgcaggtaaa
    54961 ttgattgatt ctggtgcggt tgatctggtt gttgtcgatt cagtagcagc tttagtgcca
    55021 cgtgctgaaa ttgatggtga tattggcgat agccatgtcg gattgcaagc acgtatgatg
    55081 agtcaggcca tgcgtaaatt atcagcttct attaataaaa caaaaactat cgctatcttt
    55141 attaaccaat tgcgtgaaaa agttggtgtg atgtttggaa atcctgaaac aacaccaggt
    55201 ggtcgagctt tgaaattcta tgcttctgtt cggctggatg tgcgtggaac aactcaaatt
    55261 aaaggaactg gtgaccaaaa ggatagcagc attggtaagg agaccaaaat caaggttgtt
    55321 aaaaacaagg tcgctccgcc atttaaggta gcagaagttg aaatcatgta tggggaaggt
    55381 atttctcgta caggggagct tgtgaaaatt gcttctgatt tggacattat ccaaaaagca
    55441 ggtgcttggt tctcttataa tggtgagaag attggccaag gttctgaaaa tgctaagcgt
    55501 tatttggccg aacatccaga attgtttgat gaaatcgacc gtaaagtacg tgttaaattt
    55561 ggtttgcttg aagaaagcga agaagaatct gctatggcag tagcatcaga agaaaccgat
    55621 gatcttgctt tagatttaga taatggtatt gaaattgaag attaaaaaga gcccttcagg
    55681 gctttttaaa atgtattttt aaaggttagt aggactactg ttcataggtg tgtgggtgaa
    55741 tagaaaccat catttaaaaa gatgtgagaa agcagaactt aggataactg atataaaatt
    55801 aaaataactg ataattcagg ggaatacagg tgaaagacct tattttacca agataatatc
    55861 tttaaaatta aaaaaatagg tccaaagacc tatatttata gataagaaac tgtgctacaa
    55921 taaagctatc acgaaataga aagtgagtca gcaacatgat taaaatttac acgatttcaa
    55981 gttgtacgag ctgcaagaaa gccaaaactt ggctaaatgc ccataagctt gcttataaag
    56041 aacagaactt aggaaaagaa ccgctaacta aagaagaaat tttagcaatt ttatcaaaaa
    56101 ccgaaaatgg agtggagagc attgtttcat ctaaaaaccg ttatgccaaa gctctcgatt
    56161 gcgatattga agaattaagt gttagtgagg ttattgattt gattcaagat aacccgcgca
    56221 tccttaaaag tcccattttg attgatgata aacgtctgca agtaggctac aaagaagacg
    56281 atattcgtgc ttttttacct cgctctattc gtaatattga aaatactgaa gcacgattac
    56341 gtgctgcgct ctaaaagctc ttgtagagct ttttttaaat accttcttcg cttgaaattc
    56401 ttgtttattt aatagaaata agctataata aagcatagca cttaatttta gaaagaaggt
    56461 gtaagtatgg gatttacaga tgaaacagtc cgctttaagt tggatgatgg cgacaaacga
    56521 caaattagtg aaacattaac agcagtctat cattcacttg atgaaaaagg ttataatcca
    56581 attaatcaaa ttgttggtta tgtcttgagt ggggacccag cttatgttcc tcgttataat
    56641 gatgctcgaa atcagattcg taaatatgaa cgtgatgaaa ttgtagaaga acttgttcgc
    56701 tactatttac aaggaaatgg aattgatgtt aaatgagaat aatgggactt gatgttggct
    56761 cgaaaacggt tggtgtagct attagtgatc ctcttggctt tacagcccaa ggacttgaaa
    56821 ttatcaagat tgatgaggaa aaagcagaat ttggctttac acgtttagaa gagcttgtta
    56881 agcagtacca agttgaacag tttgttattg gattgccaaa aaatatgaat aacaccaatg
    56941 gtccacgtgt tgatgcaagt ataacttatg gaaaccacat agagcacctt tttggacttc
    57001 cagtccatta tcaagatgaa cgattgacga ctgttgaggc agagcgtatg cttattgagc
    57061 aagctgacat tagtcgtggt aagcgaaaaa aagtcattga taaattagct gcacaactca
    57121 ttttacagaa ctatttaaat cggaattttt aaggagataa aaaatgacac ataatcatga
    57181 aaatgaccac caacacgaag ttatcacact tgtggatgaa caaggaaatg aaaccttgtt
    57241 tgaaatttta ttaacaattg atggtcgtga agagtttggt aaaaattatg ttctcttggt
    57301 tccagcggga tctgaagaag atgagtctgg tgaaattgaa atccaagcct attcgtttac
    57361 tgaaaatgaa gatggtactg aaggggattt acaaccgatt cctgaggatt cagatgctga
    57421 atgggatatg attgaagagg tatttaatag ttttctagat gagaactaaa ttgttagtga
    57481 cactatgtta aaaagtagcc gtgagggcta tttttttaat gttattttcg aataaataag
    57541 caggaggtga taatgataaa agaattaaat gataaattta ttaataatta taaggctaaa
    57601 cctttgcata gatttagaga attattacag tatgtgaaaa tatatcagaa attgactaaa
    57661 taaaagattc tgttatactt gttttataat attctttgac gataatatca tttttcaact
    57721 tactttgttt atgcacggtc actttgctat gtgcaataca aagtcatgtt atttaactca
    57781 tactaaaaaa taatggataa tagctatgtt agactagtga catgaagaaa tattgctttt
    57841 attgaatcgt tagagaatat gatatttcaa ggagaaaaat agtgatcgag ttaaacgatg
    57901 aattcatccg aaaagagacg atagaactgg ccaacgatgg cccacgagta cacaccactc
    57961 aatatgaaac taaagtacct cggcttcata aatgctatct gcttttcttt agcattatta
    58021 tcagttcttt aacaattgca gtaccttttt taacagatgc agccaatggt cttcagtccc
    58081 aaaacttata tataggaatg atgttaacga aggggcaagt tccctatagt gatactttta
    58141 caacaggagg gctcttttac tttgttatca ttgcattaag ttattatttg ggatcgacac
    58201 tttggctagt ctttgttcag gtgttttgtt tttacttatc tggtttatat ctttataaac
    58261 tcattaatta tatgacaggc tttcaaaaag tggctttaac tttttcaatt agctactatt
    58321 tgttgtctgt tagtcttggt tttgggggat tgtatcctac tcaactggct atgccattta
    58381 tattaatatc ggcttggttt ttaactaagt attttgcctg tttagtgaaa gatgaggcat
    58441 ttattctttt tggctttgta ggtgctcttg caatgctaat tgacccgagt acccttatct
    58501 tttggtcttt tgcttgtgtg acagtttttt cttataatat aagccaaaag catcttgcaa
    58561 gaggttttta tcaactgcta gcttcgattt ttggaatgat tttagttttt tacacagcag
    58621 gatatttcat tttgaactta caagtgctaa atccttattt atcacaaacg atgatttatc
    58681 cttttacttt ttttaaatca ggaaacttat cgttgctttt tggactggct attcagttgt
    58741 tcttcgcttt ggggcttggt cttttgacgg ggatggagaa tgtcattagg cgatttaaaa
    58801 acaattctga tagggtcgtc aagtggctat ttgtcatggt cattctagaa tctatacttg
    58861 tggctatatt ttcacaagac tatcgcccct atcatctttt acctctttta ccttttggat
    58921 taattttgac tgctattcct gttggctatc agtatggtat aggattaggt cagagtagtc
    58981 atcgcagacg tcatggtaaa aatggtgttg gtcgagtaat gatgatttat cttaagagac
    59041 acttttattt gccaatttta attgtaggga caatactaat ctgttctact tattgtttca
    59101 ttagtagtat tcctcttaat caggagcgtg atcatattgc tagttattta gaacagaaac
    59161 taaataaaac tcaatctatt tatgtttggg atgatacttc taaaatttat ttggacagta
    59221 aagctaaatc tgtttctcaa tttagttctc ctgacatcaa tacgcaaaaa gcgagtcatc
    59281 gaaaaatatt agaagatgaa ctattagaaa ataaggctgc ttatatcgtt gttaaccgct
    59341 ataaaaacct gcctaaaatc attcaaaaag tattatctac taattacaaa gtagataaac
    59401 agataacgac aaaaagtttt attgtttatc agaaaaagta atttaatatc aatatattgt
    59461 gttcgagcaa aaaacttgac acaatatatt gattttttta gttgtcgtga tataatagtt
    59521 ccgtaaggag atttgatatg gtaagtttag aagaagacaa ggtgactgtt caacctgata
    59581 ttaaagtgat taaacgagat ggtcgccttg ttaattttga tagtacaaaa atctatagtg
    59641 ctttattaaa agcaagcatg aaagtaactc ggatgtcgcc acttgttgag gctaaattag
    59701 aggctatttc tgatcgcatt atagcagaaa ttattgagcg ttttccaact aatatcaaaa
    59761 tttatgaaat ccaaaatatt gtagagcata agcttcttgc agctaatgaa tatgctattg
    59821 caaaagaata cattaattat cgtactcagc gtgactttgc acgttcacaa gcaacagata
    59881 tcaatttttc tattgataaa ttaattaata aagatcaaac agttgttaat gaaaatgcta
    59941 acaaagatag cgatgttttt aatactcaac gagatttaac tgctggaatc gtagggaaat
    60001 caattggttt aaaaatgtta ccttcgcatg ttgctaatgc tcatcaaaaa ggagatattc
    60061 attaccatga tttggattac agtccttata caccgatgac gaactgctgt ttaattgact
    60121 ttaagggcat gttagccaat ggctttaaaa ttggtaatgc tgaagtggaa agtcccaagt
    60181 ctattcaaac tgcaacagct cagatctcac agattattgc gaatgtagca tcaagtcagt
    60241 acggcggatg cacagctgat cgcattgacg agtttttagc cccatatgcg gagcttaact
    60301 ttaaaaaaca tatggctgat gctaagaaat ggatcgttga gactaagaga gaaagctatg
    60361 cttttgaaaa gactcaaaaa gatatttatg atgcgatgca gtctttggag tatgaaatta
    60421 atacgctctt tacgtctaat ggtcaaacac catttacttc tttaggattt ggtttgggga
    60481 cgtcttggtt tgaacgtgag attcaaaaag ctattttgac cattcggatt aatggtcttg
    60541 gtagtgaaca tcgcacggct attttcccta aattaatttt cacggttaaa cgtggcttga
    60601 atttagaacc agattcacca aactatgata ttaagacttt ggctttagaa tgtgcgacta
    60661 agcggatgta cccggatatg ttatcttatg ataaaattat tgatttgaca ggatctttca
    60721 aatctccaat gggatgccgc tctttccttc aaggctggaa agatgaaaat gggcaagatg
    60781 tgacctcagg ccgtatgaat cttggggttg tcaccctcaa tttacctcgc attgccatgg
    60841 aatcaaatgg cgatatggat aagttttggg agctgtttaa tgagaggatg ctaattagta
    60901 aggatgcttt aatttatcgt gtcgaacgtg tcacagaagc aaaaccagca aatgccccta
    60961 ttctttatca atatggtgct tttggaaagc gtttggagaa gacagggaat gtaaatgatc
    61021 tctttaagaa tcgtcgtgca acagtctctc ttggctatat tggtctttat gaagtggcat
    61081 ctgtttttta tggtggtcaa tgggaaggta atccagatgc taaagctttt accttgtcaa
    61141 ttgtcaaggc aatgaaacag gcctgtgagg attggtcaga tgaatatggt tatcatttct
    61201 ctgtttattc gactccatca gaaagcttga cagatcgctt ttgtcgttta gatacggaaa
    61261 aatttggcat tgtgacagat attacggata aagaatacta tacaaattct tttcactatg
    61321 atgtgcgtaa gagtccgaca ccttttgaaa aattagattt tgaaaaagat tatccagaag
    61381 caggtgcttc aggtggtttt atccactact gtgagtatcc tgttttgcaa caaaatccaa
    61441 aggccttgga agcggtttgg gactatgctt atgatcgtgt ggggtatttg ggaaccaata
    61501 cgcctattga taaatgctat aattgccaat ttgaaggcga ttttacccca acagaacgtg
    61561 gttttacttg cccaaactgt ggcaataatg accctaaaac agttgatgtg gtcaaacgta
    61621 catgtggtta cttggggaat cctcaggccc gcccaatggt taacggtcgc cataaggaaa
    61681 tctctgcgcg tgtaaaacat atgaatggtt ctactataaa atacccaggc ctgtaaactc
    61741 aagctggggg agagcccttt tgatggaaat atgatatgct taaaaggttg cttcatgcaa
    61801 gcaatctttt attgtttaat ggtttcttag caattgtgag ataagaataa ctaatccaaa
    61861 acgactaatt agctgttagc aatcggacta taagaagaaa gagataagga agaaataatg
    61921 ggaaaatatc aattagacta taaaggaatg cagcaggtag aacgctttca tgagaagcat
    61981 tctaaaaaaa agacggataa aaaatcccgc gttcaagaac ttaaggctcg gtttttagag
    62041 aagtcaaaaa aacaggataa ctaaagtatc caataaagaa agaaggttga gtatgcttaa
    62101 tattgggatt gtgggactag gtgccatttc acaaaaagcc tatttaccat atatgagaca
    62161 gctgagtgac attacttggc atctatcaac gcggaatgca gcagtacgtc agcaggtcgg
    62221 tcagttattt ggtcacgcta ttctttacag tgatgtcaag gagttgtcaa aggcaagttt
    62281 agatggcgtc tttattcatg cggccacatc ggcccacgca gagttggcta gtttattttt
    62341 aaatcagggg atcccagtct ttatggataa acctatagct gacaattacc tgatgacaaa
    62401 gaacctctat gacttagcca aagaaaatca gacttttctg atggcaggat ttaacaggcg
    62461 ttttacacct cgtgtcaaga agttgtcaag tttgtcaact aagcgtaaag tggctgttga
    62521 aaaaaatgac ttgaaccggc caggagatat gacttttaag ctctttgatt tctttatcca
    62581 tcctttagat acagccttat tcttgtcaga agggacctta ctaaaagggc attttcaata
    62641 tcatctggaa gcaggcttac tgagtcaagt tatggtaacc ttgatgaccg aaagcatgac
    62701 gactacagct tctatgaatt tacaatcagg gagtcgccgt gaggtaatgg aagttcaacg
    62761 ggctgaagaa acttatcatt tagagaactt agacgagtta tctatttata aaggtactga
    62821 aaaaagggtg cttggctttg cttcttggga cactaccttg cacaaaagag gttttgaaac
    62881 aatgatcgat gcctttttag aagctattag cacaggcgtc aatcctgtca gtcctgagtc
    62941 tagtctttta agccactgga tttgtcaaca gattgctgac tctcagcttt cttatggaga
    63001 gttaacggta gagttgccta aggattagga attgatatgg aaacaagacg accgacttta
    63061 aaagataaag atgctgtatt gtcaatgatt aacgaatttt tagagcagaa aagtgctaca
    63121 gatgggttat ggcattttaa cgtcaatgac ttcaactatg aaacatggtt ggaagattcc
    63181 ttgcgacagg aaatgggttt ggccagtcaa ggagtgcctg ctattcaata tgtggcgttt
    63241 gatgagaaaa atcaagcttt gggattttta aaccttaggt tacgtttaaa tgcctcatta
    63301 cttgaaaaag gtgggcatat tggttactct gtccgtccca gccagcgtgg gaaaggttat
    63361 gccaaggaga tgcttaaaca agctgtcagc tgtgcgattt ccaagaatat cacgacaatt
    63421 ttggtaactt gtgatgagac taatgttgca agccgagcag ttattgtggc taacggtggt
    63481 gtcttggaag atagtcgagg tggaacggaa cgttattgga ttgaagaaca aagaggcgat
    63541 aagtgatggc agaaaagtgt tggaataatc ctaagccaaa ggaatggcag gcagaggagt
    63601 taagtcaagg ccggattatt gactataagg cttttaactt tgttgatggt gaaggggttc
    63661 gtaattccct ttatgtgtct ggttgtttat tccattgcaa ggggtgttat aatgctgcga
    63721 cttggtcttt taaggcggga atgccttata cgcaagaact tgaagagcag ataatgacag
    63781 atttggcaca gccttatgtt cagggactga cacttttagg tggagaaccc tttttgaata
    63841 cgggtatctt aattcctctg attaagcgta ttcggcgtga attgccagaa aaagatattt
    63901 ggtcttggac gggttatact tgggaagaaa tgatgcttga aacaccagac aaactggaaa
    63961 tgttgtcctt aattgatatt ctggtagatg gtcgttttga tatcacaaaa aagaacctca
    64021 tgttgcaatt tagaggttct tctaaccagc gaattatcga tgttcaaaag tctttggctg
    64081 ctaaagaagt gattatctgg gataagttaa acgatgggga ccaaaccttt gaacaaatta
    64141 gtcgggagga tttgctttaa gaagctgact tatccacatg atttttttga aaaggtcatg
    64201 tgaaaacagg tcctttaagg gtgaattggg gagaaagtga ttgttatttc ctggttttcc
    64261 ccacattatc ctcatagtta tccacaggat gtgtataagt tgtagaattg tgaataaaga
    64321 ctaaaaaaga ggcctaggcc tcttttttga tatagacaaa ttcataatct gttgataggt
    64381 ctggatggta gtaaaaacca gcaaagacaa ggcttttaag gctgtcaaca gtttggcaat
    64441 tattttccat acaggcagtg agaaatgcac ctcgtgcctt ttttgaaatg gtggaatggg
    64501 ttttgaattg gccctctttt tctgccataa acttgggact tatccacaat tgtttacagt
    64561 ctttggaaaa gacatcgtca aattcactgg ataaaaggga aatcacttgg ggatgctctt
    64621 tggcaaactg attataacag ggccgccagt aagacttgag gctttgtcct tcaattttta
    64681 ttctggtgtg aaaatcatgg cggtgctctg cgataggatg attagcggga atgataccgt
    64741 aaaaggatga ggtgatgtaa acctgctggg tgatgtaagc ctgttcttga gtagtgagct
    64801 tatcgcgctt gatatggcgg tacataaggc cattgaacag ttggtaggca gggtaagcca
    64861 agctttgttg agaggccatg tcttgccagc gttgctgttc ttttttagct gcctcttctt
    64921 tgatacgata tgatttggcc aagtcctccg tggtcatagc tgtcatgatt tttaaaatgg
    64981 cttggctgtc ttgtggaagg aggtgtgggt gagattcctt aggggtcgtc atttcttttg
    65041 cggttggaat taaaaaggtt agcatagtgt tattgtagta aagttacttg ctttctgtca
    65101 agaaaactag tcttgtccaa ggatgacgtt caaacggcta ccttcctcgt cttctgtcgt
    65161 gaaagaagaa gaatcttctt gtaaaatagc taggccatat catctggctt ttttgagagt
    65221 ggctgaaaaa agcaggggcg tctcaatgtg aatggttaag aaggctagac ctggagtgcc
    65281 ttcttggtgt tttttgaggt aaggtccaga ccattgattg aatgcaaggt ggtgatggta
    65341 gttccctgaa gcaatccagc tagcacttgg aatagtcatt ttatcgccta aatcaaaaac
    65401 cttttgatag agaagtgaag aatccagagc atttttgaca ctcagatgga catgactgat
    65461 gcgtgtgtct tgagctagta aaaagtgctt ggggatatct gtcaactgct ccaatatgct
    65521 tttggtatcc gtgggctcag tcacaccaat aatttgacca ttgtcgcgga tatcccaatg
    65581 ctcaacagct ttgtcatgat agatttcaat cccattaccc tcaggatcgc tgaggtagat
    65641 agcttcgcta tagccgtgat cagctgctcc ttctaaagag atacctctgg ttaagaaatg
    65701 aagtcccaag ctatgacgat caggaactaa aaaggctgtg tgataaagac cataagcctt
    65761 atttgctggt aaaggtgttt gtcgtaactc taagataacg gttttaccgt ctgtagtcaa
    65821 ttgacgagat gtcgtgtctt gtgagagaac ctgtaaaccg ataatacttg tgtaaaaggt
    65881 tgtcatcttt gctagatcgg taacattgag ggaaaccttt cctagagaga tggttgagtt
    65941 gtaagggtat gtcatcctat tgtctccaaa agtgattaag cctatgataa cttattagtt
    66001 tcaaaaagaa aagtaggcac aaataagtgg tataggcact aaaaagtaac tcatttgtca
    66061 gccctatctt gtttctgttc tctctaatag tctataatgg gttataagtt acaaaaagat
    66121 actaagagga gctgctgcct atgctgaaaa aaagaccggc ttgtcccgta gaaacaacct
    66181 tatcggtaat caggaataaa tggaaattat taatattaag ggacttgcta aaggggacct
    66241 tgcgttttgg gcagttgaag tcctcaatag gttcggtcag tcaaaaggta cttactgccc
    66301 aattaagggc tatggaagct catcgggaag tgtatgcaga agtgccacct cgggtagagt
    66361 attccttaac agaaactggg ttgagcttag ctcctgttat tgaagcgatg tcggattggg
    66421 accaaactta ccaagaaaaa catgccgatt tatttgaaga aggctagagg aaagagttgt
    66481 ccgagcatac tgagacttag agaagctgag agttttttta aaatgatatt atcaaattct
    66541 ttacagtttg ataaaattac tttttttcta caaaaagact tgcgctcatc tcacgaatat
    66601 gataatataa tatcaagtct gtttgagaaa acagaagctc aggtcaagta agtgcacact
    66661 tacaataaca cagttgataa tggggaaact cagagtcaag aaaaagaaaa gcaagccttg
    66721 cattttgcaa ggcttttttc tgtctttatt ttggtctgcg ccgagcaaaa tctaaaaatt
    66781 taaatttttc cagtttatgg cgactctcgg tgaattggaa ttggttatta ttggaaaggt
    66841 aaactttgga tttgacggaa acaacatgtt ggtctgatcc aaggtcaagt aaaattttat
    66901 cacgatcggt tatttggtca atggtaacct ctttgagggc aaagtcaatg gcgagatgga
    66961 gttccttttc caaatattga taaatagaat gctctgcgat ttcccttgtc attattggca
    67021 ccaaagtttt actaaggtaa tcaatgtcta agacggaagc cacaccctca acaacgcgtt
    67081 ggcgcgtaac acgccagacc aagctgtttt tgctaaaacc ggtcaatttt gaaagtgtct
    67141 catccacaat cagtttatca atggcaatga cgttggtctt agaatctaga tttgagtaag
    67201 agacgagttc ctgataacta gttagttctg agatagggaa catgatctga tgatgtttaa
    67261 tcacttgggt gccacgtcct tgttttttga ggataagacc tgcctttgtg agaagtgaga
    67321 gagccttgcg gacggtatct cggctagctt ggtattgttg actcaattct atttcagtag
    67381 gtaaaaaatc cccttctttg taaaagtctt tgtttatttt tgtttcgagg tctttataaa
    67441 tacgttcata ctttgtcata gggtaaatta cctttccact tgtctatttt tttacagaca
    67501 acacctttta ttttaccaaa ataatggctt ttttggcaca aacaacttgc agacaaattt
    67561 gcaatcgatt acaataaagg tgtcaatcat attttatcta agaatttgaa tatttcattt
    67621 tgacgttgct tgttaaaagc aactagaaca aaggactagg ggatgtcaca tgggaaaatt
    67681 tgaacaggat gctaaaagtc ttctaactgc tattggcggt aaagaaaaca tcaaggctgt
    67741 cacacactgt gcaacgcgta tgcgttttgt tttgaatgat aataataagg caaatgtcaa
    67801 agagattgaa aaaatctctg tagttaaagg gacatttacc aatgctgggc agtttcaggt
    67861 aatcattggt aatgatgttc cagtttttta taatgacttt acagctgttt ctggtattga
    67921 aggggtgtct aaagaagctg ccaaatcagc agctaaaagt aatcaaaatg ccttacaacg
    67981 ggtgatgacc atgttggctg agattttcac acctattatt ccggcgatta ttgttggggg
    68041 gcttatttta ggtttccgta atattttgga gagtgtgcct tttgaatttc ttgggcagca
    68101 ggtcgaaaaa gggaaattag tttttgatgc agctggggat cctgtttgga atacgattgt
    68161 gagggtatct cctttctggt caggggttaa ccatttcttg tggttaccag gggaagctat
    68221 tttccacttc ttaccagttg ggattacttg gtctgtgacg cgtaagatgg gaaccactca
    68281 aattttaggg attgtccttg gtatctgttt ggtgtcacca caattattga atgcctatgc
    68341 ggtagcagga acgcctgctg ctgagattgc caaaaactgg gtttgggatt ttggtttctt
    68401 taccattaat cgtattgggt atcaggcaca ggttattcca gcccttttag ctggtctgtc
    68461 ccttgcttat cttgaaattt tctggcgtaa acggattcca gaagtggttt caatgatttt
    68521 tgtgccattc ctttctttga ttccagcttt gattttagcg catacggtat tggggccaat
    68581 cggttggatt attggtaaag ggatttcctt tgttgtgtta gctggattga ctggtcctgt
    68641 taaatggcta ttcggtgcta tctttggtgc cttgtatgct ccgctagtta ttactggttt
    68701 acatcacatg acaaatgcca ttgataccca attaattgct gatactgcaa ctcgtacaac
    68761 tggtttgtgg ccaatgattg ctctttcaaa tatcgctcaa gggtcagctg tttttgctta
    68821 ctatttaatg aatcgtcatg aagaacgtga ggctgaaata tcgcttcctg cagcaatttc
    68881 tgcttacctt ggggtaactg agcctgcctt atttggggtt aatgttaaat acgtttatcc
    68941 ctttgtagcc ggaatgattg gctcaggtat tgcgggtctc ttatcaacaa cctttaatgt
    69001 tcaggcaaat tctattggtg ttggtggctt accaggtttc atggctatca atgtgaagta
    69061 tatgattcca ttcttcatct gtatggcagt agccattgtg gtatcgatgt ttttaacctt
    69121 ctttttccgt aaatcacata tcatgactaa gacagaagat gaggctaaac tacctgagac
    69181 acccgtttcg gaggctcctg cagcaactgc tccacataag actatgcaag gaacagttat
    69241 cactttaacg agccctttaa ctggtgaagt taaagcgttg tctgaagctg ttgatcctgt
    69301 ctttgcacag ggaattatgg gccaaggtgc tcttcttcaa ccgacagaag gggtgttagt
    69361 agcgccttgt gatgctgaag tatcggtctt gttcccaacc aaacacgcta tttgtttggt
    69421 gacgactgaa ggtttggaat tattgatgca tattggcatg gatacggtta acttagatgg
    69481 tcaaggattt gaagctttgg tgaagcaagg tgatcaggtt aaggctggac aaacattgat
    69541 tcaatttgat atagcagcta tttctgaagc tggatacgcc actgaaacgc ctcttgtggt
    69601 gactaatcaa gatgctttta cggtaactgt tgaaggtagt ttaccgcatc agattaaggc
    69661 taatgataag ttagcagtag cggtgaaaaa gtaggtttac taagagaaaa cgttcaggaa
    69721 ctgagatcag ttcctgaaac tattttaggg aggaaaactc atgacaattg ataaaaagaa
    69781 agtcgtctat caaatttacc caaaatccta taaggacact actggaaatg gtgtgggaga
    69841 cttgcgaggg atcattgcta aattgcctta cttacaagaa ctaggaatag atatgatttg
    69901 gttgaaccct ttctacccta gtccacaacg agacaatggc tatgatgttt cagattatac
    69961 ggcggtcaac cctgattttg ggactatggc tgattttgaa gatttggtaa aagctgctaa
    70021 ggagcatcag attgagttaa tgttggacat ggttttgaat cactgttcca cagaccacga
    70081 gtggttccaa aaagctttag caggagaccc ttattatcag gatttcttta tcttgagaga
    70141 tcagccgact gattgggttt ccaaatttgg tgggaatgct tgggcgcctt ttggagatac
    70201 aggcaagtac tacttacact tgtttgatgt gacacaggct gacttgaatt ggcggaaccc
    70261 acatgttcgt gaggaattgg ctaaagtggt taatttttgg cgagataaag gagtgaaggg
    70321 gttccggttt gatgtgatta atctgattgg gaaagatgaa gagctggtgg attgtccagt
    70381 caatgatggt aagccagctt atacggatcg tcctattact cacacttatc ttcatgatct
    70441 caatcaagcc agttttggtc aggatgattc gtttatgaca gtaggggaaa tgtctgccac
    70501 gactattgac aactgtcttt tatacacggc tcccgaacgt gaggagctat ccatggcttt
    70561 taatttccac catctaaaag ttgattatga gaacggtcag aaatggacta ttatggcttt
    70621 tgattttgca gcgctgcgag acttattcca tgcttggggt gaaggcatga gtcaaggcaa
    70681 tgggtggaat gccttgttct acaataacca tgatcaacca cgtgccctga atcgttttgt
    70741 tgatgtaaca catttccgaa acgaaggtgc gacgatgtta gcggcttcca tccatttgtc
    70801 acgaggaacg ccttacattt atatgggtga ggagattggc atgcttgatc cagactttga
    70861 tagtatggat gattatgtgg atgtggaaag tctcaatgct tactcaagct tactagtctc
    70921 aggtaaaagt gcagaagaag cctttgccat tatcaaggat aagtcaaggg acaatgccag
    70981 aacaccaatg caatgggatg ctagtgaaca tgctggcttt acgactggta agccttggtt
    71041 agaggttagc aaatcttatc gagacatcaa tgtcgaaaca gaaaaagagg gacgtatttt
    71101 tcctttctac caacgcttga ttgctttgcg gaaggaactc cctattattg ctgaagggga
    71161 ttatcgggct gcttttaaag atagtcagtc tgtctacgcc tttgaacgcc atttaggtga
    71221 ccagtgtttg cttgttctca atcatttcta tgctgatgag gtcgaactgg aattacctcc
    71281 acgttatcaa catggacagg tcttaatcag caactatgag aaagtttcta tttgtgaaaa
    71341 agtgatactg aaaccttatc agacacttgc tatcttagct gaaaactaac taaaagcctg
    71401 aggttaggcc tcaggctttt ggtgattgtc acgaaaaaag aagttttctc atatatttat
    71461 ttttaaactc ttattttttc taaataaaaa caattgagat aagttatttt agctaaattt
    71521 tggtacaatg gaaaagatta taagtagagt ttaagataaa gattctacaa atttaaaatg
    71581 atataaggag atacgaatga caacttatca agatgatttt taccaggctg tgaatggaaa
    71641 gtgggctgaa acagcagtta ttccagacga caagcctcga acaggtggat tttcagactt
    71701 agcagatgaa attgaggcat taatgctaga cactacagat gcttggctag ctggagaaaa
    71761 tatccctgat gatgctattt taaaaaattt tgtgaaattc catcgtttgg tggctgacta
    71821 cgctaaacgt gatgaagttg gagtaagtcc aattctccct ttaattgaag aatatcagtc
    71881 cttaaaatct ttttcagaat ttgttgctaa tatagcgaaa tatgaattgg caggtttacc
    71941 aaatgaattt ccctttagtg tggcaccaga ctttatgaat gctcagctga atgtgctttg
    72001 ggcagaagca ccaagcattc ttttgccaga tacaacatac tacgaagaag acaacgaaaa
    72061 agctgaggaa ttgcgtggta tttggcgtca gtcgcaagaa aagcttttac ctcaatttgg
    72121 tttttcaaca gaagaaatca aggatctttt ggataaggta attgagctag ataagcaatt
    72181 ggccaagtat gtcttgtctc gtgaggaagg ctcagaatat gccaaattat accatcctta
    72241 tgtgtgggct gattttaaaa aactagctcc agagcttcct ttggatagca tttttgaaaa
    72301 gattttaggc caagtacctg acaaggttat tgttcctgag gaacgttttt ggacagaatt
    72361 tgcagccact tattactctg aagccaattg ggatttactc aaggctaatt tgattgtgga
    72421 cgcggctaat gcttacaatg cttacttgac ggatgatatt cgtgtggaat caggcgctta
    72481 ttcgcgcgct ctttcaggaa cacctcaagc tatggacaaa caaaaagcag ccttttattt
    72541 ggcgcaagga ccgtttagcc aagcgcttgg cttgtggtat gctggtcaaa aattctcccc
    72601 agaagctaag gctgatgtgg aaagcaaggt agcacgcatg attgaggttt ataagtctcg
    72661 tctagaaacg gctgattggt tagcaccagc cacacgtgaa aaagccatta ctaaattaaa
    72721 tgttatcacg ccacatattg gttacccaga aaaattacca gaaacctatg ctaaaaaagt
    72781 gattgatgag agcttgtcat tggttgaaaa tgcacagaac ttggctaaaa tcacgattgc
    72841 tcacacttgg agtaaatgga acaagccagt tgaccgtagt gaatggcata tgccagccca
    72901 cttagtcaat gcttattatg atcctcagca aaatcagatt gtctttcctg cggcaatctt
    72961 acaagagcca ttttattctt tagatcagag ttcttcagct aattatggag gaattggtgc
    73021 agtcattgcg catgagattt cacatgcctt tgacaccaat ggtgcttcct ttgatgaaca
    73081 tggtagccta aatgattggt ggacacaaga agactatgct gcctttaaag agcgtacaga
    73141 taagattgtg gcgcagtttg acggcttaga gtcacatggt gctaaggtca atggtaaatt
    73201 gacagtttca gaaaacgtcg ctgatctagg tggggtagct tgtgctttag aagcggcaca
    73261 atcagaagaa gacttctcag cccgtgactt ctttattaac tttgcgacga tttggcgtat
    73321 gaaggcccgt gaggaataca tgcaaatgct agctagcatt gatgttcatg ccccgggtga
    73381 actgcgaaca aatgtcacct taaccaactt tgatgctttc catgagacct ttgatattaa
    73441 agaaggcgat gctatgtgga gagctccgaa agaccgtgtg attatttggt aattaggtag
    73501 ttgataaacc ttcaaatgct tgtgattata aaaatgactg attctgtgaa acacaggatc
    73561 agttttttgc ttccttattg gtgtccgttt tgacacaaca aaaagacaac cctcaggaaa
    73621 gaaggttgcc ttttttagac ttatcagaaa taagtgatta gttgttaagg gcagcagcca
    73681 tagtagctgc aacttctgat tcaaagtcgt tagctttttt ctcgatacct tcaccaactt
    73741 caaaacgtgc aaaagcaatc gctttagcgt ttactgagtc aaggtaagct tcaacagttt
    73801 tgctgtcgtc catgatgtaa acttgtgcaa gaagagtgta agcttggtca actttagtgt
    73861 tgtcaagcat gaagcggtcc attttacctg ggatgatttt gtcccagatt ttttctggtt
    73921 tgccttcagc agcaagttca gctttgatgt ctgcttcagc agcagtaatc acatcgtctg
    73981 ataattgagc ttttgaaccg tatttcaaga atggaagtgc tggtttgtca accattgcac
    74041 gcgattcgtt gtcaagttcg atagcgtggt tcaattgagc aagttcatct ttgatgaatt
    74101 gtgcatcaag ctcagtgtat gaaagaacag ttggtttcat tgcagcgata tgcattgata
    74161 cttgtttagc aagagcatcg tcgccgcctt cgacaactga gataaccccg atacggccac
    74221 cattatgttg gtaagcaccg aagtgttgct catctgtttt ttcaatcaaa gcaaaacgac
    74281 ggaatgagat tttttctccg atggtagcag ttgcattaac gtaagcttca gcaagagttt
    74341 cacctgaagg cataacaagt gcaagtgctt catcgttgtt agctggtttg ccttcagcga
    74401 taactttagc agttgcgttt accaattcaa cgaattgagc atttttagca acaaagtctg
    74461 tttcagcgtt aacttcaaca acagcagcaa cgttaccatg aacgtaaacg cctgttaaac
    74521 cttcagcggc aacacggtca gcttttttag ctgctttagc cattcctttt tcacgaagaa
    74581 gttcaacggc tttgtccatg tcaccatctg tttcaacaag tgctttttta gcgtccataa
    74641 cgccagcacc agatttttca cgtaattctt ttacaagctt agctgtaatt tctgccatgt
    74701 gtagtatcct ccaaatgata tttgttttgg tttcaaaaaa cgagacagag cggtttgctt
    74761 tctgccccgt ttggttttcg attgttaaag acaaacgaag tttgccataa gagttaggaa
    74821 ctctgtgcta attaagcgtt gtcgccttcg acaacttcaa cgatgtcttc gattgaatct
    74881 gcttgagtgt cagcttcaaa agcaacgtct gcatcttcac cttgacggcc ttcgataata
    74941 gcgtcagcta atttagcagt aattaattta acggcgcgga tagcgtcatc gttagctgga
    75001 atgatgatat cgatatcatc tggatcagcg tttgtatcaa ccatcgctac gactgggata
    75061 ccaagttttt tagcttcttt aacagcaatt tgttctttat gtgggtcaac aacatacatc
    75121 acgtctggga tacgaggcat atcttcgata ccgcccaaga atttttcaag acgagcgcgt
    75181 tgtttgttaa gaagtgcaac ttctttctta ggaagaacgt caaaggttcc ttcttcttcc
    75241 atacgtttga tttctttcaa acgagcgata cgtttttgga tagttcccca gttggtaagc
    75301 gttccaccca accaacggtg gttgatgaag tattggcctg cacgcgttgc ttcgtcagca
    75361 actgcttcag cagcttgttt tttagtacca acgaacaaga tgacagcatc gtttgctgca
    75421 gcatcacgaa caaattcgta agcttggtca gctaatttta cagtttgttg aagatcgata
    75481 acgtggatac cgttacgctc tgtgaagatg tatttagcca tcttagggtt ccagcgacga
    75541 gtttggtgac caaagtgaac accagcctca agaagttgtt tcattgaaat tactgccatg
    75601 agtagtttct cctttataaa atgttttttc ctcttccaga cttcgacttg caggctaacc
    75661 tagcggcaac aagcccacaa ttggtctaga atgagtattt gccgtctaca cgaccctact
    75721 atattatcaa aaaaagaggt taaaagcaag gagaaatgct atgaattccc ttattttcga
    75781 gatgactagc ttctttgttt attg
//
LOCUS       DAXMQE010000005        66305 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.005, whole genome shotgun sequence.
ACCESSION   DAXMQE010000005 DAXMQE010000000
VERSION     DAXMQE010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 66305)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 66305)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..66305
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.005"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            <1..1422
                     /gene="glyS"
                     /locus_tag="ACF4ZO_000356"
     CDS             <1..1422
                     /gene="glyS"
                     /locus_tag="ACF4ZO_000356"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HFD5485935.1"
                     /translation="RSQFVIADAKERQEMIVEQIKTLEVEQGVQVDIDEDLLNEVLNL
                     VEFPTAFMGSFEAKYLDVPEEVLVTSMKNHQRYFVVRDQEGRLMPNFVSVRNGNDQAI
                     ENVIKGNEKVLVARLEDGEFFWREDQKLQIADLVAKLTNVTFHEKIGSLAEHMDRTRV
                     IAASLAKEANLSAEEEAAVDRAAQIYKFDLLTGMVGEFDELQGIMGEKYALLSGEDAA
                     VATAIREHYLPDAAGGALPETKVGAVLALADKLDTLLSFFSVGLIPSGSNDPYALRRA
                     TQGIVRILDHFGWRIPMDKLVDSLYDLSFDSLAYTNKADVMNFIRARVDKMMGKAAPK
                     DIREAILASSTFVVPEMLAVAEALVKASHTENYKPAVESLSRAFNLAEKADASVHVDP
                     SLFENEQENTLFAAIQGLTLAGSAAQQLEQVFVLSPVINDFFDNTMVMAEDQALKNNR
                     LAILSDLVSKAKTIAAFNQLNTK"
     gene            1576..1833
                     /locus_tag="ACF4ZO_000357"
     CDS             1576..1833
                     /locus_tag="ACF4ZO_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HFD5485936.1"
                     /translation="MDPKKIARINELAKKKKTVGLTGPEKVEQAKLREEYIEGYRRSV
                     RHHIEGIKLVDEEGNDVTPEKLRQVQREKGLHGRSLDDPKS"
     gene            1960..2352
                     /locus_tag="ACF4ZO_000358"
     CDS             1960..2352
                     /locus_tag="ACF4ZO_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HFD5485937.1"
                     /translation="MCLSYNRRNQRKKVVLMTIKKFSLLAIASLSLLSLAACDMDDKD
                     DHMDNQPKTSQTSKKVKLSEDKAKSIALKDASVTEADAQMLSVTQDNEDGKAVYEIEF
                     QNKDQEYSYTIDANSGDIVEKSSEPIND"
     gene            2712..4226
                     /gene="glpK"
                     /locus_tag="ACF4ZO_000359"
     CDS             2712..4226
                     /gene="glpK"
                     /locus_tag="ACF4ZO_000359"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004370 - glycerol kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HFD5485938.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNQKGEKVSSSQKEFPQIFPHAG
                     WVEHNANQIWNSVQSVIAGAFIESSIKPSQIEAIGITNQRETTVVWDKKTGVPIYNAI
                     VWQSRQTAPIAEQLKQDGHTKMIHEKTGLVIDAYFSATKIRWILDHVPGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAVHVTDYSNAARTMLYNIKDLTWDDEILELLNIPKDMLPEV
                     KSNSEIYGKTAAFHFYGGEVPISGMAGDQQAALFGQLAFDPGMVKNTYGTGSFIIMNT
                     GDEMQLSSNNLLTTIGYGINGKVHYALEGSIFIAGSAIQWLRDGLKMIETSPESEQFA
                     LASTSDDEVYVVPAFTGLGAPYWDSNARGSVFGLTRGTSKEDFVKATLQSIAYQVRDV
                     IDTMQVDSGIDIQQLRVDGGAAMNNMLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     AVGYWEDMDALKELNATGQLFKASMNESRKEKLYKGWKRAVKATQVFTQDDDAE"
     gene            4242..6080
                     /gene="glpO"
                     /locus_tag="ACF4ZO_000360"
     CDS             4242..6080
                     /gene="glpO"
                     /locus_tag="ACF4ZO_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004368 - glycerol-3-phosphate
                     dehydrogenase (quinone) activity [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HFD5485939.1"
                     /translation="MEFSKETRRLALQKMQERDLDLLIIGGGITGAGVALQAAASGLD
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKPDP
                     MLLPVYDEPGSTFSMFRLKVAMDLYDLLAGVSNTPAANKVLTKEEVLKREPDLKQEGL
                     LGGGVYLDFRNNDARLVIENIKRANRDGALIASHVKAEDFLLDDKRQIIGVKARDLLT
                     DQEIIIKAKLVINTTGPWSDEIRQFSHKGQPIHQMRPTKGVHLVVDRQKLPVSQPVYV
                     DTGLNDGRMVFVLPREEKTYFGTTDTDYTGDLQHPQVTQEDVDYLLGIVNNRFPNANL
                     TINDIESSWAGLRPLLSGNSASDYNGGNSGKLSDDSFDHLIDTVKAYINHEDSREAVE
                     KAIKQVETSTSEKELDPSAVSRGSSFERDENGLFTLAGGKITDYRKMAEGALKVIIQV
                     LKEDFGKSFKLINSTTYPVSGGEINPANVDSELEAYAQLGTLSGLSMDDARYLANLYG
                     SNAPKVFALTRQLKAAEGLSLAETLSLHYAMDYEMALKPTDYFLRRTNHLLFMRDSLD
                     ALIVPVIEEMAKHFDWSTDEKVKQEEELRRVIAENDLSALKGQQED"
     gene            6082..6783
                     /locus_tag="ACF4ZO_000361"
     CDS             6082..6783
                     /locus_tag="ACF4ZO_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MIP/aquaporin family protein"
                     /protein_id="HFD5485940.1"
                     /translation="MDIFGEFLGTALLVLLGNGVVAGVVLPKTKTHASGWIVIATGWG
                     IAVAVAVFISGKIAPAHLNPAVSLAFAMSGTIAWSTAIAYSLAQLLGAMLGSTLVFLQ
                     FRPHYLAAESQADILGTFATGPAIRDTSSNLLSEIFGTFVLMLGILAFGLYDMPAGLG
                     TLCVGTLVIGIGLSLGGTTGYAINPARDLGPRLVHAILPLNNKGDSDWSYAWIPVVGP
                     IIGAALAVLLFQVMS"
     gene            6892..8238
                     /locus_tag="ACF4ZO_000362"
     CDS             6892..8238
                     /locus_tag="ACF4ZO_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFD5485941.1"
                     /translation="MTLTTKTIHVIGASFAGLAFVDKYKDLNPDSQIILIDKESCPNY
                     IPNGINQLFRGDIQDLSDAMWGRACLAAQIESNHRFIQAEVLAIEAPSNTLLLKDSQG
                     RVFEEGYETLVCAMGASPQSHYIETSQTNKVLVTKYYEESQASLKLIEASQEVLVIGA
                     GLIGLDLAYSLSLQGKRVKLIEAAERPDFYQTDAELIAPVMAEMSTHHVTFINNKRVT
                     AIHEIEGKVVAHTEQGDTFQGDLAILAINFRPNTHLLQGQVACALDKTILVNENLQTS
                     QANIYAIGDMVSLHFGILGMDYYTPLINQAMKTGQALALHLAGYPIPPLQTVKVLGSS
                     HFGYYRASVGVTEEEAELYMDTCSYLYQNGDSKNLFWLKLIARKTDGILIGAQLLSKT
                     NALVIANQLGQALALKVTDADLAFQDFLFLQGHSDLAYHLHEACLKLFEKRLRHED"
     gene            8228..9727
                     /locus_tag="ACF4ZO_000363"
     CDS             8228..9727
                     /locus_tag="ACF4ZO_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD5485942.1"
                     /translation="MKIEDLMDKERRAQYRLLVTLYHAKETLRLKDLMRLSNLSKVTL
                     LKYIDNLNHLCREQGLACQLLLEKDSLSLKENGQFHWEDLVALLLKESVAYQILTYMY
                     CHEHFNITNLSVELMVSEATLNRQLAHLNQLLSEFDLALSQGRQLGSELQWRYFYFEL
                     FRHTLTRQGRDALVNQLDASHLATLIERLIGQSLSAEALEQLLIWLAISQARMSFQKG
                     YNDHFLRDSDFMTSNIFFKRLESMLLRYLRRYALEFDAFEAKSLFVFLHAYPLLPIAS
                     MKYSLGFGGPIADHISEALWLLKKAHVIIHQTKEEIIYGLGIFFSKAYFFKGAILSQP
                     TNSQYLYQLVGEDKRALLRVIINHLVLQMDQETDFSQQLSDDILALLIFSIERHHEPL
                     LVGLALGQNKVEAAIAELAIRRHLGHRRDFQLMPYDHQKVYDCLITYQTVCLPRQDLP
                     YYRLKQYSSPYELTALEAFLKDLFQQKNTREEELSLSPAAKSSFAHKIV"
     gene            9853..10497
                     /gene="fsa"
                     /locus_tag="ACF4ZO_000364"
     CDS             9853..10497
                     /gene="fsa"
                     /locus_tag="ACF4ZO_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HFD5485943.1"
                     /translation="MKFFLDTANVAAIKAINELGVVDGVTTNPTIISREGRDFETVIK
                     EICDIVDGPISAEVTGLTADAMVEEARSIAKWHDNVVVKIPMTTEGLKATNILSKEGI
                     KTNVTLIFTVSQGLMAMKAGATYISPFIGRLEDIGTDAYQLISDLREIIDLYDFQAEI
                     IAASIRTTAHVEAVAKLGAHIATIPDPLFAKMTQHPLTTNGLKTFMEDWASFKK"
     gene            10715..12700
                     /gene="tkt"
                     /locus_tag="ACF4ZO_000365"
     CDS             10715..12700
                     /gene="tkt"
                     /locus_tag="ACF4ZO_000365"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013793690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004802 - transketolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HFD5485944.1"
                     /translation="MTFDAIDQLAVNTVRTLSMDAIQAANSGHPGLPMGAAPMAYVLW
                     NHFMNINPKTSRNWSNRDRFILSAGHGSAMLYSLLHLAGYDLSVEDLKNFRQWGSKTP
                     GHPEVNHTDGVEATTGPLGQGIANAVGMAMAEAHLAAKFNKPGFDIVDHYTFALNGDG
                     DLMEGVSQEAASMAGHLKLGKLVLLYDSNDISLDGPTSMAFTEDVKGRFEAYGWQHIL
                     VKDGNDLEEIAAAIEAAKAETEKPTIIEVKTIIGFGAEKQGTSAVHGAPLGAEGIAFA
                     KKAYQWTHQDFEVPAEVTERFAQGLQARGEKAEQAWNDLFAAYEAEYPELAAEYQKAF
                     ANEAAQVELEAHELGSSMASRVSSQQAIQQISEQVASFWGGSADLSASNNTMVKAETD
                     FQPGHYEGRNVWFGVREFAMAAAMNGIALHGGTRVYGGTFFVFSNYLLPAVRMAALQN
                     LPTVYVMTHDSIAVGEDGPTHEPIEQLASVRSMPNLNVIRPADGNETNAAWKRAIAET
                     DRPTMLVLTRQNLPVLEGTKELAEDGLNKGAYILSEAKGDLEGILIATGSEVKLAMDT
                     QEALEAEGIHVRVVSMPSQNIFDEQSAEYKESILPAAVTKRLAIEAGSSFGWAKYVGL
                     AGKTLTIDTWGASAPGNRIFEEYGFTVANATELYKSL"
     gene            12892..13158
                     /locus_tag="ACF4ZO_000366"
     CDS             12892..13158
                     /locus_tag="ACF4ZO_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009881243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HFD5485945.1"
                     /translation="MEKKRQRLYDVIRHAYDYPENRENVALSQLLLAASNRLIKHSNP
                     LLVAYQLNQDVDNYLLDNDILLPKSLCRFKQSLEKYILEEASSV"
     gene            13192..13926
                     /locus_tag="ACF4ZO_000367"
     CDS             13192..13926
                     /locus_tag="ACF4ZO_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD5485946.1"
                     /translation="MIEFKHVSKLYGDKEALSDLNVTINDGEIFGLIGHNGAGKTTTI
                     SILTSIIEASYGEVFVDGQLLTENREAIKKQIAYVPDSPDIFLNLTPNEYWQFLAKIY
                     GVSDEDREERLAQLTTLFELKEEGNQTIDSFSHGMRQKVIVIGALVSNPNIWILDEPL
                     TGLDPQASFDLKEMMKAHAASGHTVLFSTHVLSVAEQLCDRIGILKKGKLIFVGTIDE
                     LKEHHPDKDLESIYLELAGRKAQEEG"
     gene            13931..15559
                     /locus_tag="ACF4ZO_000368"
     CDS             13931..15559
                     /locus_tag="ACF4ZO_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD5485947.1"
                     /translation="MNWSTIWELIKINILYSNPQSLANLKKRQENHPKENFKAYKSMM
                     RQQALMIAMFLVIYLFMFIGVDFSHYPGLFSFDVAMFFIMSTLTAFSSLYTIFYESND
                     LKLYIHLPVTSEELYIAKIVSSLGMGAVFLMPLISLLLIAYWQLLGNPLSILVAIVLF
                     LVLLVSSMVLAIYINAWVGKIIVRSRKRKLISTIMMFVSTFGAFVLIFAINISNNKRT
                     MTDGVFTDYPTIPYFKGFYDVIQAPFSTAALLNFWLPLLLILAMVYGIVTKVMPTYYR
                     EAFYISNENKAKQTKKPVNRPHQNQSLTQLLRKHHLLTLQNATLLTQTYLMPLMYVML
                     FIGPSLSRGTGFFKHISPDYFGVALLFGVSLGVMCATPTSFIGVGISLEKDNFTFIKS
                     LPITLKKFLLDKFCLLVGLQLIVPMVIYLVFGLFVLHLHPLLTIAFCLGYALSLIVQG
                     ELMYRRDYRLLDLKWQDMTQLFTRGNGQWLTMGLIFGNLIVTGVVGFGAVIIANIIQQ
                     PLLISILLSCLTLMVLGIAHLWIQKTFWKSLEKL"
     gene            15623..16444
                     /gene="proB"
                     /locus_tag="ACF4ZO_000369"
     CDS             15623..16444
                     /gene="proB"
                     /locus_tag="ACF4ZO_000369"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004349 - glutamate 5-kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HFD5485948.1"
                     /translation="MMKRQFEDVTRIVIKIGTSSLVLPTGKINLEKIDQLAFVISSLM
                     NKGKEVILVSSGAMGFGLDILKMEKRPTNLAKQQAVSSVGQVAMMSLYSQIFAHYQTN
                     VSQILLTRDVVVFPESLANVTNAFESLISLGIVPIVNENDAVSVDEMDHATKFGDNDR
                     LSAVVAGITKADLLIMLSDIDGLFDKNPTIYEDAQLRSHVAVITQEIIASAGGAGSKF
                     GTGGMLSKVQSAQMVFENKGQMVLMNGANPRDVLRVLEGQPLGTWFKQIEEVTHD"
     gene            16437..17687
                     /locus_tag="ACF4ZO_000370"
     CDS             16437..17687
                     /locus_tag="ACF4ZO_000370"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004350 - glutamate-5-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HFD5485949.1"
                     /translation="MTDMRRLGQRAKQASLLIAPLSTQIKNRFLSTLAKALVDDTQTL
                     LAANQKDLANAKEHGISDIMMDRLRLTSERIKAIAQGVQQVADLADPIGQVIKGYTNL
                     DGLKILQKRVPLGVIAMIFESRPNVSVDAFSLAFKTNNAIILRGGKDALHSNKALVKL
                     IRQSLEKSGITPDAVQLVEDPSHAVAEELMQATDYVDVLIPRGGAKLIQTVKEKAKVP
                     VIETGVGNVHIYVDAQADLDMATNIVINAKTKRPSVCNAAEGLVIHEAVAARFIPMLE
                     KAINQVQPVEWRADDKALPLFEQAVPAKAEDFETEFLDYIMSVKVVSSLEEAISWINQ
                     HTSHHSEAIITRDIKAAETFQDLVDAAAVYVNASTRFTDGFVFGLGAEIGISTQKMHA
                     RGPMGLEALTSTKFYINGDGHIRE"
     gene            17707..17928
                     /locus_tag="ACF4ZO_000371"
     CDS             17707..17928
                     /locus_tag="ACF4ZO_000371"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5485950.1"
                     /translation="MTNEREKEEAKVALEELLHQIQVIHLELKIVRNWGYFDLFGDGM
                     LVSWIKRRKMSKVNQLLIDLQVTLQNCRR"
     gene            17929..18135
                     /locus_tag="ACF4ZO_000372"
     CDS             17929..18135
                     /locus_tag="ACF4ZO_000372"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5485951.1"
                     /translation="MANVDRLLLADLPNMSWDKTFDIWLDNLLTDCCVIKEAKNFLQA
                     VEILEAAAKSVLAKLADSEQKEQD"
     gene            18222..19172
                     /gene="rsmH"
                     /locus_tag="ACF4ZO_000373"
     CDS             18222..19172
                     /gene="rsmH"
                     /locus_tag="ACF4ZO_000373"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016434 - rRNA (cytosine)
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HFD5485952.1"
                     /translation="MTKEFHHVTVLLHETVDMLDIKPDGIYVDATLGGSGHSAYLLSK
                     LGEEGHLYCFDQDQKAIDNAQVTLKSYIDKGQVTFIKDNFRHLKARLTALGVDEIDGI
                     LYDLGVSSPQLDERERGFSYKQDAPLDMRMDRQSLLTAYEVVNTYPFNDLVKIFFKYG
                     EDKFSKQIARKIEQARAIKPIETTTELAELIKAAKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQEAMELLALDGRISVITFHSLEDRLTKQLFKEASTVDVPKGLPLIPE
                     DMKPKFELVSRKPILPSHSELAANKRAHSAKLRVAKKIRK"
     gene            19177..19500
                     /gene="ftsL"
                     /locus_tag="ACF4ZO_000374"
     CDS             19177..19500
                     /gene="ftsL"
                     /locus_tag="ACF4ZO_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HFD5485953.1"
                     /translation="MTNEKRTQAVTNALQKRIKTFSRIEKAFYTAIIVTAITMAVSII
                     YLQSRKLQLQQEITSLNSHISDQKLELNNAKQEVNELSRRDRIIDIAGKAGLSNRNNN
                     IKKVE"
     gene            19504..21759
                     /gene="pbp2X"
                     /locus_tag="ACF4ZO_000375"
     CDS             19504..21759
                     /gene="pbp2X"
                     /locus_tag="ACF4ZO_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein PBP2X"
                     /protein_id="HFD5485954.1"
                     /translation="MKKWQKYVLDYVVRDRRTPVENRVRVGQNMMLLTIFIFFIFIIN
                     FMIIIGTDQKFGVSLSEGAKKVYQETVTIQAKRGTIYDRNGTAIAVDSTTYSIYAILD
                     KSFVSASDEKLYVQPSQYETVADILKKHLGMKKTDVIKQLKRKGLFQVSFGPSGSGIS
                     YSTMSTIQKAMEDAKIKGIAFTTSPGRMYPNGTFASEFIGLASLTEDKKTGVKSLVGK
                     TGLEASFDKILSGQDGVITYQKDRNGTTLLGTGKTVKKAIDGKDIYTTLSEPIQTFLE
                     TQMDVFQAKSNGQLASATLVNAKTGEILATTQRPTYNADTLKGLENTNYKWYSALHQG
                     NFEPGSTMKVMTLAAAIDDKVFNPNETFSNANGLTIADATIQDWSINEGISTGQYMNY
                     AQGFAFSSNVGMTKLEQKMGNAKWMNYLTKFRFGFPTRFGLKDEDAGIFPSDNIVTQA
                     MSAFGQGISVTQIQMLRAFTAISNNGEMLEPQFISQIYDPNTASFRTANKEVVGKPVS
                     KKAASETRQYMIGVGTDPEFGTLYSKTFGPIIKVGDLPVAVKSGTAQIGSEDGSGYQD
                     GGLTNYVYSVVAMVPADKPDFLMYVTMTKPQHFGPLFWQDVVNPVLEEAYLMQDTLTK
                     PVVSDANRQTTYKLPNFVGKNPGETSSELRRNLVQPVVLGTGSKIKKVSHQSGQTLTE
                     NQQVLILSDRFVEVPDMYGWTKSNVETFAKWTGIDISFKGTDSGRVMKQSVDVGKSLK
                     KIKKMTITLGD"
     gene            21761..22771
                     /gene="mraY"
                     /locus_tag="ACF4ZO_000376"
     CDS             21761..22771
                     /gene="mraY"
                     /locus_tag="ACF4ZO_000376"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008963 -
                     phospho-N-acetylmuramoyl-pentapeptide-transferase activity
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HFD5485955.1"
                     /translation="MFLTLIAAIISFMVSAFTMPYFIKFYQLKKIGGQQMHEDVKQHL
                     AKAGTPTMGGTVFLLVATAVSLLVSLFSIKNTQSLALISGILSIVVIYGIIGFLDDFL
                     KIFKQINEGLTAKQKLALQLAGGLMFYFLHVSPSGISSINVFGYQLSLGIFYLFFVLF
                     WVVGFSNAVNLTDGIDGLASISVVISLVTYGVIAYVQGQFDVLLLIGTMIGALLGFFL
                     FNHKPAKVFMGDVGSLALGAMLAAISIALRQEWTLLIIGIVYVLETSSVMLQVSYFKY
                     TKKKYGEGRRIFRMTPFHHHLELGGLSGKGKKWSEWQVDAFLWGVGSLASLLVLAILY
                     VF"
     gene            22929..24272
                     /locus_tag="ACF4ZO_000377"
     CDS             22929..24272
                     /locus_tag="ACF4ZO_000377"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HFD5485956.1"
                     /translation="MSFKDYHFKQYVQQALEEIGFVNPTEVQQRLIPIVNSGRDLVGE
                     SKTGSGKTHTFLLPIFEKLDEAKAEVQVVITAPSRELATQIFDACKQIAKHSQEEIRL
                     ANYVGGTDKLRQIEKLKGSQPHIVIGTPGRIYDLVKSGDLAIHKATTFVVDEADMTMD
                     MGFLDTVDKIAASLPKSVQILVFSATIPQKLQPFLKKYLTNPVIEQIKTKTVIADTID
                     NWLVSTKGRDKNGQLLEILKTMQPYMAMLFVNTKERADDLHAFLTANGLKVAKIHGGI
                     PPRERKRIMNQVKKLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGMAGTAITLYQPSDDSDIKELEKMGIAFTPKVLKNGEFQDTYDRDRRQNREKAYQK
                     LDTEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKERRAENRAKGRAERKAKKQHF"
     gene            24467..25270
                     /locus_tag="ACF4ZO_000378"
     CDS             24467..25270
                     /locus_tag="ACF4ZO_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HFD5485957.1"
                     /translation="MTSVFLTSGWAFYDHLISPIPHGKLFSWHAVFDAIPNIIQRLPI
                     TLGLTLSGATFGLVLALIFALVKINKVKLLYPIQAIFVSFLRGTPILVQLMLTYYGIP
                     LFLKFLNQKYGFDWNVNAIPASIFAITAFAFNEAAYASETIRAAILSVDTGEIEAAKS
                     LGMTSVQVYRRVIIPNATVVAIPTLINGLIGLTKGTSLAFNAGIVEMFAQAQILGGSD
                     YRYFERYISVALVYWSISILMEQVGRLIENKMAIKAPEQARNEKLGELR"
     gene            25270..26013
                     /locus_tag="ACF4ZO_000379"
     CDS             25270..26013
                     /locus_tag="ACF4ZO_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HFD5485958.1"
                     /translation="MITIRNLSKTFSGQKVLDSLALDIEKGQVIALVGASGAGKSTFL
                     RSLNYLEKPDSGSISIGDFTVDFETITTERVLILRRKLAMVFQQFNLFERRTALENVK
                     EGLKVVKKLSDQEATKLAQAELAKVGLADRKHHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSITDAAKSGQTMVLVSHDMNFVYQVADRVLFLDQGKIL
                     EQGTPEEVFRHPQKERTKEFFASYSKTYI"
     gene            26117..26341
                     /locus_tag="ACF4ZO_000380"
     CDS             26117..26341
                     /locus_tag="ACF4ZO_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HFD5485959.1"
                     /translation="MLVEIFSLYVKGLILSSLTMILICLIWTLWRAKTKRDKTLIERQ
                     AFLYEMLMVAILTIPILSFAFMSILVVIKS"
     gene            26405..27322
                     /gene="trxB"
                     /locus_tag="ACF4ZO_000381"
     CDS             26405..27322
                     /gene="trxB"
                     /locus_tag="ACF4ZO_000381"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004791 - thioredoxin-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA];
                     GO_process: GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HFD5485960.1"
                     /translation="MYDTLIIGSGPAGMTAALYAARSNLSVAIIEQGAPGGQMNNTFD
                     IENYPGYDHISGPELAMKMYEPLEKFNVENIYGIVQKIENFGDYKCVLTEDASYEAKT
                     VIIATGAKYRVLGVPGEEYYTSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEAIYLT
                     QFAKKVTVVHRRDQLRAQKILQDRAFANDKVDFIWDSVVKEIKGNDIKVSNVLIENVK
                     TGQVTDHAFGGVFIYVGMIPVTGMVKDLKITDSEGWIITDDHMRTSIPGIFAIGDVRQ
                     KDLRQITTAVGDGAIAGQGVYHYLESFPS"
     gene            27491..28870
                     /locus_tag="ACF4ZO_000382"
     CDS             27491..28870
                     /locus_tag="ACF4ZO_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFD5485961.1"
                     /translation="MSIKEQTDNNELENGMVRGLENRHVQLIAIAGTIGTGLFLGAGR
                     SIALTGPSIIFVYMITGAFMFMMMRAIGEMLYYDPDQHTFINFISKYIGPGWGYFSGL
                     SYWISLIFIGMAEITAVGAYVQFWFPSWPAWLIQLVFLVLLSSINLIAVRVFGETEFW
                     FAMIKILAILALIATAIFMVLTGFETHTGHASLSNIFDHFSMFPNGKLKFFMAFQMVF
                     FAYQAIEFVGITTSETANPRKVLPKAIQEIPTRIVIFYVGALVSIMAIVPWHQLPVDE
                     SPFVMVFKLIGIKWAAALINFVVLTSAASALNSTLYSTGRHLYQIANETPNALTNRLK
                     INTLSRQGVPSRAIIASAVVVGISALINILPGVADAFSLITASSSGVYIAIYALTMIA
                     HWKYRQSKDFMADGYLMPKYKVTTPLTLAFFAFVFISLFLQESTYIGAIGATIWIIVF
                     GIYSNVKFK"
     gene            29041..30495
                     /locus_tag="ACF4ZO_000383"
     CDS             29041..30495
                     /locus_tag="ACF4ZO_000383"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004516 - nicotinate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HFD5485962.1"
                     /translation="MYKDDSLTLHTDLYQINMMQVYFEQGIHNRHAVFEVYFRQEPFN
                     NGYAVFAGLQRMVEYLEQFQFSETDLAYLEELGYPENFLTYLKELRLELTIRSAKEGD
                     LVFANEPIVQVEGPLGQCQLVETALLNIVNFQTLIATKAARIRSVIEDEPLLEFGTRR
                     AQELDAAIWGTRAAMIGGADATSNVRAGKRFDIPVSGTHAHALVQAYGNDYDAFMAYA
                     KTHKDCVFLVDTYDTLKVGVPTAIRVAKELGDKINFLGVRLDSGDLAYLSKTVRQQLD
                     DAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVSIE
                     QEDGSMRDTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITFTDINVNELTEIEM
                     FHPTYTYIKKTVRNFDAIPLLVDIFVKGELVYQLPTLSEIKAYAKKEFDKLWDEYKRV
                     LNPQDYPVDLARDVWQNKMALIDNIRKDAYGKSE"
     gene            30497..31321
                     /gene="nadE"
                     /locus_tag="ACF4ZO_000384"
     CDS             30497..31321
                     /gene="nadE"
                     /locus_tag="ACF4ZO_000384"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003952 - NAD+ synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_function: GO:0008795 - NAD+ synthase activity [Evidence
                     IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HFD5485963.1"
                     /translation="MTLQEEIIRQLGVKASIDPKEEIRKTVDFLKAYLRKHSFLKTYV
                     LGISGGQDSTLAGKLAQMAIAELREETGDQAYQFIAVRLPYGVQADEADAQKALAFIA
                     PDQTLTINIKAAVDGQVEALQAAGVEISDFNKGNIKARQRMISQYAIAGQMAGAVIGT
                     DHAAENITGFFTKFGDGGADILPLFRLNKRQGKALLKVLGADAALYEKVPTADLEDQK
                     PGLADEVALGVTYQDIDDYLEGKLISKVAQATIEKWWHKGQHKRHLPITIFDDFWK"
     gene            31506..32843
                     /gene="pepC"
                     /locus_tag="ACF4ZO_000385"
     CDS             31506..32843
                     /gene="pepC"
                     /locus_tag="ACF4ZO_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HFD5485964.1"
                     /translation="MSALTETFTEQLFAHYEANAKFSAIENAVTHNGLLKSLETRQSE
                     VDNDFVFSIDLTKDKVSNQKASGRCWMFAALNTFRHKLITEFKLENFELSQAHTFFWD
                     KYEKANWFMEQVIATADQELTSRKVKFLLDVPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESISSSNSRELNQYLNKLLRQDAQILRDLIASGAKADQVVDRKAELLQEIFNFLAMTL
                     GLPPRHFDFAYRDKDDHYHVEKGLTPQAFYDKFVGLKLSNYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSREVRYLNLDMKRFKELAIKQMQAGESVWFGSDVGQVSDRQKGILATN
                     TYDFEASMDINLSQDKAGRLDYSESLMTHAMVLTGVDLDETGKPLKWKVENSWGEKVG
                     DKGYFVASDAWMDEYTYQIVVRKEFLTADELAAYEKEPQVLAPWDPMGALAQY"
     gene            complement(33310..35475)
                     /gene="pbp1a"
                     /locus_tag="ACF4ZO_000386"
     CDS             complement(33310..35475)
                     /gene="pbp1a"
                     /locus_tag="ACF4ZO_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein PBP1A"
                     /protein_id="HFD5485965.1"
                     /translation="MITIKNPKILKWLKYVLSAILSLIILVIIIGGLLFTFYISSAPK
                     LSEAQLKSTNSSLVYDGNNNLIADLGSEKRENVTADSIPINLVNAITSIEDKRFFNHR
                     GVDLYRIFGAAFHNLTSQTTQGGSTLDQQLIKLAYFSTNESDQTLKRKAQEVWLALQM
                     ERKYTKQEILTFYINKVYMGNGNYGMLTAAKSYYGKDLKDLSYAQLALLAGIPQAPSQ
                     YDPYLHPEAAKNRRNVVLQQMYMEKHLTKAEYETAIATPVAEGLQSLQQRSTYPKYMD
                     NYLKQVIEEVKKETNKDIFTAGLKVYTNIIPDAQQTLYNIYHSGDYVYYPDQDFQVAS
                     TIVDVTNGHVIAQLGGRNQDENVSFGTNQAVLTDRDWGSTMKPITAYAPAIESGVYTS
                     TAQSTNDSVYYWPGTTTQLFNWDLRYNGWMTIQAAIMLSRNVPAVRALEAAGLDYARS
                     FLSSLGINYPEMHYSNAISSNNSSSDKKYGASSEKMAAAYAAFANGGIYHKPRYVNKV
                     EFSDGTSKTFDEKGKRAMKETTAYMMTDMLKTVLTYGTGTAAAIPGVAQAGKTGTSNY
                     TDEELAKIGEKYGLYPDYVGTLAPDENFVGFTKRYAMAVWTGYKNRLTPVYGSSLEIA
                     SDVYRSMMTYLTNGYSEDWTMPNGLYRSGGFLYLSGTYASNTDYTNSVYNNLYSNNTT
                     TASSQTTSDDTSSSNDTSNSTNTDNNGSHPSTDDKKTTH"
     gene            complement(35462..36070)
                     /gene="recU"
                     /locus_tag="ACF4ZO_000387"
     CDS             complement(35462..36070)
                     /gene="recU"
                     /locus_tag="ACF4ZO_000387"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HFD5485966.1"
                     /translation="MVNYPHNLIRQKVSSVQKQTKQNKVDFANRGMSFEAAINATNDY
                     YLSRQIAVIHKKPTPVQIVKVDYPKRSRAKIVEAYFRQASTTDYCGVYKGHYVDFEAK
                     ETRQKTAMPMKNFHLHQIEHMACVLHQKGICFVLLHFSTLKETYYLPAQALISFYQID
                     NGSKSMPIDYIRKNGFKVAFGAFPQVPYLNIIEQNFLGGDYN"
     gene            36151..36666
                     /locus_tag="ACF4ZO_000388"
     CDS             36151..36666
                     /locus_tag="ACF4ZO_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HFD5485967.1"
                     /translation="MTAILITGYRSFEIGIFDHKDPRVSIIKQAIRKDLIGYLENGVD
                     WFIFTGNLGFEQWALEVANELKEEYPLQIGTIFLFETHGDRWNEKNQEVLSQFRAVDF
                     VKYYFPNYEQPTQFSQYYQFLLEKTEGAYVFYDTENETNLKYFLKKAKDMPHYQLLLL
                     TFDRLNDMSQS"
     gene            36788..37114
                     /gene="gpsB"
                     /locus_tag="ACF4ZO_000389"
     CDS             36788..37114
                     /gene="gpsB"
                     /locus_tag="ACF4ZO_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HFD5485968.1"
                     /translation="MTSIIYSPKDIFEQEFKTSMRGFDKKEVDEFLDNVIKDYENFNA
                     QIEALKAENEALKKAKFQARNTVSATVQQPVPQPTRVAQSATNFDILKRISKLEKEVF
                     GKQIIE"
     gene            37128..37496
                     /gene="rnpB"
                     /locus_tag="ACF4ZO_000390"
     ncRNA           37128..37496
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="ACF4ZO_000390"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            37559..38713
                     /locus_tag="ACF4ZO_000391"
     CDS             37559..38713
                     /locus_tag="ACF4ZO_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HFD5485969.1"
                     /translation="MKETFRLVATAAAGLEAVVGKEVRALGFDCQVENGKVYFEGDVE
                     AIVKTNLWLRAADRIKIIVGQFPARTFEELFQGVFALDWENYLPLGAKFPISKAKCVK
                     SKLHNEPSVQAITKKAVVKKLQKHFHRPEGVPLQEVGSTFNIEVSILKDQATIMIDTT
                     GSSLFKRGYRVQKGGAPIKENMAAAILALSNWFPDKPLVDPTCGSGTFCIEAALIGMN
                     IAPGFNRSFAFEEWSWVDKDMVQQVRDDAEQEANYEIELDISGFDIDGRMIEIAKSNA
                     EEAGLSDVITFKQMRLQDFRTDKINGVVISNPPYGERLLDDKAVDILYNEMGQTFAPL
                     KTWSKFILTSDELFELKYGQKADKKRKLYNGTLKVDLYQFYGERIKRHLI"
     gene            38727..40196
                     /locus_tag="ACF4ZO_000392"
     CDS             38727..40196
                     /locus_tag="ACF4ZO_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division site-positioning protein MapZ
                     family protein"
                     /protein_id="HFD5485970.1"
                     /translation="MSEESKEVEVTKESQTLGLNEAKSMTIGEAVRKQSEIKAGVTKD
                     DSILDKYIKQHRDEVSSQKFDAKYTELDTASLDNFIKKQREALSKAGLVDDEPVSAES
                     AEQDSTLVEEVAEDLAPMETTAVVTGIPVEATVPVLDLDPSERVIPEPQITKEEPKRD
                     QFLSEDSHHPAKQNTKKGWLIALFLLLLAILAVVFGWNHFLRQDSGKTTQTASKQTKT
                     SLQTDSAKKATRLKAAAKAFEKQYGTFYTDATKSKLKNSAFATLPDLEAALKALEGSA
                     YYDKAKAKVDSLKKAIAAITAVNGKFVSDVVVDGEKVSAEIKADANFDDLSSATLTTG
                     NANLDAVLQASITEGRQQLASKAEAAKAANEQEAQDQAAQGQSTLVAPSGYGLTSYDP
                     ASLQRHLSRVPYNQDVIADRANPSWAFNPGVLEKIVATSQARGYISGNQYILEPVNII
                     NGNGYYNMFKPDGTYLFSINCKTGYFVGNGKGYADALDY"
     gene            complement(40341..40823)
                     /locus_tag="ACF4ZO_000393"
     CDS             complement(40341..40823)
                     /locus_tag="ACF4ZO_000393"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HFD5485971.1"
                     /translation="MTKEVIVESFELDHTIVKAPYVRLISEEFGPKGDRITNFDVRLV
                     QPNQNSIETAGLHTIEHLLAKLIRQRIDGMIDCSPFGCRTGFHLIMWGKHSSTDIAKV
                     IKSSLEEIATGITWEDVPGTTLESCGNYKDHSLFAAKEWAQLIIDQGISDDPFSRHVI
                     "
     gene            complement(40897..42228)
                     /locus_tag="ACF4ZO_000394"
     CDS             complement(40897..42228)
                     /locus_tag="ACF4ZO_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HFD5485972.1"
                     /translation="MEIIGSLGVLVGVIVIIYLSVKEVNIIIAAPLATSLVIWFNQMD
                     PTTTLLGKEPNQFMGALSTYILNYFAIFLLGSILAKLMETSGATTSIADYILKKVGHD
                     SPYKVLVAIFLISAILTYGGISLFVVMFAVLPLARSLFKKMDLAWNLIQVPLWLGIAT
                     FTMTILPGTPAIQNVIPIQYLDTSLTAAAIPSIVGSIGCVTFGLFYMKYCLAKSMARG
                     ETYTTYAFDNEIQVKTKNLPHFLASILPLLLLIIIALTGSLFGNDFFKKNIIFIALLA
                     AILTASWLFRQFIPNKIAVFNLGASSSIAPIFATASAVAFGAVVMIAPGFTFFSDLIL
                     NIPGNPLISLAVLTSSMSAITGSSSGALGIVMPNFAQYYLDQGLNLEMIHRVATIASN
                     IFTIVPQSGVFLTFLALTGLNHKNAFKETFITVSVSTFIAQVIMIAFDLFS"
     gene            complement(42299..43078)
                     /locus_tag="ACF4ZO_000395"
     CDS             complement(42299..43078)
                     /locus_tag="ACF4ZO_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxybutyrate dehydrogenase"
                     /protein_id="HFD5485973.1"
                     /translation="MTHTKEVAFITGAASGIGKQIGETLLKEGKTVVFSDINQEKLDQ
                     VVADYTKEGYDAFSVVCDVTKEEAINAAIDTVVEKYGRIDILVNNAGLQHVAMIEDFP
                     TEKFEFMIKIMLTAPFIAIKRAFPTMKAQKHGRIINMASINGVIGFAGKSAYNSAKHG
                     LIGLTKVTALEAADSGITVNAICPGYVDTPLVRGQFEDLSKTRGIPLENVLEEVPYPP
                     VPQKRLIDVQEIADYVSFLASDKAKGVTGQACILDGGYTAQ"
     gene            complement(43111..43770)
                     /locus_tag="ACF4ZO_000396"
     CDS             complement(43111..43770)
                     /locus_tag="ACF4ZO_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008410 - CoA-transferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacid CoA-transferase subunit B"
                     /protein_id="HFD5485974.1"
                     /translation="MGTSATVLSKEEIQTRIAKRVAQELEHNTLVNLGIGLPTKVANY
                     IPEGVTITLQSENGFVGLTGLTDDHYDPSIVNAGGQPVSIAPGGAFFDSSTSFGIIRG
                     GHVAATVLGALQVDKEASIANYLIPGKMVPGMGGAMDLLVGAKKVIVAMEHTNKGKAK
                     ILDKCTLPLTVQNVVNLIITEMGVFEYQDEGLCALEINPDYTFEDVQNVTEVTLIDKT
                     N"
     gene            complement(43772..44422)
                     /locus_tag="ACF4ZO_000397"
     CDS             complement(43772..44422)
                     /locus_tag="ACF4ZO_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008410 - CoA-transferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase subunit A"
                     /protein_id="HFD5485975.1"
                     /translation="MCKEITIKEAVAHVKDGDTIMVGGFMTNGTPEKLIDALVEKGVK
                     DLTLICNDAGFPDKGVGKMVANKQFSTIIASHIGLNCEAGRQMTEGETVIDLVPQGTL
                     AERIRSGGFGLGGFLTPTGIGTEVAKGKEVITIDGKDYLLEKPLKADVALIFANKADK
                     NGNLQYAGSENNFNHVMAANAKTTIVEAREIVDVGQMDPNFVHTPGIFVNYLVKGA"
     gene            complement(44446..45633)
                     /locus_tag="ACF4ZO_000398"
     CDS             complement(44446..45633)
                     /locus_tag="ACF4ZO_000398"
                     /EC_number="2.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HFD5485976.1"
                     /translation="MKNIVIVEALRTPIGAFGGSFKSVSAVELGTTVLKKILDKTQVK
                     PEMVDEVILGNVLHAGLGQNVARQVAIHSGIPEDKTAFTLDMVCGSGLKAIQLAAQSI
                     MLGDADIVIAGGVENMSQAAYVSTQHRFGQRLGNSQLIDTLVHDGLTDAFNNYHMGIT
                     AENVAQKYGISREEQDQFALESQEKAAKALENHRFADEIVPVSVPQRRKDPLIVTTDE
                     YPKVDTSLEKLQQLRPAFFPKEGTVTAGNASGINDGAALLMLMTEEKALELGLTPLVT
                     IESYASAGVAPELMGTGPIPATQKALKKAGLTISDLDLVESNEAFAAQSLAVLKDLKL
                     NPEIVNVNGGAIALGHPIGASGARILVTLIHEMKKRQVTRGLATLCIGGGQGTAVIVK
                     NNT"
     gene            45832..46728
                     /locus_tag="ACF4ZO_000399"
     CDS             45832..46728
                     /locus_tag="ACF4ZO_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFD5485977.1"
                     /translation="MDIKQIRYFIAIVENHFNLSQAAELLYVSQPTLSMMINDFEKRE
                     NVKLFKRKRGRIIGLTYLGDNYYKDAQKVLGLYDDMFLKLHDHSKGLKGSINIGIPPL
                     ILSVVFSEVMPKLILENPGIQFNVKEIGAYQLKNELLVGNVDVAVLLSPTGIADNLVE
                     TYEIQRSELSVCLSPRHRLASKKVIQWEDLTDEQLALFDPSFMVHHLVLEACERHQVR
                     PNIILTSSSWDFMLNSTKINHNVLTICPKPITELYQLKDIKCIPMERPISWRVVLTRL
                     RKKSYSEIEAYIMDDLLQSFFK"
     gene            46858..48465
                     /locus_tag="ACF4ZO_000400"
     CDS             46858..48465
                     /locus_tag="ACF4ZO_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HFD5485978.1"
                     /translation="MVNIILLIVSALIGLILGYALISIRLKSAKEAAELTLLNAEQEA
                     VDIRGKAEVDAEHIKKTAKRESKANRKELLLEAKEEARKYREEIEQEFKSERQELKQL
                     ETRLAERSLTLDRKDENLSSKEKVLDSKEQSLTDKSKHIDERQLQVEKLEEEKKAELE
                     KVAAMTIAEAREVILMETENKLTHEIATRIRDAERDIKDRTVKTAKDLLAQAMQRLAG
                     EYVTEQTITSVHLPDDNMKGRIIGREGRNIRTLESLTGIDVIIDDTPEVVILSGFDPI
                     RREIARMTLESLIADGRIHPARIEELVEKNRLEMDNRIREYGEAAAYEIGAPNLHPDL
                     IKIMGRLQFRTSFGQNVLRHSVEVGKLAGILAGELGENVALARRAGFLHDMGKAIDRE
                     VEGSHVEIGMEFARKYKEHPVVVNTIASHHGDVEPDSVIAVLVAAADALSSARPGARN
                     ESMENYIKRLRDLEEIATSFDGVQNSFALQAGREIRIMVQPEKISDDQVVILSHKVRE
                     KIENNLDYPGNIKVTVIREMRAVDYAK"
     gene            48575..49210
                     /gene="gmk"
                     /locus_tag="ACF4ZO_000401"
     CDS             48575..49210
                     /gene="gmk"
                     /locus_tag="ACF4ZO_000401"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004385 - guanylate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HFD5485979.1"
                     /translation="MSERGLLIVFSGPSGVGKGTVRQEIFSTPDHKFEYSVSMTTRPQ
                     RPGEVDGVDYFFRTREEFEELIKTGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKSKVPDGVFVFLTPPDLDELEDRLVGRGTDSQEVIAQRIERAKEEIALM
                     REYDYAVVNDEVALAAERVKRIIETEHFRVERVIGRYDKMIKITKNPFKAK"
     gene            49226..49543
                     /gene="rpoZ"
                     /locus_tag="ACF4ZO_000402"
     CDS             49226..49543
                     /gene="rpoZ"
                     /locus_tag="ACF4ZO_000402"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000979238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HFD5485980.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILQAKRAHELEAGATPTQEFKSV
                     KSTLQALEEIESGNVVIHPDPSAKREAVRAKIEAERLAKEEEERKIKEQIAKEKEEEG
                     EKI"
     gene            49608..51992
                     /locus_tag="ACF4ZO_000403"
     CDS             49608..51992
                     /locus_tag="ACF4ZO_000403"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HFD5485981.1"
                     /translation="MEKVAHVIVDIPLMQTDKPFSYGIPKELVSLVQLGSRVHVPFGK
                     GNRLLQGFIIGFGQEDSSSLKLIQTVLDPEPVLNQEQLTLADQLRKTVFSYKITLLKA
                     MIPNLLNSNYDKVLRPESGLKKPDRDFLFEGQPSVLYSTLDREKGKIALKGIQAGHIT
                     VSYLAKDKKNLKTEKYYHVDLDALAVHPISSRAKKRQLLKDYLLTHTKEAKLATLYQA
                     FSRDVVTYFVTNHLIRIDERPIDRSESYFDQIKPSSFLTLNEQQASAVTEIVEQIGKP
                     SKPFLIEGITGSGKTEVYLHIIEAVLKQDKTAIVLVPEISLTPQMTSRFISRFGKQVA
                     IMHSGLSDGEKFDEWRKIKTGQAKVVVGARSAIFSPLERIGAIIIDEEHESTYKQESN
                     PRYHAREVALLRAKHHQAVVVMGSATPSIESRARASKGVYHFIQLTQRANPLAKIPEV
                     TIVDFRDYIGQQAVSNFTPYLIDKIKERLVKKEQVVLMLNRRGYSSFVTCRDCGYVDK
                     CLNCDISLTLHMDTKTMNCHYCGFQKPIPITCPECYSNSIRYYGTGTQKAFDELQGVI
                     PEARILRMDVDTTRKKRSHKTILDSFGRQEADILLGTQMIAKGLDFPNVTLVGVLNAD
                     TSLNLPDFRASEKTFQLLTQVAGRAGRAHKPGEVLIQTYNPDHYAIQLAKKQDFEAFY
                     RYEMAIRRQMAYPPYYFTVGITLSHRLEASVVKKAYQVTELLKSHLSDNIKILGPTPK
                     PIARTHNLYHYQILLKYRFEDNLEETLNRILDWSQEADNRHLKLIIDCEPQQFL"
     gene            52054..52989
                     /gene="fmt"
                     /locus_tag="ACF4ZO_000404"
     CDS             52054..52989
                     /gene="fmt"
                     /locus_tag="ACF4ZO_000404"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004479 - methionyl-tRNA formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0071951 - conversion of methionyl-tRNA to
                     N-formyl-methionyl-tRNA [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HFD5485982.1"
                     /translation="MIKLLFMGTPQFSATVLKGLLDNPAYEILGVVTQPDRAVGRKKD
                     IKVTPVKQLALEHGISIYQPEKLSGSQELIEITGLGADGIITAAFGQFLPTLLLDSVS
                     FAINVHASLLPKYRGGAPIHYAIMNGDKEAGVTIMEMIKEMDAGDVVAKASTPILETD
                     NVGTLFEKLAIIGRDLLLDSLPAYLSGELKPIPQDHSQATFSPNISPEQEKLDWTMSN
                     QEVFNHIRGMNPWPVAHTFLEGQRLKIYEAQLAEGEGLPGQVIVKTKKSLVIATGQGA
                     LSLIVVQPAGKPKMSIIDFLNGIGRKLEVGDIIGR"
     gene            52979..54301
                     /gene="rsmB"
                     /locus_tag="ACF4ZO_000405"
     CDS             52979..54301
                     /gene="rsmB"
                     /locus_tag="ACF4ZO_000405"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003060995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HFD5485983.1"
                     /translation="MADNWKKSTRGKALLVIEAIFDQGAYTNIALNQQLSNKALSAKD
                     RALLTEIVYGTVSRKISLEWYLAHYVKDRDKLDKWVYYLLMLSLYQLTYLDKLPAHAI
                     VNDAVGIAKNRGNKKGAEKFVNAILRQFTNHPLPDMETIKRRNKYYSVKYSLPVWLVK
                     KLEDQFGSDRSVAIMESLFVRSKASIRVTDPLKLEEVAEALDAERSLLSATGLTKASG
                     HFAASDYFTNGDITIQDESSQLVAPTLNIDGDDIILDACSAPGGKTSHIASYLKTGKV
                     IALDLYDHKLELVKENANRLGVADNIETRKLDAREVHRHFEKDSFDKILVDAPCSGIG
                     LIRRKPDIKYNKESQDFNALQAIQLEILSSVCQTLRKGGIITYSTCTIFDEENRQVIE
                     AFLQSHPNFEQVKLNHTQADIVKDGYLIITPEQYQTDGFFIGQVRRVL"
     gene            54339..55079
                     /locus_tag="ACF4ZO_000406"
     CDS             54339..55079
                     /locus_tag="ACF4ZO_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HFD5485984.1"
                     /translation="MKISLKTDIGQKRSNNQDFINKFDNKKGITLVILADGMGGHRAG
                     NIASEMTVTDLGREWVKTDFTELSQIRDWLFETIQSENQRIYDLGQSEDFKGMGTTVE
                     AVALVESSAIYAHIGDSRIGLVHDGHYTLLTSDHSLVNELVKAGQITEEEAASHPQRN
                     IITQSIGQASPVEPDLGVRVLEPGDYLVINSDGLTNMISNDEIVTILGSKVSLDEKNQ
                     EMIDLANLRGGLDNITIALVHNESEDVE"
     gene            55076..56974
                     /gene="pknB"
                     /locus_tag="ACF4ZO_000407"
     CDS             55076..56974
                     /gene="pknB"
                     /locus_tag="ACF4ZO_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004672 - protein kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HFD5485985.1"
                     /translation="MIQIGKLFAGRYRILKSIGRGGMADVYLANDLILDNEDVAIKVL
                     RTNYQTDQVAVARFQREARAMAELNHPNIVAIRDIGEEDGQQFLVMEYVDGADLKRYI
                     QNHAPLSNNEVVRIMEEVLSAMTLAHQKGIVHRDLKPQNILLTKEGVVKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSIIEENHNVPQALENVVIRATAKKLSDRYGSTFEMSRDLMTALSYN
                     RSRERKIVFEDVESTKPLPKVASGPTASVKLSPPTPTVLTQESRLDQTNQTDALQPPT
                     KKKKSGRFLGTLFKILFSFFIVGVALFTYLILTKPTSVKVPNVAGTSLKVAKQELYDV
                     GLKVGKIRQIESDTVAEGNVVRTDPKAGTAKRQGSSITLYVSIGNKGFDMENYKGLDY
                     QEAMNSLIETYGVPKSKIKIERIVTNEYPENTVISQSPSAGDKFNPNGKSKITLSVAV
                     SDTITMPMVTEYSYADAVNTLTALGIDASRIKAYVPSSSSATGFVPIHSPSSKAIVSG
                     QSPYYGTSLSLSDKGEISLYLYPEETHSSSSSSSSTSSSNSSSTNDSTAPGSNTELSP
                     SETTAQTP"
     gene            57097..57789
                     /gene="liaF"
                     /locus_tag="ACF4ZO_000408"
     CDS             57097..57789
                     /gene="liaF"
                     /locus_tag="ACF4ZO_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein
                     LiaF"
                     /protein_id="HFD5485986.1"
                     /translation="MKKFQFFLLIECILLAMGIMTILDNDLSSFILILVLILLALRFY
                     NQDSRNNFLLTVSLLFLFLIFMLNPYIIMAVLLGIVYIFINHFSQVKKKNRFALIRFK
                     EEKIEVNNTKHQWIGTANYESDYYCFDDINIIRISGNDTVDLTNVIVTGMDNIIVIRK
                     IFGNTTILVPIDVTVTLDVSSIYGSVDFFRCQQYDLRNESIKLKETDNQSLKKVKIIV
                     TTIAGNVEVDRR"
     gene            57786..58790
                     /locus_tag="ACF4ZO_000409"
     CDS             57786..58790
                     /locus_tag="ACF4ZO_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFD5485987.1"
                     /translation="MKKRYYALVWLYSTITILSIVFVVMDNLGITFNYLRNHLWQVER
                     LGFSILLLVVSVTLLLLLLWIIMDDNSKRNINQNLKYILNNRRLYLDETSEINTNLSR
                     LSKKMSHLTANMQKKESAYILDSQEVVKQERKRIARDLHDTVSQELFASSLILSGISM
                     SLEQLDKTQLQTQLTTVEAMLQNAQNDLRILLLHLRPTELANRTLSEGLHMILKELTD
                     KSDIEVIYKETIAQLPKTMEDNLFRIAQEFISNTLKHAKASRIEVYLNQTSTELQLKM
                     IDDGVGFDMDQVRDLSYGLKNIEDRVNDLAGNLHLISQKGKGVSMDIRLPIVKGDDDE
                     "
     gene            58783..59424
                     /locus_tag="ACF4ZO_000410"
     CDS             58783..59424
                     /locus_tag="ACF4ZO_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFD5485988.1"
                     /translation="MSKIKVILVDDHEMVRMGLKSFLNLQADIDVVGEASNGREGVDL
                     ALALKPDVLVMDLVMPELGGVEATLEVLKKWKEAKVLVLTSYLDNEKIYPVIDAGAKG
                     YMLKTSSAAEILNAIRKVSKGELAIETEVDKKIKAHDQHPDLHEELTAREYDILHLLA
                     KGYDNQTIADELFISLKTVKTHVSNILAKLEVDDRTQAVVYAFRHHLVPQDDN"
     gene            59461..60861
                     /locus_tag="ACF4ZO_000411"
     CDS             59461..60861
                     /locus_tag="ACF4ZO_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HFD5485989.1"
                     /translation="MDAKLKYKAKKIKMVFFDIDDTLRVKDTGYMPESIQRVFKALKA
                     KGILVGIASGRARYGVPQEVQDLHADYCVKLNGAYVKDDAKTIIFQAPIPADVVVAYK
                     KWADDMGIFYGMAGRHEAVLSARNDMISNAIDNVYAQLEVCPDYNEYHDVYQMWTFED
                     KGDGLQLPAELAEHLRLVRWHDNSSDVVLKGTSKALGVSKVVDHLGLKPENILVFGDE
                     LNDLELFDYAGISIAMGVSHPLLQEKADFITKKVEEDGILYALEELGLIDKELQFPQL
                     DLENHTGPKVTIKTNHGDMTLVLFPDHAPKTVANFLGLAKEGYYDGIIFHRIIPEFMI
                     QGGDPTGTGMGGQSIYGESFEDEFSDELYNLRGALSMANAGPNTNGSQFFIVQNSKIP
                     YAKKELERGGWPTPIAAAYAENGGTPHLDRRHTVFGQLVDETSFQVLDLIAGVETGAQ
                     DKPKEDVIIETIEVFD"
     gene            60861..61238
                     /locus_tag="ACF4ZO_000412"
     CDS             60861..61238
                     /locus_tag="ACF4ZO_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HFD5485990.1"
                     /translation="MKIGDKLHGTITGIKPYGAFVALENGTTGLIHISEIKTGFIDDI
                     DQLLAIGNQVLVQVIDIDEYSKKPSLSMRTLAEEKQHFFHRHRYSNSRHKIGFRPLEE
                     QLPQWIEESLQFLKKNTKKSLEP"
     gene            complement(61256..62197)
                     /gene="cysK"
                     /locus_tag="ACF4ZO_000413"
     CDS             complement(61256..62197)
                     /gene="cysK"
                     /locus_tag="ACF4ZO_000413"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004124 - cysteine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HFD5485991.1"
                     /translation="MTKIYKTITELVGQTPIIKLNRLIPNEAADVYVKLEAFNPGSSV
                     KDRIALSMIEAAEAEGLISPGDVIIEPTSGNTGIGLAWVGAAKGYRVIIVMPETMSLE
                     RRQIIQAYGAELVLTPGAEGMKGAIAKTETLAIELGAWMPMQFNNPANPSIHEKTTAQ
                     EILEAFKEISLDAFVSGVGTGGTLSGVSHVLKKASPETVIYAVEAEESAVLSGQEPGP
                     HKIQGISAGFIPNTLDTKAYDQIIRVKSKDALETARLTGAKEGFLVGISSGAALYAAI
                     EVAKQLGKGKHVLTILPDNGERYLSTELYDVPVIKTK"
     gene            complement(62325..62957)
                     /locus_tag="ACF4ZO_000414"
     CDS             complement(62325..62957)
                     /locus_tag="ACF4ZO_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HFD5485992.1"
                     /translation="MEHFKTIKASGFFEESIKKSRFICHIKRVSTEEDGKNFVNAIKK
                     EHYKANHSCFAMIIGNNRQIKRSSDDGEPSGTAGIPILSVLEKQCLTNVVVVVTRYFG
                     GIKLGTGGLIRAYSNMTATAIKRFGIIEVKQQIGLEITLSYPQYQLYSNLLDQLALTE
                     TETKFSDTIKTTLYCDTERVENLIDTLTNYYHGQISCEKIGSKVIEFPCD"
     gene            63013..64338
                     /locus_tag="ACF4ZO_000415"
     CDS             63013..64338
                     /locus_tag="ACF4ZO_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HFD5485993.1"
                     /translation="MESIENSYGRLLLESQLPDSAKQLAQPLKSVVILRGKMICQRCH
                     YQLDEEARLPSGAYYCRFCLVFGRNQSDKLLYAIPPMHFPKGNYLVWSGQLTAYQEII
                     SQQLLINMQNQKTTLVHAVTGSGKTEMIYAAIEAVINTGGWVCIASPRVDVCVEVATR
                     LSQAFSCSICLMHAESLPYQRAPIIVATTHQLLKFHKAFDLLIIDEVDAFPFVNNIQL
                     HYAASQALKEGGAKILLTATSTRTLERKVNKGEVVKLTLARRFHNRPLVIPKFIRSFN
                     LFKMIHRQKLPPKILKYLKKQRKTGYPLLIFLPTIIMAESVTAILKELLPAEQIACVS
                     SQSQNRKEDITAFRQGKKTILITTTILERGVTFPQIDVFVLGSHHRVYSSQSLVQIAG
                     RVGRSIDRPDGTLYFFHEGISKAMLLAKKEIKEMNYKGYSHDLSTMSTN"
     gene            64310..64975
                     /locus_tag="ACF4ZO_000416"
     CDS             64310..64975
                     /locus_tag="ACF4ZO_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HFD5485994.1"
                     /translation="MICLLCQQISQTPISITEIIFLRRISSPICQQCQKSFQKIGKSV
                     CATCCANSDIIACRDCLKWENKGYNVNHRSLYCYNAAMKAYFSQYKFQGDYLLRKVFA
                     VELADVITKYYKGYIPVPVPVSPGCFRERQFNQVSAILEAANVSYLSLFEKLDNTHQS
                     SRTKKERLLVEKSYRLLKVSNIPDKILIVDDIYTTGSTIIALRKQLAKVANSDIKSLS
                     IAR"
     gene            65055..65603
                     /gene="raiA"
                     /locus_tag="ACF4ZO_000417"
     CDS             65055..65603
                     /gene="raiA"
                     /locus_tag="ACF4ZO_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0045182 - translation regulator activity
                     [Evidence IEA];
                     GO_process: GO:0009386 - translational attenuation
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HFD5485995.1"
                     /translation="MIKFSIRGENIEVTEAIRDYVESKLTKIEKYFAKDQEIDARVNL
                     KVYRERSSKVEVTIPLDSVTLRAEDVSQDMYGSIDLVVDKIERQIRKNKTKIAKKHRE
                     KVPTGQVFTTEFEAEEVDEIPEVQVVRTKNVTLKPMDVEEARLQMELLGHDFFIYTDS
                     EDGATNILYRREDGNLGLIEAK"
BASE COUNT        20740 a        11904 c        13867 g        19794 t
ORIGIN      
        1 cgcagccagt ttgttatcgc tgatgctaaa gagcgtcaag agatgattgt ggagcaaatc
       61 aagacgcttg aagtggagca gggtgtgcaa gttgacattg acgaagactt gcttaatgaa
      121 gttttgaact tggtcgagtt tccaacagct ttcatgggaa gttttgaggc taaatacctt
      181 gatgttcccg aggaagtgct tgtgacatcg atgaaaaacc accaacgcta ttttgtggta
      241 cgtgatcaag aaggtcgttt gatgccaaac tttgtatcag ttcgtaatgg gaatgatcaa
      301 gccattgaaa atgttattaa agggaacgaa aaagttttgg tagctcgctt agaagatggt
      361 gaattcttct ggcgtgagga tcagaaattg caaattgctg atttggttgc caaattgacc
      421 aatgtgacct tccatgaaaa aatcggctct cttgctgaac acatggatcg tacgcgtgtc
      481 attgcagcat ccctcgctaa agaagccaac ctatctgctg aggaagaggc agctgttgac
      541 cgtgctgctc agatttacaa gtttgacctg ttaacaggta tggttggtga atttgatgag
      601 ctgcaaggga ttatgggtga aaaatatgct cttctatctg gtgaagatgc tgctgtggca
      661 acagcaatcc gtgaacacta cttacctgat gctgcaggag gtgcgctacc tgaaaccaaa
      721 gttggcgctg tcctggcctt ggcagataaa ttggatactc tcttgtcatt cttttctgtt
      781 ggcttgattc catctggctc taatgatcct tatgctctac gtcgtgcaac ccaagggatt
      841 gtccgtattc ttgatcattt tggatggcgc atcccaatgg ataagctggt agatagctta
      901 tatgacttgt cctttgatag tttggcctat accaataagg cggatgtgat gaactttatc
      961 cgtgctcgtg tggataagat gatgggcaaa gccgcaccaa aagacattcg ggaagctatt
     1021 ctagcaagtt caacctttgt ggttccagaa atgttagcgg tagctgaagc tcttgtcaaa
     1081 gccagccata cggaaaatta caaaccagca gttgaatctt tgtcacgtgc ttttaatttg
     1141 gcagaaaaag cggacgcttc tgttcatgtg gaccctagcc tctttgaaaa tgagcaagaa
     1201 aacactttgt ttgcagctat tcaaggcttg actctagcag gcagtgctgc ccagcagtta
     1261 gaacaggtct ttgtccttag cccagtgatt aatgatttct ttgataacac aatggttatg
     1321 gcagaagatc aagcccttaa gaacaaccgt ttagctattt tatcagattt agtaagcaaa
     1381 gctaagacca ttgctgcttt taaccaacta aacaccaagt aaatagaaag gaaagagccg
     1441 ttggggactt agctagaaaa gtgagttcag tacccgagtg gaaaaaacaa ggcctttaaa
     1501 cattgctttt cacagtgaga gtcaagtcag ttttttaagc cttatacttt tttcccaggc
     1561 tcttagtggc ttaacatgga tcctaaaaaa attgctcgta tcaatgagct ggctaaaaag
     1621 aaaaaaacgg taggcttgac tggacctgaa aaagtggaac aggcaaaact ccgtgaagaa
     1681 tacattgaag gctatcgtcg ctctgtcaga caccatattg aaggcatcaa attggtggac
     1741 gaagaaggaa acgacgtgac ccctgaaaaa ttaagacagg tgcaacgtga aaaaggcttg
     1801 cacggccgtt cattagatga cccaaaatca taagacaaaa agcagctctg aactgctttt
     1861 tgtttatcgt gatgactgtt agcttttatt ttaaatggta taatacttca aagtgaccac
     1921 acgtttttat attgtatagt caaaatatta ggaaaaacca tgtgtttgag ttataataga
     1981 agaaatcaaa gaaagaaggt agtacttatg acaattaaaa aattctctct actagccata
     2041 gccagcctct ctttactcag tcttgcagcc tgtgatatgg atgataaaga cgatcatatg
     2101 gataatcagc caaagacaag tcaaactagc aagaaagtta aactttcaga agacaaagcc
     2161 aaatcaattg cgttaaaaga tgcttctgtt acggaagctg atgctcaaat gctatcagtt
     2221 acacaagata atgaagatgg caaagccgtg tatgaaatcg agtttcaaaa taaagatcaa
     2281 gaatacagct ataccattga cgccaactca ggggatattg tggaaaaatc ttctgaacca
     2341 atcaatgact aatcaagaac tgtaatgaat aagacagcct taactcttgt gtccaattgt
     2401 ctttgcctct taggcacggc tgtttgatac cgtgttgcct ttgaggctta gttctcttta
     2461 tgacccaatg atgactctgg attagcagag tgattgttgg gtcttttgat tttctttgat
     2521 aagaaagatt acctcgttag aaatgaggag acgtggttgt catcagtgga tttttcaaga
     2581 tcatctagtg ggataagcta cctatcttat cagctttttt ttagctttaa aaattcttga
     2641 taatatattt ctgataaaat tagctataat agaatcaaat aggaaaacgc ttacttaaag
     2701 gagggtaatg aatgtcgcaa gaaaagtata tcatggctat tgatcaggga acaacaagtt
     2761 cacgagcgat tattttcaat caaaaagggg aaaaggttag cagtagccaa aaagaattcc
     2821 ctcagatttt cccacacgct ggttgggtag agcacaatgc taatcagatt tggaattcgg
     2881 ttcagtctgt tattgcgggt gcttttattg aatccagcat caaaccaagc caaattgaag
     2941 caatcggaat taccaaccaa cgtgagacca cagtggtttg ggacaaaaaa acgggtgtac
     3001 ctatttataa tgctattgtg tggcaatcac gacagacggc accaattgct gagcaactca
     3061 aacaagatgg ccatacaaaa atgatccatg aaaagacagg ccttgttatt gatgcctact
     3121 tttctgcaac caagatccgt tggattttag accatgttcc tggtgctcaa gaacgagctg
     3181 aaaaaggcga gttacttttt ggaaccattg atacttggct ggtttggaaa ctaacagatg
     3241 gtgctgttca tgtgacggat tattccaatg cggctcgtac catgctctat aatattaaag
     3301 acttaacatg ggatgatgag attttagagc ttttaaatat tccaaaagat atgcttccag
     3361 aggttaaatc caattctgaa atttatggca aaacagctgc ctttcatttt tatgggggcg
     3421 aagtgcctat ttcaggtatg gcgggtgacc aacaggcagc tttgtttggc caactagctt
     3481 ttgatcctgg tatggtgaaa aacacttatg gcacaggttc tttcattatc atgaatactg
     3541 gtgatgagat gcagttatcg agtaataatc ttttgaccac cattggttac gggattaatg
     3601 ggaaggttca ctatgccttg gaaggttcca tctttattgc aggctctgcc attcaatggt
     3661 tgcgagatgg tcttaaaatg attgagacct caccagagtc tgaacagttc gctctagcat
     3721 caactagtga cgatgaagtt tatgttgtgc ctgcttttac cggtttagga gctccttact
     3781 gggattctaa tgcgcgtgga tctgtctttg gcttgacacg tggtaccagc aaagaagact
     3841 ttgtcaaagc aaccttacaa tctatcgcct atcaagtgcg agatgttatt gataccatgc
     3901 aggtggattc aggtattgac attcaacaac tccgtgtgga tggcggtgca gccatgaata
     3961 atatgctcat gcaattccaa gctgatattt tggggattga catcgctcgt gctaaaaatt
     4021 tagaaacaac agctctaggg gcagctttct tggcagggct tgctgttggg tattgggaag
     4081 atatggatgc tttgaaggaa ttaaacgcca ctggacaact cttcaaagct agcatgaatg
     4141 aatctcgcaa ggaaaaactg tataaaggtt ggaaacgcgc tgttaaagca actcaagtgt
     4201 tcacgcaaga cgatgacgca gaataattag aggaggatgg aatggaattt tcaaaagaga
     4261 caagacgttt agctctccaa aaaatgcaag aaagagattt agacctacta attattgggg
     4321 gaggtattac gggtgctggt gtggcgcttc aagcggcagc tagtggccta gatactggtc
     4381 tgattgagat gcaagatttt gcggaaggaa cctccagtcg gtcgaccaaa ttggttcatg
     4441 ggggacttcg ttacttgaaa cagtttgacg ttgaagtcgt ctcagatact gtttcagaac
     4501 gtgctgtggt ccaacagatt gcacctcata ttcctaagcc agatcctatg ttattacctg
     4561 tttatgacga acctggcagc acctttagca tgttccgttt gaaggtcgct atggatttgt
     4621 atgatctttt agcaggcgtg tccaatacgc cagcggccaa caaggtgtta accaaagaag
     4681 aagtcttaaa acgagaacca gacttaaaac aagaaggctt gcttggtggt ggcgtttacc
     4741 ttgatttccg caataatgat gcaaggcttg ttattgagaa tattaagcgt gctaatcgtg
     4801 atggggctct tattgccagc cacgtgaagg cagaagattt cttgctagat gataaaaggc
     4861 agattatcgg cgttaaggcg cgtgatttat taacagatca agaaattatc atcaaggcta
     4921 aattggtcat caataccaca gggccatgga gtgatgagat tcgtcaattc tctcataagg
     4981 gacaaccgat tcatcaaatg cgtcctacaa aaggagtgca tttggtagtg gaccgtcaaa
     5041 aattaccggt gtctcaacct gtctatgttg acacagggtt aaatgacggc cgtatggttt
     5101 ttgtcttgcc acgtgaagaa aaaacttatt ttgggacaac cgatacagac tacactggag
     5161 acttgcagca cccacaagtt acccaagaag atgtggatta tttgttaggg attgtcaata
     5221 accgcttccc aaatgccaac ttgactatta atgatattga aagtagttgg gctggtcttc
     5281 gtcccttgtt gtcaggcaat agtgcctctg actacaatgg tggcaatagt ggtaaactca
     5341 gcgatgacag ttttgaccac ttaattgata ccgttaaagc ctatattaac catgaagata
     5401 gtcgagaagc cgtcgagaaa gccattaaac aggtagaaac cagtacttct gaaaaagaat
     5461 tggatccgtc agcggtatct cgtggttcca gttttgagcg tgacgagaac ggcctcttta
     5521 ccttagcagg tggtaagatt acggactacc gtaagatggc cgaaggtgct ttgaaagtca
     5581 ttatccaagt cttgaaagaa gatttcggca aatcgtttaa gcttatcaat tcaaccacct
     5641 atccagtttc tggcggtgaa attaacccag ccaatgtgga ttcagaattg gaagcctatg
     5701 cgcaattagg cacccttagt ggactgtcca tggacgatgc taggtatttg gctaatctgt
     5761 atgggtctaa tgcaccaaaa gtctttgcct taactcgtca attaaaggcc gctgaaggat
     5821 tgagtttagc agaaacgtta tctttacact atgcgatgga ttatgaaatg gctcttaaac
     5881 caacggatta tttcctaaga agaaccaatc acctcttgtt tatgcgagat agtctagatg
     5941 ctttaatagt gccagttatt gaggaaatgg ctaaacactt tgactggtca actgatgaaa
     6001 aagttaagca ggaagaagag cttcgtcgtg tgattgcaga aaatgatttg agtgccctaa
     6061 aaggccagca ggaggactaa tatggatatt tttggcgaat ttttgggtac agccttattg
     6121 gttttactag gaaatggtgt ggtagcaggg gttgtcttgc ccaaaacgaa aacccatgct
     6181 tctggctgga tcgtgattgc gactggctgg ggaattgcag ttgctgtggc agtctttatc
     6241 agtggcaaaa ttgcccctgc ccacctcaat ccagctgtta gccttgcttt tgccatgagt
     6301 ggaaccattg cctggtcaac agccattgcc tatagccttg cccaactatt gggagctatg
     6361 cttggttcaa ctctggtatt ccttcagttc aggccacatt atctggctgc tgagagtcag
     6421 gctgatattt tagggacatt tgcgacaggt cctgctattc gagataccag ctcaaaccta
     6481 ttgagtgaaa tctttgggac ctttgtcttg atgcttggta ttttggcatt tggcttatat
     6541 gatatgccag caggactagg aaccctctgt gtaggtacct tggttattgg gattgggtta
     6601 tccttaggag gaacgacagg ttacgccatt aacccagcgc gtgatttagg acctcgtcta
     6661 gttcatgcta ttctaccact caacaacaag ggagattctg attggtctta tgcttggata
     6721 cctgttgtag gaccaattat tggagcggcc ttagcagttt tgcttttcca agtcatgtcc
     6781 taaccatcac taaaggggtt ggctatcata ggccagctcc tttgcttttt ctttatagga
     6841 ttaggtaaaa cgctttcata tcttaaaaac aactgctata ataatactat tatgacatta
     6901 acgacaaaga ccatacatgt tatcggggca tcctttgctg gtctagcctt tgttgataaa
     6961 tataaggacc tcaatccaga ttcccaaatc attctcattg ataaggaaag ctgtcccaat
     7021 tatattccaa atggtatcaa ccaattattc agaggagaca ttcaagacct gtctgatgct
     7081 atgtggggaa gagcctgcct agcagcacaa atagaatcta accaccggtt tattcaagca
     7141 gaagtgttag ctatcgaagc tccctcaaac accttgcttc tcaaagacag tcaaggacga
     7201 gtttttgaag aaggttatga aacgcttgtt tgtgccatgg gtgctagccc ccagtctcat
     7261 tatattgaga cgtcacagac caacaaagtt ttggtaacaa aatattatga agaaagccaa
     7321 gctagtttaa aactgattga ggctagccaa gaggtcttgg ttattggtgc cggcttgatt
     7381 ggcttagacc ttgcctacag tttgtcctta caaggcaaac gggtcaaact gattgaagca
     7441 gccgaacgtc cagatttcta tcagactgac gcagaactga tagcccctgt aatggcagaa
     7501 atgtccactc accatgtcac ctttattaat aataagcgtg ttacggctat tcatgagata
     7561 gagggaaaag ttgtcgctca taccgagcaa ggggacacct tccaaggtga tttggctatt
     7621 ttagccatta actttaggcc aaatacacac cttttgcaag gacaagtggc ttgtgctctg
     7681 gataagacca ttttggttaa tgaaaactta cagaccagcc aggctaatat ctatgccatt
     7741 ggagacatgg tttcattgca ttttggtata ttgggaatgg attactatac acctttgatt
     7801 aaccaagcaa tgaagacagg tcaggctctg gctctgcatt tagctggata tcctattcct
     7861 ccattacaga cggtcaaggt attaggaagt tctcactttg gttattatcg cgcgagtgtt
     7921 ggtgtgacag aagaagaagc agagctttat atggatacgt gtagctattt gtaccaaaat
     7981 ggggattcca aaaacctctt ttggctgaaa ttaatagcta gaaaaacgga tgggatttta
     8041 ataggcgctc agctcctatc caaaaccaat gctcttgtca tcgccaatca attaggtcag
     8101 gctctggctc tgaaagttac agacgctgac ttagcatttc aagattttct ctttttacaa
     8161 ggtcacagtg atttggctta tcatcttcat gaagcttgtc tcaaattatt tgaaaagagg
     8221 ctccgccatg aagattgaag acttaatgga taaggaacga agggcccaat atcgtctctt
     8281 ggtgaccctt tatcatgcta aagaaacgtt aaggctaaaa gacctaatga ggctatcaaa
     8341 cttgtctaaa gtgaccctat taaaatacat tgacaaccta aatcatttgt gtcgagaaca
     8401 aggtttagcc tgtcaattac ttttagaaaa agacagtctg agcttaaaag aaaatggcca
     8461 attccattgg gaggatttgg tagctctgct tctcaaagaa tcggttgcct atcagatatt
     8521 gacctacatg tactgccatg aacactttaa catcaccaac ttatccgttg aactgatggt
     8581 tagtgaagct actctaaaca gacaactagc tcacctcaat cagcttttat cagaatttga
     8641 tctggcgctc tcgcaaggca gacaactggg aagtgagctt cagtggcgtt atttctattt
     8701 tgaattgttc cgccatacct tgaccagaca aggcagagac gccttggtca atcagttaga
     8761 cgcttcgcat ttggctacct taattgagcg gctgattggc cagtcattat cggcagaagc
     8821 cttagaacaa ttattgattt ggttggcgat ttcgcaagcg cgaatgtcct ttcaaaaagg
     8881 ctacaatgat cattttttaa gagatagtga ctttatgaca tctaatattt tctttaagcg
     8941 cttagaaagc atgcttttac gttacttaag acgctatgcc cttgaatttg atgcttttga
     9001 agctaagagc ctctttgtct ttttgcatgc ttatcctcta cttcctattg ccagcatgaa
     9061 gtatagtttg ggttttggag gtcctattgc tgatcacatt tcagaagcct tatggctttt
     9121 aaagaaggct catgtgatta tccatcagac aaaggaggaa atcatctatg gcttggggat
     9181 atttttttcc aaagcttact tttttaaagg agctatcctt agtcaaccaa ccaatagcca
     9241 atacctttat caattagtag gcgaagataa aagagcgctt ttaagggtta tcataaacca
     9301 tttagtgctg caaatggatc aggaaacgga tttcagtcag cagttgagtg acgacatttt
     9361 agcattgttg attttttcca ttgagcgcca ccatgagcct cttttagtag ggcttgcctt
     9421 ggggcaaaat aaggtggaag cagccattgc ggaattggcc attagacgtc atttggggca
     9481 tcgtagggat tttcaattaa tgccctatga tcatcagaaa gtttatgact gtctgattac
     9541 ctatcagact gtctgtttac cgagacaaga tttaccctat taccggttaa aacaatatag
     9601 ctccccctac gaactcactg ctttagaagc ttttctcaaa gaccttttcc agcaaaaaaa
     9661 tacacgagaa gaggaactct cactcagccc agcagctaag tctagttttg cacacaaaat
     9721 tgtgtgatac ttggtctttt ctaagtactg ttacactttt ataataataa agtaggatag
     9781 tctaaaggta gatgatttga aaaagcttat caaatagagc ttaacaaaat cgaaaatttt
     9841 tggaggtaag aaatgaaatt tttcctagat acagctaatg tagccgctat taaagcgatt
     9901 aatgaacttg gcgttgtaga tggtgtcacc accaatccaa ccattatctc acgtgaagga
     9961 cgtgattttg aaacagttat caaagaaatc tgtgacatcg tcgatggtcc aatcagtgct
    10021 gaagtgacag gattaacagc agatgctatg gtagaagaag ctagaagcat tgctaagtgg
    10081 catgacaatg tcgtcgttaa aattccaatg accacagaag ggttaaaagc aacaaacatt
    10141 ctttcaaaag aagggattaa aactaatgtg accttgattt tcacagtaag ccaaggttta
    10201 atggcaatga aagcaggcgc aacttacatt agcccattta tcggtcgttt ggaagatatt
    10261 ggcacagatg cttatcaatt aatcagcgac cttcgtgaaa tcattgactt gtacgatttc
    10321 caagcagaaa tcatcgcagc aagtattcgt acaacagccc atgtggaagc tgttgctaaa
    10381 ttaggcgcac acattgcgac gattccagac cccttgtttg ctaagatgac gcaacatccc
    10441 ttaacgacaa atggtttgaa aacctttatg gaagattggg cttcctttaa aaaataaggc
    10501 taaagagtct gtggctactg tgtcaacagg ctctcttata ttcatcgtca aaaagaattc
    10561 accaatgatg tccaaactag tttttttctg gcaaaatagg gaaaaagaat ttagggactt
    10621 tggaggattt tctgaaaaaa gcgtctattt ttgtgataca atagacaata gaaaacgttt
    10681 aattttagtt gtaataaaca gagaggtttt acttatgaca tttgatgcaa ttgaccaatt
    10741 ggcagtaaac actgtccgca ccctatcaat ggatgccatt caagcggcaa attctggaca
    10801 cccaggactt ccaatggggg cagcacctat ggcctatgtt ctttggaatc acttcatgaa
    10861 catcaatccc aaaacaagcc gtaattggtc aaacagagac cgttttatcc tatcagcagg
    10921 tcatggaagt gccatgcttt atagcttgtt gcatttagca ggttatgatt tatctgtaga
    10981 agatttaaag aacttccgtc aatggggatc taaaacacca ggtcacccag aagtgaacca
    11041 cacagacggt gtcgaagcaa ccacaggacc tcttggtcaa gggatcgcaa atgccgttgg
    11101 tatggccatg gcagaagctc acctagcagc taaatttaac aaaccaggct ttgacatcgt
    11161 tgatcactac acatttgctt tgaatggtga cggtgacctt atggaagggg tcagccaaga
    11221 agcagcaagt atggcaggac atttaaaact tgggaaattg gtcttgctat atgattcaaa
    11281 cgacatctct cttgatggtc caacctctat ggcttttaca gaagatgtga aaggacgttt
    11341 cgaagcttat ggttggcaac atatccttgt gaaagatgga aatgatttag aagaaattgc
    11401 agctgctatt gaagcagcta aagctgaaac tgagaaacca accatcatcg aagtcaaaac
    11461 cattattggt tttggtgccg aaaaacaagg aacttcagct gttcacggcg ctcctcttgg
    11521 agcagaaggc attgcttttg ccaaaaaagc ttaccaatgg actcatcaag attttgaagt
    11581 gcctgctgaa gtaacagagc gctttgctca aggtcttcaa gcgcgtggtg aaaaagcaga
    11641 acaagcctgg aatgacttgt ttgcagctta tgaagcagaa tatccagaat tagcagcaga
    11701 ataccaaaaa gcctttgcta acgaagctgc tcaagtagaa cttgaagcgc acgaacttgg
    11761 tagttcaatg gcgagtcgtg tatccagtca acaagccatc caacaaattt cagaacaagt
    11821 agcctctttc tggggtgggt cagcagacct ttcagcttca aacaatacta tggttaaggc
    11881 tgaaacagat ttccaaccag gtcactatga aggccgtaac gtctggtttg gcgttcgtga
    11941 atttgccatg gctgcagcta tgaatggtat tgcccttcac ggcgggacac gcgtttacgg
    12001 tggaaccttc tttgtctttt caaactacct tcttccagct gttcgtatgg cagcgctcca
    12061 aaacttgcca acagtttatg tcatgacaca tgattctatc gctgtcggtg aagatgggcc
    12121 aacgcacgaa ccaattgaac aattggcaag tgttcgttca atgcctaact tgaacgttat
    12181 tcgtccagca gacggtaacg aaacaaatgc tgcttggaaa cgtgccattg ctgaaacaga
    12241 tcgcccaacc atgcttgtat tgacgcgtca aaaccttcca gtgcttgagg gcacaaaaga
    12301 attggcagaa gatggtctta acaaaggagc ttacatcttg tcagaagcca aaggcgacct
    12361 tgaaggtatc ttgattgcaa caggttcaga agtgaaactg gcaatggata ctcaagaagc
    12421 tcttgaagca gaaggcattc atgtgcgtgt ggtatctatg ccatcacaaa atatctttga
    12481 cgaacagtca gcagagtata aagaaagcat cctaccagca gctgtgacta aacgtctcgc
    12541 tatcgaagca ggttcaagct ttggctgggc aaaatatgtc ggcctagcag gaaaaacatt
    12601 gaccattgac acttggggtg cttcagctcc aggaaatcgt atcttcgaag aatatggttt
    12661 cactgtggca aatgcaactg agttatacaa atcactctag gttacacatc ccaaacagag
    12721 taaatcaaat gatttactct gtttttttaa aataaaatac ccagttcttt cttttcctca
    12781 aactgcctaa tacacttctt ttgataagaa gtcattgaca aaacaattca taaaaattat
    12841 aatttaattg ttattgtatt agcgtaaaag tacaaaaata aaggagtata aatggaaaag
    12901 aaacgacagc gcttatacga tgtgattaga cacgcttatg attatccaga aaatcgtgaa
    12961 aatgtggcct tgtcgcagct acttttagca gcttctaata gattaattaa acacagtaac
    13021 ccacttcttg ttgcctacca actaaaccaa gatgtggata attacttact tgataatgac
    13081 attttacttc caaaatcgct ttgccgtttt aagcagtcat tggaaaagta tattttagag
    13141 gaagcctcat cagtctaggg agaaaaagag aagaaaagga aaaaggatac catgatagaa
    13201 tttaaacacg tttcaaagtt gtatggcgac aaagaagctc ttagcgattt aaacgtcacc
    13261 atcaatgacg gtgaaatttt tggcctcatc ggacataatg gtgcaggtaa aaccacgacc
    13321 atcagcattt tgacttctat tatcgaagcg agttatggag aagtatttgt ggatggtcaa
    13381 cttctgacag aaaatagaga agctatcaaa aaacaaattg cttatgtgcc agattctcct
    13441 gatattttct tgaatctaac tccaaatgag tattggcagt ttttagctaa aatttatggg
    13501 gtgtcagatg aggacagaga agaacggtta gcacagctaa caacactttt tgaactaaag
    13561 gaagaaggta atcaaaccat tgatagtttc tcacatggga tgcgccaaaa agtgattgtg
    13621 attggtgctc ttgtatcaaa tcctaacatc tggattttgg atgaaccatt aacaggtttg
    13681 gatcctcagg cttcttttga ccttaaggaa atgatgaaag ctcatgcagc ttctggacat
    13741 acggtcttat tttcgactca cgtgctatca gtcgctgagc agttatgtga tcgtatcggg
    13801 attctaaaaa aagggaaatt gatttttgtt ggaacgattg atgagttaaa agaacaccat
    13861 cctgacaaag atttggagag catctacctt gaactcgcag ggcgtaaggc gcaagaagag
    13921 gggtgatggg atgaattggt ctactatttg ggaacttatc aagataaaca ttctttattc
    13981 caatccacaa agtttagcta acctcaaaaa gcgtcaggaa aaccacccga aagaaaactt
    14041 caaagcctat aaaagcatga tgaggcaaca ggccttaatg attgccatgt ttttggtgat
    14101 ttaccttttt atgtttattg gtgtcgattt cagtcattat ccaggacttt tctcctttga
    14161 cgttgctatg ttttttatca tgtcaacctt gacagccttt agctctcttt acaccatttt
    14221 ttatgaaagt aatgacttaa aactttatat tcacttacca gtaacgtcag aagaactcta
    14281 tattgcaaaa attgtctcgt cgctagggat gggtgctgtc tttttgatgc ctcttatctc
    14341 tcttctctta attgcctatt ggcaactatt gggaaatcct ttgtctattt tagtagctat
    14401 tgtgctcttt ttagtgttac tagtgagttc gatggtatta gctatttata tcaatgcttg
    14461 ggtgggcaaa atcattgtaa ggagtcgcaa gcggaaactc atttcaacta tcatgatgtt
    14521 tgtctcaact tttggagctt tcgtcttaat ttttgcgatt aatattagta acaacaagcg
    14581 tacgatgacg gatggcgtat ttactgatta cccaactatt ccgtatttca aaggattcta
    14641 tgatgttatt caggcaccgt tttctactgc ggccctcctt aacttttggt tgccattgct
    14701 actgatttta gctatggtat atggtattgt cacaaaagtg atgccaactt attatcgtga
    14761 ggctttttat attagtaacg agaacaaagc caagcaaact aaaaaaccag ttaatcgtcc
    14821 tcatcagaat caatcactga cgcagttgtt gcgaaaacat catcttttaa cgttacaaaa
    14881 tgcaacttta ctgacacaaa cctatctcat gcccctgatg tatgtgatgc tttttatcgg
    14941 tccaagtttg tcacgtggca caggtttctt taagcatatt tccccagatt actttggggt
    15001 ggccttatta tttggggtca gtttgggtgt catgtgtgca acaccaacca gctttattgg
    15061 agtaggtatt tcacttgaaa aggataactt tacctttatt aaaagcttac caataacgtt
    15121 aaaaaaattc ttgctggata aattttgctt gctcgtcggt ctgcaactga ttgtgcctat
    15181 ggtgatttat cttgtgtttg gtctctttgt gttgcacctg catcctcttc taacgattgc
    15241 tttttgtctt ggctacgccc tgtctctgat tgtgcaaggg gaattgatgt atcgtcgtga
    15301 ctaccggctt ctggatttaa aatggcaaga catgacacaa ctctttacca gaggaaatgg
    15361 gcagtggcta acaatgggcc ttatctttgg taatttaata gtcacaggtg tagtaggttt
    15421 tggagctgtt atcattgcca atattatcca acaacctctg ttgattagta ttctattgag
    15481 ttgtctgaca ctaatggttt tagggattgc tcacttatgg attcaaaaaa ccttctggaa
    15541 aagcttagag aagctttaac gaagagagat cattattcgg aaaaacagtc ctctggggct
    15601 gtttttatgc tataatttgg gtatgatgaa acgacaattt gaagatgtaa cacgtatcgt
    15661 aattaaaatt ggcactagtt cattagtgct accaacaggt aaaatcaatt tagaaaaaat
    15721 cgaccaactg gcttttgtga tttcaagttt gatgaataag ggcaaggaag ttattttagt
    15781 atcatcggga gcgatgggat ttggactaga tattttgaaa atggaaaaac gtccgaccaa
    15841 tcttgctaaa caacaggcag tttccagtgt tggtcaggtg gccatgatga gtctttattc
    15901 acaaattttt gcacactacc aaaccaacgt gtcacaaatt ttattgacga gagatgtggt
    15961 ggttttccca gaaagtctag ccaatgttac caatgctttt gaaagtctga ttagtttggg
    16021 cattgtgccg attgttaatg aaaacgatgc ggttagtgtg gatgaaatgg atcatgcgac
    16081 taaatttgga gataatgacc gtttatctgc tgtcgttgct ggtattacaa aagctgattt
    16141 attaatcatg ttgtctgata ttgatggcct ttttgataaa aaccctacta tttatgagga
    16201 tgcgcagtta cgcagtcatg ttgcagtcat tacgcaagaa atcattgcgt cagcaggtgg
    16261 tgcgggcagt aaatttggca caggtgggat gctaagtaag gtgcagtctg ctcagatggt
    16321 atttgaaaac aaaggacaga tggtcttgat gaatggagct aatcccagag atgttttaag
    16381 agtgcttgaa gggcaaccac taggcacctg gttcaagcag atagaagagg taacacatga
    16441 ctgatatgag aaggttaggg caaagggcaa aacaagctag tcttttaata gcacctttgt
    16501 cgacgcaaat taaaaatcgc tttttaagca ccttagcaaa ggcattagtt gacgatacac
    16561 agactctctt agccgctaac caaaaagatt tagcgaatgc taaagaacat ggtatttctg
    16621 acatcatgat ggatcgcttg cgcttaactt cagaacggat taaagcgata gcacagggag
    16681 ttcaacaggt tgctgactta gctgatccaa tcggacaagt cattaagggc tatactaacc
    16741 tcgatggtct taaaatcctc caaaagagag ttcctctagg ggtgattgcg atgatttttg
    16801 agagtcgccc gaatgtttca gtggatgctt ttagtctggc gttcaaaacc aataatgcga
    16861 tcatcctaag gggaggaaaa gatgcccttc actcaaataa agctttggtg aagttgatcc
    16921 gacaaagtct ggaaaaatca gggatcaccc cagatgctgt ccagctagtt gaggatccct
    16981 cacatgctgt cgctgaagaa ttgatgcagg caacggatta tgtagatgtt ttgattccac
    17041 gtggtggtgc taaattaatt cagaccgtta aggaaaaagc aaaagtgcct gtcatcgaaa
    17101 caggtgtggg gaatgtgcat atctatgtgg atgctcaagc tgacttagat atggctacta
    17161 atattgttat caacgctaaa acaaagcgcc caagtgtttg caatgcagct gagggattgg
    17221 taattcacga agctgtagca gcaaggttta ttcctatgct tgaaaaagcg atcaatcagg
    17281 ttcagccagt agaatggcgg gcagatgaca aggctttgcc gttatttgag caggcagtgc
    17341 ctgcaaaagc agaggatttt gagaccgaat ttttagatta tatcatgtct gttaaggttg
    17401 tttcctcttt ggaagaagct atttcttgga taaatcagca tactagtcac cattccgaag
    17461 ctatcatcac aagggatatt aaggcagcag agacctttca agatttagtg gatgctgctg
    17521 ctgtttatgt caatgcttca acacgattta ccgatggttt tgtttttggg cttggtgctg
    17581 aaattgggat ttctactcaa aaaatgcacg cccgtgggcc aatgggctta gaagccttga
    17641 ccagcactaa attttatatt aatggggatg gacatatcag agaataagct actagaaggt
    17701 cccttaatga ctaatgaaag agaaaaagaa gaagcaaagg ttgctttaga agaactttta
    17761 catcagattc aggtgattca tttggaattg aaaattgtcc gaaattgggg ctattttgat
    17821 ctttttggag acggtatgct tgtcagctgg atcaaacgtc gaaaaatgag caaggtcaac
    17881 caattattaa tagacttaca agttactctt caaaactgcc gaagatagtt ggcaaacgtc
    17941 gataggctat tattagctga cttaccgaat atgagttggg ataaaacctt tgatatttgg
    18001 ttagacaacc tgctgacaga ttgttgtgtg attaaagaag ctaaaaattt tttacaagca
    18061 gttgaaattc tagaggcagc ggctaagtca gtgcttgcta agttggctga tagcgaacaa
    18121 aaagaacaag attagagaag aggaagattc ccacgagaat gaaatccttt tctcttactt
    18181 tttcatttct aaaccttttg aagtatggta caattaaagt tatgacaaaa gaatttcatc
    18241 acgtgaccgt actccttcac gaaacagtgg acatgcttga cataaagcct gatgggattt
    18301 atgttgatgc gacgctaggt ggctcaggcc actcagctta tttgttgtcc aaacttggtg
    18361 aagaagggca cctctattgt tttgaccaag accaaaaggc tattgacaat gcacaagtta
    18421 ccctcaaatc ttatattgac aaaggacagg taacttttat taaagataat tttagacacc
    18481 tcaaagcacg tttaacagcg cttggagttg atgaaattga tggtatctta tacgaccttg
    18541 gtgtttccag cccgcaattg gatgaaagag aacgagggtt ttcttataaa caagatgctc
    18601 cattggatat gcgcatggat cgtcagtcgc tcttaacagc ttacgaagtg gtgaatacct
    18661 atccattcaa tgatttggtt aagattttct tcaaatatgg tgaagataaa ttctccaagc
    18721 agattgctcg aaaaattgaa caagcaagag ctattaagcc tattgagaca acaacagagt
    18781 tggcagaatt gattaaggca gcaaagccag ctaaagagtt gaagaaaaaa ggccaccctg
    18841 ctaaacagat ttttcaagct attcgcattg aagtcaatga tgaattggga gcggccgatg
    18901 aatctattca ggaagctatg gaattattag cccttgatgg tcgtatctca gtcattacct
    18961 tccattctct ggaagatcgc ctaaccaagc agttgtttaa agaagctagt acggtggatg
    19021 tgccaaaagg gcttcctcta attcctgaag atatgaaacc taagtttgaa cttgtttcac
    19081 gtaagccgat cttacctagt cattcagagt tagcagctaa taaaagggca cactcagcca
    19141 agctacgtgt tgccaaaaaa attcggaaat aagcctatga caaatgaaaa aagaactcag
    19201 gcagttacaa atgccttgca aaaacgaata aaaactttct ctagaattga gaaggctttt
    19261 tatactgcta tcattgtaac agcgattacg atggcagtaa gtattattta cctgcaaagt
    19321 cgtaagttgc agctacaaca agaaatcact agtttaaata gtcatatttc ggatcaaaaa
    19381 ctagagctta ataatgccaa gcaagaagta aatgagttat ctcgccgtga tcgtattata
    19441 gatattgctg gtaaagcagg cttaagcaac cgtaataata atatcaagaa agtcgagtaa
    19501 tctatgaaaa aatggcaaaa atatgtttta gattatgttg tgcgcgatag gagaactcca
    19561 gtcgaaaatc gcgttcgagt tggacaaaat atgatgctct taactatctt tattttcttt
    19621 attttcatta ttaatttcat gattattatt ggaacagatc aaaagtttgg agttagtttg
    19681 tcagaagggg cgaagaaggt ttatcaagaa accgttacga tccaagctaa gcgtgggacc
    19741 atttatgatc gaaatggtac agctattgca gtggattcta cgacttatag catatacgca
    19801 attttggata aatcatttgt ctcggcttca gatgaaaagt tatatgtaca accttctcag
    19861 tatgaaacag tagctgatat tttaaaaaag catctgggaa tgaaaaaaac agatgtaatt
    19921 aaacagctta agcgtaaagg acttttccaa gtctcgtttg gaccgtcagg gtctggcatt
    19981 tcatatagta ctatgtctac tattcaaaag gctatggaag atgccaaaat caagggaatt
    20041 gctttcacaa ctagtcctgg tcgtatgtat ccaaacggga catttgcttc agaatttata
    20101 ggcttagcat ctctaacaga agataaaaag acaggtgtta agagtttagt tggaaaaaca
    20161 ggtctagaag cttcttttga taaaatttta tcaggtcaag atggtgttat tacttatcaa
    20221 aaagatcgaa atgggaccac actcttgggt acaggtaaga ctgtcaagaa agctattgat
    20281 ggcaaagata tttacacaac gctatctgag cctatccaga ccttcttaga aacccagatg
    20341 gatgtttttc aagccaaatc aaatggtcag ttggccagtg caacacttgt taatgctaaa
    20401 actggtgaaa ttttggcaac aacacaacgc cccacttata atgctgatac tctgaaagga
    20461 cttgaaaata cgaactacaa atggtacagt gcacttcatc aaggaaattt tgagccaggc
    20521 tcaaccatga aagtgatgac tctggcagcg gctattgatg ataaagtttt caacccaaac
    20581 gaaaccttta gcaatgctaa tggtttaaca attgcagatg ctactattca agactggtct
    20641 attaatgaag gcatttccac aggacagtac atgaattatg cacaaggatt tgccttctca
    20701 agtaacgttg ggatgactaa acttgaacaa aaaatgggta atgcaaaatg gatgaattat
    20761 ttgacgaagt tccgctttgg ttttcctact cgttttggtt taaaagatga agacgcaggt
    20821 atatttcctt ctgataatat cgtgactcaa gctatgagcg cttttggtca agggatttct
    20881 gtaacccaga ttcaaatgct tagagccttt actgctattt ctaataatgg tgagatgtta
    20941 gagccacaat ttatcagtca aatttatgat cctaacacag caagttttag aacggcaaat
    21001 aaagaagttg ttggaaaacc tgtatcaaaa aaagccgcta gtgaaacaag acaatacatg
    21061 attggtgtag gaacagaccc tgagtttgga acactctatt caaaaacatt tggaccaatt
    21121 attaaagtgg gtgatttacc tgttgctgtt aaatcaggaa cagcacaaat tggttcagaa
    21181 gatggaagtg gttatcaaga tggtggattg actaactatg tctattcggt tgtggcaatg
    21241 gtgccagctg ataaaccaga ctttttgatg tatgttacta tgactaaacc acaacatttt
    21301 ggtccccttt tttggcaaga tgtggttaac ccagtattgg aagaagcata cttaatgcaa
    21361 gatacactaa ctaagccagt agtatcagat gctaatcgtc aaacaactta taaattacca
    21421 aactttgtag gaaagaatcc tggtgagaca tcaagcgagt tgcgtcgaaa tcttgtccag
    21481 ccagttgtcc ttggtactgg cagcaagatc aaaaaagtat cgcatcagtc cggtcaaaca
    21541 ttaacagaaa accaacaagt tctcatatta tcagaccgtt ttgtggaggt accagacatg
    21601 tatggctgga caaaatccaa tgttgaaacc tttgctaaat ggactgggat agacatcagc
    21661 tttaaaggaa cagattctgg tcgtgttatg aaacaaagtg ttgatgttgg taagtccttg
    21721 aaaaaaataa aaaaaatgac cattacttta ggagattaac atgtttttaa cccttattgc
    21781 agcaatcata tcctttatgg tatctgcttt cacaatgcct tattttatca aattctatca
    21841 attgaaaaaa attggtgggc aacaaatgca tgaagatgtc aagcaacatt tagctaaagc
    21901 tggaacaccg actatggggg gaactgtttt tcttttagta gctacggcag tatcgttatt
    21961 ggttagtcta ttttcgatca aaaacactca aagtttagct ttgatttcag gcattttatc
    22021 aattgttgtc atttacggga ttatcggatt tttggatgat tttttaaaaa tttttaagca
    22081 aatcaatgaa ggattgacag ccaaacaaaa attagccttg cagttggctg gaggattgat
    22141 gttctatttt ttacatgtta gtccaagtgg catttcttcg atcaatgtgt ttggttatca
    22201 gctgtcgctg ggaattttct acctattctt tgttctattc tgggtggttg gtttctcaaa
    22261 tgccgttaat ttgacggatg gtatcgatgg cttagcttct atctcagtgg tgattagttt
    22321 agtgacttac ggcgttattg cctacgttca ggggcaattt gatgtcttat tattgattgg
    22381 aaccatgatt ggtgctttac ttggtttctt cctatttaac cacaagcctg ccaaagtatt
    22441 tatgggagat gtggggagtt tggccttggg agctatgttg gcagctattt ccattgccct
    22501 gcgtcaagaa tggaccttac tcattatcgg aattgtctac gttcttgaaa caagttctgt
    22561 gatgttgcaa gtgtcctatt tcaagtacac caagaaaaaa tatggagaag gtcgtcgtat
    22621 ttttagaatg acgcctttcc accaccattt ggaattggga ggcttgtctg gtaaaggcaa
    22681 gaagtggtca gaatggcagg tagatgcttt tttgtgggga gtaggaagtc tagctagttt
    22741 actagtttta gctatcttat acgtcttcta agggggatta tcaagaatag tcaccaatag
    22801 cattttgatt aacatcatca ataagagagt ggagatgacc cacaaatgct gattttgtga
    22861 gtgttgtccc actccttttg cttgtctcta ataataatga tataatatgg aagaaaacga
    22921 ggtaaaacat gtcatttaaa gattatcatt ttaagcaata cgttcagcaa gcgctggaag
    22981 aaattggctt tgtcaatcca acagaggtcc agcaacgctt gattcctatt gttaactccg
    23041 gtcgtgactt agttggggaa tcaaaaacag gttcagggaa aacccacacc tttttgttgc
    23101 ccatttttga aaaacttgat gaagctaaag cagaagtgca agtcgttatt acagcaccta
    23161 gccgtgaatt agcaactcaa atttttgatg cttgtaaaca gattgctaag cactcccaag
    23221 aagagattcg tttggccaac tatgttggag gcacagacaa actccgtcag attgaaaaac
    23281 taaaaggcag ccagccgcat attgtcatcg ggaccccagg tcgtatttat gacttggtca
    23341 agtctggtga tttagcgatt cataaagcaa cgacctttgt tgttgatgag gccgatatga
    23401 ccatggacat gggctttttg gatacggtag ataagattgc agcttcgctt ccaaaatctg
    23461 ttcagatttt ggtgttctca gcaactattc cacagaaatt acaacccttt ttgaaaaaat
    23521 acttgaccaa tcctgttatt gaacaaatca agacaaagac cgttatcgca gataccattg
    23581 ataactggct tgtgtcgaca aaagggcgtg ataagaatgg tcaactgtta gagattctca
    23641 aaaccatgca gccttatatg gctatgcttt ttgtcaatac caaggaacgc gcagatgatt
    23701 tgcatgcctt tttaacagct aatggcttaa aagtggctaa gattcatggg ggcattcctc
    23761 caagagaacg taagcgcatc atgaaccaag tcaaaaaact ggactttgaa tacattgttg
    23821 ccacagactt agcagcgcgt gggattgaca ttgaaggggt cagccatgtg atcaatgacg
    23881 ccatcccaca agacttgtct ttctttgtcc atcgtgtagg ccgaacaggt cgaaatggta
    23941 tggcaggaac tgccattaca ctttaccagc caagtgacga ctcagatatc aaagagctgg
    24001 aaaaaatggg gattgccttt acaccgaagg tgctcaaaaa tggagaattt caagatacct
    24061 atgaccgtga tcgccgtcaa aaccgtgaaa aagcctatca aaaattagac acagaaatga
    24121 ttggtttggt caaaaagaaa aagaaaaaag tcaaaccagg ttacaagaaa aaaattcagt
    24181 gggcggttga tgaaaaacgt cgcaaagaac gtcgtgctga aaatcgtgct aagggtcgcg
    24241 ctgagcgtaa ggccaaaaaa caacattttt aagaacaaag agcaagcaag tgatcaattg
    24301 gcatctaatc ttgctttttt tacacctgct acttgtattg tttaccattt gttagcacaa
    24361 aaagtgatca tagcttttgc ttattgctat aatacggatt tactatttta catgtgggtc
    24421 taagagtgtt agaatattaa gacaaacaaa tacaaagggg aaatacatga catcagtgtt
    24481 tttaaccagt ggttgggctt tttatgatca tctcatctca ccgattccac atgggaaact
    24541 ttttagttgg catgctgttt ttgatgccat tccaaatatt atccaacggc ttccaattac
    24601 gcttggtttg acactatcag gagcaacctt tggcttggtt ttggctttga tttttgccct
    24661 tgtcaaaatt aataaagtga agctactata ccctattcaa gctatttttg tgagtttctt
    24721 gcgaggaact cctattttgg tacagttgat gttgacctac tacggtattc ccctctttct
    24781 aaaatttctc aatcagaagt atggctttga ttggaatgtt aatgcaattc cggcttctat
    24841 ttttgccatt acagcctttg cttttaatga agcagcctac gctagtgaaa ctattcgggc
    24901 agccatttta tcagtagata caggtgaaat tgaagcagca aaaagtctag gcatgacttc
    24961 tgtgcaggtt taccgtcgtg tcattattcc taatgcaact gttgtggcta ttccaacctt
    25021 gattaatggg ttaattggct taactaaagg aacatcgctt gcctttaatg cagggattgt
    25081 cgaaatgttt gcccaggctc aaattctagg cggatcagat taccgttatt ttgaacgtta
    25141 tatctctgtt gctcttgtct attggtctat cagtattttg atggagcaag taggtcgctt
    25201 gattgaaaac aagatggcca tcaaagcacc agaacaagct agaaatgaaa agttaggaga
    25261 attgcgttga tgattacaat tagaaatttg agcaagacat tctcagggca aaaagtttta
    25321 gatagtttgg ctcttgatat tgaaaaaggt caagtgattg ctttagttgg tgcttcagga
    25381 gcagggaaat cgaccttcct tcgtagccta aactatttgg aaaaaccaga ttcaggctcc
    25441 attagcattg gtgactttac ggttgatttt gagaccatta ccacagagcg agtccttatt
    25501 ttacgtcgga aacttgccat ggtttttcaa caatttaatc tttttgagcg tcgtacagcc
    25561 cttgagaatg tcaaagaagg tcttaaggtg gtcaaaaaac tgtctgacca agaagcgact
    25621 aaactggcgc aagcagaatt ggctaaggtt ggtttagcag atcgaaaaca tcattaccca
    25681 cgtcatttat cagggggaca aaaacaacgg gtagctttag caagagctct ggctatgaaa
    25741 ccagatgttt tattactaga tgagccgacc tcggctcttg acccggaatt agttggcgaa
    25801 gtggaaaagt ctattactga tgctgctaaa tccggacaga ccatggtttt agtgagtcat
    25861 gacatgaatt ttgtttacca agtggcagat agagtactct ttttagatca agggaaaatc
    25921 ttggaacaag gaacacctga agaagtcttt agacatcctc aaaaagaacg aaccaaagaa
    25981 ttttttgcaa gctattcaaa aacatacatt taatgatatt cttttgttat aataaaaagg
    26041 tctaggtatt cctgggcttt tcttgttatg ttttttagaa aaacttatgg gaaagaaata
    26101 atgactaggt ggaaatatgt tagtagaaat ctttagcctt tatgtaaaag gtctcattct
    26161 ctcaagcctt actatgattt taatttgttt aatatggact ttatggcgag caaaaaccaa
    26221 aagagataaa acattgattg aaagacaagc ttttctttat gagatgctaa tggttgctat
    26281 tttaaccatc ccaattttat cgtttgcttt tatgagtatt ttggttgtca taaaatccta
    26341 atcattgcaa gaagagatta tcattgctaa aatattggca agagtagatt aaaggagaaa
    26401 aatcatgtac gatacattaa ttattggttc aggaccagca ggaatgactg ccgctttata
    26461 cgctgctaga agtaatttat ctgttgccat tattgaacaa ggggcacctg gtggtcagat
    26521 gaacaacact tttgatatag agaattaccc gggatatgat catatatctg gaccagaatt
    26581 agctatgaaa atgtacgaac ctttagagaa gtttaacgtt gaaaacattt atggtattgt
    26641 tcaaaaaata gaaaattttg gtgactataa gtgtgtgttg actgaagatg ctagttatga
    26701 agctaaaacg gttattattg caacgggagc taaataccgt gtactaggtg ttccaggtga
    26761 agaatactat actagtcgag gagtttctta ttgtgcagta tgtgatggtg cgtttttccg
    26821 tgaccaggat cttttggtcg ttggtggtgg tgactcagca gttgaagaag ctatttatct
    26881 tactcagttt gctaaaaagg taaccgttgt tcatcgccgt gatcaactaa gagctcagaa
    26941 aatcttgcag gaccgtgcct tcgctaatga caaagttgac tttatctggg attctgttgt
    27001 caaagaaatc aaaggtaacg acattaaggt ctccaatgtc ctaatcgaaa atgtgaaaac
    27061 aggccaagtc actgaccacg cttttggagg tgtgtttatc tatgttggta tgattcctgt
    27121 gacaggtatg gtaaaggatc taaaaattac cgattcagaa ggttggatta tcacagatga
    27181 tcatatgagg acaagtatcc ctggtatttt tgcgattgga gatgttcgtc aaaaagacct
    27241 tcgccaaatc acgacagctg ttggagatgg tgcaattgca gggcaaggtg tttatcacta
    27301 ccttgaaagt ttcccttcat aaggttaaaa ctccttcatt tttccttgtc tttccctggg
    27361 aaaagctaaa ttgcataaga cctttaagaa atataaagaa cagttttcct taatatcttt
    27421 cctagataaa tgttgaaaat tttctgaaaa aaggatataa taaatagtat tttagtgaat
    27481 ggagtttaga atgtctataa aagaacaaac agacaataac gaactagaaa atggaatggt
    27541 aaggggctta gaaaatcgtc atgtgcagtt aattgcgatt gcaggaacga ttggaacagg
    27601 tctcttttta ggggcaggac gctctattgc cctaacagga ccatctatta tttttgtgta
    27661 tatgattaca ggtgccttca tgtttatgat gatgcgtgcc atcggtgaaa tgctctatta
    27721 tgatccagat caacacacct ttatcaattt tatttccaaa tacattggtc caggctgggg
    27781 ttatttttcg ggtctatcct attggatttc ccttattttt attggaatgg cagaaatcac
    27841 agcagtaggt gcttatgtgc aattttggtt cccaagctgg ccagcctggt tgattcagtt
    27901 ggttttctta gtcttactta gttcgatcaa cttaattgct gtgcgcgttt ttggggaaac
    27961 agagttttgg tttgccatga ttaagatttt agctatttta gctttgattg caacagctat
    28021 tttcatggta ttgacaggtt ttgaaactca cacaggccat gctagccttt ccaatatttt
    28081 tgaccatttt tccatgttcc caaatgggaa actaaagttc tttatggcct tccaaatggt
    28141 tttctttgct tatcaagcta tcgaatttgt ggggattacc acttctgaga cggctaaccc
    28201 aagaaaagtt ctaccaaagg ctattcaaga aattccaacc cgtattgtga tcttttatgt
    28261 gggagccttg gtctctatta tggcaattgt gccatggcat cagttaccag ttgatgaatc
    28321 tccttttgtg atggtgttca aattgattgg tattaaatgg gcagcagcct tgattaactt
    28381 tgtggtcttg acatcagcag cgtcagcgct taactcaacc ctttattcaa ccggtcgtca
    28441 tctctatcag attgctaatg agactccaaa cgctttgacc aatcgcttaa agatcaatac
    28501 tttatctcga caaggggtgc caagtcgtgc cattattgct tcagcggttg tggttggtat
    28561 ctcagctttg attaatattt tgccaggagt tgcagatgcg ttctcactca ttacggcctc
    28621 ctcatcaggt gtatatattg ctatctacgc cttaaccatg attgctcact ggaagtaccg
    28681 tcaatctaag gactttatgg cagatggtta tttgatgcca aaatataaag tgacaacgcc
    28741 tttgaccctt gctttctttg cttttgtctt tatctctctt ttcttacaag aatccaccta
    28801 tatcggcgcc attggagcaa cgatttggat tattgttttt gggatttata gcaatgtcaa
    28861 atttaaataa taattagcga tatagaactg aatccattaa ctctttctta tttgaggatg
    28921 ttatgatgga tcggttcttt ttttacttta gcgataactc aagttatttc taaaccctag
    28981 ccaaagagtc ctttttaaaa tatgttataa tagtaacaat aattcaaagg agtccccttt
    29041 atgtataaag atgatagttt aactctccat actgatttgt atcagattaa tatgatgcaa
    29101 gtttattttg agcagggcat tcataatcgt catgcggtgt ttgaagtcta tttccgccag
    29161 gaacctttta acaatggtta tgctgttttt gccggtttac agcgcatggt ggagtaccta
    29221 gagcaatttc aattttcaga aacagatttg gcttaccttg aagaactggg ttatccagaa
    29281 aactttttga cctaccttaa agagttacga ttagaattga ccatccgttc agctaaagaa
    29341 ggagatttgg tttttgctaa tgagccgatt gtgcaagtag aaggccctct aggtcagtgt
    29401 cagttggtcg aaacagctct tttaaacatt gttaacttcc agaccttgat tgctacaaag
    29461 gctgctcgta ttcgttctgt gattgaggat gaaccccttt tggaatttgg cacccgtcgt
    29521 gcacaggaac tagatgctgc gatttgggga acccgcgcag cgatgattgg tggagcagat
    29581 gcaacaagta atgtgagagc aggtaaacgc tttgatatcc ctgtttcagg tacgcatgct
    29641 catgctttag tgcaagccta tggtaatgat tatgatgctt tcatggctta tgctaagacc
    29701 cataaagatt gtgtatttct tgttgacacc tatgacacac ttaaagtagg tgtgccaaca
    29761 gctatccgag tagccaaaga attgggtgac aagattaatt ttctaggtgt tcgattggac
    29821 tctggtgact tggcttacct ctcaaaaaca gtccgtcagc agttagacga cgctggtttt
    29881 accgaggcta agatctatgc ttctaatgac ctcgatgaaa ataccatcct caacttaaaa
    29941 atgcaaaagg ccaaaattga tgtttggggt gttgggacca aactgatcac agcctatgat
    30001 cagcctgcct taggtgctgt ttataagatt gtctctattg agcaagaaga tggtagcatg
    30061 cgtgatacga tcaaattatc aaataatgca gaaaaagtat ccacaccagg taaaaaacaa
    30121 gtttggcgca tcaccagtcg tgaaaaaggc aaatcagaag gcgactatat cacgtttact
    30181 gatattaatg ttaatgaatt aactgagatt gagatgttcc atccgaccta tacctatatt
    30241 aagaaaactg tcagaaattt tgatgcaatt cctctcttag ttgatatttt tgtcaaggga
    30301 gaattagttt accaactacc gaccttatct gaaatcaagg cttatgctaa aaaagaattt
    30361 gacaagcttt gggatgaata caagcgtgtc ttaaatcctc aagactaccc agtagactta
    30421 gcccgtgatg tgtggcaaaa taagatggcc ttgattgata acattcgcaa agatgcttat
    30481 ggaaagagtg aatgacatga cattacaaga agagatcatt cgacaattag gcgtcaaggc
    30541 tagcattgat ccgaaagaag aaattcggaa aaccgttgat tttttaaaag cttatctgcg
    30601 taagcactca tttttgaaaa cttatgtctt aggcatttct ggaggtcagg attctaccct
    30661 cgcaggaaag ctagcccaga tggccattgc agagttacgg gaggaaacag gtgatcaagc
    30721 ttaccaattt atagctgttc gcttgcctta tggggttcag gctgatgaag cagatgcgca
    30781 aaaggccttg gcttttattg caccagatca gacccttacc attaatatca aggcagctgt
    30841 ggacggtcaa gtagaggctc tacaagcagc aggcgttgag atttctgatt tcaataaagg
    30901 taatattaaa gcacgtcagc gaatgatcag tcaatatgcc attgctggcc aaatggctgg
    30961 tgctgttatt ggaacggatc atgcggcaga aaacatcact ggtttcttta ctaaatttgg
    31021 tgatggtgga gcagatattc ttcccctctt taggcttaac aaacgtcaag gaaaggctct
    31081 tttgaaagtt ttaggagcag atgctgcttt gtatgaaaaa gttccaactg ctgatttaga
    31141 agatcaaaaa ccaggcttgg ctgatgaggt tgctctaggg gtgacctatc aagacatcga
    31201 cgactatttg gaagggaagc tgatttccaa agtagctcaa gcaactattg aaaaatggtg
    31261 gcataaagga caacacaagc gtcacctgcc aatcaccatt tttgatgatt tttggaaata
    31321 agagatgatg ttcaaagagt aaaaaaagaa aacaaaaaaa gttaggttat cctaactttt
    31381 ttcttgaaga aaatcaaata aggtctataa tagaagtaat cctttagaat agaatggctg
    31441 gataataacc atcttgccaa tattatttca ggtgaagctt atcttaatat tttaggagga
    31501 caataatgtc agcattaaca gagacattta cagaacaatt atttgctcat tacgaagcca
    31561 atgcaaaatt ttcagctatt gagaatgccg ttacgcataa tggtttgcta aaatcattag
    31621 aaacccgtca aagtgaagtg gacaatgatt ttgtgttttc tattgattta actaaagata
    31681 aggtatctaa ccaaaaggct tctggtcgtt gctggatgtt tgctgccttg aacactttcc
    31741 gacacaaatt aatcacagag tttaaattag aaaattttga actgtcacaa gctcatactt
    31801 tcttttggga taagtatgaa aaagctaact ggtttatgga gcaggtcatt gctacagctg
    31861 accaagaatt aaccagtcgt aaagttaagt ttctcttgga tgttccacaa caagatggtg
    31921 gccagtggga catggtggtt tccttgtttg agaagtatgg agtagtgcca aaatctgttt
    31981 acccagaatc aatctcatca agtaacagtc gtgaattaaa ccagtatttg aataaattat
    32041 tgcgccaaga tgctcaaatt cttcgtgacc tgattgcctc aggtgctaag gcagaccaag
    32101 ttgtggatcg aaaagcagag cttcttcagg aaatttttaa cttcttggcc atgacccttg
    32161 gtttaccacc tcgtcatttt gattttgcct accgtgataa agatgaccac tatcatgttg
    32221 agaaaggttt gacaccgcaa gcgttttacg acaaatttgt tggcttaaag ctttctaatt
    32281 atgtgtctgt tattaatgcg ccaactgctg ataagcctta tggcaaatca tacactgttg
    32341 agatgctagg aaatgtggtc ggtagtcgtg aggttcgcta tctaaacctt gatatgaaac
    32401 gtttcaaaga actagctatc aagcagatgc aggctggtga gtccgtttgg tttggctctg
    32461 atgtgggtca agtttcagat cgtcaaaaag gcattttggc aactaatact tacgattttg
    32521 aagctagtat ggatatcaat cttagtcaag ataaggctgg acgtttggat tatagtgaaa
    32581 gtttgatgac acatgctatg gttttaacag gtgttgactt agatgaaaca ggaaaaccgt
    32641 taaaatggaa ggttgaaaat tcatggggtg agaaggttgg tgacaaaggt tactttgttg
    32701 cttcagatgc ttggatggat gaatatacct atcaaattgt tgtccgtaaa gaattcttaa
    32761 cagctgacga gttagcggct tatgaaaaag agccacaagt actagctcct tgggatccaa
    32821 tgggtgcttt agcacaatac taattccttt ctttgcgact gtatgaaatc taaaagctgg
    32881 acaaaacgaa cagcaaacgg attggactcc gcataagaaa gtgaacatga aaaaaattat
    32941 tatgctaaga aaatgacata tgaaaaaaca cgtcttcgat atatggaaac gtgttttttt
    33001 catgtatact ctcttatggc attagttgct atttataaca attttaaata agtctatttt
    33061 gttttaggtt aacgtttgaa aaatcagttg ctaattccct taacgttgta ccttttcttt
    33121 aatacgatta aagaattctg ttttttgttt tatattgtat gtggtaagtc atttgtgtca
    33181 tataaaaagc gagtcctcac agaacgtgga ctcgcttttt atttagatta tcacttaagg
    33241 tagatattaa aagtaactaa atggatatgt aataaaaggt aggtacagac aataagtaga
    33301 ggttagagat taatgagttg tctttttatc atcggtagat ggatgactgc cattgttgtc
    33361 tgtattggtt gaattacttg tatcattgct actactagta tcatctgaag tcgtttggct
    33421 agaagctgtt gtcgtgttat tgctgtaaag attgttgtaa accgaattag tatagtcggt
    33481 gttgctcgca taggttccgc ttaagtagag gaatccacca ctgcgataaa gaccatttgg
    33541 catcgtccaa tcttcactgt aaccatttgt taagtaagtc atcatgctac gataaacgtc
    33601 agatgcaatc tctagacttg atccgtatac tggggtcaag cggtttttgt aacctgtcca
    33661 aacagccatg gcgtagcgct tagtaaagcc aacaaagttt tcgtctggcg ctaatgtacc
    33721 aacataatct ggataaaggc cgtatttttc accaatttta gctagttcct catcagtgta
    33781 gttagaagtc cctgttttac cagcttgcgc aacaccagga atggcagcag cagtacctgt
    33841 accataagtg agaacagttt ttaacatatc tgtcatcata taggccgtgg tttctttcat
    33901 ggcacgtttt cctttttcat caaaagtttt acttgtacca tcactaaatt ccactttatt
    33961 gacatacctt ggtttatgat aaataccacc atttgcaaaa gcagcgtatg cagcggccat
    34021 tttttcacta cttgcaccat attttttatc tgagctactg ttattacttg agatagcgtt
    34081 tgagtagtgc atttcgggat agttaatccc taaactgctt aagaaagatc gagcatagtc
    34141 aagtcctgcg gcttccagtg ctcggactgc tgggacattt cgcgatagca taatagcagc
    34201 ttggattgtc atccatccgt tatatctaag gtcccagtta aacaattggg tagtggttcc
    34261 aggccaataa tagactgagt cattagtcga ctgagcagta gaagtataaa caccagattc
    34321 aatagcagga gcataggctg tgattggctt catggtagaa ccccagtcac gatcagttaa
    34381 aacagcttgg ttagtcccaa atgaaacatt ttcatcttga ttacgtccgc caagctgagc
    34441 aataacatga ccatttgtca catcaacaat cgttgaagca acttggaaat cttggtctgg
    34501 atagtaaaca taatcaccag aatgataaat attataaaga gtctgctgcg catcggggat
    34561 aatattagta taaactttta aaccagcggt aaaaatatct ttattcgttt cttttttgac
    34621 ttcttcaata acttgtttta gataattatc catatatttt ggataagttg agcgctgttg
    34681 gagtgattgt agaccttcag cgacgggagt tgcgatggca gtttcatatt ctgctttcgt
    34741 cagatgtttt tccatgtaca tctgttgcaa cacgacgtta cggcgatttt tagcagcttc
    34801 aggatgaagg taaggatcat attgactagg agcttgaggg attccagcca atagggctag
    34861 ttgggcataa gataaatcct taagatcctt gccataataa gacttagcgg ctgtcagcat
    34921 accatagttg ccattaccca tatatacttt gttgatgtaa aaagtcagga tttcttgttt
    34981 agtatatttt cgctccattt gaagagcaag ccaaacttct tgagccttac gttttaaggt
    35041 ttgatcagat tcattagtag aaaaataggc tagtttaatg agttgctgat caagcgttga
    35101 ccccccttga gtggtctgac tcgttagatt atgaaaggca gcaccaaaaa tacgataaag
    35161 atctactcca cgatggttaa agaaacgttt atcttcaatt gaggtaatag cattaactag
    35221 attaataggg atactatcag ctgttacatt ttcacgcttt tcagaaccca aatcagcaat
    35281 cagattgtta ttaccgtcat aaaccaagct agagtttgtt gattttaact gggcttctga
    35341 cagtttcgga gcactgctaa tgtagaaggt aaacaaaaga ccaccaataa taataacaag
    35401 gataataagg ctaagaattg cacttaatac atactttagc cacttaagga tttttggatt
    35461 tttaattgta atcaccgcct aaaaaatttt gttcaattat gtttaaataa gggacttgtg
    35521 gaaaggctcc aaatgctacc ttaaagccat tttttctgat ataatcaatg ggcatcgatt
    35581 tactgccatt atctatctga taaaatgaaa tcaaggcttg agcaggtagg tagtaagtct
    35641 ccttcagtgt ggaaaagtga agaaggacaa agcagattcc tttttgatgt aaaacgcaag
    35701 ccatatgttc aatctgatgt aaatggaaat ttttcatggg catagctgtt ttttgcctgg
    35761 tttcttttgc ttcaaaatca acataatgtc ctttataaac gccgcaatag tcagtcgttg
    35821 aagcttgtct aaaatacgct tcaacgattt ttgcccgact gcgtttaggg taatccactt
    35881 tgacaatttg gacaggagta ggttttttgt gaatgacagc tatttgacga gataaataat
    35941 aatcatttgt cgcgttgata gcagcttcaa aggacatacc tctattggcg aagtccacct
    36001 tattttgctt tgtttgcttt tgaacggaac ttactttttg tcgaataaga ttatgaggat
    36061 aattaaccat tgttctccta atattatcta gttagtgcta aaaatttaag cacttttatt
    36121 ataacatatt ttttgaaagg ataataccta atgactgcga ttctaattac aggttaccga
    36181 agctttgaaa tagggatttt tgaccataaa gacccacgag tttcaattat taaacaggct
    36241 attcgtaaag atttaatagg ttatttggaa aatggtgtgg attggtttat ctttacaggg
    36301 aacttgggtt ttgaacaatg ggctttggaa gtagctaatg agctaaaaga ggagtatccc
    36361 ttgcagatag gtactatatt cttgtttgaa acgcatggag ataggtggaa tgaaaaaaat
    36421 caagaagttt taagtcagtt tagggctgtt gactttgtaa aatattactt tccaaattac
    36481 gagcaaccga cgcaatttag tcaatattat cagtttttat tagaaaagac agaaggggct
    36541 tatgtttttt atgacacaga aaacgagacc aacttaaaat attttctcaa gaaagcaaaa
    36601 gatatgccgc attatcagtt gctattgcta acctttgatc ggctaaatga tatgtcacaa
    36661 agctagcatt gtatttttag gggtattggt atttaaatac ttgctttttg aactattttt
    36721 ctgtatcatt aataataata ctgaaatata attttggtaa aaagattgac cgttcggaga
    36781 gtaaagaatg acaagtatta tttatagtcc taaagatatt tttgagcaag aatttaagac
    36841 tagtatgcga gggtttgata agaaagaagt tgatgaattt cttgataatg taattaaaga
    36901 ttatgaaaat ttcaatgctc aaattgaagc tttaaaagct gagaacgaag ccttaaaaaa
    36961 ggcgaagttt caagctagaa atacagtttc agcgactgtt caacaaccag taccgcaacc
    37021 gactcgtgtt gctcaatcag ctactaattt tgacatcttg aaacgtatta gtaaattgga
    37081 aaaagaggtt tttggtaaac aaattattga gtaatgaaaa ctgtgcaatt tttggataat
    37141 cgcgtagtat tttaatacta tgaggaaagt ccatgctagc actggctgtg atgccagtag
    37201 tgattgtgct aggcgaacac ataagcctag ggatgtgcat acacattacg gcgaaggaaa
    37261 tggctaagtc gtttgatatg ccaaagtact tctgaaagtg ccacagtgac gtagttttta
    37321 tggaaacgta aaaaatggaa cgcggtaaac ccctcaagct agcaacccaa actttggtag
    37381 gggcatggga tagttggaaa cgaacaagct atcctgactg tcaacagacg gtagacagat
    37441 gattatcgaa ggaaataatt cctagttatt tccggaacaa aacatggctt atagaaaatt
    37501 gcataatagg ttaagctagc acttgctagc ttttatttga tttaaaagaa agagatatat
    37561 gaaagaaaca tttagattag tcgcaactgc agccgcaggt ttagaagctg tcgttggtaa
    37621 agaagtcaga gcactaggct ttgattgtca ggttgaaaat gggaaagttt attttgaagg
    37681 tgatgtagaa gcgattgtta aaacaaatct ttggttacgt gcagcagatc gtatcaaaat
    37741 tatcgtagga caatttcctg ctagaacctt tgaagaatta ttccaaggtg tctttgcctt
    37801 ggattgggaa aattatttac cgctaggagc taaatttcca atctcaaaag ccaaatgtgt
    37861 taagtctaaa ttgcataacg agccaagtgt tcaggcgatt accaaaaagg ccgttgttaa
    37921 gaaactgcaa aagcatttcc acaggccaga aggagttcct cttcaagaag ttgggtcaac
    37981 gtttaacatt gaggtatcta ttttaaaaga ccaagccact attatgattg acacgacagg
    38041 atctagccta tttaaacgag ggtatcgcgt tcaaaaaggt ggagcaccga tcaaggaaaa
    38101 tatggcagct gctatcttgg ccttatctaa ctggtttcca gataaacctc tggttgatcc
    38161 cacctgtgga tcgggaacgt tttgcatcga ggcagccctg attgggatga atattgctcc
    38221 aggatttaac cgttcgtttg cttttgaaga atggagctgg gtagataaag acatggtgca
    38281 acaagttcgt gatgatgctg aacaagaagc taattatgaa atcgaattag atatttctgg
    38341 ctttgatatc gatggccgca tgattgagat tgctaaaagt aatgctgaag aagctggttt
    38401 atctgatgtg attaccttta agcaaatgcg tctgcaagac tttcgaacag acaagattaa
    38461 tggtgtagtg atatcaaatc ctccttatgg agaacggttg cttgatgaca aagcggttga
    38521 catcttgtat aatgaaatgg gacaaacctt tgcaccattg aaaacatgga gcaaatttat
    38581 ccttacaagt gatgaacttt ttgaactaaa atacgggcaa aaagctgata aaaaacgtaa
    38641 actttataac ggcaccctaa aagttgattt gtaccaattt tatggggaaa ggataaagcg
    38701 acatctgata tagagaggta gtaagcgtgt cagaagaaag caaagaagtc gaagtaacaa
    38761 aagaatcgca aacattgggg cttaatgaag ccaagtcaat gacaattggt gaagctgtac
    38821 gcaaacagtc agagataaaa gcaggtgtta ctaaggatga tagtatttta gataagtaca
    38881 ttaagcaaca ccgtgacgaa gtttcttctc aaaagtttga tgctaagtat acagagcttg
    38941 atacagctag tttagataac tttatcaaaa aacaaagaga agcattgagt aaagccggtc
    39001 ttgttgatga cgaacctgtg tctgcggagt ctgctgagca agatagcact ttggttgaag
    39061 aagtagctga agacttagct ccaatggaga ctactgcggt ggtaactggg attccggtgg
    39121 aagcgacagt ccctgtgtta gatctagatc catcagagag ggtcattccg gaaccacaga
    39181 taaccaaaga agagccaaaa agagatcagt ttctttctga agatagccac catccagcca
    39241 aacaaaacac gaaaaaaggt tggttaatag ctttatttct actattattg gccattcttg
    39301 cagttgtatt tggttggaac catttcttga gacaagacag tggtaaaaca actcaaacag
    39361 caagtaaaca gacaaagacc tctttgcaga ccgacagtgc taaaaaagca acgcgcttga
    39421 aggctgctgc taaagctttc gaaaaacaat atggtacttt ttatacagat gccacaaaga
    39481 gcaaattaaa aaatagtgcc tttgctactt tgccagattt agaagctgcc ttgaaagctt
    39541 tggaaggctc tgcttactat gataaggcga aagcaaaagt cgattccctt aagaaagcta
    39601 ttgctgctat tacagcggtt aacggtaaat ttgtttccga tgttgttgta gatggtgaaa
    39661 aggtttcggc tgaaatcaag gctgatgcta attttgatga tttatcaagt gcaaccttga
    39721 caacaggaaa tgcaaatctt gatgctgtct tgcaggcaag catcacagaa ggtcgtcagc
    39781 aactagccag caaggctgag gccgctaaag cagctaatga gcaagaagcc caggatcaag
    39841 cagctcaagg acaaagtaca ttagtagcac catctggcta tggcttgaca agttatgatc
    39901 ctgcaagctt acaacggcat ttatcacgtg taccttacaa tcaagatgtt attgctgaca
    39961 gagctaaccc atcgtgggca tttaatccag gagttcttga aaaaattgta gcaacctcac
    40021 aagctagagg ttatatttca ggcaaccaat atattttaga gccggttaat attattaatg
    40081 gcaatggtta ctataatatg tttaagcctg atggcactta tctgttctct attaattgta
    40141 agacgggtta ttttgtagga aatggcaaag gttatgctga tgctttagat tactgagaaa
    40201 atcaaaaaaa ctgagataag gcaacttgtc tcagtttttt gattaataaa gtatgttgtc
    40261 ttaaaatctg cagatagact tgttttttgt aacaagtcaa ataggtcagt aggattgtta
    40321 tgtttgacaa cacactagta tcagatgaca tggcgactaa aaggatcgtc tgaaatccct
    40381 tgatcaataa tcaattgagc ccattctttg gcggcaaaga ggctatgatc cttatagttc
    40441 ccacaggatt caagagttgt tccaggaaca tcttcccaag taatcccagt tgcaatttct
    40501 tctaggctgg atttaatcac cttggcaata tcagtagaac tgtgttttcc ccacatgata
    40561 aggtgaaaac ctgttcgaca gccaaaagga gagcaatcaa tcatcccatc aatgcgttgg
    40621 cggattagct tggcaagtaa gtgttcaatg gtatgcaaac cggctgtttc aatagaattt
    40681 tggttaggct gcactaggcg aacatcaaaa tttgtaatac gatcgccctt gggtccaaat
    40741 tcttcagaaa taagacgaac ataaggggcc tttacaatag tatgatctag ctcaaaactt
    40801 tcgacgataa cttcttttgt catttcaatc tcctttgttt tacactttat cataacacaa
    40861 atagtgagaa agtggctact tgtggaggag aaaaggctaa gaaaacagat caaaggctat
    40921 cataatgacc tgtgcgataa aagtacttac agaaacagta ataaaggttt ctttaaaagc
    40981 atttttgtgg ttaagtcctg tcaatgctaa gaaggtgaga aagacaccac tttggggcac
    41041 aatggtaaag atattagaag caatagtggc aacacggtga atcatttcga gattaaggcc
    41101 ttgatctaaa taatactggg caaagttagg catgacaatt cctagagcac cggaagaaga
    41161 gccggtaata gctgacatag aggaagtcaa cacggctaaa ctaataagag gattaccggg
    41221 aatattcaaa atgagatctg agaagaatgt gaaacctggg gcaatcatca caacggctcc
    41281 gaaggcaact gcagatgctg tcgcaaaaat aggtgcaata gagctgctag ctcctaaatt
    41341 aaagacagca atcttattag gaataaactg tctaaagagc cagcttgcgg tgagaatggc
    41401 agctaaaagt gctatgaaaa taatgttctt cttaaaaaaa tcgtttccga aaaggctacc
    41461 ggttagggcg ataataatga gcaacaataa aggtaagata ctggcaagga aatgtgggag
    41521 attttttgtt ttcacttgta tctcattgtc aaaagcataa gtggtataag tttcacccct
    41581 tgccatactt tttgctagac aatatttcat ataaaagagc ccaaaagtca cgcagccaat
    41641 tgagccaacg atactcggaa tggcggcagc agttagtgag gtgtccaagt attgaatagg
    41701 aataacattt tgaatggcag gtgttccggg taaaatcgtc atggtaaaag tcgcaatacc
    41761 gagccaaaga ggaacttgaa ttaagttcca agccaagtcc atttttttga atagacttcg
    41821 tgcaagcggc aagacagcaa acatgacaac aaagaggctg attcccccgt aagttaatat
    41881 agcactgatc agaaaaatag caacgagtac tttataagga ctatcatgac caactttttt
    41941 taaaatataa tctgcaatag aagtggttgc accgcttgtt tccattaatt tggctaagat
    42001 agaacctaat aaaaagatag caaaataatt gagaatataa gtggagagtg cccccataaa
    42061 ttggttgggt tcttttccaa gtaaggttgt ggttggatcc atttgattaa accaaatgac
    42121 caagctggta gcaagaggcg cagcgatgat aatgttaact tctttgacag acaggtaaat
    42181 aataacaata acacctacca agacccccag agaaccaata atttccatag ttttatgacc
    42241 tccttattag aaaataaaga gacagatcac aagatacagc ctctttatct ctccaaattt
    42301 attgagcagt gtagccaccg tctaagatac aggcttgacc tgtaacacct tttgccttat
    42361 cactggcaag gaaagacaca tagtctgcaa tttcttgaac gtcaatgagg cgtttttgag
    42421 gaacaggtgg gtatggcact tcttcaagaa cattttcaag gggaatacct cttgttttgg
    42481 aaaggtcttc aaactggcca cgaaccagtg gtgtgtcaac atatccagga caaatggcat
    42541 tgaccgtaat gcctgaatca gcagcttcta aggcagttac tttggtcaga ccgatcaagc
    42601 cgtgcttagc tgaattgtag gcggatttgc cagcaaaacc aatgacacca ttgatagaag
    42661 ccatattaat aatacgaccg tgtttttgag ctttcattgt aggaaaagca cgtttaatgg
    42721 caataaatgg tgctgtcaac atgattttaa tcatgaattc aaatttttca gttggaaaat
    42781 cttcaatcat ggcaacatgt tgaaggcctg cgttgttaac caaaatatca atacgaccat
    42841 atttttcaac aaccgtatca atagcagcat tgatggcttc ttctttggtg acatcgcaca
    42901 caacactaaa agcgtcatag ccttctttag tatagtcagc aacaacctga tccagttttt
    42961 cttgattaat gtcagaaaaa acaaccgttt taccttcttt taataaggtt tccccgattt
    43021 gttttccaat tccgcttgca gcaccagtga taaatgcaac ttctttagta tgtgtcatga
    43081 tactatcctc gtctttcttt tggttagtct ttagtttgtt ttatcaatta gggtaacttc
    43141 ggtaacgttt tgcacgtctt caaaggtgta atctgggtta atttcaaggg cgcatagacc
    43201 ttcatcttga tattcaaaga ctcccatttc agtaatgatt aggttaacaa cattttgaac
    43261 agtcagagga agggtgcatt tgtctaaaat ttttgctttg cctttattgg tatgctccat
    43321 tgcaacaatg acttttttag cacctaccaa taagtccatg gcccctccca tcccaggaac
    43381 catttttcca ggaatcagat aattagcaat gctagcttct ttatcaactt gtaaggcacc
    43441 taagacggtt gcggccacat ggccgcctcg aataatacca aaggaagttg agctatcgaa
    43501 gaaagcccct ccaggagcaa tactaacagg ttgcccacca gcattaacaa tactaggatc
    43561 gtagtgatca tctgttaatc cagtgagacc gacaaaacca ttttcggact gcagggtaat
    43621 ggttacacct tcaggaatat agttggctac ttttgttggc aaacctatgc ctaagttgac
    43681 cagtgtattg tgttctaatt cttgtgcaac gcgcttagca atacgtgttt gaatctcttc
    43741 ttttgaaaga acagtagctg atgttcccat gttaggctcc tttcactaag tagttaacaa
    43801 aaatgccagg agtatggaca aaattaggat ccatttgccc cacgtcaaca atttctcttg
    43861 cttcaacaat ggtggttttc gcattagcag ccatcacatg attaaagtta ttttcagaac
    43921 ctgcgtattg caaattgcca tttttatctg ccttgttagc aaaaataagt gcgacatcag
    43981 ctttcaaagg tttttcaaga aggtagtctt tgccgtcaat agtaatgact tcttttcctt
    44041 tggcaacttc ggttcctatt ccagtaggtg ttaagaaacc gcctagccca aaaccgccac
    44101 tgcggatgcg ctcagctaat gttccctgag gtacaagatc aattacagtc tcgccctcag
    44161 tcatttgtcg gcccgcttca cagttgagac cgatatgtga tgcaataata gttgaaaact
    44221 gtttattggc aaccatctta ccaacgcctt tgtcaggaaa accggcatcg ttacagatta
    44281 aagtgaggtc tttgacacct ttttccacaa gtgcatcaat taatttttct ggtgtgccat
    44341 ttgtcatgaa gccaccaacc ataatggtat caccatcttt aacgtgagct accgcttctt
    44401 ttattgtgat ttctttacac attttttcta ccaactttca cgagactaag tattgttttt
    44461 cacgataaca gcagttcctt gtcctccacc aatgcaaagt gttgctagtc ctctggttac
    44521 ttggcgtttt ttcatttcgt ggattaatgt gactagaatg cgagcgccac tggcaccaat
    44581 aggatgacct aaagcgatgg ctcctccatt aacattcacg atttctgggt ttaactttaa
    44641 atcttttaaa accgccaagg actgtgctgc aaatgcttca ttggactcca ctaagtccaa
    44701 atcagaaatt gttaatccag ctttcttaag ggctttttga gtggcaggaa ttggtccagt
    44761 tcccatcagt tcaggtgcaa cacctgcact agcatagctt tcaatagtga ctaaaggtgt
    44821 taaccctaat tcaagagctt tttcttcagt cattaacatc aataaggctg caccatcgtt
    44881 tattcctgag gcattcccag cagtaacggt tccttcttta gggaagaagg caggacgtaa
    44941 ttgctgtaat ttttcaaggc ttgtgtcaac ttttgggtat tcatctgttg taacaattaa
    45001 agggtctttg cgtcgttgag gtacagagac agggacaatt tcgtcagcaa aacgatgatt
    45061 ttctaatgcc ttagcagctt tttcttggct ttctaaagca aattgatctt gctcttctct
    45121 tgagatgcca tatttctgag caacgttttc agcagtaata cccatatgat aattgttgaa
    45181 agcatctgtc aatccatcat gaacaagagt atcaatcaat tgactattac caagtcgctg
    45241 tccaaaacgg tgctgagttg acacataggc tgcctgtgac atgttttcga caccaccagc
    45301 aataacgata tcagcgtcac caagcatgat gctttgcgca gctaattgga tggctttaag
    45361 tccagaaccg caaaccatat ctaatgtgaa agctgtttta tcttcaggaa ttcctgagtg
    45421 gattgcaact tgtcttgcca cattttgtcc taggcctgca tgaaggacgt ttcctaggat
    45481 gacttcatca accatttcag gctttacttg cgttttatca aggatttttt tcagtacagt
    45541 tgttccaagt tcaacagcag agacactttt aaaggagcct ccaaaagctc cgataggagt
    45601 tcgtaaagct tcaacgataa ctatgttttt cataaaataa acatcctttc agttttagaa
    45661 agcgctttct atgtctctaa gataacaaga aaccgctcaa aataaaaata tagaattttt
    45721 ataagcatat aaattttttt gatagatttg gcaatagcaa ttaaaaatca cttatgtcat
    45781 aatggaatta atactatcgg aaaaaagact aatagacaag gggataacca tttggatatt
    45841 aaacaaattc gttattttat cgcaatcgtt gaaaaccatt ttaacttgag ccaggcggcg
    45901 gaactgttgt atgtgtcgca gccgacactt agcatgatga tcaatgattt tgaaaaaagg
    45961 gaaaatgtta agctcttcaa acgaaaaaga ggtcgtatta ttgggttaac ctatcttggt
    46021 gataattatt ataaggacgc tcaaaaggtt ctcggtcttt atgatgacat gtttttgaaa
    46081 ttgcatgatc acagtaaagg gttaaaggga agtatcaata ttggtattcc tcctcttatt
    46141 ttatcagttg ttttctcaga agtaatgcca aaactgattt tagaaaatcc ggggattcaa
    46201 ttcaatgtta aggagattgg tgcttaccaa ctaaaaaatg aactactcgt gggaaatgtt
    46261 gacgtcgcag tcttgttatc cccaacaggc atcgctgata atttggttga gacttatgaa
    46321 atccagagat cagaattatc tgtatgcctg tctccacgcc atcgtttagc ttccaaaaaa
    46381 gttattcagt gggaagattt aacagatgaa caacttgccc tatttgatcc tagtttcatg
    46441 gttcaccatt tagtgcttga agcttgcgag cgtcaccaag tcagacctaa tattattttg
    46501 acgtcctctt cctgggattt tatgcttaat tctaccaaga ttaatcacaa cgtcttaact
    46561 atttgtccca aacctattac agaattatac caattaaagg acattaagtg tattccaatg
    46621 gaacgtccca tttcttggcg tgttgtctta acacgcctcc ggaaaaaaag ttattctgaa
    46681 atagaagcct acatcatgga cgacttgcta cagtcttttt ttaagtagga ttctcaacca
    46741 cttggcccag atgttaattt ttttaaaaat gaattggaat tgtgtaaacg ctcaatttat
    46801 gataaactaa gaggtggctt tctattaatg aaatctagaa tatattgagg tacaaacatg
    46861 gttaatatta ttttattaat tgtttctgcc ctcattggtt taatattagg ttatgcactt
    46921 atttcgatta gactcaagtc tgcgaaggaa gctgcagagt tgactctttt aaacgctgaa
    46981 caagaagctg ttgatattcg tggcaaagca gaagtagatg ctgaacacat caaaaaaaca
    47041 gctaaacgtg aaagtaaagc aaatcgtaaa gaattacttt tagaagcaaa agaagaggca
    47101 agaaaatatc gtgaagagat tgaacaagaa tttaagtctg aaagacaaga gcttaaacaa
    47161 ctcgagacac gcttagcgga gcgctcctta actcttgacc gtaaagatga aaacctatca
    47221 agtaaagaaa aggtactaga tagtaaagaa caaagtctga ccgataaatc taaacacatt
    47281 gatgagcggc aacttcaagt agaaaaactt gaagaggaga aaaaagcaga actggaaaaa
    47341 gttgctgcga tgacgattgc agaagcgcgt gaagtgattt taatggagac ggaaaacaaa
    47401 ctgacccatg aaattgcgac gcgcattcga gatgccgaac gtgacatcaa ggaccgaaca
    47461 gttaaaacag ccaaggactt gttagcgcaa gccatgcaac gccttgctgg tgagtatgtg
    47521 actgaacaaa ctattaccag tgtccatctc ccagacgaca acatgaaggg ccgaattatt
    47581 ggacgtgaag gccgtaatat tcgtacttta gagagcttga ctggcattga cgttattatt
    47641 gacgatactc ctgaagttgt tatcttatca ggatttgatc ctattcgacg tgaaattgct
    47701 cgtatgacct tggaatctct gattgctgat ggtcgcatcc atccagctcg tatcgaggaa
    47761 ttggttgaga aaaatcgtct tgaaatggat aatcgtattc gtgagtacgg tgaagctgca
    47821 gcctatgaga ttggtgcacc aaaccttcat cctgatttga ttaaaatcat gggacgcctg
    47881 caattccgta cctcgtttgg tcaaaatgtc ctacgtcact ctgttgaggt tggtaagtta
    47941 gctggtattt tagctggtga gttaggtgaa aatgttgccc ttgcccgccg tgctggtttc
    48001 ttgcatgata tgggtaaagc tattgaccgt gaggttgaag gtagtcacgt tgagattgga
    48061 atggaatttg cacgtaaata caaagaacat ccagttgttg tcaacactat tgctagccac
    48121 cacggagatg tggagccaga ttctgtgatc gctgtgctag tagctgcagc agacgctctc
    48181 agttcggctc gtccaggcgc tcgtaatgag tcaatggaga attacatcaa gcgtcttcgt
    48241 gatttagaag aaatcgcgac aagttttgat ggggtacaaa atagttttgc tctacaagct
    48301 ggacgtgaga ttcgtattat ggttcaacct gaaaaaattt cagatgatca ggttgtcatt
    48361 ttgtcgcata aagtaagaga aaaaattgaa aacaatctag attacccagg aaatattaaa
    48421 gtaactgtta ttcgtgagat gagagcggtt gattatgcca agtagaaaaa gaggaattat
    48481 cctctttttc tttatgacta gcctttgaaa atgttcttga aaaagactag cctttttgat
    48541 aaactattaa aaagcaacta ataaggagaa tacaatgtct gaacgcggtt tgttaatcgt
    48601 cttttctggc ccttcaggtg tcggaaaagg aacggtgaga caagaaattt tttcaacgcc
    48661 agatcataaa tttgaatatt cggtttcaat gacgactcgt ccgcaaagac cgggcgaggt
    48721 tgatggggtt gattatttct tccgcacacg tgaagaattt gaagaactca ttaaaactgg
    48781 tcaaatgcta gagtatgctg aatatgttgg taattactat ggcacccctt taacttatgt
    48841 taatgagact cttgataagg gaattgatgt ctttttagaa attgaagttc aaggagctct
    48901 tcaggttaag tcaaaagtac cagatggtgt ttttgttttt ttaacaccac cagatttaga
    48961 tgaattagaa gaccgcctgg ttggtcgtgg tacagatagt caagaagtca tagcccaacg
    49021 tattgaaaga gcaaaagaag aaattgccct tatgcgcgaa tacgattatg cagttgttaa
    49081 tgatgaagtt gccttggcag ctgagcgggt taagcgtatc attgagacag aacactttcg
    49141 tgtggagcgc gtgattggtc gttatgataa aatgattaaa ataacaaaaa atccctttaa
    49201 agctaaatag aaaagagtaa gcattatgat gttaaaacct tccattgata ccttattaga
    49261 taaagtacca tccaagtatt cacttgtgat tttacaagcc aaacgtgccc atgaactaga
    49321 agctggtgcc actccaactc aagaatttaa atcagtgaag tcaacacttc aggcacttga
    49381 agaaattgaa tcaggaaacg ttgtgattca cccagatcct tcagctaaac gtgaagctgt
    49441 ccgtgctaag attgaggcag aacgcttggc caaagaggaa gaggaacgta aaatcaaaga
    49501 acaaattgcc aaagaaaaag aagaagaagg agaaaaaatc taaggtttca gaaatcttag
    49561 attttttcat atttagtacg atgtccatga cagaaaagga gaagcaaatg gaaaaagtag
    49621 ctcatgtgat tgtagatatt ccattgatgc aaacggacaa gccattttct tatggtattc
    49681 caaaagagtt agtttctctc gtgcagcttg gttctcgtgt gcatgttcct tttggaaaag
    49741 ggaatcgttt gttgcaaggc tttattattg gttttggcca agaagattca agctctctta
    49801 aactgattca gaccgtttta gatcctgagc cagtcctaaa ccaagagcaa ttgacccttg
    49861 ctgatcagct tcgaaaaaca gttttttctt ataaaatcac gctcttaaaa gcaatgattc
    49921 ctaatcttct taactctaac tatgataaag tgctaaggcc agagtcaggt ctaaaaaagc
    49981 ctgatagaga ctttcttttt gaaggacaac catctgtctt atattctacc ttagaccgcg
    50041 agaagggaaa aatagctctt aagggcatac aagctgggca tattactgtt agttatttag
    50101 ccaaagacaa gaaaaaccta aagacagaaa aatattatca cgtcgactta gacgccttag
    50161 cggtacatcc catctctagt cgtgccaaaa agcgtcaatt attaaaagac tatctgctaa
    50221 cccatacgaa ggaagctaaa cttgcaacgc tttatcaagc cttttctaga gatgtggtga
    50281 cttactttgt gacaaatcac ttaattcgta ttgacgaacg tccaattgat cgcagtgagt
    50341 cctattttga ccagatcaaa ccatcttctt ttttaacctt aaatgaacag caggcgtcag
    50401 ctgttactga aattgttgaa caaattggga aaccgagtaa accttttttg attgaaggga
    50461 ttacaggttc gggtaagaca gaagtttatc ttcatatcat cgaagcggtt ttaaaacagg
    50521 ataagacagc cattgtttta gtgccagaaa tttcgttgac tcctcagatg acctctcgtt
    50581 ttatttcccg tttcggaaag caagtggcta ttatgcattc aggcttatca gatggtgaaa
    50641 agtttgatga gtggcgcaag ataaaaacag gacaggctaa ggttgtggtt ggtgcccgct
    50701 ctgctatttt ctccccacta gagcggattg gtgcaattat tatcgatgag gagcatgaat
    50761 caacctataa acaagaaagt aatccacgat accatgccag agaggttgcc ctgctcagag
    50821 ctaaacacca tcaagcagtt gtggttatgg gctctgctac gccaagtatt gaaagccgag
    50881 caagggctag taagggtgtc tatcatttta ttcaattaac gcaaagagca aaccctctcg
    50941 ctaagattcc agaagtaacg attgttgatt ttcgtgatta tattggacag caagcagtta
    51001 gtaattttac cccatatttg attgataaga ttaaagaacg tttggttaaa aaagaacaag
    51061 ttgtcttaat gttaaataga cgtggttatt ctagttttgt gacgtgtcgg gactgtggtt
    51121 atgtggacaa atgtctcaac tgtgatatct ctttaaccct tcacatggat actaaaacta
    51181 tgaattgcca ttactgtggg tttcaaaaac ctatcccaat tacttgtcct gagtgttata
    51241 gcaatagtat ccgctattat ggcactggaa ctcaaaaagc ttttgatgaa ttgcaagggg
    51301 ttattccaga agctaggatc ttgagaatgg atgttgacac tacacgaaaa aaaagaagtc
    51361 acaaaaccat actagatagt tttggtcgcc aggaagcaga tattttgtta gggacgcaaa
    51421 tgattgccaa aggtctggat tttccaaatg tgactttagt tggggtacta aatgcagata
    51481 cctccttaaa tttgccagat tttcgagcgt cagaaaaaac gtttcaattg ttaacacagg
    51541 ttgctggtcg ggcaggccgt gcccataagc caggggaagt cttgattcaa acttataatc
    51601 ccgatcacta tgctattcaa ttagctaaga aacaagattt tgaagccttt taccgttatg
    51661 aaatggcgat tcgccgtcag atggcttatc ccccttacta ctttacagtg ggtattacgc
    51721 tttcgcatcg tttagaagca tcggttgtaa aaaaagctta tcaagttaca gaactgctaa
    51781 agagtcactt atcggataat attaaaatat taggaccgac tcctaagcca attgctagaa
    51841 cacacaattt ataccactat caaattttgt taaaataccg ttttgaagat aacctagaag
    51901 agacgctcaa tcgtattctt gattggagtc aagaagcaga taatcgtcat ttaaaactaa
    51961 ttattgattg tgaaccgcaa caatttttat aaggtaaatc actaaatcta ggatgatcag
    52021 ttatgatata ataaaaatac aaagaggaaa gtcatgataa aattattatt tatgggaact
    52081 ccccaatttt cagcaactgt attgaagggc ttgttagata atcctgccta tgagatttta
    52141 ggagtggtta ctcagcctga tcgagctgtt ggacgcaaaa aagatattaa ggtaacacct
    52201 gtaaagcaat tagctcttga gcatggaata tcaatctatc agccggaaaa attatcaggc
    52261 tctcaagaac tcattgagat tacgggactt ggtgcagatg gtattattac agcagcattt
    52321 ggccaatttt taccaacact attacttgat tcagtttcat ttgctattaa tgtacatgca
    52381 tcattgttac ctaaatatcg aggtggagca cctatccatt atgctattat gaatggagat
    52441 aaagaggccg gcgttactat tatggaaatg attaaagaaa tggatgcagg tgacgtggtc
    52501 gctaaagcaa gcactccaat tcttgaaacc gataatgtag gtactctttt tgagaaatta
    52561 gccatcattg gtcgagactt acttttggat agtttgccag cttatctttc tggagaatta
    52621 aaacctattc ctcaagatca cagccaagct actttttcac ctaatatctc tccagaacaa
    52681 gaaaaattag attggacaat gtctaatcaa gaagtgttca atcatattcg aggtatgaac
    52741 ccttggccgg tagcgcatac gtttttagag gggcaacgtt taaaaattta cgaagctcaa
    52801 ctagctgaag gagaaggatt acctggacaa gttattgtca aaaccaaaaa atctttggta
    52861 atagctactg gacaaggtgc tttgtccttg atcgttgtgc aaccggctgg taaacctaaa
    52921 atgtcaataa tagacttttt aaacggcatt ggtagaaaac ttgaagtagg ggacatcatt
    52981 ggcagataat tggaaaaaaa gtacgcgagg caaagccctc cttgtcattg aagctatttt
    53041 tgatcagggg gcttacacaa acatagcgct taatcagcag ctaagcaata aagctttatc
    53101 tgctaaggac agagctctat taactgagat tgtatatggt accgtttcac gtaaaattag
    53161 cttggaatgg tatttagccc attatgtcaa agaccgagat aaattggaca aatgggttta
    53221 ttatctcctt atgctcagtc tttatcaact gacttattta gataagttac cagcgcatgc
    53281 cattgttaac gatgcggttg gtattgccaa aaatcgtggc aataaaaaag gtgcagagaa
    53341 gtttgtcaat gctattttac gtcaattcac caaccatcct ctcccagata tggaaacaat
    53401 taagcgtcga aataagtatt attcggtcaa gtattcactg cctgtttggt tggttaaaaa
    53461 gttagaagac caatttggtt ctgacagatc agtggccatc atggaaagtt tatttgtgcg
    53521 tagtaaggct agtattcgcg tgacagaccc tttgaagcta gaggaagttg ctgaggcttt
    53581 agatgcagaa cgttcccttt tatcagcaac tggtttaacc aaagcgtcag gtcattttgc
    53641 agccagtgat tatttcacaa atggggacat cactattcaa gatgaaagca gtcagcttgt
    53701 agctcctact ttaaacattg acggtgacga cataattctt gatgcgtgta gcgctccagg
    53761 gggtaagacc tctcatatag catcttactt aaaaacaggt aaagttattg ccttagatct
    53821 ctatgatcat aaactagagt tggtgaagga aaatgctaac cgcttaggag ttgctgataa
    53881 cattgagaca agaaaactag atgccagaga ggttcatcgt cattttgaaa aggatagctt
    53941 tgataagatt ttggtggatg ctccttgttc aggaattggt ttgattcgtc gaaaacccga
    54001 tatcaaatat aataaagaaa gtcaagattt taatgctcta caggctatcc agctagagat
    54061 attgtctagt gtttgtcaaa ccttgcgtaa aggtggtata ataacataca gtacttgcac
    54121 tatttttgat gaggagaatc gtcaagtcat cgaagcattt ttacaaagtc atcctaattt
    54181 tgaacaagta aaactgaacc atacacaagc agatattgtc aaggatggtt atcttattat
    54241 cacaccagaa caataccaga ctgatggctt ctttattgga caagtcagac gagtcttgta
    54301 gtattttagg aggaaactga ctgagtcaga aaaaacgtat gaagatttca ttaaaaacag
    54361 acattgggca aaaacgctca aacaatcaag attttatcaa taagtttgat aataaaaaag
    54421 gcatcacttt agtgatttta gcagacggta tgggtggcca cagagctgga aatattgcca
    54481 gtgagatgac agtcacagac ctgggaagag aatgggtaaa aacagacttc acagagttaa
    54541 gtcagattag agattggtta tttgaaacta tccagtcaga aaatcaacgg atttatgatc
    54601 taggccaatc agaagacttt aaaggaatgg gaacgactgt tgaagcagta gctttagttg
    54661 aatctagcgc catttatgct catattggtg attcacggat tggtcttgtc catgatgggc
    54721 attatacctt attgaccagt gatcattctt tagtgaatga gttggttaag gcaggacaga
    54781 tcacagaaga agaagctgct agccatccac aaagaaatat tatcactcaa tctattggtc
    54841 aagcttcccc agtagaacct gatttaggag tgagggtttt ggagccaggg gattatcttg
    54901 tcattaacag tgatggtcta accaatatga tttcaaatga tgaaattgtg actatcttgg
    54961 gcagtaaggt tagtcttgat gaaaaaaacc aagaaatgat tgacttagct aacctaagag
    55021 gaggcctaga taatattaca atcgctttgg ttcacaacga aagtgaggac gtcgaatgat
    55081 tcagattggc aaattatttg ctggtcgtta tcgcattctg aaatctattg gccgcggtgg
    55141 tatggcggat gtttatttag caaatgattt gatcttggat aatgaagacg ttgcaatcaa
    55201 ggtcttgcgt accaattatc aaacagatca ggtagcagtt gcgcgtttcc aacgggaagc
    55261 gcgggccatg gctgaattga accatcccaa tattgttgcc atccgggata taggtgaaga
    55321 agacggacag caatttttag taatggaata tgtggatggt gctgacctaa agagatacat
    55381 tcaaaatcat gctccattat ctaataatga agtggttaga attatggaag aagtcctttc
    55441 tgctatgact ttagcccacc aaaaaggaat tgtacacaga gatttaaaac ctcaaaatat
    55501 cctactaact aaggaggggg ttgtcaaagt aactgatttc ggcatcgcag tagcctttgc
    55561 agaaacaagc ttgacacaaa ctaattcgat gttaggcagt gttcattact tgtctccaga
    55621 acaggctcgc ggctccaaag cgacgattca aagtgatatt tatgcgatgg ggattatgct
    55681 ctttgagatg ttgacaggcc atatccctta tgatggggat agtgctgtta cgattgcctt
    55741 gcaacatttt caaaagcctc ttccatctat tatcgaggag aaccacaatg tgccacaagc
    55801 tttggagaat gttgttattc gagcaacagc caagaaatta agtgatcgtt acgggtcaac
    55861 ctttgaaatg agtcgtgact taatgacggc gcttagttat aatcgtagtc gggagcgtaa
    55921 gattgtcttt gaggatgttg aaagtaccaa acccctcccc aaagtggcct caggccccac
    55981 cgcttctgta aaattgtctc cccctacccc aacagtgtta acacaggaaa gtcgattaga
    56041 tcaaactaat caaacagatg ctttacagcc ccccaccaaa aagaaaaaaa gtggtcgttt
    56101 tttaggtact ttattcaaaa ttcttttttc tttctttatt gtaggtgtag cactctttac
    56161 ttatcttata ctaactaaac caacttctgt gaaagttcct aatgtagcag gcactagtct
    56221 taaagttgcc aaacaagaac tgtatgatgt tgggctaaaa gtgggtaaaa tcaggcaaat
    56281 tgagagtgat acggttgctg agggaaatgt agttagaaca gatcctaaag caggaacagc
    56341 taagaggcaa ggctcaagca ttacgcttta tgtgtcaatt ggaaacaaag gttttgacat
    56401 ggaaaactac aaaggactag attatcaaga agctatgaat agtttgatag aaacttatgg
    56461 tgttccaaaa tcaaaaatca aaattgaacg cattgtaact aatgaatatc ctgaaaatac
    56521 agtcatcagt caatcgccaa gtgcgggtga taaatttaat ccaaacggaa agtctaaaat
    56581 tacgctcagt gttgctgtta gtgatacgat cactatgcct atggtaacag aatatagtta
    56641 tgcagatgca gtcaatacct taacagcttt aggtatagat gcatctagaa taaaagctta
    56701 tgtgccaagc tctagctcag caacgggctt tgtgccaatt cattctccta gttctaaagc
    56761 tattgtcagt ggtcaatctc cttactatgg aacgtctttg agtctgtctg ataaaggaga
    56821 aattagtctt tacctttatc cagaagaaac acactcttct agtagctcat cgagttcaac
    56881 gtcaagttca aacagttctt caacaaatga tagtactgca ccaggtagca acactgaatt
    56941 aagcccatca gaaactactg ctcaaacacc ttaacaaaga atagttagtc tcatgtttta
    57001 ctggcatgcc actaactatt ctttttaact actcgtcata taaagatgca attttccagg
    57061 aattctgata aaatacaaag aaataagggg aaactaatga aaaaatttca attcttttta
    57121 cttatcgagt gtatactgct agctatgggt atcatgacaa tcttggataa tgatttatca
    57181 agttttatcc taattctagt tcttatctta ttagcattac gcttttataa ccaagatagc
    57241 cgcaataatt ttttgctaac tgtcagttta ttgtttcttt ttttaatttt catgcttaat
    57301 ccctacatta tcatggctgt tcttttgggg atagtttaca ttttcattaa ccatttttca
    57361 caagtcaaaa agaagaatcg ctttgccttg attcgtttca aggaagaaaa gattgaagtg
    57421 aataatacca agcatcaatg gattggtact gctaattatg aaagtgatta ttattgtttt
    57481 gatgacatta acatcattcg aatctcagga aatgacacgg ttgacttaac caatgttatt
    57541 gtgacaggaa tggataatat cattgtgata cgtaaaattt ttggaaatac gactatattg
    57601 gtacctattg atgtcactgt tactttagat gttagttcca tatacggaag cgttgatttt
    57661 tttagatgtc agcaatatga tttgcgcaac gaatctatta agttaaaaga aacggataac
    57721 caatccctta aaaaagtcaa aattatcgtt acaactattg ccggaaatgt tgaggtggat
    57781 aggcgatgaa aaaacgttac tatgctcttg tttggctcta ctcaaccatt accattttat
    57841 ctattgtttt tgtggtcatg gataatttag gaatcacttt taactacctt cgcaatcatt
    57901 tatggcaggt cgaacgtcta gggttttcga ttttattgtt ggttgtttct gtgactttat
    57961 tattgttgtt attgtggatt attatggatg ataacagtaa gcgtaacatc aaccaaaatc
    58021 taaaatatat tctcaataat cgacgactct atctagatga gacatcagaa atcaatacta
    58081 atttaagtcg actttctaaa aaaatgtctc acctgactgc taacatgcaa aagaaagaaa
    58141 gtgcttatat tcttgatagc caagaagttg taaaacaaga gcgcaaacga attgcaagag
    58201 atttacatga cacagtcagt caagagctat tcgcttcgtc attgatttta tcaggaattt
    58261 cgatgagttt ggaacaactg gacaaaacac aattacaaac acagttaaca acggttgaag
    58321 caatgttgca aaatgctcaa aatgatctac gcattctcct tttgcatctt agacctaccg
    58381 agctagctaa tcggacttta tctgagggcc ttcatatgat tcttaaggaa ttaacagata
    58441 aaagtgatat tgaagtcatt tataaggaaa ccattgctca gcttcctaaa acaatggaag
    58501 ataatctttt tagaattgcc caagaattca ttagcaacac gttaaaacat gctaaagcta
    58561 gtcgaattga agtttatctc aatcaaacct caacagaact acaattgaag atgattgatg
    58621 atggtgtagg atttgatatg gatcaggtaa gggatttgag ttatggtctg aagaatattg
    58681 aagaccgtgt caatgattta gcaggaaacc tacatttaat tagtcaaaaa ggcaaaggag
    58741 tttccatgga tattagactg ccgatagtga agggagatga cgatgagtaa gataaaagtg
    58801 atattggtcg atgatcatga aatggtccgc atgggactca agagtttttt gaatttacaa
    58861 gctgatattg atgtcgttgg tgaggcctct aatggacgtg aaggggttga tttggcattg
    58921 gctttgaagc cagatgtttt ggttatggat ctagtgatgc cagagttagg cggtgttgag
    58981 gcaactttag aagtcctaaa aaaatggaaa gaggctaagg tacttgtgtt aacttcctat
    59041 ctagataatg aaaagatata ccctgtcatt gatgcaggag cgaagggtta tatgttaaaa
    59101 acatcgagtg cggctgaaat tttaaatgcc attcgcaagg tgtcaaaggg agagctagcc
    59161 attgaaacag aggtagacaa aaaaattaaa gcgcatgacc aacaccctga cttgcatgag
    59221 gaactaacag cgcgtgagta tgatatttta caccttttag ctaaagggta tgataatcag
    59281 accatcgctg atgaactctt tatttcctta aaaaccgtca aaacacatgt gtccaatatt
    59341 ctagccaagt tagaagttga tgaccgaacc caagcggttg tctatgcttt tcgacaccat
    59401 ttagtccccc aagacgataa ttaatgctat aatatagggt atagcaaatt ggaggaaagt
    59461 atggacgcaa aactaaaata caaagctaaa aaaatcaaaa tggtgttctt tgatattgat
    59521 gataccttga gggtcaaaga tacgggttat atgcctgagt cgattcaaag agtatttaag
    59581 gctttgaagg caaaaggcat cttggttggt attgcttcag gtcgcgctcg gtacggtgtt
    59641 ccacaagaag ttcaagattt acatgctgac tattgtgtca aattaaatgg agcttatgtc
    59701 aaagacgatg ctaaaactat tattttccaa gctccgattc cagcagatgt tgttgtggcc
    59761 tataaaaaat gggcggatga tatgggcatt ttttatggaa tggcgggtcg tcatgaagcg
    59821 gtgttgtccg ctcgaaatga catgattagc aatgctattg ataatgtcta cgctcaacta
    59881 gaggtctgtc cggattataa tgagtatcat gatgtttacc agatgtggac tttcgaggat
    59941 aagggagatg gcttgcagtt gcctgctgaa ttagcagagc accttcgttt ggtcagatgg
    60001 cacgataact catcagatgt tgtcttgaaa ggtacgtcaa aagcgctagg tgtttcaaaa
    60061 gtagttgacc atttaggatt aaaacctgaa aacattttgg tttttggaga tgaactcaat
    60121 gacctagagt tatttgacta tgctggtatc agtattgcaa tgggagtatc acatccatta
    60181 ctgcaagaaa aagcagattt tatcacaaaa aaagttgaag aagatggcat tttatatgcc
    60241 ttggaggaat taggattgat tgacaaagaa ttacagtttc cacaattgga tttagaaaat
    60301 catactggac caaaagtaac cattaaaaca aatcatgggg atatgacttt ggtcttgttc
    60361 ccagatcatg ctcctaaaac agtagccaat ttcttaggtt tggctaaaga agggtactat
    60421 gatgggatta tctttcaccg tattattcct gaatttatga ttcaaggtgg tgatccaaca
    60481 ggaacaggaa tgggtggaca atccatctat ggtgagagtt ttgaagatga attttcagat
    60541 gaactgtata accttagagg ggctctttca atggcaaacg caggcccaaa tactaatggt
    60601 agccaattct tcattgttca aaatagcaaa attccttatg ctaaaaaaga attagaacgt
    60661 ggtggttggc ctactccaat tgcagctgct tatgctgaaa atggtggaac tcctcacctt
    60721 gatcggcgtc atacggtctt tggtcagctt gtggacgaaa cttcattcca agttttggat
    60781 ttgattgctg gcgttgaaac tggcgcacag gataaaccta aagaagacgt tatcattgaa
    60841 acaatcgagg tatttgacta atgaaaattg gcgacaaact gcatggcacc atcactggga
    60901 ttaaaccata cggagccttt gttgcccttg aaaatggtac aacaggtctc attcatattt
    60961 cagaaataaa aacgggattt attgacgata ttgatcaatt attggctata ggcaaccagg
    61021 ttttagtaca agtaattgat attgatgaat atagtaaaaa gccaagttta tctatgcgga
    61081 ccttagcaga agaaaaacag cattttttcc atcgtcatcg ttattccaac agtcggcaca
    61141 agattggctt taggccactt gaagagcagt tacctcagtg gattgaagaa agcctgcagt
    61201 ttttaaaaaa gaacactaaa aagagtctgg aaccttagta gttccaaacc cttttttatt
    61261 tcgtcttaat tactggtaca tcatagagtt cagtcgataa atagcgttcg ccattatctg
    61321 gtaaaatagt taacacatgt ttgccttttc ctaactgttt agcgacttca atagcagcgt
    61381 aaagagcagc tccagaagaa atcccaacca ggaagccttc cttagctcct gttagtcgag
    61441 cagtttctaa agcatctttc gatttaacac ggataatttg gtcataggct ttggtatcta
    61501 atgtgtttgg gataaatcca gctgatatac cttgaatttt atgtggtcca ggctcttgac
    61561 cagataagac agcagattct tcagcttcaa cagcatagat aacagtttca gggctagctt
    61621 ttttcaagac atgtgaaaca ccagaaagtg ttcctccagt accaacacca gatacgaatg
    61681 catctaaaga aatctcctta aaagcttcca aaatttcttg agctgttgtt ttttcatgga
    61741 tgcttggatt ggcagggtta ttaaattgca taggcatcca agcacctagt tctattgcta
    61801 aagtttcagt ttttgcaata gcccctttca taccttctgc tccaggtgtt aagacaagct
    61861 ctgcaccata agcctgaatg atttgccgtc tttccaagct catagtttcg ggcataacaa
    61921 taatgactcg atacccttta gcagcaccta cccatgcaag accaatacct gtattaccac
    61981 ttgttggttc gataataacg tcaccaggac ttatcagacc ttcagcttca gcagcttcaa
    62041 tcatcgataa agcaatacga tctttaacag aagatcctgg gttaaaagct tctaatttta
    62101 cataaacgtc agcagcttcg tttggaatta aacggttaag tttgataata ggtgtttgac
    62161 ctactaattc tgttatagtt ttgtaaattt tagtcatagt ttagcctctt ttcttgatac
    62221 aaaataaata cgctgtgtat ttaagtataa ggagagatat tattaaagta aaatacagat
    62281 ttactatcac tctgataata aagccatatc acttttgttg atgattaatc acaggggaat
    62341 tcaataactt tggatccgat tttctcacag cttatctgac catgataata atttgttaaa
    62401 gtatcaatga gattttccac acgttcagta tcacaataaa gtgttgtctt tatcgtgtct
    62461 gaaaacttag tttctgtttc ggttaaagct aattgatcta gcaagttaga gtatagttga
    62521 tattggggat aagaaagtgt gatttctagt cctatctgct gtttaacttc aatgatgcca
    62581 aatcgtttaa tagctgttgc ggtcatgtta gagtatgctc tgattaaccc acctgttcct
    62641 aatttaatac caccaaagta acgcgttacc acaactacta catttgttaa acactgcttt
    62701 tctaacacag aaaggatagg tattccagca gttcctgaag gttcaccatc atcacttgag
    62761 cgcttgatct gtctgttgtt accgataatc atcgcaaagc aggaatgatt agctttgtaa
    62821 tgttcttttt tgatagcatt aacaaaattc ttaccatctt cttcagtgct cactcgtttg
    62881 atatgacaaa tgaaacgaga ttttttaata ctttcttcga aaaaaccact ggctttgatt
    62941 gtcttaaaat gttccataaa aaaattgtac aagaaaagat aaaaattagc aaaaaaaagc
    63001 gaataataaa gtatggagtc tattgaaaat agttatggac ggttgttgct agaaagccag
    63061 ttaccagatt cagcaaagca gcttgctcaa cctttaaaaa gtgtagtaat attgagagga
    63121 aaaatgattt gtcaacgttg tcactatcag cttgatgaag aagcacgatt gccaagtgga
    63181 gcctattatt gccgattttg tcttgtcttt ggacgaaatc aatcagataa attgctctat
    63241 gctatcccac ctatgcattt tccaaaaggt aattatctgg tttggagcgg tcaactaact
    63301 gcttatcaag agataatttc ccaacaatta ttaatcaata tgcaaaatca aaaaacaaca
    63361 ttagttcatg ctgtaactgg ttcaggaaaa acagaaatga tttatgctgc gattgaggcg
    63421 gtaattaaca caggtggctg ggtttgcatt gccagcccaa gagtagatgt ttgtgtagag
    63481 gtggctactc gtttatccca agccttctcc tgcagcatct gtttaatgca cgcagagtct
    63541 cttccttatc aaagagctcc tattatagta gccacaacgc atcagctgct aaaatttcac
    63601 aaggcttttg atctcttaat tattgatgaa gtagacgcat tcccttttgt aaataatatt
    63661 caacttcatt atgctgcaag tcaggcttta aaagaaggtg gcgcaaagat tttattaact
    63721 gcaacttcaa ctagaacttt agaaagaaag gtaaacaagg gagaagtagt caagctgaca
    63781 ttggcgagac gctttcataa taggccatta gttattccaa aatttataag aagttttaat
    63841 ctatttaaaa tgatacatcg gcaaaaactt cctcctaaaa ttttaaaata cttaaaaaaa
    63901 caaagaaaaa caggctatcc ccttttaatt tttctaccca ctattataat ggcagaatct
    63961 gttacagcaa tcttaaaaga gttattgccc gccgaacaaa tagcttgtgt ttctagtcaa
    64021 tcacaaaaca ggaaagaaga tatcacagct tttcgtcaag ggaaaaaaac gattttaatt
    64081 acaacaacaa ttttagaaag gggtgtgaca tttccccaaa ttgatgtttt tgttcttggg
    64141 tctcatcatc gtgtctatag ttcccaaagt cttgttcaaa ttgctggacg agttggaaga
    64201 tctatagaca gaccagacgg aacgttatat ttctttcatg aaggtatcag taaagcaatg
    64261 ctactagcaa aaaaagagat taaagaaatg aattataaag ggtattcgca tgatctgtct
    64321 actatgtcaa caaattagtc aaacaccaat aagtattaca gaaatcatct ttttaaggcg
    64381 tatctcttca ccgatttgtc aacaatgtca aaaaagcttt caaaagatag gaaaaagtgt
    64441 ttgtgcgaca tgttgtgcaa actcagatat aatagcttgt cgagattgtc taaaatggga
    64501 aaacaaagga tacaatgtaa atcatagaag cttatattgt tataatgctg ctatgaaagc
    64561 atacttcagt caatataagt ttcaaggaga ctatttatta aggaaagttt ttgcagtaga
    64621 acttgccgat gttattacca agtactataa aggctatatt ccagtcccgg ttcctgtaag
    64681 tcccggttgt tttcgagaaa gacaatttaa tcaagtgagc gctattcttg aggcagctaa
    64741 tgttagctac ctttctcttt ttgaaaagct agataatact caccaatctt ccagaacaaa
    64801 aaaagagaga ttattagtag aaaaatctta tcgactacta aaagtatcaa acattcctga
    64861 taaaatcctt atagtagatg atatttatac tactggtagt acaattatcg ctcttagaaa
    64921 acaattggct aaagtagcaa atagtgacat taaaagtttg tcaattgcac gttaaaactt
    64981 gcaaattttc atgaaagcag tataatagta ttaaagataa agtaagcgct tcaagcgcga
    65041 gaaagaggta tcctatgatt aagttcagta ttcgtggaga aaatatcgaa gtgacagaag
    65101 ctattcgcga ttatgtagaa tcaaagctta ctaaaatcga aaaatatttt gctaaagacc
    65161 aagaaataga tgcacgtgtt aatttaaaag tttatcggga gagatcttca aaagttgagg
    65221 taacgatccc attagattca gtaacccttc gtgctgaaga tgtttcacag gatatgtacg
    65281 gctctattga tttagttgtt gataagatcg aacgccaaat tagaaaaaat aaaaccaaaa
    65341 ttgctaaaaa acatcgtgaa aaggttccaa ctggtcaagt ctttacaact gagtttgaag
    65401 ctgaagaagt cgatgagata ccagaagtac aagttgtacg tactaaaaat gtgacattaa
    65461 aaccaatgga tgttgaagaa gcgcgtttac agatggaact attgggacat gatttcttta
    65521 tctacactga ttctgaagat ggtgcaacaa acattttata ccgtcgcgaa gatggaaacc
    65581 taggattaat agaagctaaa tagttcacaa ctaaaaccta cagggatgat tatacgtatt
    65641 ttaaaagtgg gaaaaagcta ttcatgttta gaggtgacat gatgaaaatg agattaagtg
    65701 atagatacga cagtcattat gctaacaaaa gtatctatta cagttcctct ttaagtaaat
    65761 cttacgtaaa attagtttga aaaaaagatt agtcccaatt ctgggctaga aattctcaaa
    65821 aaatatgaaa aagcgcgttt tcagaatata aagcgcgttt ttttcttttt ccatttaaca
    65881 ataaaaaact catgacgaac atggtatcat aagagaattt ttactttttt aaaaaaggtc
    65941 aaagactttc tgacaccaaa taaaaataga attttttcta actaaaaata atagcacaat
    66001 ctttggcagc aatctgaatt gttttttcca taaaagattt aagcacttac gtttgcttaa
    66061 aatataggtt atgtgacgtg cgtgcaagat cagattataa caaaatagtt ccaaataagc
    66121 ctatcactga gaaagcatca cagaagagtt aaactttttt gtattagcgt tttatcagta
    66181 caacctaaca cttattttta taaaaaaata aaaaagctat tgacaatctt atacaagata
    66241 acgtatacta ataaagctgt tgtaaatatg gtaaagcaat agatgctatc aggaaaaaat
    66301 gtgaa
//
LOCUS       DAXMQE010000006        64917 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.006, whole genome shotgun sequence.
ACCESSION   DAXMQE010000006 DAXMQE010000000
VERSION     DAXMQE010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 64917)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 64917)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..64917
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.006"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            <1..163
                     /locus_tag="ACF4ZO_000418"
     CDS             <1..163
                     /locus_tag="ACF4ZO_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0019346 - transsulfuration [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="PLP-dependent transferase"
                     /protein_id="HFD5485996.1"
                     /translation="VESILSHPATMSHACLSSQARLEQGVVDGLLRLSCGVENIEDLL
                     ADFEQALAF"
     gene            374..2875
                     /gene="leuS"
                     /locus_tag="ACF4ZO_000419"
     CDS             374..2875
                     /gene="leuS"
                     /locus_tag="ACF4ZO_000419"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004823 - leucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006429 - leucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HFD5485997.1"
                     /translation="MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKD
                     MQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTADQ
                     AEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGNEMPVWIADYVLASYGT
                     GAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAAFTEDGLHINSGFLDGLDKASA
                     IAKMVEWLEAEGVGNEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLV
                     LPVTKDIRPSGTGESPLANVTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD
                     KVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHL
                     GEELWQALTASGESISYVPWPSYDKSKLVENDVEIVVQIKGKVKAKLVVAKDLSREEL
                     QEVALANEKVQAEITGKDIIKVIAVPNKLVNIVIK"
     gene            3182..4615
                     /locus_tag="ACF4ZO_000420"
     CDS             3182..4615
                     /locus_tag="ACF4ZO_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFD5485998.1"
                     /translation="MEMLLAPLNWFSQNILQNPAFFVGLLVLIGYLLLKKPIYEVFAG
                     FVKATVGYLILNVGAGGLVTTFRPILVALAKKFELKAAVIDPYFGLAAANTKLEEMGF
                     ISVATTALLIGFGVNILLVALRKVTKVRTLFITGHIMVQQAATISVFVLLLIPQFQNA
                     FGAWAVGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAPFFGKKE
                     ENLDNLKLPTFLNIFHDTVVASATLMLVFFGAILAVLGPDIMSDVDLIGPGAFNPAKQ
                     AFFMYILQTSLTFSVYLFILMQGVRMFVSELTNAFQGISSKLLPGSFPAVDVAASYGF
                     GSSNAVLSGFAFGLIGQLITIALLVIFKNPILIITGFVPVFFDNAAIAVYADKRGGWK
                     AAVALSFISGILQVALGAVAVGLLGLTGGYHGNIDLVLPWLPFGYLFKFLGIAGYVLV
                     CIFLLAIPQLQFAKAKDKEAYYRGEAQ"
     gene            4686..4964
                     /locus_tag="ACF4ZO_000421"
     CDS             4686..4964
                     /locus_tag="ACF4ZO_000421"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFD5485999.1"
                     /translation="MVKVLTACGNGMGSSMVIKMKVENALRQLGVTDIQSASCSVGEA
                     KGLASGYDIVVASNHLIHELDGRTKGHLVGLDNLMDDNEIKTKLQEVL"
     gene            5087..5572
                     /locus_tag="ACF4ZO_000422"
     CDS             5087..5572
                     /locus_tag="ACF4ZO_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFD5486000.1"
                     /translation="MNLKQAFIDNNSIRLGLSADTWQEAVQLAVQPLIDSKAVTSAYY
                     DAIIASTEKYGPYYVLMPGMAMPHAEAGLGVNRNAFALITLTKPVTFSDGKEVSVLLT
                     LAATDPSIHTTVAIPQIVALFELDNAIERLVACQSPKEVLEMVEESKDSPYLEGMDLN
                     A"
     gene            5663..6325
                     /locus_tag="ACF4ZO_000423"
     CDS             5663..6325
                     /locus_tag="ACF4ZO_000423"
                     /EC_number="4.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HFD5486001.1"
                     /translation="MTHIPNLQVALDHSDLQGAVKAAVAVGHEVDVIEAGTVCLLQVG
                     SELVEVLRSLFPEKIIVADTKCADAGGTVAKNNAKRGADWMTCICCATIPTMEAALKA
                     MKEERGDRGEIQIELYGDWTYEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNKV
                     KTLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITEAEDPAAAARAFKDEIKRI
                     WG"
     gene            6330..7193
                     /locus_tag="ACF4ZO_000424"
     CDS             6330..7193
                     /locus_tag="ACF4ZO_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016861 - intramolecular oxidoreductase
                     activity, interconverting aldoses and ketoses [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HFD5486002.1"
                     /translation="MARPIGIYEKATPKQFTWRERLQFAKDLGFDFVEMSVDESDARL
                     ARLEWTKEERLDLVKAIYETGIRIPTICFSGHRRYPLGSNDPAIEAKSLKLMKQCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPETRARFIKNLRQSCDWAEEAQVMLSIEIMDDPFIN
                     SIEKYLAVEKEIDSPYLFVYPDAGNVSAWHNDLWSEFYNGHKSIAALHLKDTYAVTET
                     SKGQFRDVPFGQGCVDWQELFAVLKKTNYNGPFLIEMWSENCDTVEETKAAIKEAQDF
                     LYPLIEKAGLA"
     gene            7195..7899
                     /locus_tag="ACF4ZO_000425"
     CDS             7195..7899
                     /locus_tag="ACF4ZO_000425"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HFD5486003.1"
                     /translation="MAKNLQEMRERVCAANKSLPQHGLVKFTWGNVSEVCRELGRIVI
                     KPSGVDYDLLTPENMVVTDLDGNVVEGDLNPSSDLPTHVELYKAWPEVGGIVHTHSTE
                     AVGWAQAGRDIPFYGTTHADYFYGPVPCARSLTKAEVDGAYEQETGNVILEEFSKRGL
                     DPMAVPGIVVRNHGPFTWGKTPEQAVYHSVVLEEVARMNRLTEQINPRVEPAPRYIMD
                     KHYLRKHGPNAYYGQK"
     gene            8218..9864
                     /locus_tag="ACF4ZO_000426"
     CDS             8218..9864
                     /locus_tag="ACF4ZO_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFD5486004.1"
                     /translation="MMILDKKSYDLLSYLLKLETPETVMAISHALNQSRRKVYYQLDK
                     INQALPKGVDQIISYPRLGILLTADQKAACRLLLEEVTDYNYVMKSDERRRLSSIYIA
                     VSTERVTIDKLMQINDVSRNTILNDLTELREELEDKQYKIQLHATKARGYYFGCHPMA
                     LIQYLYKLLVDVYQGGNTSFIDIFNRKLSEIQGLSVYFSKDILTYFHEYLFLSQASLG
                     KTINTQDSQFMLQILPFMLLSYRNMRLDSETKSALKQEFHLIWKRKEYHIAQDLAREL
                     YHNFKLHLDDIEVSMVAMLMLSFRKDQDHHVESQDYDDMRATISHFIDQLESRYQLHF
                     THKQDLLKQLTTHCKALVYRKAYGIFLVNPLTDHIKEKYEELFAMTQSCATILEQDWT
                     ISLTDDDIAYLTIHLGGELRHNNTEQEKTKLVIVSDDGIGIQKLLFKQCQRYLANGQI
                     EAVFTTEQYQSVYDLLAVDMIVATTDTLKTKIPMLIVNPILSDDDIIKLIRFSKQGRL
                     SEHSRFSTELTKAIEAVVKDESDRYALVSKIEKLIHRELL"
     gene            10117..11208
                     /gene="ulaG"
                     /locus_tag="ACF4ZO_000427"
     CDS             10117..11208
                     /gene="ulaG"
                     /locus_tag="ACF4ZO_000427"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_function: GO:0035460 - L-ascorbate 6-phosphate
                     lactonase activity [Evidence IEA];
                     GO_process: GO:0019854 - L-ascorbic acid catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HFD5486005.1"
                     /translation="MTKVQDITRESWILNTFPEWGTWLNEEIEQEVVPADNFAMWWLG
                     NCGIWIKTPGGANVVMDLWSNRGKATKQVKDMVRGHQMANMAGARKLQPNLRAQPMVI
                     DPFMINELDYYLVSHYHSDHIDINTAAAIINNPKLNHVKFVGPYECGEVWKNWGVPKD
                     RIMILKPGDSFEFKDIKITAVESFDRTCLVTLPIQGADAQDGDLAGLAITDDDMARKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGRDYDIDVVLNNYGENPIGIQDKMTSVDLLR
                     MAENLRAKVVIPVHYDIWSNFMASTDEILELWKMRKERLQYDFHPFIWEVGGKYTYPQ
                     DQNRIEYHHPRGFDDCFLEDSNIQFKALL"
     gene            11695..12891
                     /locus_tag="ACF4ZO_000428"
     CDS             11695..12891
                     /locus_tag="ACF4ZO_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HFD5486006.1"
                     /translation="METILEVKHLSKIFGKKQKAALEMVKTGKNKSEIFKKTGATVGV
                     YDASFEVKKGEIFVIMGLSGSGKSTLVRMLNRLIEPSAGSILLEGKDISTMSADQLRE
                     VRRHDINMVFQSFALFPHKTILENTEFGLELRGVPKEERQRLAEKALDNSGLLDFKDQ
                     YPNQLSGGMQQRVGLARALANSPKILLMDEAFSALDPLIRREMQDELLDLQDSMKQTI
                     IFISHDLNEALRIGDRIALMKDGQIMQIGTGEEILTNPANEFVREFVEDVDRSKVLTA
                     QNIMIKPLTTTVELDGPQVALNRMHNEEVSMLMATNRRRQLVGSLTADAAIEARKKGL
                     PLSEVIDRDVRTVSKDTIITDILPLIYDSSAPIAVTDDNNRLLGVIIRGRVIEALANI
                     SDEDLN"
     gene            12907..14634
                     /locus_tag="ACF4ZO_000429"
     CDS             12907..14634
                     /locus_tag="ACF4ZO_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003060437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate binding
                     protein"
                     /protein_id="HFD5486007.1"
                     /translation="METILQTKLPVAQLVEQLTEWLTKTFSGLFDIMQVVGSFLMDWM
                     TKTLLFIHPLLFIVLVTAGMFFLAKKKWPLPTFTLLGLLFIYNQGLWKQLMNTFTLVL
                     VASLISVLIGIPLGIWMAKNATVRQIVNPILDFMQTMPAFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLAIRDIPTELIEASDAFGSTGKQKLFKVELPLAKNTIMAGVN
                     QTMMLALSMVVTGSMIGAPGLGREVLSALQHADIGSGFVSGLALVILAIVLDRMTQLF
                     NSKPQEKAKAGKTNKWIGLAALAIFLIAALGRGIMTMASGMADKGETVNIAYVQWDSE
                     VASTHVIAEVLKNEGYHVTLTPLDNAVMWQTVANGNADFSTSAWLPVTHGQQYQKYKS
                     KLDDLGPNLKGTKLGLAVPKYMTDVNSIEDLSKQADQKITGIEPGAGIMAAAKKTLKE
                     YHNLSSWELVAASTGAMTTSLDQAIKKKDPIVVTAWSPHWMFAKYDLKYLKDPKETFG
                     STENINTIARKGLKKDLPNVYKIIDKFHWTQKDMEAVMLDINKGMSPEAAAKKWVEAN
                     KSKVSSWTK"
     gene            14765..17407
                     /gene="polA"
                     /locus_tag="ACF4ZO_000430"
     CDS             14765..17407
                     /gene="polA"
                     /locus_tag="ACF4ZO_000430"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006261 - DNA-templated DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HFD5486008.1"
                     /translation="MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGF
                     HLMLDHMMKRVQPTHVLVAFDAGKTTFRTEMYADYKAGRAKTPEEFREQFPYIREMLT
                     ALGIAYYELEHYEADDIIGTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKK
                     GVAEFEEFTPAYLMEKMGLTPNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGS
                     LEGIYEHIDGFKASKMKENLINDRDQAFLSKTLATINTASPITIGLDDIVYNGPDVAS
                     LSQFYDEMDFVQLKKGLASQMPQEPVAAISYQEVTNVSADLFSAEDIFYFETLRDNYH
                     REAIIGFAWGHGEQIYASTDLSLLATDSFKQVFQKPIATYDFKRSKVLLSHLGIELVA
                     PSYDARLANYLLSTVEDNELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLA
                     RKVKVLLDSKSQMLDKLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQ
                     NKVIIEALTQEIYDMAGQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLE
                     RLAPIAPIVAKILAYRQITKLQSTYVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDP
                     NLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGA
                     DIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGISDFGLSNNLGITRKQAKTYI
                     DTYFERYPRIKAYMENVVREAKDKGYVETLFKRRRELPDINSRNFNVRSFAERTAINS
                     PIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTM
                     EAAVDLAVPLCVDESTGQSWYEAK"
     gene            17585..18040
                     /locus_tag="ACF4ZO_000431"
     CDS             17585..18040
                     /locus_tag="ACF4ZO_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0120225 - coenzyme A binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HFD5486009.1"
                     /translation="MIYSFQNPSEDVLKAYLESAKTIAVVGLSDRKDTAAYGVAKFMQ
                     AMDYRIIPVNPKLAGQLILGEKVYASIKAIPFEVDIVDVFRRSEFLPEVARDFLAGQA
                     KVFWAQLGLENQEAQTILRSAGKEAIVMNRCLKIDYLQLVAKPECITNH"
     gene            18092..18559
                     /gene="perR"
                     /locus_tag="ACF4ZO_000432"
     CDS             18092..18559
                     /gene="perR"
                     /locus_tag="ACF4ZO_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide-responsive transcriptional repressor
                     PerR"
                     /protein_id="HFD5486010.1"
                     /translation="MDIHSHQQALDAYENVLEHLREKHIRITETRKAIISYMIQSTEH
                     PSADKIYRDLQPNFPNMSLATVYNNLKVLVDEGFVSELKISNDLTTYYDFMGHQHVNV
                     VCEICGKIADFMDVDVMDIAKEAHEQTGYKVTRIPVIAYGICPDCQAKDQPDF"
     gene            complement(18662..19525)
                     /locus_tag="ACF4ZO_000433"
     CDS             complement(18662..19525)
                     /locus_tag="ACF4ZO_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HFD5486011.1"
                     /translation="MSIKAIKGQARDTLKNLSGKYLLFLIPTLLFMFHFGIEIHQGYV
                     LSSGIEVSLAASYFPLLLGLILSLFILSASFTMIDVVRHFRQKVSFAESTTAFSKEFF
                     GNLLVLAITKWLFFLIWSLIWFFGLFIFLSGLSAFLVNAKSGGSTVISLIFLLFGAVL
                     SLIGFGIYINRYYAYSLSEYLLYDKVKEGTYLGAIAVIETSVAMMKGYKWKLFFLQLS
                     FTGWFLLNIVTFGLLNIYLLPYFTTANVIFYDQLKKRFKDKDDPIEGEHLSLHQLNKK
                     PTPMMYDDQKD"
     gene            19562..19747
                     /locus_tag="ACF4ZO_000434"
     CDS             19562..19747
                     /locus_tag="ACF4ZO_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486012.1"
                     /translation="MRQLTIILTILFWESMTNYGFFDKMIGARTTCHLEALHYDGNSG
                     RSKKLKTVYLDSKEEST"
     gene            19744..20886
                     /gene="tgt"
                     /locus_tag="ACF4ZO_000435"
     CDS             19744..20886
                     /gene="tgt"
                     /locus_tag="ACF4ZO_000435"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008479 - tRNA-guanosine(34) queuine
                     transglycosylase activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HFD5486013.1"
                     /translation="MTDYPIKYRLIKTEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKAIGSGIILSNTYHLWLRPGDELIARSGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAADLVAMDFLGYSI
                     GGLAVGESHEEMNAVLDFTTPLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSEGRLVIKNAKFAEDFTPLDHDCDCYTCQNYSRAYIRHLLKADETFGIR
                     LTSYHNLYFLVNLMKKVRQAIMDDNLLEFRQDFLERYGYNKSNRNF"
     gene            21104..21415
                     /locus_tag="ACF4ZO_000436"
     CDS             21104..21415
                     /locus_tag="ACF4ZO_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CHY zinc finger protein"
                     /protein_id="HFD5486014.1"
                     /translation="MTDCFGIDLDQEYRCLHYHTPLDIVGLKCAFCQTYYACYHCHDQ
                     LADHAFVPTGHQETSPVICGHCRKLLSLAEYGCGCCPYCQSPFNPACHRHKDIYFLKE
                     S"
     gene            21419..21958
                     /locus_tag="ACF4ZO_000437"
     CDS             21419..21958
                     /locus_tag="ACF4ZO_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HFD5486015.1"
                     /translation="MFTTKELVKVAMMTTLIIILGFIPAIPLGFIPVPIVLQNLGVML
                     AGLMLGGKKGTLSVFLFLVIGLFLPVFSGSRTTIPVLMGPSAGYVIAYLLVPIVFSLL
                     YRNWFSKSTPLAFLALFISGVLLVDVMGAIWLAAYTGMPLMTSLLSNLVFIPGDTIKA
                     IIATIIAVKYKDSFLNTKQ"
     gene            22098..22877
                     /locus_tag="ACF4ZO_000438"
     CDS             22098..22877
                     /locus_tag="ACF4ZO_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFD5486016.1"
                     /translation="MKLTTLGSWGAYPYQDAGTTSYLVTGHDGFQLLMDAGSRALNEL
                     EKEISPLDLDAVIISHYHPDHVADLGVLRHYFQLYPKHLWQPKVLPIYGHDEDRHEFA
                     KLSIPDVSEGRAYDVTGVEQIGPFDITFLKTVHPVVCYAFRIVERATGQVLVFTGDSG
                     YFEGLADFAKEADLFLADVYLYEGNENHMAHLTSKEAGLMASQAGVKKLVLTHMPPVP
                     PEGIDPDNHLEVLRQETQAYAGNIPVDLALPHKSWNLGSLS"
     gene            22877..23392
                     /gene="tadA"
                     /locus_tag="ACF4ZO_000439"
     CDS             22877..23392
                     /gene="tadA"
                     /locus_tag="ACF4ZO_000439"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008251 - tRNA-specific adenosine
                     deaminase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0002100 - tRNA wobble adenosine to inosine
                     editing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HFD5486017.1"
                     /translation="MPYSLEEQTYFMQEALKEAEKSLQKAEIPIGCVIVKDGEIIGRG
                     HNAREESNQAIMHAEMMAINEANAHEGNWRLLDTTLFVTIEPCVMCSGAIGLARIPHV
                     IYGASNQKFGGADSLYQILTDERLNHRVQVERGLLAADCANIMQTFFRQGRERKKIAK
                     HLIKEQSDPFD"
     gene            complement(24006..25238)
                     /locus_tag="ACF4ZO_000440"
     CDS             complement(24006..25238)
                     /locus_tag="ACF4ZO_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
                     /protein_id="HFD5486018.1"
                     /translation="MGVMMKQKIKILTVIGLMTVGMSACHNTSKPSNTDSVFSLTGKK
                     RQQIVKQVRQRYYFQQLSKTEQENYLTLYDSLAQFREIISLTPASKKSLIKTIDAFVM
                     DNPEFYWITSADYRFEFSDQTVFVTFPIPEDAKNVYQDLQAIGNDIVANMPSKDRYEQ
                     VKYFYEVIIRDTDYNKKAFEAYQSGSQAQVASNQDIKSVFIDHLSVCNGYAQAFQFLC
                     QKAGIPVAYIRGTGTSQQPQQSFAHAWNAVQINNTYYGVDVTWGDPVFDNHLSHQKQG
                     TINYSFLCLPDHLMALSHQPSKDIAFNTKERFENVWTIPSCTDDSLLYSKRHQSYIST
                     FDSDAILESLENQLLNRQEPLSLQFAHQDDYQQMVTDLTTNQTGYHNLFNQYWNNYTG
                     FTYGLLPETLSISFASRN"
     gene            25438..25536
                     /gene="ffs"
                     /locus_tag="ACF4ZO_000441"
     ncRNA           25438..25536
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="ACF4ZO_000441"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            25638..26342
                     /gene="speG"
                     /locus_tag="ACF4ZO_000442"
                     /pseudo
     CDS             25638..26342
                     /gene="speG"
                     /locus_tag="ACF4ZO_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921857.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="streptococcal pyrogenic exotoxin SpeG"
     gene            26798..28147
                     /locus_tag="ACF4ZO_000443"
     CDS             26798..28147
                     /locus_tag="ACF4ZO_000443"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004347 - glucose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HFD5486019.1"
                     /translation="MSHITFDYSKVLESFAGQHEIDFLQGQVTEADKLLREGTGPGSD
                     FLGWLDLPENYDKEEFARILTAAEKIKADSEVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTAKERKAPQILYAGNSISSTYLADLVEYVQDKEFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDKVKGAVKVEADANNWETFVVPDNVGGRFSVLTAVGLL
                     PIAASGADITALMEGANAARKDLSSDKISENIAYQYAAVRNVLYRKGYITEILANYEP
                     SLQYLGEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGYRNLFETVIRVDN
                     PRKNVIIPELAEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGGVPNMFVTLPAQDEF
                     TLGYTIYFFELAIAVSGYMNAVNPFDQPGVEAYKRNMFALLGKPGFEALSAELNARL"
     gene            complement(28495..30003)
                     /locus_tag="ACF4ZO_000444"
     CDS             complement(28495..30003)
                     /locus_tag="ACF4ZO_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD5486020.1"
                     /translation="MLDYYLESDIIDQKILLAILLTEKELTMAAACSQTTLTALKIKQ
                     YLRQFNALFKGYLRIELIKSRIYCEVLNDKREAFFYDIFALSDTLKMLTFLLLDNPKH
                     KSIAVYTRKQGISQSKAYRLIHKLKHYLQDIGLNIVDNTVIGDELKIRYLIALLHKEY
                     GIILYDIQPADIETIHAFIFAAQKNLQPSAFLDRRFLFFDVLLMLTWKRHRYPVHLPH
                     LALFEHLKSLPIFDNIKTIAVDELAPRTRVTFSSDDFDYLFLIYLTTDNSFLSGYWTS
                     HQRQQLYHLITKDPDYHLLIHRLQALVGKYSDIHEHIPNLIPFFKRTLYNLQTLITFD
                     GYYFDQYQGNMLLLDKLETVIKDWLYDTGRQGSISSGHLHLMCLYLEQILESSIAPIN
                     ITVIESQETVGNVIANFITSTIPSYKVELSRVNILSDNIYPYDKPVDLVVTSQKLLPF
                     LKELGVFPKETRLFGLSLDCIQQQREDLIKTILALHQNHYQKRLEELWRVPS"
     gene            30691..31362
                     /locus_tag="ACF4ZO_000445"
     CDS             30691..31362
                     /locus_tag="ACF4ZO_000445"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HFD5486021.1"
                     /translation="MTRLLKRYPITIFLLGLTGLIFIAMQVVYGHLATGAQAIYQVGG
                     MFGLLVKAMPDQLWRLVTPIFIHIGFGHFFVNGLTLYFVGQIVEDLWGSRRFLLLYVL
                     SGVMGNAFTFWLTPETVAAGASTSLFGLFAAIVVLSFLGKNQALKDLGKSYQTLIVVN
                     LLMNLFMPNVSMAGHIGGVVGGALLSIVFPTKMRVITMKKTKRMLALVSYGIILVGVL
                     VLGFL"
     gene            complement(31460..32359)
                     /gene="galU"
                     /locus_tag="ACF4ZO_000446"
     CDS             complement(31460..32359)
                     /gene="galU"
                     /locus_tag="ACF4ZO_000446"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003983 - UTP:glucose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0006011 - UDP-glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HFD5486022.1"
                     /translation="MTKVRKAIIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVEE
                     ALKSGIEEILIVTGKSKRSIEDHFDSNFELEYNLQAKGKIELLKLVDETTSINLHFIR
                     QSHPRGLGDAVLQAKTFVGNEPFVVMLGDDLMDITNPNVKPLTKQLIDDYEETHAATI
                     AVMRVPHEDVSNYGIIAPQAKAVKGLYSVDTFVEKPQPQDAPSDLAIIGRYLLTPEIF
                     SILEKQEPGAGNEVQLTDAIDTLNKTQRVFAREFKGKRYDVGDKFGFMKTSLDYALKH
                     PQVKDDLKAYIIQLGKALEKTKP"
     gene            complement(32392..33408)
                     /locus_tag="ACF4ZO_000447"
     CDS             complement(32392..33408)
                     /locus_tag="ACF4ZO_000447"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009331 - glycerol-3-phosphate
                     dehydrogenase (FAD) complex [Evidence IEA];
                     GO_function: GO:0047952 - glycerol-3-phosphate
                     dehydrogenase [NAD(P)+] activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0046168 - glycerol-3-phosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HFD5486023.1"
                     /translation="MTKQKVAILGPGSWGTALSQVLNDNGHDVRLWGNIPDQIEEINT
                     KHTNRHYFKDIVLDKNITATLDLGQALSDVDAVLFVVPTKVTRLVARQVAAILDHKVV
                     VMHASKGLEPETHERLSTILEEVIPAHFRSEVVVVSGPSHAEETIVRDITLITAASKD
                     IEAAKYVQSLFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGYGDNAKAAVI
                     TRGLAEITRLGVKLGADPLTYSGLSGVGDLIVTGTSVHSRNWRAGAALGRGEKLEDIE
                     RNMGMVIEGIATTKVAYEIAQDLGVYMPITTAIYKSIYEGADIKESILGMMSNEFRSE
                     NEWH"
     gene            33706..34155
                     /locus_tag="ACF4ZO_000448"
     CDS             33706..34155
                     /locus_tag="ACF4ZO_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HFD5486024.1"
                     /translation="MSQVIGDLRELIHQIEQISDEIAKKYDVEHLAGPQGYVLVFLAK
                     HQNQEIFVKDIEKQLRISKSVASHLVKRMVKNGFINVMPSQVDKRYKQVVLAQVGRDK
                     LPLLRECRKDIEHYFLKEITKEELLTAKKVIEQLKQNMLTYKGDNDA"
     gene            34148..35854
                     /locus_tag="ACF4ZO_000449"
     CDS             34148..35854
                     /locus_tag="ACF4ZO_000449"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD5486025.1"
                     /translation="MLKDAILRYKWYALGSFFMVIGVVASSLLQPHYLKSVLSAVIQN
                     NQEKIYEVGKPLLIIALLGLMSGAINTVLAAKIAQGVSADMREKTFRKIQDFSYANIE
                     AFNAGNLVVRLTNDINQIQSLVMMMFQILFRLPILFIGAFIMAVQTFPQLWWVIVVMV
                     ILIALIMGLVMRQMGPRFGKFQRLMDKINHIAKENLRGVRVVKSFVQEQQQYTKFKET
                     SNDLLALNLSIGYGFSLMQPALMLVSYLAVYVSINVVSTMVETDPTVIGNIASFMTYM
                     MQIMFSIIMVGSMGMQVSRAFVSMARIRQILSTEPAMTFENEKEETISGSIVFDDVSF
                     TYPNDDEPTLKHISFAIEPGQMVGIVGATGSGKSTLAQLIPRLFDPQDGQILLGGKPI
                     KTLSQTTLRQSVSIVLQKAILFSGTIADNLRQGSAKADIDAMQKAAQIAQAKEFIDRM
                     NSRYESQVEERGSNLSGGQKQRLSIARGVINHPKILILDDSTSALDAKSEKRVQEALS
                     HKLEGTTTVIVAQKISSVVKADKILVLDQGQLIGEGTHAELVANNAIYREIYETQKGR
                     EE"
     gene            35857..37641
                     /locus_tag="ACF4ZO_000450"
     CDS             35857..37641
                     /locus_tag="ACF4ZO_000450"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD5486026.1"
                     /translation="MKTARFFWFYFKRYRFSFTVIAVAVILATYLQVKAPVFLGESLT
                     ELGKIGQAYYVAKMSGQTHFSPDLSAFNAVMFKLLMTYFFTVLANLIYSFLLTRVVSH
                     STNRMRKGLFGKLERLTVAFFDRHKDGEILSRFTSDLDNIQNSLNQSLVQVVTNIALY
                     IGLVWMMFRQDSRLALLTIASTPVALIFLVINIRLARKYTNIQQQEVSALNAFMDETI
                     SGQKAIIVQGVQEDTMTAFLKHNERVRQATFKRRLFSGQLFPVMNGMSLINTAIVIFV
                     GSTIVLSDKSMPAAAALGLVVTFVQYSQQYYQPMMQIASSWGELQLAFTGAHRIQEMF
                     DETEEVRPQNAPAFTSLKEAVAINHVDFGYLPGQKVLSDVSIVAPKGKMIAVVGPTGS
                     GKTTIMNLINRFYDVDAGSITFDGRDIRDYDLDSLRQKVGIVLQESVLFSGTITDNIR
                     FGDQTISQDMVETAARATHIHDFIMSLPKGYNTYVSDDDNVFSTGQKQLISIARTLLT
                     DPEVLILDEATSNVDTVTESKIQRAMEAIVAGRTSFVIAHRLKTILNADHIIVLKDGK
                     VIEQGNHHELLHQKGFYAELYHNQFVFE"
     gene            37759..38526
                     /locus_tag="ACF4ZO_000451"
     CDS             37759..38526
                     /locus_tag="ACF4ZO_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HFD5486027.1"
                     /translation="MIDLQEILANMNPNQKINYDRVMQQMAKVWEKESVRPSILMHVC
                     CAPCSTYTLEYLTQFADITVYFANSNIHPKDEYHRRAYVTQQFVSEFNAKTGNTVQFL
                     EADYVPNEYVRQVRGLEEEPEGGDRCRVCFDYRLDKTAQKAVELGFDYFASALTISPH
                     KNSQTINDVGIDVQKVYTTKYLPSDFKKNNGYRRSVEMCEEYDIYRQCYCGCVYAAKM
                     QGIDLVQVKKDAKAFMADKDLDNDFTHIRFSYRGDEM"
     gene            38636..39082
                     /locus_tag="ACF4ZO_000452"
     CDS             38636..39082
                     /locus_tag="ACF4ZO_000452"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HFD5486028.1"
                     /translation="MTKTRGFELVSSFTNPDLLPKRETTHAAGYDLSVAEAVTIAPGE
                     IKLVPTGVKAYMQDGEVLYLYDRSSNPRKKGIILINSVGVIDADYYGNEANEGHIFAQ
                     MQNITDHPVTLAVGERIVQGVFMPFLIADGDQARGERTGGFGSTGQ"
     gene            39163..40524
                     /gene="radA"
                     /locus_tag="ACF4ZO_000453"
     CDS             39163..40524
                     /gene="radA"
                     /locus_tag="ACF4ZO_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HFD5486029.1"
                     /translation="MAKKKATFICQECGYQSPKYLGRCPNCSAWSSFVEEVEVKEVKN
                     ARVSLAGEKSRPVKLKDVDNISYHRTQTDMSEFNRVLGGGVVPGSLILIGGDPGIGKS
                     TLLLQVSTQLANKGTVLYVSGEESAEQIKLRSERLGDIDNEFYLYAETNMQAIRTEIE
                     NIKPDFLIIDSIQTIMSPDITGVQGSVSQVREVTAELMQLAKTNNIATFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSAVVVTMEGSRPILAEVQSLVTPTVFGNARRTTTGLDFNRVSLI
                     MAVLEKRCGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKEKPTSPQEAFLGE
                     IGLTGEIRRVTRIEQRINEAAKLGFTKVYAPKNALQGIDIPQGIEVVGVTTVGQVLKA
                     VFS"
     gene            40713..41210
                     /locus_tag="ACF4ZO_000454"
     CDS             40713..41210
                     /locus_tag="ACF4ZO_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-class carbonic anhydrase"
                     /protein_id="HFD5486030.1"
                     /translation="MSYFEHFMAANQAYVALHGTAHLPLKPKTKVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFTNEGF
                     AKHIHEHLGVDVSGQDFLPFQDVEDSVREDMAKLRASSLIPDDVVINGAVYDVDTGKM
                     TQVME"
     gene            41341..42051
                     /locus_tag="ACF4ZO_000455"
     CDS             41341..42051
                     /locus_tag="ACF4ZO_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00266 family protein"
                     /protein_id="HFD5486031.1"
                     /translation="MVDNRMRFTIDRSMQFPLVEIDLEHGGSVYLQQGSMVYHTENVT
                     LNTKLNGKGSGLGKLVGAIGRSMVSGESMFITQAMSDGDGKLALAPNTPGQIVALELG
                     EKQYRLNDGAFLALDGSAQYKMERQNIGKALFGGQGGLFVMTTEGLGTLLANSFGSIK
                     KITLDGGTMTIDNAHVVAWSRELDYDIHLENGFMQSIGTGEGVINTFRGHGEIYIQSL
                     NLEQFAGTLKRYLPTSSN"
     gene            42232..43677
                     /gene="gltX"
                     /locus_tag="ACF4ZO_000456"
     CDS             42232..43677
                     /gene="gltX"
                     /locus_tag="ACF4ZO_000456"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004818 - glutamate-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HFD5486032.1"
                     /translation="MSKPIRVRYAPSPTGLLHIGNARTALFNYLYARRHGGTFIIRIE
                     DTDRKRHVEDGERSQLENLKWLGMDWDESPETHENYRQSERLALYQQYIDQLLAEGKA
                     YKSYVTEEELAAERERQEAAGETPRYINEFIGMSADEKAKYIAEREAAGIVPTVRLAV
                     NESGIYKWTDMVKGDIEFEGGNIGGDWVIQKKDGYPTYNFAVVVDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYM
                     PEAVFNFIALLGWNPGGEEEIFSREQLIALFDENRLSKSPAAFDQKKMDWMSNEYLKH
                     ADFETVYALCKPFLEEAGRLTEKAEKLVELYKPQLKSADEIIPLTDLFFSDFPELTEA
                     EKEVMAGETVSTVLQAFKAKLEAMSDEDFKPENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPNTIYLLGRDKSIEHIKNML"
     gene            44071..45417
                     /locus_tag="ACF4ZO_000457"
     CDS             44071..45417
                     /locus_tag="ACF4ZO_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HFD5486033.1"
                     /translation="MANSEYMFLLLSIIVYYMTKIYIFSFLSDITLPVWKQLTILALA
                     LFFNQFPYLSPLLIDPLLFLVVLRQETKQLFSLKALFLAVAPSVLVDLLSRFMGTIVI
                     PYLFLSSGIYLGHIIFDLLAYLLIFPSFAIINYMIGKDYKMICQSGYSKRSHNFYQTL
                     LIFVLVYYVDIFVILGFTDPFLHFHHSLFVPTPYKLLFLMFILLFVYLLSYFNHSSKE
                     YLKNELRREQQAYMTNLETYGKHLEKLYRDVRAFQSDYLSRIERLGQAIKSESITQIQ
                     DIYAQTVHEANDYWDDKHYNISKLRKINISSIKSLLSAKIISAEKSGIDLNVEVPDNI
                     KETYIPELDLLLLMSIFCDNAIEAALEAQQPHMSIAYFLLDDYQMFVVTNTTKKKVDI
                     NKIFEEGYSSKGSERGIGLSNAQRILKKYPYLSLRTKSFDKEFSQTLTMPKEEVDR"
     gene            45414..46697
                     /locus_tag="ACF4ZO_000458"
     CDS             45414..46697
                     /locus_tag="ACF4ZO_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HFD5486034.1"
                     /translation="MMVIYSMALFYATIFINSWVIFAKVSAIKLSWKRVSIIGISFVI
                     ANMIFDKVILIDQLFFIIVSLLSAPKKKLFEHMFNGFFTILIVELLFRVIGSFFLPAV
                     LGFSIGQINNNLKLLELCYLFVLPIFYLFSYIFSIDLSLIRFISEDKMKKWVFWMNTA
                     MFSYYFFAHFLVTVQSGFLALYFQYRSILVFIYLAIFIWVIVKLDRFAKDQLSQKLTQ
                     AQNERIAYLENYNQSIEQLYREIRTVKHDSENILISLKDSIDSGDIDLITRVYDTVIQ
                     QSTTSMMRTNYEISSLDNIKETVIRSIMNSKLLEAQYLGIELYIEIPDVIDHLPIKLI
                     DLIVLFTGLVDNAIETAKGSRRPFLSIAYFKQDNKQLFIIENSTKTNRVDIAKRFDAQ
                     QQNSAHFLTVLDSYPQITLSTKSDHYRLRQLLEMR"
     gene            46701..47441
                     /locus_tag="ACF4ZO_000459"
     CDS             46701..47441
                     /locus_tag="ACF4ZO_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFD5486035.1"
                     /translation="MMNIFILEDDFIQQTRIESIVVGILKETRIPCNQLEVFSTPQKL
                     FESIQERGDHQLYFLDIEIGEYTRCGLELAAAIRQKDPNAVIVFVTTHSEFAPISFKY
                     KVSALDFIDKAGGQKQFKEQIEECIRYTYDMMSSRESKDMFLFETPQTRLKLPYKDIL
                     YFATATTPHKVCLWTQTERLEFYGNLSEIQAVAPKLFLCHRSYLVNLDKVVRIDKSKQ
                     LLYFENGDSCMVSRLKMKCLFERWEALR"
     gene            47981..48340
                     /gene="rnpA"
                     /locus_tag="ACF4ZO_000460"
     CDS             47981..48340
                     /gene="rnpA"
                     /locus_tag="ACF4ZO_000460"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004526 - ribonuclease P activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HFD5486036.1"
                     /translation="MKKTYRVKREKDFQAIFKDGKSTANRKFVIYHLNRGQDHFRVGI
                     SVGKKIGNAVTRNAVKRKIRHVIMALGHQLKSEDFVVIARKGVESLEYQELQQNLHHV
                     LKLAQLLEKGFESEEKH"
     gene            48306..49133
                     /locus_tag="ACF4ZO_000461"
     CDS             48306..49133
                     /locus_tag="ACF4ZO_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0032977 - membrane insertase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YidC/Oxa1 family membrane protein insertase"
                     /protein_id="HFD5486037.1"
                     /translation="MRKVLRVKKNIKIARIVPLVLLLVACGRGEVTAQSSSGWDQLVY
                     LFARAIQWLSFDGSIGVGIILFTLTIRLMLMPLFNMQIKSSQKMQDIQPELRELQKKY
                     AGKDTQTRMKLAEESQALYKKYGVNPYASLLPLLIQMPVMIALFQALTRVSFLKTGTF
                     LWVELAQHDHLYLLPVLAAVFTFLSTWLTNLATKEKNVMMTVMIYVMPLMIFFMGFNL
                     ASGVVLYWTVSNAFQVVQLLLLNNPFKIIAERQRLANEEKERRLRERRARKKAMKRK"
     gene            49145..50059
                     /gene="jag"
                     /locus_tag="ACF4ZO_000462"
     CDS             49145..50059
                     /gene="jag"
                     /locus_tag="ACF4ZO_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding cell elongation regulator Jag/EloR"
                     /protein_id="HFD5486038.1"
                     /translation="MVLFTGKTVEEAIETGLQELGLSRLKAHIKVISKEKKGFLGFGK
                     KPAQVDIEGISDKTVYKADKKATRGVPEDINQKHAPAVNSADVEPEEIKATQKLEAED
                     TKVVPLMPEDSPAQTPSNLAETVTETKAQQPSIPVEESEVPQDAGNDGFSKDIEKAAQ
                     EVSDYVTKIIYEMDIEATVETSNNRRQINLQIETPEAGRVIGYHGKVLKSLQLLAQNF
                     LHDRYSKNFSVSLNVHDYVEHRTETLIDFTQKVAKRVLESGQDYTMDPMSNSERKIVH
                     KTVSSIEGVDSYSEGNDPNRYVVVSLQR"
     gene            50374..50508
                     /gene="rpmH"
                     /locus_tag="ACF4ZO_000463"
     CDS             50374..50508
                     /gene="rpmH"
                     /locus_tag="ACF4ZO_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HFD5486039.1"
                     /translation="MKRTYQPSKIRRQRKHGFRHRMSTKNGRRVLAARRRKGRKVLSA
                     "
     gene            50782..51486
                     /locus_tag="ACF4ZO_000464"
     CDS             50782..51486
                     /locus_tag="ACF4ZO_000464"
                     /EC_number="5.1.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009385 - N-acylmannosamine-6-phosphate
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006051 - N-acetylmannosamine metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019262 - N-acetylneuraminate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HFD5486040.1"
                     /translation="MPDKPTKEKLMEQLKGGIIVSCQALPGEPLYSETGGIMPLMAKA
                     AQEAGAVGIRANSVRDIKEIQAITDLPIIGIIKKDYPPQEPFITATMTEVDQLAALNI
                     AVIAMDCTKRDRHDGLDIASFIRQVKEKYPNQLLMADISTFDEGLVAHQAGIDFVGTT
                     LSGYTPYSRQEAGPDVALIEALCKAGIAVIAEGKIHSPEEAKKINDLGVAGIVVGGAI
                     TRPKEIAGRFIEALKS"
     gene            51535..52854
                     /locus_tag="ACF4ZO_000465"
     CDS             51535..52854
                     /locus_tag="ACF4ZO_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFD5486041.1"
                     /translation="MNMKKLASLAMLGASVLGLAACGGKSQKEAGASKSDTAKTEITW
                     WAFPVFTQEKAEDGVGTYEKKLIAAFEKANPEIKVKLETIDFTSGPEKITTAIEAGTA
                     PDVLFDAPGRIIQYGKNGKLADLNDLFTEEFTKDVNNDKLIQASKAGDTAYMYPISSA
                     PFYMALNKKMLKDAGVLDLVKEGWTTDDFEKVLKALKDKGYNPGSFFANGQGGDQGPR
                     AFFANLYSSHITDDKVTKYTTDDANSIKAMTKISNWIKDGLMMNGSQYDGSADIQNFA
                     NGQTSFTILWAPAQPGIQAKLLEASKVDYLEIPFPSDDGKPELEYLVNGFAVFNNKDE
                     QKVAASKTFIQFIADDKEWGPKNVVRTGAFPVRTSYGDLYKDKRMKKIAEWTKFYSPY
                     YNTIDGFTEMRTLWFPMVQAVSNGDEKPEDALKAFTEKANKTIKKTQ"
     gene            52959..53846
                     /locus_tag="ACF4ZO_000466"
     CDS             52959..53846
                     /locus_tag="ACF4ZO_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001260031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFD5486042.1"
                     /translation="MNVNKLKMRETLISYAFLAPVLVFFVIFVLIPMIMGFVTSFFNY
                     SMTDFTFVGFANYVRMFQDPIFMKSLINTLIIVIGSVPVVVFFSLFVAAKTYDKNVVA
                     RSFYRAVFFLPVVTGSVAVTVVWKWIYDPMSGILNYVLKYAHVIEQNISWLGDKHWAL
                     LAIIVILLTTSVGQPIILYIAAMGNIDNSLMEAARVDGATEFQVFWNIKWPSLLPTTL
                     YIAVITTINSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFKLSEYGYANTMGVFLAV
                     MIAIISFAQFKILGNDVEY"
     gene            53859..54689
                     /locus_tag="ACF4ZO_000467"
     CDS             53859..54689
                     /locus_tag="ACF4ZO_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017767339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFD5486043.1"
                     /translation="MTKKKLTASDILTTVMLCVLTILFIFPFYWIMTGAFKAQADTIM
                     IPPQWWPKAPTIENFKALVVQNPALKWLWNSIFISVATMFLVCGTSSLAGYALAKKRF
                     YGQRLLFSIFIAAMALPKQVVLVPLVRIVNFMGIHDTLAAVILPLVGWPFGVFLMKQF
                     SENIPTELLESAKIDGCGEIRTFFNVAFPIVKPGFAALAIFTFINTWNDYFMQLVMLT
                     SRENLTISLGVATMQAEMATNYGLIMAGAAMAAVPIVTVFLVFQKSFTQGITMGAVKG
                     "
     gene            54846..55508
                     /locus_tag="ACF4ZO_000468"
     CDS             54846..55508
                     /locus_tag="ACF4ZO_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HFD5486044.1"
                     /translation="MTSKKQGLLYSLFNLDSKWMRASAALFDLLVFNLLFVLSCLPLL
                     TIGVAKMALYASLLDWREGQVSQLFTTYSSYFKNYFKRGMRLGLIELLIMSICVLDLF
                     LIRNQSGLVFQGFKVLCIAVLFLVVILFLYAYPQAVRKELPLLILFKRSLLLAGIFFP
                     WTFAFLVVIGLLVFTLPLTLLTLFCGLSLLATMGISSLTYFYLLIMESLLRRFPLNND
                     IE"
     gene            55520..56434
                     /locus_tag="ACF4ZO_000469"
     CDS             55520..56434
                     /locus_tag="ACF4ZO_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HFD5486045.1"
                     /translation="MTDLTKYQGIIPAFYACYDDQGAISPERVRALTQYYIDKGVQGL
                     YINGSSGECIYQSVFDRQLVLENVMAVAKGKLTIINHVACNNTKDSIELAAHSERLGV
                     DAIAAIPPIYFRLPEYAVADYWNAISSAAPHTDFIIYNIPQLAGVALTPSLYKTMLAN
                     KRVIGVKNSSMPVQDIQTFCAIGGDDRIVFNGPDEQFLGGRLMGAAAGIGGTYGAMPE
                     LFLRLNQLIAHKDLEKAKALQYTINEIIGVLVSAHGNMYGVIKEVLRINEGLDIGSVR
                     SPLAELVEEDRVICQRAAALINQAKETF"
     gene            56456..57394
                     /locus_tag="ACF4ZO_000470"
     CDS             56456..57394
                     /locus_tag="ACF4ZO_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HFD5486046.1"
                     /translation="MKHYLAIDIGGTAIKYGLISETGDLLEKEEMATEAYKGGPSILE
                     KVKGLVKTYQDQMDLAGVAISSAGMVNPDEGEIFYAGPQIPNYAGTQFKKEIEETFGL
                     PCEVENDVNCAGLAEAISGSAKDYPVALCLTIGTGIGGCLLFNSQVFHGSSHSACEVG
                     YLHLSDGQFQDLASTTALVQEVALAYGDDISQWDGRRIFEQAKAGDAICIAAISKQVD
                     YLGQGIANICYVVNPNVVVLGGGIMAQKDYLADKLKTALDSYLVSSLAKKTQLKFASH
                     GNNAGILGAYYHFKQKNERSCSFITLEKIENNLASS"
     gene            complement(57505..58335)
                     /locus_tag="ACF4ZO_000471"
     CDS             complement(57505..58335)
                     /locus_tag="ACF4ZO_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFD5486047.1"
                     /translation="MPKNHRLITKIEASLEHMTSLEKGIAHFFITTDLTPQELTASEI
                     VKRLHISQAALTRFAKKCGFTGYRAFAFDYLHSLQESQETFQSIHLELTKRVLMDYDA
                     LINKTYELVNEEKLLNLAKLIDASERVYFFGKGSSGLVAREMKLRFMRLGLICDAYSD
                     TDGFTWANSLVNENCLVFGFSLSGKTNSVITALHQASQRGAKTVLLTTDNQTEFDDSL
                     DIIPVSSTHQLHYGNRVSPQFPLLIMMDIIYAYVLAIDKPHKEKIFKNTIIDKENNDL
                     "
     gene            58620..59411
                     /locus_tag="ACF4ZO_000472"
     CDS             58620..59411
                     /locus_tag="ACF4ZO_000472"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HFD5486048.1"
                     /translation="MTNKVEKLTIFDTHTHLNVAEFQGHEAEELALAQEMGVAYHNVV
                     GFDQATISGALALADQYPNVYATIGWHPTEAGSYSEAVEESIVSQLSHPKVIALGEIG
                     LDYHWMEDPKEVQIEVFKRQMQLAKDHDLPFVVHTRDALEDTYEVIKAAGVGPRGGIM
                     HSYSGSLEMAERFIELGMMISFSGVVTFKKALDIQEAAQHLPLDKILVETDAPYLTPV
                     PKRGKQNHTAYTRYVVDKIAELRGMTVEEVAKATTANAKRVFKLD"
     gene            59383..59973
                     /gene="rnmV"
                     /locus_tag="ACF4ZO_000473"
     CDS             59383..59973
                     /gene="rnmV"
                     /locus_tag="ACF4ZO_000473"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043822 - ribonuclease M5 activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HFD5486049.1"
                     /translation="MQRGYSSLTEKINIQEVLVVEGKDDTANLRRFYEVDTYETRGSA
                     ITEEDLERINRLNDLRGVIVLTDPDYNGERIRKLIMAAVPTARHVFLNRNEAVPSSKS
                     KGRSLGVEHARFEDLQKALAHVTQQYDDESYFDIRQTDLIRLGLLMASDSRKRREYLG
                     EKLRIGYANGKQLLKRLELFGITLAEVEEVMETYGE"
     gene            60087..60959
                     /gene="rsmA"
                     /locus_tag="ACF4ZO_000474"
     CDS             60087..60959
                     /gene="rsmA"
                     /locus_tag="ACF4ZO_000474"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000179 - rRNA
                     (adenine-N6,N6-)-dimethyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HFD5486050.1"
                     /translation="MRIADYSVTKAVLDRHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DQNVNVIEIGPGIGALTEFLAENAAEVMAFEIDDRLVPILADTLRDFDNVQVVNQDIL
                     KADLQTQIKQFKNPDLPIKVVANLPYYITTPILMHLIESKIPFQEFVVMMQREVADRI
                     SAEPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRDQPLIEIKD
                     EDFFFRVSRLSFVHRRKTLWNNLTSHFGKSEDIKTKLEKGLALADIKPSIRGEALSIQ
                     DFGKLADALKEVGL"
     gene            61384..62256
                     /gene="rsgA"
                     /locus_tag="ACF4ZO_000475"
     CDS             61384..62256
                     /gene="rsgA"
                     /locus_tag="ACF4ZO_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HFD5486051.1"
                     /translation="MQGKIIKSLAGFYYVESEGQVYQTRARGNFRKRGETPYVGDIVD
                     FSAEDNSEGYILAIHPRKNSLVRPPIVNIDQAVVIMSAKEPEFNSNLLDRFLILLEHK
                     AIHPVVYISKMDLLDSPEEIKAIGRQYQAIGYNFVTSLEELLPLLADKITVFMGQTGV
                     GKSTLLNRIAPELALETGEISDSLGRGRHTTRAVSFYNTHGGKIADTPGFSSLDYDIA
                     NAEDLNEAFPELRRLSHKCKFRSCTHTHEPKCAVKAALETGELWPVRYEHYLQFLSEI
                     ENRRETYKKVIKRK"
     gene            62266..62928
                     /gene="rpe"
                     /locus_tag="ACF4ZO_000476"
     CDS             62266..62928
                     /gene="rpe"
                     /locus_tag="ACF4ZO_000476"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004750 - D-ribulose-phosphate 3-epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HFD5486052.1"
                     /translation="MSTLKIAPSILAADYANFASELARIEETDAEYVHIDIMDGQFVP
                     NISFGADVVASMRKHSKLVFDCHLMVVDPERYVEAFAQAGADIMTIHTESTRHIHGAL
                     QKIKAAGMKAGVVINPGTPATALEPLLDLVDQVLIMTVNPGFGGQAFIPECLEKVATV
                     AKWRDEKGLSFDIEVDGGVDNKTIRACYEAGANVFVAGSYLFKASDLVSQVQTLRTAL
                     NV"
     gene            62921..63553
                     /locus_tag="ACF4ZO_000477"
     CDS             62921..63553
                     /locus_tag="ACF4ZO_000477"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004788 - thiamine diphosphokinase
                     activity [Evidence IEA];
                     GO_process: GO:0006772 - thiamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HFD5486053.1"
                     /translation="MSKVALFAGGDLSYISRDFDYFVGIDRGSLFLLENGLPLNMAVG
                     DFDSVSQKAFTDIKEKAELFITAHPEKSDTDTELALKEVFARFPEAEVTIFGAFGGRM
                     DHLLSNIFLPSDPGIAPFMAQIALRDQQNMITYRPAGQHLIHQEEGMTYVAFMAEGEA
                     DLTITGAKFELTQDNFFKKKIYSSNAFIHQPITVSLPSGYLIIIQSKDWS"
     gene            63555..64826
                     /gene="rmuC"
                     /locus_tag="ACF4ZO_000478"
     CDS             63555..64826
                     /gene="rmuC"
                     /locus_tag="ACF4ZO_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HFD5486054.1"
                     /translation="MDLILFLLVLVLLGLGAYLLFKVNGLQHQLAQTLEGNADNLSDQ
                     MTYQLDTANKQQLLELTQLMNRQQADLYQQLTDIRDVLHRSLSDSRDRSDKRLEEINQ
                     QVNQSLKNMQESNEKRLEEMRQIVEEKLEETLKNRLHASFDSVSKQLESVNKGLGEMR
                     SVAQDVGTLNKVLSNTKTRGILGELQLGQIIEDIMTSSQYEREFVTVSGSSERVEYAI
                     KLPGNGQGGYIYLPIDSKFPLEDYYRLEDAYEVGDKLAIEASRKALLAAIKRFAKDIH
                     KKYLNPPETTNFGVMFLPTEGLYSEVVRNAAFFDSLRREENIVVAGPSTLSALLNSLS
                     VGFKTLNIQKNADDISKILGNVKLEFDKFGGLLAKAQKQMNTANNTLDQLISTRTNAI
                     VRALNTVETYQDQATKSLLNMPLLEEENNEN"
     gene            64816..>64917
                     /locus_tag="ACF4ZO_000479"
     CDS             64816..>64917
                     /locus_tag="ACF4ZO_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771182.1"
                     /note="catalyzes the exonucleic cleavage of mRNA yielding
                     nucleioside 5'-phosphates; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HFD5486055.1"
                     /translation="MKINQMKKDQLFEGFYLIKSAEVRKTRAGKDFIS"
BASE COUNT        19404 a        11861 c        13950 g        19702 t
ORIGIN      
        1 agtagagtcc attttgtcac atccagcaac gatgtctcat gcttgtttat catcacaagc
       61 gcggttggaa caaggggttg ttgatggttt gctgcgcttg tcttgtggtg ttgaaaatat
      121 cgaagattta ttggccgatt ttgagcaagc acttgctttt taagtctatt tgtccagatt
      181 ggctctgttt acagagcaag tctggctttt ttattagctt tttgtgagga tggttgatgc
      241 taaagcaggg tttaaaaata gctaatcgtc tgaagtctca aaagccaagg tgctagccat
      301 gtcttgacca ttcctaaaag cttcatctca tgctataata agaagactag attttttaca
      361 tgggagattt cacatgacat tttacgatca caccgctatt gaacccaaat ggcaagcctt
      421 ttgggcagat aatcatacct ttaaaacagg aacagacgca tcaaaaccta agttttatgc
      481 cctagatatg ttcccatacc catcaggagc tggtctccac gttggtcacc cagaaggcta
      541 tacagcaact gatattctca gccgtttcaa acgtgcccaa ggtcacaatg tcctccaccc
      601 aatgggttgg gatgcctttg gacttcctgc tgagcagtac gctatggata ctggtaatga
      661 cccagccgag tttacagctg aaaacatcgc taacttcaaa cgccagatta atgctcttgg
      721 tttctcatac gactgggatc gtgaagttaa cacaactgac cctaactact acaagtggac
      781 gcagtggatc tttaccaagc tttatgaaaa aggtctagcc tacgaagctg aagttcccgt
      841 taactgggtt gaagaattgg gaacagctat cgccaacgaa gaggttcttc cagatgggac
      901 atcagagcgt ggcggctacc cagttgtcag aaaacccatg cgccaatgga tgctcaaaat
      961 cacggcctat gcagagcgcc tgctagaaga cttggaagaa gttgactggc cagaatcaat
     1021 caaggacatg caacgcaact ggattggtaa atcaactggt gctaatgtaa ccttcaaggt
     1081 taaggataca gataaggact tcactgtctt cacaacacgt cctgacacgc tttttggtgc
     1141 aacttacgcg gttcttgctc ctgagcatgc cttggttgat gctattacga cagctgacca
     1201 ggcagaagcc gtggctgact acaaacgtca agcaagtctc aaatcagacc ttgctcgtac
     1261 agaccttgcc aaagaaaaaa ctggtgtctg gacaggtagc tacgctatta acccagttaa
     1321 tggtaacgaa atgccagttt ggattgcgga ctatgtcctt gctagctacg gtactggtgc
     1381 tatcatggct gttccagccc acgatgaacg tgactgggaa ttcgcaaaac aatttaacct
     1441 agacatcatc cctgttcttg aaggtggtaa tgttgaagag gctgccttta cagaagacgg
     1501 tcttcacatc aactcaggct tcctagatgg tctcgataaa gcgtcagcta ttgccaaaat
     1561 ggtcgaatgg cttgaagcag aaggcgtcgg taatgagaaa gtgacttacc gtctccgtga
     1621 ctggctcttt agccgtcaac gttattgggg tgagccaatc ccaatcatcc actgggaaga
     1681 tgggacatca acagcggttc ctgagagtga gttgccactg gttcttccag taactaagga
     1741 tattcgtcct tcaggtactg gtgagagccc acttgctaac gtgacagact ggttggaagt
     1801 gactcgtgaa gatggtgtta aaggtcgtcg tgagactaac accatgccac aatgggcagg
     1861 ttcaagctgg tattatcttc gttacatcga tccacacaac accgaaaaac tggctgacga
     1921 ggaactcctc aaacaatggt tgccagttga tatctatgtc ggtggtgcag agcatgccgt
     1981 gcttcacctt ctctacgctc gcttctggca caaggttctt tacgatctcg gtgtcgtacc
     2041 aaccaaagag ccattccaaa aactctttaa ccaagggatg attttgggaa caagctaccg
     2101 cgacagccga ggagcgcttg tagcgactga caaggttgaa aaacgtgatg gcagcttctt
     2161 ccatgtggaa actggtgaag agcttgaaca agcaccagct aagatgtcta aatcacttaa
     2221 gaacgttgtc aacccagatg atgttgttga acagtacggt gctgacactc ttcgtgttta
     2281 cgagatgttc atgggaccac ttgacgcttc catcgcttgg tctgaagaag gtcttgaagg
     2341 ctcacgtaag ttcttggacc gtgtttaccg tttgatcaca actaaagaga tcactgagga
     2401 aaatagcgga gctcttgaca aggtttacaa cgaaaccgtt aaggccgtta ctgagcaagt
     2461 tgaccaaatg aaattcaaca cagctatcgc tcaactcatg gtctttgtca acgcagccaa
     2521 caaggaagac aaactcttta gcgactatgc caaaggcttt gttcaattga ttgcaccatt
     2581 tgcaccgcac ttaggtgagg aactctggca agccttgaca gcctcaggtg agtcaatctc
     2641 ttacgtgcca tggccaagtt atgataaaag caaattggtt gaaaacgatg tggaaatcgt
     2701 tgtccaaatc aaaggtaagg tcaaagctaa acttgtcgtt gctaaagacc tttcacgcga
     2761 agaattgcaa gaagttgccc ttgctaacga aaaagtccaa gccgaaatca caggcaaaga
     2821 catcatcaaa gtcatcgcag taccaaacaa actcgttaat attgttatca aatagtttga
     2881 ggtgacacag cccttcagtg gttatttgcg tcacgtcaca gttaatgcca aagagctgat
     2941 ctattcaaaa agcaacttat ctagaaaaac cacaagaacg aaggttcttg tggtttttaa
     3001 tcgttgttta ggggtatttt ctccttatta ttaagtgtag ttaaatttta aaataagtta
     3061 acttaagtct aatattgaac acttctttgt gtgatagttg gtctttttta aaacgctttc
     3121 attacctata atgaacatat aaacacttta tctttattaa ctttgaaaag aggtagttct
     3181 tatggaaatg ctcctagctc ccctaaactg gttctcgcaa aatattttgc aaaacccagc
     3241 gttctttgta ggtcttttgg ttttaatcgg gtatttactc cttaaaaaac ccatttatga
     3301 agtctttgct ggttttgtaa aggctaccgt tggttacttg attttgaacg ttggagcagg
     3361 cggtcttgta acgacttttc gtccgatctt ggttgctctt gccaagaaat ttgaattgaa
     3421 agccgccgtt attgatcctt attttggttt ggctgctgct aatactaagt tagaagagat
     3481 gggcttcatc agtgttgcta cgacagctct cctgattgga tttggggtca acattctttt
     3541 ggttgcactt cgcaaggtca ctaaagttcg tacccttttc atcacaggtc acatcatggt
     3601 ccaacaggca gcgacgattt cggtctttgt ccttctttta atccctcaat tccaaaatgc
     3661 ctttggtgcg tgggcagttg gtatcatctg tggtctttac tgggcagtca gctcaaacat
     3721 gaccgttgaa gcaactcaac gccttacagg tggcggtggg tttgcgattg gtcaccaaca
     3781 acaatttgcg atttggtttg tggataaggt tgcaccgttc tttggtaaaa aagaagaaaa
     3841 ccttgataac ctaaaattac caaccttctt aaacattttc catgatactg ttgttgcgtc
     3901 agcaactttg atgttggtct ttttcggagc tatcttggct gtccttggtc cagacattat
     3961 gtctgatgtg gacttaatcg gacctggagc attcaaccca gctaagcaag ctttcttcat
     4021 gtatattttg caaacctctc tcaccttctc agtttatctc tttatcttga tgcagggtgt
     4081 tcgcatgttt gtttctgaat tgaccaatgc ctttcaaggg atctcaagca aattgcttcc
     4141 agggtcattc ccagcggttg acgttgcagc ttcctatggc tttggttctt caaatgcggt
     4201 gctttcagga tttgcctttg gtttgattgg tcaattaatc accattgctc ttcttgttat
     4261 ctttaaaaat ccaatcttaa ttatcacagg attcgttccc gtattctttg ataatgcggc
     4321 aattgcggtt tatgcagata aacgtggtgg ctggaaagca gcggtagctc tatcatttat
     4381 ttcaggtatt ttgcaagttg cacttggtgc tgttgctgta ggtcttttag gacttacagg
     4441 tggttatcac ggtaatatcg acttggttct tccatggtta ccatttgggt acctcttcaa
     4501 attccttggt attgcagggt atgtgcttgt ttgcatcttc ttacttgcca ttccacaatt
     4561 gcaattcgca aaagctaagg acaaagaagc ttattaccgt ggggaagctc aataacactg
     4621 catcttaaga aatagctctg ctattttaac aaaacaataa taaaacattt tcggaggaaa
     4681 aaacaatggt taaagtctta acagcatgtg gcaatggtat ggggtcatct atggtgatca
     4741 aaatgaaagt tgaaaatgcg cttcgtcaac ttggtgtgac agatattcag tcagcttctt
     4801 gctcagttgg tgaagctaaa ggtctagctt ctggctatga cattgtagtg gcatcaaacc
     4861 acttgattca tgagcttgat ggtcgtacca aaggccactt ggttggtctt gataacctga
     4921 tggatgataa tgaaattaaa accaaactac aagaagtgct ataagctaat tctgaatcaa
     4981 aacgaaggag ttgtgacgaa ggttttcagc tctttctctt tagtaggata aaactagtaa
     5041 aaatggtgtg tgttgcaaag caagacacta gaaagagata gtttttatga atttaaaaca
     5101 agcctttatt gacaacaact ccatccgatt ggggctaagt gctgatactt ggcaagaggc
     5161 tgttcaatta gctgttcaac ctttgattga tagcaaagca gtgacgtcag cttactacga
     5221 cgccatcatt gcatcaacag aaaaatacgg cccttattat gtgttgatgc caggtatggc
     5281 tatgccccat gcagaagcag gtttaggcgt taatcgcaat gcatttgctt tgattacact
     5341 aacaaaacca gttaccttct cagatggtaa agaggtttct gttcttttga cgttggccgc
     5401 tacagaccct tctattcaca caacagtggc tatcccacaa attgtggcct tgtttgaact
     5461 agataacgcc attgaacgct tggtggcctg ccaaagtcct aaagaggtcc tagaaatggt
     5521 agaagaatct aaagatagtc cttacttaga aggtatggac ttgaatgctt aagctttcct
     5581 tacacaggat actaacgaat gatggaaagg ataagaactc ttaaccagtt tgcacggtgg
     5641 ctaagagttt taggaaaaag agatgacaca tattccaaat ttacaagttg ctttagacca
     5701 ttctgactta cagggggctg ttaaagcagc cgttgctgtg ggtcacgaag tagatgtgat
     5761 tgaagctggt accgtttgtt tgcttcaagt gggaagcgag ttggttgagg tattacgcag
     5821 cctcttccca gagaaaatta tcgtagcaga taccaaatgt gctgacgctg gcggtacggt
     5881 cgctaaaaac aatgcgaaac gtggtgctga ctggatgacc tgcatttgct gtgcgacgat
     5941 tccaaccatg gaagcagccc tcaaggctat gaaagaagag cgcggtgacc gtggggaaat
     6001 tcaaatcgaa ctttatggtg attggactta tgagcaagct caattatggc ttgacgctgg
     6061 gatttcccaa gcgatttacc accaatctcg tgatgccctt cttgctggag aaacttgggg
     6121 tgaaaaagac cttaacaagg tgaaaacatt gattgacatg ggcttccgcg tgtcagtaac
     6181 tggtgggctt gatgtagaca ctttgaaact ttttgaaggg gttgatgtct ttacctttat
     6241 cgcagggcga ggcattactg aagcagaaga tcctgctgca gcggcgcgtg ccttcaaaga
     6301 tgaaatcaaa cgtatctggg ggtaacttta tggcgcgtcc tattggtatt tatgaaaaag
     6361 caacgccaaa acagtttacc tggcgtgaac gcttgcaatt tgcaaaagac ttaggttttg
     6421 attttgtgga aatgtctgtt gatgaatcag atgctcgctt agcgcgctta gagtggacta
     6481 aggaagaacg gcttgattta gtgaaagcca tttatgaaac aggcattcgc atcccgacca
     6541 tttgtttttc tggtcataga cgttacccac taggctcaaa tgatcctgct attgaagcca
     6601 agtcccttaa actgatgaaa caatgtattg aattggcaca ggacttaggc gttcgtacca
     6661 ttcaattagc tggttatgac gtttactatg aagaaaaatc gcctgaaacc cgtgctcgtt
     6721 ttatcaaaaa cttgagacaa tcttgtgact gggccgaaga agcccaagtg atgctttcta
     6781 ttgagattat ggatgaccct tttatcaact ctattgaaaa atacttggca gttgaaaaag
     6841 agattgactc gccttatctc tttgtttatc ctgatgcagg caatgtttct gcctggcata
     6901 atgatttgtg gagtgaattt tacaatggtc acaagtccat tgcagccctc cacttgaaag
     6961 atacttatgc tgtcacggaa acctcaaaag ggcagtttcg tgatgtgcca tttggtcaag
     7021 gttgtgtgga ctggcaagag ctgtttgcgg tcctcaagaa aaccaactac aatgggcctt
     7081 ttttgattga aatgtggtca gaaaattgtg acacggtgga ggaaacaaaa gctgctatca
     7141 aagaagctca ggacttcctt tacccactta ttgagaaagc ggggttggca taatatggcg
     7201 aaaaacttgc aagaaatgcg tgaacgtgtc tgtgcggcta acaagtctct accacaacac
     7261 ggtcttgtca aatttacgtg gggcaatgtc tctgaagttt gtcgtgaatt aggacgtatt
     7321 gtcatcaagc cttctggggt ggactacgac ctcttgacac cagaaaacat ggttgttaca
     7381 gaccttgatg ggaatgtggt cgaaggtgat ttgaaccctt cttcagatct gccaacccat
     7441 gtggaacttt ataaagcttg gccagaagtg ggcggtattg tccacactca ctccacagaa
     7501 gctgttggtt gggctcaggc aggtcgtgat attccgtttt atgggactac gcatgctgac
     7561 tacttctatg gaccagttcc gtgtgctcgt tctctcacaa aagcagaagt tgatggggct
     7621 tacgagcaag aaactggcaa cgtgatttta gaagagttta gcaagcgagg cttagatcct
     7681 atggcggttc caggaatcgt ggttcgcaat catggcccat ttacgtgggg gaaaacccca
     7741 gagcaagccg tttaccactc ggttgtctta gaagaagtgg ctaggatgaa tcgcttgaca
     7801 gaacaaatca atccacgcgt agagccagcg ccacgataca ttatggataa gcattatttg
     7861 cgtaaacatg gcccaaatgc ttattacggt caaaaatgag gtcacgatat ggcttattag
     7921 cacaggttct cactagaagc cagaaagttc aaagttttgt taatcattgt ttgggcaagt
     7981 ccttttgact tgtccttttc gatgaactat ttaaacgcca atgagcacaa actggatgaa
     8041 tcgtatgttg tggagttctt agagaccaga tataaggtgt tggatcagtt gaggtgatta
     8101 gctcgaatca tattaagcga atcttattat ggtgagtttt tcaaaacttg gctgcgcagt
     8161 cactgaaatc atgataaaat aagcaaggat ggattttcag agaggaggtt tgtaaacatg
     8221 atgattttag ataaaaagag ttatgacttg ctgtcttatt tacttaaact agaaacacct
     8281 gagacagtta tggccatttc tcatgcttta aatcagtcac gtcgtaaagt ttattaccag
     8341 cttgacaaaa ttaatcaggc tttgccaaag ggagtagatc agattatctc ttatcctaga
     8401 cttggcattc ttttaacggc ggatcaaaaa gctgcttgtc gcttattatt agaagaagtg
     8461 actgattata attatgtcat gaaaagtgat gagcgcagac gcctatcctc gatttatatt
     8521 gcggtttcca ctgagcgcgt gaccatcgat aaactgatgc agatcaatga tgtgtctcgt
     8581 aacacgattt taaacgacct gactgagtta agggaagaac tggaagacaa acaatacaag
     8641 attcagcttc atgcgacaaa ggctagggga tattattttg gttgtcatcc aatggctctt
     8701 attcaatacc tgtacaaatt gttagtggac gtttaccaag gtggcaatac tagctttatt
     8761 gatatattca accgtaaact ctcagagata caaggcttat cggtttattt ttctaaagat
     8821 attttgacct attttcatga gtatctcttt ttatctcaag ctagtttagg aaagacaatt
     8881 aatacccaag atagccaatt catgttgcag attttacctt tcatgctttt aagttatcgt
     8941 aatatgcgtc ttgattcaga aacaaagtct gctcttaaac aagaatttca tttgatttgg
     9001 aaacgtaaag aatatcacat tgctcaggat ttagctagag agctttacca taattttaag
     9061 cttcatttgg atgatatcga agttagtatg gtagcgatgt tgatgttgtc ttttcgaaaa
     9121 gatcaagatc atcacgtgga aagtcaagat tatgacgaca tgcgagcaac cattagtcac
     9181 tttattgacc agttggagag ccgttatcag ttacatttca cgcataaaca ggatttgctg
     9241 aagcagttga cgacccactg taaggcgctc gtttaccgta aagcttatgg gattttttta
     9301 gttaatccct taacagacca tattaaagaa aaatacgaag aattgtttgc tatgactcaa
     9361 tcttgtgcca ctattttgga acaagattgg acgattagct tgacagacga tgatattgcc
     9421 tacttgacta tccatcttgg gggagagctg cgtcacaata atacagagca agaaaagacc
     9481 aaactcgtta ttgtttcaga tgatgggata ggcattcaaa agttattgtt caaacagtgt
     9541 caaaggtatc tagcaaatgg tcagattgaa gctgttttta cgacagaaca gtatcagagt
     9601 gtttacgatc ttttagcagt cgatatgatt gttgctacta cagatacgct aaagactaaa
     9661 atcccgatgc ttattgttaa ccctatttta agtgacgatg atatcatcaa attgatacgc
     9721 ttttcaaagc aaggacgctt gagtgagcat tcccgctttt ctacagagct cacaaaagct
     9781 attgaagctg ttgtaaaaga tgaatcagat cgttatgcct tggtttctaa aattgaaaaa
     9841 ctcattcatc gcgagctgct atgagtaagt gttaagtcgt caaagtacct cagttttcta
     9901 tgacatagaa aaatataact gaggttttta atatagcttt gaatacagta ttgatgcgag
     9961 atacagtgtg caaaatgaga cagtattaga ctgagctaat gaaaaagtca gtccactttt
    10021 gaacacagat ctgtgtgaca cttggtcttt ttatcattga caagaaagtc tatacttaaa
    10081 gtatagaaac gaagaacaaa ttcggaggaa accctaatga ctaaagtaca agatattaca
    10141 cgtgaatcat ggatccttaa cacgtttcca gaatggggaa catggttaaa tgaagaaatc
    10201 gagcaagaag tcgtgccagc tgacaacttt gcgatgtggt ggttaggaaa ctgtggtatc
    10261 tggattaaga caccaggcgg tgctaatgtt gtcatggact tatggtcaaa tcgtgggaaa
    10321 gcgaccaagc aagttaagga tatggttcgt ggacatcaaa tggctaatat ggcaggagct
    10381 cgtaaattac agcccaatct tagggcccaa ccaatggtga ttgatccatt tatgattaat
    10441 gagttggatt attatttggt ttctcattat catagtgacc acatcgatat caatactgcg
    10501 gcagccatta tcaataaccc aaaacttaat catgttaaat ttgtaggacc ttatgaatgt
    10561 ggtgaagttt ggaaaaattg gggtgtgcca aaagatcgta ttatgatctt aaagccaggt
    10621 gatagctttg aattcaaaga tattaagatc accgctgtag agtcgtttga ccgcacctgt
    10681 ctggtaactc tcccaataca aggagctgat gctcaagatg gtgatttagc aggtttagct
    10741 atcacagatg atgacatggc tcgcaaagct gttaactata tttttgaaac accaggtggt
    10801 accatctatc atggtgcgga ttctcatttt tcgaactact ttgctaaaca tggacgtgat
    10861 tatgatattg acgttgtgtt aaataactat ggggaaaacc caattggaat tcaagacaag
    10921 atgacttctg ttgaccttct tcgtatggca gaaaatctcc gtgctaaagt cgttatccca
    10981 gttcattatg acatttggtc aaactttatg gcatcaacag atgaaatcct tgaactgtgg
    11041 aaaatgcgca aagaacgtct ccaatacgat ttccatccct ttatctggga ggttggtggc
    11101 aagtacacct atccacaaga ccaaaatcgt atcgaatacc atcatcctcg tggatttgat
    11161 gactgcttct tagaagattc taatatccaa tttaaagctt tactataagc aacaccctac
    11221 tcacctaaga tgatagtgcc tgattaagct aactcgcttc ataggacact gtcttaggtg
    11281 agttttttgg agagatgagc aaatgtttaa gagtcaccgt ggtcgttatt tacgatggcc
    11341 gcaaaagaga tattataggt aaaagaagga tttctaatgt aacaatagcc taatcagcaa
    11401 agaaatagtc atcagttgtg ataaaaaatt gtactggtta aaagaccata cctaaaagaa
    11461 tgaaagcgat cacctatcat tgtggcatta ccagatcgag ttattgtcct tgacaaaaag
    11521 tgaccacacg tgataatata gttatgttct gtttcggcag attctttttt taagtaaaaa
    11581 agtgaccaca cgtttattaa ttgtgtagag ctactttgtt aaatattggc taatatttcg
    11641 ccaaagctat gtcattattt cacatgataa acgattacct aggagaaaaa acgaatggaa
    11701 acaattttag aagtcaaaca tctcagtaaa atttttggca aaaaacaaaa agcagctctt
    11761 gagatggtaa agactggcaa aaataagagt gagattttta agaaaacagg cgctactgta
    11821 ggtgtctatg acgctagttt tgaggtcaaa aaaggtgaaa tctttgttat tatggggcta
    11881 tcaggaagtg ggaaatcaac ccttgtccgc atgctaaatc gtttgattga accttcagca
    11941 ggatctatct tgctggaagg taaagacatc tcaaccatgt cagcagatca gctgcgtgag
    12001 gtgcgccgcc atgacattaa catggttttc caaagctttg ccctctttcc tcataaaacc
    12061 attttggaaa ataccgaatt tggtttggaa ttacgtggcg ttcccaaaga agaacgccag
    12121 cgattggcag aaaaagccct tgataattca ggcctattag attttaaaga ccagtaccca
    12181 aaccaactat ctggtgggat gcagcagcgt gtcggcctag cccgtgcgct agctaatagc
    12241 cctaaaattc tcttaatgga cgaggcattc tcagcgcttg atcctttgat tcgtcgtgag
    12301 atgcaagatg aattacttga tttgcaagac agcatgaaac aaaccatcat ctttatcagt
    12361 catgacttga atgaagcctt gcggattggt gatcggattg ctttgatgaa agacggacaa
    12421 attatgcaaa ttggtactgg tgaggaaatc ttgactaacc cagccaatga gtttgtgcgt
    12481 gaattcgttg aggatgtgga ccgttctaaa gtcttgacag cacaaaatat catgatcaaa
    12541 ccgttaacaa ctactgttga attagatgga cctcaagttg ccttgaaccg tatgcacaac
    12601 gaagaggtgt ctatgttgat ggcgacgaat cgccgccgcc aattagtcgg tagtttgacg
    12661 gccgatgccg ccatagaggc gcgcaaaaaa gggttaccgc tatcagaagt gattgatcgc
    12721 gatgtgagaa ctgtctcaaa agatactatt attacagata ttttgcctct tatctatgat
    12781 tcatctgctc cgattgcagt gacagatgat aataatcgtc tgttaggtgt cattattcga
    12841 ggacgagtga ttgaagcctt ggctaatatc tcagacgaag accttaacta aaaggagtga
    12901 tgcattttgg aaacgatatt acaaacaaaa ttaccagtag ctcaactggt ggagcagcta
    12961 acggagtggc taactaaaac tttctcaggt ctatttgata ttatgcaagt agttggtagc
    13021 tttttgatgg attggatgac caaaacactt ttatttatcc acccgttact ttttattgtt
    13081 ctagtaacag cagggatgtt tttccttgct aagaaaaaat ggcctttgcc aacctttacc
    13141 ttgttaggat tgctctttat ttacaatcaa gggttatgga agcagctaat gaataccttt
    13201 actctggtgt tagtagctag tttgatttcg gtacttattg gtattccgct ggggatttgg
    13261 atggctaaaa atgccactgt ccgtcagatt gtgaatccta ttttggactt tatgcaaacc
    13321 atgccggctt ttgtttactt gattcctgcc gttgcctttt ttggtattgg tatggtgcct
    13381 ggagtatttg cttcagtcat ctttgcctta ccaccaacgg ttcgttttac aaatttggcc
    13441 attcgtgaca ttccaacaga attgattgag gcctcagatg cctttgggtc aactgggaaa
    13501 caaaagctct ttaaagttga attgccttta gctaaaaata ctattatggc aggtgttaat
    13561 cagaccatga tgttagccct ttccatggta gtaacaggct ccatgattgg tgctcccggt
    13621 ttaggacgtg aagtcttgtc agcccttcaa cacgctgata ttggtagtgg atttgtcagt
    13681 ggtcttgcct tggttatctt ggcgattgtg cttgaccgta tgacacagtt gttcaatagt
    13741 aaacctcaag aaaaagccaa agctggcaaa accaataaat ggattggtct agcagccctt
    13801 gctatctttt tgatagctgc tttaggacgc ggtattatga ctatggcttc gggtatggca
    13861 gataagggtg aaactgttaa catcgcttac gtgcagtggg attctgaggt tgcctcaact
    13921 catgtgattg cagaagtttt gaaaaacgaa ggttaccatg tgaccttgac tccgcttgac
    13981 aatgctgtca tgtggcaaac cgttgctaat ggcaacgctg acttttcaac tagtgcttgg
    14041 ttgccagtca cccatggcca acaatatcag aaatacaagt caaaattaga tgatttaggg
    14101 cctaacctaa aagggaccaa acttggttta gctgttccta aatacatgac agatgttaat
    14161 agtattgagg atttaagcaa acaagccgat caaaaaatca cagggatcga accaggtgca
    14221 ggtatcatgg cagcagccaa aaagactcta aaagagtatc ataatctatc tagttgggag
    14281 ttagtggcgg catcaacagg agccatgaca acatccttgg atcaagcgat caagaaaaaa
    14341 gatcctattg tcgtgacagc ttggtcacca cactggatgt ttgccaagta tgacttgaag
    14401 taccttaaag atcctaaaga aacctttggc tctactgaga acatcaatac cattgctcgt
    14461 aaaggcttga aaaaagacct tccaaatgtt tacaaaatca ttgataagtt ccactggacc
    14521 caaaaagata tggaagcagt catgcttgac atcaataaag gtatgagtcc agaagctgcc
    14581 gccaaaaaat gggtagaggc aaacaaatct aaagtatcaa gttggacaaa ataagtgctt
    14641 ttgtctaaat agcaaataga gaagtctagg aattttccta ggctttttag gttaaccatt
    14701 tacttatcag caaaaccaat ggcttaaagg agaaaagccc gtccctctgt gttataataa
    14761 gcttatggaa aacaagaata aattactatt aattgatggc tcatctgttg cctttcgtgc
    14821 cttttttgcc ctttacaatc aaattgaccg ctttaaaaat catagtggtc ttcataccaa
    14881 tgccatttat ggctttcatt tgatgctaga ccacatgatg aaaagagtcc agcctactca
    14941 cgtgctggtg gcttttgatg cgggcaaaac caccttccgg acagaaatgt atgccgatta
    15001 taaggcgggt cgcgccaaga caccagagga atttcgtgag cagtttcctt atattcgtga
    15061 gatgttgaca gcccttggga ttgcttatta tgagttggaa cactacgaag cagacgatat
    15121 tatcgggacg cttgataaaa tggcggagcg cacagaagtg ccttttgatg tgaccattgt
    15181 cagtggtgat aaagatttga tccagttaac tgacgaaaat accgtggttg aaatttctaa
    15241 aaaaggggtt gccgaatttg aagaattcac accggcttac ctcatggaaa aaatgggctt
    15301 gacgccaaac cagtttattg acctcaaagc cttgatggga gataaatcgg ataacattcc
    15361 tggagtgaca aaaattggag aaaaaacagg ccttaagctc cttcatgaat ttggtagttt
    15421 ggaaggcatt tacgagcata ttgatggatt caaggcctca aaaatgaaag aaaacttgat
    15481 taatgaccgt gaccaagctt tcctatctaa aacgctcgcc actatcaata cagcatctcc
    15541 tatcacaatt ggcttagatg atatcgtcta caatggtcca gatgttgcta gcctctctca
    15601 attttacgat gagatggatt ttgtgcaact caagaaaggt cttgctagcc agatgcctca
    15661 agagccagta gctgccattt cctatcaaga agtgaccaat gtgtctgctg atttgtttag
    15721 cgcagaagac atcttctact ttgaaacgct tcgggacaat taccatcgtg aggccatcat
    15781 tggttttgct tggggacatg gtgagcagat ttacgcatcc actgacctta gcctattagc
    15841 gacggatagt tttaagcagg tcttccaaaa acccattgcc acttatgatt ttaaacgtag
    15901 caaggttttg ttgagccact taggaattga gttggtagca cctagctatg atgctagatt
    15961 agctaattac cttctgtcaa ctgtagaaga caatgagctt agcaccattg cccgcatttt
    16021 tactgacatc tctttggaag aagacgatac agtctatggt aaaggtgcta aacgggctgt
    16081 tcctgataaa gacgtcttac tagaacactt agctcgtaag gtcaaagtat tattagatag
    16141 caagtctcaa atgctagaca agctcactgc ccatgagcaa ctagacctct atcagaatat
    16201 tgaattgcct ttggctaatg tccttgctaa aatggaaatt gaagggatca aggttaatag
    16261 ggcgactttg caagatatgg cagagcaaaa caaggtcatt attgaagcgc tcacccaaga
    16321 gatttatgat atggctggcc aagaatttaa tatcaattcg cctaaacagt taggcagtat
    16381 cttgtttgag aagatgcaac tacctcttga gatgactaag aagaccaaaa caggttattc
    16441 tacagctgtt gatgttttgg aacgtttggc accgattgct ccaattgtgg ctaaaatttt
    16501 ggcttaccgc cagattacta aattgcaatc cacttatgtg attggtttac aggattatat
    16561 tctggctgat ggcaagattc atacccgcta tgtgcaggat ctcacccaga cagggcgttt
    16621 gtctagtgtg gaccctaatc ttcaaaacat tcccattcgt ttggaacagg ggcgtttgat
    16681 tcgtaaggcc tttaccccat ctcatgaaga tgccgtcttg ttgagttcag attactcaca
    16741 gattgaattg cgggtactgg cacatatttc aggggatgag catttgattg ctgcctttaa
    16801 tgaaggggca gacattcata cctcaacggc tatgcgtgtg tttgggattg acaaggcagc
    16861 agatgttact gccaatgacc gccgtaatgc caaggctgtt aactttggaa ttgtgtatgg
    16921 gatttctgat tttggtttgt caaataacct tggtatcacc cgtaaacagg ccaagactta
    16981 cattgatacc tattttgaac gctatcctag gattaaagcc tatatggaaa atgtggtgcg
    17041 tgaggctaaa gacaagggct atgtagagac cctctttaag cgtcgtcgtg aattaccgga
    17101 tatcaactct cgtaatttca acgttcgctc ttttgcggag cgtacagcca tcaactcgcc
    17161 cattcaagga agcgcagctg atattctcaa aatcgctatg attaatctgg acaaggcctt
    17221 gcaagcaggt ggttttagag ctaaaatgct gcttcaagtg catgatgaaa tcgttttgga
    17281 agtgccaaat gatgagttga ctgctataaa aaaacttgtc aaagacacca tggaagctgc
    17341 tgttgattta gctgttcctt tatgtgtcga tgaaagtact gggcagagct ggtacgaagc
    17401 caaataagtt ttcttacttg ttatttctca ttttgacaac ttatgttata ataaactaaa
    17461 aaattgtagg agaagtcatg aagctgcttt gagctttttg acggataagg ttaaaagtga
    17521 ttgaagccat gctttaggag ttatcctgct atattgaaca gctttagaat agatagggga
    17581 acaagtgatt tattcgtttc aaaatccctc agaggatgtc ctaaaagctt acttggagtc
    17641 agccaaaacc attgcggttg ttggtctttc tgaccgcaaa gacacagcag cttatggtgt
    17701 cgccaaattt atgcaggcta tggattatcg gatcattcca gtcaatccca aattagcagg
    17761 tcagcttatt ttgggagaga aggtctatgc cagtatcaag gcaattccct ttgaggttga
    17821 cattgtagat gtctttcgca gaagtgagtt tttaccagaa gttgccagag actttttagc
    17881 aggtcaggcc aaagtctttt gggcgcaatt aggccttgaa aaccaagaag cacaaaccat
    17941 tttacggtcg gcaggcaaag aggcgattgt gatgaaccgc tgcctaaaaa tagactattt
    18001 gcaattagtc gctaaaccag aatgcattac gaatcattga aactagagac gtgcgtgata
    18061 ataaaggaaa aaaggatagg agtagcagct tatggacatt cattcacatc agcaagccct
    18121 agatgcctat gaaaatgtcc tagagcatct acgggaaaaa catattcgaa ttacagagac
    18181 acgtaaagcc attatttctt acatgattca gtccacagaa caccctagtg ccgataagat
    18241 ttaccgtgac ttacagccta actttcctaa catgagcctt gccacagtct ataataattt
    18301 gaaagtttta gttgatgaag gttttgtctc agagttgaaa atcagcaatg atctaaccac
    18361 ctactatgac tttatgggcc atcaacacgt caatgtggtt tgtgaaatat gtgggaagat
    18421 tgctgacttt atggatgttg atgttatgga tattgccaaa gaagcccatg agcaaacagg
    18481 ttataaggtc acgcgtatcc cagttattgc ttacgggatt tgtccggatt gccaagcaaa
    18541 agaccaacct gatttttaga gttaaccctt aaataaaggc attataaata tagtgccttt
    18601 acaaatcaaa aacccccagt tcattttggc tgagggctat ttttatggat ggaggattta
    18661 tttagtcttt ttgatcgtca tacatcatag gagtaggctt tttattaagc tgatgaaggc
    18721 ttaaatgttc tccttcaatt gggtcatctt tgtctttgaa acgtttcttg agttgatcat
    18781 aaaaaatgac attggctgtt gtaaaatatg gtaaaagata gatattaagt aacccaaaag
    18841 taacaatatt cagtagaaac caaccggtga agctaagttg taagaaaaaa agcttccatt
    18901 tataaccttt catcatagct acacttgttt caatgacggc tatagctcct agataagtcc
    18961 cctctttaac cttatcgtag agaaggtatt ctgatagact ataagcgtaa taacggttga
    19021 tataaatacc aaaaccaatt aaggacaaaa ctgctccaaa tagtaaaaag atcagtgaaa
    19081 tgactgttga gccacctgat ttagcattga ccaaaaacgc tgaaagtccg gaaaggaaaa
    19141 taaagaggcc aaaaaaccaa attagtgacc agatgagaaa gaatagccac ttagtgatcg
    19201 ctaaaaccag caggttccca aagaattctt ttgagaaggc tgttgttgat tcggcaaaag
    19261 aaactttctg acgaaaatgc ctaacaacat caatcattgt aaaggatgct gataaaatga
    19321 aaaggctaag gataagtcct agtagtaatg ggaaataact agccgctagc gagacttcaa
    19381 taccactaga taggacgtaa ccttgatgaa tctcaatacc gaaatgaaac ataaagagaa
    19441 gggttggaat taaaaatagt aaatacttgc cagagagatt ttttaacgtg tctctagcct
    19501 ggcctttgat tgctttaatt gacataacag actcctttat ttcattatac cataaaacaa
    19561 aatgagacag ctaaccatta ttttgactat acttttttgg gaaagcatga caaattatgg
    19621 attttttgat aaaatgatag gcgctagaac aacatgtcat cttgaagccc ttcattatga
    19681 tggaaactca ggcagatcaa aaaagctcaa gactgtttat cttgatagca aggaagaaag
    19741 cacatgacag attatccgat taagtatcgc cttatcaaaa cagaaaagca caccggtgca
    19801 cgcttgggcg aaattatcac ccctcacggg acctttccga caccaatgtt tatgccagtg
    19861 ggaactcagg ctactgttaa aacacagtct ccagaagagt taaaagcaat tggatcaggg
    19921 attattttat caaacactta tcacctctgg ttgcgtccag gagatgagtt gattgctcgc
    19981 tctggtggtc tgcacaagtt tatgaactgg gatcagccaa tcttaaccga ttcgggtggt
    20041 tttcaagttt actctttagc cgattcacga aacatcactg aagaaggagt gactttcaaa
    20101 aatcacttga atggctcaaa aatgtttcta tcacccgaaa aagccatttc cattcagaat
    20161 aaccttggct cagacatcat gatgagtttt gacgagtgcc cgcaatttta ccaaccttat
    20221 gattacgtga aaaaatccat tgaacgtact agccgttggg cagaacgtgg cttaaaagcc
    20281 catcgtcgtc ctcatgacca aggattattt ggaattgtac aaggagctgg atttgaggac
    20341 cttcgtcgtc agtctgcggc agatttggtg gctatggatt tcctaggtta ttctattggt
    20401 ggtttagctg ttggggagag ccatgaagaa atgaatgccg tccttgactt tacgactccc
    20461 ctcttaccag aaaataaacc tcgttacctg atgggagtgg gagcaccaga tagcttgatt
    20521 gatggtgtga ttcgtggtgt cgatatgttt gactgtgtct tgccaacgcg tatcgcccgt
    20581 aacggaactt gcatgactag tgaggggcgt cttgtgatta aaaatgccaa attcgctgaa
    20641 gattttaccc cacttgatca tgactgtgac tgctacactt gtcaaaacta tagccgtgcc
    20701 tacattcgtc acttgctaaa agcggacgaa acttttggta ttcgtttgac aagctaccac
    20761 aacctttatt tcttggttaa cttgatgaaa aaagtacgtc aggctattat ggacgataac
    20821 ttacttgaat tccgccaaga ttttcttgaa cggtatggtt ataataaatc aaaccgtaat
    20881 ttctaattaa aaatgctatg atcctggaac tgagggcgat ctatcgtctt tggtttcagc
    20941 tttttttgta tagacggatg tcctattgct ttcaactgat aggtcactct ttaaagggaa
    21001 gttcttgttt tacgtgttct ttttcagaaa aaagttaccc ttttgtaaaa atagagttga
    21061 caaatcataa gcttttgatt aaactgttac aagaggatga gatatgacgg actgttttgg
    21121 aattgacctt gaccaagagt atcggtgcct acattatcat accccgcttg atattgttgg
    21181 gctcaaatgt gctttttgtc agacttatta tgcttgctac cattgtcatg accagttagc
    21241 agatcatgcc tttgtgccaa caggacatca agaaacatct cctgttattt gtgggcattg
    21301 tcgaaagctc ttgagcctag ctgagtatgg ttgtggatgc tgtccttatt gtcaaagtcc
    21361 ctttaatcca gcctgtcata ggcacaagga tatctatttt ttaaaggagt cgtaacagat
    21421 gtttacaacc aaggaacttg ttaaggtggc tatgatgacc actttgatta ttattttagg
    21481 ctttattcct gctatcccgc taggctttat cccagttcct attgttttac aaaacttagg
    21541 tgtcatgttg gctggattga tgctgggtgg taaaaaggga accttatctg ttttcttatt
    21601 tttagtgatt ggccttttct tacctgtttt ctcaggctca agaacaacca ttccagtatt
    21661 gatggggcca tctgctggct atgttattgc ctaccttctt gtgcctattg tcttttcatt
    21721 actttaccgc aactggttct caaaaagcac gccacttgct ttcttagcct tattcatttc
    21781 tggtgtcttg ctagtggatg tgatgggagc gatttggttg gcagcttaca cagggatgcc
    21841 gttgatgact tctctgttat caaacttggt ctttattcca ggggatacca tcaaagcaat
    21901 tattgcaacg attattgctg ttaaatacaa agacagtttc ttgaatacaa aacagtaatc
    21961 taatcatcaa atagttaagt tgtgttgaac aggtcttggc agatttatct gctaggacct
    22021 gtttttggtg ggtctcaatc ctctttgaca ctaatttttg ttataataag agttaaagca
    22081 agaaagaagg gtttgagatg aaattaacca ccttagggtc ttggggagcc tatccctatc
    22141 aagatgcagg cacaacctct tatttggtca caggacatga cggctttcag ttattgatgg
    22201 atgctggtag tcgagcgctc aatgagctgg aaaaagaaat cagtcctctc gatttggatg
    22261 cagtgattat tagccattac catccagacc acgtggccga tttaggcgtg ttgcgccatt
    22321 attttcaact ttatcctaaa cacctgtggc agcctaaagt attgcccatt tatgggcatg
    22381 atgaggaccg acacgaattt gctaagttaa gcattcctga tgtttcagaa ggtagagcct
    22441 atgatgtcac tggagttgaa cagattggtc cttttgacat tacctttctt aaaacagttc
    22501 atccagttgt gtgttatgcc tttcgaattg tagaaagagc gactggtcag gtacttgtct
    22561 ttactggaga cagtggttat tttgaaggat tggcagactt cgcaaaagaa gcagaccttt
    22621 tcttagcaga tgtttactta tacgaaggca atgaaaatca tatggcccat ttgaccagta
    22681 aggaagcagg actaatggct agccaggcag gtgttaagaa gcttgtcttg acccacatgc
    22741 caccggttcc tccagaaggt attgatcctg acaatcactt ggaagtgttg aggcaagaaa
    22801 cacaagccta tgcaggtaat attcctgttg accttgcctt accacacaaa tcttggaact
    22861 tggggagtct ttcttgatgc catatagttt agaagagcaa acttatttca tgcaagaggc
    22921 tttaaaagaa gccgaaaaat ccttacagaa agctgaaatc cccattggct gtgtcattgt
    22981 caaggatggt gagattattg gtcgtgggca caatgcgcgt gaagagagta accaagccat
    23041 tatgcacgct gaaatgatgg ctattaacga ggctaacgct catgaaggca actggcgttt
    23101 attagatacc acactctttg tgaccatcga gccttgtgtg atgtgtagtg gtgccattgg
    23161 gctagcaagg attccgcatg ttatttatgg agccagcaat caaaaatttg gtggagcaga
    23221 cagcctttac cagattttga cagatgagcg cttaaaccat cgcgtgcaag ttgaacgagg
    23281 cctgctagca gcagactgtg ctaacatcat gcaaaccttt ttccgccaag ggcgagagcg
    23341 caaaaaaata gctaagcatt tgatcaagga acagtcagat ccctttgact agagttttaa
    23401 ggagtttgtt atcacatgca tttttggtga agggtagcct gtcaaaatac tgagtgaaac
    23461 gttagaccat ttttccaatg gttgttagat tcaacatacg aagatagaat atacaaaagg
    23521 gcgtttccaa gtactagaag cgctcttttt cagacccaat cgagatgaaa acaatcgaaa
    23581 aataaaacac gtgatgacta gatgagttgg tcattcttaa aaagatttac tatctaaaaa
    23641 cagatagtaa tggctcacct tatttttgtt tttagtaaac ttatcaagtt cagacttcta
    23701 gggctcagag ctgtcagtta tctgtggcgt agattgatac tgacacaggg attaaaaaca
    23761 agtgacttat aggcatggct tgagttattt aatcttttgt cttagctgat atattttgct
    23821 aaagcattaa aaaagagctc atcactgttg ctaatgttac aagcattaga tgtgctcaat
    23881 ctgaaaaggt tatatctatt gaagacggtt agaataataa tcgccttcaa ttgtgttagt
    23941 atatcaattt cttgtaatgt ttgacaaaga taatcatctt aactttgtgt ttcatgtgtc
    24001 taaacctagt tcctactagc aaatgaaata ctaagagtct ctggtaagag tccataggta
    24061 aagcccgtat aattattcca atactgattg aaaaggttat gataacctgt ttgattcgtc
    24121 gttaaatcag ttaccatttg ttgataatca tcttgatgag caaattgtag agacagtggc
    24181 tcttgtctat ttaacaactg attttcaagg ctttcaagga tggcgtcact gtcaaacgtt
    24241 gagatatagc tttgatgacg tttagaataa agcaaagaat catctgtaca agaaggtata
    24301 gtccaaacat tttcaaaacg ttctttagta ttaaaagcaa tgtctttgct tggctgatgt
    24361 gataaggcca ttagatggtc tggcaggcat agaaaactgt aattgatagt tccttgcttt
    24421 tgatgtgaga gatggttatc aaaaacaggg tcaccccaag tgacatcaac gccataataa
    24481 gtgttattaa tttgaacagc attccatgca tgtgcaaaag attgctgagg ttgctgagat
    24541 gtaccagttc cacggatata ggcgactgga atgccagctt tttgacaaag aaactgaaag
    24601 gcttgggcat agccattaca aacagataaa tgatcaataa aaacactttt aatgtcttga
    24661 ttagaagcga cctgggcttg actgcctgat tgataggctt caaaggcttt tttattgtag
    24721 tctgtgtctc gaatgatgac ctcataaaaa tatttgacct gctcatagcg atcctttgat
    24781 ggcatgtttg cgacgatatc attaccgatt gcttgcaagt cttgataaac gttcttggca
    24841 tcttctggga taggaaaggt gacaaagacc gtttgatcag aaaactcaaa tcgataatcg
    24901 gcagatgtaa tccagtaaaa ttcgggatta tccatcacaa aggcgtcaat cgttttaatt
    24961 aagctttttt tagaagccgg cgtcaaactg atgatttcac gaaactgtgc tagactatcg
    25021 tataaagtga ggtaattttc ttgttcggtt ttggataatt gttggaaata ataccgttgt
    25081 cttacttgtt tgacgatttg ttggcgcttt tttccggtta aagaaaaaac agaatcggta
    25141 ttagaaggtt tgctagtgtt gtgacacgca gacataccaa ctgtcataag gccaattact
    25201 gttaagattt taatcttttg tttcatcata actcccattc taatctaata atcttattat
    25261 aacatagaga atagctggaa tggggagagg gaaagatttt caaaaagcaa aatcgtgttt
    25321 ggaaagggtc atgatttttc taggtattca gtccatcttg tcccaaaatg aagctatgct
    25381 cacttgaaag tgattttact tatttggaaa acttgcaaac tgtccgtaat atgatataat
    25441 aataggcgga gcaacacttg tgcgtgaagt gggtcagggg aggaatccag cagccctaag
    25501 cgattttcgg gtgtgtgctc tttttttgtt gactttacta aagtaatctc ttccttctat
    25561 agtgtcatca gttgttgaaa ccgattgata tttttattta ggttaagagg tataaaacag
    25621 gacataaaaa gttttaaatg aaaacaaata ttttgacaat tatcatatta tcatgtgttt
    25681 ttagctatgg aagttaatta gcttatgcag atgaaaattt aaaagattta aaaagaagtt
    25741 taaggtttgc ctataatatt accccatgcg attatgaaaa tgtagaaatt gcatttgtta
    25801 ctacaaatag catacatatt aatactaaac aaaaaagatc ggaatgtatt ctttatgttg
    25861 attctattgt atctttaggc attactgatc agtttataaa aggggataag gtcgatgttt
    25921 ttggtctccc ttataatttt tccccacctt atgtagataa tatttatggt ggtattgtaa
    25981 aacattcgaa tcaaggaaat aaatcattac agtttgtagg aattttaaat caagatggga
    26041 aagaaactta tttgccctct gaggttgttc gcataaaaaa gaaacagttt actttacagg
    26101 aatttgattt taaaataaga aaatttctaa tggaaaaata caatatctat gattcggaat
    26161 cgcgttatac atcggggagc cttttccttg ctactaaaga tagtaaacat tatgaagttg
    26221 atttatttaa taaggatgat aagcttttaa gtcgagacag tttctttaaa aggtataaag
    26281 ataataagat ttttaatagt gaagaaatta gtcattttga tatctactta aaaacgcact
    26341 agtgctattc tccccccttt gctttttaag tattcaaatg attgccattt ttagataatg
    26401 agagtaagta atgttaagaa gatagcatga gaaagtattt acaggtgatt ggggcttcaa
    26461 ttgcctttgc gggtgtggcc ttatgcattg atcatatgca tgatggggtt attacccgta
    26521 ttgaaatgat aaaatcctta aaataagtta ttaaggtaaa gcggcctcag agcctttttt
    26581 catcatattt ttaggaaata tgaaatccta ttttttctta aaaaaccact atgatgagaa
    26641 tatgcttgca ttgacacatt ttttatgtct gaaaaaacga aaaccttttc aaaaaaccta
    26701 gctttttcac aggtgaaaac cactaaaaac cattgaaata ttagatagaa aaggttatca
    26761 tactaatgaa acttaaaatt ttaagggagc gaaactcatg tcacatatta catttgatta
    26821 ttcaaaagtc ctcgagtcat ttgcgggaca acatgaaatt gattttttac aaggtcaagt
    26881 aacagaagct gacaagttat tgcgtgaagg aactggacca ggttcagatt tcttgggctg
    26941 gcttgatctt ccagaaaact atgacaaaga ggaatttgca cgtatcttga ctgctgctga
    27001 aaagattaag gcagacagcg aagttcttgt ggtgatcggt atcggtgggt cataccttgg
    27061 cgccaaagca gcgattgatt ttttaaatca tcattttgct aacttgcaaa ctgccaaaga
    27121 gcgcaaagcc ccacaaattc tttacgctgg aaactctatt tcatctactt accttgccga
    27181 tttagttgag tacgttcaag acaaagagtt ctcagtcaac gtgatctcta aatcaggtac
    27241 aaccactgaa ccagctattg cctttcgcgt gttcaaagaa cttttggtta aaaaatatgg
    27301 ccaagaagaa gctaacaaac gtatctacgc taccacagac aaagttaagg gtgctgttaa
    27361 ggtagaagct gacgctaaca actgggaaac atttgtggtg ccagataatg ttggtggtcg
    27421 tttctcagtc ttgactgctg ttggtttgtt gccaattgct gcatcaggtg cagatattac
    27481 tgctcttatg gaaggggcaa atgctgctcg taaagacctt tcttcagaca aaatctctga
    27541 aaacattgct taccaatacg ctgctgttcg taatgtgctt taccgtaaag gctacatcac
    27601 tgaaatcttg gctaactacg agccatctct tcagtactta ggcgaatggt ggaaacaatt
    27661 agctggtgaa tcagaaggaa aagaccaaaa agggatttac ccaacttcag ctaacttctc
    27721 aacagacctt cactcacttg gtcaatttat ccaagaaggt taccgtaatc tctttgaaac
    27781 agttattcgt gttgataatc ctcgtaaaaa tgttatcatt cctgaattag cagaagacct
    27841 agatggactt ggttaccttc aaggtaaaga cgttgatttc gttaacaaga aagctacaga
    27901 tggtgtgctt cttgcccaca cagatggcgg cgtgccaaac atgtttgtca ctcttccagc
    27961 tcaagacgag tttacccttg gttacactat ttacttcttt gagcttgcca tcgctgtttc
    28021 aggctacatg aatgctgtta acccatttga tcaaccaggt gttgaagctt acaaacgtaa
    28081 catgtttgcg cttcttggaa aaccaggttt tgaagcatta tcagcagagc ttaatgctcg
    28141 tctctaatca acagatagtc aaaaagactt cttccttgta caagagctta aaagttagcc
    28201 aagcaatcta agaattgggg cggcacttcc atcatcgagt ggatacaagg ttaagtaaaa
    28261 gcgataataa agtgcgcttc cagaacatgg gagcgcactt tattatgcca aatttcagat
    28321 aagaccttca aaaaagggaa gaagatccta caagaggagt tgaaccgcta aaacagttcc
    28381 agttctgttt ctaggcaaat agcaatggtt aaaaagagag cttatcaagg ttgcaagtga
    28441 caaccttaaa gaccctctag actgtgaaag tatctaggag ggactgtcaa aaaattaaga
    28501 aggaactctc caaagttctt ctaaacgttt ttggtagtgg ttctggtgca aggctaagat
    28561 ggttttgatt aaatcttcgc gctgctgttg gatacagtcc aaactcaaac caaacaagcg
    28621 ggtctctttg ggaaaaacac cgagttcttt taagaaaggc aagagtttct ggctggtcac
    28681 aaccagatct acaggtttat catagggata aatattatca gataagatat tgacccgtga
    28741 cagttcaact ttgtaagaag ggatagttga ggtgatgaaa ttagctataa cgttaccaac
    28801 agtttcttgg ctctcaataa cagtaatatt gattggagca atagagcttt ccaagatctg
    28861 ctcaaggtat aaacacatca agtgtaagtg accagaacta atactgcctt gacggcctgt
    28921 gtcataaagc caatctttga taacggtttc aagcttatct agtagtagca tgttaccttg
    28981 atattgatca aaataataac catcaaaggt aattaaagtt tgtaaattgt agagagttct
    29041 tttgaaaaaa ggaattaagt tagggatatg ctcatgaata tctgaatact ttccaactag
    29101 tgcctgaaga cgatggatta gtaaatgata atcaggatct ttggtgatta aatggtaaag
    29161 ttgttgtcgc tgatgacttg tccagtaccc actcaagaag gagttatcag tcgttaaata
    29221 aattaaaaag agatagtcaa aatcatcaga cgaaaatgtg acacgagttc gaggtgctag
    29281 ctcatccacg gcaatggttt tgatattgtc aaaaataggc aaggatttga gatgttcaaa
    29341 aagagctaaa tgaggcaaat gaacaggata gcgatggcgc ttccaagtca acatcaacag
    29401 cacatcaaaa aacaagaagc gtctatctaa aaaggcagaa ggttgtaagt ttttttgtgc
    29461 tgcaaagata aaagcatgaa tcgtttcaat gtctgcaggt tgtatatcat ataatataat
    29521 gccgtactct ttatgtaaaa gagcaatcaa ataccgtatt ttaagttcat ctccgataac
    29581 agtattgtct acaatattta aaccaatgtc ttgtaaataa tgttttaatt tatgaataag
    29641 acgataagct tttgactggg atatcccttg ttttcgtgta taaacagcga ttgatttgtg
    29701 tttgggatta tctagtaata agaatgtcaa catttttaga gtatctgata aggcaaaaat
    29761 gtcataaaaa aatgcttctc gcttatcatt taatacctca caataaatac gagatttaat
    29821 aagctcaata cgtaagtacc ctttaaataa ggcgttaaat tgtcgaagat actgctttat
    29881 ttttaaagca gtcaaagttg tttgagaaca agctgctgcc atcgtcagtt ctttttctgt
    29941 caacaaaata gccagtagga ttttctggtc aataatatcg gattccaaat aataatctaa
    30001 caatgtaatt tttctctcct taaattaaat tgtataatcc tatatattgt agcgaatcta
    30061 ccgtaaaagt caactaaaat caataggatt accagtatag tcacaataaa gatcatcaaa
    30121 aagcagcaaa cttcatcaat agattgattg atgcgtgttt ttagcccata attgagagag
    30181 ctaagaacac acgggtgata tcatattttt gctgttgact ttttaaattt aaaaacctaa
    30241 ccagccggtt aactggtcag gtttaaacaa gggagggcac ctaagaagat aggtgcccag
    30301 gagatttatg aaaagggaaa acaaggggaa aacctattct cccaacggtt taggtaaacc
    30361 gctttttagg atgttttcat tctacgatag taaccttaaa gttttcttaa atgattcttt
    30421 agaatgcctt tatttttaat cttttttgag agagctagtt tcttgtcagc cttgaacctt
    30481 tttcctaatt tatggtatga taagaagatg atgaaaaaag agattctcaa agaactcttc
    30541 tagtctttac gaactatgga tgtagactta aaacgtcaaa atgatcaagc tttattagtg
    30601 gatgttgtta gcaatcaagc ttatcagcgg gccaatacga ttgccaaatc aaacgattta
    30661 tgatattgct gtttaggagg tttatcttag atgacacggt tattaaaacg atatcctatt
    30721 actattttcc ttttagggtt aacaggctta atttttatag caatgcaagt ggtatatgga
    30781 catttagcaa ctggtgctca agctatttat caagttggag gtatgtttgg attactagta
    30841 aaagcaatgc cagaccagtt gtggcgattg gtgactccga tatttattca tattggcttt
    30901 ggtcattttt ttgtcaatgg attaacacta tattttgttg gtcaaatcgt cgaagacctc
    30961 tggggctcac gccgtttttt attactttat gttttatcgg gtgttatggg caatgccttt
    31021 actttttggt tgactcctga aacagtagct gcaggagcat cgacgtcgtt atttggactt
    31081 tttgctgcta ttgtagtatt gagttttttg ggtaagaacc aagcgttgaa agatttgggc
    31141 aagtcatacc agacgttaat tgtagtcaat ttactgatga atctttttat gccaaacgtg
    31201 agtatggcag gccatattgg cggtgtcgtg ggtggtgcgt tactgagtat agtttttcca
    31261 actaagatga gagtgataac aatgaagaaa accaagcgaa tgttggcttt agtgagctat
    31321 ggtattattt tggttggtgt gttagtgctt gggtttttat aaaaataagt gagtggttag
    31381 cactgttact tctcagatga ctagtaggat gaaatgactc aaaaccataa aaataaggag
    31441 ggattttccc tccttatttt tatggttttg ttttctctag tgctttgccc agttggatga
    31501 tgtaggcttt caagtcatct ttgacttgag gatgtttcag ggcataatcc aaagaagttt
    31561 tcataaaccc aaatttatcg ccaacatcat agcgtttccc tttaaactca cgagcaaaga
    31621 cacgctgtgt tttattgagg gtatcaatag catcagtcag ttgaacttca ttgcctgcac
    31681 caggttcttg tttttctaaa atactaaaaa tttctggtgt gagcaagtaa cgtccaataa
    31741 ttgctaaatc actaggtgca tcttgaggtt gtggtttttc aacaaaagta tccacactat
    31801 agagtccttt tactgctttt gcttgaggag caatgatacc gtagttagag acatcctcgt
    31861 gaggaaccct catgacggca atggttgcgg catgagtttc ttcatagtca tcgatcaatt
    31921 gtttagttaa tggttttaca tttggatttg taatatccat cagatcatca cctagcatga
    31981 caacaaaagg ttcattgcca acaaaggtct ttgcttgaag aactgcgtct cctaatcctc
    32041 ttggatgact ctgtcgaata aagtgaagat taatagaagt ggtctcgtct actaacttta
    32101 gaagttcgat ttttccttta gcctgtaaat tatattctaa ttcaaaatta gaatcaaaat
    32161 gatcttctat ggaacgtttg gattttccag taacgataag aatttcttcg atacctgatt
    32221 ttagagcttc ttcaacgata aattgaatag ttggtttatc aacaataggt agcatctcct
    32281 tggcaagggc cttggttgca ggtaaaaaac gtgtgcctaa acctgctgcg ggaataatag
    32341 cttttctgac tttggtcatc agcacctcct tttattttag tgacgcatgg cttaatgcca
    32401 ttcattttca gaacgaaatt catttgacat catgccgagg atgctttctt tgatatcagc
    32461 gccctcgtag atggacttat aaatagctgt tgtaattggc atgtaaactc cgaggtcttg
    32521 ggcaatttca taggctacct tagttgttgc gatgccttcg ataaccatac ccatgttgcg
    32581 ttcaatatct tctaattttt caccacgtcc aagggcagct ccagcccgcc agttacgtga
    32641 atggacagaa gtacctgtta caattagatc accaacacca gataacccac tgtaggttaa
    32701 cgggtcagca ccaagcttga cgcctagacg ggtgatttca gctaacccac gagtaattac
    32761 cgctgctttg gcattatctc catacccaag tccatggaga gctcctgctc caacagcaat
    32821 aatgtttttg agggcaccag ctgtttcaac tccgatgacg tcggtattgg tataaagtcg
    32881 gaagtagtgg ttactaaaga gggactgaac atactttgca gcttcaatat cttttgaggc
    32941 tgccgtgatg agagtaatat cgcgaacgat agtttcttca gcatgactag gacctgatac
    33001 aacgaccact tcactacgaa aatgagctgg aattacttct tctaggatag ttgataaacg
    33061 ttcgtgggtc tctggttcta gaccttttga ggcatgcatg accactactt tatgatctaa
    33121 aatggcggca acttgtctag caactaatcg tgttacttta gttggcacaa caaaaagcac
    33181 cgcatcaaca tctgataggg cttgacctaa atcaagagtt gccgtaatgt ttttgtctaa
    33241 cacaatgtct ttgaagtagt gtctattggt atgcttggta tttatctctt caatttgatc
    33301 aggaatattt ccccataaac ggacgtcatg gccattgtca ttaagaacct gagaaagggc
    33361 agttccccaa gaaccaggtc ctaaaatagc tactttttgt tttgtcattc taaattctcc
    33421 ttcaagagct agtcactcta ttataacata acaccttgat tagctctatt agaaaaggta
    33481 tatggtcttg gctaataaga cgttcccaag agagctagct atattaataa tgttgtttaa
    33541 taagctttat caggtgagct gttgtcatgg ctttgccctg ttctttttag ttatttaagt
    33601 tcggaaactt atttttaaaa ataaagatat tttaattgac aatagttatc tagagaacta
    33661 aaatacttat catagaaact attaaggaaa agaaggaggg aagagatgtc acaagtgata
    33721 ggtgatttac gtgaattgat acatcaaatc gaacaaatta gtgatgagat tgcaaaaaaa
    33781 tatgatgtag agcatctagc aggtcctcaa ggttatgttc ttgttttttt agctaaacac
    33841 caaaatcaag aaatatttgt caaagatatt gaaaaacaac ttcgtatctc aaagtcagtt
    33901 gctagtcatt tagtgaaacg tatggtcaaa aatgggttta tcaatgtgat gccttcccaa
    33961 gtggataagc gttataagca agtagtgtta gcgcaggttg gtagagataa attgcctttg
    34021 ttgcgggagt gtcgtaagga tatcgagcac tattttttaa aagaaattac aaaagaagag
    34081 ttgctgacag cgaaaaaagt aattgaacag ctcaagcaaa atatgctaac ttataaagga
    34141 gacaacgatg cttaaagacg caatcttacg ttataaatgg tatgctttag gctcattttt
    34201 tatggttatt ggggttgttg caagtagtct cttgcaacca cattatctta aatctgtgct
    34261 aagcgctgtt attcaaaata atcaagagaa aatttatgag gttgggaaac cattacttat
    34321 tattgccctt ttagggttaa tgtctggagc gattaatacg gttttagctg ctaaaatagc
    34381 tcaaggtgta tctgctgata tgagggagaa gacctttcga aaaatccaag acttttcata
    34441 tgccaatatt gaagctttta atgctggtaa tcttgtggtt aggctaacta atgatatcaa
    34501 tcaaatccaa agtttagtca tgatgatgtt tcaaattctc tttcgtttgc cgatcctttt
    34561 tattggcgcg tttattatgg cagttcagac attccctcaa ttatggtggg tcattgttgt
    34621 aatggttatc ttaattgccc tcatcatggg tttggtgatg cgtcaaatgg gtcctcgttt
    34681 tggtaaattt caacggttaa tggataagat taatcacatc gctaaggaaa atctccgtgg
    34741 cgttcgcgtg gttaaatcat ttgtacaaga acaacaacaa tacactaaat ttaaagaaac
    34801 gtccaatgat cttttggcgt taaatttatc tattggttat ggtttttcac taatgcagcc
    34861 ggctttaatg ttggtgtctt atttggcagt ttatgtttct ataaatgttg tttcgaccat
    34921 ggtcgaaaca gatccaacag tgattgggaa tattgcctct ttcatgactt atatgatgca
    34981 aattatgttt tcaattatta tggttggttc catggggatg caagttagtc gtgcttttgt
    35041 ttctatggct agaattaggc aaatattgtc tacagaacct gccatgacat ttgaaaatga
    35101 aaaggaagaa accatctcag gaagcattgt atttgacgat gttagtttta catatcctaa
    35161 tgatgatgag ccaaccttga agcacatttc ttttgctatt gaacctgggc aaatggtcgg
    35221 catcgttggt gcaacaggat ctgggaaatc aacgcttgca cagctcatcc ctcgcttatt
    35281 tgatcctcaa gatggccaaa ttttgttagg aggaaagccg attaaaaccc taagtcaaac
    35341 aaccctgcgc caatcggttt ccatcgtgtt gcaaaaggct attctctttt caggaacgat
    35401 agctgataac cttcgccaag gctcagcaaa agctgatatt gatgctatgc aaaaagccgc
    35461 tcaaatcgcg caagcaaaag aatttattga tcgcatgaat agccgttatg agagccaagt
    35521 tgaagagcga ggtagtaact tgtctggcgg acaaaagcaa cgtctgtcta ttgcacgtgg
    35581 tgtcattaat catcccaaaa tccttatatt agacgattcc acttcagctc ttgatgcaaa
    35641 atctgaaaaa cgcgttcaag aagccttaag tcataaatta gaaggtacaa ctacagttat
    35701 tgttgctcaa aaaatttcat cggtagttaa ggcagataag atcttagtcc ttgaccaagg
    35761 acagttaatt ggagaaggaa cacacgcaga gttggtggct aataatgcga tttatcgtga
    35821 aatttatgag acacaaaaag gaagggagga gtagtgatga aaacagcacg ttttttctgg
    35881 ttttatttta aacgctatcg tttctcgttt actgtcattg ctgttgccgt tatcttagca
    35941 acttatttac aagtaaaagc tcctgtcttc ttaggggagt ccttgactga gttgggaaaa
    36001 atcggtcagg cttattacgt tgctaagatg agtggtcaga cacattttag ccctgattta
    36061 tcagctttta atgccgtgat gtttaagctt ttgatgactt atttctttac tgttttagct
    36121 aatctaatat atagtttctt actcacacgt gttgtctcac attcgaccaa ccgcatgcgc
    36181 aagggcttgt ttggtaaatt agaacgttta accgtcgcct tttttgaccg ccataaagat
    36241 ggggagattc tttctcgttt cacgagtgat ttggataata ttcaaaactc gctgaaccaa
    36301 tccttggttc aagtggtgac taatattgcc ctttacatcg gcctggtctg gatgatgttt
    36361 aggcaagata gccgtttagc tttgttaacc atcgcatcaa ccccagttgc tctcattttt
    36421 ttagtgatta acatccgttt ggcaagaaaa tacaccaata tccaacagca agaagtcagt
    36481 gctttaaatg cttttatgga tgaaaccatt tcaggacaaa aggctattat tgtacaaggt
    36541 gtccaagaag atacgatgac agccttttta aagcataatg aaagggttcg acaagccacc
    36601 ttcaaacgcc gtctgttctc aggacaatta tttccagtca tgaatggaat gagccttatt
    36661 aacacggcta tcgtgatttt tgtcggttca acaattgtcc tcagtgacaa atctatgcca
    36721 gcagcggcag cgcttggttt agtggttact tttgtacaat attcccagca atattaccaa
    36781 cccatgatgc aaatcgcgtc tagttgggga gaattgcagc tggcctttac cggtgctcac
    36841 cgtattcaag aaatgtttga tgaaaccgaa gaagttcgtc cacaaaatgc accagcgttc
    36901 accagcttaa aagaagcagt ggcgattaac cacgtcgatt ttgggtatct tcctgggcaa
    36961 aaagttttat cagatgtgtc aatcgttgca cccaagggca aaatgattgc cgtggttgga
    37021 ccgacaggtt ctggaaagac cactattatg aacttgatta accgtttcta cgatgtggat
    37081 gcaggttcga ttacctttga tggccgtgat attcgtgact acgatttgga tagtcttcgt
    37141 caaaaggtag ggattgtgtt gcaagagtca gttctttttt caggaaccat tacggataat
    37201 attcgttttg gtgatcagac cattagtcaa gacatggttg aaaccgctgc gcgtgcgacc
    37261 catattcatg actttatcat gtccttacca aaagggtaca atacctatgt ctcagatgat
    37321 gacaatgtct tttcaacagg tcaaaagcag ttgatttcta ttgctaggac gctactgact
    37381 gaccctgaag tgttgatttt ggatgaggcc acttcaaatg ttgatacggt taccgaaagt
    37441 aaaattcaac gggccatgga agctatcgtg gcaggacgaa ccagctttgt cattgctcac
    37501 cgcctcaaaa ccattttaaa tgccgatcac attattgtgt tgaaagatgg caaggtcatt
    37561 gagcaaggaa atcatcatga gctattgcat caaaaaggct tttatgccga attgtatcac
    37621 aatcaatttg tctttgaata gatggtatca gctccgcgtc ttagcggagt tttttggtga
    37681 acaataaagc agtcaagctt tctttcctga tatggtataa taacaagcaa gagaaaaaac
    37741 aattagaaag tagccacaat gattgattta caagagattc tcgctaacat gaatcccaat
    37801 caaaagataa attatgacag ggtcatgcaa cagatggcca aggtttggga gaaggaatcc
    37861 gtgcgcccca gtattttaat gcatgtctgc tgcgccccat gctccactta caccctagaa
    37921 tacctgacgc agtttgctga cattacggtt tactttgcca attctaatat tcaccctaag
    37981 gacgaatacc atcgcagagc ttatgtgaca caacagtttg tctccgagtt caacgctaaa
    38041 acaggcaata ctgttcagtt tctcgaagcg gactatgtcc ccaatgagta cgttcgacaa
    38101 gtgcgaggtt tagaagagga accagaaggt ggggaccgtt gccgtgtctg ttttgattac
    38161 cgactagaca agaccgctca aaaagcagtg gaactaggtt ttgactactt tgccagtgcc
    38221 ctaaccatca gtcctcataa aaattcgcaa accattaatg atgtgggcat cgatgtgcaa
    38281 aaggtttaca ccaccaaata cctgccaagt gatttcaaga aaaacaatgg ttatcgcaga
    38341 tctgttgaaa tgtgtgagga gtatgatatt taccgtcaat gctattgtgg ctgtgtctat
    38401 gctgccaaaa tgcaaggtat tgacttagtt caagtgaaaa aagatgccaa agcttttatg
    38461 gcagacaagg atttggataa tgatttcacc cacatccgct ttagttatcg tggagatgag
    38521 atgtgatggc atgattaaaa gtggtccgtt taaagttgac cgcttttttg ctattctttt
    38581 acgaatagtc tataataaga ggatatgatt gacttgaaag gatataccta tcataatgac
    38641 aaaaactcgt ggtttcgagc ttgtttcaag ctttactaat cctgatttac taccaaaacg
    38701 tgagacgact catgcagctg gttatgacct gtctgttgct gaggctgtga ccattgcccc
    38761 aggggagatt aagttggtac caacaggggt taaggcctat atgcaagatg gtgaggtgct
    38821 ttacctctat gatcgttcgt caaatccacg aaaaaaaggg attatcctga ttaattcagt
    38881 aggtgtgatt gatgcagatt attatggcaa tgaggctaat gaaggacata tttttgcaca
    38941 aatgcaaaac attacagatc accctgtgac attagctgtg ggtgagagga tcgttcaggg
    39001 ggtttttatg ccttttttaa ttgctgatgg tgaccaagcc agaggtgaac gaacaggtgg
    39061 ttttggttcg acagggcagt aaagcgattt aacaaaaatg cttatgacag cagacctatt
    39121 ctttaagagt gggtttgtct tgtctagggg agggagatta ctatggcaaa gaaaaaagca
    39181 acctttatct gtcaggagtg tggctaccag tcgccaaagt atttagggcg ctgtccaaat
    39241 tgctcggcct ggtcttcttt tgtggaagaa gtagaggtca aagaagtcaa aaatgcccgt
    39301 gttagtctag ctggagaaaa gtccagaccg gttaaactaa aagatgtgga taatattagt
    39361 tatcacagaa cacagactga catgtctgaa tttaatagag ttcttggagg gggtgtggtt
    39421 cctggaagct tgattttaat tggtggtgat ccgggtattg gaaaatccac cttactcttg
    39481 caggtatcca cgcagctcgc taataaggga acggttctct atgtgtctgg ggaagaatca
    39541 gcagagcaga ttaaactgcg gagtgagcgt ctgggtgata ttgacaatga attttaccta
    39601 tatgccgaaa ccaatatgca agctattcgc acagaaattg aaaatattaa accagatttt
    39661 ttaattattg actccattca gaccatcatg agccctgata ttacaggtgt tcaaggatca
    39721 gtcagtcagg tgagagaagt cactgcagaa ttgatgcagc ttgcaaagac gaacaacatt
    39781 gcaaccttta ttgtgggaca tgttaccaag gaaggaacct tagctggtcc ccgtatgtta
    39841 gaacatatgg tggataccgt tctctacttt gaaggggaaa ggcatcacac ctttcgcatt
    39901 ctgcgggctg tgaaaaaccg ctttggctct accaacgaga ttggcatctt tgaaatgcag
    39961 tctggcggct tggtagaggt cttaaatcct agtcaagtct ttttagagga acgcttagat
    40021 ggggcaacag gatcggctgt cgttgtaacg atggaaggaa gtcgtcctat tttagcagag
    40081 gtgcaatctt tagtgacacc aaccgttttt ggcaatgcca gacgaaccac tacgggactt
    40141 gatttcaatc gcgtaagcct aataatggca gttttagaaa agcgctgtgg tttactctta
    40201 caaaatcaag atgcctacct caagtcggct ggtggtgtca aactagacga acctgccatt
    40261 gatttggcag tcgctgtggc tatcgcatcc agttataagg agaaaccaac cagccctcaa
    40321 gaagctttct taggcgagat cgggttaaca ggtgagattc ggcgagtgac ccgtattgag
    40381 caacggatta atgaagcagc aaagcttgga tttaccaagg tctatgctcc taaaaatgct
    40441 ttgcaaggca ttgatatccc tcaaggtatt gaggttgtcg gagtgactac ggttggtcag
    40501 gttttaaagg cagtttttag ctagaggatc agaaactaag agcaaatgag gaggaaattt
    40561 gtcaagaaag tatcccaatc atttgttttt ttaacttttc gaacgatacc gaccgtctaa
    40621 gaggttaatc cagctatttt ccataaaaga tgttaagata agacaaaata acagcaaaaa
    40681 tagctctgct gtttatcaaa aggagtttat tgatgtctta ttttgaacat tttatggctg
    40741 ccaatcaggc ttatgtggcc ttgcatggga cagctcattt gcccttaaaa cccaagacta
    40801 aagtagcgat tgtgacttgt atggattcac ggctacatgt ggcccaagct ctggggctgg
    40861 ctctaggaga tgctcatatt ttaaggaatg ctggcggacg tgtcaccgaa gacatgattc
    40921 ggtcgctggt tatttctcag cagcaaatgg gaacgcgaga gattgtggtt ctccaccata
    40981 cagattgtgg cgcgcagact tttactaatg aaggctttgc caagcatatt catgagcact
    41041 taggtgtgga tgtttcaggg caagatttcc ttcccttcca agatgtggaa gatagtgtcc
    41101 gcgaggatat ggctaagcta agagcctcct ctcttatccc tgatgatgtc gttattaacg
    41161 gtgccgtcta cgatgtggat actggaaaga tgacacaagt aatggaataa tgagtagcca
    41221 agttgcagag ctgaattcag ctctttttta tttttaaaaa ttattgaaaa tattagacaa
    41281 agaaataggg aagcgttata ataattgtat caagttattc atacaaacaa ggagagtaag
    41341 atggtcgaca atagaatgag atttacgatt gatcgaagca tgcaatttcc actagttgag
    41401 attgatctgg aacatggggg atcagtttac ttacaacaag gaagtatggt ttatcatact
    41461 gagaatgtaa ccctgaatac caaattgaat ggtaagggat ctggtttagg aaaattagtt
    41521 ggagccatcg gccgttccat ggtttctggt gaatcaatgt tcattacaca agctatgtca
    41581 gatggagatg gtaaattagc attagcaccc aatacaccag gacagattgt tgctttagaa
    41641 ctaggtgaaa aacaatatcg tctaaatgat ggtgcctttc tagccctaga tggttcagca
    41701 cagtacaaaa tggaacgtca aaatattgga aaagcacttt ttggtggtca aggcggactt
    41761 tttgtcatga caactgaagg ccttggtacc ttacttgcta actcgtttgg atctatcaag
    41821 aaaatcacac ttgatggtgg cacaatgact attgataatg cccatgttgt agcatggagc
    41881 agagaacttg attatgatat tcatttagaa aatggcttta tgcagtcaat tggtacaggt
    41941 gaaggagtta ttaatacctt tagaggtcat ggtgagattt atatccaaag tcttaacctt
    42001 gagcaatttg ctgggactct taaacgttat ctaccaacta gttcaaatta gtcaaaataa
    42061 cataaaatca gctttttagg ctgatttttt tcgcctaagc aagtaaaata tgctataata
    42121 agaaagattt tagaagaagt ctgaaaagat cttggcaagc tcaattcatc atttgttgct
    42181 tgtttttcgt gccatagatt tctgagtgat atatgtaaca ggagaagaag catgtctaaa
    42241 ccaattcgtg tgcgttatgc accaagtcca acagggcttt tacatatcgg gaatgcccgc
    42301 acagccctat ttaattacct ttatgcccgt cgtcacggag gtacttttat cattcgtatt
    42361 gaagatactg accgtaaacg tcatgttgaa gatggtgaac gttctcaact tgaaaaccta
    42421 aaatggttag gaatggattg ggatgaaagc ccagaaacgc atgaaaatta ccgccagtct
    42481 gaacgtctag cactttatca acaatatatt gatcaattgt tagctgaagg aaaagcttac
    42541 aagtcttacg tgactgagga agaattggca gcagagcgtg aacgccaaga agcagctggc
    42601 gaaacgcctc gctatatcaa tgaatttatt ggtatgtcag ctgacgaaaa agctaagtac
    42661 attgcagagc gtgaagcagc aggtatcgtt ccaacagtcc gtcttgctgt taatgagtcc
    42721 ggtatttaca aatggactga catggttaaa ggcgatatcg agtttgaagg tggtaacatc
    42781 ggtggtgact gggttattca aaagaaagat ggctacccaa cttataactt tgccgttgtt
    42841 gttgatgatc atgatatgca aatttctcac gttatccgtg gcgatgacca tattgccaat
    42901 acgccaaaac aattgatggt ctatgaagct cttggctggg aagcgccaga gtttggtcat
    42961 atgactctta tcatcaattc tgaaacgggt aaaaaattat caaaacgcga caccaatacc
    43021 ctccaattca ttgaagatta ccgcaaaaaa ggttatatgc ctgaagctgt ctttaacttc
    43081 atcgcccttc ttggctggaa tcctggcgga gaagaggaaa tcttctctcg tgagcaactg
    43141 attgcccttt ttgatgaaaa tcgccttagc aagtcgccag ctgcctttga ccagaagaaa
    43201 atggattgga tgagcaatga gtatcttaaa catgcggatt ttgaaacagt ttatgccctc
    43261 tgcaaaccat tccttgaaga ggcaggccgt ttgacagaaa aagctgagaa gctagtagaa
    43321 ttatacaaac ctcaattaaa atctgcagat gagattattc cattgactga ccttttcttt
    43381 tctgatttcc ctgaattaac agaagccgaa aaagaagtga tggcaggtga aacagtctcg
    43441 acagtcttgc aagctttcaa ggctaagttg gaagctatgt cagatgaaga cttcaaacca
    43501 gaaaatattt tcccacaaat taaggctgtt caaaaagaaa caggaatcaa agggaaaaac
    43561 ctctttatgc ctattcgtat tgcagtatct ggtgaaatgc atggcccaga attaccaaat
    43621 acgatttatt tattgggacg tgataaatcc attgagcaca tcaaaaacat gctataaggc
    43681 tgtatcgttc acctttattt ttaaacgctt taaggagtta aaaagtcacg acaacgaaag
    43741 attgaagatt aagttcttca gtctttttta tcgttatctg agcttgctac cttggtaaag
    43801 taaaaaatag tatagtttat ttctattttg gagattggat ttgaaagaga ggtggtgaga
    43861 tgcttacgtg ataatgacag taaacggtga ggttttgatt agtgtgattt aaagaaatgg
    43921 tttttatgaa tcaattagtg tacaatattt ttttggtata tgctgaaaga gactagttta
    43981 gtattcactt agctaatcaa ttgtaatcaa ataatattgt aatcattgtc ataaaatatg
    44041 ctaaaataat aaagttggaa aggagaaaaa atggctaata gcgaatatat gtttttatta
    44101 ttatcaatta ttgtctatta tatgacaaaa atttatattt tttcctttct atctgatatc
    44161 acattaccag tttggaaaca actaacgatt ttggctttag ccctattttt caatcagttc
    44221 ccgtatttgt cgccattgct aattgatcct ctattatttt tagttgtttt aaggcaagaa
    44281 accaagcaat tattttcttt gaaagctctt tttttggctg ttgcacctag tgttttggtg
    44341 gatttgctat ctcgatttat gggtacaatc gttatcccct atcttttttt gtcgagtggt
    44401 atttatctgg gtcatattat ctttgacttg cttgcttatc tgctgatttt tccaagtttt
    44461 gctattatta attatatgat tggaaaagat tacaagatga tatgccaatc tggatattcg
    44521 aaacgatcgc ataatttcta tcaaacattg ctgatttttg ttttggttta ttatgtggac
    44581 atttttgtca ttttaggatt tacggacccc tttttacatt ttcatcattc tctttttgtt
    44641 cccacacctt ataagttatt gtttttgatg tttatacttc tttttgttta tcttctatct
    44701 tattttaatc atagttctaa agaatacctt aaaaatgagt tgagaagaga acaacaagct
    44761 tatatgacta acttagagac ttatgggaaa catcttgaga aactctatcg agatgtaaga
    44821 gcttttcaaa gtgattacct gagccgtata gagcgtttag gtcaagccat taagagtgaa
    44881 tccattactc agattcaaga tatttatgcc caaacggttc atgaagctaa cgactactgg
    44941 gatgataaac actataatat ctcgaagctt aggaaaatta atatctcatc gattaagagc
    45001 ttattgtcag ctaaaattat cagtgcggaa aaatcaggta ttgatttgaa tgtggaagtg
    45061 ccagataata taaaagagac ttacattcct gagttggact tactattgtt gatgtctatt
    45121 ttttgtgata acgccattga ggcagctctt gaagcacaac aacctcatat gtcaattgct
    45181 tactttttgt tagatgacta tcagatgttt gttgtgacaa atacgactaa aaaaaaggta
    45241 gacattaaca agatctttga agaaggctat tcttcaaaag gctcagaacg tggtatcggc
    45301 ctttctaatg cgcagcgtat tctcaaaaag tatccttatt tatccttgcg gactaaaagt
    45361 tttgataagg aatttagcca aaccttgacc atgccaaagg aggaggtgga tagatgatgg
    45421 ttatatacag tatggcttta ttctatgcta ccatctttat taacagctgg gtcatttttg
    45481 caaaggtttc tgctattaaa ctaagctgga aacgggttag cattataggc attagttttg
    45541 taattgctaa tatgatattt gacaaagtca ttttgattga ccaactgttt tttattattg
    45601 ttagtttgtt aagtgctccg aaaaagaaat tatttgagca tatgtttaat ggtttcttta
    45661 ctatcttgat tgtcgaatta ctgtttcgcg tcatcggatc tttcttttta ccagctgtct
    45721 taggatttag cattggtcag attaataata accttaagct tttagagtta tgttatcttt
    45781 ttgtattacc aatattttat ctgtttagct acattttcag tattgactta agcttaataa
    45841 ggtttatcag tgaagataag atgaaaaagt gggtattttg gatgaatact gccatgtttt
    45901 cttactactt tttcgcccat tttttggtaa ctgtgcaaag cggatttctt gcactatatt
    45961 tccagtaccg gtctatttta gtatttattt atttagctat ttttatttgg gttattgtga
    46021 aattagatcg atttgctaaa gatcagctgt cacaaaaatt aacacaagca caaaatgaac
    46081 gtattgcgta tcttgaaaat tacaatcaat cgattgagca actttaccga gaaatcagaa
    46141 cagttaaaca tgattctgaa aatattttaa ttagtctaaa agatagtatc gatagtggtg
    46201 atatagatct gattactaga gtttatgaca cggttattca gcaatcgaca acttctatga
    46261 tgcgcacaaa ttatgaaata tcttctttag acaatatcaa agagactgtg attcgcagca
    46321 tcatgaattc caaattgctt gaagctcagt atttgggtat tgaactttat attgagattc
    46381 cagatgttat cgatcattta cctattaagt taatcgactt aattgtactt tttactggac
    46441 tagtggacaa tgctattgag acagccaaag gcagtagacg tcctttttta tctattgcat
    46501 actttaaaca agataacaag caattattta ttattgaaaa tagcacaaaa accaatcgtg
    46561 tggatatagc caaacgcttt gatgctcagc agcagaactc agcccacttt ttgactgttt
    46621 tagatagtta cccccaaata acgctttcga ctaaaagtga ccattatcga ttaagacaat
    46681 tgttagaaat gagataaagt atgatgaaca tttttattct tgaggatgat tttatccagc
    46741 agacacgcat agaatctatc gtagtaggca tcttaaaaga gactagaata ccatgtaatc
    46801 agcttgaagt gttctcgact cctcaaaaat tatttgagag tatccaagaa agaggagacc
    46861 atcagctgta ttttttagat attgaaattg gtgaatatac tcgttgtggg cttgaattag
    46921 ctgcagctat tcgacaaaaa gatcctaatg ccgttattgt gtttgtcacc actcattcag
    46981 aatttgctcc tatttctttt aaatataagg tatctgctct agattttatt gataaagcag
    47041 gtggtcaaaa acagtttaaa gaacaaatcg aagaatgtat ccgatatact tacgatatga
    47101 tgtctagtcg tgagtcaaag gacatgtttt tatttgagac tccacagaca agattaaaat
    47161 tgccttataa ggatatttta tactttgcta cagccacaac tcctcacaaa gtttgtttat
    47221 ggactcagac agaaagatta gagttttatg gtaatctatc tgagattcaa gcagtagcac
    47281 cgaaactttt tttgtgccat agatcctacc ttgtgaatct agataaggtt gttcgaattg
    47341 ataagagtaa gcagctcctt tatttcgaaa atggtgattc ttgtatggta tcacgattaa
    47401 aaatgaaatg tctgtttgaa cggtgggagg ctcttcgcta aagttaagag agcaataaca
    47461 ttttaggacg aaaaagcaac atttcaggaa atgatgctct tattgaagta tttttcgcta
    47521 taataattaa tgtaaataaa gatttacgaa gtcatgagtt tatcgagcaa tcaatcccca
    47581 attcaatcaa aatattgttt tctctctctc cataaacaaa tagtattttt gatatgatgg
    47641 ctcggcagac aaaatgacga tgtcagttgt ctttgtttgg atatcacatt agctggttgt
    47701 aaaatcagta ttaaagcccg gcttgccggg ttttttgata ggtaaataca gggataagta
    47761 gctgacgtct tgtggattct gactttttat ggttgttttc tgaaggttat tcctttgtcg
    47821 aaagaagaac tatactacga aaagatggag tgacaagagg cagttgaagc acaaaaacta
    47881 gaaatagtac agaaagaggc ttaatctaaa agggttaggg ctttttaatt ttttagggga
    47941 tgtggtataa tggtaataat ttagattatg gagttaaatt ttgaagaaga cctatcgtgt
    48001 caagcgtgag aaagatttcc aagccatatt taaggatgga aaaagtacag caaatcgaaa
    48061 atttgtcatt tatcatttaa atagaggcca agaccacttc cgtgtgggta tttctgtcgg
    48121 taaaaaaata ggaaatgcag tcaccagaaa tgcagtcaaa cgaaagatac gtcatgttat
    48181 catggcatta gggcatcagc tgaagtcaga ggatttcgtg gtgattgccc gtaagggtgt
    48241 cgagtctttg gagtatcaag agcttcaaca aaatttacat catgttttaa agttagcaca
    48301 attgcttgag aaaggttttg agagtgaaga aaaacattaa aattgcaaga atagtcccct
    48361 tagttctatt attagtggcc tgtggtcgtg gtgaggtaac ggcacaatca tctagtggtt
    48421 gggaccagtt ggtttactta tttgccagag caattcaatg gctttccttt gatggttcaa
    48481 ttggtgttgg cattattctt tttaccctta ctatccgtct catgctcatg cctttgttta
    48541 atatgcaaat caaatcaagc cagaagatgc aagacatcca acctgagctt agagaattgc
    48601 aaaagaaata cgctggtaaa gacacacaaa cgcggatgaa gttggctgaa gaaagtcaag
    48661 ccctttacaa aaaatatggg gttaaccctt atgccagtct cttacccctc ttaattcaaa
    48721 tgccagttat gattgcccta ttccaagcct tgacacgggt atctttctta aaaacaggga
    48781 ctttcttgtg ggtggaattg gcacaacatg atcatttgta ccttttacca gttttggcag
    48841 ctgtcttcac tttcttgtcc acttggttga ccaatctagc gactaaagaa aaaaatgtca
    48901 tgatgactgt tatgatttat gtgatgccgc taatgatctt tttcatgggc tttaacttgg
    48961 ctagtggagt agtgctctat tggacggtct ccaatgcctt ccaagtggta caactactgt
    49021 tattaaacaa tccttttaag attattgcgg aaagacaacg tcttgccaat gaagaaaaag
    49081 aacgccgtct tcgtgaacgt cgtgctcgta aaaaagcaat gaagagaaaa taggagttta
    49141 ggttatggta ttatttacag gaaaaacagt cgaagaagct atcgaaacag gacttcaaga
    49201 gttagggtta tcacgcctta aagcgcatat caaagtcatt tcaaaagaga aaaaaggttt
    49261 cctcgggttt ggtaaaaagc cagcccaagt tgatattgaa ggtatcagcg acaagacggt
    49321 ttataaggct gataaaaaag ccactcgagg tgttccagag gatattaatc aaaaacatgc
    49381 tcccgcggtc aattctgctg atgtagaacc tgaagaaata aaagccactc aaaagttaga
    49441 agcagaagat accaaagtgg ttcctctcat gcctgaagat agtccagcgc aaaccccttc
    49501 taatcttgct gagacagtca ctgaaacaaa agcacaacaa ccgtcaatcc cagtcgaaga
    49561 atcagaagtg ccccaagatg ctggtaatga tggtttcagc aaagatattg aaaaagctgc
    49621 tcaggaagtg tccgattatg tgactaaaat catctatgaa atggacattg aagctaccgt
    49681 tgaaaccagc aacaatcgtc gccaaatcaa tttgcagatt gaaacgccag aggcgggacg
    49741 tgtgattggt taccatggta aggttttgaa atccttgcag ttgttagctc aaaatttctt
    49801 gcacgaccgc tattcaaaaa atttttcagt atccttgaat gtccatgatt atgtggaaca
    49861 tcgaacagaa accttgattg actttacgca aaaagttgcc aaacgcgtct tggaatctgg
    49921 tcaagattac accatggatc ccatgagtaa cagtgagcgt aaaatcgttc ataaaaccgt
    49981 ttcatccatt gaaggggttg atagttattc tgaaggcaat gaccctaacc gctatgtggt
    50041 agtcagtctt caacgttaga tcctaaaaag aatctttggt agttagttta gctatcgaag
    50101 attttttgta tgaccagctt aaccgtttgt tttactgatc tcattgatca ttgttgctat
    50161 tgataaggtt tccacggtaa gacaaaggaa cagtgtcaaa gaagagacac tttatgaaat
    50221 gaacggcctc ttaaatgaga gagaaactgt tgaaaaacga aaataaatct tgacagtaga
    50281 ccctctttaa gatagaatat tatagtatgt ttagtaactg atatcacaaa tagccggcta
    50341 aacgaataca aaatctatga ggaggtattc actgtgaaac gtacttatca accaagtaaa
    50401 atccgtcgtc aacgtaaaca cggattccgt caccgtatgt caactaaaaa cggacgtcgc
    50461 gtgcttgctg cacgtcgtcg taaaggacgt aaagtattat cagcttaatt gcaaaaaata
    50521 caactaaagt aaaccaagag tgctcgaggc tcttggtttt ttaacgtttt ctaatcggaa
    50581 atttgcaacg tataagtatg gtgtcaactc cttaccttct tatttgttgt atgaaagagc
    50641 attccaaata atagaaaata atataaaaaa tgaaagtaga ttctaaaagt ctcattgctg
    50701 ttgaaagcgc tctatttttt gttataataa ctttgtgaac attattttta ttaaaactaa
    50761 gaaacacaag gagtagaaac tatgcctgat aaaccaacca aagaaaagct catggagcag
    50821 ttaaagggtg ggattatcgt ttcttgtcag gctttgccag gtgagcctct ttattcagag
    50881 actgggggta ttatgccact gatggcaaaa gctgctcaag aagctggtgc tgtcggcatc
    50941 agagctaatt cggttaggga tattaaagaa attcaagcca taacagacct accaattatc
    51001 ggtatcatca aaaaagatta cccgccgcaa gagcctttta ttacggcaac gatgaccgaa
    51061 gtggatcaat tagctgcctt aaatattgca gtgattgcta tggattgtac caagcgtgac
    51121 cgacatgatg gcttggatat tgctagcttt attcgacaag ttaaggaaaa gtaccccaat
    51181 cagcttttga tggcagatat tagtaccttt gatgaaggac tagtggccca tcaggctggc
    51241 attgattttg ttggaaccac cttgtcaggc tacaccccgt atagccgtca ggaagcaggt
    51301 cctgatgtgg cattgataga agctctttgc aaagcaggca ttgctgtcat tgccgaagga
    51361 aagattcatt ccccagaaga agccaagaaa attaatgact taggtgtggc aggtattgtt
    51421 gttggagggg ccatcacaag gcctaaggaa attgcagggc gttttatcga agcgctcaaa
    51481 tcctaatagt ggttgtcaaa ctagaaacac acatcaaaaa aaggagattt tacgatgaac
    51541 atgaagaagt tagcttcatt agcgatgctt ggtgcatctg ttttaggact agcagcttgt
    51601 ggcggaaaga gccagaaaga ggctggtgca agtaaatctg atactgctaa gacagaaatc
    51661 acatggtggg ctttcccggt cttcacgcaa gaaaaagctg aagatggtgt gggaacttat
    51721 gaaaagaaat tgattgctgc ctttgagaaa gctaatccag aaatcaaggt aaaattggaa
    51781 accattgatt ttacatctgg tcctgagaaa atcacaactg ctattgaagc tggaacagct
    51841 cctgatgtcc tctttgatgc tccaggtcgt atcattcaat atggtaaaaa tgggaaattg
    51901 gctgacttga atgacttgtt cacagaagag tttaccaaag atgttaacaa tgacaaattg
    51961 attcaagcct caaaagcagg agatacagct tacatgtatc ctatcagctc tgctccattc
    52021 tacatggcgt tgaataaaaa aatgctcaaa gatgctggcg tccttgacct tgtgaaagag
    52081 ggttggacaa cagatgattt tgaaaaagtc ttgaaagcat tgaaggacaa aggatataac
    52141 ccaggttctt tctttgctaa tggtcaaggt ggtgaccaag gaccacgtgc cttctttgct
    52201 aacctttata gtagtcatat taccgatgac aaagtaacca aatacaccac agatgatgct
    52261 aactctatta aagccatgac caagatttcc aattggatta aagatggttt aatgatgaat
    52321 ggctctcaat acgacggttc agctgatatt caaaactttg cgaatggcca aacttccttt
    52381 accattcttt gggcgcctgc acaaccaggc atccaagcta aattgttaga agctagtaaa
    52441 gtggattacc ttgaaatccc attcccatca gatgatggca aaccagaact agaatacctc
    52501 gtaaatggtt ttgcggtctt taataacaaa gatgaacaaa aagtcgctgc ctctaagaca
    52561 tttatccaat ttatcgctga tgataaagaa tggggaccta aaaatgttgt tcgtacaggt
    52621 gctttccctg taagaacttc ttatggggat ctttacaaag acaaacgaat gaaaaaaatt
    52681 gctgaatgga caaaattcta ctcaccatac tacaacacga ttgatgggtt tactgaaatg
    52741 agaactcttt ggttcccaat ggttcaagcc gtctctaatg gtgatgaaaa gccagaagat
    52801 gctttgaaag ccttcactga aaaagcgaac aagacaatca aaaaaacaca ataagtgttc
    52861 agaacaagtg gcttcttttc acggtacatg tcaaatggtc actggaaagg agcctttcct
    52921 ttttttagga gagattaata gaaaaagagg tatttcaagt gaacgtcaat aaattaaaaa
    52981 tgagagagac gctcatctca tacgctttct tagctccggt cttggttttc tttgtgattt
    53041 ttgtcttgat accgatgatt atgggctttg tgacgagctt tttcaattat tccatgacgg
    53101 attttacctt tgttggtttt gctaattatg ttaggatgtt tcaagatccc attttcatga
    53161 agtcccttat taacaccttg attattgtta ttggttcggt acctgttgta gttttctttt
    53221 ccctctttgt ggcggctaaa acctacgaca aaaatgtagt ggcgcgttcg ttttaccggg
    53281 cagttttctt tctgcctgtt gttaccggaa gtgttgcggt gacggtagtt tggaaatgga
    53341 tctatgatcc gatgtcaggg attttgaatt atgtcttaaa atatgctcat gtgattgaac
    53401 aaaacattag ttggctggga gataagcact gggctttgtt agctattatt gttattttat
    53461 taaccacatc tgttggacag cctattattc tatatattgc tgctatggga aatattgata
    53521 attctttgat ggaagctgcg cgtgtagacg gcgccacaga atttcaggtg ttttggaata
    53581 tcaagtggcc aagtctcctg ccaacaacct tatatattgc tgtcataaca accattaatt
    53641 ccttccaatg ttttgctttg attcaacttt tgacgtctgg agggccaaat tattcaacca
    53701 gtaccctcat gtactatttg tatgaaaagg cctttaagct ctctgaatac ggctatgcca
    53761 acacaatggg tgtattcttg gcagtcatga ttgcaatcat cagctttgct caatttaaaa
    53821 ttttaggtaa tgatgtggaa tattaggagg atattaagat gacgaaaaag aaactaaccg
    53881 catcagatat cttaaccact gtgatgctat gtgttttgac cattttgttt atttttccat
    53941 tttattggat tatgacagga gcatttaagg ctcaagccga taccattatg attccaccgc
    54001 aatggtggcc aaaggcacct actattgaaa attttaaggc cttggtagtg caaaatccag
    54061 ccttaaaatg gttgtggaat agtatcttta tttcggtggc gaccatgttc ttggtttgtg
    54121 gcacttcctc tttggctggc tatgctttgg ccaaaaaacg gttttatggg cagcggcttt
    54181 tgttttcgat ttttattgct gctatggcct tgccaaaaca ggttgttcta gtgcctcttg
    54241 tgcggattgt taattttatg ggaatccatg atactttggc ggctgttatt ttgcctcttg
    54301 tgggctggcc atttggtgtt ttccttatga aacagttctc agaaaatatt ccaaccgagt
    54361 tattggaatc cgccaagatt gatggttgtg gcgagattcg cacctttttc aatgtggctt
    54421 tccctattgt caaaccaggc tttgcagcgc tagcgatttt tacctttatc aatacttgga
    54481 atgattattt tatgcagttg gtgatgttaa cctctcggga aaatttaacg atttcacttg
    54541 gggttgccac tatgcaagct gaaatggcta ctaattatgg cttgattatg gcaggggctg
    54601 ccatggctgc agtgcctatt gtaacggtct ttcttgtctt ccaaaaatca tttacccaag
    54661 gcattactat gggtgctgtg aaaggttaga ctaaataaag cgtgtcacta agcttaatct
    54721 ataggttgct tattaattta ggtgcataca tagataaatc agatgggaag caagtcatgt
    54781 gttaaacgtt taaaagggga attagctttt gtttgtaagc gtatttctag aaaggaagtt
    54841 gtgatttgac atcgaaaaaa cagggacttt tatattctct ttttaatctt gatagtaaat
    54901 ggatgagggc tagcgcagca ctgtttgatt tgctcgtgtt taatctttta tttgtcttgt
    54961 cctgccttcc ccttctaacg attggggttg ctaaaatggc tttgtatgcg agtttgttgg
    55021 attggcgaga aggtcaagtt agtcagcttt ttactactta tagctcttat tttaaaaatt
    55081 attttaaaag agggatgcgc ctaggtctta ttgagctttt gataatgagt atttgtgtct
    55141 tagatctttt cttaattcga aaccaatcag gcctagtttt tcaagggttt aaggtacttt
    55201 gcattgctgt tttatttctg gtggttatac tctttttgta cgcttatcct caggccgtca
    55261 gaaaagagct tcctctttta atactcttta agcgaagttt actgctggca ggaattttct
    55321 tcccatggac gtttgctttt ctagtggtga ttggcctttt ggtttttacc ttgccgttaa
    55381 ccctgttaac cttattttgt ggcttgtctc tactggccac tatgggcatc agtagcctaa
    55441 cctattttta tcttctgatt atggaatccc ttcttaggcg attcccactt aataatgaca
    55501 ttgaataaag gacattacta tgacagatct tacgaaatac caaggcatta ttcctgcctt
    55561 ttatgcttgt tatgatgacc aaggagctat tagccctgag cgtgtgcgtg ccttgaccca
    55621 gtactatatt gacaaagggg ttcaggggct ttacattaat ggctcttctg gagaatgtat
    55681 ttaccagagc gtttttgacc gtcaattggt gttagaaaat gtcatggcag tcgctaaggg
    55741 caagctgacg attattaatc acgttgcctg caacaacact aaagatagta ttgaattggc
    55801 agctcattca gaacgtttgg gcgtggatgc cattgcagct attccgccta tttatttccg
    55861 gttaccagaa tatgcagttg ctgattattg gaatgcgatt tcttcggctg ctcctcacac
    55921 agattttatc atctataata ttcctcaact ggcaggggtt gccttgaccc caagccttta
    55981 taagactatg ttggctaata agcgcgtgat tggggttaaa aactcatcca tgccagtgca
    56041 ggatattcaa accttctgtg cgattggtgg ggacgaccgt attgttttta atggcccaga
    56101 tgaacaattt ctaggagggc gcttgatggg tgctgctgca ggcattggtg gcacctacgg
    56161 ggctatgcca gaattatttt taaggctgaa ccaacttatt gctcacaagg atttagaaaa
    56221 ggccaaggcc cttcaatata ctattaatga gattatcggt gtccttgttt ctgctcacgg
    56281 caatatgtat ggggttatta aagaagtact tcgtattaat gagggtcttg atattggttc
    56341 tgttcgatca cctttagctg agttggtcga ggaagatagg gttatttgcc aacgggctgc
    56401 tgctctgatt aatcaggcta aggaaacctt ttgataagat gcgaggggat aacaaatgaa
    56461 gcattattta gcaattgata ttggtggtac tgctatcaag tatggcttga tttctgaaac
    56521 aggagacctg ttggaaaaag aggaaatggc cactgaggct tataaaggtg gtccctctat
    56581 tttggaaaag gtcaagggct tggtaaagac ctatcaagac caaatggatc tggctggagt
    56641 ggccatttct tctgcaggaa tggttaatcc tgatgaggga gaaatctttt atgccggccc
    56701 tcagattcct aactatgctg gaactcagtt taaaaaagag attgaagaga ctttcgggtt
    56761 accgtgtgaa gtggaaaacg atgttaactg tgctggtcta gccgaagcta tttctggtag
    56821 tgccaaggat tatcctgtgg ctctttgctt gacaattggg acgggaatcg gtggctgttt
    56881 attgtttaat tcccaagttt ttcatggtag tagtcattca gcttgcgaag ttggttacct
    56941 tcatttgtca gatggtcagt ttcaggatct ggcatctacc acagctcttg ttcaagaggt
    57001 ggccttagct tatggggatg acattagcca atgggatggt cgtcgtattt ttgagcaggc
    57061 taaagcgggt gatgcgattt gtatagcagc cattagtaag caggtggatt acttaggaca
    57121 aggtattgct aatatctgct acgttgttaa cccaaatgtg gtggtgcttg gtggcggtat
    57181 catggcgcaa aaagattatt tagctgataa attaaagaca gctcttgata gctacttggt
    57241 ttctagtctt gccaagaaaa ctcagctgaa gtttgctagt catggaaata atgctggtat
    57301 attaggagct tactaccatt ttaaacaaaa gaatgagcga tcctgttcat ttataactct
    57361 tgagaaaatc gaaaataatt tagcgagtag ctaatcttag tggctgtgag tctatatgac
    57421 gtgaagagtt cttgtttaag tatactgggg gaggtgaatg acgacccttt aaaaagaaaa
    57481 caacgccctt tttgctattg tagtctaaag gtcgttattt tctttgtcaa taatagtgtt
    57541 tttgaagatt ttttctttgt gcggtttgtc aatcgctaaa acgtaagcat aaataatgtc
    57601 catcataata agaagaggaa attgtggtga cacacgattc ccataatgta gttggtgggt
    57661 tgatgatacg ggaataatat ctaaggagtc gtcaaattcg gtttgattat ctgttgttaa
    57721 gaggacagtt ttggcccctc gctgactagc ttgatgaagt gctgtgatga cagagtttgt
    57781 tttgccagat aaagaaaaac caaaaacaag gcaattttca ttgacgaggc tatttgccca
    57841 agtaaaacca tcagtgtctg aataagcatc acagattaaa ccaagtcgca taaagcgtag
    57901 cttcatttct cttgctacta gtccagaaga tcctttgcca aagaaataga ctcgctcaga
    57961 agcatcgatc agcttggcta agttcagtaa tttttcctca ttaacgagct cataggtttt
    58021 attaataaga gcatcgtagt ccatcagcac gcgctttgtc aattctaagt gaatagattg
    58081 gaaagtctct tgtgattctt gaagactgtg aaggtaatca aaggcaaaag cacgataacc
    58141 agtaaaacca cacttttttg caaatcgagt caaggcggct tgagagatgt gtagtcgctt
    58201 aactatctcg gatgcggtca actcttgagg tgtcagatcg gttgtaataa aaaaatgagc
    58261 aatccctttt tctaaactgg tcatatgttc caatgatgct tcgattttgg taattaggcg
    58321 gtggttttta ggcatagcaa agcacactcc ttacagttta actatctact agtatagcat
    58381 agatcgctaa cagaaggtag cgaccctttt tgtgatacag atttgttcaa cccactttat
    58441 ttgagtaggt tgtagtattt ttgagggctt atgtaggatc cgactattaa aggtcatttg
    58501 tcaaaaaagt agaaaataga caagtgtcag ctagcaaagg gttttacgat caacctaaac
    58561 ggcagaagtt ctcaccaagt tttctgatgt gattaagatc tttatgttat aataacatca
    58621 tgacaaataa agtagaaaaa ctaactattt ttgataccca tacgcacctg aatgtagcag
    58681 aatttcaagg acatgaagct gaagaattgg ctttggctca agaaatgggc gtggcctacc
    58741 ataatgtggt tggctttgac caggccacta ttagtggagc acttgctctc gcagaccagt
    58801 atcctaacgt gtatgctact attggatggc acccgacaga agcaggctct tattctgaag
    58861 cagttgagga gtctatcgtc tctcaattat cacatcccaa agtgattgcc ctgggtgaaa
    58921 ttggcttaga ctatcattgg atggaggacc ccaaagaggt gcaaatagag gtttttaagc
    58981 gccaaatgca attagcaaaa gaccatgatt tgccttttgt ggtgcacacc cgcgatgcct
    59041 tggaagatac ctatgaagtc atcaaagcag ctggtgttgg ccctcgtgga ggcatcatgc
    59101 attcttactc agggtcatta gagatggctg aacgtttcat tgaacttggc atgatgattt
    59161 ccttttcagg tgtggtcact ttcaaaaagg ctcttgatat tcaagaggca gcgcagcact
    59221 tgcctttgga taagattttg gtggaaacag atgcccctta tcttacacca gttccaaaac
    59281 gtggcaaaca aaatcataca gcttataccc gctatgtggt tgataaaatc gcagagctac
    59341 gggggatgac tgtggaagaa gttgcaaaag caacgactgc taatgcaaag agggtattca
    59401 agcttgactg aaaaaattaa tattcaagag gttcttgttg tagaaggcaa ggacgacacg
    59461 gctaacctac gccgttttta cgaggtggat acctatgaga ctagaggctc tgctatcact
    59521 gaagaagatt tagaacgaat caatcgccta aacgatttgc gtggtgttat cgttttaaca
    59581 gacccagatt ataatggtga gcgcattcgt aagctcatta tggctgctgt gccaacagct
    59641 cgtcatgtct ttttaaaccg aaacgaggcg gttccgagtt ctaagagtaa gggtcgttcc
    59701 ttaggggttg aacatgccag atttgaggat ctccaaaagg cacttgctca tgtcactcag
    59761 caatatgatg atgagtctta ttttgacatt cgtcaaacag acctgattcg tctagggctt
    59821 ttaatggcgt cagatagccg taaacgcagg gaatacttgg gtgaaaagct ccgcatcggt
    59881 tatgccaacg gcaaacaact gctcaagcgc ctcgaattat ttggcattac cctagcagaa
    59941 gtggaagaag tgatggagac atatggggag taaagagtac aataaaatat aacagcccca
    60001 ttaactgaat ggcgtgtctt ggcaaaaaag tttaggctag tggttcaaat gccaaaaaga
    60061 aagtgatcat aaaaagaaga gaatatatga gaattgcaga ttatagcgtg accaaggctg
    60121 tccttgatcg tcacggattt acctttaaga aatcttttgg tcagaacttt ttgaccgata
    60181 ccaatatttt acagaaaatc gttgacacgg ctgagattga tcagaatgtc aatgttatcg
    60241 agattggtcc tggaattggg gctttgacgg aatttttggc agaaaatgct gctgaagtga
    60301 tggcttttga gattgatgac cgcttggtgc cgattttggc agataccttg cgcgattttg
    60361 ataatgtgca agtggtcaat caagatattt taaaagctga tttgcagacc caaatcaagc
    60421 agtttaaaaa tcctgatttg cccattaagg tggtagctaa cctgccttac tacatcacaa
    60481 cgcctattct catgcacttg attgagagca agattccatt ccaagagttt gtagtcatga
    60541 tgcagcgtga agtggcagat cgtatctcgg ctgagccaaa cactaaagct tatggttcct
    60601 tgtccattgc ggtgcagtat tacatgactg ccaaggttgc cttcattgtg ccgcgcaccg
    60661 tctttgtacc tgcaccaaat gtcgatagtg ctatcctcaa aatggtgcgt cgcgaccagc
    60721 ctttgattga gattaaggac gaagatttct ttttcagagt atctcgtctc agttttgtcc
    60781 atcgtcgcaa gaccctgtgg aataacttga ctagccattt tgggaagtct gaagacatca
    60841 agactaaact tgaaaaaggt ctggcactag cagatatcaa gccttctatt cgtggtgagg
    60901 ccttgtcgat tcaagatttt ggcaaattag ctgatgcttt aaaagaagtt ggattataaa
    60961 agctttcccc cggtgacaat aaaaaaaatt cccttgtaga caaaacagaa atgttcagtt
    61021 cagggggatt tttcttattg aagctggccg ttaaggtatc gcagtgcaga gctagttttt
    61081 ttaatacccc ggaaaaaagg ggcaattaac aagagcgtga ctatagcggt acggttagac
    61141 tctttttcgt aaatagcaaa ggtcttctta aaattcatat cgtttcctac ctcaaaaatc
    61201 atcagtgatc tgatttttag ttgataaaat attctatttt taaaaagcag tgacctaaat
    61261 gatagccagt ggtctagaga atcttgacag ttttttaagg cgagtgaaac ttagagtcaa
    61321 atgctgattt gggagcggtt ttctgatata atagagttat tatagtaggg caaaggagca
    61381 cagttgcaag gtaaaatcat taaatctctg gctggttttt attacgtgga gtcagaagga
    61441 caggtatatc agacgcgagc gcgtggtaat tttaggaagc gcggtgagac accttatgtt
    61501 ggagatatcg tggatttctc agcagaggac aactctgaag gttatatttt agcgattcat
    61561 cctcgtaaaa acagtttggt aagacctcct atcgtcaata ttgaccaagc agtggttatt
    61621 atgtctgcta aagaaccaga atttaacagc aatcttctag accgctttct catcttgctt
    61681 gaacacaaag ccattcatcc agtggtttat atctctaaga tggacttatt agatagtccc
    61741 gaggagatta aggctattgg tcgacagtat caggcaatcg gttacaattt tgtgaccagt
    61801 cttgaggaat tgttgccttt gctagctgat aaaattaccg tctttatggg acaaacaggt
    61861 gttggaaaat caacccttct caaccgaatc gcccccgaat tggctcttga aacaggagaa
    61921 atctcagata gtctagggcg tggtcgtcac accacccgag ctgtgagttt ttacaatacc
    61981 catggcggaa aaattgcgga tacgccaggt ttctcatcat tagactatga tattgctaat
    62041 gctgaagatt tgaacgaggc ttttccagag ctgcgccggc tgagtcataa gtgtaagttt
    62101 agatcctgta cccataccca cgaacccaag tgtgctgtca aggcagcgct tgagacggga
    62161 gagttgtggc cagttcgtta tgagcattac ctgcaatttc tcagtgaaat tgaaaaccgt
    62221 cgtgaaacat ataaaaaagt tatcaaaaga aagtaggtct actccatgtc aactctaaaa
    62281 attgccccat ctattctagc agctgattat gctaattttg cttctgagct agctcgtatt
    62341 gaagaaacag atgccgaata tgttcacatt gacattatgg atggtcaatt tgttcctaac
    62401 atcagttttg gtgcagatgt tgtggcaagt atgagaaagc acagtaaatt ggtctttgat
    62461 tgccatctaa tggtggttga tcctgaacgc tatgttgagg cttttgcaca agctggtgct
    62521 gatatcatga ccattcacac agaaagtact cgtcatattc atggagccct tcaaaaaatc
    62581 aaggcagctg gcatgaaagc aggggtagtg attaatccag gaactcctgc aacagcccta
    62641 gaacctttgc tagacttagt tgaccaagtc ctcattatga cagtcaaccc aggttttggg
    62701 ggtcaggctt ttatcccaga atgtttagaa aaagtggcta ccgtagccaa atggcgagat
    62761 gaaaaaggat tgtcctttga cattgaggtt gatggcggag tagacaataa gaccattcgt
    62821 gcttgttatg aagcaggggc caatgtcttt gtggcaggtt cttacctttt caaggccagt
    62881 gacctagtga gccaagtcca aaccttaagg acggccttga atgtctaaag ttgctctttt
    62941 tgcgggagga gatctctctt atatcagccg tgattttgat tattttgtcg gtattgatag
    63001 agggagccta tttttattag aaaatgggct tcctttgaat atggctgttg gtgattttga
    63061 ttcggtttcc caaaaagcgt ttacggatat aaaagagaag gcagagcttt ttattactgc
    63121 tcatccagaa aaaagtgata cggatacgga attagccctt aaagaggtct ttgctcgttt
    63181 tcctgaggcg gaagtgacca tttttggggc ttttgggggt cgaatggacc acctcttatc
    63241 caatattttt ttgcctagcg accctggtat tgctcccttt atggcacaaa tcgccttgcg
    63301 tgaccaacaa aatatgatta cctaccgccc ggcaggtcag caccttatcc atcaagaaga
    63361 agggatgacc tatgtggcat ttatggcaga aggagaagct gacttgacca ttactggtgc
    63421 taaatttgag ttgacgcaag ataatttttt caaaaagaaa atctattcca gtaatgcctt
    63481 tatccatcaa cctattacag ttagtttgcc aagtggctac ttgattatta ttcaaagtaa
    63541 agattggagt tagtatggac cttatcttgt tccttttggt cttggttctc ttaggtttag
    63601 gggcttatct gttgttcaaa gttaatggcc ttcaacatca gcttgcccaa accctagaag
    63661 gcaacgcgga taatttgtct gaccaaatga cctaccagtt ggatacagct aacaagcaac
    63721 aattgttaga gctaacacag ctgatgaacc gacaacaagc agacctttac caacaattaa
    63781 cagatattcg tgacgtcttg caccgtagtt tgtctgatag tagggaccgg tctgacaaac
    63841 gcttagaaga aattaaccag caggtcaacc aatcgctcaa gaatatgcaa gaatctaacg
    63901 aaaaacgttt ggaggaaatg cgccagatcg ttgaagaaaa attggaagaa accttaaaaa
    63961 atcgtctgca cgcctctttc gattctgtat ccaagcaact agaaagtgtc aataaaggct
    64021 tgggagaaat gcgtagcgtg gctcaagatg tgggtacttt aaataaggtt ttgtccaata
    64081 ccaaaacacg aggcatttta ggcgaacttc aactaggcca aatcattgag gatatcatga
    64141 catcaagcca gtacgaaaga gaatttgtaa cggttagtgg ttctagtgaa cgtgtagaat
    64201 atgcgattaa gctcccagga aatggtcaag gcggttatat ttacctaccg attgactcaa
    64261 aattccctct tgaagattat taccgattag aagatgctta cgaagttggt gataaactgg
    64321 ccatcgaggc tagccgaaaa gcacttctgg cagctatcaa acgctttgcc aaagacattc
    64381 ataaaaagta cttgaacccc ccagagacga ccaatttcgg agttatgttc ttaccaacag
    64441 aaggtcttta ttcagaagtg gtcagaaatg cggctttctt tgatagcctt cgtcgggaag
    64501 aaaatattgt ggttgcaggc ccttcgaccc tgtctgcttt gctcaattcc ttatctgttg
    64561 gtttcaagac ccttaatatc caaaaaaatg ctgatgacat cagtaaaatt ttgggcaatg
    64621 tcaagttaga attcgataaa tttggcggcc tgcttgccaa ggctcaaaag caaatgaata
    64681 cagctaataa tacgctggat cagctcattt caacaaggac aaatgccatt gttcgagcct
    64741 tgaataccgt tgaaacttat caagaccaag caacaaaatc tctcttgaac atgcccttat
    64801 tagaagagga aaataatgaa aattaatcaa atgaaaaaag accagctttt tgaagggttc
    64861 tacctcatta agtcggcaga ggttcgtaag acaagggctg gtaaagattt tattagc
//
LOCUS       DAXMQE010000007        63134 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.007, whole genome shotgun sequence.
ACCESSION   DAXMQE010000007 DAXMQE010000000
VERSION     DAXMQE010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 63134)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 63134)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..63134
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.007"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            110..3184
                     /locus_tag="ACF4ZO_000480"
     CDS             110..3184
                     /locus_tag="ACF4ZO_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFD5486056.1"
                     /translation="MTKGIRFQLLGSPHIFLDDKEQFFAFAKANALLYYLVVNGSVSR
                     EVAASLLWENKNTQTAKKNLRNAIYQVNKVLQADVIICPNRNLLVLNKTLDIKTDINL
                     FLADPLAHLELYQGEFLQGFYLKSGEEFDLWVSKMRMQYEQVYLKACYQKIEEKLSLD
                     AIEDVEEHLKQLIERDEFEEKNYQLLMRLYQQGNCPGKVIETYYQLANVLDKELGIQP
                     SLQSQQIYQEVVAKDRNERKIKYFLRNSNHFLGRIDEIKQLENYFANCLACQEVGALL
                     LIGDTGIGKRTLARQVLANQTQTFQIVTAKCFREEAMDSLLPWRNILDGLGDLVIQNR
                     LLTTKAWKAALKRCFPAATIFQEDNNQPFIKDHTSLLVSFIVDILQHLAEIKALVILI
                     EDCHWMDEDSLTLLQRVMNQLVHYPIAFVLTKHLGTTPELGLCLNALMSQGRLESICL
                     EPFNRQESLAYISSQLGSQPVTEEEMEHLYQASQGNPFFLSEYTQALLRHEKFVPLTP
                     AIKAKLGLKLANLSSRDDALLNYLSCCRRPIPLNTLAQLMLLPLEEVIEMVDNLGHYY
                     ILVEESVGEEVLISFRQRIIQLYSYDRLSLSKRRLLHGQIAKRLEDLLPILTPSPHLL
                     DDIAYHYQESRQVIKALEYNLNYLDATLPFQHELFPIYSKSIGSLEKSDRDHQRLMEE
                     QFDKIRQSIADLELTYDNNRDFQQLLIRFSYLEGRYDIRTGRYQEGIKHIQKVIALAT
                     ELKQPSFLLEGYRQLIHYCIQVENKPEMRYYTSLSLEAAVAANHFEAIAISLRLNGLY
                     HLIIGELNEAERLLQQSIDFFKVTPGLQANYATQIAAALDYLGEIAQIRYQFEKAVAY
                     QKQAIALTENKPAELSVSIFYIGLGISYFYLADFEQAEQILSLAKEALVNHSYPWKET
                     QLEIYLAMIQWKKGNYQPALTLLDYRETLMSRYRNPRDKGLVFYLMAVVKYQLIFQGA
                     TLSQQEKEMADHLLSESFEYYYEIASTNLNPYRDCHLVSELDGLRQQFSSNN"
     gene            complement(3248..4234)
                     /gene="hutG"
                     /locus_tag="ACF4ZO_000481"
     CDS             complement(3248..4234)
                     /gene="hutG"
                     /locus_tag="ACF4ZO_000481"
                     /EC_number="3.5.3.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050415 - formimidoylglutamase activity
                     [Evidence IEA];
                     GO_process: GO:0019556 - L-histidine catabolic process to
                     glutamate and formamide [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formimidoylglutamase"
                     /protein_id="HFD5486057.1"
                     /translation="MLEDYYPSTTSYYHGGIDDDLYTAKWGMVMTFLDLNDSSLTPFE
                     GTHFALIGFKSDKGVYINNGRVGAVESPAAIRTQLAKFPWHLGNQVMVYDVGNIDGPN
                     RSLEQLQNSLSKAIKRMCDLNLKPIVLGGGHETAYGHYLGLRQSLSPSDDLAVINMDA
                     HFDLRPYDQTGPNSGTGFRQMFDDAVADKRLFKYFVLGIQEHNNNLFLFDFVAKSKGI
                     QFLTGQDIYQMGHQKICRAIDRFLEGQERVYLTIDMDCFSVGAAPGVSAIQSLGVDPN
                     LAVLVLQHIAASGKLVGFDVVEVSPPHDIDNHTANLAATFIFYLVQIMAQHS"
     gene            complement(4420..5961)
                     /gene="hutH"
                     /locus_tag="ACF4ZO_000482"
     CDS             complement(4420..5961)
                     /gene="hutH"
                     /locus_tag="ACF4ZO_000482"
                     /EC_number="4.3.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004397 - histidine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006548 - L-histidine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine ammonia-lyase"
                     /protein_id="HFD5486058.1"
                     /translation="MTRVINLDGESLTIEDVIAIARQGVACRIDDSAIEAVNASRKIV
                     DDIVSEKRVVYGVTTGFGSLCNVSISPEDTVQLQENLIRTHASGFGDPLPEDAVRAIM
                     LIRINSLVKGYSGIRLSTIEKLLELLNKGVHPYIPEKGSLGASGDLAPLAHMVLPMLG
                     LGKAYYKGELLSGQEALDKAGIDKISLAAKEGLALINGTTVLTAIGALATYDAIQLLK
                     LSDLAGALSLEVHNGITSPFEENLHTIRPQSGQLATARNIRNLLEGSQNTTVATQSRV
                     QDPYTLRCLPQIHGASKDSIAYVKSKVDIEINSVTDNPIICKDGHVISGGNFHGEPMA
                     QPFDFLGIAISEIGNVSERRVERLVNSQLSKLPSFLVKYPGLNSGFMITQYACASLAS
                     ENKVLAHPASVDSIPSCENQEDFVSMGTTAARKAFEILKNSRRIVATEIMAACQALDL
                     KPENHELGKGTKVAYDLFRKEVNFIEHDKHIEIYDELNKASAVIEDPSFLEAVEQAVE
                     LSIQF"
     gene            complement(5972..7315)
                     /locus_tag="ACF4ZO_000483"
     CDS             complement(5972..7315)
                     /locus_tag="ACF4ZO_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HFD5486059.1"
                     /translation="MASNHMNEQEREQAKFSLSGATLYGINAVIGSGIFLLPRAIYKG
                     LGPASIAVMFGTAILTIMLAVCFAEVSGYFGKNGGAFQYSKRAFGDFIGFNVGFLGWT
                     VTIFAWAAMAAGFARMFIITFPAFEGWHIPLSIGLIILLSLMNIAGLKTSKIVTITAT
                     IAKLIPIVAFCACTLFFIKNGLPNFTPFVQLEPGTNLLGAISNTAVYIFYGFIGFETL
                     SIVAGEMRDPEKNVPRALLGSISIVSVLYMLIIGGTIAMLGSQIMMTNAPVQDAFVKM
                     IGPAGAWMVSIGALISITGLNMGESIMVPRYGAAIADEGLLPAAIAKQNQNGAPLVAI
                     LVSGAIAIVLLLTGSFENLAKLSVVFRFFQYIPTALAVMKLRKDAPDANVIFRVPFGP
                     IIPILAVIVSLVMIWGDNPMNFVYGAVGVIIASSVYYLMHGRSHQMDQMPPKEQI"
     gene            complement(7535..8131)
                     /locus_tag="ACF4ZO_000484"
     CDS             complement(7535..8131)
                     /locus_tag="ACF4ZO_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HutD family protein"
                     /protein_id="HFD5486060.1"
                     /translation="MTTVTIKTPADYTQTDWSGGETNQLFLYPEKGDYKERTFSYRLS
                     TATVALRQTTFTRLDGYHRILMSLDKPITLSDLSHAKEISLAPFEPYAFEGDTRIVSR
                     GTCQDINLMYDDHYQGQLLPVWSDTLFEAPKADCQLLYALSKLTYSVTNQANQELEAN
                     HLLVIEQEASLSDLKVCPNQTSPAQTPVAVWAGLWYKT"
     gene            complement(8153..9826)
                     /locus_tag="ACF4ZO_000485"
     CDS             complement(8153..9826)
                     /locus_tag="ACF4ZO_000485"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004329 - formate-tetrahydrofolate ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HFD5486061.1"
                     /translation="MVLSDIEIANSVTMEPISKVADQLGIDKETLCLYGKYKAKIDAR
                     QLVALKDKPDGKLILVTAISPTPAGEGKTTTSVGLVDALSAIGKKAVIALREPSLGPV
                     FGVKGGAAGGGHAQVVPMEDINLHFTGDFHAIGVANNLLAALIDNHIHHGNSLGIDSR
                     RITWKRVVDMNDRQLRHIVDGLQGKVNGVPREDGYDITVASEIMAILCLSENISDLKA
                     RLEKIIIGYNFQGEPVTAKDLKAGGALAALLKDAIHPNLVQTLEHTPALIHGGPFANI
                     AHGCNSVLATKLALKYGDYAVTEAGFGADLGAEKFIDIKCRMSGLRPAAVVLVATIRA
                     LKMHGGVPKADLATENVQAVVDGLPNLDKHLANIQDVYGLPVVVAINKFPLDTDAELQ
                     AVYDACDKRGVDVVISDVWANGGAGGRELAEKVVALAEQDNQFRFVYNEDDSIETKLT
                     KIVTKIYGGKGIKLTPTAKRELAELERLGFGNYPICMAKTQYSFSDDAKKLGAPTDFI
                     VTISNLKVSAGAGFIVALTGAIMTMPGLPKVPASETIDIDEEGNITGLF"
     gene            complement(9844..10470)
                     /locus_tag="ACF4ZO_000486"
     CDS             complement(9844..10470)
                     /locus_tag="ACF4ZO_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0044237 - cellular metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cyclodeaminase/cyclohydrolase family protein"
                     /protein_id="HFD5486062.1"
                     /translation="MGLVDLSLTDFAKVLGSDAPAPGGGSAAALSGANGISLTKMVCE
                     LTLGKKKYADYQDIIEDLHTKSSRLQQDLLDAIDKDTEAFNLVSDVFDMPKETDEDKA
                     ARRTAMQEALKTAAQSPFEMMTLMVEALEITATAVGKSNTNAASDLGVAALNLKAGLQ
                     GAWLNVLINLSGIKDEDFVTDYRQKGQALLDKGCHLADDIYTKILDIV"
     gene            complement(10481..11380)
                     /gene="ftcD"
                     /locus_tag="ACF4ZO_000487"
     CDS             complement(10481..11380)
                     /gene="ftcD"
                     /locus_tag="ACF4ZO_000487"
                     /EC_number="2.1.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003005485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030409 - glutamate formimidoyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0030412 - formimidoyltetrahydrofolate
                     cyclodeaminase activity [Evidence IEA];
                     GO_process: GO:0019556 - L-histidine catabolic process to
                     glutamate and formamide [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate formimidoyltransferase"
                     /protein_id="HFD5486063.1"
                     /translation="MAKIVECIPNFSEGQNQAVIDGLVATAKSIPGVTLLDYSSDASH
                     NRSVFTLVGDDQSIQEAAFQLVKYASENIDMTKHHGEHPRMGATDVCPFVPIKDITTQ
                     ECVEISKQVAERINRELGIPIFLYEDSATRPERQNLAKVRKGQFEGMPEKLLEEDWAP
                     DYGDRKIHPTAGVTAVGARMPLVAFNVNLDTDNIDIAHKIAKIIRGSGGGYKYCKAIG
                     VMLEDRHIAQVSMNMVNFEKCSLYRTFETIKFEARRYGVNVIGSEVIGLAPAKALIDV
                     AEYYLQVEDFDYNKQILENHLLG"
     gene            complement(11468..13498)
                     /locus_tag="ACF4ZO_000488"
     CDS             complement(11468..13498)
                     /locus_tag="ACF4ZO_000488"
                     /EC_number="4.2.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002914331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016153 - urocanate hydratase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="urocanate hydratase"
                     /protein_id="HFD5486064.1"
                     /translation="MSFYSETDIAAAMTVKLDDVLPEKTVFKEGIRRAPDRGFRLTQA
                     QTEIALKNALRYVPTKFHEEVIPEFLEELKTRGRIYGYRFRPKDRIYGKPIDEYKGNC
                     TAAKAMQVMIDNNLSFEIALYPYELVTYGETGSVCANWMQYCLIKKYLEVMTDEQTLV
                     VESGHPVGLFQSKPEAPRVIITNGLLVGEYDNMKDWEIAEEMGVTNYGQMTAGGWMYI
                     GPQGIVHGTFNTLLNAGRLKLGVADDGDLTGKLFISSGLGGMSGAQGKAAEIAKAVAI
                     IAEVDQSRIETRHSQGWISQIAESPEEALQLAQKAIDAKESTSIAYHGNIVDLLEYVN
                     DKQIHVDLLSDQTSCHNVYDGGYCPVGISFDERTRLLTEDKDTFHQMVDDTLARHFEA
                     IKTLTENGTYFFDYGNAFMKSVYDSGITEISKNGRNDKDGFIWPSYVEDIMGPMLFDY
                     GYGPFRWVCLSGKHEDLVATDKAAMEAIDPDRRYQDRDNYNWIRDAEKNQLVVGTQAR
                     ILYQDCIGRVTIALKFNELVRKGKIGPVMIGRDHHDVSGTDSPFRETSNIKDGSNVTC
                     DMAVQCYAGNAARGMSLVALHNGGGTGIGKAINGGFGLVLDGSERIDEIIKSAIAWDT
                     MGGVARRNWARNEHAIETAIEYNRLHAGTDHITIPYLADDDLVTSAVNQLFQ"
     gene            13789..15054
                     /gene="hutI"
                     /locus_tag="ACF4ZO_000489"
     CDS             13789..15054
                     /gene="hutI"
                     /locus_tag="ACF4ZO_000489"
                     /EC_number="3.5.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016812 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds, in cyclic amides
                     [Evidence IEA];
                     GO_function: GO:0050480 - imidazolonepropionase activity
                     [Evidence IEA];
                     GO_process: GO:0019556 - L-histidine catabolic process to
                     glutamate and formamide [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="imidazolonepropionase"
                     /protein_id="HFD5486065.1"
                     /translation="MVADVLLTHFNQLFCLNDPGHPLTGQEMKKATIVEDGYIAIKDG
                     LIVALGSGEPDAELVGPQTIMRSYKGKIATPGIIDCHTHLVYGGSREHEFAKKLAGVP
                     YLDILAQGGGILSTVRATRSASFDNLYQKSKRLLDYMLLHGVTTVEAKSGYGLDWETE
                     KRQLDVVAALEKDHPIDLVSTFMAAHAIPEEYKGNPKAYLDVIIKDMLPVVKEKNLAE
                     FCDIFCEKNVFTADESRYLLSKAKEMGFKLRIHADEIASIGGVDVAAELSAVSAEHLM
                     MITNDGIAKLIGAGVIGNLLPATTFSLMEDTYAPARKMIDAGMAITLSTDSNPGSCPT
                     ANMQFVMQLGCFMLRLTPIEVLNAVTINAAYSVNRQERVGSLTVGKEADIAIFDAPNI
                     DYLFYFFATNLIHQVYKKGQLTVDRGRIL"
     gene            complement(15112..16644)
                     /gene="ahpF"
                     /locus_tag="ACF4ZO_000490"
     CDS             complement(15112..16644)
                     /gene="ahpF"
                     /locus_tag="ACF4ZO_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008785 - alkyl hydroperoxide reductase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0000302 - response to reactive oxygen
                     species [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HFD5486066.1"
                     /translation="MALSPDIKEQLAQYLTLLEADLVLQVSLGDNEQSQKVKDFVEEI
                     AAMSERISIENITLDRQPSFKVAKKGHDSGVVFAGLPLGHELTSFILALLQVSGRAPK
                     VDQDVIDRIKAIDRPLHFETYVSLTCHNCPDVVQALNIMSVLNDKISHTMVEGGMFQD
                     EVKAKGIMSVPTVFLDGEEFTSGRATIEQLLEQIAGPLSEEAFADKGLYDVLVIGGGP
                     AGNSAAIYAARKGLKTGLLAETFGGQVMETVGIENMIGTLYTEGPKLMAEVEAHTKSY
                     DVDIIKAQLATSIEKKENIEVTLANGAVLQAKTAILALGAKWRNINVPGEDEFRNKGV
                     TYCPHCDGPLFEGKDVAVIGGGNSGLEAALDLAGLAKHVYVLEFLPELKADKVLQDRA
                     ADTANMTIIKNVATKDIVGDDHVTGLNYTERDSGEDKHLDLEGVFVQIGLVPNTAWLK
                     DSGVNLTDRGEIIVDKHGSTNIPGIFAAGDCTDSAYKQIIISMGSGATAAIGAFDYLI
                     RQ"
     gene            complement(16665..17225)
                     /gene="ahpC"
                     /locus_tag="ACF4ZO_000491"
     CDS             complement(16665..17225)
                     /gene="ahpC"
                     /locus_tag="ACF4ZO_000491"
                     /EC_number="1.11.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002273221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0102039 - NADH-dependent peroxiredoxin
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit C"
                     /protein_id="HFD5486067.1"
                     /translation="MSLIGKEIAEFSAQAYHDGKFITVTNEDVKGKWAVFCFYPADFS
                     FVCPTELGDLQEQYETLKSLGVEVYSVSTDTHFVHKAWHDDSDVVGTITYPMIGDPSH
                     LISQAFEVLGEDGLAQRGTFIVDPDCIIQMMEINADGIGRDASTLIDKIHAAQYVRKH
                     PGEVCPAKWKEGAETLTPSLDLVGKI"
     gene            17632..17702
                     /locus_tag="ACF4ZO_000492"
     tRNA            17632..17702
                     /locus_tag="ACF4ZO_000492"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:17664..17666,aa:Cys,seq:gca)
     gene            18211..18414
                     /locus_tag="ACF4ZO_000493"
     CDS             18211..18414
                     /locus_tag="ACF4ZO_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFD5486068.1"
                     /translation="MAQGTVKWFNAEKGFGFISTENGQDVFAHFSAIQTSGFKTLEEG
                     QKVAFDVEEGQRGPQAVNITKLA"
     gene            18610..19071
                     /locus_tag="ACF4ZO_000494"
     CDS             18610..19071
                     /locus_tag="ACF4ZO_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HFD5486069.1"
                     /translation="MPTKNTSDSIEEYIKELLAKSGIAEIKRSMLADSFQVVPSQINY
                     VIKTRFTESRGYEVESKRGGGGYIRIAKVHFSDKHHLIGNLMATIEDCISEQVFTDSI
                     QLLFDEHLLTEREGNIILAVASDDVLGTDGSTIRARMLYRLLQRIDRKGSN"
     gene            19071..21515
                     /locus_tag="ACF4ZO_000495"
     CDS             19071..21515
                     /locus_tag="ACF4ZO_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HFD5486070.1"
                     /translation="MIMYSTKMQDIFRQAQFQAARFDSHCLETWHVLLAMVAVDNSLA
                     NMILSEYDAQVAIEEYEAAAILAMGKTPKEQLSRVDFRPQSKTLTNLLAFAQAISQIT
                     RDQEVGSEHVLFAILLNPDIMASRLLEIAGYQIKDNGNGQPRLADLRKAIERHAGYSK
                     EMIKAIHELRKPKKTKTQGTFSDMMKPPSTAGELSDFTRDLTEMARQGLLESVIGRDQ
                     EVSRMIQVLSRKTKNNPVLVGDAGVGKTALAYGLAQRIANGAIPYELKEMRVLELDMM
                     SVVAGTRFRGDFEERMNQIIDDIEADGQIILFVDELHTIMGSGSGIDSTLDAANILKP
                     ALSRGTLHMVGATTQEEYQKHIEKDAALSRRFAKILIEEPNTEDAYQILMGLKLSYET
                     YHNVSISNEAVKTAVKMAHRYLTSKNLPDSAIDLLDEASAAVQNMVKKSAPETLTPID
                     QALINGDMKKVSRLLAKEAKGQMRKPTPVTEDDILATLSKLSGIPLEKLTQADSKKYL
                     NLEKELHKRVIGQDAAVTAISRAIRRNQSGIRTGKCPIGSFMFLGPTGVGKTELAKAL
                     AEVLFDDEAALIRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTQKVRNKPYSVLLF
                     DEVEKAHPDIFNVLLQVLDDGILTDSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFG
                     VKDIHQDHQAMEKRILEELRKTYRPEFINRIDEKVVFHSLTQDNMRDVVKIMVQPLIT
                     TLAEKGITLKIQPLALKHLSEVGYDEHMGARPLRRTLQTEIEDKLSELILSRELTSGH
                     TLKIGLSHGKLTFHIA"
     gene            21693..21983
                     /gene="groES"
                     /locus_tag="ACF4ZO_000496"
     CDS             21693..21983
                     /gene="groES"
                     /locus_tag="ACF4ZO_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HFD5486071.1"
                     /translation="MLKPLGDRVVVRFDDEKEQTVGGFVLAGTHKESTRKATVLAVSE
                     TGVRTITGDSVLPSVSVGQEVLVENGHDLEVTVDDEKVSIIRESDIIAIVTK"
     gene            22019..23650
                     /gene="groL"
                     /locus_tag="ACF4ZO_000497"
     CDS             22019..23650
                     /gene="groL"
                     /locus_tag="ACF4ZO_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001029975.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0140662 - ATP-dependent protein folding
                     chaperone [Evidence IEA];
                     GO_process: GO:0042026 - protein refolding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HFD5486072.1"
                     /translation="MAKDIKFSADARAAMVRGVDMLADTVKVTLGPKGRNVVLEKAFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVHEG
                     LKNVTAGANPIGIRRGIETATATAVEALKAIAQPVSGKEAIAQVAAVSSRSEKVGEYI
                     SEAMERVGNDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDNEKMVADLENPFI
                     LITDKKVSNIQDILPLLEEVLKTNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATMTALGQAAKITVDKDSTVIVEGS
                     GSSEAIANRIALIKSQLETTTSDFDREKLQERLAKLAGGVAVIKVGAPTETALKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALITVIEKVAALELEGDDATGRNIVLRALEEPVRQ
                     IALNAGYEGSVVIDKLKNSPAGTGFNAATGEWVDMIKTGIIDPVKVTRSALQNAASVA
                     SLILTTEAVVANKPEPAAPAPAMPAGMDPGMMGGF"
     gene            23852..24146
                     /locus_tag="ACF4ZO_000498"
                     /pseudo
     CDS             23852..24146
                     /locus_tag="ACF4ZO_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880886.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(24189..24558)
                     /locus_tag="ACF4ZO_000499"
                     /pseudo
     CDS             complement(24189..24558)
                     /locus_tag="ACF4ZO_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920900.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
     gene            complement(24852..26352)
                     /locus_tag="ACF4ZO_000500"
                     /pseudo
     CDS             complement(24852..26352)
                     /locus_tag="ACF4ZO_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889202.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0016805 - dipeptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="C69 family dipeptidase"
     gene            26599..28239
                     /locus_tag="ACF4ZO_000501"
     CDS             26599..28239
                     /locus_tag="ACF4ZO_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HFD5486073.1"
                     /translation="MTKPFHHKKLKQITIIAATSLFLFLIGGAFYYSKNHCINAYLKA
                     RSAQSGPVFENIKAYLVWDDTNEQITNDEAMYTKFRRYSQKELRQKKQDLKAASQDSA
                     VQVKSVGRRFWIFPDYRIAIKPMDLTIKTNVPQADVLLNQKKVAVSDSEQFSVKLDRL
                     PTAEYTASIRGKHNGRNIKVNKSYDGDNPVLDLSVSFRTFLVTSNAKQGDLYFDDNHI
                     GTLKDGQLQVEDYPVTENAQAYMKTTFPDGELRSQKYALADVEEGATLEILVTDLLEE
                     DKAGELLVSAFDQLMHYLSTGQDSSNLRSVFEAGSSNAFYRGLKESIKAKFQTDTRKA
                     SRLNIPSILLTTMTQVGKTTYVLDFTATYEFLYDNSTDPEQHTSGHINQDLTGKVTVK
                     KVGQHYLISQSGSKNITVVKEDNQLKAPSVFPESILGTWTGQANGLSIHMSLASDGTI
                     TTKVEDQKGNRSKETRTAKISKVEDKGNGFYLYTPDPGSDISALVPEGGLGGANVKYA
                     YGFKISGKTASPVVWQAALTHEFDYTKPLSGVTLQKQP"
     gene            complement(28328..29239)
                     /locus_tag="ACF4ZO_000502"
     CDS             complement(28328..29239)
                     /locus_tag="ACF4ZO_000502"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HFD5486074.1"
                     /translation="MKTTNKPSKGFTVTLKNPFEELTVKALLEEQLLIPRKIRHFLRT
                     KKHVLINGHPVNWQSCVKYGDQVKLFFDHEDYPEKIIVMGQAEKVTCLYEDEHIIIVN
                     KPEGMKTHGNDPTELALLNHVSAYTGQTCYVVHRLDKETSGAILFAKTPFILPILNRL
                     LEKRDIHREYLALVHGSLDSPRVTYHHPIGRHRHDRRKRVVDPINGKKAITEVTLVKN
                     FHKTASLLNCQLQTGRTHQIRVHLAHQGHVLFGDPLYSNGKKDCARLMLHAYQLRLKH
                     PLTQEDICVQAKSATFDAVLNAQKARK"
     gene            complement(29223..29414)
                     /locus_tag="ACF4ZO_000503"
     CDS             complement(29223..29414)
                     /locus_tag="ACF4ZO_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486075.1"
                     /translation="MNKFQAFKETLSAESLKAIYDETRLEVANDEREGTEAFSAALAT
                     QMAINLVEKYHNWLNEDNK"
     gene            29905..30285
                     /locus_tag="ACF4ZO_000504"
     CDS             29905..30285
                     /locus_tag="ACF4ZO_000504"
                     /EC_number="3.5.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HFD5486076.1"
                     /translation="MKTIRRYDVNEDRGHTGLVEAGDFYYLNYCVGNVGQDIESQING
                     AFDEMERRLALVGLTLDAVVQMDCLFRDVWNIPVMEKMIKERFNGRYPARKSIQTEFA
                     HHGGPQGLLFQVDGVAYSKHISMT"
     gene            30324..32660
                     /gene="pbp2a"
                     /locus_tag="ACF4ZO_000505"
     CDS             30324..32660
                     /gene="pbp2a"
                     /locus_tag="ACF4ZO_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein PBP2A"
                     /protein_id="HFD5486077.1"
                     /translation="MRFLELLQKKFFPKAYQEKQFLMHQKVRLTPQHNQKQYSPNANH
                     LDSSATKNSEQDPAIALQRSRAYEGSPKSRPAWLQKLEAVLPSPQHPIRRFWRRYHIG
                     KLLMILIGTLVLLLGSYLFYLSKTAKVSDLQDALKATTVIYDHKGEYAGSLSGQKGSY
                     VELNAISDDLENAVIATEDRTFYSNSGINLKRFLLAVVTAGRFGGGSTITQQLAKNAY
                     LSQDQTIKRKAREFFLALELTKKYSKKDILTMYLNNSYFGNGVWGVEDASQKYFGTTA
                     ANLTLDEAATLAGMLKGPEIYNPYHSLKNATHRRDTVLGAMVDAKKITQTKAQQARAV
                     GLKNRLADTYVGKTDDYKYPSYFDAVISEAIATYGLSEKDIVNNGYKVYTELDQNYQT
                     GMQTTFNNDELFPVSAYDGSSAQAASVALDPKTGGVRGLIGRVNSSENPTFRSFNYAT
                     QAKRSPASTIKPLVVYAPAVASGWSIEKELPNTVQDFDGYQPHNYGNYESEDVPMYQA
                     LANSYNIPAVSTLNDIGIDKAFTYGKTFGLDMSSAKKELGVALGGNVTTNPLEMAQAY
                     AAFANNGVIHPAHLINRIENARGEVLKTFTDKAKRVVSQSVADKMTAMMLGTFSNGTA
                     VNANVYGYTLAGKTGTTETNFNPDLAGDQWVIGYTPDVVISQWVGFNQTDENHYLTDS
                     SAGTASAIFSTQASYILPYTKGSQFHVDNAYAQNGISAVYGVNETGNQSGVDTQSIID
                     GLRKSAQEASQSLSKAVDQSGLRDKAQSIWKEIVDYFR"
     gene            32709..32861
                     /gene="rpmG"
                     /locus_tag="ACF4ZO_000506"
     CDS             32709..32861
                     /gene="rpmG"
                     /locus_tag="ACF4ZO_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HFD5486078.1"
                     /translation="MAQKKASLACVECGSRNYSIGVSSTPKPTRLEVNKFCKYCKTYT
                     LHKETR"
     gene            32875..33051
                     /gene="secE"
                     /locus_tag="ACF4ZO_000507"
     CDS             32875..33051
                     /gene="secE"
                     /locus_tag="ACF4ZO_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HFD5486079.1"
                     /translation="MGFISGTFKVLKDTTWPNRKQRWKDFISVLEYTAFFTVIIYIFD
                     QLLAKSVLALINLF"
     gene            complement(33288..34061)
                     /locus_tag="ACF4ZO_000508"
     CDS             complement(33288..34061)
                     /locus_tag="ACF4ZO_000508"
                     /EC_number="1.97.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0043687 - post-translational protein
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HFD5486080.1"
                     /translation="MTDRGIVFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCANPESQQ
                     KAPEQMLTSDGLNTKIVGEEKTVDEVIEEVLKDLDFYEESGGGMTLSGGEIFAQFDFA
                     LALLKAAKAAGLHTAIETTAFAKHEQFVTLIDYVDFIYTDLKHYNQLRHQKVTGVRND
                     LIIKNIHYAFQAGKEIVLRIPVIPQFNDSLDDAKAFSELFNQLEIDQVQLLPFHQFGE
                     NKYKLLGREYEMAEVKAYHPEDLADYQAVFLNHNIHCYF"
     gene            34187..34933
                     /locus_tag="ACF4ZO_000509"
     CDS             34187..34933
                     /locus_tag="ACF4ZO_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019317626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFD5486081.1"
                     /translation="MNRLERIIQLVSQKKKIDVNSLSEQLEVSKVTIRKDLDKLESKG
                     LLRREHGYAVLNSGDDLNVRLSYNYNIKRRIAEKAAELVQDNDTIMIESGSTCALLAE
                     VLCQNKRNIKVITNSCFIANYIRQYSSCQIILLGGYYQPNSEVTVGPLLKEMISLFHV
                     NRVFVGTDGFNKDLGFMGKDMMRSEGVRYMADAAEEVVILTDSSKFSKTSLVHQLSLA
                     DVNRVITDQALDKQTQELLSASGLVLDFVS"
     gene            34949..35929
                     /locus_tag="ACF4ZO_000510"
     CDS             34949..35929
                     /locus_tag="ACF4ZO_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HFD5486082.1"
                     /translation="MKEERRRLLAKVAYLHYIQGKSQTLISKEMNIYRTTVCRMLAKA
                     KEEGIVRIEIADYDADLFALEEYVRQQYGLEKIDLVPNQVEDTPMDTLTNVAKTAAEV
                     FRHVVKDGDKIGLSWGATLSCLMDELNPKAMKDVFIYPLAGGPSHINAKYHVNTLVYR
                     LARIFHGNSAFMNAMVIQEDKHLAKGILQSKYFNDILTSWDQLDLALVGIGGEPNSLE
                     QSQWRDLLTSSDHDQLKYEKAVGEVCCRFFDQAGQPVYTGLQDRTIGISLEQLRRVPK
                     TMAVATGKHKAKAILAALKAGFINYLVTDKETMLAVLALDEDIDLNNVLL"
     gene            36216..36536
                     /locus_tag="ACF4ZO_000511"
     CDS             36216..36536
                     /locus_tag="ACF4ZO_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HFD5486083.1"
                     /translation="MQVIVPDQIIMGLILNAGDAKQHIYQALKCAKEDDYATSEKEMA
                     LADDALLEAHNLQTQFLAQEASGNKSEITALFVHSQDHLMTTITEINLVKEIIDLRKE
                     LATK"
     gene            36564..36872
                     /locus_tag="ACF4ZO_000512"
     CDS             36564..36872
                     /locus_tag="ACF4ZO_000512"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFD5486084.1"
                     /translation="MIKIGLFCAAGFSTGMLVNNMKVAAEKKGIDCQIEAYAQGKLAD
                     YAPLLDVALLGPQVAYTLDKSEAICKDNDIPIAVIPMADYGMLDGNKVLDLALSLVKE
                     "
     gene            36882..38186
                     /locus_tag="ACF4ZO_000513"
     CDS             36882..38186
                     /locus_tag="ACF4ZO_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFD5486085.1"
                     /translation="MAKMNMQNIIMPIMTFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     AGQIPFQGVNDAIASVFGADWTEPFMQVYHGTFAIMGLISCFAIGYSYAKNSGVEPLP
                     SGVLSLSAFFILLRSSYVPAEGEAIGDAISKVWFGGQGIIGAIVIGLTVGAVYTTFIR
                     RHIVIKMPDQVPQAIAKQFEAMIPAFVIFTLSMLVYIIAKSVTGGGTFIEMIYDVIQV
                     PLQGLTGSLYGALGIAFFISFLWWFGVHGQSVVNGIVTALLLSNLDANKALMAAGELS
                     LDKGAHIVTQQFLDSFLILSGSGITFGLVVAMIFAAKSKQYKALGKVAAFPALFNVNE
                     PVVFGFPIVMNPVMFLPFILVPVLAALTVYGAIAIGFMQPFAGVTLPWSTPAIISGFM
                     VGGWQGAIVQILILIMSTLVYFPFFKIQDNMAYQNEQASEES"
     gene            38397..40814
                     /locus_tag="ACF4ZO_000514"
     CDS             38397..40814
                     /locus_tag="ACF4ZO_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HFD5486086.1"
                     /translation="MTETKIPYFGHLTDRMTHYREAVLDKKPYIDAERAILATEAYQK
                     HQNKPANLKRAYMLQTILENMTIYIEDESLIAGNQASSNKDAPIFPEYTLEFVLNELD
                     LFEKRDGDVFYITEETKQQLRDIAPFWENNNLRARCGVLLPEEVQVYMETGFFGMEGK
                     MNSGDAHLAVNYQKLLEHGLKGFEERARAAKAALDLTIPENIDKYHFYDSVFIVIDAV
                     KTYAKRYAKLARELAETASPERQAELLDIACICDKVPYEPAATFAEAVQSVWFIQCIL
                     QIESNGHSLSYGRFDQYMYPYVKADLEAGRETEDTIVERLTNLWIKTLTINKVRSQAH
                     TFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLRSVAQTKLPQPNLTVRYHKGLDNT
                     FMNECIEVMKLGFGMPAMNNDEIIIPSFIKKGVSEEDAYDYSAIGCVETAVPGKWGYR
                     CTGMSYINFPKILLITMNDGIDPASGKRFAKGHGHFKDMTSYEELKAAWDATLREITR
                     MSVIVENAIDLGLEREVPDILCSALTDDCIGRGKTLKEGGAVYDYISGLQVGIANLSD
                     SLAALKKLVFEEGQLTPEELWHALESDFAGERGEEIRQMLINDAPKYGNDDDYADSLV
                     VEAYDTYIDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGKGTLATPDGRHAGTPL
                     AEGCSPEHSMDKKGPTSVLKSVAKLPTDEIVGGVLLNQKVNPQTLAKEEDKLKLMALL
                     RTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSKATQDDII
                     ERTEHTL"
     gene            40827..41495
                     /locus_tag="ACF4ZO_000515"
     CDS             40827..41495
                     /locus_tag="ACF4ZO_000515"
                     /EC_number="4.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HFD5486087.1"
                     /translation="MEYMLDTLDLEAIKKWHHILPLAGVTSNPSIAKKEGEIDFFERI
                     REVRAIIGDKASIHVQVIAQDYEGILKDAAEIRRQCGDSVYVKVPVTTEGLAAIKTLK
                     AEGYHITATAIYTTFQGLLAIEAGADYLAPYYNRMENLNIDPEAVIGQLAEAINRENA
                     NSKILAASFKNVAQVNKSFALGAQAITAGPDVFEAGFAMPSIQKAVDDFGKDWEAIHH
                     RKSI"
     gene            41552..42640
                     /locus_tag="ACF4ZO_000516"
     CDS             41552..42640
                     /locus_tag="ACF4ZO_000516"
                     /EC_number="1.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0008888 - glycerol dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_function: GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HFD5486088.1"
                     /translation="MKVFASPSRYIQGKNALFTNAKTLKQLGDSPILLCDDVVYGIVG
                     ERFESYLIDNGMTPVHVAFNGEASDNEISRVVAIAKENGNDVIIGLGGGKTIDSAKAI
                     ADLLAVPVIIAPTIASTDAPTSALSVIYTDEGAFEKYIFYSKNPDLVLVDTQVICQAP
                     KRLLASGIADGLATWVEARAVMQKNGDTMAGGNQTLAGVAIAKACEQTLFADGLKAMA
                     SCDRQVVTPALENVIEANTLLSGLGFESAGLAAAHAIHNGFTALTGAIHHLTHGEKVA
                     YGTLTQLFLENRSREEIDRYIDFYQAIGMPTTLKEMHLDTATQEDFLKIGRQATMAGE
                     TIHQMPFVISPEDVAAALVAVDAYVTSR"
     gene            complement(42722..43231)
                     /locus_tag="ACF4ZO_000517"
     CDS             complement(42722..43231)
                     /locus_tag="ACF4ZO_000517"
                     /EC_number="3.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008962 - phosphatidylglycerophosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0006629 - lipid metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HFD5486089.1"
                     /translation="MSTDHHLREVSYQLLAERGVSLEAIAELVLFLQNDYIPNLTMAE
                     CLESVEAVLAKREVQNAIITGVELDKLAEANQLSEPLLSILKTDQGLYGIDEILALSI
                     VNLYGSIGFTNYGYLDKTKPGIVDKLNHKDGNSCHTFLDDIVSAIAAAAASRIAHNDP
                     AKSAITNQQ"
     gene            43595..44410
                     /gene="sdaB"
                     /locus_tag="ACF4ZO_000518"
     CDS             43595..44410
                     /gene="sdaB"
                     /locus_tag="ACF4ZO_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptodornase B"
                     /protein_id="HFD5486090.1"
                     /translation="MNLLGSRRVFSKKCRLVKFSMVALVSATMAVTTVTLENTALARQ
                     TQVSNDVVLNDGASKYLNEALAWTFNDSPNYYKTLGTSQITPALFPKAGDILYSKLDE
                     LGRTRTARGTLTYANVEGSYGVRQSFGKNQNPAGWTGNPNHVKYKIEWLNGLSYVGDF
                     WNRSHLIADSLGGDALRVNAVTGTRTQNVGGRDQKGGMRYTEQRAQEWLEANRDGYLY
                     YEAAPIYNADELIPRAVVVSMQSSDNTINEKVLVYNTANGYTINYHNGTPTQK"
     gene            complement(44651..45493)
                     /gene="ropB"
                     /locus_tag="ACF4ZO_000519"
                     /gene_synonym="rgg1"
     CDS             complement(44651..45493)
                     /gene="ropB"
                     /locus_tag="ACF4ZO_000519"
                     /gene_synonym="rgg1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982409.1"
                     /note="RopB (Regulator of Protease B) is a paralog of the
                     quorum-sensing transcriptional regulators Rgg2 and Rgg3,
                     which bind short, hydrophobic peptides encoded by genes in
                     their respective vicinities. RopB binds the leaderless
                     short peptide SIP (SpeB-inducing peptide), with sequence
                     MWLLLLFL; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     RopB/Rgg1"
                     /protein_id="HFD5486091.1"
                     /translation="MEIGETVEFIRHSKNISIKQVCGDYLTRQTYYRFIKNNLDISSK
                     KLLYILDNLNVNVDEFLFISNNFKQYKEFIDMDTAKHYFECRNIEGLNHILDSYKDSK
                     STKEKNLFALVKVLLATLTEEDCLTERTYLSNYLINIETWSHYETVLFNNCMFIFESC
                     FIEMVFSKVILNLDKYNTLRYYGNESIRMFVNMLILFIQRQEYDKASEILAKIEDYQL
                     NDDCLYERCCVSFFDGIIGLINGKEGAEQKCVQILEIFQLLNCKTIHHMFQTYLEAIK
                     HKLS"
     gene            45992..46162
                     /locus_tag="ACF4ZO_000520"
     CDS             45992..46162
                     /locus_tag="ACF4ZO_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486092.1"
                     /translation="MDNPKKDKGLSLGVVDPITILITESVINKMRTVPYHLKKLSSTT
                     YCLLADLAYQSA"
     gene            46433..47629
                     /gene="speB"
                     /locus_tag="ACF4ZO_000521"
     CDS             46433..47629
                     /gene="speB"
                     /locus_tag="ACF4ZO_000521"
                     /EC_number="3.4.22.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine proteinase exotoxin SpeB"
                     /protein_id="HFD5486093.1"
                     /translation="MNKKKLGIRLLSLLALGGFVLANPVFADQNFARNEKEAKDSAIT
                     FIQKSAAIKAGARSAEDIKLDKVNLGGELSGSNMYVYNISTGGFVIVSGDKRSPEILG
                     YSTSGSFDANGKENIASFMESYVEQIKENKKLDTTYAGTAEIKQPVVKSLLDSKGIHY
                     NQGNPYNLLTPVIEKVKPGEQSFVGQHAATGCVATATAQIMKYHNYPNKGLKDYTYTL
                     SSNNPYFNHPKNLFAAISTRQYNWNNILPTYSGRESNVQKMAISELMADVGISVDMDY
                     GPSSGSAGSSRVQRALKENFGYNQSVHQINRSDFSKQDWEAQIDKELSQNQPVYYQGV
                     GKVGGHAFVIDGADGRNFYHVNWGWGGVSDGFFRLDALNPSALGTGGGAGGFNGYQSA
                     VVGIKP"
     gene            47631..47936
                     /locus_tag="ACF4ZO_000522"
     CDS             47631..47936
                     /locus_tag="ACF4ZO_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spi family protease inhibitor"
                     /protein_id="HFD5486094.1"
                     /translation="MEMHFVRTEPEARRIAETFCAENTQTKTPMRVQQLSYPSDTDHS
                     GGELYIYALSPAGFIIVSGDTRAHTILGYSFDNNLDLNHDNVRSMIEAYQKQINSLD"
     gene            48416..49345
                     /gene="prsA"
                     /locus_tag="ACF4ZO_000523"
     CDS             48416..49345
                     /gene="prsA"
                     /locus_tag="ACF4ZO_000523"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HFD5486095.1"
                     /translation="MKQMNKLITGVVTLATVVTLSACQSSHNNTKLVSMKGDTITVSD
                     FYNETKNTELAQKAMLSLVISRVFETQYANKVSDKEVEKAYKQTADQYGTSFKTVLAQ
                     SGLTPETYKKQIRLTKLVEYAVKEQAKNETISKKDYRQAYDAYTPTMTAEIMQFEKEE
                     DAKAALEAVKAEGADFAAIAKEKTIAADKKTTYTFDSGETTLPAEVVRAASGLKEGNR
                     SEIITALDPAISKRTYHIIKVTKKATKKADWKAYQKRLKDIIVTGKLKDPDFQNKVIA
                     KALDKANVKIKDKAFANILAQFAKPNQKQPAQK"
     gene            complement(49618..49854)
                     /locus_tag="ACF4ZO_000524"
     CDS             complement(49618..49854)
                     /locus_tag="ACF4ZO_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486096.1"
                     /translation="MTHRFFLTPLSTLWRRLRPKRYSKKVLADEPTSYQPPAAHSPCD
                     DTHQLLEDKSLSDDYLIATSAMRHLWYWGYSQIG"
     gene            50098..50394
                     /locus_tag="ACF4ZO_000525"
     CDS             50098..50394
                     /locus_tag="ACF4ZO_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4298 domain-containing protein"
                     /protein_id="HFD5486097.1"
                     /translation="MTKQDQLIVEKMEQTYEAFSPKLANLIEALDAFKEHYEEYATLR
                     NFYSSDEWFRLANQPWDDIPCGVLSEDLLFDMIGDHNQLLADILDLAPIMYKHM"
     gene            50542..50826
                     /locus_tag="ACF4ZO_000526"
     CDS             50542..50826
                     /locus_tag="ACF4ZO_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HFD5486098.1"
                     /translation="MKFKKVLVIPALALAATCFLTACGTKKDSKKEEVKEIKMSDIKD
                     DAVSKKTKVVDGEEVTEYTTKDGNVIQIPAGNEEGMESKDAGGSGAPAKN"
     gene            51250..52518
                     /locus_tag="ACF4ZO_000527"
     CDS             51250..52518
                     /locus_tag="ACF4ZO_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_function: GO:0042802 - identical protein binding
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HFD5486099.1"
                     /translation="MFQLRKKMTRKQLALLSAGVLTCVVGGTYLIMNHQQQEIVSSVN
                     KVKALTIKEAMEQGKDISLTLAGEVTANNSSKVKIDSSKGEVKDVFVKKGDVVKVGQP
                     LFSYETSQRLTAQSSEFDVQTKANQLQVAKTNAALKWETYNRKVNEINTLKSHYNSAP
                     DESLLEQIRSAEDSVSQALSDAKTADSDVKAAQIELDKANATAATEKGKLEYDTVKSD
                     TAGTIVSLNTDLPNQSKSKKENETFMEIIDKSKMLVKGNISEFDRDKLKIGQKVEVID
                     RKDNSKKWTGKVTQVGNLKAEEKGQGQGQGGNDQQDNPNQAKFPYVIELDQSDKQPLI
                     GSHTYVNVLNNVPEAGKIVLKETFTMAENGKTYVWKVDKNKVKKQEIKTKPFSKGYIE
                     VTSGLTMQDKIAQPLPGMKDGMEVGSIVKP"
     gene            52505..53179
                     /locus_tag="ACF4ZO_000528"
     CDS             52505..53179
                     /locus_tag="ACF4ZO_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD5486100.1"
                     /translation="MLNLKDIRKSYHLGTEEFAILKGIDLEVNEGDFLAIMGPSGSGK
                     STLMNIIGCLDKPGSGSYAIEGRDVSSLSDNELADLRNQKIGFVFQNFNLMPKLTACQ
                     NVELPLTYMNVPKKERRKRALEMLKLVGLEERSEFKPMELSGGQKQRVAIARALVTNP
                     SFILGDEPTGALDTKTSVQIMDLFKQFNDNGKTIIIITHEPEVAALCKKTVILRDGNI
                     EHSDIE"
     gene            53192..54409
                     /locus_tag="ACF4ZO_000529"
     CDS             53192..54409
                     /locus_tag="ACF4ZO_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD5486101.1"
                     /translation="MEDIIAALGSILSHKMRSILTMLGIIIGIGAIIAIFSIIEGNTE
                     NTKRQLIGGSNNTINIVFNKKSSIDPKFPDKSNAKKPDYLPFMAEEELSKIQQVKGVK
                     NALISYGIDDKVYHLGQKSSAKISAITKNVAEVRRMTFIKGSDFSDKDFIDQKQVIYL
                     EKSLYESLFPKDDGLGKFVEVMGNPFRVIGVFESKEQSGLTSGTEKIAYIPLHQWYNI
                     NGVVDATPEITIQTYRADDLKPVAKRVSDMLNQTIPKSDYMFGVMNLKEFERQLDNLN
                     KSNFVLLAGIASISLIVGGIGVMNIMLVSVTERTREIGIKKALGARRKLILKQFLIEA
                     VILTLLGGVIGVISGMVSGLIITRSLEYPYILSLFSVVLSLAFCCIIGIVFGLLPAIK
                     ASKLDPIEALRFE"
     gene            54503..55156
                     /locus_tag="ACF4ZO_000530"
     CDS             54503..55156
                     /locus_tag="ACF4ZO_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFD5486102.1"
                     /translation="MFKILVVEDDDTISQVICEFLKANNYDPDCVFDGQAALDKWQTT
                     SYDLIILDIMLPSLSGLEVLKTIRKTSDVPIIMLTALDDEYTQLVSFNHLISDYVTKP
                     FSPLILIKRIENVLRVSTPDEKRQIGDLLVDETEHSVYWQGTLVKLTKKEYDIIDYLA
                     KRHQKIVTRDQLMDDIWGYSELDTRVLDNHIKNLRKKMTGIPLKTITGMGYLLGERE"
     gene            55153..56541
                     /locus_tag="ACF4ZO_000531"
     CDS             55153..56541
                     /locus_tag="ACF4ZO_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFD5486103.1"
                     /translation="MRLIKKTFLVINGLIIVVVTSILLVLYFAMPIYYTKVKDKEVKR
                     EFDQTSKQIKGKTVTEIRDILTKKINKDNIWYSLVDSDNQLLYPSLQLLDGVSESKDS
                     QNVNIVTTFDNSYSNVKVMSQKVTLRDGKKMTLLGQSSLQPVTDASKVLLDLYPSLLI
                     FSVTVGSIVAYLYSRTSSRRILSMSQTAKKMVNLEPNLTCTIHGKDEIAMLASDINRL
                     YASLSTSIKSLQKEYEKASDSEREKSEFLRMTSHELKTPITSVIGMIDGMLYNVGDFA
                     DRDKYLRKCRDVLEGQAQLVQSILSLSKIETLASQNQELFSLKSSLEEEMEVFLVLSE
                     LKHLKVTINLEEQFVKANKVYLLKAIKNIIDNAFHYTKSGGQVMIQLKDNQLVIKNEA
                     ETLLTQQQMKQLFQPFYRPDYSRNRKDGGTGLGLFITHQILDQHHLAYRFVVLDQRWM
                     VFTIDFPSHHDD"
     gene            56643..58247
                     /locus_tag="ACF4ZO_000532"
     CDS             56643..58247
                     /locus_tag="ACF4ZO_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HFD5486104.1"
                     /translation="MKKRKLLAVTLLSTILLNSAAPLVVADTSLRNNTSSTDQPTTAD
                     TDTDDESETAKKDKKSKETASQHDTQKDHKPSYNHPTPPSNDTKQTDQASSEATDKPN
                     KDKNDTKQPDSSDQSTPSPKDQSSQKESQNKDGRPTPSPDQQKDQTPDKTPEKGPEKA
                     AEKTPEPNRDAPKPIQPPLGAAAPVFAPWRESDKDLSKLKPSSRSSAAYVRHWTGDSA
                     YTHNLLSRRYGITAEQLDGFLNSLGIHYDKERLNGKRLLEWEKLTGLDVRAIVAIAMA
                     ESSLGTQGVAKEKGSNMFGYGAFDFNPNNAKKYSDEVAIRHMVEDTIIANKNQTFERQ
                     DLKAKKWSLGQLDTLIDGGVYFTDTSGSGQRRADIMTKLDQWIDDHGNTPDIPEHLKI
                     TSGTQFSEVPVGYKRSQPQNVLTYKSETYSFGQCTWYAYNRVKELGYQVDRYMGNGGD
                     WQRKPGFVTTHKPKVGYVVSFAPGQAGADATYGHVAVVEQIKEDGSILISESNVMGLG
                     TISYRTFTAEQASLLTYVVGDKLPRP"
     gene            58324..58575
                     /locus_tag="ACF4ZO_000533"
     CDS             58324..58575
                     /locus_tag="ACF4ZO_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486105.1"
                     /translation="MIKRVTTPSQKTKKRVRNGYLLKLGTACLLLSILSYAIGLLGQP
                     SMENTFMGIANVAMLGSVCFFIIFALNRIFDALEDNLRD"
     gene            59244..60836
                     /gene="mga"
                     /locus_tag="ACF4ZO_000534"
     CDS             59244..60836
                     /gene="mga"
                     /locus_tag="ACF4ZO_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence factor transcriptional regulator Mga"
                     /protein_id="HFD5486106.1"
                     /translation="MYVSKLFTSQQWRELKLISYVTENADAIGVKDKELSKALNISML
                     TLQTCLTNMQFMKEVGGITYKNGYITIWYHQHCGLQEVYQKALRHSQSFKLLETLFFR
                     DFNSLEELAEELFVSLSTLKRLIKKTNAYLTHTFGITILTSPVQVSGDEHQIRLFYLK
                     YFSEAYKISEWPFGEILNLKNCERLLSLMIKEVDVRVNFTLFQHLKILSSVNLIRYYK
                     GYSAVYDNKKTSHRFSQLIQSSLETQDLSRLFYLKFGLYLDETTIAEMFSNHVNDQLE
                     IGYAFDSIKQDSPTGCRKVTNWIHLLDELEINLNLSVTNKYEVAVILHNTTVLKEEDI
                     TANYLFFDYKKSYLNFYKQEHPHLYKAFVAGVEKLMRSEKEPISTELTNQLIYAFFIT
                     WENSFLKVNQKDEKIRLLVIERSFNSVGNFLKKYIGEFFSITNFNELDALTIDLEEIE
                     KQYDVIVTDVMVGKSDELEIFFFYKMIPEAIIDKLNVFLNISFADSLPLDKPIKNPLD
                     FHRKELTLPTPPNKLHAPPSTT"
     gene            61020..62291
                     /gene="emm"
                     /locus_tag="ACF4ZO_000535"
     CDS             61020..62291
                     /gene="emm"
                     /locus_tag="ACF4ZO_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein"
                     /protein_id="HFD5486107.1"
                     /translation="MAKNNTNRHYSLRKLKKGTASVAVALSVIGAGLVVNTNEVSARV
                     FPRGTVEDPDKARELLNKYDVENSMLQANNDKLTDQNKNLTDQNKELKAEENRLTTEN
                     KGLTKKLSEAEEEAANKEQESKETIGTLKKILDETVKDKIAKEQESKETIGTLKKTLD
                     ETVKDKIAKEQESKETIGTLKKILDETVKDKIAREQKSKQDIGALKQELAKKDEGNKV
                     SEASRKGLRRDLDASREAKKQVEKDLANLTAELDKVKEEKQISDASRQGLRRDLDASR
                     EAKKQVEKALEEANSKLAALEKLNKELEESKKLTEKEKAELQAKLEAEAKALKEQLAK
                     QAEELAKLRAGKASDSQTPDAKPGNKVVPGKGQAPQAGTKPNQNKAPMKETKRQLPST
                     GETANPFFTAAALTVMATAGVAAVVKRKEEN"
     gene            62659..>63134
                     /locus_tag="ACF4ZO_000536"
     CDS             62659..>63134
                     /locus_tag="ACF4ZO_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021340616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C5"
                     /protein_id="HFD5486108.1"
                     /translation="MRKKQKLPFDKLAIALMSTSILLNAQSDIKANTVTEDTPATEQA
                     VETPQPTAVSEEAPSSKETKTPQTPDDAEETVADKANDLAPQAPAKTTDTPATSKATI
                     RDLNDPSQVKTLQEKAGKGAGTVVAVIDAGFDKNHEAWRLTDKTKARYQSKEDLEKA"
BASE COUNT        20090 a        12411 c        13111 g        17522 t
ORIGIN      
        1 tttgtttatt ggtaagtgtt aagacaagct tttgctcatt ttgggtgaca cttgccaaat
       61 cgttttattt aagatatagt gaacttgact aatttttgga ggcgttttca tgacgaaggg
      121 tattcgattt caattgcttg gcagtcccca catttttctt gatgacaaag aacaattttt
      181 tgcctttgcc aaagcaaatg ctctccttta ttacttagtg gttaatggat ctgttagccg
      241 cgaggtggcg gcgagtctac tttgggaaaa taagaacacg caaacagcga aaaagaattt
      301 acgaaacgct atctaccagg tcaataaagt cttgcaagct gatgtgatta tttgtcccaa
      361 tcgcaacctg ctggttttga ataaaacact tgatatcaaa acagatatta acctttttct
      421 ggctgatccg ctagctcact tagaactcta ccaaggggag tttttgcagg gcttttacct
      481 taaaagtggt gaggaatttg atctttgggt ttcaaaaatg cgtatgcagt atgaacaggt
      541 atacctaaaa gcgtgttacc aaaaaattga agaaaagctc tctttagatg ccattgaaga
      601 tgtcgaagaa catttaaaac agcttattga acgtgatgaa tttgaagaga aaaattatca
      661 gctcttgatg aggctttatc agcaggggaa ttgtcctggt aaggtcatcg aaacttatta
      721 tcagttggct aatgtgttgg ataaggagct agggattcag ccgagtttgc aaagccaaca
      781 gatttatcag gaagtggtcg ctaaagatcg taatgaacgc aaaatcaagt attttttgcg
      841 caacagtaat cattttttgg ggcggattga tgagattaag cagctggaaa actattttgc
      901 caactgtttg gcctgccaag aggtaggagc tctgctctta attggtgata cagggattgg
      961 gaaacgaacc ctagccagac aggtcttagc caatcaaacc caaacgtttc aaattgtcac
     1021 agctaaatgt tttcgtgaag aggctatgga ttccttattg ccttggcgta atatcttaga
     1081 tggcctggga gatttggtga ttcaaaaccg cttattgacc accaaagctt ggaaggctgc
     1141 tcttaaacgc tgttttcctg cggcaaccat ttttcaagaa gataacaacc aaccctttat
     1201 caaggaccac accagcttgt tggtttcctt tattgttgat attttacaac atttggcaga
     1261 aatcaaggcg ctggtaatcc ttattgagga ttgtcattgg atggatgagg acagtttgac
     1321 cttgttgcaa cgggtcatga atcaattggt ccactatccg attgcttttg tcttgaccaa
     1381 gcatctagga acgactcctg agctcggtct ttgtttgaat gctttgatga gtcaggggcg
     1441 tttagaaagc atttgtttgg agccttttaa tcggcaagaa agtttggctt atattagcag
     1501 tcaattgggt agtcagccag tgacggaaga agaaatggag cacctctatc aagccagcca
     1561 aggcaaccct ttctttttgt cagaatacac tcaggcccta ctgcgtcacg aaaaatttgt
     1621 gcctttaacg cctgccatta aggctaagtt gggtcttaaa ctagctaatc taagtagtcg
     1681 tgatgacgca ttgttaaact atttgtcttg ttgtcggagg cctatccctc taaataccct
     1741 cgctcaattg atgttactgc ctttagaaga agtgatcgag atggtggata atctggggca
     1801 ctactatatt ttggtagaag aaagcgtagg agaggaggtg ttgatttcat ttcgtcagcg
     1861 gattattcaa ctctatagtt atgaccgttt atctttgtca aaaaggcgtt tattgcacgg
     1921 acaaattgcc aaacggttag aagatttact gcctattttg acaccaagcc ctcacttatt
     1981 agatgacatt gcttaccatt atcaggaatc acggcaggtg attaaggcct tggaatacaa
     2041 ccttaactat ctagatgcta ccttgccatt tcagcatgag ctgtttccta tttattcaaa
     2101 gagtattggc tccttggaaa agtcagatcg tgaccatcaa cgcttaatgg aagagcagtt
     2161 tgataagatt cggcaaagca ttgcggattt ggaactgacc tatgataata accgtgattt
     2221 ccagcagttg cttattcgtt tttcttacct tgaaggccgt tatgatattc gaacagggag
     2281 gtatcaagaa gggattaaac atattcaaaa ggtcatcgct ttggcaaccg agctaaaaca
     2341 gccctccttc ttgctagaag gctatcgcca gttaattcat tactgtatcc aagtggaaaa
     2401 caagccagaa atgcgttatt acactagtct ttcattggag gcagcggttg ctgctaatca
     2461 ttttgaggcc attgcgatta gtttgcggtt aaacggtctc tatcatttga ttattgggga
     2521 gttaaatgag gcagagcgtc tgcttcaaca gtcgattgac ttctttaagg tgacgccagg
     2581 cttgcaagct aactatgcga ctcagattgc tgctgcctta gattatttgg gggagattgc
     2641 ccagattcgc tatcagtttg aaaaggccgt tgcttaccaa aaacaagcca ttgccttgac
     2701 cgaaaacaag ccagctgagt tatcggtgag tattttttac attggattag ggatttccta
     2761 cttttattta gctgattttg aacaagctga gcaaatcttg agtttggcta aggaagcttt
     2821 ggtcaatcat agttatcctt ggaaagaaac gcaacttgaa atttacctgg ccatgattca
     2881 atggaaaaag ggcaattatc agccagcctt gaccctactt gattacagag aaaccttgat
     2941 gtctaggtat cgcaatccgc gtgataaggg cttggttttc tatttgatgg ctgtggtcaa
     3001 gtaccaattg atatttcaag gagctaccct aagtcagcag gaaaaagaaa tggcagacca
     3061 cctgttgtca gaatcctttg agtattatta tgagattgct agtactaacc tcaaccctta
     3121 tcgagattgt catttggtta gtgaactaga tggtctgcgc cagcaattct cctctaacaa
     3181 ctaagaccaa agcgaaaccc tctgaagtga atcagagggt tttatctatg ttgcgaatca
     3241 gagggtttta gctatgttgt gccataatct gtacgaggta aaagataaag gtggctgcta
     3301 aattggcggt gtggttatca atatcgtgcg gtggtgaaac ctcaaccaca tcaaagccaa
     3361 ctaattttcc gctagctgca atgtgttgca aaaccaagac ggcaagattt gggtcaacac
     3421 cgagggactg gatagcacta acccctggcg cagcaccaac tgagaaacaa tccatgtcga
     3481 tagtcaggta gaccctttct tgcccttcta agaaacggtc aatggctcgg cagatctttt
     3541 gatggcccat ttggtagatg tcttgacctg ttaaaaattg aatgcccttg gattttgcca
     3601 caaagtcaaa taggaaaagg ttgttattat gttcttgaat gcctaaaacg aagtatttaa
     3661 agaggcgttt gtcagcaacc gcatcgtcaa acatttgtcg aaagcctgtc cctgaattag
     3721 ggcctgtttg gtcgtaaggc cttaaatcaa agtgggcgtc catattgatg acagctaggt
     3781 catcacttgg ggataggctt tggcgtaggc ctaagtagtg gccgtaggcg gtttcatggc
     3841 cacctcctaa gacgatgggt ttgagattga ggtcacacat ccgtttgatg gctttgctta
     3901 aactgttttg cagttgttcc aaagagcgat tggggccgtc aatgttaccc acatcgtaaa
     3961 ccataacttg gtttcctaaa tgccaaggga atttggcgag ctgggttcgt atagcagctg
     4021 gactttcgac cgctccgaca cgaccattat tgatataaac ccccttatca cttttaaagc
     4081 caatcaaggc aaaatgtgtc ccttcaaatg gggttagtga gctgtcgtta aggtcaagga
     4141 aagtcatgac catgccccat ttggcagtat ataagtcatc gtcgatccca ccatgataat
     4201 agctagtggt ggatgggtag taatcttcta gcatgcgcgt catctccttt aggattatga
     4261 tagcaaaata aaacttacag tcaactctct ataggctgtc atcactggtt tttaggaata
     4321 gcagagcaat aaaatcgtct gcttttggtc ccagttagtt agtctaaaga ggccatgacc
     4381 tctgccacag cccctctagt taaagaagta ccttattcac taaaattgga tactcaactc
     4441 aactgcctgc tcaaccgctt cgaggaagct tgggtcttca atgactgctg atgccttgtt
     4501 tagttcatcg tagatttcga tgtgtttatc gtgttcgata aagttgactt ccttgcggaa
     4561 gagatcgtag gcaaccttag tccctttacc tagttcatga ttttcaggtt tgagatcaag
     4621 agcttggcag gctgccatga tttcagtagc cacgatgcgg cgagaatttt taaggatttc
     4681 aaaggccttg cgagcagcgg tggtgcccat gctgacaaaa tcttcttggt tttcacaaga
     4741 tgggatagaa tccacactgg ctggatgtgc caaaaccttg ttttcagaag caagagaggc
     4801 acaggcgtac tgggtaatca taaagcctga attgagacct gggtatttga caaggaagga
     4861 tggtagtttg ctgagctggc tattgaccaa acgttccaca cggcgttcag aaacatttcc
     4921 aatttcagaa atggcaatgc ctaagaagtc aaatggctgt gccattggtt ctccgtggaa
     4981 gttacctcct gaaataacgt ggccatcttt acagataatt ggattatctg tgacagaatt
     5041 gatttcaatg tcaactttgg atttgacata ggcgatactg tctttgctag ccccatgaat
     5101 ttgaggcagg cagcgcaagg tgtaagggtc ttgcacacga gattgagtag ccacggttgt
     5161 gttttggctg ccttcaagga ggtttcggat attgcgggct gttgccaact ggccgctttg
     5221 tgggcgaatg gtgtgaaggt tttcttcaaa tggactagtg attccgttat gcacttcaag
     5281 ggaaagggca ccagctaggt ctgacagttt caataattga atggcgtcat aggttgcaag
     5341 ggcaccgatt gcagtgagaa cagttgttcc gttgataagg gcgagtcctt ctttagcggc
     5401 taaagaaatc ttgtcaatac cagctttatc aagagcttct tgaccagaaa gaagctctcc
     5461 tttgtagtaa gctttcccta gaccaagcat aggaagcacc atgtgagcaa gcggtgccaa
     5521 atctcctgaa gcccctagag accctttttc aggaatgtaa ggatgaaccc ctttattgag
     5581 cagttccaac agtttttcaa tggtggatag acgaatacca gaataccctt tgacgagaga
     5641 gttgatacgg atcagcatga tagctctcac ggcatcttct ggcaatgggt caccaaatcc
     5701 actagcatgg gtacgaatca aattttcttg gagttggact gtatcttctg gtgagatgct
     5761 cacgttacaa agggatccaa aaccagtggt caccccgtaa accacccgtt tttcactgac
     5821 aatgtcatca acaattttac gagaggcatt cacagcttca atagcactat catcaatgcg
     5881 acaggctacg ccttggcgag caatcgcaat cacgtcttcg atagtaaggc tttcgccatc
     5941 taaattaatc actcttgtca tattttttct cctagatttg ttccttaggg ggcatttggt
     6001 ccatttggtg gctacgtccg tgcataaggt agtacacact acttgcaatg atgacaccaa
     6061 ctgcaccata aacaaagttc attgggttgt caccccaaat cataactaaa ctaacgataa
     6121 ctgcaagaat cgggataata gggccaaatg gtactcggaa gatcacatta gcatcaggag
     6181 catctttccg taatttcata acggctagtg ctgttggaat gtattggaag aagcggaaaa
     6241 caacactgag ttttgctaag ttttcaaatg agccagtgag taggagtaca atagcaattg
     6301 ctcctgaaac caagatagca acgagtggtg cgccattttg attttgcttg gcaatagcag
     6361 ctggtaagag cccttcatca gcaatggcag caccgtaacg tggcaccatg atggattctc
     6421 ccatgttaag acctgtaatg gaaattaaag caccaattga gaccatccaa gcgccagcag
     6481 ggcctatcat tttaacaaag gcatcttgaa caggtgcatt ggtcatcatg atttgagagc
     6541 caagcatggc aatggttcca ccgataatca gcatatataa gacagagacg atactgattg
     6601 atcctaaaag agcacgcggt acattttttt cagggtcacg catttcccca gcaacaatag
     6661 agagggtttc aaaaccgata aagccataga agatataaac agcagtattg gagatagccc
     6721 ctaagaggtt agtccctggt tccaactgaa caaatggggt aaagttagga agcccgtttt
     6781 tgatgaagaa aagggtacag gcacaaaagg caacgattgg aattaactta gcaatggtgg
     6841 ctgtgatggt gacaatttta gaggttttca aaccagcgat attcatcaaa gatagtaaga
     6901 tgattaaccc aatgctaagt ggaatgtgcc aaccttcaaa ggcagggaaa gtaatgataa
     6961 acattctggc aaacccagct gccatggctg cccaagcgaa gatggtaacg gtccaaccaa
     7021 ggaagccaac gttaaagcca ataaaatcac caaaagctcg tttggaatat tggaaggccc
     7081 cgccgttttt cccaaaataa ccagagactt ctgcaaaaca aactgccaac atgatggtca
     7141 aaatagctgt tccaaacata acagcgatgg atgcagggcc aaggcccttg taaatggccc
     7201 taggtaagag aaaaatacca gagccgataa cggcattgat cccgtaaaga gtggcaccgc
     7261 tcaagctaaa ctttgcctgt tctctttctt gttcgttcat gtgatttgac gccataataa
     7321 tgctctcctt tttgtttgca aattgcgttc aaatataatg gataaggtcg ctaggaaatg
     7381 aggagatagt cggtttagga ggatccttct tgcatctaac gatagtgatg agctattggt
     7441 tagcgatgag aaataggtag ccttttgtga tgatgtgtag tgatttcatt ggagaagaat
     7501 aggcatgagt agtgtgatgc ctatctttat cccactaagt cttataccat aagcctgccc
     7561 aaacagctac tggagtttgg gcggggcttg tttgattggg gcaaactttt aggtctgaaa
     7621 ggctggcctc ctgctcgatt accaacaagt gattggcttc aagctcttga ttcgcctgat
     7681 tggtcacaga ataagtcaat ttgcttaggg cataaagcag ttggcagtcc gctttgggtg
     7741 cctcaaatag tgtgtcagac cagacgggta ataattgccc ttggtaatga tcatcataca
     7801 ttaaattgat gtcttggcag gttccacgac tgacgattct ggtatcgcct tcaaacgcat
     7861 agggttcaaa aggagctagg gaaatctctt tagcatgact caaatcactt aatgtgatgg
     7921 gcttgtctag gctcattagg atcctgtgat agccatcaag tcgggtaaag gttgtctgtc
     7981 gtagggctac agttgcagtt gagagacgat aggagaacgt tctttctttg tagtctccct
     8041 tttcaggata aaggaacaat tggttggttt caccgccaga ccagtcagtt tgagtgtaat
     8101 ctgctggcgt tttgattgtt acggttgtca tctgttctct ccttgtttcc aattagaata
     8161 gtcctgtgat gttgccctcc tcgtcaatat caattgtttc gctggcaggt acttttggaa
     8221 ggccaggcat ggtcatgata gcacctgtca gggcaacgat aaatcctgct cctgcggaca
     8281 ctttaaggtt gctaatagtc actataaagt cagttggtgc gccaagtttt ttggcatcgt
     8341 ctgagaagga atactgggtt ttggccatgc aaattgggta gttgccaaag ccgaggcgtt
     8401 ctaattctgc cagttcacgt ttggctgtgg gggtcaattt gataccctta ccaccgtaaa
     8461 tcttggtaac gattttagtc agtttggttt caatgctatc gtcttcattg taaacaaagc
     8521 ggaattgatt gtcttgttct gccaatgcta ctactttttc agccagttca cggccaccag
     8581 ctccgccatt cgcccaaacg tcagaaatca caacatcaac gccacgtttg tcgcaggcat
     8641 catagacagc ttgtaattcg gcatcggtat caagcgggaa tttattgatc gccacgacaa
     8701 ctggaagacc atagacgtct tggatattag ccaaatgttt gtcaaggtta ggtaaaccat
     8761 ccacaacggc ctgaacattt tcagtagcca ggtctgcttt tggcacaccc ccatgcattt
     8821 taagggcacg aatagtggct actaggacaa cggctgctgg acgaaggcct gacatgcggc
     8881 atttgatgtc aatgaatttt tcagctccaa ggtcagcacc aaatccagct tcggtaacgg
     8941 cataatcgcc atatttcaag gctagtttgg tggctaggac actattacag ccatgggcga
     9001 tattagcaaa tgggccaccg tgaatgaggg ctggtgtgtg ttccagggtt tgcacgagat
     9061 taggatgaat cgcatccttg agcagtgctg ctagggcacc accagctttc aagtctttag
     9121 ctgttacagg ttcaccttgg aagttgtaac cgatgataat tttttcaagg cgggctttga
     9181 ggtcagaaat attttcggat aggcacagga ttgccatgat ttcagaggcg acggtaatgt
     9241 cataaccatc ttcacgaggg accccgttga ccttgccttg caagccgtca acaatatgac
     9301 gaagctggcg gtcattcata tccaccacac gtttccaagt gatacgtcta gaatcaatgc
     9361 ctaggctatt gccatggtga atgtggttat caatcaaggc agctaataag ttgttggcga
     9421 caccgatggc atgaaagtcc cctgtaaagt gaaggttgat gtcttccatt gggacaactt
     9481 gcgcgtggcc accgccagca gctcctccct taaccccaaa aacaggacca agagaaggtt
     9541 cacgaagggc aataactgct ttttttccaa tggcagaaag agcatctacc aatccaacag
     9601 aagtggtggt tttgccctca ccagctggtg ttggtgagat agcagtgaca agaatgagtt
     9661 tgccatcagg tttgtctttt aaggcgacca gttgacgggc atcaattttt gccttgtact
     9721 taccatagag acagagcgtt tccttgtcaa tccctaattg atcggcaacc ttactgatag
     9781 gttccatagt gacagagttg gctatttcaa tatctgataa aaccatagtt gctcctttac
     9841 ttgttaaaca atatcgagaa ttttcgtgta gatgtcatct gccaaatgac agcccttgtc
     9901 taataaggct tgtccttttt ggcgatagtc ggtaacaaag tcttcatctt tgatgccaga
     9961 cagattaatc aaaacattca accaagcgcc ttgtaaacct gcttttaagt ttaaagcagc
    10021 aactcctaag tcgctagcag catttgtatt agacttaccg acagctgttg cagtgatctc
    10081 aagtgcttcg accatgaggg tcatcatctc aaaaggtgat tgtgcagctg tttttaaagc
    10141 ctcttgcatg gcagttcgtc tggcagcctt gtcttcgtca gtctcttttg gcatgtcgaa
    10201 aacgtcagaa actaggttaa aagcttcggt gtctttgtca atggcatcta ataagtcctg
    10261 ttgcaagcga ctacttttgg tatgaaggtc ttcaatgata tcttgataat cagcatactt
    10321 tttcttacca agggtcaatt cacagaccat cttggtcaag gaaatgccat tagcacctga
    10381 tagtgcagca gcagaaccac cacctggagc aggggcatct gagccaagga ctttagcgaa
    10441 atctgttaag cttaaatcaa ctaaacccat agagaacctc ctaacctagc aaatggtttt
    10501 caagaatctg tttattatag tcaaagtcct caacttgcaa gtagtattca gccacatcga
    10561 ttaaggcctt ggctggcgct aagccgatga cttcagaacc aataacattc acaccgtagc
    10621 gacgcgcttc aaatttgatg gtttcaaaag tacggtaaag agaacatttt tcaaagttaa
    10681 ccatgttcat ggaaacttgg gcaatatgac ggtcttctaa catgacaccg atagccttac
    10741 aatatttgta gccaccacct gaaccgcgga taattttagc aattttatga gcaatgtcga
    10801 tattgtcagt atccaaatta acattgaaag caaccaatgg catgcgagca ccaacggcag
    10861 ttaccccagc agttgggtga atcttacgat ctccgtaatc aggtgcccaa tcctcttcca
    10921 acagtttttc tggcatgcct tcgaattgtc ctttacggac tttggccagg ttttgacgtt
    10981 ctggacgtgt ggcagaatct tcataaagga agattgggat tccaagttca cggttaatcc
    11041 gttctgcgac ttgtttggaa atttcgacac attcttgtgt agtgatgtct ttgatcggga
    11101 cgaacgggca gacatcggtt gctcccatac gagggtgttc accatgatgt ttggtcatat
    11161 caatgttttc agaagcgtat ttcaccagtt ggaaagctgc ttcttgaata gactggtcat
    11221 ctccaactaa ggtaaacacg ctccggttgt ggctcgcatc agaagagtag tcgaggaggg
    11281 tcactccagg aatacttttg gccgtcgcta ccaagccgtc gataacagcc tgattttggc
    11341 cttctgagaa gttgggaata cattcaacaa ttttcgccat gttaatctcc ttttatgtca
    11401 ttgagttact cattaaggga atgggttacc tattatagat aacgcttaca tttttatcta
    11461 gctgctttta ctgaaataat tgatttaccg ctgaagtcac aaggtcatcg tcagccaaat
    11521 atggaatagt gatgtgatca gtacctgcat ggagacgatt atactcaata gcggtttcaa
    11581 tagcgtgttc attgcgagcc caattgcgac gagcaacacc acccatggtg tcccaagcaa
    11641 tagcagattt aataatctca tcaatgcgtt cgctgccatc taaaacaagg ccgaaaccac
    11701 cattgatggc tttaccaata ccagttccgc caccgttatg aagagccact aaactcatac
    11761 cacgcgcagc gttaccagcg taacattgca ccgccatatc acaggtcaca ttggaaccgt
    11821 ctttaatgtt tgaggtttca cgaaatggtg agtcggtacc agacacgtca tggtggtcac
    11881 gaccaatcat gacaggacca atcttgcctt tgcggaccaa ttcattaaat ttaagggcga
    11941 tagtcacacg accgatacag tcttggtaaa ggatccgggc ttgggtacca actacgagtt
    12001 gatttttctc agcatcacga atccagttgt agttatcacg gtcttgatag cggcggtcag
    12061 gatcgatagc ttccatggca gctttgtcag tagccaccaa gtcttcgtgt ttaccactca
    12121 agcagaccca acggaaaggt ccatagccat agtcaaaaag cataggtccc atgatatctt
    12181 ccacatagga tggccagata aagccgtctt tgtcgttacg accattctta gaaatttctg
    12241 taataccaga gtcgtaaaca gacttcataa aggcattgcc gtagtcaaag aaataggtgc
    12301 cattttcagt taacgtctta atagcttcaa aatgccgtgc caaggtatca tcaaccattt
    12361 ggtggaaggt atccttgtct tctgtcagga gccgggttct ttcgtcaaag ctaataccta
    12421 ctgggcagta gccaccgtca taaacgttgt gacaagaggt ttggtcagac aaaagatcaa
    12481 catgaatctg cttgtcattg acgtactcta aaaggtcaac aatattacca tggtaagcaa
    12541 tcgaagtgga ctccttagca tctatggctt tttgggctaa ttgcagagct tcttcagggc
    12601 tttcggcaat ttgactgatc cagccttgag aatgacgggt ttcaatccga gattggtcaa
    12661 cttcagcaat aatggcaact gctttagcaa tttcagcagc cttaccttgt gccccactca
    12721 tgcctcctaa accagatgag ataaagagtt taccggtcaa atcaccatcg tcagccactc
    12781 caagtttgag acgaccagca tttaagagag tattaaatgt tccatgaaca atcccttgtg
    12841 ggccaatata catccaacca cctgcggtca tttgaccata gttggtgaca cccatctctt
    12901 cagcgatttc ccagtctttc atgttgtcgt attcaccaac caaaagtcca ttagtaataa
    12961 tcacacgagg ggcttcaggt ttggattgga aaagaccaac ggggtgaccg gattcaacca
    13021 ccaaggtttg ttcatcagtc atgacttcta ggtatttttt aatcaaacaa tattgcatcc
    13081 agttggcaca aacagaacca gtttctccat aagtgactag ttcgtaaggg tacaaggcaa
    13141 tttcaaaact caagttattg tcaatcatga cctgcatggc cttggcagct gtacaatttc
    13201 ccttgtactc gtcaatgggt ttgccgtaaa tgcggtcttt tggtctaaag cggtagccat
    13261 aaatacggcc acgggttttg agttcttcca aaaattctgg aatgacttct tcgtggaact
    13321 ttgtaggtac atagcgtagg gcatttttta aggcaatttc ggtttgggct tgggtcaatc
    13381 gaaaacctct gtctggtgct cttcggatac cttctttgaa gacagtcttt tccggtaaaa
    13441 catcgtctaa cttaacagtc atagcggcag ctatgtcagt ttcactgtaa aatgacatag
    13501 aaaactcctc ctcaactcct ttttattgtc gagattagtc taacttagtc tagtctataa
    13561 aaagtcaacc acgctttgaa atgcgaaaaa agtctaaaaa aaaatcaaaa cctcattttt
    13621 tgactaaaat ttgacgctta atcagtacac ttgaggtatg acagataaag tcagtcagag
    13681 gttaattgtt gttaccaaag ttgcagagat cgcaactatt gagtgggtga ggggggctag
    13741 taatggctat taatcagttg acaaacgatg ttaaaaaagg aggtttttat ggttgctgat
    13801 gtcttattaa cacattttaa tcaactattt tgtctaaatg atccaggtca tcctttaact
    13861 ggtcaagaaa tgaaaaaagc cactatcgtt gaagatggct atatagccat caaagacggc
    13921 ctcattgtgg ctcttggttc tggtgaacca gatgctgagc ttgtcggtcc acagactatt
    13981 atgcgttctt ataaaggtaa aattgcaacg cctggtatta ttgactgtca tacccatttg
    14041 gtctatggtg gcagtcggga acatgaattt gccaagaaat tagcaggggt tccttattta
    14101 gacattcttg ctcaaggtgg tggtatttta agcacggtga gggccactcg gtcagccagc
    14161 tttgacaacc tttatcaaaa atccaagaga ttgctagact acatgttgct tcatggagtg
    14221 actaccgtcg aagcgaaaag tggctacggc cttgattggg aaacagaaaa acgccaactg
    14281 gatgttgttg ctgctttaga aaaagaccat cctattgatt tggtgtctac gtttatggca
    14341 gcccatgcga ttcctgaaga atacaagggg aatcctaagg cttatctcga tgtgattatc
    14401 aaggatatgc ttcctgttgt taaagagaaa aatctggcag aattttgtga tattttctgt
    14461 gaaaaaaatg tttttacagc tgatgagtcc cgctatctgt taagcaaagc caaagaaatg
    14521 ggcttcaagc ttcgtattca cgcagatgaa attgcgtcta taggcggagt tgatgtcgca
    14581 gcagagctca gcgcagttag tgcagagcat ttgatgatga taacaaatga tggtatcgct
    14641 aagttgattg gtgctggtgt tattggtaat ttgcttccag ccaccacctt tagtttaatg
    14701 gaagacactt atgcccctgc tcgcaaaatg atcgatgccg gcatggccat caccctctca
    14761 acagatagta atccaggcag ttgcccgact gctaacatgc agtttgtgat gcaattaggt
    14821 tgttttatgt tacgtttaac accgattgaa gtcttaaatg ctgttaccat taatgcggcc
    14881 tactctgtca atcgtcagga gagagttggt agtttgacag ttggtaaaga agcagatatt
    14941 gccatttttg atgccccaaa tattgattac ctattttatt tctttgccac caacttgatt
    15001 caccaagtct ataaaaaagg acaactcacg gttgatcgag gtcgtattct ttaaaaaatt
    15061 tcaaaaagaa gctttgagcg ttagctcaaa acttctttta aatatgctgt tttattgacg
    15121 aatcaagtag tcaaaggcac cgatggcagc agtagcacca gaccccatgg aaataatgat
    15181 ttgtttataa gctgaatcag tacagtcccc agcagcaaag atgccgggaa tattggttga
    15241 accatgttta tccacaatga tttctccgcg gtcggttagg ttgacaccac tatctttgag
    15301 ccaagctgtg tttggaacaa gaccaatttg aacaaagacc ccttcaaggt caaggtgttt
    15361 gtcttcaccg ctatcacgtt cagtgtagtt gagaccagta acatgatcgt caccaacaat
    15421 gtctttagta gcaacatttt tgataatagt catgttagca gtatcagctg cgcggtcttg
    15481 aagcactttg tcagctttga gctcaggcaa gaattctaac acgtaaacgt gtttagcaag
    15541 accagccaag tcaagggccg cttctaaacc ggagttacca ccaccgataa cagcaacatc
    15601 tttgccttca aagagtgggc catcacaatg aggacagtaa gtcacccctt tattacggaa
    15661 ttcatcttca ccaggaacat taatgttacg ccatttggcc ccaagagcta agatagcagt
    15721 tttggcttgt aaaaccgcac cattagctag agtaacctcg atgttttctt ttttctcaat
    15781 agaagtagct agttgtgctt tgataatatc aacatcataa gacttagtat gggcctccac
    15841 ttcggccatt aattttggtc cttcagtgta aagggtacca atcatgtttt cgatgccgac
    15901 cgtttccatg acctgaccac caaaggtttc agcaagtaaa cctgttttta gtcctttacg
    15961 agctgcatag atagcagcgc tattgcccgc agggccacca ccaataacaa ggacatcata
    16021 gaggccttta tcagcaaagg cttcctcaga aagtgggcca gcgatttgtt ctaagagttg
    16081 ctcaatggta gcacgaccag aagtgaattc ttccccgtct aaaaagacag tagggacaga
    16141 cataatgcct ttggctttca cttcatcttg gaacatgccg ccttctacca tagtgtgtga
    16201 aatcttgtcg ttcaagacgg acataatgtt taaagcttga acaacatctg ggcagttatg
    16261 gcaggttaag ctgacataag tttcaaaatg caacggacgg tcaatggcct tgatgcgatc
    16321 aataacatct tgatccactt ttggagcacg tccagatact tgcaagagag caagaataaa
    16381 ggacgtcaat tcgtggccta aaggaagacc agcaaagaca accccactat cgtgaccttt
    16441 tttcgcaacc ttaaagcttg gttgtcggtc taaagtgatg ttttcaatag aaatacgctc
    16501 agacatagca gctatttctt ccacaaagtc tttgactttt tgagactgct cattgtcacc
    16561 aagggaaact tgcaaaacaa gatcagcttc taacagggtg aggtattggg caagttgttc
    16621 tttaatatca ggacttaatg ccatagcttt cctcctaaaa tttattaaat tttaccaact
    16681 aaatcaagac ttggtgtcaa tgtttcagcg ccttctttcc atttagctgg acaaacttca
    16741 cctggatgtt tacggacgta ttgggcagcg tgaattttat caatcaaggt gctagcgtca
    16801 cgtccaatac catcagcatt aatttccatc atttggataa tacaatctgg gtcaacgata
    16861 aatgttccac gttgagcaag tccgtcttcg ccaagcactt caaaggcttg tgaaataagg
    16921 tgtgaagggt caccaatcat agggtatgtg atagtgccaa ccacatctga atcatcatgc
    16981 caagctttat gaacaaaatg agtatcagta gagacagaat aaacttctac accaagagat
    17041 ttcagtgttt cgtattgctc ttgaaggtca ccgagttcag ttgggcaaac aaatgaaaag
    17101 tctgctgggt agaaacaaaa aactgcccat tttcctttga cgtcttcatt tgtaacagtg
    17161 atgaattttc catcatgata agcttgagct gaaaattcag caatttcttt tccaattaga
    17221 gacatatagt tgtcctcctt ttttatagtt ttatacttgt attataaaag aacaacaaga
    17281 ttatgtctac tcagaaaccc ttgattttac tgggaaatca gcgattgttt tctgacaatt
    17341 cagttgtgaa acaaatcaca ttaattaaaa tgattctaaa taagctgaag atgccgttaa
    17401 atcaaaggtt aatttaatta taatctacag aaaatataat tgttattaaa gcgtttacaa
    17461 aaaaactttt ttgattccgt taaggcaact taatattatg gttacctaat cactaatatt
    17521 gtaacctatt ttggcatgag atcagggaat ggctgttata ttaattggat atgtcttgtg
    17581 caaatagtgc ttgacggatt tgtggaatta gggtaaaata atctttgttg tggcggtata
    17641 gccaagtggt aaggcacggc tctgcaaaag cttgatcgtc ggttcaaatc cgtctaccgc
    17701 cttttatata caaaacaagc cttgattaac ttcgtgaaaa cgttgttaaa tcaaggtttt
    17761 tattttttgc gacaggataa aaaaagagaa aaaaagaaat aaagtcggtc aaatttcccg
    17821 aagatgtctt ttatagcctg attattaggt atgaaaaata ctatggccaa aattggtaaa
    17881 cgattgcaaa tgaaggtcag agttcttacc cccttaaacg atatgcgtta aaagttagtt
    17941 gaactgccgt gcaccttaac gatagacacg gtgatgtgag agcgagtaga gttgaatctc
    18001 tactcgctta tcttaccata gtcagcttta taaagtaacc acccattaca atgcaactat
    18061 attcttaatg tttttaagca tgttattgac aagtgttata aaatgtgtta ctcttagtga
    18121 gtaaattagt ttttgagtta gtatttgtgt ttcaacatct ttatttctct ctatttttac
    18181 aaatgatttt tagaaaggaa gtggatgtat atggcacaag gtacagtaaa atggtttaac
    18241 gctgaaaaag gttttggttt tatttcaact gaaaacggtc aagatgtctt tgcacatttt
    18301 tcagcaatcc aaactagtgg ttttaaaacg ttagaagaag gacaaaaagt ggcatttgac
    18361 gtcgaagaag gtcaacgtgg acctcaagca gtcaatatca ctaaattggc ctaatctggt
    18421 taaagtaact aaagagaagc agatgttgga aacaacaact gcttttttga tttctaccag
    18481 ttacctttaa tgattaagag ttgcgtttaa ggtcttgtat ttgttataat aatagtcagt
    18541 tttagtcaaa atgtattgac gtggtgctac taagttttta gagtagcccg caagcaaagg
    18601 agtgacagca tgccaaccaa aaatacttca gacagcattg aagagtatat taaagaatta
    18661 ttagctaagt caggaatagc agaaattaag cggtccatgc tagcagattc gtttcaagtt
    18721 gtcccaagtc agatcaacta tgtcattaaa acccgtttta cggagagtcg aggctatgaa
    18781 gtagagagta aacgaggtgg tggaggctat attcgtattg ccaaggttca tttttcagac
    18841 aaacaccatc tgattggcaa tttaatggca actattgaag actgtatcag tgagcaagtt
    18901 ttcacggact cgatacaatt gctttttgac gaacacttat tgacagagcg tgagggaaat
    18961 atcattttgg ctgtggcgtc tgatgatgtt ttaggaactg atggttcaac tattcgtgca
    19021 cgaatgctct atcgcttatt gcaacgaatt gacagaaagg gaagcaatta atgattatgt
    19081 attcaacgaa gatgcaagac atttttagac aggcgcagtt ccaagctgct cgctttgata
    19141 gccattgcct ggaaacttgg catgttttgt tagctatggt agctgtagat aattctttag
    19201 caaatatgat tttaagtgaa tatgatgccc aagtcgccat agaagaatat gaagctgcag
    19261 ctattttagc catgggcaaa acccctaagg aacagttgtc tcgtgtagac ttcagacctc
    19321 aatctaaaac cttgactaac ttgttagctt ttgcgcaggc tattagccaa atcactaggg
    19381 atcaagaagt cggctctgag catgtcttat ttgctatttt attgaatcca gatattatgg
    19441 cgagtcgttt gttagaaata gcaggctatc agataaaaga taacggcaat gggcagccgc
    19501 gattagctga cttgcgaaaa gcaatagaac gtcatgcagg ttacagtaag gaaatgatca
    19561 aggctattca cgaactacgt aagcctaaaa aaacgaaaac acaagggacc ttttcagata
    19621 tgatgaagcc accaagtaca gctggtgagt tgagtgattt cacaagagat ttgactgaaa
    19681 tggcaagaca aggtttgtta gaatcggtga ttggacgtga ccaagaagta tctcgtatga
    19741 ttcaggtact aagtcgtaaa acgaaaaaca atcctgtctt ggtaggtgat gcaggtgttg
    19801 gtaaaactgc gcttgcttat ggccttgctc aacggattgc aaatggcgct attccttatg
    19861 aacttaagga gatgcgtgtc ctagaattag acatgatgag tgtggtagca ggaacccgtt
    19921 ttcgtgggga ttttgaagag cgcatgaatc aaatcattga tgatattgaa gctgatggtc
    19981 agattattct ttttgttgat gaactacata ctattatggg atctggcagt ggtattgaca
    20041 gtacacttga tgcggctaac attttaaaac cagcattatc gcgcggcact cttcatatgg
    20101 ttggagcaac aactcaagaa gaatatcaaa aacatattga aaaagatgca gctctttcgc
    20161 gtcgttttgc taaaatatta attgaagaac ctaatacaga agatgcttat cagattttga
    20221 tgggcctaaa attatcttat gagacctacc ataatgtctc gatatcaaat gaggcagtta
    20281 aaacagctgt aaaaatggca caccgttatt taaccagtaa aaatctccct gattcagcta
    20341 tcgatttatt agatgaagct agtgctgctg tgcaaaacat ggtgaaaaaa tcagcacctg
    20401 agactttaac accaatagac caagctctta tcaatggtga tatgaaaaaa gtatctcgcc
    20461 tcttagctaa agaagcaaaa ggtcagatga gaaaaccaac accagtcaca gaagatgata
    20521 ttttggcaac cttgagtaag ttatcgggaa ttccacttga aaaactgacg caagctgata
    20581 gcaaaaaata cctcaattta gaaaaagaac tgcataagcg tgtgattggt caggatgctg
    20641 ctgttacggc tatttcaaga gccattcgtc gtaatcagtc aggtattcga acaggaaaat
    20701 gtcctattgg atcatttatg tttcttggcc caacaggagt aggtaagaca gaactagcaa
    20761 aggcccttgc agaagttctc tttgatgatg aagcagcgct tattcgtttt gatatgtctg
    20821 agtacatgga aaaattcgca gcgtctaggc ttaatggagc acctcctggt tatgtcggct
    20881 atgatgaagg aggtgaactg acacagaaag ttagaaataa accttattca gtcttgcttt
    20941 ttgatgaagt ggaaaaagca catcctgata tttttaacgt tctccttcaa gtattagatg
    21001 atggtatatt gactgatagt cgtgggcgta aggtcgattt ttcaaatact attattatca
    21061 tgaccagcaa tcttggcgca acagccctgc gcgatgataa aacggtcggt tttggggtca
    21121 aagacattca ccaagaccat caagctatgg agaaacgtat tttagaagaa ttaagaaaaa
    21181 cttaccgccc agaatttatc aatcgtattg atgaaaaagt ggtctttcat agtctgaccc
    21241 aagataacat gcgcgatgtg gttaaaatca tggtacagcc cctgattact acattggcag
    21301 aaaaaggtat tacccttaaa attcagcctt tggccttgaa acatttgtcc gaggtcggct
    21361 atgatgagca tatgggggca agaccattac gtcgaacgct gcaaactgag atagaagata
    21421 agctatcaga gcttattctt tctcgagaat tgacaagtgg gcatacgcta aaaattggat
    21481 tatcacatgg caaattaacg tttcacatag cttaatttcc atataaaagg tggatcatcc
    21541 ttgatgtcac caaaaaaaga ggttattctt acaaaaataa cttctttttt cttgactatt
    21601 tttgaccaag tgataaaata gaatataaag ttagcactcg atgaacatga gtgctaactt
    21661 tactaaagat tcttttattg gaggaaaatt tcatgttaaa accattaggc gaccgtgtgg
    21721 tcgtaagatt tgatgatgaa aaagagcaga cagtcggtgg ttttgtcctt gcaggcactc
    21781 ataaagagtc aacacgaaaa gcgacagtcc tcgctgtcag tgaaacgggt gttcgcacta
    21841 ttacaggtga tagcgtgcta ccttcagttt cagtgggtca agaggtttta gttgaaaatg
    21901 ggcatgattt agaagtaacc gtagatgatg agaaagtttc tatcatccgt gaatctgaca
    21961 tcattgctat tgttacaaaa taaaacgaca aatctctaaa tagaaagaag gattgaatat
    22021 ggcaaaagat attaaatttt cagcagatgc gcgtgctgcc atggtgcgcg gagttgatat
    22081 gttagcagat accgtcaaag taacgcttgg tcctaaaggg cgcaatgttg ttcttgaaaa
    22141 agcttttggt tctcccttaa ttactaatga cggggtaacc attgctaaag agatcgaatt
    22201 agaagatcat tttgaaaaca tgggagcaaa attggtgtct gaagtggctt ctaaaaccaa
    22261 tgatattgct ggtgatggga cgactactgc aacagttttg acacaagcca ttgttcatga
    22321 aggactaaaa aatgtgacag caggtgctaa tccaattggt atccgtcgag gcattgaaac
    22381 agcaacagca acagctgttg aagccttgaa agccattgct caacctgtat ctggcaagga
    22441 agctattgct caggtcgctg cagtatcatc acgctctgaa aaagttggag agtatatctc
    22501 agaagctatg gagcgtgtgg gcaacgatgg tgtgattacc atcgaagaat ctcgaggtat
    22561 ggaaacagaa cttgaagtgg ttgaaggcat gcaatttgac cgtggttacc tgtctcaata
    22621 catggtcaca gacaatgaaa aaatggttgc agaccttgaa aacccattta tcttgatcac
    22681 ggataaaaaa gtgtcaaaca tccaagacat tttgccacta cttgaggaag ttcttaaaac
    22741 caaccgtcca ttactcatta ttgcagatga tgtggatggt gaagcccttc caacccttgt
    22801 cttgaacaag attcgtggta ctttcaatgt ggttgctgtc aaagcgccag gatttggtga
    22861 tcgtcgtaaa gctatgcttg aagacattgc tatcttgaca ggtggtacag tgattacaga
    22921 ggatctagga cttgaattaa aagatgctac aatgacagcc cttggacagg ctgctaagat
    22981 tacagttgat aaagatagca cagtaattgt tgaaggttca ggaagttcag aagctattgc
    23041 taaccgtatt gcactgatta aatcgcaatt agagacaaca acttctgact ttgaccgtga
    23101 aaaactacaa gaacgtttgg cgaaattagc tggtggtgta gctgttatca aagtaggagc
    23161 tccaacagag acagctttaa aagaaatgaa acttcgcatt gaggatgctc taaatgccac
    23221 acgtgcagcc gttgaagaag gtatcgttgc tggtggtgga acagcactta ttacggtgat
    23281 cgaaaaagta gctgctcttg agcttgaggg cgatgacgct actggacgta acattgtgct
    23341 tcgtgctcta gaagagcctg tacgtcaaat tgctttaaat gctgggtacg aaggctccgt
    23401 agttattgac aagttgaaaa acagccctgc aggaacagga tttaatgctg caacaggtga
    23461 gtgggttgat atgattaaaa caggaatcat tgaccctgtc aaagtaacac gatcagcgct
    23521 tcaaaatgca gcttctgtag ctagtcttat tttgacaaca gaagcagttg ttgctaataa
    23581 gcctgaacca gcagcgccag cgccagcaat gccagcaggt atggatccag gaatgatggg
    23641 cggcttctaa gctctctata gcattaagga ttatgaaaaa gaagttgaga ctaaaggtct
    23701 gcttcttact atgaaaaaag aacaaagatt ggatttcgac tcatgatatc ccatctttgt
    23761 ttttttagtt gtgatataaa atgccaatct ttgtggttac agactgttaa tgtattggaa
    23821 aatatattgt ttttctttgt catgtgctat catggagcca atgaaaagtt attcccatat
    23881 atgggtgttg gaggtctgtg atgaatcatt ttggagagat ttttaaaacc tttagagaat
    23941 caaggggatt acgattaaaa gatgtcgcaa aggctggtat atcaacctct cagctgtcgc
    24001 gtttcgaaaa aggggagacg gatttaacca tatcgacgtt tatgctgatt ttgaatgaaa
    24061 gtaacatgtc cattgatgag tttatgtatg ctgtccatga ttttcatcgt gacgacacaa
    24121 ctcaagatag tgatggcttg aagtagttgc ttcatgctca actagcatca actgataaga
    24181 aggaaatgtt cacggatatc ttttggcata tccagcatgt ctaagtctgc tatggcatgc
    24241 cattttggga gtccctcacg cgactctgtc agtagctctc cttcaaagga ttcacatata
    24301 aagttgtaat agacatagca ctcttttttt gtcaggcttg ataaagctag aaataccctt
    24361 taattgaagg tttaaagctg tcagatctat ctcttctttt agttctcata aagccgcttc
    24421 aaagaaagat tcacagggtt cgactttacc ttctggctgg acccatcctg ggaagttatc
    24481 gtgttgtcta tggagtcata aaatcatatc gttatgtttg acacacatat tgccccagtc
    24541 tctaaccgtt gctatcacca gattcaccac cttttagtat agtataagaa aaaaggggtg
    24601 aaagaggttt cttgttgttt ttttggctta aggtttcttt aagtcttatc tagtatacta
    24661 atgtcattcc ttaataggat aagtatttgg ttgtagaagt atcgtcttaa actaatgcta
    24721 tctcaacccg attcccatct tattcacccc tcctataccg ataaggtctc acaaagtgtg
    24781 agaccttatt ttttgacttc agctctagtt atggagaaac ttgttgatac aagctttttt
    24841 gggttatggt attatgatct attcaagcct ttcttgtttt tgggtttttc tttaaccaac
    24901 ttggcttcaa tagcttttaa gcgcttgaag gttttttcag cgcgatctag tgaaatctta
    24961 tcagcttttt cttgagcagc tttggggtca ctgacgacta agtcactgat ttctttggtg
    25021 gttttgtctt gttcggctat ccaggttttt tccaagcctt ttatctcatc aatcacttta
    25081 gttccaaatg gttttggatg agcagccacg agatcattaa tgtgtgacac cgtccaatac
    25141 catgacttat cgttatattg ggtgcttttt tcttgatagg cttcataggt tctactgata
    25201 ttgccaaggt atggcaagta aggggcatta cgaggactgc caatagatag ccacatgaca
    25261 ccaccaccca attcagcagg gatgtctttt ttcagttgga aaatatgagc ttccatgaca
    25321 ttaggattgg aaataggata cgcatagccc ttaacagctt ttttggattt tggtttaccc
    25381 ttaccgtcta atgccatctg atcaagtggt ttaagatcaa gcccctcaaa acgattacgt
    25441 tgcagtttca tcgcatcttc tagactaaag gtcttatcag tgctttggag caactcataa
    25501 ttgctgtctt tataagttac ttttgaatca gggtcaagtg atttaatccc tgagaaagag
    25561 cgagagcggt tggcatcgtt tagtggtgga ttgtaagatt tggcaatatg aaatttacca
    25621 tcaacttcga tataagattt ggctttttta gcgacttttt ccacatcttc tgaggcaatc
    25681 gtattttcct tatcgttgaa atcgacatgt ccgagataga aggtatttgg aaaaacagcg
    25741 tatttatcat ctgggaattt aatggcaacg tattggtgac cagagagaat ttccatgtac
    25801 cagatgccgt ctttgtcagc caaggtaaca atatttcctt cagcagctcc tttttcagtg
    25861 actattttag caatcaatgc gacaccttca cgggctgttt tgacacttgg taaaatgaca
    25921 ctggccatag acgattccgc taagccattt ttgacgtaag gatcaatttt ttggatggca
    25981 tcattagctg aagctgatac tgttgcagac atagagacgc cacactcatt aaaaccagct
    26041 tcgtcataaa cgcctttgtt aggtgttaca tcaggaatcg cactatagcg ataagaatgc
    26101 tcaggcaacg ggtactcaaa accattagag aggtctttcc atttttcgcc agcaggattg
    26161 tcctttgcta gacgtacaat gaaattttta ttatgatgtg gctcaagatc ttctgttcga
    26221 ccattaaaga agagaaccgt ctttggttaa atctttgcca ataataaaac cagtacaagc
    26281 ataactaaca ctttgaagcg aaaaggctgt cagaatactt aaaactccaa gtgatatttt
    26341 tttgtttatc atgcgaatcc tcctagtaaa cgataacgct ttcacagaca ttataaaatg
    26401 ctctttttaa aaattcaagt cttttatgaa gtgttttgaa attgttagct atctaaatat
    26461 tatgagaatt ctctcttgaa ttttggctta acggccccta aaaacgtata ggcagtgaac
    26521 tatctaagtt tcttcgaaaa tccattagcc atttatgata taatagtaaa gaaaaacata
    26581 gaaagttggg gtctgttgat gaccaaacca tttcatcata agaaactaaa acaaataact
    26641 ataatagctg caactagcct ttttttattc ctgatcggtg gtgcctttta ctactctaaa
    26701 aatcattgta ttaatgccta tcttaaagct cgatcagccc aatcaggacc agtttttgag
    26761 aatatcaaag catatctagt ctgggatgat actaatgagc agatcacaaa tgacgaggcg
    26821 atgtatacta agtttagaag gtatagtcaa aaagaattga ggcaaaaaaa gcaggattta
    26881 aaagccgcta gtcaagatag tgccgttcaa gtaaagtctg ttggtcgtcg tttttggatt
    26941 tttcctgatt atcggattgc cataaaaccc atggatttaa cgataaaaac gaatgtgcct
    27001 caagcagacg ttcttttaaa tcaaaaaaaa gttgctgttt ctgattcaga acagttctca
    27061 gtcaagcttg atcggctacc aacggcagaa tataccgcaa gtatcagagg caaacacaac
    27121 gggcgaaaca ttaaagtcaa taaatcatat gatggtgata atcccgtgct agatttgagt
    27181 gtgtctttta gaactttttt ggtaacaagc aatgctaagc aaggagatct ttacttcgat
    27241 gataaccata ttggcacatt aaaagatggt caattacaag tagaagatta ccctgttaca
    27301 gaaaacgcac aagcttatat gaaaacaaca ttcccagatg gtgagttaag atcacaaaaa
    27361 tatgctctag ctgatgttga agaaggagca accctggaga ttttagttac agatctttta
    27421 gaagaggaca aagcagggga gctattagta tcagcttttg atcagctgat gcactacctc
    27481 agtacaggtc aagactcatc taacttacgt agcgtctttg aggcagggtc tagcaacgca
    27541 ttttataggg gattgaaaga gtccataaaa gcgaaatttc agacagatac aagaaaagcc
    27601 agccgtctca atattccatc tatccttttg acaacaatga ctcaagtggg caaaacaact
    27661 tacgtgcttg atttcacagc tacctacgaa tttttgtatg acaactcaac agatcctgag
    27721 cagcatacct ctggacatat taatcaagac ttgactggaa aagtgactgt aaaaaaagtt
    27781 ggacagcatt accttatcag ccagtccggc tccaaaaata ttactgttgt taaagaggac
    27841 aatcaactca aagcgccatc tgtctttcct gagtctattt tgggaacgtg gacaggccaa
    27901 gccaatggtt tgagcatcca tatgtctcta gcatcagatg gaacaattac gactaaagtt
    27961 gaagatcaaa aaggcaaccg ttctaaagaa actcggacag ctaaaattag taaagttgaa
    28021 gacaaaggca atggttttta tctttatacg ccagatcctg gaagtgacat aagcgcctta
    28081 gttccagaag gaggattggg gggtgcaaat gtcaaatatg cttatggttt caaaatatct
    28141 ggtaaaacag cctctccagt ggtgtggcag gcagcattaa cacatgaatt tgattatacc
    28201 aagccacttt caggtgtaac tttgcaaaag caaccataaa ggatgcaaag ccacaaagaa
    28261 cagtagaaac aatgttatta ctcaaataca gtgctatgaa aacagataaa ctcaaaaggc
    28321 taggagatta tttcctagcc ttttgagcgt ttaagactgc gtcaaatgta gctgatttag
    28381 cttgcacgca aatgtcttct tgggttagag ggtgttttaa acgtaattga taagcatgga
    28441 gcatcagtcg agcacaatct ttttttccat tagaatacaa aggatcacca aataaaacat
    28501 gaccttgatg ggctaaatgg actcgaattt gatgagtccg tccagtttgt aattgacaat
    28561 tgagtaagct tgccgttttg tggaagtttt tgactagagt tacctcagta atagctttct
    28621 tgccatttat cggatcgaca acacgttttc tgcggtcatg tcgatgacga ccaattggat
    28681 gatggtaagt taccctagga ctgtctaagg atccgtgaac tagtgccaaa tattctcgat
    28741 ggatgtctcg tttttctaaa agacgattaa ggattggtaa gataaaaggt gttttagcaa
    28801 ataaaatggc cccacttgtt tccttatcca gacgatgaac cacatagcag gtctgccccg
    28861 tgtaagcaga cacgtggttg agcagcgcca actctgttgg atcattgccg tgtgttttca
    28921 tcccttcagg tttgttaaca ataatgatgt gctcatcttc ataaaggcag gttacttttt
    28981 cggcctgccc catcacgata atcttttcag gataatcttc gtgatcgaaa aaaagtttga
    29041 cctgatcacc gtatttaaca caactttgcc agttaacagg atgaccatta ataagaacat
    29101 gttttttagt tctcagaaaa tgcctaattt tacggggaat taacaattgt tcctctaata
    29161 atgctttgac cgtcaattct tcaaagggat ttttcagtgt gacagtaaac ccctttgatg
    29221 gtttatttgt tgtcttcatt gagccagtta tggtattttt caacaaggtt gatagccatt
    29281 tgggtggcaa gagcagcaga gaaagcttca gtaccttcac gctcgtcatt agctacctcc
    29341 aagcgagtct catcgtaaat ggcttttaga ctttctgcgg ataaggtttc tttaaaagct
    29401 tggaatttat tcattggtta aacccgtcct tctatgttta atgtgagctc ctgattaatg
    29461 caaggaattc aatgctatta tagcatgttt ctaatcaaaa cgtgccactc aaaaaggtaa
    29521 aaacgttatt ttgctaatcc atctaataag aaagtgtctt aaataagacc tcttgataga
    29581 gtttgtaaca gaaatgatat gaaactaggt gctaacgcag aaatagaaaa caactaacgt
    29641 gttgcgaagt tggaacagtc ataaaaaata gcaagataaa acttatcaac acatagttac
    29701 ctaagacgat gagtcaaaca ggtatgttct ttcaaaacaa ccccatgagg ttgaacgacg
    29761 tatcggaaaa atacggatta gtttggcctt atgataggta tttctctatc gtaaaagaag
    29821 tcaaccaaag gtttttaata taaaatatta agaaaaattg ttataattgt gataaaaaca
    29881 taatcgtaaa atagaggaaa aacaatgaaa acaattagac gttatgatgt taacgaagat
    29941 agagggcata caggccttgt agaagcagga gacttctatt atttaaacta ttgtgtcggc
    30001 aatgttggac aagacattga aagtcagatt aatggagcct ttgacgagat ggagcgccga
    30061 ttagcattgg tggggctcac attagatgca gttgttcaaa tggattgtct atttcgagac
    30121 gtttggaaca tacctgtgat ggaaaaaatg attaaagagc gctttaatgg cagataccct
    30181 gctcgaaaat cgattcaaac ggaatttgca catcacggtg gaccacaagg actactcttt
    30241 caagtggatg gtgtggctta ttcaaagcat atttcgatga cctaatcaag gttactttaa
    30301 gatcatagtg gtataataac gttatgagat ttctagaact tttacaaaag aaattttttc
    30361 ctaaagcata tcaggaaaaa caattcttaa tgcatcaaaa agtgcgttta acgccacaac
    30421 acaatcaaaa gcagtattcg ccaaatgcca atcatttgga ctcatcagct accaaaaact
    30481 cagaacaaga ccctgcaata gctctgcaac gcagtagagc ctatgaagga agccctaaaa
    30541 gtcggcccgc ttggttgcaa aagttggaag ctgttttgcc gtctcctcaa catccaattc
    30601 ggcgtttttg gcgccgctat cacatcggaa aactgctaat gattctgatt ggaactcttg
    30661 tcttactctt aggatcatac ttgttttact tatcaaaaac agctaaagta tctgatttac
    30721 aagatgcctt gaaggctaca acggttattt atgatcacaa aggagagtat gcaggcagtt
    30781 tatctggtca aaaagggagt tatgttgagc tcaacgctat ttcagatgat cttgagaatg
    30841 ctgttattgc cactgaggat aggacttttt acagtaatag cggtattaat cttaaacgct
    30901 tcttattggc agtagttacg gcgggccgct ttggaggtgg ctcaacgatt acacagcaac
    30961 tggctaaaaa tgcttatctc tcacaagatc agacaattaa acgaaaggcc agagagtttt
    31021 ttttggcgtt agagttgacc aaaaaataca gtaaaaaaga tattcttact atgtacctta
    31081 acaactccta ttttggaaat ggagtttggg gagttgaaga tgccagtcaa aaatattttg
    31141 gaaccacagc tgctaactta acactggatg aagctgccac attagcaggt atgctcaaag
    31201 gacctgaaat atataaccct taccattctc taaaaaatgc tactcaccgt agagatactg
    31261 ttttaggagc gatggttgat gccaaaaaga ttacccaaac aaaagctcaa caagctagag
    31321 cagtagggct aaaaaatcgc ttagctgata cttatgttgg taagacagat gactacaaat
    31381 acccatccta ctttgatgct gttattagtg aagcaatagc aacttatggt ctttcagaaa
    31441 aagacattgt taataatgga tacaaagttt acactgagct agatcaaaat taccaaactg
    31501 gcatgcagac gacttttaac aacgatgaac tatttcctgt ttcagcttat gacggtagct
    31561 ctgctcaagc agctagtgtt gctttagatc ctaaaacagg aggtgttaga ggtctgattg
    31621 gtcgtgtgaa tagtagtgaa aatccgactt tcagaagttt taactatgcg actcaagcaa
    31681 aacgtagtcc cgcatcaaca atcaaaccac tcgtggttta cgcgccagcc gttgcttcag
    31741 gatggtcaat tgaaaaagaa ctaccaaata ccgttcaaga tttcgatggc tatcagccac
    31801 ataattatgg aaattatgaa tcagaagatg ttcctatgta tcaagcatta gcaaactctt
    31861 ataatattcc agcagtttct acattgaacg atatcggaat cgataaagcc tttacctatg
    31921 gtaaaacatt tgggttagat atgagctctg ccaaaaaaga gttgggggta gctttaggtg
    31981 gcaacgtgac aaccaatcca ttggagatgg ctcaggcata tgctgccttt gccaataatg
    32041 gagtaatcca tcctgcgcac ttgattaacc ggattgaaaa tgccaggggt gaagtgctta
    32101 aaacctttac tgataaggct aaacgtgttg tcagccagtc tgttgcagat aagatgacag
    32161 ccatgatgct aggtaccttt tcaaatggaa cagcagtcaa tgctaacgta tatggctata
    32221 cactagctgg taaaacaggg acgacagaaa ccaacttcaa tcccgactta gcaggcgatc
    32281 agtgggttat tggttataca ccagatgttg ttattagtca atgggtagga tttaatcaga
    32341 ccgatgaaaa tcattatcta acggattcaa gtgcaggcac ggcctcagct atttttagca
    32401 ctcaggcatc ttacattttg ccttatacca agggcagcca atttcatgta gataatgcct
    32461 acgctcaaaa tggtatttca gctgtttatg gagtcaatga aacaggtaat caatcaggag
    32521 ttgacactca atctattatt gatggtttaa gaaaatcagc acaagaagct tcgcaatcac
    32581 tatcaaaagc agtcgatcag tcagggttac gtgataaagc ccaatctatt tggaaagaga
    32641 ttgttgacta ttttagatag cttgcagtat tttagagatc gtgttaaaat aatagttacg
    32701 gaggcgttat ggcacagaaa aaagcgagtc tagcgtgtgt cgaatgtggc agtcgtaact
    32761 actctatcgg agtgagtagc acgcctaaac caacacgtct agaagtaaat aaattttgca
    32821 aatactgcaa aacatatacc ttacacaaag aaacacgtta aaaaggagag cctgatggga
    32881 ttcattagcg ggacttttaa agtcttaaaa gacacaacat ggccaaatcg taaacaacgt
    32941 tggaaagatt ttatctcagt tcttgagtac acagctttct ttacggtgat tatctacatc
    33001 tttgaccagc tcttagcaaa gagtgtatta gcactgatta atttattcta ggtcaagatt
    33061 ggtagaaatg ataagcttgc ttggaaaagc ctaggctggg agtattccca gccttttttg
    33121 tagtatcaat aatctgatta gtaagctttt ttaaagccca tactggtttg agctttaaaa
    33181 aagtataaag gtaaaggcaa tgtagcaacg atctccaaac caagttcact aaattagctt
    33241 gtaacagagt catcgcataa acagcctggc ctcacttgct tagcacatta aaaatagcaa
    33301 tgaatattat ggttgaggaa aacagcctga tagtctgcta aatcttcggg atgataagcc
    33361 ttgacctcag ccatctcata ctccctacct agaagtttgt acttgttttc tccaaattga
    33421 tggaaaggta acagttgcac ttggtcaatc tcaagctgat taaagagctc tgagaaggct
    33481 ttagcatcat ctagggaatc attaaattgg ggaataacag ggatgcgcaa gacgatttct
    33541 tttccagctt gaaaggcata atgaatattt ttgataatca agtcattacg aaccccagtc
    33601 actttttggt gtctgagctg attataatgt ttcaaatcgg tatagataaa gtccacgtag
    33661 tcaataaggg tgacaaattg ctcgtgtttg gcaaaggcgg tggtttcaat tgcggtgtga
    33721 agacctgctg ctttggctgc ttttaacagg gctaaggcaa agtcaaactg agcaaagatt
    33781 tccccccctg acagggtcat gcccccacct gactcttcgt agaaatcaag gtctttaagg
    33841 acttcttcga tcacctcgtc cacggttttt tcttctccaa ctattttagt attaagccca
    33901 tcacttgtta acatctgctc aggcgctttt tgttgggatt cgggattggc acaccaagga
    33961 catctcaagg ggcaaccttt taaaaaaacg gttgtccgaa taccagggcc gtcatgaata
    34021 ctaaaatgtt ggatgttgaa aacaataccg cgatcagtca taagtgtgaa ttcctttcgt
    34081 tgtaaaacca tcataccaga taaacgtaaa taaatcaatt acgaatgaaa gtaaatatcc
    34141 cttttctttt aagaaaataa ctggtacaat gaaagggagg tgaatgatga atcgattaga
    34201 acgtattatt caactggttt cccagaagaa aaaaatagat gttaacagtt tatcagagca
    34261 attagaagtt tcgaaagtaa ccattcgaaa agaccttgat aagcttgaaa gtaagggctt
    34321 gttgcgacgg gaacatggct atgcggtgct aaacagtggc gatgacctca atgtacgctt
    34381 gtcctacaat tacaacatta agcgacggat tgcagaaaaa gcagctgaat tggtgcaaga
    34441 taacgatacc attatgattg aatctggctc aacctgtgct cttttggcag aagtgctttg
    34501 ccagaacaaa cgaaatatta aagtcattac caattcgtgc ttcattgcca actacattcg
    34561 tcaatatagt agctgtcaaa tcattttact gggcggttat taccagccca attcagaggt
    34621 gactgttggt cctttattga aagaaatgat atcccttttt catgtcaatc gtgtctttgt
    34681 tggaacagac ggtttcaaca aagatcttgg ctttatgggc aaggacatga tgcgctcaga
    34741 aggggtgcgt tacatggcag atgctgctga ggaagtggtg attctgaccg attccagcaa
    34801 gttttcaaaa accagtctgg tacaccagtt gtcattagct gatgtcaatc gcgtcattac
    34861 agaccaggca ctagacaagc aaacacaaga gttattaagt gctagtggtc ttgttcttga
    34921 ttttgtttct tagaaaatag gtggctagat gaaagaagaa cgcagacggc tccttgccaa
    34981 ggtggcttac ttgcattata ttcaaggcaa gagccaaacc ttgatttcaa aggaaatgaa
    35041 tatctaccga acaacggttt gtcggatgtt ggcaaaagcc aaggaagaag gcattgttcg
    35101 gattgaaatt gccgactatg atgctgattt atttgcttta gaagaatacg tgcgacagca
    35161 gtatggcttg gaaaaaatag accttgtgcc caaccaggtt gaagataccc caatggatac
    35221 cttgacaaat gttgctaaaa cagcagctga ggtttttaga catgttgtta aagatggcga
    35281 taagatcggt ctgtcctggg gagcgactct ttcttgcttg atggatgagt taaatccaaa
    35341 agcgatgaaa gatgtgttta tttatccttt ggcaggagga cctagccata ttaatgccaa
    35401 ataccatgtc aataccctgg tttaccgctt ggctcgcatc tttcatggta atagcgcttt
    35461 tatgaacgct atggtcattc aagaagacaa acacttggct aagggaatct tacaatctaa
    35521 atactttaac gacatcttaa caagctggga ccagctagat cttgccttag taggaattgg
    35581 tggggagcct aatagccttg agcagagtca atggcgtgat ttattaacca gctcagatca
    35641 tgaccaactc aaatatgaaa aagccgttgg tgaagtttgt tgccgtttct ttgatcaggc
    35701 aggtcagcca gtttacactg gcctacagga tcgaactatt ggtatttcgc tagaacagtt
    35761 gaggcgtgtc cccaaaacaa tggctgttgc aacaggtaaa cacaaggcta aggcaatatt
    35821 ggcagcctta aaagcaggtt ttatcaatta tctagtgacg gataaagaga ccatgctagc
    35881 tgttttagcg ttagatgaag atattgatct taataacgtt cttctttaat agaaattcaa
    35941 agatactatg atatttatag aggcccaaga ccaaacggtc agggcttttt tgtttgatgt
    36001 gttgataaaa cagagattgc tcaaatgtgc agttaatgta ttggcacaaa agtgcattag
    36061 ccaaaatata gcacaaaata tattgaccct aaaaacaaaa atgatacaat aaacttacca
    36121 acgaaatgta aacgattaca aacgcaataa catccccttc gaaaaaaaga ctcattgccg
    36181 ttacatcaca tgaaaaagaa aaaaaggaga caccaatgca agttattgta ccagaccaaa
    36241 tcattatggg cttaatttta aatgcaggcg atgccaaaca acatatctac caagctctga
    36301 aatgtgctaa agaggacgat tatgccacta gtgaaaaaga gatggcctta gcagatgatg
    36361 ccttattaga agcccacaat ttacagaccc agtttcttgc ccaagaagct agtggtaata
    36421 agtcagagat tacagcgctt tttgttcact cacaggatca cttgatgacg accattacag
    36481 aaattaatct cgtcaaggag attattgacc ttcgtaaaga attggcaact aaataagttt
    36541 tcatgactaa aaaggagatt gacatgatta aaattggatt gttttgtgca gcaggatttt
    36601 caaccggtat gttggtgaac aacatgaaag tagctgctga aaaaaaaggc attgattgtc
    36661 agattgaagc ctatgctcaa gggaaattag cggactatgc accattactt gatgtggcac
    36721 ttttaggccc acaggttgcc tatactctgg ataaatcaga agctatttgt aaagacaatg
    36781 atatccctat tgcagttatc ccaatggctg attatggaat gttagacggc aacaaggtgc
    36841 ttgatttagc ccttagcctt gttaaagaat aggagtcaat catggcaaaa atgaatatgc
    36901 aaaacatcat catgccaatc atgacatttg tgaatatgcg cggcatcatt gccttaaaag
    36961 acggtatgtt agccatttta cctttgaccg ttgtggggag tcttttcctg attgctgggc
    37021 agattccttt ccaaggggtt aatgatgcca ttgctagtgt gtttggtgct gactggacag
    37081 aaccctttat gcaggtttat catggaacat ttgctattat ggggttgatt tcctgttttg
    37141 caattggcta ttcttatgct aaaaactcag gtgttgaacc tctcccttca ggggttctat
    37201 ccttgtcagc cttctttatt ttattgagat catcttatgt tccagcagaa ggtgaagcta
    37261 ttggagatgc tatcagtaag gtttggtttg gtggtcaagg gattattggt gctattgtga
    37321 ttggtttaac ggtcggagct gtttacacaa catttatccg tcgtcatatc gtcattaaaa
    37381 tgccagatca agtgccacaa gctatcgcca aacagtttga agccatgatt ccagcctttg
    37441 tgatctttac cttgtcaatg cttgtgtaca ttattgccaa gtcagtaaca ggtggtggca
    37501 cctttattga aatgatttat gatgtcattc aggtaccgct gcaagggtta acgggctctc
    37561 tttatggcgc actaggtatt gccttcttta tttcctttct ttggtggttt ggcgtgcatg
    37621 ggcaatctgt ggtcaatgga attgtcactg ctcttctctt atcaaatcta gatgccaata
    37681 aggccttgat ggcagcaggt gagttatccc tagacaaggg tgcccatatt gtaacccaac
    37741 aatttttaga ctctttcttg attctatcag gttctggcat tacctttggt ttagtggtag
    37801 ctatgatctt tgcggctaaa tccaaacaat acaaggcttt aggtaaggtt gcagccttcc
    37861 cagccctctt taatgttaat gaacctgtcg tctttggttt tccaattgtg atgaatccag
    37921 tcatgttctt gccatttatc ttggttcctg tcttggcagc tctcacagtt tatggcgcca
    37981 ttgctattgg tttcatgcag ccctttgcag gagtgaccct tccgtggtca acaccagcca
    38041 ttatctcagg gttcatggtt ggtggctggc aaggagctat tgtgcaaatt cttatactca
    38101 tcatgtcaac gttggtgtac ttcccattct ttaaaattca agataatatg gcttatcaaa
    38161 atgaacaagc tagtgaagag tcatgattta gcgtccacac aaattcttga gaccatctcc
    38221 agttagaggt ggttttttag aaaaaggaga gcgacttatc aggcctatat tgcacaatag
    38281 tgcaaaataa agtgactatc tcttcttatg gttaaggata cgcaaaagtc ctaatatatg
    38341 ataaaatagt tacgaaagaa acatttataa tttcgtaaga aagaaggaga ccccgcatga
    38401 ctgaaacaaa aatcccttat tttggacatt taacagacag aatgactcac tatcgtgaag
    38461 ctgtgttaga caagaaacct tatattgatg ctgagcgtgc tattttagcc actgaagcct
    38521 atcaaaaaca ccaaaataag ccagcaaacc tcaaacgcgc ttacatgctt caaactattt
    38581 tggaaaacat gaccatctat attgaggatg aaagcctcat tgctggtaac caagcctctt
    38641 caaacaagga tgcaccgatt ttcccagaat acactctgga atttgtcctc aacgaacttg
    38701 atctttttga aaaacgagat ggggatgtgt tctacattac cgaagaaacc aagcaacagc
    38761 tccgagatat tgccccattc tgggaaaaca ataacttacg tgctcgctgc ggggtcttgc
    38821 taccagaaga agtgcaagtg tacatggaaa caggtttctt tggcatggaa ggcaagatga
    38881 actctgggga tgcccattta gcggttaatt accaaaaact cttggaacat ggcttaaagg
    38941 gatttgaaga gcgggcacga gctgccaaag ctgcgcttga tttgaccatt cctgaaaaca
    39001 ttgacaaata ccatttttac gactctgttt ttattgtcat tgatgcagtc aaaacttatg
    39061 ccaaacgcta tgccaagttg gctagagaac tagcagaaac cgctagtcca gaacgtcaag
    39121 cagaattgtt agacatcgcg tgcatttgtg acaaagtgcc ttatgaacca gcagcaacgt
    39181 ttgcagaagc tgtacaatcc gtctggttca ttcagtgtat cttgcaaatt gaatcaaacg
    39241 ggcattccct atcttatggc cgctttgacc agtacatgta tccttatgtc aaagctgatt
    39301 tggaggctgg ccgtgaaaca gaagacacaa tcgttgagcg tttgaccaac ctctggatta
    39361 agaccttgac cattaataaa gtacggagcc aagcccacac cttctcatca gcagggagtc
    39421 cactttacca aaacgtgacg atcggcggtc aaacacgcga taaaaaagac gcggtcaacc
    39481 cactgtctta ccttgtccta aggagtgtgg ctcaaaccaa attgccacaa cctaacttga
    39541 ctgttcgtta ccacaaaggc ctagacaata cctttatgaa cgagtgtatc gaggtcatga
    39601 aacttggttt tggtatgccg gccatgaaca acgatgaaat catcattcca tctttcatca
    39661 aaaaaggtgt ctcagaagaa gatgcttatg attactcagc cattggctgt gtggaaacag
    39721 cagttcctgg aaaatggggc taccgttgca cggggatgag ttacatcaac ttccctaaaa
    39781 ttttgctgat taccatgaat gacgggattg acccagcatc aggcaagcgc tttgcaaaag
    39841 gacacggtca cttcaaagac atgacctctt atgaagaatt aaaagcagca tgggatgcca
    39901 ccctgcgcga aattacccgc atgagcgtca ttgttgaaaa tgccattgac ttaggtcttg
    39961 aacgtgaagt accagatatt ctttgctcag ccttgacaga tgattgtatc ggtcgtggca
    40021 agaccttaaa agaaggcgga gctgtttacg actatatctc aggccttcaa gtcggtattg
    40081 ccaacctatc agactcccta gcagcgctga aaaaattagt gtttgaagaa ggtcaattaa
    40141 ctccagaaga actctggcac gcccttgaaa gtgactttgc tggagaacgc ggagaagaga
    40201 tccgacaaat gctcatcaat gacgcaccaa aatatggtaa tgatgatgac tacgcagata
    40261 gtttagttgt cgaagcttac gacacctaca ttgatgaaat tgccaaatac ccaaataccc
    40321 ggtatggccg tggcccaatc ggaggtatcc gctattctgg gacatcatca atctcagcca
    40381 atgtcggaca aggaaaaggg accttggcga caccagacgg tcgccatgca gggacacccc
    40441 tagcagaagg ttgttcacca gaacacagca tggacaaaaa aggccctact tcagtattga
    40501 aatctgttgc taaattacca acagatgaga ttgtcggagg agtactactc aaccaaaaag
    40561 ttaacccaca aaccctggcc aaagaagaag acaaactgaa attaatggcc ttacttcgta
    40621 ccttctttaa tcgcctacac ggttatcata tccagtacaa tgtcgtgtca cgtgaaacct
    40681 tgattgatgc ccaaaaacat cctgaaaagc accgcgacct cattgtccgt gttgccggct
    40741 actcagcttt cttcaatgtg ctctcaaaag caacccaaga tgacattatt gaacgtacag
    40801 aacacaccct ttaggagaaa ataagtatgg aatacatgtt agacacttta gatttagaag
    40861 ctattaaaaa atggcatcac attttgcctc tcgcaggtgt gacctcaaac ccttctattg
    40921 ccaaaaaaga aggtgagatt gatttctttg aacggattcg agaagtccgt gctattattg
    40981 gtgacaaggc ttctattcat gttcaagtga tcgcccaaga ttacgaaggc atcttaaaag
    41041 atgctgctga aatccgcagg caatgtggag atagtgtgta tgtcaaagta cctgtaacca
    41101 cagagggcct tgcagccatt aaaaccttga aagccgaagg ctatcatatc acagcaaccg
    41161 ctatttatac aactttccaa ggactattag ccattgaagc tggcgctgat tatttggctc
    41221 cttactataa ccgtatggaa aatctcaata ttgatccaga agctgtcata ggacaattag
    41281 cagaagctat taaccgcgag aatgctaata gtaagatttt ggcagcaagc tttaaaaatg
    41341 tggctcaggt caataaatcc tttgctctgg gagcacaagc catcactgct ggcccagatg
    41401 tgtttgaagc aggatttgcc atgccatcta ttcaaaaagc ggttgacgat tttggcaagg
    41461 attgggaagc cattcatcac cgcaagagca tttaagaaat agcatcagta gtaatcacat
    41521 cattaggaat cacagataaa ggagttcaac gatgaaagta tttgcaagtc catctcgtta
    41581 cattcaaggt aaaaatgcct tgtttaccaa tgctaaaacc ctaaaacaac taggggatag
    41641 ccccatttta ctgtgtgatg acgtggtgta tggcatcgtc ggagaaagat ttgaaagcta
    41701 tttgatagat aatggcatga ctcctgttca cgtagccttt aatggcgaag cctcagataa
    41761 tgaaatcagc cgcgtggttg ccattgccaa ggaaaatggc aatgatgtta ttattggact
    41821 tggtggtgga aaaaccattg acagtgctaa ggctatcgct gacttacttg ctgttccggt
    41881 gattattgcc ccaaccattg cttcaacaga tgccccaacc tcagccttat cggttattta
    41941 taccgatgaa ggagcctttg aaaaatacat tttctattca aaaaatccag atcttgtttt
    42001 ggttgacaca caagtaatct gtcaggcacc aaaacgatta ctggcgtcag ggattgcaga
    42061 tgggttagca acatgggtag aggcgcgtgc tgttatgcaa aaaaatggag acaccatggc
    42121 aggtggtaat caaaccttgg caggagttgc cattgccaaa gcctgtgagc agaccttgtt
    42181 tgcagatggc ctaaaagcga tggctagctg tgacagacaa gtcgtgaccc cggccttgga
    42241 aaatgtcatt gaagccaata cacttcttag tgggcttggt tttgaaagtg cgggtctggc
    42301 tgctgcacat gccattcaca atggctttac agcgctgaca ggtgctattc atcaccttac
    42361 ccatggtgaa aaagtcgcct atggcacgtt gacccaactc ttcttggaaa atcgttcgcg
    42421 tgaagaaatt gaccgttaca tcgactttta ccaagccatt ggcatgccaa caaccctcaa
    42481 agaaatgcat ttagacacgg ctactcaaga ggatttctta aaaattggcc gtcaagcaac
    42541 catggcaggc gaaaccatcc atcaaatgcc atttgttatc agtccagaag atgtagcagc
    42601 ggctttggtt gctgttgatg cctatgttac gagtcgatag gctaaccaaa aagagatttc
    42661 ttatttgcca gataacctca aaaaaacaag tctagggagt cacttcctag acttgtttta
    42721 cttattgttg gttggtaata gcacttttag cagggtcatt gtgggcaata cgactggcag
    42781 ctgcagcagc aatggcgcta acaatatcat ctaaaaaggt atggcaggag ttgccatctt
    42841 tatggttgag tttgtcaaca attcccggtt ttgtcttgtc cagataccca taattggtaa
    42901 aaccgataga cccatagagg ttaacaatgg ataaggccaa gatttcatca atcccataca
    42961 gcccttggtc ggttttcaag atactaagga gtggctcaga cagctggttg gcttcagcca
    43021 atttatccaa ttctacccca gtgataatag cattttgcac ttctcgtttt gcaagcaccg
    43081 cctcaacgct ctctaaacat tctgccatgg tcaaattagg aatataatca ttctgcaaaa
    43141 aaagcaccag ctctgcaata gcttctaaag aaacccctcg ctcagccagt aattgataag
    43201 acacttctcg taggtgatgg tcagttgaca tgtgagacct cctttttttc tttattgtaa
    43261 cataaaagat tttaagaaac ctctacaaca gctaaagagg ggatagttct tttttaagag
    43321 atgttgacta ctgagatccc ctacttggta aaagtcaaag aaacgatagt aaagtaacca
    43381 tcttacctag gcctaaatac aatcaccacc cctaggtgac acacagcacc tatttcaaaa
    43441 atgatattag tatggcaaaa caaaaagaca acgccttctt ttttctcctt actatctcct
    43501 ttaattttca tattttttaa aaaaactatt gataaactag ttaagtaagc gtatactatg
    43561 gttagtgagc gaaattagaa aagaggacaa gcatatgaat ctacttggat caagacgggt
    43621 tttttctaaa aaatgtcggc tagtgaaatt ttcaatggta gctcttgtat cagccacaat
    43681 ggctgtaaca acagtcacac ttgaaaatac tgcactggca cgacaaacac aggtctcaaa
    43741 tgatgttgtt ctaaatgatg gcgcaagcaa gtacctaaac gaagcattag cttggacatt
    43801 caatgacagt cccaactatt acaaaacctt aggtactagt cagattactc cagcactctt
    43861 tcctaaagca ggagatattc tctatagcaa attagatgag ttaggaagga cgcgtactgc
    43921 tagaggtaca ttgacttatg ccaatgttga aggtagctac ggtgttagac aatctttcgg
    43981 taaaaatcaa aaccccgcag gatggactgg aaaccctaat catgtcaaat ataaaattga
    44041 atggttaaat ggtctgtctt atgtcggaga tttctggaat agaagtcatc tcattgcaga
    44101 tagtctcggt ggagatgcac tcagagtcaa tgccgttaca gggacacgta cccaaaatgt
    44161 aggaggtcgt gaccaaaaag gcggcatgcg ctataccgaa caaagagctc aagaatggtt
    44221 agaagcaaat cgtgatggct atctttatta tgaagccgct ccaatctaca acgcagacga
    44281 gttgattcca agagctgtcg tggtatcaat gcaatcttct gataatacta tcaacgagaa
    44341 agtattagtt tacaacacag ctaatggcta caccattaat taccataacg gtacacctac
    44401 tcaaaaataa taccaaaagg ctagacctct gctcactagg cctagctttt tacatcaaaa
    44461 aaagcaatga ctatagaaag taaaaatact agaaaaagca atgattgccg tcattgcttt
    44521 ttatgatttg tccaaaagta aaaagcaaat tgaaaaaatc gccctggagc tgttgagata
    44581 aactacacca tttattaaga taccaaatca aaaagctaac accataagag cgttagcttt
    44641 ttaatgagcc tcaggacagt ttatgtttaa tggcttctag gtaggtttga aacatatgat
    44701 ggatcgtttt gcaattgagt aattggaaga tctccaagat ctgcacacac ttttgctcag
    44761 caccctcttt accatttatg aggccaataa tgccatcaaa aaaagacaca caacaccgtt
    44821 catataagca atcatcattt agctgataat cttcaatttt tgccaaaatc tcagaagctt
    44881 tatcatactc ttgtcgctga ataaacaaaa tcaacatatt gacaaacatc cgaatcgatt
    44941 cattcccata ataccttagg gtattgtatt tatcgaggtt caaaataact tttgaaaaca
    45001 ccatctcaat aaagcaagac tcaaaaataa acatacaatt attaaaaagc acagtctcat
    45061 agtgactcca agtttcaata ttaataagat agtttgacaa ataagtccgc tctgtcagac
    45121 agtcttcctc agtaagagtt gctaataaca ccttgaccaa ggcaaaaagg ttcttttcct
    45181 ttgttgactt actatcttta taagaatcaa ggatatgatt taaaccttct atgtttcggc
    45241 attcaaaata atgttttgcc gtatccatat caataaattc tttgtattgt ttaaagttat
    45301 tactaataaa gagaaactca tcaacattga cattcaagtt gtctaagata taaagtaact
    45361 ttttcgaaga aatgtcaaga ttatttttaa taaaacgata atacgtttgc ctagtgagat
    45421 aatcaccaca aacttgttta atcgaaatgt tttttgaatg cctaatgaat tcaacggttt
    45481 caccaatttc catatgtcaa gccttcctag ttgatgtcaa aaatacgtta tgcatgtacc
    45541 taatacgtaa caagttgaat gtttcggatg atagtcggtt atgatgggta cataaggtca
    45601 gtagccagat gcgatagttt tatcaactgt catatgttaa acctttctaa tctaatagat
    45661 gtaaaaaata cgttacgtgt gtacctaata cgtaacaaaa taatgggtta gcaaaataag
    45721 cagctatgat atagccataa ggttaaaagg aggcgcctac tatgtggtta ttgttactat
    45781 ttttgtagtt ccttttgcaa aatggtagta gataaaaatg agaagtcaat aaaagcattg
    45841 acaaacaaaa gaatcatttt gtttatatta tcagtatttt taagtttctt gtcaactgaa
    45901 atgagcatct actagccaca atagtaacta aaaggctaat tgtcagtaaa aatgagataa
    45961 atcagccagg aaaaagccta cgagtcaact aatggacaac ccaaaaaaag acaaaggact
    46021 ttcacttggt gttgtggacc ctatcacgat ccttatcaca gaatcagtta ttaacaaaat
    46081 gagaacggtc ccatatcatc taaaaaaact gtcaagcaca acctattgtt tgctagctga
    46141 tcttgcctat cagtctgcct agtagatacg gcagaagata agagatcaac caaaagatga
    46201 taagtgcaac gactcatagc gtcttttgac caaaaccaat taggctcaca tgagatgaga
    46261 ataattgggt tgggttgtca gtgtcaacta accgtgttat tgtctattac cattcatggt
    46321 atcagcgaca tcgtatgata accatacgat tcagctaagt aaggaggtgt gtccaatgta
    46381 ccgttaaaag caaatgcagt agattaactt attttgaaag aggtataaaa aaatgaataa
    46441 aaagaaatta ggtatcagat tattaagtct tttagcatta ggtggatttg ttcttgctaa
    46501 cccagtattt gccgatcaaa actttgctcg taacgaaaaa gaagcaaaag atagcgctat
    46561 cacatttatc caaaaatcag cagctatcaa agcaggtgca cgaagcgcag aagatattaa
    46621 gcttgacaaa gttaacttag gtggagaact ttctggctct aatatgtatg tttacaatat
    46681 ttctactgga ggatttgtta tcgtttcagg agataaacgt tctccagaaa ttctaggata
    46741 ctctaccagc ggatcatttg acgctaacgg taaagaaaac attgcttcct tcatggaaag
    46801 ttatgtcgaa caaatcaaag aaaacaaaaa attagacact acttatgctg gtaccgctga
    46861 gattaaacaa ccagttgtta aatctctcct tgattcaaaa ggcattcatt acaaccaagg
    46921 taacccttac aacctattga cacctgttat tgaaaaagta aaaccaggtg aacaatcttt
    46981 tgtaggtcaa catgcagcta caggatgtgt tgctactgca actgctcaaa ttatgaaata
    47041 tcataattac cctaacaaag ggttgaaaga ctacacttac acactaagct caaataaccc
    47101 atatttcaac catcctaaga acttgtttgc agctatctct actagacaat acaactggaa
    47161 caacatccta cctacttata gcggaagaga atctaacgtt caaaaaatgg cgatttcaga
    47221 attgatggct gatgttggta tttcagtaga tatggattat ggtccatcta gtggttctgc
    47281 aggtagctct cgtgttcaaa gagccttgaa agaaaacttt ggctacaacc aatctgttca
    47341 ccaaatcaac cgtagcgact ttagcaaaca agattgggaa gcacaaattg acaaagaatt
    47401 atctcaaaac caaccagtat actaccaagg tgtcggtaaa gtaggcggac atgcctttgt
    47461 tatcgatggt gctgacggac gtaacttcta ccatgttaac tggggttggg gtggagtctc
    47521 tgacggcttc ttccgtcttg acgcactaaa cccttcagct cttggtactg gtggcggcgc
    47581 aggcggcttc aacggttacc aaagtgctgt tgtaggcatc aaaccttagt atggaaatgc
    47641 atttcgttag aacagaacct gaggcacgcc gcatagctga aaccttttgt gccgaaaaca
    47701 cacaaacaaa aacccctatg cgcgtgcagc agttaagcta tccatcagac acagatcact
    47761 caggtggtga gctatacatc tatgctttgt ctcctgctgg atttatcatc gtatcaggag
    47821 acaccagagc gcacaccatt ttaggctatt cttttgataa taacctagac ctcaaccatg
    47881 ataatgtcag gagtatgata gaagcttacc aaaaacaaat caactctttg gattgatcgg
    47941 tcaaaggagc ttttgctccc tcaccactcg tttaagacga ccgtgtttct aaaataccac
    48001 taccttttaa gtttcacgcc gacctaagca agtgtttgtc tcatggagca gactgtttcc
    48061 atcgaaaagt cacccattga taaaggaggt catcaacgcc tactaatgat gacttcccta
    48121 agatgccaag gtaaaggact gagttctgta gagatgggac tcagtccttt tacgattttt
    48181 gagagttatt ctagccatac cgtggcaaga aaacaacact caaaaatagc caacgtcagt
    48241 ttctgttcat acatgactac agccaaacac cacaacctaa cctatcctaa acacagtggc
    48301 tttctaacga acagtcacaa cgagcagcaa caccaaaaag caagattaag ctacgtttaa
    48361 gactaatgat ataagataac agtaattatt aatgagaaaa gaggctcaaa aggacatgaa
    48421 acaaatgaat aaactcatta caggagtggt aacgctggcg acagtcgtga ccttatcagc
    48481 ttgtcaatca tcacacaaca acaccaaact cgtctcgatg aaaggagaca ccatcactgt
    48541 cagtgacttc tacaatgaga ccaaaaacac agaactcgca caaaaagcca tgttaagctt
    48601 ggtgattagc cgcgtttttg agacacaata tgccaacaaa gtctctgaca aagaggttga
    48661 aaaagcctat aaacaaaccg cagaccaata cggtacatcc tttaagacag tcctagcaca
    48721 atcaggctta acgccagaaa cctataaaaa acaaattcgc ctcacaaaat tagtcgaata
    48781 tgccgtcaaa gaacaagcca aaaacgaaac catctcaaaa aaagactacc gtcaggccta
    48841 tgacgcttat accccaacca tgaccgcaga aatcatgcag tttgaaaaag aagaggatgc
    48901 caaagcagcg cttgaagccg tcaaagctga aggggcagac tttgcagcta ttgccaaaga
    48961 aaaaaccatt gcagccgata aaaaaacaac ctatacgttt gactcaggcg aaacaaccct
    49021 accagcagaa gtagttagag ctgcatcagg cctcaaagaa gggaacagat cagaaatcat
    49081 cacagcgctt gatccagcca tctcaaaacg cacctaccat atcatcaaag tcaccaaaaa
    49141 agcaactaaa aaagcagact ggaaagcgta ccaaaaacgc ttgaaagaca tcattgtgac
    49201 tggcaaatta aaagaccctg acttccaaaa caaagtcatc gctaaagctc ttgataaagc
    49261 aaatgtcaaa atcaaagaca aagcatttgc caatatctta gcccagtttg caaaacctaa
    49321 ccaaaaacaa cctgcccaaa aatagaaggt tgccagttta tttccctaag gttgcttaaa
    49381 aagacagccc tagccatcac tccccttttc aaaacaccga taatggaaac gtgtcctata
    49441 ctgatggtct agggcaatgt cataaagcta aagactctat ccaaataagg atagagtctt
    49501 taatatttaa aaaccagtca gcaaaaaaat tcacgctaag cccctagaat gaggcttagc
    49561 gtgaatggta tcagtgatag tccgttaaac tagctgattg ggagtcagaa actctaacta
    49621 cccaatctga ctataccccc agtaccagag gtgtctcatc gcagaagtag caatcagata
    49681 atcgtctgat aagctcttgt cctcaagcaa ctgatgagta tcgtcgcacg ggctatgagc
    49741 tgccggtggc tgatagctag taggctcatc agccaaaact tttttggagt aacgctttgg
    49801 tctcagacgg cgccagaggg ttgagagagg ggtgagaaaa aaacgatggg tcatcttggc
    49861 ctccttgtct aatgatagtc acgttaacag acaaaagtgt caataatgtc attttaagga
    49921 gaaaaagatt aaaaatcaag gtcacaaaac aatctttaaa taaaaatgat gaccctatat
    49981 ttattgagtg agcacatttt ttggatgatg tatgctttca tcaaatagag gttttttcat
    50041 gacaattgct agcatttcgg tgtaaaataa aggtaataac cagcaaagga gcaacccatg
    50101 acaaagcaag atcagttaat cgttgaaaaa atggaacaaa cctatgaggc ctttagccca
    50161 aagctagcaa atctcataga agccctagat gcctttaaag agcattatga ggaatatgcc
    50221 acacttagaa atttttacag tagtgacgaa tggtttcggc ttgcaaacca accttgggat
    50281 gatatcccgt gcggtgtcct atctgaagac ctcctctttg atatgatcgg tgaccataac
    50341 caactactag ctgatatctt agacttggcc cctatcatgt acaagcatat gtaaccatcg
    50401 ctaacgtcac agatactacg atgacaggac aaaaaaagct tgaaaatctc aaaaaaaaca
    50461 gataaaaaac agataatcgt tagaaaaaca gtagatgcgt ctgttaaact aaaggtatca
    50521 aaacaaaagg agcatttcat catgaaattc aaaaaagtat tagtcattcc tgcattagca
    50581 ttagcagcaa catgcttttt aacagcttgt ggcacaaaga aagattctaa aaaagaagaa
    50641 gttaaagaaa tcaaaatgtc tgacatcaaa gacgacgcag ttagcaaaaa aacaaaagtg
    50701 gttgatggcg aagaagttac agaatacacc acaaaagatg gaaacgtgat tcagattcct
    50761 gcaggaaacg aagaaggcat ggaatcaaaa gatgctggtg gatcaggcgc tcctgctaaa
    50821 aactaagggt tacaacaaag agcataaggt gactcgcaaa cgttacgcat gacatgaggc
    50881 agtctgccta agatggtaac tcacttatca taatgcctaa atagccaaac acactaactc
    50941 gcaaatgtac aaaatcatat acccgtgctt atgtgagcga acggttatat gatttttgtt
    51001 ttccaaaaac aagaaaagaa cgctaaaata gccagtttgt cgtgtttcaa gctaccaaaa
    51061 aggaagtgct aaaatgaaaa aaagatccat tatacctgtc atcttactgt tggtcatcgg
    51121 attaatcgtt ggtgttaagc gtcatcatga ctagtaggtc ttgctagtga ccgttcaaaa
    51181 gggataacgt tggtatggta taaccataaa aatcgtataa aaagaaaaaa tagctattga
    51241 ggagaaagta tgtttcagtt aagaaaaaaa atgacgcgca aacaattagc cttgttgagt
    51301 gctggagtgt tgacctgtgt ggttggtggt acctacttga taatgaatca tcaacaacaa
    51361 gaaattgtct ctagtgtcaa caaagtaaaa gccttaacca taaaagaagc catggaacaa
    51421 ggaaaagata tcagcttgac cttagctggc gaagtaacag ctaacaacag cagcaaagtc
    51481 aaaatcgact caagtaaagg agaagtcaaa gatgtctttg tcaaaaaagg cgatgttgtc
    51541 aaagtaggac aacccttgtt tagctatgaa acgtcacaac ggttaacggc tcaaagttca
    51601 gaatttgatg ttcaaaccaa agccaatcaa ctccaagttg ctaaaaccaa tgcagcattg
    51661 aagtgggaaa cctacaatcg caaggtcaat gaaatcaaca ccctaaaatc tcactacaac
    51721 tctgcaccag atgagagctt actagagcaa attcgcagcg cagaagacag tgtatcccaa
    51781 gcactaagcg atgccaaaac agcagatagc gatgtcaaag ccgctcaaat cgaactcgat
    51841 aaagctaatg ctactgccgc aacggaaaaa ggtaaactag agtatgacac cgttaagtca
    51901 gacaccgcag gaaccattgt tagcctaaat actgatttgc caaatcaatc aaaatccaaa
    51961 aaagaaaatg aaacttttat ggaaattatc gacaaatcaa aaatgttagt caaaggtaac
    52021 atcagtgaat ttgaccgtga caagttaaaa atcggtcaaa aagtcgaagt gattgaccgc
    52081 aaagacaact ctaaaaaatg gactggaaaa gtaacccaag ttggcaacct caaagcagag
    52141 gaaaaaggcc aaggtcaagg ccaaggtggc aatgaccaac aagataatcc aaaccaagca
    52201 aaattccctt atgttatcga acttgaccaa tcagacaagc agccactcat tggttcacac
    52261 acctatgtta atgtgctcaa caatgttcca gaagctggca agatcgtatt gaaagaaacc
    52321 tttacaatgg cagaaaatgg aaaaacctat gtgtggaaag ttgataaaaa caaggtcaaa
    52381 aaacaagaaa tcaagactaa gcccttctca aaaggttata ttgaggtgac aagtggcttg
    52441 actatgcaag ataagattgc tcagccgctt cctggcatga aagacggtat ggaggtagga
    52501 agtattgtta aaccttaaag atattcgaaa aagctatcat cttgggactg aagaatttgc
    52561 gattttaaaa ggaatcgatt tagaagttaa cgagggtgac tttttagcca tcatgggacc
    52621 atcaggttcg ggaaagtcaa cattgatgaa tatcattggg tgtttagata agcctggctc
    52681 tggctcatat gccattgaag gcagagacgt gtcatcctta tctgataatg aacttgctga
    52741 tttgcgcaat caaaaaatcg gctttgtttt tcaaaacttt aacctgatgc ccaagctaac
    52801 agcttgtcaa aatgtcgaat tgcccttgac ttatatgaat gttcctaaaa aagagcgtcg
    52861 caaacgagcc ctagagatgt taaagctcgt aggactagaa gaacgtagtg aatttaaacc
    52921 gatggagcta tctggtgggc aaaaacagcg tgtagcgatt gcaagagctt tagtcactaa
    52981 cccgagtttt atccttggtg atgagccaac aggtgcacta gacacaaaaa ccagcgtcca
    53041 aatcatggac ctatttaaac aattcaatga taacggcaaa acgattatta tcatcacaca
    53101 cgagcctgaa gtagctgcct tatgcaaaaa gacagtgatc ctaagagatg gtaatataga
    53161 acattccgat atagagtaaa gggggaaaat aatggaagat attattgcag ctttaggctc
    53221 tatattatca cacaagatgc ggtcaatttt gacaatgcta gggattatta tcggtattgg
    53281 tgccattatc gcaatctttt caatcatcga aggtaatacc gaaaatacca aaagacagtt
    53341 gattggtggc agcaataaca ctattaacat tgtgtttaac aaaaaaagca gtattgaccc
    53401 taaatttcca gacaagtcaa atgctaaaaa accagactat cttcctttta tggctgaaga
    53461 agagcttagc aaaatacagc aagtcaaagg cgtcaaaaac gccctgatct catatggtat
    53521 tgatgacaaa gtctaccatc taggccaaaa atcatctgca aagatttctg ccattacaaa
    53581 aaacgtagct gaagtgagac gcatgacatt tattaaaggc agtgactttt cagacaaaga
    53641 ctttattgac caaaaacagg tgatttacct tgaaaaaagc ttgtatgagt cactatttcc
    53701 aaaagacgat ggtcttggaa aatttgtcga agtgatggga aatcccttca gggtcattgg
    53761 agtgtttgaa tcaaaagaac aaagtggtct cacaagtggg actgagaaaa ttgcttatat
    53821 cccgctacat cagtggtata atattaatgg tgtagtggat gcgacacctg agatcacgat
    53881 ccagacctat cgcgcagatg acctcaaacc tgtggcaaag cgtgtcagtg atatgctcaa
    53941 tcaaacgatc cctaaatcag attatatgtt tggtgtcatg aaccttaaag aatttgaacg
    54001 ccaactagac aacctaaaca aatctaattt tgtgttatta gctggtattg ctagtatctc
    54061 tcttattgta ggtggtattg gtgtgatgaa cattatgcta gtatcagtta ccgaaagaac
    54121 gagagaaatt gggatcaaaa aagcgcttgg cgctagacgt aagcttattt taaaacaatt
    54181 tttaattgaa gcggtcattc taaccttgct aggtggtgtg ataggggtta tttcagggat
    54241 ggtatcagga ttgatcatca caagatcact cgagtatccc tatatcctat cgttgttctc
    54301 agttgtcttg agtttagcgt tttgttgtat tatagggatt gtctttggac tattaccagc
    54361 cattaaagcg tctaagctag acccaattga agcattgcga tttgaataat caaccaaaca
    54421 agcataaaag tcaaaaagga tgaccctttg atgtcatcct tagctgcttg atacactaaa
    54481 cgccaatcta gaaagggaag ttatgtttaa aatattagta gttgaagatg atgataccat
    54541 cagtcaagtg atttgtgagt ttttaaaagc gaataactat gatccagatt gtgtgtttga
    54601 tggccaagct gccttagaca agtggcagac aacgtcttat gatctgatta ttttagacat
    54661 catgctccct tccttaagcg gcttagaagt gctaaaaaca attcgaaaga catcagatgt
    54721 ccctattatt atgctaacgg cattagatga cgagtacaca cagcttgtaa gcttcaacca
    54781 tttgattagt gattatgtga ccaaaccatt ttcaccactc attttaatca aacgtatcga
    54841 aaatgtatta cgcgtctcta ctccagatga aaagcgccaa atcggagact tacttgttga
    54901 tgagaccgaa catagcgtct attggcaagg aacattggtc aaactaacca aaaaagaata
    54961 tgacattatt gattatttag caaaacgtca ccaaaagatt gtcaccagag accaattgat
    55021 ggatgacata tggggctatt ctgaactgga cacgcgtgtc cttgacaacc acatcaagaa
    55081 ccttcgtaaa aaaatgacgg gtattcccct caagacaatt acaggcatgg gatatttatt
    55141 gggagagcgt gagtgagact aatcaaaaaa acctttttgg tcatcaatgg cttaattatt
    55201 gtagtggtta cctctatttt gttagtgctt tattttgcaa tgccaattta ttacaccaaa
    55261 gtcaaagaca aagaagttaa gcgtgaattt gaccaaacaa gcaagcaaat caaaggcaaa
    55321 acggtaaccg agattagaga tatcctaaca aaaaaaatca acaaagataa tatttggtac
    55381 agcttagtag acagtgataa ccaactgctc tatccttcct tgcagctgtt agacggcgtc
    55441 agtgaaagca aagacagtca aaatgttaat atcgtcacca cctttgacaa ctcttattct
    55501 aatgttaagg tgatgagtca aaaagtaacc ctacgcgatg gaaaaaagat gacattgctt
    55561 gggcaatctt cacttcaacc cgtaacagat gctagcaaag ttctccttga cctctacccg
    55621 tcactattga ttttttcagt gaccgtaggg agtattgtcg cctacttata tagtaggact
    55681 tctagccggc gtatccttag catgtcacaa actgccaaaa aaatggtcaa cctagaacca
    55741 aacttaacgt gtaccattca cggcaaagat gaaatagcaa tgttggctag tgatattaac
    55801 cgtttgtatg cgagtctttc aacgagcatc aaatccttgc aaaaagagta tgaaaaagct
    55861 tctgattcag aaagagagaa atctgagttt ttacgcatga catcgcacga gctaaagaca
    55921 ccaatcacca gtgttatcgg aatgattgat ggaatgctct ataatgttgg tgactttgca
    55981 gatcgtgaca aatatttgcg aaaatgccga gacgtccttg aagggcaagc ccaactggtt
    56041 caatccattt tatctttatc taagattgaa accctagctt ctcaaaatca agaactgttt
    56101 tcactaaaaa gcagcctaga agaagaaatg gaagtctttc tcgtcttatc agaactaaaa
    56161 catctcaaag tgactatcaa tctcgaagaa caattcgtca aagccaataa agtatatcta
    56221 ctaaaggcga ttaaaaatat tattgacaat gcctttcact ataccaaatc aggcggccaa
    56281 gtgatgattc aactaaaaga caaccaacta gtgattaaaa atgaagcaga gacattattg
    56341 acacaacagc agatgaaaca gttattccaa ccgttttatc gaccagatta tagtcgtaac
    56401 aggaaagacg gtggtacagg attggggctg tttatcaccc accagattct tgatcagcat
    56461 catctggctt atcgctttgt tgttcttgat caaagatgga tggtatttac gattgatttt
    56521 ccatcccatc atgacgattg atccacacta gtaggacgac aaaagccatc aatcactaac
    56581 caagccttga cctttaccta tcattgttta ggcaagtata aaaaagagga gagaaatcat
    56641 atatgaagaa aaggaaattg ttagcagtaa cactattaag taccatactc ttaaacagtg
    56701 cagcgccatt agttgttgct gacacctcct tgcgtaataa cacatcatcc actgatcagc
    56761 ctactacagc agatactgat acggatgacg agagtgaaac agcaaaaaaa gacaaaaaaa
    56821 gcaaggaaac agcgtcgcag cacgacaccc aaaaagacca taagccatca tacaatcacc
    56881 caacccctcc ttcaaatgat actaagcaga ccgatcaggc atcatctgaa gctactgaca
    56941 aaccaaataa agacaaaaac gacaccaagc aaccagacag cagtgatcaa tccaccccat
    57001 ctcccaaaga ccagtcgtct caaaaagagt cacaaaacaa agatggccga cctaccccat
    57061 cacctgatca gcaaaaagat cagacacctg ataaaacccc tgaaaaagga ccagaaaaag
    57121 cagctgaaaa aaccccagag ccaaatcgtg acgctccaaa acccatccaa cctcctttag
    57181 gagcagcagc tcctgtcttt gcaccgtgga gagaaagtga caaagacctg agcaagctaa
    57241 aaccaagcag tcgctcatca gcggcttacg tgagacactg gacaggtgac tctgcctaca
    57301 ctcacaacct gttgtcacgc cgttatggga ttactgctga acagctagat ggttttttga
    57361 acagtctagg tattcactat gataaagaac gcttaaacgg gaagcgttta ttagaatggg
    57421 aaaaactaac aggactagac gttcgagcta tcgtagctat tgcaatggca gaaagctcac
    57481 taggtactca gggagttgct aaagaaaaag gatccaatat gtttggttat ggcgcctttg
    57541 acttcaaccc aaacaatgcc aaaaaataca gcgatgaagt tgctattcgt catatggtag
    57601 aagacactat cattgccaac aaaaaccaaa cctttgaaag acaagacctc aaagcaaaaa
    57661 aatggtcact aggccagttg gataccttga ttgatggtgg ggtttacttt acagatacaa
    57721 gtggcagtgg gcaaagacga gcagatatca tgaccaaact agaccaatgg atagatgacc
    57781 atggaaacac acctgatatt ccagaacatc tcaagataac ttccgggaca caatttagcg
    57841 aagtgcccgt aggttataaa agaagtcagc cacaaaacgt tttgacctac aagtcagaga
    57901 cctatagctt tggccaatgc acctggtacg cctataatcg tgtcaaagag ctaggttatc
    57961 aagtcgacag gtacatgggt aacggtggcg actggcagcg caagccaggc tttgtgacca
    58021 cccataaacc taaagttggc tatgtcgtct catttgcacc aggccaagca ggagcagatg
    58081 caacctatgg ccacgtcgct gttgtagagc aaatcaaaga agatggttcc atcttgattt
    58141 cagagtcaaa tgttatggga ctaggcacca tttcctatcg gacgttcaca gctgagcagg
    58201 ctagtttgtt gacctatgtc gtaggggaca aactcccacg accataaata aacaacaaga
    58261 cgctacctgc ctgttgacca atctcaaaaa gagatagcgt caacttagaa tgaggttcat
    58321 cagatgataa agagagtgac caccccgagt caaaaaacaa aaaaacgtgt tcgtaatggc
    58381 tacctcctaa aactaggtac agcctgttta ctcttaagta tactaagtta tgccattggt
    58441 cttttgggcc agcctagcat ggaaaatacg tttatgggaa tagcgaatgt tgccatgtta
    58501 ggaagtgtct gtttctttat tatctttgct ctaaaccgta tctttgacgc actagaggac
    58561 aatctgcgag attagagtaa taggtcacat aatcttccaa taatttagag cacaagctaa
    58621 gttattggaa gtttttttgt cttttgagag ccatgatgcc atcaaaaagc taaatactcc
    58681 ttatgatgtg agagccacat ggctaaaatt aaaagcaaaa tagaccccaa attcccgttt
    58741 tctcagaata gccaacgaaa aaagataagt taaccagttc acaaaaaaac gtcttagaaa
    58801 cgttttcaag agctaatatt ggagtaaatt gactgaagta tgatagaatt tttaatggtt
    58861 gtaccataac agtcaaactt aaaaactgaa atcagacaaa aacattaaat tgcatgtaaa
    58921 aaacctaatt aagttagtga caaaagataa attaggttca aaaaatataa aaaaaatata
    58981 aattaagacc tcttttaaaa taaaaagagc ataaatggca taaaaaatgg gtaaaaatcc
    59041 aatttttggg tcacatttta taatatgttt tataaataat gaacaaaaag gaataattgc
    59101 gtgatcgtga ctgttttttg gattttaatg aaagaatttg aaaggtattt tatggtatac
    59161 tttttcttga tataggtctt actgacttaa cgaaatgcct cacgaaataa caagaaaaat
    59221 taaaaagaag ggtatacaag gtaatgtatg taagtaagtt gtttacaagt caacagtgga
    59281 gagaactaaa attaatctca tacgtaacag aaaacgctga tgccattggc gttaaagata
    59341 aagaactcag caaagctctc aacatctcca tgttaacatt gcaaacatgt ctcactaaca
    59401 tgcaatttat gaaggaagtg ggaggaatta cctataaaaa tggttatatt acaatctggt
    59461 accatcaaca ttgcggtttg caagaagtct atcaaaaagc tctgagacac tctcaatcat
    59521 ttaaattact ggagaccctt tttttccgag acttcaactc tttggaagaa ttagctgaag
    59581 agctctttgt gagcctttca acactcaagc gtctcatcaa aaaaaccaac gcctatttga
    59641 cgcatacttt tggtattact attttaacta gtcccgtaca agtatcagga gatgaacacc
    59701 agattcgact attttacctc aaatattttt cggaagccta taaaatctca gagtggcctt
    59761 ttggagaaat cctaaactta aagaactgtg agcggctact cagtctaatg ataaaagagg
    59821 tcgatgtgag ggttaatttt acgttatttc agcaccttaa aatactaagc tcagttaact
    59881 tgattcgcta ttacaaggga tactctgccg tctacgacaa caaaaaaacc agtcaccgtt
    59941 tttctcagct catccaatca tccttagaaa cccaagacct ttcacgctta ttttacctca
    60001 aatttggact atacctagat gagactacca tagctgagat gttttctaat cacgttaatg
    60061 accaattaga aatcggttat gcgtttgata gcatcaagca agactcgcca acgggctgtc
    60121 gaaaagtgac caactggatt catcttcttg atgagttaga aattaacctc aatctcagcg
    60181 tcaccaacaa atatgaagta gctgtcatcc ttcataacac taccgttttg aaagaagaag
    60241 atatcaccgc taattaccta tttttcgatt acaaaaaaag ttacctcaac ttttacaagc
    60301 aagaacaccc tcatctttat aaagcatttg tagcaggtgt agaaaaactg atgcgttcag
    60361 agaaagaacc tatcagcaca gagttgacta accaattgat ctacgccttt ttcatcactt
    60421 gggaaaatag tttcctaaaa gtaaatcaaa aagatgaaaa aattcgtctt ctggtgattg
    60481 aaagaagttt taatagtgtt ggtaatttcc taaaaaagta catcggagag ttttttagca
    60541 tcacaaactt caatgagcta gatgctctga ccatcgatct agaagagatt gaaaaacagt
    60601 atgatgtgat cgtgacagat gttatggtag gaaaaagcga tgagttagaa attttctttt
    60661 tctacaaaat gattccagaa gcgattattg acaagctcaa tgtgttttta aacatcagct
    60721 ttgcagacag cttgccacta gacaaaccca tcaagaaccc cttggacttt catcgcaaag
    60781 agcttacctt acccactccc cccaacaagt tgcacgcccc cccctccaca acttagacag
    60841 cctagccgca gaaactcaaa aacagattca tcattaatag catttaggtc aaaaaggtgg
    60901 caaaagctaa aaaagctggt ctttaccttt tggcttttat tatttacaat agaattatta
    60961 gagttaaacc ctgaaaatga gggtttttcc taaaaaatga taacataagg agcataaaaa
    61021 tggctaaaaa taacacgaat agacactatt cgcttagaaa attaaaaaaa ggtactgcat
    61081 cagtagcagt ggctttgagt gtaatagggg caggattagt tgtcaatact aatgaagtta
    61141 gtgcaagagt gtttcctagg gggacggtag aagacccgga caaagcacga gaacttctta
    61201 acaagtatga cgtagagaac tctatgttac aagctaataa tgacaagtta acagatcaga
    61261 ataaaaactt aacagatcag aataaggagt taaaagctga ggagaatagg ttaacaactg
    61321 agaataaagg gttaactaaa aagttgagtg aagctgaaga agaagcagca aataaagagc
    61381 aagaaagtaa agaaaccatt ggtaccctta aaaaaatctt ggatgagaca gtaaaagata
    61441 aaattgctaa ggagcaagaa agtaaagaaa ccattggtac ccttaaaaaa accttggatg
    61501 agacagtaaa agataaaatt gctaaggagc aagaaagtaa agaaaccatt ggtaccctta
    61561 aaaaaatctt ggatgagaca gtaaaagata aaattgcgag agagcaaaaa agtaaacaag
    61621 acattggtgc ccttaaacaa gaattagcta aaaaagatga aggaaacaaa gtttcagaag
    61681 caagccgtaa gggtcttcgc cgtgacttgg acgcatcacg tgaagctaag aaacaggttg
    61741 aaaaagattt agcaaacttg actgctgaac ttgataaggt taaagaagaa aaacaaatct
    61801 cagacgcaag ccgtcaaggt cttcgccgtg acttggacgc atcacgtgaa gctaagaaac
    61861 aagttgaaaa agctttagaa gaagcaaaca gcaaattagc tgctcttgaa aaacttaaca
    61921 aagagcttga agaaagcaag aaattaacag aaaaagaaaa agctgagcta caagcaaaac
    61981 ttgaagcaga agcaaaagca ctcaaagaac aattagcgaa acaagctgaa gaacttgcaa
    62041 aactaagagc tggaaaagca tcagactcac aaacccctga tgcaaaacca ggaaacaaag
    62101 ttgttccagg taaaggtcaa gcaccacaag caggtacaaa acctaaccaa aacaaagcac
    62161 caatgaagga aactaagaga cagttaccat caacaggtga aacagctaac ccattcttca
    62221 cagcggcagc ccttactgtt atggcaacag ctggagtagc agcagttgta aaacgcaaag
    62281 aagaaaacta agctatcact ttgtaatact gagtgaacat caagagagaa ccagtcggtt
    62341 ctctctttta tgtatagaag aatgagatta aggaggtcac aaactaaaca actcttaaaa
    62401 agctgacctt tactaataat cgtctttttt ttataataaa gatgttaata atataattga
    62461 taaatgagat acatttaatc attatgacaa aagcaagaaa aatagctgta tcatatgcaa
    62521 ataacccctg tttgctcttt aaaaagacgt tatccttatt tctctacgca cagatggaca
    62581 gctaggagag aatcgtttga ttctctcttt tcttaatggt cataaagaca aagtctctca
    62641 tcatgaaagg acaacacatt gcgtaaaaaa caaaaactac catttgacaa acttgccatt
    62701 gcgcttatgt ctacgagcat cttgctcaat gcacaatcag acattaaagc aaatactgtg
    62761 acagaagaca ctcctgctac cgaacaagcc gtagaaaccc cacaaccaac agcggtttct
    62821 gaggaagcac catcatcaaa ggaaaccaaa accccacaaa ctcctgatga cgcagaagaa
    62881 acagtagcag ataaggctaa tgatctagcc cctcaagctc ctgctaaaac tactgatacg
    62941 ccagcaacct caaaagcgac tattagggat ttgaacgacc cttctcaggt caaaaccctg
    63001 caggaaaaag caggcaaagg agctgggact gttgttgcag tgattgatgc tggttttgat
    63061 aaaaatcatg aagcatggcg cttaacagac aaaactaaag cacgttacca atcaaaagaa
    63121 gatcttgaaa aagc
//
LOCUS       DAXMQE010000008        61560 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.008, whole genome shotgun sequence.
ACCESSION   DAXMQE010000008 DAXMQE010000000
VERSION     DAXMQE010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 61560)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 61560)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..61560
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.008"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            288..1169
                     /locus_tag="ACF4ZO_000537"
     CDS             288..1169
                     /locus_tag="ACF4ZO_000537"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004332 - fructose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase"
                     /protein_id="HFD5486109.1"
                     /translation="MAIVSAEKFVQAARENGYAVGGFNTNNLEWTQAILRAAEAKQAP
                     VLIQTSMGAAKYMGGYKVCQSLITNLVESMGITVPVAIHLDHGHYGDALECIEVGYTS
                     IMFDGSHLPVEENLAKTAEVVKIAHAKGVSVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPENWEGLALDHLEKLTAAVPGFPIVLHGGSGIPDDQI
                     KEAIRLGVAKVNVNTESQIAFSNATREFARNYEANEAEYDGKKLFDPRKFLAPGMKAV
                     QGAVEERIDVFGSANKA"
     gene            1551..1739
                     /gene="rpmB"
                     /locus_tag="ACF4ZO_000538"
     CDS             1551..1739
                     /gene="rpmB"
                     /locus_tag="ACF4ZO_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HFD5486110.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRTVKPNLQKVTILVDGKP
                     KKVWASARALKSGKVERI"
     gene            1891..2256
                     /locus_tag="ACF4ZO_000539"
     CDS             1891..2256
                     /locus_tag="ACF4ZO_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HFD5486111.1"
                     /translation="MTVKINTKDGLIELSDDVIATVVGGSATEIFGVVGMASKSAIKD
                     NFQSLLRKENYAKGVVVKSTDLGISVDVYTVMSYGVKISEVSKNIQERVKFNLESQLG
                     LTADMVNVYVQNIKVVGEN"
     gene            2256..3920
                     /locus_tag="ACF4ZO_000540"
     CDS             2256..3920
                     /locus_tag="ACF4ZO_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HFD5486112.1"
                     /translation="MSNITTSLFQEMVQAAATRLGKQAEYVNSLNVFPVPDGDTGTNM
                     SMTMDNGAKEVADKPASTVGEVGQMLSKGLLMGARGNSGVITSQLFRGFGQSIKGKDE
                     LTGKDLAQAFQVGVEVAYKAVMKPVEGTILTVSRGAATAALKKADLTDDAVEVMQAAL
                     DGAKGALAKTPDLLPVLKEVGVVDSGGQGLVFIYEGFLSALNGDYVTSADFKATPANM
                     SEMINAEHHKSVVGHVATEDITYGYCTEIMVALKQGPTYVKEFNYDEFQGYLSGLGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLIKIKVDNMRNQHEAQVQKTDVEKNKA
                     EVKDFGLIAVVAGEGLSEIFKAQGVDYVISGGQTMNPSTEDIVKAIEAVNAKQVIILP
                     NNKNIFMAAQSAAEVVDIPAAVVATRTVPQGFTSLLAFDPSKSLEDNVADMSTSLSDV
                     VSGSVTLAVRDTTIDGLEIHENDFLGMVDGKIIVSNPDMEVTLKAAFAKMIDEDSEIV
                     TIFVGEEGDQDLAEELAGYLGETYEDVEVEIHQGDQPVYPYLMSVE"
     gene            4158..5048
                     /locus_tag="ACF4ZO_000541"
     CDS             4158..5048
                     /locus_tag="ACF4ZO_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HFD5486113.1"
                     /translation="MLGPFIFIAFGVIVILAIVASTLYVVRQQSVAIVERFGRYQKTA
                     TSGIHVRLPFGIDKIAARVQLRLLQSEIIVETKTKDNVFVTLNVATQYRVNEQNVTDA
                     YYKLMKPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMSTYGYIIV
                     KTLITKVEPDAEVKQSMNEINAAQRKRVAAQELANADKIKIVTAAEAEAEKDRLHGVG
                     IAQQRKAIVDGLAESIQELKEANISLNEEQIMSILLTNQYLDTLNTFAAKGNQTLFLP
                     NTPSGVEDIRTQVLSALKTK"
     gene            5278..6132
                     /locus_tag="ACF4ZO_000542"
     CDS             5278..6132
                     /locus_tag="ACF4ZO_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5'-nucleotidase, lipoprotein e(P4) family"
                     /protein_id="HFD5486114.1"
                     /translation="MKSKKVVSVISLTLSLFLVTGCAKVDNNKSVNRKPATKQTYNSY
                     SDDQLRSRENTMSVLWYQRAAETQALYLQGYQLATDRLKEQLNKPTDKPYSIVLDIDE
                     TVLDNSPYQAKNVLEGTGFTPESWDYWVQKKEAKPVAGAKDFLQFADQNGVQIYYISD
                     RSTTQVDATMENLQKEGIPVQGRDHLLFLEKGVKSKESRRQKVKETTNVTMLFGDNLL
                     DFADFSKKSQEDRTALLSDLQEEFGRRFIIFPNPMYGSWEGAIYKGEKLDVLKQLEER
                     RKSLKSFK"
     gene            6325..7521
                     /gene="pgk"
                     /locus_tag="ACF4ZO_000543"
     CDS             6325..7521
                     /gene="pgk"
                     /locus_tag="ACF4ZO_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004618 - phosphoglycerate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HFD5486115.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKEGKSLAPVAADLAAKLGQDVVFPGVTRGSKLEE
                     AINALEDGQVLLVENTRFEDVDGKKESKNDEELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKDLLEKSNGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAEFDQALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            7784..8335
                     /locus_tag="ACF4ZO_000544"
     CDS             7784..8335
                     /locus_tag="ACF4ZO_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HFD5486116.1"
                     /translation="MKTLRKLLSNYKFDIKKFKLGMRTLKTGLSVFLVLLVFHLFGWK
                     GLQIGALTAVFSLREDFDKSVHFGFSRIIGNSIGGLLSLVFFAFNEIFHQAFWVTLLI
                     VPICTMLCIMVNVACNNKSGIIGAVAALLIITLSIPTGQTFIYVTSRVFETFCGVFVA
                     ILVNTDVELIKNKWFNKKHSDVR"
     gene            8402..8773
                     /locus_tag="ACF4ZO_000545"
     CDS             8402..8773
                     /locus_tag="ACF4ZO_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFD5486117.1"
                     /translation="MKEKELRRSMAVFPIGTVMTLTDLSARQIRYYEDQGLIKPERTQ
                     GNRRMFSLNDMDRLLEIKDFLSEGLNIAAIKREYVERQGKLMQKQKALTDADVRRILH
                     DEMLTQSGFSTPSQHIGNFRI"
     gene            8811..10157
                     /gene="glnA"
                     /locus_tag="ACF4ZO_000546"
     CDS             8811..10157
                     /gene="glnA"
                     /locus_tag="ACF4ZO_000546"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004356 - glutamine synthetase activity
                     [Evidence IEA];
                     GO_process: GO:0006542 - glutamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HFD5486118.1"
                     /translation="MAITVADIRREVKEKNVTFLRLMFTDIMGVMKNVEIPATKEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWIIFPWGDENGAVAGLICDIYTAEG
                     KPFAGDPRGNLKRALKHMNEIGYKSFNLGPEPEFFLFKMDDKGNPTLEVNDNGGYFDL
                     APIDLADNTRREIVNILTKMGFEVEASHHEVAVGQHEIDFKYADVLKACDNIQIFKLV
                     VKTIAREHGLYATFMAKPKFGIAGSGMHCNMSLFDNQGNNAFYDETDKRGMQLSEDAY
                     YFLGGLMKHAYNYTAITNPTVNSYKRLVPGYEAPVYVAWAGSNRSPLIRVPASRGMGT
                     RLELRSVDPTANPYLALAVLLEAGLDGIINKIEAPEPVEANIYTMTMEERNEAGIIDL
                     PSTLHNALKALQKDDVVQKALGYHIYTNFLEAKRIEWSSYATFVSQWEIDHYIHNY"
     gene            complement(10385..12067)
                     /gene="rnjA"
                     /locus_tag="ACF4ZO_000547"
     CDS             complement(10385..12067)
                     /gene="rnjA"
                     /locus_tag="ACF4ZO_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004534 - 5'-3' RNA exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J1"
                     /protein_id="HFD5486119.1"
                     /translation="MTNISLKPNEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKF
                     PEDDLLGIDYVIPDYSYIVDNLDRVKALVITHGHEDHIGGIPFLLKQANIPIYAGPLA
                     LALIRGKLEEHGLWREATVYEINHNTELTFKNMSVTFFKTTHSIPEPVGIVIHTPQGK
                     IICTGDFKFDFTPVGDPADLQRMAALGEEGVLCLLSDSTNAEIPTFTNSEKVVGQSIL
                     KIIEGIHGRIIFASFASNIYRLQQAAEAAVKTGRKIAVFGRSMEKAIVNGIELGYIKV
                     PKGTFIEPSELKNLHASEVLIMCTGSQGESMAALARIANGTHRQVTLQPGDTVIFSSS
                     PIPGNTTSVNKLINTIQEAGVDVIHGKVNNIHTSGHGGQQEQKLMLSLIKPKYFMPVH
                     GEYRMQKVHAGLAMDIGIPKENIFIMENGDVLALTSDSARIAGHFNAQDIYVDGNGIG
                     DIGAAVLRDRRDLSEDGVVLAVATVDFNTQMILAGPDILSRGFIYMRESGDLIRESQR
                     VLFNAIRIALKNKDASIQSVNGAIVNALRPFLYEKTEREPIIIPMVLTPDKH"
     gene            complement(12069..12299)
                     /locus_tag="ACF4ZO_000548"
     CDS             complement(12069..12299)
                     /locus_tag="ACF4ZO_000548"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase subunit epsilon"
                     /protein_id="HFD5486120.1"
                     /translation="MIYKVFYQETKDQSPRRESTKALYLNIDATDELDGRIKARRLVE
                     DNTYYNVEFIELLSDKHLDYEKETGVFELTEF"
     gene            12581..13279
                     /gene="tsaB"
                     /locus_tag="ACF4ZO_000549"
     CDS             12581..13279
                     /gene="tsaB"
                     /locus_tag="ACF4ZO_000549"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HFD5486121.1"
                     /translation="MKTLAFDTSNKTLSLAILDDETLLADMTLNIQKNHSVSLMPAID
                     FLMTCTDLKPQDLERIVVAKGPGSYTGLRVAVATAKTLAYSLNIALVGISSLYALAAS
                     TCKQYPNTLVVPLIDARRQNAYVGYYRQGKSVMPQAHAPLEVIIEQLVEEGQLIFVGE
                     TAPFAEQIQKKLPQAILLPTLPSAYECGLLGQSLAPENVDAFVPQYLKRVEAEENWLK
                     DNEIKDDSHYVKRI"
     gene            13281..13706
                     /gene="rimI"
                     /locus_tag="ACF4ZO_000550"
     CDS             13281..13706
                     /gene="rimI"
                     /locus_tag="ACF4ZO_000550"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008999 -
                     peptide-alanine-alpha-N-acetyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HFD5486122.1"
                     /translation="MKTVEEQAKKIYQLLEMVYGTSPWTLEQVLIDIRRDQTDYFLLY
                     DYDKLLGFLAIQDLSGEVEMTQIAILPSHQGLGLASQLMTHLGSIESDIFLEVRESNH
                     RAQGLYQKFGFKFIGKRPDYYRNPIETALLMKREGKHDR"
     gene            13696..14724
                     /gene="tsaD"
                     /locus_tag="ACF4ZO_000551"
     CDS             13696..14724
                     /gene="tsaD"
                     /locus_tag="ACF4ZO_000551"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HFD5486123.1"
                     /translation="MTDRYILAVESSCDETSVAILKNESTLLSNVIASQVESHKRFGG
                     VVPEVASRHHVEVITTCFEDALQEAGISASDLSAVAVTYGPGLVGALLVGLAAAKAFA
                     WANHLPLIPVNHMAGHLMAAREQEPLVYPLIALLVSGGHTELVYVPEPGDYHIIGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDQLAHKGQDTYHFPRAMITEDHLEFSFSGLKSA
                     FINLHHNAKQKGNELILEDLCASFQAAVLDILLAKTKKALSRYPAKMLVVAGGVAANQ
                     GLRDRLAQEITHIEVVIPKLRLCGDNAGMIALAAAIEYDKQHFANMSLNAKPSLAFDQ
                     FPDSFVIN"
     gene            complement(14895..15164)
                     /gene="rpsN"
                     /locus_tag="ACF4ZO_000552"
     CDS             complement(14895..15164)
                     /gene="rpsN"
                     /locus_tag="ACF4ZO_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HFD5486124.1"
                     /translation="MAKKSKIAKYQKQLQLIEQYADLRRDLKAKGDYESLRKLPRDSN
                     PNRLKNRDKIDGRPHAYMRKFGVSRINFRDLAHKGQLPGVTKASW"
     gene            complement(15384..16142)
                     /locus_tag="ACF4ZO_000553"
     CDS             complement(15384..16142)
                     /locus_tag="ACF4ZO_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFD5486125.1"
                     /translation="MSTNDLTKKLKKLKHVQVYNTIFQLIQDGTYSPGMQLPSEPELA
                     RQLNVSRMTLRKSLALLQEDHLIKNIRGKGNFILKTPETKYHQGFEYLQHPIYASLSS
                     DITKVELEYRIEVPTVAITASLKQETPVVIIVDRWYHSQNKAIAYSLSFIPIEVISKY
                     AINLNQEEPLLTFLEEKIYDSGKASHSCNQIGYTKTGNYTATKYTLSENSAFILIQET
                     LYNGKDILVSTKHYVPADLFDLKVQSQSCQSDTH"
     gene            16382..17161
                     /gene="udp"
                     /locus_tag="ACF4ZO_000554"
     CDS             16382..17161
                     /gene="udp"
                     /locus_tag="ACF4ZO_000554"
                     /EC_number="2.4.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uridine phosphorylase"
                     /protein_id="HFD5486126.1"
                     /translation="MQNYSGEVGLQYHLQIRPGDVGRYVIMPGDPKRCAKIAEHFDNA
                     VLVADSREYVTYTGTLNGEKVSVTSTGIGGPSASIAMEELKLCGADTFIRVGTCGGIE
                     LDVKGGDIVIATGAIRMEGTSKEYAPIEFPAVADLEVTNALVNAAKKLGYTSHAGVVQ
                     CKDAFYGQHEPERMPVSYELLNKWEAWKRLGTKASEMESAALFVAASHLGVRCGSDFL
                     VVGNQERNALGMDNPMAHDTEAAIQVAVEALRTLIENDKSQ"
     gene            17182..18384
                     /locus_tag="ACF4ZO_000555"
     CDS             17182..18384
                     /locus_tag="ACF4ZO_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0005337 - nucleoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:1901642 - nucleoside transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HFD5486127.1"
                     /translation="MQFIYSIIGILLVLGIVYAISFNRKSVSLSLIGKALIVQFIIAL
                     ILVRIPLGQQIVSVVSTGVTSVINCGQAGLNFVFGSLADSGAKTGFIFAIQTLGNIVF
                     LSALVSLLYYVGILGFVVKWIGKGVGKIMKSSEVESFVAVANMFLGQTDSPILVSKYL
                     GRMTDSEIMVVLVSGMGSMSVSILGGYIALGIPMEYLLIASTMVPIGSILIAKILLPQ
                     TEPVQKIDDIKMDNKGNNANVIDAIAEGASTGAQMAFSIGASLIAFVGLVSLINMMLS
                     GLGIRLEQIFSYVFAPFGFLMGFDHKNILLEGNLLGSKLILNEFVSFQQLGHLIKSLD
                     YRTALVATISLCGFANLSSLGICVSGIAVLCPEKRSTLARLVFRAMIGGIAVSMLSAF
                     IVGIVTLF"
     gene            18414..19085
                     /gene="deoC"
                     /locus_tag="ACF4ZO_000556"
     CDS             18414..19085
                     /gene="deoC"
                     /locus_tag="ACF4ZO_000556"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004139 - deoxyribose-phosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0009264 - deoxyribonucleotide catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HFD5486128.1"
                     /translation="MEVKDILKTVDHTLLATTATWPEIQTILDDAMAYETASACIPAS
                     YVKKAAEYVSGKLAICTVIGFPNGYSTTAAKVFECQDAIQNGADEIDMVINLTDVKNG
                     DFDTVEEEIRQIKAKCQDHILKVIVETCQLTKEELIELCGVVTRSGADFIKTSTGFST
                     AGATFEDVEVMAKYVGEGVKIKAAGGISSLEDAKTFIALGASRLGTSRIIKIVKNEAT
                     KPDSY"
     gene            complement(19180..20349)
                     /locus_tag="ACF4ZO_000557"
     CDS             complement(19180..20349)
                     /locus_tag="ACF4ZO_000557"
                     /EC_number="1.14.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HFD5486129.1"
                     /translation="MTQYDTIIIGGGPAGMMAAISSSYYGYKTLLIEKNRRLGKKLAG
                     TGGGRCNVTNSGNLDVLMAGIPGNGRFLYSVFSQFDNHDIIAFFEENGVKLKEEDHGR
                     MFPTTDKSRTIIDALEKKIKALGGQVLTSTEVVSVKKQDDLFYLKSADQTFTCQKLIV
                     TTGGKSYPSTGSTGFGHDIARHFKLTVTDLEAAESPLLTDFPHKVLQGISLDDVTLSY
                     DKHVITHDLLFTHFGLSGPAALRLSSFVKGGEIAELDFLPHLSTDDLTAYLSDQRDKN
                     IKNALKGLLPERVADFLSEDYPEKVKQLSPKQEKELLDKLKHLQIPITGKMSLAKSFV
                     TKGGVDLKEINPKTLESKKVPGLYFAGEVLDINAHTGGFNITSALCSGWIAGKSS"
     gene            20555..21085
                     /locus_tag="ACF4ZO_000558"
     CDS             20555..21085
                     /locus_tag="ACF4ZO_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HFD5486130.1"
                     /translation="MGIEKTVSELADILGVSRQAVNNRVKSLPEEDLDKNEKGVTVVK
                     RSGLVKLEEIYKKTIFDDEPISEETKQRELLEILVDEKNTEITRLYEQLKAKDAQLAS
                     KDEQMRVKDVQIAEKDKQLDQQQQLTAKAMADKETLKLELEEAKAEANQARLQVEEVQ
                     AEVGPKKGFLTRLFAK"
     gene            21134..21721
                     /locus_tag="ACF4ZO_000559"
     CDS             21134..21721
                     /locus_tag="ACF4ZO_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HFD5486131.1"
                     /translation="MKHLDTYIAFDLEFNTVNDVSHIIQVSAVKYDHHKEVDSFDTYV
                     YTDVPLQSFINGLTGITSDKIAAAPKVEEVMAAFKNFVGELPLIGYNAQKSDLPILAE
                     NGLDLRDQYQIDLFDEAYDRRSADLNGIANLRLQTVATFLGIKGRGHNSLEDARMTAA
                     IYKSFLETDTNKAYLSQQEEVTTDTPFAALGDFFD"
     gene            21873..22610
                     /locus_tag="ACF4ZO_000560"
     CDS             21873..22610
                     /locus_tag="ACF4ZO_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFD5486132.1"
                     /translation="MSQFYSTGELANLAGVSIRTVQYYDQRGILIPTALTAGGRRLYT
                     DSDLEQLRMICFLRDLGFSIEQIRKVLAEENAAQVLELLLVDHIATAKEDLAAKEQQV
                     DIAVKILDRLRKQDPQSLDFLMDISLSMKNQKAWKKLQWKMGISIFLAIVSYVGLILL
                     SNYLQKFWLVYVAMGLFLPGFSWLVIYFRKQFIYLCPHCHQKFEPSFNEFALAGHTPR
                     TRKLTCSHCHQKSYCLELAKEDTVSRG"
     gene            complement(22667..22966)
                     /locus_tag="ACF4ZO_000561"
     CDS             complement(22667..22966)
                     /locus_tag="ACF4ZO_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016503193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HFD5486133.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQKQADLAAMQFTGKSAQDLVTATFT
                     GDKKLVGIDFKEAVVDPEDVETLQDMTTQAINDALTQIDEATKKTLGAFAGKLPF"
     gene            complement(23159..23533)
                     /locus_tag="ACF4ZO_000562"
     CDS             complement(23159..23533)
                     /locus_tag="ACF4ZO_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFD5486134.1"
                     /translation="MSAKKTFFASNLKYLRLKKNMEQLELANLLGRKSSSSISEWEKG
                     KYTPKSGLLSDIAAIFDVSLTALMEEDLTLENKGVSYQLPQRELAMISEQLSENNYTK
                     WVDFAQILLEQQAKEDRELDNH"
     gene            23703..23924
                     /locus_tag="ACF4ZO_000563"
     CDS             23703..23924
                     /locus_tag="ACF4ZO_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFD5486135.1"
                     /translation="MTKSTLKELRTTKKMTQQELSHLTGISVRTIARYEKDTKKLRRA
                     KYEKLKGIAQALAVSVDDIFLGIDSEFMN"
     gene            complement(24004..26286)
                     /locus_tag="ACF4ZO_000564"
     CDS             complement(24004..26286)
                     /locus_tag="ACF4ZO_000564"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008239 - dipeptidyl-peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HFD5486136.1"
                     /translation="MRYNQFSYIPTSLERAAEELKELGFDLDLQKTAKANLESFLRKL
                     FFHYPDSDYPLSHLIAKNDMDALSFFQSEQELSKEVFDLLALQVLGFIPGVDFTEADA
                     FLDKLAFPIHFDETEIIKHIHHLLATRCKSGMTLIDDLVSQGMLTMDNDYHFFNGKSL
                     ATFDTSQLIREVVYVEAPLDTDQDGQLDLIKVNIIRPQSQKPLPTLMTPSPYHQGINE
                     VANDKKLYRMEKELVVKKRRQITVEDRDFIPLETQPCKLPIGQNLESFSYINSYSLND
                     YFLARGFANIYVSGVGTAGSTGFMTSGDYAQIESFKAVIDWLNGRATAYTSHSKTHQV
                     RADWANGLVCTTGKSYLGTMSTGLATTGVDGLAMIIAESAISSWYNYYRENGLVCSPG
                     GYPGEDLDVLTELTYSRNLLAGDYLRHNDRYQELLNQQSQALDRQSGDYNQFWHDRNY
                     LKNAHQIKCDVVYTHGLQDWNVKPRQVYEIFNALPSTINKHLFLHQGEHVYMHNWQSI
                     DFRESMNALLCQKLLGLANDFSLPEMIWQDNTCLQNWQERKVFGTSTIKELDLGQELL
                     LIDNHYGEDEFKAYGKDFRAFKAALFEGKANQALVDILLEEDLPINGEIVLQLKVKSS
                     ENKGLLSAQILDYGKKKRLGDLPIALTQSSIDNGQNFSRESLKELLFREDSYRVISKG
                     FMNLQNRNNLSSIETIPNNKWMTVRLPLQPTIYHLEKGDTLRVILYTTDFEHTVRDNS
                     NYALTIDLSQSQLIVPIASN"
     gene            complement(26308..26967)
                     /locus_tag="ACF4ZO_000565"
     CDS             complement(26308..26967)
                     /locus_tag="ACF4ZO_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HFD5486137.1"
                     /translation="MNHHILQRYIDNHNFPIIEKSYHKYLTFESLEEDFTYILKDGIV
                     KQSALSKYGMEFNLRYVTGLEITSVLNTGYSKDMGEPYNVRIESEKASFYKVRRSAFL
                     KDINEDIELQGYVKDFYHNRLQKSMKKMQCMLTNGRIGAISTQIYDLMTLFGEELPNG
                     QILINFVITNEELGKFCGISTASSVSRILKQLKEKNVIRIDKQHIIITNLDKLKDNIV
                     F"
     gene            27133..28329
                     /locus_tag="ACF4ZO_000566"
     CDS             27133..28329
                     /locus_tag="ACF4ZO_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFD5486138.1"
                     /translation="MEEKLFNKHFVAITVINFIVYMVYYLFTVIIAFVATRELGAQTS
                     QAGLATGIYILGTLLARLIFGKQLEVFGRRLVLRGGAIFYLLTTLAYFYMPTISMMYL
                     VRFLNGFGYGVVSTATNTIVTAYIPACKRGEGINFYGLSTSLAAAIGPFVGTFMLDNL
                     HIDFRMIIVLCSVLIGCVVVGAFAFPVKNMSLNAEQLAKTKSWTVDSFIEKKALFITA
                     IAFLMGIAYASVLGFQKLYTSEIHLTAVGAYFFVVYALIITITRPAMGRLMDAKGDKW
                     VLYPSYLFLAMGLFLLGSVSSGGSYLLSGALIGFGYGTFMSCGQAASIQGVDEHRFNT
                     AMSTYMIGLDLGLGAGPYLLGLIKDLALGSGVASFRHLFWLAAVIPLICTLLYLLKTK
                     TRQVVS"
     gene            28801..29649
                     /gene="gla"
                     /locus_tag="ACF4ZO_000567"
     CDS             28801..29649
                     /gene="gla"
                     /locus_tag="ACF4ZO_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aquaglyceroporin Gla"
                     /protein_id="HFD5486139.1"
                     /translation="MEMTWTVKYITEFIATAFLIILGNGAVANVDLKGTKGHNSGWLV
                     IAFGYGLGVMMPALMFGNVSGNHINPAFTVGLAVSGLFPWAHVLQYVVAQLLGAIFGQ
                     LVVVMVYKPYFMKTENPNHVLGSFSTISSLDNGQKDSHKASYINGFLNEFVGSFVLFF
                     GALALTKNYFGVELVGKLIEAGYDQTTAATQISPYVTGSLAVAHIGIGFLVMVLVTSL
                     GGPTGPALNPARDFGPRLLHHFLPKSVLGQAKGDSKWWYAWVPVVAPILAAIVAVAAF
                     KYLYIR"
     gene            complement(29985..30881)
                     /locus_tag="ACF4ZO_000568"
     CDS             complement(29985..30881)
                     /locus_tag="ACF4ZO_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TSUP family transporter"
                     /protein_id="HFD5486140.1"
                     /translation="MNEMLILRLIQALLVSAMLFIFFMLVKHLKKNKINPFKRFWTGF
                     WIGLLTDALDTLGIGSFATTTTCFKLTKLVTDDRQLPGTMTVAHVLPVLIQSLCFIFV
                     VKVEVLTLLAMAAAAFIGAYFGTHITKNWHAPTVQRILGSLLIIAAIIMIIRIIYHPG
                     EHLSDTIHGLHGIWLFVGIGFNFIVGVLMTMGLGNYAPELIFFSLMGLSPTVAMPVMM
                     LDAAMIMTASSSQFIKANRVSWDGFAGIVSGGIIGVLLAVFFLTNLDINSLKLLVIAI
                     VFFTGGMLIRSSFTSHKQQTNR"
     gene            31179..31931
                     /locus_tag="ACF4ZO_000569"
     CDS             31179..31931
                     /locus_tag="ACF4ZO_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA N-terminal domain-containing protein"
                     /protein_id="HFD5486141.1"
                     /translation="MTLMENITFKTPVLRVNDRDLNIAFYQNNLGLRLVSEENAVAIF
                     SSWGEGQECFVIEESPSVRTRAVEGPKKVNTIVIKTNQPKEIEQLLAHGAHYDTLFKG
                     QNGYAFETISPEGDRFLLHAEQDIKHLQGTDLPSLEKDATFKGLTQFKFDIIVLNVIS
                     EERSKAFYRDLFSDQLPITMDFIQEEGPDLAIDPHIAWDLEILEFQVSKDYDMKVLKA
                     TLEEDGHKVYIDKKHKVLVLSDPSQIEVWFTK"
     gene            31916..32866
                     /locus_tag="ACF4ZO_000570"
     CDS             31916..32866
                     /locus_tag="ACF4ZO_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="HFD5486142.1"
                     /translation="MVYEMTLAVIKCIENHLHKKVYKGASLALFQSGRWQEYHIGTID
                     GRRPVDANLVYDLASVSKVVGVATICNILLNNGTLALDDPLKVYYPSIADTTVTIRQL
                     LTHTSGLDPYIPNRDVLNAQQLRKALNHLTQKENKNFYYTDVNFLLLGFMLEELFSES
                     LDQIFDKTIFTPFGMYHTSFGPRPEAVPTLKGVSDGEVHDPKAKILKKHSGSAGLFST
                     LADLESFSNHYLNDPFSDCLWRNYSQQTIERSLGWNLDGDWISHTGYTGPFLMLNKKE
                     QTAAIFLTNRTYDEDDKSKWLKERQLLYNALKHDLTTPVS"
     gene            complement(33046..35373)
                     /gene="pflB"
                     /locus_tag="ACF4ZO_000571"
     CDS             complement(33046..35373)
                     /gene="pflB"
                     /locus_tag="ACF4ZO_000571"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008861 - formate C-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HFD5486143.1"
                     /translation="MATVKTNTDVFEKAWEGFKGTDWKEKASVSRFVQANYTPYDGDE
                     SFLAGATERSLHIKKVIEETKAHYEATRFPYDTRPTSIADIPAGFIDKENELIYGIQN
                     DELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIRRA
                     RHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAITEIDEESIRLREEV
                     NLQYQALGEVVKLGDLYGVDVRRPAQNVKEAIQWVNIAFMAVCRVINGAATSLGRVPI
                     VLDIFAERDLARGTFTESEIQEFVDDFVLKLRTVKFGRTKAYDALYSGDPTFITTSMA
                     GMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDQLPETFRRYCMKMSHKHSSI
                     QYEGVTTMAKEGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNGGY
                     DDVHRDYKVFNVVEPITSEVLEYDEVMANFEKSLDWLTDTYVDALNIIHYMTDKYNYE
                     AVQMAFLPTHQRANMGFGICGFANTVDTLSAIKYATVKTIRDENGYIYDYEVTGDFPR
                     YGEDDDRVDDIAKWLMEAYHTRLASHKLYKNAEASVSLLTITSNVAYSKQTGNSPVHR
                     GVFLNEDGTVNTSQVEFFSPGANPSNKAKGGWLQNLNSLAKLEFSHANDGISLTTQVS
                     PRALGKTFDEQVDNLVTVLDGYFENGGQHVNLNVMDLNDVYDKIMNGEDVIVRISGYC
                     VNTKYLTPEQKTELTQRVFHEVLSMDDAAEAISSK"
     gene            35582..36676
                     /gene="dinB"
                     /locus_tag="ACF4ZO_000572"
     CDS             35582..36676
                     /gene="dinB"
                     /locus_tag="ACF4ZO_000572"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HFD5486144.1"
                     /translation="MLIFPLINDTSRKIIHIDMDAFFAAVEERDNPALKGKPVVIGKD
                     PRETGGRGVVSTCNYEARKYGIHSAMSSKEAYERCPKAIFISGNYEKYRTVGDQIRRI
                     FKRYTDVVEPMSIDEAYLDVTNNKLGIKSAVKIAKLIQHDIWKEVGLTCSAGVSYNKF
                     LAKLASDFEKPHGLTLVLKEDALCFLAKLPIEKFHGVGKKSVEKLHDMGIYTGQDLLA
                     VPEMTLIDHFGRFGFDLYRKARGISNSPVKSDRIRKSIGSERTYAKLLYQETDIKAEI
                     SKNAKRVAALLQDHKKLGKTIVLKVRYADFTTLTKRVTLPELTRNAAQIEQVAGDIFD
                     SLSENPAGIRLLGVTMTNLEDKVADISLDL"
     gene            complement(36769..37251)
                     /locus_tag="ACF4ZO_000573"
     CDS             complement(36769..37251)
                     /locus_tag="ACF4ZO_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486145.1"
                     /translation="MISYEKVRQALKTSTIAIIILNGLGVVLSLMGFAGIFYLQSQLK
                     NEAFRAQLTTEQLAQLQSSMTPFMIFLSVLNVLAIIAIIVFCAQNLSKLKQGLTVSYI
                     PYILGLILSVIGLVNQFTTTMSMVGTILILIQAALYGFAFYKAKTLNEKGDDTDQAML
                     "
     gene            complement(37342..39795)
                     /locus_tag="ACF4ZO_000574"
     CDS             complement(37342..39795)
                     /locus_tag="ACF4ZO_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0043139 - 5'-3' DNA helicase activity
                     [Evidence IEA];
                     GO_process: GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HFD5486146.1"
                     /translation="MEYVFTGTVDRIIFENQANFFKILLLAIEDTDSDIDDFEIIITG
                     TMADIIEGDDYTFWGELTQHPKYGQQLKLSRYQKIKPSSSGLVNYFSSDHFKGIGKKT
                     AEKIIALYGHNTIDHILEDPSKLETISGLSKANRQAFVAKLKLNYGTEQLIAGLVELG
                     LSNRFAFQAFEKYKEEALDLVKENPYQLVEDLQGFGFKMADALAENLGIESDSPKRFR
                     AALLHCLLEESINRGDTYVQARQLLDFAITLLEDARQLECDPAAVAEQLSELIIEGKI
                     KNSDTKLFDASLYFAEEGIANNISRLLDTPLSQSFSHDTIQTTIQAVQKDFAITYDQV
                     QQEAITKALTSKVFLLTGGPGTGKTTVIRGILQAYANLHQIDLDKKDLPILLAAPTGR
                     AARRMNELTGLPSATIHRHLGLNGDNDYQAMEDYLDCDLLIVDEFSMVDTWLANQLLG
                     AINSTTQVIIVGDSDQLPSVGPGQVLSDLLKVNSLPQIALQKIFRQSQESTIVNLADQ
                     MRRGILAADFRDKKADRSYFEAQAAFIPDMIQKIVLSAIKSGIPAEEIQILAPMYKGQ
                     AGINHLNQLMQELLNPLQGQTEFLFNDTYFRKGDKVLHLVNDAQLNVFNGDIGYITDL
                     IPAKYTESKQDELILDFDGSEVTYPRNEWLKLTLAYAMSIHKSQGSEFQVVILPITRQ
                     SGRLLQRNVIYTAITRSKSKLILLGEYTAFEYAIKHEGDKRQTYLIERFQEQSDLASS
                     QPNQELKSKEQTSLFSNTATLEDDSQKSSSQSTNSNPTENSQSDNDDFRLTPENYSTI
                     DSMIGLTESDIALFFQKKS"
     gene            complement(39853..40446)
                     /gene="lepB"
                     /locus_tag="ACF4ZO_000575"
     CDS             complement(39853..40446)
                     /gene="lepB"
                     /locus_tag="ACF4ZO_000575"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HFD5486147.1"
                     /translation="MKQFIKEWGPFTLFLILFGLSRLFLWQAVKVDGHSMDPTLAHGE
                     RLIVFNQARIDRFDIVVAQEEENGQKKEIVKRVIGLPGDTISYNDDTLYINGKKTVEP
                     YLAEYLKQFKNDKLQKTYAYNTLFQQLAETSDAFTTNSEGQTRFEMSVPKGEYLLLGD
                     DRIVSRDSREVGSFKKENLIGEVKARFWPLNKMTVFN"
     gene            complement(40457..41359)
                     /gene="rnhC"
                     /locus_tag="ACF4ZO_000576"
     CDS             complement(40457..41359)
                     /gene="rnhC"
                     /locus_tag="ACF4ZO_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA];
                     GO_process: GO:0006401 - RNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HFD5486148.1"
                     /translation="MNTLVLKIDAILSKHLKKQLAPYTISSQNTYVAFAAKKNGVTVL
                     LYKSGKLVLQGNGANALAQELNLPVAKTVFEASNNSQDIPIIGSDEVGNGSYFGGIAV
                     VASFVDPKDHSFLKKLGVDDSKKLSDKTIQQIAPLLEKQIPHQSLLLSPKKYNELVGK
                     SKPYNAISIKVALHNQAIFLLLQKGIQPKQIVIDAFTSQSNYEKHLKKEKNHFPNPLT
                     FQEKAESHYLAVAVSSIIARNLFLDNLDQLGQDLGYQLPSGAGSASDKVASQLLAAYG
                     MSSLEYSAKLHFANTHKAQALLTK"
     gene            41516..41824
                     /locus_tag="ACF4ZO_000577"
     CDS             41516..41824
                     /locus_tag="ACF4ZO_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486149.1"
                     /translation="MKSINRYKFTFGEKTLTLTTDKDNLFMEEVERVAKEKYQALKNH
                     LPEADDETIAILMAINTLSTQLSREIAIEKMEAEILDLRQKTLVGLQEKANQIDVNEV
                     "
     gene            41827..42372
                     /locus_tag="ACF4ZO_000578"
     CDS             41827..42372
                     /locus_tag="ACF4ZO_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009403 - toxin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HFD5486150.1"
                     /translation="MLSLLIVLVLTWNFYIGYSRGIILQSFYVLGALLSLLVANRFYI
                     GLAHKLTLWIPYSNPVEGTSVFFFKSVDIFVLDKVYYAGLAFFIIFLLGYALSRFLGI
                     FVHFLLLDYFDNQWTKCLSGGLALLVSLLFLNMLLSIFATVPMPFLQHYLHSSFLARL
                     VIEHLPPLTIIIQKLWMQAII"
     gene            42521..44860
                     /locus_tag="ACF4ZO_000579"
     CDS             42521..44860
                     /locus_tag="ACF4ZO_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HFD5486151.1"
                     /translation="MNNKILEQLEFNKVKELLLPYLKTEQSQEELLELEPMTEAPKIE
                     KSFNEISDMEQIFVEHHSFGIVSLSSISESLKRLELSADLNIQELLAIKKVLQSSSDM
                     IHFYSDLDNVSFQSLDRLFENLEQFPNLQGSFQAINDGGFLEHFASPELERIRRQLTN
                     SERRVRQILQDMLKEKAELLSENLIASRSGRSVLPVKNTYRNRISGVVHDISSSGSTV
                     YIEPRAVVTLNEEITQLRADERHEEGRILHAFSDLLRPHVATIRNNAWILGHLDFVRA
                     KYLFMSDNKATIPKISNDSTLALINVRHPLLSNPVANDLHFDHDLTAIVITGPNTGGK
                     TIMLKTLGLAQLMGQSGLPVLADKGSKIAVFNNIFADIGDEQSIEQSLSTFSSHMTHI
                     VSILNEADHNSLVLFDELGAGTDPQEGASLAMAILEHLRLSHIKTMATTHYPELKAYG
                     IETNFVENASMEFDAETLSPTYRFMQGVPGRSNAFEIASRLGLAPFIVKQAKQMTDSD
                     SDVNRIIEQLEAQTLETRRRLDHIKEVEQENLKFNRAVKKLYNEFSHERDKELEKIYQ
                     EAQEIVDMALNESDTILKKLNDKSQLKPHEIIDAKAQIKKLAPQVDLSKNKVLNKAKK
                     IKAARAPRIGDDIIVTSYGQRGTLTSQLKDGRWEAQVGIIKMTLTHDEFTLVRVQEEQ
                     KVKNKQINVVKKADSSGPRARLDLRGKRYEEAMQELDHFIDQALLNNMGQVDIIHGIG
                     TGVIREGVTKYLRRHKHVKHFAYAPQNAGGSGATIVTLG"
     gene            44864..45364
                     /locus_tag="ACF4ZO_000580"
     CDS             44864..45364
                     /locus_tag="ACF4ZO_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017767232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HFD5486152.1"
                     /translation="MESYEHFYAKLSQPFRKSPQLIILLNVLLKIITAMMYILYPSFL
                     IFTLWQGMTFQLWLRLLIIPSVGFIALSYIRKRLDFPRPYEKWNIKPLIDKDTKGRSM
                     PSRHVFSATMISMCLLRYYVYFGIVCLILSVLLAICRVIAGIHYPKDVIVGYLIGLML
                     GLCLLI"
     gene            45427..45759
                     /gene="trxA"
                     /locus_tag="ACF4ZO_000581"
     CDS             45427..45759
                     /gene="trxA"
                     /locus_tag="ACF4ZO_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HFD5486153.1"
                     /translation="MKWRKKMALEVTDATFVEETKEGLVLIDFWATWCGPCRMQAPIL
                     EQLSQEIDEDELKILKMDVDENPETARQFGIMSIPTLMFKKDGEVVKQVAGVHTKDQL
                     KAIIAELS"
     gene            complement(45811..46335)
                     /locus_tag="ACF4ZO_000582"
                     /pseudo
     CDS             complement(45811..46335)
                     /locus_tag="ACF4ZO_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402392.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(46500..47654)
                     /gene="mutY"
                     /locus_tag="ACF4ZO_000583"
     CDS             complement(46500..47654)
                     /gene="mutY"
                     /locus_tag="ACF4ZO_000583"
                     /EC_number="3.2.2.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019104 - DNA N-glycosylase activity
                     [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HFD5486154.1"
                     /translation="MIELKDYGINMWDNETIASFRRTLLGWYDQEKRDLPWRRTTNPY
                     YIWVSEIMLQQTQVNTVIPYYKRFLEWFPQIKDLADAPEEQLLKAWEGLGYYSRVRNM
                     QKAAQQVMVDFGGIFPHTYDDIASLKGIGPYTAGAIASISFNLPEPAVDGNVMRVMAR
                     LFEVNYDIGDPKNRKIFQAIMEILIDPDRPGDFNQALMDLGTDIESAKTPRPDESPIR
                     FFNAAYLNGTYGKYPIKNPKKKPKPMRIQAFVIRNQNGQYLLEKNTKGRLLGGFWSFP
                     IIETSPLSQQLDLFDDNQSNPIIWQTQNETFEREYQLKPQWTDNHFPNIKHTFSHQKW
                     TIELIEGVVKATDLPNAPHLKWVAIEDFSLYPFATPQKKMLETYLKQKNA"
     gene            47822..48115
                     /locus_tag="ACF4ZO_000584"
     CDS             47822..48115
                     /locus_tag="ACF4ZO_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486155.1"
                     /translation="MFQKLKNLIDRYSWFVFIMMILVLFLNYIYPFDPSLSGLQLEWL
                     IMTQVFPGLGIVCAMVAIIFKKFNLFVLALILYFALWLKLFLAFSFFTYFLGV"
     gene            48288..48578
                     /gene="rpsF"
                     /locus_tag="ACF4ZO_000585"
     CDS             48288..48578
                     /gene="rpsF"
                     /locus_tag="ACF4ZO_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HFD5486156.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKDWE
                     KRRLAYEINDFREGLYHIVNLEATDAAALNEFDRLSKINGDILRHMIVKLDA"
     gene            48600..49091
                     /locus_tag="ACF4ZO_000586"
     CDS             48600..49091
                     /locus_tag="ACF4ZO_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HFD5486157.1"
                     /translation="MINNVVLVGRMTKDAELRYTPSQVAVATFTLAVNRTFKSQNGER
                     EADFINCVIWRQPAENLANWAKKGALIGVTGRIQTRNYENQQGQRVYVTEVVADNFQM
                     LESRATREGGSTGSFNGGFNNNTSSSNSYSAPAQQTPNFGRDDSPFGNSNPMDISDDD
                     LPF"
     gene            49256..49495
                     /gene="rpsR"
                     /locus_tag="ACF4ZO_000587"
     CDS             49256..49495
                     /gene="rpsR"
                     /locus_tag="ACF4ZO_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HFD5486158.1"
                     /translation="MAQQRRGGFKRRKKVDFIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPYVNED"
     gene            complement(49628..50284)
                     /locus_tag="ACF4ZO_000588"
     CDS             complement(49628..50284)
                     /locus_tag="ACF4ZO_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HFD5486159.1"
                     /translation="MELQELTKKNQEFIHTATNKLIQDGKSDEDIKLILEEAIPAILE
                     NQKKGVTARNLLGTPTAWAASFSQDPSQRAAETDKNTNPWLMWLDTSLLFIGIVALLN
                     GIMTFFNTNATVTGLISLLALGFGGGASMYATYYFIYRHLGKDKSLRPSWFKIIAALS
                     LAMLIWIALYSATAFLPTSLNPQLPPLALLIIGGVSLALRYYLQRKYNIQNTMSPVNK
                     "
     gene            complement(50416..51360)
                     /locus_tag="ACF4ZO_000589"
     CDS             complement(50416..51360)
                     /locus_tag="ACF4ZO_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HFD5486160.1"
                     /translation="MKQMFLSSAIEFKEIETFEPGAWIKLVNPSQEESMKIADQFNID
                     ISDLRAPLDVEETSRIAVEDDYTLIIVDVPIYEERNNKSYYITMPLGIIVTENAVITT
                     CLHDMTLFDHFHNRRVKNFYTFMKTRFVFQILYRNAELFLTALRTIDRQSERLEAQLE
                     AATRNEELIDMMELEKSIVYLKASLKFNERIVKKLSSSTSSLKKYIEDEDLLEDTLIE
                     TQQAIEMAGIYENVLNAMTETTASIINNNQNTIMKTLALMTMALDIPTVIFSAYGMNF
                     QNNWLPLNGLEHAFWYITLIAMLLSSFVVIYFIRKKWF"
     gene            complement(51604..52701)
                     /locus_tag="ACF4ZO_000590"
     CDS             complement(51604..52701)
                     /locus_tag="ACF4ZO_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015967409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFD5486161.1"
                     /translation="MIKKYTKKDGTTAYCLRAYLGVDPVTGKQVRTTRQGFKTEREAK
                     RAEVKLIDDFQRQGAWKSNDRTTFDDVAKLWFEQYKNTVKPSTFLVNQNYYKTILKPH
                     LGQLQMTKITVMICQKFVNCLSRYSGYTLYLSLANRIFKFAVNLGIIDNNPMSKTLRS
                     KCTYKNVNTLTKKYYTKEELNTFLRIVEAEESLEMRLIYRLLSYGGFRIGELMALKDT
                     DFEFHNNTISITKTIAYTKEGWAVQSPKTKKSTRAISMDAETMSLAKLYIKQSIKPLH
                     GSFKLFNFSCDTVRNRLDKLILKHGLKRITPHGFRHTHASLLFEAGIPAKIAQERLGH
                     AKIAITMDLYTHLSKKSKDDVADKLAELVAV"
     gene            complement(52873..53295)
                     /locus_tag="ACF4ZO_000591"
     CDS             complement(52873..53295)
                     /locus_tag="ACF4ZO_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ltp family lipoprotein"
                     /protein_id="HFD5486162.1"
                     /translation="MKKCSIIAIVVVGVMATATTPELSNKLFSQSVTVVAVSKEYQNA
                     LETAKMVKDANMSKKAFYDMMINESKFEKKAVDYAAKKLKINWKKNALAQAKSMQKFG
                     ASKETIKEQLSANSDGGGFTKKEVNYAIKHLEDNNKDK"
     gene            complement(53367..54107)
                     /locus_tag="ACF4ZO_000592"
     CDS             complement(53367..54107)
                     /locus_tag="ACF4ZO_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFD5486163.1"
                     /translation="MSGSLGNKKIMASNIRRHLEKKNMNPKEFSKAMNFKYSTVLDWV
                     NAKTYPRIDKIELMANYFNVEKSDLVEMYSPEIISATSNIVIQLDKELKEPRHSDWIS
                     YGENLLSEQNTVEDSKNTVVELFSYNYYDHAASAGTGQYLNDVQVEKIELPVDYDADF
                     VIPVYGDSMEPKYHSGDYVFVKLSVDLTDGDIGVFEYYGDAYIKQLLINAEGAFLHSL
                     NSKYDDIPIDADSDFRIIGEVVGSYSGK"
     gene            54467..54616
                     /locus_tag="ACF4ZO_000593"
     CDS             54467..54616
                     /locus_tag="ACF4ZO_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486164.1"
                     /translation="MRERNEKFIGVLKDMHMQILRDFTNEEDPLTRCELAKGFLEIGD
                     YLSKQ"
     gene            complement(54602..54817)
                     /locus_tag="ACF4ZO_000594"
     CDS             complement(54602..54817)
                     /locus_tag="ACF4ZO_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486165.1"
                     /translation="MKISNSKDLALAIVASSSPTLSIEDKIKLYEDSVEAIKQHNLPF
                     VEAEKQEQINNGKVIAEALERGESLFG"
     gene            54876..55034
                     /locus_tag="ACF4ZO_000595"
     CDS             54876..55034
                     /locus_tag="ACF4ZO_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486166.1"
                     /translation="MSWKKLMLGDLEHTFTSRDGKEKTSVEFEGGVLPALLVLGGITW
                     LIAWFITK"
     gene            complement(55133..55774)
                     /locus_tag="ACF4ZO_000596"
     CDS             complement(55133..55774)
                     /locus_tag="ACF4ZO_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001008980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486167.1"
                     /translation="MNFFNFLLCVFKFTSEYLIKNWIALIALFLSYSNYRRNNLQVEL
                     IAAPVSDWILSVILDNGESIYNPNGTLRANIKIINPSNVDVSYFDLIVFDKNRKYQHY
                     YQKQNNIINDLTGREAIAAVQPDGNTILIEVPEADCGVLKAHSMTRMDLIIQTSEITD
                     RLFVAFKVAKKKKLFKANKAGYVNSPYQSFSASFPVELSKKPHYEDILKDLHE"
     gene            55867..56082
                     /locus_tag="ACF4ZO_000597"
     CDS             55867..56082
                     /locus_tag="ACF4ZO_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD5486168.1"
                     /translation="MTKMTLKMLRVSKNWNQETAAKKLKISVSKLSNWENAKTFPDAI
                     EINKIEKLYDVNYSDIIFLPTKHGLTV"
     gene            56230..56436
                     /locus_tag="ACF4ZO_000598"
     CDS             56230..56436
                     /locus_tag="ACF4ZO_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486169.1"
                     /translation="MEIKDMKVSVDVRIKLSNSEAFREMVREFNTKAHELSLIAHELE
                     MFVFEGEIENRVLSDDCNEQSDLA"
     gene            56455..56796
                     /locus_tag="ACF4ZO_000599"
     CDS             56455..56796
                     /locus_tag="ACF4ZO_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486170.1"
                     /translation="MRPKRYPYQKNKLIIQSKNAKTKIELDSGKITINAEEIKVGDLA
                     NEISKVQLANKEIAETIGQDKKSTETVDSRISQLEKEVEGLKGVVGTAYRLATETYHR
                     ISKQSSTSVTE"
     gene            complement(56754..56975)
                     /locus_tag="ACF4ZO_000600"
     CDS             complement(56754..56975)
                     /locus_tag="ACF4ZO_000600"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486171.1"
                     /translation="MSKLTPKNEIQKVYKDWDTIDTVLKYVFEDPIRTDYVAYIYPKE
                     FKIPKDEIIQELQNNGYSVTEVEDCLEIR"
     gene            57119..57304
                     /locus_tag="ACF4ZO_000601"
     CDS             57119..57304
                     /locus_tag="ACF4ZO_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000263688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFD5486172.1"
                     /translation="MWEKIEQLMIERNLNMNKLAKLTGIHKSHFSDLKSGRIKHLSWP
                     NMVKLSTGLKVSLDEFK"
     gene            57382..57639
                     /locus_tag="ACF4ZO_000602"
     CDS             57382..57639
                     /locus_tag="ACF4ZO_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486173.1"
                     /translation="MQSQLTYDLLKKQIAEELFDEFKELIQEKDLANRWVNQTALVNE
                     YGYSWQTIKRMESYGLKSFKNGKDKMYCLADVNEIKHLMKQ"
     gene            57669..57809
                     /locus_tag="ACF4ZO_000603"
     CDS             57669..57809
                     /locus_tag="ACF4ZO_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486174.1"
                     /translation="MKLLDFIFAKPKKQEEKPKWTIENNGWEANARRYNQKHGLPAKQ
                     IW"
     gene            57937..58116
                     /locus_tag="ACF4ZO_000604"
     CDS             57937..58116
                     /locus_tag="ACF4ZO_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486175.1"
                     /translation="MTTTKKLGRPTSNPKSHSKRLRMTDEEVQKLEYCTKQTGKTQTD
                     VLMLGLDKVYQELKK"
     gene            58289..58561
                     /locus_tag="ACF4ZO_000605"
     CDS             58289..58561
                     /locus_tag="ACF4ZO_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486176.1"
                     /translation="MDNSKLENHQKVTVVCTDFNVYLNGIRLTGARPETAKLAERCGE
                     KLITLSLVVTDFDDHRTPKMADMAKEAEMANKTLDWEKKHFYKSNK"
     gene            complement(58551..58931)
                     /locus_tag="ACF4ZO_000606"
     CDS             complement(58551..58931)
                     /locus_tag="ACF4ZO_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486177.1"
                     /translation="MIDYYSLYKNSLEAIGYHKLDTGVDLLQYLIATEEGKRIYSQYP
                     YREVEEIIFYTLDCLIQQDLVTATEMPRLDRRIYTIDGLTPKGMYFLGYIGQVETEVI
                     EWLNEFGVSQNPESIYNALRYIIY"
     gene            58987..59430
                     /locus_tag="ACF4ZO_000607"
     CDS             58987..59430
                     /locus_tag="ACF4ZO_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001074391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486178.1"
                     /translation="MAKIYTLTEEELNELVAERMKQAKEKRTPQGLFKDVSFDDELIP
                     INEKYPKVLKKLNRERAYKPEKHVFNQTPKVFGVDNDISYSKITTHDVHNHIRLLVLN
                     VFGKSQNKEVLPEEYDQAIELYNQLKEWFVSSYDKRLEGLVLEDD"
     gene            59546..60349
                     /locus_tag="ACF4ZO_000608"
     CDS             59546..60349
                     /locus_tag="ACF4ZO_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017285243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006269 - DNA replication, synthesis of
                     primer [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HFD5486179.1"
                     /translation="MAQKSKTKIYYWLKFDKHFFDNLFIKRLLRNFPGGSEMIVIYIR
                     LMLEAIENDCIIDYEGTFDNYAEELALRLETSEEQINMALAYFVKCGVIQVDDGGNTH
                     YPQAKALLGQETNWNRYKKKQAELEKFQLLSNQVPTEIEKDKKIDINIDIKSEVEEEI
                     KDSSSAANVNNLKIISDYFQQEIGILSPNQFEQLSDYITITKMEVDVVKEAITRAADN
                     SKRSFGYVNSILRNWRQNGILTMVKVEEEQRQFQYRKSKQEEVSEYDTW"
     gene            60336..61118
                     /locus_tag="ACF4ZO_000609"
     CDS             60336..61118
                     /locus_tag="ACF4ZO_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017643459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFD5486180.1"
                     /translation="MILGDEDALTKIAISYQQNTKKQDAVCEKHGCRYITVLKTGLTV
                     CPDCHREELDNQNTLHVQKQYERELENKRLYYLKKLSIMDDELENASFDNFRADTAKH
                     KEVLYWAKTMANDWFSGGKGNIIMTGKAGRGKSHLAYSIIRGLSDKTKKLGLLVNVTD
                     LLSEIKRDFSKEAFWMDKLKDVDYLVLDDLGAEKVSDWSTSIIYSLLNKRTNTIITTN
                     LTPAEIRKIYGERIASRIRKGCDKSHIMEFDGMEDERMKLWN"
     gene            61109..61246
                     /locus_tag="ACF4ZO_000610"
     CDS             61109..61246
                     /locus_tag="ACF4ZO_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486181.1"
                     /translation="MELTLTTFFGLSEEHAAKIMALDEDVRTKKIEELRAWRECSKVT
                     F"
     gene            61259..>61560
                     /locus_tag="ACF4ZO_000611"
     CDS             61259..>61560
                     /locus_tag="ACF4ZO_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486182.1"
                     /translation="MVMPLDELEKRIFCYLPIGSNMMVNSKEICRTFDIKDPKTLRDI
                     IHGMVMKGYLIGSSRRKGGGYYLIDNDDERAEAISSLESQVRKEQKRINILKNGNL"
BASE COUNT        19435 a        10578 c        12417 g        19130 t
ORIGIN      
        1 tggcggaatt ggcagacgcg caggactaag gatcctgtga ccgctttagg tcgtgtgggt
       61 tcaagtccca ctctccgcat aatgtaagag gtgaatcatt gattcgtctc tttttgtttg
      121 gttaaatgaa ggataagaag gcatagattt accggagaaa acttttgata atctgctttt
      181 ggaaaacgct ttaagcttgt gaaagactag aaatttatgg aaaattgtgc tagaatgaac
      241 aatgtaaacg ggggagttat cccgaaaaat aagaggaggc cttacaaatg gcaatcgttt
      301 cagcagaaaa atttgtccaa gcagctcgtg aaaacggata tgctgttggt ggatttaaca
      361 caaacaactt agagtggact caagcaatct tgcgtgcagc agaagctaaa caagctccag
      421 ttcttatcca aacatcaatg ggtgcagcaa aatacatggg tggttataaa gtatgtcaat
      481 ctcttattac taaccttgtt gagtcaatgg gtatcactgt tcctgttgct atccaccttg
      541 atcatggtca ctacggagat gctcttgagt gtatcgaagt aggttacact tcaatcatgt
      601 ttgacggttc acaccttcca gttgaagaaa accttgctaa aactgcagaa gttgttaaaa
      661 ttgcacatgc taaaggcgtt tcagttgaag ctgaagttgg tacaatcggt ggtgaagaag
      721 acggtatcat cggtaaaggt gagctcgctc caatcgaaga tgctaaagca atggttgaaa
      781 ctggaattga cttcttggca gctggtatcg gtaacatcca cggtccatac ccagaaaact
      841 gggaaggtct tgctcttgac cacttagaaa aattaacagc agctgtacca ggtttcccaa
      901 tcgtattgca cggtggttct ggtattcctg acgatcaaat caaagaagca atccgtcttg
      961 gtgttgctaa agttaacgtt aacactgaaa gtcaaatcgc tttctctaac gcaactcgtg
     1021 aatttgctcg taactacgaa gctaacgaag cagaatatga tggtaaaaaa ttatttgacc
     1081 cacgtaaatt cttggctcca ggtatgaaag ctgttcaagg tgctgttgaa gaacgtatcg
     1141 atgttttcgg atcagctaac aaagcataat ttagagtatt aaatacccta aagccctctt
     1201 gagggctttt ttagatacaa ttgacatctt aaaatggata ccagtttctg tgaaacaatc
     1261 tttgattgtg aacaaacaaa gcataattta gagtattaaa atctggaccc tgctatctat
     1321 ggtaagtctt tttgttattg ttaaagaggt taagcggaat gttaatatgt tttagctaaa
     1381 aaatgtagtg aaaaatgagt acgtagacta ttgtaatagt aattccgtaa aattgttgaa
     1441 aaagaaaatg ggaaatacct tgtcaaatta agcaccctat gatagaatag ataagtatgt
     1501 ggtgctagca catccgtaaa catattctac gtaggaggaa acagatcaaa atggctaaag
     1561 tatgttattt tacaggacgt aaaaccgttt ctggaaacaa ccgttcacac gcgatgaacc
     1621 aaacgaaacg tacagttaaa ccaaaccttc aaaaagttac tatccttgtt gatggtaaac
     1681 ctaaaaaagt ttgggcttct gctcgtgcgc ttaaatctgg taaagtagaa cgcatctaat
     1741 agaaataagc cttagggctt tttttattag cttatttcta tccataagct agtcagggta
     1801 ataaacgcta ttgttaacta ttctatctct tttacattac ttctaaaata tgataaaata
     1861 ggatgataaa aactttttga ggtagtaact atgactgtaa aaattaatac aaaagatggt
     1921 ctaatcgagc tatccgacga tgtgattgca actgtcgtgg gaggatcagc aacggaaatt
     1981 tttggtgttg ttggaatggc cagcaaaagt gcaataaaag acaattttca atcactactt
     2041 cgcaaagaaa actacgctaa gggtgttgtc gtaaaatcaa cagatctggg tatttctgtt
     2101 gatgtctaca ctgtgatgag ttatggtgtg aaaatcagtg aagtctctaa aaatatccaa
     2161 gaacgcgtga aatttaacct tgaaagtcag cttggtctca ctgctgatat ggttaatgtt
     2221 tacgtgcaaa atattaaggt tgtaggagaa aattagtgtc aaatattaca acaagcttat
     2281 tccaagaaat ggtccaagcg gcagcgactc gccttggcaa acaagcagaa tatgttaatt
     2341 ccttaaatgt ttttcctgtt ccagatggtg atacaggaac aaacatgagc atgactatgg
     2401 acaatggtgc caaggaagtt gctgataaac ctgcgtcaac tgtgggagaa gttggacaaa
     2461 tgttatcaaa aggtcttttg atgggagcgc gtggaaattc tggagttatt acttcacaac
     2521 tttttcgtgg ttttggtcaa agcattaagg gaaaagatga gctgacaggt aaagatttgg
     2581 cacaagcctt tcaagtgggt gtagaagttg cctacaaagc agtgatgaaa cctgttgaag
     2641 gaacaatttt aactgtttct cggggtgcag cgactgctgc cttaaaaaaa gcagatctta
     2701 cagacgacgc cgtggaagtc atgcaagctg ctttagacgg tgccaaaggt gcccttgcta
     2761 agacacctga tttattacca gtccttaaag aagttggtgt ggttgattca ggcggtcaag
     2821 gtcttgtctt tatctatgaa ggtttcctat ctgctttgaa tggcgactat gtgacttcag
     2881 cagactttaa agcgactcct gctaacatgt ctgaaatgat taatgctgag catcacaaat
     2941 ccgttgttgg tcatgtggct actgaagaca ttacctacgg ttattgtact gaaatcatgg
     3001 ttgcccttaa acaaggccca acctatgtga aagaattcaa ctatgatgag tttcaaggct
     3061 accttagtgg ccttggtgac tcgctgttag tggtcaatga tgatgagatt gttaaagttc
     3121 acgtccatac tgaagacccc ggacttgtga tgcaagaagg tcttaaatat ggttcgctca
     3181 tcaagattaa agtggacaat atgcgtaacc agcatgaagc acaggttcaa aagactgatg
     3241 tcgaaaaaaa caaggctgaa gtaaaagact ttggcttgat tgcagtagta gctggagaag
     3301 gtttatctga aattttcaag gcgcaaggtg ttgattacgt gatttctggt ggacaaacta
     3361 tgaatccatc tacagaagat attgttaaag ctattgaagc agttaatgcc aaacaagtca
     3421 ttatcttgcc aaacaataaa aatatcttta tggctgccca atctgctgca gaagtggtgg
     3481 atattccggc tgctgttgtt gcaacacgta ctgttccgca aggatttacc agcttgttgg
     3541 cctttgatcc ttcaaaatct ttagaggaca atgtagcaga tatgtcaact agtctttctg
     3601 acgtggtcag tggaagcgtt actttggcag tccgtgacac caccattgat ggtttagaaa
     3661 tccatgaaaa tgatttcttg ggaatggttg atggtaaaat catcgtttca aacccagaca
     3721 tggaagtaac tctaaaagct gcctttgcaa agatgattga cgaagatagc gagattgtga
     3781 ctatctttgt tggtgaagaa ggtgatcaag acttagcaga agaacttgct gggtatttag
     3841 gagagactta cgaagatgtg gaagttgaga tccatcaagg agatcagcct gtttacccat
     3901 atctcatgag tgtagaataa tagaatacaa taaaaaaaag aggagttagg caaaggtctg
     3961 actctttttg tctatattga tgtcgtaatg agtggtttta gtgatggtaa gcccctaaaa
     4021 aatgagggta atccatcaca aagctaatgg ttacgattta atttgacaaa acctagaaaa
     4081 acattataat tgtattataa caataagtca agagctgaaa acggttcagt tctaagacat
     4141 gacaaggagg agattttatg ttaggaccat ttatctttat tgcttttggg gttattgtaa
     4201 tcctagctat tgttgccagt accctttatg ttgttcgtca gcaatctgtt gccatcgtgg
     4261 aacgttttgg taggtaccaa aaaacagcca ctagtggtat tcatgtccgc cttccgtttg
     4321 ggattgacaa aattgctgcg cgtgtgcagc tgcgtctttt acagtcagaa atcatcgtgg
     4381 aaaccaaaac caaggacaat gtgtttgtaa ctttgaatgt tgccactcag tatcgtgtta
     4441 acgaacaaaa tgtaacagat gcttactaca aattaatgaa acctgaatct caaatcaagt
     4501 cttacattga agatgccttg cggtcatccg tgccgaagtt gaccttagac gaattgtttg
     4561 agaaaaaaga tgaaattgcc ttggaagtac aacatcaagt ggcagaagaa atgtcaacct
     4621 atggatatat tattgtcaaa accttgatta ccaaggtgga gcctgatgct gaagtcaaac
     4681 agtcaatgaa tgaaatcaat gcggctcaac gcaaacgtgt agctgctcaa gagttggcaa
     4741 acgcagataa aattaaaatt gtgacagcag cagaagcaga ggctgaaaaa gatcgattgc
     4801 acggggtagg gattgcccaa cagcgtaagg ccattgtgga tggtttggcg gagtctattc
     4861 aagagcttaa agaagcgaat atttccttaa acgaagaaca aatcatgtcc attttgttga
     4921 ccaaccaata cctggatacc ctcaatacct ttgcggcaaa aggaaaccaa accctttttc
     4981 taccaaatac accaagtggg gtagaggata tccgtacaca agttttatct gcccttaaaa
     5041 caaaataacg tgtaaaaact tggctaaaaa gttgctcaat actggattta gcagaaggct
     5101 atcatacctt gtgaagtggc aaacgacgaa atgaatacat tacttttatt ggagaaatga
     5161 aagtaaaaaa agcctttttc atgattaaca acatagtatt gattaaatgt taagttgtat
     5221 tgacttttaa attaaataag tttaaaatca acttaataag caaaaaggag attttcaatg
     5281 aaatccaaaa aagttgttag tgttatatca cttaccttat cccttttttt ggtgacaggt
     5341 tgtgctaaag ttgataacaa caaatcagtt aatcgtaagc ctgctactaa acaaacctat
     5401 aatagctata gtgatgacca attaagatcg cgtgaaaata ccatgtctgt tttatggtac
     5461 cagcgagctg cggaaactca agcgctttat ttacaggggt atcagttagc aacggatcgc
     5521 ttaaaagaac aactcaataa accaacggat aaaccttatt caattgtatt agatattgac
     5581 gaaacagttc ttgataatag cccttatcaa gctaaaaatg ttttggaagg aacaggattt
     5641 acacctgaaa gctgggatta ttgggtacaa aagaaagaag caaaaccggt tgctggtgct
     5701 aaagactttt tgcaatttgc agaccaaaat ggtgttcaaa tttactacat ttcagacaga
     5761 tcaactactc aagtagatgc tacaatggaa aatctccaaa aagaaggtat tccagtacaa
     5821 ggtcgtgatc atcttctatt cttagaaaaa ggcgtaaaat caaaggagag tcgtcgtcaa
     5881 aaggtcaaag aaacaactaa tgtaacgatg ctatttggtg ataatcttct agattttgct
     5941 gatttttcaa aaaaatctca agaagataga acagctttat tatcagattt gcaagaagag
     6001 tttggaagac gctttatcat tttccctaat cctatgtatg gttcatggga aggtgccatt
     6061 tataaaggtg aaaagctgga tgtgcttaag caactagagg aacgccgtaa aagtttaaaa
     6121 agctttaaat aaagtaattg aaaaagaggt gcaaaagaaa atgtaacctc tttttaagta
     6181 ctattatttt ctgaaaatag ggttaatgac tgaaaaaaat gttgattttg tgaaatgatt
     6241 attttattat tttcatattt tatctttatg ctaggaattg tggtataatg gaggagtata
     6301 aaaaatatta aggagtctat tcacatggct aaattgactg ttaaagacgt tgatttgaaa
     6361 ggtaaaaaag tcctcgttcg tgttgacttt aatgtgcctt tgaaagacgg cgttatcact
     6421 aacgacaacc gtatcactgc ggctcttcca acaatcaagt atatcatcga acaaggtggt
     6481 cgtgctatcc tcttctctca tcttggacgt gttaaagaag aagctgacaa agaaggaaaa
     6541 tcacttgcac cggtagctgc tgatttagct gctaaacttg gtcaagatgt tgtattccca
     6601 ggtgttactc gtggttcaaa attagaagaa gcaatcaatg ctttggaaga tggacaagtt
     6661 cttttggttg aaaacactcg ttttgaagat gttgacggta agaaagaatc taagaatgac
     6721 gaggaacttg gtaaatactg ggcttcactt ggagatggaa ttttcgttaa cgatgcattt
     6781 ggtacagcac accgtgctca cgcatcaaac gtaggtattt cagcaaacgt tgaaaaagct
     6841 gtagctggtt tccttcttga aaacgaaatt gcttacatcc aagaagcagt ggaaactcca
     6901 gaacgtccat tcgtagctat tcttggtggc tcaaaagttt ctgataagat tggtgttatc
     6961 gaaaatcttc ttgaaaaagc tgataaagtt cttatcggtg gtggtatgac ttacacattc
     7021 tacaaagctc aaggtatcga aatcggtaac tcacttgtag aagaagacaa attggatgtt
     7081 gctaaagacc tccttgaaaa atcaaatggt aaattgatct tgccagttga ctcgaaagaa
     7141 gcaaacgcat ttgctggtta cactgaagtt cgcgacactg aaggtgaagc agtttcagaa
     7201 ggcttccttg gtcttgacat cggtcctaaa tcaatcgctg agtttgacca agcacttact
     7261 ggtgctaaaa cagttgtttg gaatggtcca atgggtgtct ttgaaaaccc tgacttccaa
     7321 gctggtacaa tcggtgtcat ggacgctatc gttaaacaac caggagttaa atcaatcatc
     7381 ggtggtggtg attcagcagc tgctgctatc aaccttggcc gtgctgacaa attctcatgg
     7441 atcagtaccg gcggaggcgc tagcatggaa cttctcgagg gtaaagtatt accaggtttg
     7501 gcagcattga ctgaaaaata atagccatta taatatatag taaagggcat gctgatgcat
     7561 gtcttttttt agttgatcat gtagagttat tgaactttcc ctaacttcac ttatcattta
     7621 ctagttttta gatatagtgg tatttggctg acactgcaat tttcaaaagt ttatgacgat
     7681 ttcatatcaa ttggtttata aaagatatcc taatcataaa taaaacgttt accaaaaggg
     7741 ttttatggat tgatatgtta aaatagatag tgaagggata ggtatgaaaa cgttaagaaa
     7801 attattatct aattacaagt ttgatattaa aaagtttaaa ttgggaatga gaacattgaa
     7861 aacaggctta tcggtctttt tagttttatt ggtttttcat ttatttggtt ggaaagggct
     7921 ccaaattggt gctctaactg ctgtgtttag tttaagagaa gactttgata aaagcgtgca
     7981 ctttggcttt tctagaatta ttggtaatag tataggtggc ctactctcct tagtattttt
     8041 tgcattcaat gagatatttc atcaagcttt ttgggttact ttattaattg ttcctatttg
     8101 taccatgtta tgtattatgg ttaatgttgc atgtaataat aaatcaggta ttattggagc
     8161 agtggctgct cttttgatta ttacactgtc tattccaaca ggacaaacgt ttatttatgt
     8221 gacttcgcgg gtatttgaaa cattttgtgg cgtctttgta gctattttag ttaatactga
     8281 tgttgaactt attaaaaata aatggtttaa caaaaaacac agtgatgtta gataatataa
     8341 catatatact tgacaggtta tttttttcag cctataataa ggaagatgaa aggagtttgt
     8401 catgaaagaa aaagaactta gacgctcaat ggctgttttt cctattggaa cggtgatgac
     8461 attaacagat ctctctgcga gacaaattcg ctattatgaa gatcaaggtt taattaagcc
     8521 tgaacgaacg caagggaatc ggcgtatgtt ttccttaaat gacatggacc gacttttgga
     8581 aattaaagat tttttgtctg agggattaaa tattgcagct attaaacgcg aatatgtcga
     8641 gcgtcaaggt aagttaatgc aaaaacaaaa agctctaaca gatgcagatg tcagacggat
     8701 cttacatgat gaaatgctga cacaaagcgg tttttctact ccctcacagc atattggtaa
     8761 ttttcgtatt taagatatga attgtataaa atttaaagga gacctattta atggcaataa
     8821 cagtagctga cattcgtcgt gaagtcaaag aaaaaaatgt aacgtttctt cgcttgatgt
     8881 tcactgatat catgggcgtt atgaaaaatg tggagattcc tgcaactaaa gaacagttag
     8941 acaaagtatt gtctaacaag gttatgtttg atggttcatc tatcgaaggt tttgtacgga
     9001 tcaatgagtc agatatgtac ctttaccccg atttagacac ttggattatt tttccctggg
     9061 gagatgaaaa tggagcagtt gcaggtttaa tttgtgatat ttatacagca gaaggaaagc
     9121 cttttgcagg agatcctaga ggaaatttaa aaagagccct gaaacacatg aacgagatcg
     9181 gctacaaatc atttaatctt ggaccagaac cagaattttt cctttttaag atggatgata
     9241 aaggtaatcc gacacttgaa gttaacgata atggtggtta ttttgattta gcgccaattg
     9301 acttagcaga caacacgcgc cgtgaaattg tgaatatttt aacgaaaatg ggttttgaag
     9361 tggaagctag tcatcatgaa gtggctgttg gtcaacatga gattgatttt aaatatgcag
     9421 atgttttgaa agcttgtgat aatattcaaa tttttaagct agttgtaaaa acgattgccc
     9481 gtgaacatgg actttatgct acttttatgg ctaaaccaaa atttggaata gctggatcag
     9541 ggatgcactg taacatgtct ttgtttgata accaaggtaa taatgctttt tatgatgaaa
     9601 ctgataagcg aggaatgcag ctatcagaag atgcttatta tttcttggga ggactaatga
     9661 agcatgctta taactacact gctatcacta accctacagt gaattcttat aaacgattag
     9721 ttccgggtta tgaggcacct gtttatgtcg cttgggctgg aagtaatcgt tcaccgctta
     9781 tccgtgttcc agcatcacgt ggtatgggaa cgcgtttgga gttacgctcg gttgatccga
     9841 cagctaatcc ttatttagcc ttggctgttc tcttggaagc tggattagat ggtatcatta
     9901 acaaaattga agctccagaa cccgttgaag ctaatattta taccatgaca atggaagaac
     9961 gaaatgaagc aggcattatt gatttgccat caacgcttca taatgcctta aaagctcttc
    10021 aaaaagatga tgtggtacaa aaggcactag gataccatat ctacactaat ttcttagaag
    10081 caaaacgaat tgaatggtct tcctatgcaa cttttgtttc tcaatgggaa attgaccatt
    10141 atattcataa ctattagagt tatcaggacc tgctcaagtt gagtgggtct tttggatgag
    10201 ctattgtatt tgagctagca agctattatt agctgatcgg acaccaattg attttccatt
    10261 atagaaaact aaaaaccagt ccatgttcta tgaggactgg tttttagttt gataattatc
    10321 tgaactagaa ctgatatatt aaagatatag acagatagta ttaagaaatg agtcttattt
    10381 gattttagtg cttatcaggt gttaagacca tcggaattat aattggttca cgctcagtct
    10441 tttcatacaa gaatggacga agagcattga cgatagcacc gttaactgat tggatgctag
    10501 catccttatt ttttaaagca atacggatag cgttaaagag cacacgttgg ctttcgcgga
    10561 tcaagtcacc tgactcacgc atataaatga aaccacggct cagaatatct ggtccagcta
    10621 aaatcatttg tgtgttaaaa tcaacagttg caacagctaa gacaacacca tcttctgaca
    10681 aatcacggcg gtctcgtaaa acggctgctc caatatcccc gatgccatta ccatccacgt
    10741 agatgtcttg ggcattaaag tgaccagcaa tacgcgcact gtcactggtt aaagctagaa
    10801 cgtctccatt ttccataata aagatatttt cttttggaat accaatatcc atcgccagtc
    10861 ctgcatgaac tttttgcatg cgatactcac catgtactgg catgaaatat tttggtttaa
    10921 tcaaactaag catgagcttt tgttcttgct gtcctccatg accagaagta tgaatattat
    10981 tgacttttcc atgaataaca tcaacaccag cttcttggat ggtattgatt aatttattga
    11041 cacttgtggt attaccaggg attggacttg atgagaaaat cacagtatca ccaggctgta
    11101 aagttacttg acgatgagtg ccattagcga tacgagcaag tgctgccata gactcacctt
    11161 gactacctgt acacataatt aaaacttcac tagcatgaag atttttaagt tcgcttggct
    11221 caatgaaggt accttttgga actttaatat agccaagttc aataccgttg acaattgctt
    11281 tttccataga acgaccaaaa acggcaattt tacgtcccgt tttaacagca gcttctgcag
    11341 cctgttgcaa acggtagatg tttgaagcga aggaagcaaa aataatacgc ccatgaatac
    11401 cttcgataat ttttaaaatg gattggccaa caactttttc agagttagta aaggttggga
    11461 tttcagcatt agttgagtct gataataagc aaaggacacc ttcttcacca agcgctgcca
    11521 tacgttgtaa atctgcagga tctcctactg gcgtgaagtc aaatttaaaa tcaccagtac
    11581 agataatctt accttgaggg gtgtgaataa caataccgac cggttctgga atggaatgag
    11641 tagtcttgaa gaaagtgacg ctcatatttt taaaagttaa ctcggtgttg tgattgattt
    11701 cgtaaacagt tgcttcacgc caaagaccat gttcttccaa tttaccacgg ataagagcaa
    11761 gtgctaaagg tcctgcgtag atagggatat tagcctgttt gagaagaaat ggaataccac
    11821 caatgtggtc ttcgtgacca tgtgtaataa caagagcttt gacccggtct aagttatcga
    11881 caatgtaaga atagtctgga ataacgtaat caattcccaa aagatcatct tctgggaatt
    11941 tgataccggc atcaacgata atgatctcgt cttgatactc aataccataa gtattcttcc
    12001 caatctctcc cagaccacca atggcaaaca ccccaacttc attaggtttt aaactgatat
    12061 ttgtcatctt agaactccgt taattcaaaa acaccggtct ctttttcgta atcgaggtgt
    12121 ttgtcagaaa gtagctcgat aaattccacg ttataatagg tgttatcttc aacgagacga
    12181 cgagccttga tacggccatc gagttcatca gtagcatcaa tattaagata gagtgcttta
    12241 gtactttcac gacgtgggct ttgatccttt gtttcttgat agaaaacttt ataaatcatt
    12301 tgtttttttc ctttcgttat gaatcaatta tccaaacaat aataaatagg tcaaaaggta
    12361 ggtgttccat tttaacggtt ttatatgttg tcattattgt gtagtagatt aattcctgat
    12421 tctgtgcaat tattacaatt ataccataaa cttagctttt agtaaaaaat ttaggtacat
    12481 ttatggtata gtctaaatca aattaagagt cagccttttt gtttatgatt cttaatttgt
    12541 gttataattg atactagaac ttgcagtaga aaggcataaa atgaagacac ttgcatttga
    12601 tacctcaaat aaaaccttgt cccttgctat acttgatgat gagacacttc tagcagatat
    12661 gacccttaac attcagaaaa atcatagtgt tagccttatg cctgctattg attttttgat
    12721 gacttgtact gatcttaaac ctcaagattt agaaagaata gtggttgcaa aaggccctgg
    12781 atcttacaca ggtttacgag tggcagttgc tactgcaaaa acgttagcgt acagtttaaa
    12841 tattgcattg gtcgggattt cgagtctata tgctttggct gcgtctactt gtaaacagta
    12901 tccaaatact ttggtggtgc cattgattga tgctagaagg caaaatgcgt atgtaggtta
    12961 ttatcggcaa ggaaaatcag tgatgccaca agcccatgct ccactagaag ttattataga
    13021 acaattagta gaagaagggc agctgatttt tgttggggag actgctcctt ttgctgagca
    13081 aattcaaaag aaactacctc aggcgatact acttccaacc ctgccttctg cttacgaatg
    13141 tggtcttttg gggcaaagtt tggcaccaga aaatgtagac gcctttgtcc ctcaatatct
    13201 caagagagtg gaagctgaag aaaactggct caaagataat gagataaaag atgatagtca
    13261 ctacgttaag cgaatctaat atgaaaacag ttgaagaaca agcaaaaaaa atttatcagc
    13321 ttttggaaat ggtttatggc acgtctcctt ggactttaga acaagtatta atcgatatac
    13381 ggcgggatca aacagattat ttcctattat atgattacga taaattgcta ggttttttag
    13441 ctattcaaga tttatctggt gaagttgaaa tgactcaaat tgctatacta cctagtcatc
    13501 aaggacttgg gctagcgtct caattgatga cgcatttagg tagcattgaa agtgacatct
    13561 ttttagaggt tagagaatct aatcatagag cacagggttt atatcagaag tttggtttta
    13621 aatttattgg caaaagacca gactactata gaaatcctat agaaacagct ttattgatga
    13681 aacgggaagg aaaacatgac agataggtat attttagcag ttgagagttc ttgtgatgag
    13741 accagtgtag cgattttaaa aaacgaaagt acactcttaa gtaatgtcat tgcaagtcag
    13801 gttgagagcc acaaacgctt tggtggtgtg gtgccagaag tagctagtag acaccatgtc
    13861 gaagtgatta cgacttgctt tgaggatgct ttgcaagaag ctggcatcag tgcttcagat
    13921 ttatcagcag ttgcggtaac ttatggccct ggacttgttg gagccttgtt agttggatta
    13981 gcagctgcga aggcttttgc ttgggcaaat catttacctt tgattccggt taatcatatg
    14041 gcaggtcact taatggcagc gcgtgaacaa gagcctttag tttatccttt aatagcactg
    14101 ttggtttcag gaggacacac agaattggtt tatgtcccag agccagggga ttatcatatt
    14161 attggcgaga cgcgtgacga cgctgttggt gaggcttatg ataaagttgg gcgtgtgatg
    14221 ggcttaacct atccggcagg acgtgaaatt gaccagttgg ctcataaagg tcaagatact
    14281 tatcatttcc ctcgtgctat gataacagaa gaccacttag aattttcttt ttcaggactc
    14341 aagtccgctt ttatcaatct tcatcataat gctaagcaaa aaggcaatga actgattcta
    14401 gaagatttgt gtgcatcttt tcaagcagct gttctagata ttttattggc caaaacaaaa
    14461 aaagctctga gcagataccc tgcaaaaatg cttgtagtgg ctggtggtgt ggcggcaaat
    14521 caaggattac gagatagatt agcacaagaa attacacata tagaagttgt gattcctaaa
    14581 ctaagactct gtggagataa cgcgggtatg attgctttag cagcagctat tgagtatgac
    14641 aaacagcatt ttgctaatat gagcctaaac gcgaagccta gtttagcttt tgaccagttt
    14701 ccagacagtt ttgtaataaa ctagtcacac ttgctagtta gtaagattta taatggataa
    14761 gaatctccct ttgaaaaaac aacccggtat cttggcatac cgggttgtca tgacgataag
    14821 taattggctt ctatggttac taataattca gataattacc tgcaaaataa ttgtctgcct
    14881 aaggtgaagt aagcttacca gctagcttta gtgacgccag gaagctgtcc tttgtgagct
    14941 aagtcacgga aattgatacg gctaacacca aacttacgca tgtaagcatg aggacggccg
    15001 tcaattttgt cgcggttctt caagcggttt ggatttgaat cacgaggcaa tttgcgcagt
    15061 gattcataat cgcccttcgc ttttaagtca cgacgaaggt cagcgtactg ttcaatcagt
    15121 tggagctgct tttggtattt agcaattttt gacttttttg ccattgcttt ctccttctta
    15181 atatttaata acctcagagt cgttatcagc gctctgaatc cacttaaccg atatttaact
    15241 ggttaagtgg atatataatc attatacaat aaataaaagc aaaagcaaat aaaaaaatta
    15301 actagttatc ttttttagcc ataatatcaa aaaactccac atctaagtgt gggagtcagg
    15361 tattaataac tgtttaaagg tgtttaatga gtgtcgcttt ggcaactttg agattgaact
    15421 tttaagtcaa ataaatcagc aggaacgtag tgtttggttg agaccaagat gtctttacca
    15481 ttgtagagag tttcttggat taaaataaaa gcactatttt ctgatagagt atacttagtt
    15541 gctgtgtaat tgccagtctt ggtatagccg atttggttgc aggaatgaga agctttacca
    15601 gagtcataga ttttctcttc taagaaagta agaaggggct cttcttgatt gagatttata
    15661 gcatatttag aaataacctc aatagggata aaagataaac tataagcaat agctttattt
    15721 tggctatgat accagcgatc aacaataatc acaacaggag tttcttgttt tagggatgct
    15781 gtaatggcaa cagtgggcac ttcaatccga tattccaatt caacctttgt gatgtcagat
    15841 gataggcttg catatatggg gtgttgaaga tattcgaaac cttggtgata tttagtttca
    15901 ggagtcttga gtataaaatt tccctttcct ctgatatttt ttatgagatg atcctcttgg
    15961 aggagggcta gggatttacg tagtgtcatc cgactgacat tgagctgtct agcaagttca
    16021 ggttctgatg gcagttgcat gccaggacta tatgtaccat cttgaataag ttgaaaaata
    16081 gtattatata cttgcacatg tttaagtttt ttgagttttt tggttaagtc gttagtagac
    16141 atatcactta cctcatttaa taatctttag tggagtttaa cttgtctaaa aactatttta
    16201 gcactaacag tattccttga ttagaattgt acccatctat agtgttagta tctcacactc
    16261 aggtactttt tgtcaaaaag agatgaaaaa caccttaaaa aagcgtttac aaaatagagt
    16321 gtgtgtgata ctatacaagt gtattaaaaa ttagacaagt aaaatacagg aggtttttaa
    16381 catgcaaaat tattcaggtg aagtcggatt gcaatatcac ctacagattc gtccaggtga
    16441 tgtaggtcgt tatgttatca tgccaggtga tccaaaacgt tgtgcaaaaa ttgcagaaca
    16501 ttttgataat gcagttcttg tagcagacag ccgtgaatat gttacgtata caggtacatt
    16561 aaacggtgaa aaagttagtg ttacttcaac tggtattggt ggtccatcag cgtctattgc
    16621 gatggaagaa ttgaaacttt gtggcgctga tacctttatc cgtgttggaa catgtggtgg
    16681 tattgaactt gatgttaaag gcggagacat cgttattgca actggagcta tccgtatgga
    16741 aggtaccagt aaagaatatg ctccgattga atttcctgct gtagctgact tggaagtgac
    16801 aaatgctcta gttaatgcag ctaaaaagct tggttataca agtcacgcag gagtagttca
    16861 atgtaaagat gcattttacg ggcaacatga gccagaacgt atgccagtta gttatgaatt
    16921 attaaataaa tgggaagcat ggaaacgtct gggaacaaaa gcgtctgaaa tggaatctgc
    16981 agctcttttt gtagcagcaa gtcatctagg agttcgttgt ggatcagatt tccttgttgt
    17041 tggtaatcaa gaacgcaacg ctttgggtat ggataaccca atggctcatg atacagaagc
    17101 agctattcaa gttgctgttg aagcactccg cacacttatt gaaaatgata aatcacaata
    17161 agcgaggttt tggaagtcat catgcaattt atttatagta ttattggtat tttattggta
    17221 ttaggaattg tgtatgcaat ttctttcaat cgtaagagtg tttctctaag tttaattgga
    17281 aaagctctta tcgttcaatt cattattgcg ctaatcttag tacgtatccc actaggccaa
    17341 caaattgtta gtgttgtttc aactggagtt actagcgtaa tcaactgtgg tcaagctggt
    17401 ttaaattttg tgtttgggtc attagcagat agtggcgcaa aaactggttt tattttcgct
    17461 attcaaacgc ttggtaatat tgttttctta tctgccctag ttagtctact ttattatgtg
    17521 ggaatccttg gatttgtagt aaaatggata ggtaagggcg ttggtaaaat tatgaaatcc
    17581 tcagaggttg agagttttgt tgctgtagct aatatgtttc ttggtcaaac agacagtcca
    17641 atcttggtta gcaaatacct aggtcgtatg actgatagtg agataatggt tgtgttggta
    17701 tcaggtatgg gaagtatgtc agtttctatt cttggtggct atattgcatt aggcattcca
    17761 atggaatatc tcttgattgc ttcaacaatg gttcctattg gcagtattct cattgctaaa
    17821 atcttattgc ctcaaacaga acctgttcaa aaaattgatg acattaagat ggataataaa
    17881 ggtaataacg ccaatgtgat tgatgcaatc gctgagggtg caagcacagg tgcacaaatg
    17941 gctttctcaa ttggtgctag tttgattgcc tttgttggtt tagtttcttt gattaatatg
    18001 atgttaagtg gattgggaat ccgcttagaa caaatctttt catatgtttt tgctccattt
    18061 ggttttctta tgggatttga ccacaaaaac attcttctag aaggaaacct tcttggaagt
    18121 aagttgattt taaatgagtt tgtttcgttc caacaattgg gtcacctaat caaatcttta
    18181 gattatcgta cagcattggt agcaactatt tcactctgtg gttttgctaa tttatcaagt
    18241 ttaggtattt gtgtttcagg tattgctgtt ctttgcccgg agaaacgtag caccctagct
    18301 cgacttgttt tccgtgcaat gattggtggt attgctgtaa gtatgcttag tgcctttatc
    18361 gtcggtattg taactctatt ctaaacgttg acaaaagaaa gaaggatagt aacgtggaag
    18421 taaaagatat tttaaaaacg gtagaccata ctttgctagc aacaacagca acgtggccag
    18481 aaatccaaac aattttagat gatgccatgg cttatgaaac agcttcagca tgtattccag
    18541 cttcttacgt caaaaaagca gcagaatacg tttcaggtaa attagctatt tgtactgtta
    18601 ttgggttccc aaatggctat agtacaactg cggcgaaggt ttttgaatgt caagatgcta
    18661 ttcaaaatgg tgctgatgaa attgacatgg tcattaattt gacagacgtt aaaaatgggg
    18721 attttgatac tgttgaagaa gaaattcgtc aaatcaaagc taaatgtcaa gaccatatct
    18781 taaaagttat cgttgagaca tgtcaattaa ctaaagaaga acttatcgaa ctttgtggag
    18841 ttgtcacacg ttcaggtgca gactttatta aaacctctac tggtttttcg acagcaggtg
    18901 ctacatttga agatgttgaa gtgatggcaa aatatgtcgg cgaaggtgtt aaaattaagg
    18961 cagcaggtgg aatctcatca ttggaagatg ctaaaacatt tattgcttta ggagcttcac
    19021 gcttgggtac tagccgtatc atcaagattg ttaagaacga agctacaaaa cccgatagct
    19081 attaacttaa tcataccgat ttagcttgag actaaaacaa aaaactcatg taataggagt
    19141 taaaaagcct actatcttag tgataatagg cttttttagc tatgaagact tccctgcgat
    19201 ccatcctgaa caaagagctg aggtaatatt aaaccctccg gtgtgagcat taatatctaa
    19261 gacctctcca gcgaaataca ggccaggaac tttcttgctt tccaaggttt tagggttgat
    19321 ttcttttaaa tctacgcctc ctttggtcac aaatgattta gccaaagaca tttttcctgt
    19381 aatgggtatc tggaggtgtt tgagtttatc aagcaattcc ttttcttgtt ttggagagag
    19441 ttgtttgacc ttttcggggt aatcttctga taaaaaatca gctactcgtt caggcagtag
    19501 gcctttaaga gcatttttga tgtttttatc acgttgatca ctcagataag cggttaagtc
    19561 atctgttgat aagtgtggca aaaagtccag ctctgcaatt tccccacctt tcacaaaaga
    19621 ggacagacga agagctgcag gtcctgaaag gccaaagtgg gtgaagagta agtcgtgtgt
    19681 gatgacgtgt ttgtcataac taagagtaac gtcgtctagg gaaatacctt gcaagacttt
    19741 gtgaggaaaa tcagttaaca gagggctctc agcagcttct aaatcagtca cggtcagttt
    19801 aaaatgccgt gcaatatcat gtccaaaacc tgttgaaccc gttgaagggt aggacttgcc
    19861 tcctgtggtc acaatcaatt tttggcaggt gaaagtctgg tctgcagatt tgaggtagaa
    19921 gaggtcatct tgttttttaa cggaaaccac ttcagtgctg gttagcacct gacccccaag
    19981 agccttgatt tttttctcca gagcatcaat gattgtcctt gatttatctg ttgtggggaa
    20041 catccgtcca tggtcttctt ctttgagttt gacgccgttt tcctcgaaaa aggcaatgat
    20101 gtcatggttg tcaaactggg aaaaaacact atataaaaag cggccatttc caggaatgcc
    20161 agccataagg acatcaaggt taccactatt agtgacatta cagcgtccac caccggttcc
    20221 cgctaatttt ttgcctaagc ggcgattttt ttcaattaag agagttttat agccatagta
    20281 gctgctggag atggcggcca tcatgccagc agggccacct ccaataataa tcgtatcgta
    20341 ttgagtcata gccttatttt agcataaaag cgggggattt aatagtcagg taaatgaact
    20401 aacatggcat accgtttttt acgcatttaa acaatgcttt caagaaataa ttgatgcctt
    20461 tagcacgact gaaatgaggt caaattgaca gaatactcct attatggtac tatttttaat
    20521 aagaatattc agtgatagtg ataaagagga aaatatggga attgaaaaga cagttagtga
    20581 actagctgat attttgggag tgagtcgtca ggccgtcaat aatcgtgtta agtctttacc
    20641 cgaagaagat cttgacaaaa atgaaaaagg cgttactgtg gttaagcgca gtggtcttgt
    20701 taagctggaa gagatctata aaaaaacaat ttttgacgat gagcctatca gtgaagaaac
    20761 gaaacaacgt gagcttttag agattcttgt ggatgagaag aacactgaaa tcacgcgcct
    20821 ttatgagcaa ctcaaagcca aagatgctca acttgcctca aaagatgagc aaatgcgtgt
    20881 taaagacgtg cagatcgctg aaaaagataa acaattggat cagcagcaac aattaactgc
    20941 taaagccatg gctgataaag aaaccctaaa actagaattg gaagaagcta aagcagaagc
    21001 caaccaagct cgcttacaag tcgaagaagt tcaggctgaa gttggcccta aaaaaggctt
    21061 tttaacccgc ttgtttgcga aataatcaca aaaaatgacg aaggccctat cagggtcttt
    21121 tttggaggaa aacatgaaac acttagatac ttatattgcc tttgatttag aatttaacac
    21181 tgtcaatgac gttagtcata tcattcaagt atcagcagtc aaatatgacc accataaaga
    21241 agttgacagc tttgacacct atgtttacac agatgttccc ttacagagct ttatcaatgg
    21301 cctaacagga atcacatctg acaagattgc tgcggcacca aaagtagagg aggttatggc
    21361 tgcgtttaaa aattttgtgg gagagttacc actgattggt tataatgctc aaaaatctga
    21421 cctgcctatt ctagctgaaa atggcttgga tttaagggac caataccaga ttgacctctt
    21481 tgatgaagct tacgatagac gtagcgcaga cttaaatggg attgctaacc ttcgtctgca
    21541 aacagtggca acctttttag gcattaaggg tcgaggtcat aatagcttag aagatgccag
    21601 aatgacagca gcaatctata aatctttttt agaaacagat acaaacaaag catatctcag
    21661 ccagcaagaa gaggtaacca cagatacccc tttcgcagct ttgggagact ttttcgacta
    21721 aaggctctgc tatttttgaa aaataaaaaa atccctaggg ttagcccttg cttataacgc
    21781 taggtcatgt gataagctag ggacatatca agagggagtc gagtgcacac gaatcgtttt
    21841 tgatcactaa atgatagaaa gaaggtgtgg aaatgtctca attctattcg actggagaac
    21901 tggccaactt agctggcgtt tctattcgaa ctgtccaata ctatgaccaa cgtgggattt
    21961 tgattccgac agcattgaca gcaggtggac ggcgactata tacggattct gatttagaac
    22021 aattacgcat gatttgcttt ctgcgcgatt tgggattttc cattgagcag attcgcaaag
    22081 tcttagcaga ggaaaatgca gcccaggtgc tggaattgct tctagttgat catattgcga
    22141 ctgccaagga agacttggcc gcaaaagagc aacaagttga catagctgtc aagatacttg
    22201 acagacttcg aaaacaagac ccccagtcac tagattttct gatggacatt tcgcttagca
    22261 tgaaaaatca aaaagcttgg aaaaaattac aatggaagat gggtatcagt atatttttag
    22321 ccattgtttc atatgtagga cttattttac tatctaatta tctgcaaaaa ttttggttag
    22381 tttatgttgc tatgggacta tttctaccag gtttcagttg gttggtaatt tattttagga
    22441 agcaatttat ttatctctgt ccccattgtc atcagaaatt tgaacctagc tttaatgaat
    22501 ttgcccttgc aggccataca ccacgaacca gaaagttaac ctgctcccat tgccatcaaa
    22561 aatcgtattg cttggaactg gcaaaagagg acactgtctc aagaggataa gcactaactc
    22621 ataaaaaaac tagcctgaga tccttctcaa gctagttttt gtttttttag aatggtaatt
    22681 taccagcaaa agcgcctaat gttttcttag ttgcttcatc aatttgcgta agggcatcat
    22741 taatggcttg tgtggtcatg tcttgaagcg tttctacatc ttcaggatct acaacagctt
    22801 ctttgaagtc aatcccaacc aattttttat cacccgtgaa agtggcagtg acaaggtctt
    22861 gagctgattt tccagtaaat tgcatagcag ccaaatccgc ctgcttttgc tccatttgtt
    22921 tctgaagctt ttgtgcctgc ctcatcatat tctgcatatt catcataaga ctatactctc
    22981 cttaatttaa tactaactat tataacatat aaaaagaggc aataaaaaca atgtcagtta
    23041 gtagactagc ctgtatcagt aagaaagtcg ctatggataa gatggattag cagcaagggt
    23101 ctggctaatg acagaataag tctagaaatg aactattttt gtcatagact agtccgactt
    23161 agtggttatc taattcacga tcttctttag cttgttgttc taaaagaatt tgtgcgaagt
    23221 caacccactt agtgtagtta ttttcggata attgttctga aatcatcgct aactctcgtt
    23281 gtggcaactg ataagagact cccttatttt ctaaggttaa atcttcttcc attagggcgg
    23341 ttaaactaac atcaaagata gcagcaatat cacttaatag accagacttt ggagtatatt
    23401 ttcctttttc ccactcactg attgaagaag agctttttcg tcctaggaga ttagcaagtt
    23461 ctaattgttc catgttcttt tttaatctaa ggtactttaa attacttgca aaaaaagttt
    23521 tcttggcgga catatttttc tccttttctt tatataaaat atgataccat aaaagaggtt
    23581 aaagcaaaag gtatcgtaaa agatggtcta aaaactctct aaaaacttga cttcataaaa
    23641 accgaagttt ataataaact taacatgatt aactaatctc attttagtgt ggagggaaaa
    23701 ttgtgaccaa atcaacttta aaagagttaa gaacaacaaa gaaaatgaca cagcaggaat
    23761 tgtctcactt aacaggcatt tctgtcagaa cgattgctag gtatgaaaaa gatactaaaa
    23821 agctaaggcg agcaaaatat gagaagctaa aaggtattgc acaagcatta gcggtttccg
    23881 ttgatgatat ttttttagga atagattcgg aatttatgaa ctaagacgat cgttttctgt
    23941 ttgctattag taagaccaat taacaaaaaa gtgcttagtt atattgctaa gcacttttct
    24001 ttgttaattt gatgctattg gcacaatcaa ttgagactga ctgagatcga tagttaaagc
    24061 atagttgctg ttgtcacgga cagtatgttc aaaatcggtt gtgtataaga tgactcgaag
    24121 ggtatctcct ttttctagat gatagatggt tggttgcaaa ggaagtctaa cagtcatcca
    24181 tttattatta ggaatagttt caattgacga caaattattg cgattttgta aattcatgaa
    24241 acctttcgaa ataacacggt aagaatcttc tctaaatagt agctctttaa gggattctct
    24301 agagaaattt tgcccattgt caatacttga ttgggtgaga gcaataggaa gatcgcccaa
    24361 gcgttttttc ttaccatagt caaggatttg tgcagataga agtcctttat tttcacttga
    24421 tttcactttt aactgtagaa caatttcacc gttaataggt aagtcctctt ccagtaaaat
    24481 atcaaccagg gcttgattgg ccttgccttc aaagagagct gctttgaacg cacggaaatc
    24541 tttaccgtaa gctttaaatt catcttcacc atagtgatta tcaattaaaa gcagttcctg
    24601 accgaggtca agctctttga tggttgaggt tccaaagact ttacgctcct gccagttttg
    24661 taggcaggtg ttatcctgcc agatcatttc aggaaggcta aaatcattag ctaggcctaa
    24721 gagtttttga cataaaaggg cattcatgct ttcgcgaaaa tcaatggatt gccaattatg
    24781 catgtaaaca tgctcacctt gatgtaaaaa gaggtgcttg ttgattgtgg aaggaagcgc
    24841 attgaaaatc tcatagacct gtcttggttt gacattccag tcttgtaagc catgagtata
    24901 aacgacatca cactttattt gatgagcatt ttttaagtaa ttgcggtcgt gccaaaattg
    24961 attataatca ccagattgtc ggtctaacgc ctgagactgt tggtttagca attcttgata
    25021 acgatcatta tggcgaagat aatcgccagc caataaatta cgcgagtagg tgagctcagt
    25081 taggacatct agatcctctc caggatagcc accaggacta caaactaagc cattttcgcg
    25141 gtagtagtta taccaagaag aaatagctga ttctgcaata atcatggcta atccgtctac
    25201 gcctgtagtg gctaaaccag tagacatagt tcccaagtag gactttccag tcgtacaaac
    25261 tagaccattt gcccaatcag ctctcacttg gtgggttttt gagtggctgg tgtaggctgt
    25321 ggctcttcca tttagccaat caataacggc tttaaagctt tcaatttgag catagtctcc
    25381 actcgtcata aagccagtgg aaccagcagt tcccacacct gaaacataga tattagcaaa
    25441 cccacgtgcg aggaaataat cgttgaggct ataggagtta atgtagctaa agctttctag
    25501 attttgacct ataggaagtt tgcaaggctg tgtctcaaga ggaataaaat ccctgtcttc
    25561 gacagtgatt tgtctccttt ttttaacgac taactctttt tccatacgat aaagtttttt
    25621 gtcgttggct acttcattga taccttgatg gtatggacta ggtgtcatca aagttggtaa
    25681 tggtttttga gattgaggac gaatgatatt aaccttaata agatcaagtt ggccatcttg
    25741 atcggtatca agaggtgctt caacgtaaac aacttctcga atcagctgtg acgtgtcaaa
    25801 ggtagctaat gatttaccgt tgaagaagtg gtaatcattg tccatagtaa gcattccttg
    25861 gctgaccaaa tcatcaatca gggtcatgcc agacttacaa cgggtcgcta ataagtggtg
    25921 gatatgcttg ataatttctg tttcgtcaaa gtggatagga aaggccagtt tatcaaggaa
    25981 agcatcggcc tctgtaaaat caactccagg aataaagcca aggacttgca gggccagtaa
    26041 atcaaaaacc tctttggata actcttgctc tgattgaaaa aagctcaatg cgtccatgtc
    26101 atttttggcg attagatgac ttaaaggata atcactatca gggtagtgga agaagagttt
    26161 acgtaaaaag ctttctaggt tagctttggc agttttttgc agatccagat caaagcccaa
    26221 ttcttttaat tcttcagccg ctctttctag actagttgga atataggaaa attgattata
    26281 gcgcatagga gtttcctttc tagtggctta gaaaacgata ttatctttta atttatcaag
    26341 attggtaatg ataatatgtt gtttatcaat gcgaatgacg tttttttctt tcaactgttt
    26401 tagaatacgg ctgacgctgc tagcggtaga aatgccacag aatttaccga gttcctcatt
    26461 agtaatgaca aaattaatta aaatttgacc atttggtagt tcttcgccaa atagggtcat
    26521 taagtcatat atttgagtag aaatggcacc gatacggccg ttagttaaca tacattgcat
    26581 ttttttcatg gatttttgaa gacgattatg gtaaaagtcc ttcacatatc cttgtagttc
    26641 aatatcttcg tttatatctt ttaaaaatgc tgagcggcga accttgtaaa aactagcttt
    26701 ctctgactcg atgcgaacat tataaggctc tcccatatct tttgaataac cagtgttgag
    26761 aacagaagta atttcaagtc ctgtaacata tctcaaatta aattccattc catattttga
    26821 aagagcactc tgtttcacaa tgccgtcttt taaaatataa gtgaagtcct cttcgagact
    26881 ttcaaaagtc aagtacttgt gataactttt ttcaatgata ggaaagttat gattatcaat
    26941 ataccgttgc aaaatgtgat gattcacgct tttctccaaa tattctttta ccaatgtata
    27001 atttgtatct tcaagagaaa ttaacatttg ctaatgccct ttgatagtaa cacttatatt
    27061 ataccattga aatatattat attctgcttt ttttgtaaaa tgtttatgaa aatagagagg
    27121 agttcatttt caatggaaga aaaattgttt aacaaacatt ttgtggccat cacagtaata
    27181 aactttatag tctatatggt ctactatctt tttacggtta ttattgcctt tgtggcgact
    27241 agagagctag gagctcagac tagccaggca ggattggcaa cagggattta tattctaggg
    27301 actttattag cccgtttgat ttttggaaag cagttggagg tatttggtcg tcgtttggtt
    27361 ttaagaggag gtgctatttt ttacctctta acgaccttag cctactttta tatgccaacg
    27421 attagcatga tgtacttggt tcgtttctta aacggatttg gttatggtgt ggtatcaact
    27481 gcgacaaata ccattgtaac agcctatatt ccagcttgta aaagaggaga aggaattaat
    27541 ttttatggct tgtcaaccag tctagcagca gctattggtc cttttgtagg aacctttatg
    27601 ttggataatc ttcatattga ttttcgcatg attattgtat tatgtagcgt cttgattggg
    27661 tgtgtggttg ttggtgcttt tgcttttcca gtcaaaaaca tgtctttaaa tgcggagcaa
    27721 ttggctaaaa ccaaatcgtg gactgtggat agtttcattg agaaaaaagc cttgtttatc
    27781 actgcaatcg cctttttaat ggggattgcc tatgcttcag ttttaggatt tcaaaaatta
    27841 tacacgtctg aaattcattt gacagcagta ggtgcttatt tctttgtggt ctatgcctta
    27901 atcattacca tcactcgtcc agcaatggga cgtttaatgg atgctaaagg cgataaatgg
    27961 gtcttgtacc caagttatct ttttttagca atgggactct tcttgctagg tagtgtatcg
    28021 tctggaggaa gctatttgct ttcaggagcc ttgattggct ttggttatgg cacttttatg
    28081 tcttgtggtc aagccgcctc catacaagga gtggatgagc atcgctttaa tacggctatg
    28141 tctacttata tgattggtct tgatttaggt ttaggtgctg ggccttacct cttgggcttg
    28201 attaaagatt tggcacttgg tagtggtgtg gcttccttta ggcacttatt ctggttagct
    28261 gctgtgattc cactgatttg taccttgctt tacttgttaa aaacaaagac aagacaggtt
    28321 gtgtcttaag gacaagaaaa ggagtttagt cttatactta aatacaaacg tatcttaaca
    28381 gctgtagata gttcctatga gccgggatta gctgtgggta aagccattac tgtagcgctt
    28441 tgaaataatc ctagtttgct attggtacat gtcaataaaa atgactcgca aaagccattc
    28501 gtgaaagaga aagtgtggcc ttatttttag taggtgcaat tggattaaca tcagaatata
    28561 ggctttgtca tgttaagatt gatctgttga tagtgagagc taataaaaaa tgttataata
    28621 ctatgaaata aagtgataaa gataaggcct tttatggtcc ttttctttac cgcttttatt
    28681 attgtgtgaa aataacactt aatgatcatt ttatttatta ttttattacc tttacattca
    28741 tcaataagcc tgttaaaatg gtatttgtta tattttatta tttggaggaa accagaaaac
    28801 atggaaatga catggactgt gaaatacatc acagaattta tcgctacggc ttttttgatt
    28861 attttgggga atggagctgt tgctaacgtc gacttaaaag gaacaaaagg acataactca
    28921 ggttggttag tgattgcttt tggctatggc ttaggagtta tgatgccagc tttgatgttt
    28981 ggtaatgtat ctggaaacca tattaatcct gctttcacag ttggactagc agtatcaggc
    29041 ttgttcccat gggctcacgt cttacaatac gttgtggcac aattacttgg agctatcttt
    29101 ggtcagttgg tagtggtaat ggtttataaa ccttacttta tgaaaactga aaatccaaat
    29161 catgttttag gctcattctc aacgatttca tctcttgata atggtcaaaa agacagccat
    29221 aaagcctctt atatcaatgg tttcttaaac gaatttgtag gttcatttgt tcttttcttt
    29281 ggtgctttgg ctttgactaa aaactacttt ggggtagagt tagttggtaa attgattgaa
    29341 gcaggttacg accaaacaac tgcagcaaca caaatttcac catacgtgac aggctcattg
    29401 gcggttgctc acattggtat tggtttctta gttatggtct tggttacttc attaggtgga
    29461 ccaactgggc cagcactaaa cccagcgcgt gattttgggc ctcgtttgtt acaccacttc
    29521 ttaccaaaat cagttcttgg tcaagccaaa ggtgattcaa aatggtggta tgcatgggtt
    29581 cctgtagttg cacctatctt agcggcgata gtagccgtag cagcgtttaa atacctttat
    29641 atcagataaa aaaagaacta aagcttcttt tagactcaag acaagctcgc ttaaggaact
    29701 tgtctttttt atatgagtta agcgaaatct aatgcaaact tgactgtctt gtatagcgta
    29761 ttttgtaaat tttactagac ttcttgtaaa aaagcctctc ctcagataag atgactaatg
    29821 cctctaaacg gtgttacaaa taaacgaggc atccctaact tcctttatct ggtgttgaaa
    29881 ctattttgca cggactaaat cactgataga gtaaaaaacg atttttcatt tttgttgtaa
    29941 aatattaaaa acgtctctgg ttagtgattc ccagaaacgt tatcttatct atttgtttgt
    30001 tgcttatgag aggtaaagga ggaacgaatc agcattccac cagtgaagaa aacgatagcg
    30061 atgaccagaa gtttcaagct attaatatct aaattcgtta agaaaaacac agctagtaaa
    30121 acgccaataa taccaccaga aacaattcca gcaaaaccat cccaactgac acggtttgct
    30181 ttgataaact ggctactaga agctgtcata atcatagctg catctagcat cataacaggc
    30241 atagcaactg ttgggctaag acccattaat gaaaagaaaa tcaattctgg agcataattg
    30301 cctaacccca tagtcatcaa gactccaacg ataaaattaa aaccaattcc aacaaaaagc
    30361 cagatgccat ggaggccatg aatggtgtct gaaaggtgtt ctcctggatg gtagattatt
    30421 ctaatgatca tgattatagc tgctatgatt aaaagactac caaggattcg ttggacagtt
    30481 ggagcatgcc agttttttgt aatatgagtc ccaaaataag ctccaataaa ggctgctgca
    30541 gccatagcaa gtaaagttag aacctcaact tttacgacaa aaataaagca aagagattga
    30601 atgagcaccg gaagcacatg agctacggtc atagtgccag gcaattgtct atcgtcagtg
    30661 actaatttag ttaacttaaa gcacgttgtg gtagtagcaa aagaccctat cccaagggtg
    30721 tcaagggcat ctgttagcag accaatccaa aaccccgtcc aaaagcgttt aaaaggattg
    30781 atcttatttt ttttaagatg ttttactaac ataaagaaaa taaaaagcat tgccgaaact
    30841 agcaaagctt gtatcagtct aaggataagc atttcgttca taaagactag tttacaaaaa
    30901 aaaaccttag ccgtcaacgt gatttacttc attaaaacat gccactatgc ttggaagagc
    30961 tttggttcga tatattttgt taaaattaag ctaaaatatt aatattgcat gaaaggggac
    31021 gccttccttt ttcccttact gagcttagct gttattgtag tgaatgttta aaaggctagt
    31081 ttgtcgctct ttatcaaaaa tctagtagga tgaatacgta taatttcttg tcaaatagag
    31141 gaattttgtc tataatagca gaggattagg aggaaattat gactttaatg gaaaatatta
    31201 cctttaaaac tccagtatta cgcgttaatg atcgcgacct taatattgca ttttatcaaa
    31261 ataatttagg gcttcgttta gtatctgaag aaaatgcggt tgctatcttt tcatcttggg
    31321 gagaagggca ggaatgtttt gtaattgaag agtcaccttc agttagaacg cgtgcggtag
    31381 aaggccctaa aaaggttaat acgattgtca tcaaaacaaa tcaacctaaa gaaatcgaac
    31441 aattattagc tcatggagca cattatgata ctctttttaa aggtcaaaat ggctatgcct
    31501 ttgagactat ttccccagaa ggagaccgat tcttgttgca tgctgaacaa gatattaaac
    31561 atctccaagg tactgattta ccatcgcttg aaaaagatgc gacttttaaa ggtttaactc
    31621 aatttaagtt tgatattatt gttttaaatg ttattagtga agaacgctca aaagcttttt
    31681 atcgggatct gtttagtgat cagttaccta ttactatgga ttttattcaa gaagaaggtc
    31741 ccgatttggc aattgatccc catattgctt gggatttaga aattttagaa tttcaagtct
    31801 caaaggacta tgatatgaag gtcctaaaag caactttaga agaagacggg cacaaggtct
    31861 acattgataa aaaacacaaa gtattggtcc tttctgatcc aagtcagatc gaagtatggt
    31921 ttacgaaatg actttggcag tcattaaatg tattgaaaac catcttcaca aaaaagtata
    31981 caaaggggcc agtctggctc tctttcaatc tggtcgatgg caagaatacc atatcggaac
    32041 aattgatgga agacgaccag ttgatgctaa cttagtttat gacttggcta gtgtttcaaa
    32101 agttgttggt gtggccacaa tatgcaatat tttattgaat aatggtacgt tagcattaga
    32161 tgatccctta aaagtatatt atcctagtat tgctgatacg actgtcacta ttcgacagtt
    32221 attgactcat accagtggtc ttgatcctta tattcctaac agagatgttt taaatgcaca
    32281 acaattaaga aaagcactta atcatcttac tcaaaaagaa aataaaaact tttattacac
    32341 agatgttaat ttcctcttgt taggctttat gttagaagag ctctttagtg aatctttaga
    32401 ccagatattt gataagacta tctttactcc ctttgggatg tatcatacgt cttttggccc
    32461 tcgtccagaa gctgtaccaa cattaaaggg tgtgagtgat ggagaagttc atgatcccaa
    32521 agcaaaaatc ttaaaaaaac attctggatc tgcggggcta ttttcaactc ttgcagattt
    32581 agaaagtttt agcaatcatt atcttaatga tccattttca gattgtctgt ggcgcaacta
    32641 cagccaacaa acaattgagc ggtcactagg gtggaattta gatggcgatt ggattagtca
    32701 tacaggttac acagggccgt ttctaatgct taataaaaaa gagcaaacgg cagctatttt
    32761 tttgaccaac cgtacttacg acgaggatga taaaagtaaa tggttaaaag aacgtcagtt
    32821 gctttacaat gcactaaagc atgatctgac aacacccgta tcgtaacgtc taaaggggca
    32881 gttttagtga tcttattact gtttttaaag tttcttctaa aaaatagcca tttcatttgt
    32941 ctgatgcgat tagagtgatt ataagtgaaa aaagaacagc catctcattt tgaatcaaat
    33001 gagatggctg ttctttttta taagttattg atcatttaga tactactatt tacttgaaat
    33061 agcttcagcg gcatcatcca ttgaaagcac ttcgtggaag acacgttgag tcaattcagt
    33121 tttttgttct ggtgtaaggt atttggtgtt gacacagtaa ccagagatac gcacgataac
    33181 gtcttcgccg ttcatgattt tgtcataaac atcgttaagg tccataacgt tcaagttaac
    33241 gtgttgacca ccattttcaa agtaaccgtc aagcactgtt accaagttgt caacttgttc
    33301 gtcaaatgtt ttaccaagag cacgaggtga tacttgagta gtcaatgaga taccatcgtt
    33361 agcatgtgag aattccagtt tagcaagtga gttaaggttt tgtaaccagc caccttttgc
    33421 tttgttagat gggttagcac ctggtgagaa gaattccact tggctagtgt taactgtacc
    33481 atcttcgttc aagaagacgc cgcggtgaac tggagagtta ccagtttgtt tagagtaagc
    33541 aacgtttgaa gtgatggtaa gaagtgatac tgaagcctca gcattcttgt aaagtttgtg
    33601 gcttgcaaga cgtgtgtggt aagcttccat caaccatttc gcgatgtcat caacacggtc
    33661 gtcatcttca ccgtaacgag ggaagtcacc tgttacttcg tagtcataaa tgtagccatt
    33721 ttcatcgcgg atagttttaa cagttgcgta tttaatagct gacaaggtat caactgtgtt
    33781 agcgaaacca cagataccga atcccatgtt agcacgttgg tgtgttggca agaaggccat
    33841 ttgaactgct tcgtagttgt atttatcagt catgtagtgg atgatgttaa gcgcatctac
    33901 ataagtatct gtcaaccagt caagagattt ctcaaagtta gccataactt cgtcgtactc
    33961 aagaacttct gatgtgattg gttcaacaac gttaaacact ttgtagtctc tgtgaacatc
    34021 atcgtaacca ccgttaagac cagtaagaag ggccttaaga acgtttacac gagcaccgaa
    34081 gtattggatg ttatgacgtt gttcttcatt ttctgggtca agtggtgata cacaacatga
    34141 aatacatgac atctcaccat aaccttcttt agccattgtt gtcacacctt catattggat
    34201 agaagagtgt ttgtggctca ttttcataca gtagcgacgg aatgtttctg gcagttggtc
    34261 agtccaaaga actgttaagt ttggttctgg agagttaccg atattatcaa gagtgtttaa
    34321 gaaacggtag tccatcttag ttacacggtg acgaccgtcg ttacccatac cagccataga
    34381 agttgtgatg aatgttgggt cacctgagta aagggcatcg taagctttcg tacgaccaaa
    34441 ttttacggta cggagtttaa ggacaaaatc atcaacaaat tcttggattt ctgattctgt
    34501 aaaggtaccg cgagcaaggt cacgttctgc aaagatatca agaacgattg gcacacgtcc
    34561 aagagaagta gcagcaccgt tgatcacacg acatacagcc atgaaagcga tgtttaccca
    34621 ttggatagct tctttaacgt tttgtgctgg gcgacgaaca tcaactccgt aaaggtcacc
    34681 aagtttaacc acttcaccaa gagcttggta ttgaaggtta acttcttcgc gaagacgaat
    34741 ggattcttca tcgatttcag tgatagcatt ccagtcattg actttttctt gcatcaagta
    34801 gtcagcaccg taaagagcaa gacgagcgta aacaccgatg atacgtccac gtgagtaagc
    34861 atctggaaga ccagttacag tgtgggcatg acgagcacga cgaatatttg aagtataagc
    34921 gcggaagata ccgtcgttaa cagttgtcac gtacttagta aagatttcgt gtactgctgg
    34981 gtctggttca tagccgtttt ctttaagggt cgtttccgcc atacggatac caccttttgg
    35041 catgaagttc aatttgaaca attcatcgtt ttgaatacca taaattaatt cattttcttt
    35101 atcgatgaaa ccagcaggaa tgtcagcaat tgaagttgga cgagtatcgt atgggaaacg
    35161 tgtagcttca tagtgtgctt ttgtttcttc gataactttt ttgatgtgaa gtgaacgttc
    35221 agtagcacca gccaagaaag attcatcgcc atcgtatggg gtgtagttag cttgtacaaa
    35281 acgtgagaca cttgcttttt ctttccagtc agttccttta aagccttccc aagctttttc
    35341 gaaaacatct gtattggttt taacagttgc cataaatttc tccttaaatt ctagtaacaa
    35401 agcgatctgt tacatttaca attctaagtt taacacatag gaaacgtttt cccaagcaaa
    35461 attcttgaca aaattaagat tcttttataa tacagattgt tgaaacagtc acaaactgta
    35521 ttagaatgta tttttttggc tttagatagc ctaaaaggta taatagagaa aggagggact
    35581 tatgcttatt tttccactga ttaatgacac gtcacgaaaa atcatccata ttgacatgga
    35641 tgcctttttt gctgcagttg aggaaaggga taaccctgct ttaaaaggaa agcctgttgt
    35701 gattgggaaa gatccaagag aaacaggtgg tcgcggagtt gtttccactt gtaattacga
    35761 agcgagaaaa tatggcattc attcggccat gagctctaag gaagcttatg agcgttgtcc
    35821 caaagccatt tttatttcag gaaattatga aaagtatcga acagttggag accagatccg
    35881 ccgtattttt aagcgttata ctgatgtggt agagcccatg tccattgatg aggcctatct
    35941 agatgtcacc aacaataagt tgggtataaa atcagccgtc aaaatagcca agctgattca
    36001 gcatgatatc tggaaagaag taggattgac ctgttcagca ggtgtgtctt ataacaaatt
    36061 tttggctaaa ttggctagtg attttgaaaa accccatggc ctcaccctag tcttgaaaga
    36121 agatgccctg tgctttttag ccaaactccc cattgaaaag tttcatggtg ttggtaaaaa
    36181 atcagttgaa aaactgcatg acatggggat ttatacagga caggatttgt tggcagttcc
    36241 tgaaatgacc ttgattgatc attttggtcg gtttggtttt gacctttacc gtaaagcgag
    36301 aggcatcagc aattctcctg tcaagtctga tcggatacgc aagtcaattg gcagtgagag
    36361 aacctacgct aaactgcttt atcaagaaac agacatcaag gcagagatca gtaaaaatgc
    36421 taagcgcgtg gccgctctct tacaagacca taaaaagtta ggcaagacca ttgtgctcaa
    36481 agtgcgttat gctgatttta ccaccttgac aaaacgtgtc accttgccag aattaaccag
    36541 aaatgccgca caaattgagc aagtagctgg ggatattttt gacagcttaa gcgaaaatcc
    36601 tgctggtatc cgcctgttag gggtaaccat gaccaatttg gaggataagg tagctgatat
    36661 ttccttggac ctataggaga aagagtgctc tatccgtccg cctcattttg gagaaaaaag
    36721 aagctgatta gggatttccc taatcagctt ctttggtcca ttattttatt acagcatagc
    36781 ttggtctgta tcatcacctt tttcgttaag ggttttagcc ttgtaaaaag caaagccata
    36841 aagagcagct tgtataagga taaggatagt tccaaccatt gacatggttg ttgtgaactg
    36901 gttaaccaag ccgataacag aaaggataag gcctaagata taaggaatat aactaaccgt
    36961 tagaccttgt tttaatttag ataagttttg agcacaaaag acaatgatag caataatagc
    37021 aaggacattt aagacagata agaaaatcat aaatggtgtc atgctgcttt gtagctgtgc
    37081 caattgctca gttgttaatt gggcccgaaa tgcttcattc ttgagttggc tttgtaagta
    37141 gaaaatccct gcaaatccca ttaatgacag tacaactcca agcccgttta gaataataat
    37201 ggcaatagta gacgttttga gtgcctgacg cactttttca taagaaatca tataatcctc
    37261 ctagagtcct taatccgaaa ttgtacaatg tgtttaatac aaaaatatta taccatagat
    37321 taatcaaaaa tgtccgtttt tctaggattt tttctggaaa aagagggcaa tatctgactc
    37381 tgtaagccct atcatcgaat cgatagtcga ataattctca ggtgttaacc taaaatcatc
    37441 attatctgac tgagagttct cagtggggtt agagtttgtt gattgagagg aagatttttg
    37501 agagtcgtcc tcaagggttg ccgtattaga aaaaagggag gtctgctctt ttgattttag
    37561 ctcttggtta ggttgagagg aggctaagtc ggattgttct tggaagcgtt cgatcaagta
    37621 ggtttggcgt ttatcgcctt cgtgtttaat agcatactca aaggcagtat attctcccaa
    37681 cagaattaac ttacttttag accgagtaat ggccgtgtaa atcacatttc gttgcaagag
    37741 tcggccgctt tggcgtgtga taggtaaaat caccacttga aactcactcc cttgcgattt
    37801 atgaatgctc atggcatagg ccagggttaa ttttagccat tcatttctag ggtacgtgac
    37861 ttcgctaccg tcaaaatcta agattaattc gtcttgctta gattcggtgt atttagcagg
    37921 aatcaaatct gtaatataac caatatctcc gttaaagaca ttcaactgag catcgttgac
    37981 taagtgcagg actttatcac ctttacgaaa atacgtatca ttgaacagaa attctgtttg
    38041 tccttgcaag ggattgagaa gttcttgcat gagttgatta agatgattga tgccagcttg
    38101 tcctttgtac ataggcgcta aaatttgaat ttcctcagca gggatgccac ttttaatagc
    38161 agataggaca attttttgaa tcatgtcagg gataaaggct gcttgggctt caaaataaga
    38221 acggtcagct tttttatcac gaaagtcagc agctaagatt cctcgacgca tctgatctgc
    38281 caaattgaca atagtagatt cttgggattg acgaaatatc ttttgcaagg cgatttgggg
    38341 caggctattg acttttaaaa gatctgacag gacttgaccg ggtccaaccg aaggaagctg
    38401 gtcactatct ccgacaataa tcacttgagt tgttgagtta atagctccta acaactggtt
    38461 ggcaagccag gtatccacca ttgaaaattc atcgacaatc agcaagtcgc agtctagata
    38521 atcctccatg gcttggtaat cgttgtcgcc attgaggcct aagtgcctgt ggatggttgc
    38581 gctaggaagt ccagtcaact cattcatgcg acgtgcagct cgacctgttg gagctgctaa
    38641 caagatagga aggtcttttt tatccaaatc aatctgatgc aggttcgcgt aagcctgcaa
    38701 aatgcctcga ataacagttg tttttcctgt tccgggacca cctgttagga gaaagacctt
    38761 gctggttaag gccttagtaa tggcttcttg ctgcacttgg tcataggtga tggcaaagtc
    38821 tttttgaacg gcttggatgg ttgtttgaat ggtatcatga ctaaatgact gacttaaagg
    38881 ggtatctaag agacgagaga tgttgttagc aatcccttct tcagcaaaat aaaggctagc
    38941 atcaaacagt ttggtgtcac tgtttttgat tttgccctct atgatcaact cgcttagttg
    39001 ttcagccaca gcagcaggat cacattctaa ttgacgtgca tcttcaagga gtgtaatggc
    39061 aaagtctaat aattgtcgtg cttggacata agtatctcct cgattgatgg attcttccaa
    39121 gagacagtga aggagggctg cacgaaaacg tttcggagag tcgctttcaa tccctaagtt
    39181 ttcagcgaga gcatctgcca ttttaaaccc aaaaccttgt agatcttcga ctaactgata
    39241 gggattttct ttaacaaggt caagagcctc ttctttatac ttttcaaacg cttgaaaggc
    39301 aaaacggttg ctaaggccaa gttcgacgag accagcaatc agttgctctg tgccgtaatt
    39361 caattttagt ttagcgacaa aggcttgacg attagcctta gataggccag agatagtttc
    39421 taatttgctt gggtcttcta aaatatggtc aatggtatta tgaccatata gtgcaatgat
    39481 tttctccgct gtttttttac caatcccctt aaaatggtca ctagagaaat aattaaccaa
    39541 accagatgaa ctaggtttga ttttttggta acggcttagt ttgagttgtt gaccgtattt
    39601 agggtgctgg gtcaattccc cccaaaaggt gtagtcatct ccttcaataa tgtcagccat
    39661 cgttcctgtg ataatgattt caaagtcgtc aatgtcactg tctgtatcct caatggcaag
    39721 gaggagaatt ttaaagaaat tagcctggtt ttcaaaaatg atacgatcaa cagtacctgt
    39781 aaaaacgtat tccatagtaa ctctttctat ttatacaaga taactgaaaa cctgcccaaa
    39841 ggcaggtttt ttctaattaa agacggtcat tttattgagt ggccaaaaac gagctttcac
    39901 ttcaccgata aggttttctt ttttgaaact accaacttcg cgactatccc tggaaacaat
    39961 acgatcatca ccaagaagaa ggtattctcc ttttggaaca ctcatctcaa agcgtgtttg
    40021 tccctcagaa ttagttgtaa aagcatcaga tgtttctgct aactgttgga atagggtatt
    40081 ataggcgtaa gttttttgga gtttatcgtt tttaaattgt tttagatact cagccaaata
    40141 cggctcaact gtttttttac cattaatata aagtgtgtca tcattataag aaatggtatc
    40201 gcctggcaat ccaataactc tttttacgat ttctttcttt tgtccgtttt cttcttcctg
    40261 agcaactaca atatcaaagc gatcaatcct agcttgatta aaaacgataa ggcgttcgcc
    40321 atgagctaga gttgggtcca tagaatggcc gtctacttta acagcctgcc acaaaaaaag
    40381 acgagataga ccaaagagaa ttaaaaagag agtgaatggg ccccattctt taataaactg
    40441 tttcatatga ttccttttat ttagtgagaa gcgcttgcgc tttgtgagtg ttggcgaagt
    40501 gaagtttagc actatattct aagctagaca taccataagc ggctaagagt tggctagcaa
    40561 ctttatctga agctgaacca gcaccgcttg ggagttggta acctaaatct tgacctaatt
    40621 gatcgagatt gtctaaaaat agatttctag caatgataga gctaacagcc acagccaaat
    40681 agtgactttc tgccttttct tgaaaggtta gaggatttgg gaaatggttt ttttcctttt
    40741 ttagatgctt ttcataattt gattggctag tgaaagcatc aataacaatt tgtttaggtt
    40801 gaatgccttt ttgtaacaac aaaaaaatag cttggttatg aagagcaact ttgatagaaa
    40861 tggcattata tggtttactt ttaccaacca attcgttata ttttttaggt gataggagaa
    40921 gtgattgatg aggtatttgt ttctctaaca gaggcgcaat ctgttgaatg gttttatccg
    40981 ataatttttt agaatcatca accccaagct ttttcaggaa ggaatgatct ttaggatcga
    41041 caaaacttgc cacaacagca atcccaccaa aataagagcc attacccacc tcatcactgc
    41101 cgattatagg tatatcttgg ctattgttgc ttgcttcaaa aactgtctta gctactggaa
    41161 gattaagctc ttgagctaaa gcatttgcac cgtttccctg gagaactaat tttccggatt
    41221 tgtacagcaa aacagtaacc ccattttttt tagcagcaaa ggctacatag gtattttggc
    41281 tactgatggt gtagggggct agctgttttt ttaaatgttt actcagtata gcatctattt
    41341 tcaaaactaa ggtattcata ataattattt taacataaaa tagttgacta tggttaattc
    41401 ataagtttat ttaacaaaga aaacagagac tcgaatgttt agacgggtta gggcaatggt
    41461 gttgactatt ttacgaaagt ttcattttac ggtataatgc taatgaggtg accctatgaa
    41521 aagtattaat cgctacaaat tcacctttgg tgaaaaaaca ttaacattga caactgacaa
    41581 agacaatctc tttatggaag aagttgagcg ggtagctaaa gaaaagtatc aggctcttaa
    41641 aaatcattta ccagaagctg atgacgagac tatcgctatt ttaatggcta tcaatacctt
    41701 gtcaacacaa ttaagcagag aaattgccat tgaaaaaatg gaagctgaaa ttttagattt
    41761 acgtcaaaaa accttggttg gtcttcaaga aaaagctaat caaatagatg tgaatgaggt
    41821 ttaatcatgt tatctttatt gatagtgctt gttttaactt ggaattttta tattggttat
    41881 agtagaggta ttattcttca atcgttttat gtcttaggag ccctactttc tcttttggta
    41941 gctaatcgat tttatattgg attagcccat aagctaacgc tttggattcc ttattctaac
    42001 cctgtagaag gaacatcagt ctttttcttt aaatcagttg atatctttgt tttagataag
    42061 gtttattatg caggccttgc cttttttatc attttcttat tggggtatgc attgagtcgc
    42121 tttcttggga tttttgttca tttccttttg ctagattatt ttgataacca gtggacaaaa
    42181 tgtttgagtg gcggactagc gcttctagta tcgcttcttt ttttgaacat gttactgtct
    42241 atttttgcaa cggtccctat gcctttttta cagcactatt tgcactctag ttttcttgct
    42301 cgtttggtga tcgaacacct tccaccattg acaataatta ttcaaaaatt gtggatgcaa
    42361 gccattattt gatatcgttt tgtgactaat ataagaacct ggagtgagtt tcacctttag
    42421 gttctttatt tacgagaaac tgtttagaaa taaagagaac gcatgggaac ttagtgactt
    42481 tcttgccaca ttttccatca ttttaggtat aatgaagagt atgaataaca agattttaga
    42541 gcagttagaa tttaacaaag ttaaggaatt gctattacct tatctcaaga cagaacaatc
    42601 ccaagaagaa ttattagagc tggagccgat gacggaggct cctaaaatag aaaaaagttt
    42661 taatgaaatt tctgacatgg aacagatttt tgttgaacat cactcatttg gcatagtcag
    42721 cctaagttca atctctgaga gtttaaaacg cttagaactt tcagctgatc ttaatattca
    42781 agaacttttg gctatcaaaa aagttttaca gagttcttcg gatatgattc acttttattc
    42841 tgatttggat aatgtttctt tccaatcttt ggatcgtttg tttgaaaatt tggaacaatt
    42901 ccctaatctg caagggtctt ttcaagctat caatgatggt ggttttttag aacattttgc
    42961 gagtccagaa ttagagcgta tccgtcgtca attaacaaat agtgaacgac gggttcgtca
    43021 gattttacag gatatgctta aggaaaaagc agagctttta tcagaaaatc taatcgctag
    43081 tcgtagtgga cgaagtgtcc taccagtaaa aaatacttat cggaatcgta tttctggtgt
    43141 ggttcatgac atctcttctt caggaagtac tgtttatatt gagcctcgtg ctgtagttac
    43201 actaaacgaa gagataacgc agcttagagc tgacgaacgc cacgaagaag gtcgtatttt
    43261 acacgcattt tcagacttgt taagacctca tgtcgccact attagaaata atgcatggat
    43321 tcttgggcat cttgattttg taagggctaa atatcttttt atgtctgata ataaggcgac
    43381 gatacctaag atttctaatg acagcacgtt agcattaatc aatgttcgtc atcctctttt
    43441 aagtaatcct gtggctaatg acttacattt tgatcacgat ttaactgcaa ttgtcattac
    43501 tggtcccaat actggtggta agacgattat gctaaaaaca ctcggtttag cacaattaat
    43561 gggacagtct ggtttgccag tattagcgga taaaggtagt aaaattgcag tatttaacaa
    43621 tatctttgca gatattggcg atgagcaatc tattgaacaa agtctatcaa ctttttctag
    43681 tcatatgacg cacatagtca gtattttaaa cgaggctgac cacaatagtt tagttctctt
    43741 tgatgaacta ggagcaggaa cggatcctca agaaggtgct agtttggcca tggctatttt
    43801 agaacacctt aggttaagtc atatcaaaac gatggcgacc acgcactatc cagaattaaa
    43861 agcttatggg attgagacaa attttgtaga gaatgcgagc atggaatttg atgcagaaac
    43921 gcttagcccc acatatcgct ttatgcaagg agttcctgga cgctcaaatg catttgaaat
    43981 tgcttctcgc cttggtttag ctccatttat tgttaaacaa gctaagcaga tgacagattc
    44041 tgactcagat gttaaccgta ttattgaaca gttagaggca cagacacttg agacacgtag
    44101 aagactggat catattaaag aagttgaaca agaaaacctc aaattcaatc gtgcggttaa
    44161 gaaactctat aatgaatttt cacatgaacg cgataaagag ttagaaaaaa tctatcaaga
    44221 agctcaagaa attgtagata tggctttgaa tgagagtgat actatcttaa aaaaactcaa
    44281 tgataagagt caattaaaac ctcacgaaat tatagatgct aaggcacaaa taaaaaaatt
    44341 agcgcctcaa gttgatttat caaaaaataa agtcttaaat aaggctaaaa aaatcaaagc
    44401 agctcgtgcc cctagaattg gtgatgatat tatagtgact agctatggac agcgaggtac
    44461 cttaactagt caattaaaag atggccgttg ggaagcacaa gtgggaatta tcaaaatgac
    44521 attaacacat gatgaattta ccctcgttag agtccaagaa gaacagaaag tcaaaaataa
    44581 acagattaat gtggttaaaa aggctgatag ttctggacca agagctcgac ttgatcttag
    44641 aggtaaaaga tacgaagaag ctatgcaaga gttagatcat tttattgatc aagcattgct
    44701 taacaatatg ggacaagttg atatcattca tgggattggt acaggcgtta tccgtgaggg
    44761 agtgacaaaa tatcttcgtc gtcataagca tgttaagcat tttgcttatg ccccacaaaa
    44821 tgcaggggga tctggtgcca caattgtaac gttagggtaa atgatggaat catatgaaca
    44881 cttttatgcc aaactatctc aaccttttag aaaatcccca cagttaataa ttcttttaaa
    44941 tgttttacta aaaataatca cagcaatgat gtacatactt tatccatctt ttctgatatt
    45001 tacgctttgg caagggatga catttcaatt atggttaagg ctattaatta ttccttctgt
    45061 tggatttata gctttgtctt acattaggaa acgccttgat tttccacgac cgtatgaaaa
    45121 atggaatatt aaacctttaa ttgataagga tacaaaggga aggtcaatgc ctagcagaca
    45181 tgttttttca gctacgatga ttagtatgtg tttgttacga tattatgttt actttggaat
    45241 agtttgttta atattgtcgg ttttattggc aatttgccgt gtgatagcag gtattcacta
    45301 tcctaaggat gttattgtag gttaccttat tggcttgatg ttagggcttt gtttattgat
    45361 ttagcgagtt cgtagcaaat agtttcaaaa acaactaaat tcttgtacaa taggcttatc
    45421 attaagatga aatggagaaa aaagatggca ttagaagtaa cagatgctac atttgtagaa
    45481 gaaactaaag aaggtttagt actcattgat ttttgggcaa cttggtgtgg tccatgtcgt
    45541 atgcaagcac caatcttaga acagttatct caagaaatcg atgaagatga actcaaaatt
    45601 ttgaaaatgg atgttgatga aaatccggaa actgctcgtc agtttggtat tatgtcaatt
    45661 ccaacattga tgtttaaaaa agacggagaa gtggttaaac aagttgcagg tgttcatact
    45721 aaagaccaac tgaaagctat tattgctgaa ttgagttaac taaaataaag cccagcgtca
    45781 cgctgagctt tattttatga cctactaact tcaatggaat aaccatgtga acataaaacg
    45841 acttgcaaaa gcaatagcaa cagtaatgag gaaaaataca gtgacaataa gggggttctg
    45901 ataaggaagt tttgctcttt cttcccgttt ttcgatttcg tctaataatt ttccatttga
    45961 aacagctagg atttccttat aaggttgcac atcatatttt ttcttaaaac gttccacacg
    46021 attagcataa gtcatagtaa ttatcgataa taaaacaaaa atgccaaatc ctagccactc
    46081 taagaaatag actaatggat aacttgaaat cattaatagt atcatcaatg ttaccattac
    46141 tttggtatct cgttcaaaat tctttttatc aacctgagtg atggtatatt tcattttctc
    46201 aatgtctcct ttaatgagtt ggtttaagct cacttgaaaa atttgactta ggagtaagag
    46261 gctatggatg tctgggtaag ttttgtcatt ttcccagtta gatatgctct gacggcttac
    46321 atagactttc tcggctcata atattagtat aagaatgata agctaacggg tctatcaaat
    46381 gtatttgaca ttagggatag atcactattt ataaggtatt aaaagacaat ctgaggaaaa
    46441 ctttacagcg gcgtaaagga attgtaaaca aaaagtgaac cgtcatagtt cacttgtgat
    46501 taagcatttt tctgttttaa gtaggtctct agcattttct tttgtggtgt tgcaaaggga
    46561 tacagagaaa agtcctcaat tgctacccac tttaggtgag gagcattagg taaatctgtt
    46621 gctttgacca ccccctctat gagttctatt gtccacttct ggtgactaaa agtgtgctta
    46681 atatttggaa agtgattatc agtccattgt ggctttaatt gatattctct ttcgaaagtt
    46741 tcattttggg tttgccagat tatggggttg gattgattgt catcaaataa atctaattgt
    46801 tgagaaagag gtgacgtttc gataatagga aatgaccaaa aacctcctag aagtctccct
    46861 ttagtatttt tctccagtag atattggcca ttttggttac gaatgacaaa agcctgaatt
    46921 cgcattggtt taggcttttt ctttggattt tttatgggat atttaccata agtaccattc
    46981 aaataagcag cgttaaagaa acgaataggg ctttcatcag gcctaggtgt cttagcggac
    47041 tcgatgtctg tacctagatc cataagtgcc tggttaaaat caccgggtct gtcagggtca
    47101 attagtattt ccataatagc ttgaaaaatt ttacgatttt tagggtcacc gatatcataa
    47161 ttaacttcaa acaaacgagc catgacacgc atcacattgc catcaacagc aggctctggt
    47221 aagttgaatg agatgctggc gatagcacct gcagtataag gaccaatccc ttttaatgaa
    47281 gcaatatcat cataagtgtg aggaaatatg ccaccaaaat caaccatcac ttgctgtgca
    47341 gccttttgca tattacgcac ccgagaataa tagcctagtc cctcccatgc ctttagtaat
    47401 tgttcttcag gagcgtctgc caaatctttt atttgaggaa accactctag aaaacgttta
    47461 taataaggga ttaccgtatt aacttgtgtt tgttgcaaca tgatttcaga aacccaaata
    47521 taatatggat tagtagttct tcgccaaggg agatcacgtt tttcttggtc ataccaccct
    47581 aaaagtgtgc gacgaaaaga agcgattgtc tcattatccc acatattaat accataatct
    47641 tttaattcaa tcatgttgtt attgtaacac aggagcctta aaaagagtaa aaaaagattt
    47701 taggtatttg cgaaaaagaa aaggaaatat tataataata ttaggtttac ctcatttaaa
    47761 tgttgattta gaataactga aattaacgat agaagcagac aggttttaat ttggagggga
    47821 catgttccag aaattaaaga atcttattga tcggtattcg tggttcgttt ttataatgat
    47881 gattcttgtg ttatttctta actatattta tccatttgat ccttctttga gcggactaca
    47941 gttggaatgg ctgatcatga cgcaagtttt tcctggatta ggtatcgtat gtgccatggt
    48001 tgctattatt tttaaaaagt ttaacctttt tgttttggcc ctaattttat attttgcact
    48061 ttggttaaaa cttttccttg ctttttcttt tttcacctat tttttaggag tctgactaag
    48121 tgccaatttt taaaactcgt gaaagaaaat gtttgacaaa acttagtcaa gtagaaaaag
    48181 ttccttgctt ttaattgact attagtgtac aataagattc tgtgagtata cctcacttac
    48241 tcactccaaa agtagtgagt cattagacca aaaggaggaa aatatcaatg gctaaatacg
    48301 aaattcttta tatcattcgt ccaaacattg aagaagaagc taaaaacgct ttggtagcac
    48361 gctttgactc tatcttgact gacaacggtg caactgttgt tgaatcaaaa gattgggaaa
    48421 aacgtcgtct tgcatacgaa atcaacgatt tccgtgaagg actttaccac atcgttaacc
    48481 ttgaagcgac tgacgcagca gctcttaacg agtttgaccg tctttcaaaa atcaatggtg
    48541 acattcttcg tcacatgatc gttaaacttg acgcttaatt ccaactaaga gggtagttta
    48601 tgattaataa tgtagtacta gttggtcgta tgaccaagga tgcagaactt cgttacacac
    48661 caagtcaagt agctgtggct accttcacac ttgctgttaa ccgtaccttt aaaagccaaa
    48721 atggtgaacg cgaggcagat ttcattaact gtgtgatctg gcgtcaaccg gctgaaaatt
    48781 tagcgaactg ggctaaaaaa ggtgccttga tcggagttac gggtcgtatt cagacacgta
    48841 actacgaaaa ccaacaagga caacgtgtct atgtaacaga agttgttgca gataatttcc
    48901 aaatgttgga aagtcgtgct acacgtgaag gtggctcaac tggctcattt aatggtggtt
    48961 ttaacaataa cacttcatca tcaaacagtt actcagcgcc tgcacaacaa acgcctaact
    49021 ttggaagaga tgatagccca tttgggaact caaacccgat ggatatctca gatgacgatc
    49081 ttccattcta gtcagaatgg attgaacgaa tacgaaatta tttgagttcg ggctaaaaat
    49141 ttagaactta gaatttagaa caactcccta ggaaatcaag atttcttgcc agttttctaa
    49201 aattcagtcg ttttttaaga gcccttaaca tcataattta taaaggagaa aatacatggc
    49261 tcaacaacgt cgtggcggat tcaaacgccg taaaaaagtt gacttcatcg cagctaacaa
    49321 aattgaatat gttgattaca aagatactga gcttcttagc cgtttcgttt cagaacgtgg
    49381 aaaaattctt cctcgtcgtg taacaggaac ttcagctaaa aaccaacgta aagtaacaac
    49441 agcaatcaaa cgtgctcgcg ttatggctct tatgccttac gtaaacgaag actagtaaac
    49501 aaacagtcca tttcggactg ttttttagtt gactaggact agtctaggcg tataggtgag
    49561 ttttttctaa aagagagaat gatagtaaac gaaaatcctt gcgtagacag caaggatgaa
    49621 atgattgtta tttgttaaca ggtgacatag tgttttgaat gttgtatttg cgttgtaggt
    49681 aatagcgtaa agcaagggaa acaccaccaa taatgagcaa ggcaagagga ggcaactgtg
    49741 ggttaagaga ggttggtaaa aaggcagttg cagagtacaa ggcaatccaa atcaacatgg
    49801 ctaatgataa ggctgcgatg attttgaacc aacttggacg aaggctctta tcttttccga
    49861 gatgacggta aataaagtaa taagtagcgt acatggatgc tcctccacca aaaccaagtg
    49921 ccagtaagga aatcaatcct gtaactgtag cgtttgtgtt gaagaaggtc atgatgccat
    49981 ttaaaagggc aacaattccg atgaatagca aagaggtatc tagccacatc aaccaaggat
    50041 tggtgttttt gtcagtttct gctgctcttt gactagggtc ttggctaaaa gaagctgccc
    50101 aagcagtcgg agtgcctaat agatttcgag cggtgacacc ttttttctgg ttttctagaa
    50161 tagctggaat ggcttcttcg agaatcagct taatatcctc atcagacttg ccgtcttgga
    50221 ttaatttgtt cgtagcggtg tggataaatt cttgattttt tttggtaagt tcttgtaatt
    50281 ccatgggaat cccttcttta tatgggttag ttaaagtaag tcaatggtat tagctagttg
    50341 taatgaaact ttggagctag ccgtttgaca cagagttttg tcaggtctta accgcattct
    50401 gcagcttgct ccactctaga accatttttt tctaataaag taaatcacaa caaaggaact
    50461 aagtagcata gcaatcaagg taatatacca aaaagcatgt tctaggccat ttagtggtaa
    50521 ccagttgttt tggaaattca taccataggc ggagaaaatc acagttggta tatctaaagc
    50581 catggtcatc aaggccagtg ttttcataat agtgttctgg ttgttgttga taatagaagc
    50641 agtggtttca gtcatggcat tcaagacatt ttcataaatg ccagccatct caatcgcctg
    50701 ttgggtttca atcaaggtat cttctagcaa atcctcgtcc tcaatgtatt tcttgagaga
    50761 gcttgttgag ctggataatt tcttgacgat gcgttcgttg aatttcaagg aagcctttaa
    50821 gtagacaatg gatttttcaa gttccatcat gtcgataagt tcttcatttc gagtagctgc
    50881 ttcaagctga gcttccaaac gttcgctttg gcgatcaatg gtcctcaagg cagtcagaaa
    50941 gagctcggcg ttgcgatata gaatctgaaa aacaaaacgt gtcttcatga aggtatagaa
    51001 atttttgacc cggcggttgt gaaaatgatc gaaaagggtc atgtcatgca gacaagttgt
    51061 gataacagca ttttccgtta caataatgcc taaaggcata gtaatatagt aacttttatt
    51121 gttacgttct tcgtatatcg ggacgtctac gataattagg gtataatcat cttctacggc
    51181 aatacgtgag gtttcttcca cgtccaaagg ggcgcgcaag tcagaaatat caatgttaaa
    51241 ttgatcggcg atcttcatag actcttcttg ggaagggtta accagtttaa tccaagctcc
    51301 tggctcgaat gtttctattt ctttgaattc aattgccgat gaaagaaaca tttgtttcat
    51361 gacaagccct cctttttgat gattgactgg tagagattga catcaaacct tgataataaa
    51421 gccttctcaa ggattttctg aaaaattctc aatacttatc tattatacca aaattcgcaa
    51481 agtttggggc aataggttat cagaaatttt tgttataata taaggttacc tctcagaacc
    51541 attgatacca aggcttttta aaagtctaaa acccgactta ctacgttttc cgctacgttt
    51601 gtgttaaaca gcgacaagtt cagccaattt gtcagcaaca tcatcctttg attttttgga
    51661 caagtgagta tataaatcca ttgtgattgc tattttagcg tgacctaacc tctcttgtgc
    51721 aatcttagcg ggaatcccag cctcaaacag taacgaagcg tgggtgtgtc taaacccgtg
    51781 gggagtaatc ctttttaatc catgcttcaa tataagttta tccagtctgt ttctcacagt
    51841 gtcgcaagaa aaattaaaca atttaaacga tccgtgtaaa ggtttgatac tttgcttaat
    51901 atataatttg gctaacgaca tggtctcagc gtccattgat atagcgcgag tgcttttttt
    51961 ggttttagga gattgtacag cccatccttc ttttgtatag gcaatagttt ttgtaatgct
    52021 gatagtattg ttatggaatt caaagtcggt atcttttaaa gccattaatt caccaattct
    52081 aaaaccgcca taactcagca atctataaat cagacgcatc tctagacttt cttcagcttc
    52141 cacaatcctc aagaaagtat tcaattcctc ttttgtgtaa tattttttgg tgagtgtatt
    52201 cacgtttttg taagtgcact ttgatctcaa tgtcttgctc atagggttat tatcaataat
    52261 acctaaattg acagcaaatt taaaaattct gtttgctaga cttagataaa gcgtataacc
    52321 gctatatcga gacaagcaat tcacaaattt ttgacaaatc atgacagtta tcttcgtcat
    52381 ttgcagttgt cctaaatgtg gctttaaaat tgttttatag tagttttggt taaccagaaa
    52441 tgttgacggt ttgactgtat tcttatactg ttcaaaccac agtttagcta cgtcatcaaa
    52501 tgtagttcta tcattgcttt tccaggcgcc ttgacgctga aaatcatcaa taagttttac
    52561 ctcggctctt ttagcttctc tttccgtttt aaaaccttgc ctagttgtcc tgacttgttt
    52621 accagtcacg ggatcaaccc cgaggtatgc tcttaagcaa taggcagttg tgccatcttt
    52681 tttagtgtat tttttaatca ttgtttttcc tctctctttg cgctggggag tgctgatttt
    52741 gagataggat attggcatca cctcctaaaa atggtataat taggtacaag aaaacgagcc
    52801 atttaatgct tgtttcttat tgattgcata tcgcctcacg ctctcctcgc caaatttgag
    52861 cgtggggctt ttttatttgt ctttattatt gtcttctagg tgtttaatag cataatttac
    52921 ttctttttta gtaaaaccac caccgtcgct gttagcagaa agttgttctt ttatcgtttc
    52981 ttttgatgcg ccgaattttt gcatactttt agcttgggca agtgcattct ttttccagtt
    53041 tatctttaat tttttcgctg cataatcaac agctttcttt tcaaatttac tttcgttaat
    53101 catcatgtca taaaatgctt tttttgacat attggcgtct ttcaccattt ttgctgtttc
    53161 taaagcgttt tggtattcct ttgatacagc aactacagta acagattgac taaataactt
    53221 gttagataat tctggagttg tagctgtagc cataactcca acaacaacta tcgcaataat
    53281 tgaacatttt ttcataataa atctccttat aaaaataatc ttaattttta aaatttaccc
    53341 aaaaacttct tcgttggacg ggattgtcat tttcccgaat aactccccac aacctcacca
    53401 ataattctaa agtcgctatc tgcgtcaatc ggaatgtcat cgtacttgct atttaaactg
    53461 tgcagaaatg ccccctcggc gtttataagc aactgtttga tataagcgtc accatagtat
    53521 tcaaagacgc ctatatcgcc atccgtgagg tctacggata gcttaacaaa tacataatcc
    53581 ccagagtgat acttcggttc catggaatca ccataaacag ggataacaaa gtctgcgtca
    53641 taatcgactg gtaactcaat tttttctact tgtacatcat ttagatactg acctgtacca
    53701 gctgaagctg cgtggtcgta gtagttgtaa gaaaataatt ctactactgt attcttacta
    53761 tcttctactg tgttttgttc agataaaaga ttttcaccgt aacttatcca atcactgtga
    53821 cgaggttctt tgagttcttt gtctaattgg atgacgatgt tagaagtagc agaaataatt
    53881 tcaggagaat acatttctac taaatcagat ttttcaacgt taaaatagtt agccatcaat
    53941 tcgattttgt cgattcttgg ataagttttg gcgtttaccc aatctaaaac tgtgctgtac
    54001 ttaaaattca tcgcttttga aaactcttta gggttcatat tctttttttc taaatgcctt
    54061 cttatatttg aagccattat ctttttattt ccgagagacc cactcataat aacacctcat
    54121 ttctagttgt attataacgg ataaaccgtg cttttgtcaa aaaataattt aaaaaataaa
    54181 aaaaatagca gttttgtgtt gacaacacgg tttaaccgtg ttaaactata atcaagctta
    54241 aggaattaag caaaacgaaa ggaggtacag ctgatgaagt ctaggctaaa caaaaagcct
    54301 aaacacaaag aactagaagt cgaaatcaag attctttggt ttaagcttag aattaaatat
    54361 ctgattacta ggtaatcgga tagggggtga aataccccca ccccatttag gggtaagttt
    54421 agtttagcac attggctgta tctccgcaag aatgaaagga gaggttatga gagaacgaaa
    54481 tgaaaagttc atcggagtgc taaaagatat gcacatgcaa attttgcgag acttcacaaa
    54541 cgaagaagac cccttaacaa ggtgcgagct tgctaaaggg ttcctcgaaa ttggtgacta
    54601 tttatccaaa caatgactcg ccacgctcaa gagcttcggc tataacttta ccattattga
    54661 tttgttcttg cttttcggct tcaacgaaag gtaaattatg ttgcttaata gcttccacag
    54721 agtcttcgta aagtttgatt ttatcttcga tagacaaagt agggctagaa gaagcgacaa
    54781 tagcgagagc taaatctttt gaattagaaa ttttcattag cttatcctcc tttctgctag
    54841 gataagttga ttataacatt tttaggaggt acaaaatgag ttggaaaaaa ctaatgcttg
    54901 gcgacttaga acacacgttt actagtcgtg atggcaagga aaaaacaagc gttgaatttg
    54961 aaggcggtgt attaccagct ctgttagtgc taggtggtat cacttggctg attgcttggt
    55021 ttattacaaa ataaaaactc cccaaaagga gtggaaagga gggaaggcat ggaaaaaatt
    55081 aaatacggtg tactaggttc ttccaagata tttcacacaa gaaaatctgc tctcactcat
    55141 gcaaatcttt taggatatcc tcgtagtgcg gtttttttga taattccaca gggaatgacg
    55201 cagaaaatga ttgataaggt gaattaacat atcctgcttt attagcttta aatagttttt
    55261 tctttttagc tactttaaaa gcaacaaaga gtctatctgt gatttcagac gtttgtatga
    55321 ttaaatccat ccttgtcata ctgtgggctt ttaatactcc acaatctgcc tctggaacct
    55381 cgataaggat tgtattgcca tcaggctgta ctgcggctat agcctctcta cctgttaaat
    55441 cgttaattat attattttgc ttttggtaat aatgctgata ttttctgttt ttatcaaaaa
    55501 caatcaagtc gaagtagctt acatcaacat tagaaggatt gatgatttta atgttagctc
    55561 ttaatgtacc atttggatta tatatgcttt caccgttgtc taaaataacg ctcaaaatcc
    55621 aatctgaaac aggagcagca attaactcga cttgtaagtt atttcttcgg tagtttgaat
    55681 aagatagaaa cagagctatt aaagctatcc aattttttat tagatattca cttgtaaact
    55741 taaaaacaca caataaaaaa ttaaaaaaat tcatttcaac ctcgcaattt ttatttaaat
    55801 tataccacag aaaattttaa agctatgttg ttttggataa ttccaaatta gaaagggggt
    55861 gggggaatga cgaaaatgac attgaaaatg cttagggttt cgaagaattg gaaccaagaa
    55921 acagcagcta aaaaactaaa aatttcagtt tcgaaattaa gcaattggga aaatgcaaaa
    55981 acatttccag atgctattga aataaataaa attgaaaaac tatacgatgt caattactct
    56041 gatattattt ttttaccaac aaaacacggt ttaaccgtgt aaaatgatag acaactcacc
    56101 actagaaagg ataaaagaaa aaatgctact aacagcagca cttattttga ttttactaac
    56161 gaatatcgct atcttaacta ttattgtcaa aatggggaaa gaataactga tttatagaaa
    56221 ggacacacaa tggaaattaa agatatgaaa gtaagtgtcg atgtaaggat taaactaagt
    56281 aattccgaag cattcagaga gatggtacgt gaattcaaca caaaggctca cgaactaagt
    56341 ttaatagccc atgaacttga gatgtttgtg tttgaaggtg aaatcgaaaa tcgagtttta
    56401 tcagatgatt gcaatgaaca atcagatctt gcctgaaata tagaaaggga ccacatgaga
    56461 ccaaagcgat atccgtatca aaaaaataaa ttaattatcc agtcgaaaaa cgcaaagaca
    56521 aaaattgaat tagatagcgg aaaaataact atcaatgctg aagaaatcaa ggttggtgat
    56581 ttagcaaacg aaatttcaaa agtgcaacta gctaataaag aaatagctga aactatcggt
    56641 caagataaaa agtctactga aacagtagac tctaggattt cacaacttga aaaagaggtc
    56701 gaaggattga aaggagttgt tggaacagca tatcgacttg ctacagagac ttatcatcga
    56761 atttccaaac aatcttctac ctcagtaact gagtagccgt tgttctgaag ttcctggatt
    56821 atttcgtctt taggaatttt aaactcctta ggatatatat aagcaacata gtctgttctg
    56881 attggatctt caaatacata ttttaaaaca gtatcgatag tatcccaatc tttgtaaact
    56941 ttttgaattt cattctttgg agttaattta ctcataacct tccctccttt ccataatttt
    57001 tgaatataac ggtgagaggt catattcaaa taaattatat cagaaaggaa cgaaagacac
    57061 aacatatagt tatgaataca aaaacaaaac acaatatgtt gatttttcaa tgtagattat
    57121 gtgggaaaaa attgaacaat tgatgattga gagaaatctc aatatgaaca aattagcaaa
    57181 attgacaggg attcacaaaa gccactttag cgatttgaaa agtggaagaa ttaaacatct
    57241 gtcatggccg aacatggtca agctatctac aggattaaaa gtcagcttgg acgaatttaa
    57301 ataacaaaaa agtccgacgg gaatcggact ctaaacaaac tttaatttac ttaattatac
    57361 cacgaaagag gtgataaatc catgcaatcg caacttactt acgatctact caaaaagcag
    57421 atagcagaag aactttttga tgagtttaag gagctcatac aagaaaaaga tttagcgaat
    57481 cggtgggtca accaaacagc actcgtcaat gaatacggct actcatggca aactataaaa
    57541 cgcatggaga gctatggcct taaatctttt aaaaacggta aagacaaaat gtactgtctt
    57601 gctgatgtta acgaaattaa acacttaatg aaacaataag cgctggggag tgctagagga
    57661 gaaacaacat gaaactatta gattttattt tcgcaaaacc aaaaaaacag gaagaaaaac
    57721 caaaatggac aattgaaaac aacggttggg aagctaatgc acgtagatat aaccaaaagc
    57781 acggtttacc tgctaaacaa atttggtagg aaacacatag tcctttgaca actgaatatg
    57841 ggtgcgttga gaaatattta aaaaagtttg atttaggggt tgacttatgt atccacataa
    57901 tgatattata tatttgtgga tacgaaagga ggaaatatga ccactaccaa aaaacttggt
    57961 cgtccaactt ctaatcctaa gtctcatagc aaaagactga gaatgacaga cgaagaagta
    58021 caaaaattag aatattgtac taaacaaact ggaaaaactc agacagatgt tttgatgcta
    58081 ggcttagata aggtctatca agagctaaaa aaatagcgta taatccgcca tcgccaaact
    58141 ttggattaca cgctatcgac cgacctgaaa acaggtacac aaatatatta tcatgtgtac
    58201 ccttttcagt caacctgaca agggtatttt ttgcgccctt gttgtttaga taagggtttt
    58261 tattgtaccc aaaaatagga ggaacacaat ggataattca aaactagaaa atcatcaaaa
    58321 agtaacggta gtctgtacag attttaatgt ctatttgaat ggaatacgac ttactggagc
    58381 tagaccagaa accgctaaat tagctgagag atgcggagag aaactcatta cactaagtct
    58441 agtagttaca gattttgatg accatagaac acctaagatg gcggatatgg caaaggaggc
    58501 tgagatggct aataaaacat tggactggga gaaaaagcat ttctataaat ctaataaata
    58561 atgtatctca gagcgttata gattgattct ggattttgcg aaactccaaa ttcattaagc
    58621 cattcgataa cctcggtttc tacctgcccg atatatccaa gaaaatacat gccttttggt
    58681 gtcagaccgt caattgtata tattcgtcta tctaatctcg gcatttctgt ggcagtaact
    58741 aaatcttgtt ggatcaaaca atctagggtg taaaaaataa tttcttcaac ttctcgataa
    58801 gggtattgag aatatatcct ttttccttct tctgttgcaa taaggtattg aagtaaatct
    58861 acacccgtat ccaacttatg atatccgatg gcttcaagtg aatttttgta taaagaatag
    58921 taatcaatca tacacttctc caagtatttt attttaaata taacaaaata gtaagaggaa
    58981 aacaatatgg ctaaaattta cacactaact gaagaagaat tgaatgaatt agtagctgaa
    59041 cgcatgaaac aagcgaaaga aaaacgcaca ccgcaagggc tattcaaaga tgtcagcttt
    59101 gatgatgaat tgattccaat caatgaaaaa tatccaaaag tactcaagaa attaaatcgt
    59161 gaacgtgctt ataaaccaga aaaacacgtc ttcaatcaga caccaaaagt ttttggtgtg
    59221 gacaacgata ttagttatag caaaattaca acacatgacg tacacaacca tattcgtttg
    59281 cttgtcctaa atgtctttgg taaaagtcaa aataaggaag tattgcccga ggaatacgac
    59341 caagcaatag aactttacaa tcaattaaaa gagtggtttg tgtctagcta tgataagcga
    59401 ttagagggat tggtgctaga agatgattaa aaaattctgc gttaactact tactaaaaca
    59461 gattgacaaa agcaaactag aaacaagaga taaagcgaag ttgaaccact ttatcacact
    59521 agtggactac aagttgggag gataaatggc acagaaatca aaaacaaaaa tctattattg
    59581 gctgaaattt gataagcatt tttttgacaa tttatttatt aaaaggcttt taagaaattt
    59641 ccctggcggt tcggaaatga ttgttattta catcaggctc atgttagaag ctattgagaa
    59701 tgattgcatc attgattacg aaggaacttt tgataattac gcagaagaac tagctcttcg
    59761 tcttgaaact tcagaagaac agataaatat ggctttagca tattttgtga aatgtggagt
    59821 cattcaggtt gatgatggtg gtaacaccca ttatccgcaa gcaaaggcct tgttggggca
    59881 ggaaacaaac tggaatagat acaagaaaaa acaagcagaa ttggaaaaat tccaactact
    59941 ttccaaccaa gttccaacag agatagagaa agataaaaag atagatataa atatagatat
    60001 aaagtcagaa gtagaagaag agataaaaga ttcatcttct gctgctaatg taaataactt
    60061 aaaaattata tctgattatt ttcaacaaga aattggcatc ttatctccga atcagtttga
    60121 gcagttgtca gactatatca ccatcacaaa aatggaagtg gatgttgtta aggaagcgat
    60181 aacgagagct gctgacaatt ctaaacgttc ttttggatac gttaactcta tattgcgaaa
    60241 ttggagacaa aacggaatcc ttacgatggt taaagttgaa gaagaacaaa ggcaattcca
    60301 atatagaaaa tctaaacaag aagaggtatc ggaatatgat acttggtgac gaagacgcac
    60361 ttactaaaat cgctatatct tatcaacaaa acaccaagaa acaagatgct gtctgtgaaa
    60421 aacacggttg taggtacatc acagtcctta agactggttt gacagtatgt ccagattgtc
    60481 acagagaaga attagacaat caaaacactt tgcacgtcca aaagcaatat gagagagaac
    60541 ttgaaaacaa gcgactgtac tatctcaaaa aattatcaat tatggacgac gagttggaaa
    60601 atgcatcatt tgacaatttt agggctgata cggctaaaca caaagaggtg ctttattggg
    60661 caaagacaat ggctaacgat tggtttagtg gtggtaaggg aaacatcatc atgactggca
    60721 aagcaggacg aggcaaaagt catttagctt atagcatcat taggggattg tctgataaaa
    60781 cgaaaaaatt aggcttgctt gtaaatgtca ctgacttact gtcagagata aagcgagact
    60841 ttagcaagga agcattttgg atggataagc taaaagatgt cgattatctg gtgctagatg
    60901 atctaggtgc cgaaaaagtt agtgactggt ccacaagcat tatttacagc ttgcttaaca
    60961 agcgcacaaa cacaatcatt actaccaatc tgacacctgc cgaaattaga aaaatttatg
    61021 gagagagaat tgcatcccgt atcagaaaag gctgcgacaa aagtcatatc atggaatttg
    61081 atggcatgga ggacgaaagg atgaagctat ggaattgaca ctaacaacat ttttcgggct
    61141 atccgaggaa catgcggcaa aaatcatggc gctagatgaa gatgtccgaa caaagaaaat
    61201 tgaagaattg agagcatgga gagagtgctc aaaagtcacg ttttaggaga gatttaatat
    61261 ggtaatgcca ctagatgagt tagaaaaaag aatattttgt tatttgccga taggaagtaa
    61321 tatgatggtt aattcaaagg aaatttgtcg aacatttgac atcaaagacc cgaaaacctt
    61381 gagagacatt atccacggaa tggtaatgaa aggctatttg ataggttcta gccgtcgaaa
    61441 aggcggaggg tactatctaa ttgacaacga tgatgagcgt gcagaagcta tcagctcact
    61501 tgaaagtcaa gttagaaaag aacaaaagcg gataaacatt ttaaaaaacg gaaacttgaa
//
LOCUS       DAXMQE010000009        54351 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.009, whole genome shotgun sequence.
ACCESSION   DAXMQE010000009 DAXMQE010000000
VERSION     DAXMQE010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 54351)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54351)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54351
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.009"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            <1..724
                     /locus_tag="ACF4ZO_000612"
     CDS             <1..724
                     /locus_tag="ACF4ZO_000612"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HFD5486183.1"
                     /translation="TTIENAAREPEIVDLAQFLNKMGARIRGAGTETLTITGVTHLRG
                     VEHDVVQDRIEAGTFMVAAAMTSGNVLIRDAVWEHNRPLISKLMEMGVSVTEEEYGIR
                     VQANTPKLKPVTVKTLPHPGFPTDMQAQFTALMAVVNGESTMVETVFENRFQHLEEMR
                     RMGLQSEILRETAMIHGGRQLQGAPVMSTDLRASAALILTGIVAQGVTIVNNLVHLDR
                     GYYQFHEKLAKLGATISRSSEV"
     gene            728..916
                     /locus_tag="ACF4ZO_000613"
     CDS             728..916
                     /locus_tag="ACF4ZO_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HFD5486184.1"
                     /translation="MTNGLKYVLEQMLLLLVIAALACLFLAIGLMIGYSFMGDGQSPW
                     HILSMDKWAELVNKFTGK"
     gene            952..1818
                     /locus_tag="ACF4ZO_000614"
     CDS             952..1818
                     /locus_tag="ACF4ZO_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HFD5486185.1"
                     /translation="MLAKKKRKRVLNSFLLILLVLGSNCLAKSDFIASNHPIKQLYQT
                     LVGEKKKSLLTHNNLPADVPTEALAASVLTPSIKKQLGPDVQWNGAGAYIINRNKTDL
                     NAKVASLPYANNETKWVQEQKVPKRANALLTKSTRQYRNRYQTDNAYRNFKPAGWHRL
                     HRLKGSYDHAVDRGHLLGYALVGGLKGLDASTGNPDNIATQLSWANQANKPYSTGQNY
                     YEGLVCRALDKGHRVRYRVTLLYDGDNLLASGSHLEAKSSDDSLTFNVFVPNVQPGLT
                     VDYRTRQIAINL"
     gene            2101..3144
                     /gene="pheS"
                     /locus_tag="ACF4ZO_000615"
     CDS             2101..3144
                     /gene="pheS"
                     /locus_tag="ACF4ZO_000615"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019314825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HFD5486186.1"
                     /translation="MDLQAQLEELKTKTLETLQSLTGNHTKELQDLRVAVLGKKGSLT
                     ELLKGLKDLSNDLRPVVGKQVNEVRDLLTKAFEEQAKIVEAAKIQAQLDAESIDVTLP
                     GRQMTLGHRHVLTQTSEEIEDIFLGMGFQIVDGFEVEKDYYNFERMNLPKDHPARDMQ
                     DTFYITEEILLRTHTSPVQARTLDQHDFSKGPLKMVSPGRVFRRDTDDATHSHQFHQI
                     EGLVVGKNISMGDLKGTLEMIIKKMFGEERSIRLRPSYFPFTEPSVEVDVSCFKCGGK
                     GCNVCKKTGWIEILGAGMVHPSVLEMSGVDAKEYSGFAFGLGQERIAMLRYGINDIRG
                     FYQGDQRFSEQFN"
     gene            3354..5759
                     /gene="pheT"
                     /locus_tag="ACF4ZO_000616"
     CDS             3354..5759
                     /gene="pheT"
                     /locus_tag="ACF4ZO_000616"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HFD5486187.1"
                     /translation="MLVSYKWLKELVDIDVTPAALAEKMSTTGIEVEGIEVPAEGLSK
                     LVVGHVLSCEDVPETHLHLCQVDTGDETPRQIVCGAPNVKAGIKVIVAVPGARIADNY
                     KIKKGKIRGMESLGMICSLQELGLSDSIIPKEFSDGIQILPEEAVPGDAIFKYLDLDD
                     HIIELSITPNRADALSMRGVAHEVAAIYGKSVSFPQKNLQESDKATSEAIEVAIASDK
                     VLTYASRVVENVKVKPSPQWLQNLLMNAGIRPINNVVDVTNYVLLYFGQPMHAFDYDK
                     FEDHKIVARAARQGESLVTLDGEKRDLTTEDLVITVADKPVALAGVMGGQATEIDGNS
                     QTVVLEAAVFDGKSIRKTSGRLNLRSESSSRFEKGVNYATVLEALDFAAAMLQELAEG
                     QVLSGHVQAGQLPTEPVEVSTSLDYVNVRLGTELTFADIQRIFNQLGFGLTGDETRFT
                     VAVPRRRWDISIPADLVEEIARIYGYDKLPTTLPEAGGTAAELTPTQALRRKVRGLAE
                     GLGLTEIISYALTTPEKAIEFAVAPSHLTELMWPMSVERSALRQNMVSGMLDTVAYNV
                     ARKQSNLALYEIGKIFEQEVNPKEDLPNEVNHFAFAICGLVAQKDFQTQAQAVDFYHA
                     KGILDTLFANLNLKVQYVPTKDLANMHPGRTALILLDEQVIGFVGQVHPGTAKAYSIP
                     ETYVAELDMAALEAALPSDQTFVEITKFPAMTRDVALLLDREVSHQTIVTAIESAGVK
                     RLTKIKLFDVYEGATIQAGQKSMAYSLTFQNPNDNLTDEEVAKYMEKITKSLTEQVGA
                     EVR"
     gene            5871..6248
                     /locus_tag="ACF4ZO_000617"
     CDS             5871..6248
                     /locus_tag="ACF4ZO_000617"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004601 - peroxidase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="OsmC family protein"
                     /protein_id="HFD5486188.1"
                     /translation="MYQTKITGNRLYHTVSKGYGDSVTLFGKTDQGETPMSLLVIALS
                     SCVTMCVQGFYHRQFQQDTLAVSAEASYEEEVFELLVRIDDVLDDKKKADLLAYIGAY
                     CRVKQLLKPEVTVTITLEGLSHV"
     gene            6241..6627
                     /locus_tag="ACF4ZO_000618"
     CDS             6241..6627
                     /locus_tag="ACF4ZO_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbgA family protein"
                     /protein_id="HFD5486189.1"
                     /translation="MSDASLKTYQKQWAYQKYWVMAHSQQHYNALRELFKGNQWSEEK
                     VLTFHCLIEEAQAIPPTVKSLRTAYQHVWGYFKKVASQEEKDHFKDLDAQLETKSEEM
                     LCFLQEMTAHYQPSYLLSCRLITKGP"
     gene            6700..7776
                     /locus_tag="ACF4ZO_000619"
     CDS             6700..7776
                     /locus_tag="ACF4ZO_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD5486190.1"
                     /translation="MFLALNEMKQSKLRYGLIAGLLCLVAYLMFFLSGLAFGLMQENR
                     SAVDLWKADSVLLAKDADATLTLSQVSRAQENQITADKVAPLAQLNTVAWSVKNPKDA
                     DKVKVSLFGIDSNSFIRPNIVKGRLFKTNKEVVLDQSLAKEEAFAIGKDFYTSSSSQA
                     LTIVGYTQNARFSVAPVVYMNLEAFETLKYGEPLPKDKQVVNAFITKGSLIDYPKKDF
                     QKLDIKTFITKLPGYSAQLLTFGFMISFLVIISAIIIGIFMYILTIQKAPIFGIMKAQ
                     GISNKTITTAVLMQTFFLSFLGSGLGLLGTWLTSLLLPTVVPFQSNWFLYLAIFVSMI
                     CFALLGTLFSVFNIIRIDPLKAIG"
     gene            7786..8454
                     /locus_tag="ACF4ZO_000620"
     CDS             7786..8454
                     /locus_tag="ACF4ZO_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD5486191.1"
                     /translation="MSVLTFKQVIKTFQDGHHEINALKATDFSIEAGEFVAIIGPSGS
                     GKSTFLTIAGGLQTPSSGQLIIDGTDYTHLSEKERSRLRFKSVGFILQASNLIPFLTV
                     QQQLELVDHLTGSKEKAKANQLFDDLGITGLKHQLPQELSGGERQRAAIARALYHDPA
                     LILADEPTASLDTEKAYEVVKLLAKESKEKNKAIIMVTHDDRMLEYCDKVYRMQDGEL
                     RQER"
     gene            complement(8559..9476)
                     /locus_tag="ACF4ZO_000621"
     CDS             complement(8559..9476)
                     /locus_tag="ACF4ZO_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="neutral zinc metallopeptidase"
                     /protein_id="HFD5486192.1"
                     /translation="MKTDDLRESQQVEDRRGQSSGSFGGGGLGGGLLLQLLFSRGGWK
                     TKLVILLLLLVMGGGGLSGVLGGKPSSTNNNAYQSSQVTRTNGDKASQEQVSFVSKVF
                     ASTEDYWTKTFREKGLTYHKPTLVLYTGATQTACGRGQASSGPFYCPGDQKVYLDISF
                     YNELSTKYGAKGDFAMAYVIAHEVGHHIQNELGIMDNYASARQGKSKAKANQLNVKLE
                     LQADYYAGAWANYVQGQGLLEKGDIEEAMAAAHAVGDDTLQEETYGRTVPDSFTHGTS
                     KQRQRWFDRGYQYGDFEHGDTFSIPYSKL"
     gene            9627..12842
                     /gene="rexB"
                     /locus_tag="ACF4ZO_000622"
     CDS             9627..12842
                     /gene="rexB"
                     /locus_tag="ACF4ZO_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0000724 - double-strand break repair via
                     homologous recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HFD5486193.1"
                     /translation="MKLIYTEMSYSMTEILVNEARKAADQGYRVFYIAPNSLSFEKER
                     EVLTLLPERGTFSIIVTRFVQMSRYFTVESSPSKQHLDDTTLAMIFYRALMQLKPEDL
                     PSYGRLQNNSVFIEQLVELYKELKNAQLSVHDLTGLDHPQKQEDLIKIIELAETIMIQ
                     QDYNQDSPLQSFARAIKLGLLNNQLSKTVVVIDGFSRFSAEEDYLLSLLNNNCQEVIT
                     GSYVSQKAYQKSFIKGNIYEASLHFLQDLAQKYHIKPVFATSNQVFKPAFSRLTQLFE
                     ATHDFSQVDWQFQKNDLDHFSLWQCHHQKEEIEHVAKSIRQKLYEGYRYKDILVLLGD
                     MDAYQLQIGPIFDKFEIPYYLGKAEPMAAHPLVQFIESLERSQRYNWRREDILNMLKS
                     GLFGCFDDSDIDRFEEYTQFADIKGFTKFSKPFTINSSRQYPLDFLNEMRQDIVLPLQ
                     ELFKSQKQLGASLVDKLILFLKKIRLAENMQGLAQSQLEVEKNEEVWKRFTDILTSFH
                     HIFGQEKLRLSDCLALIKTGMKSAQYRVVPATLDVVTIKSYDLVQPHSKPFVYAIGLT
                     QSHFPKQIHHSGLLSDQERARINEIRNYRHFDIASAENSKKNHQTALSLFNAATKELV
                     LSVPTVINETFDDLSPYLKELINFGLPLLDKGKNYLSYDNSDIGNYKALLSQIIAINR
                     QDLIEMSDQDKMFWTVVLRYLRKQLRKQQLELPTSDYRLSTKSLSKEVIEVCFPKGIP
                     LKLSATALTVFYNNQYNYFLKYVLNLNKTESIHPDSRIHGQYLHRVFERLMKDHTQEP
                     FDNKLKQAIYHTNQESFFQQVYQDNAEAEYSLAILEDIVRSTAPILQLNQNIKVIDQE
                     KNFHLDMGNEILVHGIIDRIDQLSDGSLGVVDYKSSANQFDIGTFYNGLSPQLVTYLA
                     ALKQIAPHDINQLFGAMYLHLQDPKLDLVTFKQIDNTLVESIYKALTYKGIFSEVEKE
                     HLSTGAYQTKNALYSNDELETLLNYNKYLYLKAVKHIKKGHFLINPYTSDGKTVQGDQ
                     LKAITRFEADLDMAQARRLVTLPAKEKKECFLTLMRKESHL"
     gene            12839..16471
                     /gene="addA"
                     /locus_tag="ACF4ZO_000623"
     CDS             12839..16471
                     /gene="addA"
                     /locus_tag="ACF4ZO_000623"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA];
                     GO_process: GO:0000724 - double-strand break repair via
                     homologous recombination [Evidence IEA];
                     GO_process: GO:0006302 - double-strand break repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HFD5486194.1"
                     /translation="MISFAPFLSPEAIKYLQENERCSDQSQKRTAQQIEAIYTSGQNI
                     LVSASAGSGKTFVMVERILDKILRGVSIDRLFISTFTVKAATELRERIENKLYSQIAQ
                     TTDFQMKVYLTEQLQSLCQADIGTMDAFAQKVVSRYGYSIGISSQFRIMQDKAEQDVL
                     KQEVFSKLFSEFMNQKEAPVFRALVKNFSGNCKDTSAFRELVYTCYSFSQSTENPKIW
                     LQENFLSAAKTYQRLEDIPDHDIELLLLAMQDTANQLRDVTDMEDYGQLTKAGSRSAK
                     YTKHLTIIEKLSDWVRDFKCLYGKAGLDRLIRDVTGLIPSGNDVTVSKVKYPVFKTLH
                     QKLKQFRHLETILMYQKDCFPLLEQLQDFVLAFSEAYLAVKIQESAFEFSDIAHFAIK
                     ILEENTDIRQSYQQHYHEVMVDEYQDNNHMQERLLTLLSNGHNRFMVGDIKQSIYRFR
                     QADPQIFNQKFRDYQKKPEQGKVILLKENFRSQSEVLNVSNAVFSHLMDESVGDVLYD
                     EQHQLIAGSHAQTVPYLDRRAQLLLYNSDKDDGNAPSDSEGISFSEVTIVAKEIIKLH
                     NDKGVPFEDITLLVSSRTRNDIISHTFNQYGIPIVTDGGQQNYLKSVEVMVMLDTLRT
                     INNPRNDYALVALLRSPMFAFDEDDLARIALQKDNELDKDCLYDKIQRAVIGRGAHPE
                     LIHDTLLGKLNVFLKTLKSWRRYAKLGSLYDLIWKIFNDRFYFDFVASQAKAEQAQAN
                     LYALALRANQFEKSGYKGLYRFIKMIDKVLETQNDLADVEVAAPKQAVNLMTIHKSKG
                     LQFPYVFILNCDKRFSMTDIHKSFILNRQHGIGIKYLADIKGLLGETTLNSVKVSMET
                     LPYQLNKQELRLATLSEQMRLLYVAMTRAEKKVYFIGKASKSKSQEITDPKKLGKLLP
                     LALREQLLTFQDWLLAIADIFSTEDLYFDVRFIEDSDLTQESVGRLQTPQLLNPDDLK
                     DNRQSETIARALDMLEAVSQLNANYEAAIHLPTVRTPSQLKATYEPLLEPIGVDIIEK
                     SSRSLSDFTLPHFSKKAKVEASHIGSALHQLMQVLPLSKPINQQTLLDALRGIDSNEE
                     VKTALDLKKIESFFCDTSLGQFFQTYQKHLYREAPFAILKLDPISQEEYVLRGIIDAY
                     FLFDDHIVLVDYKTDKYKQPIELKKRYQQQLELYAEALTQTYKLPVTKRYLVLMGGGK
                     PEIVEV"
     gene            16611..17423
                     /locus_tag="ACF4ZO_000624"
     CDS             16611..17423
                     /locus_tag="ACF4ZO_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HFD5486195.1"
                     /translation="MNFKKIRFGFLLCLLLYPLAACNKSEQLNHYERIKKTRKLVVAV
                     SPDYAPFEFKALVNGKDTIVGADVQLAQAIADELDVDLELSPMSFDNVLSSLQTGKAD
                     LAISGISHTKERAKVYDFSIPYYQAENAIVMRASDAKVTKNISDLSGKKVAAQKGSIE
                     EGLVKIQLPKANLISLTAMGEAINELKAGQVYAVTLETPVAAGFLAQHKDLALAPFSL
                     KTSDGDAKAVALPKNSGDLTKAVNKVIAKLDEQERYKSFIAETIALTKNTMK"
     gene            17564..17740
                     /gene="rpsU"
                     /locus_tag="ACF4ZO_000625"
     CDS             17564..17740
                     /gene="rpsU"
                     /locus_tag="ACF4ZO_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HFD5486196.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVTKAGTLQESRKREFYEKPSVK
                     RKRKSEAARKRKKF"
     gene            complement(17867..18229)
                     /gene="mscL"
                     /locus_tag="ACF4ZO_000626"
     CDS             complement(17867..18229)
                     /gene="mscL"
                     /locus_tag="ACF4ZO_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HFD5486197.1"
                     /translation="MVKELKAFLFRGNIIELAVAVIIGGAFGAIVTSFVNDIITPLIL
                     NPALKAANVENITQLSWNGVKYGSFLGAVINFLIIGTSLFFVVKAAEKAMPKKEKEAA
                     APTQEELLTEIRDLLAQK"
     gene            18359..20173
                     /gene="dnaG"
                     /locus_tag="ACF4ZO_000627"
     CDS             18359..20173
                     /gene="dnaG"
                     /locus_tag="ACF4ZO_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003896 - DNA primase activity [Evidence
                     IEA];
                     GO_process: GO:0006269 - DNA replication, synthesis of
                     primer [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HFD5486198.1"
                     /translation="MGFLWGGDDLAIDKEMISQVKNSVNIVDVIGEVVKLSRSGRHYL
                     GLCPFHKEKTPSFNVVEDRQFFHCFGCGKSGDVFKFIEEYRQVPFLESVQIIADKTGM
                     SLNISPSQAVIASQHKHPNHALMTLHEDAAKFYHAVLMTTTIGQEARKYLYQRGLDDQ
                     LIEHFNIGLAPDESDYLYQALSKKYEEGQLVASGLFNLSDQSNTIYDAFRNRIMFPLS
                     DDRGHIIAFSGRIWTAADTEKRQAKYKNSRGTVLFNKSYELYHLDKARPVIAKTHEVF
                     LMEGFMDVIAAYRSGYENAVASMGTALTQEHVNHLKQVTKKVVLIYDGDDAGQHAIAK
                     SLELLKDFVVEIVRIPNKMDPDEFVQRHSPEAFADLLKQSRISNVEFFIDYLKPTNVD
                     NLQSQIVYVEKMAPLIAQSPSITAQHSYINKIADLLPNFDYFQVEQSVNALRIQDRQK
                     RQGQIAQAVSNLVTLPMPKSLTAIAKTESHLMHRLLHHDYLLNEFRHRDDFYFDTSTL
                     ELLYQRLKQQGHITSYDLSEMSEEVNRAYYNVLEENLPKEVALGEIDDILSKRAKLLA
                     ERDLHKQGKKVRESSNKGDHQAALEVLEHFIAQKRKME"
     gene            20182..21291
                     /gene="rpoD"
                     /locus_tag="ACF4ZO_000628"
     CDS             20182..21291
                     /gene="rpoD"
                     /locus_tag="ACF4ZO_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HFD5486199.1"
                     /translation="MTKQKEITTFNVQVAEFIRHHKKEGTAIDDDVTEKLVIPFALDA
                     DQIDDLLERLTDGGISITDKEGNPSSKYIVEEPKPEELTDEELIGSNSAKVNDPVRMY
                     LKEIGVVPLLTSEEEKELAVAVAKGDLMAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMEMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRVVLREQLDEVLDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRHPSRSKQLRDFIED"
     gene            21528..21866
                     /locus_tag="ACF4ZO_000629"
     CDS             21528..21866
                     /locus_tag="ACF4ZO_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HFD5486200.1"
                     /translation="MSDTPKYTQDQVIAIKNRILEALETVIDPELGIDVVNLGLIYEI
                     RFNDNGYTEIDMTLTTMGCPLADLLTDYIHDALQDVPEVTKTEVKLVWYPAWTVDKMS
                     RYARIALGIR"
     gene            22004..22858
                     /gene="rfbD"
                     /locus_tag="ACF4ZO_000630"
     CDS             22004..22858
                     /gene="rfbD"
                     /locus_tag="ACF4ZO_000630"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008831 - dTDP-4-dehydrorhamnose reductase
                     activity [Evidence IEA];
                     GO_process: GO:0009243 - O antigen biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HFD5486201.1"
                     /translation="MILITGSNGQLGTELRYLLDERGVDYVAVDVAEMDITNEDKVEA
                     VFAQVKPTLVYHCAAYTAVDAAEDEGKALNEAINVTGSENIAKACGKYGATLVYISTD
                     YVFDGNKPVGQEWVETDRPDPKTEYGRTKRLGELAVERYAEHFYIIRTAWVFGNYGKN
                     FVFTMEQLAENHSRLTVVNDQHGRPTWTRTLAEFMCYLTENQKAFGYYHLSNDAKEDT
                     TWYDFAKEILKDKAVEVVPVDSSAFPAKAKRPLNSTMNLDKAKATGFVIPTWQEALKA
                     FYQQGLKK"
     gene            22977..24131
                     /gene="cps2T"
                     /locus_tag="ACF4ZO_000631"
                     /gene_synonym="wchF"
     CDS             22977..24131
                     /gene="cps2T"
                     /locus_tag="ACF4ZO_000631"
                     /gene_synonym="wchF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta 1-4 rhamnosyltransferase Cps2T"
                     /protein_id="HFD5486202.1"
                     /translation="MQDVFIIGSRGLPAKYGGFETFVEELISHQSSKNIRYHVACLSD
                     TKHKVHFDYKGADCFYLNPPKLGPARVIAYDMMAITYALSYSDQHQIQNPIFYVLGNT
                     VGAFIAPFVKQIHNRGGRFFINPDGLEWKRSKWSRPVQAYLKFSEKQMTRQADLVISD
                     NIGIDRYLKQVYPWSKTCFIAYGTQTQPSRLTTADSKVRTYFQTFDISEKDYYLILGR
                     FVPENNYETAIKEFMASSTKRDLVIICNHEGNAYFKQLLAETECDKDPRIKFVGTLYD
                     KELLAYIREQAYAYIHGHEVGGTNPGLLEALAHTNLNLVLGVDFNQSVAKSAALYWTK
                     QKGQLVELINQVDAGFDSDHLGKEAKAIIQEHYTWEKIVGEYEALFLNEH"
     gene            24121..25053
                     /locus_tag="ACF4ZO_000632"
     CDS             24121..25053
                     /locus_tag="ACF4ZO_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFD5486203.1"
                     /translation="MNINILLSTYNGERFLAEQIQSIQRQTVNDWTLLIRDDGSTDGT
                     QDIIRTFVKEDKRIQWINEGQTENLGVIKNFYTLLRHQKADVYFFSDQDDIWLDNKLE
                     VTLLEAQKHEMTAPLLVYTDLKVVTQHLAICHDSMIKTQSGHANTSLLQELTENTVTG
                     GTMMITHALAEEWTTCDGLLMHDWYLALLASATGKLVYLDIPTELYRQHDANVLGART
                     WSKRMKNWLTPHHLVNKYWWLITSSQKQAQLLLDLPLKPNDHELVTAYVSLLDMPFTK
                     RLATLKRYGFRKNRIFHTFIFRSLVVTLFGYRRK"
     gene            25056..25859
                     /locus_tag="ACF4ZO_000633"
     CDS             25056..25859
                     /locus_tag="ACF4ZO_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD5486204.1"
                     /translation="MNFLTKKNRILLREMVKTDFKLRYQGSAIGYLWSILKPLMMFTI
                     MYLVFIRFLRLGGNVPHFPVALLLANVIWSFFSEATSMGMVSIVSRGDLLRKLNFSKH
                     IIVFSAVLGALINFLINLVVVLIFALINGVTISGYSYLSLFLFIELVVLVLGIALLLS
                     NVFVYYRDLAQVWEVLLQAGMYATPIIYPITFVLDSHPLAAKLLMLNPVAQMIQDFRY
                     LLIDRANVTIWQMSTNWFYIVIPYLVPFVILFIGIFVFKKNADRFAEII"
     gene            25859..27064
                     /locus_tag="ACF4ZO_000634"
     CDS             25859..27064
                     /locus_tag="ACF4ZO_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD5486205.1"
                     /translation="MINREIAVKVQHVSKTFKLPTEATKSFRTTLVNRLRGIKGFTEQ
                     HVLKDINFDVYKGDFFGIVGRNGSGKSTLLKIISQIYIPEKGQVTVDGKMVSFIELGV
                     GFNPELTGRENVYMNGAMLGFTKDEVDDMYNDIVDFAELHHFMNQKLKNYSSGMQVRL
                     AFSVAIKAQGDVLILDEVLAVGDEAFQRKCNDYFMERKDSGKTTILVTHDMGAVKKYC
                     NRAVLIEDGLVKAYGEPFDVANQYSVDNTETAEDAMNAEKISVSDIAKDLKVSLISNP
                     RITPNDTITFEVSYEVLKDDFTYIAFSLTDIDRNIWVYNDNSLDYPTQGIGRKCISYQ
                     CQLSQLNDIKLKLEVTVRDKNGQMLLFSTAEQSPQIVIQRNDIDQDDLSALDSASGLY
                     QRNGKWVFH"
     gene            27089..28096
                     /locus_tag="ACF4ZO_000635"
     CDS             27089..28096
                     /locus_tag="ACF4ZO_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFD5486206.1"
                     /translation="MYKVSIICTNYNKAPWISDALDSFLSQVTDFEVEIIVIDDASTD
                     DSREILKSYQKKSSGKIKLLFNETNIGITKTWIKACLYAKGKYIARCDGDDYWTDSFK
                     LQKQVDVLEASKRSRWCNTDFDFVNSQGDLLYANAFSSGHTPLTDTYEKVLALKGMTM
                     ASTWLVDADLMRQVNQKINVDTPDDTFDIQLELFQLTQLTYIKDSTTVYRMTTDSDSR
                     PTDTPKMIHRIQKLLDTQLNYLKKYNQVDTKEVSKLLLQQDAKQEIRIHELSCFIQEL
                     QQTIVDKTKQQETREVELQNVIEEQKNQLSELRQQYHAIINSRQWKYTSKLIAFIRRK
                     K"
     gene            28093..29838
                     /locus_tag="ACF4ZO_000636"
     CDS             28093..29838
                     /locus_tag="ACF4ZO_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnan synthesis F family protein"
                     /protein_id="HFD5486207.1"
                     /translation="MNRILLYVHFNKYNKISAHVYYQLEQMRSLFSKIVFISNSKVSH
                     EDLKRLKNHCLIDEFLQRKNKGFDFSAWHDGLITMGFDKLEEFDSLTIMNDTCFGPIW
                     EMAPYFENFEEKEAVDFWGITNNRGTKAFKEHVQSYFMTFKNQVIQNKVFQQFWQSII
                     EYENVQEVIQHYETQLTSILLNEGFSYQTVFDTRKAESSFMPHPDFSYYNPTAILKHH
                     VPFIKVKAIDANQHIAPYLLNLIRETTNYPIDLIVSHMSQISLPDAKYLLSQKYLNCQ
                     RLAKQTCQKVAVHLHVFYVDLLDEFLTAFEDWNFHYDLFITTDSDIKRKEIKEILQRK
                     GKTADIRVTGNRGRDIYPMLLLKDKLSQYDYIGHFHTKKSKEADFWAGESWRKELIDM
                     LVKPADSILSAFETNDIGIIIADIPSFFRFNKIVNAWNEHLIAQEMMSLWRKMDVKKQ
                     IDFQAMDTFVMSYGTFVWFKYDALKSLFDLELTQNDIPSEPLPQNSILHAIERLLVYI
                     AWGNSYDFRIVKNPYELTPFIDNKLLNLREDEGAHTYVNFNQMGGIKGALKYIIVGPA
                     KAMKYIFLRLMEKLK"
     gene            29835..32309
                     /locus_tag="ACF4ZO_000637"
     CDS             29835..32309
                     /locus_tag="ACF4ZO_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HFD5486208.1"
                     /translation="MIKDTFLKTNWLNIRHHIILLVFSFYFSFYSLAKELVSSTAQPV
                     NYYTHLLNVSFVGYIISLIGLSYYLSRQVSRQLFLKTSFIVISYLIVSYWVQITQHLN
                     DKRFDIWSLTKNQFYQFQALPSLLIILVMATLIKILVAYFAIEKDRFGLLGYQGNTFS
                     VALILAVVPINDIHLLKLISSRFSELVTAGNSQIALLKISGLLIVLLVIFATIIYVVL
                     NALKHLKSNKSSFSVAATTSLFLALVFNYTFQYGVKGDEALLGYYVFPGATLFQIVAI
                     TLVALLAYVITNRYWPTTFFLLILGTIISVVNDLKESMRSEPLLVTDFVWLQELGLVT
                     SFVKKSVIVEMVVGLAICIVVAWYLHGRVLAGKLFMSPVKRASAVLGLFIVSCSMLIP
                     FSYEKEGKILSGLPIISALNNDNDINWLGFSTNARYKSLAYVWTRQVTKKIMEKPTNY
                     SQETIASIAQKYQKLAEDINKDRKNNIADQTVIYLLSESLSDPDRVSNVTVSHDVLPN
                     IKAIKNSTTAGLMQSDSYGGGTANMEFQTLTSVPFYNFSSSVSVLYSEVFPKMAKPHT
                     ISEFYQGKNRIAMHPASANNFNRKTVYSNLGFSKFLALSGSKDKFKNIENVGLLTSDK
                     TVYNNILSLINPSESQFFSVITMQNHIPWSSDYPEEIVAEGKNFTEEENHNLTSYARL
                     LSFTDKETRAFLEKLTQINKPITVVFYGDHLPGLYPDSAFNKHIENKYLTDYFIWSNG
                     TNEKKNHPLINSSDFTAALFEHTDSKVSPYYALLTEVLNKASVDKSPDSPEVKAIQND
                     LKNIQYDVTIGKGYLLKHKTFFKISR"
     gene            32488..33183
                     /locus_tag="ACF4ZO_000638"
     CDS             32488..33183
                     /locus_tag="ACF4ZO_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFD5486209.1"
                     /translation="MKKLIIIPAYNESSNIVNTIRTIESDAPDFDYIIIDDCSTDNTL
                     AICQKQGFNVISLPINLGIGGAVQTGYRYAQRCGYDVAVQVDGDGQHNPCYLEKMVEV
                     LVQSSVNMVIGSRFITKEGFQSSFARRIGIKYFTWLIALLTGKKITDATSGLRLIDRS
                     LIERFANHYPDDYPEPETVVDVLVSHFKVKEIPVVMNERQGGVSSISLTKSVYYMIKV
                     TLAILVVRLKGNR"
     gene            33185..33526
                     /locus_tag="ACF4ZO_000639"
     CDS             33185..33526
                     /locus_tag="ACF4ZO_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2304 domain-containing protein"
                     /protein_id="HFD5486210.1"
                     /translation="MTVTASLFISFIVLTFVFFLINLIKKDKLAIKYSLLWFILALLI
                     LLFTWLPNILNKMSHFLGIHSPTNMLFFLGFCLSLAIIFSLTNNISLQNDKVKRLTQE
                     VALMKKEKTND"
     gene            33519..34805
                     /locus_tag="ACF4ZO_000640"
     CDS             33519..34805
                     /locus_tag="ACF4ZO_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide biosynthesis protein"
                     /protein_id="HFD5486211.1"
                     /translation="MINPSKQNQTIFLWNMLGSLSTAVISVILLMVVTRLLTSADSDI
                     YAFAYSFANMMVVVGLFQVRNYQATDINEKYSFSQYLVARLMTCLLMLAITVIYLTLT
                     KTDSYKSTIVFLVCFYRSTDAFSDLYQGMFQQHERLDIAGKSLAYRNTLIFMVYTAII
                     LYSKNLTLALVAVCIVSLVFIMYYDIGHSKKFQKLMFSELLSNISFQNSLKLLKESFP
                     LFLNGFLIIYIYTQPKYAIELMTTLGEVALGSQTIFNILFMPAFVMNLLILFFRPHIT
                     QMAIALIRGQIKEFNKIQVQLFAYLGVFSLIVLVGSGLFGIPFLSILYGTNLTDYWVD
                     FMLIMLGGSIGSFATVIDNILTAMRKQQLLLIPYTGGFLISLLITNLFVMKYHILGAA
                     LSFLITMLVWLGLSIMIYLFIMNRFKKGRVNATIYD"
     gene            34786..36282
                     /locus_tag="ACF4ZO_000641"
     CDS             34786..36282
                     /locus_tag="ACF4ZO_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2142 domain-containing protein"
                     /protein_id="HFD5486212.1"
                     /translation="MQQSMTKVKYLWKENNNYIYSTFLTLFLTVILYANSLNLPLKFI
                     SLLFVVSTLLIVFLPKKLEVATIIFILAFGTISAIISPINDIPDEYVHYSRTVYISEG
                     DINLTNNNKKLRISKDVDKLIKQSGKTFITSNLKATKHSTREYSYPYIKGTNAYYSFS
                     YIPQALGILVGNALDLPILLTYYFGRLCNLISYAMLAFIAIKLSGSFKQVIAVVTLLP
                     MNIYLAASFNQDGFAIGLVLVTIGLFINLLSSKDKSNYNTKFFLYLVLCGLLVLSKFT
                     YFLLVCLPLFIPNEKFGKNTKLVILKKLGGLLLIFLFAAMWFRLYGQVKTPYVADFLK
                     EVNVSQQVKNMLESPIVYSSIIIRHMVINLINMNNIFQFGALSYGITNLFPLYVCFFF
                     FVYISNASKITINIVEKMGIIFVISAIIGATVLAMYLTWTPVGSSTVLGVQSRYLIGI
                     IPLVLLLFSSQQQKFKQIEDILSDKLAIHVSLLFILAMLMSTIFRYYH"
     gene            36376..37599
                     /gene="pepT"
                     /locus_tag="ACF4ZO_000642"
     CDS             36376..37599
                     /gene="pepT"
                     /locus_tag="ACF4ZO_000642"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0045148 - tripeptide aminopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HFD5486213.1"
                     /translation="MKYDNLLDRFIKYVKVNTRSDPDSETTPSTESQEAFALTILKPE
                     MEAIGLQDVHYNPVNGYLIGTLPANNPTLTRKIGFIAHMDTADFNAENVNPQIIDNYQ
                     GEDITLGSSNYKLDPKAFPNLNNYIGQTLITTDGTTLLGADDKSGIAEIMTAIEFLTS
                     QPQIEHCDIKVAFGPDEEIGVGADKFEVADFEVDFAYTMDGGPLGELQYETFSAAALE
                     VTFLGRNVHPGTAKDQMINALQLAIDFHEKLPAKERPEYTDGYQGFYHLTGLTGTVEE
                     ARASYIIRDFEEASFEARKVKVENIAQSMNAQLGTKRVLVELNDQYYNMKKVIEKDMT
                     AIELAKEVMEELTIKPVIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEFVSLQT
                     MERAVDVIIGLVCKA"
     gene            37640..38128
                     /locus_tag="ACF4ZO_000643"
     CDS             37640..38128
                     /locus_tag="ACF4ZO_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HFD5486214.1"
                     /translation="MIKLFGKIRYHWQPELSWSIIYWSIAFAPIFVGLSLLYERTEIP
                     SRVFILFAIFAVLVGIGLHRYFIIENNGILRIVSFKLFGPRKLLISTITKIEVTKSTL
                     CLHVEDKSYLFYMRKWPKKYFLDALAVNPYFQGEVILSDNFIKLDYFEVYQHDKKALT
                     RG"
     gene            complement(38115..38312)
                     /locus_tag="ACF4ZO_000644"
     CDS             complement(38115..38312)
                     /locus_tag="ACF4ZO_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HFD5486215.1"
                     /translation="MKVSIIPEKCIACGLCQTYSSLFDYHDNGIVTFSSSSETSQSIC
                     PSDKDAILAVKSCPTKALTLE"
     gene            38361..38837
                     /locus_tag="ACF4ZO_000645"
     CDS             38361..38837
                     /locus_tag="ACF4ZO_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAG1386/EF1546 family surface-associated
                     protein"
                     /protein_id="HFD5486216.1"
                     /translation="MAKEPWEEKIVDDTIGTRTRKSRNAFISTPWLTALLSVFFVIIV
                     AILFIFFYTSNSGSNRQAETNGFYGASTHKKTRKASNAKKTSSSSTTTDTTPSSEETL
                     ASSEGTGETLTVLAGEGAASIAARAGISVEQLQALNPEHMTQGYWYANPGDQVTIK"
     gene            38852..39532
                     /gene="cmk"
                     /locus_tag="ACF4ZO_000646"
     CDS             38852..39532
                     /gene="cmk"
                     /locus_tag="ACF4ZO_000646"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004127 - (d)CMP kinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HFD5486217.1"
                     /translation="MKAIKIAIDGPASSGKSTVAKIIAKNLGYTYLDTGAMYRSATYI
                     ALTHGYTDKEVALILEELEKNPISFKKAKDGSQLVFLGDEDVTLVIRQNDVTNNVSWV
                     SALPEIREELVHQQRRIAQAGGIIMDGRDIGTVVLPDAELKIFLVASVEERAERRYKE
                     NLEKGIESDFETLKEEIAARDYKDSHRKVSPLKAAEDALIFDTTGVSIDGVVQFIQEK
                     AEKIVDMS"
     misc_feature    39556..39679
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            39694..40224
                     /gene="infC"
                     /locus_tag="ACF4ZO_000647"
     CDS             39694..40224
                     /gene="infC"
                     /locus_tag="ACF4ZO_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011226065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HFD5486218.1"
                     /translation="MKIIAKKDLFINDEIRVREVRLVGLEGEQLGIKPLSEAQSLADA
                     SNVDLVLIQPQAVPPVAKLMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPVIDKGD
                     FETKLRNGRKFLEKGNKVKVSIRFKGRMITHKEIGAKVLADFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPISDKK"
     gene            40266..40463
                     /gene="rpmI"
                     /locus_tag="ACF4ZO_000648"
     CDS             40266..40463
                     /gene="rpmI"
                     /locus_tag="ACF4ZO_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HFD5486219.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAFTSHRFHGKTKKQRRHL
                     RKAGLVSSGDFKRIKAMVTGL"
     gene            40522..40881
                     /gene="rplT"
                     /locus_tag="ACF4ZO_000649"
     CDS             40522..40881
                     /gene="rplT"
                     /locus_tag="ACF4ZO_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HFD5486220.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVAD
                     AAAFTALADAAKAKLGK"
     gene            complement(41172..43343)
                     /locus_tag="ACF4ZO_000650"
     CDS             complement(41172..43343)
                     /locus_tag="ACF4ZO_000650"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HFD5486221.1"
                     /translation="MKKFKTLITGFINTRLGFIITLLFCYWIKTLWAYHTDFSLDLGN
                     IYQVFLTIINPIPLAFLLLGVALYVKNTRAFYICSWVVYIILNILLISNSIYYREFSD
                     FITVSAMLASSKVSAGLGDSALNLLRIWDIIYILDFIILISLSITKKIKNDQRPFNKR
                     AAFAITALSSLLLSINLFLAEIDRPELLTRGFSNTYIVRALGLPAFTLYSGNQTYQAQ
                     KERNGATAEELIDVKTYVKGHYAAPDPQYFGIGKGKNIIVLHLESFQQFLIDYKLKEG
                     DKEYEVTPFINSLYHSNATLAFPNFFHQVKAGKTSDAETMMENSLFGLNSGSFMVNYG
                     GENTQFATPSILAQKGGYTSAVFHGNVGTFWNRNNAYKQWGYNYFFDSSYFSKQNSKN
                     SFQYGLNDKYMFKDSIKYLEQMQQPFYTKFITVSNHYPYTSLKGESSEEGFPLAKTDD
                     ETINGYFATANYLDAALKSFFDYLKATGLYENSIFVLYGDHYGISNSRNSSLAPLLGK
                     DSETWSEYDNAMLQRVPYMIHIPGYTNGSIKETFGGEIDALPTLLHILGIDTSQFVQL
                     GQDLLSPQNSQIVAQRTSGTYMTPEYTNYSGRLYNTQTGLEITNPDEMTIAKTKEIRS
                     AVAQQLAASDAIQTGDLLRFDTQNGLKAIDPNQFIYTKQLKQLKDISAKLGSESTSLY
                     SKNGHKSTQKLFKAPSYLELNPVEADAATSELKEDNTKNRE"
     gene            43490..44653
                     /locus_tag="ACF4ZO_000651"
     CDS             43490..44653
                     /locus_tag="ACF4ZO_000651"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFD5486222.1"
                     /translation="MNKLYIDSFVEKKLTAGVQLLDEKDFSNIKEKNQLVQLVTKSNR
                     PIGTAYISKQNKGIGWYLGPEKIDLSISYFVSLFSVAKAKRQDFAQSDETNAYRLFNQ
                     EGDGFGGVTIDLYKDFAVFSWYNAFVYDKKEMIMEAFQQVFPEVKGAYEKCRFKGPDT
                     ETAHLYGELAQETFSILENGIAYQVFLNEGLMTGIFLDQHDVRRALVDGLAMGKSLLN
                     LFSYTAAFSVAAAMGGAIETTSVDLAKRSRELSLAHFEHNQLNLASHHFVVMDVFEYF
                     KYAKRKKLIFNVIVIDPPSFARNKKQTFSVSRDYHKLITEALDILSPKGTIIASTNAA
                     NMTVSQFKKQIIKGFGSRRPESMTLQQLPSDFTINKADERSNYLKVFTIKVRE"
     gene            44650..45336
                     /gene="aroD"
                     /locus_tag="ACF4ZO_000652"
     CDS             44650..45336
                     /gene="aroD"
                     /locus_tag="ACF4ZO_000652"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003855 - 3-dehydroquinate dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HFD5486223.1"
                     /translation="MRIVAPVMPRHFDEAQAIDISKYEDVNLIEWRADFLPKDEIVAV
                     APAIFEKFAGKEIIFTLRTVQEGGNITLSSQEYVDIIKEINAIYNPDYIDFEYFTHKS
                     VFQEMLDFPNLILSYHNFEETPENLMEAFSEMTKLAPRVVKIAVMPQSEQDVLDLMNY
                     TRGFKTLNPEQEFATISMGKLGRLSRFAGDVIGSSWTYVSLDHVSGPGQVTLNDMKRI
                     IEVLEMDISN"
     gene            45430..46596
                     /gene="aroC"
                     /locus_tag="ACF4ZO_000653"
     CDS             45430..46596
                     /gene="aroC"
                     /locus_tag="ACF4ZO_000653"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004107 - chorismate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HFD5486224.1"
                     /translation="MRYLTAGESHGLSLTAIIEGIPAGLTLHPADIDHELQRRQGGYG
                     RGARMSIETDRVQISSGVRHGKTTGAPITLTVINKDHQKWLDVMAVGDIEETLKLKRR
                     VKHPRPGHADLVGGIKYHFNDLRDALERSSARETTMRVAVGAVAKRILAELGIDMLHH
                     ILIFGGITITIPSKLSFRELQERALHSELSIVNPKQEEEIKTYIDKIKKEGDTIGGII
                     ETIVQGVPAGLGSYVQWDKKLDAKLAQAVLSINAFKGVEFGVGFDMGFQKGSQVMDEI
                     TWTPTQGYGRQTNHLGGFEGGMTTGQPLVVKGVMKPIPTLYKPLMSVDIDSHEPYKAT
                     VERSDPTALPAAGVIMENVVATVLAKEILETFSSTTMSELQKAFSDYRAYVKQF"
     gene            46657..46998
                     /locus_tag="ACF4ZO_000654"
     CDS             46657..46998
                     /locus_tag="ACF4ZO_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HFD5486225.1"
                     /translation="MSQEIYDYANQLERAVRALPEYQKVLEVKEAIQADASASQLFDE
                     FVAMQEKIQGMMQSGQMPTAEEQTSIQELSQKIEANDQLKAYFEAQQALSVYMSDIER
                     IVFAPLKDLVK"
     gene            47219..48571
                     /gene="gorA"
                     /locus_tag="ACF4ZO_000655"
     CDS             47219..48571
                     /gene="gorA"
                     /locus_tag="ACF4ZO_000655"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004362 - glutathione-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006749 - glutathione metabolic process
                     [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HFD5486226.1"
                     /translation="MVIPYDYIVIGGGSAGIASANRAAMHGAKVLLAEGKEIGGTCVN
                     LGCVPKKVMWYGAQVADILGTYAKDYGFDFKEKAFDFKQLKANRQAYIDRIHASYERG
                     FEQNGVDRIYDYAVFKDAHTVEIAGQLYTAPHILIATGGHPVFPDIEGAQYGISSDGF
                     FALDEVPKRTAVVGAGYIAVELAGVLHALGSKTDLFIRHDRPLRSFDKTIVDVLVDEM
                     AVNGPRLHTHAEVAKVVKNTDESLTLYLKDGQEVEVDQLIWAIGRKPNLEVFSLDKTG
                     VTLNDKGYIETDAYENTSVKGIYAVGDVNGKLALTPVAVAAGRRLSERLFNSKTDEKL
                     DYQNVATVIFSHPVIGSVGLSEEAAVKQYGQEAVKTYQSRFTSMFTAITNHRQPCLMK
                     LVTVGDTEKIVGLHGIGYGVDEMIQGFVVAIKMGATKADFDNTVAIHPTGSEEFVTMR
                     "
     gene            complement(48659..49927)
                     /locus_tag="ACF4ZO_000656"
     CDS             complement(48659..49927)
                     /locus_tag="ACF4ZO_000656"
                     /EC_number="6.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004326 - tetrahydrofolylpolyglutamate
                     synthase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008841 - dihydrofolate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="folylpolyglutamate synthase/dihydrofolate
                     synthase family protein"
                     /protein_id="HFD5486227.1"
                     /translation="MTTYDSISWIHTFKANGRKTDLARMAWLLEALGRPQDKFPAIHV
                     VGTNGKGSVTAYLQHILSTSGYQVGTFTSPFIISFHDRICLNGQPISDLELAQCVSVI
                     RPILTKMSLETNWDRPTEFELVTLIMFCYFANLKPVDIAIIEAGIGGKTDATNVFHAL
                     AVVCPSISFDHQERLGYSLAEIAHQKAEVIKAKEPVIIGQLEQEASQVFQQVTQKAGS
                     RLYQLGKDFLLNPSEKTFSFQHDNLNLTKLRLKLLGQHQKANACLAIMTAQLLRKSFP
                     KISPKTIQKGIEATTWPGRSEFIQPNLLLDGAHNPDSIAKLKSLLQEEFPKRPIHILF
                     AGLKRKPLADLLAQLDTFEVSVTTFDFPEANLLEDYPDKYPQVKDYRDWLQGSVTSDE
                     LFVVTGSLYFISEVRQYCLSNANIFKNIFP"
     gene            complement(49957..50397)
                     /locus_tag="ACF4ZO_000657"
     CDS             complement(49957..50397)
                     /locus_tag="ACF4ZO_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6556 family protein"
                     /protein_id="HFD5486228.1"
                     /translation="MSSRYSRQQKPRKSGGVPTEHIKTGFTAFQKSIALIGSILSIIV
                     ATITISRALQPVPDKTSNDTPKESSNTIVKIIEKESSQGNQNHTGTSETTDDNKTTLP
                     SSSTAPSHNETTPTAPETPSTTEGTQLPNATGAEDANTGLPTNP"
     gene            50632..51774
                     /locus_tag="ACF4ZO_000658"
     CDS             50632..51774
                     /locus_tag="ACF4ZO_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase family protein"
                     /protein_id="HFD5486229.1"
                     /translation="MIYFDNAATTIPYGEALKTYQEVATKIYGNPSSLHQLGTNASRI
                     LEASRKQIAGLLGVKSEEIFFTSGGTESANWAIKGIAFEKTAFGKHIIISAIEHPAVS
                     ESVKWLLTQGFEVSYAPVTTQGVVDVNALAELIRPDTILISIMAVNNEMGAIQPIRAI
                     SNLLANQPTITFHVDAVQAIGKIPLCDYMTNRVDLASFSGHKFHSVRGVGFLYKKAGK
                     RLNPLLSGGGQEQELRSTTENVAGIASMAKALRIVTEKQVSVLPKLTAMRDVIYKALS
                     AYPDVTVFSAQEGFAPNILTFGIRGVRGEVIVHAFEKYEIYISTTSACSSKAGKPAGS
                     LVAMGIPVKTAQTAVRISLDDDNDMGQVEQFLTIFKQIYDKTQKVR"
     gene            51786..53000
                     /gene="thiI"
                     /locus_tag="ACF4ZO_000659"
     CDS             51786..53000
                     /gene="thiI"
                     /locus_tag="ACF4ZO_000659"
                     /EC_number="2.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140741 - tRNA-uracil-4 sulfurtransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uracil 4-sulfurtransferase ThiI"
                     /protein_id="HFD5486230.1"
                     /translation="MDYSEIMVRHGELSTKGKNRMRFINKLKNNIQDVLAPFPAITVR
                     SDRDRTHVYLNGTDYQPVVEALKLVFGVQALSPVYKLEKSVPLLVTAVQDIMTSLYRD
                     GLTFKIATKRSDHAFELDSRELNSLLGGAVFEVLPNIQAQMKHPDVTLKVEIRDEAAY
                     ISYEEIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGLDIEVVHFASPPYTSPG
                     ALAKAQDLTRRLTRFGGNIQFIEVPFTEIQEEIKNKAPEAYLMTLTRRFMMRITDAIR
                     EQRKGLVIVNGESLGQVASQTLESMQAINAVTSTPIIRPVVTMDKLEIIEMAQAIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKLGNAEKYEERFDIDGLVQRAVSGIVVTEITPEIV
                     NDEVENLIDALL"
     gene            53137..54330
                     /locus_tag="ACF4ZO_000660"
     CDS             53137..54330
                     /locus_tag="ACF4ZO_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HFD5486231.1"
                     /translation="MIKTIPYKKTMAAVVALIVALLLFGLIYDLLGVQKNKLAAQKSA
                     QPKVKTARVVANGDILIHDILYMSARKADDTYDFTPYFEYVKDWISGADLAIGDYEGT
                     ISPDYPLAGYPLFNAPEEIAGALKNTGYDVVDLAHNHILDSQLDGALNTKKVFHQLGI
                     DSIGIYDKDRSKESFLIKNVNGIKIAILGYSYGYNGMEATLSQEDYEKHMSDLDEAKI
                     KKELQLAEKKADVTIVMPQMGTEYALEPTAEQKELYHKMIDWGADVVLGGHPHVIEPS
                     ETVIKGRQKKFIIYSMGNFISNQRLETVDDIWTERGLLMDLTFEKKVNKTKIKTVEAH
                     PTMVLAKGKGIVGKEGFELYNYRTMVLEDFIKGGKYHDKIDEETKAKVALAYQEINDL
                     VNLKW"
BASE COUNT        17459 a         9155 c        10911 g        16826 t
ORIGIN      
        1 gaccactatt gaaaatgctg ctcgtgagcc tgaaattgtt gatttagctc aatttttgaa
       61 taaaatggga gctagaattc gtggtgctgg aacagagacg ttaacgataa caggcgtcac
      121 gcatttacga ggcgtagaac atgatgttgt tcaagatcgt atagaagccg gtacatttat
      181 ggttgcagcg gcgatgactt caggcaatgt tttgattaga gatgctgttt gggaacataa
      241 tcgtccattg atttcaaaat taatggaaat gggtgtttct gtaacagaag aagaatacgg
      301 tattcgcgtt caagcaaaca caccaaagct caaacctgta acggttaaaa ccttgcctca
      361 tccgggtttt ccaacagaca tgcaagctca atttacagct ttaatggcag tggtcaatgg
      421 agagtctact atggttgaaa ctgtctttga aaatcgattt caacatctgg aagaaatgcg
      481 acgcatgggc ttacaatctg aaatccttag ggaaactgcc atgattcatg gtggaagaca
      541 actgcaaggt gctcctgtga tgtcaacaga tttacgtgcc agtgctgccc ttatcttgac
      601 agggattgtt gctcaaggag tgacaatagt taataatttg gttcatttag atcgtggcta
      661 ctatcaattt catgaaaaat tagcaaagct tggagctact attagtcgta gcagtgaggt
      721 ctagcttatg acaaatggtt taaaatatgt cttagaacaa atgttattac ttttagtaat
      781 tgctgccttg gcgtgtcttt ttttagccat tggacttatg attggttata gttttatggg
      841 agatggccag agtccatggc atattttatc tatggataag tgggcagagt tagtgaataa
      901 atttactgga aagtaggcct agcctacttt ttatagcatc tgagaggata tatgttagca
      961 aagaaaaaac gaaaaagggt gcttaattcc ttcttattga ttttgttagt gttggggtct
     1021 aactgccttg ctaagagtga tttcatagct agcaatcacc ctatcaagca actttatcag
     1081 actcttgttg gggagaagaa aaaatcatta ctcacacata ataatttgcc cgctgatgtt
     1141 cccacagaag ctctggcggc atcggtatta acaccatcaa tcaaaaagca actaggtcca
     1201 gatgttcagt ggaatggagc aggcgcctat attatcaaca ggaacaaaac agatttaaat
     1261 gctaaggtag ccagtctgcc ctatgccaac aatgaaacca aatgggtgca agagcaaaag
     1321 gttcctaaaa gagctaatgc cttacttact aagtcgacac gacagtatcg aaatcgctat
     1381 caaacggaca atgcttatcg taactttaag ccagcaggtt ggcaccgatt gcaccgctta
     1441 aaaggaagtt atgatcacgc ggttgataga gggcatttgc taggttatgc tttagttggt
     1501 ggactgaaag gtttagatgc ttctaccggt aatcctgata atattgccac tcaactaagt
     1561 tgggctaatc aagcaaataa accctactcg acaggtcaga attactatga aggtttagta
     1621 tgtcgtgctt tggataaggg gcatcgcgtc cgctaccgtg tcaccctact ttatgatggt
     1681 gataatctac tagccagcgg tagccatttg gaggctaaat cctctgatga cagcttgact
     1741 tttaacgtgt ttgttccaaa tgtccaacca ggattgaccg ttgactatag gacgagacaa
     1801 atagctatca atctctaagc gaaaagtcac tgatttaaga ttgtcactaa gcactttttt
     1861 tgatagaata gaactaattg aataagtgtc tatgagacta gtactaatag agaaattaac
     1921 agggagtgag ggccgtgact ggaagccttc ttaagggaac tattaggaat tcactcagct
     1981 aaagacaatt aattaaggtc tgataacatc agataaaaac ggatggtacc gcgtgtcaac
     2041 gctccgctta tcaagtggag gagtggcacg cttttttcat cgctaaaaga agggaaaact
     2101 atggatttac aagcacaatt agaggaatta aagacaaaaa cattggagac cttacagtct
     2161 ttgacgggta atcataccaa agaactgcaa gatttgcgcg tggctgttct tgggaaaaag
     2221 ggatctttga cagaattact aaaggggcta aaagacttgt ctaatgactt gcgtcctgtg
     2281 gttggtaaac aggtgaacga agttcgtgac ttattgacaa aagcctttga agaacaggcc
     2341 aaaattgtag aagctgctaa aattcaggcc caacttgatg ctgaaagcat tgatgtgact
     2401 ttaccgggtc gtcaaatgac tttgggccac cgtcatgtgt taacacaaac cagtgaagaa
     2461 atcgaagata ttttcttagg aatgggtttt cagattgttg atggctttga ggtggaaaaa
     2521 gattattaca actttgagcg catgaatttg ccaaaggatc atcctgcccg tgacatgcaa
     2581 gatacgtttt atatcacaga agaaatcttg ttacgaactc acaccagtcc tgtgcaggcc
     2641 cgtactcttg atcaacatga tttttcaaaa gggcctttaa aaatggtttc tccaggtcgt
     2701 gttttccgtc gtgatactga tgacgctacc cactcacatc aattccatca aattgaaggt
     2761 ttggttgtgg gcaaaaatat ttctatggga gacctcaaag ggactcttga aatgatcatc
     2821 aagaagatgt tcggtgaaga acgtagcatt cgtttgcgcc cgtcatattt cccgttcaca
     2881 gaaccatctg ttgaagtgga tgtttcttgc tttaaatgtg gtggaaaagg ctgtaatgtc
     2941 tgcaagaaaa caggatggat tgaaattctt ggtgctggta tggttcaccc aagtgtcttg
     3001 gaaatgtcag gtgttgatgc aaaagagtat tcaggctttg cctttggttt aggtcaagag
     3061 cgaattgcca tgttgcgtta tggcattaat gacattcgtg gtttctatca aggcgaccaa
     3121 cgtttctctg aacaatttaa ctaaaacgag tcgtttgaag acctctgtca gctattttat
     3181 ctaagattga gtgaaagttg ataggtaatg ataataggtt aattgtctaa ggagaaagtc
     3241 cctctcgctt caacgtcata agggttttga cttggaactt aaaatacgaa aggaaatgac
     3301 tcaaatcacg gcttgagagc tttctctagc cgagtgattt gggcactaaa attatgttag
     3361 tatcttataa atggttaaaa gaattagtag atatcgatgt gacaccagca gcacttgctg
     3421 agaaaatgtc gacaacgggt atcgaggtag aaggaattga agtccctgca gaaggtttat
     3481 caaaactggt tgtggggcat gtgctttctt gtgaagatgt gccagagaca catttgcatt
     3541 tgtgtcaggt agatacaggt gatgaaacgc cacgtcaaat tgtgtgtggc gcaccaaatg
     3601 tgaaagcagg gattaaggtt atcgtggctg tgccaggtgc tcgtattgca gataactata
     3661 aaatcaaaaa aggcaaaatc cgcggcatgg aatctcttgg catgatttgt tccttgcaag
     3721 aacttggttt gtcagatagt attattccaa aagaattttc agacggtatt caaatcttgc
     3781 cagaggaggc tgtgccaggt gatgctattt ttaaatacct ggacttggac gatcatatca
     3841 ttgaattgtc cattacacct aaccgtgctg atgcgctttc tatgcgaggt gtggcacatg
     3901 aagtcgcagc tatttatggc aagtcagtat cattccccca aaaaaatcta caagaatctg
     3961 ataaggcaac ttcagaagcc attgaagtgg ccattgcctc tgataaagtt ctaacttacg
     4021 ctagccgtgt cgttgaaaat gtcaaagtta agccaagtcc acaatggttg caaaaccttt
     4081 taatgaatgc tggtattcgt cctattaata atgtggttga tgtgaccaac tatgtgctct
     4141 tgtattttgg tcaacctatg catgcttttg attatgataa atttgaagac cataagattg
     4201 tggcgcgtgc ggctcgtcaa ggggaaagtt tagtcacact tgatggtgaa aaacgggatt
     4261 tgaccactga ggatcttgtt attaccgtgg ctgacaaacc agttgcttta gcaggtgtta
     4321 tgggtggtca agccactgaa attgatggca actctcagac ggttgttctt gaagctgctg
     4381 tttttgatgg caaatcgatt cgtaaaacca gtggtcgttt aaaccttcgt tcggaatcct
     4441 cttcacgttt tgaaaaaggg gttaactatg caactgtttt agaagcgctt gactttgcag
     4501 cggctatgtt acaagaatta gcagaaggtc aagtcttatc aggtcatgtt caagctggac
     4561 aattgccaac agaacctgtt gaagtctcaa ctagccttga ctatgtgaat gttcgtttag
     4621 gaacagaatt aacttttgct gatattcaaa ggatttttaa ccaacttgga tttggtctaa
     4681 caggagatga aacaagattc acggtagctg ttcctcggcg tcgttgggat attagcatcc
     4741 cagctgactt ggtggaagaa attgcgcgta tctatggtta tgataagttg ccgacaacct
     4801 taccagaggc aggaggaaca gctgcagaat taacgccaac acaggctctt cgtcgtaagg
     4861 tccgtggttt agcggaagga ttgggcttga ctgaaatcat ttcgtatgcc ttgacaacac
     4921 cagagaaagc tatcgagttt gcagtggcac caagtcacct aacagaactc atgtggccaa
     4981 tgtctgtgga acgttcagcg cttcgtcaaa atatggtttc agggatgtta gatacggtag
     5041 cttataatgt ggctcgtaaa caaagtaact tggctcttta tgaaattgga aaaatctttg
     5101 aacaagaagt taatccaaaa gaagaccttc ctaatgaagt gaaccatttt gcttttgcta
     5161 tttgtggctt agtggcacaa aaagatttcc aaacccaagc tcaggcagtg gatttttacc
     5221 atgctaaagg tatcttggat actttatttg caaaccttaa cctcaaggtt caatatgtgc
     5281 caaccaaaga cctagcaaac atgcacccag gacggacagc gcttatccta ttagatgagc
     5341 aagtgattgg atttgttggt caagttcatc caggaacagc aaaggcttat agtattccag
     5401 aaacctatgt ggcagaattg gatatggctg ctttagaagc agcgttgcca agtgatcaaa
     5461 cttttgtgga gattaccaaa ttccctgcta tgacacgtga tgttgccttg ttacttgacc
     5521 gtgaggtgag tcatcagacc attgtaacag ctattgaatc agcaggtgta aaacgcttga
     5581 ctaagattaa gctctttgac gtgtatgaag gagcaaccat tcaggctggc caaaaatcaa
     5641 tggcttatag ccttactttc caaaatccaa atgacaattt aacggatgaa gaagttgcca
     5701 aatacatgga gaaaatcacc aaatcattga cagaacaagt cggtgctgaa gtacgttaag
     5761 aaaaaggaac tgagcctcaa aagctcggtt cttttctgtt ataataggat aagaagcaac
     5821 tccagttcaa atgattggag aaaaacatca gaaggtggag gaaaatcaga atgtatcaaa
     5881 caaaaataac aggcaaccgc ctttaccaca cggtttcgaa aggctacgga gatagtgtga
     5941 ccttatttgg aaaaactgat caaggggaaa cccctatgag tttactggtt attgccttgt
     6001 cttcttgtgt gactatgtgt gtgcagggtt tttaccatcg tcaatttcag caagacacac
     6061 ttgctgtttc tgctgaggct agttatgagg aagaagtttt tgaactactt gttaggattg
     6121 atgatgtttt agatgacaaa aagaaagctg atttgttggc ttacattgga gcttattgtc
     6181 gtgtgaaaca actcctcaaa cctgaagtta cggtgaccat tacgttggaa ggactgtctc
     6241 atgtctgatg ctagtttgaa aacttaccaa aaacaatggg cttatcaaaa gtattgggtc
     6301 atggcacact cacagcagca ttacaatgct ttaagagaat tgtttaaagg aaatcagtgg
     6361 tcagaagaaa aggtgttgac ttttcattgt ttgattgaag aagcgcaagc cattcctccc
     6421 acagtaaaaa gcttacgaac ggcatatcag catgtttggg ggtattttaa aaaggtagcg
     6481 agtcaggaag aaaaagacca tttcaaagat ttggatgctc agttggaaac taaatctgag
     6541 gagatgctat gctttttaca agagatgacg gctcattatc agccctctta tctgctatct
     6601 tgccgtttga ttaccaaagg tccttaaatg ctaaacagaa aagtagggac ttctgggaag
     6661 ttatgctaag ctagtgatat aaacaaggga gaatgagaga tgtttttagc gcttaatgaa
     6721 atgaaacaat ccaaattgcg gtatggtttg attgctggtt tgctatgttt ggttgcctat
     6781 ttgatgttct ttttgtcagg attggccttt ggtttgatgc aggagaaccg ctctgcggtt
     6841 gatctttgga aagctgacag tgttttactg gccaaggatg ctgacgctac cttgacctta
     6901 tcacaggtgt ccagagctca agaaaatcaa ataacagcag acaaggtagc tcctcttgct
     6961 caactcaata ccgtggcgtg gtcagttaaa aatcctaagg atgccgacaa agttaaggtt
     7021 agccttttcg ggattgattc taatagcttt attcgtccta acattgtaaa aggtcgatta
     7081 tttaagacta acaaagaggt tgttttagat caaagccttg caaaagagga agcttttgcg
     7141 attggcaagg acttttacac atcgagttct agtcaagcat taactatcgt tggttatact
     7201 caaaatgcta gatttagtgt tgcaccagtg gtttatatga atctggaagc ttttgaaaca
     7261 ttaaaatatg gagaaccact accaaaagat aagcaagttg ttaatgcttt tatcactaaa
     7321 ggaagtttaa tagattatcc taaaaaagac ttccaaaaat tagatattaa aacctttatt
     7381 actaaattac ctggttatag cgctcaactt ttaacgtttg gctttatgat tagttttctt
     7441 gtcattattt cagctattat tattggtatt tttatgtata ttttgactat tcaaaaggca
     7501 cctatttttg ggattatgaa agcgcaagga atttctaaca aaacgattac gaccgctgtg
     7561 cttatgcaga cattcttttt gagtttttta ggtagtggtt tagggttgct aggtacttgg
     7621 ctgacatcat tattattacc aacagtagtt ccttttcaaa gcaattggtt tttatatttg
     7681 gctatattcg ttagtatgat ctgttttgct ctattaggca ccttattttc tgtttttaac
     7741 attatacgaa ttgatccttt gaaagcaatt ggataggagg tagtgatgtc ggttttaaca
     7801 tttaaacaag tgatcaaaac atttcaagat ggtcatcacg aaatcaacgc attaaaggca
     7861 actgactttt ccattgaagc tggagaattt gtggctatta ttggaccatc aggttctgga
     7921 aaatcaacct ttttgaccat tgctggtggc ttacagaccc caagttctgg tcagctaatc
     7981 attgatggca ctgattatac gcatttatca gaaaaagagc gctcacgctt gcgcttcaag
     8041 tccgttggtt ttatcttaca agcttccaat ctgatacctt ttttaacagt ccagcagcag
     8101 ttggaattgg tcgatcattt gacaggaagc aaagaaaaag ccaaagccaa tcagttattt
     8161 gacgatttag gcattacagg gctaaaacat cagttacctc aagaattgtc cggcggagaa
     8221 aggcaaagag cggcgattgc ccgtgctctc taccatgatc cagcactgat attggcagac
     8281 gaacctactg caagtttgga tactgaaaaa gcctatgaag tggtcaaact gttagctaag
     8341 gaaagtaaag aaaaaaacaa ggccattatt atggtcactc atgatgatcg gatgctagaa
     8401 tattgtgaca aagtctatcg gatgcaagat ggagagttac gtcaagagag atagtagact
     8461 ggtaagagtt tatgatatta gaagaaaaaa accaaacaag cacagcactt gtttggtttt
     8521 tttctaagtg tgactattat caatacgtca ccatttccct aaagcttact atacgggatg
     8581 ctaaaggtat caccatgctc aaagtcgcca tattggtaac ctcggtcaaa ccaacgttgg
     8641 cgttgcttag aagtgccatg tgtaaaacta tcaggaacgg ttctgccata ggtttcttct
     8701 tgcagagtat catccccaac tgcgtgagct gctgccattg cctcctcaat gtctcctttt
     8761 tccaaaaggc cttgcccttg aacataatta gcccaggcac cagcatagta atcagcttgt
     8821 aattccaact tgacgttgag ttgattggct ttagcctttg attttccttg tctagcgcta
     8881 gcgtaattat ccataattcc caattcattt tggatgtggt ggccaacttc atgagcaatc
     8941 acataggcca tagcaaaatc accttttgcg ccgtacttgg ttgatagttc attataaaaa
     9001 gaaatatcta aatacacttt ttgatcgcct gggcaataaa aaggaccaga agaggcttga
     9061 cccctgccac aagcggtttg agttgctcca gtatatagaa ctaatgttgg tttatgataa
     9121 gttaaccctt tctcacgaaa tgtcttagtc caatagtcct cggtagaggc gaagacctta
     9181 ctgacaaaag aaacctgttc ttgactagcc ttgtcaccat ttgtacgcgt tacttggctt
     9241 gattgatagg cattgttgtt ggtagaagaa ggcttgcctc ctaaaacacc agataggcca
     9301 ccccctccca taactaggag aaggagaaga ataaccagct tggttttcca acctcctcgt
     9361 gaaaagagta attgaagcag gagaccgccc cctaggccgc cgcccccaaa agaaccagac
     9421 gattgaccac gtctatcttc aacctgttga ctttctctca aatcatccgt tttcataaat
     9481 ttctcccatc tatttcttga ttttattata aaataattct attagaattg ctatttttat
     9541 gatgagatta taactaaaaa taggaaaagc aataggtatt tgctataata taacaagggt
     9601 agattcagtt tgtataaagg agtcatatga aattaattta cacagagatg agttactcga
     9661 tgacagagat tttggtgaat gaagcacgaa aagctgctga ccaaggttat cgagtgttct
     9721 atattgctcc aaattctctt tcatttgaaa aggaaagaga agtcttaacc ttattgcctg
     9781 aacgagggac tttttcgata atagtcaccc ggttcgttca aatgtcaagg tattttacag
     9841 ttgagagctc tccttctaag caacatctag atgacacgac tttggctatg attttttatc
     9901 gggccttgat gcaattaaaa ccagaagatt tgccgagtta tggtcgtttg caaaataatt
     9961 cggtttttat tgaacaacta gttgagttat ataaggaatt aaaaaacgca caattaagcg
    10021 tacatgattt aacagggtta gaccatcctc aaaaacaaga agatcttatt aaaattattg
    10081 agcttgcaga gacgatcatg attcagcaag attataatca agatagtcct ctacaatctt
    10141 ttgcaagagc aattaagtta ggacttttaa ataaccaact atcaaaaaca gttgttgtta
    10201 ttgatggttt ttcacgtttt tcagctgaag aggattattt attatcactt ttaaataaca
    10261 actgtcaaga ggtcatcact ggcagttatg tgagtcaaaa agcttatcaa aaatctttta
    10321 ttaagggaaa tatctatgag gctagccttc attttttgca agatttggct caaaaatacc
    10381 atatcaagcc ggtatttgcg acctctaatc aagtgtttaa accagccttt tcacggctaa
    10441 cacaattatt tgaagcaact catgattttt cacaagtaga ctggcaattc caaaagaatg
    10501 atcttgatca ctttagcctt tggcaatgtc atcatcaaaa agaggaaatt gaacatgtag
    10561 caaaatccat tcggcaaaag ctatatgaag gttaccgtta taaggatatc ttagtgttgc
    10621 taggagatat ggatgcttat caattacaaa ttgggcctat ctttgataag tttgaaatcc
    10681 cctactattt aggaaaagca gagcctatgg ctgcccaccc attagtccaa tttatagaat
    10741 cgctcgaacg aagtcagcgc tataattggc gtcgtgaaga cattttaaac atgttaaaat
    10801 caggactttt tggttgtttt gatgatagtg atattgatcg ctttgaggaa tatactcagt
    10861 ttgcagatat taaagggttt actaaatttt caaagccttt taccattaac tcttctaggc
    10921 agtatcctct tgacttttta aatgaaatga gacaagacat cgttttacct ttgcaagaat
    10981 tgtttaagag tcaaaaacaa cttggtgctt cacttgttga caaattaata ctttttttaa
    11041 aaaagattag attagctgag aatatgcaag gtttagcaca gtcccaatta gaggtggaaa
    11101 aaaacgaaga agtttggaaa aggtttacag atattttgac ttcttttcat catatctttg
    11161 gccaagaaaa attacgacta tcagattgcc ttgctttaat caaaacagga atgaaatcag
    11221 ctcagtatcg tgttgttcca gcgacattag atgttgtcac cattaaatct tatgaccttg
    11281 ttcaaccaca ttcaaaacct ttcgtttatg caattggtct aactcaatca cattttccta
    11341 agcaaattca ccattcagga ctactttctg atcaagagcg tgctagaatt aatgaaataa
    11401 gaaattatcg tcattttgat attgctagtg ccgaaaatag taaaaaaaac catcaaactg
    11461 cgttatctct gtttaatgct gccactaagg agttagttct tagtgttcca acggtaatca
    11521 acgagacatt cgatgatcta tctccttatc ttaaagaatt aataaacttt gggttacctc
    11581 ttttggataa aggcaaaaac tatctatctt atgataatag cgatattggt aactataaag
    11641 ctctcttgtc acaaattatt gctattaacc gacaagatct tatagaaatg tcagatcaag
    11701 ataagatgtt ttggactgtt gtcttacgtt atctcaggaa acagttaaga aagcaacagc
    11761 tagagttacc tacttcagat tatcgtttat caacaaagtc tttgtctaaa gaagttatcg
    11821 aggtatgttt tccaaaggga atccctttaa agctatctgc aactgcttta accgtttttt
    11881 ataataatca gtacaactat tttttgaaat atgttttgaa tttaaacaaa acagaatcca
    11941 ttcatccaga ttccagaatt catggtcaat acttgcatcg tgtctttgag cggttaatga
    12001 aagatcacac gcaagaaccg tttgataata aattaaaaca agcaatctac cataccaatc
    12061 aagaaagttt ttttcagcag gtttaccaag ataatgccga ggctgagtac agtttagcta
    12121 tactagaaga tattgttaga tcaacagcac ctatcttgca acttaaccaa aacataaagg
    12181 tcattgatca agaaaagaat tttcatctgg atatgggaaa tgagatatta gtccacggga
    12241 tcattgatcg tattgaccag ctgagcgacg gtagcttggg cgttgttgac tataaatcaa
    12301 gcgcgaatca atttgatatt gggacttttt ataatgggtt gagtccacaa ctagtgactt
    12361 acctcgcagc cttaaaacag atcgcaccac acgatataaa ccaattattt ggggctatgt
    12421 accttcattt gcaagatcct aaattggatc tagtaacatt taaacaaatt gataacacat
    12481 tagtggagag tatctataaa gcgttgacct ataaaggtat tttttcagaa gtcgaaaaag
    12541 agcatctatc tactggtgct taccaaacca aaaatgctct ttattccaat gacgaattgg
    12601 aaacactttt aaattataac aagtacctct atcttaaagc tgttaaacac attaaaaagg
    12661 gacatttttt gattaatcct tatacaagcg atggtaagac agttcaagga gatcaattaa
    12721 aagccattac ccgttttgaa gcagatcttg acatggcaca ggcaaggcga ctagtgactc
    12781 tccctgctaa ggagaaaaaa gagtgctttt taacattaat gagaaaggag agccacttgt
    12841 gatttctttt gccccatttt taagccccga agctattaaa tatttacaag aaaacgaaag
    12901 gtgcagtgat cagtctcaaa aacgcacagc tcaacaaatt gaagcaattt atactagtgg
    12961 ccaaaatata cttgtatcag cttctgctgg ttcaggaaaa acctttgtaa tggtcgaacg
    13021 catacttgat aaaattttga gaggtgtttc aattgatcgg ctttttatct caacctttac
    13081 tgttaaagca gctacagaac tgcgtgaacg gattgaaaac aaattatact cacaaattgc
    13141 tcaaactaca gattttcaaa tgaaagttta tttaacagaa caattgcaat ctctttgtca
    13201 agctgatatt ggtactatgg atgcttttgc acagaaagta gtaagtcgct atggttatag
    13261 cattggcatt tcatcccaat ttcgtatcat gcaggataaa gcagaacaag atgttttaaa
    13321 gcaagaggtg tttagcaaac tctttagtga gtttatgaat caaaaagagg caccggtgtt
    13381 tagggctctt gtgaaaaatt tttctggtaa ctgtaaagac acttcagctt ttagagagtt
    13441 agtttatact tgttattctt ttagccaatc gacagaaaat ccaaaaatat ggttgcaaga
    13501 aaattttcta agcgctgcta aaacttacca aagacttgaa gatatcccgg atcatgatat
    13561 tgaactctta cttttggcaa tgcaagacac tgcaaatcag ctaagagatg tgactgatat
    13621 ggaagattat gggcagctga ctaaggcagg tagccgatct gctaaataca ctaaacactt
    13681 aacgattata gaaaagttgt ctgattgggt gcgtgatttt aaatgtttgt atggaaaagc
    13741 cggattggat cggttgatca gagatgtgac aggccttata ccatctggga atgatgttac
    13801 agtctcgaag gtaaaatacc ctgtttttaa gaccttgcat caaaaattaa aacaatttag
    13861 gcatttagaa acaattttaa tgtatcagaa agactgtttt cccttattgg aacagttaca
    13921 agattttgtg cttgcgtttt cagaagctta tttagctgtc aaaatacaag aaagtgcttt
    13981 tgaattttca gatattgcac actttgcaat caaaatttta gaggaaaata cggatattcg
    14041 ccaatcctat cagcaacact atcatgaggt gatggttgat gaatatcaag ataacaatca
    14101 tatgcaagag cgactcctga ccttactatc gaacggtcat aatcgcttta tggtaggaga
    14161 tatcaaacaa tcgatctatc gatttcggca agccgatcct cagattttta atcaaaagtt
    14221 tagagactat caaaaaaaac ctgagcaggg gaaagtgatt ttactcaaag aaaactttcg
    14281 tagccaatca gaggtgttaa atgtcagcaa tgctgttttt agtcacttaa tggacgaatc
    14341 agtaggagac gtcttatacg atgagcaaca tcagttaata gcaggtagtc atgctcaaac
    14401 agtcccctat ctagaccgtc gtgctcagtt attgctatat aatagcgata aagatgatgg
    14461 caacgcccct tcagatagtg agggtatttc atttagtgag gttacaattg ttgccaaaga
    14521 aattattaag cttcacaatg ataagggtgt cccttttgaa gacattacgt tactcgtttc
    14581 ttcaagaaca agaaatgata tcatttctca tacattcaat caatatggta ttcctatagt
    14641 aacagatggt gggcagcaaa actatcttaa atctgttgaa gtgatggtta tgttagatac
    14701 attacgcacc attaataacc caagaaatga ttatgccctt gtggctttac tgcgctcacc
    14761 gatgtttgcc tttgatgagg atgatttagc aagaatagca cttcaaaaag acaatgagct
    14821 agataaagat tgcctatatg acaagataca aagggctgtg attggaagag gtgctcatcc
    14881 tgaattgatt cacgatacct tgcttggcaa gttaaatgtt tttttaaaga cgttgaaaag
    14941 ctggcgtcga tacgctaagc tagggtcgtt gtatgacttg atttggaaaa tttttaatga
    15001 tcgtttttat tttgattttg tagctagtca agcaaaagca gaacaagcac aagctaatct
    15061 atacgcatta gctctacgtg ctaatcagtt tgaaaaatcg ggctataaag ggctataccg
    15121 ttttattaaa atgattgata aggtacttga gacgcaaaat gacttagctg atgtggaagt
    15181 ggctgctcct aaacaagctg ttaatttaat gaccattcac aagtctaaag gtttacaatt
    15241 tccgtatgta tttatcctta attgtgacaa gcgcttctca atgacagata ttcataaatc
    15301 atttattctg aatcggcagc acggtatcgg tatcaagtac cttgcagata tcaaaggttt
    15361 acttggtgaa acaacactca attctgttaa agtaagcatg gaaaccttac cttatcaatt
    15421 gaacaaacaa gagttgcgct tagcaacttt atcagaacaa atgcgcttac tgtatgttgc
    15481 tatgacacga gctgaaaaaa aagtttattt tattggtaaa gctagtaaga gcaaaagtca
    15541 agaaatcaca gatcctaaaa agttaggcaa acttttgccg ctggctttac gagaacagtt
    15601 attgacattc caagattggc tattagcaat agcagatata ttttcaactg aagatcttta
    15661 ttttgatgtt cgctttattg aagatagtga tttgacacaa gagtcagtcg gacgacttca
    15721 aacaccacag ttattaaatc cagatgatct taaagataat cgtcaatcag aaacaattgc
    15781 acgggcttta gatatgttag aagcagtgtc tcaattgaat gccaattatg aagcagctat
    15841 tcatttgcca acagttcgaa ctcctagcca acttaaggca acttacgagc ctttattaga
    15901 acccattggt gtagatatta tagagaaatc ttctcgatcg ctatctgatt ttactttgcc
    15961 acatttttca aaaaaagcaa aagttgaagc aagtcatatt ggatcagctc ttcatcagtt
    16021 gatgcaggtg ctccctttgt caaaaccgat aaatcaacaa acgcttttag acgctttaag
    16081 aggaattgat agtaacgaag aggtaaaaac agctcttgat ctcaaaaaaa tagagtcgtt
    16141 cttttgtgat acaagcctag gccaattttt tcagacttac caaaaacact tgtatcgaga
    16201 agcgccattt gctattttaa aacttgaccc tatcagtcaa gaagaatatg tcctacgtgg
    16261 tattatagat gcctactttt tgtttgatga tcatattgta ttagtggact ataaaacaga
    16321 taaatacaag cagcccattg agttaaaaaa gcgttaccaa caacagttgg agttatatgc
    16381 agaagctctc actcaaacgt ataaacttcc tgtgactaag cgctatcttg ttttaatggg
    16441 aggtggaaag ccagaaattg tcgaagttta aggttgttgt gacacaaggg tgttttgcaa
    16501 atgataatag tatagttgag gattttacga aatgtttgaa aagctattga cctttgaata
    16561 ataatacaat ataataagtt ttattagtga caaaaaggaa taaatatact atgaatttta
    16621 aaaaaataag atttggtttt ttgctttgcc tcctacttta tcctttggca gcttgtaaca
    16681 agtctgaaca acttaatcac tacgaaagaa ttaaaaaaac aagaaaatta gtcgttgctg
    16741 taagccctga ttatgctcct tttgaattta aagctttagt taatggaaaa gatactattg
    16801 ttggagcaga tgttcaatta gctcaggcta ttgctgatga attagacgtt gatcttgagc
    16861 tttcaccaat gagttttgat aatgttttgt ctagtttaca gactggtaaa gctgatcttg
    16921 ctatttcagg aatctcacat actaaagaaa gagctaaagt atatgatttt tcaattcctt
    16981 actatcaggc agaaaacgct atagtgatga gagcatctga tgctaaagtg accaaaaata
    17041 ttagtgacct aagcggtaag aaagtagccg ctcaaaaagg tagtatcgag gaaggtttag
    17101 ttaaaataca attaccaaag gccaatctga tttctttgac tgctatggga gaagccatta
    17161 atgaactaaa agcaggacaa gtctatgcag ttaccttaga aacacctgta gctgctggtt
    17221 ttttagccca acataaggat ctggctttag caccctttag cttaaaaacc agtgatggag
    17281 atgccaaagc agtggccctt cctaaaaata gtggtgactt aaccaaagcc gttaataagg
    17341 ttattgctaa gttagatgag caagaacggt acaagtcatt tattgcagag acaatagcac
    17401 taacgaaaaa tactatgaag taataaggtt aataaaaact ttattagtat ccgttggaaa
    17461 agtgtttgga ataaacaata aaagaggttt gacttttttt aaaaaataat gtaatataat
    17521 tgggaacgtg aaaatgttac aatatcttga ggaggtgaaa cacatgtcaa aaacagtagt
    17581 acgtaagaat gaatctcttg acgatgctct tcgtcgcttc aaacgttctg ttactaaagc
    17641 tggtactctt caagaatcac gtaaacgtga attctacgaa aaaccttctg taaaacgtaa
    17701 acgtaaatca gaagcagctc gcaaacgtaa aaaattctaa tgataaaaaa taaaaacagt
    17761 tctcacaatt agaactgttt ttatttttta tccagaagaa gcaagggagc ttttttgata
    17821 tcaaaaaagc agttagacat gcctaactac tttatcaaaa atcgctttat ttttgagcca
    17881 acaaatcacg gatttctgtc aataattctt cttgagtagg agctgcagct tctttttctt
    17941 ttttaggcat agctttttca gcggctttta caacaaagaa aagactggta ccgatgataa
    18001 gaaaattaat aacggctcct aaaaagctac catatttaac accattccat gacaattgag
    18061 tgatgttttc aacatttgca gctttcagag ctgggtttaa aataagcggt gtgataatat
    18121 cgttcacaaa agaagtgaca atagcaccaa aagctccccc gatgataact gctacagcaa
    18181 gttcaataat gtttcctcta aacaaaaatg cttttaattc tttaaccatt aaatattccc
    18241 ccttttaata tctctaagtt aagcatagca taattagtaa acaaaatcca atggaatcac
    18301 ttcagttttt aaatttacaa aaaagagttt cggtggtata ataaaacgta aaactaaaat
    18361 gggattttta tggggaggtg acgatttggc aattgacaaa gaaatgattt cccaagtaaa
    18421 aaatagcgtt aatatcgtcg atgtcattgg agaagtggtc aaactttccc gatcagggcg
    18481 gcattatctc gggctttgcc catttcataa ggaaaagaca ccctctttta atgttgttga
    18541 agacagacaa ttttttcact gctttggctg tggaaaatca ggggatgttt ttaaatttat
    18601 tgaggaatac cgccaagtcc ccttcttaga aagtgttcag attattgccg ataagactgg
    18661 tatgtcgctt aatatatcgc caagtcaggc agtaattgct agccaacaca agcaccctaa
    18721 tcacgctttg atgacacttc atgaggatgc tgctaaattt taccatgcag ttttgatgac
    18781 cactaccatt ggtcaagaag ctaggaagta cctttaccag agaggcttgg atgaccaatt
    18841 aattgagcat ttcaatattg gtttagcccc agatgagtca gattatcttt atcaagctct
    18901 ttctaaaaaa tacgaggaag gtcaattggt tgcttcagga ttgtttaact tgtccgatca
    18961 atccaatacc atttacgacg cctttcgaaa tcgtatcatg tttcccttat cagatgaccg
    19021 agggcatatt attgcctttt caggacgtat ctggacggca gctgatacgg aaaagagaca
    19081 ggccaagtat aaaaattcaa gaggaacagt tctttttaac aaatcttatg aattgtatca
    19141 tctggacaag gcaaggcctg ttattgccaa aacccatgaa gtgtttctaa tggaagggtt
    19201 tatggacgtg attgccgctt accgttccgg ctatgaaaat gctgttgctt caatggggac
    19261 ggcattgact caagaacatg tcaatcacct taagcaagtc actaaaaaag ttgttttgat
    19321 ttatgatggt gacgatgctg gacaacatgc tattgcaaaa tcactagaat tgcttaaaga
    19381 ttttgttgtc gaaattgtca gaatccccaa taaaatggat cctgacgaat ttgtacaacg
    19441 gcattcccca gaagcatttg cagatttgct taagcagtca cggatcagta atgttgaatt
    19501 ttttattgat tacctaaaac ctactaatgt agacaatttg caatcacaaa ttgtttatgt
    19561 ggagaaaatg gcaccattga ttgctcaatc accatccatc acagctcaac attcgtatat
    19621 taacaagatt gctgatttgt tgccaaactt tgactatttt caagtagaac aatcagtaaa
    19681 tgcattaagg attcaagata ggcaaaagcg tcaaggtcaa atagctcaag ccgtcagcaa
    19741 tcttgtgacc ttaccaatgc caaaaagttt gacagctatt gctaagacag aaagtcatct
    19801 catgcatcgg ctcttacatc atgactattt attaaatgaa tttcgacatc gtgatgattt
    19861 ttattttgat acctctacct tagaattact ttatcaacgg ctgaagcaac aaggacacat
    19921 tacatcttat gatttgtcag agatgtcaga ggaagttaat cgtgcttatt acaatgtttt
    19981 agaagaaaac cttcccaaag aagtagctct tggtgagatt gatgatattt tatccaaacg
    20041 tgccaaactt ttagcagagc gcgatcttca caaacaaggg aaaaaagtta gagaatctag
    20101 taacaaaggc gatcatcaag cggctctaga agtactagaa cattttattg cgcagaaacg
    20161 aaaaatggaa tagaggaaat tatgacaaaa caaaaagaaa taacaacttt taacgttcaa
    20221 gttgcggagt ttattcgcca tcacaaaaaa gaaggaacag cgattgatga tgacgtgacc
    20281 gaaaaacttg tcattccatt tgctttggat gctgatcaaa ttgatgacct ccttgagcgt
    20341 ttgacggatg gtggaatttc tattaccgat aaagaaggca acccatcgtc taaatacatt
    20401 gtggaagaac caaaaccaga agagttaacc gatgaagaac taattggtag caactctgct
    20461 aaagtgaatg accctgtccg catgtacctc aaagaaattg gtgtggtacc gcttttaaca
    20521 agtgaagagg aaaaagaatt ggctgttgcg gttgccaagg gagatttaat ggctaaacaa
    20581 cgtttagcgg aagcaaacct tcgtcttgtt gtctcaattg caaaacgtta tgttggacgt
    20641 ggaatgcaat ttcttgattt aattcaagaa ggtaacatgg gactcatgaa agctgttgat
    20701 aaatttgatt attcaaaagg attcaaattc tcaacttatg caacatggtg gattcgtcaa
    20761 gctataacac gcgcaattgc agatcaagca cgtacgattc gtatccctgt tcatatggtt
    20821 gaaacgatta ataaattagt ccgtgaacaa cgtaaccttc ttcaagaact tggtcaagat
    20881 ccaacgccag aacaaatcgc agaacgtatg gaaatgactc cagacaaggt tcgtgaaatt
    20941 ctaaaaattg ctcaagaacc tgtttcttta gaaacaccaa ttggggaaga agatgatagt
    21001 cacttaggtg attttatcga agatgaagtt attgaaaatc cagtagatta tacgacgcgt
    21061 gttgttcttc gtgagcaatt ggatgaagtt ttagatacgc ttactgaccg tgaagagaac
    21121 gttcttcgcc tacgctttgg ccttgacgat ggtaaaatgc gtacgttaga ggacgtaggt
    21181 aaagttttta acgttactcg tgagcgcatt cgacagattg aagctaaagc ccttagaaaa
    21241 cttcgccatc ctagtcgtag taaacaatta agagacttta tagaggacta aaatcgtcca
    21301 gtggacgatt ttaggtcgtt cctttgaaat aagaaaggag cgaaaatccc aagtggcact
    21361 tatcagcggt acacctacaa attagaaaac ggaccgaatg tggtgggtat ttttaagggt
    21421 agacttgata tcttaaacaa gcccagaggg caatttcctc taaataggca aagctttagt
    21481 ggttttttta cttatctacg acatattcaa aaaatgaaag gaaagccatg tctgatacac
    21541 caaaatatac acaagatcag gtgatagcta tcaagaatag aattcttgaa gctttagaaa
    21601 ctgttattga tcccgagcta ggtattgatg ttgttaatct aggcttgatt tatgaaattc
    21661 ggtttaatga taacggttat acagagattg atatgacact cacaacaatg ggttgtcctt
    21721 tggcagactt gttgacagat tacatccatg atgccctgca agatgtgcca gaagtcacta
    21781 agactgaggt caaattagtc tggtaccctg cttggacggt tgataaaatg agccgctatg
    21841 ctaggattgc gctgggtatt cgctaatcat tgatagtaaa gggatgaaat attccctttt
    21901 ttgatgtaga ataaaaggaa atacaggtga aagcctttgg ttaatgttag agaacactaa
    21961 gatactgaga aaagtgttct acctatggca aaaaggagaa ctgatgattt taattacagg
    22021 aagcaatggt caattaggga cagaacttcg atacttatta gatgaacgag gtgttgatta
    22081 tgtagccgtt gatgtcgcag aaatggacat cacaaatgaa gacaaagtcg aagctgtttt
    22141 tgcgcaggtc aagccaacat tggtctatca ttgtgctgct tatacggcag ttgatgcagc
    22201 agaagacgaa ggaaaagcct tgaatgaggc tattaatgta acaggctcag aaaatattgc
    22261 caaggcttgt ggaaaatatg gggctaccct tgtttacatt tcaacagact acgtatttga
    22321 tggcaataaa ccagtcggtc aagaatgggt agaaacagat cgtccagacc ctaagacaga
    22381 atatggccgt acaaaacgtt taggagaact agctgttgaa cgatacgcag agcattttta
    22441 tattatccgt actgcttggg tatttggaaa ttatggtaaa aactttgtct ttaccatgga
    22501 gcagttagcg gaaaatcact cccgtttgac tgttgtcaat gaccaacacg gtcggccaac
    22561 gtggacaaga accttggcag aattcatgtg ttatttgaca gagaatcaaa aagcctttgg
    22621 ttactatcac ttgtcaaatg atgctaagga agacaccact tggtatgatt ttgccaaaga
    22681 aatcttaaaa gacaaggctg ttgaagtggt gccagttgat tcatcagctt tcccagcaaa
    22741 agccaaacgt cctttaaatt caaccatgaa tcttgataag gcaaaagcga cagggtttgt
    22801 tattccaaca tggcaagaag ccttgaaggc attttaccaa caaggactga aaaagtaagt
    22861 attctaaaaa gagttggctt tctaaggcca actctttttc atgggtttaa ggtcgcattg
    22921 gccttctaat tgtggtataa tatcactgat tatattttag aatggggtag tatgcaatgc
    22981 aggatgtttt tatcattggt agcagagggt taccagcgaa atacggtggc tttgaaacct
    23041 ttgtcgaaga gttgattagt catcaatcat ctaaaaacat tcgttatcac gttgcttgtt
    23101 taagcgatac gaagcataag gttcattttg attataaggg ggcagattgt ttttacctta
    23161 atcccccaaa acttggacct gctagagtta ttgcttatga tatgatggca attacctatg
    23221 ccctgtctta tagcgaccaa caccagattc agaaccctat tttttatgtg ttgggcaata
    23281 ctgtaggtgc ttttattgcg ccatttgtga agcagattca caatcgaggt ggacgctttt
    23341 ttatcaatcc agacgggcta gagtggaaac ggtctaaatg gtcaagacca gtgcaggcct
    23401 acctgaagtt ttccgaaaag caaatgacta gacaggctga tttggtcatt tcagataata
    23461 ttggcattga ccgctacctt aaacaggttt atccttggtc taaaacatgt tttattgctt
    23521 atggaacgca gacacaacct tcacgtttga caacagcaga tagcaaggtc agaacttatt
    23581 ttcaaacttt tgatattagc gaaaaggatt actatctcat tttaggacgc tttgttcctg
    23641 aaaataatta cgaaaccgct attaaagaat ttatggcttc ctcaactaag cgtgatttag
    23701 tgattatctg taatcatgaa ggcaatgctt actttaagca attacttgct gagacagagt
    23761 gtgataaaga cccacgcatt aaatttgttg gtacccttta tgacaaagaa ctattagcct
    23821 acattcgaga acaggcttat gcctatatcc atggtcatga ggtaggaggg actaatccag
    23881 gccttctaga agcactagcc cataccaatc ttaatttggt tttaggagtt gattttaacc
    23941 agtcggtggc taagtctgct gcgctgtatt ggaccaagca aaaagggcaa ttagtagagc
    24001 tgattaacca agttgatgca ggttttgata gtgatcatct gggcaaagaa gccaaagcta
    24061 ttattcaaga acattacact tgggaaaaaa ttgtagggga gtacgaggct ttatttttaa
    24121 atgaacatta atattttact atccacctac aatggagaac gcttcttagc agaacaaatt
    24181 caaagtatcc aaaggcaaac agttaacgac tggaccttat tgattagaga tgatggttca
    24241 actgatggca cccaggatat tattcgcaca tttgtcaagg aagacaaacg aattcagtgg
    24301 atcaatgagg ggcagacaga aaatctggga gttattaaga atttttacac cctcttaagg
    24361 caccaaaaag cagatgtcta ttttttcagt gaccaagatg atatatggtt agacaataaa
    24421 ctggaagtga ccttattgga ggctcaaaaa catgaaatga cagctccttt attggtttat
    24481 acagacctca aagtggtaac ccaacattta gctatttgcc atgacagtat gattaagacc
    24541 caatctggtc atgcaaacac aagcctactt caagaattaa ccgaaaatac cgtaacaggc
    24601 ggcacaatga tgattactca tgctctggct gaggaatgga ccacttgtga cggtttattg
    24661 atgcatgact ggtatttagc tttactagct tctgctactg ggaaattagt ttaccttgat
    24721 attccaacag aattataccg tcagcacgat gctaacgtgt tgggagctag aacttggtct
    24781 aaacgcatga aaaattggtt aaccccccat catttagtca acaaatattg gtggttgatt
    24841 acttcaagcc aaaaacaggc tcaattacta ttagatttac cattaaaacc aaatgaccat
    24901 gaattggtaa cggcctatgt ttctttattg gatatgcctt ttaccaaacg cttagctacc
    24961 ttgaaaaggt acggttttag aaaaaatcgc atctttcaca cctttatttt tcgtagttta
    25021 gttgttacct tatttggtta caggagaaag taagaatgaa ttttttaaca aagaaaaacc
    25081 gtattttact gagagaaatg gtaaaaacgg attttaaatt acgctatcaa ggaagcgcaa
    25141 ttggctatct atggtctatc ttaaaaccgc ttatgatgtt tacgattatg tacttggtat
    25201 ttattcgttt tcttcgcctg ggtggaaatg tacctcattt tccagtagcg cttttattgg
    25261 caaatgtcat ctggtctttt ttttcagaag caactagcat gggaatggta tctattgtat
    25321 ctcggggaga cctgttgcga aaattgaact tttctaagca catcattgtt ttttcggcag
    25381 tgttaggagc tttaattaat tttcttatta atttggttgt tgttttaatt tttgcgttga
    25441 taaatggtgt gactatatca gggtattctt atctctctct ttttcttttt atagaattag
    25501 ttgttttagt gcttggaatt gcattgttat tgtcgaatgt ctttgtttat tatcgtgact
    25561 tagctcaagt ctgggaagta ctattacaag caggtatgta tgccactcca atcatttatc
    25621 cgatcacttt tgttttagat agccaccctt tggcggcaaa gttgttgatg ctaaatccag
    25681 tagcacaaat gattcaagat tttcgttatt tattgattga cagggccaac gtaacgattt
    25741 ggcagatgtc aaccaattgg ttttacattg ttattccata tttagtacca tttgttatat
    25801 tatttattgg catctttgtc tttaagaaaa atgccgatag atttgcggag attatttaat
    25861 gattaataga gaaattgcag taaaagtaca gcatgttagt aaaacattta aactgcctac
    25921 agaagcaact aaaagttttc gcacgactct ggttaatcgc ctaagaggga ttaaaggatt
    25981 tactgaacaa catgtgctaa aagatattaa ctttgatgtt tataaaggcg atttttttgg
    26041 aattgttggg cgtaacggct cgggaaaatc aacgctcctt aaaattattt cccagatcta
    26101 tattccagaa aaaggacagg ttacagtaga tgggaagatg gtttctttta tagagcttgg
    26161 agtgggattc aatccagaat taacaggacg agaaaacgtc tatatgaacg gcgccatgct
    26221 gggatttacc aaagacgaag ttgatgatat gtacaatgat attgttgatt ttgcagagtt
    26281 gcatcatttt atgaatcaaa aattaaaaaa ttattcttct ggcatgcagg tacgtttagc
    26341 attttcagtg gctattaaag cccaaggtga cgttcttatt ttagatgagg tgcttgctgt
    26401 aggagatgaa gcttttcagc gaaaatgtaa tgattatttt atggaaagaa aagacagtgg
    26461 taagacgact attttagtga cacatgatat gggagctgtt aagaagtatt gtaaccgtgc
    26521 agttcttatt gaagatggtc ttgttaaagc atatggagaa ccatttgatg ttgctaatca
    26581 gtatagtgta gataatacag agacagctga ggatgcaatg aatgctgaaa aaatatctgt
    26641 atctgatatt gccaaagatt tgaaagtgtc attaatctca aatccaagaa taacaccaaa
    26701 tgacacaatc acatttgaag tttcttatga agttttaaaa gatgatttta cctacattgc
    26761 cttttcttta acggatattg atagaaacat ttgggtttac aacgacaatt ctttagatta
    26821 tccaacacaa ggtataggga gaaaatgcat ttcctaccaa tgtcagctat ctcaacttaa
    26881 tgatataaaa ctaaaattag aagtaactgt ccgagataag aacggtcaga tgctactctt
    26941 ttcaacagca gaacaatcac cccagatagt gattcaaaga aacgatattg atcaagatga
    27001 tctgtcagct ctagattcag caagtggctt gtatcaacgt aatgggaagt gggtttttca
    27061 ttaatgagta atagctagaa gggaatttat gtataaagtt tcaattattt gcaccaatta
    27121 taacaaagct ccttggatat ctgatgcact tgacagtttt ttaagccaag tgacagattt
    27181 tgaggttgaa attattgtta ttgatgatgc ttctacagat gactcacgag agattttaaa
    27241 gagttatcaa aaaaagtctt caggaaaaat taaattactc tttaacgaaa ctaatattgg
    27301 aataacaaag acttggataa aagcatgcct ttatgcaaaa ggcaaatata ttgctagatg
    27361 tgatggtgat gattactgga cggatagttt taaactccaa aaacaagttg atgtcttaga
    27421 agcttccaaa cggtcacgat ggtgtaatac tgattttgac tttgtaaata gtcaaggcga
    27481 cttattatat gctaatgctt tttcatctgg tcatacacct ttgacagata cttacgaaaa
    27541 agttttagcc ttaaaaggga tgacgatggc atcgacatgg ttagttgatg ctgatttaat
    27601 gagacaagta aaccaaaaaa tcaatgtaga tacaccagac gatacttttg atattcaact
    27661 agagttattt caattgactc aactgaccta tattaaagac tcaacgacgg tttatcgcat
    27721 gacaaccgat tctgattcaa gacctactga tacaccaaaa atgattcatc gtattcaaaa
    27781 actacttgat actcagttaa attacttaaa aaagtataat caggtagata caaaagaagt
    27841 gtctaaacta ttattacaac aagatgctaa gcaagaaata cgaattcatg agttgagttg
    27901 ctttattcaa gaattacaac aaactatcgt agataaaaca aagcagcaag aaacacgtga
    27961 agtggagttg caaaatgtca tagaagaaca aaaaaatcaa ctatctgaat taagacaaca
    28021 ataccatgcc attattaatt cacgtcaatg gaaatacacg tctaagctca ttgcttttat
    28081 taggagaaaa aaatgaatcg tattttatta tatgttcact tcaacaaata caataaaata
    28141 agtgcacatg tttactatca attggaacaa atgagatcac tgttttctaa gattgttttt
    28201 atctcaaata gtaaagtgag tcacgaagat ttaaaacgtc tcaaaaacca ctgtcttatt
    28261 gatgagtttt tgcaacgcaa aaataaaggt tttgattttt ctgcatggca cgatggcttg
    28321 attactatgg gatttgacaa attggaagag tttgactcat tgacgattat gaacgatact
    28381 tgttttggtc ctatttggga gatggctcct tattttgaaa attttgaaga aaaagaggca
    28441 gttgactttt ggggaattac taataataga ggtacaaaag cttttaaaga acatgtccaa
    28501 agttatttta tgacgtttaa aaatcaagtc attcaaaaca aagtttttca acaattttgg
    28561 caatcgataa tagaatatga aaacgttcaa gaagtgattc aacattatga aacgcaatta
    28621 acatccattc tcttaaatga aggctttagt tatcagacgg tctttgatac tagaaaagct
    28681 gagtcgtcat tcatgccaca tccggatttt tcatattata atccaacagc aattttaaaa
    28741 caccatgtgc cttttataaa agtaaaagct attgatgcta accagcatat cgctccttac
    28801 ttattgaatc tgatacgaga aacaaccaat tatcctatag atcttattgt ttcacatatg
    28861 tcgcaaatct ctttgccaga tgctaagtac cttttatctc aaaaatacct aaactgccaa
    28921 cggttagcaa aacaaacttg tcaaaaggta gctgttcatt tacatgtttt ttacgttgat
    28981 ttgctagatg aatttttaac agctttcgaa gactggaact tccattatga tctttttatt
    29041 acaacagata gtgatatcaa aagaaaagag atcaaagaaa tacttcaaag aaaaggtaaa
    29101 actgctgata tacgcgttac gggaaataga ggaagagata tttatccaat gttattacta
    29161 aaagataaac tttctcaata tgattatatt ggtcatttcc atacgaaaaa atcaaaagaa
    29221 gctgattttt gggcaggaga atcttggcga aaagaattga ttgatatgct cgtgaaacca
    29281 gcagatagta ttcttagcgc ttttgagaca aatgatattg gtattataat cgcagatatt
    29341 ccaagttttt ttagatttaa taagattgtc aatgcttgga atgagcattt aatcgctcaa
    29401 gaaatgatgt ctttgtggag aaaaatggat gttaaaaaac aaattgattt tcaagctatg
    29461 gatacatttg ttatgagtta tggaacattt gtatggttta aatacgatgc tctaaaatca
    29521 ctttttgatt tagaattaac tcaaaatgat attccaagtg aacctttacc acaaaactct
    29581 atattacatg cgattgagcg gttacttgtc tatatagcgt gggggaattc ttatgatttt
    29641 aggattgtta aaaatcccta tgagttaaca ccttttattg acaataaact gttaaattta
    29701 cgtgaagatg aaggagctca tacctacgtt aactttaatc aaatgggcgg tatcaaagga
    29761 gcattaaaat atattattgt tggtcccgct aaagcaatga agtatatatt cttgcgttta
    29821 atggagaaac ttaaatgatt aaagacacat ttttaaaaac caattggtta aatattagac
    29881 accatattat ccttcttgtt ttcagttttt atttcagttt ttacagtttg gcgaaagaac
    29941 tagtaagctc cacggcacaa ccggtaaact attatactca tttactaaat gtttcttttg
    30001 tgggatatat tatatcactg attggattat cttattattt gagtcgccaa gttagtcgac
    30061 agttgttttt gaaaactagt tttattgtga tatcttatct aattgtcagc tattgggtac
    30121 aaataacaca gcacctgaat gataaacggt ttgatatctg gtcattaact aaaaatcaat
    30181 tttatcaatt tcaagctcta ccttctttac tcattatttt agtgatggcc actttaataa
    30241 aaatattggt agcatatttt gcaatagaaa aagatagatt tgggctatta ggctatcaag
    30301 gtaatacttt ttctgtagct ctgattttag cagttgtgcc aattaatgac atacatctgt
    30361 taaaactaat aagttctcga ttttctgaat tagtaacagc aggtaatagc caaattgcac
    30421 tgttaaaaat aagtggactg ttgatagttt tacttgtcat atttgcaaca atcatatacg
    30481 tggttttaaa tgctctaaaa caccttaagt caaataaatc ttcattttca gtagcagcta
    30541 ctactagttt gtttttagca ttagttttta actatacgtt ccagtatgga gtaaaaggtg
    30601 atgaagcatt gctaggatat tatgttttcc ctggagctac tctttttcag atagtagcta
    30661 ttacactagt tgctctttta gcatacgtga taacgaatag atattggcca actaccttct
    30721 ttttgcttat tctgggaaca attatttctg ttgttaatga tttaaaagaa tcaatgagaa
    30781 gcgagccgtt attagtaact gattttgttt ggttacaaga attaggttta gtgacaagct
    30841 ttgttaaaaa atcggtgatt gtagaaatgg ttgtaggact tgctatttgt attgtggtgg
    30901 cttggtatct acatggccga gttttagcag ggaaattatt tatgagccct gtcaaacggg
    30961 caagtgctgt attaggttta tttattgtat cttgtagtat gttaatacca ttttcttatg
    31021 aaaaagaagg taaaatatta tctggtcttc cgattatttc ggctttaaat aatgataatg
    31081 atataaactg gttaggtttt tcaacaaatg ctaggtacaa atctttagca tatgtttgga
    31141 caagacaggt gaccaagaaa ataatggaaa aaccgacaaa ttatagccaa gaaacaatag
    31201 cgagtatcgc tcagaagtac caaaaattag cagaagatat taataaagac agaaaaaata
    31261 atattgctga ccaaacggtt atttatcttt taagtgaaag tttgtcagat cctgatagag
    31321 tatcaaatgt tactgttagc catgatgttt tacctaatat caaggcaatc aaaaatagca
    31381 caactgcggg actcatgcag tcagactcct acgggggtgg aacggctaac atggagtttc
    31441 aaacgttaac aagcgtacct ttttataatt tttcttcttc agtatctgtc ctttattcag
    31501 aagtctttcc taaaatggcc aaacctcata cgattagtga gttttaccaa ggaaaaaatc
    31561 gtattgcgat gcatcctgct agtgctaaca attttaatag aaaaacagtt tatagtaatt
    31621 taggtttttc caaattctta gctctatcgg gttctaagga taagtttaag aacattgaaa
    31681 atgtcggttt attgactagc gataaaactg tctataataa tattttatct ttaattaatc
    31741 ctagtgaaag ccaatttttc tcagttatta caatgcaaaa tcatattcct tggtcatccg
    31801 attatcctga agaaattgtt gctgaaggaa aaaatttcac ggaagaagaa aatcacaacc
    31861 taacaagtta tgctcggtta ttatcgttta ctgataagga aacaagagca tttttagaaa
    31921 aattaacaca aattaacaag cctatcacag tggtgtttta cggagatcat ttacccggtt
    31981 tatatcctga tagtgctttt aacaagcata ttgaaaataa ataccttact gattatttta
    32041 tttggagtaa tggtactaac gagaaaaaaa atcatccgct tatcaactca agtgatttta
    32101 ctgcagcttt atttgagcat actgattcaa aagtatcacc ttactatgct ttgttaacag
    32161 aggtactgaa taaagctagt gtcgataaat caccagatag tcctgaagtt aaagctattc
    32221 agaatgattt aaaaaatatc caatacgatg tgactatagg aaaaggttac cttttgaaac
    32281 acaaaacttt ttttaagata tcacgttaag aaaaatgcta ggctgtccga gtataggcaa
    32341 gcatcaaggt ttggtaattt gctcaaatga ttgtcaacag agtgtctagg accaggttta
    32401 aaagattata attcttaagg tcttattcgt ttataaaaaa tgaatactat tttaaaatct
    32461 taattgaaat gaataggaga agttttcgtg aaaaagttaa tcattattcc tgcttacaat
    32521 gaaagcagta atattgtcaa tactatacgt actattgaat cagatgcccc ggattttgac
    32581 tatatcatta ttgatgattg ctcaacggat aatacgttag caatatgtca aaaacagggg
    32641 ttcaatgtta tttctttgcc cattaacctg ggaattggcg gtgcggtgca aactggctat
    32701 cgttatgcac aaagatgtgg atatgacgtt gcagttcaag tagatggaga tggtcagcac
    32761 aatccatgtt atttggaaaa aatggttgag gtattagttc aatcttcagt aaatatggta
    32821 attggatcac gatttatcac aaaagaaggg tttcagtcat catttgctcg acgtatcggc
    32881 ataaagtatt ttacttggct tattgcgcta ctaacaggaa aaaaaataac agatgcaacg
    32941 tcaggtctaa ggttaattga ccgttcattg attgaacgtt ttgctaatca ttatccagat
    33001 gattatcctg aacctgaaac agttgttgat gtattggtta gtcattttaa agtgaaagaa
    33061 attcctgttg taatgaatga gcgacaaggc ggtgtgtcat ctatctcgtt gacgaaatcg
    33121 gtctattata tgattaaagt gactttagct attttagttg ttagattgaa aggaaatcgt
    33181 taaaatgacg gtaacagcca gtttatttat aagttttatt gtattaacct ttgttttctt
    33241 tttgattaac ttaatcaaaa aagacaaact agcgattaag tactctttat tgtggtttat
    33301 tttagcttta ttaattttac tatttacgtg gttacctaac atattaaata aaatgtctca
    33361 cttcctgggt attcattcac caaccaatat gttattcttt ttaggttttt gtttgagttt
    33421 agctattatt ttttcactga ctaataatat ttcacttcaa aatgataaag taaaacgtct
    33481 gacccaagag gtggccctta tgaaaaaaga gaaaaccaat gattaatcct tcaaaacaaa
    33541 accaaacgat ttttttatgg aatatgttag gaagtttatc aacagctgta atatcagtta
    33601 tattacttat ggtggttact aggttactaa cttcggctga ttcagatatt tacgcctttg
    33661 cctattcttt tgctaatatg atggtagttg ttggactttt tcaggttcgt aattatcaag
    33721 caacagatat taatgaaaaa tattccttta gtcagtactt agtggcaaga ctgatgactt
    33781 gtttattaat gttagccata acagtaattt atttaacgtt aactaagaca gatagctaca
    33841 agagtacaat tgtctttcta gtctgtttct atagatcgac agatgctttt tcggatttat
    33901 atcagggaat gttccaacaa catgaacggc tggatattgc aggtaaatcg ctagcctaca
    33961 gaaatactct tatttttatg gtgtacacag caataatatt atattccaaa aatcttactt
    34021 tagcattagt agctgtctgt atagtttcat tagtttttat aatgtattat gacattggtc
    34081 attcgaaaaa atttcaaaag ttgatgttta gtgaattatt aagtaatatt tcatttcaaa
    34141 acagtttaaa gttattaaaa gaaagttttc cactttttct aaacggtttt ttgattatct
    34201 atatttatac tcaaccaaaa tacgctattg aactaatgac gactttaggt gaagttgctt
    34261 tgggctctca aacaattttt aatattttat ttatgccagc ctttgttatg aatttgctaa
    34321 ttttattttt tagacctcat attacacaga tggctattgc tttaatcaga ggtcaaataa
    34381 aagagtttaa taagatacaa gttcaattgt ttgcttattt aggagttttt tcactgatag
    34441 tgttagttgg aagtggtttg tttggtattc cctttttatc aatactatat ggtactaacc
    34501 ttacggatta ttgggtagat tttatgttga ttatgctagg aggctcgatt ggtagttttg
    34561 cgacagttat cgataatatc ttaaccgcta tgagaaaaca gcaacttctt cttattccat
    34621 atacaggagg atttttgatt tcgttattaa ttaccaatct ttttgttatg aaatatcaca
    34681 ttttaggagc tgctttgagc tttttaataa caatgttggt ttggttggga ttatccatta
    34741 tgatttatct atttattatg aatagattta agaaggggag agttaatgca acaatctatg
    34801 actaaagtta aatatctttg gaaagaaaat aataactata tttattcgac ttttttgaca
    34861 ttatttctga cagttatttt atatgccaat agtttaaatc tacctttaaa atttattagt
    34921 cttctttttg tggtgagcac tttactgata gtgtttttac caaaaaagtt agaggttgct
    34981 acgatcattt ttattttagc atttggaacg atatctgcta tcatatcacc tataaatgat
    35041 attcctgatg aatatgttca ttattcaagg acagtttata tctcagaagg tgatattaat
    35101 cttaccaaca ataacaaaaa gttaagaata tccaaagatg ttgataagct tattaaacag
    35161 tcaggaaaaa catttataac atcaaacttg aaagcaacta aacacagcac aagagagtat
    35221 agctatcctt acatcaaagg aactaatgca tattatagtt tttcttatat accacaagct
    35281 ttgggtattt tagtaggaaa tgcgctggat ttacctatac ttttaacata ttatttcgga
    35341 agattgtgca accttattag ctacgctatg cttgctttta tagctatcaa gttgtctggt
    35401 tcttttaaac aagtgatagc tgttgttact ttactaccta tgaacattta tttagcagca
    35461 tcttttaatc aagacggctt tgctatcggt ttagttttag taacaattgg attgtttatt
    35521 aacttgctct catcaaaaga taaatctaac tataatacca aattcttcct ttatttagtt
    35581 ctatgtgggt tactagttct ttcaaaattc acatactttt tattagtatg ccttccatta
    35641 tttattccta atgaaaaatt cggaaaaaat accaagttag tcatcttgaa aaaattggga
    35701 ggactattac tcatttttct ttttgctgca atgtggttta gactttatgg acaggttaaa
    35761 accccatatg tcgcggattt tctaaaagaa gtaaacgtta gccagcaagt taaaaatatg
    35821 ctagaatccc ctatagtcta tagcagtatt attattagac atatggtaat taatctgatt
    35881 aatatgaata atatttttca gtttggcgca ttaagctatg gtataacgaa cctattcccg
    35941 ctttatgtgt gtttcttctt ttttgtttat attagtaatg ctagtaaaat aactattaat
    36001 attgtagaaa aaatgggtat aatctttgtt atttcagcga ttataggtgc aactgtatta
    36061 gctatgtacc tgacttggac accagtaggg tcctcaactg tcttaggtgt tcaaagtcgt
    36121 tatctgatag gaattatccc attagtgttg cttcttttta gtagtcaaca gcaaaagttc
    36181 aaacaaatag aggatatcct ttctgacaaa ctggctattc atgtttcgct tttgtttatt
    36241 ctcgcaatgt taatgagtac tatttttaga tattatcatt aaacgcttaa ttagaggctt
    36301 taaaaaactt agcttgaata agtattttaa agccttttat gctataatta aattgagaaa
    36361 ttattgaggt ggcctatgaa gtacgataac ttgttagatc gatttataaa atatgtcaaa
    36421 gtgaatacaa gaagcgatcc agacagtgag actactccta gtacggagag tcaagaagca
    36481 tttgccttaa cgattttaaa gcctgaaatg gaggcaattg gtttgcaaga tgttcattat
    36541 aatccagtta atggctatct tattggaact ctgcctgcca ataatccaac cttgacgcgt
    36601 aaaattggtt ttatagccca tatggatacg gctgatttca atgctgaaaa tgttaatccg
    36661 cagattattg acaattatca aggagaggac attacacttg gcagttctaa ttataagctg
    36721 gatccaaaag catttccaaa tcttaataat tatatcggtc aaacattgat taccactgat
    36781 gggactacac ttttaggggc agatgataaa tctggtattg ctgaaatcat gacagcaata
    36841 gaattcttaa catcacaacc acaaatagag cactgtgaca ttaaagtggc ttttggccct
    36901 gatgaagaga ttggggtcgg agctgataag tttgaggtgg ctgattttga ggtggatttt
    36961 gcttatacta tggatggcgg tcctttaggc gaattgcaat atgaaacttt cagcgctgca
    37021 gctctagaag tgactttttt aggcagaaat gttcatcctg gtacggctaa ggatcaaatg
    37081 attaatgccc ttcagttagc aatagatttt catgagaagc tacctgctaa agagcggcct
    37141 gaatacacag atggttatca aggcttctat cacttaacgg gactaactgg aacagttgaa
    37201 gaggcacggg catcttacat tattcgtgat tttgaagaag catcatttga agctagaaaa
    37261 gtgaaagttg aaaatatagc tcaatcgatg aatgctcagc taggaacaaa acgtgtcttg
    37321 gtagagctta atgaccaata ctacaatatg aaaaaagtta tcgaaaaaga tatgaccgct
    37381 attgagttag ctaaagaagt aatggaagag cttactatca agcctgtaat cgaacccata
    37441 cgtggaggaa cagatggctc taaaatttca tttatgggta ttcccactcc taatattttt
    37501 gcagggggtg agaatatgca cgggcgtttt gagtttgtta gcttacaaac gatggagaga
    37561 gctgtcgatg tcattattgg acttgtttgc aaagcctaat tatcatgtaa ttgatattta
    37621 gtggaagggg cttataaaaa tgattaaact atttggtaaa ataaggtatc actggcagcc
    37681 agagttgtct tggtctatta tttattggtc tattgcgttt gcacctattt ttgtaggttt
    37741 atctttgttg tatgagcgca ctgaaatacc tagtcgggtt tttattctat ttgctatttt
    37801 tgctgtccta gttggcattg gattacatcg ttatttcatt attgaaaata atggtatttt
    37861 aagaatcgta tcttttaaat tgtttggtcc acgtaagcta cttatttcca ctattactaa
    37921 gattgaggtg accaaatcaa cactttgtct gcacgttgaa gataaaagtt atctctttta
    37981 tatgcgcaaa tggcctaaaa aatattttct tgatgcctta gcggttaatc catacttcca
    38041 aggagaagtt atattaagtg ataactttat taaattagac tattttgaag tttatcagca
    38101 tgataaaaaa gcccttactc gagggtaaga gctttagttg ggcaagattt gacagctaaa
    38161 atagcgtcct tatctgaagg acaaattgac tgacttgttt cagatgagct tgaaaatgtg
    38221 acgataccat tgtcatgata atcaaaaagt gatgaatagg tttggcatag accacaagcg
    38281 atgcattttt ctggaatgat agatactttc ataactatta ttctaatatg attttgttaa
    38341 attaacaagg ggggacgatc atggctaaag aaccatggga agaaaaaatt gttgatgata
    38401 ctatagggac acgaacacgt aaatcaagaa atgctttcat tagcacgcct tggttgactg
    38461 ctttattaag tgtattcttt gtcatcattg ttgctatact ttttattttc ttctatacat
    38521 caaatagcgg tagtaataga caagctgaaa caaatggttt ttatggagca tccactcata
    38581 aaaaaacaag gaaagcttct aacgctaaaa aaacatcaag tagttcaaca actacagaca
    38641 caacaccttc tagcgaagaa acacttgctt ctagtgaagg aaccggcgaa acccttactg
    38701 tattggcagg tgagggggca gcttctattg cagctcgtgc aggtatttct gtggagcagt
    38761 tacaagcact taatccagag cacatgactc aaggatattg gtatgccaat ccaggagatc
    38821 aagtcactat taaataattg aagaggaaaa aatgaaagca attaaaattg cgattgatgg
    38881 gccagcttca agtggaaaaa gtacagtagc caagattatt gcaaaaaatc ttggctatac
    38941 ttatctagat actggtgcta tgtatcgctc agcaacttat atcgcactga cacatggcta
    39001 tacggataaa gaagtagccc ttattttaga ggaacttgag aaaaatccta tttcctttaa
    39061 aaaagcaaaa gatggctccc aattagtttt tcttggggat gaggacgtga ccttagtcat
    39121 taggcaaaat gatgtgacta acaatgtttc ttgggtctca gctttgccag aaattagaga
    39181 agagctggtt catcaacaaa gacgcattgc acaagctggt ggcattatca tggatggtcg
    39241 tgacattgga acggttgttc tcccagatgc ggaactaaaa atctttttag tggcttctgt
    39301 cgaagagcgg gcagagcgcc gctataaaga aaacctagaa aaaggaattg aatcagattt
    39361 tgagacgcta aaagaagaga ttgcagctcg tgattacaag gatagtcatc gtaaggtttc
    39421 acctctaaaa gcagctgaag atgcccttat ttttgatacc acaggtgttt ctattgatgg
    39481 cgtggtgcaa tttatccaag aaaaagcaga aaaaatagtt gacatgtcct agagcctatg
    39541 ttagaatagt aacaatgaga aaagtagaag tgagagcttc tcgccttgcg acttaggttg
    39601 tctggtccta acatgtcaaa ttcctatgga atattatgtg tgcgggcttg atttatcaag
    39661 tccgctttcg tttttctcta aaaaaataaa gaggtgaaga tcatagctaa aaaggatcta
    39721 ttcattaatg atgaaattcg cgttcgcgaa gttcgtctcg ttggtcttga aggtgaacaa
    39781 ttaggtatta aaccattgtc tgaagcgcaa tcattggctg atgcttcaaa tgttgatttg
    39841 gttttaatcc agccacaagc tgttcctcct gttgccaaac ttatggacta tggaaagttc
    39901 aaatttgagt atcaaaagaa acagaaagaa caacgtaaaa aacaaagcgt tgtgactgtg
    39961 aaagaagttc gtctcagtcc agttatcgat aaaggtgact ttgaaacaaa acttcgtaac
    40021 ggtcgtaaat tccttgaaaa aggaaataaa gttaaggttt ctattcgttt caaaggacgt
    40081 atgattactc ataaagagat tggtgccaag gtactagctg actttgctga agcgactcaa
    40141 gatattgcta tcattgagca acgagcaaaa atggatggac gccaaatgtt tatgcaactt
    40201 gcaccaattt cagacaagaa gtaattgtca cagtttcatt atatctttaa gaggagaata
    40261 ctaaaatgcc aaaacaaaaa acacaccgcg catcagctaa acgttttaaa cgtacaggtt
    40321 caggcggttt gaaacgcttc cgcgccttta catcacaccg tttccacgga aaaactaaaa
    40381 aacaacgtcg tcatcttcgt aaagctggtt tggttagctc aggagatttc aaacgtatca
    40441 aagcaatggt tactggtctt taattttaaa ggcagtagac atttacgagt attataagaa
    40501 ttatttgaag gagaactatt aatggcacgt gttaaaggtg gcgttgtttc acgcaaacgt
    40561 cgtaaacgta ttttaaaatt agctaaaggt tactatggag caaaacacat cttgttccgt
    40621 actgcaaaag agcaagtgat gaactcttac tactatgcat accgtgaccg ccgtcagaaa
    40681 aaacgtgatt tccgtaaact atggatcact cgtatcaacg cggctgctcg tatgaacggt
    40741 ttatcatact cacaattgat gcacggtttg aaacttgctg aaatcgaagt aaaccgtaaa
    40801 atgcttgctg atttagcagt agctgatgca gcagctttca cagctcttgc tgatgcagcc
    40861 aaagcaaaac ttggcaaata ataaacgcta tacctaaaaa ataactttct attacctata
    40921 gaaagttata aagaaacaaa aatgaaggag acgatggacg tcttcttttt attatactca
    40981 atataataaa aagtagtttc tcatgtttta ttaccagtaa tgtgggatat ttagatggta
    41041 gcaagaagtt ttatagctga tttgttttct ttaggtctaa ttagcatatt ttgattactg
    41101 ataaacttga atatcgccaa taaaaaagaa gcaaaattat tattttgctt ctagtcagat
    41161 cattaaattg attattctct atttttggtg ttatcctctt ttagttcaga agttgccgcg
    41221 tcagcttcta cgggatttag ttctaagtaa gatggtgctt taaaaagttt ctgagttgat
    41281 ttatgaccat ttttactgta taaacttgtt gactctgatc cgagttttgc tgaaatatct
    41341 ttcagttgtt ttaactgctt agtgtagata aactggttag gatcaatagc ttttagacca
    41401 ttttgagtat caaagcgcag gagatcaccc gtttgaatag cgtcgctagc tgctagttgt
    41461 tgagcaacag cagagcgaat ttccttagtt ttggctatag tcatttcatc gggattagtg
    41521 atttctaaac ctgtttgcgt gttgtacaga cgtccactat agttagtgta ttcaggagtc
    41581 atataagtcc cagatgttcg ttgtgccaca atctggctat tttgaggtga taataaatct
    41641 tgtcctaatt gaacaaactg actagtgtca ataccaagta tgtggagtaa agtaggaaga
    41701 gcatcgattt caccgccaaa ggtttctttg atactaccat tcgtataacc tggaatatgg
    41761 atcatatacg ggactcgttg tagcatagca ttatcatatt cagaccaagt ttcagaatct
    41821 ttaccaagaa gtggagcaag actagaatta cgagaatttg aaataccata atggtcacca
    41881 tataaaacaa aaatagaatt ctcgtacaaa ccagtggctt tcaagtaatc aaaaaaagat
    41941 ttaagggcag cgtctaaata attggcagta gcaaagtaac cattgatcgt ttcatcgtct
    42001 gttttggcta aaggaaaacc ttcttcacta ctttcgcctt ttagactagt ataaggatag
    42061 tgattactca cagtgataaa cttggtataa aaaggttgtt gcatctgttc aagatatttt
    42121 atggaatcct taaacatgta cttatcattt aacccatatt gaaaagagtt cttactattt
    42181 tgtttagaga agtagctaga atcaaaaaaa taattatagc cccattgttt ataagcatta
    42241 ttgcgattcc agaaagttcc aacgttacca tgaaagacag cgctggtata gccacctttt
    42301 tgggctaaaa tacttggagt agcaaactgt gtattttcac caccgtagtt caccataaaa
    42361 gaaccactat ttaaaccaaa taaggaattc tccatcatgg tttcagcatc agaagtttta
    42421 cctgctttaa cctgatgaaa aaagttaggg aatgctaagg tagcatttga gtgataaagc
    42481 gagttgataa aaggcgttac ctcatattct ttatctcctt cttttagttt ataatctatt
    42541 aagaattgtt gaaagctttc taaatgaaga acaataatat ttttgccttt tccaattcca
    42601 aaatactgag gatcaggtgc tgcataatgt cctttgacat aagttttaac atcaattaat
    42661 tcttctgcag tagctccatt tcgttctttt tgagcttgat aggtttgatt gccgctatag
    42721 agggtaaacg ctggtaatcc taaagctctc acaatataag tatttgaaaa gccacgtgtt
    42781 aatagttcag gacgatcaat ttctgctaaa aaaagattaa tagaaagcaa tagactagat
    42841 aaagcggtga tggcaaatgc tgcgcgcttg ttaaaaggac gttgatcatt tttgattttt
    42901 ttagtgatag ataaactaat tagaataata aaatcaagaa tatagataat atcccagatg
    42961 cgtaaaaggt ttaaagcaga gtcccctaat ccagcggaga ctttactact agctagcatg
    43021 gcactcactg taataaagtc tgaaaattct cggtaatata tagaatttga tatcaagaga
    43081 atgttaagga taatataaac cacccaagaa cagatataaa aggctcgggt attcttaacg
    43141 taaagagcaa cccccaaaag taaaaaagct agtgggattg gattgataat agttagaaag
    43201 acttggtata tatttcccaa atctagtgaa aagtctgtat gatatgccca cagggtcttt
    43261 atccagtaac aaaagagtag agtaattata aaacccaatc ttgtgttgat aaaacctgtg
    43321 ataagtgttt taaatttctt cacagtagca acttccttat cgttttttcc taaagatgtc
    43381 atctccaaat aaaatctcag attaaattat accaaaaatg tgaagctaat gcttgttgta
    43441 agttcaaatt tagtaggatt ttttatcaga ttttgttata ataaaaacta tgaataaact
    43501 ctatattgat tcttttgtcg aaaagaagct gacagcaggg gtacaattat tagatgaaaa
    43561 agatttttct aatataaagg aaaaaaatca gttggttcaa ctggtgacca agtccaatcg
    43621 tcccattgga acagcatata tctctaagca aaataaagga attggttggt atctaggacc
    43681 agaaaaaatc gacttgtcta tctcttattt tgttagtcta ttttcagttg ctaaggccaa
    43741 aagacaagat tttgctcaat cggacgagac caatgcttat cgccttttta atcaagaagg
    43801 agacggtttt ggtggagtaa caattgatct ttataaagat tttgcagtct tttcatggta
    43861 caatgccttt gtctatgaca aaaaagaaat gattatggag gcttttcaac aggtttttcc
    43921 tgaagtcaaa ggagcttatg aaaagtgtcg ctttaaaggt ccagatactg aaactgctca
    43981 tctgtatggt gagctggcac aagaaacctt ttcgatttta gaaaatggca tagcctatca
    44041 agtcttcttg aatgagggct taatgacagg tatttttcta gaccagcatg atgttagaag
    44101 agcactagta gatggtttag ctatgggcaa gtcccttctt aacctatttt cctatacagc
    44161 tgccttttct gtagcagctg ctatgggtgg tgctatcgag accacttctg tggacttggc
    44221 taaacgatcg agagaattat cactagctca ttttgagcat aaccagttaa acttagcctc
    44281 acatcatttt gtggtgatgg atgtttttga atacttcaaa tatgccaaac ggaaaaaatt
    44341 aatctttaat gtgattgtga ttgacccacc aagctttgct agaaataaaa aacaaacttt
    44401 ctctgtgagc agggactacc acaaattaat cacagaggcc ttggacatat tgagtcctaa
    44461 gggaactatt atagcttcaa caaatgctgc taatatgact gttagccagt tcaaaaagca
    44521 aattatcaaa ggatttggaa gtcgtcgtcc tgagtctatg actctccagc agcttccgag
    44581 tgactttact atcaataaag cagatgaaag aagtaactat ttaaaggtat ttactataaa
    44641 ggtacgagaa tgagaattgt agcaccagtc atgccaagac attttgacga ggctcaagcc
    44701 attgatattt ctaaatatga agatgttaat ttaattgaat ggcgagcaga ctttcttccc
    44761 aaggatgaga ttgtcgcagt agcaccagct atttttgaaa aatttgccgg aaaagaaatt
    44821 atctttaccc ttcggaccgt tcaagaaggg gggaatatta ccctttcaag tcaggagtat
    44881 gttgatatta tcaaagaaat caatgctatt tataatccag actatattga ctttgagtat
    44941 tttacgcaca agtcagtatt tcaagaaatg cttgattttc caaatcttat tttgtcttat
    45001 cacaactttg aagagactcc tgaaaattta atggaagctt tttcagaaat gaccaagttg
    45061 gcaccgcgtg tggttaaaat tgctgtgatg ccccagagtg aacaagatgt tctagatttg
    45121 atgaactata ccagaggctt taagacgctc aatcctgagc aagaatttgc aactatatct
    45181 atggggaaat taggaagatt gtctcgtttt gcgggagatg tcattggctc ttcctggaca
    45241 tacgtttcat tagatcatgt tagcggtcca ggtcaagtga ctctcaatga tatgaaacgt
    45301 attattgagg tcttagaaat ggatatctct aactagtgaa tggtctaaaa atattatttc
    45361 tacaatagtt aagaaatgat gtttttagat taatgttttt aaaataagtg gaaccaaaaa
    45421 ggagaaaaat tgcgttattt aacagcagga gaatctcatg ggctatcctt aacagctatt
    45481 attgaaggta taccagcagg attaactctt catccagcgg atattgatca cgaattacag
    45541 cgacgtcaag gaggttatgg ccgtggtgcc agaatgtcta ttgagactga tcgggttcaa
    45601 atatcctcag gagttcgtca tggcaaaaca acaggggccc ccattacctt aacggtaatt
    45661 aataaggacc accaaaaatg gctagatgtc atggctgtag gagacattga agagactctc
    45721 aagttaaagc gtcgtgttaa gcatcctaga ccaggacatg cggatttggt aggaggtatt
    45781 aaatatcatt ttaacgattt aagagatgcc ttagagcgtt cctcggctag agaaacaacg
    45841 atgagagtgg ctgtaggcgc tgttgctaaa cgtatcttag ctgaacttgg aattgatatg
    45901 ttacatcata tcttaatatt tggtggtata acgatcacaa taccttctaa gctctctttt
    45961 agagagctgc aagaaagggc tctccattca gaattatcta ttgttaatcc aaagcaagaa
    46021 gaagaaatta aaacgtatat tgataagata aaaaaagaag gggataccat tggtggtatt
    46081 atcgaaacga tagttcaagg ggtgccagca ggtcttggat cttatgtcca atgggataaa
    46141 aaattagatg ccaagctggc tcaagcagtt ctttccatta atgcttttaa aggggtggaa
    46201 tttggagttg ggtttgatat gggattccaa aagggctctc aggtaatgga tgaaatcacc
    46261 tggacaccta cccaaggcta tggtcgtcaa acgaaccact taggtggctt tgaaggtggc
    46321 atgaccacag gacaacctct tgttgttaaa ggggttatga agcccattcc tactttgtat
    46381 aaaccactca tgtcggtaga tattgatagt catgaacctt ataaagcaac ggtggaacgc
    46441 tctgatccga cggccttacc agctgcaggg gttatcatgg aaaatgtggt ggcgacggtg
    46501 cttgccaaag agattttaga gactttttct tctactacca tgtctgaatt gcaaaaagct
    46561 ttttcggact atcgtgctta cgtcaagcaa ttttagatag cgagatactg gcttttatgg
    46621 tatcatacag gtattaatga acaaaaggag actgtcatgt cacaagaaat ttatgactat
    46681 gctaatcaac ttgaaagagc agttcgtgct ctgccagaat accaaaaagt gttagaagta
    46741 aaagaggcca ttcaagcaga cgctagtgct agccaactgt ttgatgagtt tgtcgctatg
    46801 caagaaaaaa tccaagggat gatgcaatca ggccaaatgc caacggctga agaacaaaca
    46861 agcattcaag aacttagcca aaagattgaa gctaatgacc agctaaaagc ttattttgaa
    46921 gcgcagcagg ccttatctgt ttacatgagt gatattgagc gtattgtatt tgctccgttg
    46981 aaagatttag tcaagtaagc caattaagat aggaaaaaaa cagattgctg gcagctcgtc
    47041 aggatctgtt ttttagtgtt tattttcttt gtatcagaaa gttgagcctc tttcttattt
    47101 gtgatatagt caaataaagt gaccaaaata gcaggccagt agtggcttta atgaaggcaa
    47161 gttgtctgct aactggctat gctaaaacat cagtattaga aagtaaaagg tgataaaaat
    47221 ggttattcct tatgattata ttgttattgg tggagggagt gcaggtattg cttctgcgaa
    47281 cagggcagcc atgcatgggg ccaaagtatt gttagctgaa ggtaaagaga ttgggggaac
    47341 ctgtgttaac ctaggctgcg ttcctaaaaa agtcatgtgg tatggcgctc aagtagcaga
    47401 tattttaggg acttacgcta aggattatgg atttgacttt aaagagaaag catttgattt
    47461 taaacaattg aaagcaaatc gtcaagctta tattgatcgg attcatgctt cttatgagcg
    47521 aggctttgag cagaatggtg ttgaccgtat ttatgattat gctgttttca aagatgctca
    47581 tacggtagaa attgcagggc agctttatac cgcaccgcat attttgattg ccacaggagg
    47641 acatcctgtt tttccagata ttgagggggc acaatacggt atcagctcgg acggcttttt
    47701 tgccttagat gaggtaccaa aacgtacggc tgtggttggg gcaggctata ttgctgtgga
    47761 acttgctggt gttttgcatg ctttgggatc gaagacggat ttgtttatcc gtcacgatcg
    47821 acctttaaga agttttgaca aaaccattgt tgatgtctta gttgatgaaa tggcagttaa
    47881 tgggccgcgt ttacacactc atgcagaagt ggcaaaggtt gtcaaaaata ctgatgagtc
    47941 cttgaccctt tacctcaaag atggccaaga agttgaggtt gaccagctca tttgggctat
    48001 cggtcgcaag cctaatctag aagtttttag tcttgacaaa actggagtga cgttaaatga
    48061 taaaggttat attgagacag atgcctatga aaacacgtct gtcaaaggta tttatgccgt
    48121 gggagatgtt aatgggaaac tggctttaac tccagttgct gtggcagctg gacgtcgcct
    48181 atcagagcgt cttttcaata gcaaaacaga cgagaaattg gactaccaaa acgttgctac
    48241 tgtgattttt agtcaccctg ttattggctc tgttggcttg tcagaagaag cagcagtcaa
    48301 acagtatggg caagaagcag ttaaaacata tcaatcacgt tttacgtcta tgtttactgc
    48361 tatcactaac catcgccaac cttgtctgat gaagttggta acagtcggag ataccgaaaa
    48421 aatagttggt cttcacggaa tcggatacgg ggttgacgaa atgattcagg gctttgtagt
    48481 agccatcaaa atgggagcaa ccaaggcgga ttttgataac accgttgcta ttcacccaac
    48541 tggctcagaa gaatttgtca ccatgcgcta aaaaatgtag cctaaggcaa taaaaaatga
    48601 tgttaacagt ttttgaggaa agtcttctaa actgctagca tcgttttttg ttaggtgatt
    48661 aggggaatat gtttttaaag atatttgcgt tgctcagaca atattgcctt acctcggaga
    48721 taaaataaag tgaccctgta acaacaaaga gttcatcaga tgttacggaa ccttgtaacc
    48781 agtctctgta atcttttacc tgtgggtatt tatcaggata atcctctaaa agatttgctt
    48841 cagggaaatc aaaagtcgtg acagatactt caaaagtatc tagttgagcc agcaagtcgg
    48901 ctaaaggctt acgtttgaga cctgcaaaga gaatatgaat aggacgtttg ggaaattctt
    48961 cttgcagtag agactttaat ttagcaatgg aatctggatt gtgagcgccg tctaatagaa
    49021 gattaggttg aataaattcg gaccggccag gccaagttgt tgcctcaatt cctttttgaa
    49081 tcgtttttgg agatatttta ggaaaggatt ttctaagtaa ttgagctgtc ataatggcta
    49141 aacaggcatt cgctttttga tgttgaccta atagtttgag acggagtttg gttaaattca
    49201 agttatcgtg ttgaaaggaa aacgtctttt ctgaaggatt gagcaaaaaa tcttttccta
    49261 attgatataa gcgtgaaccg gctttttggg taacttgttg aaagacttga ctagcctcct
    49321 gctcaagttg accgataata acgggttctt tagctttgat aacttctgct ttttggtgag
    49381 caatttctgc taggctataa cctaaacgtt cttggtgatc aaaactaata gaagggcata
    49441 cgacggccag agcatgaaaa acattggttg cgtcggtttt cccaccaatc cctgcctcaa
    49501 taatggcaat atcaacaggt ttaagattgg caaagtagca aaacattatg agcgtcacta
    49561 actcaaactc ggtaggtcta tcccaatttg tttcaaggga cattttagtg agaatgggtc
    49621 taatcacgct cacacattgc gccaattcta ggtctgaaat gggctggcca ttaaggcaaa
    49681 tccgatcgtg aaaagagata ataaaaggag atgtaaaggt tccgacctga taaccagaag
    49741 ttgacaggat atgctgtaag taggctgtca cagagccctt gccgttagtt ccaacaacgt
    49801 gaatagcagg gaatttgtct tgtggccggc ctagtgcctc aagtaaccaa gccattctgg
    49861 ccaaatcggt cttgcgacca ttagccttaa aggtatgaat ccaggaaatg ctatcatagg
    49921 tagtcattac tatttcttgt ccttctaaca atgcttttaa gggttcgtag gaagaccagt
    49981 attagcatct tcagctccag ttgcattagg aagttgcgtc ccttcagtgg ttgatggtgt
    50041 ctcaggagct gtaggagtag tctcgttgtg agaaggtgcg gtagaagatg acggaagagt
    50101 tgtcttatta tcatctgtgg tttctgaagt acctgtatgg ttttgattac cctgagaaga
    50161 ctctttttca ataatcttga caatggtatt actcgattct ttgggtgtat cattagaggt
    50221 cttatctggt acaggctgca gtgctcttga aatggtaatg gttgccacga tgatactcaa
    50281 aatactacca ataagtgcaa tggatttttg gaaagctgta aaacctgttt taatatgctc
    50341 ggtagggaca cctcctgatt tacgaggttt ttgttgacgg gaataacgtg atgacatatt
    50401 tttctccttt aaaatcatcg taatgccaag attaaggagg aggaaacaga agtcctagct
    50461 cctctttaac acttcatcta tcagtataat ctagaaaaaa agtgaagtca acggtttacc
    50521 ttatgtctag gacaaggaag tcctttgggc ttattgtaat acgaatattc ttgatttcat
    50581 tttagctatt ttgtgataga ataaagtatt gagtaaaaat gaaggtgaca catgatttat
    50641 tttgataatg cagccacaac cataccttat ggagaggctc ttaaaactta ccaagaagta
    50701 gcaacaaaaa tatatggcaa tccctcaagt ctgcaccaat tagggacaaa tgcgtctcgt
    50761 attttagaag cttcccgtaa acagattgct ggtttgttgg gtgttaagtc agaagaaatc
    50821 ttttttacgt ctggtgggac tgaaagtgct aattgggcta ttaagggaat tgcttttgaa
    50881 aaaactgctt ttggcaaaca tattattatc tcagccattg aacaccctgc cgtgagtgaa
    50941 agtgtcaaat ggcttctcac acaaggattc gaagtttctt atgctccagt gacaacacag
    51001 ggagttgttg atgtgaatgc tttagctgag ctgattagac cagacaccat cttaatctcg
    51061 attatggctg ttaataatga aatgggagct atccaaccga ttagagccat ttcaaaccta
    51121 ttggctaacc aaccaacgat cacctttcac gttgatgctg ttcaagccat tggtaaaata
    51181 ccactctgtg attatatgac taatcgtgtg gatttggctt ctttttcagg gcacaaattt
    51241 catagtgttc gtggtgttgg cttcctttat aaaaaagcag gcaagcgact caatcctctc
    51301 ttgtcaggcg gcggccaaga gcaggagtta cgttcaacca ctgaaaatgt tgcaggaatt
    51361 gctagcatgg ccaaagcatt aagaatagtc actgaaaaac aagtgagcgt cttacctaaa
    51421 ctaacagcga tgcgagatgt gatttacaaa gctttgtccg cttacccaga tgtgacagta
    51481 ttttcagctc aagaaggctt tgcgcccaat attttgacct ttgggattag aggggttcga
    51541 ggagaagtta ttgtccacgc ctttgaaaaa tatgagattt atatttcgac cacaagtgca
    51601 tgttcgtcca aagcaggtaa gccagcagga agcctagtgg ctatggggat tcctgtaaaa
    51661 actgcccaga cagccgttcg tattagtcta gacgatgaca acgatatggg acaagtagag
    51721 caatttttga ccatattcaa acagatttat gataaaacac agaaagttag gtaagattag
    51781 gtaagatgga ctattcagaa attatggttc gccatggtga actatcaact aaagggaaga
    51841 atcgcatgcg attcattaac aaacttaaaa acaatattca agacgtactg gctcctttcc
    51901 cagccattac tgtccgttca gatcgtgaca gaactcatgt ctatttgaat ggcacagatt
    51961 accagccagt tgtagaagct ttaaagctgg tgtttggtgt tcaagctcta tctcctgttt
    52021 ataaacttga aaaaagtgtc cctcttttgg taacagctgt tcaagatatc atgacttctc
    52081 tttatcgtga tggactgacg tttaagattg ccactaagcg tagtgatcat gcgtttgaat
    52141 tggatagtcg tgagcttaac agtcttcttg gtggagctgt ttttgaggtt ttaccaaata
    52201 tccaagctca gatgaaacat cccgatgtga ctctcaaagt cgaaattcgt gatgaagcag
    52261 cttacatttc ttatgaagag attaagggag caggcgggtt accagtagga acgtcaggga
    52321 aagggatgct gatgttatcg ggcggtattg attcaccagt agctgggtat ttagccctta
    52381 aacgtggcct tgatattgaa gttgttcatt ttgctagccc tccgtacacc agtccaggtg
    52441 ccttggctaa agcccaagac cttactcgtc ggttaactcg ttttggtgga aatatccaat
    52501 ttatcgaggt tccttttaca gaaattcaag aagaaattaa aaataaggca ccagaggctt
    52561 accttatgac attaacccgc cgctttatga tgcgcatcac agatgccatt cgtgagcaac
    52621 gtaagggtct tgttattgtt aacggtgaga gcctaggtca ggttgctagt caaacccttg
    52681 aaagcatgca ggccattaat gcggtaacat caaccccaat tattagacca gtcgtgacaa
    52741 tggataaact tgaaattatc gagatggctc aggcgattga tacttttgac atttctattc
    52801 aaccgttcga agattgctgt actatttttg caccagaccg tcctaaaacc aaccctaaac
    52861 taggtaatgc tgaaaaatat gaagaacgct ttgatattga tggtcttgtc cagcgtgctg
    52921 tgtcaggaat tgttgtcaca gaaatcacac ctgaaatcgt caatgatgag gttgaaaatc
    52981 tcattgatgc tttactttaa aagaaaagat caagtgtaaa tcttttagta gtcagtaatg
    53041 atactattga aaagcctcta taagggcttt tttgctgcaa tgaaggagga aaattttgag
    53101 gcaagatgtt ataatagaga aaaaggaggg tgtgtcttga ttaaaactat tccatacaaa
    53161 aaaacgatgg cagcagttgt tgctcttatc gtcgcacttt tgctatttgg cttgatttat
    53221 gatttacttg gggttcaaaa aaataagcta gcagctcaaa aatctgctca gccaaaggtc
    53281 aaaacagcgc gtgttgtagc taatggcgac attttaattc atgatattct ctacatgagt
    53341 gctagaaaag ctgacgatac ctatgatttc actccttatt ttgaatatgt taaggactgg
    53401 attagcggtg ctgacttagc tattggagat tatgaaggga ccattagccc agattatccc
    53461 ttagcaggct atcccttatt caatgctcca gaagagattg caggtgctct gaaaaatact
    53521 ggctatgatg tagtcgattt agcccataat catatcttag attcccaatt agacggtgcc
    53581 cttaacacta aaaaggtttt tcatcaatta ggtatagaca gtattggcat ctatgacaag
    53641 gatcgttcaa aagaatcctt cttaattaaa aatgtcaatg gtatcaaaat tgcaatttta
    53701 ggttattctt atggttataa cggcatggag gccacactta gccaagaaga ctatgagaaa
    53761 cacatgtctg atttagatga agctaagata aaaaaagaac ttcagctagc tgaaaaaaag
    53821 gctgacgtga ccattgtcat gccacaaatg ggaacagaat atgccttaga accgacagca
    53881 gagcaaaaag aactttacca caaaatgatt gattggggag ctgacgtcgt cctaggaggc
    53941 catccgcatg ttattgaacc ttcagagaca gttataaaag gtaggcaaaa gaaattcatt
    54001 atttactcta tgggaaattt tatttcaaat cagcggcttg aaaccgtaga tgatatctgg
    54061 actgagcgtg gcctattgat ggaccttact tttgagaaaa aagttaacaa aacaaaaatt
    54121 aaaacagttg aggcccatcc aaccatggtt ttagccaaag gtaaaggcat tgtgggtaaa
    54181 gaaggttttg aactatacaa ttatcgaaca atggttttag aagattttat caaaggtgga
    54241 aaataccacg acaagattga tgaggaaacc aaagcaaaag tagcacttgc ttatcaggaa
    54301 attaatgatt tagttaacct gaaatggtaa tgtttggtgg tttagcatct a
//
LOCUS       DAXMQE010000010        53998 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.010, whole genome shotgun sequence.
ACCESSION   DAXMQE010000010 DAXMQE010000000
VERSION     DAXMQE010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 53998)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53998)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53998
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.010"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            complement(61..1824)
                     /gene="lpdA"
                     /locus_tag="ACF4ZO_000661"
     CDS             complement(61..1824)
                     /gene="lpdA"
                     /locus_tag="ACF4ZO_000661"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004148 - dihydrolipoyl dehydrogenase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HFD5486232.1"
                     /translation="MAVEIIMPKLGVDMQEGEIIEWKKQEGDTVNEGDILLEIMSDKT
                     NMELEAEDSGVLLKITRQAGETVPVTEVIGYIGAEGESVEVSSPAASDVNVARTTEDL
                     EAAGLEVPKAPAQAASAAPKAALADDEYDIIVVGGGPAGYYAAIRGAQLGGKIAIVEK
                     SEFGGTCLNVGCIPTKTYLKNAEILDGIKIAAGRGINLASTNYTIDMDKTVDFKNTVV
                     KTLTGGVQGLLKANKVTIFNGLGQVNPDKTVNIGSQTIKGRNVILATGSKVSRINIPG
                     IDSKLVLTSDDILDLREMPKSLAVMGGGVVGIELGLVWASYGVDVTVIEMADRIIPAM
                     DKEVSLELQKILSKKGMKIKTSVGVSEIVEANNQLTLKLNNGEEVVAEKALLSIGRVP
                     QMNGLENLNLEMDRNRIKVNDYQETSIPGIYAPGDVNGTKMLAHAAYRMGEVAAENAI
                     HGNTTRKANLKYTPAAVYTHPEVAMVGLTEEQAREQYGDVLIGKNSFTGNGRAIASNE
                     AHGFVKVIADAKYHEILGVHIIGPAAAEMINEAATIMESELTVDELLLSIHGHPTFSE
                     VMYEAFADVLGEAIHNPPKRK"
     gene            1857..2144
                     /locus_tag="ACF4ZO_000662"
     CDS             1857..2144
                     /locus_tag="ACF4ZO_000662"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486233.1"
                     /translation="MNFCGKSEIFDFVDAPTSGRLGLSETKIEESSDVYDAKISQLLP
                     FLSELFARVQLLITHLHEISSFYILSIFLRKGHPPSLNLAKSLLLLNAFLV"
     gene            complement(2155..3564)
                     /locus_tag="ACF4ZO_000663"
     CDS             complement(2155..3564)
                     /locus_tag="ACF4ZO_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045254 - pyruvate dehydrogenase complex
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HFD5486234.1"
                     /translation="MAFEIIMPKLGVDMQEGEIIEWKKQEGDTINEGDILLEIMSDKT
                     NMELEAEDSGVLLKIVRPAGDTVPVTEVIGYIGAEGESVDTIASSEKTTEIPVPASAD
                     AGPTVAPKENVASPAPQVAATAIPQGNGGKVRATPAARKAAAEMGIDLGQVPGTGPKG
                     RVHKEDVENFKGAQPKASPLARKIAADKGIDLATVSGTGFNGKVMKEDIIAILEAAKP
                     AEAKAPAAKEEKVVDLPEGVEHKPMSAMRKAISKGMTNSYLTAPTFTLNYDIDMTEMI
                     ALRKKLIDPIMAKTGLKVSFTDLIGMAVVKTLMKPEHEYMNASLINDANDIELHRFVN
                     LGIAVGLDDGLIVPVIHGADKMSLSDFVLASKDVIKKAQTGKLKAAEMSGSTFSITNL
                     GMFGTKTFNPIINQPNSAILGVGATIPTPTVVDGEIVARPIMAMCLTIDHRLVDGMNG
                     AKFMVDLKKLMENPFELLI"
     gene            complement(3749..4747)
                     /locus_tag="ACF4ZO_000664"
     CDS             complement(3749..4747)
                     /locus_tag="ACF4ZO_000664"
                     /EC_number="1.2.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HFD5486235.1"
                     /translation="MSETKLMALREAVNLAMTEEMRKDENIFLMGEDVGVYGGDFGTS
                     VGMIEEFGPKRVKDTPISEAAISGAAIGAAITGLRPIVDVTFMDFLTIMMDAIVNNGA
                     KNNYMFGGGLITPVTFRVASGSGIGSAAQHSQSLEAWLTHIPGIKVVAPGNANDAKGL
                     LKSAIRDNNIVLFMEPKALYGKKEEVNQDPDFYIPLGKGDIKREGTDLTIVSYGRMLE
                     RVLQAAEEVAADGINVEVVDPRTLIPLDKELIIESVKKTGKLMLVNDAYKTGGFIGEI
                     ATMITESEAFDYLDHPIVRLASEDVPVPYARVLEQAILPDVEKIKAAIVKMANKGN"
     gene            complement(4806..5774)
                     /locus_tag="ACF4ZO_000665"
     CDS             complement(4806..5774)
                     /locus_tag="ACF4ZO_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HFD5486236.1"
                     /translation="MVTVSKEQHLDMFLKMERIREFDSRINKLVRRGFVQGMTHFSVG
                     EEAANVGAVAHLSYDDIIFSNHRGHGQSIAKDMDLNKMMAELAGKATGVSKGRGGSMH
                     LADFEKGNYGTNGIVGGGYALAVGAALTQQYKGTNNIAVAFSGDGATNEGSFHESVNM
                     AATWKLPVIFFIINNRYGISMSINNATNTPHLYTRAEAYGIPGFYCEDGNDVMAVYET
                     MGKAVEHVRGGNGPAIVEVESYRWFGHSTADAGKYRTKEEVDEWKEKDPMIKYRTYLT
                     SEGIATDDELDAIQAQVKKEVDDAYEFAQNSPDPELSVAFEDVWVD"
     gene            complement(6060..7967)
                     /locus_tag="ACF4ZO_000666"
     CDS             complement(6060..7967)
                     /locus_tag="ACF4ZO_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HFD5486237.1"
                     /translation="MIILQGNKLERSFSGDVLFQNISLQVDERDRIALVGPNGAGKST
                     LLKLLVGEETPTSGEVNTKKDLTLSYLAQNSRFESDQTIYEEMLKVFEALRQDEKRLR
                     QMEMDMATVSGQDLTRLMTDYDLLTEHFRQQGGFTYESDIKAILNGFKFDESMWQMTI
                     AELSGGQNTRLALAKMLLEKPELLVLDEPTNHLDIETIAWLENYLANYQGALIIVSHD
                     RYFLDKVATVTLDLTPHGLDRYVGNYSRFMTLKAEKLVAEEKQFDKQQKEIAKLEDFV
                     QKNIVRASTTKRAQARRKQLEKIERLDKPTSARKSAHMTFQADKPSGNVVLTVEKAAI
                     GYNQHVLSEPINLDVHKLDAIAIVGPNGIGKSTLIKSVIGQIPFIKGEVKYGANVEIG
                     YYDQTQSHLTSSNTVLEELWQDFSTTPEVDIRNRLGAFLFSGDDVKKSVAMLSGGEKA
                     RLLLAKLSMENNNFLVLDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRLAT
                     KVLEITENGSTLYLGDYDYYLEKKAELEELARLAAGETVEETKEASATDYQLQKANQK
                     ERRRLTRRYEEIEARLETIEERIGAIQEDMHASNDTAQLIAWQKEWDQLDQEQETLME
                     EWETIAEQIES"
     gene            complement(8013..8339)
                     /locus_tag="ACF4ZO_000667"
     CDS             complement(8013..8339)
                     /locus_tag="ACF4ZO_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486238.1"
                     /translation="MKQLLAIILWLPKLIVKMFWHLIKGFLQTILLVTIIIIGLMYYS
                     NHSDSVLANKISIVTEQVVQIFDILTQKPSAKTRHGSGNSHSIFLVSAKEGNQRLKKS
                     SISFGN"
     gene            complement(8369..9154)
                     /locus_tag="ACF4ZO_000668"
     CDS             complement(8369..9154)
                     /locus_tag="ACF4ZO_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFD5486239.1"
                     /translation="MANIAIEYHSVVLGMERKVNVIYPDQSEIPKKDQGDKDIPVLYL
                     LHGMGGNENSWQKRTAIERLLRHTNLIVVMPSTDLGWYTDTAYGLNYYRALSQELPQV
                     LAAFFPNMTQKREKTFVAGLSMGGYGAFKWALKSNRFSYAASFSGALDFSPETLLEGN
                     LGELAYWQGVFGQFDDPDLDKHYLKNMVAESDGKTKFYAWCGYEDFLFATNEKAIADF
                     QAQGLDIDYHKGHGKHEWYYWNQQLEVLLEWLPINYQKEERLS"
     gene            complement(9287..10948)
                     /locus_tag="ACF4ZO_000669"
     CDS             complement(9287..10948)
                     /locus_tag="ACF4ZO_000669"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HFD5486240.1"
                     /translation="MTDIKMIALGGVREYGKNFYLVEINDSMFILDAGLKYPENEQLG
                     VDLVIPNLDYVIENKGKVQGIFLSHGHADAIGALPYLLAEVSAPVFGSELTIELAKLF
                     VKSNNSTKKFNNFHVVDSDTEIEFKDGLVSFFRTTHSIPESMGIVIGTDKGNIVYTGD
                     FKFDQAAREGYQTDLLRLAEIGKEGVLALLSDSVNATSNDQIASESEVGEEMDSVISD
                     ADGRVIVAAVASNLVRIQQVFDSATAHGRRVVLTGTDAENIVRTALRLEKLMITDERL
                     LIKPKDMSKFEDHELIILEAGRMGEPINSLQKMAAGRHRYVQIKEGDLVYIVTTPSTA
                     KEAMVARVENLIYKAGGSVKLITQNLRVSGHANGRDLQLLMNLLKPQYLFPVQGEYRD
                     LAAHAKLAEEVGIFPENIHILKRGDIMVLNDEGFLHEGGVPASDVMIDGNAIGDVGNI
                     VLRDRKVLSEDGIFIVAITVSKKEKRIISKAKVNTRGFVYVKKSHDILRESAELVNTT
                     VGNYLKKDTFDWGELKGNVRDDLSKFLFEQTKRRPAILPVVMEVR"
     gene            complement(11152..11910)
                     /locus_tag="ACF4ZO_000670"
     CDS             complement(11152..11910)
                     /locus_tag="ACF4ZO_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD5486241.1"
                     /translation="MTKIIELINATVDVDNGFEDAKTILDNVTLTIYEHDFLTILGGN
                     GAGKSTLFNVIAGTLSLTRGQIRILGQDVTHWPAEKRALYLSRVFQDPKMGTAPRMTV
                     AENLLIARQRGEKRSLASRKITEHLASFEDLVKRTGNGLEKHLETPAGLLSGGQRQAL
                     SLLMATLKKPALLLLDEHTAALDPKTSQSLMQLTDEFVTKDGLTALMITHHMEDALTY
                     GNRLIVMKDGNIIKDLNQMEKEQLTITDYYQLFD"
     gene            complement(11907..12776)
                     /locus_tag="ACF4ZO_000671"
     CDS             complement(11907..12776)
                     /locus_tag="ACF4ZO_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003064298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD5486242.1"
                     /translation="MIISSVSQGLIWGVLGLGIYLTFRILNFPDMTTEGSFPLGGAVA
                     VTAISLGWNPFLSTLLGMLSGALAGFLTGLLYTKGKMPTLLAGILVMTSCNSIMLMVM
                     GRANLGLHDHKRIQDCLPFSIDLNSLLTGLITVVIVISVLIYFLYTNLGQAYIATGDN
                     KDMAKSFGINTDWMEVMGLVVSNSLIALSGALVSQQDGYADVSKGIGVIVIGLASIIV
                     GEVLYSTGLTLLERLIAIVIGSILYQFLISVVITLGFNTSYLKLISALVLALCLMIPV
                     VKERYFKGVRLTR"
     gene            complement(13121..14119)
                     /gene="trpX"
                     /locus_tag="ACF4ZO_000672"
     CDS             complement(13121..14119)
                     /gene="trpX"
                     /locus_tag="ACF4ZO_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan ABC transporter substrate-binding
                     protein"
                     /protein_id="HFD5486243.1"
                     /translation="MKNKSLIATLLVLTVIVIGSLLSKGVSKENRDLANQQNITIGIL
                     QLVTHEALDDIKRGIEDQLKKQKPQKQNVVIKVMNAEGDQSKIQTMSRQLVQSGSDIV
                     IGIATPAAQGLAAASKDIPVVMSAVSDPVGSRLVMQLDQPEANVTGLSNKVPVKQTID
                     LMKKLTPHVKTVGILYASNEDNSLSQVKEFRRLARKKGYQVISYAVPSTNEVPATMSV
                     MLGKVDAVFIPQDNTIASAFSSVMTTSKAAKIPVYTSVDRMVEKGGLAAISQNQYDLG
                     VQTANQVLKLIKGKRVVDVPVKVVDIGQPLINKNVAAELGIAINREDFPSASFIEN"
     gene            14473..16125
                     /gene="fbp54"
                     /locus_tag="ACF4ZO_000673"
     CDS             14473..16125
                     /gene="fbp54"
                     /locus_tag="ACF4ZO_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein Fbp54"
                     /protein_id="HFD5486244.1"
                     /translation="MSFDGFFLHHLTNELKENLLYGRIQKVNQPFERELVLTIRNHRK
                     NYKLLLSAHPVFGRLQITQADFQNPQVPNTFTMIMRKYLQGAVIEQLEQIDNDRIIEI
                     KVSNKNEIGDAIQATLIIEIMGKHSNIILVDRAENKIIESIKHVGFSQNSYRTILPGS
                     TYIEPPKTAAVNPFTITDVPLFEILQTQELTVKSLQQHFQGLGRDTAKELAELLTTDR
                     LKRFREFFARPTQANLTTASFAPVLFSDSHATFETLSDMLDHFYQDKAERDRINQQAS
                     DLIHRVQTELDKNRNKLSKQEAELLATENAELFRQKGELLTTYLSLVPNNQDSVILDN
                     YYTGEKIEIALDKALTPNQNAQRYFKKYQKLKEAVKHLSGLIADTKQSITYFESVDYN
                     LSQASIDDIEDIREELYQAGFLKSRQRDKRHKRKKPEQYLASDGKTILMVGRNNLQNE
                     ELTFKMAKKGELWFHAKDIPGSHVIIKDNLDPSDEVKTDAAELAAYYSKARLSNLVQV
                     DMIEAKKLHKPSGAKPGFVTYTGQKTLRVTPDQAKILSMKLS"
     gene            complement(16185..17432)
                     /locus_tag="ACF4ZO_000674"
     CDS             complement(16185..17432)
                     /locus_tag="ACF4ZO_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003043897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HFD5486245.1"
                     /translation="MLNSEKMIASLDQQDLAHAEKYFQKALKEDDADSLIALGEYLES
                     IGFLPHAKRIYLQLADDYPELNINLAQIAAEDDAIEEAFLYLDKVSKDSPNYLSALLG
                     MADLYDMEGLTEVAREKLLQAVGISPEPLVIFGLAEIDMSLQYFKEAIDYYAQLDNRQ
                     ILELTGISTYQRIGRAYASLGKFEAAIEFLEKAVAIEYEDETVFELATLMYDQENYQK
                     ANLYFKQLETINPDYPGYEYGYALSLHEEHKTSEALRLVQQGLRKNAFDSQLLLLASQ
                     LSYELHDRQNAENYLLQAKEVAVDDEEILMRLVTLYFDAERFEEVIALNRETIDNVLT
                     KWTIAKAYHALEQEEVALALYNEISADLAENPEFLQDYAYLLREFGQFHKAIQMATAY
                     LRQVPDDVNMQDFLDHIKHQQSE"
     gene            complement(17422..18604)
                     /locus_tag="ACF4ZO_000675"
                     /pseudo
     CDS             complement(17422..18604)
                     /locus_tag="ACF4ZO_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990002.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
     gene            complement(18662..19138)
                     /locus_tag="ACF4ZO_000676"
     CDS             complement(18662..19138)
                     /locus_tag="ACF4ZO_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HFD5486246.1"
                     /translation="MTQLATICYIDNGDSLLLLHRNKKENDVHKGKWISVGGKLEAGE
                     TPDECARREILEETHLTVTEMAFKGIITFPEFTPGHDWYTYVFKVTGFEGDLISDEES
                     REGTLEWVPYDQVLEKPTWEGDYDIFKWILEDRPFFSAKFTYDQNNQLMDKSVTFY"
     gene            complement(19359..20399)
                     /gene="rfbB"
                     /locus_tag="ACF4ZO_000677"
     CDS             complement(19359..20399)
                     /gene="rfbB"
                     /locus_tag="ACF4ZO_000677"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000277597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008460 - dTDP-glucose 4,6-dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009225 - nucleotide-sugar metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HFD5486247.1"
                     /translation="MYKNIIVTGGAGFIGSNFVHYVYNNHPDVHVTVLDKLTYAGNRA
                     NIEAILGDRVELVVGDIADAELVDKLAAKADAIVHYAAESHNDNSLEDPSPFIHTNFI
                     GTYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGQGEGPGEKFTAETKYNPSSPYS
                     STKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILAGIKPKLYGE
                     GKNVRDWIHTNDHSTGVWAILTKGRIGETYLIGADGEKNNKEVLELILEKMGQPKDAY
                     DHVTDRAGHDLRYAIDSTKLREELGWEPQFTNFSEGLEETIKWYTENETWWKAEKDAV
                     EAKYAKTQEVIK"
     gene            complement(20643..21236)
                     /locus_tag="ACF4ZO_000678"
     CDS             complement(20643..21236)
                     /locus_tag="ACF4ZO_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018379055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HFD5486248.1"
                     /translation="MTETFFDKPLACREIKEIPGLLEFDIPVRGDNRGWFKENFQKEK
                     MLPIGFPERFFEEGKLQNNVSFSRQHVLRGLHAEPWDKYISVADDGKVLGAWVDLREG
                     ETFGNVYQTVIDASKGMFVPRGVANGFQVLSETVSYSYLVNDYWALDLKPKYAFVNYA
                     DPSLGITWENLAAAEVSEADKNHPLLSDVKPLKPKDL"
     gene            complement(21236..22105)
                     /gene="rfbA"
                     /locus_tag="ACF4ZO_000679"
     CDS             complement(21236..22105)
                     /gene="rfbA"
                     /locus_tag="ACF4ZO_000679"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002276675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008879 - glucose-1-phosphate
                     thymidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0045226 - extracellular polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HFD5486249.1"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPIYDKPMIYYPLSTLMLA
                     GIKDILIISTPQDLPRFEELLGDGSEFGISLSYKEQPSPDGLAQAFIIGEEFIGDDRV
                     ALILGDNIYHGNGLTKMLQKAAAKEKGATVFGYQVKDPERFGVVEFDENMNAISIEEK
                     PEVPKSHFAVTGLYFYDNDVVEIAKNIKPSARGELEITDVNKAYLERGDLSVELMGRG
                     FAWLDTGTHESLLEAAQYIETVQRLQNAQVANLEEIAYRMGYISKEDVHKLAQSLKKN
                     EYGQYLLRLIGEA"
     gene            complement(22163..23269)
                     /locus_tag="ACF4ZO_000680"
     CDS             complement(22163..23269)
                     /locus_tag="ACF4ZO_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFD5486250.1"
                     /translation="MKIAIIGAGIVGSTAAYYLQQSDQKEVTIFDHGQGQATKAAAGI
                     ISPWFSKRRNKVWYRMARLGADFYQQLINDLKEDGFATDFYQQNGIYVLKKQEEKLRD
                     LYELALARKVESPIIGELAIKNRKELGNDFKGLIGFDNCLYASGAARVEGAALCETLL
                     KASGYPVIRQKVTLKQQGSGYEIAGHYFDQVILAAGAWLPDLLRPLGYQVDVRPQKGQ
                     LLDYDVHHIISDNYPVVMPEGEIDLIPFNQGKISVGASHENDKGYDLEPDWQVLEKLE
                     MQALTYLPLLKEATQKTCRVGIRAYTSDYSPFYGQVPGLKNLYTASGLGSSGLTVGPL
                     IGYELAQLLLGHEGLLTPSDYSPEPYLLRSTGKA"
     gene            complement(23309..24097)
                     /locus_tag="ACF4ZO_000681"
     CDS             complement(23309..24097)
                     /locus_tag="ACF4ZO_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019781659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051540 - metal cluster binding [Evidence
                     IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HFD5486251.1"
                     /translation="MKAKILIDAYEAFCPLDLSMEGDVKGLQMGSLDKDIRKVMITLD
                     IRESTVAEAIKNEVDLIITKHAPIFKPLKDLVSSPQRDILLDLVKHDISVYVSHTNID
                     IVPGGLNDWFCDLLEIKEATYLSETKEGFGIGRIGTVKEQALEELASKVKRVFDLDTV
                     RLIRYDKENPLISKIAICGGSGGEFYQDAVQKGADVYITGDIYYHTAQEMLTEGLFAV
                     DPGHHIEVLFTEKLKEKLQGWKEENGWDVSIISSKASTNPFSHL"
     gene            complement(24087..24773)
                     /locus_tag="ACF4ZO_000682"
     CDS             complement(24087..24773)
                     /locus_tag="ACF4ZO_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine(22)-N(1))-methyltransferase TrmK"
                     /protein_id="HFD5486252.1"
                     /translation="MDSQLSNRLAQVAAYVPKGVKLLDVGSDHAYLPIFLVETNQISA
                     AIAGEVVRGPYESALKNVTQSGLAEHIQVRLANGLAAFEEADDVTAITICGMGGRLIA
                     DILEAGKEKLQGIERLVLQPNNREDDLRAWLSVNAFKIVAETIMAENDKYYEIIVAEH
                     GEKALSATELRFGPYLSQEKSVVFKEKWQREMDKLAYALSCIPEEKTQERQLLLTKIQ
                     QIKEVIVHES"
     gene            complement(24845..25501)
                     /gene="nth"
                     /locus_tag="ACF4ZO_000683"
     CDS             complement(24845..25501)
                     /gene="nth"
                     /locus_tag="ACF4ZO_000683"
                     /EC_number="4.2.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140078 - class I DNA-(apurinic or
                     apyrimidinic site) endonuclease activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HFD5486253.1"
                     /translation="MRIGKARLAKVLTIIGQMFPEAKGELDWETPFQLLIAVILSAQT
                     TDKAVNKVTPGLWQSYPEIEDLAFAELSDVENALRTIGLYKNKAKNIIKTAQAIRDDF
                     KGQVPKTHKELESLPGVGRKTANVVLAEVYGVPAIAVDTHVARVSKRLNISSPDADVK
                     QIEADLMAKIPKKDWIITHHRLIFFGRYHCLAKKPKCEICPVQSYCKYYQNTYGKSKA
                     "
     gene            complement(25498..26181)
                     /locus_tag="ACF4ZO_000684"
     CDS             complement(25498..26181)
                     /locus_tag="ACF4ZO_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HFD5486254.1"
                     /translation="MSFLEHYKSGNLVIPSALLFHYKDLFKSSDDFLVWQFFYLQNTT
                     KRDDLAPSQIAHALGKSVADINKIISSLTSQGLLDMRTIELTGEIEIIFDASPVLAKL
                     DQLFVSQTATEIDKQETPNHFKRLVDEFERELGRFLSPFELEDLEKTLRDDKTDPDLI
                     REALKEAVFNGKTNWKYIQAILRNWRKEGIVNLRQVEERRRVREGEDLSQVTISDDFL
                     SAMNLWSDS"
     gene            complement(26262..26780)
                     /locus_tag="ACF4ZO_000685"
     CDS             complement(26262..26780)
                     /locus_tag="ACF4ZO_000685"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003999 - adenine
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0006168 - adenine salvage [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HFD5486255.1"
                     /translation="MDLTNYIASIKDYPKAGITFRDISPLMADGKAYSYAIREIAQYA
                     CDKDIDMVVGPEARGFIIGCPVAVELGIGFAPVRKPGKLPRDVVSADYEKEYGLDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGIVAGCAFLIELEGLNGRHAIR
                     NYDYKVLMQFPG"
     gene            complement(26930..29140)
                     /gene="recJ"
                     /locus_tag="ACF4ZO_000686"
     CDS             complement(26930..29140)
                     /gene="recJ"
                     /locus_tag="ACF4ZO_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008409 - 5'-3' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HFD5486256.1"
                     /translation="MIKSKYSWKIKDKKPDDGFFKLAKTKGLTQTAAQLIYERGIRTE
                     EALDELLTADLSQLHDPYLLHDMAKAVPRIRQAIEEGERILIYGDYDADGMTSASIVK
                     ETLDMMGAEPLVYLPNRFTDGYGPNQSVYKYFIEQEAVSLIITVDNGVAGHEAIRYAQ
                     EQEVDVIVTDHHSLPEELPEAFAIIHPEHPDADYPFKHLAGCGVAFKLATALLESLPT
                     DCLDLVAIGTIADMVSLTGENRVLVKNGLAMLKHTERVGLQELMSLSPIDLEHFNEDA
                     IGFQIAPQLNALGRLDDPNPAIELLTGFDDQEAQAIALMIKKKNEERKALVQDIFDQA
                     MAMVDPQKPVQVLAQAGWHPGVLGIVAGRIMETIGQTVVVLTIDNGFAKGSARSLEAI
                     NIFEALNGKRELFTAFGGHAGAAGMTLPVDNLEALSDFLCQFVIERGLDQTAKNTLTI
                     DERLSLDDLSLDILKSLDKLAPYGMDHQKPVFYVKDIRVSQARTIGQDQSHLKFKVSQ
                     GKASFDVLAFGQGSQLQEFRQATGLELAVTLSVNHWNGNTSLQFMLVDARVDGVQLLD
                     LRTKTAKVPEGIPTIEEDPNARVILINDIPEDFKTWRNQFVHKDFDAIYFKNQMKYPY
                     YLTGFGSREQFAKLYKTIYQFPEFDLRHKLTELSHYLNIEKLLLIKLIQIFEELSFVT
                     IDDGLMTVNPQAQKREISESHIYQDLKELVKFQEIMALASPKEMYDYLVKSNDQ"
     gene            complement(29137..29901)
                     /locus_tag="ACF4ZO_000687"
     CDS             complement(29137..29901)
                     /locus_tag="ACF4ZO_000687"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HFD5486257.1"
                     /translation="MAQRIIVITGASGGLAQAIVKQLPKEDSLILLGRNKERLEHCYQ
                     HIDNKECLELDITNPVAIEKMVAQIYQRYGRIDVLINNAGYGAFKGFEEFSAQEIADM
                     FQVNTLASIHFACLIGQKMAEQGQGHLINIVSMAGLIASAKSSIYSATKFALIGFSNA
                     LRLELADKGVYVTTVNPGPIATKFFDQADPSGHYLESVGKFTLQPNQVAKRLVSIIGK
                     NKRELNLPFSLAVTHQFYTLFPKLSDYLARKVFNYK"
     gene            complement(29901..30830)
                     /gene="rnz"
                     /locus_tag="ACF4ZO_000688"
     CDS             complement(29901..30830)
                     /gene="rnz"
                     /locus_tag="ACF4ZO_000688"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016891 - RNA endonuclease activity,
                     producing 5'-phosphomonoesters [Evidence IEA];
                     GO_process: GO:0042780 - tRNA 3'-end processing [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HFD5486258.1"
                     /translation="MELQFLGTGAGQPAKQRNVSSLALKLLDEINEVWMFDCGEGTQR
                     QILETTIKPRKIRKIFITHLHGDHIFGLPGFLSSRSFQASEEQTDLDIYGPIGIKTYV
                     LTSLKVSGARVPYQIHFHEFDDKSLGKIMETDKFVVYAERLAHTIFCMGYRVVQKDLE
                     GTLDAEALKAAGVPFGPLFGKIKNGQDVELEDGRLICAKDYISAPKKGKIITIIGDTR
                     KTSASVKLAKDADVLVHESTYGKGDERIARNHGHSTNMQAAQIAHEAGAKRLLLNHVS
                     ARFLGRDCRQMEKDAATIFENVKMVQDLEEVII"
     gene            complement(30845..31480)
                     /locus_tag="ACF4ZO_000689"
     CDS             complement(30845..31480)
                     /locus_tag="ACF4ZO_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003043928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HFD5486259.1"
                     /translation="MNNYIDLAKTYGGFTSLDTNYLNHLLASLTDQQKLAFITPPPSV
                     INAYFAEIYQKQSPQAATDYYFNLSKALGLFTDQPSFEEEKPFVRLNLSGKAYGFAYQ
                     NDQEVALVFSEKAEPKKPELFFELTQIFPQYMVYEDKGQLKMQAKQFEQGECEDITPD
                     DTLLSKIYRLANGITMLKGFNVEELWALSQTFSGQKYYDFDQREFMIYITQ"
     gene            complement(31473..32711)
                     /gene="hflX"
                     /locus_tag="ACF4ZO_000690"
     CDS             complement(31473..32711)
                     /gene="hflX"
                     /locus_tag="ACF4ZO_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HFD5486260.1"
                     /translation="MIETKRQQERVILLGVELQTTEHFDMSMTELANLAKTAGVKVMA
                     SFSQKRERYDSKTFIGSGKLDEIKAIVEADEIDAVIVNNRLTARQNANLEAVLEVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYMLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSIRHQIADIERQLTQVEKNRQKIRDRRVGSDTFKIGLIGYTNAGKSTIMNLL
                     TDDSHYEANELFATLDATTKQLYLENQFQATLTDTVGFIQDLPTELVAAFKSTLEESK
                     YVDLLLHVIDASDPNHSEQEKVVLNLLKELDMLNIPRLAIYNKVDIAEQFTATAFPNI
                     RISARSKDSKILLRRLIIDQIRDQFVPFRIKVHQDKAYKLYDFNRVALLDHYTFDQEI
                     EDISGYISPKQQWRLDDFYE"
     gene            complement(32784..33683)
                     /gene="miaA"
                     /locus_tag="ACF4ZO_000691"
     CDS             complement(32784..33683)
                     /gene="miaA"
                     /locus_tag="ACF4ZO_000691"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0052381 - tRNA dimethylallyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HFD5486261.1"
                     /translation="MTKIKIVVIVGPTAVGKTALGISLAKALNGEIISGDSQQVYRQL
                     DVGTAKATQEEQEAAVHHLIDIREVTESYSAYEFVQDAQKAISDIVSRGKLPIIVGGT
                     GLYLQSLLEGYHLGGQVDQEAVKAYRQELDQLSDQEVYELLQVKSITIKQLNRRRAIR
                     ALELSQFADDLENAETAYEPLIIGLNDDRQVIYDRINQRVDRMLENGLLEEAKWLYEH
                     YPTVQASRGIGYKELFPYFVGEMTLAEASDQLKQNTRRFAKRQLTWFRNRMAVNFTAI
                     TAPDYPQVVHDRVRDFLGQKEKS"
     gene            33817..33993
                     /locus_tag="ACF4ZO_000692"
     CDS             33817..33993
                     /locus_tag="ACF4ZO_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002263068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HFD5486262.1"
                     /translation="MVKKYQFVKGLATGVLATAATVAGAVFAVKKTIIDPEEEKAAFI
                     EENRKKAARRRVAR"
     gene            complement(34111..35019)
                     /locus_tag="ACF4ZO_000693"
     CDS             complement(34111..35019)
                     /locus_tag="ACF4ZO_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HFD5486263.1"
                     /translation="MKHLKNPPLVMSGLALGTLSFGNLLATYVSIFSYLGILAALFIY
                     GILLVGMVRNLNDTKMQLRQPLIASVFPTFFMTGMLLSSLFLKVTGGCWLGFLTWWLF
                     FLGNLVLIAYYQYRFVFSFSWDNVFPSWSVLFVGIAMAALTAPASRQFLLGQVIFWVC
                     LLLTAVILPFMAKKTYGIGLGQAVMPNISTFCAPLSLLSASYLATFPRPQVGMVIFLL
                     VSSQLLYAFVVVQLPRLLNRPFNPGFSAFTFPFVISATSLKMTLSFLGWQGLGWQALL
                     LGEVLLATALVTYVYGAYLRFLFQNK"
     gene            complement(35256..35675)
                     /locus_tag="ACF4ZO_000694"
     CDS             complement(35256..35675)
                     /locus_tag="ACF4ZO_000694"
                     /inference="COORDINATES: protein motif:HMM:NF012273.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione binding-like protein"
                     /protein_id="HFD5486264.1"
                     /translation="MPFIAKQTLKSQLIPQDNLLAESRFNEIMDFLTGDFPLVFRPMF
                     NPHRYTISQDNQALEKVKQASYKRMDIAMTHLDGLIGESGHVYRDQQTIADAYAYAMA
                     LWSQKTPKSYENYPHLAAFMAKMVEDSAVQQVLNAAH"
     gene            complement(35724..35870)
                     /locus_tag="ACF4ZO_000695"
     CDS             complement(35724..35870)
                     /locus_tag="ACF4ZO_000695"
                     /inference="COORDINATES: protein motif:HMM:NF012697.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486265.1"
                     /translation="MQSHQQRRRQHQLCLEPFQKNCEFLYYEVEKVKLDSEDCLTINP
                     LGMV"
     gene            complement(35986..36972)
                     /locus_tag="ACF4ZO_000696"
     CDS             complement(35986..36972)
                     /locus_tag="ACF4ZO_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HFD5486266.1"
                     /translation="MSEKIRVLLYYKYVSIENAQEYAAKHLEFCKSIGLKGRILIADE
                     GINGTVSGDYETTQKYMDWVHSDERFADLWFKIDEENQQAFRKMFVRYKKEIVHLGLE
                     DNNFDSDINPLETTGKYLNPKQFKEALLDEDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKDKFMEKRVVVYCTGGVRCEKFSGWMVREGFKDVGQLHGGIATYGKD
                     PEVQGELWDGAMYVFDDRISVPINHVNPTVISKDYFDGTPCERYVNCANPFCNKQIFA
                     SEENETKYVRGCSPECRAHERNRYVQENGLSRQEWAERLEAIGESLPEFVGA"
     gene            37172..37474
                     /locus_tag="ACF4ZO_000697"
     CDS             37172..37474
                     /locus_tag="ACF4ZO_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486267.1"
                     /translation="MTYELCLEYGTYPLSRVDAYWGEDQNPPTFIQEDRLLCHKLETM
                     NHLFHDLFVTIESQFHYVGFNMPEKRAQIRILYQEVATILKSKYKDYPIKIETFLL"
     gene            38274..39029
                     /locus_tag="ACF4ZO_000698"
     CDS             38274..39029
                     /locus_tag="ACF4ZO_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0090729 - toxin activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exotoxin OB-fold domain-containing protein"
                     /protein_id="HFD5486268.1"
                     /translation="MKNNKKVLKKIVYFVLAIFLGLTTSQEVFAQQDPNPSQLHRSSL
                     VKNLQNIYFLYEGDPVVHENVKSVDQLLSHDLIYNVSGLNYDKLKTELKNREMSTLFK
                     NKNVDIYGVEYYYHCYLCRNAKRRACIYGGVTNHEGNHLEIPKNILVKVSIDGIQSLS
                     FDIETSKKMVTAQELDYKVRKHLTDNKQLYTNGPSKYETGYIKFISKDKETFWFDFFP
                     EPEFNQVKYLMIYKDNETLDSSTSQIEVYLTTK"
     gene            complement(39333..39437)
                     /locus_tag="ACF4ZO_000699"
                     /pseudo
     CDS             complement(39333..39437)
                     /locus_tag="ACF4ZO_000699"
                     /inference="COORDINATES: protein motif:HMM:NF024729.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(39523..39780)
                     /locus_tag="ACF4ZO_000700"
     CDS             complement(39523..39780)
                     /locus_tag="ACF4ZO_000700"
                     /inference="COORDINATES: protein motif:HMM:NF012870.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DDE-type integrase/transposase/recombinase"
                     /protein_id="HFD5486269.1"
                     /translation="MARNFYVTNSNEKWGTDVTGFKIPSSHNKLYLSAILDAPPVAFV
                     ISGRNDDRLVFKAFDKVIKASPTAKSIFHSDRGFQYTNKYF"
     gene            complement(39991..40206)
                     /locus_tag="ACF4ZO_000701"
     CDS             complement(39991..40206)
                     /locus_tag="ACF4ZO_000701"
                     /inference="COORDINATES: protein motif:HMM:NF014875.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exotoxin beta-grasp domain-containing protein"
                     /protein_id="HFD5486270.1"
                     /translation="MIFIIIENKKYPKGTVTLDLNSGKYIVFDLYYFCNGDFNSVLKI
                     YSNNERVASTQFHVDNSIGYLNFLEVY"
     gene            complement(40169..40285)
                     /locus_tag="ACF4ZO_000702"
     CDS             complement(40169..40285)
                     /locus_tag="ACF4ZO_000702"
                     /inference="COORDINATES: protein motif:HMM:NF014875.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exotoxin beta-grasp domain-containing protein"
                     /protein_id="HFD5486271.1"
                     /translation="MFITINKPQVTAQEVEIKVRNLLIRKYNIYNNREQKIP"
     gene            complement(40255..40476)
                     /locus_tag="ACF4ZO_000703"
                     /pseudo
     CDS             complement(40255..40476)
                     /locus_tag="ACF4ZO_000703"
                     /inference="COORDINATES: protein motif:HMM:NF013303.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0090729 - toxin activity [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="exotoxin OB-fold domain-containing protein"
     gene            complement(40749..41045)
                     /locus_tag="ACF4ZO_000704"
     CDS             complement(40749..41045)
                     /locus_tag="ACF4ZO_000704"
                     /inference="COORDINATES: protein motif:HMM:NF014875.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exotoxin beta-grasp domain-containing protein"
                     /protein_id="HFD5486272.1"
                     /translation="MSTDKKEVAIQEFDVKSRYYLQKHFNICGFSDVKNFGRSSRFKS
                     GLEEGNIVFHLNSGEKISYNLFDTEFGDRESILKSTVGLSDQLYIDIDLVEFNK"
     gene            complement(41129..41248)
                     /locus_tag="ACF4ZO_000705"
                     /pseudo
     CDS             complement(41129..41248)
                     /locus_tag="ACF4ZO_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001006816.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3102 domain-containing protein"
     gene            41352..41609
                     /locus_tag="ACF4ZO_000706"
     CDS             41352..41609
                     /locus_tag="ACF4ZO_000706"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486273.1"
                     /translation="MGIIISKNFSLAVVASSSSDLSIEDKIKLYEDTIIAIEALNKPL
                     IDAKNKKITDNFKLLEKSILVANHFFVHNISSSIVVDFISF"
     gene            complement(41596..41847)
                     /locus_tag="ACF4ZO_000707"
     CDS             complement(41596..41847)
                     /locus_tag="ACF4ZO_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HFD5486274.1"
                     /translation="MTKKQRLKQEHLKPKKRLKEKRLKREYTEMYMADLIDLKNRKGY
                     SEKEDGLQPFKDYEMAIISQKFNVSESGLFFKYKYLKMR"
     gene            41903..42694
                     /locus_tag="ACF4ZO_000708"
     CDS             41903..42694
                     /locus_tag="ACF4ZO_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019792358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4393 domain-containing protein"
                     /protein_id="HFD5486275.1"
                     /translation="MNTTVSTILVSLGTNLATDAVQKANNPARAIDDLMTLIGFEKIH
                     AWAEKARIKHAADLDDFKHKLAEEILQIATDKLKDPSLNILGPALEASKYHIEQETIR
                     NMFARLIASDIDSSKENLVHPSFVEIIKQLSPLDAQNLSIIFNYKYTDIPVANYYLTY
                     KNGRGMKLAHPDVFLLNPEQNMLDYNSSSLENLRRMGIIEILYNQSKHDEHQYSLLRN
                     NNYLDDIAKHTQSNDPNFQDIYVQPGITRLTYFGQDFCETCLPPK"
     gene            43041..43784
                     /locus_tag="ACF4ZO_000709"
     CDS             43041..43784
                     /locus_tag="ACF4ZO_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HFD5486276.1"
                     /translation="MANLSDNIKYFRKQNKLTQKELAKKLKIAPTAISAWEVGRNKPL
                     MDNIEQMTSIFGIPKSKLLGDEIYKIQETASPELIPSTLQKITATSSQLEHSRQLIVL
                     DTAETLLNQQKEIKNNEDTVVELFSYNYYDQPASAGTGQYLNDVQVETIELPVDYDAD
                     FVIPVYGDSMGPEYHSEDYVFVKLSVDLSDGDIGVFEYYGDAYIKQLLINAEGAFLHS
                     FNSKYDDIPIDRDSDFRIIGEVIGSYSEK"
     gene            43844..44314
                     /locus_tag="ACF4ZO_000710"
     CDS             43844..44314
                     /locus_tag="ACF4ZO_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486277.1"
                     /translation="MKELQLTNIEAQQLITLLKVIATQHNKTLTNNTSGHIDIVGQNH
                     KRFILNYFYSTNSKVFHLRETEHNYTLIRINLNNKFHKNSNGEKIWGNRINIFSEEEY
                     YLKADESTHYKAYPLPYETIKDTNDFLEMMSNLFDYTNINNPQDANINIQEDLI"
     gene            44340..45116
                     /locus_tag="ACF4ZO_000711"
     CDS             44340..45116
                     /locus_tag="ACF4ZO_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000994488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1828 domain-containing protein"
                     /protein_id="HFD5486278.1"
                     /translation="MKASDVKKEYLAFVKENTIFNNATETHTEVVTPFVDPFGEAIGF
                     SIKSNGKSLTITDDSYTIWNLSINGIDVTKKGRRNDLFLSLLHYNGFDLVDKAIERTV
                     AKANLGQAIHDMTQLLMNVYDFIQLSPNNVKSQFLDDVKSYFMSDNHYSVFPAFSIAG
                     RSRLEHRFNFVFMSHGISKIARVHNHVTKQQVDTILASWLDTSEFRKREYGDKEELYI
                     IVSDDGFKNMKDDHLIALQEYNIHILNFADKQQLQMQLGK"
     gene            complement(45221..46573)
                     /locus_tag="ACF4ZO_000712"
                     /pseudo
     CDS             complement(45221..46573)
                     /locus_tag="ACF4ZO_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611511.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(46653..46724)
                     /locus_tag="ACF4ZO_000713"
     tRNA            complement(46653..46724)
                     /locus_tag="ACF4ZO_000713"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(46689..46691),aa:Arg,seq:ccg)
     gene            complement(46837..48042)
                     /gene="rpsA"
                     /locus_tag="ACF4ZO_000714"
     CDS             complement(46837..48042)
                     /gene="rpsA"
                     /locus_tag="ACF4ZO_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002997242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HFD5486279.1"
                     /translation="MNEFEDLLNSVSEVNPGDVVTAEVLTVDNGQANVVIEGTGVEGV
                     LTLRELTNDRDADINDFVKAGDTVEVLVLRQVVGKDTDTVTFLVSKKRLEARKAWDKL
                     VGREGEVVTVKGTRAVKGGLSVEFEGLRGFIPASMIDTRFVRNTEKFVGQEFDAKIKE
                     VDAAENRFILSRREVIEEAAKEARAEVFSKISEGAVVTGTVARLTSFGAFIDLGGVDG
                     LVHVTELSHERNVSPKSVVSVGEEVEVKVLSIDEEAGRVSLSLKATTPGPWDGVEQKL
                     AQGDVVEGKVKRLTDFGAFVEVLPGIDGLVHISQISHKRVENPKDVLSVGQEVTVKVL
                     EVNAADERVSLSIKALEERPAQAEGDNKEEKRQSRPRRPKRESRRDYELPETQTGFSM
                     ADLFGDIEL"
     gene            complement(48169..48240)
                     /locus_tag="ACF4ZO_000715"
     tRNA            complement(48169..48240)
                     /locus_tag="ACF4ZO_000715"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(48206..48208),aa:Gln,seq:ttg)
     gene            complement(48291..48371)
                     /locus_tag="ACF4ZO_000716"
     tRNA            complement(48291..48371)
                     /locus_tag="ACF4ZO_000716"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(48335..48337),aa:Tyr,seq:gta)
     gene            complement(48432..48662)
                     /locus_tag="ACF4ZO_000717"
     CDS             complement(48432..48662)
                     /locus_tag="ACF4ZO_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HFD5486280.1"
                     /translation="MSKKDKKIEIQLIDYKVMVNETKIDGYQLQIGKRVVGEIAELDE
                     KFAVLKNDGVDCFFKTLEQAVENIIENYNLNH"
     gene            complement(48726..49748)
                     /locus_tag="ACF4ZO_000718"
     CDS             complement(48726..49748)
                     /locus_tag="ACF4ZO_000718"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012961903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004084 - branched-chain-amino-acid
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0009081 - branched-chain amino acid
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HFD5486281.1"
                     /translation="MTIAIDWDNLGFEYHKLPFRYISYYKNGQWDKGQLTEDATLHIS
                     ESAPALHYGQQAFEGLKAYRTKDGSIQLFRPDRNAARLQATADRLLMPQVSTEQFIDA
                     AKQVVKANEDFVPPYGTGATLYLRPLLIGVGDIIGIKPAEEYIFTIFAMPVGNYFKGG
                     LAPTNFIVSEAFDRAAPYGTGAAKVGGNYAGSLLPGKAAKSAGFSDVIYLDPATHTKI
                     EEVGAANFFGITANNEFVTPLSPSILPSITKYSLLQLAEERLGMTVIEGDVPINELDK
                     FVEAGACGTAAVISPIGGIQYKDNLHVFYSETEVGPVTRRLYDELVGIQFGDIEAPEG
                     WIVKVD"
     gene            complement(49871..52330)
                     /gene="parC"
                     /locus_tag="ACF4ZO_000719"
     CDS             complement(49871..52330)
                     /gene="parC"
                     /locus_tag="ACF4ZO_000719"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021340535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HFD5486282.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQERALPDIRDGLKPVQRRI
                     LYSMNKDGNTFEKGYRKSAKSVGNIMGNFHPHGDASIYDAMVRMSQDWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKNTVSFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSSGISAGYATDIPPHNLSEVIDAVVYMIDHPKASLEKLMEFLPGPDFPTGGI
                     IQGADEIKKAYETGKGRVVVRSRTEIEELKGGKQQIIVTEIPYEVNKAVLVKKIDDVR
                     VNNKVPGIVEVRDESDRTGLRIAIELKKEADSQTILNYLLKYTDLQVNYNFNMVAIDH
                     FTPRQVGLQKILSSYISHRKDIIIERSKFDKAKAEKRLHIVEGLIRVLSILDEIIALI
                     RSSDNKADAKENLKVSYDFSEEQAEAIVTLQLYRLTNTDIVTLQNEENDLRDLITTLS
                     AIIGDEATMYNVMKRELREVKKKFANPRLSELQAESQIIEIDTASLIAEEETFVSVTR
                     GGYLKRTSPRSFNASSLEEVGKRDDDELIFVKQAKTTEHLLLFTTLGNVIYRPIHELT
                     DLRWKDIGEHLSQTISNFATEEEILYADIVTSFDQGLYVAVTQNGFIKRFDRKELSPW
                     RTYKSKSTKYVKLKDDKDRVVTLSPVIMEDLLLVTKNGYALRFSSQEVPIQGLKSAGV
                     KGINLKNDDSLASAFAVTSNSFFVLTQRGSLKRMAVDDIPQTSRANRGLLVLRELKTK
                     PHRVFLAGGVQSDASAEQFDLFTDIPEEETNQQMLEVISKTGQTYEIALETLSLSERT
                     SNGSFISDTISDQEVLVARTR"
     gene            complement(52421..>53998)
                     /gene="parE"
                     /locus_tag="ACF4ZO_000720"
     CDS             complement(52421..>53998)
                     /gene="parE"
                     /locus_tag="ACF4ZO_000720"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HFD5486283.1"
                     /translation="SVVNALSAWLEVEITRDGAVYRQRFENGGKPVTTLKKVGTAPKS
                     KSGTVVTFMPDDKIFSTIDFKFNTISERLKESAFLLKNVKMSLTDLRGDDPIIEEFHY
                     ENGVQDFVEYLNEDKETLTPVIYMEGQDQDFQVEVALQYNDGFSDNILSFVNNVRTKD
                     GGSHETGLKSAITKAMNDYARKTNLLKEKDKNLEGSDYREGLSAVLSILVPEQHLQFE
                     GQTKDKLGSPLARPIVESIVSEKLTFFLLENGEVTSHLVRKAIKARDAREAARKARDD
                     SRNGKKNKKDKGLLSGKLTPAQSKNAKKNELYLVEGDSAGGSAKQGRDRKFQAILPLR
                     GKVLNTEKAKMADILKNEEINTMVYTIGAGVGADFNLEDINYDKIIIMTDADTDGAHI
                     QTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKTEKIAYAWTDGELEDLRREFG
                     KGAILQRYKGLGEMNANQLWETTMDPETRTLIRVTIDDLARAERRVSVLMGDKAAPRR
                     QWIEDNVKFTLEENTVF"
BASE COUNT        16398 a        11313 c         9314 g        16973 t
ORIGIN      
        1 gtcttttttg tgatctgtta tgtgatgata tttttcatta gttaataaga caaagacgtt
       61 ttacttacgt tttggtgggt tatggatagc ttcgccaagc acatctgcaa aggcttcgta
      121 catcacttca gagaaagttg ggtgtccatg aattgataat aacaattcat caacggttaa
      181 ttcagattcc ataatagtag ctgcttcatt aatcatctca gctgcagctg gaccaataat
      241 atgaacacct aagatttcgt ggtatttggc atcagcaata actttaacaa aaccatgtgc
      301 ttcatttgaa gcaatcgcgc gtccattacc agtaaagctg tttttaccaa taagcacgtc
      361 accatattgt tcacgggctt gttcttcagt taaaccaacc attgccactt cagggtgtgt
      421 gtaaacggct gctggagtgt atttaaggtt agctttacga gttgtgttgc catgtatcgc
      481 attttctgca gccacttcac ccatacggta agcagcgtga gcaagcattt tcgttccgtt
      541 aacgtcacct ggcgcataga tacctggaat tgatgtctct tggtagtcat taactttgat
      601 acggttacga tccatttcaa ggttaagatt ttccagaccg ttcatttgtg gtacacgacc
      661 gatagaaaga agagcttttt cagcgacaac ttcttcacca ttgttaagtt tcaaggtcaa
      721 ttggttattt gcttcaacaa tttcagagac accaacagat gttttgatct tcatgccttt
      781 cttagaaaga attttttgaa gttcaagaga gacttcttta tccatagctg ggataatacg
      841 gtcagccatt tcaataacgg taacatccac accgtaagat gcccaaacaa gtccaagctc
      901 gataccaaca acaccaccgc ccataactgc tagtgatttt ggcatttcac gaaggtcaag
      961 gatatcatct gacgttaaga caagtttaga gtcaatacct gggatattga tacgtgatac
     1021 tttagaacct gtagcaagga taacgttgcg acccttaatg gtttgtgacc caatgtttac
     1081 agtcttgtca gggttgactt gaccaagccc attaaagata gtgactttat tagcttttag
     1141 aagaccttga acaccacctg ttaaggtttt aacaacggtg tttttaaagt caactgtttt
     1201 gtccatgtca atggtatagt tagttgaggc aaggttaatc ccacgtcctg ctgcaatctt
     1261 aataccatca aggatttcag catttttaag gtaagttttg gttgggatac accctacgtt
     1321 caagcaagtt ccaccaaatt cagatttctc aacgatggca attttaccac caagttgagc
     1381 accacgaata gctgcataat aaccagcagg gccaccacca acaacgatga tgtcatactc
     1441 atcatcagca agtgcagctt ttggtgcagc tgaagcagct tgagctggtg cttttggcac
     1501 ttcaagtccg gcagcttcta aatcttctgt tgtacgagca acattcacat ctgaagcagc
     1561 tgggctagaa acctcaacag attcaccttc agcaccgata tagccgataa cttctgttac
     1621 aggtactgtt tcacctgctt gacgtgtaat tttaagaaga acacctgagt cttctgcttc
     1681 aagttccata ttggttttat ctgacatgat ttcaagaaga atatcgcctt cattgacagt
     1741 atcaccttct tgttttttcc actcgatgat ttcaccttct tgcatgtcaa caccgagttt
     1801 tggcataata atttcaacag ccataatgta agataccaag agcaaggaga aagcgattga
     1861 atttttgcgg taagtcagaa atctttgatt tcgttgacgc acccacgtca ggacgactag
     1921 gactttccga aacaaaaatt gaagaaagtt cagacgtcta cgatgctaag attagccaac
     1981 tcttaccatt tttatccgag cttttcgctc gggttcaatt gcttatcact catttgcatg
     2041 agatctcctc gttctacatc ctttctatat ttttgagaaa agggcaccca ccaagtctaa
     2101 acttagcaaa atccctttta ttattgaatg cttttcttgt ttaaaactga ttgatcagat
     2161 taacaattca aatggatttt ccatcaattt cttgagatca accatgaatt ttgcaccgtt
     2221 cataccatca actaaacggt ggtcgatggt taggcacatt gccataattg gacgggcaac
     2281 aatctcacca tccacaaccg ttggagttgg gatagttgct ccaacaccaa gaattgctga
     2341 gtttggttgg ttaataattg ggttaaatgt cttcgtacca aacattccca agtttgtgat
     2401 agagaaggtt gatccagaca tttcagctgc tttcaactta ccagtttgcg cttttttaat
     2461 cacatctttt gaagcaagca caaaatctga caagctcatc ttgtcagccc catggataac
     2521 aggaacgata agaccatcat caagacctac ggcaatacca aggttcacaa agcggtgcaa
     2581 ttcaatatca ttagcatcat tgatgaggga agcattcatg tactcatgct caggtttcat
     2641 caaggtttta accactgcca taccaatcaa gtctgtgaag ctgactttaa ggcctgtttt
     2701 agccatgatt gggtcaatta acttcttacg aagggcaatc atctctgtca tgtcaatatc
     2761 gtagttaagc gtaaaggtag gggcagtaag gtaagagttt gtcatacctt tagagattgc
     2821 cttacgcata gctgacattg gcttgtgttc cacaccttct ggaagatcaa caactttttc
     2881 ttctttagct gctggggctt ttgcttcagc tggtttagcc gcttcaagaa tagctatgat
     2941 gtcttctttc atgaccttac cgttaaagcc agtacctgat acggttgcca aatcaatacc
     3001 tttgtctgct gcaattttac gagcaagtgg tgaagctttc ggttgagcac ctttaaagtt
     3061 ttcaacgtct tctttatgga cacgtccttt tggtcctgtt cctggaactt ggccaaggtc
     3121 aatgcccatt tctgctgctg ccttacgtgc agctggagta gcacgaactt ttccgccatt
     3181 tccttgcgga atagctgtcg ctgccacttg aggagctgga cttgccacat tttcttttgg
     3241 agcaactgtt ggtccagcat ctgctgaagc aggaactgga atttctgttg ttttttcact
     3301 tgaagcaata gtatctactg attcaccctc tgcaccaatg taaccgataa cttcagttac
     3361 aggtacagta tcaccagctg gacggacaat tttcaatagc acacctgagt cttctgcctc
     3421 aagttccata ttggttttgt ctgacatgat ttcaagaagg atatcacctt cattgatggt
     3481 atcaccttct tgttttttcc actcgatgat ctcgccttct tgcatgtcaa cgcccagctt
     3541 tggcataata atttcaaatg ccatttctac atcctttcac gatttgataa gcgccatcaa
     3601 catccccacc ttgctacgaa aacatacgaa aggtgaggtg tcgcgacacg ggataagaca
     3661 actcagttct tctaaaaact ttcaaaatag tttttagctg agacgttact gataaacata
     3721 gcctttatca gaccacttgc cttatcttct agttgccttt gtttgccatt ttcacaatgg
     3781 cagctttgat tttctcaacg tctggtaaga tcgcttgttc aagtacacgt gcataaggta
     3841 ctggaacatc ttcacttgca agacgaacga ttggatgatc aaggtaatca aaggcttcac
     3901 tttcggtaat catggttgca atttccccaa tgaatccacc tgttttgtag gcatcgttga
     3961 caagcatcaa tttacctgtt ttcttaacag attcaataat caactcttta tcaagtggga
     4021 tgagggtacg tgggtcaaca acttcaacgt taataccatc cgctgcaact tcttcagccg
     4081 cttgaaggac acgctccaac atacgaccgt atgacacaat tgtcaaatca gttccttcac
     4141 gtttgatgtc acctttgcca agtgggatat agaagtcagg atcttggtta acttcttctt
     4201 ttttaccata aagcgctttt ggttccatga aaagaacaat gttattatca cggatagctg
     4261 attttaataa gcctttagca tcgttggcat taccaggagc aacaactttg attcctggaa
     4321 tgtgagtcaa ccatgcttca agagattgtg agtgttgcgc agcggaacca ataccagaac
     4381 ctgatgccac acggaaggtt acaggggtaa taaggcctcc accgaacatg taattatttt
     4441 tagcaccatt attcacgata gcgtccatca tgatggtaag gaaatccatg aaggtaacgt
     4501 cgacaattgg acgtagtcct gtaatagctg caccaatagc tgcaccagag atagcagctt
     4561 ctgaaattgg ggtatcttta acacgtttag gaccaaattc ttcaatcatt ccaacagaag
     4621 tcccgaagtc tcctccgtaa acccctacgt cttctcccat aaggaaaatg ttttcgtcct
     4681 tgcgcatttc ctcagtcata gcaaggttga ctgcttcacg caaagccatt aattttgttt
     4741 ctgacatcat ttttatttct ccatttatta ttcaaatacg attgcttctt actgacaagg
     4801 tgatcttagt caacccaaac gtcttcgaag gctactgaaa gttctggatc tggactgttt
     4861 tgtgcaaatt cataagcatc gtcaacttct tttttgactt gtgcttgaat agcatccaat
     4921 tcgtcatcag tggcaatgcc ttcgcttgtc agataagtac gatatttgat cattggatct
     4981 ttttctttcc actcatccac ttcttcttta gtacggtatt taccagcatc tgcagtcgag
     5041 tgaccaaacc aacggtatga ttctacctca acaatagctg ggccatttcc accacgaaca
     5101 tgttcaacgg ctttgcccat tgtttcatag acagccatca cgtcattgcc atcttcacag
     5161 tagaaaccag gaattccgta agcttctgca cgtgtgtata agtgtggtgt atttgttgca
     5221 ttattgatgc tcattgaaat tccataacgg ttgttgatga tgaagaaaat aacaggaagt
     5281 ttccatgttg cagccatatt aacagactcg tggaatgatc cttcgttagt agcgccatca
     5341 cctgagaaag caacagctat attgttagtt cctttgtatt gttgggtgag ggcagcacca
     5401 actgcaagag cgtaaccacc accaacgata ccattggtac catagtttcc tttttcaaaa
     5461 tcagccaagt gcattgagcc accacgccct ttagaaacac cagttgcttt accagcaagc
     5521 tcagccatca ttttgttaag gtccatgtct ttagcgattg attgtccatg tccacggtga
     5581 tttgaaaaaa taatgtcatc gtaagacaag tgagccaccg ctccaacatt ggctgcttct
     5641 tcaccaactg agaagtgagt catcccttgt acaaatccac gacggacgag tttattaata
     5701 cgtgaatcaa attcacgaat acgttccatt ttaaggaaca tatccaaatg ttgttcttta
     5761 gaaactgtta ccatttcggc ctccatatta tcatattacc tttttatgat aaaacttttt
     5821 ttcacaattt gcaaataatt aaatcgcttt ctaccttacc ttatttggtt ttttagaaat
     5881 gcaatagttt gtgaaattac aaacaaaact gtactaaaaa atttaaaaat actatataac
     5941 agtttcacgt tttaccgacc ttgacataaa aaaacacatc attttaaaac ctctttcaca
     6001 ccttcaaaca agtaacaaag cgataaaaat aagcttagca aaactgctaa agcttatttt
     6061 tatgattcta tttgttcagc gatggtttcc cattcttcca taagagtttc ttgttcttga
     6121 tccaattggt cccattcctt ttgccaagcg attaactgcg ccgtatcatt ggaggcatgc
     6181 atgtcttctt gaatagcacc aatgcgctct tcaatggttt caagtcttgc ttcaatctcc
     6241 tcatatcggc gggtcaagcg acgacgctct ttttgattag ctttttgtag ctgataatca
     6301 gtggcagagg cttcttttgt ttcctcaact gtctctcctg ctgctaggcg ggctagttct
     6361 tctagctctg cctttttctc aaggtaataa tcatagtcac ctaagtaaag ggttgagcca
     6421 ttttcggtaa tttccagaac cttagttgcc aaacgattaa tgaaatagcg gtcgtggctg
     6481 acaaaaagca aggtgccgtc aaagtcaatg agggcattct ctagcacttc tttactgtca
     6541 atgtctaggt ggttagtcgg ctcatccaga acaagaaaat tgttgttttc catagataac
     6601 ttcgcaagaa gcagacgggc tttttctcca cctgacagca tggccaccga ttttttgaca
     6661 tcatctccag aaaagagaaa agcccctaat cggtttctga tatcgacttc tggcgtagtt
     6721 gaaaaatcct gccataattc ttccaaaact gtgttgctag acgtcaaatg tgactgggtt
     6781 tggtcatagt aacctatttc aacattggca ccgtatttca cttctccttt gatgaaagga
     6841 atctgtccaa taacagattt aatcagagtg gatttaccaa taccatttgg accaacaata
     6901 gcaatcgcat ctaatttgtg aacgtctagg ttaataggct cagataaaac atgttggtta
     6961 taaccaatag cagctttttc aaccgtcaac accacattgc cagacggctt atctgcctgg
     7021 aaagtcatgt gagctgattt tctagcacta gtcggtttgt ctaagcgttc tattttttcc
     7081 aattgcttac gtctcgcttg agcacgtttt gtagttgaag ccctgacaat atttttttga
     7141 acaaaatctt ctaacttggc aatttctttt tgctgtttgt caaactgctt ttcttcggct
     7201 actaattttt cagcttttaa ggtcataaaa cgagaataat tgccaacgta gcgatccaag
     7261 ccatgaggag ttaaatccaa ggtcactgtt gccaccttat ccaaaaaata acggtcgtga
     7321 ctcacaatga ttagagctcc ttgataattg gccaagtagt tctctaacca ggcaatggtt
     7381 tcaatatcta agtggtttgt tggctcatca aggaccaata gttctggctt ttctaaaagc
     7441 attttagcca aggccagacg agtattttga cctcctgaca gctcagcgat agtcatctgc
     7501 cacatgctct catcaaactt aaacccattt aaaatggctt tgatgtcaga ttcatacgta
     7561 aagccgcctt gctgacgaaa atgctctgta agcagatcat aatctgtcat cagtcgggtt
     7621 aaatcttgac ctgaaacggt tgccatatcc atttccatct gacgcaggcg cttttcatcc
     7681 tgtcgtaatg cttcgaaaac cttgagcatt tcctcatata ttgtttgatc tgattcaaaa
     7741 cggctatttt gagccagata agacaaggtt aggtcttttt tagtattaac ttctccgctc
     7801 gttggggttt cttccccaac caatagcttg agtaaggttg acttaccagc tccatttggc
     7861 cctactaatg caattctgtc tctttcatca acttgcagtg atatgttttg aaaaagaaca
     7921 tctcctgaga aagagcgttc taacttgttt ccttgtaaaa taatcatact ttcattctaa
     7981 caaaaaaatg cccttttgag gacattttca gcctagtttc caaaagaaat cgaactcttt
     8041 ttaagtcgtt gattaccttc tttagcgcta acaaggaaaa tggaatgact attaccactc
     8101 ccatgacgcg tctttgcaga tggcttttgt gttaagatat caaaaatttg caccacttgc
     8161 tcagtaacta tcgagatctt attggccaaa acggaatcac tgtgattaga ataatacatc
     8221 agccctataa taataatcgt tactaataag atagtttgta aaaacccttt gataagatgc
     8281 caaaacattt tcactattag cttaggcagc cacaaaatga tcgccagtaa ttgtttcatt
     8341 tgtcacctca tgttgtacta ggaaatggtt aagataacct ttcttctttt tggtagttta
     8401 tcggtaacca ctctaacagg acttctaatt gctggttcca atagtaccac tcatgtttac
     8461 catgaccttt atgataatca atgtcaagac cttgagcctg aaaatcagca atagcttttt
     8521 cattagtggc aaaaagaaaa tcctcataac cacaccaagc ataaaatttg gtttttccat
     8581 cactttctgc caccatattt ttaaggtaat gcttgtcaag gtcagggtca tcaaattggc
     8641 caaaaacgcc ctgccaatag gctaattctc ccaggtttcc ctcaagcaag gtctcaggag
     8701 aaaaatccaa agcgcctgaa aacgatgccg cataagaaaa ccgattgctt ttgagtgccc
     8761 acttaaaggc accatagcca cccatagaga gtccagcaac aaaggttttt tctcgtttct
     8821 gggtcatatt aggaaagaaa gctgctaaga cctgcggtaa ctcttgtgac aacgcccgat
     8881 aatagttaag tccataagcc gtgtctgtat accaacctag gtctgtcgaa ggcataacga
     8941 ctatcaaatt ggtatgccgc aacaagcgtt caatagctgt tcgtttttgc caagagtttt
     9001 cattgcctcc cataccatgt aacaaatata aaacaggaat atccttatcc ccttgatctt
     9061 ttttagggat ttcagactgg tcaggataaa tcacatttac cttacgctcc attcctaaaa
     9121 ctaccgaatg gtattcaatt gcaatatttg ccattcatta cactccttta taccaaaata
     9181 atcctatcac gtaaatctac tgtatttttg ggtgaacagt ttcctggtct accagttgtt
     9241 aaaatcaaag aaggtaggca gtttttgcct aaccttccta ttttcactaa cgaacttcca
     9301 tcacaaccgg cagaatcgct gggcgccttt tggtttgttc aaataagaat ttagacaaat
     9361 catctctgac attccctttt aattcgcccc agtcaaaggt atcttttttt aagtaattgc
     9421 caacagttgt attaactaat tctgcacttt ctcttaaaat atcatgactt ttcttgacat
     9481 acacaaatcc acgcgtatta actttagcct tagaaataat gcgtttttct tttttagaaa
     9541 cagtaatagc aacaatgaaa ataccatctt ctgacaagac tttacggtct cgtaaaacga
     9601 tattacccac atcaccgata gcattaccgt caatcatgac atcactggca ggtacacctc
     9661 cttcatggag aaaaccttcg tcattaagca ccatgatatc gccacgcttc agaatatgaa
     9721 tattctctgg aaaaatacca acttcttcag ctagctttgc atgggcagct aaatcacgat
     9781 attctccttg tactggaaaa agatactggg gttttaacaa attcatcaat agttgcaaat
     9841 cacgcccatt agcatggcct gaaacgcgta agttttgagt gattaattta acagaaccac
     9901 cggccttgta aatcaagttt tcaacacgcg ccaccatagc ttctttagcc gtacttggtg
     9961 ttgttacaat ataaacaagg tctccttctt tgatttgaac ataacggtga cgtcccgctg
    10021 ccattttttg taagctatta attggctcac ccatacgacc agcttcaagg atgattaatt
    10081 catggtcttc gaatttagac atatccttag gtttaattaa aagacgctca tccgtaatca
    10141 ttaatttttc tagacgtaaa gctgttctga caatgttttc tgcatctgtt ccggttaaaa
    10201 caacacgacg cccatgggct gtggcggaat caaatacttg ctgaatccga acaagatttg
    10261 aggctactgc agctacaatg acacggccat cagcatcaga gataacactg tccatttctt
    10321 caccaacttc agattcgctg gcaatctgat cgttgcttgt cgcattgact gaatctgata
    10381 aaagagctag aaccccttct ttcccaatct cagctaaacg taacaaatcc gtctgataac
    10441 cttctcttgc tgcttgatca aatttgaagt caccggtata aacaatattt cctttatctg
    10501 ttccaataac aatacccata ctttctggga ttgaatgcgt tgttctaaag aacgaaacta
    10561 ggccatcttt aaattcaatt tcagtatcac tgtctaccac atgaaaatta ttaaatttct
    10621 tagtgctgtt attacttttc acaaatagct tagctaattc aatagtcaat tcagatccaa
    10681 atacaggagc tgatacttca gctaacaaat aaggaagggc tccaatggcg tcagcatggc
    10741 catgactcaa gaaaatccct tgtactttac ctttgttttc aattacataa tctaaattgg
    10801 ggatgactaa atctacccca agttgctcat tttcggggta cttgagccct gcgtctaaaa
    10861 taaacataga atcgttaatt tctaccaaat agaagttttt tccgtattca cggacccctc
    10921 ccaaggcaat cattttaata tcagtcatga tactccttta aatattttat tattacaaac
    10981 ggtccttaca acgtaagtcg aattactgtt atgtagctat gctactatct tctatagtat
    11041 atcatatttg aggcgttttt tctctaaata gccttgatac tttcagatta ttttcagtac
    11101 agaaatcaaa aaatcactga cttattatta gtcaatgatt tagatcgttg actaatcaaa
    11161 tagttggtaa tagtcagtaa tcgtcagttg ttctttttcc atttgattta aatctttaat
    11221 aatgtttcca tctttcatta caatcagacg attcccataa gttaatgcat cttccatatg
    11281 gtgggtaatc atcaaagctg ttaagccatc ttttgtcaca aactcatctg tcagttgcat
    11341 taaagattga ctcgtcttag ggtcaagggc agccgtatgc tcatctaata ataagagagc
    11401 tggctttttc aacgttgcca ttaataaact taaagcctgt ctttgtccac cagacaaaag
    11461 acctgctggt gtttctaaat gcttttctag gccatttcct gttcgtttaa ccaaatcctc
    11521 aaaactagct aagtgctctg ttatttttcg agaagccaag gagcgttttt ctcctctttg
    11581 acgtgcgatt aagagatttt cagccactgt catccgaggg gctgttccca ttttgggatc
    11641 ttgaaagact cgcgataggt aaagagctct tttttctgcc ggccaatgcg tcacatcctg
    11701 accaagaatc ctaatttgcc cccgtgtcaa acttagcgtt cctgcaatta cattaaaaag
    11761 ggttgatttt ccagctccat ttcctcctaa aatagttaaa aaatcatgtt catagatagt
    11821 tagtgtcaca ttgtccaata ttgttttagc atcttcaaaa ccattatcta cgtcaactgt
    11881 tgcattgatc aattcaataa tttttgtcat cgtgttaacc tcactccctt aaagtagcgc
    11941 tcttttacca ctggtatcat gaggcacagt gctaaaacaa gagcactaat taatttcaaa
    12001 taacttgtat taaaacctag cgtaataact actgaaatta aaaattgata aagaatcgag
    12061 cctattacaa tagcaatcaa acgttctaaa agagtcagtc cagttgagta tagtacttca
    12121 ccaacaatta tgctcgccaa accaataaca ataactccaa tcccttttga gacatctgca
    12181 tagccatctt gttgactcac tagagcacct gataaagcta ttaaactatt agaaaccaca
    12241 agtcccataa cttccatcca atccgtgtta ataccaaaac tcttagccat atctttattg
    12301 tctcccgtag cgatataagc ttgacctaga ttagtgtaaa ggaaatagat caaaacgcta
    12361 ataacaatca caacagttat cagacctgtt aaaaggctat ttaaatcaat tgaaaaaggt
    12421 aaacaatcct gaatacgttt atgatcatgt aaacccaagt ttgctcttcc cattaccatt
    12481 agcataatgg agttacatga cgtcatcacc aaaattccag ctaaaagtgt tggcattttt
    12541 cctttcgtat ataacagccc tgttaaaaaa cctgctaaag cacctgataa cataccaagt
    12601 aaggttgata gaaatggatt ccaccctaag ctaatagcgg tgaccgcaac agctcctcct
    12661 aaaggaaaag aaccttctgt agtcatgtca gggaagttta aaatcctaaa ggtcaggtag
    12721 attcctaatc ctaaaactcc ccatataaga ccttgtgaaa ctgatgaaat aatcatattt
    12781 ttcctcatat ttatattagc gggtaactct cgccagtata aaccctttct ttacattaat
    12841 ttttagattt gttttatact tagttcagca ccgtggctta gtcttttttc caatcacttt
    12901 aacgaaacta agacagaaaa caaaaaagtc gagaatcatg tttaaactta ctcaaaaggc
    12961 aagatttttt acgtgtctaa aatagagcat tttaaaacta aaaatgataa aaataaccgt
    13021 tacatcctca agacgattgt ctgacttggc atccaaattc atctcagtga gggtgttttt
    13081 tatggttttt tcttgacctt ttatatcaca tgtcattgta ttaattctca ataaaagaag
    13141 ctgaaggaaa atcttccctg ttaatagcaa tacctaattc tgctgctaca ttcttattaa
    13201 ttagcggttg accaatatcc acaactttga caggaacatc tacaacacgc tttcctttga
    13261 ttaattttaa cacctgatta gctgtttgaa ctcccaaatc gtactgattt tgagaaatag
    13321 ctgccaaacc acctttttca accattcgat caacgctagt gtagacagga atctttgcag
    13381 ccttactggt tgtcatgact gatgaaaatg cacttgctat agtattgtct tgggggataa
    13441 ataccgcgtc tactttacct aacataactg acatcgtggc aggaacttcg ttagtagaag
    13501 gaaccgcgta tgaaataact tgatagccct ttttgcgagc taaccgccta aactctttaa
    13561 cttgagataa ggaattatcc tcattacttg catataaaat tccaactgtt ttgacatgtg
    13621 gtgtcagctt tttcattaaa tcaattgtct gtttaacagg cactttatta gatagaccag
    13681 ttacattagc ttcaggttga tccaattgca tcactaatct agatcctact ggatcagata
    13741 ctgctgacat gacaactggg atatccttgc tggcagctgc taagccttgc gccgccgggg
    13801 ttgcgatacc aatcacgata tcacttcctg attgcactaa ttgcctactc attgtttgga
    13861 ttttactctg atccccctca gcattcataa ccttaatcac tacattttgt ttttgaggct
    13921 tctgcttttt gagttgatct tcaatacctc gcttaatatc atcaagagcc tcatgagtaa
    13981 ccaattgtaa gatgccaatt gtaatgtttt gttggttagc caaatcacgg ttttcctttg
    14041 atactccttt tgataataga gagcctatca ctattacagt taaaacaagg agggtggcta
    14101 ttaaactctt gtttttcatc tgaattcctc acatttcatg tcaatctctt taaaacgttg
    14161 atgatgagaa tacttctcaa aagaaaaagc acttagtaat gattactagg cgctcttgtg
    14221 aaatccaatg tcagcgcata gatatctttt tagaagtact ctaaaagtcg tatctatgcc
    14281 aattcataaa cacaacttat ctatgccagc tttgccaatt tgctaagtgt tgtgttttta
    14341 ccatcattga cttcctttct cgttttttta acattataac ctaaatcaaa aaaattgcaa
    14401 gctctttcgt ccatattttt agtcaagtat ttgtggtata atgaagagat tagaattcag
    14461 aaaggagaaa ccatgtcttt tgacggcttt ttcttacacc atttaaccaa cgaattaaaa
    14521 gagaacttgc tttacggtcg tatccaaaag gtcaatcaac cctttgaacg ggaacttgtc
    14581 ttaaccattc gtaaccatcg caagaattat aaattgctat tgtctgccca tcctgttttt
    14641 ggacgacttc aaattaccca agcggacttt caaaatcctc aggtacctaa tacctttacc
    14701 atgattatgc gtaaatacct ccagggtgca gtcattgagc agttagaaca gattgataat
    14761 gaccgcatta tcgaaatcaa ggtatctaat aaaaatgaaa tcggagatgc tattcaggca
    14821 accctaatca ttgaaatcat ggggaagcac agcaatatca tcttggtgga ccgtgcagaa
    14881 aataaaatca tcgaatccat taaacatgtt ggcttttcac aaaactctta ccgcaccatt
    14941 ttacctggct ctacctacat tgagccccct aaaacagctg ctgttaatcc ttttacaatt
    15001 acagatgttc ctctatttga aatcctccaa acacaagaac taacagttaa aagcttgcaa
    15061 cagcattttc aaggcttagg gcgagacacc gcaaaagaat tggccgagct tctgaccaca
    15121 gacagattaa aacggttccg tgagtttttt gctagaccta ctcaggcaaa tctgaccaca
    15181 gcttcttttg cgcctgttct tttctcagat agccatgcga cgtttgagac tttgtctgac
    15241 atgcttgacc acttttatca agacaaggct gagcgcgacc gtatcaatca gcaagccagt
    15301 gatttgattc accgtgtgca aactgaactg gacaaaaatc gcaacaaact aagtaaacaa
    15361 gaagctgaac ttttggctac ggaaaatgct gaattattcc gtcaaaaagg agaattattg
    15421 accacctacc tcagtctggt cccaaacaac caagactctg tgattttaga caattattat
    15481 acaggggaaa aaattgagat tgccttagac aaggctctga caccaaatca aaatgctcaa
    15541 cgttatttta aaaaatacca aaagctaaaa gaagctgtca aacacttatc tggactgatt
    15601 gccgatacca agcaaagtat tacttacttt gagagcgtgg actacaattt atctcaagca
    15661 agtatcgacg acatcgaaga tattcgcgaa gaattatatc aggctggctt tttgaaaagt
    15721 cgccaaagag acaaacgcca taaacgtaaa aagcctgagc agtacctggc ttcagatgga
    15781 aaaaccattc tcatggtggg acgcaataac ttgcaaaatg aagaactcac ctttaaaatg
    15841 gctaaaaaag gagaactctg gttccatgct aaggatatcc ctggaagtca tgtcatcatc
    15901 aaagacaatc ttgacccaag tgacgaggtt aaaactgatg ctgccgaact agctgcttat
    15961 tattcgaaag ctaggttatc aaatctcgtt caggtcgata tgattgaagc taaaaaatta
    16021 cacaaaccta gtggcgccaa gccaggattt gtgacttata ctggtcaaaa aaccttacgg
    16081 gttactcctg accaagccaa aattctctct atgaaattat cctgataagc aactaaaaaa
    16141 aacagctctc ctaggaaagt tatttcccct aggagaactg ttttttattc tgattgttgg
    16201 tgcttgatat ggtcaagaaa gtcttgcata ttcacatcat caggcacttg tctgaggtaa
    16261 gcggtagcca tttggatagc cttgtgaaac tggccaaact cccttaataa ataggcataa
    16321 tcctgtaaaa actctggatt ttctgccaaa tcagccgaaa tctcattata aagagccaag
    16381 gcaacttctt cttgttccaa ggcgtggtaa gcctttgcaa tggtccattt ggttaagaca
    16441 ttatcaatcg tctcacgatt aagagcaata acctcctcaa aacgctcagc atcaaaataa
    16501 agggtcacta aacgcatgag aatctcttcg tcatcaacag ctacttcctt tgcttgaagc
    16561 aggtaatttt cagcattctg cctatcgtgt aattcataag aaagctgcga tgctagtaat
    16621 aataattgac tgtcaaatgc atttttacgt aggccctgtt gaaccaagcg caaagcttct
    16681 gacgtcttat gctcttcatg aagactcaaa gcataaccat attcataacc tggataatct
    16741 ggattgatgg tttccaactg tttaaagtaa agattggctt tttgataatt ttcttggtca
    16801 tacatgaggg tcgccaattc aaaaacagtt tcatcttcgt attcaatggc cacggccttt
    16861 tccaagaatt cgatggctgc ctcaaatttc cctaagctag cataggctcg tccaatgcgt
    16921 tgataagtgg aaatacctgt caattcaagg atttgacgat tgtctaactg tgcatagtaa
    16981 tcaatagctt ctttaaaata ctgcaaggac atgtcaattt ctgccaaacc aaaaatgacc
    17041 aatggctctg ggctgatgcc cactgcttga agcaattttt cacgcgccac ctctgtcagt
    17101 ccttccatgt catagaggtc agccattcct aagagagctg acaaataatt ggggctatct
    17161 tttgaaacct tatccaaata caagaaagct tcttcaatgg cgtcgtcttc tgctgcaatc
    17221 tgagctaaat ttatattgag ttctgggtaa tcatcagcta actgcaaata aatacgcttg
    17281 gcatgtggca aaaaacctat actttctaag tattctccta aggcgattaa actatctgca
    17341 tcatcttctt ttaaagcttt ttggaaatat ttttcagcgt gcgctaggtc ttgctgatcc
    17401 aaggaagcaa tcattttttc actatttaac atggtcctta acctcctcaa tcaccaatac
    17461 ttcttcgtca tacaaaccgc taactttttt gtaccagtca aataattctt taatcacaac
    17521 tttgacagaa gcgtagattg ggatgacaag gaaaacaccc cagacaccaa acatagagcc
    17581 tgcagtcaat aacaagaaca taatggtaat aggatgaatg ctcagcttat ttcccaaaac
    17641 aagcggtgct acaaaacgcc cttcgatggt ttgctcaatc ataaagataa caagcacctt
    17701 aaccaacaca aatgggcctt gtaccatagc cataatcaca acaggtatca tggcaaggaa
    17761 acttcctaag taaggtatca tgttaagaaa gccagcaata atcccaaaag tgatggcata
    17821 tttcagtccc acaaggctaa acatgataga aaacataaag ccgacaacaa ttgcaaccgt
    17881 aacctgccct tggacatacc ctgataattg cttgttaata tctcccaaga ctcgaaccat
    17941 aggcacccgt aatttgagag gtaagacatt cacaaggcca tttttcatgt ggctactgtc
    18001 tcgtaaaaaa taaaagagaa taaagggcga aataataata gccacggtaa tccgagcaat
    18061 ggcaccagca aaattaccag cccagtcaat agcatttttt tgaaaaactt tgcgcgtaat
    18121 ccaaagcctt ttgacttgta tgggtaagca tgtcttggag ttggggcttg tagctgacta
    18181 accattcatt ttcaagaagt ttattagctt cttcattgac cttgcccacg tatttgggca
    18241 gatcctcaat aaaactggta agttgggtct gtaccatggg aacaaagcct gaaatcgccc
    18301 agacaaaaag taaggtaatc aaaccaaaaa caataaaaat agaggtggta cgattcgggc
    18361 ccaagtgatt aataaggtca actaagggtt tggtcagata atacagaatg gtcgaaataa
    18421 ccaagggcaa catgatgacc gcaaaaaaag aaatcactgg cataaataaa aaagagattt
    18481 tagtaaaaac aaaaatcgtt aaaaaggcta aaagtgttat tactaaagcc atggtagctt
    18541 gattatttaa aaaccatttg taaaataagc tatctgttct agacttttca ggtattaagg
    18601 gcattaagat agggttcctt tctttgggaa aatgataagt tttactggta acctgggtaa
    18661 atcaataaaa ggtcacagat ttatccatga gttggttgtt ttggtcatag gtaaatttgg
    18721 cagagaaaaa aggacggtct tctaaaatcc atttaaaaat gtcataatca ccttcccaag
    18781 ttggcttttc caacacttga tcgtaaggta cccattccaa ggttccttct cgtgactctt
    18841 catctgaaat gaggtctcct tcaaatcctg ttactttaaa aacataggta taccagtcat
    18901 gaccaggggt aaattctgga aaagtaatga ttcctttaaa ggccatctct gtaacagtca
    18961 aatgggtttc ctctaaaatc tcacgacggg cacactcatc tggggtctca ccagcctcga
    19021 gcttacctcc aactgaaatc cacttgcctt tgtggacatc attttctttt ttattgcggt
    19081 gtaataatag caaagaatcg ccattatcaa tgtaacaaat ggttgctaat tgagtcatct
    19141 atctctttcc tttccatctt tgtttctatt ataccaatct ctagaaaata tgctatcatt
    19201 ttatgagtca aagtgtgaat acttagtcac gctcaaaacc ttctaaagat gccttaaaaa
    19261 agtgtagata aaagcctaca atgaaaaaca tcaatttaaa ctatcaaaag aaccttgtca
    19321 tatcaacgat aattgatatg acaaggttct ttaatgtttt atttaatcac ttcttgagtt
    19381 ttagcatact tggcttctac agcatctttt tctgctttcc accatgtctc attttctgta
    19441 taccacttaa tagtttcttc caaaccttct gaaaagtttg taaattgtgg ttcccagccg
    19501 agttcttcac gtaattttgt agaatcaata gcgtaacgaa gatcgtgacc agcacggtca
    19561 gttacgtgat cataagcgtc ttttggttga cccattttct caaggataag ctcaagaact
    19621 tccttgttat ttttctcgcc gtcggcacca ataaggtatg tttcaccgat acgaccctta
    19681 gtcaaaatag cccatactcc tgtagaatga tcattagtat gaatccagtc acggacgttt
    19741 ttaccttcac cataaagttt tggtttgatt cctgccaaga tatttgtaat ttgacgtgga
    19801 atgaattttt cgatgtgttg gtatggtcca tagttatttg aacagttcga aatggtcgct
    19861 ttcacaccga aggaacgtac ccatgcctta acgataaggt cagaagctgc cttagttgat
    19921 gagtaaggtg atgatggatt gtattttgtt tcagcagtga atttttcacc tggtccttca
    19981 ccctgtcctg gaaggtcttc acgaagtgga agatctccat aaacttcatc agttgacacg
    20041 tggtggaaac ggatatcgta tttacgagct gcttcaagca aagtgtaagt tccgataaag
    20101 tttgtatgga taaatggact tggatcttcc aatgagttat cgttgtggct ctcagccgca
    20161 tagtgaacaa tagcatccgc tttggcagcc aatttatcta ccaattcagc gtcagcgata
    20221 tcaccaacaa ctaactcaac acgatcacca agaatagctt caatgttagc acggttacct
    20281 gcatatgtca atttatcaag gacagttaca tgaacatctg ggtggttatt gtagacatag
    20341 tgtacaaagt tagaaccgat gaaaccagct ccaccagtta cgataatatt tttatacata
    20401 agatataaag ggacctttcg tttccgaaaa aatctattaa aagtaataac tctaacaaag
    20461 acgttttagg cctaagaaaa catcgctttc taagatttga gtcccatgtt cagctcaaag
    20521 agagaaactg aactttcctt tcatcatttt tagttgttac ttgttacctg aagtagagaa
    20581 gaataactcc cctcatatcc acctcaaatg attaatccca atcatctgag tatgttgttt
    20641 ccctataggt cttttggttt cagtggtttg acatcactaa gaagaggatg gtttttatct
    20701 gcttcagaaa cttctgcagc tgctagattt tcccaagtaa tcccaagact tgggtcagca
    20761 tagtttacaa aagcatactt aggtttcaag tcaagagccc agtagtcatt gacaagataa
    20821 ctgtaagaga cagtctctga aagaacttga aagccattag caacccctct aggaacaaac
    20881 attccttttg aagcatcaat cactgtctgg tagacgtttc caaaagtctc tccctcacga
    20941 agatcaaccc aagctcctaa aaccttgcca tcatcagcaa ctgagatgta tttatcccaa
    21001 ggttcagcat gaagtccacg cagcacatgc tgacgtgaaa aagaaacgtt gttttgtagt
    21061 tttccttcct caaaaaaacg ttctggaaag ccaattggca acattttttc tttttggaaa
    21121 ttttctttaa accagccacg attatcccca cgaacaggaa tatcaaactc tagtaagcct
    21181 gggatttctt tgatttctcg gcaagccaat ggtttgtcaa aaaaagtttc tgtcattaag
    21241 cttctccaat caaacgaagc aagtattgcc cgtattcgtt tttctttaaa gattgcgcca
    21301 atttatggac atcttcttta ctgatataac ccatgcgata ggcaatttct tccagatttg
    21361 ccacttgagc gttttgcaag cgctgaactg tttcaatata ttgagccgct tcaagtagac
    21421 tttcatgcgt tccagtgtct agccatgcaa aaccacgccc catcaattca acggagaggt
    21481 caccacgttc caagtaagcc ttgttgacgt ctgtaatttc caactcacca cgcgcacttg
    21541 gtttaatgtt tttagcaatc tctaccacgt cattgtcata gaaataaagt ccagtcactg
    21601 caaagtggga cttaggcact tctggttttt cctcgataga gatagcattc atgttctcat
    21661 caaattccac cactccaaag cgctcagggt ctttcacttg ataaccaaaa acggtggctc
    21721 ctttttcttt ggcagctgcc ttttgaagca ttttagtgag gccattaccg tggtaaatat
    21781 tatctcctaa aatcagagca acacggtcat caccgataaa ctcctctcca ataatgaaag
    21841 cttgtgctaa accatctggg cttggttgtt ccttatagga taagctaatg ccaaattctg
    21901 acccatctcc tagcaattct tcgaaacgag gaagatcttg gggggttgaa atgattaaaa
    21961 tatctttaat ccctgccaac atcaaggttg acaatgggta ataaatcatt ggtttgtcat
    22021 aaatgggcat caactgttta gatgcggcac gggtcagtgg atacaagcgt gtccctgaac
    22081 ctcctgcaag aataatacct ttcatagtag tgctcctatt cttctatata ccctatcatt
    22141 ctatcatttt ttgaaagcag tgtcacgctt taccagtaga ccgcaaaagg taaggctcag
    22201 gggaatagtc gctaggcgtt aaaagtcctt cgtgtcctag caataattga gctaattcat
    22261 agccaatcaa aggtccaact gttaatcccg atgaccctaa accactagct gtataaaggt
    22321 tcttcaatcc tggaacctga ccataaaaag gagaataatc actggtataa gctcttattc
    22381 ctacacgaca cgttttttga gtagcttctt ttaataacgg caaataagta agagcttgca
    22441 tttcaagttt ttctaaaacc tgccaatcag gctccaaatc atagccttta tcattttcgt
    22501 gactcgcacc aacagaaatc ttaccttgat tgaaaggaat aagatctatt tcaccttctg
    22561 gcataacaac tggataattg tcgctgatga tgtgatgaac gtcataatcc aagagttgtc
    22621 ccttttgtgg tcgcacatca acctgataac ctaaaggcct caataagtca ggtaaccatg
    22681 ctcctgctgc cagaatgacc tgatcaaaat aatgaccagc aatctcatac ccacttcctt
    22741 gctgtttcag agtgactttc tgccgaataa ctggataacc actagccttg agtaacgtct
    22801 cacataaagc ggctccctcc actctagcag ctcctgaagc gtacagacag ttatcaaagc
    22861 caatcaatcc tttaaaatca ttccccagtt ctttacgatt tttaatggct aactcaccaa
    22921 taatcggtga ttctaccttt cttgctaacg ctaattcata aagatctctt agtttttctt
    22981 cctgcttttt taaaacatag atgccatttt gctgataaaa atctgttgca aaaccatctt
    23041 ctttgaggtc attgattaat tgctgataaa agtccgctcc taaacgagcc atgcggtacc
    23101 aaactttatt gcgacgcttt gaaaaccaag gactaataat accagcagct gccttagtgg
    23161 cttgtccttg accatggtca aaaatggtaa cttctttttg atcactttgt tgtaaataat
    23221 aagcggcggt tgatcctaca atccccgccc caataatggc tattttcatt cctggtatcc
    23281 ttttatctta ttttaagacc ttaacagcct ataaatggct aaatggattg gtcgaggctt
    23341 tgcttgaaat aatgctgaca tcccaaccgt tctcttcttt ccacccttgg agtttctcct
    23401 ttaatttctc cgtaaaaagc acctcaatat gatgccccgg gtcaaccgca aatagtcctt
    23461 ctgtcagcat ctcctgtgct gtatggtaat agatatcccc tgtaatataa acgtctgcgc
    23521 ctttttgcac agcatcctga taaaattcac caccacttcc gccacagata gcaatctttg
    23581 aaatcaaagg gttttcctta tcataacgga taagtcgcac ggtatctaaa tcaaacactc
    23641 ttttgacctt acttgctaac tcttctaacg cttgttcttt aactgttcca atacgaccaa
    23701 tgccaaagcc ttctttggtt tcagacaagt aagttgcttc cttgatttct agcaggtcac
    23761 aaaaccagtc atttagcccg cctggtacaa tgtcaatatt ggtatggctc acatagacag
    23821 aaatgtcatg cttgaccaaa tctagaagga tatcacgctg aggggatgaa accagatctt
    23881 taagcggttt aaagatggga gcatgcttag ttataatgag atcaacttca tttttgatgg
    23941 cttctgctac tgttgactct cggatatcta aagtaatcat aaccttacga atgtctttat
    24001 ccaatgaacc catttgaaga cctttaacgt ctccttccat agataaatca agtgggcaaa
    24061 aggcttcata ggcatcaatt aggattttag ctttcatgaa caatcacctc ttttatttgt
    24121 tgtatttttg tcaagagaag ctgacgctct tgagtttttt cttctgggat gcaggacaag
    24181 gcataagcta acttatccat ttctcgttgc cacttctctt taaaaacgac tgatttttcc
    24241 tgagaaaggt atggaccaaa acgcaattct gtcgcggata aggccttttc accatgctca
    24301 gcaacgatga tttcataata tttgtcattt tcagccatga tggtttctgc aacaatttta
    24361 aaagcgttaa ccgataacca agcccgtaaa tcatcctcac gattgttggg ctgtaaaacc
    24421 agacgttcaa tgccctgcaa tttttcctta cctgcctcta aaatatcagc aatcaaacgg
    24481 ccacccatgc cacaaatggt aatggctgtc acatcatcag cttcttcaaa ggctgcaagg
    24541 ccattggcta agcgcacctg aatatgctcg gcaaggccag actgtgtgac atttttaaga
    24601 gcagattcgt agggacccct aaccacttcg ccagcaatgg ctgctgaaat ctgattagtt
    24661 tctaccaaaa atatgggaag ataggcatga tcactgccaa catctaataa tttgacacct
    24721 tttggaacat aggccgcaac ttgggccaaa cggtttgata attgactatc catcttgatt
    24781 tctttctaaa acgtaatgat tctattatag caaaattacc tccataaaaa aagaaaacca
    24841 aaggctaggc tttcgatttt ccataagtat tttgatagta cttgcagtaa gactgaacgg
    24901 gacaaatctc acattttggt tttttggcta aacaatggta gcgtccaaag aaaatcaatc
    24961 gatggtgagt aataatccaa tctttctttg gaattttagc catcaaatct gcttcaatct
    25021 gcttgacatc ggcatctggc gatgaaatat tgagcctctt tgagactcta gccacatgag
    25081 tatcaaccgc aatagctgga acaccataaa cctctgccaa taccacattg gctgtttttc
    25141 ggccaacacc cggtaaactt tcaagttctt tgtgggtttt tggcacttga cccttaaaat
    25201 catcacgaat agcctgagca gttttaatga tatttttggc cttattttta tagagtccaa
    25261 tcgttctcag agcattttca acatcagaaa gttcagcaaa agctaagtct tctatttctg
    25321 gataagactg ccatagtcca ggagttacct tattgacggc cttatctgtc gtttgagctg
    25381 ataaaatcac cgcaatcaac aattgaaaag gtgtttccca gtctaactct cccttagcct
    25441 caggaaacat ttgaccaatg atggtcagga cttttgctaa tcttgctttt ccaattctca
    25501 tgaatcactc cataaattca tcgcagatag aaaatcatct gatatcgtca cttgagaaag
    25561 atcttcgcct tctctaacac gtctacgttc ttctacttgt cgaagattaa caataccttc
    25621 ttttcgccaa ttacgtaaga tagcctggat atatttccaa tttgttttgc cgttgaagac
    25681 agcttctttt aaagcttctc gtatcaaatc aggatctgtt ttatcatcac gaagcgtttt
    25741 ttcaagatct tctaactcaa aaggactcaa gaatcgtcct aattcacgtt caaattcatc
    25801 aactaatcgt ttgaaatggt ttggtgtttc ttgtttgtca atttcagttg ccgtttgact
    25861 gacaaacaat tgatctaact tggctaacac aggactcgca tcaaaaataa tttcaatttc
    25921 tccagtaagt tcaattgtcc gcatatctaa aagcccttga ctagtcaaag atgaaatgat
    25981 tttattaata tcagcaactg attttccaag cgcatgagca atttgactgg gtgctaagtc
    26041 atctcgcttt gtcgtatttt gaagatagaa aaactgccag accaaaaaat catctgagct
    26101 cttaaaaaga tctttgtaat gaaaaagcaa ggcacttggg ataaccaaat tacctgactt
    26161 ataatgttct aaaaaactca taatccctca atcaaaaggc taaaatcgaa tctatagcct
    26221 ttactacttt aaatccccta atcagatgct gattaatgtg cttatccagg aaactgcatt
    26281 aagactttat agtcatagtt cctaatagca tgacgaccat ttaaaccttc taattcaata
    26341 aggaaggcac aaccagctac aataccacca agtttttcaa tcatttcaat agttgctttt
    26401 accgtaccgc cagtcgctag taaatcatct acaatcaaaa cacgttgtcc aggcttaata
    26461 gcatctgcat gcatagttaa agtatcaaga ccatattctt tttcgtaatc ggcagagaca
    26521 acatctcttg gcagttttcc tggtttacga acgggagcaa aaccaattcc taactcaact
    26581 gcaacaggac aaccaatgat aaaaccacgc gcttcaggtc caacaaccat atcaatatct
    26641 ttatcacaag cgtactgtgc tatttcacga atagcatagc tatatgcttt accgtcagcc
    26701 attaaaggtg agatatctcg aaacgtaata ccagctttag ggtaatcttt gatcgatgca
    26761 atgtaatttg ttaaatccat agttaattct ttctagtggc aaattgccaa atataaaata
    26821 ctcttcatta tatcacgaaa catatttttc gtaaaataag acttctgaca ttatgtttat
    26881 ctgatacttc attcgtaact acctcaataa ctactgtcaa ctgctttact tattgatcgt
    26941 ttgatttcac caaataatca tacatctctt tcgggctagc caaagccatg atttcttgaa
    27001 atttcaccaa ttcttttaag tcttggtaaa tgtggctctc tgaaatctct cgtttttgcg
    27061 cttgggggtt aaccgtcatc agcccatcgt caatcgtcac aaaagacaac tcttcaaaaa
    27121 tttgaatcaa cttaatcagt aaaagttttt ctatgtttaa atagtgactc aactctgtca
    27181 atttatgccg taaatcaaat tcaggaaact ggtagatggt tttgtagagc ttggcaaact
    27241 gctctctgct gccaaatcct gtcaaataat aaggatattt catctgattt ttaaaataga
    27301 tggcgtcaaa atccttgtga acaaactggt tgcgccaggt tttgaaatct tcagggatgt
    27361 cattaatcag aatgactctg gcatttggat cttcttcaat agtcggaata ccttcaggaa
    27421 ctttggctgt ttttgtcctt aagtcaagaa gttgcactcc gtcaacacga gcatctacta
    27481 acatgaattg gagactcgtg ttcccattcc aatggttgac agataaggta actgctaatt
    27541 ctaaaccagt agcttgtcgg aactcttgca gttgacttcc ttgaccaaaa gccagtacgt
    27601 caaaggaagc tttgccctga ctgactttaa atttaagatg gctctggtct tgccctatgg
    27661 tacgcgcttg actaaccctt atgtccttga cataaaagac cggcttttga tgatccatcc
    27721 cataaggggc taatttatct aaactcttta aaatatcaag gctaaggtcg tccaaagaca
    27781 gtctttcatc aatagttaac gtatttttgg cagtctgatc taagccacgt tctatcacaa
    27841 actgacaaag aaagtctgaa agagcttcca agttgtcaac gggcagggtc attcctgctg
    27901 caccagcatg tcccccaaag gctgtaaata actcacgctt gccattcaag gcttcaaaaa
    27961 tattaatagc ttctaaactt ctggccgagc cttttgcaaa gccattatca atggtcaaaa
    28021 cgacgaccgt ttgtccaata gtttccatga tacgaccagc gacaatccct agaacaccag
    28081 gatgccagcc agcttgtgcc aagacttgaa caggtttttg aggatcaacc atagccatcg
    28141 cttgatcaaa aatgtcttgg actaaggctt tacgctcttc attttttttc ttaatcatca
    28201 aggcaatcgc ttgagcttct tggtcatcaa agcccgtcag tagctcaatg gctggattag
    28261 ggtcatctaa gcgccctaaa gcatttaatt gcggagcaat ctgaaagcca atggcgtctt
    28321 cattaaaatg ttccaaatca ataggagata aggacatcaa ctcctgcaag cccactcttt
    28381 cggtgtgttt gagcatggcc agaccatttt tgactaaaac acggttttca cctgtcaagc
    28441 ttaccatatc ggcaatggtt ccaatagcta ccaagtctag acagtctgtt ggtaaacttt
    28501 ctagcaaagc tgttgccaat ttaaaggcaa cgccacagcc agctaagtgt ttaaagggat
    28561 aatcagcatc aggatgctca ggatgaatga tggcaaaggc ttctggcaat tcttcaggca
    28621 ggctatgatg gtcagttaca atgacatcaa cttcctgttc ttgagcatat ctaatcgctt
    28681 catgtccggc cacgccatta tcaaccgtga taattaggga cacagcttcc tgctcaataa
    28741 aatatttata gacgctctgg ttggggccat agccatctgt aaagcggttg ggaagataaa
    28801 ccaaaggctc tgctcccatc atgtctaggg tttctttgac aatagaagcc gacgtcatgc
    28861 catcagcatc atagtcgccg taaatgagaa ttcgttcgcc ctcttcaata gcttgacgaa
    28921 ttcttggcac agcttttgcc atgtcatgta gcaagtaagg atcatgcagt tgagacaagt
    28981 ccgctgttaa aagctcatct aaggcttctt cagtccttat ccctcgctca taaatcaact
    29041 gagcggcggt ctgggttaga ccttttgtct ttgctagctt aaagaagcca tcatctggct
    29101 tcttgtcttt tattttccag ctatatttgg atttaatcat ttataattaa atacctttct
    29161 tgcaagataa tcagataatt tagggaaaag ggtgtaaaat tgatgggtca ccgctaaact
    29221 aaagggcaaa ttcaattctc gtttattttt cccgataata gaaaccaaac gcttagccac
    29281 ttgatttggt tggagagtaa atttaccaac gctttccaaa taatgtccag acgggtcagc
    29341 ttggtcaaaa aacttggtgg caatgggacc tggattcacg gtggtcacgt aaaccccttt
    29401 atccgctaat tctaagcgaa gggcattgga aaatccgata agggcaaact tggtggctga
    29461 ataaatgctc gatttggctg acgcaatcaa gcctgccatg gacacaatat taatgagatg
    29521 gccttgcccc tgctctgcca ttttctgacc aatcaagcaa gcaaagtgaa tgctcgctag
    29581 ggtgttaacc tgaaacatat cagctatttc ttgggcagaa aactcttcaa agcctttgaa
    29641 agctccatag ccagcattat taatcaagac atcaatacgg ccatagcgct ggtaaatctg
    29701 ggcgaccatt ttctcaatgg ctactggatt ggtaatatcc aactcaaggc attctttgtt
    29761 gtcaatatgc tgataacagt gttctaggcg ttctttgtta cgtcctaata aaatcaagct
    29821 gtcttccttg ggtaactgct taacaattgc ctgagccagt cctccagaag ctcccgtgat
    29881 aacaatgatt ctttgtgcca ttaaataatc acttcctcta aatcttgtac cattttaaca
    29941 ttttcaaata tagtggcggc atctttttcc atctggcgac aatcacgccc taagaagcga
    30001 gctgatacat gattgagcaa gaggcgtttt gcgcctgctt catgagcgat ttgtgctgcc
    30061 tgcatgttgg tagaatgccc gtgatttctc gcaatccgct cgtcaccctt accataggtg
    30121 gattcatgaa ccaaaacatc tgcatcttta gcgagtttaa cactggcaga cgttttgcgc
    30181 gtatcgccga taatggtgat gattttgcct tttttagggg cagaaatata atctttggca
    30241 caaatcaggc ggccgtcttc caactcaacg tcttgaccat ttttaatttt gccaaagagt
    30301 ggtccgaagg gaacacccgc tgcttttaag gcttctgcgt ctagggttcc ttctaagtct
    30361 ttttgaacta ctcgataacc catgcaaaaa atggtatgcg ccagacgctc tgcatagacc
    30421 acaaacttat ctgtttccat tattttacct aatgatttgt catcaaattc atgaaaatga
    30481 atctgataag gtacacgcgc tccagaaact tttagactag ttaacacgta agttttaatg
    30541 ccaattggtc cataaatatc aagatctgtc tgttcttcac tagcttgaaa agaccgactt
    30601 gataaaaatc ctggtaatcc aaaaatgtgg tctccatgca aatgagtaat gaaaatcttt
    30661 cttatttttc gtggcttaat cgtcgtttct aaaatttgtc tttgcgttcc ttcaccgcaa
    30721 tcaaacatcc agacttcatt gatttcgtct agtaatttca aggcaagact tgacacattg
    30781 cgctgcttgg ctggttgacc agctccagtt cctaaaaatt gtaattccat tcaatctatt
    30841 ctttctattg ggtgatgtaa atcataaatt ctcgttggtc aaaatcataa tacttttgac
    30901 cagaaaatgt ttggctaaga gcccataact cctctacatt aaacccctta agcatggtga
    30961 taccgtttgc cagacggtaa atcttcgaca agagtgtgtc atcaggcgta atgtcttcac
    31021 attctccttg ctcaaactgc ttagcctgca ttttaagctg gcctttgtct tcataaacca
    31081 tatattgtgg gaaaatttgt gttaattcaa agaagagttc gggtttctta ggctctgctt
    31141 tttcagaaaa taccaatgca acttcttggt cattttggta agcaaaacca taagcttttc
    31201 cagacaaatt gaggcgtaca aagggctttt cttcctcaaa agatggttgg tcagtaaaaa
    31261 gccccaaagc cttagaaaga ttaaaataat aatcagtcgc agcttgcggt gactgtttct
    31321 ggtagatttc agcaaagtag gcattaataa cacttggtgg tggtgtgata aaagctagtt
    31381 tttgctggtc tgtcaaactg gctaacagat ggtttaggta gttggtatcc agactagtaa
    31441 atccaccata ggtttttgct aaatcaatat aattattcat aaaaatcatc aagtctccat
    31501 tgctgttttg gggaaatgta gcccgaaata tcctctattt cttggtcaaa cgtgtagtgg
    31561 tctaaaagag caactcggtt aaaatcatac agcttgtacg ccttgtcttg atgcactttg
    31621 attctaaaag gaacaaactg gtctcgaatt tggtcaatga ttaaacgtct caagagaatt
    31681 ttgctatcct ttgaacgggc tgaaatcctg atatttggaa aagcagtagc tgtgaattgt
    31741 tctgctatat ccaccttgtt ataaatagct aaacgcggaa tattaagcat gtctagctct
    31801 tttagaaggt ttaaaaccac tttttcttgc tcactatgat tagggtcgct agcgtcaatc
    31861 acatgtaaca gcaaatccac atatttgctt tcttctaggg ttgatttaaa agcagccact
    31921 aattccgttg gcaaatcttg aataaagcct acggtgtctg ttaaggttgc ttgaaattga
    31981 ttttctaaat agagttgctt tgtagttgca tctaaggtag caaataattc attggcttca
    32041 tagtggctgt catctgtcaa caagttcata atggttgact tgccagcatt ggtgtagcca
    32101 atcaagccaa ttttaaaggt atctgatccc acccgacgat ctctaatttt ttggcggttt
    32161 ttctctacct gagttaattg gcgttcaata tcagcaatct gatgacgaat cgaacggcga
    32221 tttaactcta gttggctttc acctggtcca cggctcccaa taccacctgc ttgacgactt
    32281 aacatgatgc cctgtccaac caaacgaggt aacatatatt tcaattgggc aaggtgtact
    32341 tgtaatttgc cctcatggct tctggcacgc atggcaaaaa tatctaagat taactgcata
    32401 cggtcaatga cttttacctc taaaacagct tctagattag cattttgcct agcagtcaac
    32461 cgattgttca caataactgc atcaatctca tcagcttcca caatcgcctt aatctcatcc
    32521 agtttccctg agccgataaa ggttttgctg tcgtaacgtt ctcgtttttg gctgaaactt
    32581 gccataactt tgacgccagc tgttttggca agattagcta actcagtcat ggacatgtca
    32641 aaatgttctg ttgtctgaag ctcaactcct aaaagaatca ctctttcttg ctgacgcttt
    32701 gtctcaatca tcacctttac caatcctcca aattccgtaa attctattat aacatatctt
    32761 caacagattc tgctaatttt gcgtcatgac ttctctttct gaccaagaaa atccctgacc
    32821 ctatcatgta ctacctgtgg gtaatcagga gccgttatgg cagtgaagtt aacagccatt
    32881 cgattgcgga accaagttag ctgtcgcttg gcaaaacgtc tcgtgttttg ttttaactga
    32941 tcactagctt ctgccaaagt catttcacct acaaaatagg ggaataattc cttataacct
    33001 atgccacgac tagcctgaac agtcgggtaa tgctcatata accattttgc ttcttccaac
    33061 aagccgtttt caagcatacg atccacgcgc tgattgatac ggtcatagat gacttggcgg
    33121 tcatcattca agccgataat aagcggctca taagccgtct cggcattctc taagtcgtct
    33181 gcaaattgac ttaactctaa ggcacgaatg gcccgcctgc ggttaagctg cttaatagta
    33241 atgcttttta cttgcaaaag ctcgtacacc tcttgatcag acagctggtc taactcctgt
    33301 cgataagctt ttaccgcctc ttgatcaact tgacctccta gatgataacc ttcgagtaaa
    33361 ctttgtaagt aaagaccagt tccacctaca ataattggta atttcccacg actaacaatg
    33421 tctgaaatag ctttttgagc atcttggaca aactcgtagg ccgaataaga ctccgtcacc
    33481 tcacgaatat caattaagtg atgaaccgct gcttcttgct cttcttgagt ggccttggct
    33541 gttccaacat ccaactgtcg ataaacttgc tggctatctc ctgaaataat ttctccatta
    33601 agagccttgg ctaaactaat cccaagtgct gtttttccaa ccgctgtcgg accaacaatc
    33661 acaactattt ttatttttgt cattttcttg tctttctatt agaaaagcgt gtccaaaaac
    33721 gccttttact tgaaaattat accatttttc gttaccatat attataacat aagattaagg
    33781 accactgagg tccttcacta gaaatggaga atgatcatgg ttaagaaata tcaatttgtt
    33841 aaaggtcttg ctactggcgt cctagcaact gctgctactg ttgctggtgc tgtctttgct
    33901 gtaaaaaaaa caatcattga ccctgaagaa gaaaaagctg ctttcattga agaaaaccgc
    33961 aaaaaagctg cgcgtcgtcg tgtagctcgc taacgtgaca atggatcaat ttaaaagaga
    34021 ctagcacatt aaagtgccgg cctctttttt agtaatctcg ataactagtt agtagtaact
    34081 gtctcttgat gagccaagat gttagctgct ttacttattt tgaaatagaa atctcaggta
    34141 agccccataa acatacgtga ctaaagctgt cgccaacaat acctctccta acaaaagagc
    34201 ctgccaacct aagccttgcc aacctaaaaa agataaggtc atttttaagg aagtggcact
    34261 aatcacaaac ggaaaggtaa aagctgaaaa acctggatta aagggacgat tgagtaagcg
    34321 aggaagctgt acaaccacaa aagcatataa cagttgtgag ctgacgagaa gaaagataac
    34381 cattcctact tgtggtctag gaaaggttgc taaataagac gctgaaagta aggacagagg
    34441 ggcacaaaac gttgaaatat tgggcattac tgcttgacct agaccaatcc cataagtctt
    34501 tttggccata aaaggtaaaa tcacagcagt taagagaaga caaacccaaa aaatcacctg
    34561 tcctaataaa aactgcctac tagcaggtgc tgttaatgcc gccattgcaa ttccaacaaa
    34621 aagcacggac caggaaggaa aaacgttatc ccatgaaaaa gaaaagacaa aacgatactg
    34681 gtaataagca atcaggacaa gatttcccaa aaagaatagc caccaagtga gaaagcctaa
    34741 ccaacaccct cctgtcactt tgagaaagag tgaagacaac aacatgcctg tcataaaaaa
    34801 agttggaaaa acagaggcaa ttagaggttg tcgtaactgc attttggtat cgttaaggtt
    34861 cctaaccatg ccaacaagca agataccata gataaaaaga gctgccagaa ttcccaaata
    34921 actaaaaatc gaaacataag tagccaacaa attgccaaat gacaacgttc ctaatgccaa
    34981 tcctgacatg accaatggtg ggtttttaag gtgtttcata agtgtccttt tctgcctatt
    35041 aacagctatt tttagtgaca taatcttgtt tattttatca catttcgagc atttttgaca
    35101 ccacccgcga aagaaaattt aaggctctta ccattgtttt tttacatcct cgcaaaacta
    35161 ggcaactgct taaaaagcta aggagtgacc actcttctct agaaaaaaga aagagtagag
    35221 aagacttggt ctgatcttta cttcttcttt ttgatttagt gagctgcatt aagcacttgt
    35281 tgaacagctg aatcttccac catttttgcc ataaaggctg ccagatgcgg ataattctcg
    35341 taagattttg gtgttttttg agaccatagc gccatggcgt aagcataagc atctgcaatg
    35401 gtttgttgat ctcgataaac atgcccactc tccccaataa gaccatctaa atgcgtcata
    35461 gcaatatcca tccgcttgta agaagcttgt ttgacttttt caagcgcttg attgtcttga
    35521 gaaatagtgt agcgatgagg gttgaacatt ggcctaaaaa caaggggaaa atcacctgtt
    35581 aagaagtcca tgatttcgtt gaatcgactt tctgccaaaa gattatcttg aggaatgagc
    35641 tgagatttca gggtttgttt cgctataaag ggcaagataa tacctgcctg tgtgacaatt
    35701 tgaccatcat caagctgtaa agcttaaacc attcccaaag gattgatggt aaggcagtct
    35761 tcagaatcca gttttacctt ctctacctcg taatacagaa actcacaatt cttttgaaaa
    35821 ggttctagac aaagttggtg ttgacgtctt cgctgttgat ggctctgcat gacaaaatga
    35881 gcttggtgtc cacgttcact ggtatctcgt tgcaaagtct ttgcaatttg gtctcatcat
    35941 ctgtatcaca aaaaacaaac cagtttcctg atttgttttg agatattagg cacctacaaa
    36001 ttctggcaag gattctccaa tagcttctaa acgttctgcc cattcttgac gtgataaacc
    36061 attttcttgc acatagcgat tacgttcatg tgcacgacat tcaggcgagc atcctcgaac
    36121 atactttgtt tcgttttctt ctgaagcaaa aatttgtttg ttacaaaacg gatttgcaca
    36181 attgacataa cgttcacaag gtgttccatc aaaataatct ttactaatga cagttggatt
    36241 aacatgatta attggcaccg agatacgatc atcaaaaaca tacatcgcac catcccaaag
    36301 ttcaccttga acttccggat cttttccata tgttgcaata ccaccgtgta attgtccaac
    36361 atctttaaag ccttctcgaa ccatccaacc cgagaatttc tcacagcgaa caccacccgt
    36421 acagtacaca acaacacgtt tttccataaa cttatctttg ttgtcacgta cccattgtgg
    36481 taactcacgg aaattgcgaa tatcaggacg aattgctcca cggaagtgac ctaagtcata
    36541 ctcataatca ttacgtgtat ctaaaacaac agtatcttca tcaagcaagg cttctttaaa
    36601 ttgtttagga tttaaatact tacctgttgt ttccaaagga ttaatatcac tatcaaagtt
    36661 attgtcttct aacccaaggt gcacgatctc tttcttataa cgaacaaaca ttttacggaa
    36721 agcttgttga ttttcctcgt caatcttgaa ccaaagatca gcaaaacgct catcgctgtg
    36781 gacccaatcc atatacttct gagttgtttc ataatctcca gaaacagttc cattaatccc
    36841 ctcatccgca atcaaaatac gacctttaag tccaatagat ttacaaaatt ctagatgttt
    36901 cgcagcgtac tcttgcgcat tttcaattga aacatattta taatagagta aaactctgat
    36961 tttttctgac attttttctc cttcattgtt attcagttac ttcctattat atctaggaaa
    37021 aacaagtcta ggcaagtcat ttgtttgtct tttttttcac aaaatagatc tcaatttatt
    37081 tttgatgaga tgagatgcaa cccattactc ctttaagcaa atcattagaa gctttattta
    37141 gaaaatgcta agataaaaca aggaggccaa aatgacttat gaactttgtt tagaatatgg
    37201 gacttatccg ttgtcacgtg ttgatgctta ttggggagaa gatcaaaatc ccccaacatt
    37261 cattcaagaa gatcgactgc tttgccataa attagaaact atgaatcacc tgttccatga
    37321 tttatttgta actattgaat cacaattcca ttatgttggt tttaacatgc ctgaaaaaag
    37381 agcgcagatt cggatactat atcaagaagt agctactata ttaaaatcca aatataagga
    37441 ttatccaatt aagattgaga cgtttcttct ttaaaaatct aatactaaaa aactaactgt
    37501 gcttagacag atgacacagc tagtttctta ggtaaaactc ttcttaaatt ttaaaacgtt
    37561 tcgaaaaatc actaaatgct ttaatagcac ttgctaaaaa tggtttcacc gtctcatcaa
    37621 taattaacct tgattactta caatcttatg aatctgagtc aaataaaatt caggctgtgg
    37681 cattacagag atatttaaaa cctatactca tcgttttcaa ggtcagaaaa ataatgattt
    37741 tgaaaaggtt cgtcaactct tctagataat tttggacaaa ttttggaaaa gaaacaaaaa
    37801 agccttataa aaaggtaatt atcttatttg tcaatccacc ttgaggaaat aattgttgtg
    37861 caaacggaaa aaaactatca ataaacaatt gtatttataa gctatttcaa atagtatcat
    37921 tgtatttttt tctaatattt tttggacttt ttacaacaaa gacactaatt ttattgtttg
    37981 ttatctaatt cctttaaaac tttttatgta tccatcttca attgtttgct tagattcgtc
    38041 gcatgttggc atcttcgttc ctgcctatct tatccttcgt aaaaaggtaa aaccaactat
    38101 tgctttttta ctattttata aaaatattaa tatgagttat atattacttt aaaaatatat
    38161 tattttctgt tatttatagt tgtctatttt acattattag cgatattgat gaattgaaat
    38221 aactttttta aatatagaga ggagaaccca gatataaaat ggagaaaata ttaatgaaaa
    38281 acaataaaaa agtactgaaa aagatagtat attttgtttt agcaatattc cttgggctaa
    38341 caacctcaca agaagtattt gctcaacaag accccaaccc aagccaactt cacagatcta
    38401 gtttagttaa aaaccttcaa aatatatatt ttctttatga gggtgatcct gtcgttcatg
    38461 agaatgtaaa atctgttgat caacttttat ctcatgactt gatatataat gtttcaggac
    38521 taaattatga taagttaaaa accgaactca agaaccgaga gatgtcaacc ttatttaaga
    38581 ataaaaacgt tgacatttac ggtgtagaat attactatca ctgttactta tgtagaaatg
    38641 caaaaagaag agcgtgtatt tatggagggg taacaaatca tgaagggaat catttagaaa
    38701 ttcctaaaaa tatacttgtt aaagtatcaa ttgatggtat ccaaagtcta tcatttgata
    38761 ttgaaacaag taaaaaaatg gtaactgctc aagaattaga ctataaagtt agaaaacacc
    38821 ttacagataa caagcaacta tatactaatg gaccatctaa atacgaaact ggatatataa
    38881 agttcatatc taaggataaa gaaacctttt ggtttgattt ttttcctgaa ccagaattta
    38941 atcaagttaa gtatcttatg atatataaag ataatgagac gcttgactca agcacaagtc
    39001 aaattgaagt ctacctaaca acgaagtaac tttttgcttt ggttcaatct ctcctactgg
    39061 tggatttaga aattttattg caattatctt attattgtaa aaaccgctca gcttaatgat
    39121 ctgccttccg tcaagtagac cgattaaata tctaaaaaca gtgtctgttt gataaaatca
    39181 gtcgcacatt ttgtacgact gattttttta tacatatcac ttagatttgt acttttcaat
    39241 tcgtttattc ttagccatag gataggacgt aggatgttct gaatttaagg caacgtttcg
    39301 tacttccgaa gtgttttgca gtcatatctg ctctatggac gctcatgact gtaaaatcgg
    39361 atatagtctt tgatagcatg tcggaaaaag ttcttatcag aaatctcata catctgatac
    39421 atttctgatt ttatagttcc ccaaaaattt ctactggtcc gttatcaata caatgaccta
    39481 ctcttgacat ggatcgaatt atatcattat ctttaatctt ttttaaaagt atttattggt
    39541 atattgaaat cctctatcac tgtgaaatat agacttcgct gtgggacttg ccttaatgac
    39601 cttgtcaaat gctttgaaga ctagccgatc atcatttcga ccacttataa cgaaagcaac
    39661 aggaggagca tcaagtatgg cactaagata gagcttatta tgagagctag gaatcttaaa
    39721 ccctgtgaca tccgtgcccc atttttcatt tgaattagtt acatagaagt ttcttgccaa
    39781 cttattttca gcgatttctt caggcttagc agtcttgtat ttttttctta catataaaat
    39841 agtttttcta aaaataatct ttttactact aatttttatt acctacacta cttttttgag
    39901 gagtactcta ccctataatg ttaacaactt ctagtaaatt ttaaaaaaca taaaaacacg
    39961 aatatcataa atttatgtat atactattaa ctagtaaact tcaagaaaat ttaagtaacc
    40021 aattgaatta tcaacatgaa actgagttga agctactctt tcattattgg aatatatttt
    40081 tagtacacta ttaaagtctc cattgcaaaa ataatacaaa tcaaaaacaa tatatttacc
    40141 tgaatttaaa tctaaagtaa cagttccttt agggtatttt ttgttctcga ttattataaa
    40201 tattatattt cctaatcaac aaatttctaa cttttatctc cacttcctga gcggttactt
    40261 gcggtttatt gattgtaatg aacataggcg gatgttgttt atttttgtcg cacacgttaa
    40321 tagaaacttt agtttctttt tttctgaatt ggttaatgta actccaccaa atgcttcata
    40381 tctttttccg agacatacac agatctcttg tgcggataaa gcataaatat ctacttcttc
    40441 atctttaaat ttccttgata tccaatcttt tacaaaaaaa caaacaaatt tttattctta
    40501 agactatatt ttaacatatg aatagtaaaa acatctgaag aattttttat attattaact
    40561 tcaattaaat tagaatcact accattaaag cgactatata ttatgtctgt tattagcatc
    40621 acatggatta gcgtgagcaa cattggaata taaaagaaat gccaaccatg taatggtagc
    40681 aaagactttc ttatcaacat ttgggcagcg aaaagtatat ctcatttttt tccttaaaat
    40741 tcagagtttc atttattaaa ttcaactaag tctatatcaa tataaagctg atcagataag
    40801 cccactgtac tttttagtat actctctctg tcgccaaatt ctgtgtcaaa aagattataa
    40861 gaaattttct ctccgctatt caaatgaaaa acaatatttc cttcctcaag tccagattta
    40921 aacctagagg agcgaccaaa atttttaaca tcactgaatc cgcatatatt aaaatgtttt
    40981 tgaaggtaat atcttgattt cacatcaaat tcttgaatag cgacttcttt cttatcagta
    41041 ctcacagtac ttatatctgt atagttatat ttttttaatg tcgtctatga aaatattaac
    41101 aggtatattt ttttatcaat cctattacca tccaatcggt aaattcacca tataccaaat
    41161 catgctcctt gacgtgattc aatcgtctat caatttccca aatggagtga cctttgatat
    41221 ttttatgatg attgatttct aattcaattt attgctagtt atttaataat gttatttctt
    41281 gcatgttgtc ctttctaatg ttgtataatg tagctttccc attagacagg aggtgaacta
    41341 aagataacta aatgggaatt attatttcaa aaaatttctc tttagcagtt gtcgcttcat
    41401 caagttctga tctatcaatt gaagataaaa tcaaacttta tgaagataca attattgcta
    41461 tagaagctct caataaacca ttaattgacg ctaaaaacaa gaaaataact gacaatttta
    41521 agttattgga gaaatctata ttagtggcga atcatttttt tgttcataat atctcttcta
    41581 gtattgtagt tgatttcatc tcattttgag atatttgtat ttaaaaaata acccactctc
    41641 tgaaacgtta aatttttgag aaatgatagc catttcataa tctttaaaag gctgtaaacc
    41701 gtcttctttc tcagagtaac cttttctatt ttttaaatca attaagtcag ccatatacat
    41761 ttctgtgtat tcacgtttta aacgtttttc ttttaaacgc ttcttaggtt tgagatgttc
    41821 ctgttttaag cgttgctttt tcgtcattcc tccacccact ttctgtggta taatttaaat
    41881 aaaaagtttg gagagagtat atatgaatac aacagtaagt actatacttg taagtttagg
    41941 aacaaactta gcaaccgacg ctgtccaaaa agctaacaat cctgcaagag ctattgacga
    42001 tttaatgacc ttgataggtt ttgaaaaaat tcatgcttgg gcggaaaaag cccgaataaa
    42061 acacgctgct gacttagatg actttaagca taaactcgct gaggaaattc ttcaaatagc
    42121 tactgacaag ctaaaagacc ctagcttgaa tattctcggt cctgctctcg aagcatcaaa
    42181 ataccatatt gaacaagaaa caattagaaa catgtttgct cgattgattg cttctgatat
    42241 cgattcatcg aaagaaaatt tagtccaccc atctttcgtg gaaatcatca agcagctcag
    42301 tccactagat gctcaaaatc tatcaattat ttttaactat aaatacacgg acatacctgt
    42361 tgcaaactac tatcttactt ataaaaatgg cagagggatg aaactggcac atcctgacgt
    42421 ttttctttta aacccagagc aaaatatgtt agactataat tcgtcgtcct tagaaaatct
    42481 tagaagaatg ggaattattg agatcctata caaccagtcc aaacatgacg aacatcagta
    42541 ctcactttta agaaacaata attatttaga tgatatcgct aagcatactc aaagcaacga
    42601 cccaaatttt caagacatct atgtccaacc cggaattact cggttaacgt atttcggtca
    42661 agatttctgt gaaacttgct tacctccgaa atgattgttt aatatggtct gcgaaatctt
    42721 cgaatttgtg acttgagaaa tttttcttct ttctcaaaga aatcatcaat ccatttttta
    42781 aaccaataaa tgctaacctt tagcataaat aatgatacaa cgaaagatac gaatgctgaa
    42841 acaaaaacat tagtcatgta ttttcctttc cactcccttc tcgggagttt ttgttttgct
    42901 taattccttc atcttgatta tagtatacta cactttaagt gtacttgaaa gtgttttttt
    42961 gcattttgct aaaaaatatt gtatttattc cacttgaagt gtacaatatt gttagacata
    43021 taatagtaaa ggagcaaaag atggctaact tatcggataa tatcaaatat ttcagaaaac
    43081 aaaataagct aacccaaaaa gagctagcta aaaagctaaa aatagctcca acagccattt
    43141 cagcttggga ggtgggcaga aacaaacctc taatggataa tatagaacaa atgacttcta
    43201 ttttcggaat accaaaatcg aagcttttag gtgacgaaat atataaaatt caagaaactg
    43261 cctcaccaga actcattcca tcaaccctac aaaagataac cgcaacatca tcacaattag
    43321 aacacagcag acagctaatc gttctggata cagctgaaac tttgctaaat caacaaaaag
    43381 aaattaaaaa taatgaagat acagtagtag aattattttc ttacaattat tacgaccaac
    43441 cagcttctgc tggtactggt cagtatctaa atgacgtaca agtggaaaca attgagctac
    43501 cagtcgatta tgacgctgat tttgttatcc ctgtctacgg tgattccatg gggccagaat
    43561 accactctga ggactatgtg tttgtgaagt tatctgtaga cctctcagat ggcgatatcg
    43621 gcgtgtttga gtattacgga gacgcttata tcaaacaact gcttataaac gctgagggag
    43681 cctttctgca tagttttaac agcaaatatg atgacatacc gatagataga gatagcgact
    43741 tccgcattat cggagaagtt attggtagtt attcggaaaa ataagcacca ttgctaaaga
    43801 tgaattttat aatttagcga atattatgta gagagagggc accatgaaag aattacaact
    43861 gacaaacatc gaagctcagc aactcataac cttattaaag gtcattgcaa cccagcacaa
    43921 taaaacatta acaaataata caagtggtca tattgatatc gtaggccaaa accacaaaag
    43981 atttatttta aattatttct atagcacgaa tagtaaggtt tttcatctca gagaaacaga
    44041 acataattac actcttatcc gtatcaatct aaataataaa ttccataaaa attccaatgg
    44101 agaaaaaatc tggggaaatc gtattaatat cttttcggaa gaagagtatt atctaaaagc
    44161 agatgaaagc acccattaca aagcttatcc tttaccatac gaaaccatca aagatacaaa
    44221 tgattttcta gaaatgatgt ccaacttatt tgattacaca aatatcaata atcctcaaga
    44281 tgctaatatc aatatccaag aagatttgat ataataaaac cactaagaaa ggagtcacca
    44341 tgaaggctag tgatgtaaaa aaagaatatt tagcatttgt aaaagaaaat acgattttta
    44401 ataatgcaac tgagacacac actgaagttg tgacaccttt tgtagatcca ttcggtgagg
    44461 ccattggatt ttctatcaaa tccaacggaa aatcattgac catcaccgat gatagttata
    44521 ccatttggaa tctttctatc aacggtattg atgttacaaa aaaagggcgc agaaacgatt
    44581 tgttcctctc cctactacac tataatggtt ttgatttagt ggataaagct attgaaagga
    44641 cagttgcgaa agcaaacctt ggtcaagcta tacatgatat gactcagttg ttaatgaatg
    44701 tatatgattt tatccaactg agcccaaata atgtaaaatc tcaatttcta gatgatgtga
    44761 agagctactt catgtcagac aatcattact cagtattccc agcattctct atcgcaggac
    44821 gctctagatt agaacaccgc tttaattttg tattcatgag tcatggaatt tctaaaatag
    44881 ctcgtgttca taatcatgtt accaaacaac aagttgatac cattctagca agttggcttg
    44941 atacatcgga attccgaaaa agagaatatg gagacaaaga agaactctat attattgtga
    45001 gcgatgacgg attcaaaaac atgaaagatg accacctaat cgctctccaa gaatataata
    45061 ttcatatctt aaattttgct gataaacaac aacttcaaat gcagctaggt aaatagatta
    45121 tcataaaaat tttgtaaata tcctatcaaa gtataagaag tttagaaaca aaaaaagccc
    45181 cacgcttttg tactgacccc caaaagttgg acattatatt ttaagcaaag gatttagttc
    45241 tgtattgtac aggactaagt ccttttagtt ttactttgat ccgtttattg ttgtaataat
    45301 aaatataatt agtaatagcc tgttctacat ctcctagaga tttatagttg ctctcatacc
    45361 catagaacat ttctgacttc aatatgccaa agaaggattc catcatcccg ttgtcaggac
    45421 tgtttccctt acgtgacatc gatggacgga tacctttaga gtttaaaaat tggtgataag
    45481 aattatgctg atactgccag ccctgatcac tatgtaatat agttccatca tagtatttat
    45541 ctggaaatat tctttctagc attgtattaa tttgatttaa atcaggagaa cgtgaaatgg
    45601 tatagtttat tatctcgcta ttataaccat caagaactgg tgataaatag agttttccct
    45661 caggtaaagc aaattccgtt acatcggtgt aacacttctc atagggttta gaagcttcaa
    45721 attgacgttg tataaggtta tcagctttct ttcctatttc acccttatat gatgaatagc
    45781 gtcttttgcg acgtatttta gctgccaaac ctaattcttt catcaagcgc tgaactcttt
    45841 tgtggttgat gttagatcct ctgttacgca gttccatagt gattcgacga tagccatagt
    45901 tccctctatg ttcttgatag attgcttgaa tttggtcctt aataggtttt tctttatcac
    45961 ctaatttaag ctgtctaaga tgataatagt aggtagaacg agataattta gctgctctta
    46021 gaagaaaatc taatcggaag tcgtcttggt ccattcttcc aattgtttct accttcttct
    46081 ttgcagagct tcttccttca aacggagtcc ccccgacccc cggctttttt aagtaagcaa
    46141 cctcagttct aagatactca ttttcttctc gaagtcgttc taattcagtc atttcttcgg
    46201 gcttcttttt gggtttacgt cccatttgtg atggtctccc tcttgttttc tcaacaatag
    46261 tataaccgtt tttcttgtat tatgctatcc aattggcaag agttcctgga tttgggaagg
    46321 cgtaatctag agaaactgag aataaggatt gcccatcttt caagacttta ttaatcattt
    46381 cttgcttcat ttcagatgaa taagcttggt acttttgctt cttaacgatc tcgactccat
    46441 aacgatccat cagtcgaaca gtatatctca aattactagg gtttactcca aattgattcg
    46501 ctagctcagg ccaactaaga cctgacttcc ttaaacgata tatttctaat ttatcttgat
    46561 aacttaattt catacaaaaa caccccaaat gttagatttt tttgtctaac ttttggggtg
    46621 tagttcaata aggctttttt atatgatttc tatccacctt gagggaatcg aacccccatc
    46681 tcaagaaccg gaatcttacg tgatatccat tacactaaag gtggtcacaa ctttatcaat
    46741 acccttatag tatatcataa aatgaaataa tatgaaataa cttttctaac cagaagacaa
    46801 taaaaagttg aggaaaacct caacttttta gatttattac aattcaatat caccgaaaag
    46861 atcagccatt gagaatccag tttgtgtttc tgggagttcg tagtcacgtc ttgattcacg
    46921 ttttggacga cgtgggcgtg attgacgttt ttcttctttg ttgtctcctt cagcttgcgc
    46981 tgggcgttct tcaagagctt tgattgataa tgatacgcgc tcatcagctg cattcacttc
    47041 aagaacttta actgttactt cttgtcctac agaaagtaca tcttttggat tttcaacacg
    47101 tttgtgtgaa atttgtgaaa tatgaacaag tccatcaata cctggtaata cttcaacaaa
    47161 agcaccgaag tcagtcaagc gttttacttt accttcaaca acatcacctt gagcaagttt
    47221 ttgttcaacg ccgtcccatg gtccaggtgt tgttgcttta agtgaaagtg acacacgacc
    47281 agcttcttcg tcaattgaaa gaactttaac ttcaacttct tcaccaactg aaacaactga
    47341 tttaggtgac acgttacgtt cgtgagacaa ttcagtcacg tgaacaagtc cgtcaacacc
    47401 accaaggtca atgaaagcac caaaacttgt taaacgcgct acagtacctg taacgactgc
    47461 accttctgaa atcttagaga acacttcagc acgagcttct ttagcggcct cttcgataac
    47521 ttcacgacgt gataggatga aacggttttc tgctgcatca acttctttga ttttagcatc
    47581 aaactcttgt ccaacaaatt tttcagtgtt gcgaacaaaa cgagtgtcaa tcattgaagc
    47641 agggataaat ccacgaagtc cttcaaattc aactgaaagg ccacctttaa cagcacgggt
    47701 acctttaaca gtaacaactt cgccttcacg accaacaagt ttgtcccagg ctttacgagc
    47761 ttccaaacgt tttttagata ctaggaaagt aactgtatca gtatctttac ctactacttg
    47821 acgaagaaca agtacttcaa ctgtgtcgcc agctttaaca aagtcgttaa tatcagcatc
    47881 gcggtcgtta gtcaattcac gaagtgtcaa gacaccttca acacctgttc cttcgataac
    47941 aacgtttgct tgaccgttat caacagttaa aacttccgca gtgacaacat caccagggtt
    48001 cacttcgcta acactgttta gcaaatcttc aaattcattc attctaaaaa atcctccaac
    48061 aaaagctagc caatgctagc ttttgataac aatatatttt ctcaaggtaa cccgcaacga
    48121 caacaactct tatctttgac ggtctcaggg agcacctgat acctctgact ggggtagctg
    48181 gattcgaacc aacgcatgag ggagtcaaag tcccttgcct taccgcttgg ctatacccca
    48241 aaaatatttt ttacagaaaa ctaattttct aattagatta gtttccgaaa tggaaagaga
    48301 gggattcgaa cccccgaacc cgaaggagcg gatttacagt ccgccgcgtt tagcctcttc
    48361 gctatctttc cgtaacaaca aaaactattc tatcatagtt tttgtaagct ggcaagtgtt
    48421 tttgtttaat tttaatggtt caaattgtag ttttcaatga tattttcaac cgcttgttcg
    48481 agcgttttga agaagcaatc tactccatca ttttttaaga cagcaaattt ctcatcaagt
    48541 tctgcaattt ctccaaccac acgtttacca atttgtaatt gatagccatc aatcttagtc
    48601 tcattaacca taactttgta atcaatcagt tggatttcaa tttttttatc ttttttactc
    48661 atcactttac ctcactttgt ctattttaca caaaatcaaa aaagcttgca agagcaagct
    48721 ctattttaat ctacttttac aatccaacct tctggtgctt caatatcccc aaattgaatg
    48781 ccgaccaact catcgtataa acggcgtgtc acaggaccaa cttctgtttc actgtaaaag
    48841 acatgtaagt tatccttgta ctggataccg ccaattggag agataacagc tgctgttcca
    48901 caagctcctg cttccacaaa tttatccaat tcattaattg gaacatcacc ctcaattact
    48961 gtcataccaa gtctttcttc agctagttgt aagagtgaat acttcgtaat agatggcaag
    49021 atggatggac taagtggcgt aacaaattca ttatttgcag taatgccaaa aaagtttgca
    49081 gctccgactt cttcaatttt agtatgggtt gctggatcta agtaaatcac atcagaaaag
    49141 cctgctgatt tagcggcctt acctggtagc aaacttcctg catagtttcc tcccacctta
    49201 gcagcacctg ttccgtaagg agcggcgcgg tcaaacgctt cagaaacaat aaaattagtt
    49261 ggagcaagtc cacctttgaa atagtttcct actggcatgg caaaaatagt gaaaatatat
    49321 tcttcggctg gtttaatccc aataatatct ccaactccaa ttaataacgg tctcaggtaa
    49381 agcgttgcac ctgttccgta aggtggtaca aagtcttcat tggctttaac cacttgctta
    49441 gctgcatcaa taaattgctc tgttgatact tgtggcatca acaagcggtc tgctgtggct
    49501 tgtaaacgcg ctgcattacg gtctggtcta aatagttgaa tagagccatc tttggtgcga
    49561 taagccttta aaccttcaaa agcttgttgt ccataatgaa gcgctggagc gctttctgag
    49621 atatgtaagg tggcatcttc tgttaattga cctttatccc attgaccatt tttgtaataa
    49681 gaaatgtaac gaaatggcaa cttatgatat tcaaatccta ggttgtccca atcaattgct
    49741 attgtcatca tcgtacctct tttctacttt tttctattgt aacttttttt caataatttt
    49801 caagtttatt ctattctttt gcattaatat tctaaattta ccataaaatt aaaaagagtt
    49861 ttcactcttt ttaacgtgtt ctagctacca gtacttcttg atccgaaata gtgtctgaaa
    49921 taaaggagcc attgctggtt ctttccgata acgaaagcgt ttctaaagca atctcgtagg
    49981 tttgaccagt cttactaatg acttcaagca tttgttgatt agtttcttct tcaggtatat
    50041 cagtgaacaa atcaaactgc tcagctgaag catctgattg aacgcctccg gccagaaaaa
    50101 ctctatgagg tttggttttt aactctcgta ggaccaatag tccacgattg gcacgacttg
    50161 tctgaggaat atcatcgaca gccatccgtt tgagagaacc cctctgagtt aagacaaaga
    50221 aagagttact tgtcacagca aaggctgagg caaggctgtc atcatttttc aagttaatgc
    50281 ctttaacacc agcagatttc aacccttgaa taggcacttc ctgactggag aatcgcaaag
    50341 cataaccatt tttagtcact aataggaggt cttccataat aactggtgac aaggtaacca
    50401 cgcggtcttt gtcatccttt agcttcacat atttggttga tttagattta taagttcgcc
    50461 aaggacttag ttctttacga tcaaagcgtt tgataaaacc attttgtgtg acagccacat
    50521 acaagccctg gtcaaaggaa gtcacaatat cagcgtagag aatctcttct tctgtcgcga
    50581 agtttgaaat ggtttgtgat aaatgttcac cgatatcctt ccaacgtaaa tcggtcaatt
    50641 catggattgg ccggtaaatg acattgccta aagttgtaaa caacaaaagg tgttctgttg
    50701 ttttggcctg tttaacgaag atgagttcgt catcatctct cttgccaact tcttccaaac
    50761 tagacgcatt gaaggatcgt gggctggttc ttttgaggta tccgccccgt gtcacactaa
    50821 caaaagtttc ttcctctgca atcaagctgg cagtgtcaat ctcaatgatt tgactttctg
    50881 cttgtaactc tgataaacga ggattggcga atttcttttt cacttctctt aattcacgtt
    50941 tcatgacgtt atacatggtt gcttcgtcac cgataatagc ggaaagggtc gtgattaagt
    51001 ctcttaaatc attttcttca ttttggagag taacaatatc ggtattagtt aaacgataaa
    51061 gctgcaaggt tacaatcgct tctgcttgtt cctcagagaa atcatagctg actttcagat
    51121 tttctttagc atcagcctta ttgtcagacg atctaatcaa agcaataatc tcatctaaga
    51181 tggacaagac acgaatcaat ccttcaacaa tgtggaggcg tttttcagct ttggctttat
    51241 cgaatttaga ccgctcaata ataatatctt tgcggtggct gatatagctt gataagattt
    51301 tttgaagacc tacttggcgt ggcgtaaagt gatcaatagc aaccatatta aaattataat
    51361 taacttgaag atctgtgtat ttcaacaaat aatttagaat ggtttggcta tcagcctctt
    51421 ttttcaactc aatagctatg cgaagacctg tgcgatcaga ttcatcgcgt acttctacga
    51481 tgcctgggac tttattgtta acacgcacat cgtcaatctt tttgaccaag actgctttgt
    51541 taacttcata aggaatctca gtgacaataa tttgttgttt accaccttta agttcctcga
    51601 tttctgtcct agagcgaaca acgacacgtc ccttgcctgt ttcgtaggct tttttgattt
    51661 cgtcagctcc ttggataata cctcctgttg ggaaatctgg cccaggcaaa aattccatca
    51721 atttctctaa actagctttg ggatgatcaa tcatatacac aacagcatca atcacttctg
    51781 acaaattgtg cggtggaata tctgtcgcat agcctgcgga aataccagaa gacccattga
    51841 caagtaagtt aggaaaagct gctggtaaaa cggtgggttc tttttctgtg tcatcaaagt
    51901 tccacgcaaa agagaccgta tttttctcaa tgtcttgaag aagataacct gcaatttcag
    51961 acaagcgagc ttctgtataa cgcatagccg caggcggatc gccatccatt gaaccattat
    52021 ttccgtgcat ttcaacaagg atttcacggt tcttccaatc ttgactcatc cgaaccatgg
    52081 catcataaat agaggcatcc ccatgcgggt ggaaattccc cataatatta ccaactgatt
    52141 tggctgattt acggtaacct ttttcaaaag tattgccatc cttattcatc gaataaagaa
    52201 tccgacgctg aacgggtttc aatccatctc gaatatctgg aagcgcccgt tcctgaataa
    52261 tatacttgga ataacggccg aagcgttctc ccataatatc ctcaagggac atgttttgaa
    52321 tgtttgacat attcaaatag ctttcttttt cattatttat taattaccta aaaaacaatc
    52381 gtctttagca cttgtaatta tctgtgagaa acttgtatga ctaaaacacc gtattttctt
    52441 ctaaggtaaa cttgacgtta tcctcgatcc actgacggcg tggggctgct ttgtcaccca
    52501 tcaacacaga aacacgtcgc tctgctcttg ccaagtcgtc aatagtaaca cgaataaggg
    52561 ttctggtttc agggtccata gtggtttccc ataattggtt agcattcatt tcacccagtc
    52621 ctttatagcg ttgaagaata gcccccttgc caaattctct gcgcagatct tccaattcac
    52681 catcagtcca agcataagca attttttcag ttttgccttt gccttttgac attttgtaaa
    52741 gaggtggaag ggcaatgtaa acatgaccgg cttctaccaa tggtcgcatg taacggtaaa
    52801 agaaggttaa taggagggtt tgaatgtggg caccatcggt atcggcatcg gtcatgataa
    52861 taatcttatc atagttgata tcctcgaggt taaagtcagc tcccactcca gctccaatgg
    52921 tataaaccat agtgttaatt tcttcatttt tcaagatgtc agccatttta gctttttcgg
    52981 tatttaaaac tttgccacgt aatggtaaaa tagcctgaaa tttgcggtct cgtccttgtt
    53041 tggctgaacc tcccgcagaa tctccttcga ccagatacaa ttcatttttc ttggcatttt
    53101 tggactgggc tggggttaat tttcccgaca acaagccttt gtcttttttg tttttcttac
    53161 cattacgtga gtcatcacgc gcttttcgag cagcttcgcg agcatctcta gctttaatgg
    53221 ctttgcgaac tagatgagaa gttacttctc cattttcgag taaaaagaag gttaattttt
    53281 cagaaacaat gctctctaca ataggtctag ctaagggact tcccaatttg tctttggtct
    53341 gtccttcaaa ttgcaagtgc tgctcaggaa ctaagataga taatactgct gagagtcctt
    53401 ctcgataatc tgagccctct agatttttat ccttttcttt taagagattg gttttacgag
    53461 catagtcatt catcgctttg gtaatagctg actttagtcc cgtttcatgg cttccaccat
    53521 ctttggtacg cacattgttt acaaaggata agatattgtc ggagaaacca tcgttatact
    53581 gcaaagcaac ctcgacttga aagtcttggt cttgaccttc catgtaaata acaggtgtca
    53641 aggtttcctt atcttcattg aggtattcga cgaaatcttg aaccccattt tcataatgaa
    53701 actcttcaat aatcgggtca tctccacgaa gatctgtcaa gctcatcttg acatttttca
    53761 aaagaaaagc agattctttc aatcgttctg aaatggtatt gaacttaaag tcaatagttg
    53821 aaaaaatctt atcatcaggc ataaaggtta caaccgttcc tgatttagac ttaggagctg
    53881 tgccaacttt tttaagggtt gtaacaggtt tccccccatt ttcaaagcgc tgacgataca
    53941 ctgccccgtc tcttgtgatt tcgacttcta accaggcaga caaagcattg acaacaga
//
LOCUS       DAXMQE010000011        53661 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.011, whole genome shotgun sequence.
ACCESSION   DAXMQE010000011 DAXMQE010000000
VERSION     DAXMQE010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 53661)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53661)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53661
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.011"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     misc_feature    78..213
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            243..743
                     /gene="rplJ"
                     /locus_tag="ACF4ZO_000721"
     CDS             243..743
                     /gene="rplJ"
                     /locus_tag="ACF4ZO_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012658294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HFD5486284.1"
                     /translation="MSEAIIAKKAEQVELIAEKMKAAASIVVVDSRGLTVDQDTVLRR
                     SLRESGVEFKVIKNSILTRAAEKAGLDELKDVFVGPSAVAFSNEDVIAPAKVINDFTK
                     TADALEIKGGAIEGAVSSKEEIQALATLPNREGMLSMLLSVLQAPVRNVAYAVKAVAE
                     NKEGAA"
     gene            808..1173
                     /gene="rplL"
                     /locus_tag="ACF4ZO_000722"
     CDS             808..1173
                     /gene="rplL"
                     /locus_tag="ACF4ZO_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HFD5486285.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAAAAA
                     GGAEEAAKDSFDVELTSAGDKKVGVIKAVREITGLGLKEAKGLVDGAPANVKEGVAAA
                     EAEEIKAKLEEAGATITLK"
     gene            1412..2647
                     /gene="pbp3"
                     /locus_tag="ACF4ZO_000723"
     CDS             1412..2647
                     /gene="pbp3"
                     /locus_tag="ACF4ZO_000723"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase PBP3"
                     /protein_id="HFD5486286.1"
                     /translation="MIKRWAILFFVVLTCSGLSKIVLAADFQVGAEHAIVVEADSGRV
                     LYEKDAKTPDAIASLTKLVTAYLVLDKVKSGQLQLSDQVNLSDYAFELTKDRSLSNVP
                     FDKKTYSVQDLLTATLVASSNSAAIALAEKVAGSEPHFVNQMREQLSHWGITSGKILN
                     ASGLPNEVLKDHRYPGSALEEENTLSAQDVAVVTMRLLEDFPEILEITKQTEVNFAGN
                     SIKSFNQLLPGMAKGRAGVDGLKTGTTDLAGHCLVVTSIENGMRVITVILNADGSDKN
                     QNTRFEQANRLLDYVARTYCRRKILKKGSLVSERSLPIQDGQVKELPVSVAEDVTIIL
                     QQGEQVPKPKQFMISETSLLAPITKGEVVAYLTSPRITDQSVRYLKEPKRIPLKASQS
                     LKKASDLQLWWRDFLEKRR"
     gene            complement(2764..3726)
                     /locus_tag="ACF4ZO_000724"
     CDS             complement(2764..3726)
                     /locus_tag="ACF4ZO_000724"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HFD5486287.1"
                     /translation="MNNRHKRRQKRKAFTLINLILLFACILGLTLIFYLYQGSNKFGL
                     SDVSQFVPKISLFHHKKTAKKETTKLKKTHFDSSKSQKKAHSKLTWTKQETPVKIPIL
                     MYHAIHVMSPEETANANLIVNPDLFDQQLQKMKDEGYYFLSPEEVYRALSNNELPAKK
                     VVWLTFDDSMIDFYNVAYPILKKYDAKATNNVITGLTEIGSAANLTLKQMREMKQFGM
                     SFQDHTVNHPDLEQASPDVQTTEMKDSKDYLDKQLNQNTIAIAYPSGRYNDTTLQIAA
                     RLNYKLGVTTNEGIASAANGLLSLNRIRILPNMSPENLLQTMEP"
     gene            4058..5335
                     /locus_tag="ACF4ZO_000725"
     CDS             4058..5335
                     /locus_tag="ACF4ZO_000725"
                     /EC_number="6.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004326 - tetrahydrofolylpolyglutamate
                     synthase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008841 - dihydrofolate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="folylpolyglutamate synthase/dihydrofolate
                     synthase family protein"
                     /protein_id="HFD5486288.1"
                     /translation="MTYEETLEWIHDHLVFGIKPGLKRMLWVLGQLGNPQKNVKGVHI
                     VGTNGKGSTVNHLQHIFTTAGYEVGTFTSPYIMDFKERISINGRMISEKDLVIAANRI
                     RPLTERLVRETDFGEVTEFEVITLIMFLYFGDMHPVDIAIIEAGLGGLYDSTNVFQAM
                     VVVCPSIGLDHQAILGETYADIAAQKAGVLEGGETLVFAVENPSAREVFLTKAEQVGA
                     SIWEWQEQFQMAENASGYRFTSPLGVISDIHIAMPGHHQVSNAALAIMTCLTLKDRYL
                     RLTSDHIREGLANSLWLGRTELLAPNLMIDGAHNNESVAALVAVLKNNHNDKKLHILF
                     GAIDTKPIADMLVALEQIGDLQVTSFHYPNAYPLEKYPERFGRVADFKDFLALRKHAK
                     ADDFFVITGSLYFISEIRRYWKKHIEKSVLLTH"
     gene            5388..5954
                     /gene="folE"
                     /locus_tag="ACF4ZO_000726"
     CDS             5388..5954
                     /gene="folE"
                     /locus_tag="ACF4ZO_000726"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003934 - GTP cyclohydrolase I activity
                     [Evidence IEA];
                     GO_process: GO:0046654 - tetrahydrofolate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HFD5486289.1"
                     /translation="MSINKEKAEAAIYQFLEAIGENPNREGLLDTPKRVAKMYAEMFL
                     GLGKDPKEEFTAVFKEQHEDVVIVKDISFYSICEHHLVPFYGKAHIAYLPSDGRVTGL
                     SKLARAVEVASKRPQLQERLTSQIADALVEALNPKGTLVMVEAEHMCMTMRGIKKPGS
                     KTITTTARGLYKESRAERQEVISLMTKD"
     gene            5963..6763
                     /gene="folP"
                     /locus_tag="ACF4ZO_000727"
     CDS             5963..6763
                     /gene="folP"
                     /locus_tag="ACF4ZO_000727"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004156 - dihydropteroate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HFD5486290.1"
                     /translation="MKIGKFVIEGNAAIMGILNVTPDSFSDGGSYTTVQKALDHVEQM
                     IADGAKIIDVGGESTRPGCQFVSATDEIDRVVPVIKAIKENYDILISIDTYKTETARA
                     ALEAGADILNDVWAGLYDGQMFALAAEYDAPIILMHNQDEEVYQEVTQDVCDFLGNRA
                     QAALDAGVPKNNIWIDPGFGFAKSVQQNMELLKGLDRVCQLGYPVLFGISRKRVVDAL
                     LGGNTKAKERDGATAALSAYALGKGCQIVRVHDVKANQDIVAVLSQLM"
     gene            6770..7129
                     /gene="folB"
                     /locus_tag="ACF4ZO_000728"
     CDS             6770..7129
                     /gene="folB"
                     /locus_tag="ACF4ZO_000728"
                     /EC_number="4.1.2.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004150 - dihydroneopterin aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0006760 - folic acid-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin aldolase"
                     /protein_id="HFD5486291.1"
                     /translation="MDKIVLESCRFYGYHGAFKEEQTLGQIFLVDLELSVDLQAASLS
                     DQLTDTVHYGMVFDSVRQLVEGGKFILIERLAGAICEQLFNEFPPIEAIKVAIKKENP
                     PIAGHYKAVGIELERQR"
     gene            7126..7626
                     /gene="folK"
                     /locus_tag="ACF4ZO_000729"
     CDS             7126..7626
                     /gene="folK"
                     /locus_tag="ACF4ZO_000729"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003848 -
                     2-amino-4-hydroxy-6-hydroxymethyldihydropteridine
                     diphosphokinase activity [Evidence IEA];
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HFD5486292.1"
                     /translation="MTIVYLSLGTNMGDRAAYLQKALEALADLPQTRLLAQSSIYETT
                     AWGKTGQADFLNMACQLDTQLTAADFLKETQAIEQSLGRVRHEKWGSRTIDIDILLFG
                     EEVYDTKELKVPHPYMTERAFVLIPLLELQSDLKLPPNHKFLRDYLAALDQSDITLFS
                     AQQTEF"
     gene            7776..8663
                     /gene="murB"
                     /locus_tag="ACF4ZO_000730"
     CDS             7776..8663
                     /gene="murB"
                     /locus_tag="ACF4ZO_000730"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008762 - UDP-N-acetylmuramate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HFD5486293.1"
                     /translation="MITELHGIDIRENEPLKHYTYTKVGGPADFLAFPRNHYELSRIV
                     AYANKENMPWLVLGNASNLIVRDGGIRGFVIMFDKLNAVHLNGYTLEAEAGANLIETT
                     KIAKFHSLTGFEFACGIPGSIGGAVFMNAGAYGGEISHIFLSAKVLTSSGEIKTISAR
                     DMAFGYRHSAIQETGDIVISAKFALKPGNYDTISQEMNRLNHLRQLKQPLEFPSCGSV
                     FKRPPGHFAGQLIMEANLKGHRIGGVEVSEKHAGFMINVADGTAKDYEDLIAYVIETV
                     ENHSGVRLEPEVRIIGENL"
     gene            8709..9863
                     /locus_tag="ACF4ZO_000731"
     CDS             8709..9863
                     /locus_tag="ACF4ZO_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD5486294.1"
                     /translation="MTKPIITFNNVSKTFEDSGTQVLKNINFDLEEGKFYTLLGASGS
                     GKSTILNIMAGLLDASSGDIYLDGERINDLPINKRDIHTVFQNYALFPHMTVFENVAF
                     ALKLKKVDKKEIAKRVKETLKMVQLEGYENRSIQKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTEMQYELRELQQRLGITFVFVTHDQEEALAMSDWVFVMNEGEIVQ
                     SGTPVDIYDEPINHFVANFIGESNIINGTMIEDYLVSFNGKEFESVDGGMRPNEPVEV
                     VIRPEDLQITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIEGEVIG
                     LDFTPEDLHIMRLNETEEEFDARIEEYVEMDESEDGLINAIEEERNEENL"
     gene            9847..10641
                     /locus_tag="ACF4ZO_000732"
     CDS             9847..10641
                     /locus_tag="ACF4ZO_000732"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD5486295.1"
                     /translation="MKKTSSLFSIPYFLWILFFVVAPVTLLFYKSFFDIEGRVTLANY
                     ETFFSSWTYLRMSVNSILYAGIITLVTLLISYPTALFLTRLKHKQLWLMLIILPTWVN
                     LLLKAYAFMGIFGQQGGINSFLTFMGIGPQQILFTDFSFIFVASYIELPFMMLPIFNA
                     LDDIDHNVINASRDLGASEFQAFSKVIFPLSLNGVRAGVQSVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLTTQNWGMGSTIGVVLILTMVAIMWLTKEKSK"
     gene            10638..11414
                     /locus_tag="ACF4ZO_000733"
     CDS             10638..11414
                     /locus_tag="ACF4ZO_000733"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD5486296.1"
                     /translation="MKKFANLYLASVFVLLYIPIFYLIFYSFNKGGDMNGFTGFTLEH
                     YQTMFEDSRLMTILLQTFVLAFSSALLATIIGTFGAIFIHHVRGKYQNAMLSANNVLM
                     VSPDVMIGASFLILFTSLKFQLGMSSVLLSHIAFSIPIVVLMVLPRLKEMNQDMVNAA
                     YDLGANYFQMLKEVMLPYLTPGIIAGYFMAFTYSLDDFAVTFFLTGNGFTTLSVEIYS
                     RARQGISLDINALSTIVFFFSILLVIGYYYMSQDKEEKHA"
     gene            11407..12480
                     /locus_tag="ACF4ZO_000734"
     CDS             11407..12480
                     /locus_tag="ACF4ZO_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFD5486297.1"
                     /translation="MRKLYSFLAGVLGVIVILTSLSFILQKKSGSGSQSDKLVIYNWG
                     DYIDPALLKKFTKETGIEVQYETFDSNEAMYTKIKQGGTTYDIAVPSDYTIDKMIKEN
                     LLNKLDKSKLVGMDNIGKEFLGKSFDPQNDYSLPYFWGTVGIVYNDQLVDKAPMHWED
                     LWRPEYKNSIMLIDGAREMLGVGLTTFGYSVNSKNLEQLQAAERKLQQLTPNVKAIVA
                     DEMKGYMIQGDAAIGITFSGEASEMLDSNEHLHYIVPSEGSNLWFDNLVLPKTMKHEK
                     EAYAFLNFINRPENAAQNAAYIGYATPNKKAKALLPDEIKNDPAFYPTDDIIKKLEVY
                     DNLGSRWLGIYNDLYLQFKMYRK"
     gene            complement(12535..13200)
                     /locus_tag="ACF4ZO_000735"
     CDS             complement(12535..13200)
                     /locus_tag="ACF4ZO_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFD5486298.1"
                     /translation="MNVLIIEDDPMVDFIHRNYLEKLNLFDRIISSDSMKAVQSILTD
                     YAIDLILLDIHITDGNGIQFLEKLRAQHIPCEVIIISAANDGNIIRDGFHLGIIDYLI
                     KPFTFERFQESIQQFVTHREHLANQQLEQAQTDQLKCLTSIKDTKNKQLLEKGLSEST
                     FQWIIENIKAFDQPFTIQELASACHLSHVSVRKYIAYLEENKQLNSQQIFTKVGRPYR
                     VYW"
     gene            complement(13181..14722)
                     /locus_tag="ACF4ZO_000736"
     CDS             complement(13181..14722)
                     /locus_tag="ACF4ZO_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spo0B domain-containing protein"
                     /protein_id="HFD5486299.1"
                     /translation="MKKPLRLWASLSLILVSMIVVTTSLFYGIMLHDTHQSIKNQETH
                     LLTSTGKMLASHQAIKELLLNNQPNAKTTAYTNSIASIYNLDYVVVMNMKGIRLTHPN
                     PKNIGKPFQGGDEEAVLAGKKVISTAKGTLGKSLRYLVPVFDGDKQIGAIAVGIKLTT
                     LNDVALTSKRNYTLSLLLCLLISLLVTSFISFRLKRQLHQLEPSEIYQLFEERNAMLD
                     QIEAAVFVVDKAGILQLCNQAGQKLIARKCQLGKPTGNSFNHLFPDFPKLSLQEGHEQ
                     LFRYGEEDYLLAISPICVKNDHRGHIIFMREAVKAIDTLDQLAYTTAYASALQAQTHK
                     FMNQLHVIYGLVDIAYYDQLKIYLDSILEPENEILTSLSVLVKEPLLASFLIGEQEKY
                     QELNVHLKIDVLSEIPHSATKNQLNNGLMIYRFIHTNLLTTLRPKSLVLSIQHDQNHL
                     ISHYTLTDNWIDLERVQPIFDLPYFQQLLTDTNSQFHQHQTVTELQFSVTTPYVGGQH
                     ERFNH"
     gene            14883..16214
                     /locus_tag="ACF4ZO_000737"
     CDS             14883..16214
                     /locus_tag="ACF4ZO_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HFD5486300.1"
                     /translation="METISKKMPQKDLSEHSKAWQNRRIGSVPLPVYLVLATLILVTG
                     WLQQLPVNMLGGFAVILTLGWLLGTIGATIPGLKHFGGPAILSLLVPSILVFFNLLNP
                     NVLEATNVLMKQANFLYFYIACLVCGSILGMNRKILIQGLFRMIIPMLLGMVCAMGVG
                     TLVGVILGLDWQHTLFYVVTPVLAGGIGEGILPLSLGYSAITGVGSEQLVAQLIPATI
                     IGNFFAILCTALLNRFGEKHPSYSGQGQLVKIGHSEDMSDALKDNSGALDVKLMGAGV
                     LTACSLFIAGGLLQHLTGFPGPVLMIILAAFLKYLNVIPQETQNGAKQLYKFISSNFT
                     FPLMAGLGLLYIPLKEVVATLSLQYFIVVISVVLTVVSVGFFVSRFLNMNPVEAAIIS
                     ACQSGMGGTGDVAILSTADRMNLMPFAQVATRLGGAITVITMTAILRIIFS"
     gene            16245..17411
                     /locus_tag="ACF4ZO_000738"
     CDS             16245..17411
                     /locus_tag="ACF4ZO_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent malic enzyme"
                     /protein_id="HFD5486301.1"
                     /translation="MKNQLGQLALEQAKTFGGKLEVQPKVDIKNKHDLSIAYTPGVAS
                     VSSAIAKDKTLAYDLTTKKNTVAVISDGTAVLGLGDIGPEAAMPVMEGKAALFKAFAG
                     VDAIPIVLDTKDTEEIISIVKALALTFGGINLEDISAPRCFEIEQRLIKECHIPVFHD
                     DQHGTAIVVLAAIFNSLKLLQKSLDEVSIVVNGGGSAGLSITRKLLAAGATKVTVVDK
                     FGIINEQEAAQLAPHHLDIAKVTNREFKSGTLEDALEGADIFIGVSAPGVLKAEWISK
                     MAARPVIFAMANPIPEIYPDEALEAGAYIVGTGRSDFPNQINNVLAFPGIFRGALDAR
                     AKTITVEMQIAAAKGIASLVPDDALSTTNIIPDAFKEGVAEIVAKSVRSVVLKS"
     gene            complement(17492..18528)
                     /locus_tag="ACF4ZO_000739"
                     /pseudo
     CDS             complement(17492..18528)
                     /locus_tag="ACF4ZO_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989842.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
     gene            18759..19490
                     /gene="aphA"
                     /locus_tag="ACF4ZO_000740"
     CDS             18759..19490
                     /gene="aphA"
                     /locus_tag="ACF4ZO_000740"
                     /EC_number="3.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030288 - outer membrane-bounded
                     periplasmic space [Evidence IEA];
                     GO_function: GO:0003993 - acid phosphatase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acid phosphatase AphA"
                     /protein_id="HFD5486302.1"
                     /translation="MKKEFTSILFTVSFCGIIALPVEASGPKVPYTQEGITAISNQAT
                     VKLISIADIASSLEGQKPITVSFDIDDTLLFTSQYFQYGKEYITPGSFDFLHKQKFWD
                     LVAKRGDQDSIPKEYAKQLIAMHQKRGDKIVFITGRTRGSMYKKGEIDKTAKSLAKDF
                     KLDKPIAINYTGDKAVKPYQYDKTYYIKKNGSQIHYGDSDEDINAAKEAGARPIRILR
                     APNSTNLPLPKAGGYGEEVLENSAY"
     gene            19668..21200
                     /locus_tag="ACF4ZO_000741"
     CDS             19668..21200
                     /locus_tag="ACF4ZO_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HFD5486303.1"
                     /translation="MENHKNEFTFSNKSIIAYVWRGVMVGIIAGVIVSLFRLLIEVTA
                     DWVIEWYRYAHINSLLLLPILSVSLLAVLFVGFLVKSDSDIKGSGIPHVEGELKGLMS
                     PDWWSVLWKKFLGGIMAISMGFMLGREGPSIQLGAMSAKGLAKFLKSSRLEKRVLIAS
                     GAAAGLSAAFNAPIAGLLFVVEEIYHHFSRLIWITALVASLVANFISLNIFGLKPVLA
                     MSEAMPFLGLNQYWLLLLLGLFLGCLGYLYEIVILNFNKLYVILGSWLHLPAYFYGII
                     MVFLILPIGYYLPQLLGGGHGLILSLSNQQLPLMTIFFYFIIRFIVSMFSYGSGLPGG
                     IFLPILTLGALAGLLFGQIASQLGLLNQSFLSLFLILGMAGYFAAISKAPLTGMILVT
                     EMVGDLKPLMAIAVVTFVSYLVMDLLNGQPIYEAMLDKMAMKHPTNLVEPTLIELTVG
                     DKIAGKYVKELKLPENVLITTQIHHQKSQVVSGNTRLLSGATIFLVVNEADTGFVREV
                     LM"
     gene            21363..21977
                     /locus_tag="ACF4ZO_000742"
     CDS             21363..21977
                     /locus_tag="ACF4ZO_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HFD5486304.1"
                     /translation="MLEIVSEELRHYQEQKLIEYRNKNQLAPKGGIVFAGDSLIEFFP
                     LKKAFGSCLPIINRGIAGIDSQWLLRHFSVQITDLEPKHIFLLIGCNDIGLGYDKCHI
                     VKTIVELISQIRSHCVYSQIYLLSLLPVSNNPRYQKTVKIRTNAMIDAINKDLAMIPT
                     IEFINLNTCLKDEKGGLSDENTLDGLHLNFPAYAKLAEIIQSYI"
     gene            22157..23284
                     /locus_tag="ACF4ZO_000743"
     CDS             22157..23284
                     /locus_tag="ACF4ZO_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFD5486305.1"
                     /translation="MKFEKKQVFYLVLTFILCYGILANWRNGTAIVTTIYKTSLPFFY
                     GAAGAYIVNIVMSAYEKVYVYIFKDWSHVLKVKRGICLLLAYLTFFILITWIISIVIP
                     DLITSISTLTKFDTITIQEVVNNLEHNKLLARTIQYIGGDGKLTETIANYSQQLLKQF
                     LTVLTNILTSVTVIASAIINLFISFVFSLYVLASKEDLCRQGNTLVDTYTGKYAKRIH
                     YLLELLHQRFHGFFVSQTLEAMILGSLTASGMFILRLPFAGTIGVLVAFTALIPVIGA
                     SIGAAIGFILIMTQSMSQAIIFIIFLIILQQIEGNFIYPKVVGGSIGLPAMWVLMAIT
                     IGASLKGIVGMITAVPLAATLYQVIKDNIQKRQAIQKKQVS"
     gene            23333..24013
                     /gene="radC"
                     /locus_tag="ACF4ZO_000744"
     CDS             23333..24013
                     /gene="radC"
                     /locus_tag="ACF4ZO_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HFD5486306.1"
                     /translation="MYSIKCDDNKAMPRERLMRLGAESLSNQELLAILLRTGNKEKHV
                     LELSSYLLSHLDSLADFKKMSLQELQHLAGIGKVKAIEIKAMIELVSRILAIDKTLTD
                     SVLTSVQVAEKMMAALGDKKQEHLVVLYLDNQNRIIEEKTIFIGTVRRSLAEPREILY
                     YACKNMATSLIVIHNHPSGNIEPSSNDYCFTEKIKRSCEDLGIICLDHIIVSYKDYYS
                     FREKSTLF"
     gene            complement(24015..24710)
                     /locus_tag="ACF4ZO_000745"
     CDS             complement(24015..24710)
                     /locus_tag="ACF4ZO_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HFD5486307.1"
                     /translation="MTKPIIGITANQRLNMALDNLPWSYAPTGFVQAVTQSGGLPLLL
                     PIGDEAAAKTYVSMVDKIILIGGQNVGPKYYQEEKAAFDDDFSPERDTFELAIIKEAI
                     TLKKPILGICRGTQLMNVALGGNLNQHIDSHWQEAPSDFLSHEMIIEPDSILYPIYGH
                     KTLINSFHRQSLKTVAKDLKVIARDPRDGTIEAVISTNDAIPFLGVQWHPELLQGVRD
                     EDLQLFRLFVNDF"
     gene            complement(24720..25364)
                     /locus_tag="ACF4ZO_000746"
     CDS             complement(24720..25364)
                     /locus_tag="ACF4ZO_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HFD5486308.1"
                     /translation="MVIDKSIPKATAKRLSLYYRIFKRFHADQVEKASSKQIADAMGI
                     DSATVRRDFSYFGELGRRGFGYDVTKLMNFFADLLNDHSTTNVILVGCGNIGRALLHY
                     RFHDRNKMQIAMGFDTDDNALVGTKTADNIPVHGISSVKERIANTDIETAILTVPSIH
                     AQEVTDQLIEAGIKGILSFAPVHLQVPKGVIVQSVDLTSELQTLLYFMNQNHLD"
     gene            complement(25618..25965)
                     /locus_tag="ACF4ZO_000747"
     CDS             complement(25618..25965)
                     /locus_tag="ACF4ZO_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HFD5486309.1"
                     /translation="MAFEKEIKLKDCKYLYTISPNIKKYTLRDTTFSQTKVGHYQLIR
                     LLEKIPNSGDGFPLKITINKELTGFKLAITDQSGLRLVNIFKTKDNQILQDKFYFLMD
                     SLVEREIFSKTVV"
     gene            complement(25955..27082)
                     /locus_tag="ACF4ZO_000748"
     CDS             complement(25955..27082)
                     /locus_tag="ACF4ZO_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase family protein"
                     /protein_id="HFD5486310.1"
                     /translation="MTYFDNAATTPLSPNVIRAMTAAMQDNFGNPSSIHFYGRRANKI
                     LRECRQAIARNLGASEQQIIVTSGGTESNNMAIKGYALAHQAKGKHLITTTIEHHSVL
                     HTMAYLEERFGFEVTYLPCQNGQINLSDLKQALRDDTILVSIMYANNETGDLLPIKDI
                     GNLLKDHQAAFHVDAVQAVGKLKIIPSELGIDFLSASAHKFHGPKGCGFLYSNGQPID
                     PLLHGGDQEGKRRASTENMLGIIGMAQALTDAMTCLDQSTDHIICLRHHLISLLEGLP
                     YYINQGTHYLPHVLNIGFLGYQNTILLTQLDLAGIAVSTGSACTAGAVNPSHVLAAYY
                     GDDSSRLKESIRISFSDQNSIEDVNQLAQTLKNILGGTDGF"
     gene            complement(27079..28059)
                     /locus_tag="ACF4ZO_000749"
     CDS             complement(27079..28059)
                     /locus_tag="ACF4ZO_000749"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HFD5486311.1"
                     /translation="MTERYADKQIKLFSLTSNLPIAEKIAKAAGIPLGKMSSRQFSDG
                     EIMINIEETVRGDDIYIIQSTSFPVNDNLWELLIMIDACKRASANTVNIVLPYFGYSR
                     QDRVAKPREPITAKLVANMLTKAGIDRVVTLDLHAVQVQGFFDIPVDNLFTVPLFAER
                     YSKLGLSGSDVVVVSPKNSGIKRARSLAEYLDSPIAIIDYAQDDSEREQGYIIGDVSG
                     KKAILIDDILNTGKTFAEAAKILERSGATDTYAVASHGLFAGGAAEVLETAPIKEIIV
                     TDSVKTKNRVPENVTYLSASDLIAEAIIRIHERRPLSPLFSYQPKGKNNA"
     gene            complement(28199..28777)
                     /locus_tag="ACF4ZO_000750"
     CDS             complement(28199..28777)
                     /locus_tag="ACF4ZO_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HFD5486312.1"
                     /translation="MTNLEIEYKTLLTKNEYNRLLSQMKHVTPVTQTNYYIDTKAFDL
                     KANKMSLRIRTFANSAELTLKVPEKVGNREYNVPLFLEQAKDMIKHGNLPESTALDII
                     ISKGIKPSALVTFGNLTTVRRETVIPIGKLALDYNLYANTKDYELELEVSDALQGKID
                     FDSFLSEHHIAFKYAKSKVARCINTLKKFNDK"
     gene            28865..29536
                     /locus_tag="ACF4ZO_000751"
     CDS             28865..29536
                     /locus_tag="ACF4ZO_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015969 - guanosine tetraphosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HFD5486313.1"
                     /translation="MTLDWEEFLDPYIQTVGELKIKLRGIRKQYRKQNRYSPIEFVTG
                     RVKSIESIKEKMILRGVIEENIAQDIQDIAGLRIMVQFVDDVEEVLALLRQRQDMTIV
                     YERDYIRNMKSSGYRSYHVVVEYPVDTIEGQKKVLAEIQIRTLAMNFWATIEHSLNYK
                     YGGDFPEEIKKRLEVTAKIALELDEEMRKIREDIREAQLLFDPVTRNLSDGVGNSDDT
                     DELYR"
     gene            29511..30347
                     /locus_tag="ACF4ZO_000752"
     CDS             29511..30347
                     /locus_tag="ACF4ZO_000752"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003951 - NAD+ kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006741 - NADP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HFD5486314.1"
                     /translation="MTQMNYTGKVKRVAIIANGKYQSKRVASKLFSVFKDDPDFYLSK
                     KNPDIVISIGGDGMLLSAFHMYEKELDKVRFVGIHTGHLGFYTDYRDFEVDKLIDNLR
                     KDKGEQISYPILKVAITLDDGRVVKARALNEATVKRIEKTMVADVIINHVKFESFRGD
                     GISVSTPTGSTAYNKSLGGAVLHPTIEALQLTEISSLNNRVFRTLGSSIIIPKKDKIE
                     LVPKRLGIYTISIDNKTYQLKNVTKVEYFIDDEKIHFVSSPSHTSFWERVKDAFIGEI
                     DS"
     gene            30344..31249
                     /locus_tag="ACF4ZO_000753"
     CDS             30344..31249
                     /locus_tag="ACF4ZO_000753"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HFD5486315.1"
                     /translation="MRFEFVADKRIKVKTLLKSHDVSKGLLAKIKYKGGNILVNGIEQ
                     NAIYLLQVGDVVTIDIPNEEPFEKLEAIPFDLDIVHEDDHFLVINKPIGFASIPSAIH
                     SNTIANFIKAYYVDNHYLDQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQTRSIE
                     KRYFALVSGNGTLPDEGDIIAPIGRSKDSIITRAVDPMGKYAKTSYKVVARYSENVHL
                     VDIKLHTGRTHQIRVHFAHIGFPLLGDDLYGGRLDLGITRQALHCHYLNFKDPFTESD
                     CSYAIHLTDDFDSVIIGLQKKDRGY"
     gene            31253..32248
                     /gene="pta"
                     /locus_tag="ACF4ZO_000754"
     CDS             31253..32248
                     /gene="pta"
                     /locus_tag="ACF4ZO_000754"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008959 - phosphate acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HFD5486316.1"
                     /translation="MSIRSLFGGLREKILGKNMKIVFPEGNDERVVRAAARLKFEGLL
                     EPIILGQSEEVRNLLTKLGFADQDYTIINPNEYADFDKMKETFVDVRKGKATLEDADK
                     MLRDVNYFGVMLVKMGLADGMVSGAIHSTADTVRPALQIIKTKPGISRTSGVFLMNRE
                     NTSERYVFADCAINIDPTAQELAEIAVNTAETAKIFDIDPKIAMLSFSTKGSGKAPQV
                     DKVREATEIAKGLNPDLALDGELQFDAAFVPETAAIKAPDSAVAGQANTFIFPDLQSG
                     NIGYKIAQRLGMFDAIGPILQGLNKPVNDLSRGSSAEDIYKLAIITAAQAIESQG"
     gene            32375..33130
                     /locus_tag="ACF4ZO_000755"
     CDS             32375..33130
                     /locus_tag="ACF4ZO_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HFD5486317.1"
                     /translation="MGNIALVTGASAGFGRAIVEHLIADGIKVIGASRRLEKLKVLET
                     SFGSDNFYPLQMDVTDTKAIDDALTSLPNQWQDITILVNNAGLALGLDKAYEADFENW
                     MTMINTNIVGLIYLTRQLLPHMVSKDDGIIINLGSTAGTIPYPGANIYGASKAFVKQF
                     SLNLRADLVGSHIRVTNIEPGLCEGTEFSKVRFNGDEERVKAIYQGAHAIQPQDIAST
                     VSWVIHQPPHVNVNRIELMPVSQSYGPQPVSRD"
     gene            complement(33324..34013)
                     /locus_tag="ACF4ZO_000756"
     CDS             complement(33324..34013)
                     /locus_tag="ACF4ZO_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug transporter"
                     /protein_id="HFD5486318.1"
                     /translation="MKNASSILALLTPENQLEETFIRELSHHFSHLFEVTILTSKANI
                     QSNQLSTFQGIFSFHEHDIDLPTLYFKTSQHGQGFLVTESVFDQATAVLSLSQYLTGF
                     YQKFDGHFLQYLPLQARLSDANGNIIVDNHAFNGSFLPTTDKEIEDWILAELRLSDNP
                     CKTFLLPSGSLDHIYMQHYQALKNPQGQLVGVLDTVQDIKPLLNRYLEETGQAIVGWS
                     DITSGPSILDH"
     gene            34433..35161
                     /locus_tag="ACF4ZO_000757"
     CDS             34433..35161
                     /locus_tag="ACF4ZO_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD5486319.1"
                     /translation="MIRFNNVSKTFGQTKVLQEQTFQINDREFFVLVGPSGSGKTTLL
                     KMINCLIEPSSGDILLNNVPQKELDLREMRLSIGYVLQQIALFPNLTVAENIAIIPDM
                     KQWSAEEIRQKTEELLDKVGLPAKDYLDRYPSDLSGGEQQRIGIVRAIISHPKILLMD
                     EPFSALDPISRKQLQELMLSLHKEFDMTIVFVTHDIDEAIKLGDRVAILNEGEIVQLD
                     RPEMIKTHPANAFVVNLFGGDEHA"
     gene            35154..36680
                     /locus_tag="ACF4ZO_000758"
     CDS             35154..36680
                     /locus_tag="ACF4ZO_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HFD5486320.1"
                     /translation="MPSLFVTFQNRFNEWLAALGEHLQISLLSLMIALLIGVPLAALL
                     SRSKRWSDIMLQVTGVFQTIPSLALLGLFIPLMGIGTLPAVTALVIYAIFPILQNTIT
                     GLNGIDPSLVEAGIAFGMTKWERLKTFEIPIAMPVIMSGVRTSAVMIIGTATLASLIG
                     AGGLGSFILLGIDRNNANLILIGAISSALLAIIFNSLLQYLEKASLRRIMISFGITLL
                     ALLASYTPMALSQFSKGKDTVVIAGKLGAEPDILINLYKELIEDQSDISVELKSNFGK
                     TSFLYEALKSGDIDIYPEFTGTITSSLLRDKPPLSNDPKQVYEDAKKGIAKQDKLTLL
                     KPFAYQNTYAVAMPEKLAKEYQIETISDLKAHADTLKAGFTLEFKDRADGYKGMQSQY
                     GLQLSVATMEPALRYQAIQSGDIQVTDAYSTDAEITKYHLKVLKDDKQLFPPYQGAPL
                     MKTSLLTKHPELKGILNQLAGKITEKEMQDMNYEVSVKGADANKVARDYLLKTGLIQK
                     "
     gene            36958..37941
                     /gene="guaC"
                     /locus_tag="ACF4ZO_000759"
     CDS             36958..37941
                     /gene="guaC"
                     /locus_tag="ACF4ZO_000759"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007891361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902560 - GMP reductase complex [Evidence
                     IEA];
                     GO_function: GO:0003920 - GMP reductase activity [Evidence
                     IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HFD5486321.1"
                     /translation="MFNDIPVFDYEDIQLIPNKCIITSRSQADTSVTLGKYQFKLPVI
                     PANMQTIIDETIAEQLAKEGYFYIMHRFDEDSRKPFIKRMHEQGLIASISVGVKAYEY
                     EFVTSLKEDTPEFITIDIAHGHANSVIDMIKHIKTELPETFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMVMIGSLFAGHIESPGKTVEVNGETFKEYYGSASAYQKGEHKNVEGKKIL
                     LPTKGHLSDTLTEMQQDLQSSISYAGGKDLDSLRHVDYVIVKNSIWNGDSI"
     regulatory      38064..38159
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            38246..38827
                     /locus_tag="ACF4ZO_000760"
     CDS             38246..38827
                     /locus_tag="ACF4ZO_000760"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016763 - pentosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0043101 - purine-containing compound
                     salvage [Evidence IEA];
                     GO_process: GO:0046110 - xanthine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HFD5486322.1"
                     /translation="MQLLEERILTDGNILGENILKVDNFLTHQVDYRLMKAIGKVFAQ
                     KYAEAGITKVVTIEASGIAPAVYAAEAMDVPMIFAKKHKNITMTEGILTAEVYSFTKQ
                     VTSTVSIAGKFLSKEDKVLIIDDFLANGQAAKGLIEIIGQAGAQVVGVGIVIEKSFQD
                     GRRLIEDMGIEVTSLARIKNFENGNLNFLEADA"
     gene            38827..40110
                     /locus_tag="ACF4ZO_000761"
     CDS             38827..40110
                     /locus_tag="ACF4ZO_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleobase:cation symporter-2 family protein"
                     /protein_id="HFD5486323.1"
                     /translation="MTHSTKQEHSHSQSAVLGLQHVLSMYAGSILVPIMIAGALGYSA
                     RELTYLISTDIFMCGVATFLQLKLTKHTGVGLPVVLGCAFQSVAPLSIIGAQQGSGAM
                     FGALIASGIYVILVAGIFSKIARFFPPIVTGSVITVIGLSLVGVAMGNMGDNVKEPTA
                     QSMMLSLLTIVIILLVQKFTKGFVKSISILIGLVAGTLVSAMMGLVDTTPVVEASWIH
                     VPTPFYFGMPTFEITSIVMMCIIATVSMVESTGVYLALSDLTNDQLDEKRLRNGYRSE
                     GIAVFLGGLFNTFPYTGFSQNVGLVQISGIKTRRPIYYAAGILVVIGLLPKFGAMAQT
                     IPSPVLGGAMLVLFGMVALQGMQMLNRVDFQKNEYNFIIAAVSISAGLGFNGTNLFAS
                     LPETAQMFLTNGIVIATLTSVVLNLVLNGKDKQDE"
     gene            complement(40174..41112)
                     /locus_tag="ACF4ZO_000762"
     CDS             complement(40174..41112)
                     /locus_tag="ACF4ZO_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0017013 - protein flavinylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HFD5486324.1"
                     /translation="MFVTQQLKLMGTVIDIQIESDKACQQLSRVIDLLYTYKNRFSAN
                     DSNSELMAINQAAGVKPVSVHSDLFNLVQIGKAHSLSTPSNLNIAIGPLVQAWRIGFE
                     DARVPSHNLISQQLALTDPRQVLIDDKKQTVFLQQVGMALDLGALAKGYITDKIMAYL
                     IEDGIDSALINLGGNVRVHGPNPKSPDKTFRIGIQKPDAKRGQHLGVIKVNNHSVVTS
                     GIYERQFTSKGKQYHHILDRQTGYPIETDMLSLTIMAPSSFYCDIWTTRLFGLDSSMI
                     ITLLNTFDNIEGLLVTRKHHVLMSNGLRHYFQPYYH"
     gene            complement(41165..41350)
                     /locus_tag="ACF4ZO_000763"
     CDS             complement(41165..41350)
                     /locus_tag="ACF4ZO_000763"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HFD5486325.1"
                     /translation="MPFVTIDLFEGRSQEQKNQLAREVTEVVSRIAKAPKENIHVFIN
                     DMPEGTYYPQGEMKQKS"
     gene            41488..42057
                     /locus_tag="ACF4ZO_000764"
     CDS             41488..42057
                     /locus_tag="ACF4ZO_000764"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000068112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004797 - thymidine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HFD5486326.1"
                     /translation="MAQLYYKYGTMNSGKTIEILKVAHNYEEQGKPVVIMTSALDTRD
                     GFGIVSSRIGMRREAIPISNDIDIFTFIAQLEEKPYCVLIDESQFLSKQNVYDLARVV
                     DELNVPVMAFGLKNDFQNNLFEGSKHLLLLADKIDEIKTICQYCSKKATMVLRTENGK
                     PVYEGDQIQIGGNETYIPVCRKHYFNPEI"
     gene            42092..43171
                     /gene="prfA"
                     /locus_tag="ACF4ZO_000765"
     CDS             42092..43171
                     /gene="prfA"
                     /locus_tag="ACF4ZO_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003747 - translation release factor
                     activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HFD5486327.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSREEANTR
                     ETVTAYREYKQVIQTISDAEEMIKDASGDPELEEMAKEELKESKAAKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAETQGWRFEVMESSVNGVGG
                     IKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRMVHIPTGIKVEMQEERTQQKNRDKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTVGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKMNEVIDALVMYDQTKKLESLNN"
     gene            43171..44010
                     /gene="prmC"
                     /locus_tag="ACF4ZO_000766"
     CDS             43171..44010
                     /gene="prmC"
                     /locus_tag="ACF4ZO_000766"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0018364 - peptidyl-glutamine methylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HFD5486328.1"
                     /translation="MNYATLIRTYEDKLEQIDEDRENLAYVFSEIKEWSSLDMLIHQN
                     QAVTPEDAVLLEHIFCSLSQHLSPQYITGNAYFRDLKLAVDKRVLIPRPETEELVDMI
                     LAENLDAPLNVLDIGTGSGAIAISLKKERPNWQVTASDISRAALDLAKANADAYQLDI
                     TFIESDVFSLISGTFDIIVSNPPYISYEDKEEVSLNVLQSEPHLALFAKENGYAIYRK
                     IIEQADNYLTKEGKLYFEIGYKQAEGIKDMLQAYFPQRHIRVVTDIFGKERMVVVDYG
                     VSS"
     gene            43994..44584
                     /locus_tag="ACF4ZO_000767"
     CDS             43994..44584
                     /locus_tag="ACF4ZO_000767"
                     /EC_number="2.7.7.87"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003725 - double-stranded RNA binding
                     [Evidence IEA];
                     GO_function: GO:0061710 - L-threonylcarbamoyladenylate
                     synthase [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonylcarbamoyladenylate synthase"
                     /protein_id="HFD5486329.1"
                     /translation="MEYLASIIESGDALVLPTETVYGLFAKALDEKAVNAVYDLKQRP
                     RDKAMNLNVADFNSILAFSKEQPRYLKKLYQAFLPGPLTIILKANDQVPYWINSGLST
                     VGFRLPSHPITAALIQKTGPLIGPSANLSGKASGRVFDHIMQDFDFQVFGYADDPFLT
                     GKDSTILDLSGERAVILRQGAITKEELLANVPELRF"
     gene            44602..45054
                     /locus_tag="ACF4ZO_000768"
     CDS             44602..45054
                     /locus_tag="ACF4ZO_000768"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFD5486330.1"
                     /translation="MLRPLSKTDCPMLQEINAKALGYLVSLDLLERQYERLIEDCHHY
                     FLAYADKDTNQLLGYVHAERYETLYASDGLNLLGLAVLPAYQRRGIGSALLRALESQA
                     KQEGIAFIRLNSASHRKEAHAFYQNLDYADDKTQLRFIKNLQGDDNDF"
     gene            45044..46300
                     /gene="glyA"
                     /locus_tag="ACF4ZO_000769"
     CDS             45044..46300
                     /gene="glyA"
                     /locus_tag="ACF4ZO_000769"
                     /EC_number="2.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004372 - glycine hydroxymethyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0070905 - serine binding [Evidence IEA];
                     GO_process: GO:0019264 - glycine biosynthetic process from
                     serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HFD5486331.1"
                     /translation="MIFDKGNVEDFDKELWDAIHAEEERQEHHIELIASENMVSKAVM
                     AAQGSVLTNKYAEGYPGNRYYGGTECVDIVETLAIERAKKLFGAAFANVQAHSGSQAN
                     AAAYMALIEAGDTVLGMDLAAGGHLTHGSPVNFSGKTYHFVGYSVDADTEMLNYEAIL
                     EQAKAVQPKLIVAGASAYSRSIDFEKFRAIADHVGAYLMVDMAHIAGLVAAGVHPSPV
                     PYAHIVTSTTHKTLRGPRGGLILTNDEALAKKINSAVFPGLQGGPLEHVIAAKAVAFK
                     EALDPAFKDYAQAIIDNTAAMAAVFAQDDRFRLISGGTDNHVFLVDVTKVIANGKLAQ
                     ILLDEVNITLNKNAIPFETLSPFKTSGIRIGCAAITSRGMGVKESQTIAHLIIKALVN
                     HNQTVILEEVRQEVRQLTDAFPLYKK"
     gene            46307..47284
                     /locus_tag="ACF4ZO_000770"
     CDS             46307..47284
                     /locus_tag="ACF4ZO_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009295 - nucleoid [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HFD5486332.1"
                     /translation="MLDSYIKRIVIHQFSPNDTELLLSDRLVSITPRIDEYFRKKLAK
                     VFSDEAKRGQFEANNTFFTTIGDDLLETSVTIAQLWKEAFVISEDQKTNDLVFVQFDK
                     DGDPFFAFLRIALKEQFAHLSDNYEHPFTVTQNNLPSPTQTPDEALVINLKSGQYYLI
                     EKRVKHNGSFANYFSEHLLKVTPEQSVKKSIKMIEQTAQKIAEHFNQDDFTFQSKMKS
                     TLFKQLEADDILSPEKLADQLFDDNLTARLTFVDQVKDVIPEPIKISDIDHSRQIKKL
                     ENQKLSLSNGIELTVPNAIYQDAEAVEFLLNDDGTYSILIKNIEDIKTK"
     gene            47285..47884
                     /locus_tag="ACF4ZO_000771"
     CDS             47285..47884
                     /locus_tag="ACF4ZO_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HFD5486333.1"
                     /translation="MFRLLKRACSFLLFFVIYQSFVIHHNVQRVLAYKPMVEKTLAEN
                     DTKANVDLVLAMIYTETKGGEADVMQSSESSSGQKNSITDSQASIEHGVNLLSHNLAL
                     AEEAGVDSWTAVQAYNFGTAYIDYIAKHGGQNTVDLATTYSKTVVAPSLGNTSGQTYF
                     YYHPLALISGGKLYKNGGNIYYSREVHFNLYLIELMSLF"
     gene            47894..49612
                     /locus_tag="ACF4ZO_000772"
     CDS             47894..49612
                     /locus_tag="ACF4ZO_000772"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD5486334.1"
                     /translation="MKRLRPCVKGYLKESILGPLFKLLEALFELLVPLLVANMIDLSI
                     SQHNSQGILRVVLTLFGLATIGLLLSVTAQYFSSKAAVGFTRQMTDDLFKKIMFLSKE
                     DQDHLGYASLLSRLTSDSFQIQTGINQFLRLFLRAPIIVCGAMVMAYWISPSLTLWFV
                     MMVIVLLTLVFVMSHLLGPLYLLIRRETDHLVRLTSQQLQGIRVIKAFNQTQKELQAF
                     KQQNMLLSRHQYQAATLANVLNPMTFLVVNLTLLILIWQGSWQVAHRSLSQGMLVALI
                     NYLLQILAELLKMTMLMGTINQSVTAAKRINQVFVLADEAPLPLLKDGPISTHLLTIR
                     HLTFTYPGAAEPSLYDIQLSADQGEWIGIIGGTGAGKTTLIDLICQTYSQYSGEVSLN
                     WQGEVPKTLTEWRNVIALVPQKAQLFKGTIRNNLLLGQSMPISDEELWRALELAQAKE
                     FVAALPEQLEAPVEAFGRHFSGGQRQRLAIVRALLKPKPILILDDASSALDNETRGRL
                     FKALKEELSDVLVILVTQSIKNLQFADKILVLEQGHQLDFASHDQLKVSNALYQEMLA
                     LYVKGE"
     gene            49615..51342
                     /locus_tag="ACF4ZO_000773"
     CDS             49615..51342
                     /locus_tag="ACF4ZO_000773"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD5486335.1"
                     /translation="MIKTDHHLLKRVLQDLLKKPLPVCILVIASFVQVGLSVYLPVLI
                     GKAVDMSLSVNSWQTLKWLLGQMLVVIVVNTLIQWVMPLVYSRLLYQYSQQLKDKLLE
                     KIHRLPFAYLDRQTIGDLVSRVITDTEQLINGLQMVFNQFILGLLTILCTIIAMAQID
                     WLMLILVLVLTPSSLFLARFIAQKSFHYAQAQTKSRGNLAQFTEEILRQEGLVQLFNA
                     QEQSICDYHVLNKTYCEASQKAIFYASTVNPATRFINSVIYALLAGLGAVRIMAGLFS
                     VGQLTTFLNVVVQYTKPFNDISSVLAEIQSSLACAQRLYDLLDIEIKEQEHFLTFKAS
                     AVKGQIDFEEVSFSYQKDRPLLKDINFSVPAGSKVAIVGPTGAGKSTLINLLMRFYEL
                     DAGSIKLDKVPIKCYAKEELRSITGMVLQETWLKDATVHELIAYGSEEASRDEVVAAA
                     KAAHAHFFIMQLPKTYDTYLSASDDALSQGQLQLLAIARMFLKKPKVLILDEATSSID
                     IRTEAVIQEVLKELMRGRTSFIIAHRLSTIQSADLILVMDQGRLVEWGTHASLMSKNG
                     CYARLQKIE"
     gene            51582..52952
                     /gene="nox"
                     /locus_tag="ACF4ZO_000774"
     CDS             51582..52952
                     /gene="nox"
                     /locus_tag="ACF4ZO_000774"
                     /EC_number="1.6.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="H2O-forming NADH oxidase"
                     /protein_id="HFD5486336.1"
                     /translation="MSKIVVVGANHAGTACIKTMLTNYGDANEIVVFDQNSNISFLGC
                     GMALWIGEQIAGPEGLFYSDKEELESLGAKVYMESPVQSIDYDAKTVTALVDGKNHVE
                     TYDKLIFATGSQPILPPIKGAEIKEGSLEFEATLENLQFVKLYQNSADVIAKLENKDI
                     KRVAVVGAGYIGVELAEAFQRKGKEVVLIDVVDTCLAGYYDRDLTDLMAKNMEEHGIQ
                     LAFGETVKEVAGNGKVEKIITDKNEYDVDMVILAVGFRPNTTLGNGKIDLFRNGAFLV
                     NKRQETSIPGVYAIGDCATIYDNATRDTNYIALASNAVRTGIVAAHNACGTDLEGIGV
                     QGSNGISIYGLHMVSTGLTLEKAKRLGFDAAVTEYTDNQKPEFIEHGNFPVTIKIVYD
                     KDSRRILGAQMAAREDMSMGIHMFSLAIQEGVTIEKLALTDIFFLPHFNKPYNYITMA
                     ALGAKD"
     gene            complement(53111..>53661)
                     /locus_tag="ACF4ZO_000775"
     CDS             complement(53111..>53661)
                     /locus_tag="ACF4ZO_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HFD5486337.1"
                     /translation="GSGTSLDSARFRQALAAKIGVDARSVHAYIMGEHGDSEFAVWSH
                     ANVAGVGLYDWLQANRDIDEQGLVDLFISVRDAAYSIINKKGATFYGIAVALARITKA
                     ILDDENAVLPLSVFQEGQYEGVEDCYIGQPAIVGAYGIVRPVNIPLNDAELQKMQASA
                     NQLKAIIDEAFAKEEFASAAKN"
BASE COUNT        16398 a         9243 c        11102 g        16918 t
ORIGIN      
        1 aaaaaataaa tgtaaaaaaa tcattttttt aataattttt attgacaata gtattataaa
       61 agaatataat tatataggtt ttgataaaaa actgacctaa gacagcaggg gagcatgctc
      121 ataatattcc tgccgaggca caaaacgtga ttaaagaaaa taacgtattt gtactttcgt
      181 gtctaggttt aggtgcgatt ttttttgtac ctagcccaaa aataaaaacg gaggtaaaac
      241 taatgagtga agcaattatt gctaaaaaag ctgaacaagt cgaacttatt gctgagaaaa
      301 tgaaagcagc agcaagtatc gttgttgttg attcacgtgg tcttacagtt gatcaagata
      361 ctgttcttcg tcgttcactt cgtgaaagtg gcgttgagtt caaagttatc aaaaactcaa
      421 ttttgactcg tgcagctgaa aaagcaggtc ttgatgagtt gaaagatgta ttcgtaggac
      481 catctgcagt agcattttct aacgaagatg ttatcgcacc agctaaagtt atcaacgact
      541 ttactaaaac tgctgacgca cttgaaatca aaggtggtgc aatcgaaggc gctgtttctt
      601 caaaagaaga aatccaagca cttgcaacat tgccaaaccg cgaaggaatg ctttctatgc
      661 ttctttctgt acttcaagct ccagtccgca acgttgcata cgctgtcaaa gctgttgcag
      721 aaaacaaaga aggcgctgct taagacgtct cagagtagct taaggctacg cttaacattt
      781 taaattaatt atttggagga aatcacaatg gcattgaaca ttgaaaacat tattgctgaa
      841 attaaagaag cttcaatcct tgagcttaac gatcttgtaa aagctatcga agaagaattt
      901 ggtgtaactg cagctgctcc tgtagctgct gcagctgctg gtggtgctga agaagctgct
      961 aaagattcat tcgacgttga attgacatct gctggtgaca aaaaagttgg cgttatcaaa
     1021 gctgttcgtg aaatcacagg tcttggtctt aaagaagcta aaggtcttgt tgatggagca
     1081 cctgctaacg ttaaagaagg cgttgctgct gcagaagctg aagaaatcaa agctaaactt
     1141 gaagaagctg gagcaacaat cactcttaaa taatagagtc cttgctttag tagcttaaat
     1201 aagctgatta gcccgctatt tttaaaatag cgggtttttt tgaatatcat ttttgatagg
     1261 ttttaataag ccgttattat cgattgttat gataaggcta gttaataatg ttaagcttta
     1321 agtgtaattg agattatttt gataagtggt atttcactta tagtcaattt ttctgagaat
     1381 ttttgctata atagtaacta tgaaagatat aatgataaaa aggtgggcta tccttttttt
     1441 tgtggtatta acttgttcag ggcttagtaa aatagtcctc gcagctgatt ttcaagtggg
     1501 agcagaacat gcgattgtcg tagaggcaga ctctgggaga gttctatatg agaaagacgc
     1561 taagacgcca gatgctattg cctctttgac caaattggtg acggcttatc tggttttaga
     1621 taaggttaaa tcaggccagc tgcaattatc agatcaagtt aatctctcag attatgcctt
     1681 cgagttaaca aaagataggt ctttaagtaa tgtacctttt gacaaaaaaa cttattcagt
     1741 tcaagacctg ttgacagcta ctttggtagc aagctcaaat agcgctgcta ttgcgttggc
     1801 cgaaaaagtg gcgggctcag agcctcattt tgtaaatcaa atgagagaac agctatctca
     1861 ttgggggatt acttctggta aaatcctcaa cgcctcaggt ctgccaaatg aggtgttaaa
     1921 ggaccatcgt tatcctggtt ctgcgttgga agaagaaaat accttgagtg ctcaagatgt
     1981 tgcagttgtg acgatgcgtt tgttagaaga ttttcctgag attttagaga tcaccaaaca
     2041 aacagaagtt aattttgctg gcaattctat taaaagtttt aatcaactct taccaggtat
     2101 ggctaagggt agagcaggag tggatggttt aaagactggg acaacagact tggcaggtca
     2161 ttgtcttgtg gtaacttcta ttgaaaatgg tatgcgagtg attactgtta ttctaaatgc
     2221 cgatggatct gataaaaacc aaaacacgcg gtttgagcaa gcaaatcgtt tgttggacta
     2281 tgtggctaga acttattgtc gtcgtaagat tcttaaaaaa ggaagtcttg tctcggagcg
     2341 gtcgctccct attcaagatg gccaagtaaa agaactaccg gtatctgttg ccgaagatgt
     2401 aaccatcatt ttgcaacagg gtgaacaagt tcccaaacct aaacaattta tgatatcaga
     2461 gacttcttta ctagcaccga ttactaaagg tgaagtggtt gcttatttga cgtctccaag
     2521 aataacagat cagtcagtga ggtatttaaa ggaacctaag cgtattcctc ttaaagctag
     2581 ccaatctctt aaaaaagcct ctgacttaca gctgtggtgg cgagattttc ttgaaaaaag
     2641 acgttaaaga taagaataaa ataattttaa aacaatcaaa aaaagacagt tatgaaagaa
     2701 ttttttcata actgtctttt tagtttacag tgagtatgat ttggaatgat aaaaaaattg
     2761 atgttatggt tccattgttt gtaaaagatt ttcaggactc atgtttggga ggatacgaat
     2821 ccggttaaga gaaagaagtc cattagccgc gctagctatt ccttcgttag tggtaacacc
     2881 taatttatag ttaagtctag ctgcaatttg taaggtagtg tcattatatc taccagatgg
     2941 ataagcaatg gcaatagtgt tttggtttaa ttgcttatca agatagtcct ttgaatcttt
     3001 catttcagtt gtttgaacat caggactagc ctgctctaga tcaggatgat tcactgtatg
     3061 atcttggaaa gacataccga attgtttcat ttctctcatc tgcttaagag tcagattggc
     3121 agcgcttcct atttcggtta gtcctgtaat aacattattg gtggctttag catcatattt
     3181 ttttaagatt gggtaagcaa cgttgtagaa atcaatcata ctgtcatcaa atgttagcca
     3241 tacaactttt ttagcaggca attcattatt tgaaagagcg cggtagacct cttcaggact
     3301 caaaaaatag tagccctcgt ctttcatttt ttgaagttgt tgatcaaaga gatctgggtt
     3361 gacaatcaaa ttagcattag ccgtctcttc aggggacatt acatgaatag catgatacat
     3421 taaaattggg atcttgacag gtgtttcttg cttggtccaa gttaatttag aatgggcctt
     3481 tttttgagat tttgaggaat cgaaatgagt tttcttaagt tttgtcgttt ctttttttgc
     3541 cgtctttttg tgatgaaaaa gacttatttt aggtacaaat tgagagacat ctgacaagcc
     3601 gaatttgtta gacccttgat ataaatagaa aatgagggtc aaaccaagaa tgcaggcaaa
     3661 taatagtata aggttaatga gagtgaaggc ttttcttttt tggcgccgtt tatgtctatt
     3721 gttcattact tgctcctttt tttgatataa gtacctctat tgtaacattt tttagagaaa
     3781 agaaggcttg aagtcagcct tttttcttgt tttttggaag aacgtgtatt aaggagtaaa
     3841 aaaattattg tcacagataa cactttagga ggtagcaaag actatgtggg gctggtattc
     3901 ttatcacgta aaaaaagcaa tgaagataaa agtgtagtgt actttagaac ttatttgagt
     3961 gtttggtgag gataataaaa aaagggtact actctaggtt atctgctgtc actttttttt
     4021 tatatatggt atactaaaga tagatgtgag gtatgaaatg acttatgaag agactctaga
     4081 atggattcat gatcacttag ttttcggcat caagccaggc ttaaaacgta tgctttgggt
     4141 tcttggacag ttaggaaatc cccagaaaaa tgtcaaggga gtgcatatcg ttggaactaa
     4201 cggaaaaggt tccacggtca atcatttaca acatatcttt acgacagctg gttatgaagt
     4261 ggggaccttt acctctcctt acattatgga tttcaaagaa cgtattagca taaatggtcg
     4321 aatgatttca gaaaaagatt tggttattgc tgctaatcgt attcgtcctt tgacagagcg
     4381 tctagttcga gagactgatt ttggagaggt aactgaattt gaagtgatta ctttgatcat
     4441 gttcctctat tttggtgata tgcatcctgt agatattgct attattgaag caggccttgg
     4501 cggtctttat gattcgacca atgtttttca agcaatggtt gtggtctgtc cctcaattgg
     4561 tttagatcac caagctattt tgggagagac ttacgctgat attgccgccc aaaaagctgg
     4621 tgttttagaa gggggcgaga cccttgtttt tgccgttgaa aacccgtcag ctcgagaggt
     4681 ttttttaaca aaagctgagc aggttggtgc ttcaatctgg gaatggcaag agcagtttca
     4741 aatggctgag aacgcatctg gctatcgttt tactagtcct ttaggagtta tttcagatat
     4801 tcacatcgct atgccaggac accaccaagt gtctaatgca gctttagcta ttatgacttg
     4861 cttaaccttg aaagaccgct atcttaggct aacttcagat catataaggg aaggtctagc
     4921 aaatagtttg tggctaggcc gtaccgaatt attagcacca aatctaatga ttgatggggc
     4981 tcataacaat gaaagcgttg ctgctttggt agccgtctta aaaaataacc acaatgataa
     5041 aaagcttcat attttgtttg gtgcgatcga caccaagcct attgcagata tgttggttgc
     5101 tcttgagcaa ataggtgact tgcaggttac tagctttcat taccctaacg cctatccatt
     5161 ggaaaaatac ccagaacgtt ttggtagggt tgctgatttc aaagatttct tggccctgcg
     5221 taagcatgct aaagcagatg actttttcgt gattacaggg tcactatatt ttatttcaga
     5281 aattagacgg tattggaaaa agcatattga aaaaagcgtt cttttaaccc attaaaaaag
     5341 agaaaatgaa aaggaaaagg aaaaaactaa tgaaaaggga aagactaatg tctattaata
     5401 aggaaaaagc agaagcagcc atttatcagt ttttagaggc tattggtgaa aatccaaatc
     5461 gggaaggtct tcttgacacg cctaaacggg ttgctaaaat gtatgcggag atgtttttgg
     5521 gactgggaaa agatcctaaa gaggagttta cggctgtctt taaagaacaa catgaggatg
     5581 tggtgattgt caaagacatt agtttttatt ctatatgtga acaccactta gttccttttt
     5641 atggcaaggc tcatatcgct tacttgccaa gtgatggtcg agtaacaggt ttgagtaaat
     5701 tagcgcgagc agttgaagta gctagtaaac gacctcaact ccaagagcgt ttgacctctc
     5761 aaatagcgga tgctttagtt gaagccctca atcctaaagg gactttagtt atggtagaag
     5821 cagagcacat gtgcatgacc atgcgaggca tcaaaaagcc aggtagtaaa accattacca
     5881 ccactgccag aggcttatat aaggaaagtc gtgctgagag gcaagaagtt atttctctaa
     5941 tgacaaaaga ttaggaggac ttatgaaaat tggaaagttt gtgattgagg gcaatgcggc
     6001 tatcatgggg attttaaatg tgactccaga ttctttttca gatggggggt cttacactac
     6061 tgtgcaaaaa gcattagatc acgttgagca aatgattgct gatggtgcta aaatcatcga
     6121 cgttggtgga gaatcaacac gtccaggttg ccaatttgta agcgctaccg atgaaattga
     6181 ccgggtggtt cctgtgatca aggccatcaa agaaaactat gatattctaa tcagcattga
     6241 tacctataaa accgaaacag ctagagcagc tttagaggcg ggtgccgata ttctcaatga
     6301 tgtttgggca ggtttgtacg acggacaaat gtttgcctta gcagccgagt acgatgcgcc
     6361 tatcatcttg atgcataacc aagacgaaga agtttatcaa gaggtaacac aagacgtttg
     6421 tgattttcta ggcaatagag cacaagcagc tcttgatgct ggcgtgccaa aaaacaatat
     6481 ttggattgat ccaggatttg gatttgccaa atctgttcaa cagaatatgg agttattaaa
     6541 aggattggac cgcgtctgtc agttgggcta tcctgtcttg tttggtattt cgagaaagcg
     6601 tgtcgtagat gccttgttag gcggtaacac caaagctaaa gagcgagacg gagcgacagc
     6661 agccttgtct gcttatgccc ttggaaaagg ctgtcagatt gtacgcgtac acgatgtcaa
     6721 ggctaatcaa gacattgtgg ctgtgttgag ccagttgatg tgaggactta tggataaaat
     6781 cgtattagaa agttgccgtt tttatggcta ccatggagcc tttaaagaag aacagaccct
     6841 tgggcaaatt tttctggttg atttagaatt gtcagtcgat ttgcaagcag cttctttgtc
     6901 agaccaatta acagatacgg tccattacgg gatggtgttt gatagtgtcc gtcagttagt
     6961 ggaaggggga aagtttattt tgattgaacg tttagcaggt gcgatttgtg aacagctttt
     7021 taacgaattt ccacctattg aagccatcaa agtggccatt aaaaaggaaa acccaccgat
     7081 tgcaggccac tataaggcag ttggtattga attggagaga cagagatgac cattgtttat
     7141 ttaagtttag gcaccaatat gggggaccga gcagcttact tgcaaaaagc tcttgaggct
     7201 ttagctgact tacctcaaac acggttgctt gctcaatcat ccatttatga aacgactgct
     7261 tggggcaaga caggccaggc tgattttctc aatatggcct gtcaattaga tacacaatta
     7321 accgcggctg atttcttaaa agaaacacaa gctattgagc aatctcttgg tcgtgtgagg
     7381 catgaaaaat ggggatcaag aactattgac attgatatct tgctatttgg agaagaggtt
     7441 tatgacacaa aggaattgaa agtgccacac ccttatatga ctgagcgtgc ttttgtttta
     7501 atccccttat tggaattgca gtcagattta aaattgcctc ctaatcataa gtttttaagg
     7561 gattatcttg cagctttaga tcaatcagat atcacgctct tttcagctca acagacagag
     7621 ttctagactc tgttttcgga gtaatgcctg ctataagcca atccataaag ttttgccaaa
     7681 ttcatcgtta ttttttctaa aatttgatat aatagtatcg gctttatgcc gattttttta
     7741 cgcgtataag aagtgataaa agaaagaaga taactatgat aactgaactt catgggattg
     7801 atattcgaga gaatgaaccc ctaaaacatt acacttacac taaggtaggt ggcccagcag
     7861 atttcttggc ttttcctaga aatcactacg agctatcacg catcgttgct tatgccaaca
     7921 aagaaaatat gccttggctt gttttgggaa atgccagcaa tctcattgtg cgagatggtg
     7981 gtattcgtgg ctttgtcatc atgtttgata agctaaatgc agtgcactta aatggttata
     8041 ccttagaagc cgaagctggt gccaatctga ttgaaacaac gaagattgcc aaattccata
     8101 gtttaacagg gtttgaattt gcatgtggca ttcctggaag cattgggggt gctgttttta
     8161 tgaatgcagg tgcctatggt ggggaaatat cacatatttt cttatccgct aaggtgctta
     8221 cctcaagtgg agagatcaaa accatttcag ctagggatat ggcttttggt taccgtcact
     8281 ctgccattca agaaacaggt gacattgtca tttctgctaa gtttgctctt aaaccgggta
     8341 attatgatac gatcagccaa gaaatgaatc ggttaaatca ccttcgccaa ctaaaacaac
     8401 ctttagaatt tccatcttgt ggatctgtgt ttaagcgccc gccaggacac tttgcaggtc
     8461 aattaatcat ggaagcaaat cttaaagggc atcggattgg tggtgtggaa gtttccgaaa
     8521 aacacgctgg ttttatgatt aatgtggcag atggcacagc taaagattat gaagatttga
     8581 ttgcttatgt cattgagaca gttgaaaacc attctggtgt caggcttgaa ccagaagttc
     8641 ggattattgg ggaaaacctg taaccattat tgataattaa agaaagtacc gtggaggatt
     8701 tatgacaatt gactaagcca attatcacat ttaacaatgt ttcaaaaaca tttgaggaca
     8761 gtggaacaca ggttctaaag aacattaact ttgaccttga agaaggaaaa ttttacaccc
     8821 tgcttggagc ttctggctct ggaaaatcaa ctattttaaa tattatggcg ggcctactag
     8881 atgccagcag cggagacatt tatttagatg gggaacgtat taatgatttg ccgattaata
     8941 aacgtgacat tcataccgtt ttccaaaatt atgccctctt ccctcatatg actgtttttg
     9001 agaatgttgc ctttgctttg aagctgaaga aagttgacaa gaaagagatt gctaagcgcg
     9061 tgaaagaaac cttgaaaatg gttcaattag aagggtatga aaatcgttct atccagaagt
     9121 tatctggtgg tcaacgtcaa cgtgttgcca ttgcgcgtgc gattatcaat caaccgcgtg
     9181 tggtcttact tgacgaacca ctctcagccc ttgatttgaa attaagaaca gagatgcaat
     9241 atgaattacg tgaattgcaa caacgtctag gcattacctt tgtttttgtt actcacgatc
     9301 aagaagaagc cttggccatg agtgattggg tttttgtcat gaatgaaggt gaaattgttc
     9361 agtcgggaac accagtggat atttacgatg agccaattaa tcattttgtt gctaatttta
     9421 ttggagaatc taatattatt aacggtacca tgattgaaga ctatcttgtc tcctttaacg
     9481 ggaaagaatt tgaatctgtg gacggtggga tgcgccctaa tgagcctgtt gaagtggtta
     9541 ttcgtcctga agatcttcaa atcactttgc cagaagaagg gaaattacaa gttaaggttg
     9601 atacccaatt attccgcggg gttcactacg aaattattgc ctatgatgaa ttgggtaatg
     9661 aatggatgat tcattctacc cgcaaagcta tcgagggaga agttatcgga ttagacttta
     9721 cccctgaaga tcttcatatc atgcgtctta atgagactga agaggaattt gatgcccgta
     9781 ttgaagaata tgtggaaatg gatgagtctg aagatggatt gattaatgcc attgaggagg
     9841 agcgtaatga agaaaacctc tagtcttttt tcgattcctt acttcttatg gattctcttc
     9901 tttgttgtgg caccagtcac tctcttgttt tacaagtcct tttttgacat agaagggcgc
     9961 gtgaccttag ccaattatga aacctttttt agctcttgga cctatttgag aatgagtgtg
    10021 aattctattt tatacgctgg tattatcaca ctcgtcacgc tcttgatttc atatcctacg
    10081 gctctctttt taacgcgcct aaagcacaag cagttgtggc ttatgctcat tattttgcca
    10141 acttgggtaa acttattgct aaaagcctat gcctttatgg gaatctttgg tcaacaagga
    10201 ggaattaaca gctttttaac ctttatgggg attggcccgc agcaaatcct tttcacggat
    10261 ttctccttca tttttgtagc ctcttacatt gagctccctt ttatgatgtt accgattttt
    10321 aacgctttgg atgatattga ccataatgtc attaatgcca gtcgcgacct aggagctagt
    10381 gaatttcagg ccttctcaaa agttattttt cccctttctt taaatggggt tagggcaggt
    10441 gttcagtctg tctttatccc aagtttgagt ctctttatgt taacccgttt gattggtgga
    10501 aaccgcgtga ttacacttgg tacagccatt gaacaacatt ttttgaccac ccaaaactgg
    10561 ggaatgggat caaccatagg tgtggtgtta atcttaacca tggttgctat tatgtggctc
    10621 acaaaggaga aaagtaaatg aaaaaatttg ccaatcttta tttagcgagt gtctttgttt
    10681 tactctacat tcctattttt tatttgattt tctattcttt caacaaaggt ggggatatga
    10741 atggttttac aggatttacc cttgagcatt accaaaccat gtttgaggat agtcgtctca
    10801 tgacaatctt actgcaaacc tttgttcttg cttttagtag cgctctacta gcaacgatta
    10861 ttgggacctt tggagctatc tttatccacc atgttagagg taagtaccaa aatgccatgc
    10921 tatcagccaa taatgtcttg atggtatcac cagatgtcat gattggggct tcctttttaa
    10981 ttctttttac atcattgaag tttcagctgg gcatgtcttc agttttatta agtcatattg
    11041 ctttttcgat tcctattgtg gttttgatgg tattgccgcg cttgaaagag atgaatcaag
    11101 acatggtcaa cgccgcttat gatttgggag ctaattattt ccaaatgctc aaagaagtca
    11161 tgctgccata cttaacacca gggattattg caggttattt tatggccttt acctattcct
    11221 tagatgattt tgcagtgact ttctttttga ctggaaatgg ttttactact ttatctgttg
    11281 agatttattc gcgggctcgt cagggaattt ccttggatat caatgctttg tcaaccatcg
    11341 ttttcttttt ctccatcctc ttagtgatcg gttactatta tatgtcacag gacaaggagg
    11401 aaaaacatgc gtaaacttta ttcctttcta gcaggagttt tgggtgttat tgttatttta
    11461 acaagccttt ctttcatctt gcagaaaaaa tcgggttctg gtagtcaatc ggataaatta
    11521 gttatttata actggggaga ttacattgat ccagctttgc tcaaaaaatt caccaaagaa
    11581 acgggcattg aagtgcagta tgaaactttc gattctaatg aagccatgta cactaaaatc
    11641 aagcagggcg gaaccactta cgacattgct gttcctagtg attacaccat tgataaaatg
    11701 atcaaagaaa acctactcaa taagcttgat aagtcaaaat tagttggcat ggataatatc
    11761 gggaaagaat ttttagggaa aagctttgac ccacaaaacg actattcttt gccttatttc
    11821 tggggaaccg ttgggattgt ttataatgat caattagttg ataaggcgcc tatgcactgg
    11881 gaagatctgt ggcgtccaga atataaaaat agtattatgc tgattgatgg agcgcgtgaa
    11941 atgctagggg ttggtttaac aacttttggt tatagtgtga attctaaaaa tctagagcag
    12001 ttgcaggcag ccgagagaaa actgcagcag ttgacgccga atgttaaagc cattgtagca
    12061 gatgagatga aaggctacat gattcaaggt gacgctgcta ttggaattac cttttctggt
    12121 gaagccagtg agatgttaga tagtaacgaa caccttcact acatcgtgcc ttcagaaggg
    12181 tctaaccttt ggtttgataa tttggtacta ccaaaaacca tgaaacatga aaaagaagct
    12241 tatgcttttt tgaactttat caatcgtcct gaaaatgctg cgcaaaatgc tgcatatata
    12301 ggttatgcga caccaaataa aaaagccaag gccttacttc cagatgagat aaaaaatgat
    12361 cctgcttttt atccaacaga tgacattatc aaaaaattgg aagtttatga taatttaggg
    12421 tcaagatggt tggggattta taatgattta tacctccaat ttaaaatgta tcgcaaataa
    12481 gcactcaaaa aggctggtat ttctccagcc tttttaatgt atcgacagat gacgtcacca
    12541 gtacacgcga tagggacgac caaccttggt aaaaatttgt tggctgttca gttgcttatt
    12601 ttcttctaaa taagcaatgt atttacggac agagacatgg gataagtgac aagcggaagc
    12661 taattcttgg atagtaaaag gttgatcaaa ggctttgata ttttctataa tccactggaa
    12721 agtggattca gataagcctt tttctaacaa ttgtttgttt ttagtgtctt ttatgctagt
    12781 caaacatttc agttggtcag tttgggcctg ctctagttgc tgattggcca aatgttctcg
    12841 atgcgtaaca aactgttgga tgctttcttg aaagcgttca aaggtaaagg gcttgatgag
    12901 gtagtcgata attcctaaat gaaaaccatc tcggataata ttcccatcat ttgcggctga
    12961 aataataatg acttcgcaag gaatatgctg agcacgcaat ttctccaaaa attgaatccc
    13021 attgccatct gtaatatgaa tatccagtaa aatgaggtca attgcgtaat cagtaagtat
    13081 gctttgaaca gctttcatag agtcgctgga tataatgcga tcaaaaagat ttagtttttc
    13141 gaggtaattg cgatggataa aatccaccat gggatcatct tcaatgatta aaacgttcat
    13201 gttgccctcc tacataaggt gttgtcactg agaactgtaa ctcggttacg gtttgatgtt
    13261 gatggaattg ggaatttgta tcggtcaaga gctgttgaaa ataaggtaag tcaaaaatag
    13321 gctgtacccg ctccaaatca atccaattgt ctgtcaaggt gtaatggctg attaaatgat
    13381 tctgatcatg ttgaatactc aaaacgagtg atttgggtct cagtgtggtt agaagattag
    13441 tatggataaa gcggtaaatc atcaaaccat tattaagttg attcttggtg gcagaatgag
    13501 gaatctcgct taaaacatca atcttgagat ggacatttaa ttcttggtat ttctcttgct
    13561 ctccaatgag aaaactagct agaagaggct ccttaacaag gacagataag ctagtgagaa
    13621 tttcattttc gggctccaaa atactgtcta aataaatttt caattggtca taataagcaa
    13681 tatctactaa gccataaata acatgcaatt gattcatgaa tttatgagtt tgggcttgta
    13741 gagcagaagc ataggcggtg gtataggcta gctgatccaa ggtatcaata gccttaactg
    13801 cttctcgcat gaaaataatg tggcctcggt gatcgttttt gacacagatg ggtgaaatgg
    13861 ctaacaagta gtcttcctca ccataccgaa agagttgttc atgcccctct tgcaaactaa
    13921 gttttggaaa atcaggaaag aggtgattga aactgttgcc agtaggtttt cccaactggc
    13981 atttccgagc aattaatttt tgtccagcct gattgcagag ctgtaagata ccagctttat
    14041 ctaccacaaa tacggcggct tcgatttgat ccaacatggc attacgctct tcaaagagct
    14101 ggtaaatttc acttggttct aactggtgca gttgacgctt gagtcgaaaa gaaataaaac
    14161 tggtgaccag taaactaata agaagacaaa ggagtaaaga cagggtataa ttgcgttttg
    14221 acgttaaagc cacatcattt agggtagtta gtttaatgcc aaccgcaata gcaccaatct
    14281 gtttgtcacc gtcaaacaca ggtactagat agcgaagtga ctttcctaaa gtgcccttgg
    14341 cggtagaaat aacctttttt cctgctagaa cagcctcctc atcacctcct tgaaaaggtt
    14401 ttccgatatt tttcgggtta ggatgggtga gtcgaatccc tttcatgttc atcacgacca
    14461 cataatcaag gttatagatg gaggcaatgg agttggtata ggctgttgtt ttagcatttg
    14521 gttggttgtt taggagtaat tctttaatcg cttgatgact tgctaacatt tttccagttg
    14581 acgttagcaa atgggtttcc tgatttttga tggattggtg cgtatcatgt agcataatcc
    14641 cgtaaaatag agaggttgtg acaacaatca tagataccaa aatcaacgat aaactggccc
    14701 ataaacgtag tggttttttc ataaggtctc ctctttattg agtataacac gataagaaat
    14761 gacctgctag cttaaattaa ttaaataact tgaaaaaatt aaagtagtta aacaacttaa
    14821 ataaactatg cttttgacat gttctctttt atactagcct tatcactaaa ggaggttgtt
    14881 tcatggaaac aataagcaag aaaatgcctc aaaaagactt gtctgagcat tcaaaagcat
    14941 ggcaaaatag gcgaataggc tccgttccct tgcctgttta tctggtttta gctaccttaa
    15001 ttttagtcac aggctggctc caacaattgc ctgttaatat gctgggtggc tttgctgtta
    15061 ttttaaccct tggttggcta ctaggaacca ttggagcgac cattccaggc ctcaaacatt
    15121 ttggtggccc agctatttta tcactcttag tcccttcgat tttggttttt tttaatctcc
    15181 tcaatcccaa tgtcttagaa gcgacgaatg tcttgatgaa gcaagccaat tttctttatt
    15241 tttatattgc ctgcctggtc tgcggtagta ttttaggcat gaatcgaaaa atcttgattc
    15301 aaggtctttt tcggatgatt attcccatgt tacttggaat ggtttgtgca atgggtgtag
    15361 ggactttggt tggcgtcatt ttaggattag actggcaaca taccctcttt tatgttgtga
    15421 cgccagtcct tgctggagga attggtgaag gtattttacc cttatccctt ggttacagtg
    15481 ccattacagg agtcggaagt gagcaattag tggctcaact gattccagcc accattattg
    15541 ggaatttctt tgctatcttg tgcacggctt tgctcaatcg ttttggagag aagcacccaa
    15601 gttattctgg tcaagggcaa ctggttaaaa ttggtcacag cgaagacatg tctgatgccc
    15661 taaaagacaa ttctggagcc ttagatgtta aattaatggg ggcaggagtt ttaacagctt
    15721 gttcactttt tattgccggt ggcttgttac agcatttaac aggttttcca ggaccggtgt
    15781 tgatgattat tctggcagcc ttcttgaaat acctgaatgt tattccccaa gaaacccaaa
    15841 atggtgccaa acaactttat aaatttattt ccagcaactt tacttttccg ttaatggcag
    15901 ggcttggtct gctttatatc cccttaaaag aggttgtggc aacccttagc ttgcaatatt
    15961 ttattgtggt gattagtgtg gtgttaacgg ttgtcagtgt cggtttcttt gtctctcgct
    16021 tccttaacat gaaccctgtt gaagcagcta ttatttcagc ttgtcaaagt ggtatgggtg
    16081 gaaccggcga tgtggctatt ttgagtacgg ctgaccgcat gaatctaatg ccgtttgccc
    16141 aagtcgctac ccgtctaggt ggggctatta ccgttatcac tatgacagct attttaagaa
    16201 ttatttttag ttaatccaaa ccaataaaaa gagaggtatt tcctatgaaa aatcaattag
    16261 gtcaacttgc ccttgaacaa gccaaaacgt tcggaggtaa attggaagtt caaccaaaag
    16321 ttgacattaa aaataaacat gatttgagca ttgcctatac accaggtgta gcgagtgtgt
    16381 catctgccat cgcaaaagat aaaacattag catatgactt aaccaccaag aaaaatacag
    16441 tagccgttat cagtgatggt actgcggttc ttggtctggg ggatattggc cctgaagcag
    16501 ccatgccagt tatggaagga aaagcagccc tttttaaagc atttgcaggt gtcgatgcta
    16561 ttccaattgt attagatacc aaagatactg aagaaatcat aagtattgtc aaagcacttg
    16621 ccctaacctt tggtggcatt aacttggaag atattagtgc gccccgctgt tttgaaattg
    16681 agcaacgctt aattaaggaa tgtcatattc ctgttttcca tgacgatcag catggaacag
    16741 ctattgtggt gttagcagcc atcttcaata gtttgaaact tcttcaaaaa tcccttgatg
    16801 aggtatccat tgtggtgaac ggtggtggat ctgctggatt atccattacc cgtaaattat
    16861 tagcagcagg tgctacgaaa gtgacagtag tggataaatt tggcattatc aatgaacaag
    16921 aagccgctca attagcgcca catcatttgg atatagcgaa agtcactaat cgtgagttta
    16981 aatcaggtac cttagaagat gctcttgaag gagcagatat cttcattggc gtatcagcac
    17041 caggagtctt aaaagcagag tggattagta aaatggcagc gcgcccagta atttttgcca
    17101 tggccaaccc tattccagag atttaccctg atgaagccct tgaagcgggg gcttacattg
    17161 taggtactgg ccgcagtgat tttcctaacc agattaataa tgtccttgcc tttccaggta
    17221 tttttagggg agcattagat gcacgggcaa aaaccattac tgttgagatg caaattgctg
    17281 ccgcaaaagg tattgccagt cttgtcccag atgacgcttt gagcactact aatattattc
    17341 cagatgcctt taaagaagga gtcgctgaga ttgtcgctaa aagcgtcagg tcggtagtcc
    17401 ttaaatcata gaatatatga aaaaagagaa agttatactt taaatcacaa aataagtaga
    17461 agcatatttc tagcttctac ttattttgtg attagctaat atcattatca ataataactt
    17521 tcaaggcgtt atttgcacca gcatgtttaa aggtttcata agctttttca acttctgaaa
    17581 gtttaaaatg atgtgtaata aatcttgttg cgtcaatctt tccagttttc aagacattta
    17641 gtagcatttc agttgtattg gcgtgtttaa ggtgatattt ttaatccata attcatccag
    17701 gttgaaatca actggtttcc catgaacccc aacgttagca atatgcccac ctactgatat
    17761 aattttttga caaatatcaa atgtcgcggg ataaccaaca cactccatgg aaatatcgac
    17821 accacgtcca ttggttatat cgtcaatgat agccttgact tcttcactac ttcctgaaca
    17881 aatcgtgtgt gtggctccaa acgttttagc tgcttcaagg cgattttgag ataagtcgac
    17941 cataataata ttggctggag agaaaaattg aacggttagt agggctgcga gtcctactgg
    18001 accggcacca acaatacaaa cattatctcc aggcttgaca tgtgatggca agacaccaat
    18061 ttcatatgaa gttggtaaaa tatcagaaag catgaccagt gcctcatcat caatcgtatc
    18121 aggagcatga tagagactac catctgcatg tgggatatgg acatattctg cttgtgttcc
    18181 attaattaaa tggccaagaa tccaaccgcc atcttcacaa tgtgacgaaa ggcctcgttt
    18241 acaataataa caggtatgac atgatgtgac gcaagaaata atcactttat ctccgatttt
    18301 aaagttagtg accgcatcac cgacctcctt aacaattcca attccttcat gaccaaggat
    18361 tgttccttct ttacatgcgg gaacatcccc acctaagata tgcaaatcag ttccacaaat
    18421 agtggttttt accacctgga cgatagcatc tgtaggcttt ataatgactg gttttggttt
    18481 gtctatgagc tgtagatttc cggttgaaag gtaagttgct gctttcatat ttaactcctt
    18541 ataaggttga gaggtaatca accaattcat ttttacacag atattataat attttaagaa
    18601 agggttttca atatttttta aatcgattat gataattttt tagatcatct ttgttgaata
    18661 acttcatcct tattcagaac tggcactatt ataagaattt gaaaccgctt tacttaaatc
    18721 gtgtattttt gtacaataat gattaaggag gtttttagat gaaaaaagaa tttaccagta
    18781 tcctgtttac agttagtttt tgtggaatca tagcattgcc tgtcgaagct agtggcccta
    18841 aagttcctta tacacaagaa ggtataacgg ccatttcaaa tcaggcaaca gtaaaattga
    18901 tttctattgc tgatatcgcg agcagtttag aaggacaaaa acctataacg gttagttttg
    18961 atatcgatga tactttgtta tttactagcc aatattttca gtacggcaaa gaatatataa
    19021 ctccaggctc atttgatttt ttgcataagc aaaaattttg ggacttagtc gctaaacggg
    19081 gagatcagga ttctattcca aaagagtatg caaagcaact aatcgcaatg catcaaaaac
    19141 gaggagataa aattgtcttt attactggcc gaactcgagg atcgatgtat aaaaaaggtg
    19201 agattgataa aacagctaag tcactggcta aagattttaa gttagacaag ccaatagcta
    19261 tcaattatac aggagataaa gctgtgaagc cgtatcagta tgataaaaca tattatataa
    19321 agaaaaacgg ctcacaaatt cattacggag atagtgatga agatataaat gctgccaaag
    19381 aggcaggtgc aagacctatt cgcattttaa gagctcctaa ttcaaccaat cttcctttgc
    19441 caaaagctgg aggatacgga gaagaggttt tagaaaattc ggcttattag tcaaatattt
    19501 gtgtaagaaa ggaagtaaca gtaatttctt tcatcacccc actgagtaac caatagccca
    19561 gtgggttttt tgggttacag aaatcagttc taaaaaagaa tcactggtaa cttaaggttg
    19621 actttgatac aatggtaaca gtgtatttaa aagaaagaga ggacaacatg gaaaaccata
    19681 aaaatgaatt caccttttcc aacaaatcaa ttattgccta tgtttggcgt ggtgttatgg
    19741 ttggtattat tgctggtgtt attgttagtt tattccggtt gttaattgaa gtgacagctg
    19801 actgggtgat tgaatggtac cgatacgctc atatcaattc gctgttgcta cttcctatac
    19861 taagtgtcag tttgttagct gttctttttg taggtttttt agtaaagtct gattctgata
    19921 taaaaggatc aggaatcccc catgtcgaag gagaactaaa ggggctaatg tccccagatt
    19981 ggtggagtgt cctttggaaa aaatttttag gaggaatcat ggctatttct atgggattta
    20041 tgctcggtcg tgagggtcct tcgattcagt taggtgctat gtcagccaaa ggattagcta
    20101 agtttttaaa atcgagtcgt ttggaaaagc gagtgctaat tgccagcgga gcagcagcag
    20161 ggctatcagc agcttttaat gctccaatag caggcctctt gtttgttgtt gaagaaattt
    20221 accatcattt ttcgcgttta atttggatta cagcgctagt ggctagctta gtggctaatt
    20281 ttatttctct gaatattttt ggattgaaac cagtcttagc aatgtcagag gcgatgcctt
    20341 ttttaggact caatcaatat tggttgttgc ttttacttgg attatttcta ggctgcttag
    20401 gctatttata tgagatagtt atccttaatt ttaataaact ttatgttatt ttagggagtt
    20461 ggttacatct gccagcttat ttttacggta ttattatggt ttttctaatt ttaccgattg
    20521 gctattattt accacagtta cttggaggag gacatggttt aatactttct ttatccaatc
    20581 aacaattgcc tttgatgact atcttctttt attttattat tcgatttatt gttagtatgt
    20641 ttagttatgg aagtggctta cctggaggta tttttttacc tattttaact ttaggtgctt
    20701 tggcaggcct attatttggg caaatagctt ctcaattagg tttattgaac caatcttttc
    20761 tttctctttt tttgatatta gggatggcag ggtattttgc ggcaatttca aaagcaccac
    20821 tgacaggcat gattttggta actgaaatgg taggtgattt gaaaccctta atggccatag
    20881 ctgtagttac ttttgtctcc tatttagtga tggatttgtt aaatggacag ccaatttacg
    20941 aagctatgct agataagatg gcaatgaagc atccaactaa tcttgttgaa ccaacattaa
    21001 ttgaattgac tgttggtgat aagattgcag ggaaatatgt taaagagtta aagcttccag
    21061 aaaatgtctt aattacaacc caaattcacc atcaaaaatc tcaagttgtg tcaggtaaca
    21121 cgcgcctttt atcaggagca actatctttt tggtcgttaa tgaagctgat acaggttttg
    21181 tccgtgaggt attgatgtag gtattaattt atcacaattc ggaaagttcg agcttgtctt
    21241 ttagactaag tcttcgaatg ttttactgct agagtttcat ctgaaccaaa gtgaaacgct
    21301 tttggtgaag tcaagtaggc tttttgttat actaacaata aagataagct aaggaggctg
    21361 agatgttaga aattgtttca gaagagctac gtcactatca agaacaaaaa ttgattgagt
    21421 accgtaacaa aaatcagtta gccccaaaag gaggcattgt atttgcaggt gattctctca
    21481 ttgaattttt tcctttaaaa aaagcttttg gttcatgttt gcctattatt aatcgaggta
    21541 ttgctgggat agatagtcaa tggttattgc gccatttttc tgtccaaatt actgatttag
    21601 agcctaaaca tattttttta ttaattggtt gtaatgatat cgggcttgga tatgataaat
    21661 gtcatattgt caagactatt gtagagctta ttagccagat tcgtagtcat tgtgtctaca
    21721 gtcagattta tctcttatct ttattaccag tttccaacaa tccccgatat cagaaaactg
    21781 tcaaaataag aacaaatgct atgattgatg ctattaataa agatttagca atgattccaa
    21841 ctatagaatt tattaatctt aatacttgtc ttaaagacga aaaaggtggt ttatcagatg
    21901 agaatacact agatggttta catcttaatt ttccagctta tgctaaacta gctgaaatta
    21961 ttcaatctta tatctagcca ataaatgtac taatagcgat gaggcaagaa gtcagatagc
    22021 agatggttca tcaatcaatt aagaaaaaag ttatcaagat accattaaaa atagttgctc
    22081 aaagttcttt caaatcaaaa gattatgata tcgctatgtt gagttttagt gtataatgat
    22141 aattaaagga gttaccatga aatttgaaaa aaaacaagtc ttctatttag tccttacgtt
    22201 tatcttatgc tatgggatcc tagcaaactg gcgaaatgga acggctatcg tcacgactat
    22261 ttacaaaaca agccttcctt ttttttatgg agcagcaggt gcctatattg ttaatattgt
    22321 aatgagcgct tacgaaaagg tatatgttta tatctttaaa gactggtcac atgtcttaaa
    22381 agtaaaacgg ggtatttgtt tactgttagc gtatttgaca ttttttattt taattacttg
    22441 gattatttcc attgtcattc cagacttaat tacaagtatt agtactctaa caaaatttga
    22501 tactataacg atacaagaag ttgttaacaa tcttgagcac aataaactgt tagcacgtac
    22561 tattcagtat attggtggcg atggcaaact tacagagacg attgctaact atagtcaaca
    22621 gttattaaag caatttctta ctgttttgac aaatatttta acatctgtta cggttattgc
    22681 ttctgcaatt attaatcttt ttattagttt tgttttttcg ttatacgttt tagcaagtaa
    22741 agaagatctt tgtcgtcagg gaaatacttt agtagatact tatactggta agtacgctaa
    22801 acgcattcat tacttgttag agttgttgca tcagcgtttt cacggatttt ttgttagtca
    22861 gaccttagaa gctatgattt taggttcgct gactgctagt ggcatgttta tattaagatt
    22921 accatttgca gggactattg gcgttttagt agcttttaca gcattgattc cagttatagg
    22981 tgcttcaatt ggagcagcta ttggatttat tttaattatg actcagtcca tgtcacaggc
    23041 cattattttt atcatttttt taattatttt gcagcagatt gaaggcaatt ttatttatcc
    23101 gaaagtagtt ggtggatcga ttggattacc ggctatgtgg gtattaatgg caattacaat
    23161 aggcgcttct ttaaagggaa tagttggtat gattactgca gttcctttag cagcgacact
    23221 ttatcaagtg attaaagata atattcaaaa aagacaagct attcaaaaaa aacaagtttc
    23281 ctaaaaggaa cttgtttttt tgtcgaataa aaagatggag gtaatatgat aaatgtattc
    23341 tataaaatgt gatgataata aagccatgcc aagagaacgt ttgatgcgac taggagcaga
    23401 gtctctaagt aatcaagaat tattagcaat tttattacga acaggtaata aagaaaagca
    23461 tgtcttagag ctgtcatcct atcttttatc gcatttagac agtctggcag attttaaaaa
    23521 gatgtctttg caagaattac aacatttggc aggtatagga aaagttaaag cgattgaaat
    23581 taaagctatg attgagttgg tttcccgaat tttagcgatc gataagacat taactgatag
    23641 cgtattaacc agtgttcagg tcgctgaaaa aatgatggca gctttaggag ataaaaaaca
    23701 agagcattta gtcgtattgt atttagataa tcaaaatcgt attattgaag aaaaaactat
    23761 ttttattggg actgtccgac gttcacttgc agaaccaaga gaaattttat actatgcctg
    23821 taaaaatatg gcgactagtc tcattgttat tcataatcat ccttcaggaa atattgaacc
    23881 tagttctaac gattattgct ttactgaaaa aataaaacga tcatgtgaag atttaggcat
    23941 tatctgtcta gatcacatta tcgttagcta taaagattat tatagttttc gagaaaaatc
    24001 aacccttttt taaatcagaa gtcattgacg aataagcgga acaattgtag atcttcatct
    24061 cgaacacctt ggagaagttc aggatgccac tgaacaccta aaaaaggaat ggcatcgttg
    24121 gttgatatga ctgcttcgat ggtaccatca cgtggatccc tagcgattac ttttaaatcc
    24181 ttagcaacag tttttaaact ttggcgatga aaagaattaa ttaatgtctt atgaccataa
    24241 ataggatata agatagagtc tggctcaata atcatttcgt gtgataagaa atcagaaggc
    24301 gcttcttgcc aatgtgagtc aatgtgttgg ttaagatttc ctcctaaggc aacattcatt
    24361 aactgtgtac cacgacaaat ccctaagatt ggttttttta atgttatagc ctccttgatg
    24421 atagctagct caaatgtgtc tcgctctggt gaaaaatcat catcaaaagc agccttctct
    24481 tcttgataat attttgggcc aacgttttgc ccaccaatta aaatgatttt atcaaccata
    24541 gatacataag ttttagcggc ggcttcatca ccaatgggta aaagaagcgg cagcccccca
    24601 gattgagtga ctgcctgtac aaatccagta ggtgcatatg accatgggag attatccaaa
    24661 gccatattta gtctttgatt tgcagttatt ccaataatcg gtttggtcat tatacctcct
    24721 taatctagat gattttgatt cataaaatag agtagtgtct ggagctcact ggtcaaatcg
    24781 acagattgaa caataactcc tttaggaact tgtaggtgaa caggagcaaa actcaagatt
    24841 cctttgattc ctgcttcaat aagttgatca gtaacttctt gagcatgaat gctgggaacc
    24901 gttaagatag ccgtttcaat gtcagtgttc gcaatccgtt ctttgacgga tgagatacca
    24961 tggactggaa tattatcagc tgttttagta ccaacaagag cgttatcatc ggtatcaaaa
    25021 cccatggcaa tttgcatctt attacgatca tggaagcggt aatgtaatag agcacgccct
    25081 atattaccgc atccaactaa gataacgttt gttgtagagt gatcattaag caagtcagca
    25141 aaaaaattca tcaatttggt aacatcatag ccaaacccac gacgccccaa ttctccaaaa
    25201 taagaaaagt cacggcgtac agtagcagag tcaattccca ttgcatctgc aatttgttta
    25261 gaactggctt tttcaacttg gtcagcatgg aatcgtttaa aaatacggta ataaagtgat
    25321 aagcgctttg cagtcgcttt tggaatagat ttgtcaataa ccactatttt actccttgta
    25381 gatttctcgt taaatatgtc tgtctttatt gtaacaaaaa gattgtgaaa aatgcaacat
    25441 tttgattgtt tttgtatgag ttaaaaaagc taaaattagt tttagcacta tataatagta
    25501 ttcattagga aagtaagtta tgacagtcga aatgaacaac atgaattaat agcaatagaa
    25561 gcgaaatcat ttattgacat tgtgatatga ctaaaaaaaa acaaaattta aagttgatta
    25621 gacgactgtt ttgctaaaaa tttcacgttc tacaaggctg tccatcaaga aataaaattt
    25681 atcttgaagg atttgattat cttttgtttt aaaaatatta actaatctaa gaccagattg
    25741 atcggtgata gctaatttaa aacctgtgag ttctttatta atagtgattt ttaaagggaa
    25801 accatcccct gaattaggta ttttttcgag taaacgtatt aattggtagt gccctacttt
    25861 agtttgacta aatgtagtat ctcttagggt atatttttta atgtttggac tgattgtata
    25921 aaggtattta cagtctttaa gcttaatttc tttttcaaaa gccatctgtt cctcctaaaa
    25981 tattttttaa tgtttgagct aattgattaa catcttcaat gctattttga tctgaaaaac
    26041 tgatacgaat tgattctttt aaacgagaag agtcatcccc atagtacgca gctaaaacat
    26101 gacttggatt aacagctcca gcagtacaag cagaaccagt tgatactgca atgcctgcta
    26161 agtcaagttg tgttagtaaa atagtatttt ggtagcctaa aaatccaata ttgagaacat
    26221 gaggaagata atgagtacct tgattaatat agtagggtag tccttctagg aggctaatca
    26281 agtgatgacg taaacagata atgtgatcag ttgattggtc aagacaagtc atagcatcag
    26341 tcaaagcttg tgccatacca ataataccta acatattttc agtacttgcg cgtcgctttc
    26401 cttcttgatc acccccgtga agaagagggt cgattggttg tccgttactg tataaaaagc
    26461 cgcatccttt aggaccatga aatttgtgag cagaagcaga taaaaagtca atcccaagtt
    26521 cgctaggaat aatcttgagt ttgccaacag cttgaacggc atcaacatga aaagcagctt
    26581 gatggtcttt gagcagattc ccaatgtcct taataggtaa caggtcacct gtttcgttat
    26641 tggcatacat tatgcttacc aaaatggtgt catctctcaa ggcttgtttt aagtcagata
    26701 aatttatttg tccattttga caaggcaaat aagtgacctc aaaaccaaat cgctcttcga
    26761 gataggccat ggtatgaagc acagagtggt gctcaatagt agttgtgatg agatgtttgc
    26821 cctttgcttg atgagctaaa gcatagcctt ttatggccat attattgctt tcagttccac
    26881 cggacgttac tataatttgc tgttcacttg cccccaagtt tctagcgata gcttgtcggc
    26941 attcacgaag gattttattg gctcggcgcc cgtagaaatg aatactagag gggttaccaa
    27001 agttatcttg catagctgct gtcatcgccc taatcacatt aggactaagt ggtgtggtgg
    27061 cggcgttatc aaagtaagtc atgcgttatt tttgccttta ggttgataag aaaaaagtgg
    27121 acttaagggt cttctttcat ggatacgaat aatagcttct gcgattaaat cactggcgct
    27181 aagataagta acgttttctg gcacacgatt tttagtttta acagaatctg taacgataat
    27241 ttctttgatt ggagctgttt ctaatacctc agcagctcca ccagcaaata agccatggct
    27301 agcgaccgcg taagtatcag tagcgcctga gcgttcaaga attttagcag cttctgcaaa
    27361 ggttttccca gtatttaaaa tatcatcaat taaaatggct tttttaccag agacatcacc
    27421 aataatataa ccttgttcac gttcagaatc atcttgtgca tagtcgataa tagcaatcgg
    27481 ggaatcaaga tattcagcca agcttctagc acgtttaatt ccagaatttt tagggctaac
    27541 gacaacaaca tcagaacctg ataagcctaa tttactgtaa cgttctgcaa aaagagggac
    27601 tgtaaagagg ttatccactg gaatatcaaa aaaaccttgt acctgaacag catgtaagtc
    27661 aagcgtcact acacgatcaa taccagcttt agtcagcata ttagctacta gtttagcagt
    27721 aatcggttcg cggggcttag cgacacggtc ttgacgagag taaccaaagt atggcaatac
    27781 aatattgacg gtattagcac ttgcacgttt acaagcatca atcatgatga gtaattccca
    27841 aagattatca ttgacaggaa aactagtgga ttgaataata tagatatcat ctccacgcac
    27901 tgtttcttca atattgatca taatttctcc atcggaaaat tgacgtgaag acatttttcc
    27961 aagagggatt ccagcagctt tagcaatttt ttcagcaatt ggaagatttg atgtgagtga
    28021 gaacagtttg atttgcttgt cagcatatcg ttcagtcatg atagatttag ctccttaact
    28081 tcaataaaat tgggtaaact gttttattaa tgagtcacat tacccaaaag tgtttaattg
    28141 acatccctat tttaacagaa aaacagaaaa atttcagttt ttctgtcgct tttagccatt
    28201 atttatcgtt gaactttttt aaggtgttaa tacaccgagc tactttgctt ttagcatatt
    28261 tgaaagcaat gtgatgttca gataaaaaag aatcaaaatc aatctttcct tgaagagcgt
    28321 cacttacttc taattctaat tcatagtctt tggtattggc atataggtta tagtctaagg
    28381 ccaatttacc tatcggtatc actgtctcgc gacgaacggt agttaaattg ccaaaagtta
    28441 ccagtgcaga tggtttgata ccttttgaaa taataatatc aagagcagtt gattcaggaa
    28501 gattcccatg tttaatcata tcttttgctt gttcaagaaa aagagggaca ttgtactcac
    28561 gattccccac tttttctggc acttttaagg ttaattcggc gctatttgca aatgttcgaa
    28621 tacgtaatga cattttgtta gcttttaaat caaatgcttt tgtatcaata tagtaattag
    28681 tttgtgtaac aggcgtcaca tgtttcattt gagataaaag acggttatac tcattttttg
    28741 taagtagagt tttatattcg atttctaggt tagtcatggg aaattccttt taatttgtgc
    28801 tataataaat tgttatttca attttatatt attatcctgg ctttgacaag aaaggagaca
    28861 atagatgacc ttagattggg aagaattttt agatccttat atccaaacag ttggtgaatt
    28921 aaaaataaaa ctacggggta ttcgcaagca atatcgtaag caaaatcgtt attctccgat
    28981 tgaatttgtt acgggacgtg ttaagtcaat tgaaagtatt aaagaaaaaa tgattttacg
    29041 tggtgttatt gaagaaaata tagcacaaga tattcaagat attgctggac tacgtattat
    29101 ggttcagttt gtcgatgatg tggaagaagt cttagctcta ttgcgtcaac gacaagacat
    29161 gacaattgtt tatgaacgag attatattcg caatatgaag tccagtggct acaggtctta
    29221 tcatgtggtg gttgagtacc ctgttgacac cattgaaggt caaaaaaagg tcttagcgga
    29281 gattcagatt cgtactttgg caatgaactt ttgggcgacc attgagcatt ctttaaatta
    29341 taaatatggt ggagacttcc cagaagaaat taaaaagcgt cttgaagtga ctgctaaaat
    29401 tgctttagaa ttagacgaag aaatgcgtaa gattcgagaa gatattcggg aggctcaatt
    29461 attgtttgac cccgtgacac gaaatttaag tgatggtgta ggaaatagtg atgacacaga
    29521 tgaattatac aggtaaggta aagcgagttg ctattattgc aaatggtaag taccaaagta
    29581 aacgcgtcgc ctccaaactt ttctccgtat ttaaagatga tcctgatttc tatctttcaa
    29641 agaaaaatcc ggatattgtg atttctattg gcggagatgg gatgctctta tctgcctttc
    29701 acatgtatga aaaagaatta gataaggtac gttttgtagg aatccacacc ggtcatcttg
    29761 gcttttatac cgattatagg gattttgaag ttgataaatt gattgataat ttaagaaaag
    29821 acaagggaga acaaatctct tatcctattt taaaagttgc tattacttta gatgatggtc
    29881 gtgtggttaa agcgcgtgct ttgaatgaag cgacggttaa gcgtattgaa aaaacgatgg
    29941 tagcagatgt tattattaac catgtcaaat ttgaaagctt ccgaggtgat gggatttcag
    30001 tatcaacccc gacagggagc acagcctaca ataaatcttt aggtggtgct gtcttgcatc
    30061 cgacgattga agcgctgcaa ttgacggaaa tttccagtct taataaccgt gtctttagaa
    30121 ccttgggctc atcaatcatt attcccaaaa aagataagat tgagttagtg ccaaaacgat
    30181 taggaattta taccatttcc attgataata aaacctatca gttaaaaaat gtgacgaagg
    30241 tggagtattt tatcgacgat gagaaaattc attttgtttc ctctccgagt catacgagct
    30301 tttgggaaag ggtcaaggat gcctttattg gagaaattga ctcatgagat ttgaatttgt
    30361 agcagacaaa cgaataaaag taaaaaccct tttaaaaagt catgatgtct ctaaaggact
    30421 attggctaaa atcaaatata agggtggtaa tatattagtg aatggtattg aacaaaatgc
    30481 catttattta ttgcaagtgg gagatgttgt caccattgac attccaaacg aagagccctt
    30541 tgaaaagctt gaagccatcc cttttgattt ggatattgtt cacgaggatg atcatttttt
    30601 ggtgattaat aaacccattg gctttgccag tattccaagt gccatccact ccaataccat
    30661 tgctaacttt atcaaggcat attatgtgga caatcattac ctagaccaac aagtacatat
    30721 cgtgacccgt ttagacagag atacgagtgg cttgatgtta tttgctaagc atggttatgc
    30781 tcatgcaagg ttggacaagc aactccaaac tcgctcaata gagaaacgtt attttgctct
    30841 ggtttctgga aatgggacgt tgccagatga aggagatatt attgctccaa ttgggcgttc
    30901 aaaagatagt attattacca gggcagttga ccctatgggc aaatatgcca agactagcta
    30961 taaggttgtg gcgcgctatt cagaaaatgt gcatttagtg gatatcaaat tgcatacagg
    31021 acgtacccat caaatcaggg ttcattttgc ccatattggt tttccacttt taggggatga
    31081 cctttacgga ggtcgtttgg acttaggaat aacaaggcaa gccttacatt gtcattattt
    31141 gaatttcaaa gatccattta cagaaagtga ttgtagctat gcaatacact tgacagatga
    31201 ctttgatagc gttatcatag gtttacagaa aaaagataga ggttattaaa gaatgagtat
    31261 tcgtagttta ttcggtggtt taagagaaaa aattcttggt aaaaacatga agattgtttt
    31321 cccagaaggt aatgatgagc gcgtcgtccg tgcagctgct cgtttgaaat ttgaaggact
    31381 cttagaaccg attatccttg gacagtcaga agaggtacgc aaccttttga caaaattagg
    31441 cttcgctgat caagactata ctatcattaa tccaaatgaa tatgcggatt ttgacaaaat
    31501 gaaagaaact tttgttgacg tccgtaaagg aaaagcaacg cttgaagatg ctgataaaat
    31561 gcttcgtgat gtgaattact ttggtgttat gttggttaaa atgggattag cagatggaat
    31621 ggtatctggt gctattcatt caacagctga tactgttcgt ccagcccttc aaatcattaa
    31681 aaccaaacca ggtatttcaa gaacttcagg tgttttcttg atgaatcgtg aaaatacgag
    31741 tgagcgttac gtgtttgctg attgtgctat caatattgac ccaacagcac aagaattggc
    31801 agaaatcgct gttaacacag ctgaaacagc taaaatcttt gatattgatc ctaaaattgc
    31861 tatgttaagc ttctcaacaa aaggttctgg taaagcgcct caagttgata aggtaagaga
    31921 agcaacagaa attgctaaag ggttgaatcc tgacttagct cttgatggtg aattgcagtt
    31981 tgatgcagcc tttgttcctg aaacggcagc tatcaaagca ccagattcag cggttgctgg
    32041 ccaagccaat acttttattt tccctgactt acaatctgga aatattggtt acaaaattgc
    32101 acaacgttta ggaatgtttg atgctattgg accaatctta caaggattga acaaacctgt
    32161 taatgattta tctcgtggct caagcgctga agatatttac aaattagcta ttattacagc
    32221 agcacaagct atcgaaagcc aagggtaact taagacccct tgatatagga ttctaaccgc
    32281 taagtgatgt gttagaagtt gtcctaagac taattgacat tattaaaaac gagttggcca
    32341 gaccatctcg ttttttttga aggtgaggaa atgtatggga aatattgcct tagtaacagg
    32401 ggcttcagcc ggttttggca gagccattgt cgaacactta attgcagatg ggataaaggt
    32461 tattggtgct tctcgtcgtc ttgagaaact caaggtctta gaaacgagct ttgggtcgga
    32521 caacttttac cctttgcaga tggatgtcac agataccaaa gcgattgatg atgctttgac
    32581 aagtctacca aatcagtggc aagatattac tattttagtg aataatgcag gcttagcatt
    32641 gggacttgat aaggcttatg aagccgattt tgagaattgg atgacgatga ttaataccaa
    32701 tattgttggg ttgatttatc tcacacgtca attattacca catatggtct ccaaagatga
    32761 tggtattatt attaatttag ggtcaaccgc agggacaatt ccctatccgg gagctaatat
    32821 ttatggggct agcaaggctt ttgttaagca gttctcactc aatttacgag ctgatttagt
    32881 aggtagccat atacgtgtga ccaatattga acccggtcta tgtgaaggga cagaattttc
    32941 aaaggttcgc tttaatggtg atgaggaacg ggtgaaggcc atttatcaag gagcacatgc
    33001 cattcaacct caagatattg cgtcgactgt atcatgggtg attcatcagc cccctcatgt
    33061 taatgttaat cgtattgagc tgatgccagt gtcgcaaagt tatggaccgc aaccagttag
    33121 tcgtgactag caagggatga gtccataaga ataataatct ttagaaaaat ggtttactgg
    33181 tatggattat tctttataag tgagacttac cgatttagtc atcaaaaaaa gcaattaaga
    33241 agaaggtttt gaggtcttca agcgttcatg attgcttctt gtgcgttgat gatttaggct
    33301 gaactcccta tttaaaatca agtttagtga tctaaaatgg aagggcctga tgtgatatcg
    33361 gaccagccaa caatggcttg tccagtttct tctaaatacc ggtttaataa cggtttaatg
    33421 tcttgaacgg tatccaaaac tcccaccagc tgaccttgag gatttttaag agcttgataa
    33481 tgctgcatgt aaatatgatc caatgaaccc gaaggaagta ggaaggtttt acaagggtta
    33541 tctgataaac gcaattcagc aagaatccaa tcttctattt ctttatcagt agttggcaaa
    33601 aaacttccat taaaagcatg attatcgact atgatgtttc catttgcatc agataacctt
    33661 gcttgcaaag gaagatactg taaaaaatgt ccatcaaatt tttggtaaaa tccagtgagg
    33721 tattggctta acgataagac tgctgttgct tgatcaaaga cactttctgt cactaaaaag
    33781 ccctgaccat gttgagaagt tttgaaatag agtgtaggca agtcaatgtc atgctcatgg
    33841 aaactgaaaa ttccttggaa agtcgacaat tgatttgact gaatgttggc tttgctagtg
    33901 agaatagtca cctcaaaaag gtgtgagaag tggtgggaaa gctctctaat aaacgtctct
    33961 tcaagttggt tttcaggtgt taagagcgct aaaatggaac tggcattttt cataattgta
    34021 tgatagctgt attttctaga aaagacaatt aatctgctta tctatcatca taggcaagtc
    34081 taggattttt gataaggtaa ttttggagag ataggctgac ccagtgacct gtttttctat
    34141 aagggggtaa tagtctcatt atttgactta tagtgggaaa ctttttataa tggtcaacaa
    34201 caaacgacaa gaaaataatg agagaaaatg tttttgagaa ttggtagttt ttaccttact
    34261 gaggacacct aagagtccct ttaattagta gatgcgtttg tctaaaaatg gtagggcatg
    34321 cagtgattcc ttgtagttac tcagaacgtt ttgagaaaaa atgacagaga gacaggttga
    34381 atgaactcat cagcttttat gctgttactt taaccaatga attggagaaa taatgatacg
    34441 ttttaataat gtttctaaaa cttttggtca gacaaaggtt ttgcaagagc agacctttca
    34501 aattaatgac cgtgaatttt ttgtgctggt tggccccagc ggatcgggga aaaccacact
    34561 tttaaaaatg attaactgcc ttattgaacc aagctctgga gatattttac tgaataacgt
    34621 cccacagaaa gagttagatt tacgtgagat gaggctatct attggatacg tgttgcagca
    34681 aattgctctt ttccccaatc tcacagtagc tgaaaatatt gcgattatcc ctgatatgaa
    34741 gcaatggtca gctgaagaaa ttagacaaaa aactgaagaa ttattggata aggtgggcct
    34801 acctgctaaa gattatcttg atcgttaccc aagtgattta tcgggaggtg aacagcaacg
    34861 tattggtatt gtacgtgcta tcatttctca tcctaaaatt ctattgatgg atgaaccatt
    34921 ttcagcctta gatcctattt cacgtaaaca attgcaagag ttaatgttga gtcttcacaa
    34981 ggaatttgac atgacgattg tatttgtgac acatgatatt gatgaggcca ttaaattagg
    35041 agaccgcgta gctattttaa atgagggaga aattgtgcaa ctggatcgcc cagaaatgat
    35101 taagacccac cctgctaatg cttttgtggt caatttattt ggaggtgatg agcatgccta
    35161 gtttgtttgt aactttccaa aaccgtttta atgaatggct ggcggctctg ggggaacacc
    35221 tgcaaatttc ccttttatct cttatgatcg ccttgctaat aggtgtgcct ttagcagccc
    35281 ttctcagtcg cagcaaacgt tggtcagaca ttatgttaca ggtaacaggt gtttttcaaa
    35341 ccattccctc actggctttg cttggtcttt tcatcccttt aatgggaatt ggaacgttgc
    35401 ctgcagtgac agctttagtt atctatgcga tttttccgat tttacaaaac accatcacag
    35461 gattaaatgg tattgaccca agtctcgtgg aagcaggaat agcttttggg atgaccaaat
    35521 gggagcggtt aaaaacgttt gagattccaa ttgccatgcc tgtcattatg tcaggtgtgc
    35581 gaacgtcagc agtcatgatt atcggcacag ctactttagc ttccttgata ggagccggtg
    35641 gacttggctc tttcatctta ttggggatcg atcgtaataa tgctaacctg attctgatag
    35701 gggctatttc ttcagctctg ctagctatta ttttcaatag tttgttacag taccttgaga
    35761 aagcttcctt gcgacggatt atgattagtt ttggaatcac cttacttgca ttgctagcat
    35821 cgtatactcc tatggcgctt agtcagtttt caaaaggaaa agatacagtg gttattgccg
    35881 gtaaattggg agcagagccc gatattctga ttaatctcta taaggaatta attgaagacc
    35941 aatcagatat aagcgttgag ttgaaatcta attttgggaa aactagcttc ttatatgaag
    36001 cccttaaatc tggagatatt gatatctatc ctgaatttac aggaactata acatcaagtc
    36061 ttttacgcga caaaccaccg ttgtctaatg accctaagca ggtctatgag gatgctaaaa
    36121 aaggcattgc taagcaagat aaactgaccc ttcttaagcc atttgcttac caaaatacgt
    36181 atgctgttgc tatgccagaa aaattggcta aggaatatca gattgaaacc atttctgatt
    36241 taaaagcgca tgctgatact ttaaaggctg gttttactct ggaatttaag gacagagcag
    36301 atggctataa gggaatgcaa tctcaatatg gattacagct atctgtggcg acgatggagc
    36361 cagctcttcg ttatcaagca attcaatcag gagatatcca agtaacagat gcttactcta
    36421 cggatgctga aattacgaaa taccatttga aagttttaaa agatgataaa cagttgtttc
    36481 caccttatca gggagctcct ttgatgaaaa cttccttatt aacaaaacat ccagaattaa
    36541 aaggcattct taatcaatta gcgggaaaaa ttactgaaaa agagatgcag gacatgaact
    36601 acgaggtatc tgttaaagga gcagatgcta ataaggtcgc tcgagattat ctgttgaaaa
    36661 caggcttaat ccagaaataa acagaaatgt tggtccgcag gactggcatt ttttcgtctc
    36721 ttaagttcaa gaagtaacaa ttcataaata caaaaaccga actttaaaat taaaaatagc
    36781 atataaattt gacaaaatat aaacaaataa gtaatctata aaatgaaagg taagttttta
    36841 cctaaagata cctctaatca tcagaggtca taggaagatt attttgtata gaggacttag
    36901 agaagaaggt gagaactgac ttattttctt tcatctgtgc taaaagagga gaaacttatg
    36961 tttaatgaca tccctgtatt tgattatgaa gatattcaac tgattcctaa caagtgcatt
    37021 attactagtc gttcacaagc agatacaagt gtgacactcg gaaaatacca gttcaagcta
    37081 ccagttatcc cagcaaatat gcaaaccatt attgatgaaa caattgctga gcagttggca
    37141 aaagagggtt atttttatat tatgcatcgt tttgatgaag atagccgcaa accttttatc
    37201 aaacgcatgc atgaacaagg cttgattgca tccatctctg ttggggttaa agcttacgaa
    37261 tatgaatttg tgacttcttt gaaagaggat actcctgagt ttatcaccat tgatattgct
    37321 catggtcatg ctaacagtgt tattgatatg attaagcata tcaaaactga attaccagaa
    37381 acatttgtca ttgctggaaa tgttggtacg ccagaagctg tacgagaact cgaaaatgca
    37441 ggtgctgatg ctactaaagt aggcatcggt ccaggcaaag tatgtatcac taaagttaaa
    37501 acaggtttcg gtacaggtgg ttggcagtta gcagcactgc gctggtgcgc aaaggcagct
    37561 cgtaagccta tcattgctga tggtgggatt cgcacacatg gtgatatcgc taaatccatc
    37621 cgctttggag ctagtatggt catgattggt tcgctttttg cagggcatat tgaaagtcct
    37681 ggaaaaacag tagaagtgaa tggtgaaacg tttaaagaat attatggctc ggcgtcagca
    37741 tatcaaaaag gcgagcataa aaatgtagaa ggcaaaaaaa tcttattgcc tacaaaaggt
    37801 cacttatcag ataccctgac cgaaatgcaa caggatttgc aatcgtccat ttcttacgcg
    37861 ggtggtaaag atttagacag tttgcgtcat gttgattatg ttatcgtcaa aaattctatt
    37921 tggaatggtg attccattta aatgatatgg agttagctag gaccagtaaa gaatttttta
    37981 gcttaatgct ggagatgctt ttatcatatc tctgtaggta ttgaaaaaaa taagaaacat
    38041 ggtaaaatag taaattatca taatgaattc aataatgaca tacttattta tgctgtgaat
    38101 tggcgcagcg tctctacaag acaccttaat gtctaacaat aagtaagctt ttaggcttgc
    38161 ttggttttta accttgcaaa gtgagaaact cttatagttt ctggctttgc ggcaggcttt
    38221 ttctatttga atcaaaagga gatttatgca gttacttgaa gaacgcatct taacagatgg
    38281 caatattcta ggagagaata ttttaaaggt agataatttt ttaactcatc aagttgatta
    38341 ccggttgatg aaagcaattg gtaaagtgtt tgctcaaaaa tatgctgagg ctggcattac
    38401 aaaagtggtt acaatcgaag cttcaggtat tgcaccagcc gtatacgctg cagaagcaat
    38461 ggatgttcct atgatttttg cgaaaaaaca taaaaacatt accatgacag aaggcatttt
    38521 gacagcagaa gtttattctt tcactaaaca agttacgagc acggtgtcta tcgctggtaa
    38581 attcctatct aaagaagaca aggttttgat tattgatgac tttttagcta atggtcaggc
    38641 agccaaaggc ttgatcgaga ttattggtca agcaggggca caagtcgtcg gcgttggtat
    38701 tgtgattgag aaatctttcc aagatggtcg tcgattgatt gaagatatgg gcattgaagt
    38761 gacctcatta gcacgtatta aaaactttga aaatggtaat ctaaacttct tggaggctga
    38821 cgcataatga cacattcaac aaagcaggaa cattctcact cgcaatcagc tgtccttggc
    38881 ttacagcatg tgctttcgat gtatgccgga tctattttag taccaattat gatcgcaggt
    38941 gctttaggtt attccgctag agagttgacc tacctgattt cgacagatat tttcatgtgt
    39001 ggtgtggcta ctttcttaca gttaaagtta accaagcata cgggagtggg attaccagtt
    39061 gttttaggat gtgcttttca atcagtggca cctctatcca ttattggagc gcaacaaggt
    39121 tcaggtgcca tgtttggagc cctcattgcg tcaggaattt atgtcatttt agtggcaggt
    39181 attttttcta agattgctcg tttcttccca ccaattgtta caggatcggt cattaccgtt
    39241 attggcttaa gtctcgtagg tgttgctatg gggaatatgg gagataacgt caaagagcct
    39301 acggcacaaa gcatgatgtt atcattgttg acgattgtca ttattctttt agtccaaaaa
    39361 tttaccaaag gttttgtgaa atccatttcc attttgattg ggcttgtagc gggaactttg
    39421 gtttcagcca tgatgggatt agtagataca actcctgttg tagaggcttc ttggattcat
    39481 gtgccaaccc cattttattt tggcatgcca acttttgaaa tcacttctat tgtgatgatg
    39541 tgtatcatcg caacggtttc tatggttgaa tcaacaggtg tctacttagc gctttcagat
    39601 ttgactaatg atcaattaga tgaaaaacgt ttgcgcaatg gttatcgctc agaagggatc
    39661 gcagtctttc tcggtgggtt atttaatacc ttcccttaca ctggtttttc tcaaaacgtt
    39721 ggacttgtcc aaatctcagg tattaaaacc cgtcgtccga tttactacgc agcaggtatc
    39781 cttgtggtca ttggtctact ccctaaattt ggagcaatgg cacaaacgat tccaagccca
    39841 gttcttggtg gagccatgct tgttctcttt ggtatggttg ctcttcaagg aatgcaaatg
    39901 cttaatcgtg ttgatttcca aaagaacgag tataatttta ttattgctgc cgtttccatc
    39961 tcagcaggtt taggctttaa tggcactaat ctttttgcca gcttaccaga gacagctcaa
    40021 atgttcttaa cgaatggtat tgtgattgcc actttgacat ctgttgtctt aaatttagtt
    40081 ttaaatggca aagacaaaca agatgaataa ttaaaaaacg gctaattgag ccgttttttc
    40141 tgtgatcagt tttgagcaaa ccgttaaccc cttttaatga tagtatggtt gaaaatagtg
    40201 tctcaaacca tttgacataa ggacatggtg ctttcttgtt actagaagac cttcaatatt
    40261 atcaaaggta tttaaaagtg tgataatcat tgagctatca agaccaaata aacgggtagt
    40321 ccatatgtca caataaaaag aagaaggagc catgatcgtt aagctaagca tatctgtttc
    40381 tatagggtag cctgtctgac gatctaagat atgatgatac tgtttccctt tggatgtaaa
    40441 ctgcctttca taaattccag aagtcacaac agagtgattg ttaaccttga tgacaccaag
    40501 atgttgccca cgtttagcat ctggtttttg aatgccaatt cgaaaagtct tgtcagggct
    40561 tttcggatta ggtccatgaa cgcgtacatt tccacctaaa ttaataaggg cagagtcaat
    40621 accatcttca atcaggtagg ccataatctt atcagtaata taaccttttg ctaaggctcc
    40681 taagtctaaa gccattccta cttgttgtaa aaagacagtc tgttttttgt catctataag
    40741 aacctgtcta ggatctgtta gagctaactg ttgtgagata aggttatgac taggcactct
    40801 agcatcttca aatccaattc gccaggcttg aacaagtggc ccaatggcga tattaagatt
    40861 acttggtgtt gacaagctat gagctttacc aatttggact aggttaaata aatcagagtg
    40921 aacgctgacg ggtttaacac cagccgcctg attaatagcc atcaattcag agtttgaatc
    40981 attagctgaa aaacgatttt tgtaagtata taataagtca atgactctac ttagttgttg
    41041 gcaagctttg tcagattcga tctgaatatc aataactgtt cccattagct ttaattgttg
    41101 cgtaacaaac ataattagtc ctctttttag cagaataccc ccactaagga gtgggggaag
    41161 gtcattatga tttttgtttc atttcacctt gaggatagta agttccttca ggcatatcgt
    41221 tgataaaaac atggatattt tctttaggtg cttttgcaat gcgtgagact acttcggtaa
    41281 cctcgcgagc taattgattt ttttgttctt gtgagcgtcc ctcaaacaag tcaattgtta
    41341 caaatggcat aatgttactc ctttatgtta ttgggcatca ttgtaacata atgctgtgaa
    41401 aaagtacaca ctgttttcaa tggctgggaa aacttcagcc tttgtggtaa aataggtaga
    41461 atactataga aagtaggatt ttccgctttg gctcaactct attataaata tgggacaatg
    41521 aattctggta aaaccattga aattttaaaa gttgctcata actatgaaga acaaggcaaa
    41581 cctgttgtca ttatgacaag tgctcttgat acacgtgatg gttttggcat cgtctcaagc
    41641 cgtattggta tgcgacgaga agctattccc atttcaaatg acatagatat tttcacattt
    41701 attgcccaat tggaagaaaa accttattgt gtcctgattg acgaaagtca atttttaagc
    41761 aagcaaaatg tttatgattt ggcgcgtgtg gtggatgagc taaatgttcc tgtcatggct
    41821 tttggtttga aaaatgattt ccaaaacaat ctttttgaag gttcaaaaca tttgctatta
    41881 ttggccgata agattgatga aatcaaaaca atttgccaat actgtagtaa gaaagcaacc
    41941 atggttttaa ggacagaaaa cggaaaacct gtctatgaag gtgatcagat acaaattggt
    42001 ggtaatgaaa catatatccc agtttgtcga aaacattatt ttaatccaga gatttaaaag
    42061 gtaatcggtt ttaaaggaga tacaaagaaa aatgaatatt tatgatcaat tgcaggcagt
    42121 cgaagatcgt tatgaagagt taggtgagtt acttagtgat ccagatgttg tttcagatac
    42181 aaagcgattt atggaattat cacgtgaaga agctaacact cgagaaactg tcacagctta
    42241 tagagaatat aagcaagtca ttcaaaccat ttcagatgct gaagaaatga tcaaagatgc
    42301 cagtggtgat cctgaattag aagaaatggc taaagaagaa cttaaagaat caaaagcagc
    42361 taaagaagag tatgaagaaa aattaaaaat ccttctatta cctaaagatc ctaacgatga
    42421 taaaaacatt attttagaaa ttcgtggtgc tgctggtggc gatgaagcag cgctttttgc
    42481 tggtgatctt ttaacaatgt atcaaaaata tgctgaaact caaggatggc gttttgaagt
    42541 tatggaatca tccgttaatg gtgttggtgg tattaaagaa gtggttgcca tggtttctgg
    42601 tcagtcagtt tattctaagc ttaaatatga atcaggagct catcgtgttc aacgtgtccc
    42661 ggtgacagag agtcagggtc gtgttcatac gtcaactgca actgttttgg taatgccaga
    42721 agttgaagaa gtagaatacg acattgatcc taaagacctt cgcgtcgata tttaccacgc
    42781 gtctggtgct ggtggtcaga atgtcaataa agttgctact gcagttcgta tggtacacat
    42841 tcctacagga atcaaagttg aaatgcaaga agaacgtact cagcaaaaaa accgtgataa
    42901 agcgatgaaa atcattcgtg ctcgtgttgc tgaccatttt gcgcaaattg ctcaagatga
    42961 acaagatgct gaacgtaaat caacagttgg tactggtgat cgttcagaac gtattcgtac
    43021 ttataatttc ccacaaaatc gtgtaacaga tcatcgtatt ggtttgacac ttcaaaaatt
    43081 agatactatt ttatctggaa aaatgaatga agttattgat gcactcgtta tgtatgatca
    43141 gacaaagaaa ttagaatctc tcaataacta atgaactatg ctacattaat cagaacttat
    43201 gaagataaac tagaacaaat agatgaggat cgcgaaaatc tcgcctatgt ttttagcgaa
    43261 atcaaagaat ggtcaagtct agatatgttg attcaccaaa atcaagctgt gactcctgaa
    43321 gatgctgttc ttttggaaca tattttctgt tctctaagtc agcatttatc tcctcaatat
    43381 attacaggta atgcttattt tcgtgatttg aagcttgcag tcgacaagcg tgtattaatt
    43441 ccaaggccag aaacagaaga attagttgac atgattttag ctgaaaatct tgatgcaccg
    43501 ttgaatgttt tagatattgg tacaggtagt ggagcgattg ctatttctct caaaaaagaa
    43561 aggcctaact ggcaagtaac ggcatctgat atttctagag ctgctcttga cttggcaaaa
    43621 gccaatgctg atgcttacca gcttgatata acgtttattg aatcagatgt ttttagtctc
    43681 atttcaggaa cctttgatat tattgtgtca aatcctccct acatatccta cgaggataag
    43741 gaagaagtca gtctaaatgt tttgcaatca gagcctcatt tggcactttt tgctaaagaa
    43801 aatggctatg ctatttaccg taagattatt gaacaagctg acaattactt aactaaggag
    43861 gggaagcttt actttgaaat tggttataag caagctgaag gtataaaaga tatgttacaa
    43921 gcctattttc ctcaaagaca tatacgagtc gtaacggata tatttggcaa agaaaggatg
    43981 gtggttgttg attatggagt atctagctag tatcattgaa tcaggtgatg cccttgtttt
    44041 gccaacagaa acggtttatg gtctttttgc caaggcttta gatgagaaag cagtaaatgc
    44101 tgtttatgac ttaaaacaaa gaccccgaga taaagcaatg aaccttaatg tggctgattt
    44161 taatagtatc ttagcctttt caaaagaaca gccgagatac ctcaagaaat tataccaagc
    44221 ctttttacca ggtccgttaa cgattatttt aaaagctaat gaccaggttc cttattggat
    44281 taattcgggt ctttcaacgg ttggttttcg cttacccagt catccaatta ccgcagcttt
    44341 aattcaaaaa acaggccctt taattggtcc ttctgcaaac ttatctggca aagctagtgg
    44401 tcgagttttt gatcatatta tgcaagattt tgactttcaa gtgtttggtt atgcagatga
    44461 tccttttcta acaggtaagg attcaaccat cttagactta tcaggtgagc gtgctgtgat
    44521 tttacgtcaa ggtgctatca ccaaagaaga attattagcc aacgtgcctg aacttcgctt
    44581 ttaagagagg agccgcttgg aatgttgaga ccattaagta aaacggactg tcctatgcta
    44641 caagaaatta acgccaaagc ccttggctat ttagtttcgc ttgacttgtt agaaaggcaa
    44701 tatgaacgat tgattgagga ttgccatcac tattttttag cttatgccga caaggatacc
    44761 aatcaattat taggctatgt tcacgctgaa cggtatgaga ccctttatgc ttctgatggt
    44821 cttaatctct tgggcttggc tgttttacca gcctatcaga gaaggggaat tgggagtgcc
    44881 ttactaaggg ccctggaatc ccaagctaag caggaaggca ttgcctttat tcgcctcaat
    44941 tctgccagtc atcgtaaaga agcacatgct ttttaccaaa acctcgacta tgcagatgat
    45001 aaaacacaat tacgattcat caaaaactta caaggagatg acaatgattt ttgataaagg
    45061 taatgttgaa gactttgata aagagctttg ggatgccatt catgctgaag aagaaagaca
    45121 agaacatcat atcgaattga ttgcatctga aaacatggtt tcaaaagctg tcatggcagc
    45181 tcaaggttct gttttaacca ataagtatgc agaaggctat ccaggtaatc gctattatgg
    45241 tggaacagaa tgtgtggata ttgtcgaaac gcttgctatt gaacgtgcta agaaactttt
    45301 cggtgccgca tttgccaatg ttcaagccca ttccggaagt caagccaatg cagcagctta
    45361 tatggccttg attgaggctg gtgacaccgt attaggaatg gatttggctg caggtggtca
    45421 tctcacgcat ggctctccag taaatttttc tggaaaaacc taccattttg tgggttactc
    45481 agtagatgct gatactgaaa tgttaaatta tgaggcgatt ttagaacaag caaaggcggt
    45541 ccaaccaaag cttatcgttg caggggcttc ggcctactct agaagcattg attttgaaaa
    45601 gtttcgtgcc attgctgatc acgtaggtgc ttacttaatg gtggacatgg ctcacatcgc
    45661 tggccttgta gcagcaggtg tgcacccgag tcctgtccct tatgcgcata ttgtgacgtc
    45721 aacaacccat aaaaccttac gtggtcctcg tggaggcttg atattaacca atgacgaagc
    45781 tcttgctaaa aagattaatt cggccgtttt ccctggttta caaggaggac ctctggaaca
    45841 cgtgattgct gccaaggcgg ttgccttcaa agaagccttg gatccagcct ttaaagacta
    45901 tgcacaagct attattgata atactgcggc tatggcagca gtttttgcac aagatgatcg
    45961 tttccgtctg atctcaggtg gtacagataa tcatgtcttt ttagtagatg tcactaaggt
    46021 tattgctaat ggtaaactag cgcaaattct tctggatgag gttaatatta ctctaaataa
    46081 aaatgccatt ccttttgaaa ccttatctcc ttttaaaaca tcaggcattc gtattggttg
    46141 tgcagctata accagtcgtg gcatgggagt taaagaaagc caaactatcg ctcacctcat
    46201 catcaaagcc ttggttaatc ataatcagac tgttattctt gaagaagtcc gtcaggaagt
    46261 gcgtcagtta accgatgcct tcccactcta taaaaagtaa ggaatcatgt tagatagtta
    46321 tataaaacgt attgtcattc atcaattttc tcccaatgac actgagttac tgttatcaga
    46381 tcgtttagtg agcattacac cacgaattga tgaatatttc cggaaaaaat tggctaaagt
    46441 gttctcggat gaagccaaac ggggtcagtt tgaggctaat aatacctttt ttacaaccat
    46501 tggtgatgat ttgttggaaa cgtctgttac cattgcccag ttatggaagg aagcctttgt
    46561 tatttcagag gatcaaaaaa ccaatgactt agtctttgtt cagtttgata aggatggcga
    46621 cccctttttt gctttcttgc gaattgcttt gaaagaacag tttgctcacc tttctgacaa
    46681 ttatgaacat ccatttacgg tgacgcagaa taatctgccg agtcccaccc agacaccaga
    46741 tgaagcacta gtcattaatc tcaaatctgg tcagtactac ttgattgaaa agcgtgtgaa
    46801 gcataatggc agttttgcta attatttttc agaacacctc ttgaaagtta cacctgagca
    46861 atctgttaaa aagtctatca aaatgataga acaaaccgct caaaaaattg cagagcattt
    46921 taatcaagat gattttactt ttcagtcaaa gatgaaatcc actcttttta agcagttaga
    46981 agcagacgat attttatcac cagaaaaatt agctgaccaa ctctttgatg ataatttaac
    47041 agcccgttta acctttgtgg atcaagtcaa agatgtcatt ccagaaccta taaaaattag
    47101 cgatattgat cattctagac agataaaaaa actagaaaat caaaagctat cgttatcaaa
    47161 cgggatagaa ttaacagtac caaatgccat ttatcaggat gctgaagcgg ttgaattttt
    47221 gttaaatgat gatgggactt attcaatctt gattaaaaat atagaggata ttaaaaccaa
    47281 atagatgttt agacttttaa agcgtgcctg cagttttctt cttttttttg tcatttatca
    47341 atcctttgtt attcatcaca atgttcaacg tgttttggca tataagccta tggttgagaa
    47401 aacattagca gaaaatgata caaaggcaaa tgtagactta gtcttagcta tgatatacac
    47461 cgagacaaaa ggaggagaag cagatgtcat gcaatccagt gaaagcagtt caggacaaaa
    47521 aaactcgatt acagatagtc aggccagtat tgagcacggg gtgaatttac tgtctcataa
    47581 tcttgctcta gctgaggaag caggagtaga ttcttggacg gctgttcagg cctataattt
    47641 tggaacagct tatattgatt atattgctaa acatggaggt caaaataccg ttgatttagc
    47701 gactacctat tccaaaacag ttgtggcgcc aagcctaggc aacactagtg gtcaaaccta
    47761 tttttattac caccccctcg ccttgatttc tggaggtaag ctttataaga atggcggcaa
    47821 tatctattac tcacgagaag ttcatttcaa tctttattta attgaactga tgagcctttt
    47881 ttagaaagtt atcatgaaac gattacgtcc atgtgtgaaa gggtacctaa aagaaagtat
    47941 cttaggtcct ctttttaaat tattagaagc tttatttgaa ttattagtcc ctttgttagt
    48001 tgctaacatg attgatctat cgattagtca acacaacagc cagggaattt tgagggttgt
    48061 tttaacatta tttggtttag caaccattgg cttattgctt tccgttacag cccagtattt
    48121 ttcttcgaaa gcagctgttg gttttacaag acaaatgaca gatgatttgt ttaaaaaaat
    48181 catgtttttg agcaaggagg accaagacca tcttggttat gctagtctgt tatcacgatt
    48241 gaccagtgat agttttcaaa ttcaaactgg tatcaatcaa tttttgcgtc tttttctaag
    48301 ggcccctatt atcgtatgtg gtgctatggt aatggcttat tggattagtc caagtctaac
    48361 cctatggttt gtgatgatgg tgattgtttt actaacactt gtttttgtta tgtcacattt
    48421 attaggtccc ctttatctct taatccgccg agaaacagat cacttggttc gtttgactag
    48481 ccaacagtta caaggaatcc gagtaattaa ggcttttaat caaacccaaa aagaactcca
    48541 agcatttaag cagcaaaata tgctcttaag tcgccaccaa tatcaagctg ctaccctagc
    48601 caatgtcttg aatcctatga cttttttagt ggtcaatctt accctgttaa tcttgatttg
    48661 gcaaggaagt tggcaagtag ctcataggtc gcttagtcag ggcatgttgg ttgctttaat
    48721 taattacctc ttgcagattt tggcagaact tttgaaaatg accatgttga tgggaaccat
    48781 caatcaaagt gtaacagccg caaaacggat taatcaggtg tttgttttag ctgatgaagc
    48841 gcctttgccc ttacttaaag atggtcctat ttcaactcat ctgttgacca tccggcactt
    48901 gacctttact tatccaggag cagcagagcc aagtctgtat gatattcagt taagtgctga
    48961 tcagggagaa tggattggca tcattggtgg tactggagca ggcaaaacga ctttgattga
    49021 cttgatctgc caaacttatt cacaatatag tggtgaggtt agtcttaatt ggcaaggaga
    49081 agtgccaaaa acactaaccg agtggcgaaa tgtgattgct cttgttcctc aaaaagctca
    49141 attatttaaa ggaacgatta gaaataacct cctactggga caatcaatgc ctattagtga
    49201 tgaggaactg tggcgggctc ttgaattggc tcaagcaaaa gagtttgtcg ctgccttacc
    49261 agaacaatta gaggcacctg ttgaagcctt cggtcgtcat ttttcaggag ggcaacggca
    49321 acgtctagct attgtcagag cacttctgaa gccaaaaccc attttgattt tggatgatgc
    49381 cagttccgcc ttagacaatg agactcgagg acgacttttt aaagctctaa aagaagagtt
    49441 atcagacgtt ttagtgattc tagtcacgca atccatcaag aatttgcagt ttgctgataa
    49501 gattttagtg ttggaacagg gccatcaatt ggattttgcc agtcatgacc agttaaaagt
    49561 aagcaatgca ctttatcaag aaatgctagc gctttacgtg aagggggagt aaaaatgatt
    49621 aaaacagatc atcacctcct aaagcgagtg cttcaggatt tgttaaaaaa acctctacct
    49681 gtttgtattc tcgtgatcgc tagttttgta caagttggtt taagtgttta cttgcctgtt
    49741 cttattggta aagccgttga tatgagtttg tcagtcaatt cttggcaaac tttaaaatgg
    49801 ctgttggggc aaatgttagt tgttattgtg gtcaacacat tgattcaatg ggtgatgcct
    49861 cttgtctata gtcgtttgtt atatcaatat agccagcaat tgaaagataa gcttttggaa
    49921 aaaattcatc gtcttccttt tgcatatcta gatcgtcaaa ccattggaga tttggttagt
    49981 cgagtgataa ccgacactga gcaactgatc aatggtctac aaatggtttt taaccagttt
    50041 atacttggac tattgacgat tctgtgtacc attatagcta tggcacagat tgactggctc
    50101 atgttaatct tggttttggt gttaacacca agctccctct ttttagctcg ttttattgct
    50161 caaaagagtt ttcattatgc acaagcacag accaaaagca gaggaaattt agctcagttt
    50221 actgaagaaa tccttcgtca agaaggtttg gttcaactgt ttaatgctca agagcagtct
    50281 atctgtgatt atcatgtttt aaataaaacc tattgcgagg cttcacaaaa agccattttt
    50341 tacgcctcaa cagtcaatcc agccactcgc tttattaata gtgtcattta tgctttactg
    50401 gcaggtttag gggctgttcg tatcatggct ggactttttt cagtaggtca gctaaccact
    50461 tttttaaatg ttgttgtcca atataccaaa cctttcaacg atatttcatc tgtcttggca
    50521 gagatacaga gttctttagc ttgtgcgcaa aggctttatg accttttaga tattgaaata
    50581 aaagagcaag agcactttct aacatttaag gcatcagcgg ttaagggaca aattgacttt
    50641 gaagaagtaa gtttttctta tcaaaaagac aggcccttac tgaaggatat taatttttct
    50701 gttcctgcgg gttccaaggt agcgattgta gggcctacag gtgcaggcaa atcgacttta
    50761 atcaatttac tcatgcgctt ttatgaactt gatgctggta gcatcaagtt agataaagtt
    50821 cctattaagt gttatgctaa ggaagaactt aggtccatta ctggcatggt attgcaagaa
    50881 acctggttga aagatgcgac tgttcatgag ttgattgctt acggcagtga agaggctagc
    50941 cgtgatgaag tagtggcagc agccaaagca gctcatgcac acttctttat tatgcaactt
    51001 cctaagactt atgatactta cttaagtgct tctgatgatg ctttgtccca agggcagctc
    51061 cagttattag ctattgccag aatgtttttg aaaaaaccaa aagtcttgat cctagatgaa
    51121 gccacctcct ctattgatat tagaacagaa gctgttattc aagaggtact aaaagaactc
    51181 atgagaggaa ggaccagctt tatcattgcc catcgtttat caacgattca atcagctgat
    51241 ttgattcttg ttatggatca aggtcgattg gttgagtggg gaacacatgc cagcttaatg
    51301 tcaaaaaacg gatgttatgc tagattacaa aagatagaat aaagttcgtc ttttaacaaa
    51361 gatgaacttt tttaatcttc ctaaagttag ttaattaaca aactttaaac tgttatataa
    51421 aaaaataaca gcgaaaaagc ggacaatctt ttttataagt gagaaaaaac agttgactaa
    51481 agaagaaata actcaaaaaa gtgagcaata tatttggaag cgttttttga ctgtggtata
    51541 atagagccct atataatatt gtgaaatgag gaacaaaata tatgagtaaa atcgttgttg
    51601 ttggtgcaaa ccatgctggt acggcctgta tcaagactat gttaacaaac tacggtgatg
    51661 ctaatgagat tgttgtattt gaccaaaact caaatatttc atttttaggc tgtggtatgg
    51721 cactttggat tggtgagcaa attgctggac cagaaggact tttctattca gataaagaag
    51781 aattagagtc tttaggggct aaagtttaca tggaatcacc tgttcaatca atcgactacg
    51841 atgccaaaac agtgacagcg cttgttgatg gtaaaaacca cgtggaaact tacgacaagt
    51901 tgatttttgc aactggctca caacctatct taccaccgat taaaggtgcc gaaatcaaag
    51961 aaggatcact tgaatttgaa gcaactcttg aaaatcttca atttgtgaag ttataccaaa
    52021 actcagctga tgtgattgca aagcttgaaa acaaagacat taaacgtgta gccgtagttg
    52081 gtgctggtta cattggtgtt gagttagctg aagctttcca acgcaaaggc aaagaagtgg
    52141 ttctgattga tgtcgtggac acttgcttgg caggttatta cgaccgtgat ttgactgact
    52201 taatggctaa aaacatggaa gaacatggta ttcaactagc ctttggtgaa acagttaaag
    52261 aagtagctgg taatggtaag gttgaaaaga tcattactga caaaaatgag tacgatgtgg
    52321 atatggttat cctcgccgtt ggtttccgtc caaacacaac tcttggaaat ggtaagattg
    52381 atcttttccg taatggtgct ttccttgtca ataaacgcca agaaacttct attccaggtg
    52441 tttatgctat cggtgactgt gcaactatct acgataatgc tactcgcgat acaaactaca
    52501 ttgctttagc ttcaaatgct gtccgtacag gaattgtagc agcacataac gcttgtggta
    52561 cagaccttga aggaatcggt gtccaaggct caaacggtat ttccatttac ggcttgcaca
    52621 tggtatcaac tggtttgact cttgaaaaag ctaaacgact tggttttgat gctgcagtga
    52681 ctgagtatac tgataaccaa aaacctgaat ttatcgaaca cggtaacttc ccagtaacca
    52741 ttaagattgt ttacgataaa gactcacgtc gtatcttggg tgctcaaatg gcagcccgtg
    52801 aagatatgtc aatgggaatt cacatgttct cacttgctat ccaagaagga gtgaccattg
    52861 aaaagttggc attaactgat attttcttct taccacattt caacaaacct tacaactaca
    52921 tcacaatggc agcacttggt gccaaagact agtatctgat aggaaaaagc cagagcagtt
    52981 cagcagcact ggcttttttg ctttttaatt gttgcaacct gaaaagttct aaacttatgt
    53041 ttatcctctt atagcacgtt ggaaaaggaa tatcaggcaa aacaaaaaga gaccgaagtc
    53101 tcttttgtga ttagttttta gcagcagaag caaattcttc cttagcgaaa gcttcatcga
    53161 tgatagcttt taattgattt gcagaggctt gcattttttg caattcagca tcgttaagtg
    53221 gaatgtttac tggacgaaca attccatacg ctccaacgat agctggttga ccaatatagc
    53281 aatcttcaac accttcgtat tggccttctt ggaaaacaga aagcggaaga acagcatttt
    53341 catcatcaag aatagctttt gtaatacgag ctagggcaac tgcaataccg tagaaagtag
    53401 cacctttttt attgatgatt gagtaagcag catcacgtac agaaatgaaa agatcaacta
    53461 ggccttgctc atcaatgtca cgattagctt ggagccagtc gtaaagacct acaccagcaa
    53521 cgttagcgtg tgaccaaaca gcaaattcag agtcaccgtg ttctcccatg atgtaagcgt
    53581 gaaccgaacg cgcatcaacc ccaattttag cagctagtgc ttgacggaag cgggctgaat
    53641 ctagtgatgt acctgatcca a
//
LOCUS       DAXMQE010000012        47860 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.012, whole genome shotgun sequence.
ACCESSION   DAXMQE010000012 DAXMQE010000000
VERSION     DAXMQE010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 47860)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47860)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47860
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.012"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            54..941
                     /gene="pstA"
                     /locus_tag="ACF4ZO_000776"
     CDS             54..941
                     /gene="pstA"
                     /locus_tag="ACF4ZO_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008088954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HFD5486338.1"
                     /translation="MNAKKVDKVATGTLYTIAGIIVAILASLILYILVRGLPHISWSF
                     LTGKSSSYEAGGGIGIQLYNSFFLLIVTLIISIPLSTGAGIYLAEYAKKGPVTNFIRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLLHVH
                     HTQREAGLALGLSRWETVFYVVIPEALPGMVTGIVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNPLSVTSPISIFRQSETLAVHIWKVNSEGTIPDATLVSAGSAAVLLIFILIF
                     NFSARFIGKKLHSKMTAAK"
     gene            957..1760
                     /gene="pstB"
                     /locus_tag="ACF4ZO_000777"
     CDS             957..1760
                     /gene="pstB"
                     /locus_tag="ACF4ZO_000777"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HFD5486339.1"
                     /translation="MTEYNWNERHIITFPEETLALATKDLHVYYGAKEAIKGIDMQFE
                     KHKITALIGPSGCGKSTYLRSLNRMNDTIDIARVTGEILYQGIDVNRKDMNVYEIRKH
                     LGMVFQRPNPFAKSIYKNITFAHERAGVKDKKVLDEIVETSLKQAALWDQVKDDLHKS
                     AFTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNYTIIIV
                     THNMQQAARASDYTAFFYLGNLIEYDKTRNIFQNAQCQSTNDYVSGHFG"
     gene            1773..2531
                     /gene="pstB"
                     /locus_tag="ACF4ZO_000778"
     CDS             1773..2531
                     /gene="pstB"
                     /locus_tag="ACF4ZO_000778"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HFD5486340.1"
                     /translation="MTEPILQIRDLSVYYNQKKTLKDVSLDLYPNEITALIGPSGSGK
                     STLLRSINRMNDLNPEVTITGSIVYNGHNIYSPRTDTVDLRKEIGMVFQQPNPFPMSI
                     YENVVYGLHLKGIRDKSILDHAVESSLKGASIWNEVKDRLHDSAVGLSGGQQQRVCIA
                     RVLATSPRIILLDEPTSALDPISAGKIEETLLLLKKDYTLAIVTRSMQQASRLSDRTG
                     FFLEGDLLECGPTKAMFMNPKRKETEDYISGKFG"
     gene            2599..3252
                     /gene="phoU"
                     /locus_tag="ACF4ZO_000779"
     CDS             2599..3252
                     /gene="phoU"
                     /locus_tag="ACF4ZO_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA];
                     GO_process: GO:0030643 - intracellular phosphate ion
                     homeostasis [Evidence IEA];
                     GO_process: GO:0045936 - negative regulation of phosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HFD5486341.1"
                     /translation="MLRTKFEEELDKLHNQFYSMGTEVLAQINKTVRAFVSHDRELAK
                     EVIEEDDTINNFETKLEKKSLEIIALQQPVSNDLRMVITVLKASSDIERMGDHAASIA
                     KATIRMKGEERIPVVEEQINLMGKAVKQMVEEALNAYINADDTKAYEIAASDEIIDQY
                     FRNIQTLAVEEIRKSPDAVFAGKEYFQVLMYLERIGDYARNICEWIVYLKTGKIIEL"
     gene            3457..5994
                     /locus_tag="ACF4ZO_000780"
     CDS             3457..5994
                     /locus_tag="ACF4ZO_000780"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008237 - metallopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HFD5486342.1"
                     /translation="MKTVEHLIETFVPENYNIFLDINRQTKTFTGNVAINGEALDNHV
                     AFHQKDLDIKSILLDNEAVIYQVDNDNEVVRVELPETGMMTLVIEFSGSITDNMTGIY
                     PSYYTKNGEKKEVISTQFESHFAREAFPCIDEPQAKATFDLSLTFDQEIGEIALSNMP
                     EVNIDRREETGLWTFDTTPRMSSYLLAFALGELHGKTVESKKGTTVGVYATTAHPLSS
                     LDFSLDIAVRVINFYEDYFGVHYPIPQSLNIALPDFSSGAMENWGLITYREIYLLVDE
                     NSTVQSRQQVALVIAHEIAHQWFGNLVTMKWWDDLWLNESFANMMEYVSIEAIEPSWK
                     IIEDFQTGGIPLALKRDATDGVQSVHVEVNHPDEINTLFDPAIVYAKGSRLMHMLRRF
                     IGDRDFAIGLHHYFEKYQYRNTVGRDLWNILSDTSGKDVAAFMDAWLEQPGYPVLTAR
                     LENDQLILSQKQFFIGKGEEKGRLWPIPLNTNWHGLPETLTEAEMVIPNFSQLAAENE
                     GALRFNIDNTAHYITDYQGSLLDALVTELAQLDNTSALQVIQERRLLADSGLISYAEL
                     VDLIAQLDDSKSYMVAEAVQQVVSGLKRFIDEGSLAEKSFNRLVTTIYQEDFNQHGFE
                     KKADESDEDEMVRQVALGRLWLAENQTIIDGLRTIFEAYQNNIASIPAAVRRLVLANQ
                     MKYFEIDSLVDIYFETYVATTDNNLRSDLTVAFSQTKQLTTIRRILVSLKDKDIIKPQ
                     DLSYWYNALLGQSFTQDIIWEWARENWDWIKSALGGDMSFDKFVIYPASNFKTPKHLA
                     EYKSFFEPKLDDMAISRNITMGINEVEARVALITKEKEAVIAALSHY"
     gene            6340..7014
                     /locus_tag="ACF4ZO_000781"
     CDS             6340..7014
                     /locus_tag="ACF4ZO_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFD5486343.1"
                     /translation="MIKILLVEDDLSLSNSIFDFLDDFADVMQVFDGDEGLYEAESGI
                     YDLILLDLMLPEKNGFQVLKELREKDIKIPVLIMTAKEGLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRTGKFADKNISFGNLVVDLARKEVKVEGKVVELLGKEFDLLVY
                     LLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYISKIRKKLKGTRFVNRLQTLRSVGY
                     ILKNNE"
     gene            7007..8317
                     /locus_tag="ACF4ZO_000782"
     CDS             7007..8317
                     /locus_tag="ACF4ZO_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HFD5486344.1"
                     /translation="MNKLKKEILSDNYNHFFHFFAVFTGIFVIMTIIILQIMRFGVYS
                     SVDSSLVSVSNNASSYANRTMARISSFYFDTENNIIKALPDSDSSKLLGTPAANTDII
                     LFSANGTILNAFDAFSNYQNFHLDKHRLGSIETTSLMNFYGQEEKYHTITVRVHIKNY
                     PAVAYMMAVVNVEQLDRANERYERIIIIVMSVFWLISILASIYLAKWSRKPILESYEK
                     QKMFVENASHELRTPLAVLQNRLESLFRKPNETILENSEHLASSLDEVRNMRILTTNL
                     LNLARRDDGINPQWTHLDTDFFNAIFENYELVAKEYGKIFYFQNQVNRSLRMDKALLK
                     QLITILFDNAIKYTDKNGIIEIIVKTTDKNLLISVIDNGPGITDEEKKKIFDRFYRVD
                     KARTRQTGGFGLGLALAQQIVMSLKGNITVKDNDPKGSIFEVKL"
     gene            complement(8442..8690)
                     /gene="rpsT"
                     /locus_tag="ACF4ZO_000783"
     CDS             complement(8442..8690)
                     /gene="rpsT"
                     /locus_tag="ACF4ZO_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HFD5486345.1"
                     /translation="MEVKTLANIKSAIKRAELNVKANEKNSAQKSAMRTAIKAFEANP
                     SEELFRAASSSIDKAESKGLIHKNKASRDKARLAAKLG"
     gene            complement(8744..9664)
                     /gene="coaA"
                     /locus_tag="ACF4ZO_000784"
     CDS             complement(8744..9664)
                     /gene="coaA"
                     /locus_tag="ACF4ZO_000784"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004594 - pantothenate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HFD5486346.1"
                     /translation="MSNEFINFEKISRESWKTLHQKAKALLTQEELKSITSLNDNISI
                     NDVIDIYLPLINLIQVYKIAQENLSFSKSLFLKKDIQLRPFIIGISGSVAVGKSTTSR
                     LLQLLLSRTHPNSQVELVTTDGFLYPNQFLIEQGLLNRKGFPESYNMELLLDFLDSIK
                     NGQTAFAPVYSHDIYDIIPNQKQSFNNPDFLIVEGINVFQNQQNNRLYMSDYFDFSIY
                     IDADSSHIETWYIERFLSILKLAKRDPHNYYAQYAQLPRSEAIAFARNVWKTVNLENL
                     EKFIEPTRNRAELILHKSADHKIDEIYLKK"
     gene            9932..10525
                     /locus_tag="ACF4ZO_000785"
     CDS             9932..10525
                     /locus_tag="ACF4ZO_000785"
                     /EC_number="2.1.1.172"
                     /EC_number="2.1.1.174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0052916 - 23S rRNA
                     (guanine(1835)-N(2))-methyltransferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFD5486347.1"
                     /translation="MTKMYYDENPDSLHDIHEVKVELLNHPFTFLTDSGVFSKKMVDF
                     GSQVLLETLNFKENERVLDLGCGYGPLGISLAKVQRVDATLVDINNRALDLARKNATN
                     NQVAVTIFQSNIYENISGHFEHIISNPPIRAGKRVVHSIIEKSIDFLVVNGDLTIVIQ
                     KKQGAPSAKAKMATIFGNVEILRKDKGYYVLRSIKQA"
     gene            11179..11568
                     /locus_tag="ACF4ZO_000786"
     CDS             11179..11568
                     /locus_tag="ACF4ZO_000786"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004126 - cytidine deaminase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0009972 - cytidine deamination [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HFD5486348.1"
                     /translation="MGTTDLVSCAVQASEYAYVPYSHFPVGAALKTKDGTIYTGCNIE
                     NVSFGLTNCGERTAIFKAISDGHKELVEIAIYGETMQPVSPCGACRQVMAEFFAPSSL
                     VTLIAKNGQTVEMTVGDLLPYSFTDLI"
     gene            11662..12714
                     /locus_tag="ACF4ZO_000787"
     CDS             11662..12714
                     /locus_tag="ACF4ZO_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HFD5486349.1"
                     /translation="MNKKFISLGLASVAVLSLAACGNRGASKGGAAGKTDLKVAMVTD
                     TGGVDDKSFNQSAWEGLQSWGKEMGLQKGTGFDYFQSTSESEYATNLDTAVSGGYQLI
                     YGIGFALKDAIAKAAGDNEGVKFVIIDDIIEGKDNVASVTFADHEAAYLAGIAAAKTT
                     KTKTVGFVGGMEGTVITRFEKGFEAGVKSVDDTIQVKVDYAGSFGDAAKGKTIAAAQY
                     AAGADVIYQAAGGTGAGVFNEAKAINEKRSEADKVWVIGVDRDQKDEGKYTSKDGKEA
                     NFVLASSIKEVGKAVQLINKQVADKKFPGGKTTVYGLKDGGVEIATTNVSKEAVKAIK
                     EAKAKIKSGDIKVPEK"
     gene            12853..14385
                     /locus_tag="ACF4ZO_000788"
     CDS             12853..14385
                     /locus_tag="ACF4ZO_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD5486350.1"
                     /translation="MTQHVIEMREITKKFGDFVANDHINLNVRKGEIHALLGENGAGK
                     STLMNMLAGLLEPTSGEIVINDKPVQIDSPSKSAKLGIGMVHQHFMLVEAFTVAENII
                     LGNEVVKNGCLDLNQASKDIKVLSEKYGLAINPSAKVSDISVGAQQRVEILKTLYRGA
                     DILIFDEPTAVLTPAEIKELMTIMKNLVKEGKSIILITHKLDEIRAVADRVTVIRRGK
                     SIETVDVAGATSQDLAEMMVGRSVSFTTSKKAAEPKDVVLSIKNLEVDENRGIPAVKG
                     LSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVKSGSIMIKNNEVTHLSSRKITELS
                     VGHVPEDRHRDGLILDLSLAENTALQTYYKQPLSQNGILNYTKINDYARQLMKEFDVR
                     GANELVPARGFSGGNQQKAIIAREVDRDPDLLIVSQPTRGLDVGAIEYIHKRLIKERD
                     KGKAVLVVSFELDEILNLSDRIAVIHDGKIQGIVLPENTNKQELGILMAGGSIHKEEG
                     HV"
     gene            14378..15442
                     /locus_tag="ACF4ZO_000789"
     CDS             14378..15442
                     /locus_tag="ACF4ZO_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD5486351.1"
                     /translation="MSKNAQKIAVPLISVLLGFLLGAIIMVIFGYDPIWGYEGLFQIA
                     FGSVKNIGEIFRSMGPLILIALGFTVASRAGFFNVGLSGQALAGWISAGWFALLNPDM
                     PRPLLILMTALIGMIAGGIAGAIPGILRAYLGTSEVIVTIMMNYIILYVGNAIVQRGY
                     PESVKQSIDSTIQVSDNASYQTHWLSALTNNSRINIGIFFAIIAIALIWFLLNKTTLG
                     FEIRSVGLNPHASEYAGMSSKRTIILSMIISGALAGLGGVVEGLGTFENVFVQGSSLA
                     VGFDGMAVSLLAANSPLGIFFSSFLFGVLNIGAPGMNIAGIPPELVKVVTASIIFFVG
                     SHYLIERYIIRPKKLVKGGK"
     gene            15444..16400
                     /locus_tag="ACF4ZO_000790"
     CDS             15444..16400
                     /locus_tag="ACF4ZO_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002268043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD5486352.1"
                     /translation="MSLVTIFALLVSSMLIYATPLIFTSIGGTFSERSGVVNVGLEGI
                     MVMGAFSGIVFNLEFAETFGKATPWIAVLVGGIVGLIFSLIHAVATINFRADHIVSGT
                     VLNLLAPSFAVFLVKAMYGKGQTDNIQQSFGKFDFPGLSQIPVIGDIFFKNTSLIGYF
                     AIAFSFFAWFLLYKTRFGLRLRSVGEHPQAADTLGINVYLMKYYGVMISGFLGGIGGA
                     VYAQSISVNFAVTTILGPGFIALAAMIFGKWNPVGAMLSSLFFGLSQSLAVIGAQLPL
                     LEKIPTVYLQIAPYMVTIIILAAFFGQAVAPKADGINYIKSK"
     gene            complement(16618..18336)
                     /locus_tag="ACF4ZO_000791"
     CDS             complement(16618..18336)
                     /locus_tag="ACF4ZO_000791"
                     /EC_number="5.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016868 - intramolecular
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HFD5486353.1"
                     /translation="MTYTENFQKWLDFEQLPDYLRQELLSMDEKTKEDAFYTNLEFGT
                     AGMRGYIGAGTNRINIYVVRQATEGLAKLIETKGEEAKKRGVAIAYDSRHFSPEFAFE
                     SAQVLAQHGIKSYVFEALRPTPELSFAVRHLNAYAGIMVTASHNPAPFNGYKVYGQDG
                     GQLPPADADALTDFIRAIENPFAVELADLDESKSSGLIQVIGEDVDMEYLREVKDVNI
                     NQVLINNFGKDMKIVYTPLHGTGEMLTRRALAQAGFESVVVVESQAKADPDFSTVKSP
                     NPESQAAFALAEELGREVDADVLVATDPDADRLGVEIRQPDGSYKNLSGNQIGAIIAK
                     YILEAHKTAGTLPENAALAKSIVSTELVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMFGFEESFGYLIKPFVRDKDAIQAVLLVAEIAAYYRSRGLTLADGIDEIYKE
                     YGYFAEKTISVTLSGVDGAAEIKKIMDKFRENGPKQFDNTDIVLLEDFQKQTATKNDG
                     TISNLTTPPSNVLKYTLADDSWIAVRPSGTEPKIKFYIATIGDTLDIAQEKIANIETE
                     INTFVG"
     gene            complement(18512..19081)
                     /locus_tag="ACF4ZO_000792"
     CDS             complement(18512..19081)
                     /locus_tag="ACF4ZO_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HFD5486354.1"
                     /translation="MNHRKSADISRIAIFFAIMLVIHFVSSLVFNIWPIPIKPTLVHI
                     PVIIASVLYGPRIGAILGGLMGIISVITNTIILLPTNYLFSPFVDHGTFASLIIAIIP
                     RILIGITPYYCYKLIPNQFGLIVSGIIGSLTNTIFVLSGIFIFFATVFDGNIKALLTA
                     IISSNAIVEMIISAIITFVLIPTLSRLKR"
     gene            complement(19139..19684)
                     /gene="coaC"
                     /locus_tag="ACF4ZO_000793"
     CDS             complement(19139..19684)
                     /gene="coaC"
                     /locus_tag="ACF4ZO_000793"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004633 - phosphopantothenoylcysteine
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HFD5486355.1"
                     /translation="MTKHITLAVSGSISAYKAADLTSQLTKMGYDVHIIMTQAATQFI
                     TPLTLQVLSKNAIHLDVMDEHDPKVINHIELAKRTDLFIVAPASANTIAHLAYGFADN
                     IVTSVALALPATTPKLIAPAMNTKMYQNPITQENIKRLSTIGFTEIPPKSSLLACGDK
                     GLGALADIDVILATIDTIWKL"
     gene            complement(19677..20363)
                     /gene="coaB"
                     /locus_tag="ACF4ZO_000794"
     CDS             complement(19677..20363)
                     /gene="coaB"
                     /locus_tag="ACF4ZO_000794"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004632 - phosphopantothenate--cysteine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HFD5486356.1"
                     /translation="MKLIITSGGTTEPIDAVRGITNHSTGQLGKLITERFLQYHHDVT
                     LVTTKTATKPLPNERLRIIEVETVNDLMAALKDQVPHHDILIHSMAVSDYTPVYMTDL
                     EQVSQADNLNCFLCEHNSEPKISSASDYQVLFLKKTPKVISYVKQWNPNIKLVGFKLL
                     VNVPQEELIKVARASLVKNHADYILANDLVDIQTGMHKALLISNNEVASADTKEAIAD
                     LLYERMTKHD"
     gene            20565..21401
                     /locus_tag="ACF4ZO_000795"
     CDS             20565..21401
                     /locus_tag="ACF4ZO_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin/lipoate A/B protein ligase family
                     protein"
                     /protein_id="HFD5486357.1"
                     /translation="MITIRDLASLPIFVYGDGNKKVPGALSPFVWTEVFLKTINQEPN
                     QLILHIWPMTRTVILGMLDRQLPYFELAKKEIGNNGYVPVTRNIGGLAVVADDGILNF
                     SLVIPDHFSESISISNAYLIMVDVIRESFSDYYQRIEYHEIKNSYCPGNFDLSIAGRK
                     FAGIAQRRIKKGIVVSIYLSVCGDQAARGQLIKAFYEAGTQGEVTKVNYPQIDPECMA
                     TLSELLETPFTVAEVLERLRLTLRQLGFSLTEKSPDQALLTNFDAVYERMQLEVVRKE
                     GK"
     gene            21398..22597
                     /locus_tag="ACF4ZO_000796"
     CDS             21398..22597
                     /locus_tag="ACF4ZO_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HFD5486358.1"
                     /translation="MKERFSPLFELLTLPNGSQLDNRFVLSPMVTNSSTKDGYVTQDD
                     ISYALRRAASAPLQITGAAYVDPYGQLFEYGFSVTKDADISGLKELAQAMKAKGAKAV
                     LQLTHAGRFASHALTKYGFVYGPSYMQLRSPQPHEVKPLTGQQIEELVAAYAQATRRA
                     IQAGFDGVEVSSAQRLLIQTFFSTFSNKRTDSYGCQTLFNRSKLTLAVLQAVQQVIKQ
                     EAPDGFIFGFRATPEETRGNDIGYSIDEFLQLMDWVLNVAKLDYLAIASWGRHVFRNT
                     VRSPGPYYGRRVNQVVRDYLRNKLPVMATGGMNTPDKAIEALAHADFIGVSTPFVVDP
                     EFAHKIKEGCEESIHLRIRPADLKSLAIPQASFKDIVPLMDYGESLPKESRTLFRSLT
                     HNYKEIK"
     gene            22594..23592
                     /locus_tag="ACF4ZO_000797"
     CDS             22594..23592
                     /locus_tag="ACF4ZO_000797"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HFD5486359.1"
                     /translation="MKVSILDYGVIDKEKTSQEALLETRCLAQVADKLGFHRFWVAEH
                     HNIYAFAISSPELLMMHLADHTKQIRIGSGGIMPLHYSSFKIAEWIMTLEALHPNRID
                     LGIGNSLGTTLVQRALSSIHCKDSYSQVVTELYQYLNPDHLSPLPIFVNPRGNTYPQI
                     WTLSNSLETAELAGQLGLGYTFGIFPYIPKDPITEAKRVSAHYRKAFRPSKLLKIPKL
                     ILAVFIVLSDTDEEAEALAKPLDIWMLGQQDFNEFKTYPDVEEARNYHLTEKQREAIA
                     ANRSRMVIGPPHTVKKQLDRLIEACQADELLAIPLVPEFANRQRTLELLADLYVTI"
     gene            23634..23966
                     /locus_tag="ACF4ZO_000798"
     CDS             23634..23966
                     /locus_tag="ACF4ZO_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HFD5486360.1"
                     /translation="MKKIANYLLIEKTDDRYTISMTPELQDDIGTIGYAEFTDNDHLA
                     VDDIILNLEASKTVMSVLSPLAGAVVERNEAATLTPTLLNSEKAEENWIVVLTDVDQA
                     AFDALEDA"
     gene            23959..24771
                     /locus_tag="ACF4ZO_000799"
     CDS             23959..24771
                     /locus_tag="ACF4ZO_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-ADP-ribose hydrolase"
                     /protein_id="HFD5486361.1"
                     /translation="MPSSFDLLGEMIGLLQTEQLTSSLACPLPNALTKRQDLWRALIN
                     QRPALPLSKDYLNLEDAYLDDWRASFVPVSVKDCQKTNYTSLFLYHGDIRYLAVDAIV
                     NAANSELLGCFIPNHGCIDNAIHTFAGSRLRLACQAIMTEQGRKEAIGQAKLTSAYHL
                     PASYIIHTVGPRITKGRHVSPIRADLLARCYRSSLDLAVKAGLTSLAFCSISTGEFGF
                     PKKEAAQIAIKTVLKWQAEHPESKTLTVIFNTFTSEDKALYDTYLQKENNCE"
     gene            24764..25645
                     /locus_tag="ACF4ZO_000800"
     CDS             24764..25645
                     /locus_tag="ACF4ZO_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent deacetylase"
                     /protein_id="HFD5486362.1"
                     /translation="MSNWTTYPQKNLTQAEQLAQLIKEADALVVGIGAGMSAADGFTY
                     IGPRFETAFPDFIAKYQFLDMLQASLFDFEDWQEYWAFQSRFVALNYLDQPVGQSYLD
                     LKEILETKDYHIITTNADNAFWVAGYDPHNIFHIQGEYGLWQCSQHCHQQTYKDDTVI
                     RQMIAEQKNMKVPGQLIPHCPECEAPFEINKRNEEKGMVEDADFHAQKARYEAFLSEH
                     KEGKVLYLEIGVGHTTPQFIKHPFWKRVSENPNALFVTLNHKHYRIPLSIRRQSLELT
                     EHIAQLISATKTIYQKS"
     gene            25692..26711
                     /locus_tag="ACF4ZO_000801"
     CDS             25692..26711
                     /locus_tag="ACF4ZO_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HFD5486363.1"
                     /translation="MYLIEPIRNGKRITDGAVALAMQVYVQENLFLDDDILFPYYCDP
                     KVEIGKFQNAVVETNQEYLKEHHIPVVRRDTGGGAVYVDSGAVNICYLINDNGVFGDF
                     KRTYQPAIEALHHLGATGVEMSGRNDLVIDGKKVSGAAMTIANGRVYGGYSLLLDVDF
                     EAMEKALKPNRKKIESKGIRSVRSRVGNIREHLAPQYQGITIEEFKDLMICQLLQIET
                     ISQAKRYDLTEKDWQQIDALTERKYHNWEWNYGNAPQYRYHRDGRFTGGTVDIHLDIK
                     KGYIAACRIYGDFFGKADIAELEGHLIGTRMEKEDVLATLNAIDLAPYLGAITAEELG
                     DLIFS"
     gene            26840..28510
                     /locus_tag="ACF4ZO_000802"
     CDS             26840..28510
                     /locus_tag="ACF4ZO_000802"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004329 - formate-tetrahydrofolate ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HFD5486364.1"
                     /translation="MKSDIEIAQSVALQPITDIVKKVGIDGDDIELYGKYKAKLSFEK
                     MKAVEANEPGKLILVTAINPTPAGEGKSTMSIGLADALNQMGKKTMLALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLQQGNDLGIDPRR
                     IIWKRVLDLNDRALRQVIVGLGSPVNGVPREDGFDITVASEIMAILCLATDLKDLKKR
                     LADIVVAYTYDRKPVYVRDLKVEGALTLILKDAIKPNLVQTIYGTPALIHGGPFANIA
                     HGCNSVLATSTALRLADYTVTEAGFGADLGAEKFLNIKVPNLPKAPDAIVIVATLRAL
                     KMHGGVAKSDLAAENCEAVRLGFANLKRHVENMRQFKVPVVVAINEFVADTEAEIATL
                     KALCEEIKVPVELASVWANGAEGGLALAKTVVRVIDQEAADYKRLYSDEDTLEEKVIN
                     IVTQIYGGKAVQFGPKAKTQLKQFAEFGWDKLPVCMAKTQYSFSDNPSLLGAPTDFDI
                     TIREFVPKTGAGFIVGLTGDVMTMPGLPKVPAAMAMDVAENGTALGLF"
     gene            28595..30172
                     /gene="cls"
                     /locus_tag="ACF4ZO_000803"
     CDS             28595..30172
                     /gene="cls"
                     /locus_tag="ACF4ZO_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008808 - cardiolipin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HFD5486365.1"
                     /translation="MIIKKKAKVKYLLHKGKHGFLRGIFSRTTIIVLLIILQLVFLFQ
                     SYAWMEQYRVWITILESVFAITIVLYLVNSDMDAISRMTWLILIMIAPLLGSLFLIYT
                     KLDWGYRGLKQRINHLVDLSAPYLSDDDAILEVLKDSTSTTYHLVQYLERSRGNFPIY
                     NNTRVTYFPTGETFFDSLKEQLFLAKKYIFLEFFIIAEGQMWGEILSILEKKVSEGVE
                     VRVLFDGMNELSTLSSDYAKRLEQIGIKAKSFLPISPFISTYYNYRDHRKIVVIDGEV
                     SFTGGINLADEYINEVERFGHWKDAGLMLEGEATDSFLILFLQMWSITEKELIIDPYL
                     SDHSLKLPSDGYVIPYGDSPLDTDKIGKNVYIDILNHAKEYVYIMTPYLILDSEMEHA
                     LRFASERGVDIRIIMPGVPDKGVPYALAKTYYKALMTSGVKIYEYQPGFVHSKVFISD
                     NTKAVVGTINLDYRSLYHHFECATYLYRVSVIADIVNDFNEAQKQSLLMTSDHLTQRP
                     WYQKLIGLLVRTIAPLL"
     gene            30512..30850
                     /locus_tag="ACF4ZO_000804"
     CDS             30512..30850
                     /locus_tag="ACF4ZO_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001165748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP cone domain-containing protein"
                     /protein_id="HFD5486366.1"
                     /translation="MQIIKRDGHVADFDPDKIYQAIIKAARTVYVIDDTWRQNLTHVT
                     KKVVIDLEEAHVERPTINMVQSLVENRLMDAGYITIAEHYISYRLQRDLERNGYGDKI
                     VVHLRFEQIK"
     gene            complement(31258..32526)
                     /locus_tag="ACF4ZO_000805"
     CDS             complement(31258..32526)
                     /locus_tag="ACF4ZO_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HFD5486367.1"
                     /translation="MTTKYQTIISNIEQDIQKQRLKKGDKLPSIRVLSKVYHCSKDTV
                     QRALLELKYRHLIYAVPKSGYYVLGNVSIPDNVLNLSLEDYNNMAYEDFRLCLNEALS
                     AKGKYLFHYYHKTEGLEELREALLLYLAENSVYSNKDQLLITSGTQQALYILSQMPFP
                     NAGKTILLEKPTYHRMEAIVAQLGLPYQTISRHFNGLDLELLESLFQTGDIKFFYTIS
                     RFSHPLGLSYNTKEKEAIVRLAQRYQVYILEDDYLGDFVKLKEPPIHYYDTHHRIIYL
                     KSFSMSVFPALRIGALVLPSGLKPHFLTQKSLIDLDTNLLMQKALALYLENGMFQKNL
                     RFIKRYLKQRERQLALFLKQNCPDIHYQLTPTHLVIDYTTSDSYRNFTLDKSDRIIIT
                     GKKRYLSIAINQQIQSKLNSLIKNTCGKSN"
     gene            32616..33482
                     /locus_tag="ACF4ZO_000806"
     CDS             32616..33482
                     /locus_tag="ACF4ZO_000806"
                     /EC_number="2.7.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008478 - pyridoxal kinase activity
                     [Evidence IEA];
                     GO_process: GO:0009443 - pyridoxal 5'-phosphate salvage
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine kinase"
                     /protein_id="HFD5486368.1"
                     /translation="MKRIIVANDLVGVGKVALSASIPLMASCLLEQVLLPTCLLSSHT
                     GGGQNPVKHTTSSILDVFLTDWDNKRIKFDGIFIGYFTTTRDGQKLLEWLSRKQLPLI
                     LDPIMADNGKLYQGFSQKHIEIMIKLTQKAELVLPNISEACLLTQTAYLAKNYDEEDI
                     RQVARKLAKLGPKQVVISGISFEEGSIGFAYYQSDSDQLTFHFGKQFPYHFYGTGDIA
                     SAIITAGFYYQLPLTQILDLVVSFLEKVLQNTLTLKRDLILGVAYESHLNYLTKSFKK
                     LLEEKNVISKIS"
     gene            33460..34017
                     /locus_tag="ACF4ZO_000807"
     CDS             33460..34017
                     /locus_tag="ACF4ZO_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HFD5486369.1"
                     /translation="MSSQKLANYIELSMYAALIFISVQVLRVPVGMQFIHLGNALVVI
                     AVLIYGSKKGALVASLGLGIFDVLNGYASVVWITILESLAICLILHLVYERAMQSSKK
                     PKAIITITVIAALSKLTINLIKYLLLAYIGTQLPLSVSFWVALGKIGGSFGTSFVTLV
                     AVPLLYPVIKNLKEKVTIGQAKRGF"
     gene            34151..35695
                     /locus_tag="ACF4ZO_000808"
     CDS             34151..35695
                     /locus_tag="ACF4ZO_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HFD5486370.1"
                     /translation="MSILEVKQLSHGFGDRAIFENVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGHLQPDEGKVEWSKYVTAGYLDQHTVLESGQTVRDVLRTAFDELFKTENRIN
                     EIYASMADDKADIAVLMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMESDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNHLDAKHIEWLKRYLQHYENAFVLISHDI
                     SFLNDVINIVYHVENQSLVRYTGDYYQFQAVYEMKQSQLEAAYERQQKEIANLQDFVN
                     RNKARVATRNMAMSRQKKLDKMDIIELQAEKPKPNFEFKQARTPSRFIFQTKNLVIGY
                     DYPLTKEPLNITFERNQKIAIVGANGIGKSTLLKSLLGVIEPLEGHIVTGDFLEVGYF
                     EQEVTGVNRQTPLEVVWDAFPALNQAEVRAALARCGLTSKHIESQIQVLSGGEQAKVR
                     FCLLMNRENNVLILDEPTNHLDIDAKNELKRALKAYKGSILMVCHEPDFYNGWVTDTW
                     DFSKLT"
     gene            36060..37283
                     /locus_tag="ACF4ZO_000809"
     CDS             36060..37283
                     /locus_tag="ACF4ZO_000809"
                     /EC_number="2.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016755 - aminoacyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyltransferase"
                     /protein_id="HFD5486371.1"
                     /translation="MTNLTFYAKIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQN
                     ERIGIYKEEKQVASLSLLIKLLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKT
                     KKALFIKYDPAILLKQYALGQEEEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRF
                     QANIYTQENLEMQFPKHTRRLIKDAKQRGVETYRASQSELHKFSKIVSLTEKRKNISL
                     RNEAYFQKLMTTYGDKAYLHLAKVNIPQKLDQYRQQLILINQDITRTQAHQKKRLKKL
                     EDQKASLERYITEFEGFTDQYPEEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYL
                     LYPKVFQDAYQDGIIWANMGGVEGSLDDGLTKFKANFAPTIEEFIGEFNLPVSPLYHI
                     ANTMYKIRKQLKNKH"
     gene            complement(37325..38887)
                     /gene="guaA"
                     /locus_tag="ACF4ZO_000810"
     CDS             complement(37325..38887)
                     /gene="guaA"
                     /locus_tag="ACF4ZO_000810"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003922 - GMP synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016462 - pyrophosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0006177 - GMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HFD5486372.1"
                     /translation="MTEISILNDVQKIIVLDYGSQYNQLIARRIREFGVFSELKSHKI
                     TAQELREINPIGIVLSGGPNSVYADNAFGIDPEIFELGIPILGICYGMQLITHKLGGK
                     VVPAGQAGNREYGQSTLHLRETSKLFSGTPQEQLVLMSHGDAVTEIPEGFHLVGDSND
                     CPYAAIENTEKNLYGIQFHPEVRHSVYGNDILKNFAISICGARGDWSMDNFIDMEIAK
                     IRETVGDRKVLLGLSGGVDSSVVGVLLQKAIGDQLTCIFVDHGLLRKDEGDQVMGMLG
                     GKFGLNIIRVDASKRFLDLLADVEDPEKKRKIIGNEFVYVFDDEASKLKGVDFLAQGT
                     LYTDIIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRALGIALGMPEEI
                     VWRQPFPGPGLAIRVMGPITEEKLETVRESDAILREEIAKAGLDRDVWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAQLPWDVLKKISTRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            39054..40487
                     /locus_tag="ACF4ZO_000811"
     CDS             39054..40487
                     /locus_tag="ACF4ZO_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486373.1"
                     /translation="MLRKKRILGLFRPVELIFLGLLLSLVVSYLAWTNSFATLHNILA
                     TVGIVERSKDQQPRYHIGQAIQVQKSGPYHQWIGTINKQVEDIAENYRVSYHYEVVFP
                     IGKVTVSLPEHNLKKPDKPRFKKGDIVKLSSLTKKPHIKVYQGQLATIKQVKKRYDYS
                     LGGYQYDINLKDNLRLDGISEQDFVKPYYIRFNKGNSPEQNNRLLRKAFAYAKQHPNS
                     VISFPKGQFHIGSLPSQKDYFELPSDTAIIGHQTEFIIHGKMLWFGFPTGPKAEQGVR
                     NLVLTGVHFKANDLKKGDHFMIMADHGTDWHIYDNKFTMVHKRNSHIFDLGSLQNSLF
                     EKNQFIGYAPELVQDQQLLSKAQGHDFFSEVIQFDAAVHHFAWDGGLLSNIAPNYEAF
                     NQTRHLCHNITVSQNQFLPYIDPTGCLRAYSGSIGQHSSKVGVIRVLNNVFTSSIVTK
                     AKLTSWFMEPIHFPPNSPVIVAGNIIN"
     gene            40570..41268
                     /locus_tag="ACF4ZO_000812"
     CDS             40570..41268
                     /locus_tag="ACF4ZO_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFD5486374.1"
                     /translation="MLPAYIKIHDAIKKDIDLGIWPIGSRLPSERHLAEHFTVSRMTL
                     RQAITLLVEEGILERRIGSGTYVASHRVQEKMRGTTSFTEIIRSQGRQPSSKLLSYQK
                     QLASDTEVKELNLDKTDLVIRMERIRYADSVPLVYEIASIPEKFIKTVKRADITEHFF
                     HSLIANGYEIGKSKQTIYAKLASERVASYLEVAKGHAILALTQVSYFTDGKPFEYVRS
                     QYIGDRFEFYLENN"
     gene            41366..41698
                     /locus_tag="ACF4ZO_000813"
     CDS             41366..41698
                     /locus_tag="ACF4ZO_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HFD5486375.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIADE
                     FGVSRQAVYDNIKRTEKILETYEMKLHMYSDYVVRSEIFDDMIAHYPHDEYLQEKISI
                     LTSIDNRE"
     gene            41713..43275
                     /gene="ffh"
                     /locus_tag="ACF4ZO_000814"
     CDS             41713..43275
                     /gene="ffh"
                     /locus_tag="ACF4ZO_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0048501 - signal recognition particle,
                     plasma membrane targeting [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005048 - signal sequence binding
                     [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HFD5486376.1"
                     /translation="MAFESLTQRLQDVFKHIRGKKKLSESDVQEVTKEIRLALLEADV
                     ALPVVKTFIKRVRERAIGHEIIDTLDPTKQILKIVNEELTSILGSETAEIDKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLIKEEDARPLMIAADIYRPAAIDQLKTLGQQINVPV
                     FDMGTDHSAVDIVRKGLEQARENHNDYVLIDTAGRLQIDEKLMEELRDVKALAQPNEI
                     LLVVDSMIGQEAANVAYEFNHQLSITGVVLTKIDGDTRGGAALSVREITGKPIKFTGT
                     GERITDIETFHPDRMSSRILGMGDLLTLIEKASQEYDEKKSLELAEKMRENTFDFNDF
                     IEQLDQVQNMGPMEDLLKMIPGMAGNPALANIKVDENQIARKRAIVSSMTPAERENPD
                     LLNPSRRRRIAAGSGNSFVEVNKFIKDFNQAKSMMQGVMSGDMSKMMKDMGINPNNLP
                     KNMPAGMPDMSSLEGMMGQGGMPDLSSLGGDMDMSQLFGGGFKGKIGQFAMKQAMKRQ
                     ANKLKKAKKKRK"
     gene            complement(43410..44108)
                     /locus_tag="ACF4ZO_000815"
     CDS             complement(43410..44108)
                     /locus_tag="ACF4ZO_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HFD5486377.1"
                     /translation="MFSGHQLKTARLSKGITQSELGGLLHVNKMTISNWEKGKNIPNE
                     KHLNALLHLFNVTSDYFDPNYKLLTPYNQLTISNKEKVIGYSERLLNHQIDKKSKDLI
                     DKPSQLYAYRVYESLSAGTGYSYFGDGNFDVVFYDEQLEYDFASWVFGDSMEPTYLNG
                     EVVLIKQNSFDYDGAIYAVEWDGQTYIKKVFREDEGLRLVSLNKKYSDKFAPYSEEPR
                     IIGKIIANFRPLEI"
     gene            44577..45647
                     /gene="xerS"
                     /locus_tag="ACF4ZO_000816"
     CDS             44577..45647
                     /gene="xerS"
                     /locus_tag="ACF4ZO_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012658412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HFD5486378.1"
                     /translation="MRRELLLEKIETYKAIMPWYVLDYYQSKLAVPYSFTTLYEYLKE
                     YKRFFDWLMDADLTQAPKIADIDLSTLEHLTKKDLEAFVLYLRERPSLNTYSTKEGLS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLASRAENIKQK
                     LFLGDETLAFLDYVDKEYEQKLSNRAKSSFRKNKERDLAIISLLLASGVRLSEAVNLD
                     LKDVNLNMMIIEVIRKGGKRDSVNVAGFAKGYLESYLAVRQRRYKAEKQDLAFFLTEY
                     RGVPNRMDASSIEKMVGKYSEDFKIRVTPHKLRHTLATRLYDATKSQVLVSHQLGHSS
                     TQVTDLYTHIVNDEQKNALDNL"
     gene            46346..46828
                     /locus_tag="ACF4ZO_000817"
     CDS             46346..46828
                     /locus_tag="ACF4ZO_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PASTA domain-containing protein"
                     /protein_id="HFD5486379.1"
                     /translation="MPKRIRKALGVVGKLMSIVPDTTEIIGKTIDNSRPIIEKRMEQK
                     HEKEMQLRTIDDVINLPVDQAQAHLEQLGFVVATIPAKPHKKWLHSNLNEVVAMSPKS
                     GKYKIGSLIKLYYITVDVVEKSQDLLDQENLRTVERNQKIADTFESVKHIRFPFKKWR
                     "
     gene            46917..>47860
                     /gene="citC"
                     /locus_tag="ACF4ZO_000818"
     CDS             46917..>47860
                     /gene="citC"
                     /locus_tag="ACF4ZO_000818"
                     /EC_number="6.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008771 - [citrate (pro-3S)-lyase] ligase
                     activity [Evidence IEA];
                     GO_process: GO:0006101 - citrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="[citrate (pro-3S)-lyase] ligase"
                     /protein_id="HFD5486380.1"
                     /translation="MPYYTISKVFPSDKTTMTSVKNLLHQEGIRLDAHLDYTCAIMNA
                     QNDVIATGSYFGNSLRCLCVSSAYQGEGLLNRIVSHLIDEEYALGNYHLFVYTKTSSA
                     AFFKDLGFTEIVHIDNHISFLENKKTGFQDYLMTLNKPEQTPGKVAAIVINANPFTLG
                     HQFLVEKAARENDWVHLFMVSEDRSLIPFSVRKRLIQEGLAHLDNVIYHETGPYLISQ
                     ATFPAYFQKEDNDVIKSQALLDTAIFLKIAQTLQITKRYVGEEPTSRVTAIYNEIMAE
                     QLQQAGILLDILPRKAINQQQDPISASTARQALKDNDW"
BASE COUNT        15267 a         7899 c         9466 g        15228 t
ORIGIN      
        1 tctggccttc aattcccttg tcaaattaat cacgaaagaa agaaagagaa attatgaacg
       61 ctaaaaaagt cgataaagta gcaactggta ctctttatac cattgctgga attattgtag
      121 ctattttagc ttccttaatt ctatatatcc ttgtccgtgg cttgccacac atcagctggt
      181 cctttttaac aggaaaatcg tcttcgtacg aagctggtgg gggaattggt atccagttgt
      241 ataattcctt cttcctattg attgttacct tgattatttc cattccttta tcaactggag
      301 ctgggattta cttggctgaa tatgccaaaa aagggcctgt taccaacttt attagaacct
      361 gtattgagat tctgtcttcc ctaccatctg tggttgtggg gctctttggt tacttgattt
      421 tcgttgtgca gtttgaatat ggcttttcta ttatttcagg ggctcttgct ttgacggtct
      481 ttaatcttcc tcaaatgacc cgtaatgttg aagatagttt attgcatgtt catcatactc
      541 aaagagaagc aggattagct ttaggtctgt cacgctggga aacagttttt tatgtggtta
      601 tcccagaagc tctcccggga atggtaacag gtattgtctt agcttcaggt cgtatttttg
      661 gtgaagcggc agcgcttatc tatactgctg gtcaatcagc accagctctg gattggtcga
      721 attggaaccc acttagtgtt actagtccaa tctctatttt ccgtcaatct gagacccttg
      781 ctgttcatat ttggaaagtc aatagcgaag ggacaattcc agatgctact cttgtatccg
      841 caggaagtgc agcagtgcta ttaattttta tccttatttt caacttttca gctcgcttta
      901 ttgggaagaa acttcattct aaaatgacag cagcgaaata agatattgga gaaatcatga
      961 cagaatacaa ttggaatgaa cgtcatatca tcacttttcc tgaagaaacg cttgctctag
     1021 ctaccaagga tttacatgtt tactatggtg cgaaagaagc tatcaaaggg attgatatgc
     1081 agtttgaaaa acataaaata acagccttga ttggtccatc tggttgtggc aaatcaactt
     1141 atcttcgtag tcttaaccgc atgaacgata ccattgatat tgctcgggtt acaggtgaga
     1201 ttctttatca gggcattgat gttaatcgaa aagacatgaa tgtttacgag attcgcaagc
     1261 acttaggaat ggtttttcaa agacccaatc ctttcgctaa atccatttat aaaaacatta
     1321 cctttgccca tgaaagagct ggtgtgaaag acaaaaaagt tttagatgaa attgttgaga
     1381 cttcactgaa acaagccgcg ctttgggatc aagttaaaga tgaccttcac aaatcagcct
     1441 tcaccttatc agggggtcag caacaacgct tgtgtattgc tagagccatt tctgtcaaac
     1501 ctgatattct attaatggat gaaccagcct ctgcccttga cccgattgca acgatgcagc
     1561 tggaagaaac catgtttgaa ttgaagaaga attacacgat tattattgtg acccacaata
     1621 tgcaacaagc agctcgtgcc agtgattaca ctgccttctt ctatttaggc aacctcattg
     1681 aatatgataa gacacgtaat attttccaaa atgcgcaatg tcagtcaaca aacgactacg
     1741 tttcagggca ctttggttag aaaggcaata tgatgacaga acctatttta cagatcagag
     1801 acctttctgt ttactacaat caaaagaaaa cgttaaaaga tgtctctttg gacctttatc
     1861 caaatgaaat aacagcttta attggtcctt ctggatctgg gaaatcaacc ctcttgcgtt
     1921 ctatcaaccg tatgaatgat ttgaatcctg aagtaaccat tacaggctct atcgtctata
     1981 acggacacaa tatttatagt ccaaggacag atacggttga tctacgcaaa gaaattggta
     2041 tggtattcca acaacccaac ccatttccga tgtctattta tgagaacgtg gtttacggcc
     2101 ttcacttaaa aggtatcaga gataaatcaa tcttagacca tgctgttgaa agctctctta
     2161 aaggggcttc catttggaat gaagtcaaag atcgtttaca tgattctgcg gttggcttat
     2221 caggcggaca gcaacagaga gtttgcatag ctagagttct tgctaccagc cccagaataa
     2281 tccttttaga tgaacctacc tcagctcttg atcctatctc agctgggaaa attgaagaaa
     2341 cattattgtt attaaaaaaa gattatacac tggctattgt gacccgctca atgcagcaag
     2401 cctcacgttt atcagatcga acaggttttt tcttggaggg tgacttactt gagtgtggtc
     2461 ctacaaaagc catgtttatg aatcctaagc gtaaagaaac cgaagactat atttctggta
     2521 aatttggttg agaaagacgt atatgattga ccccactgtg tttttattat aatgactaga
     2581 ttgtaggaag aaaaaatcat gttaagaacg aaatttgaag aagaattaga taaattgcat
     2641 aaccagtttt attcaatggg aacggaagta ttggcacaaa tcaataaaac tgttcgtgcc
     2701 tttgttagtc atgatcgtga attggccaaa gaagttatcg aagaagatga cactattaat
     2761 aattttgaga caaagcttga aaagaaatcg ctggaaatta ttgccctaca acagccagtt
     2821 tcgaatgatc ttagaatggt tattactgtt ttaaaggcat caagtgatat tgaacgtatg
     2881 ggtgaccatg ctgcttcgat tgccaaggcc actattcgta tgaaaggtga ggagcgtatt
     2941 ccagtggttg aagaacaaat caaccttatg ggaaaagctg tgaaacagat ggtagaagaa
     3001 gcccttaatg catatatcaa tgctgacgat acaaaagctt atgaaatcgc agcttctgat
     3061 gagattatcg atcaatattt ccgtaatatc caaaccttag ctgttgaaga aatccgtaag
     3121 tctccagatg ctgtttttgc aggaaaagaa tattttcaag tattaatgta tttggaacgt
     3181 attggtgact atgctcgcaa catttgtgaa tggattgttt atcttaaaac tggaaaaatt
     3241 attgaattat aagaaattat gctataatga gactggtaaa cagcttgcca gtccctggtt
     3301 ttatacgaaa ttgtgcaagt tagaaaatga actaacaaga aaagttttct ttgctgaatc
     3361 tgattttgtt aggttaacaa atatatgtag acagagatga tacttaggta tcatctgttg
     3421 atctattata atttgttatt agaattaagg agttatatga agacagtaga acatctcatc
     3481 gaaacatttg tgcctgaaaa ttataacatc tttttagata ttaatcgtca gactaaaaca
     3541 tttacgggga atgttgcgat taatggtgaa gctttagata atcatgtggc tttccatcaa
     3601 aaagatttgg acattaagtc tattttgctc gataatgaag ctgttattta tcaagtggat
     3661 aacgacaatg aagttgtgcg tgttgaatta cctgaaacag gaatgatgac gcttgtcatt
     3721 gaattttcag gtagcattac agataatatg acaggtattt acccttcata ttacactaaa
     3781 aatggtgaga aaaaagaagt catttcaact cagtttgaaa gccattttgc acgtgaagct
     3841 ttcccatgta tcgatgaacc acaagcaaaa gctacttttg atttaagctt gacctttgat
     3901 caagaaattg gtgagatagc gttatcgaat atgccagaag tcaatattga ccgtcgcgag
     3961 gagactggtc tttggacatt tgatacgaca ccaagaatgt catcttactt gctagcgttt
     4021 gcgctaggag aacttcatgg aaagactgta gaaagcaaaa aaggaacaac tgttggtgtg
     4081 tatgcgacaa cagcgcatcc tcttagctcg cttgattttt cattggatat tgcagttcgt
     4141 gttattaact tttatgaaga ctattttgga gtacattacc caatcccgca atctcttaat
     4201 attgcgcttc cagatttttc atctggtgct atggaaaatt ggggtttaat cacttatcgt
     4261 gaaatttatt tattagtaga tgaaaattcg actgttcaaa gccgacaaca agttgcactt
     4321 gtaatcgccc acgagatagc acaccaatgg tttggaaact tggttacaat gaaatggtgg
     4381 gacgatctgt ggttaaatga gagttttgcc aacatgatgg aatatgtctc tatcgaggct
     4441 attgagccgt cttggaaaat aatagaagat ttccaaacag gcggtattcc tcttgcttta
     4501 aaacgtgatg ctactgatgg tgttcaatca gtgcatgttg aagtcaatca tccagatgaa
     4561 ataaatacat tgtttgatcc tgctattgtc tatgcaaaag gtagtcgttt gatgcatatg
     4621 ttacgccgtt ttattggtga tcgtgatttt gccattggct tacatcacta ctttgaaaaa
     4681 tatcaatatc gaaatactgt cgggcgtgat ttatggaata ttttatcaga tacttcaggc
     4741 aaagacgtag ctgcttttat ggatgcttgg cttgaacaac caggttatcc agttttaaca
     4801 gctcgccttg aaaacgatca attgattttg agtcaaaaac aattttttat tggaaaaggt
     4861 gaagaaaaag gtcgcctttg gccgattcct ttaaacacta attggcatgg ccttcctgaa
     4921 actttgacag aggcagaaat ggtcattcca aactttagtc aattggcagc agaaaatgaa
     4981 ggagctctac gtttcaatat tgataataca gctcattaca ttacagatta ccaaggatca
     5041 ttattagatg ccttagtcac tgaacttgcc caacttgata atacttctgc tttacaagtt
     5101 attcaagaac gtcgtttatt ggcagatagt ggcttgattt cctatgctga attggttgac
     5161 ttaattgctc aattggacga ttctaagtct tatatggtag cagaagcggt tcagcaagtg
     5221 gtctctggtt tgaaacgctt cattgatgaa ggaagcttag cagaaaaatc ctttaatcgc
     5281 ttggtaacca ccatctatca agaagacttt aatcagcatg gttttgagaa aaaagctgac
     5341 gaatcagatg aagatgagat ggtacgtcag gttgccttgg gacgcttgtg gctagcagaa
     5401 aatcagacga ttattgacgg attgagaact atttttgaag catatcaaaa caatattgca
     5461 agtattccag cagctgttcg tcgcttggtt ttagccaacc aaatgaaata ttttgaaata
     5521 gatagcctgg ttgatattta ttttgagact tatgtagcaa ctactgataa taatttacgc
     5581 agtgatttaa cggttgcttt tagtcaaaca aaacaactaa ctactattag acgtattctt
     5641 gttagtttaa aagataaaga tattattaaa cctcaggatt tatcttattg gtacaatgct
     5701 ttacttggac aaagctttac tcaagatatc atttgggaat gggctagaga aaattgggat
     5761 tggattaaat ctgcacttgg tggagatatg agctttgata aatttgttat ttatccagca
     5821 agtaacttta aaacaccaaa acatctagca gaatataaat ctttctttga acctaagcta
     5881 gatgatatgg ctattagccg taatattacc atgggaatta atgaagttga agcacgtgtt
     5941 gctttgatca ctaaagaaaa agaagcagtt attgcagctc tcagtcatta ctagaccata
     6001 agcaaaagag ttgggggact ttccagctct tttttgtagt gagctagctt cctttcttag
     6061 ttccgtctat aactaagtga ttatccatag tttaattcaa aaggagattg cactttaaag
     6121 cgaaggctat tagcctctta atactttttt taccaggtgg tgaataagaa caattataaa
     6181 tgatttaatc attatgcttt aaatgcctta aaggagtatt aatattttag taaaccttaa
     6241 gctttttgta gtatagtctc gttagaaatt gttatcagaa atgagactaa gttaaatgaa
     6301 gtgatagtta ctttatttaa gaacaattga ggtagagaca tgataaagat attattagta
     6361 gaagatgact tgagcttatc aaattccatt tttgattttt tagatgattt tgcagacgtc
     6421 atgcaagttt ttgatggcga tgaaggttta tacgaagcag aaagtggtat ttatgatttg
     6481 attttgttag accttatgtt gccggagaaa aatggctttc aagtcttaaa agaattgcga
     6541 gaaaaagata ttaaaattcc tgtgttgatc atgacagcta aagagggttt agatgataaa
     6601 ggtcacggat ttgaattagg tgctgatgat tatctgacaa agccgttcta tttagaagag
     6661 ttaaaaatgc gaattcaagc actgttaaaa agaacaggga aatttgcaga taaaaatatt
     6721 agttttggca atttagtggt cgacttagct cgaaaagagg tgaaggttga agggaaagta
     6781 gttgaattac ttggcaaaga atttgatttg ttggtgtatc ttttgcaaaa tcaaaacgtt
     6841 attttaccaa agacacaaat ttttgatcgt ttatggggat tcgatagtga tactacgatt
     6901 tcggttgttg aagtttacat ttctaaaata aggaaaaaat taaaaggtac ccgttttgtt
     6961 aacaggcttc aaactttaag aagcgtaggg tatattctaa aaaacaatga ataaattaaa
     7021 aaaagagatt ttatcagata actataacca cttttttcat ttttttgcgg tttttacagg
     7081 tatttttgtc attatgacta ttattatctt acagattatg cggtttggcg tttattcgtc
     7141 agttgacagt agtttagttt ctgttagtaa taatgcaagt agctatgcta atcgtacgat
     7201 ggctagaata tcttcttttt actttgatac tgaaaataac attattaagg cgctgcctga
     7261 ttcagatagt tctaagttat taggaacgcc tgcagctaat acagatatca ttttgtttag
     7321 tgctaatgga acaattttaa atgcttttga tgcgttttct aactatcaaa attttcattt
     7381 agataaacac cgtttgggga gtattgaaac caccagttta atgaattttt atggacaaga
     7441 agaaaaatac catacgataa ccgtaagggt tcatatcaaa aattatcctg cagttgccta
     7501 tatgatggca gtagtaaatg tggaacaatt agaccgcgct aatgaacgtt acgagcgcat
     7561 tattattata gttatgagtg ttttttggct aatttctatt ttagcaagta tttatttagc
     7621 caagtggagc agaaaaccta ttttagaaag ctatgaaaaa caaaaaatgt ttgttgaaaa
     7681 tgctagtcat gaactaagga cccctttggc ggtcttacag aatcgtctgg aatcgctttt
     7741 tcgtaagccc aacgaaacga tattagaaaa tagtgagcat ctcgcttcta gtttagacga
     7801 ggttcgcaac atgcgcatct taacaactaa tttattaaat ttagcaagac gagatgatgg
     7861 cattaatcca cagtggactc atttagatac agattttttt aatgctattt ttgagaatta
     7921 tgaactagtt gctaaagaat atggaaaaat attttatttt cagaaccaag tcaatagatc
     7981 gttaagaatg gataaggctt tactaaaaca attaataacg attttatttg acaacgctat
     8041 taaatataca gataaaaatg gtattattga aattatagtg aaaacaacgg acaaaaattt
     8101 attaatttct gttattgata atggtccagg gataacagat gaagaaaaga aaaagatttt
     8161 tgatcgtttt tatcgagttg acaaagctag aacacggcaa acaggtggat ttggcttggg
     8221 gttggcttta gctcagcaaa tcgtgatgtc tttaaaagga aatattacag taaaggataa
     8281 tgatcctaaa ggtagtattt ttgaagtcaa actataagct aaaaagggcg accaataagg
     8341 tcagcccttt taaagttatt tttaactgtc aacgctttat tgtatttttt gagtttttac
     8401 cgtataaaaa aactccagct ggagttttca ttggatattt attagccaag ttttgcagca
     8461 aggcgtgctt tatcgcggct tgctttgttt ttgtgaatca aaccttttga ttcagcttta
     8521 tcgatgcttg aagaagcagc gcggaaaagc tcttcagatg ggttagcttc aaatgctttg
     8581 atagcagtac gcatagctga tttttgtgct gagttttttt cgtttgcttt aacgttaagt
     8641 tcagcgcgtt taatagctga tttaatattt gccaatgttt tcacctccaa attaatctaa
     8701 ctacattatt atatagaaaa tatatgcgtt tggcaaccct ttatcacttt ttgaggtaaa
     8761 tttcatcaat tttatgatca gcacttttat gtaaaattaa ttcagcacgg ttacgtgtag
     8821 gttcaatgaa tttttcaaga ttttctaaat taacggtttt ccaaacgttg cgcgcaaatg
     8881 ctatagcctc agatcgaggt aattgtgcat attgggcata ataattatga gggtcacgtt
     8941 ttgctaattt taaaatgctt agaaaccgtt caatgtacca ggtttcgatg tgactgctgt
     9001 ctgcatcaat ataaatagaa aaatcaaagt aatcactcat atataaacga ttgttttgtt
     9061 gattttgaaa aacattaata ccttcgacga taaggaagtc agggttatta aatgattgtt
     9121 tttgatttgg gataatatcg taaatatcat gagaatagac gggtgcaaaa gcagtttgac
     9181 catttttgat ggaatctaga aaatctaaga gaagttccat gttataagat tctggaaatc
     9241 ctttacgatt taacagtcct tgttcaataa gaaactgatt aggatataaa aaaccatcag
     9301 tcgttaccag ttcgacttga ctattggggt gcgttcgtga taataaaagt tgtaaaagac
     9361 gactagttgt tgatttacca acagctactg aaccagaaat tccaataata aaaggtctta
     9421 attgaatgtc tttttttaga aaaaggcttt tagaaaaaga aagattttct tgcgcaattt
     9481 tgtaaacctg gatcagatta attaatggaa ggtagatatc aatgacatcg ttaatactga
     9541 tgttatcatt taagctagta atacttttaa gttcctcttg tgtgaggaga gcttttgcct
     9601 tttgatgtaa tgttttccaa gactctctag aaattttttc aaagttgata aattcatttg
     9661 acatggtagc tcctaatcat ttgacagtgc ttacattata ccattttagt taaaaaatta
     9721 ataatttttc gttagtattt acacgaaaat taatacaatt aactcaaaaa agccacacat
     9781 tcctagtaca attatcctgc tatattctaa caaatagtta aagttcggtt tttatttgta
     9841 atatagagaa aattgttaag aaacaagcgt cttgtaaacc atttcaaagt atgatagaat
     9901 gaaaaagtac cttaaaaaga taggaaaaat gatgacaaag atgtattatg atgaaaatcc
     9961 agatagccta cacgatattc atgaagtaaa agtagagctg cttaatcatc cctttacttt
    10021 tttaacggat tcaggtgtct tttcaaagaa aatggttgat ttcggtagtc aagtattatt
    10081 agagacacta aatttcaagg agaacgaacg tgtactggac ttaggttgcg gctatggtcc
    10141 tcttgggatt agtctagcca aggttcaaag ggtagacgca accttagtgg acatcaataa
    10201 tcgtgctctt gatttagcta gaaaaaatgc aactaataac caagtggcag taactatttt
    10261 tcaatcaaat atttatgaaa atattagtgg ccattttgag catattatta gtaatcctcc
    10321 tattagagca ggaaagagag tagttcatag cattattgaa aaaagcatag attttttagt
    10381 ggttaatggt gacttaacga ttgttattca aaaaaaacaa ggagctccta gcgctaaagc
    10441 aaaaatggca actatttttg gtaatgttga gatattaagg aaagataaag gttattatgt
    10501 attaagaagt ataaagcaag cctaatttaa ataatcaaca attgctcatt taaattaggt
    10561 ttgcttaata tagtaaagag ttatttttaa attatagata actaatatta tactagggta
    10621 gcccctctac tcgagtaacc ttttttaatg tattttaact gaaaaaggct ttcataattt
    10681 taaaaaaatg ttaaaatagg tgtataacaa ctgattacca agagattatt atcattatct
    10741 tctaaggtgt cattgttatg gtgacaatca accatacgct actaaagata ggtagcgttc
    10801 gatcacaggt tgatcaagtg attgaaaaat caatatttat aattttacaa atatctgtat
    10861 caatccatgt tgaatagtct atgcttctaa ggtgtcgacg ttaatgtact gacgggaccg
    10921 ttatagtctt tctttttgga gaaacgtcgg atgccagtga actagttgaa gttaaagatg
    10981 ttaattcaaa cagtgctgaa gagattgata tcgttttgaa cggtcgttta cttcaaagca
    11041 aagaaattac cagtctatcg aagatgatat aagtgctaaa gttagatcac gttaattatc
    11101 tatcaagtcg ggtgcatatt tcgttaaagt atctacaggg gtttcaatag atgtagctat
    11161 tatgaaaggt gatgttaaat ggggactact gatttagtta gttgtgctgt acaagctagt
    11221 gagtatgctt atgtccctta ctctcatttt ccagtaggag cagctttaaa aacaaaagat
    11281 ggaacgatct atactggctg taatattgaa aatgttagtt ttggtctgac aaattgtgga
    11341 gagcgaacag ctatatttaa agccatatct gatggtcata aagaattggt tgaaattgct
    11401 atttatggag aaactatgca acctgtatct ccttgtgggg cttgtcgtca ggtaatggca
    11461 gaattttttg ctccttcttc tttagtcact ttaattgcta aaaatggtca aactgttgaa
    11521 atgactgttg gagatttact cccctattct tttacagatt taatataatc tgctttaatt
    11581 tctgttatct agccgtcttg gctttatatt tactttcagc aacttatttg ctagaaatct
    11641 tttttaggag ggttcatatt catgaacaag aaatttatta gtcttggttt agcgtcagtg
    11701 gctgtgctga gtttagctgc ttgtggtaat cgtggtgctt ctaaaggtgg ggcagcagga
    11761 aaaactgatt taaaagttgc aatggttacc gatactggtg gtgtagatga taaatcattc
    11821 aaccaatcag catgggaagg cctgcaatct tggggtaaag aaatgggcct tcaaaaagga
    11881 acaggtttcg attattttca atctacaagt gaatctgagt atgcaactaa tctcgataca
    11941 gcagtttcag gagggtatca actgatttat ggtatcggct ttgcattgaa agatgctatt
    12001 gctaaagcag ctggagataa tgaaggagtt aagtttgtta ttatcgatga tattatcgaa
    12061 ggaaaagata atgtagccag tgttaccttt gccgaccatg aagctgctta tcttgcagga
    12121 attgcagctg caaaaacaac aaaaacaaaa acagttggtt tcgtgggcgg tatggaagga
    12181 actgtcataa ctcgatttga aaaaggtttt gaagcaggag ttaagtctgt tgacgataca
    12241 atccaagtta aagttgatta tgctggatca tttggtgacg ctgcaaaagg aaaaacaatc
    12301 gcagcagctc agtatgcagc aggtgctgat gttatttacc aggcagcagg aggcactgga
    12361 gcaggtgtat ttaatgaagc aaaagctatt aatgaaaaac gtagtgaagc tgataaagtt
    12421 tgggttattg gtgttgaccg tgatcaaaaa gacgaaggaa aatacacttc taaagatggc
    12481 aaagaagcaa actttgtact tgcatcatca atcaaagaag ttggtaaagc tgttcagtta
    12541 atcaacaagc aagtagcaga taaaaaattc cctggaggaa aaacaactgt ctatggtcta
    12601 aaagatggcg gtgttgaaat cgcaactaca aatgtttcaa aagaagctgt taaagctatt
    12661 aaagaagcga aagcaaaaat taaatctggt gacattaaag ttcctgaaaa atagtgttta
    12721 agaacaagaa gcgcgacctt tgtcggtcgc tctttttaaa ctgagataat ttttatctca
    12781 gtaaagtttg tgataggtga tagatcatag gctttactga aataaaagat tgcattgaaa
    12841 ggaaatgatc ctatgacaca gcatgtcatt gaaatgagag aaatcacgaa aaaatttggt
    12901 gattttgttg caaatgacca cattaactta aatgtcagaa aaggtgagat tcatgcctta
    12961 ttgggtgaaa atggggcagg taaatcaact ttgatgaata tgctagctgg tctcttagag
    13021 cctactagtg gagaaattgt cattaatgac aagccagttc aaattgattc gccatctaaa
    13081 tcagctaagc ttggtatcgg aatggtacat caacatttca tgttagtaga agccttcacg
    13141 gttgctgaga atattatttt aggaaatgaa gtagtaaaaa atgggtgctt agatcttaac
    13201 caagcatcga aagatattaa ggtactatcc gaaaaatatg gccttgcaat caatccatca
    13261 gctaaagttt ctgatatttc agtaggagca caacaacgtg ttgagatttt gaaaaccttg
    13321 tatcgtggtg cagatattct tatctttgat gagccaactg ccgttttaac acctgcagaa
    13381 attaaagaat tgatgactat catgaagaat ctcgtgaaag aaggaaaatc aattatttta
    13441 attacccata aactggacga gattcgtgct gtcgccgacc gtgtcacagt tattcgtcgt
    13501 ggtaagagta tcgaaacagt tgatgtggca ggagcaactt cacaagattt agctgagatg
    13561 atggtgggac gctcggtttc ctttacaact agcaaaaaag ctgctgaacc aaaagatgtg
    13621 gtcttatcca tcaaaaatct tgaagtagat gaaaatagag ggattccagc ggttaagggg
    13681 ctatctctag atgtccgagc tggtgaaatt gtagggattg ctggaattga cggaaatggt
    13741 caatctgagt taattcaagc tattacaggt ttacgtaaag tcaaatctgg aagtattatg
    13801 attaaaaaca atgaagtcac tcatttgtct tcacgcaaaa ttactgagtt atcagtgggt
    13861 cacgtgccag aagatcgtca tcgagatggt ttgatactag atctttcttt agctgaaaat
    13921 acagccttac aaacctatta caaacaacct ctaagtcaaa atggtatctt aaattatact
    13981 aaaattaatg actatgctcg tcaattaatg aaagaatttg atgttcgcgg agccaatgag
    14041 ctagtaccag ctagaggatt ttctggtggt aaccaacaaa aggccattat tgctcgtgaa
    14101 gtggaccgtg atccagattt acttattgtt agccaaccaa cacgtggtct tgacgtagga
    14161 gctattgaat atatccataa gcgtttgatt aaagaacgtg ataaaggtaa agctgtcctc
    14221 gttgttagtt ttgaacttga tgaaatattg aatttatctg atcgaattgc tgttattcat
    14281 gatggtaaaa ttcaaggtat cgtattgcca gaaaatacca ataaacaaga attgggtatt
    14341 ttaatggcag gtggttcaat tcataaggag gaaggtcatg tctaaaaatg cgcaaaaaat
    14401 tgctgtacca ttgatttctg tcttgctagg atttttactt ggcgctatta ttatggttat
    14461 ctttggttat gatcctatct gggggtatga aggtttattc caaattgcct ttggtagtgt
    14521 taaaaatatt ggagaaatat tccgttcaat ggggccattg attttaatag cgcttggctt
    14581 tactgttgct agccgtgcag gcttctttaa cgttggtttg tctggacagg ctttagctgg
    14641 atggatttca gcaggttggt ttgcactctt aaatccagat atgcctcgtc cattattgat
    14701 tcttatgaca gctcttatcg gaatgattgc tggtggtatt gctggagcta ttccagggat
    14761 acttcgtgct tatcttggta caagtgaagt tatcgttacg attatgatga actacatcat
    14821 tttatatgtc ggaaatgcta ttgttcaacg tggttatcct gagagtgtca aacaaagtat
    14881 tgattcaact attcaagtta gtgataatgc tagttatcaa acgcattggt tatcagccct
    14941 aactaataac tctcgtatta atattggtat tttctttgcc attattgcca ttgccctaat
    15001 ctggttcttg cttaacaaaa ctactttagg ttttgagatt cgttcagttg gtctcaaccc
    15061 acatgcttca gaatacgcag ggatgtcatc aaaacgtact atcattttat caatgattat
    15121 ctctggagct cttgcaggtc ttggaggagt agttgaaggt ctaggaacct ttgaaaatgt
    15181 ttttgtacaa ggatcttctt tagcagttgg ttttgacggt atggcagtta gcttattagc
    15241 agcaaattca ccgcttggaa tatttttctc atcattccta tttggtgtct taaatattgg
    15301 tgctccagga atgaatattg caggcattcc accagaactt gttaaagtag taactgcatc
    15361 aatcattttc tttgttggtt cacattacct cattgaacgt tacattattc gccctaaaaa
    15421 attagtgaaa ggtggtaaat aagatgagtt tagtaacaat ttttgcctta ttggtgtcat
    15481 ctatgcttat ttatgcaaca ccactcattt tcacaagtat tggaggaact ttctcagagc
    15541 gctcaggcgt tgttaatgtt ggtttagaag gtatcatggt catgggagcg ttctctggga
    15601 ttgttttcaa cttagagttt gctgaaacat ttggaaaagc aacgccttgg atagccgttt
    15661 tagtcggtgg tattgttggt ttgatttttt ctttgattca cgctgtagca accatcaact
    15721 ttcgagctga ccacattgtc agtggtacag tgttgaactt gttagcacct tcttttgctg
    15781 tcttcttggt taaagctatg tacggtaagg gacaaacaga caacattcaa caatcttttg
    15841 ggaagtttga tttcccaggt ttatcacaaa ttcctgtgat tggtgatatt ttctttaaaa
    15901 atactagcct tattggttac ttcgccattg ctttttcgtt ctttgcttgg tttttgcttt
    15961 ataaaaccag gtttggtctg cgtttacgat cagttgggga acaccctcag gcagctgaca
    16021 cacttggtat taacgtctat ttgatgaaat actatggtgt gatgatctca ggttttcttg
    16081 gtggaatagg tggagctgtt tatgctcagt caatctccgt taactttgct gtaacaacta
    16141 tcttaggtcc tggatttatt gctttggcag ctatgatctt tggtaaatgg aatccagttg
    16201 gcgccatgct atctagtctt ttctttggct tatcgcaaag tttagccgtt attggtgctc
    16261 aattaccatt actagaaaag attccaacgg tttacttaca gattgcacct tatatggtaa
    16321 cgattattat tttagctgct ttctttggtc aagcagttgc accaaaagct gatggaatca
    16381 actatattaa atctaaataa cgttatatta gtagtaagcc tcttagtgag gtttaacagc
    16441 actcctaaag caagatagtt aggtctagct ttaagggtgc ttttttggga cttaccgcaa
    16501 gcgtttggat tgccagtcac catcacaata gaagcaagaa tagactaaaa agaactaagt
    16561 cagcggctta gttctttttg cttgtctttc gtttttaccg atagctctta agttgtttta
    16621 gccaacaaag gtattgattt ctgtttcaat gttagcaatt ttttcttgag cgatgtcaag
    16681 agtatcacct attgtggcaa tatagaactt gatttttggt tcagttcctg aagggcgaac
    16741 tgcaatccat gaatcatcag ctaacgtgta cttcaaaaca ttacttggag gagttgttaa
    16801 gttagatatt gttccatcat ttttagtagc ggtttgtttt tggaaatctt ctaataatac
    16861 aatatcagta ttgtcaaatt gttttggacc attttcacgg aatttgtcca taatcttctt
    16921 aatttcagca gctccatcca cacctgaaag tgttactgaa atcgtttttt cagcaaaata
    16981 gccatattct ttgtaaattt catcaatacc atctgcaagt gttaaaccac gcgaacggta
    17041 ataagctgcg atctcagcaa ccaaaagaac tgcttgaata gcatctttat cacggacaaa
    17101 tggtttaata agatatccga agctttcttc aaaaccaaac atataggtgt ggttatgttt
    17161 ttcttcaaac tcttgaattt tctcagcgat gaatttgaat ccagttaaaa cgttaaacat
    17221 tgtagcgcca taactttcgg caatttttgt tactaattct gttgatacga ttgatttagc
    17281 gagagcagca ttttctggaa gtgttcctgc tgttttatga gcttccagga tgtatttcgc
    17341 aataatcgct ccaatttgat ttccagaaag gtttttataa gaaccatctg gttggcgaat
    17401 ttcaacgcct aggcggtctg catcaggatc agtagctact aagacatctg catcaacttc
    17461 tcgtccgagt tcttcagcaa gagcaaaggc agcttggctt tcagggttag gcgatttaac
    17521 agtagaaaag tctggatctg ccttagcttg tgattcgact acaacaacag attcaaaacc
    17581 ggcttgagca agggcacggc gtgtcaacat ctcaccagtt ccatggagag gagtatagac
    17641 aattttcatg tcttttccaa agttattgat taaaacttga ttgatattaa catctttaac
    17701 ctctctaaga tattccatat caacatcttc accgataact tgaataagac ctgatgattt
    17761 gctttcatct aaatcagcaa gttcaactgc aaatggattt tcaatagcac ggataaagtc
    17821 tgttagtgca tcagcatcag ctggtggtag ttgacctccg tcttgtccat agactttata
    17881 accattgaaa ggtgctggat tgtggcttgc agtaaccata ataccagcat aggcatttaa
    17941 atggcgaaca gcaaaagaga gttctggtgt tggacgaaga gcttcaaata cgtaagattt
    18001 aatcccatgc tgtgccaaga cctgtgcaga ctcaaaagca aattctggag agaagtggcg
    18061 cgaatcataa gcgatggcta caccacgttt tttagcttcc tctcccttag tttcgattaa
    18121 ttttgctaat ccttcggttg cttgacggac aacataaata ttaatacgat ttgtaccagc
    18181 accaatataa ccacgcatac cagcagtacc aaattctaag tttgtgtaaa aagcatcttc
    18241 ttttgttttt tcatccattg atagtaattc ttgacgaaga tagtcaggaa gctgctcaaa
    18301 atctaaccat ttttgaaaat tttctgtgta agtcattgaa atactccttc aatatttata
    18361 aacgctttca ttatatcatt ttgaaggaaa aaaaacacta attatttgca gctgtttaca
    18421 aaactttttc catattttca agtagctaat gtaagaaagt taaaataacc aagtttttaa
    18481 aagagaaaaa ctcggttatt gtgaaagcta attacctttt tagtcttgat agtgttggaa
    18541 taagtacaaa agtaataata gctgagatga tcatctcaac aatagcgttt gatgagatga
    18601 tggctgttag tagtgcttta atatttccat caaaaactgt cgcgaaaaaa ataaatatcc
    18661 cagataatac aaatatagta tttgttagag aaccaatgat accggatact attaaaccaa
    18721 actgattagg aatcaattta tagcaataat aaggggtaat accaatcaaa atacgtggga
    18781 taatagcaat tattaaagaa gcgaaagttc catgatcgac aaaaggtgaa aagagataat
    18841 ttgtaggcag tagaatgatg gtatttgtaa tgacacttat aatccccatt aatcctccta
    18901 aaatagcacc tatccttggg ccatataaga cagaagcaat aataactggg atatggacaa
    18961 gcgttggttt gattggaatc ggccaaatat taaagacaag actgctcaca aaatgaatga
    19021 ctaacatgat ggcaaaaaag atagcaatac gagaaatatc tgctgattta cggtgattca
    19081 ttttactctc caaaaaatat aatacttaat tctaaaaagg tgatcagaaa aacgactgtt
    19141 aaagtttcca aatcgtatca atagtagcta agataacatc aatatcagcc aaagcaccaa
    19201 gtcctttatc tccacaggct aataagctag attttggagg aatttctgta aaccctattg
    19261 tcgataagcg tttaatattt tcttgggtaa tagggttttg atacattttg gtattcatgg
    19321 ctggggctat taattttggt gtggtagctg gtagggcaag agcaacactt gttacaatat
    19381 tatcagcgaa tccatatgct agatgagcaa tagtattagc agaggcaggt gcaacaataa
    19441 ataaatctgt gcgttttgct aattcgatat ggttgataac ttttgggtca tgctcatcca
    19501 taacatctaa atgaatagca ttttttgata acacttgcag ggttaatggt gtaataaatt
    19561 gtgtagcagc ctgagtcatt atgatgtgaa catcatagcc cattttagtt aattgactcg
    19621 taagatctgc tgctttatag gcagatatac taccagaaac agctaaggta atatgtttag
    19681 tcatgtttgg tcatcctttc atataataag tcagcaattg cctctttggt atctgcagat
    19741 gcaacttcgt tattggatat caaaagagcc ttgtgcatac ctgtttggat atcaactaaa
    19801 tcattggcga gaatataatc agcatggttt ttaactagac ttgctctggc tactttaatt
    19861 aactcttctt gaggcacatt aactagaagt ttaaagccga ctagtttaat attaggattc
    19921 cactgtttaa cataagagat aactttgggt gtttttttca aaaaaagaac ctgataatca
    19981 gatgcagatg agattttcgg ctcactgtta tgttcacata gaaaacaatt aaggttatca
    20041 gcttgagaga cttgttccaa atcagtcatg tagactggag tatagtcaga aacagccata
    20101 ctatgaatta gaatgtcatg gtgaggaacc tgatctttga gtgcagccat taagtcgtta
    20161 actgtttcca cttcaataat ccttaggcgc tcatttggca ggggtttagt ggctgtttta
    20221 gtagtgacta gggtaacgtc atgatgatat tgtaaaaatc gctctgtaat taattttcca
    20281 agttgcccag ttgagtgatt agtgatacct cgtactgcat ctataggttc agttgttcca
    20341 cctgatgtta ttattaattt catagtcata ttttatcaaa aaaggagctg atagtaaacg
    20401 gaagataatg acgccagaca ttgtcttgcg tttgtattaa tatggaatag taatagattt
    20461 ctagtaatta aaacgaagtt ctggaaagca agacactata gtagctaaaa tctaaatttt
    20521 aaggtaaaat agagcaagcg gtttcaagtg tgaaaggaag aattgtgata actattagag
    20581 atttagcgtc actgccgatt tttgtttacg gtgatggaaa taaaaaagtt ccaggagctt
    20641 tgagtccttt tgtgtggaca gaggtgtttt taaaaactat caatcaagaa cctaatcaac
    20701 tgatcttaca tatttggccg atgacaagaa cagttatatt aggaatgtta gatagacagc
    20761 ttccctactt tgagctggct aaaaaagaga ttggcaataa tggttatgtt cctgttactc
    20821 gtaatattgg cggtttggct gttgtcgctg atgatgggat tttgaatttt tcgcttgtta
    20881 ttccagacca tttttcggaa tctatcagta ttagtaatgc ttatctaata atggttgatg
    20941 tcattagaga gagtttttcg gattattatc agcgtattga atatcacgaa attaaaaatt
    21001 cttattgtcc tggtaatttt gatcttagta ttgcaggccg caagtttgca ggtatcgccc
    21061 agcgtcgtat caaaaaggga attgttgtgt ctatttactt gagcgtttgt ggggatcaag
    21121 cagcgcgtgg tcaactcatc aaggcttttt atgaggctgg aacacaagga gaagttacca
    21181 aggttaatta ccctcaaatt gatccagaat gcatggcaac tctttcagaa ctccttgaga
    21241 cgccttttac agtggcagaa gttcttgaac gtcttcggtt gaccttgcga cagcttggct
    21301 tttccctcac ggaaaaaagt ccagatcaag ccttactgac taattttgat gctgtctatg
    21361 aacggatgca gctagaagtc gttagaaagg aaggcaaatg aaagaaagat ttagtccttt
    21421 atttgagctt ttgactttgc caaatgggag tcaattggat aatcgctttg ttttgtctcc
    21481 tatggtgacc aactcatcca caaaagacgg ttatgtcacc caagatgata tatcctatgc
    21541 tttgagacga gcagcttctg cccctctgca aattacagga gcggcctatg tggatcctta
    21601 tggtcaattg tttgaatatg gttttagtgt tacaaaagat gccgatattt ctggcttgaa
    21661 agagctagct caagcgatga aggcaaaggg agctaaagct gtcttacaac tgacccacgc
    21721 tggccggttt gctagccatg ccttgactaa atatggcttt gtctatgggc ctagttacat
    21781 gcagttgaga tctccccaac ctcatgaagt caaaccttta acaggtcagc aaatagagga
    21841 attggttgca gcttacgctc aggccactcg gcgggcaatt caagcaggct ttgatggcgt
    21901 ggaagtatct tcggcgcagc gcttattgat tcaaacgttc ttttcgactt tttcgaacaa
    21961 gaggacagat agttatggtt gtcaaacact ttttaatcgc tctaagttaa ctttagctgt
    22021 tttgcaagct gttcaacagg tgattaaaca agaagctcct gatgggttta tttttggatt
    22081 tcgtgctaca ccagaagaaa ctaggggaaa tgatattggt tatagtattg acgagttttt
    22141 gcagttgatg gattgggtac ttaatgttgc aaaacttgat tatttagcga tagcaagttg
    22201 gggccgtcat gtatttcgaa atactgttcg ttctcctggc ccttattatg gaaggcgagt
    22261 taatcaggta gttagagatt atttaagaaa taagctacct gttatggcta cagggggaat
    22321 gaacacacct gacaaagcta ttgaagcact agctcatgct gattttattg gagtatctac
    22381 accttttgtt gtggatccag aatttgctca taaaatcaaa gaagggtgtg aagagagtat
    22441 tcatttaagg attcgacctg ctgatttgaa aagtttagcg attcctcagg cttctttcaa
    22501 agatattgta cctttgatgg actacgggga atcattgcct aaagaatcaa gaactttatt
    22561 tcgtagtctt actcacaatt ataaggagat taaatgaaag tcagtattct tgattatggg
    22621 gtgattgata aagaaaaaac atcccaagaa gctttattag aaacgcgctg tttagcacaa
    22681 gtagccgaca aacttggctt tcatcgtttt tgggtagcag agcatcataa tatttatgcc
    22741 tttgcaataa gcagtccaga gctgttgatg atgcatttag cagatcatac caaacagatt
    22801 cggataggtt caggaggtat tatgcctcta cattatagta gctttaagat tgcagaatgg
    22861 ataatgactt tagaggcctt gcaccctaat cggattgatt taggtattgg caactcttta
    22921 ggaactacgt tagttcaaag agctctatca agtatccatt gcaaagacag ctatagtcag
    22981 gttgtcacag aattatacca gtatcttaat cctgatcatt tgtcaccact accgattttt
    23041 gttaacccta ggggtaatac ttaccctcag atttggacgc taagcaatag tttggagaca
    23101 gcagaactgg ctggtcaatt aggtttaggc tatacctttg gtattttccc ctatatacca
    23161 aaagatccta taacagaagc taaaagagta tcggcacatt atagaaaggc ttttaggcct
    23221 tcaaagctat taaaaatccc caagttaata ttagcagttt ttattgtcct ttctgatacc
    23281 gacgaggaag cagaagcttt ggctaaaccg ttggacattt ggatgcttgg tcagcaagat
    23341 tttaatgaat ttaagaccta ccctgatgtt gaggaggcta gaaactatca cttaacagag
    23401 aaacaaagag aagccattgc agcaaatcgt agtcgcatgg ttattggacc acctcacaca
    23461 gtcaagaaac aattggatag gctgatagaa gcttgtcaag ctgacgaatt attagccatc
    23521 cccttagttc ctgaatttgc caatagacaa cgaaccttag agctgctagc agacttatac
    23581 gtgaccattt aaccttacca aaaacaattc cctaaactga aaggaaagaa acaatgaaaa
    23641 aaattgcaaa ttacttatta attgagaaaa cagatgaccg ctataccatt agcatgacac
    23701 cagaattaca agacgatatt ggtactattg gttacgctga atttacggat aacgaccacc
    23761 ttgccgttga tgacattatc ttaaatctag aggcttctaa gaccgtcatg tctgtcttgt
    23821 caccattggc tggggcagtt gttgagcgca atgaggcagc cacactaaca ccaacccttt
    23881 tgaattcaga aaaagctgag gaaaattgga ttgttgtgct aacagatgtt gatcaagcag
    23941 cttttgatgc cttagaagat gcctagttca tttgatttat taggggaaat gattggtctg
    24001 ttgcaaacag agcagcttac tagttcttta gcctgtccct tgcctaatgc tttaacaaag
    24061 cgacaagact tgtggcgggc gctcattaac cagcgccctg ctttgccttt atcaaaagat
    24121 tacttgaatc tggaagatgc ttatctggat gattggcgtg cttcttttgt tcctgtatca
    24181 gtcaaggatt gccaaaaaac taattatacc agtctttttc tttaccatgg ggatattagg
    24241 taccttgctg tggatgctat tgtcaatgct gctaatagtg agttattggg atgttttatt
    24301 cctaatcatg gctgtattga taatgcgatt catacgtttg ccggaagtcg tttacgctta
    24361 gcttgtcagg caatcatgac tgaacaaggc cgtaaggaag ccattggcca agcaaagctt
    24421 accagtgctt atcatctacc agcctcttat attattcata ccgtagggcc aagaattacc
    24481 aaaggacgac acgtttctcc gattcgagct gatttgttag cacgttgtta tcgttctagt
    24541 cttgatttgg cggttaaagc aggattgact agcctagctt tttgctctat ttcaacagga
    24601 gaatttggct ttcctaaaaa agaagccgct cagattgcca ttaagacagt tttaaaatgg
    24661 caagcagaac atccagaatc taagacttta actgtcattt ttaatacctt tacatcagaa
    24721 gacaaggcct tatacgacac ttatttgcaa aaggagaata actgtgagta attggacaac
    24781 ctatcctcag aaaaatctca cccaggcaga acaactggcc caattaatca aagaagcaga
    24841 tgcacttgta gttggtattg gagctggcat gtctgcagct gatggtttta cttatatcgg
    24901 gccgcgtttt gagacggcat tcccagattt tattgctaag tatcagtttt tggatatgct
    24961 gcaagctagc ctttttgatt ttgaagattg gcaagaatat tgggcttttc aaagtcgctt
    25021 tgtcgctttg aattatcttg atcagcccgt aggccagtct tatcttgatt taaaagagat
    25081 tttggaaacc aaagactatc atattattac tactaatgct gataatgctt tttgggtggc
    25141 tggttatgat cctcataaca tttttcacat tcaaggagaa tatggtttgt ggcaatgtag
    25201 ccagcactgc catcagcaaa cttataagga cgatacggtc atccgtcaaa tgatcgcaga
    25261 gcaaaaaaac atgaaagtcc caggtcaact gattcctcat tgccctgaat gtgaggcgcc
    25321 ttttgaaatc aataagcgta atgaagaaaa aggaatggtt gaagatgctg actttcatgc
    25381 ccaaaaagca cgttatgagg cttttttatc agaacataaa gagggtaaag tgctttatct
    25441 agaaattggt gtgggacata cgacgcctca gtttatcaaa cacccctttt ggaaacgtgt
    25501 ctcagaaaac cctaatgcct tattcgttac cttgaatcac aaacattacc gcatccctct
    25561 gtcaataagg cgacaaagcc tagaactgac agaacacatt gcacaattga ttagcgccac
    25621 aaaaaccatt taccaaaaat cgtaaccaaa gccaatagac ggttaattaa gagatataga
    25681 aggagactaa catgtacctt attgaaccga ttcgtaacgg taaacgtatc accgatggag
    25741 ctgttgctct agccatgcaa gtttatgttc aagaaaatct atttttagat gatgatattt
    25801 tatttcccta ctattgtgat cccaaagttg aaattggaaa attccagaat gcagttgtag
    25861 aaactaatca agagtattta aaagagcatc atatccctgt tgttcgccga gatactggcg
    25921 gtggtgccgt ttatgtagat tctggtgctg ttaatatttg ctacttgatt aatgataatg
    25981 gtgtttttgg tgattttaaa agaacctatc agcccgctat tgaagccctt catcatttgg
    26041 gagcaacagg ggttgaaatg tctggacgga atgacttggt tattgatggg aaaaaggtat
    26101 ctggcgctgc gatgactatt gctaatggcc gtgtttatgg ggggtattcc cttttgctag
    26161 atgtggactt tgaagccatg gaaaaagcat taaaacctaa tcgcaaaaaa attgaatcaa
    26221 aaggcatcag gtcagttcgt agtcgcgttg gaaacatcag agaacattta gcaccacaat
    26281 accaaggtat tacgattgaa gagttcaaag atttaatgat ttgccaattg ttacagattg
    26341 agacgattag ccaagctaag cgttatgatt taacggaaaa agactggcaa caaattgatg
    26401 ctttaacaga gcgtaaatat cacaattggg aatggaatta tggcaacgcg cctcaatacc
    26461 gttaccatag agatggccgt tttaccggtg gaacagtaga tattcattta gatattaaaa
    26521 aaggctatat tgcagcttgt cgcatttacg gagatttttt tggcaaggca gacattgcag
    26581 aacttgaagg tcacttgata ggaacacgaa tggaaaaaga ggatgtctta gctaccctca
    26641 atgcaattga tttagcccct tatttaggtg cgattacagc agaagaatta ggagatttga
    26701 tattttcttg ataaaaaaga tacctcagac cggtaaaacg cgattaaaaa acgaataata
    26761 attgttttaa ttcaaataaa tgtacgtatt atatgaattg tgatataatg acgtcattac
    26821 gtaaaattga ggagtcatca tgaaatcaga tatcgaaatt gcccaaagtg tcgccctaca
    26881 gccaatcact gacattgtta aaaaggttgg aatagacggc gatgacattg agctttatgg
    26941 caaatataag gctaaattgt cttttgagaa aatgaaagct gtcgaagcta atgagcctgg
    27001 aaaattaatc ttggtaactg ctattaaccc tactccagcg ggagaaggaa aatcaaccat
    27061 gtctattgga ctggcagatg ccttaaatca aatgggaaaa aaaaccatgc ttgccttacg
    27121 tgaaccctcc cttggtcctg ttatggggat taaaggcggg gcagcaggtg gtggttatgc
    27181 ccaagtattg cctatggaag acattaatct tcactttact ggtgacatgc atgccattac
    27241 aaccgctaat aatgcattat ctgctttgat tgacaatcat ttgcagcaag gaaacgattt
    27301 aggaattgat cctcgccgca ttatttggaa gcgcgtgttg gaccttaatg atcgtgctct
    27361 tcgtcaggta attgttggct taggtagtcc agtgaatggt gtgccacgcg aagatgggtt
    27421 tgatatcaca gtagcttctg aaatcatggc aattttatgt ttggcaactg acttgaaaga
    27481 tctaaagaaa cgtcttgctg atatcgtcgt ggcttatacc tatgatcgta agcctgtcta
    27541 tgtgcgtgac ttgaaggttg aaggagcatt gacattaatt ctaaaagatg ctatcaagcc
    27601 aaacttggtg cagactattt atggaacacc agctcttatt catggggggc catttgctaa
    27661 tattgctcat ggttgtaatt ctgtccttgc tacctcaaca gctttgcgat tagcagatta
    27721 cactgttacc gaagcaggat tcggggccga cctaggagct gaaaaattcc taaatatcaa
    27781 agtacctaat cttcctaaag caccagatgc tatcgtcatt gttgcaacct tgcgcgccct
    27841 taaaatgcat ggaggtgtcg ctaaatcaga tttagccgct gaaaattgtg aggctgttcg
    27901 cttaggattt gccaacttaa aacgtcacgt ggaaaacatg cgccaattca aagttccagt
    27961 tgtggtggct atcaatgaat ttgtagcaga taccgaggct gaaattgcta ccttaaaagc
    28021 gctttgtgaa gagattaagg ttccagtaga attagccagt gtttgggcaa atggagctga
    28081 gggaggctta gcattagcta aaacagtggt tcgtgtgatt gatcaagaag ctgctgacta
    28141 caaacgtctc tattcagatg aggatacttt ggaagaaaaa gtgatcaata tcgttaccca
    28201 gatttatggt ggcaaagctg ttcaatttgg ccccaaggcc aaaacacaat tgaagcagtt
    28261 cgcagaattc ggttgggata aattgcctgt ttgtatggct aagacccaat acagtttttc
    28321 agataaccca tccttgcttg gagcgccaac cgattttgat attaccattc gtgaatttgt
    28381 tcctaaaaca ggggcaggtt ttattgttgg tttaacaggt gatgtgatga ccatgcctgg
    28441 tttgcctaaa gttccagctg ccatggcaat ggacgtagca gaaaatggca cagccctcgg
    28501 tctcttttag gaaaaattgc tcgaataatt cgagcaagcg ctcctttctt cccgctttac
    28561 tgtgatataa taaggtaaat gagattttgg agggatgatt atcaaaaaga aagcaaaagt
    28621 aaaatatttg ctccataaag ggaaacatgg atttttaaga ggaattttta gtagaacaac
    28681 aatcattgta ttattaatta ttttgcaatt agttttctta tttcaatctt atgcctggat
    28741 ggagcagtac cgtgtttgga taacgattct tgaaagtgtc tttgctatta ctattgtttt
    28801 atatttagtt aatagtgata tggatgctat ttcaagaatg acgtggttaa ttttgattat
    28861 gattgctcca ttactagggt cactgttttt aatttataca aaattggatt ggggttacag
    28921 agggctaaaa caaagaataa atcatcttgt agatctgtct gcaccttacc ttagcgatga
    28981 tgacgctata ttagaggtat taaaggatag cacatcaacc acatatcatt tagtacagta
    29041 cttagaaaga agtcgtggca actttccgat ttataataat acaagggtaa cttacttccc
    29101 aacaggtgaa actttttttg atagtttaaa agaacagtta ttcttagcta aaaagtacat
    29161 ttttcttgaa ttttttatta ttgcagaagg ccaaatgtgg ggagaaatcc ttagtattct
    29221 agaaaaaaaa gtcagtgaag gtgtagaagt tagggtgttg tttgatggca tgaacgaact
    29281 atcaacgcta tcatcagatt acgccaagag attagaacaa atagggatta aagctaaatc
    29341 atttttaccg atttcaccct ttatctctac ctattacaat tatcgagatc accgaaaaat
    29401 tgtcgttatt gatggggagg tatcattcac tggaggtatt aatctagcag atgagtacat
    29461 taatgaagta gagcgttttg gccactggaa agatgctggt ttaatgcttg agggtgaagc
    29521 aacagacagc tttttaattt tgtttttaca aatgtggtct atcacagaaa aagaactgat
    29581 tattgatcct tatctttcag atcattcttt aaaacttcct tcagatggct atgttattcc
    29641 ctacggtgat tccccgcttg atactgataa aataggtaaa aatgtttata tagacatttt
    29701 aaatcatgct aaagagtacg tttatatcat gacaccttac cttattttag atagcgagat
    29761 ggaacacgct ttacgatttg catcagaacg tggagtagat atccgaatta ttatgccagg
    29821 agtgccagat aagggggtac catatgcctt agctaaaacc tattataaag ctttgatgac
    29881 ttctggagta aaaatttacg agtatcaacc agggttcgtt cattcaaagg tatttatctc
    29941 tgataataca aaagcagttg tcggaacaat taacttagac tatcgtagcc tttatcatca
    30001 ttttgaatgc gcgacttatt tatatcgtgt gtcagttatt gctgatattg tgaatgactt
    30061 taatgaagct caaaagcaat cactattgat gacatcagat catttgacgc aacgtccttg
    30121 gtatcaaaaa ttgataggat tattagtacg aacaattgcc cctctcttgt aattttcgta
    30181 aaatatgtta taatatctgt atgcgatgag tcgattgtga ctgcaaagtc acttttgcgc
    30241 aggggaggtc attaaggcgg gaagccgact ttgataatct gtgtgaacca ttttatcaca
    30301 atcttattta ttaagaatgc cccttggatt gagatattct caatcctttt tttaatttta
    30361 ttatcttagt taaaattcag aatgtatcag tgattactgt gtttcaaaat aagaaagtag
    30421 tttttcgggt atgagtgcta tgacttgaca aatgctaata acatttgcat aatgtaagta
    30481 gagatgaaaa cttatgaaaa gagatgatct tatgcaaatt attaagcgtg atggccacgt
    30541 tgctgatttt gatccagata aaatttatca agcaattatt aaagcagcaa ggacggtcta
    30601 tgttattgat gacacgtggc gacaaaactt aacacatgtc actaaaaaag tagttattga
    30661 tttagaagaa gcacatgtag aacgtcctac tatcaatatg gtccaatccc ttgtggagaa
    30721 tcgtttgatg gatgctggat atattaccat tgcagaacat tacatttctt atcgtcttca
    30781 gcgagattta gagcgcaatg gctatggtga taagattgtg gttcacttgc gttttgaaca
    30841 aataaaataa aaacgcttct aatggcattt tagtgtcttt gaggggataa ggtttaaata
    30901 cctaacagat aaaaatctgt taggtatttt tttgctacta ttaggtgtat tctatatcac
    30961 atagaactta agcattcaag ctttaattta actttctgtt tattttttgc tacattttgg
    31021 gaaactcccc tcctttctta gttgaggtga ataaactttt atttgataaa tcagattttt
    31081 aagtaatcta aaattatgtt tttttaattt caaaatcatg ctttcgtttg ttataaaaac
    31141 cgatcttcca tagttagatt ttttatccag gcaattgaag attggggcaa ctattcaatt
    31201 agagatttta taatacttat ttatccccat tttttatatt aatggtacga agaaaagtta
    31261 gttgctcttt ccacaagtat ttttgattag cgagtttaat ttgctttgta tttgttgatt
    31321 gatagcaata gagagatagc gcttttttcc agttattatt attctatcag atttatctaa
    31381 tgtaaagttt ctataagagt ctgatgtcgt gtaatcaatc actaaatgag taggggttag
    31441 ttgatagtga atatcagggc aattttgttt taaaaagaga gccaattgac gttcccgctg
    31501 ttttagataa cgcttaataa agcgaagatt tttttgaaac atcccatttt ctaaataaag
    31561 agctaatgct ttttgcatta gtaagttcgt gtctaaatca atcaatgatt tttgggttaa
    31621 aaaatgaggt tttaaacctg acggtaaaac tagagctccg atacggagtg caggaaaaac
    31681 actcattgaa aaagatttta gatagatgat tcggtgatga gtgtcataat aatgaattgg
    31741 tggctcttta agtttcacaa aatctcctaa ataatcatct tctaaaatat aaacctggta
    31801 tcgttgtgct agacgaacaa tagcttcctt ttccttagtg ttataagaaa gtcccagagg
    31861 atgtgaaaat cgtgaaatcg tgtaaaaaaa tttaatatcg ccagtttgaa ataaagattc
    31921 taagagttct aaatcaaggc cattaaagtg tctagagata gtttgatagg gtaatcctaa
    31981 ctgagcaaca atagcttcca tccgatgata agtaggcttt tcaaggagaa ttgttttgcc
    32041 cgcattagga aaaggcattt gtgataaaat ataaagcgct tgttgcgtcc cagaggtgat
    32101 taatagttgg tctttgttac tgtaaacact attttcagct aagtaaagaa gcaaagcttc
    32161 ccttagttct tctagtcctt cggttttgtg ataataatga aagaggtatt tgcctttagc
    32221 acttaaagcc tcatttaagc agagtcggaa atcttcataa gccatattat tataatcttc
    32281 aagacttaga ttaagaacat tatcgggtat gcttacgtta cccaaaacat aataaccact
    32341 tttaggaaca gcataaatta agtgacgata ttttaattct aaaagagccc gctgaacagt
    32401 atctttgcta caatgataaa ccttacttaa taccctaatt gaaggtagct tgtccccttt
    32461 ttttagtcgc tgtttctgga tatcttgttc gatattggaa atgattgttt gatattttgt
    32521 tgtcataaat tgtccccata cagttaagtg ttataactat tgtatcttat gcctcttttt
    32581 cttacaatag ttattataga aaagaggtaa tagctatgaa acggattatt gtggcaaatg
    32641 atctggttgg tgttggtaag gtagctttgt ctgctagtat tcctttaatg gcttcttgtt
    32701 tgttagagca agttttatta ccaacttgcc ttttatcaag ccatactggc ggaggacaga
    32761 accctgtgaa gcatactaca tcaagtatat tagacgtttt tttaacagat tgggacaaca
    32821 aaagaattaa gtttgacggc atctttatag gttattttac gacaacaaga gatgggcaaa
    32881 agctgctaga atggctttca agaaagcaac ttcccttaat tttagatcca attatggcag
    32941 ataatggaaa actttatcaa ggcttcagtc aaaaacatat agagattatg ataaaactta
    33001 ctcaaaaagc tgagcttgtt ttacctaata ttagtgaggc ttgtctatta acacaaacag
    33061 cttatttagc aaaaaattat gatgaagaag atattagaca ggtggctaga aaattagcta
    33121 agcttggacc taaacaggtt gtcattagcg gaatctcttt tgaggagggc agcattggtt
    33181 ttgcttacta tcagtcagat tcagatcaat taacattcca ttttgggaag caattccctt
    33241 accatttcta tggtacagga gatatagcat cagctattat aacagcagga ttctattatc
    33301 agctaccact aacacaaatt ctagatcttg ttgtttcatt tcttgaaaaa gtattgcaaa
    33361 atacccttac attaaaaaga gatttaatct taggtgttgc ttatgaatct catttaaatt
    33421 acttaactaa atcgtttaaa aagttgttgg aggaaaaaaa tgtcatctca aaaattagct
    33481 aattatattg aattgagtat gtatgccgct ttaattttta tttcagtaca agtgttgcgt
    33541 gtccctgtcg gtatgcagtt tattcatctt ggcaatgcat tagttgttat tgcagtctta
    33601 atctatggta gtaaaaaagg agctctagtt gctagtcttg gtttagggat ctttgatgtt
    33661 ttgaacggct atgcttcagt cgtttggata actatcttag aatccttggc tatttgttta
    33721 attttgcatt tggtatatga aagagctatg caatctagta aaaaaccaaa agccattata
    33781 acaataacag ttattgctgc attgtcaaaa ttaactatta accttataaa atacttactg
    33841 ttagcttata taggtactca gctaccactt tcggtatctt tttgggtagc tcttggaaaa
    33901 attggtggta gtttcggaac atcttttgtg actttagttg ctgttcctct tttgtatcct
    33961 gttatcaaaa acttaaaaga aaaggttaca atcggacaag caaaaagagg tttttgatac
    34021 aagtacctta tcgataaaaa agcaaggtac acttttagtc aaatattgac aaaaggttac
    34081 aattttgcca taatgaaata actataaagc cgttttgacg gcttttttga tgacagttaa
    34141 ggaagaaacg atgagtattt tagaagttaa gcagttgagt cacggttttg gggatcgggc
    34201 tatttttgaa aatgtgtcat ttcgtctctt aaaaggcgaa catattggac tagttggggc
    34261 aaatggtgaa ggaaaatcaa cctttatgag tatagtcaca ggacatttac agcctgatga
    34321 aggaaaagta gagtggtcga agtatgtcac tgcaggttac ctggatcaac atacagtgtt
    34381 ggaatcagga caaaccgttc gtgatgtctt gcgaactgct tttgatgagt tatttaagac
    34441 cgagaatcgt attaatgaga tttacgcgtc aatggcagat gataaagctg atattgctgt
    34501 tttgatggaa gaagtaggtg agcttcaaga tcgtttagaa agtcgtgatt tctatacttt
    34561 ggatgctaag attgatgaag tagcgcgtgc gcttggtgtt atggattttg gaatggagtc
    34621 agatgttaca tccttatcag gtgggcaacg aacaaaggtt ttattagcca aattactatt
    34681 agaaaaacct gatattctgc tattagatga accaactaac catttggatg ctaagcatat
    34741 tgaatggtta aaacgctatt tacaacatta tgaaaatgct tttgtgttga tttcgcatga
    34801 tatttctttc ttaaatgatg tgattaatat tgtttatcat gttgaaaatc aaagtttagt
    34861 tcgctatact ggggattatt accaatttca agctgtttat gagatgaaac aatctcaact
    34921 tgaagcagcc tatgaacgtc aacaaaaaga gattgctaac ttgcaggatt ttgtcaaccg
    34981 aaataaggct cgggtagcga cacgtaacat ggcaatgtct cgccaaaaaa aacttgataa
    35041 gatggatata attgaacttc aagctgagaa accaaaacca aattttgaat ttaagcaagc
    35101 tagaactccc agtcgattca tttttcaaac aaaaaatctt gtgattggtt atgattaccc
    35161 attgaccaaa gaacccttaa atataacgtt tgaaagaaac caaaaaattg ctattgttgg
    35221 ggccaacggt attggaaaat ctactttgct aaaaagttta ttaggtgtta ttgagccttt
    35281 agaaggtcat attgtcacag gggatttttt agaagttggc tactttgaac aagaagtgac
    35341 aggtgttaac cgacaaactc cgctagaagt agtttgggat gcttttcctg ccttaaatca
    35401 ggcagaagtt cgagcggcac tagctcgttg cggactaaca tcaaaacata tcgaaagtca
    35461 aattcaagta ctttcgggtg gtgaacaagc aaaagttcgt ttttgtttgt tgatgaatcg
    35521 tgaaaataac gtgcttattt tagacgaacc aacaaatcat cttgatattg atgctaaaaa
    35581 tgagctcaaa cgtgctttaa aagcatataa gggttctatt ttaatggttt gtcatgaacc
    35641 tgatttctac aatgggtggg taaccgatac ttgggatttt agtaagttaa cctaaactat
    35701 tccttaattt tttacacagg aattactaaa atcagtaaag atatagaata aatactgcta
    35761 gatatgtgat ggtttaggta actgatcacc aaccaaaaaa agatgtgact acatcttttt
    35821 tttatctaat ggaatggcgt aaagtcgttt aataatagct tattttttga tgatcagttg
    35881 ttcatgaaat tgttggtgat taacaagtca tttaagatac aaacgttatt actaaaaagt
    35941 gattcaaata gtttccctat ttttatgttt ttttaaattt attacgaata aatagataaa
    36001 gacagtgaag atacttagta agtacatctg ctaagattac gaatagatgg ggacaataaa
    36061 tgacgaattt aacgttttat gcaaaaatcg gtatttcaga agaagagcat gactcttttg
    36121 ttaaagaaca tcagcaaatt agcgttttac aaggtagtga ttgggcaaaa atcaaaaatc
    36181 aatggcagaa tgagcgaatt ggtatctata aagaggaaaa gcaggttgcc tctttatcac
    36241 ttttgattaa gctattgcca cttggaagaa gcattattta tattccaaga gggccagtca
    36301 tggattatct tgaccgtgat ttggtggcat ttaccatgaa aacactaaag gattatggta
    36361 aaactaaaaa ggccctcttt atcaaatatg atccagctat cttgttaaaa caatacgcac
    36421 tgggacagga agaagaagaa aaacctttag ctttagcagc tattaagaat ctccaagaag
    36481 ctggtgttca ttggactggt ttaacaatgg agattgcaga tagtatccaa cctcgtttcc
    36541 aagctaatat ttacactcaa gaaaaccttg agatgcaatt tcctaagcat accagacgtt
    36601 taataaaaga tgctaagcag cgtggtgtag aaacatatcg tgccagtcaa tcagaacttc
    36661 acaaattttc caagattgtc tccttaacag aaaaacgtaa aaatatttct ttgcgtaacg
    36721 aagcttactt tcaaaagttg atgactactt atggggataa ggcctactta catctagcaa
    36781 aagtgaatat tcctcaaaaa ctagatcaat accgccagca attaattctt attaaccaag
    36841 atattactcg cacccaagct catcaaaaga agcgtttaaa aaaattagaa gatcaaaaag
    36901 cttctttaga acgttatata actgaatttg aaggttttac agaccaatat cctgaggaag
    36961 ttgttgtagc aggtatatta tctatttctt atggaaatgt tatggaaatg ctttatgctg
    37021 ggatgaatga tgattttaag aagttttatc ctcagtatct gctgtatcct aaagtttttc
    37081 aggatgctta tcaagatggt attatttggg ctaacatggg aggagtagaa ggctcgcttg
    37141 atgatggact taccaaattt aaggccaact ttgctccgac aatagaagaa tttataggag
    37201 aatttaatct ccctgtcagc ccactttatc atattgctaa taccatgtac aaaatacgaa
    37261 aacagttaaa gaataaacat taaaagactc gccaaaatga gcgagtcttt taatgtttat
    37321 tctgttattc ccattcaact gttgcgggtg gtttacttgt gatgtcgtag acgatacggt
    37381 taacgtggtc aacttcattt acgatacgtg ttgagatttt tttcaagaca tcccaaggaa
    37441 gttgagcaaa gtcagctgtc ataccatcaa tagacgtaat agcacgaatg gcgatggtat
    37501 aatcataagt acgaccatct cccatgacgc ctacagaacg gacacctgtg ttaactgtaa
    37561 agtattgcca cacgtcacga tcaagtccag ccttagcaat ttcttcacga aggatagcgt
    37621 ctgattcgcg aacggtttca agtttttctt cagtaattgg tcccatgaca cggatagcaa
    37681 gtccaggacc tggaaatggt tggcgccaaa caatttcttc aggcattcca agagcgattc
    37741 caagcgctcg aacttcatct ttgaaaagag tgtttaaggg ctcaatcaat tcaaactgca
    37801 tgtcttcggg gagaccaccc acattgtgat gtgatttgat ggtttgagca gtttctgttc
    37861 ctgactcaat gatatcagta taaagtgttc cttgggcaag gaagtcaaca ccttttaatt
    37921 tgctggcttc atcatcaaaa acatagacaa attcattacc aataatttta cgttttttct
    37981 caggatcttc aacgtctgca agaaggtcta agaaacgttt tgaagcatcc acacggataa
    38041 tatttaggcc aaatttgccc ccaagcattc ccataacttg atcgccctcg tctttacgaa
    38101 gaagaccgtg atcaacgaaa atacaagtta attggtcacc aatagctttt tgaagtagaa
    38161 caccaacaac tgaagaatca actccaccag aaagacctag aagaacttta cgatcgccta
    38221 cagtttcacg aattttagca atttccatgt caataaaatt atccattgac caatcaccac
    38281 gcgcgccaca aattgatata gcaaagtttt taagaatgtc atttccataa acagagtgtc
    38341 ttacttctgg gtggaactga ataccgtaaa ggtttttctc agtattttca atagctgcat
    38401 agggacagtc atttgagtct ccaacaaggt ggaaaccttc tggaatttca gtaacagcat
    38461 caccatggct catcaaaacg agttgttctt gaggtgtgcc tgaaaataat tttgacgttt
    38521 cacgaagatg aagggttgac tgaccgtatt cacgattacc agcttgtcca gcaggaacaa
    38581 ctttaccacc taatttatgg gtgattaatt gcataccgta acagatacca agaatcggaa
    38641 tccctagttc aaagatttca gggtcaatgc caaaggcgtt atcagcgtaa acagagttag
    38701 gccctcctga taaaacgata cctatgggat tgatctcacg aagttcttga gcggtgattt
    38761 tatggctttt tagttcggag aaaacaccaa actctcgaat acgtctagca ataagctgat
    38821 tgtactggct accataatca agaacgataa ttttttgaac atcattcaaa attgaaattt
    38881 cagtcattat aatcctttca ttctatacca accgtcaggt tgatagttgt caacttattg
    38941 tagcatattt tcatcgaaaa gacattacaa tttctctagc tcgttggaaa aaaacgtaat
    39001 cgttatgtta caatagaggc tatgaaaggg aattaagaca acagggaggg cctatgctaa
    39061 gaaaaaagag aattttgggt ttatttcgac ctgttgaatt aattttccta ggattattgt
    39121 tgagtttagt tgtttcgtac cttgcgtgga ccaatagttt tgcaacactt cacaatatat
    39181 tagcaactgt cggaatagtg gaacgaagca aagatcaaca gcctcgctat cacattggac
    39241 aagctattca agtacaaaaa agtggtccat atcatcaatg gattggaact attaataaac
    39301 aagtagaaga tatagccgaa aattaccgag tgagttatca ttatgaagtg gtatttccaa
    39361 taggaaaagt cactgtttct ttgccagaac ataacctgaa aaagcctgat aaaccgaggt
    39421 ttaaaaaagg agatatcgtt aaattatctt cattaactaa aaagccacat ataaaagtgt
    39481 atcaaggtca attagcgact attaaacaag ttaaaaaacg ctatgactat tcgttaggag
    39541 gatatcagta cgatattaac ctgaaagata atctaagatt agatggaatt tcagagcaag
    39601 attttgttaa accttattat attaggttca ataaaggaaa ttcccctgag caaaacaatc
    39661 gtcttttgcg aaaagctttc gcctatgcaa agcagcatcc aaatagcgtt atatcttttc
    39721 caaaggggca atttcacatt ggctctttgc cttcacaaaa agattatttt gagcttccat
    39781 ctgatacagc tattattggt catcagacag agttcattat tcacggtaaa atgttgtggt
    39841 ttggattccc tacaggacca aaggctgaac aaggtgttcg taatctcgtg ttgactggag
    39901 tgcatttcaa agcaaatgat ttgaaaaaag gagaccactt tatgattatg gctgatcatg
    39961 gtactgattg gcatatttac gataacaaat ttactatggt tcataagcgt aatagtcata
    40021 tttttgattt aggatctcta caaaattcat tgtttgagaa aaaccaattt attggctatg
    40081 cgccagaatt agtacaagac caacagctgc tatcaaaggc tcaagggcat gatttttttt
    40141 cagaagtcat tcagtttgat gctgctgttc atcattttgc atgggatgga ggtctactta
    40201 gtaatattgc tccaaactat gaagcattta accaaactcg acatctatgt cacaatatta
    40261 ctgtaagcca aaatcaattt ttaccttata tagatccgac tggttgcctg agagcctata
    40321 gtggttctat tggtcagcat tcctcaaaag taggagttat tagggtttta aataatgttt
    40381 ttacctcatc cattgttact aaagcgaagc tcactagttg gtttatggaa cctattcatt
    40441 ttccaccaaa ttcaccagtt attgtcgcag gtaatatcat taattgatgc caaatacctc
    40501 aatatttaca attcaatttt catcaaaaat atgataaaat agatgaataa ccgacttgag
    40561 gagtgtggca tgttaccagc ttatataaaa attcatgatg caattaaaaa agacattgat
    40621 ctgggcatct ggccaattgg tagtcgctta ccaagtgaac gacatttagc ggaacatttc
    40681 accgttagtc gaatgactct acggcaggct attacattac tagtagaaga agggattctt
    40741 gaaaggcgga taggaagtgg tacttatgtt gccagtcatc gtgttcaaga aaaaatgcga
    40801 ggaacaacaa gtttcacaga aattatacgc tcccaaggac gacaaccctc ctctaaatta
    40861 ttatcctatc aaaagcaatt agctagtgat accgaagtta aagaattgaa cttagacaaa
    40921 acagacttgg tcattcgaat ggaacgtatc cgctatgcag acagtgtccc tttggtgtac
    40981 gaaattgctt caatcccaga aaaatttata aaaacggtta aacgagctga tattacagaa
    41041 cacttttttc actcattgat agcaaatggt tacgagattg gtaaaagtaa acagacaatc
    41101 tacgctaagc tagcaagtga gcgtgtagcc tcctacttgg aagttgctaa aggacatgcc
    41161 attttggctc taactcaggt gtcttacttt acagacggca aaccttttga gtatgtccgc
    41221 agtcagtata tcggtgaccg ttttgaattt tacttagaaa ataattagta aagaagtcat
    41281 ttatgacttc cttttttaca cgaacggcac aaggcaatta atttgctact gttaaaaaca
    41341 atcatagtat gataaaatga acactatgga aattgaaaaa acaaacagga tgaatgccct
    41401 ttttgaattt tatgcagctt tgctaacaga taaacaaatg aattatattg aactgtatta
    41461 tgccgatgat tatagcttag ctgagattgc tgatgaattt ggtgtcagtc gtcaggctgt
    41521 ctatgataat attaagcgta cggaaaaaat tttagagact tatgagatga aacttcatat
    41581 gtattcggat tatgttgttc gaagtgaaat ctttgacgac atgattgctc actaccctca
    41641 tgatgagtat ttgcaagaaa aaatttccat tttaaccagt attgacaata gagagtaaga
    41701 ggagttttga ctatggcttt tgaaagctta acccaacgtt tgcaagatgt gtttaaacac
    41761 attcgcggta aaaagaaatt atcagaatca gatgttcaag aagtgacaaa agagattcgt
    41821 ctagctcttt tagaagccga tgtcgcttta ccagttgtta aaacctttat taagcgcgta
    41881 cgtgagcgcg ctattggcca tgagattatt gatactcttg atccaacaaa acaaattctt
    41941 aagattgtta atgaagaatt aacgagtatt ttaggctcag aaactgcaga gattgataaa
    42001 tctccaaaaa ttccaactat tatcatgatg gtcggtttgc aaggggctgg taaaacaact
    42061 tttgcaggaa aactcgctaa taaattaatt aaagaagaag atgcgcgacc actgatgatt
    42121 gctgccgata tttaccgtcc agcggccatt gatcagttaa aaacactggg gcaacaaatc
    42181 aatgtacctg tttttgatat ggggacagac cactcagcag tcgatattgt cagaaaaggt
    42241 ttggaacaag ctcgtgaaaa ccacaatgac tatgtcttga ttgatactgc gggtcgcttg
    42301 caaattgatg aaaaactgat ggaagagctg cgcgatgtca aggctttagc acaaccaaat
    42361 gaaattcttt tggttgtaga tagcatgatt ggtcaggaag ctgccaatgt agcctacgaa
    42421 tttaatcatc agttgagcat cacaggggtt gtgttaacaa agattgatgg tgatacccgt
    42481 ggaggtgcag cgctatctgt ccgtgaaatc actggaaaac caattaaatt tacaggtact
    42541 ggtgaaagaa tcacagatat tgaaacattt catccagacc gcatgtcgag tcgtatattg
    42601 ggaatgggtg acttactcac tcttattgaa aaagctagcc aggaatatga tgagaaaaaa
    42661 tccttagagt tagctgaaaa aatgcgtgaa aacacctttg atttcaatga ttttattgaa
    42721 cagttagatc aagtgcaaaa tatggggcct atggaagacc tcttgaaaat gattccagga
    42781 atggctggta acccagcttt ggccaatatc aaagttgacg aaaaccaaat tgctcgcaaa
    42841 cgtgctattg tctcttcaat gacacccgct gaacgtgaaa atcctgactt actaaacccg
    42901 agtcgtcgcc gtcgtattgc agctggttcc gggaacagct ttgtagaagt taataaattt
    42961 atcaaagact ttaatcaagc caaaagcatg atgcaagggg ttatgtcggg tgatatgtct
    43021 aaaatgatga aagatatggg tattaatccc aataatcttc ctaaaaacat gcctgctggt
    43081 atgcctgata tgtcttcctt agaagggatg atgggacaag gtggtatgcc tgatttatct
    43141 agccttggtg gtgatatgga tatgagtcaa ctgtttggtg gtgggttcaa ggggaaaatt
    43201 ggacaatttg cgatgaaaca ggccatgaaa cgtcaagcta ataaactaaa aaaagcaaag
    43261 aaaaaacgaa aataaaagag acgaaaattt tcgtctcttt ttgatgtgaa attcatttat
    43321 cttgtataca agattattaa aattacggaa gaccgcgtta catgcatgat gagttcattt
    43381 aaaatttgaa ataacctaat caatctaact taaatttcta agggcctaaa attagcgata
    43441 attttgccaa taatgcgagg ttcttcgcta tagggagcaa acttatcaga atatttttta
    43501 tttaaggaca ctagacgtaa tccctcatct tcacgaaata cctttttgat atatgtttgc
    43561 ccatcccatt cgactgcata aattgctcca tcgtaatcaa aactattttg ttttataaga
    43621 acaacttcac catttaaata agttggctcc atagaatctc caaaaaccca agacgcaaaa
    43681 tcgtattcta attgttcatc gtaaaagaca acatcaaagt taccatcacc aaaataggag
    43741 taaccagtac cagcagataa actttcatag acccgataag catataattg tgatggttta
    43801 tctatgagat ctttagattt tttgtctatt tgatgattta acaatcgctc tgaatagcca
    43861 attacttttt ctttattaga tattgtcagc tggttataag gcgttagcaa tttatagttt
    43921 gggtcgaaat aatcagatgt cacattgaat agatgcaata aggcatttaa atgtttttca
    43981 tttggtatat tcttaccttt ttcccaatta gatattgtca ttttattgac atgcaacaat
    44041 cctcccaatt ctgattgagt tattcccttt gataatcgtg ctgtttttag ttgatgtcca
    44101 gaaaacattt ggtagctcct ttagtaaagt tataacttta ctaatagtat caaaaaaata
    44161 aaacgaaagc aagtgtaaca tttcctacaa ttaattcatg tgatagcaat actgtcaaaa
    44221 agaggaaaca cctaaaacat agcgactaga ttcgtgtact agcaggtcta tatctgataa
    44281 agagttaatt actttaaaga taaaattatc atttagttct gagctaaaca aattctgtgc
    44341 ctgaagttac taaaataatg atagtaaatt attactgaat ctaaaagaag tgacgttagt
    44401 atctgtaaaa aagagatctg tctcgtaaca tctttccgaa aaactgtaat tttcttgaaa
    44461 aatatttata ggtgtgatat actgctcttg taaagaatga atggcataaa atacatgaga
    44521 caatttgcga aaattcattt ttgaaaaaat tgttattgtt aaggaattat gatgatatga
    44581 gacgcgaatt attactagaa aaaattgaaa cctataaggc catcatgcct tggtatgttt
    44641 tagattatta ccaatccaag ttagctgttc catacagctt taccacctta tatgagtatt
    44701 taaaagaata caaacgcttt tttgattggc tgatggatgc tgatttaacg caggcgccaa
    44761 agattgctga tattgacttg agcacgcttg agcaccttac caagaaggat ttagaggcct
    44821 ttgtgcttta tttgcgggaa cgaccttctc tcaacaccta ttccaccaaa gagggtcttt
    44881 ctcaaaccac tattaatcgg accttgtctg ccttatcaag cctttataag tacttgactg
    44941 aagaggttga aaatgaccaa ggagagcctt atttttatcg gaatgttatg aaaaaagtgt
    45001 caacaaaaaa gaaaaaagaa accctggctt ccagagcgga aaatattaag cagaaactgt
    45061 ttttaggtga tgaaactcta gctttcttgg attatgtgga taaggaatat gagcaaaaat
    45121 tgtctaatcg tgccaaatct tctttccgta aaaataagga gagggatttg gctattattt
    45181 ctctactact tgcttctggt gttcgtttgt ctgaagcagt gaatcttgat ttaaaagatg
    45241 tcaatctaaa tatgatgatt atcgaagtta ttcgcaaagg cggaaaacgt gattcagtca
    45301 atgtagcagg ttttgcgaaa ggttatttgg agtcttattt agctgttcgt cagagacgtt
    45361 acaaggctga aaaacaggat cttgctttct ttttaacaga ataccgtggc gttccaaatc
    45421 gaatggatgc ttctagtata gaaaagatgg ttggcaagta ctctgaggat tttaaaattc
    45481 gtgtgactcc tcacaaattg cgtcatacgc tagcgacaag actatatgat gctactaaat
    45541 ctcaggtgtt agttagtcat caattaggcc attcctctac tcaagtcacg gatctttata
    45601 cccatattgt caatgatgag caaaaaaatg ctttagataa cctttaatgt tacataattg
    45661 tttttatgta acattaaagg taaaaatagc ttcaaaatta actttaatag atggctacta
    45721 ttaaccgtga cagtttggtg tcagaccgtt ttccaaacta ctcaagccac ttagaaaaag
    45781 gaatatcact gctaactttg tcccttcttt gaatgacttt tttgcgatgt ttatagatta
    45841 aatctagtag ggttctcatc aaaaagatga gataagccta tttttagtat gtcagtactt
    45901 ttatttagta tgataatatg ttatcttgta aagtagcttt taggattatt cttgttaaaa
    45961 tacttaatgt tattactgat aacttagagt aatataaagc taaaattgaa ggaatattag
    46021 agaatcatga agacagcttc tttaacatca attggttgaa tacaaggatc agataacatt
    46081 atcgctagat agtctgaaga atcaaaaaca aagtttgtta cataaataaa ttcttgtcaa
    46141 aacttgtatt ttctatttga actgatacga ttgacaaagg ctaaactaaa atagcttgac
    46201 ttttttagaa tctttgtatt ttttgtcgga ccccctccta ttttttcctt gaattgatct
    46261 atttaacctt ttagaacaag gtttatcgca tactattttt agacaatttg ttataataaa
    46321 aagaaacgac ttgaggagat aaaagatgcc aaagagaata agaaaagctc taggagtagt
    46381 tgggaaactg atgtcaattg ttcctgacac tactgaaatt attggaaaaa cgattgataa
    46441 cagtcgacca attatcgaaa aacgtatgga acaaaaacat gaaaaagaga tgcaactacg
    46501 cacgatagat gatgtgatta atcttcctgt tgatcaggca caagctcatt tggaacaact
    46561 tggctttgta gtagccacta tacctgctaa gcctcataaa aaatggcttc atagtaatct
    46621 caatgaagtg gttgctatgt ctccaaaatc tggtaaatat aagataggaa gcctgatcaa
    46681 actctactac attactgttg atgttgtgga aaaaagtcaa gacttattag accaagaaaa
    46741 cttgcggact gtggaacgca atcaaaaaat cgctgatact tttgagtctg tcaaacacat
    46801 tcgatttcct tttaaaaaat ggcgttgata aaaaacagag ttgcctttag atagatcagc
    46861 ctgttttggt actaagttat gttatgattc aataaaatta aagataagga gaagaaatgc
    46921 cttactacac tatttcaaaa gtctttcctt cagataaaac gacaatgact agtgtaaaga
    46981 acctgcttca tcaagaaggt attcgtttgg atgctcattt agattatact tgtgccatca
    47041 tgaatgcgca aaatgatgtg attgctaccg gttcttactt tggaaatagc ttgcgctgtc
    47101 tttgcgtatc cagtgcctat caaggtgaag gacttcttaa taggattgtg agtcatctca
    47161 ttgatgaaga atatgccctt ggcaactatc atctttttgt ttatacgaag acctcttctg
    47221 ctgctttttt caaagatctt ggttttactg aaattgtcca tatcgacaat cacatcagtt
    47281 tcttggaaaa taaaaaaact ggttttcaag attatctgat gacacttaat aagcctgagc
    47341 aaacacctgg taaagtcgct gctattgtta tcaacgctaa cccctttacc ttagggcatc
    47401 aatttttagt agagaaagct gcaagagaaa atgattgggt tcatctgttt atggtcagtg
    47461 aagaccgcag tctaattcct ttttcggtga gaaagaggtt gattcaagaa ggtctagctc
    47521 atcttgataa tgtcatatac catgaaacag gtccttattt gattagccaa gcgactttcc
    47581 cagcctattt ccaaaaagaa gacaatgacg tgattaagag ccaagccttg ctggataccg
    47641 ctatttttct aaagattgct caaaccttac agattacaaa aagatacgtt ggagaagagc
    47701 caaccagccg agtaactgct atttacaatg aaatcatggc agagcagttg cagcaagctg
    47761 gtatcctcct agatattttg ccaaggaaag ctatcaatca gcagcaagat cctatcagtg
    47821 cctcaacggc taggcaggca ttgaaagata atgattggga
//
LOCUS       DAXMQE010000013        45227 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.013, whole genome shotgun sequence.
ACCESSION   DAXMQE010000013 DAXMQE010000000
VERSION     DAXMQE010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 45227)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45227)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45227
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.013"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            <1..207
                     /locus_tag="ACF4ZO_000819"
     CDS             <1..207
                     /locus_tag="ACF4ZO_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486381.1"
                     /translation="ASDLVEKVAQAQNNKTDAQNNPKKLVQNTNLPKTGAGDGLNPFL
                     HEMILGISGLALAITGYFRKKHAK"
     gene            468..869
                     /locus_tag="ACF4ZO_000820"
     CDS             468..869
                     /locus_tag="ACF4ZO_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001933620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase subunit sigma-70"
                     /protein_id="HFD5486382.1"
                     /translation="MNVEEKNLIRELREKALGYKRISGELGISVNTIKSFCRNHKLTR
                     EHIVRTIYCKECGKELIQKEHTKKKIFCSDACKRKWWNGHRKSLSKTTMEEYICLNCH
                     KKFKAYVAEHRKYCCHSCYIKARFQGSDDHE"
     gene            889..954
                     /locus_tag="ACF4ZO_000821"
     CDS             889..954
                     /locus_tag="ACF4ZO_000821"
                     /inference="COORDINATES: protein motif:HMM:NF042617.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486383.1"
                     /translation="MYQLSISIAERMYENHLLNKG"
     gene            1014..1502
                     /locus_tag="ACF4ZO_000822"
     CDS             1014..1502
                     /locus_tag="ACF4ZO_000822"
                     /inference="COORDINATES: protein motif:HMM:NF019149.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase zinc beta ribbon domain-containing
                     protein"
                     /protein_id="HFD5486384.1"
                     /translation="MYIGDRRMQKTSVKGPIKQNKVKNKGELPQYYVENNHKAIVDKE
                     TFDAVQAVLDRTEKGKGSTTLFCSKLVCGDCGHYFGSKVWHSTSKYRRVIYQCNEKYK
                     GEKKCTTPHVTENEIKDWFVSVINKVISNKDEIIQNLEMLLDVGKSSDLERIFRDTQS
                     AK"
     gene            1791..2216
                     /locus_tag="ACF4ZO_000823"
     CDS             1791..2216
                     /locus_tag="ACF4ZO_000823"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486385.1"
                     /translation="MDGPIAEAVIHVQKITSEQIEFHFGWITSVSGIGGNEYFGGMTY
                     LVATIIYIILNDSSLKNRMIRISLDMQSEAREVAINRKIDVYHKFFKTPKNISDVSEF
                     SFHRVATFSPENRKHDLEYFKGIIEEKEKSILSVLDSYR"
     gene            2232..2828
                     /locus_tag="ACF4ZO_000824"
                     /pseudo
     CDS             2232..2828
                     /locus_tag="ACF4ZO_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989173.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0030420 - establishment of competence for
                     transformation [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ComEC/Rec2 family competence protein"
     gene            2909..3949
                     /gene="holA"
                     /locus_tag="ACF4ZO_000825"
     CDS             2909..3949
                     /gene="holA"
                     /locus_tag="ACF4ZO_000825"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HFD5486386.1"
                     /translation="MIAIEKIEKLNKQNLGLITLVTGEDIGQYSQLKSRLMTQIAFDK
                     DDLAYSYFDMSEAAYQDAEMDLVSLPFFAEQKVVIFDHLLDITTNKKSFLKEKDLKTF
                     EAYLENPLETTRLIIFAPGKLDSKRRLVKLLKRDALVLEANPLKEAELRTYFQKYSHQ
                     LGLGFESGAFDQLLLKSNDDFSQIMKNMAFLKAYKKTGNISLTDIEQAIPKSLQDNIF
                     DLTRLVLGGKIDAARDLIHDLRLSGEDDIKLIAIMLGQFRLFLQLTILARDVKNEQQL
                     VISLSDILGRRVNPYQVKYALKDSRTLSLAFLTGAVKTLIETDYQIKTGLYEKSYLVD
                     IALLKIMTHSQK"
     gene            4046..4651
                     /gene="sodA"
                     /locus_tag="ACF4ZO_000826"
     CDS             4046..4651
                     /gene="sodA"
                     /locus_tag="ACF4ZO_000826"
                     /EC_number="1.15.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004784 - superoxide dismutase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase SodA"
                     /protein_id="HFD5486387.1"
                     /translation="MAIILPELPYAYDALEPQFDAETMTLHHDKHHATYVANANAALE
                     KHPEIGENLEELLADVTKIPEDIRQALINNGGGHLNHALFWELLSPEKQDITPDVAQA
                     IDDAFGSFDAFKEQFTAAATGRFGSGWAWLVVNKEGQLEITSTANQDTPISEGKKPIL
                     ALDVWEHAYYLNYRNVRPNYIKAFFEIINWKKVSELYQAAK"
     gene            4818..4964
                     /locus_tag="ACF4ZO_000827"
     CDS             4818..4964
                     /locus_tag="ACF4ZO_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486388.1"
                     /translation="MLREKKTTIVGIILGMMIVTLLVGCLTGKKKGFPPKAGKRQQTA
                     EKQD"
     gene            5020..5259
                     /locus_tag="ACF4ZO_000828"
     CDS             5020..5259
                     /locus_tag="ACF4ZO_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486389.1"
                     /translation="MDTDLVEMDALGLYYDDNHLSLVNTVKAYLKEFGIGESQIAFSY
                     KDLNSVRTVAMNDHQPMIAGSTYKLPLNMLVVNYP"
     gene            5256..5846
                     /locus_tag="ACF4ZO_000829"
     CDS             5256..5846
                     /locus_tag="ACF4ZO_000829"
                     /inference="COORDINATES: protein motif:HMM:NF024748.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008800 - beta-lactamase activity
                     [Evidence IEA];
                     GO_process: GO:0030655 - beta-lactam antibiotic catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HFD5486390.1"
                     /translation="MTERFDITETDYEYDQEHHAYVAQFNGAMSILDMQEYSLVYSEN
                     TPAYALAERLGGMNKAYQLFDRYGKVSGAITTIDRNGNKITTTYYLQVLDYLWQHQDK
                     YKDILYYIGESFPDLYYKTYLPHVKVYQKPGYVREALNVGAIVCEESPYLIALYSSGL
                     GGATQASEEVNGLGYVQLVQLTYVINEWHRVNHNMI"
     gene            complement(5960..7180)
                     /locus_tag="ACF4ZO_000830"
     CDS             complement(5960..7180)
                     /locus_tag="ACF4ZO_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3114 domain-containing protein"
                     /protein_id="HFD5486391.1"
                     /translation="MKLLGKWLFFLMFLTFCVSFWQKDYQRIAFEKEHKLYQDLVAPF
                     YQNYPKLRELQLSEAIKLRHDLLDYVRKLDKDGWSYKAIQKGYLEQLAVRGNSYHFEQ
                     LYSRIRLIGSPDFQKLWQQEEMAQTPQEAQKRLQLLLTYLKMPDELTGQSKQTQQVLA
                     QLSPKLSPTDPFWDQLSALIQACYVNLEHIPYSRFNRKIHQLRYLISTQQMEWVRSHY
                     GNKGKTDADALAKYLATLEDDDYALYESSRYHNKVASILDSNGNHQAVYTDNIPQANY
                     KILIHFHSEFILSESGQFLVALDPDNLTRNSIVNGSSFNYGNQNDDLHRLLDIDPILL
                     FDPAFIEKATNSPDATFLVPDLEQQRDKHNPIYSRNGKSSKQLTRAAVKKFKKLLHHY
                     QETRGDNKTSKTQH"
     gene            complement(7187..8215)
                     /gene="queA"
                     /locus_tag="ACF4ZO_000831"
     CDS             complement(7187..8215)
                     /gene="queA"
                     /locus_tag="ACF4ZO_000831"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HFD5486392.1"
                     /translation="MNTNDFDFELPEELIAQTPLEKRDSSKLLIIDHRQKTMVDSHFD
                     HIIDQLNPGDALVMNNTRVLPARLYGEKPDTHGHVELLLLKNTQGDQWEVLAKPAKRL
                     KVGSQVNFGDGRLKATIIDELEHGGRIVEFSYDGIFLEVLESLGEMPLPPYIHEKLED
                     AERYQTVYAKENGSAAAPTAGLHFTTDLLKKIEAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHDMHSEFYSLSEEAAQTLRDVKQAGGRVVAVGTTSIRTLETIGSKFQGDIQADSG
                     WTNIFIKPGYQFKVVDAFSTNFHLPKSTLVMLVSAFAGRDFVLEAYRHAIDEKYRFFS
                     FGDAMFVN"
     gene            8417..9121
                     /gene="nagB"
                     /locus_tag="ACF4ZO_000832"
     CDS             8417..9121
                     /gene="nagB"
                     /locus_tag="ACF4ZO_000832"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004342 - glucosamine-6-phosphate
                     deaminase activity [Evidence IEA];
                     GO_process: GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HFD5486393.1"
                     /translation="MKIIRVQDQIEGGKIAFTLLKDSLAKGAKTLGLATGSSPISFYQ
                     EMVKSRLDFSDLTSINLDEYVGLSVESDQSYDYFMRQNLFNAKPFKKNYLPNGLATDV
                     EAEAKRYDQIIAEHPIDFQVLGIGRNGHIGFNEPGTSFEEETHVVDLQESTIEANSRF
                     FTSIDDVPKQAISMGIASIMKSKMIVLLAFGQEKADAIKGMVFGPITEDLPASILQKH
                     DHVIVIVDEAAASQLD"
     gene            9240..9956
                     /locus_tag="ACF4ZO_000833"
     CDS             9240..9956
                     /locus_tag="ACF4ZO_000833"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HFD5486394.1"
                     /translation="MRLDKLLEGTKVGSRSQVKKLIKAQGVWVDHMPARNGRQNVDPG
                     LQLIEVTGQRVTHPKHSYIILNKPSGVVSAKKDTNYLTVIDQLAEEDKSPDLYPVGRL
                     DRDTEGLVLLTDNGPLGFRMLHPSHHVSKTYLVTVNGLLAEDASDFFAAGICFPTGEQ
                     CQPAQLTILKADIDQSQASLTISEGKFHQVKKMFLTYGLKVTSLKRTHFAGLELGHLA
                     SGEYRYLTESERQLIKTYLD"
     gene            10252..11214
                     /locus_tag="ACF4ZO_000834"
     CDS             10252..11214
                     /locus_tag="ACF4ZO_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HFD5486395.1"
                     /translation="MTKILTALDGKNQLISLVTQPISTKPPFRCPACKSPVRLRQGTI
                     RRPHFAHVQLAHCQFQAENESEEHLTLKAKLYTSLVRTEAVCIEKYLPELQQIADLWV
                     NDKLALEIQCSPLPVERLKKRTKAYQEKGYPVRWLLGRKLWLNTHLTALQKQFLYFSS
                     SLGFHLWELDAAANLLRLKYLIHEDLFGKVSYLTKTISLDHNIMEMFRLPYQQEILYS
                     YQKKMTVNLSKRIQRALLARHPKWLRRQEKAYLSGYNLLMLTTDAFYPQWRPVQSSSG
                     FCQIKGNLRPYYESFKVYYKKEKDKKVQTLFSPKYYVKMDSNRK"
     gene            11227..13032
                     /gene="pepF"
                     /locus_tag="ACF4ZO_000835"
     CDS             11227..13032
                     /gene="pepF"
                     /locus_tag="ACF4ZO_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HFD5486396.1"
                     /translation="MTDNRSHLEEKYTWDLSTIFATDKDWEAEVSDLATEVEASKGFA
                     GHLLDSSANLLKVTKTYLELARRVEKVYVYAHMKNDQDTTVAKYQEYQAKASGLYAKF
                     SEVFSFYDPEVMMLHQEDYQAFLTETPELKVYNHFFDKLFQAREHVLSQAEEELLAGA
                     QEIFNGAEETFSILDNADIVFPIVRNDKGENVELTHGNFISLMESKDRSVRQAAYEAM
                     YSTYEQFQHTYAKTLQTNVKVQNYKARVHKYDSARQAAMAANFIPEAVYDTLLETVNK
                     HLPLLHRYLKLRQEVLGLDDLKMYDVYTPLSETDLAIGYDEALEKAEKVLAVFGKDYA
                     DRVHRAFTERWIDVHVNKGKRSGAYSGGSYDTNAFMLLNWQDTLDNLYTLVHETGHSL
                     HSTFTRETQPYVYGDYSIFLAEIASTTNENIMTEALLNEVQDEKERFAILNHYLDGFR
                     GTVFRQTQFAEFEHAIHQADQKGEVLTSEYLNQLYADLNEKYYGLSKKDNHFIQYEWA
                     RIPHFYYNYYVYQYATGFAAASYLADKIVHGTQDDIDHYLAYLKSGNSDYPLEVIAKA
                     GVDMAKGDYLEAAFKVFDERLTELEVLVSKGIHKS"
     gene            13408..14604
                     /locus_tag="ACF4ZO_000836"
     CDS             13408..14604
                     /locus_tag="ACF4ZO_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HFD5486397.1"
                     /translation="MEKTKRYIIATAGILLHLMLGSTYAWSVYRNPILQETGWDQAPV
                     AFAFSLAIFCLGLSAAFMGNLVEQYGPRLTGTVSAILYASGNMLTGLAIDRKEIWLLY
                     IGYGVIGGLGLGAGYITPISTIIKWFPDKRGMATGFAIMGFGFASLLTSPIAQWLIET
                     EGLVATFYLLGLIYLIVMLFASQLIIKPTAAEIAILDKKRLQNNSYLIEGMTAKEALK
                     TKSFYCLWVILFINITCGLGLISVVAPMAQDLTGMSPEMSAIVVGAMGIFNGFGRLVW
                     ASLSDYIGRRVTVILLFLVSIIMTISLIFAHSSLIFMISIATLMTCYGAGFSLIPPYL
                     SDLFGAKELATLHGYILTAWAIAALTGPMLLSITVEWTHNYLLTLCVFIVLYILGLMV
                     ALRLKK"
     gene            14670..15377
                     /locus_tag="ACF4ZO_000837"
     CDS             14670..15377
                     /locus_tag="ACF4ZO_000837"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HFD5486398.1"
                     /translation="MVKSYSKTANHNMRRPVVKEELVHYMRTRQKQITGFLAELEQFA
                     RQENIPIIQPEVVAYFRFLLQSLQPKHILEIGTAIGFSALLMAENAPDATIVTIDRNR
                     EMIDFAKANFAKYDSRQQIRLLEGDAADILSTLEGNFDFVFMDSAKSKYIVFLPEILR
                     LLKVGGVVILDDVFQGGDITKSIEDIRRGQRTIYRGLQSLFDATLTHPNLTTSLVPLS
                     DGLLMIRKNQADIVLPD"
     gene            15440..16495
                     /gene="prsA"
                     /locus_tag="ACF4ZO_000838"
     CDS             15440..16495
                     /gene="prsA"
                     /locus_tag="ACF4ZO_000838"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HFD5486399.1"
                     /translation="MKNSNKLIASVVTLASVMALAACQSTNDNTKVISMKGDTISVSD
                     FYNETKNTEVSQKAMLNLVISRVFEAQYGDKVSKKEVEKAYHKTAEQYGASFSAALAQ
                     SSLTPETFKRQIRSSKLVEHAVKEAAKKELTTQEYKKAYESYTPTMAVEMITLDNEET
                     AKSVLEELKAEGADFTAIAKEKTTTPEKKVTYKFDSGATNVPTDVVKAASSLNEGGIS
                     DVISVLDPTSYQKKFYIVKVTKKAEKKSDWQEYKKRLKAIIIAEKSKDMNFQNKVIAN
                     ALDKANVKIKDKAFANILAQYANLGQKTKAASESSTTSESSKAAEENPSESEQTQTSS
                     AEEPTETEAQTQEPAAQ"
     gene            16882..19500
                     /gene="alaS"
                     /locus_tag="ACF4ZO_000839"
     CDS             16882..19500
                     /gene="alaS"
                     /locus_tag="ACF4ZO_000839"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004813 - alanine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006419 - alanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HFD5486400.1"
                     /translation="MKELSSAQIRQMWLDFWKSKGHCVEPSANLVPVNDPTLLWINSG
                     VATLKKYFDGSVIPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAIEWGFELLTSPEWFDFPKDKLYMTYYPDDKDSYNRWIACGVEPSHLVPIEDNFWEI
                     GAGPSGPDTEIFFDRGEDFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPNKNIDTGAGLERLAAVMQGAKTNFETDLFMPIIREVEKLSGKTYDPDGDNMS
                     FKVIADHIRALSFAIGDGALPGNEGRGYVLRRLLRRAVMHGRRLGINETFLYKLVPTV
                     GQIMESYYPEVLEKRDFIEKIVKREEETFARTIDAGSGHLDSLLAQLKAEGKDTLEGK
                     DIFKLYDTYGFPVELIEELAEDAGYKIDHEGFKSAMKEQQDRARAAVVKGGSMGMQNE
                     TLAGIVEESRFEYDTYSLESSLSVIIADNERTEAVSEGQALLVFAQTPFYAEMGGQVA
                     DTGRIKNDKGDTVAEVVDVQKAPNGQPLHTVNVLASLSVGTNYTLEINKERRLAVEKN
                     HTATHLLHAALHNVIGEHATQAGSLNEEEFLRFDFTHFEAVSNEELRHIEQEVNEQIW
                     NALTITTTETDVETAKEMGAMALFGEKYGKVVRVVQIGNYSVELCGGTHLNNSSEIGL
                     FKIVKEEGIGSGTRRIIAVTGRQAFEAYRNQEDALKEIAATVKAPQLKDAAAKVQALS
                     DSLRDLQKENAELKEKAAAAAAGDVFKDVQEAKGVRFIASQVDVADAGALRTFADNWK
                     QKDYSDVLVLVAAIGEKVNVLVASKTKDVHAGNMIKELAPIVAGRGGGKPDMAMAGGS
                     DASKIAELLAAVAETV"
     gene            19861..20076
                     /locus_tag="ACF4ZO_000840"
     CDS             19861..20076
                     /locus_tag="ACF4ZO_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFD5486401.1"
                     /translation="MEVILKNRLKELRARDGINQTEMAKLAGVSRQTISLIERNEYTP
                     SVIIAMKIAKVFQEPVEEVFRLVEVEE"
     gene            20073..20834
                     /locus_tag="ACF4ZO_000841"
     CDS             20073..20834
                     /locus_tag="ACF4ZO_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HFD5486402.1"
                     /translation="MKKKKNSFLRLLKMSLLSSLAGGIIGGMVGAFLGYHGGRLDHLT
                     FLKDDVINLIILLNRLVVLTGLTLSFVFLTQLKKETAVYNTVEEDDISENGYRQLNKK
                     HAYTMLLIAVASILSMCNVLLGLTLTNDSQHAMLAIPLLDILLLLMVIPFQALAMKRY
                     NAIRGTDVPYFPNLKELKHNIMALDEAELQAYHKTSFESVLSLNGVIIPSLYVILFFV
                     YLFTGQVELTAILVLVLIQLYLLVKSATMTRQFYR"
     gene            20853..21548
                     /locus_tag="ACF4ZO_000842"
     CDS             20853..21548
                     /locus_tag="ACF4ZO_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HFD5486403.1"
                     /translation="MKGFINYLKIAVLIILAMVFNVLPMILLQKQHDIPMVLNWGIGI
                     FYLVIVGSVLIVLWRLYQAKQDTPIKQQKMRLVDWGYLALFWLIIRVIAIVGTLVNQL
                     WSGQQMSANDAAIHTLARLIKGGFPLYTALFVLVIAFIAPIMEELVFRGFPMIDLFKG
                     KSLKVAGLVTSLVFALPHATNSVEFIMYSCMGIFLFVAYQRRGNLKDAILLHIFNNLI
                     EVILLMSIGLGVI"
     gene            complement(21645..22795)
                     /locus_tag="ACF4ZO_000843"
                     /pseudo
     CDS             complement(21645..22795)
                     /locus_tag="ACF4ZO_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558257.1"
                     /note="programmed frameshift; internal stop; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(22933..24246)
                     /locus_tag="ACF4ZO_000844"
     CDS             complement(22933..24246)
                     /locus_tag="ACF4ZO_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HFD5486404.1"
                     /translation="MTIIIMDSNSAQETDNLSVSFLNFCYNSLMKRHFLLLTFYLFLT
                     GLTAGLVAFILTKAIHLIQSLSFGFSQGSFSTMIASVPPQRRALSLLFAGLLAGLGWH
                     LLAKKGKDIQSIQQIIQDDISFSPWTQFWHGWLQLTTVSMGAPVGREGASREVAVTLT
                     SLWSQRCNLSKADQKLLLACASGAALGAVYNAPLATILFILEAILNRWSLKNIYAACL
                     TSYVAVETVALLQGRHEIQYLMPQQHWTLGTLIWSVLAGLILSLFAHAYKHLLEHLPK
                     ADAKSQWFIPKVLIAFSLIAGLSIFFPEILGNGKAGLLFFLHEEPHLSYISWLLVAKA
                     VAISLVFASGTKGGKIAPSMMLGGASGLLLAILSQYLIPLSLSNTLAIMVGATIFLGV
                     INKIPLAAPVFLVEITGQSLLMIIPLALANLIFYFSYQFYRFILK"
     gene            complement(24221..25180)
                     /gene="nrdF"
                     /locus_tag="ACF4ZO_000845"
     CDS             complement(24221..25180)
                     /gene="nrdF"
                     /locus_tag="ACF4ZO_000845"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA];
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_process: GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HFD5486405.1"
                     /translation="MTTYYEAINWNEIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSLQEKDLVGKVFGGLTLLDTMQSETGVEAIRADVRTPHEEAVLNNIQFMESVHAK
                     SYSSIFSTLNTKKEIEEIFEWTNNNEFLQEKARIINNIYANGDALQKKVASTYLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEDEQENFR
                     DWMYDLLYQLYENEEKYTKTLYDGVGWTEEVMTFLRYNANKALMNLGQDPLFPDTAND
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGSVEAMSDDDYNYGL"
     gene            complement(25384..27543)
                     /gene="nrdE"
                     /locus_tag="ACF4ZO_000846"
     CDS             complement(25384..27543)
                     /gene="nrdE"
                     /locus_tag="ACF4ZO_000846"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HFD5486406.1"
                     /translation="MSLKDLGDISYFRLNNEINRPVNGKIPLHKDKEALKAFFAENVL
                     PNTMSFTSITEKIEYLISNDYIESAFIQKYHPEFITELAGIIKSENFRFKSFMAAYKF
                     YQQYALKTNDGEHYLENLEDRVLFNALYFADGQEDLAKDLAVEMINQRYQPATPSFLN
                     AGRSRRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     AGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGITVPDKFYELARKNEDMYLFSPYNVEKEYGIPFNYLDITNMYDELVANPKI
                     TKTKIKARDLETEISKLQQESGYPYIINIDTANKANPIDGKIIMSNLCSEILQVQTPS
                     LINDTQEFVEMGTDISCNLGSTNILNMMTSPDFGRSIKTMTRALTFVTDSSSIEAVPT
                     IKHGNSQAHTFGLGAMGLHSYLAQHHIEYGSPESIEFTDIYFMLLNYWTLVESNNIAR
                     ERQTTFVGFENSKYADGSYFDKYVTGHFVPKSDLVKSLFKDHFIPQASDWEALRDAVQ
                     KDGLYHQNRLAVAPNGSISYINDCSASIHPITQRIEERQEKKIGKIYYPANGLSTDTI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFLRSELPMELYEWKTQSKQTTRDLS
                     ILRNYAFNKGIKSIYYIRTFTDDGEEVGANQCESCVI"
     gene            complement(27563..27781)
                     /locus_tag="ACF4ZO_000847"
     CDS             complement(27563..27781)
                     /locus_tag="ACF4ZO_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin NrdH"
                     /protein_id="HFD5486407.1"
                     /translation="MITVYSKNNCMQCKMTKKFLEQHGANFQEINIDEHPEKVDYVKS
                     LGFTSAPVIEADNLVFSGFQPAKLKELI"
     gene            28174..28437
                     /locus_tag="ACF4ZO_000848"
     CDS             28174..28437
                     /locus_tag="ACF4ZO_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HFD5486408.1"
                     /translation="MASKDFHIVAETGIHARPATLLVQTASKFASDITLDYKGKAVNL
                     KSIMGVMSLGVGQGADVTISAEGADAEDAIAAIEETMTKEGLA"
     gene            28442..30175
                     /gene="ptsP"
                     /locus_tag="ACF4ZO_000849"
     CDS             28442..30175
                     /gene="ptsP"
                     /locus_tag="ACF4ZO_000849"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008965 - phosphoenolpyruvate-protein
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HFD5486409.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETVTVADTNAEEARL
                     DVALQAAQDELSVIRENAVESLGEEAAAVFDAHLMVLADPEMISQVKETIRAKQTNAE
                     TGLKEVTDMFITIFEGMEDNPYMQERAADIRDVAKRVLAHLLGVKLPNPATINEESIV
                     IAHDLTPSDTAQLNKQFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNDITKRVKDGD
                     VIAVNGITGEVIIDPSEDQVLAFKEAGAAYAKQKAEWSLLKDAHTETADGKHFELAAN
                     IGTPKDVEGVNDNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDLPKEMNPFLGFRALRISISETGDAMFRTQMRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADDIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDSAKMEEYANRALTECSTAEEV
                     LELSKEYVSED"
     gene            30360..31787
                     /locus_tag="ACF4ZO_000850"
     CDS             30360..31787
                     /locus_tag="ACF4ZO_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019322885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HFD5486410.1"
                     /translation="MAKQYKNLVNGEWKLSENEITIYAPATGEELGSVPAMTQAEVDA
                     VYASAKKALSDWRALSYVERAAYLHKAADILVRDAEKIGAILSKEVAKGHKAAVSEVI
                     RTAEIINYAAEEGLRMEGEVLEGGSFEAASKKKIAIVRREPVGLVLAISPFNYPVNLA
                     GSKIAPALIAGNVVALKPPTQGSISGLLLAEAFAEAGIPAGVFNTITGRGSVIGDYIV
                     EHEAVNFINFTGSTPIGEGIGKLAGMRPIMLELGGKDSAIVLEDADLALAAKIIVAGA
                     FGYSGQRCTAVKRVLVMDKVADQLAAEIKTLVEKLSVGMPEDDADITPLIDTSAADFV
                     EGLIKDATDKGATALTAFNREGNLISPVLFDHVTTDMRLAWEEPFGPVLPIIRVTTVE
                     EAIKISNESEYGLQASIFTTNFPKAFGIAEQLEVGTVHLNNKTQRGTDNFPFLGAKKS
                     GAGVQGVKYSIEAMTTVKSVVFDIQ"
     gene            31882..33156
                     /locus_tag="ACF4ZO_000851"
     CDS             31882..33156
                     /locus_tag="ACF4ZO_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HFD5486411.1"
                     /translation="MKKLNVILVGLLSILMLSLAIVFINRWKLNEDSQRIVLAEKKKN
                     TSDLVIKAVKHIKKDQKDYYYFSPIKQADDFFVDNLPVSLYKKKNSDKELILVKPKLQ
                     SSHLRSVNTLTISKIVYQKKFFHLAKKSEKVISTYHVTDDLKPFQVKDLVSGHLERIQ
                     EEIEKKYPNAGFNSDKYNGLKESNSLLSDGFEVKSGNLIFDKKLTIPLTTLFDVINPD
                     FLANSDRAAYDNYRTYKEQHPKKLVALTFDDGPDPTTTPQVLDILAKYQAKGTFFMIG
                     SKVVDNENLTKRVSDAGHEIANHTWDHPNLTNLSVSEIQHQVNMTNQAIEKACGKKPR
                     YLRPPYGATNATVQQSSGLTQMLWTVDTRDWENHSTDGIMTNVKNQLQPGGVVLMHDI
                     HQTTINALPTVMEYLKAEGYECVTVSELYAHQ"
     gene            complement(33267..34352)
                     /locus_tag="ACF4ZO_000852"
     CDS             complement(33267..34352)
                     /locus_tag="ACF4ZO_000852"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HFD5486412.1"
                     /translation="MITKFPPQWQEKLDQVAFTHLTPIQEQAFQPIVDGKNFLGISPT
                     GTGKTLAYVFPSLLALTPKKSQQLLILAPNTELAGQIFEVTKDWAQSLGLTAQLFISG
                     TSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMSVNTIVLDEYDELLGDSQYDFV
                     QKISHYVPRDHQMVYMSATNKVDQTSLAPNTFCIDLSEQTNDAIQHFYLMVDKRERTD
                     LLRKFANIPHFRALVFFNSLSDLGATEERLQYNGAAAVSLASDINVKFRKTILEKFKS
                     HQLSLLLATDLVARGIDIDNLDYVIHFDVARDKENYTHRAGRTGRMGKSGIVITFVSH
                     PEDLKKLKKFAKVSEISLKNQQLHFIN"
     gene            34450..35076
                     /gene="udk"
                     /locus_tag="ACF4ZO_000853"
     CDS             34450..35076
                     /gene="udk"
                     /locus_tag="ACF4ZO_000853"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004849 - uridine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HFD5486413.1"
                     /translation="MLKKPIIIGVTGGSGGGKTSVSRAILDSFPNARIAMIQHDSYYK
                     DQSHMSFEERVKTNYDHPLAFDTDFMIQQLKELLAGRPVDIPIYDYKKHTRSNTTFRQ
                     DPQDVIIVEGILVLEDERLRDLMDIKLFVDTDDDIRIIRRIKRDMMERGRSLESIIDQ
                     YTSVVKPMYHQFIEPSKRYADIVIPEGVSNVVAIDVINSKIASILGEV"
     gene            35156..35419
                     /locus_tag="ACF4ZO_000854"
     CDS             35156..35419
                     /locus_tag="ACF4ZO_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HFD5486414.1"
                     /translation="MLLIWLGLLFVWNELVFVIYAFDKRKAIKKKRRISERNLLVITI
                     LFGGFGALLAAKKYHHKTRKWYFVITWYTSILLTLLVTYIFMK"
     gene            complement(35472..36281)
                     /locus_tag="ACF4ZO_000855"
     CDS             complement(35472..36281)
                     /locus_tag="ACF4ZO_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HFD5486415.1"
                     /translation="MKQITQQKWLRYGLFIALVLNGIELELLGLTANNLSFKEAFALI
                     LTISLLGIYLIPFAAAIFYLSKKFHMNLNVIIVSCLSGLYISGFLASCGNHLVGQFWS
                     YIIPSKDALKLWGDALTAPIVEEPIKASSAILVITLFPRLTLKEKLVVALLSGMGFQL
                     TEDIRYLIQAKSIDSLVPTAIERISTAVTSHWVHTAIFTIGAYLLLKGSNLFSKQQQI
                     FWLLSPLVLHFIWNSPLTSIPGMTVLLGTLILLIFGDLFQKINTLDDDVLF"
     gene            36426..36923
                     /locus_tag="ACF4ZO_000856"
     CDS             36426..36923
                     /locus_tag="ACF4ZO_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0033745 - L-methionine-(R)-S-oxide
                     reductase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HFD5486416.1"
                     /translation="MNKSKKIEQYQLMIAQAKELFANESNALANLSNASALLNMTLPN
                     SVFTGFYLFDGQELILGPFQGRVSCVHIKLGKGVCGESAQSRRTIIINDVKQHANYIS
                     CDAAAMSEIVVPMVKEGHLIGVLDLDSSLVADYDEVDQEYLETFVDLLLEKTTFTFNM
                     FGVKN"
     gene            36923..38593
                     /gene="dnaX"
                     /locus_tag="ACF4ZO_000857"
     CDS             36923..38593
                     /gene="dnaX"
                     /locus_tag="ACF4ZO_000857"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HFD5486417.1"
                     /translation="MYQALYRKYRSQTFDEMVGQSVISTTLKQAVESGKISHAYLFSG
                     PRGTGKTSAAKIFAKAMNCPNQVDGEPCNQCDICRDITNGSLEDVIEIDAASNNGVDE
                     IRDIRDKSTYAPSRATYKVYIIDEVHMLSTGAFNALLKTLEEPTENVVFILATTELHK
                     IPATILSRVQRFEFKAIKQKAIREHLAWVLDKEGIAYEVDALNLIARRAEGGMRDALS
                     ILDQALSLSPDNQVTIAIAEEITGSISILALGDYVRYVSQEQATQALAALETIYDSGK
                     SMSRFATDLLTYLRDLLVVKAGGDNQRQSAVFDTNLSLSIDRIFQMITVVTSHLPEIK
                     KGTHPRIYAEMMTIQLAQKEQILSQANLSGELISEIETLKNELAQLKQQLSQLQSRPD
                     SLARSDKTKPKTTSYRVDRVTILKIMEETVRNSQQSRQYLDALKNAWNEILDNISAQD
                     RALLMGSEPVLANSENAILAFEAAFNAEQVMSRNNLNDMFGNIMSKAAGFSPNILAVP
                     RTDFQHIRKEFAQQMKSQKDSVQEEQEVALDIPEGFDFLLDKINTIDD"
     gene            38688..38891
                     /locus_tag="ACF4ZO_000858"
     CDS             38688..38891
                     /locus_tag="ACF4ZO_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015631927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 family protein"
                     /protein_id="HFD5486418.1"
                     /translation="MTIRQFLFMAFVCAFETYFFNDLLLSGNYLFALFWGLLLFRDLR
                     RVHTINQLTKTILKAANSPKKKD"
     gene            complement(38866..39807)
                     /gene="birA"
                     /locus_tag="ACF4ZO_000859"
     CDS             complement(38866..39807)
                     /gene="birA"
                     /locus_tag="ACF4ZO_000859"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     ligase/biotin operon repressor BirA"
                     /protein_id="HFD5486419.1"
                     /translation="MKTSEKIYQLLSQTDDFVSGEYLADQLSISRTSVWKSIKSLENQ
                     GIQIDSLKHKGYRMVQGDILLPKTISQGLGMPVTYTPHSQSTQLDAKQGIEAHNSAPR
                     LYLAPSQEAAKGRLDRQFFSASTGGIYMSMYLKPNVPYADMPPYTMMVASSIVKAISR
                     LTGIDTEIKWVNDIYLGNHKVAGILTEAITSVETGLITDVIIGVGLNFFVTDFPEAIA
                     QKAGSLFTEKPTITRNDLIIDIWKLFLSIPVKDHVKVYKEKSLVLNKQVTFIENSQEK
                     RAIAIDLTDQGHLIVQFDNGDLQTLRSGEISLSSWEN"
     gene            40010..42388
                     /locus_tag="ACF4ZO_000860"
     CDS             40010..42388
                     /locus_tag="ACF4ZO_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine-rich repeat domain-containing protein"
                     /protein_id="HFD5486420.1"
                     /translation="MKTKKVIILVGLLLSSQLTLISCQSRGNGTYPIKTKQSRKGMTS
                     NKIKPIKKSKKTNKTHKGVAGVDFPTDDGFILTKDSKILSKTDQGIVVDHDGHSHFIF
                     YADLKGSLFEYLIPKGASLAKPAVAQQAASQGTSKVADPHHHYEFNPADIVAEDALGY
                     TIRHDDHFHYILKSSLSGQTQAQAKQVATRLPQTSSPVSTATANGIPGLHFPTSDGFQ
                     FNGQGIVGVTKDSILVDHDGHLHPISFADLRQGGWAHVADQYDPAKKAEKPAETHHTP
                     ELSEREKEYQEKLAYLAEKLGIDPSTIKRVETQDGKLGLEYPHHDHAHVLMLSDIEIG
                     KDIPDPHAIEHARELEKHKVGMDTLRALGFDEEVILDIVRTHDAPTPFPSNEKDPNKM
                     KDWLATVIKLDLGSRKDPLQRKGLSLLPNLEILGLGFTPIKDISPVLQFKKLKQLLMT
                     KTGVTDYRFLDNMPQLEGIDISQNNLKDISFLSKYKNLTLVAAADNSIEDIKPLGQLP
                     NLKFLVLSNNKISDLSPLASLHQLQELHIDNNQITDLSPVSHKESLTVVDLSRNADVD
                     LATLQAPKLETLMVNDTKVSHLDFLKNNPNLSSLSINRAQLQSLEGIEASSVIVRVEA
                     EGNQIKSLVLKDKQGSLTFLDVTGNQLTSLEGVNNFTALDILSVSKNQLTNVNLSKPN
                     KTVTNIDISHNNIPLADLKLNEQHIPEAIAKNFPAVYEGSMVGNGTAEEKAAMATKAK
                     ESAQEAPESHDYNHNHTYEDEEGHAHEHRDKDDHDYEHEDENEAKDEQNHAD"
     gene            42925..44121
                     /gene="metK"
                     /locus_tag="ACF4ZO_000861"
     CDS             42925..44121
                     /gene="metK"
                     /locus_tag="ACF4ZO_000861"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004478 - methionine adenosyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006556 - S-adenosylmethionine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HFD5486421.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAEDPEAHVAAE
                     TCVYTGSVHVFGEISTTAYIDINRVVRDTIAEIGYTEAEYGFSAESVGVHPSLVEQSG
                     DIAQGVNEALESREGDTDDLSHIGAGDQGLMFGFAINETPELMPLPISLSHQLVRRLA
                     ELRKSGEISYLRPDAKSQVTVEYDEHDKPVRVDTVVISTQHDPEATNNQIRQDVIEKV
                     IKAVIPADYLDDDTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFSG
                     KDATKVDRSASYAARYIAKNLVAAGLATKAEVQLAYAIGVAQPVSVRVDTFGTSTVPE
                     AVLEAAVRQVFDLRPAGIIQMLDLKRPIYKQTAAYGHMGRTDIDLPWERLNKVDALVE
                     AVKTVL"
     gene            44295..>45227
                     /locus_tag="ACF4ZO_000862"
     CDS             44295..>45227
                     /locus_tag="ACF4ZO_000862"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HFD5486422.1"
                     /translation="MRKIIINGGKALSGEVAVSGAKNSVVALIPAIILADDIVILDGV
                     PAISDVDSLIEIMELMGATVNYHGDTLEIDPRGVQDIPMPYGKINSLRASYYFYGSLL
                     GRFGQAVVGLPGGCDLGPRPIDLHLKAFEAMGVEVSYEGENMNLSTNGQKIHGAHIYM
                     DTISVGATINTMVAATKAQGKTVIENAAREPEIIDVATLLNNMGAHIRGAGTDIITIQ
                     GVQKLHGTRHQVIPDRIEAGTYIALAAAIGKGVKITNVLYEHLESFIAKLEEMGVRMT
                     VEEDAIFVEKQKSLKAITIKTSPYPGFATDLQQPL"
BASE COUNT        14412 a         7829 c         9319 g        13667 t
ORIGIN      
        1 gctagcgatt tggttgagaa agtggcacaa gcacaaaata ataaaacaga tgctcaaaat
       61 aatccaaaga agcttgtgca aaacacaaat ctaccaaaga ccggagccgg agatggttta
      121 aatccattcc tgcatgaaat gatactagga atatccggac ttgcacttgc tatcacagga
      181 tacttcagaa agaaacacgc gaaataagct agcgtagtaa tcaacataat attagataat
      241 gcctactacg gagaaatcct tggtaggcat tactttttta tattcttttt taaatttttg
      301 gttcttaaaa ttatcttttc tgtccgttta ctgatagagg aggtaatgga gatgcaaaaa
      361 tataaaaaag aaccaaggac gtcggcgtac tttgatgggg gagatttcct tatctgttgt
      421 caaaaaaaca gtatgaaaac tctctttgaa aagaggggag ttagcttatg aatgtagaag
      481 aaaagaatct gataagagaa cttcgagaaa aagctcttgg atataaaaga atttccggtg
      541 aacttggaat cagtgtcaat acgattaagt cgttttgcag gaatcacaag ttaactcgtg
      601 agcatattgt tagaacaatc tactgtaaag agtgcggaaa agagttaatt caaaaggaac
      661 acaccaagaa aaaaatcttt tgctcagatg catgtaaaag gaagtggtgg aatggacatc
      721 gaaaaagttt aagtaagact accatggaag aatatatctg tctgaactgc cataaaaaat
      781 ttaaggctta tgtagcagaa catagaaaat actgttgtca ctcctgctat atcaaggcaa
      841 gatttcaagg tagtgatgac catgaataag gaagaacacg ctgaaataat gtaccaatta
      901 tccatatcca ttgccgaaag aatgtatgaa aatcatcttt taaataaggg ataaaaatat
      961 ggaaaggcta cgattttact tattctgcca taaatgtcat tctaagaaat gaaatttata
     1021 taggggatcg aaggatgcaa aagacttccg taaaaggccc catcaaacag aataaggtga
     1081 aaaataaggg agaattacca cagtattatg tggaaaacaa ccataaagcc attgtagata
     1141 aagagacttt tgacgcggtt caagcagtac tagataggac agaaaagggc aagggcagca
     1201 ccacactatt ttgttcaaag ctggtatgtg gggattgcgg gcattacttt ggtagtaagg
     1261 tatggcattc cacatcaaaa taccgaaggg ttatctacca atgtaatgag aaatacaagg
     1321 gtgaaaagaa gtgcaccaca ccacatgtta ctgagaatga gattaaggat tggttcgttt
     1381 cagtaatcaa taaggttatc agcaataagg atgagattat ccagaaccta gaaatgttac
     1441 ttgacgttgg gaaaagttct gaccttgaaa gaatttttag agacactcaa tcagcaaagt
     1501 gagcttataa gtgagtttga tgagttgctt tgggaaactg tagtagataa agttgagatt
     1561 tgccaaaacc gcatagtaac ttttacattg aaaaatggta gtgaagttgt agcttaatgc
     1621 tacgacttat tttaatataa ttgtgatagg aggtgtaaga tgtttaattt tacaaagaga
     1681 ctttttccga aaagtagaga caataaagga atctaccata cagattcgcc actgtatttt
     1741 aataatgtgg aagatttttg tttttcttaa aggcaaaaga tgttagtata gtggatggac
     1801 caattgcgga agctgtgata catgtgcaaa aaatcacttc tgaacagatt gaatttcatt
     1861 ttgggtggat tacaagtgta tcaggaattg gtggcaatga atatttcgga ggaatgacct
     1921 acctagttgc aacaataatc tatatcatac ttaacgatag tagtcttaag aatcgtatga
     1981 taagaatatc tttagatatg caatcagaag cacgagaggt tgctattaac agaaagatag
     2041 atgtttatca caaatttttt aaaactccta aaaatatttc tgatgtatct gaattttcct
     2101 ttcatagggt tgcaacattt tcaccggaga atagaaagca cgatttagag tatttcaaag
     2161 ggataataga agaaaaagaa aaatcaatat tatctgtact tgattcatat agatgagtat
     2221 tctgggttgt tttaaattgt atcaatttaa gtacacatac cgatactgat catatggggg
     2281 atatcgaagt ggttgccaaa gctattcgga taaaggagat tttgactagt caaggcagtt
     2341 taagccagcc aagctttgtt aggcggctaa ggcgtttaaa atgtcgtgtt agggttttag
     2401 cagctggaga ccagttgcct attatgggaa atgtcttaca ggtactctac ccttggcagt
     2461 taggggacgg gaaaaataac gattctttgg tactttatgg caggctctta aatcaaactt
     2521 ttttatttac aggtgatttg gaaaaagagg gggaaaacga gatcataaaa cgttatcctc
     2581 aactaagagt agattattta aaagcaggtc accatggatc aaatacctct tctagtgcag
     2641 cttttttaga ccatattcag cctaaagtgg cctttatttc tgctggaaaa aataaccgtt
     2701 atcagcatcc tcacagagaa accttagccc gtttagagga tagggaaatt tcttattatc
     2761 gcacggatat tcaaggagct attcggttga caggatggct aaattggcat attgagactg
     2821 ttcgttgagc aggggaaagt gcattaattt cttaacacct tgatgccagg tcggtagctt
     2881 ttcttttgaa agatgatata ataaaagcat gattgcgata gaaaagatag agaaactgaa
     2941 taaacaaaat ttaggcctca ttaccttggt aactggagaa gatattggtc aatatagcca
     3001 attaaaatcg cgtttaatga cgcaaattgc ttttgataag gatgatttgg cctattctta
     3061 ctttgatatg tctgaggccg cttatcagga tgcagaaatg gatctagtga gcctaccctt
     3121 ctttgctgag cagaaggtgg tcatttttga ccatttgtta gatatcacga ccaataaaaa
     3181 aagtttctta aaagaaaaag acttaaagac ctttgaagcc tatttagaaa atcccttaga
     3241 gactactcga ctaattatct ttgctccagg taaattggat agtaagagac ggcttgttaa
     3301 gcttttgaaa cgtgatgccc ttgttttaga agccaaccct ctgaaagaag cagagctaag
     3361 aacttatttt caaaaataca gtcatcaact gggtttaggt ttcgagagtg gtgcctttga
     3421 ccaattactt ttgaaatcaa acgatgattt tagtcaaatc atgaaaaaca tggctttttt
     3481 aaaagcctat aaaaaaacgg gaaatattag cctaactgat attgagcaag ccattcctaa
     3541 aagtttacaa gataatattt ttgacttaac cagacttgtc ctaggaggta aaattgatgc
     3601 ggctagagat ttgattcatg atttacggtt atctggagaa gatgacatta aattaatcgc
     3661 tatcatgcta ggccaatttc gcttattttt gcagctgact attcttgcta gagacgtaaa
     3721 aaacgagcaa caactagtga ttagtttatc agatattctt gggcggcggg ttaatcctta
     3781 ccaggtcaag tatgcgttaa aggattctag gaccttatct cttgcctttc taacaggagc
     3841 ggtgaaaacc ttgattgaga cagattacca gataaaaaca ggactttatg agaagagtta
     3901 tctagttgat attgctctct taaaaatcat gactcactct caaaaatagg cattggaccg
     3961 ctttccaaga gataatcaaa ttagttgaaa gctcttattt tttgcgataa gatagacgta
     4021 tcataaagga aaagaggaca ggaaaatggc tattatttta ccagaacttc catacgcgta
     4081 tgatgctctt gaaccacagt ttgatgcgga gacaatgact cttcatcatg ataaacacca
     4141 tgccacttat gttgccaatg cgaatgctgc tttagaaaaa cacccagaga tcggagaaaa
     4201 cctcgaggaa ctattggcag atgtcactaa gattccagaa gatattcgtc aagccttaat
     4261 taataatggt ggcggacacc taaaccatgc gcttttctgg gaactattat caccagaaaa
     4321 acaagacatc actcctgatg ttgcacaagc cattgatgat gcttttgggt catttgacgc
     4381 ctttaaagaa caatttacag cagctgctac tggacgtttt ggttcaggtt gggcatggtt
     4441 ggttgttaat aaagaaggac aactcgaaat cacatcaacc gctaaccaag atactccaat
     4501 ttcagaaggc aaaaaaccaa ttctagcact tgatgtgtgg gagcatgctt actacttgaa
     4561 ttatcgtaat gtacgtccaa attatatcaa agctttcttt gaaatcatta attggaaaaa
     4621 agtatcagaa ctttaccaag ccgctaaata agaaaagggt ttccaatctc aaaaagagat
     4681 tggtttttta agtgtttttg tgaataacag tgtggggaca tcatttttta gaaaagataa
     4741 aaatagtttg tctttttaat gtaattcctt gatttttagc taaatttagc tagaatagaa
     4801 tggataggag attttaagtg ttaagagaga agaaaactac cattgtaggg attattttag
     4861 gaatgatgat agtgacctta cttgtcggct gtttgactgg taaaaagaaa ggctttcctc
     4921 ctaaagcagg taagcggcag caaacggctg aaaagcaaga ttagaaaaac tgtttaaaaa
     4981 ccgttacctg aaaaatctaa agaggctaag caagctgtta tggatacaga tttagtggaa
     5041 atggatgcct tagggctcta ttacgatgac aaccatttga gtttggtcaa tacggtcaag
     5101 gcgtatttaa aggaatttgg cattggtgaa tcccaaattg ccttttccta caaagacctc
     5161 aattcagtta ggactgttgc catgaatgac catcagccaa tgattgcagg aagcacctat
     5221 aagctgccat taaacatgct ggtggtaaat tatccatgac agagcgtttt gacattacag
     5281 aaactgatta tgaatatgat caggaacatc atgcctatgt tgctcaattc aatggtgcca
     5341 tgtctatttt ggatatgcaa gaatattctt tggtgtactc agaaaacacg ccagcttatg
     5401 ctctagcaga acgattgggt ggcatgaata aggcttacca attatttgac cgctacggga
     5461 aggtatccgg ggctattacg accattgatc gtaatggcaa taaaatcacc accacttact
     5521 atttgcaagt tttggattac ttgtggcagc atcaggataa atataaggat atcttgtact
     5581 acattggtga atctttccct gatttgtatt acaagactta tttgcctcat gtaaaggttt
     5641 atcaaaaacc gggttatgtc agagaagcct taaatgtagg tgccattgtt tgcgaagagt
     5701 ctccttattt gattgctctt tattcatctg gtttgggtgg agcaacacaa gcatcagagg
     5761 aagtcaatgg ccttggttat gtgcagcttg ttcagctaac atacgtaatt aatgagtggc
     5821 atagagtcaa tcacaacatg atctaatact cagttgacat tagtctgata gtagacatac
     5881 ttactgatga aagtcactaa aataagtttt tgctcattaa aaaagcttgg cctgtttctt
     5941 caggtcaagc tttttgagat taatgctgtg tttttgaggt cttattgtca cctcttgttt
     6001 cttgataatg gtgaagcaat tttttgaatt ttttaacggc agcgcgtgtt agctgcttag
     6061 atgatttgcc atttctgctg taaatgggat tgtgcttatc cctttgctgt tctaaatcgg
     6121 gaactagaaa agttgcatca ggactattag ttgctttttc aataaaagcc ggatcaaaaa
     6181 gcagaatagg gtcaatatca agcagacggt gcaagtcatc gttttggttg ccataattga
     6241 aagaagaacc attgacaata ctatttcgcg ttaggttatc aggatctagt gctactaaaa
     6301 attgtccaga ttctgacaaa ataaactctg agtgaaaatg aatcaaaatc ttatagttgg
     6361 cttgaggaat attgtctgta tagactgcct gatgattgcc attagaatct aaaatactag
     6421 caaccttatt atggtatcta gaagattcat aaagagcata atcgtcatct tctagagtag
     6481 ccaaatattt ggctaaggca tccgcatcgg ttttcccttt attcccataa tgtgagcgaa
     6541 cccactccat ttgctgggtt gatatgaggt aacggagttg atgaattttc cgattaaaac
     6601 ggctataagg aatgtgttcg agattaacat aacaagcctg aatcagggca gataattggt
     6661 cccaaaaagg atctgttggc gatagctttg gacttaattg tgccaatact tgctgtgttt
     6721 gttttgattg tcctgtcaac tcgtctggca tctttaaata cgtcaagagc agctgtagcc
     6781 gtttttgagc ttcttgaggc gtctgtgcca tctcttcttg ttgccagagc ttttgaaagt
     6841 caggtgatcc tatcaggcga atgcgactat aaagttgttc gaaatgataa gagtttcctc
     6901 taacagcgag ttgttcaagg tatccttttt ggatggcttt ataggaccat ccgtccttat
     6961 cgagttttcg aacataatca agcaagtcgt ggcgtaattt aatagcttct gaaagctgga
     7021 gttctcgtaa tttaggatag ttttggtaaa aaggtgccac taaatcttga taaagtttgt
     7081 gttctttttc aaaagcaatc cgctgatagt ctttctgcca aaaactgacg caaaaagtca
     7141 gaaacatcaa gaagaatagc cattttccaa gtaatttcat aggtttttag ttgacaaaca
     7201 tggcatcgcc aaagctaaag aaacgatact tttcgtcaat cgcgtgtctg taagcttcaa
     7261 ggacaaagtc acgccctgca aaggctgata ctagcatcac aagggttgat tttggaagat
     7321 ggaaattagt tgaaaaagca tcaactacct tgaattggta gcctggttta ataaaaatat
     7381 tggtccaacc tgaatcagct tgaatgtccc cttggaactt acttccgatg gtttccaacg
     7441 tacgaataga ggtggttcct acagcgacaa cacgaccgcc agcttgtttg acgtctctta
     7501 gggtttgcgc tgcttcttct gagagggaat aaaattccga atgcatatca tgctcatcga
     7561 ggttatccac ggaaacaggt ctaaaagtcc caagccctac atgtagggtc aaataaacca
     7621 aatgtacccc tttggcttcg atttttttga gcaagtctgt tgtgaagtgg agaccagcag
     7681 ttggggcggc cgcagagcca ttttctttag cataaacggt ttggtatcgc tcagcatcct
     7741 ctaatttttc gtgaatataa ggaggcaatg gcatttcgcc gaggctctct aaaacttcta
     7801 agaaaatccc atcatagctg aattcaacaa ttcgtccacc atgttctaat tcgtcgataa
     7861 tggtggcttt gagacgccca tctccaaaat tgacttggct accaaccttg agccgtttgg
     7921 ctggcttggc taaaacttcc cattgatctc cttgtgtatt tttaagcaaa agcaattcca
     7981 catgaccatg agtatcgggt ttttctccat aaagtctggc aggtaagaca cgggtgttat
     8041 tcatgacgag ggcatcccct ggatttaatt gatcaatgat atggtcaaaa tggctatcaa
     8101 ccatagtttt ttgacggtga tcaataatca atagttttga actgtctctt ttttcgagtg
     8161 gggtttgggc aatcaattct tctggtaact caaaatcaaa atcgttagta ttcattggga
     8221 ctcctttaaa gccactagta aatctcttcc taataactct ttcatgtaag ataaatcttt
     8281 tctattatat cacttgttgt ctaacccgtc atctttaatc tttcatcaga aaggaaaaga
     8341 taggcttgac aaaaattggt atataccata taataaaaac acgaaaggtc tataccaatt
     8401 agaaaaggag aatgacatga aaattattcg ggtccaagat cagattgaag gtgggaaaat
     8461 cgcttttacc ttattgaaag atagcttagc taagggagct aagacgttag gattagcaac
     8521 aggaagttca ccaattagtt tttaccaaga aatggtcaaa agtcgtttgg atttttcgga
     8581 cttaacaagt attaacttgg atgaatatgt cggtctttca gtagagagcg atcagagtta
     8641 tgattatttt atgcgtcaaa acctttttaa tgcgaagcct tttaaaaaga attacttgcc
     8701 caatggttta gcaaccgatg tcgaagcaga agctaaacga tatgaccaaa tcattgcaga
     8761 gcatccgatt gattttcaag tgcttgggat tggacgtaat gggcacattg gttttaacga
     8821 acctgggact tcttttgaag aagaaacgca tgtggtggat cttcaagaat caaccattga
     8881 agccaatagt cgtttcttta caagtattga tgatgtccca aaacaagcta tttctatggg
     8941 cattgcttct atcatgaagt ccaaaatgat tgttcttctt gcctttggac aagaaaaagc
     9001 tgatgcgatc aagggaatgg tttttggacc aatcacagaa gacctcccag caagtattct
     9061 ccaaaaacat gatcatgtta tcgtcattgt ggatgaagct gctgcgtcac aattagacta
     9121 acctaaccag tcgttaaacc ttgtaagaac aaaaatgagg agttagtcaa cctcatttaa
     9181 gaagaagtct tgtaacttct atttcttttg caagagtaaa tttatgttac actactaata
     9241 tgcgtttaga taaattatta gaaggtacaa aagttggctc tagaagtcaa gtgaagaaac
     9301 tgattaaggc tcaaggggtt tgggttgatc acatgcctgc cagaaatggt cgacaaaatg
     9361 ttgatcctgg cttgcaactg attgaggtga ctggacagcg agtgacgcat cctaaacatt
     9421 cctacattat cctcaacaag ccatcagggg tggtctcagc taagaaagat actaactatt
     9481 taaccgttat tgatcagctt gctgaagaag ataaaagtcc agacttgtat cctgttggta
     9541 gattggatag ggataccgaa gggttggttt tactcactga taatggtccc ctagggtttc
     9601 ggatgttgca ccctagtcat catgtttcta aaacgtatct tgtaaccgtt aatggcttgt
     9661 tagcagaaga tgcctcagat ttttttgcag ctggtatttg tttcccaaca ggtgaacaat
     9721 gccaaccagc tcaattgact attcttaaag ccgacataga ccagtcacag gctagtttga
     9781 ccatttcaga aggaaaattt caccaagtga aaaaaatgtt tttgacctat ggtttgaaag
     9841 tgacctctct gaaacggacg cactttgcag gactggaact cggtcattta gccagcggag
     9901 aatatcgtta tctaacagag tcagaaaggc aactcattaa aacgtatcta gactgagcaa
     9961 aacatgcttt caaaaagaag ctattcttgc ttaatcaata aagtgtccat tgactattat
    10021 agtcatgatg agttcgactt ttgctatgtt tagtcatctt gttgttacaa aatcgggtaa
    10081 gcaaaaagat tcaattccca ctgtctcctt aacctgaagc gttataaaaa cccttgtgtt
    10141 aaactctcat aaattggaaa tgggggtgtt tttttgatgg ctaaaaaaac taaagctact
    10201 taaagtttgg tacttagttt tcgaataata aggtggaaga tctaatagga ggtgacaaaa
    10261 atattaaccg ctttagatgg taagaatcag ctcatttcgc tagtaactca gcctatttca
    10321 acgaaaccgc cttttcgttg cccagcttgc aaatctcctg ttcgcttgcg tcaggggaca
    10381 attagacgac ctcattttgc ccatgtacaa ctagctcatt gtcaattcca agcagaaaat
    10441 gaatctgagg aacatttgac gttgaaggca aaactttaca ccagtttagt ccgaacagaa
    10501 gctgtctgta ttgaaaaata tcttcctgag ctgcaacaga tagcagacct ttgggtgaat
    10561 gataagttag ccttagaaat tcagtgcagt cccttgccag ttgagcgtct aaagaaacgc
    10621 accaaagcct atcaagaaaa ggggtatccg gtacgatggt tactgggaag aaaattgtgg
    10681 cttaacactc acttaactgc tttgcaaaaa cagtttcttt acttttcatc tagtttgggc
    10741 tttcatttgt gggagctgga tgcagctgca aatctgctac gtctcaaata tttaatccat
    10801 gaagacttat ttggtaaggt aagttaccta accaaaacca tttctttaga ccataatatt
    10861 atggaaatgt ttcggttacc ctatcagcaa gaaatccttt attcttatca gaaaaaaatg
    10921 actgtgaacc tatctaaaag aatacaaaga gctcttttag ctagacaccc gaaatggcta
    10981 cgacgacaag aaaaggctta cttatcaggc tataatttac ttatgttaac aactgatgct
    11041 ttttatcctc aatggagacc agttcaatct tccagcggtt tttgtcaaat taaaggaaat
    11101 cttcgccctt attatgaaag ttttaaagtc tattacaaaa aagaaaagga taagaaggtg
    11161 caaacgcttt tttcaccaaa atattatgtt aaaatggata gtaatagaaa ataagaagga
    11221 gatgttatga ctgataatcg cagccattta gaagaaaaat acacttggga tttgagcact
    11281 atttttgcaa cagataagga ttgggaagct gaagtcagtg acttagctac tgaagttgag
    11341 gcatctaaag gttttgctgg tcatttgctg gattctagtg ctaatttgtt aaaggttaca
    11401 aaaacatatt tagaattggc tcgtcgtgtg gagaaagtct atgtttatgc tcacatgaaa
    11461 aatgaccaag acactactgt tgccaagtat caagaatacc aagctaaggc ttcaggcttg
    11521 tatgcaaagt ttagcgaagt cttttcattc tatgatccag aagtgatgat gcttcatcaa
    11581 gaagactatc aggctttcct tactgaaacc cctgagttga aagtgtacaa ccatttcttt
    11641 gacaaattat tccaagcccg cgaacatgtt cttagtcaag cagaagagga attattagca
    11701 ggagctcaag aaattttcaa tggtgcggaa gaaaccttta gtattcttga taacgctgac
    11761 attgttttcc cgatagtcag aaatgataaa ggtgaaaacg ttgaattaac ccatggtaac
    11821 ttcattagcc taatggaatc taaggaccgt agcgttcgcc aagctgctta tgaagccatg
    11881 tatagtactt atgaacagtt ccaacatact tacgctaaaa ccttgcaaac caatgtgaaa
    11941 gtgcaaaact ataaggcgcg tgttcataaa tacgattcag cacgtcaagc tgccatggct
    12001 gctaacttta ttccagaagc tgtttacgac actttattag aaacggttaa caaacattta
    12061 ccactcttac accgttattt gaaattgcgt caagaggttc ttggtttaga cgatttgaag
    12121 atgtatgatg tttacacacc attatctgaa acagatctag ccattggtta tgatgaggct
    12181 ttggaaaagg ctgagaaggt tttggctgtt tttggtaaag attacgcaga tcgtgtgcat
    12241 cgtgctttta ccgaacgttg gattgatgtt catgtcaata aagggaagcg ttctggagct
    12301 tattcgggtg gttcctatga taccaatgcc tttatgctat taaactggca agatacctta
    12361 gacaatctat acactttagt tcatgaaact gggcacagtt tgcattctac tttcactcgt
    12421 gaaacacagc cttatgtgta tggagattac agtattttct tggcagaaat tgcatccaca
    12481 acgaatgaaa atattatgac agaagctctc ttaaatgagg ttcaagatga gaaagaacgc
    12541 tttgccattt taaaccatta cctcgatggt ttccgtggaa cagttttccg tcaaacccaa
    12601 tttgctgagt ttgaacatgc cattcatcaa gctgatcaaa aaggagaagt gttaacaagt
    12661 gaatacctta accagctata cgctgattta aatgaaaaat attatggttt aagtaaaaaa
    12721 gataatcatt ttattcagta tgaatgggca cgtattcctc atttctatta caattattat
    12781 gtttaccaat atgcaacagg ttttgcagct gcaagctatt tagcggataa gattgtgcat
    12841 ggcacacaag atgatatcga tcattacttg gcctacctca agtcaggaaa ttctgattac
    12901 ccacttgaag tgattgctaa agcaggcgtt gatatggcaa aaggtgatta tttggaagcc
    12961 gcctttaaag tctttgacga acgtctaaca gaacttgaag tactcgtgtc caaaggcata
    13021 cacaaaagct aaaatcacaa aagtcaagga caaaaagagt ttaggattga tagaaatgga
    13081 gattcacagt tggtgtgaat ctccatttct atcggtcatt ttctttttat attttagtgg
    13141 attatcagtc ctgaaaagca ggcttcattg accttagttt gacggtttct tttttgtctt
    13201 ttttattgtg tggtcactaa cttaaataaa accaatagtt gagtaaggcg cttcagatta
    13261 acgctattct attgttttag agataacgtt cgcataaaac atatttttat tatatttgac
    13321 attttataaa agagataata gtattaaaat actaacattt atgtttttta aaaagtaaac
    13381 gttcgtataa taaaaaagga gtttttcatg gaaaaaacaa aacgttatat cattgcaaca
    13441 gcagggatac ttctccactt aatgttggga tcgacctatg cttggagtgt ttatcgtaat
    13501 ccaattttac aagagaccgg ttgggaccaa gctcctgtcg cttttgcctt ttctttagct
    13561 attttttgtt taggtttatc tgctgctttt atgggaaatt tagttgaaca atatggtcct
    13621 cgtctaaccg gaacggtgtc agctattctt tatgcttctg gaaatatgct gactggttta
    13681 gcgattgatc gtaaagaaat ttggctttta tatattggtt atggtgttat tggtggctta
    13741 ggacttggag cgggatatat cacaccgata tcaactatta taaaatggtt tccagataaa
    13801 agaggcatgg caacagggtt tgctattatg gggtttggtt ttgcgtcttt attaacaagt
    13861 ccgattgccc agtggctaat tgaaacagaa ggtttggtag caacatttta ccttttaggg
    13921 ctgatttatc taatagttat gctttttgct tctcaattga taataaaacc aactgctgct
    13981 gagatagcta tactagataa aaaaagatta caaaataaca gttatttaat cgaaggaatg
    14041 accgctaaag aagcacttaa aacaaaatca ttttattgtc tttgggtaat tttatttatc
    14101 aatatcacat gtggcttagg acttatctca gttgttgcgc caatggcaca agatctaact
    14161 ggtatgagtc cagaaatgtc agcaattgtg gttggtgcta tggggatttt taacggtttc
    14221 ggtcgtttag tgtgggctag tttgtcagac tatattggac gccgtgtgac agtaatactt
    14281 ttatttttag taagcataat tatgactatt agtttaatat ttgcacatag ttccctaatt
    14341 ttcatgataa gcattgccac ccttatgact tgttatggtg cgggtttttc tctcattccg
    14401 ccttatttaa gtgatctttt tggggcaaag gaactggcta cattacatgg gtatatattg
    14461 acagcttggg caatagctgc attaactgga cctatgttat tatctatcac tgttgaatgg
    14521 actcataatt atcttcttac cttatgtgtt tttattgtct tatacatttt aggattaatg
    14581 gtagcattaa ggttaaagaa atgatgtcct ataaaaaatt taaaagtaaa ccctagcaaa
    14641 gcctagggtt tttttatata attaggttta tggttaaatc atacagtaaa acagcaaatc
    14701 ataatatgcg tcgtcctgtt gtcaaagaag agcttgttca ttatatgcga acacggcaga
    14761 agcaaatcac aggtttttta gcagagttag agcaattcgc aagacaagaa aacattccta
    14821 ttattcagcc tgaggtcgtg gcttatttca ggtttttatt gcaaagctta cagccaaaac
    14881 acattttgga gattggcaca gccattggtt tttctgcgct tttaatggct gaaaatgcac
    14941 cagatgcgac gattgtgact attgatcgta atcgagagat gatcgatttt gctaaagcaa
    15001 attttgctaa gtacgacagt cgccaacaga tccgcctgtt agaaggagat gcagcagata
    15061 tattatctac acttgaagga aattttgact ttgtgtttat ggattccgcc aaatccaaat
    15121 atattgtctt tctaccagag attttaagat tgctaaaagt cggtggtgta gtcattttgg
    15181 atgatgtctt tcaaggaggt gacattacaa aatcgatcga agacattcga cgaggtcagc
    15241 gtactattta tcgtggctta cagtctttgt ttgatgccac cttaactcat ccaaacctaa
    15301 caactagcct ggtccctctt agtgatggat tattaatgat tcgtaaaaat caagcagata
    15361 ttgtattacc agattaagta acattgataa atttatgtta taataaatta gttaaagata
    15421 aaaaggagct cagaagtaaa tgaaaaactc aaataaactc attgctagtg ttgtgacatt
    15481 ggcctcagtg atggctttag cagcttgtca atcaactaat gacaatacta aggttatttc
    15541 gatgaaaggt gatacaatta gcgttagtga tttttacaat gaaacaaaaa acacagaagt
    15601 atcgcaaaaa gcgatgctaa atctggtaat tagtcgtgtt tttgaagctc agtatggtga
    15661 taaggtttca aaaaaagaag ttgaaaaggc gtatcataaa acagctgaac agtatggcgc
    15721 ttcattctct gctgctttgg cacaatcaag cttgacacct gagactttta agcgtcagat
    15781 ccgctcttca aaattagtag aacatgcggt taaagaagca gctaaaaaag aattgacaac
    15841 acaagaatat aagaaagcat atgaatctta tactccaaca atggcagtcg aaatgattac
    15901 tttagataat gaagagacag ctaaatcagt cttagaggaa ctaaaagccg aaggcgcaga
    15961 ctttacagct attgctaaag aaaaaacaac aacacctgag aaaaaagtga cctataaatt
    16021 tgattcaggc gcgacaaatg taccgactga tgtcgtaaaa gcggcttcaa gtttgaatga
    16081 gggtggcata tcagacgtta tctcggtttt agatccaact tcttatcaaa agaagtttta
    16141 cattgttaag gtgactaaaa aagcagaaaa aaaatcagat tggcaagaat ataagaaacg
    16201 tttgaaagct atcattatag ctgaaaaatc aaaagatatg aatttccaaa acaaggttat
    16261 tgcaaatgca ttggataaag ctaatgtaaa aattaaagac aaagcttttg ctaatatttt
    16321 ggcgcaatat gcaaatcttg gtcaaaaaac taaagctgca agtgaaagtt caacaaccag
    16381 cgaatcatca aaagctgcag aagagaaccc atcagaatca gagcaaacac agacatcatc
    16441 agctgaagaa ccaactgaga ctgaggctca gacgcaagag ccagctgcac aataagtagg
    16501 actttattga ctaatcagtt aaaaaaactt ataataattt agttaagaat tgtttatcaa
    16561 ggattagata cagaaaagtg acggttgctg cgagtcattg ataattagat aaacatgcta
    16621 cttaacttta caacaattga tatcgtaaat taagaatgac aagttcattg aatagaggtg
    16681 gtaccgcggt tttcgccctc tgtgagatgg acttgttttg tattgaggac tatttgaaat
    16741 caacgaaagg aatagagtag actaggctgc caggcttata gctgatctcc tagcaagaaa
    16801 gacgagctgt gtcaactggt gtgattacat tactagcttc agcataacac tgtttttctt
    16861 actctttgta tctaaatttt tatgaaagaa ttatcgtctg cacaaatccg ccaaatgtgg
    16921 ttggatttct ggaaatctaa aggacattgc gttgagcctt cagctaactt ggttcctgtg
    16981 aacgacccaa cgcttctttg gatcaactca ggagttgcaa ccttgaaaaa atattttgat
    17041 ggttcagtga ttccagaaaa tccacgtatt accaatgcac aaaaatcaat tcgtactaat
    17101 gatattgaaa atgttggtaa aacagcacgt caccatacta tgtttgaaat gcttggtaac
    17161 ttctcaattg gagactattt ccgtgatgaa gctattgagt ggggatttga actcttgaca
    17221 agtcctgaat ggtttgactt tcctaaggac aagctctaca tgacttatta cccagatgac
    17281 aaggattcgt ataaccgttg gattgcttgt ggcgttgaac caagtcactt ggtgccaatc
    17341 gaggataact tctgggaaat cggtgctggt ccttcaggtc cagatacgga gattttcttc
    17401 gaccgtggtg aagatttcga tccagaaaat atcggacttc gccttttggc tgaagatatc
    17461 gaaaacgatc gttacatcga aatctggaac atcgttctct cacaattcaa tgctgaccca
    17521 gccgtaccac gttcagaata caaagaatta ccaaacaaaa acattgatac gggtgctggt
    17581 cttgaacgtc ttgcagctgt tatgcaaggg gcaaaaacaa actttgaaac tgaccttttc
    17641 atgcctatca tccgtgaagt agagaagttg tcaggtaaaa cttacgatcc agatggcgac
    17701 aacatgagtt tcaaggttat cgctgaccac atccgtgcgc tttcatttgc tatcggtgat
    17761 ggtgcgcttc ctggaaatga aggtcgtggt tacgttcttc gtcgtcttct ccgtcgtgct
    17821 gttatgcacg gtcgtcgtct tggcatcaac gaaactttcc tttacaaatt ggttccgact
    17881 gttggacaaa tcatggaaag ctactaccca gaagtgcttg aaaaacgtga ttttatcgag
    17941 aaaatcgtta aacgtgagga agaaacattt gctcgtacta tcgatgcagg tagtggtcac
    18001 ttagattcat tgcttgcgca gcttaaggct gaaggtaagg atactcttga aggtaaagat
    18061 atcttcaaac tttatgatac ttatggattc ccggttgaat tgatagagga attggcagaa
    18121 gatgcaggct acaagattga tcacgaaggc tttaagtcag ccatgaaaga acaacaagac
    18181 cgtgcgcgtg cagctgttgt taagggtggt tcgatgggga tgcaaaatga aaccctagct
    18241 ggtattgttg aagaatcacg attcgaatac gacacatata gtcttgaatc aagtctttca
    18301 gtcatcatcg ctgataatga acgtaccgaa gctgtttcag aaggtcaagc tcttcttgtc
    18361 tttgctcaaa caccattcta tgctgaaatg ggtggacagg ttgctgacac aggtagaatc
    18421 aaaaatgata agggtgacac agttgctgag gttgttgatg ttcaaaaagc accaaatggt
    18481 caacctctac acactgtaaa cgttttagca tcactttcag ttggaacaaa ctacacactt
    18541 gaaatcaaca aagagcgtcg tttagctgtt gagaaaaacc acacagcaac tcacttgctc
    18601 catgcagccc ttcacaatgt tatcggtgaa cacgcaactc aggctggttc attgaacgaa
    18661 gaagaattct tgcgctttga ttttactcac tttgaagcag taagcaatga ggaacttcgt
    18721 cacattgaac aagaagttaa tgagcaaatt tggaacgctc ttacaatcac aacgactgaa
    18781 actgacgttg aaaccgcaaa agagatggga gcaatggcgc tttttggtga gaaatatggt
    18841 aaagtggttc gtgtggttca aattggtaat tattctgttg aactttgtgg tggaactcac
    18901 ttaaataatt cttcagaaat cggtctcttc aagattgtca aagaagaagg tattggttca
    18961 ggcactcgtc gtattattgc agttactggt agacaagctt ttgaagctta tcgtaaccaa
    19021 gaggatgccc taaaagagat cgctgctact gtaaaagctc cgcaattgaa agatgcagca
    19081 gctaaagtac aagctcttag cgactcactt cgtgatcttc aaaaagaaaa tgcagaactt
    19141 aaagaaaaag cagcagctgc agcagctggt gatgtcttta aagatgttca agaagctaaa
    19201 ggcgtgcgct tcattgctag tcaagttgat gttgcagatg caggggcact tcgtacattt
    19261 gctgataact ggaaacaaaa agactactct gatgtgcttg ttctcgtagc agctattggt
    19321 gagaaggtta atgtccttgt tgcaagcaaa accaaagatg tccacgctgg taacatgatc
    19381 aaagaattgg caccaattgt agcaggtcgt ggtggaggta aaccagacat ggctatggca
    19441 ggtggtagcg atgcaagtaa aattgcagag ctgctagcag cagttgctga aacagtgtaa
    19501 acccataaaa aaccaagtta tttagaactt ggttttttat atttgaaatg actattatca
    19561 taaccttttt gactattatc gttgtcaaaa agaaaaagat atgttacaat gatagtaaca
    19621 aatagacatg aggaggtgtt agagaaaatg acacatggta tcaaacttaa gaggcagatt
    19681 tgcttatggg caagtatcct gactcttttc attttaagtt atcatcttat cagggtaatc
    19741 tggtttggag tacccttgag ttatctggtt ttgggcttta caggactagc cttgctgttg
    19801 aatacttttt cttattttag aaagtaagtt ataagttaaa ggagaatgaa ggagatggca
    19861 atggaggtta ttcttaaaaa tcggctcaaa gaattacgag ccagagatgg aattaatcaa
    19921 acggaaatgg ctaaactggc aggagtatcg aggcagacca tcagtctcat tgagcgtaac
    19981 gagtacaccc catcagttat aattgccatg aaaattgcaa aggtatttca ggaaccagtt
    20041 gaagaggtgt ttcgtctagt ggaggtcgag gaatgaaaaa gaagaagaat agttttttac
    20101 gcttgttaaa aatgtcattg ctatcaagtt tggcgggagg gattataggt ggcatggttg
    20161 gagccttttt aggttaccat ggagggagat tagatcatct cacgttccta aaagatgatg
    20221 taattaacct gattatctta ttaaatcgtc tagtagttct cacaggcctc acactttctt
    20281 ttgttttttt aacgcaactg aaaaaagaga cagctgttta taacacagtt gaagaggatg
    20341 atatttctga aaatggttac cgtcagctga ataaaaagca tgcttatacc atgttattga
    20401 ttgccgtagc ttctatttta tccatgtgca atgtgctact tggtctgacc ttaaccaatg
    20461 attcacagca tgccatgctg gccattccgc ttctggatat ccttttatta ttaatggtca
    20521 ttccttttca agctttagcc atgaaacgtt acaatgccat tcggggaacc gatgttcctt
    20581 attttccaaa tttgaaagaa ttaaaacata atatcatggc tctagatgag gcagagttac
    20641 aagcttatca taagacatcg tttgaaagtg tgttgtcatt aaatggagtc atcatccctt
    20701 ccttgtatgt gattttattt tttgtctatc tattcactgg tcaagtggag ttaacagcca
    20761 tcttagtttt ggtgttaatt cagctctatt tactcgttaa gagtgcaaca atgaccagac
    20821 aattttaccg ttagcctaaa aggagactgt ttatgaaagg attcattaat tatttaaaaa
    20881 tagcagtgct cattattctg gctatggttt tcaatgtcct tccgatgatt ttattgcaaa
    20941 agcaacacga tattcctatg gtgcttaatt ggggaattgg tattttctac ttggttattg
    21001 ttggaagtgt ccttattgta ttatggcgtc tttatcaagc taagcaagac acccctatta
    21061 aacagcaaaa aatgagattg gttgactggg gttatttagc attattttgg ttaatcatcc
    21121 gtgtgatagc tattgtaggt acccttgtta accagctatg gtctggtcaa caaatgagtg
    21181 ctaatgatgc tgcaatacat accttagcta gacttatcaa aggtggtttc ccgctttata
    21241 ctgccctatt tgtacttgtg atagctttta tcgctcctat tatggaagaa ctagtcttta
    21301 gaggatttcc tatgattgat cttttcaaag gaaaatcact taaggtggca ggtttagtga
    21361 cctctcttgt ttttgcttta ccacatgcca ccaatagtgt tgaatttatc atgtacagct
    21421 gtatgggcat ttttctcttt gttgcctatc aaagacgagg aaacttaaaa gacgctatct
    21481 tgttacatat ttttaataac ttgattgaag tcattttgtt aatgtcaata ggcttaggag
    21541 tcatataata aaaagcttcg gatggatgaa ctgcacccca aaagttggac aaaaaaacta
    21601 acatttggtt ggacttgtca agaaaaaata gacataaagt taagctaatg agtaactatt
    21661 ttttcaaatt ctacaggtga gagataccct aaagctgaat gcagacgttt ggggttatag
    21721 taagtctcac tatatttaaa aatctcaagc tgagcttgct taatagttgc gaaatgagca
    21781 tcattgacaa gctctctttt taatgtttta taaaaggatt ccatgagtgc attatcgtat
    21841 ggattacctt ttcgactcat actggactta cattttttct gtctaagtag gtcctgaaat
    21901 catgctccgg tatattgaga accctgatct gtatggacga ttaccccttc tttaggcttt
    21961 tctctattat aagcttgatt gaaagcttct gttaccaact tgtcttgcat acatcggccc
    22021 attgcccaac caacaatctt tctactataa acgtctatca agacagacac ataaagtatt
    22081 ccttcttgtg taggaatgta ggttaagtct cctagctata atttattctt accagtcgct
    22141 tggaaacatt gattaacaag attgggacga gttaatgaag aacgtcgacg gttatagtat
    22201 ttatattgat atcgacttcc tttagcatag agacctagct gatgaaggag tctaccaaca
    22261 cgtttataat tgacatggat gccacgtcta caaagttctt gggtaattcg tacacttccg
    22321 taacgctctt tatgttcata gaaaatggct ttaatcattt ccttcaaagc ttcattctca
    22381 acatgctttg aagatagacg acgttttaaa taagcataga aacctgaacg ggagacttga
    22441 agagtttgac aggtgtgatg actattcaag ctaacactat tttccttcag aaactgaaat
    22501 cttatttccg gtttggcttc aaaaagacct ggaacttttt tagaagagct aattcctcct
    22561 gtagcagttt gtgctctttt tcaagttttt ttgtctcaaa ttgagcatga cgaagtgcgc
    22621 tcccatgtcc tgggaacgca ctttctccat attttccata ttcttgaatc catcgataaa
    22681 gactattggg atgaattttt aaagttgaac taaccatttt tacaggctgc tcttcctcaa
    22741 ggatgagttt tacagcagag agtttgaagg ctttatcaaa ggtttttctt ggcataatga
    22801 cttttcctcg ttttcactta attttgtgtc tactttagta taccaagtcc aactttgctt
    22861 aaaatataat gtccaatttt tggggtgcag ttcatccatc cgaagctttt tattaaaaaa
    22921 gtaattaact aatcatttaa ggatgaaacg ataaaactga tagctaaaat aaaaaatgag
    22981 gttagctaat gctaaaggga taatcattag taacgattgg cctgtaattt caaccagaaa
    23041 aactggtgcc gccaagggta tcttattgat cacacctaaa aagattgttg caccaaccat
    23101 aatggctaac gtgtttgata gagacaaggg aataaggtac tgactaagga tagctagtag
    23161 taagccacta gcacctccaa gcatcataga aggagcaatt ttaccccctt ttgttccaga
    23221 agcaaaaact aaagagatag cgacagcttt ggcaacaagt agccagctaa tatagctcag
    23281 atgtggttct tcatggagaa aaaagagtaa tccagctttg ccatttccta aaatctctgg
    23341 gaagaaaatg ctgagtcctg cgataaggct aaaagcgatg agaactttcg gaataaacca
    23401 ctgacttttg gcatcagcct taggaaggtg ttccagaaga tgtttgtaag cgtgagcaaa
    23461 gagggaaagg ataagaccag ccaggacgga ccaaataagg gttcctagcg tccaatgttg
    23521 ctgaggcatt aggtattgaa tctcatgtcg gccttgtaat aaagcaactg tttccacagc
    23581 cacatagctc gttaggcagg cagcgtatat atttttaagg gaccaacggt taagaatagc
    23641 ttctaagata aataaaatag tggctaaggg agcattgtag acagcaccaa gggcagcgcc
    23701 agaagcgcag gctaataaaa gtttttgatc ggcttttgac aagttgcatc tttggctcca
    23761 aagagacgtc aaggtaacag cgacttcccg tgaagctcct tctcggccga caggagctcc
    23821 catagatacg gtcgttaatt ggagccaacc atgccaaaac tgtgtccagg gactaaatga
    23881 gatgtcatct tgaatgattt gctgaataga ttgaatgtcc tttccttttt tagccaatag
    23941 gtgccaccca agacctgcaa gaagtccagc aaagaggagt gaaagagctc gtctttgtgg
    24001 tggaacacta gcaatcatag tgctaaaaga accttgactg aatccaaaac tgagggactg
    24061 aatcaggtga atggcttttg ttaagataaa agcaacaagg ccagctgtta aacctgttaa
    24121 aaagaggtaa aaggtcaaga gtaaaaagtg tcgtttcata agactattat aacaaaagtt
    24181 aagaaaagag actgatagat tatcagtctc ttgagcacta ttagagtcca taattataat
    24241 cgtcatcaga catagcttct acagaaccaa gaagatagcc attccctacc tgtgagaaaa
    24301 agtcatggtt tgatgttcct gttgaaatac cattcataac aattgggtta acatcgtttg
    24361 cagtatctgg gaataaagga tcttgtccta aattcataag agctttgtta gcattgtagc
    24421 gtaaaaaggt cataacttct tcagtccacc ctacgccatc ataaagcgtt ttggtgtatt
    24481 tttcttcatt ttcatacagc tgataaagga ggtcatacat ccaatcacga aaattctctt
    24541 gctcatcttc tggtagttcg ttaaaaccaa gctggaattt gtaaccgata taagtaccat
    24601 gtacagattc atcacgaata attagtttaa tgatttcagc aacatttgct agcttattat
    24661 ttcccaaata gtaaagaggg gtgaaaaagc cagaataaaa aaggaaagtt tcgagatatg
    24721 ttgaggcaac tttcttttgt aaggcatctc cattagcgta aatgttattg ataatacgtg
    24781 ctttttcttg aagaaactca ttattattag tccactcaaa gatctcttca atttcttttt
    24841 tggtgtttaa ggttgaaaag atggacgagt atgatttagc gtgaacagat tccatgaatt
    24901 gaatattgtt taagacagct tcttcgtgag gagtgcgaac atcagcacga atagcttcga
    24961 caccagtttc tgattgcatg gtatcaagta gggttaatcc tccaaaaacc ttgccaacaa
    25021 gatctttttc ttgaagagaa agtttgcgcc aatcgtctaa gtcatttgat aaagggatac
    25081 gggtatcaag ccaaaattgt tcggtcaact tttcccaagt tgacttgtca atgacgtctt
    25141 cgatttcatt ccagttaatt gcttcataat atgtagtcat agaaaaatga tctcctaaag
    25201 agtagtaaag tgcgttaagg atatcgagat aaaccagtag aaccgaccaa agttctaccg
    25261 gtaataataa gtttaaatag attcaaaagg gtaacgaatg agttagtgag tggtttaggc
    25321 agatcgccta aagcgactgc cgtagaagta atagatgctt tagcatcatt acttcttaac
    25381 caattaaatg acacaagatt cacattggtt tgcgcccact tcttccccat catccgtaaa
    25441 ggtacggata tagtagatag atttaatgcc tttattgaaa gcgtagtttc gtaagatgga
    25501 taaatcacga gtggtttgtt tgctttgtgt tttccactca taaagctcca taggcaactc
    25561 actacgaagg aatagagtta atgacaagcc ttggtccaca tgttcggtcg cagcggcata
    25621 gacatcaata actttgcgca tgtccatatc gtaagcagat gtatagtaag gaatggtatc
    25681 cgtagacaaa ccatttgcag gatagtagat tttaccaatt ttcttttctt gacgctcttc
    25741 gatgcgttgt gtgattgggt gaatagaagc agagcagtca ttgatataag aaatagagcc
    25801 atttggagca actgctagtc ggttttgatg ataaagacca tctttttgaa cggcgtcgcg
    25861 aagagcctcc caatctgaag cttgcggaat aaaatggtct ttaaagagac ttttgaccaa
    25921 atcagatttt ggaacaaagt gtcctgtaac gtatttatca aagtaactac catcagcgta
    25981 cttagagttc tcaaagccaa caaaggtagt ttggcgctca cgagcgatgt tattggattc
    26041 gaccaaggtc caataattca ggagcataaa gtaaatatca gtaaactcga tggattctgg
    26101 actgccatat tcaatatgat gttgagcaag gtaagaatgt agtcccatag ctccaaggcc
    26161 aaaagtatgt gcttgactgt taccatgttt aatggttgga acagcttcaa tgcttgatga
    26221 atcagtaaca aaagttaggg cacgtgtcat ggtcttaata gaacggccaa agtctggtga
    26281 ggtcatcatg ttcaggatat tagtggaacc taagttacat gaaatatcag ttcccatttc
    26341 tacaaactct tgcgtatcat tgataaggct aggtgtttga acttgtaaaa tttcagaaca
    26401 caagttgctc atgatgattt ttccatcgat aggattagct ttattagctg tatcaatatt
    26461 gatgatataa gggtaaccag attcttgttg taattttgaa atctctgttt caagatcacg
    26521 agctttaatt ttagtcttag taattttagg gttcgccact aactcatcgt acatattggt
    26581 aatgtcgaga tagttaaagg gaatgccata ttctttttca acattgtaag gactaaagag
    26641 atacatgtcc tcgtttttac gagctaattc gtagaattta tcaggaacgg taatccctag
    26701 tgacaaggtt ttaacacgca ccttttcatc ggcattttct tttttagtag ataagaaagc
    26761 aatgatatca ggatgaaaaa catttaggta aacaacacca gctccttgac gttgcccaag
    26821 ttgatttgaa taagaaaaac tatcttcaaa taatttcata acaggaacaa ctcctgaggc
    26881 tgcaccagca tagcctttga ttggtgcgcc agcttcacgg aggttagaca aggtaatccc
    26941 aacacctcca ccaatacggg ataattgcaa ggcagagtta atggaacgtc cgatagaatt
    27001 catgtcatca gttacttgaa tcaagaaaca agagaccaat tcaccacgac ggcttcgacc
    27061 agcatttaaa aaggaaggag tagccggttg gtaacgttgg ttaatcattt caacggctaa
    27121 atcttttgct aagtcttctt gaccatctgc aaaatacaaa gcattaaaca agacacggtc
    27181 ttcaaggttt tctaaataat gctctccatc atttgttttt aaggcgtatt gctggtagaa
    27241 cttgtaggct gccataaatg atttaaagcg aaaattttct gatttgatta tgccagctaa
    27301 ttcagtaata aattcagggt ggtatttctg aataaaagct gattcaatgt aatcatttga
    27361 gattaaatac tcaatttttt ccgtaatgga agtaaaagac atggtgtttg gcagcacatt
    27421 ttcagcgaaa aaagctttta aagcttcttt gtctttatga agtggaattt taccattaac
    27481 aggacggtta atttcattat ttaggcgaaa atatgaaata tcgccaagat ctttgagact
    27541 catattattt ttccttgtct tattaaatca attcttttaa ctttgcaggt tggaagccag
    27601 aaaatacgag gttatctgct tcgataacag gagcagatgt gaagccaaga cttttcacat
    27661 aatccacttt ttcaggatgt tcatcgatat taatttcctg gaagttggct ccgtgttgtt
    27721 ctaaaaattt cttagtcatt ttgcactgca tgcaattatt tttggaatat actgtaatca
    27781 tgtcttgtcc ttctaaaatt agtaatggtt ccatcttaaa tggaattact ataatagcat
    27841 ataaaaaata aagctaaaaa gcaagctata aacttatcta aaacacaaca tattgtgttg
    27901 aaataaaaaa cagaaaccta aatattgtgt caatctggat tcttatggtt agagctctag
    27961 cgttttggtg atagaagcta agcagtttta ataaagcatt aaagtttgaa aaataaattg
    28021 tgaaaaacgt gaaaataaaa gaaaataatt tcacattttt tgtcgtttaa atatttaatc
    28081 ttgaaaataa aaaagcattg tgctataatc ggttgttgta agggttatca tgtgatggct
    28141 caaaaataca caacttaaaa ggagaaccat actatggctt caaaagactt tcacattgtt
    28201 gcagaaacag gtattcatgc gcgtccagcg actttgcttg ttcaaacagc tagcaaattt
    28261 gcttcagaca tcactcttga ctacaaaggt aaagcagtaa atctaaaatc aatcatgggt
    28321 gttatgagtc ttggtgttgg tcaaggtgca gatgttacta tctcagctga aggtgcagat
    28381 gctgaagatg ccattgcagc aattgaagaa acaatgacta aagagggatt ggcataagac
    28441 tatgacagaa atgcttaaag gaattgcagc ctcagacggc gttgctgttg ctaaagcata
    28501 tctactagtt cagccggatt tgtcatttga gactgttaca gtcgcagata caaatgcaga
    28561 agaagctcgc cttgatgttg cactccaagc tgcacaagac gagctttctg ttatccgtga
    28621 aaatgcagta gaaagcttag gtgaagaagc agcagccgtt tttgatgccc atttgatggt
    28681 tcttgctgat ccagaaatga tcagccaggt taaagaaacg attcgcgcaa aacaaacgaa
    28741 tgcagaaaca ggtcttaaag aagtgactga catgttcatc accatctttg aaggcatgga
    28801 agataaccca tacatgcaag aacgcgcagc ggacatccgc gacgttgcaa aacgtgtgtt
    28861 ggctcacctt ttaggtgtaa aacttccaaa tccagctaca atcaatgaag aatcaatcgt
    28921 tatcgcacac gatttgacac cttcagatac tgctcaactt aacaaacaat ttgtaaaagc
    28981 atttgttaca aatatcggtg gtcgtacaag tcactcagct atcatggcac gtacacttga
    29041 gatcgctgcg gtacttggaa caaatgatat tacaaaacgt gttaaagatg gtgatgtgat
    29101 tgccgttaat ggtatcactg gtgaagtgat tatcgatcca agcgaggatc aagtacttgc
    29161 ttttaaagaa gctggtgcgg cttatgccaa acaaaaagca gagtggtctc tccttaaaga
    29221 tgcgcatact gaaacagctg atggcaaaca ctttgaattg gctgctaata tcggtacgcc
    29281 taaagatgtt gaaggtgtta atgacaatgg tgctgaagct gttggccttt accgtactga
    29341 gttcttgtac atggattctc aagacttccc aactgaagac gaacaatacg aagcttacaa
    29401 ggcagtgctt gaaggcatga atggcaaacc tgttgtggtt cgtacaatgg atattggtgg
    29461 agataaggaa cttccttact ttgaccttcc aaaagaaatg aacccattcc tcggtttccg
    29521 tgctcttcgt atctcaatct ctgaaactgg ggatgccatg ttccgcacac aaatgcgtgc
    29581 gcttcttcgt gcctctgttc acggacaact tcgtatcatg ttcccaatgg tagcacttct
    29641 taaagaattc cgtgctgcaa aagcagtctt tgacgaagaa aaagcaaact tgcttgcaga
    29701 aggcgttgcg gttgctgatg acatccaagt tggtatcatg attgagattc ctgcagctgc
    29761 tatgcttgca gaccaatttg ctaaggaagt tgatttcttc tcaattggaa caaacgacct
    29821 tatccaatac actatggcag cagaccgtat gaacgaacaa gtatcatacc tttaccaacc
    29881 atacaaccca tcaatattac gtttgatcaa caatgtgatc aaagcagcgc acgctgaagg
    29941 taaatgggca ggtatgtgtg gtgagatggc aggtgaccaa caagctgttc cacttcttgt
    30001 cggaatgggc ttggatgagt tttctatgtc agcaacttca gtacttcgta cgcgtagttt
    30061 aatgaagaaa cttgactctg ctaagatgga agaatatgca aatcgtgcgc ttacagaatg
    30121 ttcaacagca gaagaagttc ttgaactttc taaagaatac gtttctgaag attaaagggt
    30181 taaagagttg gtttaaacca gctctttttt gctagctaaa aatacaattg ctttttggtg
    30241 tgaaatcatt tgagtcatca aataattatc agagttttca gatatttagt gtagctaaat
    30301 cttgaattat atcggaaaag tgatagaata agattactac cataaaagga gataaaacgt
    30361 tggcaaaaca atataaaaat ttagtgaacg gtgaatggaa actatcagaa aacgagatta
    30421 ccatttacgc accagcaaca ggtgaagagt taggatcagt tccagcgatg acgcaggcag
    30481 aggtagatgc tgtttacgct tcagctaaaa aggctctatc agattggcgc gctttgtctt
    30541 atgtggaacg tgcagcttac cttcataaag cggctgatat tttagtacgt gatgctgaaa
    30601 agatcggcgc gattctttca aaagaagtag ccaaaggtca taaggcagct gtcagtgaag
    30661 ttattcgtac cgctgaaatc attaattatg cagcagaaga agggcttcgt atggaaggtg
    30721 aagttcttga aggtggtagc ttcgaagccg caagtaagaa gaagattgct attgttcgtc
    30781 gtgaaccagt tggtttagtt cttgccatct caccttttaa ttatcccgtt aacttggcag
    30841 gttctaaaat tgctccagct cttattgcag gaaatgttgt tgctcttaaa ccaccaacac
    30901 aaggctctat ttctggtttg ttactagcag aagcttttgc agaagctggt attccagcag
    30961 gtgtctttaa taccattaca gggcgaggtt ctgttatcgg tgattacatc gttgagcatg
    31021 aagcggttaa ctttatcaac tttacaggtt ctactccaat tggggaagga atcggtaaat
    31081 tagcgggtat gcgaccaatt atgcttgagc ttggcggtaa ggattctgct atcgttttgg
    31141 aagatgcaga tcttgcttta gcagcgaaaa ttattgtagc cggtgctttt ggttactcag
    31201 gacaacgttg tacagcggtt aaacgcgttc ttgtgatgga caaggtggcg gatcaattgg
    31261 cggctgagat taaaaccctt gttgaaaaac taagtgtcgg aatgcctgaa gacgatgctg
    31321 atattacacc attaattgat acatcagctg ctgattttgt tgaagggttg attaaagatg
    31381 caactgataa gggagctact gctttgacag cctttaatcg tgaaggcaat cttatttcac
    31441 ccgttctctt tgatcatgtg acaactgaca tgcgtttggc atgggaagag ccgttcggcc
    31501 cagtattacc aattattcgt gtaaccactg tagaagaagc catcaagatt tctaatgagt
    31561 ctgaatatgg tttgcaagct tctattttta caactaattt cccaaaagct tttggcattg
    31621 ctgagcaatt agaagttgga actgttcacc ttaacaataa aacacaacgt ggaacagata
    31681 atttcccatt cttaggcgct aaaaaatcag gtgcaggggt acaaggagtt aaatattcta
    31741 tcgaagctat gacaactgtt aaatctgttg tatttgatat ccagtaataa aaaaaataaa
    31801 caaaaagtta ggttaactta actttttgtt tattttttta atgttttttg ttacaatagt
    31861 ctatacagat ggaggcaact attgaaaaaa ttaaatgtta ttcttgttgg tttattaagc
    31921 attctgatgt tgagtttagc tattgtgttt attaatcgtt ggaaactaaa cgaagatagt
    31981 cagcgtatag ttttggctga aaagaaaaaa aacacgtcag atttagtgat caaagctgta
    32041 aaacatatta aaaaagatca aaaagactat tattattttt ccccgataaa acaagcagat
    32101 gatttttttg tagataattt acctgtttca ttatacaaaa aaaagaattc agataaagaa
    32161 ttgattttag taaagcctaa actgcaatct tctcacctaa gatcagttaa cactttgact
    32221 atttctaaaa tagtttatca gaaaaaattt tttcatttgg ctaaaaaatc agaaaaagtt
    32281 ataagtacat atcacgttac agacgacttg aaaccgtttc aggtaaagga tctagtatca
    32341 ggacatttag aaagaataca agaagaaatt gaaaaaaaat atccaaatgc tggttttaat
    32401 agcgataagt ataatggctt aaaagaatct aattctttat taagcgatgg ctttgaggta
    32461 aaatcgggaa accttatttt tgataaaaag ctaacgatac ctttgacgac attatttgat
    32521 gttattaatc cagatttttt agcaaatagc gatagagctg cgtatgataa ttataggacc
    32581 tacaaagaac agcatcccaa aaaactagtt gcattaacgt ttgatgatgg tccagatccg
    32641 acgacgactc ctcaagtttt agatattttg gcaaaatacc aggctaaggg aactttcttt
    32701 atgataggtt caaaagttgt ggataatgaa aaccttacta agcgtgttag cgacgctggc
    32761 catgaaattg ctaatcatac ttgggatcat cccaatctga ctaatctttc agtcagcgag
    32821 attcaacatc aagttaatat gacgaaccag gctattgaaa aagcttgtgg caagaaacct
    32881 cgctatttac gccctccata cggagctaca aatgcaactg ttcagcaatc ctcaggatta
    32941 acacaaatgc tttggacggt tgatacaaga gattgggaaa atcatagcac tgatggcatt
    33001 atgactaatg tcaaaaacca attgcaaccg ggaggagttg ttttaatgca tgatattcat
    33061 caaacaacta tcaatgcttt gccgacagtt atggaatatc taaaagcaga aggatacgaa
    33121 tgtgtgactg tatcagaact ctatgcgcat cagtaagtaa tatcgttatg tttctttaga
    33181 attgatatac taaacaatcc aattactttt gaagtaattg gattgttgtt tttagtagcc
    33241 cttgattaag ttttgttttt taacaactag ttgatgaaat gaagttgttg atttttgagg
    33301 gagatttcag agactttagc aaattttttc aattttttga ggtcttcagg gtggctaaca
    33361 aaggtaataa cgataccaga ttttcccata cggccggttc gtccagctct gtgagtataa
    33421 ttttccttat cacgagcaac atcaaaatga atgacatagt caagattatc aatatcaatg
    33481 ccccgagcaa caagatccgt agctaacaat aaggaaagtt ggtgggattt gaatttttcg
    33541 agaatggttt tacggaattt gacattgatg tcactcgcta aggaaaccgc agcagctcca
    33601 ttatattgga gacgttcttc cgtagcaccc aaatcagata aactgttgaa aaagaccaaa
    33661 gctctaaaat gaggaatatt agcaaatttt cgtaataaat ctgtacgttc gcgcttgtca
    33721 accatgaggt aaaaatgctg aatagcatcg ttggtttgct ctgaaagatc gatgcagaat
    33781 gtatttggag ctaaggaagt ttgatccacc ttattagtag cactcatgta taccatttga
    33841 tgatctcgag gaacatagtg gctaattttt tgaacaaaat catattggga atcacctaat
    33901 agttcgtcat attcatctaa aacaatggtg ttgacagaca tcatcttgat ttttttcaat
    33961 ttaatcagct caaaaatgcg tccaggggtt ccaatcagaa tttcaggacc ttttttgagg
    34021 cgttcgattt gacgtttttg actggttcca gaaataaaga gttgtgccgt taagcctagt
    34081 gactgtgccc aatcctttgt gacttcaaaa atttggccag ctaattcggt attaggggct
    34141 aaaatgagta gttgttggga ctttttaggc gtcagtgcca atagactagg aaagacataa
    34201 gctaaggtct tgcccgtccc agtagggcta ataccaagga aatttttacc atcaacaata
    34261 ggttgaaagg cctgttcttg gattggcgtt aaatgggtaa atgcaacttg gtcaagtttt
    34321 tcttgccatt gagggggaaa tttagtgatc atgcgtcttc cttttactat tgtttctata
    34381 ttcattatag cattatagtc tcaattttgg taaaatagtg agaaagactt tttagatttg
    34441 gagtttaaaa tgcttaaaaa accgattatt attggtgtaa ctggtggttc aggtggcggt
    34501 aaaacaagtg tgtcacgcgc tattttggac agttttccaa atgctcgtat tgcaatgatt
    34561 caacacgatt cttactataa agatcagtct cacatgagtt ttgaagaaag ggtcaagacc
    34621 aattatgacc atcctctagc ttttgataca gattttatga ttcagcaact aaaagaatta
    34681 ttagctggta gacctgtaga tattcctatc tatgattaca aaaagcatac ccgcagtaat
    34741 acgacctttc gtcaggatcc tcaggatgtt attattgttg aaggtattct tgtcctagaa
    34801 gatgagcgtt tgcgagattt gatggatatc aagctctttg tagacacaga tgacgatatt
    34861 cgtattattc gtcgtattaa gcgtgacatg atggaacgtg gcagaagctt agaaagtatt
    34921 attgatcagt acacaagcgt ggtaaagcct atgtatcatc agtttattga gccaagtaaa
    34981 cgctatgctg atattgttat tccagaggga gttagtaatg tcgttgctat tgatgttatt
    35041 aatagtaaaa ttgcgagtat tcttggagaa gtatagtgga agtggctgag tagattattt
    35101 aaatctgctc ttttattgtt gtgctcttcc tagagaaagg gatcataaaa tagaaatgtt
    35161 attaatttgg cttggattac tatttgtttg gaatgaactc gtgtttgtca tatatgcctt
    35221 tgataaaaga aaagccataa aaaagaaacg gcgtattagt gaaagaaact tattagtgat
    35281 aacaattttg tttggaggtt ttggagcatt acttgcagct aaaaagtacc accataaaac
    35341 cagaaagtgg tactttgtca tcacttggta tactagtatt ttgttgacat tactagtaac
    35401 ttatatcttt atgaagtgag tcacttaaaa gacccttaat cagtattatt tagtcagggc
    35461 tcttttatag tttaaaaaag cacatcatcg tcaagggtgt tgattttttg aaaaagatca
    35521 ccaaagatta aaaggattaa tgttcctagt aaaactgtca taccaggaat gcttgttaga
    35581 ggagagttcc agatgaaatg tagaaccaga ggacttaata accagaaaat ttgttgctgt
    35641 tttgaaaaaa ggttagaacc ctttaataat aagtatgctc caatggtaaa aatagctgta
    35701 tgtacccaat gtgaagtcac agcagtgcta atacgttcaa tagcagtcgg tacgagacta
    35761 tctatagatt ttgcttgaat caaataacgg atatcttctg ttagttgaaa gcccatgcca
    35821 gaaagtaaag caacaactaa tttttcttta agagtaagtc taggaaataa agtaattact
    35881 aaaatagccg aagaagcctt aatgggctct tcgacaatag gggcagttaa agcatctccc
    35941 caaagcttta aagcgtcttt agaagggatg atgtatgacc aaaattgtcc tacgagatgg
    36001 ttcccacaag aagctaaaaa acctgaaata taaagtccgc taagacagct aacaataata
    36061 acgttcaggt tcatatgaaa ttttttactt aaataaaaaa tagctgctgc aaatggaatt
    36121 aagtaaatgc ctaatagact aatggttagt attagagcaa aagcttcttt aaaggaaagg
    36181 ttgttagcag tcagtcctaa caattcaagt tcaataccat ttaaaactaa agcaataaaa
    36241 agaccgtatc gtaaccattt ctgttgagtg atttgtttca cgaaaacctc ctaatattaa
    36301 gatgatatta ataatattga aaattatatc ataaacaacc tcaaaaacca ttttaaaaac
    36361 tgactgaagc gaaagatagt cgtaaaaaat actcgaatag acccagatat gctataataa
    36421 aaggtatgaa taagtctaaa aaaattgagc aataccaact aatgatagcg caggcaaaag
    36481 agctgtttgc gaatgaatca aatgctttgg ctaatttgtc aaatgccagc gccctgttaa
    36541 acatgacact acccaattct gtttttacgg gattttacct ttttgatggg caggaattaa
    36601 ttcttggccc ttttcaaggt agggtttctt gcgtccatat caagcttggt aaaggtgttt
    36661 gtggcgaatc agctcagtct cgtcgaacca ttattataaa tgatgtgaag cagcatgcca
    36721 actatatttc ctgtgatgcg gcagccatga gtgaaattgt tgtgcctatg gtgaaagaag
    36781 gccatttgat tggggtgctg gatttggatt ctagtcttgt agctgattat gatgaggttg
    36841 atcaagaata cttagagacc tttgtggacc tacttcttga aaagaccacg tttaccttta
    36901 acatgtttgg agttaaaaac tgatgtatca agctctttat cggaaatacc ggagccaaac
    36961 gtttgacgaa atggtgggac aatcggttat ttccacaact ttaaagcagg cagttgaatc
    37021 tggcaagatt agccatgctt atcttttttc aggtcctaga gggactggga aaacaagtgc
    37081 ggcaaagatt tttgcaaagg ccatgaattg tcctaaccaa gtcgatggtg aaccctgtaa
    37141 tcaatgcgat atttgccgag atatcacgaa tggaagcttg gaagatgtga ttgaaattga
    37201 tgctgcctcg aataatggtg ttgatgaaat tcgtgacatt cgagacaaat caacctatgc
    37261 gccaagtcgt gcgacttaca aggtttatat tattgatgag gttcacatgt tatcaacagg
    37321 ggcttttaat gcgcttttga aaactttgga agaaccgaca gaaaatgttg tctttatctt
    37381 ggcaacaacg gaattgcata aaattccagc cactatttta tctcgtgtgc aacgctttga
    37441 attcaaagct attaagcaaa aagctattcg agagcattta gcctgggttt tggacaaaga
    37501 aggtattgcc tatgaggtgg atgctttaaa tctcattgca aggcgagcag aaggaggcat
    37561 gcgtgatgct ttatctattt tagatcaggc tttgagcttg tcaccagata atcaggtcac
    37621 cattgcaatt gccgaagaaa ttacaggttc tatttccata cttgctctag gtgactatgt
    37681 tcgatatgtc tcccaagaac aggctacgca agctctggca gccttagaga ccatttatga
    37741 tagtgggaag agcatgagcc gctttgcgac agatttattg acctatctgc gtgatttatt
    37801 ggtggttaaa gctggcggcg acaatcagcg tcagtcagct gtttttgata ctaatttgtc
    37861 tctctcgata gatcgtatat tccaaatgat aacagttgtt actagtcatc tccctgaaat
    37921 caaaaaggga acccatcctc ggatttatgc cgaaatgatg accatccaat tagctcagaa
    37981 agagcagatt ttgtcccaag caaatttgtc aggagagtta atctcagaga ttgaaacgct
    38041 caaaaatgag ttggcacaac ttaaacaaca attgtcgcag ctccaatcgc gtcctgattc
    38101 actggcaaga tctgataaaa cgaaacctaa aactacaagc tacagggttg atcgggttac
    38161 cattttgaaa atcatggaag aaacggttcg aaatagccaa caatctcgac aatatctaga
    38221 tgctctaaaa aatgcttgga atgaaattct agataacatt tctgcccaag acagagcctt
    38281 attgatgggc tctgagcctg tcttagcaaa tagtgagaat gcgattttgg ctttcgaggc
    38341 tgcctttaat gcagaacaag tcatgagccg aaataatctt aatgatatgt ttggtaacat
    38401 tatgagtaaa gctgctggtt tttctcccaa tattctggca gtaccaagga cagattttca
    38461 gcatattcgt aaggaatttg ctcagcaaat gaaatcgcaa aaagacagtg ttcaagaaga
    38521 acaagaagta gcgcttgata ttccagaagg gtttgatttt ttgctcgata aaataaatac
    38581 tattgacgac taaaactgaa atacataagg gtaaggtttt gcccttaccc acgttttatc
    38641 tcgttacttt ttttcatagt acagtatttt tttgttataa taaagctatg actattcgac
    38701 aatttctttt tatggccttt gtatgtgcct ttgaaaccta tttttttaat gacctgttgc
    38761 tctctggaaa ttatctcttc gccttatttt ggggcttgtt gctctttagg gatttaagaa
    38821 gagtgcatac cattaaccaa ttgactaaaa ccattttaaa agcggctaat tctcccaaga
    38881 agaaagactg atttcaccgc ttcgcaaggt ttgaaggtca ccattgtcaa attggacaat
    38941 aaggtgtcct tgatctgtga gatcaatcgc aatagcacgt ttttcttgac tattttctat
    39001 aaaggtcact tgtttattaa gaacaagtga tttttctttg taaactttga catggtcctt
    39061 gacaggaata gataagaata atttccagat gtcaatgata aggtcattgc gcgtgatagt
    39121 cggtttttcg gtaaagagag aacctgcctt ttgagcaatc gcttctggga agtcggtgac
    39181 aaaaaagttg agaccaaccc caataatgac atcggtgatt aaaccagttt caacagaagt
    39241 aatggcttct gtcagaatcc ctgcaacttt atggttacct agatagatgt cgtttaccca
    39301 tttgatttct gtatcaatgc ctgttaatcg cgagatagct ttgacaatac tggaagcaac
    39361 catcatcgta taaggaggca tatcagcata agggacattg ggttttaggt acatggacat
    39421 gtaaatacca ccggtgctag ctgaaaaaaa ttgccgatcg aggcgtcctt tggcagcttc
    39481 ttggctagga gctaggtaaa gccttggagc gctgttatga gcttcgattc cttgtttggc
    39541 atctaattgg gtagattggc tgtgaggggt ataggtgact ggcatcccaa gcccttggct
    39601 aatggttttg ggtaataaaa tatcaccttg taccatgcgg tagcccttgt gttttaaaga
    39661 atcaatttga atcccctgat tttcgagact tttgatggat ttccaaacgg atgtacgaga
    39721 gatactgagt tgatctgcta gatattcccc actgacgaag tcatcggttt gtgacagtaa
    39781 ttgataaatt ttttctgatg ttttcatatg tatagtatat tataaaagat cttattttca
    39841 aaggaaaaga aaagttagtt ttttgtgtaa tgctactaac aacagaaact attgtttgtt
    39901 gaagcttcag agctccaact cgtcaacaat taatagttat cctaaaaaga gcttgaggaa
    39961 aaacaagtga tgtgatatac ttaactggtt aaataaaaag gagggttgaa tgaaaacgaa
    40021 aaaagttatt attttagttg gtctattgtt atcatctcag ttgactttga tatcttgtca
    40081 atcacgaggt aatggtacat atcccattaa aacgaaacaa tcacgtaagg gaatgacgtc
    40141 aaacaaaatt aaaccgatta aaaaaagcaa aaagacaaac aagactcaca aaggtgtggc
    40201 gggtgtcgat tttcctacag atgatgggtt tattttaacc aaagactcaa aaatcttatc
    40261 aaaaacagat cagggaatcg ttgttgacca tgatggtcat tcgcatttta ttttttatgc
    40321 cgatttaaag ggaagtctat ttgaatacct tattccaaaa ggagcaagtt tagctaagcc
    40381 agctgttgct cagcaagcag ctagtcaagg gacttctaaa gtagcagatc ctcatcacca
    40441 ttatgaattt aacccagcgg atattgtggc tgaagatgct ttaggctaca cgattcgcca
    40501 cgatgatcac ttccattata ttttgaagtc aagcttatca ggtcagacac aggcacaagc
    40561 taaacaggtt gctactcgct tgccacaaac cagtagccct gtttcaacag ctacagctaa
    40621 tggtattcca ggcttgcatt tcccaacctc agatggtttt caatttaacg gtcaaggtat
    40681 tgttggggta acaaaagaca gtattttagt ggaccacgat ggtcacttac atcctatttc
    40741 ttttgcggac cttcgtcagg gtggctgggc acatgtggca gatcaatacg atcccgctaa
    40801 aaaagcagaa aagccagcag aaacccatca cacaccagag ctatctgaac gtgaaaagga
    40861 ataccaagaa aaattagctt atttggcaga aaaattgggg attgatccat caactattaa
    40921 acgtgtggaa acacaagacg gtaaacttgg tttggaatac cctcaccatg accacgcaca
    40981 cgtattgatg ttatctgata ttgaaatcgg aaaagacatt ccagatccac atgctattga
    41041 gcatgcccgt gaattggaaa aacataaggt tggaatggat accttgcgtg ccttagggtt
    41101 tgatgaagaa gtgattttgg atatcgttcg cactcatgat gctccaaccc cattcccatc
    41161 aaatgaaaaa gatccgaata agatgaaaga ctggttagca acggttatca aacttgactt
    41221 gggcagccgt aaagatcctt tgcaacgtaa aggactttca ctgttaccca acttagaaat
    41281 tttaggactt ggctttacac caatcaaaga tatctcacct gttttgcaat ttaaaaaatt
    41341 gaaacagttg ttaatgacaa aaacaggggt gactgattat agatttttgg ataatatgcc
    41401 acagttagaa ggcattgata tttcacaaaa caatctcaaa gatattagtt tcttgagcaa
    41461 atataaaaac ttaactctag tagcggctgc tgataatagt attgaagata ttaagccgct
    41521 tggtcaatta ccaaatctca aattcctcgt attgagtaat aataagattt ctgatttaag
    41581 cccactggca tcgttacatc aattgcaaga attgcacatt gataataatc agattacaga
    41641 tttaagccct gtttctcata aagaatcatt gacggttgtt gatttatcaa gaaatgctga
    41701 tgttgactta gcaacacttc aagcacccaa attagaaacg ttaatggtca atgataccaa
    41761 ggtttctcat ttggatttct tgaaaaataa tcctaatcta tctagcctat ctattaaccg
    41821 tgcgcaattg caatctcttg aaggtattga agcaagtagc gtcattgtca gagtagaagc
    41881 agaaggtaac caaattaaat cgcttgtgct taaagacaag caagggtcac ttactttctt
    41941 ggatgtgaca ggcaaccagt tgacttctct agaaggtgtt aataatttta cagcacttga
    42001 cattttaagc gtgtctaaaa accaattaac aaatgtcaac ctatctaaac ccaataagac
    42061 agttactaac attgatatta gtcataacaa tatcccattg gcagacctta aattgaacga
    42121 gcaacatatt ccagaagcca ttgcgaaaaa cttcccagcg gtttacgaag gttctatggt
    42181 aggtaatgga acagctgaag aaaaagcagc tatggctact aaggcgaaag aaagtgctca
    42241 agaagcaccg gaatcacatg actacaacca taatcatacc tatgaagatg aagaaggtca
    42301 tgctcacgag cacagagaca aagatgatca cgactatgaa catgaagatg aaaatgaagc
    42361 taaagatgag caaaaccatg ctgattaaac taatctaaga ataaccctat ccaactgaat
    42421 cgtcctaatg acaccattgt tgactatcaa gaaaacctca agaataacct tgaggttttt
    42481 ttgaaataaa taagataatg ggtgaaaaga atggcaccta aatggctaaa acatgttata
    42541 atagattgtt attgagtccc gataagacgg tctgtcgaac gaaatgtttt tgagacgttg
    42601 ttgactttat ttggggaaca gtcgttctcc ctttagctaa attacttcgt ctaaggctta
    42661 ttttgtggtg acatcctctc aacaaggaga ccggattctt tgtaactcaa cgctattgtc
    42721 agacattctt tgtctggtta atggacgcta gccactaggt ggactagcta gttgccttac
    42781 tagtaaaacc gtaactgatt agctaagttg gttttggcca cttgacttgc tcaatcagct
    42841 aggaagaaag gggtaggcaa cttcttgctt tgtggtcaat gtgactgaaa aaggaagaat
    42901 caacatatta ggggggacat ttttatgtca gaacgtaaac ttttcacgtc tgagtccgta
    42961 tctgaagggc atccagataa gattgcagac caaatttcag atgctatttt agatgccatt
    43021 ttagcagaag atccagaagc ccatgtggct gcagaaactt gtgtttacac aggttctgtt
    43081 catgtttttg gagaaatctc aacaacagca tacattgata ttaaccgtgt ggtccgcgac
    43141 accattgcag aaattggtta tacagaagca gaatatggct tttcagcaga atcagtggga
    43201 gtacatccat cacttgtaga acaatctgga gatatcgctc agggggttaa tgaagctctc
    43261 gaaagcagag aaggtgatac tgatgacctt agccatattg gagcgggtga ccaagggctc
    43321 atgtttggtt ttgccatcaa tgaaacacca gaattgatgc ctttaccaat ttccttatct
    43381 caccaattag tgcgtcgctt ggcggaatta cgtaagtcag gtgagattag ttatctacgt
    43441 ccagatgcta aatctcaagt gacagttgag tacgatgaac acgataaacc tgttcgtgtg
    43501 gatacagtcg ttatttctac tcagcatgat ccagaagcta ctaataacca aattcgtcag
    43561 gatgtgattg aaaaagtgat caaggctgta attccagcag attatttaga tgatgacaca
    43621 aagttcttca ttaatccaac aggacgtttt gttattggag gtccgcaagg agactctgga
    43681 ttgaccggac gtaagattat tgtggatacc tatggaggct attcacgtca tggtggcggt
    43741 gctttttcag gaaaagatgc gacaaaagtg gaccgttcgg cttcttacgc tgctcgttat
    43801 attgctaaaa accttgtggc agcaggtctt gcgacgaaag ctgaagtcca actagcttat
    43861 gcgattggag ttgctcagcc tgtgtctgtt cgcgtggata catttggaac ttcaacggtt
    43921 cctgaagctg ttttagaagc tgctgttcgt caagtctttg atttacggcc agcaggcatt
    43981 attcaaatgc ttgatttaaa acgcccgatt tacaaacaaa cagctgccta tggtcacatg
    44041 gggagaacag atattgattt gccatgggag cgtttaaata aggttgatgc tttagtagaa
    44101 gctgtaaaaa cagtattata aacgacaact ttattaaaaa agtagagtga gtgaaaaaat
    44161 cttactctgc ttttttgtta ttaaataagc ctttaaaagg gatgattaaa aattaagacg
    44221 tcaataattg tcaggcttca tgatttatga taaaatgaaa aggttgaatt ctagtataag
    44281 aaagttttga atgtatgcgt aaaattatta ttaatggcgg aaaagcctta tctggagaag
    44341 tggcagtttc aggggcaaaa aacagtgttg ttgcgcttat tccagcaatc atcttagccg
    44401 atgatattgt gattcttgat ggtgtacctg ctattagtga tgtagatagt ctgattgaaa
    44461 tcatggagct tatgggagca acagtaaact atcatggtga tactttagaa attgacccta
    44521 gaggggtgca agacatcccg atgccttacg gaaagattaa tagtcttcga gcttcctatt
    44581 atttctacgg tagtctttta ggccgttttg gacaagcagt tgttggctta cctggtggtt
    44641 gcgatttagg accaagacca attgacttgc atttgaaggc cttcgaggct atgggagttg
    44701 aagtgtctta tgagggtgaa aatatgaatt tatcgacaaa cggtcaaaaa attcatggcg
    44761 ctcatatcta tatggacacc attagtgtcg gtgctacaat taatactatg gttgcggcaa
    44821 caaaagctca aggtaaaacg gttattgaaa acgctgcacg tgagccagag attattgatg
    44881 tggctactct tttgaataac atgggtgcgc atattcgtgg agcaggtaca gatattatta
    44941 cgatacaagg tgttcagaaa ttgcatggta ctagacacca agttattcct gatcgtattg
    45001 aagcagggac ttatatcgct ttggcggcag ctattggaaa aggtgttaag atcactaatg
    45061 ttctttatga gcatttagag agtttcattg ctaagttaga agaaatgggt gtccgtatga
    45121 cggtagaaga ggatgctatc tttgttgaaa agcaaaaatc cctcaaggct attacaatta
    45181 aaacctctcc ttaccctggc tttgccactg atttgcaaca gccatta
//
LOCUS       DAXMQE010000014        41327 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.014, whole genome shotgun sequence.
ACCESSION   DAXMQE010000014 DAXMQE010000000
VERSION     DAXMQE010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 41327)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41327)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41327
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.014"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            <1..593
                     /locus_tag="ACF4ZO_000863"
     CDS             <1..593
                     /locus_tag="ACF4ZO_000863"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004371 - glycerone kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HFD5486423.1"
                     /translation="DISVEPKKQFQMRHRGLAGTILLHKILGAAAQSGASLDDLEHLA
                     FDLATEIATIGFATKSASLPNAALPLFDLPDHQISYGIGIHGEEGYRTVPFMSSEHLA
                     VEIVNKLQIKFHWQEDEHFILLVNNLGTATDLEQGIFLNDIHQLLDLEGLHLPFIKNG
                     KFMTSLDMTGISVTLCRLKDRQWLDYLQAPTNAYAW"
     gene            complement(697..1482)
                     /locus_tag="ACF4ZO_000864"
     CDS             complement(697..1482)
                     /locus_tag="ACF4ZO_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD5486424.1"
                     /translation="MAKLRRMHAIFIKQYLKQIMEYKVDFVVGVLGVFLTQGLNLLFL
                     SVLFQHIPSLEGWTFEQIAFIYGFSLIPKGIDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PISPLFHVLVETFQVDALGELLVGVILLVTTAGSIVWTLPKVLLFILVIPFATLIYTS
                     LKIATASISFWTKQSGAVIYIFYMFNDFSKYPMSIYHSFLRWLISFIIPFAFTAYYPA
                     SYFLTGQHLLFNIGGLVVVSLLVLALSLKLWKWGLGAYESAGS"
     gene            complement(1484..2302)
                     /locus_tag="ACF4ZO_000865"
     CDS             complement(1484..2302)
                     /locus_tag="ACF4ZO_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD5486425.1"
                     /translation="MWSFWKRYRPFLSAGIQELITYRVNFFLYRIGDVMGAFVAYYLW
                     KAVFDSSKQSLINGFTLSDMTFYIIMSFVTTLLTKSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFMEIGFRWIVLMSVGFPFLMVLSGIKVMAGLSILQVLASSCLYLVSLLLA
                     FLINFYFNICFGFSAFVFKNLWGSNLLKNALVAFMSGSLIPLAFFPKMVSIVLSFLPF
                     SSLVYTPVMIVIGKYSLSQIMEALSLQIFWLLVMVVLSQVIWKKVQYHLTIQGG"
     gene            complement(2304..3296)
                     /locus_tag="ACF4ZO_000866"
     CDS             complement(2304..3296)
                     /locus_tag="ACF4ZO_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFD5486426.1"
                     /translation="MVMIEVSHLQKNFSKTIKEPGLKGALKSFVHPQREIFEAVKDLS
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGYCRINGKIPQDNRQNYVRDIGAV
                     FGQRTQLWWDLALQETYVVLKEIYDVPEKAFRKRMDFLNEVLDLNEFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLS
                     DIEQLCDRIIMIDKGQEIFDGTVTQLKQSFGKMKSLSFELKPGQEQVVSQFMGLPDIT
                     VERHELSLDIQYDSSRYQTAEIIQKTMADFAVRDLKMTDVDIEDIVRRFYRKEL"
     gene            complement(3437..5380)
                     /gene="thrS"
                     /locus_tag="ACF4ZO_000867"
     CDS             complement(3437..5380)
                     /gene="thrS"
                     /locus_tag="ACF4ZO_000867"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004829 - threonine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006435 - threonyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HFD5486427.1"
                     /translation="MIKITFPDGAVREFESGVTTFDIAESLSKSLAKKALAGKFNDQL
                     IDTTRAIEEDGSIEIVTPDHKDAYEVLRHSAAHLFAQAAKRLFPNLHLGVGPAIAEGF
                     YYDTDNAEGQISNEDLPRIEAEMQKIVTENYPCIREEVTKEEALELFKDDPYKVELIN
                     EHAGAGLTVYRQGEFVDLCRGPHVPSTGRIQVFHLLNVAGAYWRGNSDNNMMQRIYGT
                     AWFDKKDLKAYLTRLEEAKERDHRKLGKELDLFMISQEVGQGLPFWLPDGATIRRTLE
                     RYITDKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPVMDMGDGEEFVLRPMNC
                     PHHIQVYKNHVRSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHIFVTPEQ
                     IQEEFQRALQLIIDVYADFNLTDYRFRLSYRDPNDTHKYYDNDEMWENAQSMLKAALD
                     EMGVDYFEAEGEAAFYGPKLDIQVKTALGNEETLSTIQLDFLLPERFDLKYIGADGEE
                     HRPVMIHRGVISTMERFTAILIETYKGAFPTWLAPHQVTVIPISNEAHIDYAWEVAKT
                     LRDRGVRADVDDRNEKMQYKIRTSQTSKIPYQLIVGDKEMEDKSVNVRRYGSKATHTE
                     SVEEFVENILADIARKSRPDAQA"
     gene            complement(5802..7136)
                     /locus_tag="ACF4ZO_000868"
     CDS             complement(5802..7136)
                     /locus_tag="ACF4ZO_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HFD5486428.1"
                     /translation="MRVGLFTDTYFPQVSGVATSIRTLKEELEKEGHEVYIFTTTDRD
                     VKRFEDPTIIRLPSVPFVSFTDRRVVYRGLISSYKIAKHYNLDIIHTQTEFSLGLLGK
                     MIGKALRIPVVHTYHTQYEDYVSYIANGKIIRPSMVKPLLRGYLKDLDGVICPSRIVL
                     NLLEGYKVTIPKRVIPTGIPLEKYIRDDITAEEVTNLKAELGIAGDETMLLSLSRISY
                     EKNIQAIINQMPAILAENAKIKLIIVGDGPYLQDLKHLAMQLEVDKHVTFTGMVPHDK
                     VALYYKACDFFISASTSETQGLTYIESLASGTPIIAHGNPYLDDVVTDKMFGTLYYAE
                     TDLTDAIIDAILKTPVMDKRLLAKKRYEISAQHFGKSIYTFYLDTLIARNSKEAQKLS
                     LYLNHSGKSSSLKLVQGAIHLPKRAAKVTAITSVKVVKAPIKLVHAIKDFLD"
     gene            complement(7138..8136)
                     /locus_tag="ACF4ZO_000869"
     CDS             complement(7138..8136)
                     /locus_tag="ACF4ZO_000869"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HFD5486429.1"
                     /translation="MKVLLYLEAENYLRKSGIGRAIKHQAKALSLVGQHFTTNPRETY
                     DLVHLNTYGLKSWLLMIKAQKAGKKVIMHGHSTEEDFRNSFIFSNLLSPWFKKYLCHF
                     YNKADAIITPTLYSKSLIESYGVKSPIFAVSNGIDLEQYGADPKKEAAFRRYFDIKEG
                     EKVVMGAGLFFLRKGIDDFVKVAQAMPDVRFIWFGETNKWVIPAQVRQMVNGNHPKNL
                     IFPGYIKGDVYEGAMTGADAFFFPSREETEGIVVLEALASRQHLVLRDIPVYYGWVDQ
                     SSAELATDIPGFIEALKKVFSGASNKVEAGYKVAQSRRLETVGHALVDVYKKVMEL"
     gene            complement(8267..9268)
                     /gene="ccpA"
                     /locus_tag="ACF4ZO_000870"
     CDS             complement(8267..9268)
                     /gene="ccpA"
                     /locus_tag="ACF4ZO_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002264971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0001228 - DNA-binding transcription
                     activator activity, RNA polymerase II-specific [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HFD5486430.1"
                     /translation="MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFSILAKGIDDIAAMYKYNIVLASS
                     DEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
                     VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGL
                     VFEANYSYKEGFELAQRVINSGATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSN
                     DSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEILLNHGIKKRGTTK"
     gene            9442..10527
                     /locus_tag="ACF4ZO_000871"
     CDS             9442..10527
                     /locus_tag="ACF4ZO_000871"
                     /EC_number="3.4.11.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HFD5486431.1"
                     /translation="MTKLDQIRLYLDQKGAELAIFSDPVTINYLTGFFCDPHERQLFL
                     FVYHDLAPVLFVPALEVARASQAISFPVFGYVDSENPWEKIKAVLPNTAAKTIYAEFD
                     HLNVNKFHGLQTIFSGQFNNLTPYVQGMRLVKSADEINKMMIAGQFADKAVQVGFDNI
                     SLDATETDVIAQIEFEMKKQGIHKMSFDTMVLTGNNAANPHGIPGTNNIENNALLLFD
                     LGVETLGYTSDMTRTVAVGQPDQFKIDIYNLCLEAQLAAIDFIKPGVTAAQVDAAARQ
                     VIEKAGYGEYFNHRLGHGIGMDVHEFPSIMAGNDLVLEEGMCFSVEPGIYIPGKVGVR
                     IEDCGHVTKNGFEVFTHTPKELLYFEG"
     gene            10576..11241
                     /locus_tag="ACF4ZO_000872"
     CDS             10576..11241
                     /locus_tag="ACF4ZO_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HFD5486432.1"
                     /translation="MDQTIHHQIQQALHFRTAVRVYKEEKISDEDLALILDAAWLSPS
                     SVGLEGWRFVVLDNKPIKEEIKPFAWGAQYQLETASYFILLIAEKHARYDSPAIKNSL
                     LRRGIKEGDGLNSRLKLYESFQKEDMDMADNPRALFDWTAKQTYIALGNMMMTAALLG
                     IDTCPIEGFHYDKVNHILAKHNVIDLEKEGIASMLSLGYRLRDPKHAQVRKPKEEVIS
                     VVK"
     gene            11252..11629
                     /locus_tag="ACF4ZO_000873"
     CDS             11252..11629
                     /locus_tag="ACF4ZO_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFD5486433.1"
                     /translation="MKALHTCIRVKDLDQSVAFYTSAFPFKENYRKDFPDSQFTLVYL
                     ALEGESYELELTYNYGHGDYDLGNGYGHIALGSEHFEADHKKHRQAGFPVTDIKELAD
                     KSARYYFIQDPDGYKIEVIDLNN"
     gene            11774..12700
                     /locus_tag="ACF4ZO_000874"
     CDS             11774..12700
                     /locus_tag="ACF4ZO_000874"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFD5486434.1"
                     /translation="MTLLSIIVPCFNEEANILPYFEEMHQLETSMSNQLAFEYIFIDD
                     GSKDNTLGILRELAARFPNVHYLSFSRHFGKEAGLLAGLKEAKGNYITVMDVDLQDPP
                     ELLPVMYAKLKEGYDIVGTRRQNRQGEPLIRSMCSNLFYGLIKHLSDTEMVNGVRDYR
                     LMTRQVVDSILELGEVNRFSKGIFSWVGYRITYLSFENQKRKYGKSRWHFWELLRYSL
                     DGFINFSEMPLTIATWTGTFSFLISIFAILFIIIRKILFGDPVSGWASTVSIILFMGG
                     IQLFCMGIIGKYISKIFLETKKRPLYIIKEKH"
     gene            12911..13594
                     /locus_tag="ACF4ZO_000875"
     CDS             12911..13594
                     /locus_tag="ACF4ZO_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HFD5486435.1"
                     /translation="MEWIKLIGIVIIVLGFILKFDAIATVVVAGLVTALVSGISFVDF
                     LDILGKEFTNQRLLTIFFITLPLIGLSETYGLKHRATQLIQRVQSLTVGRLLTLYLII
                     RELAGLFSIRLGGHPQFVRPLIQPMGEAAAKANIGEELTDTEKDDIKAMAAANENFGN
                     FFAQNTFVGAGGVLLIAGTLEQLGYDGNQAKIAFSSILIAIISIIIVAIYNYLFEKKM
                     ERQHQKGDN"
     gene            13594..14520
                     /locus_tag="ACF4ZO_000876"
     CDS             13594..14520
                     /locus_tag="ACF4ZO_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 family protein"
                     /protein_id="HFD5486436.1"
                     /translation="MANIANLVLETIYILIGLQLFHTAYCTFKDKTNPVYFGTALFWG
                     LLGVTFVGGAFLPNKVIGFIVIVLALLTLFKQVRIGTLPAFNEQKAEESAHRIGNWIF
                     LPVMLMAMISLLLALILPDFSKSAIGIAGILATIAILIITKQKPSALLAENNRMNQQV
                     STSGILPQLLGALGAIFAAAGVGDVIASLIREIVPADSRFFGVLAYVLGMVIFTMIMG
                     NAFAAFTVITTGIGVPFVFALGADPIIAGALAMTAGFCGTLLTPMAANFNALPVALME
                     IKDRNAVIKKQAPIALVLIITHIALMYLLAYY"
     gene            14570..15217
                     /gene="pcp"
                     /locus_tag="ACF4ZO_000877"
     CDS             14570..15217
                     /gene="pcp"
                     /locus_tag="ACF4ZO_000877"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016920 - pyroglutamyl-peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HFD5486437.1"
                     /translation="MKILVTGFDPFGGEAINPALEAIKKLPATIHGAEIKCIEVPTVF
                     QKSADVLQQHIESFQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RADGKAAYFSTLPIKAMVAAIHQAGLPASVSNTAGTFVCNHLMYQALYLVDKYCPNAK
                     AGFMHIPFMMEQVVDKPNTAAMNLDDITRGIEAAIFAIVDFKDRSDLKRVGGATH"
     gene            complement(15334..16053)
                     /locus_tag="ACF4ZO_000878"
     CDS             complement(15334..16053)
                     /locus_tag="ACF4ZO_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminyl-peptide cyclotransferase"
                     /protein_id="HFD5486438.1"
                     /translation="MSIMITKGQVRLLRTYSYDSNLYTQGLEQLNNNHILLSAGRYGF
                     SKVGVYDLTQEIFSEKIAFPDTVFAEGLTVVEDYFWLLTYKEGVAYKFDKATCNCLGA
                     YPFEGDGWGLAYDKENQCLWMTSGNAFLQKRDPKDFALLDTVLVAIESVPISMLNELE
                     YVDGYLYANIWQTNTIVKLQPDSGKVVATYDISPLLKALNLDKSHYPDLNVLNGIAHL
                     DQQRFLITGKLYPLMLEVVLD"
     gene            complement(16059..16526)
                     /gene="smpB"
                     /locus_tag="ACF4ZO_000879"
     CDS             complement(16059..16526)
                     /gene="smpB"
                     /locus_tag="ACF4ZO_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HFD5486439.1"
                     /translation="MAKGEGHILAQNKKARHDYHIVETVEAGIVLTGTEIKSVRAARI
                     QLKDGFAQIKNGEAWLVNVHIAPFEQGNIWNADPERTRKLLLKKREITHLANELKGSG
                     MTLVPLKVYLKDGFAKVLIGLAKGKHEYDKRETIKRRDQERDIKKQMKHYNAR"
     gene            complement(16529..18862)
                     /gene="rnr"
                     /locus_tag="ACF4ZO_000880"
     CDS             complement(16529..18862)
                     /gene="rnr"
                     /locus_tag="ACF4ZO_000880"
                     /EC_number="3.1.13.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HFD5486440.1"
                     /translation="MMKERIMTYLKEHGKSNVNDLAAALEMAGAKQFPSLIKTISKME
                     SQSLLRFSDDGSLALRKEREKKKEPTVQGVFRANKAGFGFLHVDENEDDMFIGRNDVG
                     YAIDGDTVEVVVKKPADRLKGTAAEAKIVAIVDRSLKTAVGTFILDDDKPKYAGYIRS
                     KNQKIQQKIYIKKEPVVLKGTEIIKVDIDKYPTRGHDYFVASVRDIVGHQGDVGIDVL
                     EVLESMDIVSEFPAEVLAEANAISEAPTAKDLIGRVDLRQETTITIDGADAKDLDDAI
                     HIKLLDNGNYELGVHIADVSYYVTEGSSLDKEAIARGTSVYVTDRVVPMLPERLSNGI
                     CSLNPNVDRLTQSALMEINPQGYVVNYQICQSVIKTTYRMTYSTVNDMIAGDEEALQE
                     FASIADDVTLMVTLHRILEAMRSKRGALNFDTQEAKVIVNDKGMPVDVVLRQRGIAER
                     MIESFMLAANECVAEHFAKAKLPFIYRIHEEPKVEKLQQFIDYASTFGIHIQGTANKI
                     SQEALQAFMAKVEGQPGAEVLNMMLLRSMQQARYSEHNHGHYGLAAEYYTHFTSPIRR
                     YPDLLVHRMVREYNQPSQEKRDHFAQIIPELATSSSQLERRAIDAERVVEAMKKAEYM
                     AEYVGEEFDGIVSSVVKFGFFVELPNTIEGLVHITSLPEYYHFNERTLSLQGEKSGKV
                     FKVGQPIRVKLVKADKETGDIDFEYLPSDFDVVEKIKMSDKASRRDRRKSSKSSKGTK
                     KKEPKEVAKAKTKGKTKKGSKKPFYKEQAKKKSRKRS"
     gene            complement(18956..19192)
                     /gene="secG"
                     /locus_tag="ACF4ZO_000881"
     CDS             complement(18956..19192)
                     /gene="secG"
                     /locus_tag="ACF4ZO_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015136 - sialic acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015739 - sialic acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HFD5486441.1"
                     /translation="MYNLLLTILLVLSVLLVIAIFMQPQKNPSSNVFDSSGSEALFER
                     TKARGFEAFMQRFTAVLVFFWLAIALVLAILSSK"
     gene            complement(19238..19384)
                     /gene="rpmG"
                     /locus_tag="ACF4ZO_000882"
     CDS             complement(19238..19384)
                     /gene="rpmG"
                     /locus_tag="ACF4ZO_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HFD5486442.1"
                     /translation="MRVKINLECSECGSNNYLTSKNKSSHPEKIKVPKYCPKERKVTL
                     HVET"
     gene            complement(19381..20574)
                     /locus_tag="ACF4ZO_000883"
     CDS             complement(19381..20574)
                     /locus_tag="ACF4ZO_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HFD5486443.1"
                     /translation="MNWRQNLKVAWLGNFFTGASFSLVMPFMALYVENLGTPTELVEY
                     CAGLAVAVTALASALFAPVWGKLADRYGRKPMMLRASFVMTFTMGGLAIIPNVFWLLI
                     LRLLTGVFAGYVPNATALIASQAPKEESGYALGTLATGVTAGALIGPLLGGILAELLG
                     IRQVFLLVGVILFLCSLMTAVYVKEEFKPIRRFEMIPTKVILKQVKSPQIMLGLFVTS
                     MIIQISAQSVAPILSLYIRHLGQTHNLMFTSGLVVSAMGFSSLFSSSYLGKLGDRFGN
                     HRLLLAALCYSFIMYFSSALAQTSFQLGVLRFAYGFGVGALMPSINSLLTKLTPKEGI
                     SRVFAYNQMFSNLGQVIGPFIGSNVAVVLGYRSVFYVTSLIVFVNLIWSLIIFRKYIK
                     VKDIV"
     gene            complement(20696..22198)
                     /locus_tag="ACF4ZO_000884"
                     /pseudo
     CDS             complement(20696..22198)
                     /locus_tag="ACF4ZO_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560520.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helicase HerA-like domain-containing protein"
     gene            complement(22388..22981)
                     /gene="coaE"
                     /locus_tag="ACF4ZO_000885"
     CDS             complement(22388..22981)
                     /gene="coaE"
                     /locus_tag="ACF4ZO_000885"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017469.1"
                     /note="Dephospho-CoA kinase (CoaE) performs the final step
                     in coenzyme A biosynthesis; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004140 - dephospho-CoA kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HFD5486444.1"
                     /translation="MIIGITGGIASGKSTVVKVIRKAGYQVIDADQVVHDLQEKGGRL
                     YEALREAFGNQILKADGELDRTKLSEMLFSNPDNMATSSAIQNQIIKEELAAKRDHLA
                     QSQAIFFMDIPLLMELGYQDWFDAIWLVYVDAQTQLQRLMARNRLDKGKARQRIASQL
                     PIEEKKPYASLVIDNNGDMETLIKQVQSALLSLANPR"
     gene            complement(22978..23805)
                     /gene="mutM"
                     /locus_tag="ACF4ZO_000886"
     CDS             complement(22978..23805)
                     /gene="mutM"
                     /locus_tag="ACF4ZO_000886"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008534 - oxidized purine nucleobase
                     lesion DNA N-glycosylase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HFD5486445.1"
                     /translation="MPELPEVETVRRGLKALVLGQEIVAVTLKVPKMVKTDLETFALT
                     LPGQIIQSVGRRGKYLLIDLGQLVLVSHLRMEGKYLLFPDEVPDNKHFHVFFELKNGS
                     TLVYQDVRKFGTFDLIAKSQLSAFFAKRKLGPEPKKETFKLKTFEAVLLSSKKTIKPH
                     LLDQTLVAGLGNIYVDEVLWAAKVHPETASSRLNKAEIKRLHDETIRILALGIEKGGS
                     TVRTYRNTLGADGTMQDYLQVYGQTGKPCPRCGQAIVKLKVGGRGTHICPKCQKKRP"
     gene            complement(23977..24843)
                     /gene="rgg2"
                     /locus_tag="ACF4ZO_000887"
     CDS             complement(23977..24843)
                     /gene="rgg2"
                     /locus_tag="ACF4ZO_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg2"
                     /protein_id="HFD5486446.1"
                     /translation="MEKELGKTLRRLRKGKQVSISFLADEYLSKSQISRFERGESEIT
                     CSRLLNLLDKLNITIDEFVSAHSKTHTHFFTLLSQARKCYAEKNVVKLTKLLKDYAHK
                     DYERTMIKAILFSIDSSIAPSQEELTRLTDYLFKVEQWGYYEIILLGNCSRFMNYNTL
                     FLLTKEMVASFAYSEQNKTNKMLVTQLSINCLIISIDHSCFEHSRYLINKIDLLLRDE
                     LNFYEKTVFLYVHGYYKLKQKEISGEEDMRQALQIFKYLGEDSLYYSYKEHYRQIVLG
                     GKGDEDWSEADL"
     gene            24932..25000
                     /gene="shp2"
                     /locus_tag="ACF4ZO_000888"
     CDS             24932..25000
                     /gene="shp2"
                     /locus_tag="ACF4ZO_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_128650799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide pheromone SHP2"
                     /protein_id="HFD5486447.1"
                     /translation="MKKVNKALLFTLIMDILIIVGG"
     gene            25150..25392
                     /locus_tag="ACF4ZO_000889"
     CDS             25150..25392
                     /locus_tag="ACF4ZO_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486448.1"
                     /translation="MKQQGHTVMMCLNKTLTIKLSAPLTSNDLVPLSTNEVIIMEPLL
                     HLLPKVVPVLIHLVDKANVSWLTVILQLPILLKTIW"
     gene            25341..25520
                     /locus_tag="ACF4ZO_000890"
     CDS             25341..25520
                     /locus_tag="ACF4ZO_000890"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486449.1"
                     /translation="MVNSDITVTYTLKDNLVALHKEYKTFVKKNITDKPITSDYDKAK
                     VIYNHLINEYTYATK"
     gene            25915..26184
                     /gene="stcA"
                     /locus_tag="ACF4ZO_000891"
     CDS             25915..26184
                     /gene="stcA"
                     /locus_tag="ACF4ZO_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system protein StcA"
                     /protein_id="HFD5486450.1"
                     /translation="MTKKQFYLILAISILCFILAVSPKPPIPKHTIEKKRTAMTIGHS
                     KQNPHKKEALKHKKNKNKTLFLPSGDSAIKSVISMTVRLLLDDQS"
     gene            complement(26532..26930)
                     /locus_tag="ACF4ZO_000892"
                     /pseudo
     CDS             complement(26532..26930)
                     /locus_tag="ACF4ZO_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635342.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
     gene            complement(27023..28093)
                     /locus_tag="ACF4ZO_000893"
     CDS             complement(27023..28093)
                     /locus_tag="ACF4ZO_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486451.1"
                     /translation="MMMLRDVKVKTSSLLVGCAATLLVSLSSTVAADSVHSSDRRFGV
                     GYKEETTSQFSSDQPSQVVLYRGEANTVRFTYTNQMYLMKDIRIALDGSGKSLTAQTV
                     PGMGHVYEGFQTSARGIFTMSGVPESTVPVANPNVQTKYTRYFKVIDDMHNTMYKGTV
                     FLVQPQAWKYTMKSVDQLPVDDLNHIGVAGIERMTTLIKNAGALLTTGGSGAFPDNIK
                     VSINPKGRQATITYGDGSTDIIPPAVLWKKGSVKEPTEADQSVGTPTPGIPGKFKRDQ
                     SLNEHEAMVNVEPLSHVVKDNIKVIDEKSTGRFEPFRPNEDEKEKPASDVKVRPAEVG
                     SWLEPATALPSVEMSAEDRLKS"
     gene            complement(28344..28745)
                     /locus_tag="ACF4ZO_000894"
     CDS             complement(28344..28745)
                     /locus_tag="ACF4ZO_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486452.1"
                     /translation="MRNILRFLGIVIISAVILFSIGSFYDLPLMKNIQLICWSFILDL
                     FVFVYKQRQTTEVLTWYQVVKQFWLFIKCTILIPTLIAFIIIIGCLTSISEVSIYFYL
                     HLTVVCYTIGMILSLGRLISPNHSIFNKLKK"
     gene            complement(28924..29220)
                     /locus_tag="ACF4ZO_000895"
     CDS             complement(28924..29220)
                     /locus_tag="ACF4ZO_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486453.1"
                     /translation="MKTLDIIFNLSDRKMIFLENVEKLGGYIVPFTLIILSVAYNFRH
                     PYPIWAAVLGGISLIVIFIYFILIVYLYLRYRYLVWKKIPEIKINSTELSCNHI"
     gene            complement(29270..29464)
                     /locus_tag="ACF4ZO_000896"
     CDS             complement(29270..29464)
                     /locus_tag="ACF4ZO_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HFD5486454.1"
                     /translation="MEVLKNGLAIINGGGKDGANIFLTGMAGAAQGVTVCAQTGVFIP
                     WQGYILCGAAGAATNIIWPH"
     gene            complement(29759..29959)
                     /locus_tag="ACF4ZO_000897"
     CDS             complement(29759..29959)
                     /locus_tag="ACF4ZO_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class IIb bacteriocin, lactobin A/cerein 7B
                     family"
                     /protein_id="HFD5486455.1"
                     /translation="MTTMKELTINDMASISGGNAPGDAVIGGLGGLASGLKFCKLLHP
                     VLAGGCVVGFTVGGAYLGYTAN"
     gene            complement(29972..30199)
                     /locus_tag="ACF4ZO_000898"
     CDS             complement(29972..30199)
                     /locus_tag="ACF4ZO_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0042742 - defense response to bacterium
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HFD5486456.1"
                     /translation="MEIKKLETFHQMTIEKLAKVEGGKNNWQANVSGVIAAGSAGAAI
                     GFPVCGVACGYIGAKTAITLWAGVTGATGGF"
     gene            30517..31202
                     /locus_tag="ACF4ZO_000899"
                     /pseudo
     CDS             30517..31202
                     /locus_tag="ACF4ZO_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191693.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(31393..31575)
                     /locus_tag="ACF4ZO_000900"
     CDS             complement(31393..31575)
                     /locus_tag="ACF4ZO_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class IIb bacteriocin, lactobin A/cerein 7B
                     family"
                     /protein_id="HFD5486457.1"
                     /translation="MDNFLELQFEELVNISGGKGNIGSAIGGCLGGMLIAAAGGPITG
                     GAAAFVCVASGIAAYQ"
     gene            complement(31590..31835)
                     /locus_tag="ACF4ZO_000901"
     CDS             complement(31590..31835)
                     /locus_tag="ACF4ZO_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0042742 - defense response to bacterium
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HFD5486458.1"
                     /translation="MIKFAEEIQKEELFHIIGGYSATDCKNHLIGGITSGAIAGGVGA
                     GMATLGVGGVAGAFAGAHVGAIAGGLTCVGGMLFNGK"
     gene            32233..32487
                     /locus_tag="ACF4ZO_000902"
     CDS             32233..32487
                     /locus_tag="ACF4ZO_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486459.1"
                     /translation="MSGLFYHKSYFFKSEQVYDLLNEIRMRYPHAHIILIGNHINYEE
                     IFKNHYRVFGVIDTTSHKSLKSIRDQIQLYLDELYNSNNG"
     gene            complement(32793..33269)
                     /locus_tag="ACF4ZO_000903"
     CDS             complement(32793..33269)
                     /locus_tag="ACF4ZO_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HFD5486460.1"
                     /translation="MPHDYISYIRSKVGHDKIILNFAGGILTNDDSKVLMQLRGDKKT
                     WAIPGGTMELGESSLETCKREFLEETRIEVEAVRLLNVYTHFEEVYPNGDAVQTIVFI
                     YELTAVSDMAIDNFHNEETLKLQFFSHEEIAELESVSAKHRLMLEEYFSDSFAMGH"
     gene            complement(33289..34185)
                     /gene="era"
                     /locus_tag="ACF4ZO_000904"
     CDS             complement(33289..34185)
                     /gene="era"
                     /locus_tag="ACF4ZO_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HFD5486461.1"
                     /translation="MFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKIM
                     GIYTTETEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVETVLFMVPADEKRGKGDD
                     MIIERLKAAKIPVILVINKIDKVHPDQLLEQIDDFRSQMDFKEVVPISALEGNNVPTL
                     IKLLTDNLEEGFQYFPEDQITDHPERFLVSEMVREKVLHLTQQEVPHSVAVVVESMKR
                     DEETDKVHIRATIMVERDSQKGIIIGKQGAMLKKIGKMARRDIELMLGDKVYLETWVK
                     VKKNWRDKKLDLADFGYNEKEY"
     gene            complement(34305..34712)
                     /locus_tag="ACF4ZO_000905"
     CDS             complement(34305..34712)
                     /locus_tag="ACF4ZO_000905"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HFD5486462.1"
                     /translation="MALHDNNTTKRKWKNRTITSSLEFALTGVFTAFKEERNLRSHLL
                     SACLACVAGLFFSISAIEWLFLLLAIFLVITLEIVNSAIENVVDLASDYHFSMLAKNA
                     KDMAAGAVLMISGYAVLTGLIIFIPKIWNIFVH"
     gene            complement(34693..35190)
                     /gene="ybeY"
                     /locus_tag="ACF4ZO_000906"
     CDS             complement(34693..35190)
                     /gene="ybeY"
                     /locus_tag="ACF4ZO_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HFD5486463.1"
                     /translation="MYIEMIDETGQVSQEIMEQTLDLLNFAAQKTGKEEKEMSVTFVT
                     NERSHELNLEYRDTDRPTDVISLEYKPETPILFSQEDLAADPSLAEMMAEFDAYIGEL
                     FISIDKAREQSQEYGHSFEREMGFLAVHGFLHINGYDHYTLEEEKEMFTLQEEILTAY
                     GLTRQ"
     gene            complement(35349..35924)
                     /locus_tag="ACF4ZO_000907"
     CDS             complement(35349..35924)
                     /locus_tag="ACF4ZO_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HFD5486464.1"
                     /translation="MDDLTKAIMADEANLSYTERGIFPLYDAPQTARIIIVGQAPGIV
                     AQETKLYWNDRSGIRLRDWLGVDNDTFYHSGLFGIIPMDFYYPGKGKSGDLPPREGFA
                     AKWHPPLRALMPEVELTILVGRYAQDFYLGNKAYKTLTETVRHFEDYLPDYFPLVHPS
                     PRNQLWLAKNPWFEQDLLPILQKRVEAILTK"
     gene            complement(35970..37022)
                     /locus_tag="ACF4ZO_000908"
     CDS             complement(35970..37022)
                     /locus_tag="ACF4ZO_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HFD5486465.1"
                     /translation="MQEYSIDITLTHPDDVLALFGSNERHLKLIEAHLGVIVHARTER
                     VQVIGDDEEAVELARLTIKGLLVLVGRGMVVNTSDVVTALSMAESHQIDQFMALYEEE
                     IIKDNYGKAIRVKTLGQKTYVDSVKRHDVVFGVGPAGTGKTFLAVTLAVTALKRGQVK
                     RIILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYHILGKEQTTRLMERDVIEIA
                     PLAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFNSKMIVNGDTSQIDLPRNVKS
                     GLIDATQKLQGIKQIDFVYLSAKDVVRHPVVADIIKAYETSSEETKDLLKPKASDVEA
                     DYQPGLTKYPVIGQEH"
     gene            complement(37181..38953)
                     /locus_tag="ACF4ZO_000909"
     CDS             complement(37181..38953)
                     /locus_tag="ACF4ZO_000909"
                     /EC_number="4.2.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050151 - oleate hydratase activity
                     [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA];
                     GO_process: GO:0006631 - fatty acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oleate hydratase"
                     /protein_id="HFD5486466.1"
                     /translation="MYYTSGNYEAFATPRKPEGVDQKSAYIVGTGLAGLAAAVFLIRD
                     GHMAGERIHLFEELPLAGGSLDGIEKPHLGFVTRGGREMENHFECMWDMYRSIPSLEI
                     PGASYLDEFYWLDKDDPNSSNCRLIHKRGNRVDDDGQYTLGKQSKELIHLIMKTEESL
                     GDQTIEEFFSEDFFKSNFWVYWATMFAFEKWHSVVEMRRYAMRFIHHIDGLPDFTSLK
                     FNKYNQYDSMVKPIIAYLESHDVDIQFDTKVTDIQVEQTAGKKVAKTIHMTVSGEAKA
                     IELTPDDLVFVTNGSITESSTYGSHHEVAKPTKALGGSWNLWENLAAQSDDFGYPKVF
                     YQDLPAESWFVSATATIKHPAIEPYIERLTHRDLHDGKVNTGGIITITDSNWMMSFAI
                     HRQPHFKEQKDNETTVWIYGLYSNIEGNYVHKKIEECTGQEITEEWLYHLGVPVDKIK
                     DLASQDYINTVPVYMPYITSYFMPRVKGDRPKVIPDGSVNLAFIGNFAESPSRDTVFT
                     TEYSIRTAMEAVYSFLNVERGIPEVFNSAYDIRELLKAFYYLNDKKAIKDMDLPIPAL
                     IEKIGHKKIKDTFIEELLKDANLI"
     gene            complement(39268..40443)
                     /locus_tag="ACF4ZO_000910"
     CDS             complement(39268..40443)
                     /locus_tag="ACF4ZO_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HFD5486467.1"
                     /translation="MIITKKSLFVTSVALSLAPLATAQAQEWTPRSVTEIKSELVLVD
                     NVFTYTVKYGDTLSTIAEAMGIDVHVLGDINHIANIDLIFPDTILTANYNQHGQATTL
                     TVQAPASSPASVSHVPSSEPLPQASATSQSTVPMAPSATPSDVPTTPLASAKPDSFVT
                     ASSELTSSTNDVSTELSSESQKQPEVPQEAVPTPKAAETTEVEPKTDISEDPTSANRP
                     VPNESASEEVSSAAPAQAPAPAEKEKTSAPAAQKAVADTTSVATSNGLSYAPNHAYNP
                     MNAGLQPQTAAFKEEVASAFGITSFSGYRPGDPGDHGKGLAIDFMVPENSALGDQVAQ
                     YAIDHMAERGISYVIWKQRFYAPFASIYGPAYTWNPMPDRGSITENHYDHVHVSFNA"
     gene            complement(40599..40814)
                     /locus_tag="ACF4ZO_000911"
     CDS             complement(40599..40814)
                     /locus_tag="ACF4ZO_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HFD5486468.1"
                     /translation="MRKSFYSWLMTQRNPKSNEPVAILADLVFDDTTFPKHTNDFELI
                     SRYLEDQASFSFNLGQFDEIWEDYLAH"
     gene            complement(40811..41320)
                     /gene="msrA"
                     /locus_tag="ACF4ZO_000912"
     CDS             complement(40811..41320)
                     /gene="msrA"
                     /locus_tag="ACF4ZO_000912"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008113 - peptide-methionine (S)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_function: GO:0033744 -
                     L-methionine:thioredoxin-disulfide S-oxidoreductase
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HFD5486469.1"
                     /translation="MERAIFAGGCFWCMVQPFEEQAGILSVRSGYTGGHLPNPSYEQV
                     CAKTTGHTEAVEIIFDPEEISYKELVELYWAQTDPTDAFGQFEDRGDNYRPVIYYTTE
                     RQKEIAEQSKANLQASGRFDQPIVTTIEPAEPFYLAEDYHQGFYKKNPKRYAQSSAIR
                     HQFLEENWS"
BASE COUNT        12546 a         8864 c         7318 g        12599 t
ORIGIN      
        1 acgatatctc ggttgaacct aaaaagcaat tccaaatgcg ccaccgagga ctcgctggaa
       61 ctatattgct tcacaaaatc ttaggagcag ctgcacaaag tggggcaagt ttggatgacc
      121 ttgaacacct agcttttgac cttgccacag agattgctac catcggattt gcaaccaaat
      181 ctgctagcct acccaatgcg gcactacctc tttttgactt gcctgatcat cagatttcat
      241 atgggattgg tattcatggt gaagaaggct atcgcacggt cccatttatg tcatcagagc
      301 atcttgctgt ggaaattgtt aataagcttc aaattaaatt ccattggcaa gaagacgaac
      361 attttattct tctagttaat aatttaggaa cagcaaccga cttggaacaa ggcatttttc
      421 tgaatgatat ccatcaactt ttagatcttg aagggcttca tcttcctttt atcaaaaacg
      481 gaaaattcat gactagcctt gacatgactg gtatctctgt taccctttgc cgtcttaaag
      541 atagacagtg gctagactac ttacaagctc caaccaatgc ctacgcttgg taaaccatca
      601 caaaaaaggc agccattttt acaacagctg ccttccttca ttatctaggt tttcatattc
      661 tgacctaaac gattttcaat ttgtttaaga gtctctctag gaaccagcac tttcataagc
      721 acctagtccc catttccaaa gcttaagcga caaggccaaa accagtaacg acaccactac
      781 caagcctcca atattaaaga gcaggtgctg acctgttaaa aaataagaag cagggtaata
      841 agctgtaaaa gcaaagggaa tgataaaact gattaaccac cgcaaaaagg aatggtaaat
      901 agacataggg tacttggaaa agtcattaaa catgtaaaaa atatagataa ctgccccaga
      961 ctgcttggtc caaaaagaaa tgctggcggt cgcaattttt aaagaggtgt aaatcaaggt
     1021 cgcaaaagga ataaccagaa taaacaaaag caccttagga agagtccata cgatactacc
     1081 agccgtggtc actaataaga taaccccaac caataattca cccagggcat ccacttgaaa
     1141 tgtctcaacc aaaacatgaa ataaaggact aattggtcta gtgaggtact tgtcaaattc
     1201 tcctttgcgg acaagccgtt gccctaaagc ccaaagattg tcaaaaaaga ggtgatcaat
     1261 tccctttgga atcaaagaaa agccataaat aaaggcaatt tgttcaaacg tccagccttc
     1321 taaagaaggg atatgttgga aaagtaccga taaaaagagc agattaagtc cctgagtgag
     1381 aaaaacacct agcactccca ccacaaaatc aaccttgtat tccataattt gtttgaggta
     1441 ttgtttgata aaaatagcgt gcatacgtct caattttgcc atctcaccct ccttgaatcg
     1501 ttaaatggta ctgaaccttt ttccagataa cttgcgataa gactaccatc accagtaacc
     1561 aaaagatttg caaacttagg gcctccatta tctgactaag gctgtatttc ccaatgacaa
     1621 tcataactgg cgtgtaaacc aaagaggaaa acggtagaaa actaagcact atagaaacca
     1681 ttttaggaaa aaaagccaat ggaatcaaac tgcctgacat aaaggcaacc aaggcatttt
     1741 tcaataaatt agacccccaa aggtttttaa agacaaatgc tgaaaagcca aaacaaatgt
     1801 tgaaataaaa attgattaaa aaagctaata aaaggctaac taaatacaga caactgctgg
     1861 ctaggacttg caagatagac agccccgcca tgactttaat accagataag accattaaaa
     1921 aaggaaagcc gacactcatt agcacaatcc agcgaaaacc aatttccata aagaggtaag
     1981 aggctgcaaa atgaactggt cgaagcaggc gcatgatgat agaaccatct ttcacttctt
     2041 cgccaatcat aaaggagctg tctgatttgg tcagtaaagt ggtcacaaaa ctcatgataa
     2101 tgtaaaaggt catgtcagac agagtaaaac cattgattaa ggattgctta gacgaatcaa
     2161 aaacagcctt ccagaggtaa taagccacaa aagcccccat gacatctcca atacgataca
     2221 aaaagaaatt aacgcgatag gttattaatt cctgaattcc tgcactgaga aagggtctat
     2281 aacgtttcca aaatgaccac atcttaaagc tcctttcggt agaaacgacg aacaatatcc
     2341 tcaatatcta catcagtcat cttcaaatcc ctgaccgcaa aatcagccat ggttttttga
     2401 ataatctccg ctgtttgata gcgcgaactg tcatattgaa tgtctaaact aagctcatgc
     2461 cgttccactg tgatgtcagg taagcccata aactgtgaga ccacctgctc ctgccctggc
     2521 ttcaactcaa aagacagact cttcattttt ccaaagcttt gctttaattg ggtcaccgtt
     2581 ccatcaaaga tttcttgccc tttatcaatc atgataatcc gatcacagag ctgttcaata
     2641 tcactcaaat catgggtcgt cagtaaaata gttgtctctt cttcttgatt aatttgagta
     2701 atggcacgcc gaatgttgtc cttcacagaa acatcaagtc caatcgttgg ttcatctaaa
     2761 aacaatactt taggattatg caacaaggaa gcagcaatat cagctcgcat ccgctgaccg
     2821 agtgataagg tccggacagg atccttaata aactcattca ggtccaaaac ctcatttaaa
     2881 aaatccatgc gcttgcgaaa ggctttttca ggcacatcgt aaatttcttt taacacgaca
     2941 taggtctctt gcaaggccaa atcccaccat agttgtgttc gttgaccaaa aacagctcca
     3001 atgtctctca cataattttg acgattatct tgtggaatct ttccgttaat gcgacagtaa
     3061 cctgatgtag gctttaaaat acctgttaac atcttaatcg ttgttgattt tcctgcacca
     3121 ttggctccaa taaaacctaa aatttgccct ttgggtacct caaaagataa gtccttaacc
     3181 gcctcaaaga tttctctttg gggatgaaca aaggacttca aggctccctt taatcctggc
     3241 tctttaatgg ttttggaaaa atttttttga aggtgggaca cttctatcat gaccatttac
     3301 cattcctcgt ttctgttatc gtcttatcac cgttactaaa caatttatta taacaccata
     3361 aaaaagactg tgcaaccgtt tgcttaattt tttaagaaag aaaaagaagc ccataaggac
     3421 ctctttttgc cattgattaa gcttgtgcat ctggacgtga cttgcgagca atgtctgcca
     3481 agatgttttc cacaaattct tccacagatt cagtgtgagt cgccttacta ccatagcggc
     3541 gaacattgac tgatttgtct tccatttctt tgtccccaac aattaattgg taaggaattt
     3601 tgctggtttg agacgtacga atcttgtact gcattttttc attgcggtca tcgacatctg
     3661 cacgaacacc acggtcacga agggtttttg ctacttccca agcatagtca atgtgggctt
     3721 catttgaaat tggaatcacg gttacttggt gaggtgccaa ccaagttggg aaagcaccct
     3781 tgtaagtttc aataaggata gcagtgaaac gttccatagt tgagataaca ccacggtgaa
     3841 tcatgactgg gcggtgttct tcgccatctg caccaatgta tttaaggtca aagcgttctg
     3901 gcaacaagaa gtccaactga atggttgata gggtttcttc gttaccaaga gctgttttca
     3961 cctgaatatc aagcttaggc ccataaaagg ctgcttcacc ttctgcttca aagtaatcta
     4021 cacccatctc atcaagtgca gctttaagca tactttgagc attttcccac atctcatcat
     4081 tgtcataata tttatgagta tcgttagggt ctcggtatga caaacgaaaa cgataatcag
     4141 tcaagttgaa gtcagcataa acatcaatga ttaattgaag ggcacgttga aattcttcct
     4201 ggatttgctc tggtgttacg aaaatgtggc catcattcaa ggtcatttca cgtacccgtt
     4261 gaagtcctga tagggcacct gatttttcgt aacggtgcat catgccaagc tcggcaatac
     4321 gaataggcaa ttcacgataa gaacgcacat gatttttata cacttgaatg tggtgtgggc
     4381 agttcattgg acgaagaaca aactcctcac catctcccat atccattaca gggaacatat
     4441 cttcttgata atgatcccaa tgacctgatg tcttgtacaa ttctacagaa gcaagtggtg
     4501 gtgtgtaaac gtgttggtag cctgatgcta attctttatc tgtgatgtag cgctcaagtg
     4561 tacgacgaat agtcgctcca tctggtaacc aaaatggcaa gccttgacca acttcttgac
     4621 taatcatgaa caagtcaagc tctttaccaa gcttacggtg atcacgttct ttggcttctt
     4681 ctagacgagt caagtaagct ttgaggtctt ttttatcaaa ccaagctgtt ccatagatac
     4741 gttgcatcat gttattgtcg ctgttaccac gccagtaagc acccgccaca ttgagcaagt
     4801 ggaagacttg gatacggcct gttgatggca catgagggcc acggcaaaga tccacaaatt
     4861 caccttgacg gtaaaccgtc aagccagcac cagcatgctc attaatcaat tctaccttgt
     4921 atggatcatc tttgaacaat tccaaagctt cttctttggt cacttcttca cggatacatg
     4981 ggtaattttc tgtcacgatt ttttgcattt cagcttcgat acgtggcaaa tcttcgtttg
     5041 aaatttggcc ttcagcatta tctgtatcat agtaaaagcc ttctgcaatg gcagggccca
     5101 cacccaaatg aagatttggg aacaagcgtt ttgcagcttg ggcaaataaa tgggctgcag
     5161 agtggcgaag cacctcataa gcatctttgt gatcaggtgt cacgatttca atactgccat
     5221 cttcttcaat ggcacgagtg gtgtcaatga gttgatcatt gaacttacca gctaaagctt
     5281 ttttagccaa tgatttgctg agggactcag caatgtcaaa cgttgttacg ccagattcaa
     5341 attcacgcac ggcgccatct ggaaaagtaa tcttaatcat ttgctttctc ctttaagtca
     5401 gttaagattt ccactaaaac atggatagta agacaaatta gggacaagag gttagtgaat
     5461 agctcaacac caccacgtag aagaacaata ccttattcac gaatctaccc tccctagtcc
     5521 ttaaaaacaa ggctaatccc ctccaaaaca aaaaaactga ccgcatccca aaggacgcaa
     5581 tcagcgtggt tccaccttaa tttatgcagg acaaaaaaca tgccttgcac ctctagtggc
     5641 gataaggggg ccaccctttt atgtttgcat aaaaaccagg aaggagtatc agattagcta
     5701 tccttgtgct ctttccacca accagcactc gcttaaaaga ttctgtccaa tctaacttgt
     5761 cttcaagatt attatagcaa gttttcaaaa atttacaagc cttaatccag aaaatctttg
     5821 atagcatgga ccagcttgat aggagccttg actactttta ctgaggtgat agctgtgacc
     5881 ttagcagcac gtttaggcaa gtgaatagca ccttgcacta attttagaga actactttta
     5941 ccagaatgat taagataaag actcagcttt tgagcttctt tgctatttct agcaattaac
     6001 gtatctaaat agaacgtgta aatagatttt ccaaagtgct gtgctgagat ttcataacgt
     6061 ttttttgcta ataaccgttt atccataact ggtgttttta gtatggcatc aataatagca
     6121 tcagttaaat ctgtttcagc gtaataaagt gtgccaaaca ttttatcagt caccacatca
     6181 tctaagtaag gattgccatg agcaataata ggagtgccac tagccaaact ttcaatatag
     6241 gtcaagccct gagtctcact agttgatgct gagataaaga aatcacaagc cttatagtac
     6301 agagcaacct tatcatgagg caccatgcct gtaaaggtca cgtgtttgtc aacctctaac
     6361 tgcatcgcca agtgtttcaa atcttgcaaa taggggccat ctcctacaat aataagcttt
     6421 atcttggcat tttcagccaa aatagctggc atctgattga tgatagcttg aatatttttt
     6481 tcataagaaa tccgtgacaa actcaataac atggtttcat caccagcaat gcccaattct
     6541 gcttttaagt tggttacttc ttctgctgtg atgtcatcac gaatatattt ttccaaagga
     6601 atgcctgttg ggataacccg cttagggata gtcactttgt aaccttctag aagattgagg
     6661 acaatcctgc ttgggcagat aaccccatcc aaatccttca aatagcccct aagaagaggt
     6721 ttgaccatac ttggtcgaat gatttttccg ttggcaatat aactcacgta gtcctcatat
     6781 tgggtatggt aagtatggac aacaggaatt cgcaaagctt tgcctatcat tttccctaat
     6841 aagcctaagc taaactcagt ttgcgtatga ataatatcaa gattatagtg ttttgcaatt
     6901 ttgtatgacg aaatgaggcc acgataaacc acacgtctat ccgtaaatga cacaaaagga
     6961 acacttggca gtcgaataat ggtcgggtct tcaaagcgtt tgacatctct atcagtagtg
     7021 gtgaaaatat aaacttcgtg accttctttt tctagctctt cttttaacgt acgaatacta
     7081 gtagcgactc ctgaaacttg tggaaaatag gtatctgtga atagacctac acgcatctta
     7141 taactccatt acttttttat agacatctac taaggcatgg ccaaccgttt ctaggcgacg
     7201 actctgggca accttgtaac cagcttcaac tttgttgctg gcaccagaaa agactttttt
     7261 cagagcttct ataaaacctg gtatatcggt tgctaattcc gcactacttt gatcaaccca
     7321 tccgtagtaa actggtatat cacgtaaaac aaggtgctgg cgactggcca aggcttctaa
     7381 gacaacaatg ccttctgttt cttcacgact tggaaagaaa aaggcatctg caccagtcat
     7441 ggcaccttca taaacatccc ctttaatgta tcctgggaaa ataagatttt tcgggtggtt
     7501 accattgacc atttggcgaa cttgagcagg aatgacccat ttgttggtct cgccaaacca
     7561 gataaaacga acatctggca tagcttgggc aactttgaca aagtcatcaa ttcctttcct
     7621 cagaaaaaat aatcctgctc ccataaccac tttttcaccc tctttaatgt caaagtagcg
     7681 acgaaaagct gcttcctttt taggatctgc tccgtactgc tccaaatcaa tcccatttga
     7741 cactgcaaaa ataggtgact tcactccata actctcaatc aaagacttag aatatagggt
     7801 aggggtaatg atagcatctg ccttattgta aaagtgacaa aggtattttt taaaccaagg
     7861 agataataga tttgaaaaaa taaaagaatt tctaaaatct tcttctgtag aatgcccatg
     7921 catgataacc ttcttaccag ctttttgtgc ttttatcatc agcagccaac tttttaaacc
     7981 ataggtattg agatgaacca aatcataagt ttctcttgga ttagtcgtaa aatgttgacc
     8041 aacaagtgac aaggctttag cctgatgctt aatcgctcga ccaattcctg attttcttag
     8101 ataattttct gcttctaaat acaataagac tttcataagt tctattatag ctcattttat
     8161 agtatttttc actaagacat gcaaaaatca gccttagggc tgattttagt attgaagaaa
     8221 cagtctattg tgatactttt tgttagatgg tgctcataag tcacagttac ttagttgtcc
     8281 cacgtttttt aataccatga ttcaaaagaa tttctttttc ttccaactct tctttgttca
     8341 tgattttagt caacatccgc atgctaacag cacctaagtc ataaacaggt tgactgatag
     8401 aactcaaatt gggacgagtg tattgaacca ctggtgaatc gttgctggtg atgatttcaa
     8461 agtcctctgg tacgcgttta cctgcttcaa acaagccgtt taaaaggcct gctgccaatt
     8521 catcttcagc cacataagcc gctgttgctc ctgagttaat gacgcgctgc gccaattcaa
     8581 atccttcttt ataagaatag ttcgcttcaa aaacaagacc ttctttgaag tcaagcttat
     8641 tgtgcttcaa tccttctttg taccctgcta agcgcacttt accattgata tcatcaatga
     8701 gtggtcctga cacaaaagcg atacacttat gattttcagc taaaatatca acaacgtttg
     8761 acaccgcagc tctatagtca atgttgacgc ttggtaattg atgatcaaga tctacagttc
     8821 ctgccaaaac aactggagta cgagagcgtg aaaattcggc ccggattttt tctgtcaagt
     8881 gatgccccat aaaaataata ccatccactt gcttggcaaa aagggtattg acaacattaa
     8941 cctccttgtc atcatcttca tcactggagg caagcacaat attatatttg tacatagcgg
     9001 cgatatcgtc aataccctta gctaagatag aaaaataact atttgcaata tttggaatca
     9061 caacgccaac ggttgttgtc tttttgctgg cgagaccacg cgcgacagca ttgggacgat
     9121 agtcaaggcg atcaataact tctaaaactt tcttacgtgt attttcctta acatttttat
     9181 tgccattaac aacacgacta acggttgcca ttgaaacacc agcttcacgg gcaacatcat
     9241 aaattgtaat ggtatcatct gtattcattt tttatcttcc tttctatttg aaaatgacgc
     9301 tttcaaaaag tattttagca tgatttgtaa ccactttcaa gtgttatagg ttaatttttg
     9361 aaaaagtttt caaacattaa ctcgaagctt gattttttaa gctttttttg aaaaaatagt
     9421 aagtagaaag aaggttagcc tatgacaaaa ttagaccaaa tacgtttgta tcttgaccaa
     9481 aagggagctg aattggcgat tttctcagat cctgttacga ttaactattt aactggattc
     9541 ttctgtgacc cacatgaaag acaactgttc ttgtttgtct accatgattt agcccctgtg
     9601 ctttttgtac ctgcccttga ggtggccaga gctagccagg ccatatcatt tcctgtgttt
     9661 ggttatgttg actctgaaaa tccttgggaa aagatcaagg ccgttttacc aaatacagca
     9721 gccaaaacca tttatgctga atttgaccac cttaacgtca ataagttcca tggcttgcag
     9781 actatctttt caggacaatt taacaatcta accccttatg tccaaggcat gcgcctcgtc
     9841 aaatcagctg atgaaatcaa taaaatgatg attgccgggc agttcgctga taaggctgtt
     9901 caagttggtt ttgacaatat ttccttagat gctaccgaaa cagacgtcat cgctcaaatt
     9961 gagtttgaaa tgaaaaaaca aggcattcat aaaatgagct ttgacactat ggtcttaact
    10021 ggaaataatg cagccaatcc ccatggcatt cctggaacaa ataacattga aaacaatgcc
    10081 ctacttctct ttgacttagg tgttgagacc ttaggctaca ccagtgatat gaccagaact
    10141 gtggctgttg gtcagccaga ccaatttaaa atcgatatct acaatctctg cctagaggca
    10201 caactagcgg ctattgactt tatcaaacca ggtgtaacag ctgctcaagt agatgctgct
    10261 gctcgtcaag tgattgaaaa ggctggatat ggtgagtact tcaaccaccg cttgggacat
    10321 ggtatcggca tggatgtcca cgaatttccc tccattatgg ctggcaatga cttggtcctt
    10381 gaagaaggta tgtgcttctc tgttgaacct ggtatttaca ttccaggaaa ggtcggtgtg
    10441 cgcatcgaag actgtggcca tgtcactaaa aatggctttg aagtctttac ccatactcca
    10501 aaagagttgc tttattttga aggctaagcc cctaccatct ggttaaacaa accctcgcga
    10561 aaggaaggta ttcgtatgga tcaaaccatt catcaccaaa tacagcaagc actacacttt
    10621 aggacagccg ttcgtgttta taaggaagaa aagatttctg atgaggattt agcccttatc
    10681 cttgatgctg cttggttaag cccttcttct gttggcttag aaggctggcg ctttgtcgtt
    10741 ttagacaaca agcctattaa agaagaaatc aagccctttg cctggggggc ccagtatcaa
    10801 ctggagacag ctagttactt tattctttta atagccgaaa aacatgcaag atacgatagc
    10861 cctgctatca aaaatagcct tttacgacgt ggtatcaaag aaggtgatgg tctcaacagc
    10921 cgcctaaaac tctatgaatc tttccaaaaa gaggacatgg atatggcaga taatcctcgg
    10981 gcactctttg attggacagc taaacaaacc tatatcgctc ttggtaatat gatgatgaca
    11041 gctgctcttt tgggcattga tacttgccct attgaaggct ttcattatga taaggtcaat
    11101 catatcctag ctaagcataa tgtgattgat ttagaaaaag aaggcattgc tagcatgtta
    11161 tccctaggct atcgtttgcg agatcccaaa catgctcaag ttcgtaagcc taaagaagaa
    11221 gtgatttcag tcgttaaata aggagattaa aatgaaagca ttacatacct gtatccgcgt
    11281 caaagacctt gaccagtcgg ttgcttttta cacaagcgcc ttccctttta aggaaaacta
    11341 tcgtaaagat tttccagata gtcaatttac tcttgtttat ctggctttag aaggagaaag
    11401 ttatgaatta gaattaacct acaattatgg tcatggcgac tacgacttag gaaatggcta
    11461 tggtcatatt gcccttggct ctgaacattt tgaagcagac cataaaaaac atcgacaagc
    11521 aggttttcca gttaccgata tcaaagaact ggctgacaaa tctgcccgct attatttcat
    11581 tcaggatcca gatggctaca aaattgaagt cattgattta aacaactaat actattaaca
    11641 acagaagctt taaagcttct gttgttttat tttttaacct gacgattggg acaatctcat
    11701 tattaacaga gttttgaaat atctcagctt ttgtgttaca attgccctaa aattctattt
    11761 gaaagaaaag tctatgacac tactatctat cattgtcccc tgctttaatg aagaagcaaa
    11821 cattctccct tattttgaag aaatgcatca actagaaacg tccatgtcca accaacttgc
    11881 ttttgaatac atttttattg atgatggttc taaggataac accttaggta ttttgcgtga
    11941 gctagctgct cgctttccaa acgtgcatta tctgtctttt tcacgccatt ttggcaagga
    12001 agctggactc ttagctggac taaaagaagc caaaggcaat tacattactg tgatggatgt
    12061 ggatctgcaa gatccacccg aacttttgcc agttatgtac gctaagctaa aagaaggtta
    12121 tgacatcgtt ggcaccaggc gccaaaatag acaaggagaa ccactaattc gttcaatgtg
    12181 ttcgaatcta ttttatggac tgatcaaaca cttatcagat actgaaatgg tcaatggagt
    12241 tcgggattat cggttaatga ccagacaagt cgttgatagc attcttgagt tgggagaggt
    12301 taatcgtttt tcaaaaggga tcttttcgtg ggttggttat cgtatcacct atcttagttt
    12361 tgaaaatcaa aaacgcaaat atggaaaaag tcgttggcat ttttgggagt tgctccgata
    12421 ttctttagat ggctttatca acttttcaga aatgccgtta accattgcta cctggacagg
    12481 gactttcagc tttttgattt ctattttcgc catcttattt atcattatca gaaagatact
    12541 ctttggtgat cctgtctctg gttgggccag cactgtctct attattttat tcatgggagg
    12601 cattcagctc ttttgcatgg gtattattgg aaaatatatt tcaaaaatat tccttgaaac
    12661 taaaaaaagg cctctctata ttatcaaaga aaaacattaa attaaaacat ttttctcatc
    12721 aatcgtttcc tactccttct gtgcgcgaag ctttcttttt aagcccgtta taccaaatga
    12781 taatgacctt tccaaaatag tatcaccttc cttaacactt taagtagaaa aggaactatt
    12841 aggttgagcc tttttgcaaa tcctagcgac taatgttata atcgtcatac tattgaaaaa
    12901 ggagtttttt atggagtgga ttaaattaat cggtattgtg attatcgtat tagggtttat
    12961 tttaaaattt gatgctatcg ctaccgtagt tgttgcagga cttgttaccg cgctggtttc
    13021 aggaatttcg tttgtcgatt ttctagatat tttaggaaaa gaatttacca atcaacgttt
    13081 gctaaccatt ttcttcatca ctttaccgct tatcggcttg tcagaaactt atgggctgaa
    13141 acaccgagct actcagttga ttcaacgtgt tcaatccctt accgtcggcc gtttattgac
    13201 tctctacctt attattcgag aattagcagg tctcttttcg attcgactag ggggacatcc
    13261 acagttcgtt cgccccttga ttcaacctat gggagaagct gctgctaaag ccaacattgg
    13321 agaagagttg accgatacag aaaaagatga catcaaagct atggcagctg ccaatgaaaa
    13381 ctttggcaat ttctttgccc aaaatacctt tgttggcgca ggaggtgtcc tacttatcgc
    13441 tggaacttta gagcagcttg gctatgatgg taaccaagct aaaattgcat tttcttctat
    13501 tttaattgct attatctcta ttattatagt tgctatttac aattacctct ttgagaaaaa
    13561 aatggaacgt caacatcaga aaggagataa ctaatggcta acattgcaaa ccttgtttta
    13621 gaaacgatat atatccttat cggcttgcaa ctgtttcaca cagcctactg cacctttaaa
    13681 gataaaacca accctgtcta ttttgggaca gctctgttct ggggattgct gggtgttacc
    13741 ttcgttggcg gtgccttttt gcctaataaa gttatcggtt ttatcgtgat tgtcctagct
    13801 cttttaacct tgtttaagca agttcgtatt ggaacattac cagcctttaa tgaacaaaaa
    13861 gctgaagaaa gtgctcaccg cattggtaac tggattttct taccagttat gttaatggct
    13921 atgatttctc tacttcttgc cttgatcctt cctgatttca gtaaaagtgc cattgggatt
    13981 gctggtatct tagccactat tgctatttta ataatcacta agcaaaaacc atctgctctt
    14041 ttagctgaaa ataatcggat gaaccaacaa gtgtccacaa gcggtatttt gccacagctc
    14101 ttaggagctt taggagctat ttttgcagct gctggtgttg gtgatgtgat tgcttctctc
    14161 attcgggaga ttgtacctgc tgatagccgc ttctttggcg ttctcgctta tgtgcttggc
    14221 atggttattt ttactatgat tatgggaaac gcttttgctg cctttaccgt tattacaacc
    14281 ggtatcggtg ttccttttgt ttttgcttta ggagctgacc ctattattgc cggtgcttta
    14341 gctatgactg ctggtttttg tggtacctta ttaacaccaa tggcagcaaa ctttaatgcc
    14401 ttgcctgttg ctttgatgga gatcaaagat cgaaatgcag ttatcaaaaa gcaagctcct
    14461 atcgcccttg ttttaattat tactcacatt gccttaatgt atttacttgc ttattattaa
    14521 cttttttgct aagttagtag cgtcagttat tcattgaaag gacattatta tgaaaattct
    14581 tgtaacaggc tttgatccct ttggcggcga agctattaat cctgcccttg aagctatcaa
    14641 gaaattgcca gcaaccattc atggagcaga aatcaaatgt attgaagttc caacggtttt
    14701 tcaaaaatct gccgatgtgc tccagcagca tatcgaaagc tttcaacctg atgcagtcct
    14761 ttgtattggg caagctggtg gccggactgg actaacgcca gaacgcgttg ccattaatca
    14821 agacgatgct cgcattcctg ataacgaagg gaatcagcct attgatacac ctattcgtgc
    14881 agatggtaaa gcagcttatt tttcaacctt gccaatcaaa gcgatggttg ctgccattca
    14941 tcaggctggg cttcctgctt ctgtttctaa tacagctggt acctttgttt gcaatcattt
    15001 gatgtatcaa gccctttact tagtggataa atattgtcca aatgccaaag ctgggtttat
    15061 gcatattccc tttatgatgg aacaggttgt tgataaacct aatacagctg ccatgaacct
    15121 cgatgatatt acaagaggaa ttgaggctgc tatttttgcc attgtcgatt tcaaagatcg
    15181 ttccgattta aaacgtgtag ggggcgctac tcactgactg tgacgctact aaacctattt
    15241 taaaaaaaca gagatatgaa ctaactctgt tttttttgtg ctaaaaatga aagacctagg
    15301 gaaacttttc atcggtcttt ctcaattgtc atcttaatct aatactactt ctaacatcag
    15361 cgggtatagt ttgccagtaa ttaagaaacg ttgttgatct aaatgagcaa tcccattcaa
    15421 aacattaagg tcagggtaat gggacttatc aagatttaag gcttttaaca aaggactaat
    15481 atcataggtg gctaccacct ttccagaatc aggttggagt ttgacaatag tattggtttg
    15541 ccaaatattg gcatagagat aaccatctac atactctaat tcgttaagca ttgagatagg
    15601 gacactttct atagcaacta gtacggtatc caataaagca aaatctttgg ggtctcgctt
    15661 ttgcaaaaaa gcatttccac tagtcatcca aagacactgg ttttccttat cataggctaa
    15721 tccccagcca tctccttcaa atggataggc ccctaaacaa ttgcaggtag ccttatcaaa
    15781 cttgtaggct acaccctctt tataggttag taaccaaaaa taatcctcaa caactgttag
    15841 cccttctgca aaaactgtat ctggaaaagc tattttttct gaaaagatct cttgagtaag
    15901 gtcatacacc cctacttttg agaaaccata acgaccggca ctaagtaata tatgattgtt
    15961 gttgagttgt tctaatccct gcgtgtataa gttgctatca taagaataag ttcgtaacaa
    16021 acgaacttgt cctttagtta tcataatact cattcacctt accttgcatt gtagtgtttc
    16081 atttgttttt taatatctct ttcctgatca cggcgtttaa tggtttcgcg tttgtcatac
    16141 tcgtgtttcc ctttagctag accaatcaga actttagcaa agccatcctt gagataaact
    16201 ttgagaggaa ccaaagtcat accagatcct ttaagttcat ttgctagatg cgtaatctca
    16261 cgttttttga gcaacagttt gcgggtccgt tcaggatcag cgttccaaat attaccttgt
    16321 tcaaaaggtg caatatgcac gttgaccaac cacgcttccc cattcttaat ttgggcaaag
    16381 ccatctttta gttgaatacg agctgcacga acacttttaa tctcagttcc cgttaagaca
    16441 atccctgctt caacggtttc aacaatgtga taatcatgtc tagccttttt attttgcgcc
    16501 agtatatgac cttcaccttt tgccatagtt aactcctttt acgactcttc ttttttgctt
    16561 gttctttgta aaatggtttt ttagaccctt ttttagtttt acccttggtt tttgccttgg
    16621 ctacttcttt aggttctttt ttctttgtcc ctttagatga ttttgaggat ttacggcgat
    16681 ctcgtcgact agctttatcc gacatcttga ttttttcaac cacatcaaag tcgctaggta
    16741 aatactcaaa gtcaatgtca ccagtttcct tgtcagcctt aaccaatttc acacgaatag
    16801 gttgaccaac tttaaagact ttacctgatt tttcaccttg aaggcttagc gttctttcat
    16861 taaagtgata gtattccggt aagctagtga tatgaaccaa accttcaatc gtatttggca
    16921 attctacaaa aaaaccaaat ttaacgacac tggaaacgat accgtcaaat tcttcgccga
    16981 catactctgc catatactca gcttttttca tggcttcaac cacgcgttca gcatcaatag
    17041 cacgacgctc taactgtgaa gaagatgttg ccagctctgg aatgatctga gcaaaatggt
    17101 cgcgcttttc ttgactaggt tgattgtact cacgaaccat gcggtgaacc aacaagtcag
    17161 ggtaacgacg aatcggactg gtaaagtgag tgtaatattc tgcggccaaa ccgtaatgcc
    17221 catgattatg ttcagaatat cttgcttgtt gcatggaacg tagaagcatc atgttgagca
    17281 cttctgctcc tggttgacct tcgacttttg ccataaaggc ttgcaaggct tcctgagaaa
    17341 tcttgttggc tgttccttga atgtgaatac caaaggtgct agcgtagtca ataaattgtt
    17401 gaagtttttc aacctttggt tcttcgtgaa tacggtagat aaacggtaac ttagcttttg
    17461 caaaatgttc tgccacacac tcattggctg ctagcataaa ggattcaatc atccgctctg
    17521 caattcccct ttgacgaagc accacatcaa ccggcattcc tttgtcatta acaataactt
    17581 tagcttcttg cgtatcaaaa ttcaaggcac ctcgttttga ccgcatcgct tccaaaatcc
    17641 tatgtaaggt taccataagg gtcacatcat cagcaatgct agcgaattct tggagcgctt
    17701 cttcatctcc tgcaatcatg tcattgaccg tactatacgt cattcggtaa gttgtcttaa
    17761 tcactgattg acagatttga taattgacca catacccctg cgggttaatt tccattaagg
    17821 ctgactgggt caaacgatca acgttagggt tcaaagagca gatgccattt gacaaacgct
    17881 ctggtaacat cggaaccaca cgatcggtga catagacaga agtgccacgg gcgatagctt
    17941 ccttatcaag ggaagatcct tctgtcacat aatatgagac atccgcaata tgtaccccaa
    18001 gttcatagtt accgttatcc aatagcttaa tatggatagc atcatctaag tctttggcgt
    18061 ccgcaccatc aatagtaatg gtggtttctt gacgcaaatc cacacggcct attaaatctt
    18121 tagcagttgg tgcttctgaa atagcattgg cctcagctaa aacttctgct gggaactctg
    18181 acacgatatc catcgattca aggacttcta ggacatcaat tccaacgtct ccttgatggc
    18241 ctacgatatc acgcacactg gctacaaaat aatcgtgccc gcgtgtcggg tatttatcaa
    18301 tatcaacctt gatgatttca gtgcctttaa gcacaacagg ctcttttttg atatagattt
    18361 tttgttgaat cttttgattt ttggacctga tataaccagc atattttggt ttgtcatcat
    18421 ctaaaataaa ggttccaaca gctgttttta aagaacggtc aacaatagca acgatcttag
    18481 cttcagccgc tgtgcctttg agacggtctg ctggcttttt aaccactact tcgacagtat
    18541 caccatcaat agcataccca acatcattac gaccgataaa catatcgtct tcattctcat
    18601 ccacatgtaa gaaaccaaag cctgctttat tggcacgaaa aacaccctga acagtaggtt
    18661 cttttttctt ttcacgctct tttctaagag ccagactgcc atcatctgaa aaccgtaaca
    18721 ggctctgact ttccattttg gaaatggttt taataaggct gggaaactgc ttagctccag
    18781 ccatctccaa ggccgcagcc aagtcgttca cattggactt gccatgctcc ttgaggtaag
    18841 tcataattct ttctttcatc atacctaatt tctatttctg ttttgtttgt tggaggatat
    18901 caatccgttt cgctgataaa aaaatgagct agactaactc tgtcaagctc actccttatt
    18961 tacttgataa aatggcaagc acaagtgcaa tcgctagcca aaaaaatact agaactgctg
    19021 tgaatcgttg catgaatgct tcaaagccac gagcttttgt acgttcaaac aaggcttctg
    19081 aaccgctgct atcaaaaaca ttgctacttg ggtttttttg aggttgcata aaaatagcaa
    19141 tcacaagcaa taccgacagt actagcaata tcgtaagtag taagttgtac atgttatttc
    19201 ctccactatt gtcatgacca ttctaacaca attcttatca agtttcaaca tgcagggtca
    19261 cttttctctc cttggggcag tatttgggaa cttttatttt ttccggatga ctgcttttat
    19321 ttttactggt tagataattg ttactgccac actcactaca ttctaaatta atttttactc
    19381 tcacacaata tccttaactt taatatattt tcgaaatata atcaaactcc atattaaatt
    19441 aacaaacaca atcaaactag tcacataaaa aacagaacgg tagcctaaca ctacagccac
    19501 atttgatccg ataaaagggc caatgacttg accaaggtta ctaaacattt gattataggc
    19561 aaatactcta gaaatacctt cttttggtgt taacttagtt agtaaagagt taatacttgg
    19621 catcaaagcg cccacaccaa acccataagc aaagcgtagt actcctaatt gaaaactggt
    19681 ctgcgctaag gcactgctaa aatacatgat aaagctataa cacaaagcgg ctaacaataa
    19741 ccgatgattg ccaaatcgat ctcctaattt tcctaagtaa gaactgctaa ataagctaga
    19801 aaaccccatg gccgaaacta ccaggcctga agtaaacatt aagttgtgag tttgaccaag
    19861 atgacgaata tacaatgata aaatgggggc cactgattga gctgaaattt gaataatcat
    19921 actagtcaca aacaaaccaa gcataatctg gggacttttt acctgtttta aaatgacttt
    19981 tgtaggtatc atctcaaagc gcctaatcgg cttaaactct tctttaacat aaacagctgt
    20041 cattaaagaa cataaaaata atatcacacc aactaataag aaaacttgtc gaattcctaa
    20101 tagctctgcc aaaatccccc ctagtaaagg accaattaaa gcgcctgctg tcactcctgt
    20161 tgctaatgtg cctaaagcat aacctgactc ctcttttggg gcttggctgg caatcaaggc
    20221 agtggcattt ggcacatagc ccgcaaagac acctgttaat aatctcaaaa tgagtaacca
    20281 aaacacatta ggaataatag ctaaaccacc catggtaaag gtcataacaa aactggctcg
    20341 cagcatcata ggttttcggc cataacgatc agccaacttc ccccaaacag gagcaaataa
    20401 agctgaagca agtgccgtca cagcaactgc cagaccagca cagtattcta ctaattctgt
    20461 cggagtacct aaattttcca catatagagc cataaaaggc ataacaagtg aaaagcttgc
    20521 cccagtaaag aagttaccaa gccaagccac ttttagattt tgtcgccagt tcactgtcgt
    20581 taccgcttta tcactaatag atcatcatct tctttccatt gggcctttga ttattataac
    20641 acatttctgc caaaaacagt gtcccataat agtgctaagt ctcatctgat agccttcatc
    20701 gtttacgtaa actacccagt aaacctctga ccagttctcg cccaattgtt ctaaccgtcg
    20761 tactaataaa cgcatctgtt gctttttcga cgactgtttt gtggggacgc ccaacagaac
    20821 gccgattagc ttttttggta gctgcttgcg ccttgatggc ttctttagct tctttttcgc
    20881 gttgtgctgt cgctatcgct tcttgggcca gtcggttgtc ttctaaaacc ttagcagcta
    20941 atttttcata agcagattca cggtcaatgg actgactata tttactggca aaaggtgagg
    21001 actgcacaag ctgctgactc tctatctctg acaaaacagc aaagctactc ttaggcggca
    21061 tgatataggc acgttcaacg atggatggtt gtcccttatc attcaaaaca gaaatcaagg
    21121 cctcaccgac ttctagttct gtaatcaccc ttgccacatc taagtcagga ttttgtcgga
    21181 aagtatccgc agcgacacga accgcctttt gttctttcgg tgtataagcg cgcaaggcat
    21241 gctgaatacg atttccaagc tgagccaaaa ccgtttctgg caaatcaagt gggttttgag
    21301 tcacaaagaa aatcccaact ccctttgaac gaataagtcg cacaatctgt tcaacttttt
    21361 ccaagaaaac tttaggggca tctttgaaga gcaagtgagc ttcatcaaaa aagaaaacca
    21421 tcttaggttt gtccaaatcc ccaacttctg gcaataattc gtacaactca gacaagagcc
    21481 aaagtaagaa ggttgtgtaa agggtaggag attgaaaaag cttagtcgct gacaaaatgt
    21541 taatggctcc atagcccgaa gcaacatcta attgcatcaa atcagccaca tctaaagcag
    21601 gctctccaaa aaattggtgg gccccttctt gttctaatgt caagagactt ctttggatag
    21661 ccccgataga ttgcttggcg atattaccgt aatggctgga gtagtctgag gcatgatcac
    21721 caacttcttt taagatagcc tgcaagtctt tcaaatcaat caaaagccaa cctttctcgt
    21781 cggcgatttt aaagacgatg tttaagacac ctgtctgggt atcattaaga ttcaataaac
    21841 gcgacaacat catcggtccc atttcagaaa ttgttgtccg taagggttga ccgttttgac
    21901 caaaaacatc tcacattctt acaggaaagg cctgaggctg gtaatcactt accccgattg
    21961 tggctagacg cgcagccaat ttatcagtca cctctcctgc tttagtaaga ttagacaggt
    22021 ctcctttgat atctgccaaa aagactggca caccagctaa acttaattgc tctgctagca
    22081 cttttaaggt cacagtttta cctgttccag tcgctccagc aatcaaaccg tgacgattta
    22141 gcatccctaa ttgtaaggct atcggttgat tgccttttgc aattgtcatt gtagtcatag
    22201 gcttcctctt ttttgatgat catacttgtc gatatgtgtt tacccataag ttaaagtgtt
    22261 tagaagggtc tcgctcttaa tactattata acatataacc cttgatgcgc taatttaaaa
    22321 gggaccagct agttttagac agaaatagct tgattttgac agctatgata cgaatctctc
    22381 agcttagcta cctcggattg gctaatgaca acaacgcaga ttgtacttgc tttattaacg
    22441 tttccatgtc tccattatta tcaatcacta gactggcata gggctttttt tcctctattg
    22501 gtaactgact ggctattcgc tgccttgctt ttcctttgtc taaacgattt ctagccatta
    22561 agcgctgcaa ttgtgtctga gcatctacat aaaccagcca aatcgcatca aaccagtctt
    22621 ggtagcccaa ttccattaaa aggggaatat ccatgaaaaa aatggcttgg ctctgtgcta
    22681 agtggtcacg cttagccgcc aattcttcct taatgatttg attttgaatg gctgaggatg
    22741 ttgccatatt atctgggttt gaaaaaagca tttctgacag ctttgtgcga tctaactcac
    22801 catctgcttt taaaatctga ttcccaaaag cttctctaag agcctcgtaa agacgaccgc
    22861 ctttttcttg caagtcatgg accacttgat ccgcatcaat cacctgataa ccagcttttc
    22921 taatgacctt aaccacagtc gattttcctg atgcaatgcc tcctgtgatg ccaataatca
    22981 tggtcttttt ttctggcatt ttggacaaat gtgcgtcccc cttcctccaa cttttaattt
    23041 gacaatagcc tgtccacaac gaggacacgg tttcccagtt tgaccataaa cctgcaaata
    23101 gtcctgcatg gtgccatcag ctcccaaagt attacggtaa gtacggacgg tcgaaccgcc
    23161 cttttcaatt cctaaagcta ggattcgtat ggtttcatca tgcagccgtt ttatctccgc
    23221 cttattcaac ctagaagacg cagtttctgg atgaacctta gcagcccaaa gtacctcgtc
    23281 cacataaata ttccctaaac cagcaaccaa ggtctggtct aacaaatgtg gttttatggt
    23341 ttttttggag gatagcagaa cagcctcaaa ggtttttaac ttaaaggtct ctttctttgg
    23401 ttcagggcct agttttcgtt tggcaaaaaa cgctgataat tgagattttg ctatcaaatc
    23461 aaaggttcca aatttacgca catcttggta aaccaaggtc gaaccatttt tcaattcaaa
    23521 aaagacatga aagtgtttgt tatcagggac ctcatctgga aaaagcaaat atttgccttc
    23581 catccgcaaa tgtgatacca acactaattg ccccaaatca attaataaat attttccccg
    23641 acggccaact gactgaatga tttgaccagg tagggtcagg gcaaacgtct ctaagtcggt
    23701 tttaaccatt tttggcactt taagcgtaac agccacaatt tcttggccaa gcactaaagc
    23761 cttaagccct cgtcggaccg tttcaacttc tggtaattct ggcataatcc gttatttaaa
    23821 ggacagctag accctttgct gctacaaaga ataaactcag cataaaaaag tcactcaata
    23881 gactcaggtc taggatactg actgcgtttc aaaaaacaca gctgtccttc tcctttctta
    23941 tttcttattt tacgaacaca tctgatagaa agcaactcat aaatctgcct cagaccagtc
    24001 ctcatccccc ttacctccca gcactatttg gcggtaatgt tccttataac tataatacaa
    24061 tgagtcctct ccaagatact taaaaatctg caaggcctgc cgcatgtcct cttctccaga
    24121 aatttctttc tgctttaatt tataataccc atgcacatat aagaaaacag tcttttcata
    24181 aaaattgagc tcgtctcgca gcaaaagatc aattttgtta atcaaatagc gactatgttc
    24241 aaagcaagaa tggtcaatac tgataatgag acaattaatg gataactgag tcactaacat
    24301 tttattggtt ttattttgtt ccgaataagc aaaagatgct accatttcct tagtcaataa
    24361 aaatagggta ttgtaattca tgaagcgcga gcaattcccc agaagaatga tttcataata
    24421 tccccactgt tccactttaa ataaataatc tgtgaggcga gtcaattctt cttgactagg
    24481 tgcaattgag gagtcaatag aaaaaagaat agctttaatc atcgttcgtt cataatcttt
    24541 atgggcataa tccttcaaca gtttggtcaa tttaaccacg tttttctcag cataacattt
    24601 tctcgcctga cttaagagcg tgaaaaaatg cgtatgcgtc ttggaatgag ccgaaacaaa
    24661 ttcgtcaatc gtaatattca gtttatccaa aagattaagc aagcgactgc aggtgatttc
    24721 tgattcccct cgttcaaatc ttgaaatttg tgacttggac aggtattcat ctgctaaaaa
    24781 agaaatgcta acctgcttac ccttacgtaa tcgccttaag gtttttccga gttctttttc
    24841 catttttccc actttcacaa caaaaaatta aaatctgcta aatccattat ataatacaag
    24901 tataaaatag aaaatcagaa aggagacagt catgaaaaaa gttaataaag ctttgctttt
    24961 tacattgatc atggatatcc tgattatcgt tggtggataa cctttcgctt aaaaacaatc
    25021 cacttttggg aaacccttat atttagtttg taacaggaaa actaatagat attaaaaaga
    25081 gtgttagcga cctagcggca gctttactct taagtgcgtt tgctgccatt gacagcaagg
    25141 tcaaagctga tgaaacagca ggggcatacc gttatgatgt gtctaaacaa aacacttact
    25201 atcaaactat cagctccatt aaccagcaac gacctggtgc cactctcgac gaatgaggtg
    25261 attattatgg aacccttact tcatttactt cccaaagtcg taccagtact tatacacttg
    25321 gtagacaaag ccaacgtatc atggttaaca gtgatattac agttacctat actcttaaag
    25381 acaatttggt agcccttcat aaggaatata aaacctttgt caaaaaaaat attacagata
    25441 aaccgatcac cagtgactac gacaaggcta aggttattta taaccattta atcaacgaat
    25501 acacttacgc cacaaaataa cttagcacca atcacaaaac cgtaagcagc atcaacaatc
    25561 atactcctaa agctctttat cgtggcaagt gtggtgtttg tcaagcttat gccgtcatgt
    25621 ttaaagatat ggcagaagct gcaggcttat cagcttggta tgtgataaaa aaggattgaa
    25681 tgagcaccat gcttgaaaca tcgttaccat tcatggtgtt aattcctacg ttgatgctac
    25741 ctggaatgat tcagcataca ccacaaggta tttccttgct ggaaaagacg tgaggaatac
    25801 tgagtaccgt ttagatagcc agtacaacca cttggctaat gctattttaa ctaccagcta
    25861 ccaaaaaggc taaactaaca acaactacat ttttcaacta gaaaggccta aacaatgacc
    25921 aaaaaacagt tttatcttat cttagctatt agcatactgt gttttattct tgccgtcagc
    25981 cctaaaccac caattcctaa acacactatt gaaaagaaaa ggactgcgat gaccataggc
    26041 cactcaaaac aaaaccctca caaaaaagaa gcccttaaac acaaaaaaaa caaaaataag
    26101 actctttttc ttccaagtgg ggacagcgct atcaaatctg ttattagcat gacagttaga
    26161 ctcctgttag atgaccaatc ttagctctcc taaaatcagt ggacactacc gtttcggtag
    26221 tgttcttttt taagctaatc tcatcaccac gctttcttca agctaaaaaa ctgatcatga
    26281 aagagcaacc ccatcaccct aacagctcac tttgcccgca ctttcttaaa aagttaggag
    26341 aaaacgatat accaattatt ttctgatccc agctccctat cattaacaag atgtgtagca
    26401 cggacctaca tacaggtaag ctagagtcat tctcgctact tcggacaaaa agaggccggt
    26461 agttccctga cctcttcttt atttatcttg taatactcct cttcttagcg agacttacta
    26521 gcacataatt cttaagcact cttatcattt agactaggaa gaacaccatc tgaatgaagc
    26581 aaatgatgcg tcagatctgc cagagtatca tctccataag taatccctgt ttagtgctgt
    26641 ttctgatgaa aatcagatga ctccttaact ttagcagtca cctgctagtc acttggatga
    26701 aaattaattt ctctcttggc ttcagccgca actggctcga ggaacaactt attgacatta
    26761 cggtcttcct ccaaatgatt aaggatagca gcatcatctt ctaacgaaag aaccttcttg
    26821 ggtaacaaaa aggggttatt tagccttggc tcagtaacga cttccttggc tgctcgtgat
    26881 agtttattat tgtcttcctc aggtatcaaa cgattaagca atcgatgcaa ttcttccggc
    26941 tatgaggcgc tcacagctac ttcagaagaa acctccaagc cttttcctgt ttgcctgtct
    27001 aaagcaaccg gcaaattatt aactaacttt ttaacctgtc ctcagcgctc atttcaacac
    27061 taggaagagc tgtcgctggt tctagccagc taccaacttc tgctggtctt accttaacat
    27121 cgctggcagg cttctccttc tcatcttcat taggtctaaa aggctcaaac cgccctgttg
    27181 atttttcatc tatgaccttt atattgtctt ttactacatg agacagtggt tcgacattta
    27241 ccatagcttc atgctcgtta aggctctggt ctcgtttgaa tttaccagga ataccaggag
    27301 tcggtgttcc aacagattga tcggcttcag taggctcttt tacggagcct tttttccata
    27361 aaactgctgg aggaataata tccgtagagc catccccata agtaatcgtg gcctgcctcc
    27421 cctttggatt aatagatact ttaatattgt ctgggaaagc cccactacct cctgtggtta
    27481 aaagggcacc cgcattttta atgagagttg tcattcgttc aataccagca acgccaatat
    27541 ggttcaagtc atctactggt aactgatcaa cagatttcat ggtgtatttc caagcttgcg
    27601 gttgaacaag aaaaacagtt cctttataca ttgtgttatg catatcatca atgactttga
    27661 aataccttgt atatttggtt tgtacattag ggttagcaac gggaacagtg ctttcaggaa
    27721 ctcctgacat cgtaaaaatc cctctagcag aagtttgaaa gccctcataa acatgaccca
    27781 taccaggaac agtctgagcg gtcaaagact taccagaacc atccaaagca atgcgaatat
    27841 ctttcatcag atacatctga ttggtatagg taaacctaac cgtgttagcc tcacctcgat
    27901 acaaaaccac ttgggagggc tgatccgaag aaaactgaga ggttgtttct tccttatagc
    27961 caactccaaa acgtctatca gacgaatgga ctgaatctgc cgcaactgta ctactcaaac
    28021 tgactagtaa agtagccgca caaccaacta ataaactgct cgttttaact ttaacatctc
    28081 ttaacatcat catgttcctt tcattatttt ttatttagga attcgtcata ctatattttc
    28141 tcatattagt ctaacaaaaa actcgtaatt ctatataaat catataaaat gacgagcttt
    28201 ggcaaagatg agtatagcag gatggaaaac agattgtttc tgaaacttca aaggtatctt
    28261 cttgtcacga actattcttt aattgaatcg gttacactaa actagtccca ttatttaaaa
    28321 acaaacttta aatattattc atttcacttt ttaagtttat taaatataga gtgattagga
    28381 gaaataagac gacctaatga taaaatcatt cctattgtat agcaaacaac agtaaggtgt
    28441 aaataaaagt aaattgatac ctctgatata ctcgtcaaac atcctattat tataataaaa
    28501 gcaattaagg taggaataag aattgtacac ttaataaata accaaaattg cttaacaact
    28561 tgataccatg tgagcacttc tgtcgtttgt ctttgtttgt agacaaaaac gaataaatca
    28621 aggataaaac tccaacagat aagttgtata tttttcatta atggtaaatc gtagaaacta
    28681 cctatactaa atagaatcac tgcagaaata ataacaatac ctaaaaatct taatatatta
    28741 cgcatatctt cacctcctct actctatcgg tagcaaatat aaccgaacaa attattattc
    28801 ctgttatcag agacagttat aactttttta accaattttc aatacgcatt ttgcttttaa
    28861 ctctttagtc tctaaagtta aatatcataa gtactgatat tgtataagtc atccattttc
    28921 cccttaaatg tgattgcatg atagctcagt agaattaatc ttaatttctg gtattttttt
    28981 ccacaccaag tatctataac gcaaatatag ataaacaata agtataaaat aaataaagat
    29041 cacaataagg gatatacctc ctagtacagc agcccaaata ggataagggt gcctaaagtt
    29101 gtaggctaca ctcaagatga taagggtaaa agggacaatg taacctccca gcttttcaac
    29161 attttctaga aatatcatct ttctatcaga tagattaaaa ataatatcta aagttttcat
    29221 accactcctc tactacttat acatcagtga tagatagtca tttatatatt tagtgaggcc
    29281 agataatatt tgtagcagca ccagctgctc cacacaaaat ataaccttgc caagggataa
    29341 atacgcctgt ctgagcacaa actgtcactc cctgcgcagc acctgccatc cctgtcaaaa
    29401 agatatttgc tccgtctttt ccgcctccat ttatgatagc cagaccattt tttagcactt
    29461 ccatattttt gaagtctttt tcattttaat ttcactcttt tgtattttaa aaagctaaga
    29521 gtgatatcta aattcattgg cataatcact attttctttt atcgataaaa acaaataatg
    29581 acgctaccaa agctacgata gataacatgt ttaccgattt ttccgaaagg gataattgat
    29641 tgaaaattaa aaacactaaa tatggtatag atttatcaac atttttttta tgaatggcat
    29701 caacaatgat taaaaacatt atagacgcat tcataataat aaaaatcgta tagatcattt
    29761 aatttgctgt atatcccaaa tatgctccac caactgtaaa tcctacaaca catccacctg
    29821 ccaatactgg atgtagcagt ttacaaaatt tcaatccaga agctaagcct ccaagaccac
    29881 caattacagc atctcctgga gcgtttcctc cacttatact agccatgtca ttaattgtta
    29941 attccttcat tgttgtcatc ctttctttcc tctagaatcc gcctgtagct cctgttacac
    30001 cagcccaaag agtaatagct gttttagctc caatataacc acaggctaca ccgcaaactg
    30061 gaaaacctat agcagctcca gcactacctg cagcgataac cccactgaca tttgcctgcc
    30121 aattattctt accaccctca accttggcaa gcttttctat agtcatttgg tgaaatgttt
    30181 ccagtttctt tatctccata tcgaataact tcttttcata attcttaaat ttgtctcgtt
    30241 gcaacctcga ctagtacaga atatcataaa gaacagtatc atggtttcaa aatcttaaaa
    30301 ggctgttttt catcatgaaa tgtcttttta tcctctctac acttacgctg tgataatagt
    30361 taattaatta agaagtttaa atgataccat tcatgctttt ataaatacct tttaagattt
    30421 ttgatggtag tgtaaaatat cttgtgtaaa cacacaaaaa ggaataaatc ttgtatagta
    30481 gagttacgac acttcactag aaagagattc attcccatga ctcagtttac cacagaatta
    30541 cttaacttcc tagcacaaaa acaagatatt gatgaattct ttcgctcctc tttagaaata
    30601 gctatgaatg acctcttgta agttgaacta tcagcttttc ttggttatga accttatgaa
    30661 aaagaaggtt acaacacagg taatagccgt aatgggactt attctcgtca gtttgaaaca
    30721 aagtatggct tagtcaattt aatcatccca agagatcgaa acggcgagtt ttcaccagtt
    30781 ttattaccat cttatgctag acgagatgac cacttggaag agatggtgat caaactctat
    30841 cagactggcg ttacgacacg cgaaatcagt gacattattg agcgcatgta tggtcaccac
    30901 ttgtttctga gtggaagcct cgttataaaa aggtcatggc atcacttgaa acgacggaaa
    30961 atctccttac tttctatcaa ttcccacatc acatttggtc tagcatttac tctacaaact
    31021 tgattgaatc actcaataaa gaaattaagc gacaaaacaa gaagagagtg gttttcccaa
    31081 atgaagaagc cttagaacga tgtcttgtaa gtattttcga ggactataat attaagttcg
    31141 gagctcgtat tcataaagga ttcggagcat gctttgacac acttgatagt ttatttgact
    31201 aatattcaaa aactctactc ttgtgtttac acaacatttt aatattatta atttgtaata
    31261 gtacttagta agacataaac aaatatcaca attaaaatta ctttacttgc attttctctt
    31321 acctctttat ccttcaaaaa aatttgggaa agtattagac aaattaaacc gagtattata
    31381 actataatca tatcattgat aagctgcaat tccagatgct acacatacaa atgctgccgc
    31441 acctccagtt attggacctc ctgctgcagc tataagcatc ccacctaagc accctccgat
    31501 agcagatcca atatttcctt ttccaccaga aatatttact aattcttcaa actgtaattc
    31561 taaaaaatta tccatttttc acctcaaaat tattttccat taaataacat accaccaacg
    31621 caagttaatc cacccgcaat agcacctaca tgtgcacctg caaacgcacc tgcaactcct
    31681 ccaacaccta aagtagccat acctgctcca acaccacctg caatagcacc tgaagtaata
    31741 ccaccaatta aatgattttt acaatctgta gcactataac ctccaataat atggaacaac
    31801 tcttcttttt gtatttcttc tgcaaatttt atcataactt taaaaacctt tctaaaatgt
    31861 tatattcatc ttgttgcaac tttgacaaac taaatatagc atattattat aaaaattttt
    31921 ttctatgtcg tgaatggttg tataaacatc tcaaataaac tttttaacat attagagact
    31981 gtcaataatg ttgtgtaaac acaagagtag agtttttgaa tattagtcaa ataagctatc
    32041 aagtgtgtca aaacatactc cgaatccttt atgaatacga gctccgaact taatattata
    32101 gtcttcgaaa atacttacaa gacatcgttc tcttttagga tatatgatat ctatctatat
    32161 taactattac ctcaagagat actttctaaa aactcaaatt attagtggga aaaacttaga
    32221 ttataaatac aaatgtcagg tttattttat cataaatcat acttttttaa atctgagcaa
    32281 gtatatgacc ttctaaacga aatacgtatg cgttatcctc atgctcatat tattctaatc
    32341 ggaaatcata ttaattacga ggaaatattt aaaaatcatt atcgagtttt tggtgttatt
    32401 gacacaacaa gtcataaatc attaaagtcc attcgagatc aaattcaact ttacttagac
    32461 gaactttaca attcgaataa tggataggca cttcatcaat tcttttagga aatgattctt
    32521 gtcacccctt ccaagtctat tgccacagtt aggttcaact tgcctaagtc atgcatggct
    32581 aggtggcaat tcgtcataac tctaaaacaa atgtttgatg tctgctagta tcaattggaa
    32641 agaaaatcct gttaacattt aacaaaatta ttcagactta atcagaaaaa ttggaagcaa
    32701 aaaaagagag cataagctct cgaaacatcg tctttcaaaa atttttttaa caagccaatc
    32761 tccaaaaata ctccaactgt cctagagagt tcttaatgcc ccatagcaaa gctatcacta
    32821 aaatattcct ctaacatcag gcgatgtttg gctgagacac tctctaactc tgctatctcc
    32881 tcatgagaga aaaactgtaa cttgagcgtt tcctcattat gaaagttatc aatagccatg
    32941 tcagaaacag ccgttagttc atagataaag acaatggtct gaacagcatc accgttggga
    33001 taaacttcct caaaatgagt gtaaacattc agtaagcgaa cagcttcaac ctcaattctg
    33061 gtttcctcta agaactcacg tttgcaagtc tctaaagagc tctcacccag ttccatagtg
    33121 ccaccaggaa tagcccaggt tttcttatca ccacgcaact gcatcagcac cttgctgtca
    33181 tcattggtca aaatcccacc agcaaagtta agaataatct tatcatgccc aactttggag
    33241 cggatataag aaatgtagtc atgtggcata tgatctcgct ttactatgtt agtattcttt
    33301 ctcattatag ccaaaatcag ctaaatcaag ctttttatcc cgccagtttt tcttgacttt
    33361 gacccacgtt tctaagtaga ccttgtcacc taacatgagt tcaatatcac ggcgcgccat
    33421 ttttccgatt tttttgagca tggctccttg ttttccaatg atgatgcctt tttggctatc
    33481 gcgctccacc ataatggttg cacggatatg cactttatca gtctcttcat ctcgcttcat
    33541 ggattcgaca acaacagcta cggaatgtgg aacctcttgt tgcgtcaaat gcagtacctt
    33601 ctcacgaacc atttctgaca caaggaaacg ttctggatga tcagtaatct gatcttctgg
    33661 aaaatattgg aaaccttctt caagattatc agttaataac ttgattaggg ttggcacatt
    33721 attaccttct agggcagaaa ttgggaccac ttctttaaaa tccatttggc tacggaagtc
    33781 atcaatctgt tccaaaagtt ggtctggatg aaccttatca attttgttga taactaaaat
    33841 aacaggaatc ttagctgctt ttagccgctc gataatcatg tcgtcaccct taccacgctt
    33901 ttcatcggca ggaaccatga aaagaaccgt ctcaacttca cgtaaagtac tataagcaga
    33961 ttcaaccata aaatcaccga gggcggtctt tggtttatga atacctggcg tatcaataaa
    34021 gacaatttgt tctgtttctg tggtgtaaat gcccataatt ttattacggg tggtctgagc
    34081 cttgtcactc atgatggcaa ttttttgccc catgacgtga tttaaaaagg tggatttgcc
    34141 aacatttgga cgcccaagaa tggctacaaa gcctgattta aacatagata attacgggcc
    34201 ttaacggtag ggcttcagat caaacttgtc actaagctta accgtcttgt cctttcctta
    34261 ttctcctatg ccatcatcac ataggatagc ccattccttt ctttttaatg aacgaaaata
    34321 ttccaaattt taggaataaa aataataagt cctgtcaaga cagcatagcc agaaatcatc
    34381 aaaacagcac ctgctgccat atccttagca tttttagcta gcatagaaaa gtgatagtca
    34441 ctagccaaat caactacatt ttcaatagca gaattgacaa tttctaaggt aatgaccaaa
    34501 aaaatggcta gaagtaaaaa taaccattcg atggctgaaa tgctaaaaaa taaaccagca
    34561 acacaagcta aacaggcaga caaaaggtga cttctgagat tgcgttcttc cttaaaagct
    34621 gtgaaaaccc ctgtcaaggc aaactccaag cttgaggtaa tggttctgtt tttccatttc
    34681 cgtttggtgg tattattgtc gtgtaaggcc ataagcagtc aaaatctctt cctgtaaggt
    34741 aaacatctct ttttcttctt caagggtgta gtgatcatac ccattaatat gtaagaatcc
    34801 atgaacagct aaaaatccca tttcacgctc aaaagagtgc ccatattctt gggactgctc
    34861 acgcgccttg tcaatagaaa taaacaattc gccaatataa gcatcaaact ctgccatcat
    34921 ctctgccaaa ctaggatcag cagccaaatc ctcttgacta aataaaatag gcgtttctgg
    34981 cttgtattct agagaaatca catctgttgg acgatcagta tctcggtatt ctaagttgag
    35041 ttcatgactt ctttcattgg tcacaaaggt cacagacatt tctttttctt ctttgcccgt
    35101 cttttgagca gcaaaattga gcaaatcaag tgtttgctcc ataatctctt gcgaaacttg
    35161 tcccgtttcg tcaatcatct cgatatacat aaggttaatt gttagggaag ggctgcccac
    35221 ctcatttggt atgttgggca cccattatta tctgacagat aatttccctt atcctttcaa
    35281 tcagcatttg ttatttaccc attataccac aagcccctta aaaatgggaa tgctaggtaa
    35341 atcagggcct atttggttag aattgcctcc acacgttttt gcaagatagg taataaatcc
    35401 tgctcaaacc aggggttctt agctaaccac aattggtttc ttggagaagg atgaacaagt
    35461 ggaaaatagt ctggcaagta atcctcaaag tgacggactg tttcagttaa ggttttgtaa
    35521 gccttgttac caaggtaaaa gtcctgagca tagcgaccaa ccaaaatcgt caattcaact
    35581 tctggcatca atgctcttaa tggcgggtgc cacttagccg caaagccttc tctaggtggt
    35641 aagtcaccgg attttccctt accaggataa tagaaatcca tagggataat gccaaacaat
    35701 cctgagtggt aaaaggtgtc attgtccaca cctagccagt ctcgtaagcg gatgccacta
    35761 cgatcattcc agtaaagttt ggtttcttga gctactattc caggagcttg gccaacaata
    35821 ataatcctag ctgtttgagg agcatcatat aaaggaaaaa tacctctttc ggtataggag
    35881 agattagcct catctgccat aatagctttg gttaaatcat ccatagaatc ctccttaaaa
    35941 aggccatatt aaacatcatc gtaaaggtct tagtgctctt gaccgatcac agggtatttt
    36001 gtcaagcctg gctggtaatc agcttcaacg tcactagcct tgggttttag taagtccttc
    36061 gtctcctctg aggacgtttc ataagccttg ataatatcag ccacaacagg atgtcggaca
    36121 acatccttag cagataaata gacaaaatca atctgtttaa taccttgtaa tttctgagta
    36181 gcatcaatca aaccagactt gacatttcga gggaggtcaa tctgactcgt atctccattg
    36241 acaatcattt tagaattaaa accaagacgg gtcaaaaaca tcttcatttg catgatggtc
    36301 gtgttttgag cctcatctaa gataacaaaa gcgtcatcca gagtacgacc ccgcatataa
    36361 gctaacggag caatctcaat cacatctcgt tccatcaggc gtgtggtttg ttccttgcct
    36421 aaaatgtgat aaagggcatc gtaaaccggt ctgaggtaag gatccacctt ttctttcaaa
    36481 tcgcctggta aaaaacctag gctttcacca gcttctaccg caggacgcgt caaaataata
    36541 cgctttacct gtcctctttt cagagcagtg actgcaagcg taacagctaa gaaggttttc
    36601 cctgtccctg caggtcctac accaaaaacc acatcatgac gtttgacact atcaacatag
    36661 gttttttgac ctaatgtttt gactcgtatt gccttaccat agttatcttt aatgatttct
    36721 tcttcataaa gcgccataaa ttggtcaatc tgatgagatt ctgccataga taaagctgtc
    36781 accacatctg atgtgttgac caccatgcca cgacccacta gaaccagtag gcctttgatg
    36841 gtcaatcgag ccaattccac agcttcttca tcatcaccaa tcacttggac tcgctcggtt
    36901 cttgcgtgaa caataactcc taaatgagct tctattagct tcaaatgacg ctcgttgcta
    36961 ccaaaaagag ctaaaacatc atcaggatgg gttaaggtaa tgtcaataga atactcttgc
    37021 aaatagagtc cctctttctt tcatctttat tgcttacatt ataacaaatt ttaaattctt
    37081 atgtgacgtt cacgtcagac ttttccttta tcacttttct ataaatcatc aaaaaagctg
    37141 ataagcctaa acttatcagc tttaactact ctaaggcatg ttaaataaga ttagcatctt
    37201 tgagcaattc ttcgataaag gtatccttga tttttttatg tccgattttc tcaatcagtg
    37261 caggaattgg caaatccata tccttgattg cctttttatc attaaggtaa taaaaggctt
    37321 tgagcaattc acgaatatca taggctgaat taaagacttc tgggatgcct cgttccacat
    37381 tcaagaagct atacactgct tccatggcag tacgaataga atactcagtc gtaaagaccg
    37441 tatctcgaga tggagattct gcaaagttcc caataaaggc caagttgact gaaccatctg
    37501 ggataacttt cggacggtct cctttgacgc gtggcataaa gtaactcgta atataaggca
    37561 tgtaaacagg aactgtattg atatagtcct gactcgctaa gtccttgatt ttatcaacag
    37621 gtaccccaag atgatacaac cattcttctg tgatttcttg acctgtacac tcctcaattt
    37681 tcttgtggac gtaatttccc tcaatattgg aataaagacc ataaatccag acagtggttt
    37741 cattatcttt ttgttcttta aaatgaggtt gacggtgaat ggcaaagctc atcatccagt
    37801 tggaatctgt aatagtgatg atgccgccag tgttcacttt gccatcgtgc aagtcacggt
    37861 gggtcaaacg ttcaatataa ggctcgatag ctgggtgttt tatggttgct gtggcagaca
    37921 caaaccagct ttcagcaggc aagtcctggt aaaacacttt aggataacca aaatcatctg
    37981 attgagcagc tagattttcc cataaattcc aagaaccacc taacgctttg gttggcttag
    38041 ccacttcgtg atgactaccg tatgtgctgc tttcagtaat agaaccattg gtcacaaaaa
    38101 ccaaatcatc aggtgttagc tcaatcgcct tagcctcccc agacaccgtc atatggatgg
    38161 tttttgctac ctttttacca gctgtttgct ccacctgaat atcggtgact ttagtatcaa
    38221 attggatgtc aacgtcgtgt gattctaggt aagcaataat cggtttgacc atagaatcat
    38281 attggttata tttgttgaac ttgagggagg taaaatctgg caaaccatca atatggtgga
    38341 taaacctcat cgcatagcgc cgcatttcta caacagagtg ccatttttca aaagcaaaca
    38401 tggttgccca atacacccaa aaattactct taaagaaatc ttctgagaag aactcttcaa
    38461 tggtttggtc tcctagagat tcttctgtct tcatgattaa atggattaat tcttttgact
    38521 gttttccgag cgtatactgg ccgtcatcat ccacacgatt tcctctcttg tgaatcaaac
    38581 gacagttgga tgagttagga tcatccttat ccaaccaata aaattcatct aaataagacg
    38641 caccgggaat ttccagtgag ggaatagacc gatacatgtc ccacatacac tcaaaatgat
    38701 tttccatctc acgaccacca cgggtcacaa aaccaagatg aggcttttca ataccatcta
    38761 aagaaccacc tgctaaaggc aattcctcaa acagatgaat gcgttcccca gccatatgcc
    38821 catcgcgaat aaggaaaaca gctgctgcta aaccagctaa accagtacca acaatataag
    38881 ccgatttctg atctacccct tcaggttttc gaggtgttgc aaaagcttcg taattaccac
    38941 tagtataata catttcaaga cctccttgaa tagtcaagca aagtgatatc atcactccaa
    39001 aggtaaggca gattgctcag ttgtcacgaa ataataggta ttcttctacc tttatcatga
    39061 tcatatcagg ttaattacct ttattttacc cctaaaccca tatttgcgct aataaaaacc
    39121 atctctttta gacataacgt taaaactgtc taaagggtga gaaaaacaac aggtattaaa
    39181 agcgtatctc agtctcttat agggcttact ctgtcagaat tgtcaaaaaa ctcacgccta
    39241 aacgtgagtt ttttttgata gcatgaatta agcattaaag gagacatgaa catgatcata
    39301 atggttttct gtaatactgc cgcgatctgg catggggttc catgtgtagg ctggtccgta
    39361 aatacttgca aatggcgcat agaatcgctg tttccaaata acgtatgaaa taccacgctc
    39421 tgccatatgg tcaatggcat attgagcaac ttgatcacca agagcagaat tttcaggcac
    39481 cataaaatca atggccaaac ctttaccatg atctcctgga tcacctggac ggtaaccact
    39541 aaatgacgta ataccaaagg cagaagccac ttcttctttg aaggctgctg tttgtggttg
    39601 aagtcctgca ttcattggat tgtaggcatg gtttggagcg taagaaaggc cgtttgaggt
    39661 tgcaacactt gtggtgtcag ctacagcttt ttgtgctgct ggcgcagagg ttttttcttt
    39721 ttctgctggg gctggggctt gtgctggggc cgcagaagaa acttcttctg aagcactctc
    39781 gttaggtaca ggcctattag ctgaagttgg atcttctgag atgtctgtct taggttcgac
    39841 ttcagtcgtt tcagctgctt taggagttgg aactgcttct tgtggtactt ctggctgctt
    39901 ttgtgattcg ctagacaact cagtcgaaac atcattcgtt gatgatgtga gctcagatga
    39961 cgctgtcaca aaactatctg gctttgcaga tgctaatggt gtcgttggga catcagatgg
    40021 tgtcgcagat ggtgccatag gaacagtcga ttgagaggtg gcagatgctt ggggtaatgg
    40081 ctcactgcta ggtacatgac taacgctagc tggactagaa gcaggcgctt gaaccgtcaa
    40141 agtcgttgcc tgaccgtgtt ggttgtagtt tgctgttagg atcgtgtctg gaaaaattaa
    40201 gtcaatatta gcaatatgat taatatctcc taagacatgc acatcaatcc ccattgcttc
    40261 agcaattgtg cttaaagtgt caccgtattt tacagtataa gtaaaaacat tatcaactag
    40321 gacgagttca gacttgattt ctgtaaccga tcgtggtgtc cactcttgtg cctgcgctgt
    40381 cgccaaaggt gctaacgaca aagcgacact tgtcacaaat aagctctttt tagtaataat
    40441 catctctgct tcctttttat ttttttctaa gctatatcat agcatatttt taagaaaaaa
    40501 agtagcttgt catttttttg aaagaaagtg atgtcatttt gtaataataa cgtgataacc
    40561 cttcaaaaga gtagatatga ctctttttta tccacgtatt aatgtgctag ataatcttcc
    40621 cagatttcat caaattgacc taaattaaag gaaaaactag cttgatcttc tagataccga
    40681 ctaatgagtt caaaatcatt ggtatgcttt ggaaaagtgg tgtcatcaaa caccaaatct
    40741 gctaaaatcg ccacaggttc atttgattta gggttacgtt gtgtcatcag ccagctgtaa
    40801 aatgattttc tcatgaccaa ttctcctcta aaaactgatg acgaatagca ctgctttgtg
    40861 cataccgctt gggattcttt ttataaaatc cttggtgata atcctctgcg agataaaatg
    40921 gctctgctgg ttcaatagtg gtgacaatgg gttggtcaaa acgtcctgaa gcttgcaagt
    40981 ttgcttttga ttgctctgca atttcttttt gtctttccgt tgtatagtaa atgacaggac
    41041 ggtagttgtc cccacgatct tcaaattgcc caaaggcgtc tgttggatcc gtctgcgccc
    41101 aatacaattc aactaattcc ttatagctga tctcttcagg gtcaaaaata atttcaacag
    41161 cttctgtatg tcctgttgtt ttggcacaaa cttgttcata gctaggattt gggagatgcc
    41221 cacctgtgta gccacttctg actgacaaaa tacctgcttg ctcctcaaaa ggttgcacca
    41281 tacaccagaa acaacctcct gcaaaaatgg ctctttccat tctctat
//
LOCUS       DAXMQE010000015        37575 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.015, whole genome shotgun sequence.
ACCESSION   DAXMQE010000015 DAXMQE010000000
VERSION     DAXMQE010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 37575)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37575)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37575
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.015"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            complement(<1..77)
                     /locus_tag="ACF4ZO_000913"
     CDS             complement(<1..77)
                     /locus_tag="ACF4ZO_000913"
                     /inference="COORDINATES: protein motif:HMM:NF019517.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gp58-like family protein"
                     /protein_id="HFD5486470.1"
                     /translation="MSRDPTLTLDESNLVIGKDGRVHYT"
     gene            complement(87..1094)
                     /locus_tag="ACF4ZO_000914"
     CDS             complement(87..1094)
                     /locus_tag="ACF4ZO_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronoglucosaminidase"
                     /protein_id="HFD5486471.1"
                     /translation="MTETIPLRVQFKRMTAEEWARSTVILLEGEIGLETDTGYAKFGD
                     GKNRFSKLKYLNKPDLDAFAQKKETDNKIAKLESIKADKDTVYLKAESKIELDKKLSL
                     AGGIVTGQLRLKPNSGIEKSSSTGGAINIDMSKSKGAAMVMYTNKDTTDGPLMILRSN
                     KDTFDQSVQFVDYRGKTNAVNIVMRQPPTPNFSSALNITSANEGGSAMQIRGVEKALG
                     TLKITHENPSVDKEYDKNAAALSIDIVKKKKGGGDGTAAQGIFINSSSGTTGKLLRIR
                     NKNEDKFYVNPDGGFHSYADSIVDGNLTVKNPTSGKHAATKDYVDKKFDELKKLIQKT
                     D"
     gene            complement(1091..3070)
                     /locus_tag="ACF4ZO_000915"
     CDS             complement(1091..3070)
                     /locus_tag="ACF4ZO_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFD5486472.1"
                     /translation="MITFLDHRDIEYGVISVIRHTNAVNGERSVSGEIYTNSDVLNNI
                     DRGWRLRFEDEYYVVIYAKPVDVGQKTQVSFDAIHQFFWDFSKSSIYEGLGDGSHTID
                     TYLETVFKGSGYRYKLEVGVNAFRKQSFNYKSRLDLFNEIIKATGLEFSVSGKVVRLL
                     KNIGTDLSTVVRKNFNMNDLTIEKNIDSFITYQKGFGAWTDPEDHSKGRLEAEYESPL
                     AKEYGRLEGAPLTDERFTVADNLKEALKSNVENSYKISVKIDMEDLTRAGYRCERPVA
                     GDYIMAINETLGFQERIRIVSFTSYYDATGALVKHEVTCNDIGSVKKQSVGSLSINSR
                     INQIDADIASAIEVATQALVSADGKNTVYGGTEMPKDEPKGTLKKGDILFLKAGDTTR
                     MYFWNGAEWEEPEVVNDPERWREDLEKQISEAIEKAKKAQEEINQRTDKELEEFRAAL
                     KNLALPEEAIKKITETIKVDDIPYIKQSFDDLKNKVSETSETSRLNAEILGNNGKTRY
                     NKNLLVGDPNRVKKIDEDYIEVEANDGGFKRGETYTISFSQTCELLKKVAVTLTQPHN
                     KGIKLVLTPTKAKMDAQTFEVTKDKQSIEVYPLSYTAVLTGDWYKSKQIDLNALEGRE
                     LALDMSYKDVVDGNNAAITGQWSDSPQIILDGGNQ"
     gene            complement(3080..3922)
                     /locus_tag="ACF4ZO_000916"
     CDS             complement(3080..3922)
                     /locus_tag="ACF4ZO_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail family protein"
                     /protein_id="HFD5486473.1"
                     /translation="MDLLIEKESQATRLSDFGIYNIAIEDSAPLLSVSHRAVKGRSGY
                     IYDGATFTTKTLKVKGRVTVSNVERLLDKQDELNALLVVDEPFYVTKMYPENSDLFNF
                     ELPGESTGDLQLIGSPHKPWKYRFKVILDDTIAYEFIGKTSQGLKYNLSFALRTAELP
                     FGETKPKDITLSGGSFAYAGTAKASQLEWPFIIELTPSGGQTNFYIEIDGRRFEFKQN
                     SQLQNSDKLLLTGIATTLNGNYVNAKTNYEYFIFNPNPNKRITYKTDFLGTIRILNFV
                     ELYK"
     gene            complement(3934..8316)
                     /locus_tag="ACF4ZO_000917"
     CDS             complement(3934..8316)
                     /locus_tag="ACF4ZO_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HFD5486474.1"
                     /translation="MPGTFDGSIFADVGANTKDYEQAMARIVSTTQNAFRKAQDTAVN
                     SSNKMVQIIGQIMAQLANNGESLGKRLGSAYATGLKLSIGEIQRIAASIGEKIPEPIK
                     NGFQKIIIPVASVIDKIRGNLTGFINQTKMQLQNLVGIGKIRSAFAKAATGVDILTQR
                     ASSKLNNLSAIFETVAGKLPRPFGTAFRKIASSVSTLNSSIQSVGGKISSSLGQQVLN
                     PALQSWNNFFSSVSAKASAFANKVSTSLFGRLTSSLANLSSKIGSSLSNGFSRMSSSA
                     ATSLNGISQKFANTSSAGERLKSTVMSIVQAFSLMAVAQKAMHAITGAIDGAVSRVDT
                     MNRFPKTMALFGYSAEQSKASIDKLSKGIEGLPTPLDSAVKSAQQLAITTGSLDKGTS
                     LALAFNNAMIGYGATTEGAEQALRQFSQSLGSGKIQAEEFNSVSEAAPGLISKMAEAF
                     GFGKNGVQDLKSALSDGKITAQEFADKMIELNDAQGGFAEMAQSSAGGIRTAWKNVHT
                     AVVKGVAGMISAFDEAAKANGMKTIAETLLSLKPAITSVFDTINSLIPNAVAAFARLK
                     QSINIDFSPLGASVKEVFALINIVFGDFAHTGELSEQAFDNLKAKITSLAPKVIALWA
                     VMNPASAISTIMPLLSLFGKVGLALGSLGTSVGAFGGIISSGIASASGVVGAFAATLS
                     GLPGVFATAAGRGLSVLGTMTSAMSSLVSLALAAIGPAAILGLVVAGLGLINSQFGAQ
                     IEQLLNTAVTKGPGIIQGLVKGITSKIPVLIASGTQLIAKFANAIAVLLPVIIQAGVQ
                     LITSLVQGIGQNATNLISSAIKIIGSFVSSIASALPQLISVGMELLLNVVNGIVQNIP
                     LIIQQAQQIIDSFGNSLQANLPSIISNGIAILVNLVQGITQMLPTVLQIATQVITSFV
                     SGIVQFLPQLLQGGIQIIISLVQGIIQNLPQIAQSAVQIIQSLASGLTQALPQIIAAG
                     IQLVAQLAVALIKGLPQIISAGIQLIMGLGKAMLGAIPNALSGVWEGIKSGFSSMWDQ
                     ITGKSSTSTAKVSADATVMAMNVGMQTTAIANQANTDTTSMLNSISQNTELANINATS
                     NATQMANNVNAQTGTMSLRGLNDSMSLASGISANMSVANINATTQAREMASGVNGATS
                     SMNLDAINHTLSLASGVGANMGAASTGATSQAQAMSSGVSNSLASMQSNSTKAASGLS
                     NSVTSEMSSAATSATSSVNRLSSAVESGFNKAKTSATTSMNGIANAVKTGFSSINSTA
                     KQSMANLVSSVTSGMSRATAVSNNACQKILSIFRALAGQMSSAGAYAGQGFANGLASS
                     AGTIYAIANSIAANVAATIRRALDIHSPSRVTKTLGAFTGEGFALGMAEWIGEINSLG
                     KAYATAVTDQNWGVNSTVSTSAKVNNSGINTSLDNLSEEVRQSQLSEPIFEVHNEIVG
                     DKIYTAVKEKESREQSKDSYFVFD"
     gene            complement(8331..8564)
                     /locus_tag="ACF4ZO_000918"
     CDS             complement(8331..8564)
                     /locus_tag="ACF4ZO_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486475.1"
                     /translation="MEGLEYKQLAERESLSELSLKLRYTLNAKKVDVGKLKYDKHRLT
                     IKRSYQKASRSQADSDSSIVERIQMLNNHFQNR"
     gene            complement(8639..9094)
                     /locus_tag="ACF4ZO_000919"
     CDS             complement(8639..9094)
                     /locus_tag="ACF4ZO_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail assembly chaperone"
                     /protein_id="HFD5486476.1"
                     /translation="MEFTAAKRNIDIKFDFKTMFKINNKLGTINPETGERNADGVGAL
                     FFNILERNESAIVDLVRLSAGSGKKALTEDEILDAIAESVDEEGTTEGLFAEIEKEMV
                     DSGFFRAKILKYIENMEKSARYLKAKDDMDATQIQIIEDVIGRMSNAVS"
     gene            complement(9148..9747)
                     /locus_tag="ACF4ZO_000920"
     CDS             complement(9148..9747)
                     /locus_tag="ACF4ZO_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage major tail protein, TP901-1 family"
                     /protein_id="HFD5486477.1"
                     /translation="MANTKKGTTIEITTGKPIVGKKIFYFIQSVDAPKKSQALLPAYR
                     TDGTTTMGGEYIDEQTQQGRVIEKATDEHSIDLTTYFVPTDPSVAVIEEAKKTGKSIK
                     IWEVIADESVKEQIQIPESTGPKKDVYPAKFGYAKIDEIERGTGISDLVEMSYTANIV
                     GALQDGKFPLTKEEIEMLENVYGYQNPGDTTGDYDNITK"
     gene            complement(9759..10118)
                     /locus_tag="ACF4ZO_000921"
     CDS             complement(9759..10118)
                     /locus_tag="ACF4ZO_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486478.1"
                     /translation="MDYSLETLYLKKVKNRLGVLDIPIYFKLPKSDVLEPFIVVGTNI
                     SDLSKTAQTGAVIDDFSLNIDAFLPGDSRLDAEEIKSRMLRLLGRNNQIKAQILVDNS
                     IGREVYRVAINITETLF"
     gene            complement(10122..10466)
                     /locus_tag="ACF4ZO_000922"
     CDS             complement(10122..10466)
                     /locus_tag="ACF4ZO_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97-gp10 family putative phage morphogenesis
                     protein"
                     /protein_id="HFD5486479.1"
                     /translation="MSLIYRMRGLDRFLRSVERKQKSVRIAVDKELSKSAARIERQAK
                     ILAPVDTGWLRAQIYSEQQRLLHYRLVSPALYSIYLELGTRKMEAQSFLDPALRKEWP
                     VLMANIKKMFKR"
     gene            complement(10463..10741)
                     /locus_tag="ACF4ZO_000923"
     CDS             complement(10463..10741)
                     /locus_tag="ACF4ZO_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486480.1"
                     /translation="MIYKDRVILVYVDEQDDFLDKRTVEKPSGKIPCMENTFTKSEQM
                     GLFGKYDLNAFKLHLQGHYDGFSKIIYKGKSRLIKGLAHHKNSTVIYV"
     gene            complement(10752..11108)
                     /locus_tag="ACF4ZO_000924"
     CDS             complement(10752..11108)
                     /locus_tag="ACF4ZO_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HFD5486481.1"
                     /translation="MGDKQLIDDIKLFIGISKGDGAQDELITLAIYESKERVLAKLNE
                     YSETEITKIPDRLRFIVRDVAIKRFNRINSEGAVEDSEEGKTFKWDSYLKEYESTLRS
                     AAIGKVYSGKGVARFI"
     gene            complement(11120..12007)
                     /locus_tag="ACF4ZO_000925"
     CDS             complement(11120..12007)
                     /locus_tag="ACF4ZO_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage capsid protein"
                     /protein_id="HFD5486482.1"
                     /translation="MAEKNLNTMADLGDIKSIDFVNKFSKNINDLLKLLGVTRRETLT
                     NDLKIQTYKWEVTLDQTDPGEGETIPLSKVTRTKDKDYTVKWFKKRRATTAEAIARHG
                     AARAITEADKRIMRELQNGIKDAFFTFLKTKPTKVKGVGLQKALSASWAKLATFNEFE
                     GSPLVSFVSPLDVANYLGDTKVGADASNVFGMTLLKNFLGMQNVIVMPSVPEGKIYST
                     AVENLVFASLNVKGGDLGGLFADFTDETGLIAAARNRQLSNLTYESVFFGANVLFAEI
                     PEGVVEATIEAAAVPGIGG"
     gene            complement(12020..12589)
                     /locus_tag="ACF4ZO_000926"
     CDS             complement(12020..12589)
                     /locus_tag="ACF4ZO_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HFD5486483.1"
                     /translation="MAEENVTTETTEQVDTQKEAVEYPKHEYERTFTRADISKMMAAE
                     RTKWESEQSAAIEKARTEGERLAKLSKDERAKEEEQKRLDAIAEREKAVAEREMRIET
                     HSLLVEKGLPLDFIDIVLATTAEEVKANIDNLQTIFDKAVEKRVNDRLTQKPPRTGNG
                     SVGMTKADIMAIEDDDERMRLIAENRNLF"
     gene            complement(12757..13023)
                     /locus_tag="ACF4ZO_000927"
     CDS             complement(12757..13023)
                     /locus_tag="ACF4ZO_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486484.1"
                     /translation="MNKRIKKKRKLETAVVMLVAENAMQAEAIKNQNKQIMELKSIVQ
                     RNALATNEELAAVKAATLDNQSVIKAIGDTVDYIKKNYKRKWGK"
     gene            complement(13028..13216)
                     /locus_tag="ACF4ZO_000928"
     CDS             complement(13028..13216)
                     /locus_tag="ACF4ZO_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486485.1"
                     /translation="MGVRPSSFFISIIHHPIKTIKEENMFIWQMVLVALGVLVLILIV
                     GIAAIAVKSIIAELKKEG"
     gene            complement(13244..14692)
                     /locus_tag="ACF4ZO_000929"
     CDS             complement(13244..14692)
                     /locus_tag="ACF4ZO_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HFD5486486.1"
                     /translation="MLVVKKNQRQKSLNYWQKRQEDILSYLDRTDLDVFSELQKLYNE
                     QAFELQKELFDFYTKYSEENKMTYQDVVKKLRHEDLSDYVANANKYRKQAEKDPELLK
                     RLNEQYVSARATRMDALNLELVYRAGILKGVLDSAFENHLKKVASYAYKKAMGGRSGT
                     INGPVLEELVRTPFDGYNYSEQLWGNTDNLVKNLQKRLKQGFVRGEHPRAMARDLAKR
                     FNVANHRAETLIRTDGTMVINNATARRYLNAGLKYYRDLVRLDDRTTEICRTIAKENK
                     RKLLSELKPGINVAPYHFNCRTTIIPDEDELSIEVEPIDDKSTKYFKDVTSDWIDGNE
                     HKPQLSLLNEYVKNGTPYKVDGHSVVLDHSNYEYRVANWLSKKTGLQVDMVPRVNSPE
                     HIKTPDYLVDVAPFDLKEITGSGKNVIDGNLRKAKKQATNIIFDITKTPLSFEEIMGQ
                     LEHIYMIDRRGLDISIIKNKDEVLAVLEKEGG"
     gene            complement(14652..16184)
                     /locus_tag="ACF4ZO_000930"
     CDS             complement(14652..16184)
                     /locus_tag="ACF4ZO_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0046798 - viral portal complex [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0051027 - DNA transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HFD5486487.1"
                     /translation="MEEKQFLAGTRFNENANKQFIMLQEDFEAIDYESKLWIDQLKNY
                     ISRFKAEQLERLKELKRYYLGDNNIKYRPAKTDKYAADNRIASDFAKYITVFEQGYML
                     GVPVEYKNENKDLQAAIDLMSVRNNEDYHNVKIKTDLSIYGRAYELLTVEKIDDKKTE
                     VKLYQLPAEQTFVIYDDTYQRNSLMAVHFYDIDYGSGKRKQIIKAYTSDTIYTYEDYN
                     LETKGMRLKDYEGHFFKGVPVNEYANNEERTGAYESVLDNIDAYDLSQSELANFQQDS
                     VNALLVIAGNAYTGADENDYLDDGRLNPNGRLAISIGFKKAQVLILDDNPNPNGVKPQ
                     AYFLKKEYDTAGSEAYKNRLVADILRFTFTPDTQDMKFSGVQSGESMKYKLMASDNYR
                     EKQERLFKKGLMRRLRLAANIWAIKGNEATTYSLVNDTSIVFTPNLPQNDNEIVTAAQ
                     NLYGIVSDQTIFEILNTVTGVDAEAELKRLKEEADKKQSLPEPRLVGDASGQEEPTAE
                     KP"
     gene            complement(16200..17477)
                     /locus_tag="ACF4ZO_000931"
     CDS             complement(16200..17477)
                     /locus_tag="ACF4ZO_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HFD5486488.1"
                     /translation="MTTKQRPKINIVIKHPSKVFNKHIYDKLYNYSNFTEVHYGGASS
                     GKSHGVFQKIILKALNPKFKHPRKILVLRKVGATVRDSVFADIMSNLSYFGILDKCKI
                     NMSAFRITLPNGAEFIFKGMDNPEKIKSIKGISDVVMEEASEFTLDDYTQLTLRLRDK
                     KHLEKQIYLMFNPVSKVNWVYKAFFVKTPKNTVVYQTTYKDNRFLDDVTRENIEELAN
                     RNEAYYKIYALGQFATLDKLIFPKYDKQILNKDKLSHLPSFFGLDYGFINDPSALLHV
                     KIDDANKKLYILEEYVRKNLTNDKIANAIKDLGYAKEEIRGDSAEKKSNQELRNLGIP
                     RMIDVTKGPGTVMQGIQYLLQYDWIVDERCVKTIEELENYTWKKDKKTNEYTNEPVDS
                     YNHCIDAIRYAVQDRIYQSADRSKRMKNAKYYF"
     gene            complement(17467..17919)
                     /locus_tag="ACF4ZO_000932"
     CDS             complement(17467..17919)
                     /locus_tag="ACF4ZO_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HFD5486489.1"
                     /translation="MLGGDGKLSKLTLKQKRFADEYIISANATAAAIKAGYSKKTARS
                     IGQENLTKPDIKAYIDERLEKLESEKIATQEEVLQYLTSIMRGDQQEKTLISVGEFGQ
                     KIVDIDVGAKDRIKAAELLGKRYRLFTDKVEMDVSSDVTINVGEWDDD"
     gene            complement(18009..18425)
                     /locus_tag="ACF4ZO_000933"
     CDS             complement(18009..18425)
                     /locus_tag="ACF4ZO_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HFD5486490.1"
                     /translation="MSRLSNAQLKAFDEWLFDYRFIDNKIALRKLELQTDMNTAVDKN
                     IGGGRANFVSKVTEDVVARWDSDRELKGLSNFKEAVIATLNLLDEELTDIFNLRWGVG
                     SSNTWEEIAYTRHLSRKSIYRKRERILEIFSKKIGM"
     gene            complement(18558..18830)
                     /locus_tag="ACF4ZO_000934"
     CDS             complement(18558..18830)
                     /locus_tag="ACF4ZO_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486491.1"
                     /translation="MTEEQMIDCLLYELVKKDKAIKKKNIIITALTVMLLIVVSGLGI
                     SLKSYYEPQIYGLRAQLSRTQKQLKRASDDRARQTKRIAELTKNGG"
     gene            complement(18823..18993)
                     /locus_tag="ACF4ZO_000935"
     CDS             complement(18823..18993)
                     /locus_tag="ACF4ZO_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486492.1"
                     /translation="MKKEYVVRIYTGREKNFEAKPQFEEKTFTRKADMLKFWNSCEAT
                     VKEKYTREREND"
     gene            complement(18994..20316)
                     /locus_tag="ACF4ZO_000936"
     CDS             complement(18994..20316)
                     /locus_tag="ACF4ZO_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0140658 - ATP-dependent chromatin
                     remodeler activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SNF2-related protein"
                     /protein_id="HFD5486493.1"
                     /translation="MRLHEYQEYAKTWIVEHPYCGLLLDMGLGKTLTTLSAIDEIQNI
                     FSEDHKILIVAPKKVAEETWPTEIGKWHFDFTYSKVLGSEGKRIEALETEADIYLINR
                     ENVTWLVEYYKTKWPFTFVVIDELSSFKSSKSKRFRALRKVRPKVQRLVGLTGTPAPN
                     SLIDLWPQIYLMDRGARLETSQTRFKDKYFVPDKRNGLIIYSWALRDGAEAEIYNKIE
                     DICVSMKAKDYLKLPPRTNNVVSVKLSNMKAYKQLEADLVLEFKNKEISAANSAVLAN
                     KLLQMANGAIYDDDKATVAIHDDKLDALENVVEESQGQPILVFYQYQHDLERLKKRFP
                     QAEELTSVDKWNSGKIPILLCHPQSAGHGLNLQKGGHIIVWFGLTWSLEYYQQANARL
                     DRQGQTEPVIVHHIVAENTVDEKVLRILQGKEKNQNALLEAVKAQLGV"
     gene            complement(20313..20588)
                     /locus_tag="ACF4ZO_000937"
     CDS             complement(20313..20588)
                     /locus_tag="ACF4ZO_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VRR-NUC domain-containing protein"
                     /protein_id="HFD5486494.1"
                     /translation="MRTEKDIENYLKKKTKGLCLKFASPGTIGVPDRIVVMNTGTFFV
                     EVKAPGKKPRPSQVAMHKKIKKAGQHVWVVDSYESVDIALKEMENWV"
     gene            complement(20954..23338)
                     /locus_tag="ACF4ZO_000938"
     CDS             complement(20954..23338)
                     /locus_tag="ACF4ZO_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003896 - DNA primase activity [Evidence
                     IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage/plasmid primase, P4 family"
                     /protein_id="HFD5486495.1"
                     /translation="MKQEKLIVKSSPLQELHIATGSSRTAKTWKNITLTWQELVERLE
                     KPTVTQETFAEYQKMSRAEKGQAKDVGGFVGGWLKQGKRKNENVQSRSLVALDADSPS
                     KDFLDRLDLLADYAYVLYSTHSHSKKAAKYRLIIPTDRLMMPDEYEPVARYLANQLGM
                     SNFDDTTYQSVRLMFWPSHSRDAEFTFKYNDEAFLSVDEVLDTYPDWHDSSFWPESPT
                     HAVKRQREAKKQGDPLSKKGLIGAFCRNYDIRQAIATFLPEVYEEGATPDRYTYTEGS
                     TANGLVIYDDVFAYSHHGTDPVGDTLVNAYDLVRIHKFGEQDSEAKDNTPTNKLPSSK
                     AMNAFVSDLPEIKDYLMAEALGDFDEELPVEDDRSWLEIDERGEPEVNSYLLATQIIK
                     EVPIYWDGLEFLRYDAKKGIWLPNAEEYLKSYISTKKLGKITKIRHISETIVAIKAQA
                     FSSEVFTESDLNKIVLANGVYDLRDNSFKTKFDPEVHARSSHPVVYDPEATCETFEGF
                     LRETVGAENIDFIFEWFGYNFYREYTIQKMLFIYGSGGTGKSTLINILREMIGADNYS
                     AVTLQYLMQERFAKIGLYRKTANFDTDAKPQYLADGATLKMLTGEDTIHADRKNKEPI
                     NFYNYAKLSFAMNELPPMRDFSGGLKRRMMILEMDKVLTQEVKAKYPLDKIMSEVPGI
                     FNRAMEGLRKALSKRDFSISASMRSSVEKWEKGNDVVAMFLEDECDLSEDFKVPVRDV
                     YPAYKFYCQDSGYKPLARNSFTQRMNELNFENKNAKMGGKTVRCWIGFRIKGEF"
     gene            complement(23343..25265)
                     /locus_tag="ACF4ZO_000939"
     CDS             complement(23343..25265)
                     /locus_tag="ACF4ZO_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase"
                     /protein_id="HFD5486496.1"
                     /translation="MRHLNIDIETYSSNDIKNGVYKYADAEDFEILLFAYSIDGGEVE
                     CLDLTRQSLPEDIKDMLFDDKVRKHAFNAQFERVCLSRYLGLPYYLDPCQWQCTMVLA
                     QELGLPSSLEKCALYLKLAQEKDTSGKNLIRYFSLPCKPSKTNGGRTRNLPEHAPEKW
                     QMFIDYCIQDVVVEMAIAEKLESVPVHDREWDYYACDQRINDRGVALDKELVASALYC
                     KDVKMESLSGELKALTGLDNPNSRTQLLPWLKEHGYSASGLTKADVEKELKTAEGELK
                     RVLELKLQTAMSSLKKYEAMERARCSDGRVHGLLQFYGASRTGRWAGRVVQVQNLARN
                     YIKDLDDAREYVKKRDIDAVEILYDSLNDTLKQLVRTALVAKDGCTFYVSDFSAIEAR
                     VIAWFAGEQWRLDVFSTHGKIYEASASQMFGIPIEEIDKELRQKGKISELALGYQGGP
                     GALKQMGALNMGVKEEELQGLVDDWRRANKKIVQFWKDVQRAAIKAIKSRAPVRLGKL
                     RFRYRKGFLFITLPSGRNLAYARAKVEPGDYGDKIVYEGQGDKAYFTAQETYGGKLVE
                     NIVQATARDILAEALLRIEAAGHGVVFHVHDEAIIEGSGLTIEEVNDLMAQAPEWAEG
                     LPLNSEGYITKYYMKD"
     gene            complement(25308..25871)
                     /locus_tag="ACF4ZO_000940"
     CDS             complement(25308..25871)
                     /locus_tag="ACF4ZO_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2815 family protein"
                     /protein_id="HFD5486497.1"
                     /translation="MTTTPNTTKVVTGKVRLSYVALLEPKAFEGQEAKYSTVILIPKT
                     DKVTIKKIKDAQKAAYEAAKDNKLKGVKWERVKTTLRDGDEEMDTEEHPEYTGHMFMS
                     VSSKTKPQIIDKYKNFVDSAEEVYSGVYARVSLNAYAYNTAGNKGISCGLNNVQIVAK
                     GDYLGGRSSADADFDEWNEEEDEDDIL"
     gene            complement(25885..27042)
                     /locus_tag="ACF4ZO_000941"
     CDS             complement(25885..27042)
                     /locus_tag="ACF4ZO_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015986706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2800 domain-containing protein"
                     /protein_id="HFD5486498.1"
                     /translation="MPVENHALLSASSAHRWLYCPMLPRLEADYPSRDTVYTQEGTSA
                     HELSEIKLMYKSGKITKRKFNTLTKAFKENSDFYNEEMEEMTELYTDIVMEHLNTYEN
                     AEIELEKRVDFSDWVPGGFGTSDVVILADGVIEIIDLKYGKGMPVSANQNPQMGLYAL
                     GAYASYDMVYDFDRIKMTIIQPRLDSVSSVDIYVEELLYWADNVVLPMAAQADAGIGD
                     WNLSEKVLQWSPVAAKLVPRAQENWELIDKYDYQEPVYLSDEAVAEILDKASAIKKWV
                     ESVEAYALKEALSGKEVPGYKIVEGRSNRVITDKDKAIDILQDNGFDDEIFKPKELLA
                     MGALEKLIGKTTFADLLAEVIDKPQGKPVLVPEKDKRPAINSLEQAIKDFE"
     gene            complement(27042..27341)
                     /locus_tag="ACF4ZO_000942"
     CDS             complement(27042..27341)
                     /locus_tag="ACF4ZO_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486499.1"
                     /translation="MIEVTFKAESMAGVFDAMREALDMPKTVTKDVVEEKPAPKKKEE
                     SVTLTLADIKKMAKAKVEEGKSKDIKEVLREMNVAKVGELEEYQFAEFVEKLEAL"
     gene            complement(27429..27632)
                     /locus_tag="ACF4ZO_000943"
     CDS             complement(27429..27632)
                     /locus_tag="ACF4ZO_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486500.1"
                     /translation="MNYLEYALAYLERELEIIDDEVIEVELPGGDWEFVPNPYYEEGL
                     HDSPYYRSQVAKDILDIKGLLGR"
     gene            complement(27777..28160)
                     /locus_tag="ACF4ZO_000944"
     CDS             complement(27777..28160)
                     /locus_tag="ACF4ZO_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486501.1"
                     /translation="MTTFEKVISKLNRIEGELAKPESERRDSLPILSAQLSAIKQDLK
                     LMLWVELPSLNNVEKYEALYQGNDFKFSETFLERQATRKAFWRRLAKETFKEDQDRRN
                     FVKLAEKEFKGATLSWQEFLWGKKK"
     gene            complement(28157..28364)
                     /locus_tag="ACF4ZO_000945"
                     /pseudo
     CDS             complement(28157..28364)
                     /locus_tag="ACF4ZO_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647288.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(28357..28527)
                     /locus_tag="ACF4ZO_000946"
     CDS             complement(28357..28527)
                     /locus_tag="ACF4ZO_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015986705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486502.1"
                     /translation="MNKLELFLLAITIILAIIARVQYEVIKKHNSPENKRRIFREVAL
                     ENSKKWSAERYV"
     gene            complement(28556..28813)
                     /locus_tag="ACF4ZO_000947"
     CDS             complement(28556..28813)
                     /locus_tag="ACF4ZO_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486503.1"
                     /translation="MQSQLTYDLLKKQIAEELFDEFKKLIQEKDLANQWVNQTTLVTE
                     YGYSRQTVKRMESYGLKSFKNGKDRMYCLADVNEIKHLMKQ"
     gene            complement(28901..29101)
                     /locus_tag="ACF4ZO_000948"
     CDS             complement(28901..29101)
                     /locus_tag="ACF4ZO_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486504.1"
                     /translation="MTDAEKQNYDALFINIFERLEKLEEGYDFSSVVTTTEVQNSGGV
                     QYCECEEDGTVVKTVSKRSLGN"
     gene            complement(29152..29343)
                     /locus_tag="ACF4ZO_000949"
     CDS             complement(29152..29343)
                     /locus_tag="ACF4ZO_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486505.1"
                     /translation="MSDNTVAVEKIKKYLLDNKLKQVDLAVTYNKEPQDVANILAGRK
                     KDPASNRFVLKVISDLKIR"
     gene            29982..30332
                     /locus_tag="ACF4ZO_000950"
     CDS             29982..30332
                     /locus_tag="ACF4ZO_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFD5486506.1"
                     /translation="MFSTFEKIKELAKKQGKSLGQVEEDLNYGRNTLYKIKNSTPNAE
                     RLGEIANYFNVSTDYLLGRTDNPKIAQDGHTSVAIDLKKDAEETFFFDGHELNDEDID
                     LITSILETRIKNRK"
     gene            30346..30729
                     /locus_tag="ACF4ZO_000951"
     CDS             30346..30729
                     /locus_tag="ACF4ZO_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HFD5486507.1"
                     /translation="MMTPETVCQEKGIDLVYFDGRGTNTPGMFNKKHNVIAIDTYLDG
                     IYKHKVIYHELGHREHTASYYKLNKEKAELQADRCMIHHLLKEELSHWDNMEDFNYIQ
                     FMEKYELTSIADEVMVKEELEFLIS"
     gene            30740..31291
                     /locus_tag="ACF4ZO_000952"
     CDS             30740..31291
                     /locus_tag="ACF4ZO_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015986700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486508.1"
                     /translation="MDIAKLKGFAIAAAGKAKEGAIKANELRKKASQESKIILPPALN
                     LGLGTPTTIRKTIDGKYYIGFYSETPELYEFVNLQFDGSRIIEKTVTKGKTTQKGRSG
                     SVLGGAAIGTVLAPGVGTIIGGIAGGARKKKGTINTTATTTSEEIPGKATVALRNIQT
                     GEIKTLKTKLMQAQYVSVNNFFK"
     gene            31467..32555
                     /locus_tag="ACF4ZO_000953"
     CDS             31467..32555
                     /locus_tag="ACF4ZO_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFD5486509.1"
                     /translation="MIEKYTKKDGTTAYRLRAYLGVDPMTGKQVRTTRQGFKTEREAK
                     RTEVKLVDDFQRQGAWKNNDKTTFDDAARLWFEQYKNTVKPSTFLVNQNYYKSTIKPH
                     IGKSQISKITVMACQNLINHLAQYSACASYISVINRIFKFAVHLGIIENNPMDRTIRA
                     RCTYAHKEKMFYSKEELLIFLDIVKKEESLEMLLIYRLLAYGGLRIGEAVALYDTDFD
                     FTNNTISITKTLAQTKAGKVIQNPKTKKSSRTISMDQETMRLAKEYMRQSVRPLHGSF
                     RVFNLLTSTVRRRLKRTVERHHLKKINPHGFRHTHASLLFEAGVPAKLAQERLGHAKI
                     SITMDLYTHLSKNQTDNVAEKLADFIAI"
     gene            complement(32687..33442)
                     /gene="recO"
                     /locus_tag="ACF4ZO_000954"
     CDS             complement(32687..33442)
                     /gene="recO"
                     /locus_tag="ACF4ZO_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HFD5486510.1"
                     /translation="MQLTESLGIVLFNRNYREDDKLVKIFTEVAGKQMFFVKHISRSK
                     MSSIIQPLTIADFIFKLNDTGLSYVVDYSNVNTYRYINNDIFRLAYASYVLALADAAI
                     ADNESDSHLFTFLKKTLDLMEEGLDYEILTNIFEIQILDRFGISLNFHECAICHRTDL
                     PLDFSHRFSAVLCSEHYYKDNRRNHLDPNVIYLLSRFQKITFDDLRTISLNKDIKKKL
                     RQFIDELYHDYVGIKLKSKTFIDNLVKWGDIMK"
     gene            complement(33628..34590)
                     /locus_tag="ACF4ZO_000955"
     CDS             complement(33628..34590)
                     /locus_tag="ACF4ZO_000955"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004749 - ribose phosphate diphosphokinase
                     activity [Evidence IEA];
                     GO_process: GO:0009156 - ribonucleoside monophosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HFD5486511.1"
                     /translation="MSYSDLKLFALSSNKELAEKVASAMGIQLGKSTVRQFSDGEIQV
                     NIEESIRGHHVFILQSTSSPVNDNLMEILIMVDALKRASAEKISVVMPYYGYARQDRK
                     ARSREPITSKLVANMLEVAGVDRLLTVDLHAAQIQGFFDIPVDHLMGAPLIADYFDRH
                     GLVGEDVVVVSPDHGGVTRARKLAQFLQTPIAIIDKRRSVDKMNTSEVMNIIGNVSGK
                     KCILIDDMIDTAGTICHAADALAEAGATAVYASCTHPVLSGPALDNIQRSAIEKLIVL
                     DTIYLPKERLIDKIEQISIADLVAEAIIRIHEKRPLSPLFEMGN"
     gene            complement(34843..36039)
                     /gene="pcsB"
                     /locus_tag="ACF4ZO_000956"
     CDS             complement(34843..36039)
                     /gene="pcsB"
                     /locus_tag="ACF4ZO_000956"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002996017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan hydrolase PcsB"
                     /protein_id="HFD5486512.1"
                     /translation="MKKRILSAVLVSGVTLGAATTVGAEDLSTKIAKQDSIISNLTTE
                     QKAAQNQVSALQAQVSSLQSEQDKLTARNTELEALSKRFEQEIKALTSQIVARNEKLK
                     NQARSAYKNNETSGYINALLNSKSISDVVNRLVAINRAVSANAKLLEQQKADKVSLEE
                     KQAANQTAINTIAANMAMAEENQNTLRTQQANLEAATANLALQLASATEDKANLVAQK
                     EAAEKAAAEALAQEQAAKVKAQEQAAQQAASVEAAKSAITPAPQATPAAQSSNAIEPA
                     ALTAPAAPSARPQTSYDSSNTYPVGQCTWGAKSLAPWAGNNWGNGGQWAYSAQAAGYR
                     TGSTPMVGAIAVWNDGGYGHVAVVVEVQSASSIRVMESNYSGRQYIADHRGWFNPTGV
                     TFIYPH"
     gene            complement(37404..37491)
                     /locus_tag="ACF4ZO_000957"
     tRNA            complement(37404..37491)
                     /locus_tag="ACF4ZO_000957"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(37455..37457),aa:Ser,seq:gct)
     gene            complement(37501..37574)
                     /locus_tag="ACF4ZO_000958"
     tRNA            complement(37501..37574)
                     /locus_tag="ACF4ZO_000958"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(37538..37540),aa:Ile,seq:gat)
BASE COUNT        10632 a         8215 c         6482 g        12246 t
ORIGIN      
        1 aatgtgtaat gcacacgtcc gtccttacca ataacgagat ttgactcgtc taatgttagt
       61 gttggatctc tactcattta tcctccttaa tctgtttttt gtatgagttt ttttaactca
      121 tcaaattttt tatctacgta atctttagtc gcagcatgtt ttccagatgt tggattttta
      181 actgttagat taccatccac gattgaatct gcatatgagt gaaagccacc atctggattt
      241 acataaaatt tgtcttcatt tttatttcta atcctaagca gcttccctgt cgtgcctgag
      301 gatgaattga tgaaaatgcc ttgtgcagca gtaccatctc caccgccttt ctttttttta
      361 acgatatcaa tagataacgc tgcagcgttt ttatcgtatt ctttgtcaac gcttgggttt
      421 tcgtgtgtga ttttgagcgt tcccaatgct ttttcgacgc ctctaatttg catcgcacta
      481 ccgccttcgt tagcactggt tatattaagt gccgaggaaa aattgggggt gggtggctga
      541 cgcattacaa tatttacagc attagtctta cctctgtagt ccacaaattg aactgactga
      601 tcaaacgtat ctttgttaga acgtaaaatc atcaatggtc catcagtagt atctttattt
      661 gtatacatca ccatagcagc acctttcgat ttagacatat caatgttaat cgctcctcct
      721 gtagaagatg acttctcaat accactatta ggtttaagcc gtagttgtcc tgtcactatg
      781 ccacctgcca aactcaattt tttgtctagc tctattttgg actctgcttt taagtaaaca
      841 gtgtctttgt ctgctttaat tgattctaat ttggcgattt tattatcagt ttcttttttt
      901 tgtgcaaacg catctagatc tggtttatta aggtacttaa gcttactaaa tcggttttta
      961 ccatcaccaa acttcgcata tcctgtgtcg gtctcaagac ctatctcacc ctcaagtaag
     1021 atgacagtac tgcgagccca ttcttcggca gtcatccgct taaattggac tcgcagcggt
     1081 atagtttctg tcattgatta cctccatcta aaattatttg tgggctgtct gaccactgcc
     1141 ctgttatcgc ggcattattg ccatccacaa catctttata gctcatgtcc agagctaatt
     1201 cccgcccctc caacgcattt aaatctattt gcttagattt ataccaatcg ccagttaaaa
     1261 cagccgtgta gcttaaagga tagacctcta tagactgttt atccttagtg acctcaaacg
     1321 tctgcgcatc catttttgcc ttagttggtg tcagcaccag cttgatacct ttgttatgcg
     1381 gctgtgtcag cgtgacagcc acttttttga gtagctcaca agtctggcta aagctaatcg
     1441 tgtaggtctc gccacgctta aaaccaccgt cgttggcttc tacctcgatg taatcctcat
     1501 caattttttt aacacgatta ggatcgccaa ccaagaggtt tttgttgtag cgggtcttac
     1561 cgttattccc taaaatttcg gcgtttagac gggatgtctc gctcgtttca ctgaccttgt
     1621 ttttgaggtc atcaaagctt tgtttaatat acgggatgtc atcaactttg atagtctctg
     1681 tgattttttt aatcgcttcc tctggtaacg ctaggttttt gagggcggct ctaaattctt
     1741 caagctcttt atcggtgcgt tggttgattt cttcctgtgc ttttttggct ttttcgatcg
     1801 cctcagagat ttgtttttcg aggtcttcac gccatcgttc tgggtcgttc acaacctcag
     1861 gttcttccca ctcagcacca ttccagaaat acattctagt agtatcgcca gcttttagga
     1921 ataatatgtc tccttttttt aaggttcctt ttggttcatc tttgggcatt tctgtgccac
     1981 cgtaaacagt atttttcccg tcagcagata ctagtgcttg tgttgctact tcaattgcag
     2041 aagcaatatc tgcatctatc tgattgattc tactgtttat agacagactt cctacgcttt
     2101 gttttttcac agatccgata tcattacaag tgacttcatg ttttactaaa gctccagttg
     2161 cgtcgtagta gcttgtaaaa gaaactatcc gtatacgctc ttgaaaacct aaagtctcat
     2221 ttatcgccat aatgtagtca ccagcaaccg gcctctcaca tctataccca gctctcgtta
     2281 aatcttccat atcaattttt actgatatct tatatgaatt ttcaacatta ctttttaaag
     2341 cttcttttag attatctgcc accgtgaagc gctcatccgt cagaggcgcc ccttcaagtc
     2401 gaccgtactc cttggcaaga ggactttcgt attccgcctc aagtctcccc ttagagtggt
     2461 cctctgggtc ggtccatgca ccaaagcctt tctgataggt aataaagcta tcaatatttt
     2521 tttcaatggt aaggtcattc atgttgaaat tttttcgtac cactgttgac agatcagtac
     2581 ctatgttttt taatagccga acaactttcc cgctgactga aaattcaagt ccggtcgctt
     2641 taataatctc attgaataaa tctaacctgg acttataatt aaaagattgt tttctaaatg
     2701 cgttcacacc tacttctagc ttatagcggt acccactacc tttaaatact gtctctagat
     2761 aggtatcaat ggtatgagac ccatctccga gaccctcata gatactactc ttgctgaagt
     2821 cccaaaaaaa ttggtgtatg gcatcaaacg aaacttgcgt tttttgacca acatcaacag
     2881 gctttgcgta aataacaacg taatactcat cttcaaatct aagtcgccac cctctatcga
     2941 tattattgag gacatcactg tttgtataaa tttccccgct cactgagcgc tcaccattaa
     3001 cagcattagt atgcctaatg acactaatga ccccatactc aatgtcacga tgatccaaaa
     3061 aagtaatcat tagacctccc tatttataca actctacaaa atttaaaatc ctaatcgtgc
     3121 caagaaaatc cgttttgtaa gtaattctct tgttaggatt aggattgaag ataaaatact
     3181 catagttcgt tttagcattg acataatttc cgtttagtgt ggtagctatg cctgtcaaaa
     3241 gtaatttatc actattttgt agctggctat tctgcttaaa ctcaaagcgc ctgccatcaa
     3301 tttcaatata aaaattagtc tgacctccag aaggagtaag ctctataata aaaggccact
     3361 ctagctgact tgctttagcg gttcctgcat aggcaaaact gccccctgat agagttatgt
     3421 cctttggctt tgtctcaccg aaaggtaatt cagcagttct tagcgcgaag gaaagattat
     3481 attttagtcc ttgactggtt tttcctataa attcataagc aatagtgtcg tctaagatga
     3541 ctttaaatct atatttccaa ggtttatgag gagagccaat aagttgcagg tctcctgtgc
     3601 tttcccctgg aagctcaaag ttaaatagat ctgagttttc agggtacatc ttagtcacgt
     3661 agaaaggttc gtcaacaaca agcagagcgt ttagttcgtc ctgtttgtcc aaaagtcttt
     3721 ctacgttgct taccgtcact cttcctttga ccttaagcgt tttagtcgta aaagtagccc
     3781 catcgtagat gtaaccactc cttcctttga ctgctcggtg tgatacagat agtaaaggag
     3841 cgctatcttc aatagcaata ttataaatac caaagtcaga caacctagtt gcctgactct
     3901 ctttttctat taataaatcc aaaatactcc cttctagtca aaaacaaaat aagaatcttt
     3961 agattgctct cttgattctt tttctttaac agccgtgtaa attttatctc caacaatctc
     4021 attatgcact tcaaagatag gctctgacaa ttgagactgc ctaacctctt cgctaagatt
     4081 atcaagagag gtattgattc cactattatt aactttagca gatgttgaaa cagtactatt
     4141 taccccccag ttttgatcag taactgctgt tgcgtatgct ttacctaggc tattgatctc
     4201 acctatccac tctgccatac cgagggcaaa cccctctcca gtaaatgcac ctagtgtttt
     4261 agtgacacga gatggtgagt gaatatctaa agcgcgtcta attgttgctg ctacattagc
     4321 ggcaatgctg ttagctattg cgtagattgt gcctgcgcta ctagctagac cattagcaaa
     4381 accttgacct gcataagctc ctgcagaaga catctgccct gccaaagccc tgaatattga
     4441 gaggatcttc tgacaagcat tattagacac cgcggttgca cgagacatcc cagaagtcac
     4501 tgaacttaca aggtttgcca tagattgctt tgcagtactg ttaatgctac taaatcctgt
     4561 tttaaccgca ttggctatcc cattcattga ggttgttgct gaagtcttcg ccttattgaa
     4621 gccagactcg accgccgagg acaacctatt aacgcttgag gttgcagagg ttgctgcaga
     4681 agacatttcg cttgtcacac tattagacag accagaggct gctttagttg agtttgactg
     4741 cattgatgcc aggctgttac tcacccctga gctcatagct tgcgcctgag aagttgcacc
     4801 tgtgctagca gctcccatgt tcgcaccaac accactagct aagctgagcg tatgattaat
     4861 ggcgtctaga ttcattgaag aagtcgcacc attaacccct gaagccattt ctcgagcctg
     4921 agtagtagcg tttatattag cgacagacat attagcgcta atgccactcg caagagacat
     4981 cgaatcattc aacccccgaa gactcatcgt tcctgtctga gcattaacgt tattagccat
     5041 ctgtgtggca tttgatgtag cgtttatatt agcaagctct gtattttgac taatgctatt
     5101 aagcatagat gtcgtatctg tattagcttg attagctata gctgtcgttt gcatcccaac
     5161 attcatggcc atgaccgtgg cgtccgcaga gactttagct gtacttgtgg aactcttacc
     5221 tgtgatttgg tcccacatcg aactgaatcc gctcttaata ccttcccaaa ctcctgaaag
     5281 agcgtttggg atagccccta acatggcttt accgagcccc ataattaatt gaatacccgc
     5341 agaaataatc tgtggaagcc cctttatcaa ggctacggct agttgcgcaa caagctgaat
     5401 gcctgctgcg ataatctgag gtagagcttg cgtcagtcca gaagctaaag actgtataat
     5461 ctgtacagca gattgtgcaa tctggggtag attttgaata atcccctgca caaggctaat
     5521 aatgatttga atgccacctt gaagtaactg cggtaaaaac tgtacaattc cagatacaaa
     5581 actcgtaatg acttgagtag ctatctgcag aacagttggc aacatttgag taattccctg
     5641 tacaagattc accaaaatag ctataccgtt gctaataata ctaggaaggt tagcctgtaa
     5701 actattccca aaactatcaa taatttgctg ggcttgctgg ataataagag gtatattttg
     5761 aactatgccg ttgacaacat ttaataatag ctccattcca acagaaataa gctgcggcaa
     5821 tgcactcgca attgaactaa caaaactacc aatgattttt attgctgaac taattaaatt
     5881 cgttgcattt tgtccaatac cttggacgag actcgtaatt agctgaacgc cagcttgaat
     5941 tataactggt aataacactg cgatagcatt tgcaaattta gcaatcaatt gagtgccact
     6001 agctatcaaa actggtattt tagaagtaat tccttttaca aggccttgaa taatgccagg
     6061 accttttgta actgcggtgt taagtagctg ctcgatttgt gcgccaaact gactattaat
     6121 caaaccaagt cctgccacca caagacctag aatagcggcc ggtcctatgg ccgccagtgc
     6181 taaactcaca agactggaca ttgcgcttgt catagtccca agcacagata gcccacgccc
     6241 tgctgcggta gcaaaaacgc caggtaatcc gcttagagtt gccgcaaagg caccaacaac
     6301 gccgctggca ctagctatcc cactagaaat tatgccgcca aacgccccga cagaagtccc
     6361 taagcttcct aaagctagac caacttttcc gaatagagaa agcaaaggca ttatcgttga
     6421 tatagcgcta gcggggttca tcactgccca aagggcaatg actttagggg ctaaagaagt
     6481 gatttttgct tttagattat caaaagcctg ctctgataat tcaccagtat gtgcaaaatc
     6541 tccaaaaaca atattaataa gagcaaacac ctctttaacg ctggcgccta atgggctaaa
     6601 gtcaatattg atagactgtt ttagcctagc gaatgctgca actgcatttg gaataagaga
     6661 attaatcgta tcaaaaacac tggttattgc tggcttcaga ctaagaagtg tttcagcaat
     6721 ggtcttcatg ccattagctt tagccgcttc atcaaaggct gaaatcatac ctgctacgcc
     6781 ttttacgacg gcggtatgta cgttcttcca tgcagttcgg attccaccag ccgatgattg
     6841 ggccatctct gcaaatccgc cttgggcatc gttaagctca atcattttat ctgcgaactc
     6901 ttgtgcagtg attttgccat cagataaggc tgattttaaa tcttgtacgc catttttacc
     6961 aaaaccgaag gcttccgcca ttttagagat taaacctggc gcagcttctg atacagagtt
     7021 aaactcttca gcttgaattt ttccagaccc caacgactgg ctaaactgcc tgagtgcttg
     7081 ctcagcccct tcagttgttg ccccgtaacc gatcattgcg ttattgaagg cgagggctaa
     7141 actagtccct ttatctaaac ttcctgtggt tatggcgagc tgttgagcgc tttttacagc
     7201 actgtctaga ggagttggca gaccttcaat tccttttgat agcttatcaa ttgatgcctt
     7261 agattgttca gcagaatacc caaatagcgc catcgttttc ggaaagcggt tcatggtatc
     7321 aacgcgacta accgccccgt ctattgcccc agtaatagcg tgcatagctt tttgagcaac
     7381 agccattaaa ctaaaggcct gcacgatgct catcactgta cttttgagtc tctctccagc
     7441 agaagaggta ttggcgaatt tctggcttat tccattcaag gaagtagccg cagaactaga
     7501 cattctgcta aaaccattgc taagactgct ccctatttta cttgataaat tagctaaact
     7561 tgaggtcagc cgaccaaaca aactagtact cactttgttt gcgaaagcag acgccttagc
     7621 tgatacagaa ctaaaaaaat tattccatga ctgtaaggct gggttcaaga cttgctgacc
     7681 aagtgaacta gaaatcttcc ctccaacaga ctgtatagag ctattcaggg tagaaacgga
     7741 tgaggcaatt tttctaaacg ctgttccgaa tggtcgcgga agcttgcctg cgaccgtttc
     7801 gaatattgca gataagttat taagcttact acttgccctc tgagttaaga tatcaactcc
     7861 agtcgcagcc ttggcaaatg cagatcttat cttgccaata cccacaagat tctgaagttg
     7921 catttttgtt tgattaatga aaccggttaa gttaccccgt attttgtcaa taacacttgc
     7981 aactggaata atgatttttt gaaaaccatt ctttatgggt tcgggaattt tttcgccaat
     8041 ggaagctgct atgcgttgaa tttcaccgat gctcagtttt aaaccagtag cgtaggcaga
     8101 gccaagtctc ttcccgagcg attcgccgtt gttcgccagt tgggccatga tttgtccaat
     8161 gatttgaacc attttattac tactattaac cgctgtatct tgggcttttc tgaaagcatt
     8221 ctgagtcgta ctaacaatac gagccatggc ttgctcatag tcctttgtgt tggcaccaac
     8281 atcagcgaaa atagaaccat caaatgttcc tggcatctac tcctccttat ctatctattt
     8341 tgaaaatgat tattaagcat ttgtattctc tcaacaatac tgctatcact atcggcttgg
     8401 ctacggctag ctttttgata cgatcttttg atagttagcc tatgcttatc gtatttgagc
     8461 ttacctacat caaccttttt agcatttaat gtatatctaa gctttagaga caattcagag
     8521 aggctctcgc gctcagcaag ctgcttatac tcaagcccct ccataatagc ctctagctcc
     8581 cacttagtac atttatagat agtatcaatg tctgtgagcc ctagccgtgc gcaatttact
     8641 aagatactgc gttgctcatt cttccaatca cgtcttcgat aatttggatt tgagttgcgt
     8701 ccatatcgtc cttcgctttg agataacgag ctgatttctc catgttttcg atatatttca
     8761 aaatcttcgc tctgaaaaaa ccagaatcaa ccatttcttt ttcaatctca gcaaacaacc
     8821 cttctgttgt tccttcttca tcaacagatt ctgcaattgc atctagaatt tcatcttcag
     8881 ttagcgcttt ttttccgctt cccgcagata aacgcacaag gtcaacaatg gcgctttcat
     8941 tacgctctaa gatattgaaa aacaaagcac caacaccatc tgcattgcgc tctcctgttt
     9001 ctgggttaat tgttcctagt ttattattga tcttaaacat agttttaaaa tcaaatttaa
     9061 tatcgatatt tcgttttgct gctgtaaatt ccattatttt atctcctttt taaatcaaaa
     9121 tggggtatca gttgccaccc ctgtgtgcta tttagtgata ttatcgtagt cgccagtagt
     9181 atcacccgga ttttgatagc cgtatacatt ttctagcatt tcaatttctt ctttcgtgag
     9241 agggaattta ccatcttgta aggcccctac aatgttagcg gtgtaggaca tttctactaa
     9301 gtctgaaata ccagtaccgc gttcgatttc gtcaatcttg gcgtacccaa acttagcagg
     9361 gtaaacatct ttcttgggtc cagtcgattc aggaatttga atctgttctt tgacactttc
     9421 gtcggcaata acttcccaaa ttttgataga tttacctgtt ttcttagctt cctcgatgac
     9481 agcaacagat ggatctgtcg gtacaaagta cgttgtcaaa tcaatagagt gttcatctgt
     9541 agccttctca ataacgcgac cttgttgggt ttgctcatca atgtattcac cacccatggt
     9601 tgtagtacca tcggtacgat aggctggcaa cagagcctga cttttctttg gtgcatcaac
     9661 tgattgtata aagtaaaaaa tcttttttcc tacaatcggt ttacctgttg taatttcaat
     9721 agttgttcct ttttttgtgt ttgccattta ggtccccttt aaaatagtgt ttctgtaatg
     9781 ttgatagcaa ctctatagac ttctcgtcct attgaattat ctaccaaaat ctgagccttt
     9841 atttggttat ttcgcccaag cagtctaagc atgcgagatt ttatctcttc tgcatccaaa
     9901 cgactatcgc caggtaagaa agcatcgata ttcaggctaa aatcatcaat aactgctcca
     9961 gtttgagctg tttttgacaa gtctgatata tttgtaccta caacaataaa aggctctaaa
    10021 acgtctgatt taggcaattt aaaatagatt ggtatgtcta aaactcccaa tctatttttt
    10081 acctttttta aatatagtgt ttccagtgag taatccatgc atcacctctt aaacattttt
    10141 ttgatattag ccattagcac aggccattct tttctcaggg cagggtctaa aaacgattgt
    10201 gcttccattt tacgagtacc taattcaaga taaatagaat ataaagcagg agaaaccaat
    10261 ctatagtgta agagtcgttg ttgctcactg tagatttgag ctctcagcca tccagtgtca
    10321 accggggcta gtattttagc ctgtctctca atcctagcag ctgatttact aagctcttta
    10381 tctacagcga ttcgtactga cttctgcttg cgctcaacgc tgcgtaaaaa cctatctagg
    10441 cctctcatcc gataaataag actcatacat aaataaccgt gctattttta tggtgtgcta
    10501 gtccctttat caacctcgat tttcccttgt agataatctt gctaaagccg tcgtaatggc
    10561 cttgcaagtg caacttaaaa gcattcaaat catatttacc aaatagcccc atctgttcag
    10621 attttgtgaa agtattttcc atacagggga ttttcccgct aggtttttca acagttcttt
    10681 tatctagaaa atcgtcctgt tcatcgacat acactaagat tactctatct ttatagatca
    10741 ttgtgtatct cctaaataaa tcttgctacc cctttgcctg aatatacctt cccaatagca
    10801 gcgcttctga gtgttgattc atactcttta aggtaactgt cccacttaaa agtctttcct
    10861 tcttcgctat cttcaacggc tccttctgaa ttaatcctat taaaccgttt aatagcaaca
    10921 tcacggacaa taaacctcaa tctatcagga attttggtga tttcagtttc tgagtattca
    10981 ttaagtttag ctagcacacg ctctttactt tcatatatag caagggtgat gagctcatct
    11041 tgcgcaccat cacccttgga aatacctata aagagtttga tatcgtcaat aagttgttta
    11101 tcacccatat aaatagcctt taaccaccaa tgccgggtac agcagcagct tcgattgttg
    11161 cctctacaac cccttcagga atttcagcaa acagtacatt cgccccaaag aaaacagatt
    11221 cataggtaag attagaaagc tgacgattac gagctgcagc aattaaacct gtctcatcag
    11281 taaaatcagc aaacaagccg cccaagtctc cccctttaac atttaaagat gcaaaaacta
    11341 gattttctac agccgttgag tagattttac cctctggcac agatggcata acaatcacat
    11401 tttgcatacc caaaaagttc ttaagcaatg tcattccaaa aacattagag gcatccgcac
    11461 ctactttagt atctccaaga tagttagcta cgtctaaagg agagacaaaa gaaacaagcg
    11521 gggaaccctc aaactcatta aaagtagcta gcttagccca tgatgcagac agcgcttttt
    11581 gaaggccaac gcctttaact tttgttggtt ttgttttgag gaatgtaaag aatgcatcct
    11641 taattccatt ctgaagctca cgcataatgc gcttatctgc ttcagtaata gcacgagctg
    11701 caccatggcg agcaattgcc tcagctgtag ttgcacgacg tttcttgaac cacttcactg
    11761 tatagtcttt atctttagtt cgagtaacct tagacagagg gattgtttcc ccttctccag
    11821 gatcagtttg atctaaagtc acttcccact tataggtctg aatttttaga tcgttagtta
    11881 atgtttcacg acgagtaacc cctagcaatt ttaataaatc attaatattt ttggaaaact
    11941 tgttaacaaa atcaattgat ttaatatctc ctaagtccgc catagtgttt aagttttttt
    12001 cagccataat attcccctct taaaataagt tacgattctc agcaattaaa cgcatacgtt
    12061 cgtcgtcatc ctctatcgcc atgatgtcag ccttagtcat accgaccgag ccatttccag
    12121 ttcgtggcgg tttctgagtt aaacgatcgt taacacgttt ttcaacagct ttatcaaaaa
    12181 tagtttgtaa attatcaata ttggccttaa cctcttctgc agtagtggct aaaacaatat
    12241 caataaaatc caatggcaat cctttctcca caagcaggga atgcgtctca atgcgcatct
    12301 cacgctctgc tactgctttt tcacgctctg cgatagcatc tagacgtttt tgttcctcct
    12361 ctttagcgcg ctcatctttt gacaacttgg ccaaacgttc accttctgta cgagcttttt
    12421 caatagctgc ggattgttca gattcccatt tagtgcgttc agcagccatc atttttgaga
    12481 tgtctgcgcg agtaaaagtt cgctcatatt catgcttagg atattcaaca gcttcttttt
    12541 gagtgtcgac ttgctcagtt gtctctgttg ttacattttc ttctgccata actttctcct
    12601 agtggttacg ccaccaaccg atagtctagc tttacgtcct gcgacgaaac agtgtagctt
    12661 ttagtgtcat caacaaagtt tggacacaat aaaaagccgt attgctacga ctttggttta
    12721 gatttgtaaa gaggtcaaat tcgacacggt taaactttat ttcccccact tccgtttgta
    12781 gtttttctta atatagtcaa ccgtgtcacc aattgccttg ataactgatt ggttatctaa
    12841 agtagcagct ttaacagccg ctaactcttc gtttgttgcc agagcgtttc gttgaacgat
    12901 tgattttagc tccatgattt gtttgttttg atttttaata gcttctgctt gcatggcatt
    12961 ctctgcaaca agcatcacaa ccgctgtttc caatttacgt tttttcttaa tgcgcttatt
    13021 cattgtttta tccttctttt ttcaattctg caataattga cttaaccgct attgctgcaa
    13081 tgccaacaat caatatgagt accaatacac ctagtgccac taataccatt tgccaaataa
    13141 acatattttc ctccttgata gttttaatag ggtgatgtat aattgagata aagaaggatg
    13201 atggtctaac gcccatgaag cagtttactg tggaggcggt gggtcatcct ccttcttttt
    13261 ctaatacagc taatacctca tctttatttt tgataattga tatatcaaga cccctacgat
    13321 ctatcatata aatatgttct aattgcccca ttatctcttc aaatgataaa ggggtttttg
    13381 ttatatcaaa aatgatatta gttgcctgct tttttgcttt tcgtagattg ccatcaatga
    13441 cgtttttacc cgaacctgtg atttctttta gatcaaaagg agctacatca actaaataat
    13501 caggagtctt gatatgttca ggggaattaa ctcttggcac catgtcaact tgcaatcctg
    13561 tctttttgga taaccaatta gcaactctat attcataatt cgaatgatca agaacgacac
    13621 tatggccatc tactttgtaa ggagtgccat tttttacgta ctcatttagt agtgacagtt
    13681 gtggtttatg ctcatttcca tctatccaat ctgaggtgac atccttaaaa tacttagtgc
    13741 ttttatcatc aattggttct acttcaatac ttagctcatc ttcatcagga ataatagttg
    13801 ttctgcagtt gaaatgatag ggtgctacat taattccagg ctttagctca gataatagct
    13861 ttcttttgtt ttctttagca attgtacggc atatctcagt tgtcctgtca tcaagtctaa
    13921 ctaaatcacg ataatactta agtcctgcat tcaagtagcg cctagcggta gcattattaa
    13981 tcaccatagt tccatcagtt ctgattagtg tttcagccct gtgattagca acattaaatc
    14041 gcttagctaa atctctggcc atcgctctag gatgctcgcc acgaacaaaa ccttgtttta
    14101 atctcttttg aagattctta acaagattgt cagtattgcc ccacaactgt tctgaatagt
    14161 tataaccatc aaacggggtt ctaaccagtt cttctaaaac tggaccattg attgtccctg
    14221 accgtccacc cattgctttt ttataagcat atgaggcaac tttttttaaa tgattttcaa
    14281 atgctgaatc aagtacacct tttagtatcc ccgcacgata aacaagctca agatttaatg
    14341 catccatcct tgtagctctt gctgatacat actgctcatt aagtcgtttt agcagctcag
    14401 gatctttctc agcttgttta cgatacttgt tagcattagc tacgtaatct gataaatctt
    14461 catgacgtag ttttttaacg acatcctgat aagtcatttt gttctcttca gaatacttag
    14521 tataaaaatc aaacaattcc ttttgtaact caaaagcctg ttcattatat aacttctgca
    14581 gttctgaaaa gacatctaaa tcagttctgt ctaaataact tagaatatct tcttgacgct
    14641 tttgccagta attaaggctt ttctgccgtt ggttcttctt gaccactagc atcacctacc
    14701 aatctaggct ccggtaaaga ttgcttttta tcagcttctt ctttcaagcg tttaagctct
    14761 gcttcagcat ctactcctgt gacagtattt aagatttcaa agatagtctg atcgctaaca
    14821 atgccataaa gattttgtgc agctgtaaca atttcattat cgttttgagg aagattaggt
    14881 gtgaaaacta tactcgtatc atttacaagg ctatatgtag ttgcttcatt ccctttgatg
    14941 gcccagatat tagctgctaa gcgtaagcgt cgcattaatc cttttttaaa caacctctct
    15001 tgcttctcgc gatagttgtc agaagccata agcttatact tcattgattc accagattga
    15061 actcctgaaa atttcatatc ttgtgtatct ggcgtaaaag taaacctcaa aatgtctgca
    15121 actaatctat ttttgtaggc ttcgctaccg gcggtatcat actctttttt gagaaagtac
    15181 gcttgcggtt taacgccatt tggattagga ttatcgtcta aaattaacac ttgggctttt
    15241 ttaaacccaa ttgagatcgc taaacgacca ttaggattta atcggccatc atctaagtag
    15301 tcattctcat cagctcctgt gtaagcatta ccagctatta caagcaacgc attgactgaa
    15361 tcttgttgaa agttagcaag ctctgattga gataaatcat aggcgtcaat attatcaagt
    15421 acagactcat aagcccccgt tcgctcctcg ttattagcgt attcgttgac tggtacacct
    15481 ttaaaaaaat gtccttcata atcttttaat cgcatacctt ttgtttcaag gttatagtct
    15541 tcgtaggtat aaattgtgtc ggaagtatat gctttgataa tctgtttacg tttacctgag
    15601 ccgtaatcta tgtcgtagaa atgaacggcc atcaacgaat ttcgctggta tgtatcatca
    15661 tagataacaa aagtttgctc ggccgggagc tggtagagtt ttacttcggt ttttttgtca
    15721 tctattttct caacagttaa cagctcgtag gctcttccat aaattgataa atctgttttt
    15781 attttgacgt tgtggtagtc ctcattgttt ctgaccgaca taaggtcaat agctgcctgg
    15841 aggtctttat tttcattttt gtactcaacg ggaacgccaa gcatataacc ttgctcaaat
    15901 accgtaatat acttagcaaa atcacttgca atacgattat ccgctgcgta tttatctgtt
    15961 ttagcaggtc tatacttgat gttattatcc ccaagatagt atcgctttaa ctctttcaaa
    16021 cgctctaatt gttctgcttt aaaccttgaa atgtaattct taagttgatc tatccaaagt
    16081 tttgattcat agtcaattgc ttcaaagtct tcttgcagca taataaattg cttattagca
    16141 ttctcattaa aacgagttcc tgctaaaaat tgtttttctt ccaaagtttc acctcattcc
    16201 taaaaataat atttagcatt tttcatgcgc ttacttctat ccgccgactg gtatattctg
    16261 tcttgtacgg catatcttat ggcatcaatg cagtggttat agctgtcaac tggttcgttg
    16321 gtatactcat tagtcttctt gtctttcttc caagtgtaat tttcgagttc ttcaatagtc
    16381 ttgacacacc tttcatcaac aatccaatca tattgaagca aatactgtat tccttgcata
    16441 acggttccag gccctttggt aacatcaatc attctaggaa tacctaaatt cctcagctct
    16501 tgattagatt tcttttcagc cgaatctcct ctgatttctt ctttggcata gccgaggtcc
    16561 tttatagcat ttgctatttt gtcattggtc aaattcttcc tgacatattc ctctaagatg
    16621 tataacttct tgtttgcgtc atcgatttta acatgcaaaa gtgccgaagg atcattgata
    16681 aatccatagt ccaaaccaaa aaaagaaggc aagtgtgata acttgtcttt gtttaatatt
    16741 tgcttgtcat atttgggaaa aattagttta tcaagtgtag caaactggcc aagagcatat
    16801 attttgtaat aagcttcatt cctattggct agttcctcga tattttctct cgtgacatca
    16861 tctaagaagc ggttgtcttt ataagttgtt tgatagacaa ctgtattctt aggtgtctta
    16921 acgaagaagg ctttataaac ccagtttact tttgataccg ggttaaacat caaatatatt
    16981 tgcttctcta gatgtttctt atctcttaaa cgcaaggtca actgcgtata atcatcaagc
    17041 gtaaactcac tagcttcttc cataaccaca tcagatatac ccttaattga cttaatcttc
    17101 tctgggttgt ccataccctt gaaaatgaat tctgcgccat ttgggagcgt tattctaaaa
    17161 gccgacatat ttatcttaca tttatccaag atgccgaaat acgacaaatt agacatgata
    17221 tcagcaaata cagagtctct aacagttgca ccgacttttc tgagaactaa tatctttctg
    17281 ggatgtttga atttagggtt aagtgctttt aaaattatct tttgaaaaac accgtgagac
    17341 tttccgctag acgccccacc ataatgaact tccgtgaagt tgctatagtt gtaaagtttg
    17401 tcgtagatat gtttgttaaa aactttgcta ggatgcttga tcacgatatt aattttaggg
    17461 cgctgtttag tcgtcatccc actcacctac gttaatggtt acatctgagc tgacatccat
    17521 ttcaaccttg tcagtaaata acctgtaccg tttgcctagt agctcagctg ccttgattct
    17581 atccttggca ccaacatcga tgtcaactat cttctgacca aactctccaa cgctaatgag
    17641 cgtcttttct tgttggtctc ctcgcataat tgaagtgaga tattgtagga cttcttcttg
    17701 cgtagcaatc ttttcagatt caagtttttc aagccgctcg tctatataag ctttaatgtc
    17761 aggtttggtc aagttttctt gacctattga ccttgctgtc tttttactat accctgcttt
    17821 aatagccgct gctgtcgcgt tagctgagat gatgtactca tctgcaaaac gcttctgttt
    17881 tagggttaat ttactcaatt ttccatcacc tccaagcata gcaaaaaggc aagacactat
    17941 ctgccttacc ttcaaactca tactaccaat ttatcatcaa aaagatgaca attccataca
    18001 tttttgtgtc acattcctat ttttttggaa aatatttcta gaatccgctc tcttttgcgg
    18061 taaatagact tacgcgacag atgtcttgta taggcaattt cttcccaagt gttacttgaa
    18121 ccaacgcccc acctaagatt aaaaatatca gttagttctt catccaaaag atttaacgtt
    18181 gcaataactg cttctttgaa attggataga ccctttagtt ccctatctga atcccacctt
    18241 gcaaccacat cctcagtaac ttttgaaaca aaatttgctc ttcctccacc gatattttta
    18301 tctaccgcag tattcatatc agtttgtagc tcaagttttc ggagtgcgat cttgttatca
    18361 ataaaacgat aatcaaacag ccattcgtca aaagctttta actgtgcatt agataatctg
    18421 ctcactaagt tttacctcct ccagagtcat cttatacgtc ttcctctccg ctttaaatgt
    18481 tcgactggat tttccaccag aacacatcca catcaagtca aacgctgccg cttgtgcttt
    18541 atcaaatctg tccatcctta tcccccattt ttcgtcaact ctgcaattct ctttgtctgt
    18601 ctagctctat catcactagc acgtttaagc tgcttttgtg tcctacttag ctgagcacgt
    18661 agtccgtata tttgcggctc gtagtaactt ttaagtgata tgccaagccc tgatacgaca
    18721 atcagcagca taactgttag tgcagtgata atgatgtttt tctttttgat tgctttgtct
    18781 ttttttacta actcataaag caagcaatca atcatctgtt cttcagtcat tctcccgctc
    18841 cctagtatat ttttctttaa ctgttgcttc gcaagaattc caaaacttca acatgtccgc
    18901 ttttcgcgta aaggttttct cttcaaactg aggttttgcc tcaaaattct tttctctacc
    18961 cgtgtagatt ctaacgacat attctttttt catctagacc cctaactgcg ccttaactgc
    19021 ttcaagtaag gcgttctgat ttttttcttt gccttgtaaa atcctaagta ctttttcatc
    19081 aactgtattt tctgcaacaa tgtggtgcac gataacgggt tctgtctgcc cttgtctatc
    19141 taatctggca ttagcttgtt gataatattc aagactccat gttagcccaa accaaacaat
    19201 aatatgcccg cctttttgca gattaagccc atgcccagct gattgagggt ggcacagaag
    19261 aattggtatt tttccggaat tccacttgtc aaccgacgtc agctcttcag cctgaggaaa
    19321 tcgtttctta agtctttcaa gatcatgttg atactggtaa aaaactaaga ttggctggcc
    19381 ttggctttct tcaacgacat tctcaagcgc gtcaagtttg tcgtcgtgta tagcaactgt
    19441 tgctttatca tcatcataga tagcaccatt ggccatttga agtaatttat tggccaaaac
    19501 cgcagaatta gccgcagata tttctttatt tttaaactcc aacaccaaat cagcttcaag
    19561 ctgtttgtag gctttcatat tagataactt aactgataca acgttgttgg ttcgcggcgg
    19621 taacttgaga tagtctttag ctttcatgct gacacagatg tcctcaatct tgttatagat
    19681 ttctgcttct gcaccatccc taagtgccca actgtaaatg attaggccat tacgcttatc
    19741 aggaacaaaa tacttgtctt taaatcgagt ctggctcgtc tcaagcctgg cgcctctgtc
    19801 catcagataa atctgcggcc acaaatcaat caaactgtta ggcgctgggg ttcctgttag
    19861 tcctacaaga cgttggactt tcggtctaac ttttcgcaaa gccctaaacc gttttgactt
    19921 actagactta aagcttgaca gctcatcaat aaccacaaag gtaaacggcc atttagtctt
    19981 gtagtattca acaagccaag taacattctc acgattaatc aaatagatat cggcttctgt
    20041 ttctaaggct tcaattcgtt ttccctcact ccccaaaact ttagagtagg tgaaatcaaa
    20101 atgccatttc ccaatctccg ttggccacgt ttcttccgcc acttttttag gagctacgat
    20161 taaaatctta tgatcctcgg aaaaaatatt ttgaatctca tctattgccg atagtgttgt
    20221 cagcgtttta ccaaggccca tgtcaagtaa aaggccacaa taagggtgct ctactatcca
    20281 tgtcttagcg tattcttgat actcatgcag tctcacaccc agttctccat ttcttttaag
    20341 gctatgtcca ctgattcgta ggagtcaaca acccaaacgt gctgcccagc cttttttatt
    20401 tttttgtgca ttgcaacttg actgggtctt ggttttttac caggcgcttt gacctctaca
    20461 aaaaaggttc ccgtgttcat gacaacaatt ctgtcaggca ctcctatcgt ccctggactt
    20521 gcaaatttta aacacagccc ttttgttttc tttttcaaat aattttcaat gtctttttca
    20581 gtcctcatct ttcctccttt ggtcaataaa ggtcagggtt acgttttttt caacttatta
    20641 attctttttt atatacgtgt tttatatatg ccttatttta tatatattta ttttttatat
    20701 ttatatttaa gttaatagaa gaaaaaacat aactacataa ccttagggtc taaactattg
    20761 ctatgaaagg ttttttgagg ttgcataaaa gttacgttag ttatgtaaat cgacttaaac
    20821 aggaaaggtt tttcaggaaa gttatgtagt tacgtttttt tttaacttat aaaatttttt
    20881 ataagtctga attctgcgta actacgtaac caaaattttt gaaatcacaa ctcaacccca
    20941 aaaacgtaac cctttaaaat tctcctttta tcctaaaacc tatccaacat cttacggtct
    21001 tgccccccat ttttgcgttc ttattttcaa aattcagttc attcatcctt tgtgtaaatg
    21061 aatttctggc caaaggtttg tagcctgaat cctgacaata gaatttatag gctgggtaga
    21121 cgtccctaac aggaactttg aagtcttcgc taagatcgca ctcatcttca aggaacatag
    21181 ctacgacatc gttgcctttt tcccatttct cgacacttga cctcatgctg gcactaatac
    21241 tgaaatctct cttacttaag gcctttctaa gcccctccat cgctctgtta aagataccag
    21301 gcacctcgct cataatctta tctagcgggt atttcgcctt aacttcctgc gttaaaacct
    21361 tatccatctc aaggatcatc atgcggcgct taagtccccc actgaaatct cgcataggtg
    21421 ggagctcatt catggcaaaa gacagcttgg cataattgta aaaattaata ggctctttgt
    21481 ttttccggtc agcgtgtatc gtatcttccc ccgtcaacat tttaagcgtt gcgccatctg
    21541 ctaagtattg aggtttagca tcggtatcga agttggcggt ctttcgatat aatccgattt
    21601 ttgcaaagcg ttcttgcatc aggtactgca gtgtcacggc tgaataatta tcagcaccta
    21661 tcatttcacg taaaatatta atcagtgttg atttgccagt acctccgctg ccatagatga
    21721 ataacatctt ctgaatagtg tattcacgat aaaagttata gccgaaccac tcaaagatga
    21781 aatctatatt ttcagctccg acggtctctc taagaaaacc ctcaaaggtt tcacaggtcg
    21841 cctcggggtc atagacaacg ggatggcttg accttgcatg cacttctgga tcaaacttag
    21901 tcttaaagct gttatccctc aagtcataga ctccgttcgc tagcactatc ttgttaagat
    21961 cactctcggt aaacacttcg cttgagaaag cctgtgcttt aatcgctaca atggtttcgc
    22021 taatgtgcct aatcttagtg attttaccga gtttcttagt tgagatataa ctcttcaaat
    22081 actcctctgc gtttggcaac cagatgcctt ttttagcgtc gtagcgtaaa aattctaagc
    22141 cgtcccaata aattggaacc tccttaataa tctgcgttgc tagcaaataa ctattgacct
    22201 ccggttcgcc cctctcatca atttcaagcc agcttctgtc atcttcgact ggtaactctt
    22261 catcgaaatc gcctaaagcc tccgccatta gatagtcttt aatttcgggt aagtcagaga
    22321 caaaagcatt catcgcttta cttgacggta gcttattagt aggagtatta tctttagcct
    22381 cgctatcttg ctctccaaat ttatggatac gaacaaggtc gtatgcattt acaagcgtat
    22441 cccccacggg atctgtcccg tgatgactat aagcgaagac atcatcatag ataactaagc
    22501 catttgcggt tgagccctca gtgtaggtgt acctatcagg agtcgctcct tcttcataaa
    22561 cctcaggtaa gaacgttgca atggcctgtc taatgtcata gttacgacaa aaggctccaa
    22621 taagtccttt tttactaagc gggtcacctt gttttttagc ttcgcgctgt cttttgacag
    22681 cgtgcgtcgg gctttcgggc cagaagcttg agtcgtgcca atccggatat gtatccagca
    22741 cctcgtcaac actcagaaaa gcctcgtcgt tatatttaaa cgtaaactct gcatctcttg
    22801 agtgactcgg ccagaacatc aagcgcacgc tttgataagt cgtgtcatca aagtttgaca
    22861 tgcctagttg attagccaaa tatctagcga ctggttcata ttcatcaggc atcattaaac
    22921 ggtctgtagg gataataaga cggtacttag cagctttttt tgagtggctg tgggtactgt
    22981 agagtacgta ggcataatcc gcaagcaggt ctagcctatc taggaaatct ttacttgggc
    23041 tgtctgcgtc aagcgcaacc aaggatctac tttgaacgtt ttcatttttc cgtttacctt
    23101 gctttagcca tccaccgaca aagcccccta cgtcttttgc ttgccctttt tctgctcgag
    23161 acatcttctg gtactccgca aacgtctctt gtgtgactgt aggtttctct agcctctcaa
    23221 ccagctcctg ccaagttagc gtgatatttt tccatgtctt agctgttcgc gaactacctg
    23281 ttgcgatatg aagctcttgc aggggagaag actttactat tagtttttct tgcttcatct
    23341 atctaatcct tcatataata ctttgttatg tagccttcgc tatttaaagg aagaccctcc
    23401 gcccattcag gggcctgagc catcaaatca ttaacctctt cgattgtcag gcctgagcct
    23461 tcgataatag cctcgtcatg aacgtggaaa acaacaccat ggccggcagc ttcaattctc
    23521 agaagcgctt cggctagaat atccctagct gtcgcctgaa cgatattttc gacaagctta
    23581 cctccgtaag tctcttgcgc tgtgaagtag gccttatctc cttggccctc atagacgatt
    23641 ttgtctccat agtcgcccgg ctcaaccttg gctcttgcat aagctaagtt cctaccgcta
    23701 ggcaatgtta taaagaggaa acctttacgg tatctaaatc gtagcttccc aagtcttaca
    23761 ggtgctctcg atttgatggc tttgatggcg gctctttgta cgtctttcca aaattggacg
    23821 attttcttat tggccctgcg ccagtcatca actaaccctt gaagctcttc ttctttgact
    23881 cccatgttta gagcccccat ctgcttaagc gctccaggac ccccttgata gccaagtgct
    23941 aactctgaaa ttttgccctt ttggcgtagt tccttgtcaa tctcctcaat tggaattccg
    24001 aacatctgac tggcagacgc ctcgtagatt ttcccgtgcg tcgaaaacac gtcaagcctc
    24061 cactgctctc cagcaaacca cgcaatcacc ctagcctcaa tcgccgagaa gtcagagaca
    24121 tagaaggtac agccatcttt agccacgagg gccgttcgca cgagctgctt taaagtgtca
    24181 ttaaggctat cgtataaaat ctccacagca tcaatgtcac gctttttaac atactctcta
    24241 gcatcatcta gatcctttat ataattccta gctaagttct gtacttggac aactctgccc
    24301 gcccatcttc ctgtccggct agccccgtaa aactgaagta gcccatgaac tcgtccgtct
    24361 gagcacctag ctctttccat agcttcatat ttttttagac ttgacatagc ggtttgtagt
    24421 ttaagttcta aaactctctt aagttctcct tcggccgtct taagctcctt ctcaacatct
    24481 gctttagtca gcccactagc cgaatagcca tgttctttta gccacggtag caactgcgtc
    24541 ctgctattag gattatcaag tcctgttaga gcttttagtt ccccagacaa actttccatc
    24601 ttaacatctt tacaatacaa ggccgaagca actaactctt tatcaagcgc cacgcctctg
    24661 tcgttgattc tctggtcaca ggcgtagtaa tcccattcac ggtcgtgcac aggaactgac
    24721 tctagttttt cggcgattgc catctcaaca acaacgtctt ggatgcagta gtcaataaac
    24781 atttgccact tttcgggggc gtgttctggt aaatttctag ttctcccacc gttagtttta
    24841 cttggtttgc aaggcaggga aaagtatctg attaagtttt tacccgaggt atctttttcc
    24901 tgcgctaatt ttaaatacag cgcacacttt tccaagcttg aaggcagacc caactcttgg
    24961 gccagcacca tggtgcattg ccattggcaa ggatctagat agtaaggtag gccgaggtaa
    25021 cgactgaggc aaactctttc gaattgggca ttaaaggcgt gctttcggac tttatcatca
    25081 aataacatat ctttgatgtc ttcaggtaga gactgccttg tcaaatcaag gcactctact
    25141 tctccgccat ctatagagta agcgaaaagt aaaatctcaa aatcttctgc gtcagcgtac
    25201 ttgtaaaccc catttttgat gtcattcgaa ctataggttt caatatcaat atttaaatgt
    25261 ctcatacctc tcctttaaaa atgaggagcc tctaaagagg ccctctgcta taaaatatcg
    25321 tcttcgtcct cttcttcgtt ccactcgtca aagtctgcat cagctgacga acggccgcca
    25381 aggtagtctc ctttagcaac aatttggacg ttgtttaatc cgcaagagat acctttgttg
    25441 ccagctgtgt tataagcgta agcattaagt gatacacggg catagacgcc ggagtagact
    25501 tcttctgcgg aatcaacaaa atttttatac ttatcaatga tttgaggttt agttttactt
    25561 gacactgaca tgaacatgtg accagtgtac tctgggtgct cttcggtatc catttcttcg
    25621 tcaccgtcac gaagcgttgt cttaacgcgc tcccatttaa cccctttgag tttattgtcc
    25681 ttggcagctt cataagcagc tttctgcgcg tctttaattt tcttgattgt gactttgtct
    25741 gtttttggaa ttaagataac tgttgaatac ttagcctctt ggccttcaaa ggctttaggc
    25801 tctagtaaag ctacatagct taggcgtact tttccggtca ctactttagt tgtgtttggt
    25861 gttgttgtca taattatttt tctcctattc aaaatcttta attgcttgtt ctaaactgtt
    25921 tattgctggg cgcttatcct tttcagggac aagtacaggt ttgccctgtg gtttatcaat
    25981 tacttctgct aataaatcag caaaagtggt tttacctatt aacttttcaa gggctcccat
    26041 tgctaacagc tctttcggtt taaaaatctc atcgtcaaag ccgttatctt gtaaaatatc
    26101 aattgctttg tctttatcag tgataactcg attacttcta ccttcgacaa tcttatagcc
    26161 tggaacttct tttcctgaga gtgcttcttt caaggcatag gcttcaactg actcaaccca
    26221 cttcttgata gctgaggctt tgtcaaggat ctctgcgacg gcttcatcag ataaatagac
    26281 aggctcctga tagtcatatt tatcaattaa ttcccagttt tcttgcgctc ttggcaccaa
    26341 tttagctgcg acaggagacc actgcaatac tttttcactt aggttccagt caccaatacc
    26401 tgcatctgct tgagctgcca taggcaatac gacattatcc gcccagtaga gtagctcctc
    26461 cacgtaaatg tcaacagaac taaccgaatc taaacgcggt tgaataattg tcatcttgat
    26521 gcgatcaaag tcataaacca tatcgtagga agcatatgct cctagagcgt acagtcccat
    26581 ctgcgggttt tgattagcag acacaggcat acccttgcca tacttaagat caataatttc
    26641 aatgacccca tccgccaaaa taacgacatc cgaagtccca aaaccgccag gcacccagtc
    26701 gctaaaatca acccgttttt caagttcaat ttcggcgttc tcataagtat ttaggtgctc
    26761 cataacaata tctgtgtaaa gctccgtcat ctcttccatc tcttcgttgt agaagtctga
    26821 gttttcctta aaagccttgg ttaacgtgtt aaatttacgc ttggtgattt taccagactt
    26881 gtacatcagt ttgatttcag aaagctcatg ggcgcttgtg ccctcttgag tgtatacggt
    26941 gtcgcggcta ggatagtctg cttctaatct cggtagcata gggcaataaa gccatctgtg
    27001 agcactagaa gcagacagta gtgcgtgatt ttctactggc attagagagc ctccaacttc
    27061 tcaacaaact ccgcaaactg gtattcttca agttcaccaa cttttgcgac gttcatctct
    27121 ctcaagacct ccttgatgtc ctttgacttc ccttcttcaa ccttggcttt agccattttc
    27181 ttaatatcag ctaatgttaa agttacagac tcttctttct ttttaggagc tggtttttct
    27241 tcaacaacat ccttggttac tgtcttcggc atatccagag cttcacgcat agcatcgaaa
    27301 acacctgcca tgctctctgc tttaaaagtt acttcaatca ttgtgtttct ctctttctgt
    27361 gttataattt aagtgtgtat aattgttgac ggtttcctaa gccgtctttt ttgatgcaat
    27421 caatagcctc acctccccaa aagtccttta atatcaagaa tgtctttagc aacctggcta
    27481 cgatagtatg ggctatcatg taaaccttcc tcgtagtagg ggttaggcac aaactcccaa
    27541 tctccgcccg gcaactcaac ttcgataact tcgtcgtcaa taatttctag ctcacgttca
    27601 agataagcta gtgcatattc taaatagttc attttctttc ctcaattact tgttttaaag
    27661 ctgttagtat aaaaactgcg tccgctaggg cttggctttg ggaacaagag cccccccctg
    27721 acgtaaaata gtatttaaac ccgctagggt ttcatcaata aattttagtg atatattcat
    27781 ttctttttac cccacaaaaa ttcttgccat gacaacgttg cgcctttaaa ttctttctca
    27841 gccaacttaa caaagttcct cctatcctgg tcttctttaa aagtttcctt agctaatcgt
    27901 ctccaaaagg cttttctcgt cgcttgacgc tctaagaaag tttcactgaa tttaaaatca
    27961 tttccttgat aaagagcttc gtatttctcc acattattta acgaaggcag ctcaacccaa
    28021 agcatcaatt ttaaatcttg cttgatggca ctcaactgag cagataggat aggtaagcta
    28081 tctcgtcttt cagattcagg tttagctaat tctccctcga ttcgattaag cttactaata
    28141 accttttcaa aagttgtcat cgttctgcgc ctcctagctt gagaatttca ttaaggatac
    28201 gtattttttt ctttggaata gcttctgaat ttatccttta agctcagtaa gagttccaga
    28261 tcagatattt cgccagactc gtttaagtca agtaaagcct caactgtgct ctcaaaatct
    28321 gtcgcatttt ccagtagttg tttttgtaat tcccatttag acataacgtt ctgcactcca
    28381 tttcttgctg ttttctaaag ccacttctct aaaaattctg cgtttattct ctggcgagtt
    28441 atgtttttta atgacttcat attgcaccct agcgatgatt gctaagatga tggttattgc
    28501 taataaaaat aattctagtt tgttcatgtt atactcctct agcactcccc agcgcttatt
    28561 gtttcattaa gtgtttaatt tcattgacat cagcaagaca atacattctg tctttaccgt
    28621 ttttaaaaga tttaaggcca tagctttcca tgcgttttac agtttgccgt gagtagccat
    28681 attcagtgac gagcgttgtt tgattgaccc actgatttgc taaatctttt tcctgtatga
    28741 gcttcttaaa ctcatcaaaa agttcttctg ctatctgctt tttgagtaga tcgtaagtaa
    28801 gttgcgattg catggattta tcaccccttt cgtgatataa ttaagtaaat taagtttgtt
    28861 ttgagtccga ttcccgtcag actttttttt gatataatta tcagttgcct aagctcctct
    28921 tggatactgt tttgactaca gttccgtctt cttcgcattc acaatattga acaccgccgc
    28981 tattttggac ctccgtagtt gtaactacag agctaaaatc atagccttcc tccagttttt
    29041 ctaaacgctc aaaaatgtta ataaaaaggg catcataatt ttgtttttct gcgtctgtca
    29101 taaggttcct ttctagaatt gtgttaagca agtggttcgt gtatttctct tctatctgat
    29161 ttttaaatct gaaataactt ttaagacaaa acgatttgat gctggatctt tttttcttcc
    29221 agctaagata ttcgccacat cttgcggttc tttattatag gtaactgcta agtcaacttg
    29281 ttttagctta ttgtcaagca gatacttctt aattttttca acagcgactg tgttgtctga
    29341 catgcgttag gctcctttct agtaagtaaa tttatttaaa acaacttaac ggaaacgtta
    29401 ttctgccaac ttttaacaac aaccaaattg atttttctac ttgcatgttt ataatgcaag
    29461 taacctttta tgaaaggagg acttttcgtt tgtccgagtt tttgaaggag actgtgtctc
    29521 agtagaagat ggattcgttt gtaggttttc cttttgccta ccgcacttga ctagcaagac
    29581 ccaatagggg ttcctatatc ttcattggcg tcctggccgg acgaccacag aaatcgcaaa
    29641 tattagtttg agcagaataa tttccgtagc accattcaga tagcagctgg atggtgtttt
    29701 aatttgtaag caagaaagtt agtaaatttt cttaaaaata gttgacacat tacaccatat
    29761 aagataaaat gaaggcataa gaaaaaccta gttataacct ttataactct tttatattcc
    29821 gcagttcccc aactacttaa aaagatttgt aaaaagttta acttcgtttt ttactaacta
    29881 tcttacaaaa actattttac accaaatttg gtaaaagtca ataattttac accaaatttt
    29941 ctaaaatatt ttttgtcatg ctcggaaagg ttgatatatc aatgttttca acattcgaaa
    30001 aaataaagga actggcaaag aaacaaggta aatcgctcgg acaggtagaa gaggacttaa
    30061 actacggcag aaatacgctg tataaaataa agaactcaac tccgaacgca gagaggctag
    30121 gagaaatagc taactacttt aatgtttcta ccgactattt acttggcagg acagataatc
    30181 ctaagattgc gcaagatggg cacacttcgg tcgcaattga tctaaaaaaa gatgcagaag
    30241 aaactttctt cttcgacgga cacgaactca acgacgagga tatagacctt atcacatcta
    30301 tattggaaac gcgcatcaaa aatagaaaat agagaggaca gctctatgat gacaccagaa
    30361 acagtctgtc aggaaaaagg catcgattta gtgtattttg atggtagggg tacaaacacc
    30421 cctggaatgt ttaataaaaa acacaacgtc attgcgattg acacttatct tgacggtata
    30481 tataaacaca aagtcatcta tcatgaacta ggacatagag aacatactgc gagttattac
    30541 aagctaaata aagaaaaagc agagctacaa gcagatagat gtatgataca ccatctctta
    30601 aaagaagagc tatcccattg ggataatatg gaggatttca actacatcca attcatggaa
    30661 aaatatgaac tgacctcaat cgctgacgaa gtgatggtca aggaagaatt agagttttta
    30721 attagttaag gagataggca tggatatagc taaattaaaa ggatttgcca tagcagctgc
    30781 agggaaagct aaagagggtg caattaaagc taacgaatta agaaaaaaag cctcacaaga
    30841 aagcaaaata attctacccc ctgccctaaa tttaggacta ggaacaccaa cgaccatacg
    30901 aaaaaccata gatggaaaat attatattgg tttttattct gaaactcctg agctttatga
    30961 gtttgttaac cttcaatttg atggctcacg aattattgaa aaaacagtaa caaaagggaa
    31021 aactactcaa aaagggcgtt ctggtagtgt tctaggaggg gcagcaatag gtacagtttt
    31081 ggcgccaggc gttggaacca ttatcggtgg aatagctggt ggggctagaa agaaaaaagg
    31141 aactattaac actactgcca caaccacttc tgaagaaata cctgggaaag caacggtagc
    31201 cttaagaaat atacaaaccg gagaaattaa aaccttaaaa actaagctta tgcaggctca
    31261 gtacgtaagt gttaataatt tctttaaata aaaaagcccc acgctcaact ttggtcggtg
    31321 cgagcgtgag gcaatatgca atcaataaga agtaagcttt aaatagctca ttttcttata
    31381 ctctgaatta tatcacacaa aggaggtgat gccaatatcc tatctcaaaa tcagcactcc
    31441 ctagcgcgaa gagagaggaa aaaacaatga ttgaaaaata cactaaaaaa gatggcacaa
    31501 ctgcctatcg cttaagagca tatctcgggg ttgatcccat gactggtaaa caagtcagga
    31561 caactagaca aggttttaaa acagaaagag aagctaaaag aacagaggta aaactggttg
    31621 atgattttca gcgtcaaggc gcttggaaaa acaatgataa gactacattt gatgacgcag
    31681 ccagactgtg gtttgagcag tataagaata cagtcaaacc gtcaacattt ctggttaacc
    31741 aaaactacta taaatcaaca ataaaaccgc atattggtaa atcacaaatc agtaaaataa
    31801 cagttatggc ctgtcaaaac ttaatcaacc acttagcaca atatagcgca tgcgctagct
    31861 acatcagtgt tatcaacagg atttttaagt ttgcagtaca tttaggaatt attgagaata
    31921 acccaatgga taggacaata agggctagat gtacctatgc ccataaagaa aaaatgttct
    31981 actctaagga ggaattacta atctttttgg atattgttaa aaaagaagag agtctagaaa
    32041 tgttgttaat ctaccggtta ttagcctatg gtggactaag aattggtgag gctgttgcct
    32101 tatatgatac tgattttgat tttaccaata acactatcag tataacaaaa actttagcac
    32161 aaaccaaggc aggtaaggtc attcaaaatc ccaaaactaa aaaaagcagt cgcactatct
    32221 ccatggatca ggaaacaatg cgactggcta aggagtatat gaggcagagt gtcagaccgc
    32281 tacatgggtc ttttagagta tttaatctgc ttacaagcac ggttagacgt aggcttaaaa
    32341 gaaccgttga acggcatcat ctaaaaaaaa taaaccctca tggatttaga catactcacg
    32401 catcattgct atttgaggcg ggagttcctg caaagctagc acaagaacgt ctaggtcatg
    32461 ccaagatatc aattacaatg gatttataca cccacctatc taaaaatcaa accgataatg
    32521 tagctgagaa gctagctgat tttatcgcaa tttaacacga acgtagtaaa aaacgtagta
    32581 agtcgaattt ttggatttag aaacccattg atttcaaggg atttctaagg tgtgatgata
    32641 ttatagcata ttctgaaacc aattcccata aacgaaagag gccctatcat ttcataatat
    32701 ctccccactt aactaaatta tcaatgaatg ttttactttt taatttgatt cctacatagt
    32761 cgtgatacaa ctcatcaatg aactgacgaa gcttcttttt gatgtcttta ttcaatgaaa
    32821 tagttctcaa atcatcaaat gtgatttttt gaaatcgact caacaagtag ataacatttg
    32881 gatctaaatg attacgtcgg ttgtctttgt aataatgttc agaacaaagt acagctgaaa
    32941 aacgatggga aaaatcaagt ggtaaatcag tacgatgaca aatggcacac tcatgaaagt
    33001 ttagactaat accaaaacga tctaatatct gaatttcaaa aatatttgtc aaaatttcat
    33061 aatctaggcc ctcttccatc aaatcaagtg tttttttcaa aaacgtaaac aaatgcgaat
    33121 ctgattcatt atctgcaatc gcagcatcag ctaatgctaa gacataacta gcataggcta
    33181 atcgaaaaat atcattatta atataccgat aagtgttaac gttactatag tcaacaacat
    33241 aagacaagcc tgtatcattt aacttgaaaa taaaatcagc aatcgttagt ggttgaatga
    33301 ttgaggacat tttggaacga ctaatatgtt tcacgaaaaa catctgctta cctgctactt
    33361 cagtaaatat tttgactaat ttatcatctt ctcgataatt cctattaaaa agaacaatgc
    33421 ctagtgattc tgttagttgc atattacctc gtcgtatttt tctcttacct tttatcttag
    33481 tttacaataa actgttgtta tctttcttat tatacccaaa atcctttaga attgcatagt
    33541 tcatcccaca ataattaata ccacattacc cttacatttt attcaagtca aaaagcccga
    33601 gatctattat ctcaggcttc gttaagctta attgcccatc tcaaataaag gtgacaacgg
    33661 acgtttttca tgaatacgaa taatcgcttc tgcaaccaaa tcagcaattg aaatttgttc
    33721 aattttatca ataagacgtt cttttggcag ataaatagta tcaagaacaa ttagtttttc
    33781 gatagccgaa cgttgaatat tatcaagtgc tggtccagaa agaacgggat gcgtacatga
    33841 cgcatacaca gctgttgccc ccgcttcagc aagcgcatct gctgcatggc aaatagttcc
    33901 tgcggtatca atcatatcgt caatcaagat acatttcttg cccgaaacat ttccgataat
    33961 attcatcact tcactggtgt tcatcttatc cacactacga cgcttatcga taattgcaat
    34021 tggtgtttgg aggaattgtg ctaatttacg cgcacgagtc acaccaccat ggtcaggact
    34081 aacaacgaca acatcttcac ccactaaacc atgacgatca aaatagtctg caattaaagg
    34141 tgcacccatc aagtgatcaa ctggaatatc aaagaaccct tgaatttgag cagcatgtaa
    34201 atcaaccgtt aataagcgat ctacaccagc aacttctaac atattagcaa ctaattttga
    34261 agtaataggt tcacgagaac gcgctttacg gtcttggcgt gcgtagccgt agtaaggcat
    34321 cacaactgaa attttttcag cactagcacg ctttaaagca tcgaccataa tcaaaatttc
    34381 cattaaattg tcattgacag gtgagctagt tgattgcaaa ataaagacat gatgaccacg
    34441 aattgattct tcaatattta cttggatttc accatctgaa aactggcgaa ccgtagactt
    34501 tccaagttga atacccattg cagacgcaac tttttctgct aattccttgt ttgacgataa
    34561 agcaaacaat tttaaatcag aataagacat tttttcctcc aaagttttaa tcctatacca
    34621 ttttaacgct tttcaagtga attatcaaat gaaattgaaa aaccgttaaa gaatgtatta
    34681 aatatatctt ttatcgactt tatatacttc tcttatatta tacataagcg attggccaaa
    34741 caactctctt ataaattaac tatatcgtca atactctcag aactattcca caataggaat
    34801 aatcaaaaag gttagaacaa ctgttctaac ctaaataata tgttagtgtg gataaataaa
    34861 tgtaacacct gttggattaa accaaccacg gtgatcagca atgtactgtc taccactgta
    34921 gttagactcc atcacacgaa tacttgaggc actttgaacc tcaactacaa cggcgacatg
    34981 tccataacca ccatcgttcc aaacggcaat cgcacctacc atcggcgttg aaccagtacg
    35041 ataaccagct gcttgagcac tataagccca ttgaccacca tttccccaat tatttcctgc
    35101 ccaaggagct aaagatttag ctccccatgt gcattgtcca actggataag tattagaaga
    35161 atcatatgat gtttgtggtc ttgcagaagg agctgccgga gccgtgagtg cagctggttc
    35221 aatagcatta ctactttgcg ctgccggagt agcttgtggt gctggagtaa tagcagattt
    35281 tgctgcttca acagatgctg cttgttgtgc agcctgttct tgtgccttaa ctttagcagc
    35341 ctgttcttgt gctaaggctt cagcagcagc tttttctgca gcttcttttt gagctaccaa
    35401 attagcttta tcttcagtag cagatgctaa ttggagagct aaatttgcag ttgcagcttc
    35461 caaattagct tgttgagtac gtaatgtatt ttggttttct tcagccattg ccatattagc
    35521 ggcaatggta ttaatagctg tttggttagc agcttgcttt tcttcaaggg aaactttatc
    35581 agctttttgt tgttctaaca atttagcgtt agcagagaca gctctattaa ttgctactaa
    35641 acggtttaca acatcagaaa ttgatttaga attcaaaagt gcattaatgt aaccagaagt
    35701 ttcattgttt ttataagcac tacgagcttg attttttaat ttttcattac gagcaacaat
    35761 ttgacttgtt agagccttaa tttcttgctc aaatcgcttt gaaagtgcct caagttctgt
    35821 atttcttgcg gtcagtttat cttgttcaga ttgtagtgaa cttacttgag cctgtaacgc
    35881 tgaaacttga ttctgtgcag ctttttgctc tgtagtcaga tttgagataa tagaatcctg
    35941 cttagcaatc ttagtactca aatcctccgc tcctacagtt gtagctgctc cgagggtaac
    36001 accacttaca agaactgctg ataaaattct ttttttcata ataaaaaaac tactcctttt
    36061 cgataagaca tcttatattt taccaaaaaa aaaagtattt aatattacgc aattgttaca
    36121 gttatatgta ataaacaata aaaatatttt agggattatc ttataaaagt aaagcagcca
    36181 aaaagatata tctttcattt aaaatagaat acagtaaaat caatttaaat acataaaatt
    36241 acacaaaaag tttgaaaatt atatcttaag aacgctataa gtaatacaaa attgtttatc
    36301 ttcactcaga caccttatcc ttcttagaat gaatttttag ttacttatcc acaggttaat
    36361 aacttctttt cgcctaaaac attatccaca atagtgacat tttctattat cagtttatgc
    36421 ctttccattt tccaattaga atattagaca tcttttttga ccttatcatt attaatataa
    36481 gtatagtcag accttgtttt tttataagct aactatcgaa aactggtcat ctataaatct
    36541 tagtattcca tcactcaatc acaattcata aagactcgca aactttcaca acttttaatt
    36601 ctatactttc tatagtaggt aaatccacct caaagattat agagtctttt taaacatatg
    36661 taaaaagttc catatgacga tctataatga aaagcgacca aactatcatt ttagaaagac
    36721 tcatatagaa taatccgatt atagtataat ttcattagga atctaaaacc ttagcatcac
    36781 ggttttaaat tatgtaaatg ctgggaacgc aaaaagcatt cataatcatc tctttcatta
    36841 taccagacag gttagaaggc atgtcaaagt tattaccata agcatactca gtgcccacta
    36901 ctatgagatt actatgcttt ttctacaggc taaaattatc ctcgattttt tcatatcccc
    36961 caacgtctta gacaagctat aactcgcttt cgtatccgaa tcataaatac ttctgctata
    37021 aaacctatcg cgtatagaac tctcaaactt tactgaaaac tcatacagca tgattcacgg
    37081 aagctcatca ataatagctt tattgcccaa tttttcgtac gcccataact aacatctaaa
    37141 agaaaagaac aagattagca atatacttaa actcaactac tctaaggcca aattagaaac
    37201 agtcaacaac cttatcaaag ccatcaagtt aaacgtttta ctcctctaca gtagtcaaag
    37261 agcctatcat tttagttatc gaaataatga acgatttaaa tattctattt agttggtttt
    37321 gaagattaca aaaaaagacg ataaccgtct tctttcccct aatatgtttc atttaacata
    37381 ttaaccaaaa tatgtttaca aaacggagaa taagggattc gaacccttgc gccagttacc
    37441 cgacctaacg atttagcaaa ccgtcctctt cagcctcttg agtaattctc caaatatata
    37501 tgggcacgag tggactcgaa ccaccgacct cacgcttatc aggcgtgcgc tctaaccacc
    37561 tgagctacgc gccca
//
LOCUS       DAXMQE010000016        37107 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.016, whole genome shotgun sequence.
ACCESSION   DAXMQE010000016 DAXMQE010000000
VERSION     DAXMQE010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 37107)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37107)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37107
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.016"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            complement(110..1183)
                     /locus_tag="ACF4ZO_000959"
     CDS             complement(110..1183)
                     /locus_tag="ACF4ZO_000959"
                     /EC_number="2.7.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008887 - glycerate kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HFD5486513.1"
                     /translation="MKILVAIDSFKGSVTSSELNTSVAQALLSVDKQLVIETRAIADG
                     GEGSLAALSQTVAGRWYQVKTIDLLRRPIKVAYYRHAKQAFIESASIIGIDRITPNSV
                     TYAQATSYGLGLAVKDAIQKGATQIEIMLGGTGTSDGGKGFLESLNYDFMTGRSYLDT
                     LASPVTLLGLTDVTNPYHGPQGFAAVFGPQKGGSLSQIEETDQIASNFAKKVFYQTTI
                     DLQTIPGSGAAGGLGGAIVLLGGTLTSGFSRIAELLNLDNSLQSCDLVITGEGCLDTQ
                     SQSGKVPVAIARMAKKYQVPTIALCGSVKIETGLAAEDFLAVFSIQQQPISLEAAIDK
                     TTTLSNIKILAANLMLLIAQFNK"
     gene            1533..4511
                     /locus_tag="ACF4ZO_000960"
     CDS             1533..4511
                     /locus_tag="ACF4ZO_000960"
                     /EC_number="3.1.21.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009035 - type I site-specific
                     deoxyribonuclease activity [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HFD5486514.1"
                     /translation="MGNQTKTELELEKELIHLLETGESQWTYRKELKTEDALWDNFFK
                     ILAQNNTQYLNEEPLTASEKEQIKNQLNFVNYYEAAKWLAGENGIAKVQVQREDAKLG
                     AIRLEVVKADNVAGGTSVYEIANQVAFSGSRDRRGDVTLLINGLPMIQIELKSQNHQC
                     IEAFNQVKKYDKEGQFRGIFSTLQMFVVSNKTDTRYIAAAKENKLNPNFLTQWVDQNN
                     KPQKDLFAFAKEVLSIPLAHQMVMTYSVIDDDKKALILLRPYQIHAIEAVAEASRHRK
                     SGYIWHTTGSGKTLTSYKVARNILQIPAVEKSIFVIDRKDLDNQTTSAFQSYAQNDIF
                     DVDETEDTRQLIKNLESSDRRVVVTTIQKLNAMISQMESYDTPKFKKLKERLAHLNVV
                     FVVDECHRAVTPERQRHLTNTFRNSCWYGFTGTPIFVENKRAQLGDLAQTTEQQYGKC
                     LHQYTVKEAIHDKVVLGFQVEYKTTIPDMPEDSIPEEAYDHEEHMLAVLNSIINQSRK
                     KLGFNNGIGQTFEGLLTVKSIARAQAYYDLIQKVKAGETDLVISKKVKEKLPDFPKVA
                     ITYSITENDNASISRQDKMTKNLEDYNHLFGTNFTIDNLQGYNRDLNDRLARKKDKFK
                     DRHEQLDLVIVVDRLLTGFDAPCLSTIFIDRQPMKPQHIIQAFSRTNRIFESRKHYGQ
                     VVTFQTPLRFKEAVDKALSLYSNGGENDVLAPSWEEEKARFFEKVTVLKNIVPDPDAF
                     PTIESAQTAFLKQYAKAFQAFDKLFASVQVYSDFNETLLSEVGLSDEVIDTYKGTYQN
                     VIAEIRKRREDDEAIPEINIDYELESVQMDDINYHYILTLIQAFVDQEQEALQERLND
                     NPMDQYIQDLAKSNPAMADSLAELWQDIQKEPKAYEGKSIAYELDNLIGDKIQRAIKQ
                     FADQWKADPDKLAFVATNYHSANSTKQVGMSTLKESLDYQAYKEKQGDSAINKLKYKS
                     QFERELVQFIREQIQPLKGH"
     gene            4524..5732
                     /locus_tag="ACF4ZO_000961"
     CDS             4524..5732
                     /locus_tag="ACF4ZO_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HFD5486515.1"
                     /translation="MTKSKQPQYRFDSFEGEWEEKKLGEISNIVRGASPRPIQDPKWF
                     DSKSDIGWLRISDVTEQEGRITYLQQRISELGQEKTRVLKDPHLLLSIAATVGKPVIN
                     YVKTGVHDGFLVFLDPKFNREFMFQWLDMFRPYWNKYGQPGSQVNLNSEIVRNQVINL
                     PSLPEQEAIGELFQTVDQLLQLQDQKLATLKEQKQTFLRKMFPAQGQKVPEIRLQGFD
                     GEWEEKKLGEISRMFSGGTPNVGIPEYYNGNIPFIRSAEINSDQTELSITDKGLSNSS
                     AKLVEKNTLLYALYGATSGEVGLSRISGAINQAILAIIPEKKYSSLFIKNWLYKQKSS
                     IIEKYLQGGQGNLSGSIVKELTIHFPSLSEQEAIGNFFQTLDQQIAQSEEKLTELKAL
                     KQTLLNRLFV"
     gene            5745..7325
                     /locus_tag="ACF4ZO_000962"
     CDS             5745..7325
                     /locus_tag="ACF4ZO_000962"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0009007 - site-specific
                     DNA-methyltransferase (adenine-specific) activity
                     [Evidence IEA];
                     GO_process: GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HFD5486516.1"
                     /translation="MAEKTTSLRQALWHSADQLRGQMDANDYKNYLLGLIFYKHLSDK
                     LLLAVCDNLDQHFNTFTDAQKIFEDAYQDEDLKDDLISVVTGDLGYFIEPTLTFEKLI
                     QDVYHNTFQLESLAQGFSDIEQSGEDFENLFEDIDLYSKKLGSTPQKQNQTISNVMKT
                     LNEIDFEAVDGDTLGDAYEYLIGEFASESGKKAGEFYTPQAVSHLMTQIVFLGREDQK
                     GMTLYDPAMGSGSLLLNAKKYSNQSDTVSYYGQEINTSTYNLARMNMMLHGVAIENQH
                     LGNADTLDADWPTDEPTNFDGVLMNPPYSLKWSATAGFLTDPRFSSYGVLAPKSKADF
                     AFLLHGFYHLKNTGTMAIVLPHGVLFRGAAEGKIRQKLLEQGAIDTIIGLPSNIFYNT
                     SIPTTIIILKKNRTNKDVFFIDASKEFDKGKNQNTMTDSHIKKILDAYKSRDNSDKFS
                     YLASFDEIIENDYNLNIPRYVDTFEEVPVKPLPELAKQLSDIDQEIAKTNAKLDQLMK
                     QLVGTTKEAQDELDTFRN"
     gene            complement(7536..7736)
                     /locus_tag="ACF4ZO_000963"
     CDS             complement(7536..7736)
                     /locus_tag="ACF4ZO_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486517.1"
                     /translation="MPDMKSFLNLVKQKLFKPGLKKLVKLHNSQNVNICLYINDWNYF
                     MVRTMVFVEGSKVVLKISLNRV"
     gene            complement(7878..8483)
                     /locus_tag="ACF4ZO_000964"
     CDS             complement(7878..8483)
                     /locus_tag="ACF4ZO_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFD5486518.1"
                     /translation="MKILLIDDHRLFAKSIQLLFQQYDEVDVIDTITSHFNDVTIDLS
                     KYDIILLDINLTNISKENGLEIAKELIQSTPHLKVVMLTGYVKSIYRERAKKVGAYGF
                     VDKNIDPKQLISILKKVDSGKKYFEQIESQDYVESLTDQEIAILNLSKKGFSIKEIEE
                     TLQISRRTVFNHLTHIYSKLLVNNKQEAIYKAEQLGYFMDF"
     gene            complement(8464..10026)
                     /locus_tag="ACF4ZO_000965"
     CDS             complement(8464..10026)
                     /locus_tag="ACF4ZO_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFD5486519.1"
                     /translation="MIRIKNITKSKFFGTAIILLQQLIALLILIYHRKNLSLLFSEKV
                     ALVMTLIDTAFIWLATILRQKQGDIFKRIISIISLTIWQYLVSVLTRGTPLFLSSGLQ
                     IILLYCYTVEITNLILYGHKQFKDKLDKGLLIIIFVSITSLFVNRILFNFLFLMVFTI
                     LHLYPLLVIVLYYRSFRQQISVVRHSLILFSLLLLVILGSELYGEMLDVNQSFNNLGW
                     YLFPLIMSVIYYFKTIHDKLSFVTQRWLGDYKARIELLFLLLILCWMVLMKVLVKDFL
                     LFFIIVDASTLFCLVVISCIFYYLENSKQNFDYENRRLNYFMKSEENMRVEFSNYLHD
                     DVLQNIIAIKNLLSLENSNITHGFIVNELNDLVSGIRDEMDTYHPIVPANQTMKENIQ
                     SLFDDIVKSRKSNTLLYFNCSDNMVVPSPYGDIVYRFIKELINNAIKYGDGKDIRLSL
                     TIQSDIIIIEESNQVVEKVHSINYGRGLKSFQETLAAFDGDLELQMDTKQFTIRILLP
                     IDWKLCYEDFIN"
     gene            complement(10066..11973)
                     /locus_tag="ACF4ZO_000966"
     CDS             complement(10066..11973)
                     /locus_tag="ACF4ZO_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HFD5486520.1"
                     /translation="MIWSITKSNIKKNFSLYRIYFLATIGLLSIFIAFLNFISDKIIT
                     EKIGDSGQALVIANGSLVFLTVFLVIFLIYFNNFFVKKRSQELGVLAILGFSKRELTQ
                     LLTLENLVILVLSYLVSLLLGPTLYFLAVLVITHLLELTLEVQWFITANEIIESLGIL
                     VVVFLINVITNGLIISKQSLIEFVNFSRKAEKKIKIRKVRAIIAITALLLSYILCLAT
                     VFSSTRNMLLSIGMVPVSLLIIVLVVLGTVFTIRYGLAFVVSLLKGNKKRLYRPLSNI
                     IYPKFNYRIATKNKLLTVLGGLLTVTVSVAGMMVMLYAYSLNGIERLTPSAIEYNVKS
                     ENGQVNVTTILENDQVSLVDVDLLRLNTNPEVTITESGQTIPYFDIINYSDYKELMKA
                     QGRINSIEGSKSLPLLINYYPTEISLGKTFNLGNAYDVTVKQVSTHNVFSFSTSVTTL
                     VVSDKLYAKLSSCFPEKEMTTRTFNGNSIRSSEAFYNQFSMVPDVISSYSKEYTVKTA
                     NIATYIFITFLSILFIICTGSILYFTSLIEIMENKEEYGYLSKLGYSKKMIHRILRYE
                     TGILFLIPVFIGIVNGGMLLIYYKYLFMDTLVAGNIIMLSLLLCLLFFLIIYGTFYVL
                     TLRSVTSITKN"
     gene            complement(11975..12712)
                     /locus_tag="ACF4ZO_000967"
     CDS             complement(11975..12712)
                     /locus_tag="ACF4ZO_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000812013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD5486521.1"
                     /translation="MKQLVLKDVCKKYPNQLNYALDHINLIVEKGEFVAVMGRSGSGK
                     TTLLNVTSIIDKIDSGSIYCADKEISAFSDNEATNFRKNDIGFVFQDYMLLDSLTIRE
                     NISVALSLKNIDSSKIDDLINSYAKRFNLYEQLKKYPYQLSGGQRQRVSIIRAIIKEP
                     EIIFADEPTGALDLKSSEETMMILSEINKTEKVTILMVTHDVLSASYADRVVLLKDGK
                     LHLEIDKEDCGETFYDVISQALSDRGE"
     gene            complement(12709..13311)
                     /locus_tag="ACF4ZO_000968"
     CDS             complement(12709..13311)
                     /locus_tag="ACF4ZO_000968"
                     /inference="COORDINATES: protein motif:HMM:NF012235.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD5486522.1"
                     /translation="MGRGKRANLISFYQSPQNITFSKIDKTDFKNISAFVSQDSPIFD
                     GDVMYNISLGRESVSGEQVIETCKRVSIYDDIRSMPMKFHTPLFRDNPSLSGGQKQRI
                     SLARELVTTPRILVLDEPTSALDVKTERIIQKNVEALHCTRILVTHRLNTVEKADKIL
                     IMDNGKIIDYGNHHYLYKNNKDYCDLYDSYMNKYQEEEVK"
     gene            complement(13244..14869)
                     /locus_tag="ACF4ZO_000969"
     CDS             complement(13244..14869)
                     /locus_tag="ACF4ZO_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4135 domain-containing protein"
                     /protein_id="HFD5486523.1"
                     /translation="MIKRDELKLEYQNHQFYEYVNSIFDYDILDTSIRETSEVLRKKT
                     HKLFYSEFENQLFETIMFLSMKTLVLDINHFSKEIENKSEAYEQYMQQIREENGINHF
                     FDRYPYVLKQINKEVGLIEESYSLLFDRFLEDLSEIRSCFNISEPLSNVAFSLGDSHS
                     KKQTVVKIAFKEKSVYYKPKSYHSHSILLELTSLLKSSNIPSFSLPKSLVKADYCWQL
                     GVAYTSSNKDEVAKIYFKYGVLAAFSEIFSITDLHMENVIVSGGDLYLIDVETFFQRK
                     LNVQNQNFEGITVDTYQRIYETSLSNGLFPVQFEKNSAPNVSGISGKGGKRKKGKYEL
                     INKNRGDMKLVKVDYFQEDGFNIPTLNGKVVEPLDYANEIISGFRECYIFLLSQRSKI
                     KGIVEGFSELKSRALFRNTSDYGKFLQASTNPKYLFSEKKRKNLFSILYDAKHIEHFI
                     VNNEIKDLMNGDIPYFSMDTRGNVYNSVGTLIGNLGDTTSLFDSITILNDERLKFTCE
                     LLEIVLKKPIKHWEREKGKSYQFLSISSEHYLL"
     gene            complement(14953..15108)
                     /locus_tag="ACF4ZO_000970"
     CDS             complement(14953..15108)
                     /locus_tag="ACF4ZO_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA];
                     GO_process: GO:0042742 - defense response to bacterium
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type A2 lanthipeptide"
                     /protein_id="HFD5486524.1"
                     /translation="MSFMKNSKDILTNVIEEVSEKELMEVAGGKKGSGWFATITDDCP
                     NSVFVCC"
     gene            complement(15615..17021)
                     /gene="lacG"
                     /locus_tag="ACF4ZO_000971"
     CDS             complement(15615..17021)
                     /gene="lacG"
                     /locus_tag="ACF4ZO_000971"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033920 - 6-phospho-beta-galactosidase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HFD5486525.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLSEEFGVNGIRISIAWSRIFPTGKGEVNPKGVEYYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVNYAELCFKEFSEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLFKDSGYSGEIGVVHAL
                     PTKYPFDANNPDDVRAAELEDIIHNKFILDATYLGKYSDKTMEGVNHILEVNGGELDL
                     REEDFVALDAAKDLNDFLGINYYMSDWMQAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     KAPVDVPKTDWDWIIFPQGLYDQIMRVKADYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKKHLEVISDAISDGTNVKGYFMWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAYWYKKVAETQVIE"
     gene            complement(17094..18791)
                     /locus_tag="ACF4ZO_000972"
     CDS             complement(17094..18791)
                     /locus_tag="ACF4ZO_000972"
                     /EC_number="2.7.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002263057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0019197 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase complex [Evidence IEA];
                     GO_function: GO:0015155 - lactose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lactose-specific PTS transporter subunit EIIC"
                     /protein_id="HFD5486526.1"
                     /translation="MNGLIAQIEKGKPFFEKISRNIYLRAIRDGFIAGMPVILFSSIF
                     ILIAYVPNAWGFHWSKDIENLLMTPYNYSMGILGLFVAGTTAKALTDSMNRSLPSTNQ
                     INFISTMLAAIVGFLLMAANPAKDGGFLTGFMGTKGLLTAFIAAFITVNVYKVCVKNN
                     VTIRMPEEVPPNISQVFKDLIPFTLSVVLLYVIELIVHSTLGVNVAESIGKLLAPLFQ
                     AADGYVGITIIFGAFALFWFVGIHGPSIVEPAIAAITYANAETNLQLLQAGEHADKIL
                     TSGTQMFIVTMGGTGATLVVPFMFMWLTKSKRNKAIGRASVVPTFFGVNEPILFGAPL
                     VLNPIFFIPFILAPIVNVWIFKFFIDTLGMNSFTANLPWTTPAPLGLILGTNFQVLAF
                     ILAALLIVVDVIIYYPFLKVYDEQILAEEAAGTNSSDVLKEKVAANFDTKKADAILEK
                     SAAKETKEITDQTNVLVLCAGGGTSGLLANALNKAAKEYGAPVTAAAGSYGAHREILP
                     QYQLVILAPQVASNYEDMKVETDKLDIKLAKTEGAQYIKLTRDGQGALDFVKEQMEE"
     gene            complement(18791..19108)
                     /locus_tag="ACF4ZO_000973"
     CDS             complement(18791..19108)
                     /locus_tag="ACF4ZO_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HFD5486527.1"
                     /translation="MNREETTLLGFEIVAYAGDARSKFLEALKAAQEGDYAKAEELIA
                     AGSDCLNDAHNAQTSLLQKEAAGDDLAYSVTLMHGQDHLMTTILLQDLMKHMIELYKR
                     GAK"
     gene            complement(19132..20115)
                     /gene="lacD"
                     /locus_tag="ACF4ZO_000974"
     CDS             complement(19132..20115)
                     /gene="lacD"
                     /locus_tag="ACF4ZO_000974"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009025 - tagatose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HFD5486528.1"
                     /translation="MTITLTENKRKSMEKLSIDGVISALAFDQRGALKRMMAQHQTKE
                     PTVEQIEELKSLVSEELTPFASSILLDPEYGLPASRVRSEEAGLLLAYEKTGYDATTT
                     SRLPDCLDVWSAKRIKEAGAEAVKFLLYYDIDGDQDVNEQKKAYIERIGSECRAEDIP
                     FYLEILTYDEKIADNASPEFAKVKAHKVNEAMKVFSKERFGVDVLKVEVPVNMKFVEG
                     FADGEILFTKEEAAQAFRDQEASTDLPYIYLSAGVSAKLFQDTLVFAAESGAKFNGVL
                     CGRATWAGSVKVYIEEGPQAAREWLRTEGFKNIDELNKVLDKTASPWTEKM"
     gene            complement(20119..21048)
                     /locus_tag="ACF4ZO_000975"
     CDS             complement(20119..21048)
                     /locus_tag="ACF4ZO_000975"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018379688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009024 - tagatose-6-phosphate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HFD5486529.1"
                     /translation="MILTVTLNPAIDVSYPLDELKCDTVNRVVDVTKTPGGKGLNVCR
                     VLNDFGETVKATGCIGGESGDFIINHLPDSILSRFYKISGDTRTCIAILHEGNQTEIL
                     EKGPLLSVNEIDGFTHHFKYLLNDVDVVTLSDSLPAGMPDDYYQKLIGIANLNGKKTV
                     LDCSGNALEAVLKGDSKPTVIKPNLEELSQLLGKEMTKDFDALKEVLQDKLFDGIEWI
                     IVSLGADGVFAKHKDTFYKVDIPKIKIVSAVGSGDSTVAGIASGLANDEDDRALLTKA
                     NVLGMLNAQEKTTGHVNMANYDKLYQSIKVKEV"
     gene            complement(21094..21609)
                     /gene="lacB"
                     /locus_tag="ACF4ZO_000976"
     CDS             complement(21094..21609)
                     /gene="lacB"
                     /locus_tag="ACF4ZO_000976"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HFD5486530.1"
                     /translation="MKIAVGCDHIVTYEKIAVVDYLKSQGHKVIDCGTYDNVRTHYPI
                     FGKKVGEAVASGKAELGVVICGTGVGITNAVNKVPGIRAALVRDMTSAIYSKEELNAN
                     VIGFGGKIIGGLLMNDIIDAFLAAEYKPTEENKKWIEKMDSLQHTNQDQNNPHFFDEF
                     LEKWDRGEYHD"
     gene            complement(21644..22072)
                     /gene="lacA"
                     /locus_tag="ACF4ZO_000977"
     CDS             complement(21644..22072)
                     /gene="lacA"
                     /locus_tag="ACF4ZO_000977"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HFD5486531.1"
                     /translation="MAIIIGADKAGQELKEVIKDYLKEGKYEVVDVSENEVRDFVDTT
                     LAVAKEVNASEDNLGIVIDAYGVGSFMVATKIKGMVAAEVSDERSAYMTRGHNNARII
                     TLGSEISAPGIAKNIIKGFVEGKYDGGRHQVRVDMLNKMC"
     gene            22517..23290
                     /locus_tag="ACF4ZO_000978"
     CDS             22517..23290
                     /locus_tag="ACF4ZO_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004270277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFD5486532.1"
                     /translation="MKKKERHEKILDILKVDGFIKVKDIIDEMNISDMTARRDLDTLA
                     DKGLLIRTHGGAQYLDYSSAKDEGHEKTHTEKKVLQTTEKKQIAQRAKNIIKDGETVF
                     IGPGTTLEHLAVELKNRNIRVITNSLPVFLILHPCTTIDLILIGGECREITGAFVGAI
                     AINNLETLTFSKAFVSANAVYNNSIATYSDLEGEVQRVALNNAVEKILLVDSTKFESY
                     DFYNFYQLDQVDLIVTDKNVTTNIIEKYKKFSKIIIADK"
     gene            23940..24227
                     /locus_tag="ACF4ZO_000979"
     CDS             23940..24227
                     /locus_tag="ACF4ZO_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-damage-inducible protein J"
                     /protein_id="HFD5486533.1"
                     /translation="MTTVKKNRAVTFQANKELVSEAMTVLNKKNLTLSSALRLFLQNV
                     VVTNEVDLLTEEELEKEKLFKQFQAEINKNIEDVRQGKFYTSEEVRAELGL"
     gene            24217..24552
                     /locus_tag="ACF4ZO_000980"
     CDS             24217..24552
                     /locus_tag="ACF4ZO_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HFD5486534.1"
                     /translation="MDYKKYQIIYAPDVLEKLKEIRDYISQNYSSTSGQRKMEQIISD
                     IEKLEVFPEVGFDADEKYGSKIIHYHSTKGYTLSKDYIVLYHIEGEENRVVIDYLLPT
                     QSDYIKLFK"
     gene            24650..25688
                     /locus_tag="ACF4ZO_000981"
                     /pseudo
     CDS             24650..25688
                     /locus_tag="ACF4ZO_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003070648.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
     gene            complement(25820..26212)
                     /gene="rpsI"
                     /locus_tag="ACF4ZO_000982"
     CDS             complement(25820..26212)
                     /gene="rpsI"
                     /locus_tag="ACF4ZO_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HFD5486535.1"
                     /translation="MAQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLIINQPFAVTSTEGSYDVFVNVVGGGYGGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(26233..26679)
                     /gene="rplM"
                     /locus_tag="ACF4ZO_000983"
     CDS             complement(26233..26679)
                     /gene="rplM"
                     /locus_tag="ACF4ZO_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HFD5486536.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKIKLTGKKATDKVYYTHSMYPGGLKSITAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGGEHTHAAQQPEVLDISGLI"
     gene            complement(26897..27103)
                     /locus_tag="ACF4ZO_000984"
     CDS             complement(26897..27103)
                     /locus_tag="ACF4ZO_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFD5486537.1"
                     /translation="MKNLKLKAARAGKDLSQQALADLVGVSRQTIAAVEKGDYNPTIN
                     LCIAICRVLDKTLDDLFWEADDSR"
     gene            complement(27100..27798)
                     /locus_tag="ACF4ZO_000985"
     CDS             complement(27100..27798)
                     /locus_tag="ACF4ZO_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486538.1"
                     /translation="MFDSKQNLAKSQWMFIIIIAVMDLVVLVATLLAKTSFQRYLVGG
                     VAVILTSFLILLVWGLKTAKKLQTRLDSKEVLDSKVRDDQKLPKYDERQKQILLKGYT
                     IGFWFMIVVIWLSLFISRFTEGLVSASFLFTLALWGGLAVQTTYCNLNGASSFVDRRF
                     GKQGILMGMIATGMSLVTIGLAVREMMAGQLKMGSFFKAGGSGSLMVLGITLLSMGAS
                     IFYRHYLDAKEADE"
     gene            complement(27934..28794)
                     /locus_tag="ACF4ZO_000986"
     CDS             complement(27934..28794)
                     /locus_tag="ACF4ZO_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HFD5486539.1"
                     /translation="MTFTIMTDSTADLNQTWAEDHDIVLIGLTILCDGEVYETVGPNR
                     ISSDYLLKKMKAGSHPQTSQINVGEFEKVFREHARNNKALLYLAFSSVLSGTYQSALM
                     ARDLVREDYPDAVIEIVDTLAAAGGEGYLTILAAEARDSGKNLLETKDIVEAVIPRLR
                     TYFLVDDLFHLMRGGRLSKGSAFLGSLASIKPLLWIDEEGKLVPIAKIRGRQKAIKEM
                     VAQVEKDIADSTVIVSYTSDQGSAEKLREELLAHENISDVLMMPLGPVISAHVGPNTL
                     AVFVIGQNSR"
     gene            complement(28891..29409)
                     /locus_tag="ACF4ZO_000987"
     CDS             complement(28891..29409)
                     /locus_tag="ACF4ZO_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HFD5486540.1"
                     /translation="MKKRILLVDGYNMIAFWQSTRQLFKTNQLDQARNTLLTKLNHYA
                     HFENINIICVFDAQYVPGLRQRYDQYYISVVFTEEDETADSYIERMAAELNTAIHMVE
                     VATSDLNEQWTIFSQGALRVTARELEQRVHTVKADLDKMSRDIDLKTPKLRPFDQGQL
                     SQLKDFMSQLDR"
     gene            complement(29413..30159)
                     /gene="rlmB"
                     /locus_tag="ACF4ZO_000988"
     CDS             complement(29413..30159)
                     /gene="rlmB"
                     /locus_tag="ACF4ZO_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HFD5486541.1"
                     /translation="MEDKDTIETNDIVYGVHAVTESLQANTGNKLYIQEDLRGKKVDN
                     IKSLATQKKVAISWTPKKTLSQMTDGAVHQGFVLRVSAFAYTDVDEILEIAEQEANPL
                     ILILDGLTDPHNLGSILRTADATNVCGVIIPKHRSVGVTPVVSKTSTGAVEHIPIARV
                     TNLSQILDKLKARGFWIFGTDMNGTPSDCWNTNGKLALVIGNEGKGISTNIKKQVDEM
                     ITIPMNGHVQSLNASVAAAILMYEVFRNRR"
     gene            complement(30206..31003)
                     /locus_tag="ACF4ZO_000989"
     CDS             complement(30206..31003)
                     /locus_tag="ACF4ZO_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486542.1"
                     /translation="MTTMQKTVSLLSLALLIGLLGTSGKAISVYAQDQHTDNVIAEST
                     ISQVSVEASMRGTEPYIDATVTTDQPVRQPTQATITLKDASDNTINSWVYTMAAQQRR
                     FTAWFDLTGQKSGDYHVTVTVHTQEKAVTGQSGTVHFDQNKARKTPTNMQQKDTSKAT
                     TNSVDVDTKAQANQSANQEIDSTSNPFKSATNHRSTSLKRSTKNEKLTPTASNSQKNG
                     SNKTKMLVDKEEVKPTSKRGFPWVLSGLVVSLAAGLFIAIQKVSRRK"
     gene            complement(31199..31612)
                     /locus_tag="ACF4ZO_000990"
     CDS             complement(31199..31612)
                     /locus_tag="ACF4ZO_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HFD5486543.1"
                     /translation="MTNPVDVNLINGIALAFEGDAVYSYYVRRHLIFQGKTKPSQLHR
                     LATRYVSAKAQANLIQAMLEAQLLTEKEEDIYKRGRNTNSHTKAKNADIITYRMSTGF
                     EAIMGYLDMMGQKERLEELIRWCIEYVEKQQLISS"
     gene            complement(31605..32948)
                     /gene="cysS"
                     /locus_tag="ACF4ZO_000991"
     CDS             complement(31605..32948)
                     /gene="cysS"
                     /locus_tag="ACF4ZO_000991"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000591125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004817 - cysteine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006423 - cysteinyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HFD5486544.1"
                     /translation="MIKIYDTMTRSLRKFVPLTENTVNMYVCGPTVYNYIHIGNARSA
                     VAFDTIRRYFEYTGYQVNYISNFTDVDDKIIKAATQAGVSPKELSDRFIAAFIEDTKA
                     LGVKPATQNPRVMDYIAEIISFVESLIEKDFAYEADGDVYFRVEKSEHYAKLANKTLS
                     ELEVGASGRTDAETALKENPLDFALWKSAKAGEVSWDSPWGFGRPGWHIECSVMATEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKTFANYWMHNGFVTVDNEKMSKSLGNF
                     VTVHDMLQTVDGQVLRFFLATQQYRKPINFTEKAIHDAEINLKYLKNTLQQPLTETAD
                     EQELKQFVIAFQDAMDDDFNTANGITVVFDMAKWINSGSYTEPVKSAFEKMLAVFGIV
                     FEEEVLEVDIEALIAKRQEARANRDFATADAIRDQLAAQGIKLLDTKDGVRWLRD"
     gene            complement(32976..33206)
                     /locus_tag="ACF4ZO_000992"
     CDS             complement(32976..33206)
                     /locus_tag="ACF4ZO_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486545.1"
                     /translation="MNKIRVGLYVIMSSSILVSSITLVASLIFLLRQDMVKAIIYFIL
                     TLFWLIGLVINIKLLKRWNSISEKDLGYQDDN"
     gene            complement(33685..34266)
                     /gene="cysE"
                     /locus_tag="ACF4ZO_000993"
     CDS             complement(33685..34266)
                     /gene="cysE"
                     /locus_tag="ACF4ZO_000993"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0009001 - serine O-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HFD5486546.1"
                     /translation="MGWWKESIAIVKALDPAARNSLEVILTYPGIKALAAHRLSHFLW
                     RHHFKLLARMHSQFWRFWTQIEIHPGAQIAPGVFIDHGAGLVIGETAIVEKGVMLYHG
                     VTLGGTGKDCGKRHPTIRQGALISAHAQVIGPIDIGANAKVGAAAVVLSDVPEDVTVV
                     GVPAKIVRVHGQKDNRQIQSLQKQREVSYQLSK"
     gene            complement(34275..35027)
                     /locus_tag="ACF4ZO_000994"
     CDS             complement(34275..35027)
                     /locus_tag="ACF4ZO_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SseB family protein"
                     /protein_id="HFD5486547.1"
                     /translation="MTKSNELDIRLRAFINAPDNFLDSLALVNAFHNFPVWAAKEPYV
                     IEVEGVKVTPVFTDKEDMARFKEEQKSAQSQYWLERSALAVLEEVITSGAAGLVFNLK
                     KKGDFGNSTIFKSSDMIQFMNHYTTVLNTLMSDDNVAADTMEKVYLVPAFVYPKDNNH
                     YDRLFPTMSTPEGKSYVPAFSNLQSFAKWYNQDDFGGLFRKAEGVILTWTIDDIYQPR
                     NGENELDETFGVAINPFDDQQILVDWSELDKS"
     gene            complement(35020..>37107)
                     /gene="pnp"
                     /locus_tag="ACF4ZO_000995"
     CDS             complement(35020..>37107)
                     /gene="pnp"
                     /locus_tag="ACF4ZO_000995"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018366801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004654 - polyribonucleotide
                     nucleotidyltransferase activity [Evidence IEA];
                     GO_process: GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HFD5486548.1"
                     /translation="VVEVGQVAKQANGATVVRYGESTVLTAAVMSKKMATGDFFPLQV
                     NYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFAEGFRNEVQVTNTVLS
                     YDENASAPMAAMFGSSLALSISDIPFNGPIAGVQVGYIDGEFIINPDKEQMEASLLEL
                     TVAGSKEAINMVESGAKELSEDIMLEALLKGHQAIQELIAFQEQIVAVVGKEKAEVEL
                     LQVDADLQADIVAKYNAQLQKAVQVEEKKAREAATEAVKEMVKAEYEERYAEDENLAT
                     IMRDVAEILEQMEHAEVRRLITEDKIRPDGRKIDEIRPLDAVVDFLPKVHGSGLFTRG
                     QTQALSILTLAPMGETQIIDGLAPEYKKRFLHHYNFPQYSVGETGRYGAAGRREIGHG
                     ALGERALEQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGTLALMAGGVPIKAPVA
                     GIAMGLISDGTNYTVLTDIQGLEDHFGDMDFKVAGTREGITALQMDIKIAGITPQILE
                     EALAQAKKARFEILDVIEATIAEPRPELAPTAPKIDTIKIDVDKIKVVIGKGGETIDK
                     IIAETGVKIDIDDEGNVSIYSSDQAAINRTKEIIAGLVREAKVGEVYHAKVVRIEKFG
                     AFVNLFDKTDALVHISEIAWTRTTNVSDVLEVGEDVDVKVIKIDEKGRVDASMKALIP
                     RPPKPEKKEEKHD"
BASE COUNT        11778 a         7338 c         6224 g        11767 t
ORIGIN      
        1 aaatgtttct gtttttcata ctatgctaat gagttagctc gtgcgtctcc ttcttcatag
       61 gttactttta accgccaaat gaatgctaca caatcgaaaa tagatgagtt tacttattaa
      121 actgagctat caatagcata aggttagctg ctaatatttt gatattagaa agtgttgttg
      181 ttttatctat cgctgcttct aaggaaattg gctgctgttg tattgaaaaa acagccaaaa
      241 agtcttctgc tgctagtcct gtctcaatct ttacagaacc gcatagagca atcgttggaa
      301 cttgatattt tttagccatt cttgcaatcg caacaggtac cttgccagat tgtgattgtg
      361 tatccaggca tccttctcca gtaataacta aatcacaaga ctgaagggaa ttatccagat
      421 ttagtagctc tgcaatcctg ctaaaaccac tagttaaggt gcctcctaat aggacaatgg
      481 cacctcctaa tcctccagct gctccacttc ctggtattgt ctgtaaatca atggttgttt
      541 ggtaaaaaac ttttttagca aagttacttg caatttgatc tgtttcttca atttgactaa
      601 ggctcccacc tttttgaggg ccaaagaccg cagcaaatcc ttgagggcca tgatatggat
      661 tggttacatc agtcagacct aatagcgtaa caggtgatgc taaagtatca agataagatc
      721 ttcctgtcat gaaatcatag tttaaacttt ctaaaaaccc tttgccacca tcagaagtgc
      781 ctgttcctcc tagcatgatt tcgatttgag tagctccttt ttgaatggca tctttaactg
      841 ccaaacccaa accgtaggaa gtggcttgtg cataggttac tgaattgggg gttatcctat
      901 caataccaat aatactcgca gattcaataa aagcttgctt tgcgtgacga taataagcga
      961 ctttaatcgg gcgtcttaat agatcaatgg tttttacttg ataccacctc cccgccacgg
     1021 tttgtgagag ggctgctaaa cttccttctc ctccatcagc gatagctctt gtttcaataa
     1081 ctaactgctt atcgacagaa agaagggctt gagctacact agtgttaagt tctgaagacg
     1141 ttaccgatcc cttaaaagaa tctatggcta ccaaaatttt catatcttca ataaattcct
     1201 tttctgtata ttgtagcaga ttatcgtcct ttaaaaccct attaatagtc aagctagatc
     1261 tgtcttaagt tttttatcta ttttgagaac tcgacctttt tactagtgtt gtcttattac
     1321 tttcttcacc ttaaattatt gtcaagcaaa ctcaaaaata caagaacttt ctcgattgca
     1381 tttacatagt catagctttg tttagttgct aggatcttaa gcattcaact aatcaaaaaa
     1441 agactgtttg gaaggtttca atagctttgc cattctaaaa aggatccgcc aatgatataa
     1501 tactactata tcatgtcgaa tggggattaa aaatgggaaa tcaaactaaa acggaacttg
     1561 aacttgaaaa agagttgatc catctcttag aaacaggtga aagtcaatgg acatatcgta
     1621 aagaattaaa aactgaagat gctttatggg ataatttctt taagatctta gcgcaaaata
     1681 acacgcaata tctgaatgag gagcctttaa cagctagtga aaaagagcag attaagaatc
     1741 aacttaactt tgtcaattac tatgaagcgg ctaaatggtt agctggtgaa aacggcattg
     1801 ctaaagtaca agtgcaacgc gaagatgcaa aactaggagc gattcgttta gaagtcgtta
     1861 aagcagacaa tgtggctggt ggaacttctg tttatgagat tgccaatcaa gttgctttct
     1921 ctggttctcg tgatagacga ggtgatgtga cacttctcat caatggctta cctatgatcc
     1981 aaattgaatt aaaatctcag aatcatcaat gcattgaagc ttttaaccaa gtcaaaaagt
     2041 atgataaaga aggccagttt agaggtatct tttcaacctt acaaatgttt gtggtctcaa
     2101 ataaaacaga tacaaggtat atcgctgcag ctaaagaaaa taaattaaat cctaacttct
     2161 tgacccaatg ggtagatcaa aacaacaaac cacaaaaaga tctctttgct tttgccaaag
     2221 aagtcctatc tatccctctt gctcaccaaa tggtcatgac ttactctgtc attgatgatg
     2281 ataaaaaagc actaattctc cttcgtcctt atcagattca tgcaatcgaa gccgtcgctg
     2341 aagcgagtcg tcaccgcaag tctggctata tctggcacac aacaggttct ggaaaaacct
     2401 taacttccta taaagtggct cgcaatatcc ttcaaatacc ggccgttgaa aaatccatct
     2461 ttgtcattga ccgaaaggat ttagataatc agaccacttc tgcttttcaa tcttatgcgc
     2521 aaaatgatat ctttgatgtc gatgagacag aagatacgag acaactcatc aaaaatttag
     2581 aatccagtga tcgtcgtgtt gtggtcacca ccattcaaaa actcaatgct atgatcagtc
     2641 agatggaaag ttatgacact ccaaaattca agaaactaaa agagcgtctt gcacacctaa
     2701 atgtcgtctt tgttgtagac gaatgccacc gtgctgtcac gccagaacgg cagcgtcatc
     2761 tcacgaatac ttttcgaaac agttgctggt atggctttac aggtactcct atctttgtgg
     2821 aaaataagcg tgctcaatta ggtgatttag cccaaacaac ggaacagcaa tacggcaaat
     2881 gtctccatca atacactgtc aaagaagcca ttcacgataa agtggttcta ggcttccaag
     2941 ttgagtataa gacaaccatt cctgatatgc ctgaagacag tattcctgaa gaagcttatg
     3001 atcatgaaga acatatgtta gctgtcttaa atagtatcat taatcaatca cgtaagaagc
     3061 ttggctttaa taatgggatt ggtcagacat tcgaaggctt attaaccgtt aagagtattg
     3121 ctcgtgccca agcctattat gatctgattc agaaagttaa agctggtgaa acggatttag
     3181 tcatttctaa gaaggtcaaa gaaaaactac cagactttcc aaaggtagct attacttatt
     3241 ctatcactga aaatgacaat gcgtctatca gccgacaaga taaaatgacc aaaaatctag
     3301 aagactataa tcacctcttt ggcactaact ttaccatcga taacttacaa ggctataaca
     3361 gagatttaaa tgatcgctta gcccgtaaaa aagataaatt caaagaccgt catgaacaat
     3421 tagacctcgt gattgtggtt gaccgtctct taacaggttt tgatgcgcct tgtttatcaa
     3481 cgatctttat tgatcgccag cctatgaaac ctcagcacat tattcaagct ttctcacgaa
     3541 ccaaccgtat ctttgaaagt agaaaacatt acggtcaggt tgtgactttc caaacaccac
     3601 ttcgttttaa agaagctgtc gacaaagcgc ttagcctcta ctctaatggg ggtgaaaacg
     3661 acgttttggc cccttcttgg gaagaagaaa aagcaagatt ctttgaaaaa gtaacagtat
     3721 taaaaaatat agttcctgat ccagacgctt tcccaactat tgagagcgca cagacagctt
     3781 ttctcaaaca atacgccaaa gcctttcaag catttgataa actctttgca tctgtacaag
     3841 tctatagtga ctttaatgaa acactgttga gtgaggttgg gttatcagat gaagtgattg
     3901 atacttataa aggcacttac caaaatgtca ttgcagaaat acgaaaacga agagaagatg
     3961 acgaagccat cccagagatc aatatcgact atgagctaga aagtgttcag atggatgata
     4021 tcaactatca ctatatcttg accttaattc aagcctttgt cgatcaagaa caagaagctc
     4081 ttcaagaaag gctcaatgac aatcccatgg atcaatacat ccaagatttg gcaaaatcaa
     4141 accctgctat ggctgactca ctagctgagt tatggcaaga tatccaaaaa gaacccaaag
     4201 cctatgaagg gaaaagcatt gcttatgagt tggataacct cattggtgat aagatccaaa
     4261 gggctatcaa acaatttgcg gaccaatgga aggcagatcc tgacaaatta gcctttgtgg
     4321 cgactaatta tcatagtgct aactctacca aacaagtggg catgtcaacc ttaaaagaat
     4381 ccctagacta ccaagcctat aaagaaaaac aaggtgattc tgccataaat aaactcaaat
     4441 acaagagcca atttgaacgg gagttagttc aattcattag agagcaaatc caacccttaa
     4501 aagggcacta ggaaaggaaa gagatgacaa aatctaaaca gcctcaatat cgctttgaca
     4561 gttttgaagg ggagtgggaa gagaaaaagc tgggagaaat ttctaatata gttcgtggtg
     4621 ccagtcctag accgatacaa gatccaaaat ggtttgattc caaaagtgat ataggttggt
     4681 taagaatttc tgatgttact gaacaagaag gtcgtataac ttatttacaa caaagaatat
     4741 ctgagcttgg tcaagaaaag actagagtat taaaggatcc acatttacta ttaagtattg
     4801 cagctacagt aggtaaacca gttatcaatt atgttaaaac tggagtacac gatggatttc
     4861 ttgtgttttt agatcctaaa ttcaaccgtg aatttatgtt tcagtggtta gatatgttca
     4921 gaccatattg gaataaatat ggtcaaccag gaagccaagt gaatctgaat tctgaaatag
     4981 ttcgaaatca agttatcaat ctcccctctc tccctgaaca agaagccatt ggcgagctct
     5041 tccaaacggt tgatcaactg cttcagttac aggatcaaaa gctagcaact ctaaaagaac
     5101 aaaagcaaac cttcctcaga aagatgttcc cagcccaagg acaaaaagtc cctgaaatcc
     5161 gtttacaagg ttttgatggt gagtgggaag agaagaaatt gggggagata tctcggatgt
     5221 tttcaggtgg cactcctaac gtaggtatcc ctgaatacta taatggtaat attcctttca
     5281 ttagatctgc tgagatcaac agtgatcaaa cagaattatc tatcacagac aaaggtctat
     5341 caaattcatc agcaaaatta gtggaaaaaa atacattatt atacgctctc tacggtgcaa
     5401 ctagtggaga ggttggactt tcaagaataa gtggagctat taatcaagca attttagcca
     5461 ttattcctga gaaaaaatat tcttctcttt ttataaaaaa ttggttatat aaacaaaaat
     5521 cctcaattat tgagaaatat ttacaaggtg gccaaggaaa tttatctggt tctattgtta
     5581 aagaattaac tattcatttc ccttccctct cagaacaaga agccattggt aatttcttcc
     5641 aaactttaga ccaacaaatt gctcaatctg aagaaaaact aacagaactt aaagcactca
     5701 aacaaacatt actcaatcgt ttattcgtat aagaaaggac tcacatggca gagaaaacaa
     5761 cttcactccg gcaagcacta tggcattcgg ccgaccaatt acgtggccaa atggatgcca
     5821 atgactataa aaactatctt cttggactta ttttttacaa acacttatct gataaattac
     5881 tcttggctgt ttgtgataat ttagatcaac actttaatac ctttacagat gctcaaaaaa
     5941 tctttgaaga tgcttatcaa gatgaagacc taaaagatga cctcatttct gttgttactg
     6001 gtgatttagg ttactttatc gaaccgacac tgacctttga aaaactcatc caagatgttt
     6061 atcacaatac tttccaatta gaatcattag ctcaaggttt tagcgatatt gaacaaagtg
     6121 gtgaagactt tgaaaactta tttgaagata ttgacctcta ctctaaaaaa ttaggctcta
     6181 ctcctcaaaa acaaaatcaa accatttcta atgtcatgaa aacattaaat gaaattgact
     6241 ttgaggcagt agatggggat actttaggtg atgcttatga gtacttgatt ggtgaatttg
     6301 ccagtgaatc aggaaaaaaa gcaggtgagt tctatacccc acaagctgtc tctcacttaa
     6361 tgactcagat tgtcttttta ggtcgtgaag atcaaaaagg aatgaccctc tatgaccctg
     6421 ctatgggatc tggatcactc cttttaaatg ctaagaaata tagtaaccaa tccgataccg
     6481 tttcttacta tggtcaagaa atcaatactt ctacttataa cttggctcgt atgaacatga
     6541 tgcttcatgg cgttgccatc gaaaaccaac acttaggtaa cgctgatacc ttggatgcag
     6601 actggccaac agatgaacca accaactttg atggggtgtt gatgaaccca ccttattctt
     6661 tgaaatggtc agcgactgct ggtttcttaa cggatccacg gttttcaagt tatggtgtat
     6721 tagcaccaaa atcaaaagct gactttgcct ttttacttca tggtttctat catttaaaaa
     6781 atacaggaac tatggcaatt gtcttaccac atggtgttct tttccgtgga gctgcagaag
     6841 gcaagattcg ccaaaaacta ctcgaacaag gggctattga tactatcatc ggactcccat
     6901 caaatatctt ttataataca agcatcccta cgactattat catattaaag aagaacagaa
     6961 ccaacaaaga tgtcttcttt atcgatgcct caaaagagtt tgataagggc aaaaatcaaa
     7021 acacaatgac agatagccat atcaaaaaga tccttgatgc ttataagagt cgtgataatt
     7081 ctgataagtt ttcgtactta gcctcatttg atgaaatcat tgaaaatgac tataacttaa
     7141 atatcccacg ctatgttgat acctttgagg aagtcccagt taaaccactg ccagaattag
     7201 ctaaacagct cagtgacatt gatcaagaaa ttgccaaaac aaatgccaaa ctagatcaac
     7261 tcatgaaaca actagtcgga acaaccaaag aagcacaaga cgaattggat acttttagaa
     7321 actaaaagac aaaaaaacac cacagtagat gattactact gtggcgtttt atttaaaatt
     7381 gagtagtgaa cctttattga gtacttatca tacaagattc tccttcttca cctataaatc
     7441 aaaatagaat catctcatct aactttgtcc gttttctttg ttttatttaa aatagttatt
     7501 tgaagttaca atgatttctc aaacgtttag aaagcttaaa cacggttaag agaaattttc
     7561 aggacaactt ttgatccttc cacaaaaacc atggtgcgaa ccataaagta gttccaatcg
     7621 ttgatatata agcatatatt aacgttctgg gagttgtgaa gctttacgag tttttttaga
     7681 cctggtttaa acaacttttg tttgactaaa tttaaaaagc ttttcatatc aggcatttcc
     7741 ctacttttta taaaagcgtt atctcaatca atttcaatca aaaagaactc aaaaacaatg
     7801 agtttaaatc tgggtattta acaggaaatc cctagcaacg acacaagtaa aacttatgtc
     7861 gtttgattat ctgcaactca gaaatccata aaatacccta attgttcggc tttgtagata
     7921 gcctcttgct tattatttac caaaagcttt gagtagatgt gggtcaaatg attaaatact
     7981 gttctcctac taatttgtaa cgtttcctct atttctttta tagagaatcc tttcttactc
     8041 aaatttaaga tagctatttc ctggtcagtt aaagattcaa cataatcctg agattcgatt
     8101 tgttcaaaat acttttttcc agaatccact ttttttaaga tagaaatgag ttgtttaggg
     8161 tctatatttt tatctacaaa accgtatgct cctacttttt ttgccctctc tctatagatt
     8221 gatttaacat atcctgtcaa cataacaact ttcaaatgag gagtagactg tatgagttct
     8281 tttgctatct ccaatccatt ttctttagaa atatttgtta aattaatatc aagcaatata
     8341 atatcgtact tagacaaatc aatcgtcaca tcgttaaaat gagaagtaat cgtatctatg
     8401 acatctactt catcatactg ttggaataac agttggatac tctttgcaaa tagtctgtgg
     8461 tcatcaatta ataaaatctt cataacacaa tttccaatct atgggaagta atattctgat
     8521 ggtaaattgt ttagtatcca tttgtagttc tagatctcca tcaaaagctg ctagtgtttc
     8581 ttgaaatgat ttcaatcctc tgccataatt tatagagtgt actttttcca ctacttgatt
     8641 gctctcctca atgataataa tatcagattg aatcgttaaa gataaacgaa tgtcttttcc
     8701 atctccatat tttatagcat tgtttattag ctcttttata aacctataaa caatatctcc
     8761 atatggggat ggcactacca tattatctga acagttaaaa tacaataagg tattactttt
     8821 tctactttta acaatatcat caaaaagaga ctgtatgttt tctttcattg tttgattagc
     8881 gggaactatt gggtggtaag tatccatttc atctctgata ccagaaacta aatcattcaa
     8941 ctcattaaca ataaaaccat gtgttatatt actattttct agagaaagca agttttttat
     9001 cgctatgata ttttgtaaaa catcatcatg caaataattt gagaactcca ctctcatgtt
     9061 ttcctctgat ttcataaaat agttcagtct tctattttca tagtcaaaat tttgtttgga
     9121 gttttctaaa taataaaaga tgcaagaaat taccactaga caaaataacg tgcttgcgtc
     9181 aacaattata aaaaataata aaaaatcttt aactaatacc ttcatgagta ccatccaaca
     9241 aaggataaga agtagaaata atagttctat acgagctttg taatcaccta accatctttg
     9301 ggtaacaaaa ctcaatttat catgtatggt cttaaaatag tatattacac tcattataag
     9361 gggaaacaga taccatccca aattattaaa ggattgatta acatctagca tttctccata
     9421 aagttcacta ccaagtatta ccagcaaaag taaagaaaat agtatcaatg aatgtctaac
     9481 aactgatatt tgttgcctaa aggacctata atatagcact ataactagta acggatacag
     9541 gtgtaaaata gtaaaaacca tcaggaataa aaaattaaat aaaattctat taacaaaaag
     9601 gctagttata gaaacaaaaa taattattaa caagccctta tctaacttat ctttaaattg
     9661 tttgtgccca tataatatta aattagtaat ctcaacggta taacaataga gcaatataat
     9721 ctgtagtcca ctgcttaaaa agagaggagt tcctcttgtc agcacagata ctaagtattg
     9781 ccaaattgtt aaggagatga tagaaataat tcttttaaaa atatcacctt gtttttggcg
     9841 taatattgtt gccagccaaa taaaagctgt atcaataagg gtcattacaa gagctacttt
     9901 ttcagagaaa agaagagaca ggttctttcg atgataaatc aaaattaaca aggctattaa
     9961 ttgttgcaac aagattattg cagtcccaaa gaacttactc tttgttatgt tttttattct
    10021 tatcatatta tttacttaat cgttaaagtt aaaagatttt taaaattaat ttttggttat
    10081 ggatgtcact gaccgcaatg tcaatacata aaatgtgcca tatattatca agaagaaaag
    10141 cagacaaagc aataaagata acattatgat attgcctgct accaatgtat ccatgaataa
    10201 atatttatag taaataagca acataccacc atttacaatc ccaatgaata caggaataag
    10261 gaaaagtata cctgtttcat atcgaagaat ccgatgaatc atttttttac tataacctag
    10321 cttacttaga tagccatatt cttctttatt ttccatgatt tcgatgaggc ttgtaaagta
    10381 cagaatacta cctgtacaaa taataaagag tatggatagg aaagttataa agatataagt
    10441 cgcaatatta gcagtcttta ctgtgtattc cttactataa ctactgataa catcaggaac
    10501 catactaaac tgattgtaaa atgcttcact tgacctaatc gaatttccat taaaagtcct
    10561 agttgtcatt tctttctctg gaaaacaaga actaagttta gcatataatt tatcagaaac
    10621 aaccaaggtc gtgacacttg tagaaaaact aaaaacatta tgcgttgata cttgttttac
    10681 agtaacatca tatgcatttc ctaagttaaa ggtttttcca aggctaattt ctgttggata
    10741 ataatttatt aacaatggga gtgacttact accttcaata gaatttattc tcccttgagc
    10801 tttcattaac tctttataat cactgtaatt aattatatca aaataaggaa ttgtttgccc
    10861 agattctgtg atagttactt ctgggttagt gttcaatctc aataggtcaa catcaaccaa
    10921 gctcacttgg tcgttctcta aaatagttgt aacattgact tgaccgtttt ctgatttaac
    10981 attatattct atggcagatg gagtcaacct ctctatccca ttaagagaat aagcatagag
    11041 cattaccatc attccggcaa ctgaaacggt tactgttaaa agacctccca agactgttaa
    11101 taatttattt tttgttgcaa tacgatagtt aaatttggga tagatgatat tagacagagg
    11161 acggtataac ctttttttat ttccttttaa taacgaaact acaaaagcca atccatatct
    11221 gatggtgaac actgttccta aaacaactaa gacaattatc aatagagaaa ccggtaccat
    11281 ccctatgctt aatagcatat ttcgtgtgga tgaaaacact gtcgccaaac ataaaatata
    11341 tgacaatagc aatgcagtga tagcaataat agctctgact tttcttatct taattttttt
    11401 ctcagccttt cttgagaaat taacaaattc aatcaaagac tgtttactaa tgataagtcc
    11461 atttgtgatg acattaatca gaaaaactac gactaatatt cctaaagact ctataatctc
    11521 attagctgta ataaaccact gaacttccaa tgttaattcc aatagatgag taattaccag
    11581 taccgctaaa aaatataagg tcggtcccaa tagtaaactt accaagtaac ttaaaactag
    11641 aataacaaga ttttctaaag tcagtaattg tgttaattct ctttttgaaa accctagtat
    11701 tgctaagact ccaagctctt gactacgttt ttttacaaag aaattattga aataaattaa
    11761 aaatatcacc aaaaatacag tcaaaaaaac taatgacccg ttagcaataa ctagagcttg
    11821 accactatcc ccaatttttt ctgtaatgat tttatctgag ataaaattta gaaaagctat
    11881 aaaaatactt aataaaccaa tcgtagctag aaaatagata cgatataacg aaaagttttt
    11941 tttgatgtta gattttgtaa tggaccaaat catattactc tcctctatcg gataaggctt
    12001 gactaattac atcataaaac gtctctccac aatcctcttt atcaatctcc aggtgaagtt
    12061 taccatcttt gagaagtaca actctatccg cataagaagc tgataaaacg tcatgagtaa
    12121 ccattaaaat agttaccttt tctgttttat tgatttcact caaaatcatc attgtttcct
    12181 cagaagattt caagtcaagt gctccagttg gttcgtcagc aaaaataatc tctggttctt
    12241 taatgattgc tctgataata ctgaccctct gtctttgacc tccagaaagt tgatacggat
    12301 atttcttcaa ctgttcatat aaattaaatc tttttgcata gctatttatc aaatcatcaa
    12361 tctttgaaga atcaatattt tttagagaca aagcaacaga aatattctcc ctaatggtta
    12421 gactatctaa cagcatataa tcttgaaaaa caaaaccaat atcatttttt ctaaaattag
    12481 ttgcctcgtt atcagaaaat gcactaattt ctttgtctgc acaataaata ctcccactat
    12541 caattttatc aataattgaa gtaacattta aaagtgttgt ttttccacta ccgctacgcc
    12601 ccatgacagc tacaaattct cctttttcca caatcaaatt gatatggtct agagcataat
    12661 tcagttgatt gggatatttt ttgcaaacat cttttaatac taattgtttc attttacctc
    12721 ttcctcctga tatttattca tatacgagtc atataagtca caataatcct tattattttt
    12781 gtacaaataa tgatggtttc catagtcaat aattttgcca ttatccatta ttaaaatctt
    12841 atcagctttt tcaactgtat taagtctatg ggtaaccaaa atcctcgtac aatgtaaagc
    12901 ctcaacattt ttttggatta ttctttcagt ttttacatct aaagctgatg taggttcgtc
    12961 aagaactaag attctagggg tggttacaag ttctcttgct agagaaattc gttgtttttg
    13021 ccccccagat agtgatggat tatctcgaaa aagtggagta tgaaacttca ttggcatact
    13081 cctgatatca tcatatattg ataccctttt acaagtttca ataacctgtt ctcctgaaac
    13141 agattctctc cctagcgaaa tgttatacat cacatcccca tcaaatattg gagaatcttg
    13201 agatacaaaa gccgatatat tcttaaaatc agttttatca attttagaga aggtaatgtt
    13261 ctgaggagat tgataaaaac tgataagatt tgcccttttc cctctcccaa tgcttaatcg
    13321 gttttttcaa gactatttca agcaattcac aagtgaactt caatctttca tcgttcaaaa
    13381 tagttatact atcaaataac gaggttgtat ctcctagatt tccaattaat gtccctacag
    13441 aattatagac gtttcctctg gtatccattg aaaagtaagg aatatcacca ttcatcaaat
    13501 ctttaatttc attattaaca ataaaatgtt caatatgttt tgcatcatat agtatcgaaa
    13561 ataaattctt cctctttttt tctgagaaaa gatactttgg attcgtagaa gcttgcaaaa
    13621 attttccata gtcggaagta tttcgaaata gggctctgct tttcaattct gaaaaacctt
    13681 ctactattcc tttaatcttt gaacgttgtg atagaagaaa tatgtagcac tctctaaatc
    13741 ctgaaatgat ctcattagca tagtcaagag gctctaccac tttcccattt aatgtgggaa
    13801 tattgaaccc atcttcttga aaatagtcaa cttttactaa cttcatatct ccacgatttt
    13861 tatttatcag ttcatatttt cctttttttc tttttccacc ttttccactt attccagaaa
    13921 cgttaggagc gctgtttttc tcaaattgta caggaaataa accgtttgaa agtgatgtct
    13981 cataaattct ctgataggtg tctacagtaa tcccttcaaa attctgattt tgtacattca
    14041 actttctttg aaaaaatgtt tcaacgtcaa ttaaatataa atctccgcct gaaacaatca
    14101 cattttccat atgtaagtcc gtaatagaaa atatttcaga aaacgctgct aaaacaccat
    14161 acttaaagta aattttcgct acttcatctt tattggaact tgtataagct acaccaagtt
    14221 gccaacaata atctgcttta actaagcttt taggaagact gaatgagggt atattactag
    14281 atttcaataa actagtaagt tctaacaaga tactgtgtga atgataactt ttaggcttgt
    14341 agtaaacaga tttctcttta aacgcaattt taacgactgt ttgcttttta gagtgactgt
    14401 caccaagtga aaaggcaaca ttgcttaggg gctcactaat gttaaagcac gaccttatct
    14461 cagataagtc ttctaaaaat ctatcaaata ataaagaata tgattcctct atcagtccta
    14521 cttctttatt aatttgtttt agcacatacg gatacctgtc aaaaaaatga tttattccgt
    14581 tttcttctct tatctgctgc atatactgct catatgcctc tgacttattt tcaatttcct
    14641 tggaaaaatg atttatatct aaaactagtg ttttcatcga aaggaacatg atcgtttcaa
    14701 ataactgatt ttcaaactca ctataaaata acttatgtgt ctttttcctt aacacctcac
    14761 tggtttctct aatagaagta tctaatatgt catagtcaaa aattgagtta acgtattcgt
    14821 aaaactgatg gttctgatat tctaacttta attcatctct ttttatcatt tttttcctac
    14881 cactacttaa aaatcctgcc tagactgagt ctaaacagga aatttttagt ctgcttgtcc
    14941 agattgtttt aattaacaac aaacaaatac tgagttcgga cagtcatcag taatagttgc
    15001 aaaccaaccg gaaccttttt taccaccagc tacttccata agttcttttt cagaaacttc
    15061 ttcgataaca ttagtcaaaa tatcctttga atttttcata aaactcattc tcctttccat
    15121 cagtatgtag tgactatttt ctacactttt attgtaaata atacgtcttc attttcaatg
    15181 agtaaaaagt gcaaaaatga cttttttcat attttttagt aagatttttg agatgtcaca
    15241 taagaggtca ctttataaca aatagccctc tgatataaaa aaacaaaact cgttctttac
    15301 agctatttta caatctaatc gcttctcgtt ataacatcaa tctctaatca gaaaatggtt
    15361 actttactta tttaatcagg tcaggagttt gaatgacaga agtcaaatat ctgaaaaagg
    15421 atgttaaata aaactttcaa aacccatttt catcaactaa aaacacttat aacccgatct
    15481 tacaactaat ggattaccat caacagcaaa taatactatg cttgaaaaat gtcaacatca
    15541 tctacttttt gtgactataa ttcagtaaac gaacatgacg tgtagtaaaa atgtattaaa
    15601 gaagtatctc aaaatcattc aatcacttga gtttctgcta cttttttata ccagtaggca
    15661 ctcttcttag gataacgttc ttgagtttca aaatcaacat agaagagacc gtaacgtttt
    15721 tcatagccat ttgaccatga aaagacatcc atcagtgacc acataaagta tcctttaaca
    15781 tttgtaccat cagaaatagc atcagaaata acttctaagt gttttttcac atagtcgata
    15841 cgtccatcat cataaacagt attatctaca aactcatctt tgtaaccaag accattttca
    15901 gtgatataaa ttttcttgta gttaggataa tcggctttga cacgcatgat ttgatcatat
    15961 aagccttgtg ggaagataat ccaatcccag tccgtttttg gaacatcaac gggagctttt
    16021 cttcgaccca cacccttgat ttggtattta gagctgcctt tttccccttt accattatga
    16081 atgatttcag tctcaccatc aaaagcttgc atccaatcac tcatatagta gttaatacca
    16141 aggaagtcat tcaaatcttt tgcagcatcc agtgctacaa agtcttcttc acgaagatca
    16201 agttcaccac catttacctc aaggatatgg ttaacacctt ccattgtttt atctgaatac
    16261 ttacctagat aagttgcatc aaggataaat ttattatgga tgatatcttc cagttcagct
    16321 gctctaacat catcaggatt gttagcgtca aatggatact tagttggaag agcatggaca
    16381 acaccgattt cacctgaata gccactatct ttaaagagtt tgactgcacg agcatgagag
    16441 accatcatgt tatggtgtga ttggaaaact ttagcaagat catattggat acctggaggg
    16501 aatttaccaa ccaagtattg gccatcacca ataggcccaa tttcgttaaa tgttgtccaa
    16561 tagttaactt ctgagaattc tttaaaacag agttctgcat aatttacaaa atgttcaatg
    16621 ttctcacgat tgaggaaatc accatttgaa tgaagtgctt ctggtgtatc aaaatggtga
    16681 agtgtaacaa aaggctcaac atgacgctta tgacactctg caaaaagatt gtggtagtat
    16741 tctactcctt tagggttaac ttctcctttt cctgttggaa aaatacgaga ccaggcaata
    16801 gaaatacgga tgccgttaac accaaattct tcactaagtt tcaaatcgac tggataacga
    16861 ttgtaaaaat cacttgctgg ctcagctgtg taccaatagt tgtcttctaa gtatttatcc
    16921 caagctactg gtcctttgcc atctgtatgg gtagcacctt cagcttgata agcagctgta
    16981 gcaccaccaa aaataaaatc tttaggtaat gtttttgtca tgatatacct cttctaaatt
    17041 ttcatttcac tataaaggaa gattgagtac ccccaacctt ccctagtgaa atattattct
    17101 tccatctgtt ctttaacgaa gtccaatgca ccttgaccat cgcgagtcaa tttgatgtat
    17161 tgagcccctt ctgttttagc taatttaata tcaagtttat cagtttccac tttcatgtct
    17221 tcatagttag aagctacttg aggtgcaagg ataacaagtt gatattgtgg taaaatctca
    17281 cggtgagcac cataacttcc tgctgctgca gtgacaggtg caccatattc tttagctgct
    17341 ttattcaaag cgtttgctaa taaaccactt gtaccaccac cggcacaaag aacgagaaca
    17401 ttagtttgat cagtgatttc tttggtttct ttagctgctg atttttcaag aatagcatca
    17461 gcttttttag tatcaaagtt tgctgctact ttttctttga ggacatctga tgaattcgta
    17521 cctgctgctt cttcagcaag aatttgctca tcatatactt tcaagaatgg gtagtagatg
    17581 atgacatcaa ctacgattaa caaagctgcc aaaatgaatg ctagcacttg gaagtttgtc
    17641 ccaagaataa gacctaatgg agctggtgtt gtccaaggta agtttgcagt gaaactgttc
    17701 attccaagtg tgtcaataaa gaatttgaaa atccatacat tgacaattgg tgctaggata
    17761 aatgggataa agaaaattgg gttcaaaaca agtggagcac cgaacaagat aggttcgtta
    17821 acaccaaaga atgttggaac aactgatgca cgtccaatgg ctttgttacg ttttgatttt
    17881 gttaaccaca tgaacatgaa tggaacgaca agtgttgcac cagtaccacc catggtaacg
    17941 atgaacattt gagtccctga agtcaagatc ttatcagcat gttcaccagc ttgaagtaat
    18001 tgaaggttgg tttcagcatt tgcgtaagta attgctgcaa tggctggttc aacaatagat
    18061 ggtccatgga taccaacaaa ccagaagaga gcaaatgcac cgaagataat agtgattcca
    18121 acataaccat ctgctgcttg gaacaatggt gcaagaagtt taccaattga ctcggcaacg
    18181 ttaacgccta aagtactatg aacaatcaat tcaatcacat aaagcagtac aactgataac
    18241 gtaaatggaa tcaaatcttt aaaaacttga gagatgtttg gtggcacctc ttctggcatg
    18301 cgaatagtga cattgttttt tacacagact ttatagacat ttacggtaat aaaagctgcg
    18361 atgaaggccg ttaacaaacc ttttgttccc ataaatccag ttaagaaacc accgtctttt
    18421 gctggatttg ctgccattag tagaaaacct acaatagcag caagcatggt tgaaataaag
    18481 ttgatttggt tagtgctagg caatgagcgg ttcattgaat cggttaatgc tttggctgtc
    18541 gtaccagcca caaacaaacc taaaataccc attgagtagt tgtatggcgt catcaagaga
    18601 ttctcaatat ccttactcca atggaagccc catgcatttg gaacataggc aatcaagata
    18661 aagatacttg aaaacaagat aacaggcata ccagcgataa aaccatcacg aatagcgcga
    18721 agatagatgt ttcgagaaat tttctcgaag aaaggtttcc ctttctcaat ctgagcaatt
    18781 aatccattca ttattttgct cctctcttat aaagttcaat catgtgtttc attaaatctt
    18841 gtaataaaat ggtcgtcatt aaatgatctt gaccatgcat taaagtgaca ctataagcta
    18901 agtcatctcc agctgcttct ttttgtagta gacttgtctg agcattgtga gcatcattca
    18961 agcagtcact acctgcagcg attaattctt ctgctttagc ataatcccct tcttgcgctg
    19021 ctttaagcgc ttccaaaaat tttgaacggg catcaccagc ataggctacg atttcaaaac
    19081 ctaaaagagt agtttcttct ctattcattg tagtttcctc cgaaaataat gttacatttt
    19141 ttcagtccaa ggacttgcag ttttatctag tactttgttt aattcgtcaa tatttttgaa
    19201 accttctgta cgcaaccatt cacgagctgc ttgtggtcct tcttcgatat agacttttac
    19261 agatcctgcc caagtagcac gtccacataa gacaccgttg aatttagcac ctgattctgc
    19321 tgcaaacacc aaagtatctt ggaacaattt ggcagaaaca ccagcactca aataaatgta
    19381 tggtaaatca gtagaagctt cttgatcacg gaaagcttga gctgcttctt cttttgtaaa
    19441 gagaatctca ccatctgcaa agccttctac aaatttcata tttactggaa cttcaacttt
    19501 caacacgtca actccaaagc gctcttttga gaaaactttc attgcttcgt taactttatg
    19561 agctttaact tttgcaaact cagggcttgc attgtcagca attttctcat cataagttag
    19621 aatttctagg tagaatggaa tatcttctgc acggcattca gaaccaatac gttcaatgta
    19681 agcttttttc tgctcgttaa catcttgatc tccatcaata tcatagtaaa gaaggaattt
    19741 aactgcttct gctccagctt ctttaatacg ttttgcagac caaacatcta agcaatcagg
    19801 taagcgacta gttgttgttg catcgtatcc tgttttctca tatgccaaca acaagcctgc
    19861 ttcttctgaa cgaacacgac ttgctggcaa gccatattca ggatcaagta aaattgatga
    19921 tgcaaatggt gtcagttctt cagaaactaa acttttaagc tcttcaattt gttctactgt
    19981 tggctctttt gtttgatgtt gagccatcat acgtttgaga gctccacgtt ggtcaaaagc
    20041 taaagcagaa ataacaccat ctatacttag tttttccatg cttttacgtt tgttttcagt
    20101 taaagtaatt gtcatttttt atacctcttt gactttaata gattgatata acttatcgta
    20161 atttgccatg ttaacatgcc cagttgtttt ttcttgcgca tttaacatcc ctaagacatt
    20221 tgcttttgtt aataaagctc gatcatcttc atcattcgct aaacctgaag caatacctgc
    20281 cactgtagaa tcccctgaac ctacagcgct tacaattttg attttaggaa tgtcaacttt
    20341 ataaaatgta tccttgtgct ttgcaaatac accatcagca ccgagagaaa cgattatcca
    20401 ttcaattcca tcaaataact tatcttgtaa gacttctttt aaggcatcaa aatcttttgt
    20461 catttctttt ccgagaagtt gagaaagttc ttcaagatta ggcttgataa ctgttggttt
    20521 actatcacct tttagtactg cttctaaagc atttccagaa caatctagaa cagtcttctt
    20581 accattaaga ttggcaatac cgattaactt ctgatagtaa tcatctggca taccagcagg
    20641 cagactgtct gagagcgtca ctacgtcaac atcattcagt aaatatttaa aatgatgagt
    20701 aaatccatca atttcattta cacttaacag cggtcctttt tctaaaatct cagtttgatt
    20761 accttcgtgt aaaatggcta tacaagttct agtatcacct gaaattttat agaagcgact
    20821 taaaatcgaa tcaggaagat gattaatgat aaaatcaccg ctttctccgc caatacaacc
    20881 agtagctttg actgtctcac caaagtcatt tagaactctg caaacattca agcctttacc
    20941 accgggtgtc tttgtaacgt ctacaactcg attgacagta tcgcatttta gctcatccaa
    21001 agggtaggag acgtcaatag ctggatttaa agtaactgtt aaaatcacaa tagctccttt
    21061 ttctctatat ccttatcata attctttcaa atattagtcg tgatattcac cacggtccca
    21121 tttttctaga aattcatcaa agaagtgtgg gttgttttga tcttgattag tatgttgcaa
    21181 gctatccatt ttttcaatcc attttttatt ttcttcagtt ggtttgtatt ccgcggctaa
    21241 gaaagcatcg ataatatcat tcatcaataa accaccgatg atttttccac caaaaccaat
    21301 aacgtttgcg tttagctctt cttttgagta gatagcagat gtcatatctc taacgagtgc
    21361 tgcacgaata ccgggaactt tgtttacagc atttgtgata ccaacaccag taccacagat
    21421 aacaacacct aattctgctt taccacttgc tactgcttca ccaacttttt taccaaagat
    21481 tggatagtgt gtgcgaacat tatcatatgt accacaatca ataactttat gaccttgtga
    21541 ttttaggtaa tccacaacag cgattttttc ataagtaaca atatggtcac aacctacagc
    21601 aattttcatt tttgttctcc ttgttttaac ctatttcaat caattagcac attttattaa
    21661 gcatgtcgac acgaacttga tgacgtccac catcatattt accttcgaca aagcctttga
    21721 taatgttctt tgcaattcct ggagcactaa tttcagaacc aagcgtgatg attcgagcat
    21781 tgttgtgtcc tcttgtcatg tatgctgagc gctcatctga tacttcagct gccaccattc
    21841 ctttgatttt agtagctacc atgaaagaac caacaccata tgcatcaatg acaataccta
    21901 agttatcttc ggaggcatta acttcttttg caacggctaa agttgtatct acaaagtcac
    21961 gtacttcgtt ttcactaaca tcaacgactt cgtatttacc ttctttaagg taatctttga
    22021 taacttcttt aagttcttga cctgctttgt cagcaccgat aataattgcc attttatttc
    22081 tcctatgatt tagaataagt aaatgtggaa aacctacgta gatagttaat taacgatttg
    22141 caacatcttt tgaaataacg ctttcattat ttctatgacc taatcataca cccaccaaac
    22201 ataaaagtca acattttttg tttattttta taaaaaataa acaaaaaaat gtttattttt
    22261 tcatttttac gttattatcc taatatttct tgtgtttctt tttcatttca taaatccctt
    22321 tgacagccac tcgtaaccta tcatatatta cgagaccctt atctctattt attgtaaacg
    22381 ttttatttaa aacattttct attttgttaa tttttgtttt ttccaatatt tatgtttgtt
    22441 ttgtttgatt tttttattga tattatgtta tgataccttt aatagttata ccctaagaca
    22501 ctgataggag ataagaatga aaaagaaaga gcgtcatgaa aaaattctcg atatcttaaa
    22561 agttgacggt tttataaaag taaaagatat tatcgatgaa atgaacatct cagatatgac
    22621 cgctagacga gatctcgata cattggcaga taaaggatta cttatcagga cccatggtgg
    22681 tgctcaatat ttggattatt cttcagcaaa ggacgaaggt cacgagaaaa cacacactga
    22741 aaagaaggtc ttacagacta ccgaaaaaaa acaaattgca caaagagcta aaaacattat
    22801 taaagatggc gaaactgtct ttataggtcc agggacaaca ttagagcatc tagctgtcga
    22861 attaaaaaat agaaatatca gggtcattac aaatagcctt cctgtttttt taattttgca
    22921 cccgtgcact actattgatt tgattttaat tggtggtgaa tgtcgtgaaa ttactggagc
    22981 ttttgttggt gctattgcca ttaataacct agaaacattg acattttcaa aagcttttgt
    23041 cagcgcaaat gcagtttaca ataattctat tgcgacgtac agtgatctcg aaggagaagt
    23101 tcaaagggtt gcattgaata atgctgttga gaaaatcctt ctagttgata gtaccaagtt
    23161 tgaaagttat gacttctata atttctacca actagatcaa gtggacttaa ttgtgactga
    23221 taaaaatgtg acaactaata tcatagaaaa gtacaagaaa ttctcaaaaa tcataatcgc
    23281 tgacaagtaa aagacctact catattaaaa agcacttcag ggtttagata tatcccctgt
    23341 caagtaaaca gggagcatat ctgaaagtag tgtttgtgtt ataaagaagt ttcttgttaa
    23401 cttattttct ggtttttttc agacttatca gtcttgtact gttccttttt ctgatgaata
    23461 acgtggaaat aggcagacag ctatatattt cacctctaga atggttgcca ttactgtcat
    23521 caagacatgc ttgttcttta tcgtatggag tgaagctttc ttttagacat caaaatacct
    23581 cttaagtaga ttttggttcg ttaccatgtc tacttaagag gtgtcttcaa agcgctttaa
    23641 aacgttgata taacagtata ttaacgtttt gagaattgtg aagctttacg agctttttta
    23701 agacctggtt tttggttcac tccattattt aaagtcaaat ccctttaaaa tcaatgtttc
    23761 taaaatgaaa aatcactaaa aatcttattt atagacaaat acttaaacct aaacggtatc
    23821 aaaaataagt ttcggagctt atcaaataat gaaaatctgt ctcaattacc gagtcttttt
    23881 tattgacttt tttgtatata tgatataatt aaataaatta cataaagggg ttacataaaa
    23941 tgactacagt aaaaaaaaac agagcggtta cctttcaagc taataaagaa ttggtaagcg
    24001 aagcaatgac agtattaaac aaaaaaaatt taaccttatc atctgcttta agattattcc
    24061 tacaaaatgt cgttgtcaca aacgaggttg acttattgac ggaagaggag ttagagaaag
    24121 aaaaactttt caaacaattt caagctgaaa tcaacaaaaa tattgaggat gttcgtcaag
    24181 ggaagtttta tacctctgaa gaagtgaggg ctgaacttgg actataagaa atatcagatt
    24241 atctatgctc ctgatgtttt agagaagcta aaagaaattc gtgattatat ttctcaaaac
    24301 tattcctcaa catcaggtca gcgtaaaatg gagcaaatca ttagcgacat agaaaaactc
    24361 gaggttttcc cagaagttgg ttttgatgcc gatgaaaaat atggttcaaa aatcatccat
    24421 tatcacagca ctaaaggtta taccttaagt aaagattata ttgtcctata ccatatcgag
    24481 ggggaagaaa atagggtcgt tattgattac ttgcttccta ctcaaagcga ctatataaag
    24541 ttattcaaat aacacattaa aagccttagc agtcttgcta gggctttttt ggtagattac
    24601 caattaacta ggagcaaaat gagttcgggc tgtttagtag atattccaca aagaagccaa
    24661 agactacgaa gctaggctaa tctaccttaa ggcttcagga aacttggagg agttcaccaa
    24721 gccaactcat aaaacttata gcgagatatt cgagaaatgg tatcaagcct atcatgatac
    24781 ggtagagcca accacggctt ctcgtactct tgatctgttt agacttcaca ttttgccagt
    24841 catgggagaa gtgcccatta acaaaacctc ccctttagac tgctagaact tcatcaccga
    24901 taaagcaaag acctttaaga atatcaagca aatcaagtcc tacactgaaa aggtctttga
    24961 ttttgccatc aagatgaaac tgctcaagca taaccctatg gctgaaatca ttatgccaaa
    25021 gcggaaaaag acacgaatag aaaactattg gacggttcaa gaacttcagg agtttttagc
    25081 catagtactt cagaaagagc cttacaagca ctacgcacta tttcggctac tagcttatag
    25141 cgcggcctta aggaaaggcg agctatgcgc tcttaaatgg gctaatatag actttcagag
    25201 tgagacacta agcgtcaata agagcctagg acgattagac ggacaggcaa tcgaaaaaaa
    25261 gcactaaaaa tgatttctca gtaagaaaga ttaagctaga cagcgaaact ctttccattc
    25321 ttcaagaatg gaaagccatc tgccaaaaag aaaaggcaca actagcagtt gcacctcttt
    25381 caattgagtc tgactttata tttacatact gtactagaga agggagtatt gaaccacttc
    25441 atgcagacta tattaacaat atcttatcaa aggtcattaa gcaacatagt cttaaaaaaa
    25501 taagtcctca cggcttcagg catacccatg caaccctgat gattgagatt ggagttgacc
    25561 cagtaaatac agccaaaaga ctaggacatg ctagtagtca aatgactctt gatacataca
    25621 gtcatgctac tgcagtcgga gaagacaaat caatcaaaca atttgctagc tatctcaaaa
    25681 ataactaaat aaacgtatta aaccaagtca aaagttttcc gaaacggtat caaaaaaggt
    25741 atcaaaagca aaaaacgaca aaaaaagcac cttgcaagag acttgcaaaa tgcttgtaat
    25801 cgttgatgta aagctgttct taacgttttg agaattgtga agctttacga gctttcttaa
    25861 gacctggttt tttacgttca accatacgtg cgtcacgtgt aagaaggcca gcgcgtttca
    25921 atgaatcgcg gaagtctggg tctacttgaa gaagcgcacg agcgatacca tgacggatcg
    25981 cacctgattg tccaccgtaa ccaccaccaa caacgttaac gaaaacgtcg tatgaacctt
    26041 cagttgatgt aactgcaaaa ggttggttaa tgatcaaacg taggtcagca tgtgggatgt
    26101 attcttctac atcttttttg ttaacagtga ttttaccagt acctggaacc aaacgaacgc
    26161 gtgcaacagc gtttttacga cggccagtac ctgcatattg tgcttgtgcc attatttaat
    26221 gctcctttcc tcttagataa gtcctgagat gtcaagtact tctggttgtt gtgctgcgtg
    26281 agtgtgctca ccgccaacga agactttcaa tttcatacct tgtgcacgtc caagagtgtt
    26341 atgtggaagc atgcctttaa ctgatttttc aatcaagcga actgcgtttt tagagcgaag
    26401 ttcaccagca gtgattgatt tcaaaccacc tgggtacatt gagtgagtgt agtaaacttt
    26461 atcagtcgct tttttaccag ttaatttaat tttttcagcg ttgataacga taacaaaatc
    26521 acctgtatca gtgtgtggtg tgaaagttgg tttgtttttt ccgcgaagta cgctagcaac
    26581 tactgcagaa agacgtccaa gtggcacatc agttgcgtca acaacgtacc atttgcgttc
    26641 aacttggcct ggtttagcca tgaaagttgt tttgttcatg atttctccta tacgaattcg
    26701 taatatttgt ttacaaggtg atgggtgttc cgtcccatcg aaggtatttg gaaggttccg
    26761 gggcctttca aatggggtaa acaataccgc ctactatgat atcaaactta agaggctcca
    26821 gtcaagtgct ttagctgatt ttattggatt attttttctt tcgatttagg agaatggcag
    26881 agctgctctg ctgatgttaa cgagaatcat cagcttccca aaaaaggtcg tctaaggtct
    26941 tatcaagcac tcgacaaatg gcaatgcaaa gattaatcgt tgggttgtaa tcaccttttt
    27001 caacagccgc aatggtttgt ctggagacgc ctaccaaatc tgctagagct tgttgagaca
    27061 aatctttgcc tgcacgcgct gcttttaatt tgaggttctt cattcatctg cctctttagc
    27121 atccagataa tgacgataga aaatactagc tcccatacta aggagcgtta tgcccaacac
    27181 cattaaagat ccactgccgc cagccttgaa aaagcttccc attttaagtt gccctgccat
    27241 catctctctt accgccaaac ctatagtgac taaactcatt cctgttgcta tcatccccat
    27301 tagtattcct tgttttccaa agcgcctatc cacaaatgag gaagcaccgt tgaggttaca
    27361 atatgtcgtt tgaactgcca accctcccca taaagccaac gtaaagagga agcttgcaga
    27421 taccagtccc tctgtgaatc ggctaataaa gagtgacagc cagataacca caatcataaa
    27481 ccaaaaccca atagtgtatc ctttgagaag aatctgtttt tggcgttcat catatttggg
    27541 caacttctga tcgtccctta ccttagaatc tagtacttct ttgctatcta gtctcgtttg
    27601 gagctttttc gctgtcttta gcccccatac caacaatatg agaaagctag tcaatataac
    27661 cgctacgcct ccaactaagt aacgttgaaa actggtttta gccagcagtg tcgctactaa
    27721 cacaaccaaa tccatcactg ctattatgat tataaacatc cattgtgact tagcgagatt
    27781 ttgtttgcta tcaaacatga ttcgtttctc ctttaaatct ttacatgaca taatacaaat
    27841 tattttggat attctgtcaa atatatttta cattcttgat tgatttaagc agcaaaaaag
    27901 gattgaggat ttctcttcaa tccttataag ggattaacgg gaattctgcc caatcacaaa
    27961 aactgccagg gtgttaggac caacgtgagc tgagataact ggtcctagtg gcatcataag
    28021 aacatcgcta atattctcat gcgccagtag ctcttctcgc aacttttcgg cactaccctg
    28081 atcgcttgta taagagacaa taaccgtcga atccgcaata tctttttcca cttgagccac
    28141 catttctttg atggcttttt ggcgtccccg aatttttgca atgggtacca atttcccttc
    28201 ctcatcaatc cacaaaagag gtttgatact ggctaaactg cctagaaaag ctgaaccttt
    28261 tgacagacgc ccaccacgca tcaaatgaaa aagatcatct actaagaaat aggtgcgcag
    28321 tcgagggatc actgcttcaa caatatcttt agtctccagt aaatttttgc cactatctct
    28381 ggcttctgct gctaaaatgg ttagatagcc ttctcctcct gcagcagcca aggtatcaac
    28441 aatttcaatc actgcatcgg gataatcttc tcgaacaaga tcgcgtgcca ttagagcgct
    28501 ttgataggta cccgataaaa ccgaagaaaa agcaagataa agcagtgctt tgttgttcct
    28561 agcatgttca cgaaaaacct tctcaaactc tcccacatta atctgactgg tttgaggatg
    28621 actgccagct ttcatctttt tcaaaaggta atcactacta atacggttag gaccgaccgt
    28681 ttcataaacc tctccatcgc acaaaatcgt taatcctata aggacaatat catgatcttc
    28741 tgcccaggtt tgattcaaat cagcggttga atctgtcatt attgtaaagg tcattcttac
    28801 ttctcctcat ccagtttttt agtttgataa tcaaataatt attgttttat tttatcaaaa
    28861 aaacccgcac ttggcgagtc gtaattctca ttatcgatct aactgagaca taaaatcctt
    28921 caattgacta agctgtcctt ggtcaaaagg ccgcagttta ggcgttttga gatcaatatc
    28981 tctagacatt ttatctaaat cagctttgac agtatgaact ctttgctcta attctcttgc
    29041 agtgacacga agagctcctt gagaaaaaat cgtccattgt tcatttaaat cactcgtagc
    29101 tacttctacc atatgtatag ccgtatttaa ctctgctgcc atgcgctcaa tgtaactatc
    29161 tgctgtttcg tcttcctctg taaataccac tgagatataa tactggtcat atcgttgcct
    29221 taaccccggt acatattggg catcaaaaac acaaataata ttaatattct caaaatgggc
    29281 ataatgatta agttttgtta aaagtgtgtt acgtgcctga tcaagctgat ttgtcttaaa
    29341 caactgacgg gttgattgcc aaaaggcaat catattatac ccatctacta ataatatccg
    29401 ttttttcata atttagcgcc tatttcggaa aacttcatac atgagaatag ctgccgctac
    29461 gctagcattt aagctctgta cgtgaccatt cataggaatc gtaatcattt catcaacttg
    29521 ctttttgata ttagtagaga tgcctttgcc ttcgttacca atgactaaag caagtttacc
    29581 attagtgttc cagcaatcag acggtgttcc attcatgtct gtgccaaaaa tccagaatcc
    29641 tcttgctttc aatttatcta gaatttgact aaggttagtt actctcgcta tcggaatatg
    29701 ttcaacagca cctgtagacg tctttgaaac cactggagtc acaccaacag aacgatgttt
    29761 aggaataatc actccacata catttgtagc atcagctgtc cgtaaaatcg atcctaaatt
    29821 atgaggatct gtcagaccat ctaaaataag aatcaaagga tttgcttctt gctctgctat
    29881 ttcgaggatc tcatcaacat cagtataggc aaaagctgat actctcagaa caaaaccttg
    29941 atgcacagct ccatcagtca tttgtgacaa ggttttttta ggcgtccatg aaatagcgac
    30001 ctttttttgt gtcgctaagc ttttgatgtt atccactttc tttcctctta aatcctcttg
    30061 gatataaagc ttatttcctg tatttgcttg aaggctttct gtaacggcat gaacaccata
    30121 gacgatatcg tttgtttcaa tagtatcttt atcttccatg agtttattat accatgaatg
    30181 cttcaaaata aatgcataga ctcttttatt ttcgtctaga tactttttga atagctataa
    30241 ataaacctgc agctaaactg actactagac ctgataagac ccaagggaat cctctttttg
    30301 aagtaggttt tacttcctct ttgtccacta gcatttttgt cttgttgcta ccgttttttt
    30361 ggctattact agcagttggt gtaagtttct catttttagt agatcgcttt aaggaagttg
    30421 atcgatgatt agtagctgat ttgaaaggat ttgaagtaga atctatttct tggttagctg
    30481 attgatttgc ttgagctttt gtgtctacat cgaccgaatt cgtcgttgct ttagaagtat
    30541 ccttttgttg catattagtt ggtgtttttc tagctttgtt ttgatcaaaa tgaacagttc
    30601 ctgattgacc agttactgcc ttttcttgag tatgaacggt gacagttaca tgatagtcac
    30661 cactcttttg tccagttaaa tcaaaccaag ctgtaaaacg acgctgttgc gctgccatag
    30721 tatataccca actattaata gtattatcac tagcgtcttt aagtgttatc gttgcctgag
    30781 ttggttgtct gacaggttga tctgtggtga ctgtagcatc aatataaggt tctgttccac
    30841 gcatactggc ttcaacactg acctgactaa tagttgattc agctataaca ttatcagtgt
    30901 gctgatcttg tgcatacaca gatatggctt tgccagaagt ccccagcaaa ccaataagta
    30961 aagctagtga taataagcta actgtttttt gcatagttgt cataataaat atctcctctt
    31021 taaattagtc ttaccctctc attataaact attcgaaaat gatttcatta tttttatgtc
    31081 ttttttgtta caaatgtatc ttttttatat cattatgtct ttttgatgtc ataaaaagag
    31141 ttaatggctc tctaccttta cttcagacct atgaaaataa gagtctccta ggggactctt
    31201 atgaggatat caattgttgc ttttctacat actcaataca ccatctgatc aattcttcta
    31261 accgctcttt ttggcccatc atatcaagat aacccataat ggcttcaaaa cctgtcgaca
    31321 tacgataggt aataatatcg gcattcttag ctttagtatg gctattggta ttgcgaccac
    31381 gcttatagat gtcttcttct ttttcggtca atagctgcgc ttctaacata gcctgaatca
    31441 agttggcttg tgccttagca gaaacatatc tcgttgctaa acggtgtagc tggctaggtt
    31501 tcgttttacc ttgaaaaatg agatgacgac gaacatagta ggaataaacc gcatctcctt
    31561 caaaggctag ggcaatgcca ttaatcaaat tcacatcaac tggattagtc acgcagccac
    31621 ctcacaccat ctttggtatc tagcagcttg atgccttgag ctgctaactg atctcgaatg
    31681 gcatcagctg tggcaaaatc acgattcgcg cgtgcttctt gtcgcttagc aatcaaggct
    31741 tcaatgtcaa cctcaagcac ctcttcttca aagacaatgc caaaaacagc taacattttc
    31801 tcaaaagcgc ttttaacagg ttctgtatag gagccagaat taatccactt ggccatgtca
    31861 aatacgacgg taatcccatt tgctgtattg aaatcatcgt ccatagcgtc ttggaaagct
    31921 attacaaact gttttagctc ttgctcatct gcagtttctg tcagcggttg ttgcaaggtg
    31981 tttttaagat acttcagatt gatttccgca tcatgaatag ccttttcagt gaagttaatt
    32041 ggttttcggt actgttgtgt cgcaagaaag aatcgcaaaa cctgaccatc aacggtttgt
    32101 aacatgtcat gaacggtcac aaaattacct agtgacttgg acattttttc gttatcaaca
    32161 gtgacaaacc cattgtgcat ccaatagtta gcaaaagtct tgcctgtttt ggcctcagat
    32221 tgggcaattt cattggtatg atgaggaaat tccaaatcag ctccgccacc atgaatatca
    32281 atggtatcac caagaatttc agtagccatc acagaacatt caatgtgcca gcctggacga
    32341 ccaaaccccc aggggctatc ccaagaaacc tcacctgcct tagctgattt ccaaagagca
    32401 aagtccagtg gattttcttt taaagctgtc tcagcatctg ttcgaccact ggctccaact
    32461 tcaagttctg acagggtttt attagctagc ttggcataat gctctgactt ttccacgcgg
    32521 aaatacacat ctccatctgc ttcgtaagca aaatcttttt caatgaggct ttcaacaaat
    32581 gaaatgattt ctgctatata atccataaca cgaggatttt gtgtggctgg cttaacacca
    32641 agtgccttgg tatcttctat aaaagctgca ataaagcgat ctgacaattc tttaggagaa
    32701 acacctgctt gagtagcagc cttgataatt ttatcatcga catcggtaaa attggaaatg
    32761 taattgacct gatagccagt atactcaaaa taacgtcgaa tggtgtcaaa agcgaccgct
    32821 gatctagcat ttccaatatg aatataatta tagaccgtcg gtccacaaac gtacatattg
    32881 actgtatttt cagtcaaagg tacaaacttg cggagcgaac gggtcatggt atcataaatt
    32941 ttaatcatgt aaactcctta ttcaatatcc tagcattagt tgtcatcttg atatcctaag
    33001 tctttttctg aaatgctatt ccaccttttc aacaatttaa tattaataac caaacctatt
    33061 aaccaaaata gggtcaaaat gaagtatata atcgctttaa ccatgtcttg tctcagtaaa
    33121 aagattagac tagccaccag tgtaatacta gaaacaagga tagacgaact cataatgaca
    33181 tacagcccaa ctcttatttt attcatgagg ctcctttatt aacgaaaaac cttcacaacc
    33241 tgtgaaggct tcagaaagta gacaaaccca cttttatgct caaaaagcat gaatagatct
    33301 gctgatttga catcaggttt cctatttctg tatgtggggt gagccaaaac agctgctttt
    33361 tgttgtggta aaagtggcat caatactgac agtgatgccc atacggatgt ttgagacctt
    33421 aggctcaaaa ctaaggcatg gaattccaaa ggaagtcgct gtcgtaagca ccacctgaga
    33481 aaaagtatca caatagactg tttcttcagt ctaagacttg cttagttgat gctcttttac
    33541 gcgttttttg tattttgtaa cattcccata tcactacact cagcaaccaa actgataggg
    33601 ctagctaagt tcaacattac tctactagaa agtcccaaaa tattttattg gaagtcatca
    33661 gcgcttcttt ttgttatttt ccgatcattt tgacaactga taagagacct ctcgttgttt
    33721 ttgtaaactt tgaatttgac gattatcttt ttgcccatgc actcgtacta tcttagctgg
    33781 cacacctaca actgtcacgt cttcaggaac atctgataac acaacagctg ctgcccctac
    33841 tttagcattt gctccgatgt caataggtcc aatcacttgg gcatgtgccg aaattaaggc
    33901 accttgtcga atcgttggat gacgcttgcc acaatctttt ccggttccac ctagggtcac
    33961 cccatgataa agcatcacac ctttttcaac aattgctgtc tctccaataa caagaccagc
    34021 accatggtca atgaagactc caggagcgat ttgtgctcca ggatggattt caatttgtgt
    34081 ccaaaatcgc caaaattggc tatgcattct ggctagtaat ttaaaatgat gtcgccaaag
    34141 aaaatgagac aaacgatgag cagctagggc tttgatgcct ggataagtta ggataacctc
    34201 aagactatta cgagcagctg ggtctagagc tttaacaata gctatacttt ctttccacca
    34261 acccatacta actcctacga cttatctaat tctgaccaat caacaagaat ttgttggtca
    34321 tcaaaaggat tgatggcgac accgaacgtt tcatcaagct cgttttcacc atttcttggt
    34381 tgataaatat catcaatcgt ccaggtcaga atcactcctt cagctttcct gaaaaggcct
    34441 ccaaaatcgt cttggttgta ccatttcgca aagctttgaa gatttgaaaa ggcgggaaca
    34501 tagctttttc cttcaggcgt tgacatggta ggaaaaaggc ggtcgtaatg gttattatct
    34561 ttaggataaa caaaggcagg aacaaggtaa accttttcca tcgtatctgc cgccacattg
    34621 tcatcactca taagcgtatt taacacagtg gtgtaatggt tcataaattg aatcatatca
    34681 ctgcttttga aaatggtaga attcccaaaa tctccctttt tcttaaggtt aaagacaaga
    34741 cctgctgcac cagatgtaat gacttcttct agcactgcaa gagctgaacg ctccagccaa
    34801 tactgacttt gagcactctt ttgttcttct ttaaagcgag ccatatcttc cttatcggta
    34861 aaaacagggg taaccttgac accttcgact tctatcacgt agggttcttt agcagcccag
    34921 acaggaaaat tatggaaagc gttgacaagc gcaaggctat ccaaaaagtt atcaggcgca
    34981 ttgataaaag ctcttaagcg aatatctaat tcatttgatt tagtcatgtt tttcttcttt
    35041 tttctctggt tttggtgggc gtggaatcaa agctttcatt gaggcatcca cacgaccctt
    35101 ctcatcaatc ttaatgacct taacatcaac gtcttcaccc acttcaagga catctgacac
    35161 gttggtcgtt ctagtccaag caatttcaga aatgtgaaca agtgcatctg tcttgtcaaa
    35221 gaggttgaca aaggcaccaa atttctcaat acggacaacc ttagcatggt aaacttcgcc
    35281 taccttagct tcacgtacta ggccagcgat gatttcttta gtgcggttaa tggcagcttg
    35341 gtcacttgag tagatagaga catttccttc gtcatcaata tcaattttga cacccgtttc
    35401 ggcaataatc ttgtcaatag tttcgccacc tttaccgata accactttga ttttgtctac
    35461 gtcaatcttg atggtgtcaa ttttcggtgc agttggggct aactcaggac gtggttcagc
    35521 gatagttgct tcaatcacat caaggatttc aaagcgagct tttttagctt gtgcaagagc
    35581 ttcttctagg atttgaggcg taatccctgc aatcttaata tccatttgaa gggctgtaat
    35641 cccttcacga gttcctgcca ctttaaagtc catatctcca aagtggtctt caagaccttg
    35701 gatatcggtc aagacagtat aatttgtccc atcggaaatg agacccatgg caatccctgc
    35761 cacaggagcc ttgattggta caccaccagc catcagagca agggtaccag cacagataga
    35821 agcctgagaa gacgaaccgt tagattctag aacttcggca actaaacgaa tggcataagg
    35881 aaactcttct aagcttggca agacttgttc aagagcgcgt tcacctaagg caccgtgtcc
    35941 aatttcacga cgaccagcag ctccgtaacg acccgtttca ccaactgaat attgcgggaa
    36001 attgtagtga tgcaagaagc gttttttgta ctctggggcc agaccatcaa tgatttgagt
    36061 ttctcccatt ggtgccaagg tcaaaattga tagcgcctga gtttgaccgc gcgtaaaaag
    36121 acctgatcca tggacctttg gcaagaagtc aaccacagca tcaagcggac gaatttcgtc
    36181 aatcttacga ccgtcaggac gaatcttgtc ctctgtaatg aggcggcgca cttcagcatg
    36241 ctccatttgt tcaaggattt ctgccacgtc acgcataatg gttgctaggt tttcgtcttc
    36301 tgcgtaacgt tcttcgtatt cagccttaac catttcttta acggcttctg tggctgcttc
    36361 acgcgctttt ttctcttcaa cttgaacagc tttttgcagt tgagcattgt acttagccac
    36421 aatatcagct tgtaagtctg catcaacctg taacagttca acctcagctt tttctttacc
    36481 aacaactgct acgatttgtt cttggaaggc aattaattct tgaatagctt ggtgaccttt
    36541 taaaagagcc tcaagcatga tgtcttctga taattctttg gcaccagact caaccatatt
    36601 gatggcttct ttgctaccag caacggttaa ttctaagagt gacgcttcca tttgttcttt
    36661 atctgggttg atgatgaact cgccatcaat atagccaact tgaacacctg caatcggtcc
    36721 attaaatgga atatctgaga tggacaaggc cagagatgag ccaaacatcg ctgccattgg
    36781 agcgctagca ttttcatcat aagaaagaac agtgttagtc acttgtactt cgttacggaa
    36841 accttcggca aacatgggac gaatcggacg gtcaatcaag cgagctgtca aggtcgcatc
    36901 tgttgaaggg cgtccctcac gcttcatgaa acctcctggg aatttaccag cggcatacat
    36961 tttttcttcg taattaactt gaagagggaa gaaatcaccc gttgccattt tcttagacat
    37021 gacagctgcg gtcaggacag ttgattctcc gtaacgaaca acggttgccc cattggcttg
    37081 cttagcgact tgaccaactt caacaac
//
LOCUS       DAXMQE010000017        32189 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.017, whole genome shotgun sequence.
ACCESSION   DAXMQE010000017 DAXMQE010000000
VERSION     DAXMQE010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 32189)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32189)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32189
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.017"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            1..728
                     /locus_tag="ACF4ZO_000996"
                     /pseudo
     CDS             1..728
                     /locus_tag="ACF4ZO_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989109.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003904 - deoxyribodipyrimidine
                     photo-lyase activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="deoxyribodipyrimidine photo-lyase"
     gene            906..2600
                     /locus_tag="ACF4ZO_000997"
     CDS             906..2600
                     /locus_tag="ACF4ZO_000997"
                     /EC_number="5.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016868 - intramolecular
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HFD5486549.1"
                     /translation="MTYNEVYQEWLHNNDLSDDIKADLAAIKDNEAEIQDRFYKTLEF
                     GTAGLRGKLGAGTNRMNTYMVGKAAQALANTIIDHGPEAVKKGIAVSYDVRYQSRTFA
                     ELTCSIMAANGIKAYLYKGIRPTPMCSYAIRALGCISGVMITASHNPQAYNGYKAYWQ
                     EGSQILDDIADQIAQHMAALTQYQEIKQMPFEKALDSGLVTYIDESIEEAYKKEVLGL
                     TINDTDIDKSVRVVYTPLNGVGNLPVREVLRRRGFENVYVVPEQEMPDPDFTTVGYPN
                     PEVPKTFAYSEKLGKAVDADILIATDPDCDRVALEVKNAVGDYVFLNGNKIGALLSYY
                     IFSQRFDLGNLPANPVLVKSIVTGDLSRAIASHYGIETVETLTGFKNICGKANEYDVT
                     KQKNYLFGYEESIGFCYGTFVRDKDAVSASMMIVEMAAYYKKKGQNLLDVLQTIYATF
                     GYYNERQIALELEGIEGQKRIARIMEDFRQTPIASVAEMALDKTIDFIDGYQDFPKQN
                     CLKFYLDDGSWYALRPSGTEPKIKFYLYTIGQTQENSATKLDAIEAACRTKINQVN"
     gene            2808..3662
                     /locus_tag="ACF4ZO_000998"
     CDS             2808..3662
                     /locus_tag="ACF4ZO_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004488 - methylenetetrahydrofolate
                     dehydrogenase (NADP+) activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HFD5486550.1"
                     /translation="MTELIDGKALAQKMQQELAAKVNNLKQKKGIVPGLAVILVGDDP
                     ASQVYVRNKERAALTVGFKSETVRLSEFICQEELIAVIERYNADNTIHGILVQLPLPN
                     HINDKKIILAIDPKKDVDGFHPMNTGHLWSGRPLMVPCTPSGIMELLREYNVNLEGKH
                     AVIIGRSNIVGKPMAQLLLDKNATVTLTHSRTRQLEEVCRCADVLIVAIGQGHFITKQ
                     YIKEGAIVIDVGMNRDDNGKLIGDVAFDEVAEVAAKITPVPGGVGPMTIAMLLEQTYQ
                     SALRSTHK"
     gene            3815..5155
                     /gene="xseA"
                     /locus_tag="ACF4ZO_000999"
     CDS             3815..5155
                     /gene="xseA"
                     /locus_tag="ACF4ZO_000999"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA];
                     GO_function: GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA];
                     GO_process: GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HFD5486551.1"
                     /translation="MADYLTVTHLTKYLKLKFDRDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDESAVIQATMWAGVYKKLGFDLEEGMKINVIGRVQLYEPSGSYSIVIEKAEPDG
                     IGALALQFEQLKKKLTAEGYFEQKHKQPLPQFVSKIGVITSPSGAVIRDIITTVSRRF
                     PGVEILLFPTKVQGDGAAQEVVANIRRANQREDLDLLIVGRGGGSIEDLWAFNEEIVV
                     QAIFESQLPVISSVGHETDTTLADFVADRRAATPTAAAELATPITKTDLMSWIVERQN
                     RSYQACLRRIKQRQEWVDKLSQSVIFRQPERLYDAYLQKIDRLSMTLMNTMKDRLSSA
                     KENKVQLDHALANSQLQTKIERYQDRVATAKRLLMANMARQYDSQLARFEKAQDALLS
                     LDVSRIIARGYAMIEKNQALVASVSQITKGDQLTIKMRDGQLDVEVKDVKNENI"
     gene            5133..5348
                     /locus_tag="ACF4ZO_001000"
     CDS             5133..5348
                     /locus_tag="ACF4ZO_001000"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HFD5486552.1"
                     /translation="MSKTKTFEENLQDLETIVNKLENGDVPLEEAISEFQKGMLLSKE
                     LQKTLQAAEKTLVKVMQADGTEVDMDD"
     gene            5348..6220
                     /locus_tag="ACF4ZO_001001"
     CDS             5348..6220
                     /locus_tag="ACF4ZO_001001"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HFD5486553.1"
                     /translation="MDKLARIDEAIRRYYKTTSNGVSEELIDAILYSVDSGGKRIRPL
                     ILLEMIEGFGVSLQNAHFDLAAALEMIHTGSLIHDDLPAMDNDDYRRGRLTNHKQFGE
                     ATAILAGDSLFLDPFGLIAQAELNSEVKVALIQELSLASGTFGMVGGQMLDMKGENQA
                     LSLPQLSLIHLNKTGKLLTFPFKAAALVTEQAITVRQQLEQAGMLIGHAFQIRDDILD
                     VTASFEDLGKTPKKDLFAKKATYPSLLGLEASYQLLTESLDQALTIFQTLESDVGFKP
                     QIITKLIEGLRLNA"
     gene            6213..7040
                     /locus_tag="ACF4ZO_001002"
     CDS             6213..7040
                     /locus_tag="ACF4ZO_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HFD5486554.1"
                     /translation="MPKERVDVLAYKQGLFETREQAKRGVMAGLVVSVINGQRYDKPG
                     DKIDDGTELKLKGEKLKYVSRGGLKLEKGLHVFGVSVANQIGIDIGASTGGFTDVMLQ
                     DGAKLVYAVDVGTNQLVWKLRQDPRVRSMEQYNFRYAQPEDFNEGQPVFASIDVSFIS
                     LSLILPALHNVLSDQGQVIALIKPQFEAGREQIGKKGIVKDKQIHEKVIQKVMDFASG
                     YGFTVKGLDFSPIQGGHGNIEFLAHLAKSQTPETLAPHLVQEVVAKAHKEFEKHEKE"
     gene            7027..7497
                     /locus_tag="ACF4ZO_001003"
     CDS             7027..7497
                     /locus_tag="ACF4ZO_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HFD5486555.1"
                     /translation="MKKSERLELIKKMVLTHPIETQHDLLRLLAEHGLELTQATISRD
                     MNEIGIVKIPSGSGRYIYGLSQDSGKKIVQGPRSIKSTILAVSDKTKGLEQHLYLKVV
                     PGNSKLIKRYLLADFSKAIFSLIADDDSLLLIAKSPSEADMIRQEILLWMQGIT"
     gene            7519..9180
                     /gene="recN"
                     /locus_tag="ACF4ZO_001004"
     CDS             7519..9180
                     /gene="recN"
                     /locus_tag="ACF4ZO_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HFD5486556.1"
                     /translation="MLLEISIKNFAIIDEISLNFENGMTVLTGETGAGKSIIIDAMNM
                     MLGARASTEVIRRGANKAEIEGFFSVDATPELVACLESSGIAMEEELIIRRDIFANGR
                     SVSRINGQMVNLATLKQVGQFLVDIHGQHDQEELMRPQLHQQILDAFGDKAFEQLKEN
                     YQLIFDRYKSLRRQVIDKQKNEKEHKDRIDMLAFQIAEIEAAALSRGEDDRLNQERDR
                     LMNHKQIADTLTNAYVMLDNDDFSSLSNIRSSMNDLLSIEQFDSEYKGMSTSISEAYY
                     ILEEVSKQLSDTIDQLDFDGGRLQEIEFRLDTLNSLTRKYGGNMNDVLDYYDNIVKEY
                     QLLTGDDLSSGDLEAELKALEKQLVAAATNLSERRHQLAEQLEAEIKAELKELCMEKA
                     DFKVHFTTSKFNRDGNESLEFYISTNPGEGFKPLVKVASGGELSRLMLAIKAAISRKE
                     DKTSIVFDEVDTGVSGRVAQAIAQKIYKIGRHGQVLAISHLPQVIAIADYQYFISKES
                     KEESTVSKVRLLTPEERVEEIASMIAGTDMTQAALTQARELLAKH"
     gene            9352..10293
                     /locus_tag="ACF4ZO_001005"
     CDS             9352..10293
                     /locus_tag="ACF4ZO_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HFD5486557.1"
                     /translation="MTSKKACLSSIIVLASLTCGNDTVSANHLSATGDKFDDCSTLVE
                     KDVAPKDELEMLAWSSSQTTDDADRDYEDFLDDDSFISQNETDKMFENLTDDRLLDEL
                     DELDELDELDEEDTIEPEQNVIMPSDDELFDLTDAVETRLTVSSAPHLEAELPKPHLR
                     SLSDTALRSGEIRGHLDNKLDTLSVTATKLALTMAQKFDLTTHVYSIGESFSEVLAAH
                     YEDRKAESAFSKKKRFHLPIATPDVVIEELRRLVSSIGSSKEDVSVPYNRKLGMAVAK
                     RKIALPQTGEEFSYYPALLGLMILGLTPIMIPKKINN"
     gene            10521..11360
                     /locus_tag="ACF4ZO_001006"
     CDS             10521..11360
                     /locus_tag="ACF4ZO_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002264715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HFD5486558.1"
                     /translation="MGTIKIVTDSSITIEPELIKALDITVVPLSVMIDSKLYSDNDLK
                     EEGHFLSLMKASKSLPKTSQPPVGLFAETYENLVKKGVTDIVAIHLSPALSGTIEASR
                     QGAEIAEAPVTVLDSGFTDQAMKFQVVEAAKMAKAGASLNEILAAVQAIKSKTELYIG
                     VSTLENLVKGGRIGRVTGVLSSLLNVKVVMALKNDELKTLVKGRGNKTFTKWLDSYLA
                     KNSHRPIAEIAISYAGEASLALTLKERIAAYYNHSISVLETGSIIQTHTGEGAFAVMV
                     RYE"
     gene            11353..12195
                     /locus_tag="ACF4ZO_001007"
     CDS             11353..12195
                     /locus_tag="ACF4ZO_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HFD5486559.1"
                     /translation="MNNRHLFSGIFFFVISLCLAFLLLNIIIPKSNSRLKKSDFLKKE
                     QVAIQYVAIGDSLTEGVGDLTHQGGFVPLLTNDLSEYFKANVNHQNYGVSGDTSQQIL
                     DRMIKQKQIQLSLKKADIMTLTVGGNDVMAVIRKNLADLQVSSFRKPARQYQKRLRQI
                     IELARKDNKDLPIFILGIYNPFYLNFPELTDMQKVIDDWNIKTKEVVGEYDRVYFVPI
                     NDLLYKGINGQEGIVHSSGDQTTIVNDALFTGDHFHPNNTGYQIMSNAVMEKIKKHEK
                     KIKP"
     gene            12173..12760
                     /locus_tag="ACF4ZO_001008"
     CDS             12173..12760
                     /locus_tag="ACF4ZO_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HFD5486560.1"
                     /translation="MKKKSNLNWWKWSFLCLLAFNTAFLMVIASRLIQVREPESELIA
                     KKPVKNIKIGTFVTTREQLNETVASYLKDYQTKKMSYKFYATSSSILFEGTYQLLGYE
                     VPLYIYFQPHRLENGAVQLQVISFSVGTLPLPEKDVLQYLKSSYKLPSFVKVMPNQSA
                     IVVNLQDIQNDAKVYLKAKKIDLFNDEISFNIYKK"
     gene            12859..13134
                     /locus_tag="ACF4ZO_001009"
     CDS             12859..13134
                     /locus_tag="ACF4ZO_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HFD5486561.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVDAVFSTIEAFLAEGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGAEIEIAASKVPAFKAGKALKDAVK"
     gene            complement(13223..14365)
                     /locus_tag="ACF4ZO_001010"
     CDS             complement(13223..14365)
                     /locus_tag="ACF4ZO_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFD5486562.1"
                     /translation="MWIEETDNGKFKFRENYKDPYTGTWKPVSVTMEKDNSRAYKAAR
                     KILEQKITEKIAQLKASELLFTELLDEWWAFYKKELKRSSVASLRGNIEEIRETFGIG
                     VKVVNIDPKYVQNYLDNLDCSRNKKERNKSMLNLAFDYAVGLDIIQDNPARRAKLPRV
                     KKTLEDWKKAEEKYLEEDEIKPLLKELYRRPSTYRLGLLAEFISLNGCRIGEAVSIEP
                     CNYESKSRILQLHGTFDHTEGYRNGEKTAPKTLASYRETIMTSRELEILQELEFMNEL
                     EKNTNHRYRDMGYLFTTKNGVPIQTNSFNLALKKANERLEDPITKKLTSHIFRHTLIS
                     RLAENNVPLKSIMERVGHADAKTTAQIYTHVTKKMKSSVADIMENY"
     gene            complement(14489..15007)
                     /locus_tag="ACF4ZO_001011"
     CDS             complement(14489..15007)
                     /locus_tag="ACF4ZO_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIRAN domain-containing protein"
                     /protein_id="HFD5486563.1"
                     /translation="MAKVIFQDNFLLMGTNYHEKEANKVMAEIGKKSPYWDKDKDFIS
                     DYIKSNFKDIYKYYRVSTKDVEIVREPLNRHDPNAIKVMVNKTFVGYFPADLAKRLTP
                     YVKKSSHYQMEATLTGRGGQYKTLKNDLKTVVTKKKDITYKLRLTILKVDRVSKSKNA
                     GLLESIASWFLN"
     gene            complement(15019..15774)
                     /locus_tag="ACF4ZO_001012"
     CDS             complement(15019..15774)
                     /locus_tag="ACF4ZO_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD5486564.1"
                     /translation="MEQLGDRIRKLREGRNMTQTELSEILGMKTYTTVSKWEKNENFP
                     KGKDLKKLAEIFNVTSDYLLGLTDSKLGKITIQNEQPEIVSIYNQLEQPRQEKVLNFA
                     NEQLEEQNKTVSIFDKKSEETEDYITDYVEGLVAAGLGAYQEDNLHMKVKLRSDDVPD
                     EYDTIAKVAGDSMEPLIQDNDLLFIKVSSQVDMNDIGIFQVNGKNFVKKLKRDYDGAW
                     YLQSLNKSYEEIYLSKDDDIRTIGEVVDIYREY"
     gene            15976..16188
                     /locus_tag="ACF4ZO_001013"
     CDS             15976..16188
                     /locus_tag="ACF4ZO_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFD5486565.1"
                     /translation="MVTIAELRAKHNKMSQRELAKELGVTQTSISNWEKDQTKISGEY
                     LISLALFFDVSTDDILGINKQATQKF"
     gene            16458..16769
                     /locus_tag="ACF4ZO_001014"
     CDS             16458..16769
                     /locus_tag="ACF4ZO_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HFD5486566.1"
                     /translation="MPKAEITYRAVDVNETASHGDYKHLIQQWEGLTVATAKQWATEM
                     RDHPDFKQFVLNPTHRIVFIDYKGFKLFVQWKSRNRYKTKKETLPEMLENIKFEKRVG
                     V"
     gene            16771..16956
                     /locus_tag="ACF4ZO_001015"
     CDS             16771..16956
                     /locus_tag="ACF4ZO_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486567.1"
                     /translation="MNKLELFLLATTVILAVIARVQHEVIKKHNSPENKRKIFREVAL
                     KNSKGWSKKRARGGVVS"
     gene            17050..17319
                     /locus_tag="ACF4ZO_001016"
     CDS             17050..17319
                     /locus_tag="ACF4ZO_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HFD5486568.1"
                     /translation="MLLTILSNADEWRVYPEELARRCKDSESAIRSQLKALENAKYIR
                     TYRKSFGGRYGTEAYRFCSDRKISDEAFNTLKAEQDLELEKIANT"
     gene            17460..17846
                     /locus_tag="ACF4ZO_001017"
     CDS             17460..17846
                     /locus_tag="ACF4ZO_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HFD5486569.1"
                     /translation="MDEKKLFENFQLTFGRMISPFEIEDIQKWIHEDNMPIEVVNLAL
                     REAVENNKISWKYINKILVDWYKSGDTTVEKVRDRLQRFDDSKKQRSVTTSNVPSWSN
                     PDYKEPDLEEFALGSMDGIEDGSGDF"
     gene            17827..18060
                     /locus_tag="ACF4ZO_001018"
     CDS             17827..18060
                     /locus_tag="ACF4ZO_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486570.1"
                     /translation="MDQEIFNFFNKQIKKDFGKTASKETFAKFASYCAEGIEKNGVKP
                     IFNWINLYAFGTDITTAEADRLRIERYKQENVL"
     gene            18057..18197
                     /locus_tag="ACF4ZO_001019"
     CDS             18057..18197
                     /locus_tag="ACF4ZO_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486571.1"
                     /translation="MTKQHRETLIWYRASHQERERLLDFGLVDKARYVTLLRQLRKKY
                     AI"
     gene            18206..18412
                     /locus_tag="ACF4ZO_001020"
     CDS             18206..18412
                     /locus_tag="ACF4ZO_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486572.1"
                     /translation="MTPEQAEKAKIRAKQELETFSIYLDQAVDELGGVLTSREVFLAA
                     GFTYLGAGQTDIHAAVEGLCEQIQ"
     gene            18468..18797
                     /locus_tag="ACF4ZO_001021"
     CDS             18468..18797
                     /locus_tag="ACF4ZO_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486573.1"
                     /translation="MNIKEKIVVLRNTEDGSFLKSFKNKKDVLAYNVELTDSIQLASF
                     LPEEAYNIQKEKIDNLAETLGCDVVVIEASYDLKFVDGEDVPELTKEQKVKSMVNGMF
                     EQVFGGE"
     gene            18800..19726
                     /locus_tag="ACF4ZO_001022"
     CDS             18800..19726
                     /locus_tag="ACF4ZO_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006259 - DNA metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
                     /protein_id="HFD5486574.1"
                     /translation="MANQLSTYTHKQFFNAPTVQKAFDDVWKGAGTQFAVSILSVLQG
                     SQSLKSASNKSIYAAAMKAAVLNLPIEPSLGRAYLVPYKGQAQFQLGYKGLIELAQRS
                     GQYKNINAGIVYKSQLISYNPLFEELILDFSKPQDEIVGYFAAFKLFNGFEKVSFWTV
                     EKVTAHGKKFSKSFASGPWKTDFDAMAQKTILKDILSKYGPLSVEMQKAIEEDNQDST
                     ISTPKDITPQEANSLDDLIGHQNENKDAPNNLKDVTEDLHDEEEKTLTDENKTVLEDT
                     SYPADEVPDFDQETGEVLASEGNLFDNLGDLI"
     gene            19723..19923
                     /locus_tag="ACF4ZO_001023"
     CDS             19723..19923
                     /locus_tag="ACF4ZO_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486575.1"
                     /translation="MIKLVKIEGYYINPEYVVGVWERSALNFDDLDEKVVVIQFVGDR
                     EREEFVFCDTPIDEVIKRLLDD"
     gene            19916..20713
                     /locus_tag="ACF4ZO_001024"
     CDS             19916..20713
                     /locus_tag="ACF4ZO_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease-like domain-containing
                     protein"
                     /protein_id="HFD5486576.1"
                     /translation="MTSLDLLGKDYYSRESAIRYWSISQYKRFKECEARALAELQGNW
                     TDTRDNTALLVGNYVHSYFESKKAHEEFKAQNGSEMISTRGATKGQLKKDYLVAEQMI
                     DALKSDSNFMAIYQGEKEAAITGFLGEIEFKGKIDCLNVERGYFVDIKTTKGPIDDTI
                     WSGEERVRWFEAYGYILQMAAYKTMLEAKYNKPFEPIIYAVTKETPPDTRAIRIQNVD
                     AMQNELDSLAQSIKRLDDVKKGIEKPKPCGHCEYCRANQLTQRVMIF"
     gene            21078..21473
                     /locus_tag="ACF4ZO_001025"
     CDS             21078..21473
                     /locus_tag="ACF4ZO_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cas9 inhibitor AcrIIA9 family protein"
                     /protein_id="HFD5486577.1"
                     /translation="MDELKEKALSKMLDEMNKKHSAAEDAIHNWLSDQDDEELFKGIL
                     DDKKSIKDAMKYCINQAQKQKTGNCAMVDDKTVFGWVRVYFTGKTKKIEPVQATVTVS
                     QENTKVIPKKNKKSKGVVEGQLDLFGALV"
     gene            21470..22816
                     /locus_tag="ACF4ZO_001026"
     CDS             21470..22816
                     /locus_tag="ACF4ZO_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfJ domain-containing protein"
                     /protein_id="HFD5486578.1"
                     /translation="MKKNQKIIEGRLKPPKAFFDWCYEQIPTIRWQNKEKTIETEREH
                     KVYIDNRRLTKRTRLDFFDKFYSFAIVLVTSKRIEIQSYGFYSRYSNGRQSIEVKLCN
                     FEKLANNHHIKLTEQFGQYVPGLTPNFIGSGAYSGTKFYPDDWEEKIKSISELKYLQF
                     PIGLAHHNLPHMYKYRTQIEFLQKIDAWKIANDLAYDVTEYDAWHVRKAVDCRVITKK
                     WLHQNKQFFKNSNRSFREYELERRIKARNGKLVPGIEKILSYQDINKIPKAAKINRFQ
                     NWLVKNKVDFNYYIDYLSMLDELGIEIDTDNLIMPKDLVKAHDNVVKLVNQKKSEIEK
                     RKFKNRLKSLSKYEQTIGDYCFRAPVDSGELIREGKTLSHCVGSARYTQAHASGKTTI
                     IFIRRKSDSDKPFYTMEYKAGHIVQVRGKHNQSATEEVQKVVDQWLAIVNKNYKHA"
     gene            22827..23159
                     /locus_tag="ACF4ZO_001027"
     CDS             22827..23159
                     /locus_tag="ACF4ZO_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486579.1"
                     /translation="MITKINVPKTSIVIEIENKEITIENLINYDIKMIFRNQDNEPSL
                     DENGDIFEPMYWLDIKAKPNDEIEYHSSLGVKKEKRRLAELQIFFEYIEANKQNLFDL
                     CGLKGELA"
     gene            23156..23668
                     /locus_tag="ACF4ZO_001028"
     CDS             23156..23668
                     /locus_tag="ACF4ZO_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486580.1"
                     /translation="MSSLTLSLDVSTTGTGWAIFDGSTLIQSGASKPKQKSFYERAKS
                     MASELKTIQLRAIQKHDKPFEDIVIEQNTVLGPNQQSSIKIGIATGIILGRLLAEEIY
                     FVNVSTWRKYWKFSYKDRSKKSMKKQAINAVAAEFNKQVKDDEADAILIGSYFTNLGK
                     DFGDLESHKN"
     gene            23704..24021
                     /locus_tag="ACF4ZO_001029"
     CDS             23704..24021
                     /locus_tag="ACF4ZO_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1372 family protein"
                     /protein_id="HFD5486581.1"
                     /translation="MEIVKDGVKFIASMIIVLAATFGCGYLFYRAGYEQAKKEVQPVT
                     IYTVDNVGGVMVGEITDKEIIEGRYTVTAHAYGKFLVTKEQYKAIKVGDKIPDYLKKR
                     GTK"
     gene            24018..24173
                     /locus_tag="ACF4ZO_001030"
     CDS             24018..24173
                     /locus_tag="ACF4ZO_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486582.1"
                     /translation="MIELTQKQADYVEFVRKTIVDPDMMEFAVNTQLISYALLVGYCI
                     VDEEVAK"
     gene            24170..24421
                     /locus_tag="ACF4ZO_001031"
     CDS             24170..24421
                     /locus_tag="ACF4ZO_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486583.1"
                     /translation="MKPRKYPYSGKIRIIKKELPRFVRLGDFAFNSNLVKHIDKIRQV
                     KPNETLIRFKIPKLFMTYEEETFKVRLEIDKVVKILNQY"
     gene            24497..24916
                     /locus_tag="ACF4ZO_001032"
     CDS             24497..24916
                     /locus_tag="ACF4ZO_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HFD5486584.1"
                     /translation="MSKAKAILKDLRNLDLYIASLIRRQEKIETSLLSSPKWSSDKVN
                     GGIKRKQDDVYVELIATAEDIEKKTAEAIRKQRELQNLIDSLENTDSQTILSMVYIDK
                     MTRWQVIDELNCSESTYFRLLRVATKELNNLTVNDSD"
     gene            25024..25368
                     /locus_tag="ACF4ZO_001033"
     CDS             25024..25368
                     /locus_tag="ACF4ZO_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease signature motif containing
                     protein"
                     /protein_id="HFD5486585.1"
                     /translation="MSQLRADKKGTHRVAFEKNKRKLLKTTNLCGICGKPVDKTLKYP
                     HPLSAAIDHIVPIAKGGHPSALENLQLTHWQCNRQKSDKLFANQASNEPKTIGNRNLP
                     QSRDWSSFTLKK"
     gene            25516..25872
                     /locus_tag="ACF4ZO_001034"
     CDS             25516..25872
                     /locus_tag="ACF4ZO_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486586.1"
                     /translation="MKKKCLICKKNFQAKTNRTLYCSEECRKKGNREKQRKLMKQKRA
                     EQRKEKKKVLNPNTDVTEKPKKIRNLAQHYKKLKKEILANESEFGFTGITLIEGIDVH
                     EENFVDLVMQKIKEQK"
     gene            25869..27137
                     /locus_tag="ACF4ZO_001035"
     CDS             25869..27137
                     /locus_tag="ACF4ZO_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HFD5486587.1"
                     /translation="MNYMGMGYLRRKLALFKTGVDKRYRYYAMDDRDDTRSIVMPNNV
                     REMYRSVLEWTAKGVDSLADRIIFREFTNDDFNAWEIFKANNPDIFFDTAIQSALIAS
                     CCFVYIMPGAEDGLPKMQVIEASKATGILDPTTFLLTEGYAILESDSNGNPTLEAYFT
                     DKDIWYYPKKGKPYNIKNPTGHPLLVPIIHRPDAVRPFGRSRITKAGMYHQKAAKRTL
                     ERAEVTAEFYSFPQKYVLGMDPDAEPMEKWRATVSTLLEISKDEDGDKPTVGQFTTAS
                     MAPFMEHLKMYASLFAGGSGLTFDDLGFPSDTPSSVESIKAAHENLRAAGRKAQRSFS
                     SGFLNVAYIAVCLRDEFPYLRNQFMDTVIKWEPLFEADANMLTLVGDGAIKLNQAIPG
                     FMDADVIRDLTGVKGADKPIPAITEVTTDG"
     gene            27130..28623
                     /locus_tag="ACF4ZO_001036"
     CDS             27130..28623
                     /locus_tag="ACF4ZO_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486588.1"
                     /translation="MVDDVLPKLLKSVRQDFEKYFGESDVVTKAFAELQAKKVTYKTV
                     NEFAIEVGRLLSLALTGSVSSDKLPDGKMYYNIAKRLLDETMGRNYKLISGYAGDVQR
                     ILNENAQIGLKVQRPPLNRDKINGMVNRLDSENTFDDVKWLFGEPIVNFSQSIVDDTI
                     KANADLQYKTGMTPQVVRTESGNCCEWCREVVGTYSYPKVPKDVWRRHQRCRCTLDYD
                     PKNGKVQSAWSKIWRKKEKTQESIERVEKFKESALVESIKNDIAKLDMTKVGPSDIID
                     IGKRINYHFRVSEHIGDKEKLKEIFSNFREIGGEIPKNTWAKGSSKLVKDQLQEAFQN
                     YPTEWAAVPDGIGKKLKAIKRKRGYFDGYDEDLVIATNGTRKTTPYHEIGHMIELVNP
                     DLVRLEKAWVDKRTANEAEVRLKDIFPSSNYGIGEVTKKDDFISPYIGKYYSDAAEVF
                     TMGLQGIFVPEERFAKSFDKKTWKYDYKTINDDPEFLNFIIGLFVKV"
     gene            28629..28853
                     /locus_tag="ACF4ZO_001037"
     CDS             28629..28853
                     /locus_tag="ACF4ZO_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486589.1"
                     /translation="MEPKLHRQLRQKYDDAEKQYLEKFGEDSLDRVFFWEPDVYFDEW
                     KKVLPDATLELNKAINSGVAIDPDPENAIY"
     gene            28930..29082
                     /locus_tag="ACF4ZO_001038"
     CDS             28930..29082
                     /locus_tag="ACF4ZO_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486590.1"
                     /translation="MTWENKDEFQQIMNKVNETKEAYEKALEAAENFVPKMSCATKLN
                     KGEGNE"
     gene            29075..29341
                     /locus_tag="ACF4ZO_001039"
     CDS             29075..29341
                     /locus_tag="ACF4ZO_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486591.1"
                     /translation="MNKRIKKKRKLETAIMLLIAENALQAEAIKNQNKEIMELKSIVQ
                     RNALATNEELATVKAATLDNQSVIKAIGDTVDYIKKNYKRKWGK"
     gene            29343..29558
                     /locus_tag="ACF4ZO_001040"
     CDS             29343..29558
                     /locus_tag="ACF4ZO_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486592.1"
                     /translation="MKYRKKPVVVEAIQFTGTNYEKIKEFIGQNTLCSTLSIVIPTLE
                     GDYIIKGIAGEFYPCKPDVFEQTYEST"
     gene            29640..31055
                     /locus_tag="ACF4ZO_001041"
     CDS             29640..31055
                     /locus_tag="ACF4ZO_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase"
                     /protein_id="HFD5486593.1"
                     /translation="MVTKTKTKLGNQRPTQSVNLHFAKSLAHEAINYYKKTGLSCYPW
                     QVNMLIPIMAIDENGLWVHQKYGYAIPRRNGKTEVVYIVELWALHKGLKILHTAHRIS
                     TSHASFEKVKKYLEMSGYVDGEDFISNKAKGQERIEFKASGAVIQFRTRTSNGGLGEG
                     FDLLIIDEAQEYTSEQESALKYTVTDSDNPMTIMCGTPPTMVSTGTVFEAYRKDCLKG
                     NKRYSGWAEWSVPEMVKINDVSSWYISNPSMGFHLNERKIEAELGEDEIDHNIQRLGY
                     WPSFNQKSVISEKEWAKLKVEQVPELKSKLFVGIKFGQDGNNVSLSIAARTSENKVFV
                     ETIDCLSVRNGTQWIINFLKSADIAKVVIDGASGQELLAQEMKEQGLKKPELPKVAEI
                     ITANMMWEQGIMQETICHSDQPSLTAVVTNCEKRQIGSNGGFGYKSLYDDRDISLMDS
                     ALLAHWICYTTKPKRKQRTSC"
     gene            31136..31597
                     /locus_tag="ACF4ZO_001042"
     CDS             31136..31597
                     /locus_tag="ACF4ZO_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HFD5486594.1"
                     /translation="MSEFKVIETQEELDTIVKARIAREREKYQDYDQLKTRVEELETE
                     NSSLQTALNDAKSNTDSYTEEISTLKNQIADYETANLRTKVALQYGLPIDLADRLQGD
                     DEDGLKVDAERLASFIKPSQPQPPAKSNEPNIDSNADANYRALVQGLSTED"
     gene            31622..>32189
                     /locus_tag="ACF4ZO_001043"
     CDS             31622..>32189
                     /locus_tag="ACF4ZO_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HFD5486595.1"
                     /translation="MGTETSKASLFDKHLVSDLINKVKGHSSLAKLSSQKPIPFNGSK
                     EFTFTLDSDIDVVAENGKKTHGGLSLEPVTIVPIKVEYGARLSDEFLYATEEEKIDIL
                     KAFNEGFAKKLARGIDLMAMHGINPRTKKASDVIGTNHFDSKVTQVVKFTESEDADAN
                     IEAAVNLIQGAEGVVTGLAMDTEFSTALA"
BASE COUNT        10924 a         5339 c         6744 g         9182 t
ORIGIN      
        1 cgagtcggtt gtctcctttt ttaagaatag gagctattgg cattcgcacg gtatatcacg
       61 ctgtgcgtca agcaccaaat agtctagggc aagctacttt tttaaaagaa ttagcttgga
      121 gagactttta caatatggtc tatgtggctt atcctgatca gaaaactcag cctatccaaa
      181 aagccttttc tcaaatcgaa tgggttaata atcctgactg gtttcagttg tggaaagaag
      241 gtaaaacggg ttaccctatt gtcgatgctg caatgcttca gttacaaaag acaggatgga
      301 tgcataatcg tttacgaatg atagtagctt cttttttaac taaagatctt ttatgtgatt
      361 ggcgtttagg agagcagtat tttcaacaat aactaattga ttatgatgct gccagtaata
      421 tcggaggatg gcagtgggct gcttccactg gaacagatgc tgttccttat tttagaatat
      481 ttaatcctgt tactcaaagt aagcgctttg atcccaaagg cgagtttatt aaagcgtatt
      541 tgcctcaact agaacacgtt ccagagaagt atctccacga accgtggaag atgccaaaat
      601 accttcaaga gagtgtgtcc tgtattattg gcacagacta tcctcaacca attgtcgatc
      661 atgctaaaca acgtgaacaa gctattgcaa agtatgagtg ggcaaaagaa aaagcaaaaa
      721 tagaatgact gttctcatta taagagttta aacaaaaagt tatcatgaat taagattatt
      781 taatttaaaa aataagttga ctttatttag attatttgat actattcagt tgtctccctt
      841 agagaaagcg atttcttttt ttggagctga tttttaccat ttggtcttag aataggatga
      901 gtaatatgac ttacaacgag gtatatcaag aatggttgca caataatgat cttagtgatg
      961 atattaaagc agatttagca gccataaaag acaatgaggc tgagattcaa gatcgttttt
     1021 acaaaacact tgaatttgga acagcagggc taagaggaaa acttggagca ggcaccaatc
     1081 gcatgaatac ctatatggtt ggtaaggcag cacaagcttt agctaatact attattgatc
     1141 atggacctga agcagttaaa aagggcattg cggttagtta tgatgttcgc tatcaatcta
     1201 gaacatttgc agaattaaca tgctctatta tggcagctaa cggtattaag gcgtaccttt
     1261 ataaagggat tcggccaaca ccaatgtgtt cgtacgctat tcgtgctttg ggatgtatct
     1321 ctggtgttat gattacggct agtcacaatc cccaagctta caatggttac aaagcttatt
     1381 ggcaagaagg ttctcaaatt ttggatgaca ttgcggatca aattgcacaa cacatggctg
     1441 cactaactca gtatcaggaa atcaaacaaa tgccttttga aaaggctctg gacagtggac
     1501 ttgttactta tattgatgag agtattgaag aagcatataa aaaagaagtg cttggtttaa
     1561 cgattaatga tactgacatt gataagtcag tccgagtagt ctatactcct ttaaatggtg
     1621 ttgggaatct accagtgcgt gaggttttaa gacgccgcgg ttttgaaaat gtttatgtgg
     1681 tacctgagca ggaaatgccc gatcctgatt ttacgacagt tggctatcct aatcccgaag
     1741 tccctaaaac ttttgcatat tcagaaaaat taggtaaggc agttgatgct gatattttga
     1801 ttgcaactga tccagattgt gaccgtgtgg ctttagaagt taaaaacgca gtcggtgact
     1861 atgtttttct caatggcaat aaaatcggag cgcttttatc ttactatatc ttttcacaac
     1921 gatttgactt aggtaattta ccggctaatc ctgttttagt gaaatccatt gtaacaggag
     1981 acttgtcacg ggctattgct agccattatg gtattgaaac cgttgaaaca ttgactggtt
     2041 ttaagaatat ttgtggcaag gcaaacgaat atgatgtgac gaaacagaaa aactatctgt
     2101 ttggttatga agaaagtatt ggtttttgct atggcacttt tgttcgtgac aaagacgctg
     2161 ttagcgcctc tatgatgatt gtagaaatgg cagcttacta caagaaaaag gggcagaatt
     2221 tactagatgt tttgcagact atttatgcga catttgggta ttataatgaa cgtcaaattg
     2281 ccttggagct tgaggggata gaaggacaaa aacgcattgc gaggataatg gaagatttca
     2341 gacagacacc aatagctagt gttgcagaga tggcgttaga caagacaatt gattttattg
     2401 atggctatca agattttcca aagcaaaact gtctcaaatt ttatttggat gatggttctt
     2461 ggtatgcact tagaccatca ggaacagagc ctaaaataaa attttattta tatactattg
     2521 gccaaacaca agaaaatagt gcaacaaaat tagatgctat tgaagcagcg tgtcgcacaa
     2581 aaataaatca ggttaattaa acatcaaaaa tggataacac ttttacacta tttttccata
     2641 taaacaacta caaaaggagg tgagactttt aggcaccttc tttttcttgt aggtgtcact
     2701 aatcaattta atcgactcaa accaatacta aaaaataagt aagagtataa agaacaggca
     2761 tctatttttt tgttataata gaaaaatgaa attaaaggga gatgtcaatg acagaactaa
     2821 ttgatggtaa agccttagct caaaagatgc agcaagagtt agcagctaaa gtcaacaatc
     2881 taaaacaaaa aaaaggaatt gtaccaggct tagccgttat tcttgtaggt gatgatcctg
     2941 ctagtcaggt gtatgtccgt aataaagagc gtgcagctct tactgtaggt tttaaaagtg
     3001 agaccgttag attatcagaa ttcatttgtc aagaagagct tattgcagta atcgaacgtt
     3061 acaatgcaga taacactatt catggtattt tagtgcagtt acccctgcca aatcatatta
     3121 atgataaaaa aattattctc gccattgatc ccaaaaaaga tgtggatggt tttcacccga
     3181 tgaatacagg tcacctttgg tcaggacgtc ccttaatggt tccttgtact ccatcaggga
     3241 ttatggaatt gcttcgagaa tataatgtta accttgaagg taaacatgcc gtcattattg
     3301 gcagatcgaa tatcgttgga aaaccaatgg cacagctctt actggacaaa aatgcaacag
     3361 tcacgttgac acattcaaga acacgtcaat tagaagaagt atgtcgctgt gcagatgtgt
     3421 tgattgtggc aatcggacaa ggtcatttca taacaaaaca atatataaaa gagggtgcga
     3481 tagtgattga tgtgggaatg aaccgtgatg ataatggcaa gctaattgga gatgtggcct
     3541 ttgatgaggt ggcagaagtt gcagcgaaaa tcacccctgt accaggaggt gtcggtccta
     3601 tgacgattgc tatgttgcta gagcaaactt atcaatctgc cctccgtagt actcataaat
     3661 agttataatt agacaattca acataagaga atataagaag tcagcaatgg cttccttttt
     3721 tgtttttctg ctcactattt atccagaaaa atggtataat tgcattagta tgcaaaggga
     3781 ctatgtcagg tccaactaag tgaaaggtgg cttgatggca gattatttaa ccgtcactca
     3841 tttgacgaaa tatttaaaat taaaatttga ccgtgaccct tatttggaac gggtttatct
     3901 gactggtcaa gtgtccaatt ttcgaaaacg accaactcat caatattttt ccttaaaaga
     3961 tgaaagtgct gtgattcaag ccaccatgtg ggcaggagtc tataaaaaac taggattcga
     4021 cctagaagaa ggcatgaaaa ttaatgtaat tgggcgagtc caactttatg aacctagtgg
     4081 ctcttactct atcgtgattg aaaaggcaga gccagatggt ataggtgcct tggctttgca
     4141 gtttgaacaa ttaaagaaaa aattaacggc agaaggttat tttgagcaaa aacacaagca
     4201 gcccttgcca cagtttgtat caaaaattgg ggtcattaca agtcctagtg gtgctgtgat
     4261 tcgagatatt atcacaaccg tttcacggcg ttttccaggg gttgagattt tattattccc
     4321 aactaaagta caaggtgatg gagccgccca agaagtagtg gctaatattc gaagagccaa
     4381 tcaaagagag gatttggact tgctcattgt cggccgtgga ggtggctcga tagaagacct
     4441 ttgggccttc aacgaggaaa tagtggttca ggctatcttt gaatcgcaac ttccagtgat
     4501 ttcgagtgtg ggtcatgaaa cagacacgac tttagcggat tttgtggcag atcgcagagc
     4561 agccacacca acagcagcag cagagttagc aacgcctatt acaaaaacag atcttatgtc
     4621 ttggatagta gagcggcaaa atcgttccta tcaggcctgc ttgaggcgga ttaagcaacg
     4681 gcaagagtgg gtggataaac tctcgcaatc tgttattttt aggcaaccag aacgattata
     4741 tgatgcctac ctgcaaaaaa ttgatcgcct tagcatgacc ctgatgaata cgatgaaaga
     4801 tcgtctgagt tccgccaaag aaaacaaggt tcagttggac catgccttgg ccaatagtca
     4861 attacagaca aaaatcgagc gataccaaga ccgtgttgct accgctaagc gtttactgat
     4921 ggctaatatg gctaggcaat atgatagtca gctggctcgc tttgaaaaag cacaggatgc
     4981 tttgctttca ctggatgtca gccgaattat cgcccgtggt tatgcaatga ttgaaaaaaa
     5041 tcaagcactg gtagcctctg taagtcagat aacaaagggt gatcagttaa ccattaagat
     5101 gcgtgatgga caattagatg tagaggtaaa agatgtcaaa aacgaaaaca tttgaagaaa
     5161 atttacaaga tttagagact attgtgaaca aacttgaaaa tggggatgtc cctttggaag
     5221 aagctatttc agaatttcaa aaaggaatgc ttctctcaaa agaacttcaa aagaccttac
     5281 aagcggcaga aaaaacactc gtcaaagtga tgcaagctga tggcacagaa gtagatatgg
     5341 atgattaatg gacaaattag ctagaattga cgaagccatt cgtcgctact ataagacgac
     5401 tagtaacggt gtatctgaag agttgattga tgctatcttg tattctgttg acagtggtgg
     5461 caagcgcatt cgcccactta tcttattaga gatgattgag ggatttgggg tatcgttaca
     5521 gaatgctcat tttgatttgg ctgcagccct tgaaatgatt catacaggaa gtctgattca
     5581 cgatgatttg ccagccatgg ataatgatga ttaccgacgt ggtagactga ccaatcacaa
     5641 acaatttgga gaggctactg ctattttggc gggagatagc ttatttttag acccctttgg
     5701 gttaatagct caagctgaat taaatagcga ggttaaagta gccttaatcc aagaactttc
     5761 cctagcttca ggaacttttg gcatggttgg tggtcagatg ctagatatga aaggggaaaa
     5821 tcaagctttg agtctccctc agttgtcact gattcacctc aataaaaccg gaaaattatt
     5881 aacttttcct tttaaagcag cagctcttgt aacagaacag gctattactg ttcgtcaaca
     5941 actagagcag gcgggaatgc tcatcgggca tgcctttcag attagggatg atattttaga
     6001 cgtgacagct agctttgaag atcttggaaa aacgcctaaa aaggatttat ttgcaaaaaa
     6061 agctacttac ccaagtttac tggggttaga agcctcctac caactgttga cagagagttt
     6121 agatcaggct ttgacgattt ttcagacact cgaaagcgat gtcggcttta agcctcaaat
     6181 aattacaaaa ctgatagaag ggttacgact taatgcctaa agaaagagta gatgtgttag
     6241 cctataagca aggattattt gagaccagag agcaagctaa gcgtggtgtt atggcaggct
     6301 tagtggtctc tgtgattaat ggccaacgct atgacaagcc aggtgacaaa attgacgatg
     6361 ggactgagtt aaaacttaaa ggtgaaaaac tcaaatacgt cagtcgtggt ggattaaaac
     6421 tggaaaaggg gctgcatgtt tttggtgtat cggttgctaa tcaaattggg attgatattg
     6481 gcgcttcaac aggtggtttt accgatgtta tgttacaaga tggggccaaa ctagtctatg
     6541 ccgtcgacgt tgggactaac cagttggtat ggaaactcag acaagatcca cgagtaagaa
     6601 gtatggaaca gtataacttt cgttatgctc agccagagga ctttaatgag ggacagcctg
     6661 tatttgccag tattgatgtg tcctttattt ctctcagctt gattttgcca gccctgcata
     6721 acgttttgtc agatcaggga caggttattg ctctcattaa accgcaattt gaagctgggc
     6781 gcgagcagat tggtaaaaaa ggcatcgtca aggacaaaca gattcatgaa aaagtgattc
     6841 aaaaggtcat ggattttgcc tcaggttacg gatttacagt taagggactt gatttttccc
     6901 ctattcaggg tggtcatggc aatatcgaat ttttagctca tcttgctaag tcacagacac
     6961 ctgaaacgtt agccccgcat ttggttcagg aagttgttgc caaggcacat aaggagtttg
     7021 agaaacatga aaaagagtga acgacttgaa ttaatcaaaa aaatggtttt gacgcatcca
     7081 attgagacgc aacacgacct cttaagatta ttggcagagc atgggttaga attaacccag
     7141 gctactattt caagagacat gaatgaaatt ggtatagtaa agattccttc tggcagtgga
     7201 cgttacatct atggtctttc tcaagatagt ggaaaaaaga tcgttcaagg acctagatcg
     7261 ataaagagca ctattttagc tgtatctgac aaaacaaaag gtttagaaca acacctctat
     7321 ttaaaagtcg tacctggcaa tagtaaatta atcaaacgtt atttattagc agatttttca
     7381 aaagctattt ttagtcttat tgctgatgat gatagtttac tgttaattgc aaagtctcct
     7441 tcagaagcag atatgatacg ccaagaaatt ttgctttgga tgcagggtat aacctagaaa
     7501 aaaatagggg agaaagtgat gttattagaa atttctatta aaaattttgc tattattgat
     7561 gaaatttccc taaattttga aaatggtatg acggttttga cgggtgaaac tggagcagga
     7621 aagtctatta tcattgatgc tatgaatatg atgcttggtg cgcgtgctag tacagaagtg
     7681 attcgtcgtg gagctaataa agcagaaatt gaggggttct tttcggtaga tgctacccca
     7741 gaactggttg cgtgtctgga atcatcaggt attgctatgg aagaagaact gattattcgc
     7801 cgggatatct ttgccaatgg cagaagcgtg agccgcatta atggtcagat ggttaaccta
     7861 gccaccttaa aacaggtcgg acagtttttg gtagatattc atgggcaaca tgaccaagaa
     7921 gaattaatgc gaccacagct ccaccagcaa attttggacg cttttggtga taaggctttt
     7981 gagcaattga aagagaacta tcagcttatt tttgatcgtt ataaaagctt gcgtcgccag
     8041 gttattgaca aacaaaaaaa tgaaaaggaa cacaaagatc gtattgatat gttggccttt
     8101 cagatagcag aaattgaagc tgctgccttg agtcgaggtg aggacgaccg gttaaatcaa
     8161 gaacgtgatc gcttaatgaa ccacaaacaa attgctgata ccctgaccaa tgcctacgtc
     8221 atgctagata atgacgattt ttcaagccta tccaatattc gctctagcat gaatgactta
     8281 ctatcaattg agcagtttga ttcagagtac aaagggatgt cgacttcgat ttctgaagcc
     8341 tattatatcc ttgaagaagt gagcaagcaa ttatcagata ccattgacca actggatttt
     8401 gatggtgggc gattacagga aattgaattt cgcttggata cactcaatag cttaacccgt
     8461 aaatacggtg gtaatatgaa tgatgtgctt gactactacg ataatatcgt caaagaatac
     8521 cagctattaa caggagatga cttgtcttca ggggatctag aggcagaatt gaaagcctta
     8581 gaaaaacaat tggttgctgc agccactaac ttgagtgaac gccgccatca attggcggag
     8641 caattagaag ctgagattaa agctgaactt aaggaacttt gtatggaaaa agcagatttc
     8701 aaagttcact ttaccacatc aaaattcaat cgtgatggta atgaaagctt ggaattttac
     8761 atctctacta atccaggcga aggattcaag ccccttgtca aggtggcttc tggaggagag
     8821 ttatcacgcc ttatgttagc catcaaggct gctatttcta gaaaagaaga taagacgagt
     8881 attgtttttg atgaagtaga tacaggtgtt tctggtcgcg ttgcgcaagc cattgcccaa
     8941 aaaatttata aaattgggcg acatgggcaa gttctcgcta tttcacactt acctcaagtt
     9001 attgctattg ctgattatca gtattttatt tctaaagaaa gtaaagaaga gtccaccgtt
     9061 tctaaggtaa ggttattaac tcctgaagaa cgtgtggaag aaattgctag catgattgca
     9121 ggaacagata tgacacaagc tgctcttacg caggctcgtg aactacttgc caaacattaa
     9181 gattatgttt ggtatttgat attttcataa ttagatgaaa ttgatttttt aggtgctaaa
     9241 ataatcattg tgctagacca tttttcctct gttaatcggg cttggtttgc cttgacaaac
     9301 ctctgagaaa tagtagaata gataagagaa ttttaagctg aggggataga aatgactagt
     9361 aaaaaagcgt gtttatcaag tatcattgtg ttagcaagtt taacgtgtgg aaatgatact
     9421 gttagtgcca atcatctctc agcaactgga gataagtttg atgattgctc aacacttgtt
     9481 gaaaaagatg tggcccctaa agatgaactt gagatgttag catggtcctc gtctcaaaca
     9541 actgatgatg ctgacagaga ctatgaagat tttctcgatg atgattcttt tatttctcaa
     9601 aatgaaactg ataagatgtt tgagaattta actgatgata ggttattaga tgaattagat
     9661 gaattagatg aattagatga attagatgaa gaagatacaa ttgagccaga gcaaaatgta
     9721 ataatgccta gtgacgatga gctatttgat ttaactgatg ctgttgagac acgccttact
     9781 gtttctagtg ctccccattt agaggctgaa ttgccgaaac cacatttgag gagcctatca
     9841 gatacagcac tgcggtctgg tgaaattaga ggacatttag ataacaaact ggacactttg
     9901 tctgtaacag ctacaaagtt agcattaacg atggctcaaa aatttgattt gacaacgcat
     9961 gtctattcta taggtgaaag ctttagtgaa gtattagctg ctcattatga agacagaaaa
    10021 gcagaatcag ctttttctaa gaaaaagaga tttcaccttc ctattgctac tccagatgtt
    10081 gttatagagg agttaaggcg cctagtctct tctattggaa gttcaaaaga agatgtttca
    10141 gttccttata atcggaagct aggtatggca gttgcaaaaa gaaaaatagc cctgccacaa
    10201 acgggagagg agttctctta ttatccagct ttacttggtt taatgatatt aggattaacg
    10261 ccgattatga taccaaagaa gataaataat taggtaataa gttattgtag ttgtaaaaga
    10321 cggggcaaat gttcaagcgt gaaaaggttg acttttgcct cgttttgtat ctcgttattg
    10381 ctaaggcatt ttcttcgagc agctagtgct cgccatacct atctaccgag tgattattca
    10441 atagcactac cagttttgct ttatttagta aggagtgtta gaataaagag gtgagaaact
    10501 agtttagaat ggaaaaatac atgggaacta taaaaattgt tacagattca tcaataacta
    10561 ttgaaccaga attaattaaa gctttagata ttactgtagt gcctttatct gtcatgattg
    10621 atagcaaatt atattctgat aatgatttaa aagaagaagg tcattttttg agccttatga
    10681 aggctagcaa atcccttccc aaaaccagtc agccaccggt tggtctcttt gctgaaactt
    10741 acgaaaattt ggtcaaaaaa ggagtaactg acattgttgc tattcacctc tcaccagctt
    10801 tatcaggtac tattgaagct tcccgtcagg gggctgaaat cgctgaggca cctgttacag
    10861 ttttagattc aggatttact gatcaagcca tgaaatttca ggtcgttgag gcagcaaaga
    10921 tggcaaaagc gggtgctagt ttgaatgaga ttttggctgc tgttcaagct atcaaatcaa
    10981 aaacagagct ctacattggt gtatctacct tagaaaattt agtaaaagga ggtcgtattg
    11041 gtcgtgtgac gggtgttttg agctcgctac ttaatgtcaa agttgttatg gcacttaaaa
    11101 atgatgagtt aaaaacgctt gtcaaaggtc gaggtaataa aacatttacg aaatggttag
    11161 atagttacct cgctaaaaat agtcatcgcc cgattgcaga gatagctatt tcttatgctg
    11221 gtgaagctag cctggcatta accttaaaag aaagaatcgc agcttattac aaccactcta
    11281 tttcggtttt agaaacaggc tctatcatcc aaacacatac aggagaagga gcttttgcgg
    11341 ttatggttcg ttatgaataa tcgtcattta tttagtggga tatttttctt tgttattagt
    11401 ttatgtctgg cctttttatt gctaaatatt attatcccta agtcaaattc acgtttgaaa
    11461 aagagtgatt ttctgaaaaa agaacaagta gctatccaat atgttgctat aggagattca
    11521 ttgacagaag gagtaggtga tctaactcat caaggtggtt ttgttccttt gttaacgaat
    11581 gatctcagtg aatattttaa ggctaatgtt aatcatcaaa attacggcgt atctggtgat
    11641 accagtcaac agattcttga taggatgata aaacaaaagc agatacagtt atctttaaaa
    11701 aaagcagata taatgacgtt aaccgttggt ggtaatgatg ttatggcagt tattcggaag
    11761 aatttagcgg atttgcaagt ttctagtttt agaaagccag ctcgtcagta tcaaaaacga
    11821 ttaagacaga ttatcgagtt agccagaaaa gataataaag atcttcctat ttttatttta
    11881 ggcatctata atccgtttta tttgaatttt ccagaactaa ctgatatgca aaaagtgatt
    11941 gatgactgga atatcaaaac taaggaggtt gttggagaat acgatcgtgt gtactttgtg
    12001 ccaataaatg acctcttgta taaagggata aatggacaag aaggaattgt ccattcttca
    12061 ggagatcaaa ctacaattgt caatgatgcc ttgtttactg gggaccattt tcacccaaat
    12121 aatactggct atcaaatcat gtcaaatgca gtaatggaga aaattaaaaa gcatgaaaaa
    12181 aaaatcaaac cttaattggt ggaagtggag cttcttatgt ctgcttgctt ttaataccgc
    12241 ctttttgatg gttattgcaa gtcgtctcat tcaagtaaga gaacctgagt cagaactgat
    12301 tgctaaaaaa ccagttaaaa atatcaaaat tggtacattt gtcacaacca gagaacagct
    12361 taacgaaact gtagcaagtt atcttaaaga ttatcagact aaaaaaatgt cttataaatt
    12421 ttatgcgaca tcttcttcta ttttgtttga aggaacttat caattattag ggtatgaagt
    12481 ccctttatat atctattttc aacctcatcg tctagaaaat ggagctgtcc aactacaggt
    12541 gatctctttt tcagtgggaa ctctgccact cccagaaaaa gatgttttgc agtatttgaa
    12601 atcaagctac aaattgccaa gctttgttaa agtgatgcca aatcaatcag ctatcgttgt
    12661 taatttacaa gatatccaaa atgatgctaa ggtttattta aaagccaaga aaattgattt
    12721 atttaatgat gaaatcagtt ttaacatcta taagaaataa gctcaaataa cgttaaatac
    12781 ttgacctaat cgcttttttt agatatgata atatctgtta aagcattaag cttactaatt
    12841 atttggagga tttgttaaat ggctaacaaa caagatttaa tcgcaaaggt tgcagaagca
    12901 actgaattga ctaaaaaaga ttcagcagca gcagttgatg ccgtgttttc tacaatcgaa
    12961 gctttccttg ctgaaggtga aaaagtacaa ttgatcggtt ttggtaactt cgaagtacgc
    13021 gaacgtgcag ctcgtaaagg tcgtaaccca caaactggtg cagaaattga aattgcagct
    13081 tcaaaagttc cagccttcaa agctggtaaa gctcttaaag acgctgttaa ataattgcat
    13141 atataaaagc ccattgtaca agcgttgtag cctgtgcagt gggctttttt gtgttcaggg
    13201 gggtaaaaaa ggggtaaaaa atttaatagt tttccataat atcagctaca cttgatttca
    13261 ttttctttgt gacatgagta taaatttggg cagtagtttt agcgtctgca tgtcctacac
    13321 gttccatgat tgattttagc ggcacgttat tctctgctag acggctaata agagtgtgac
    13381 ggaagatgtg gctagtaagt ttttttgtaa ttgggtcttc caatctttca ttagcttttt
    13441 ttaaagctaa gttgaatgag ttagtctgaa ttggaacacc gttttttgtt gtaaaaaggt
    13501 atcccatatc tctatatcta tgatttgtat ttttttctag ttcgttcata aattctaact
    13561 cttgtagaat ttcaagttct ctacttgtca tgatggtttc acgataagaa gctaatgtct
    13621 ttggtgctgt cttttccccg ttacgatatc cttctgtatg atcaaatgtt ccgtgcaact
    13681 gcaatattct tgacttagat tcgtagttgc acggctcaat gctgacagct tcaccgatac
    13741 gacaaccgtt caaactgata aactcagcca acaaaccaag tcggtaagtg ctaggtcttc
    13801 tgtacaattc tttcaataat ggtttaattt catcttcttc aagatatttt tcttcagcct
    13861 ttttccagtc ttcaagagtt ttctttaccc ttgggagttt agcacgtctt gcaggattat
    13921 cttggataat atccaaacca acagcataat caaatgctaa gtttagcata gacttattac
    13981 gctctttttt attcctagag caatctaggt tatcgagata attctgaacg tatttaggat
    14041 caatattcac tactttaaca cctattccaa aagtttccct tatctcttcg atattacctc
    14101 tcagagaagc tacagacgac cttttaagtt ctttcttata aaacgcccac cattcatcta
    14161 aaagttccgt gaaaagtaac tcagaggcct ttaattgcgc tattttttct gttatttttt
    14221 gttcaaggat ttttcgagct gctttataag ctcttgaatt atccttctcc atagtaacgg
    14281 atacaggttt ccatgttcca gtgtaaggat ctttataatt ttcacgaaat ttgaatttac
    14341 cgttatcagt ttcttctatc cacatttgtt ttttacctca ttttctgtta aaataggtat
    14401 agtaaagaga cctactgcga agcaggtttt tactatacta gattcgcctc acgctctcct
    14461 cgccaaattt gagcgtgggg cttttttgtt agttgagaaa ccaagatgct atcgactcta
    14521 ataatccagc atttttactt tttgatactc tatctacttt taaaatagtc aatcgtaact
    14581 tataagttat atctttcttt ttagtaacca cggtctttaa atcgtttttg agtgttttgt
    14641 attgtccacc acgaccagta agggttgctt ccatttggta atgactagat ttttttacat
    14701 aaggggttaa tcgtttagct aagtctgctg gaaagtagcc aacaaaagtt ttgtttacca
    14761 tgacttttat ggcatttgga tcgtgacgat taagaggttc tctgacaatc tctacatctt
    14821 ttgttgagac cctgtaatac ttgtagatat ccttgaagtt tgattttatg tagtcagaaa
    14881 taaaatcttt atccttatcc cagtatggtg atttcttacc aatttcagcc ataactttat
    14941 tagcttcttt ttcatgataa tttgttccca ttaagagaaa gttatcttgg aatatgactt
    15001 ttgccataac agtctccttt aatattccct ataaatatcc acaacttcac cgattgtgcg
    15061 gatgtcgtca tcctttgata gatagatttc ctcatagctt ttatttaaac tttgcaagta
    15121 ccaagcgcca tcataatcac gcttgagttt ttttacaaag tttttaccat tgacttggaa
    15181 tatccctata tcattcatat cgacttggct agataccttg atgaatagca aatcgttgtc
    15241 ttgaataagt ggttccattg aatcgccagc tacttttgca atagtatcat actcatcggg
    15301 gacatcatca gaacgtagtt taactttcat gtgtaaattg tcttcttggt atgccccaag
    15361 accagcggca accaatccct caacgtagtc agtgatataa tcttctgtct cctcagattt
    15421 tttatcgaat atagaaacgg ttttattttg ttcttctaat tgttcgttag cgaagttgag
    15481 gactttttct tgtctaggtt gttctagttg gttgtatata gaaacgattt caggttgttc
    15541 gttctgtatt gtgattttcc caagtttact atctgtgagt cctaaaagat agtcagaggt
    15601 aacgttgaaa atctctgcta gtttttttag gtctttacct tttggaaaat tttcattctt
    15661 ctcccacttt gaaacagtag tataggtttt catgcccaat atttctgaaa gttcagtctg
    15721 agtcatgttg cgcccttctc tcaactttct tattcggtcc cctaattgct ccataggata
    15781 cctccttttt aattttgata agtaaattat atcaaaacca tgattataaa tcaactatat
    15841 aagaaaaaag ttttaaataa actatatgat ttacgatttt ttcaaaaaaa cagaaaataa
    15901 atcatataaa acacttgacg caagatttaa aatcatatag aatgtaatca tcatcaagaa
    15961 aggagcgact cagctatggt aactattgca gaattaagag ctaaacataa taagatgtca
    16021 cagcgtgaat tggcaaaaga attaggtgtt actcaaacat ctatcagcaa ctgggaaaaa
    16081 gaccagacaa agatttcagg tgagtatctt attagtctag ctttgttttt cgatgtatct
    16141 accgatgaca ttcttgggat aaacaagcaa gcaacacaaa aattttaaac actatatgat
    16201 tttaaatcat atagtagaaa ggacacacat gaacgaaata acatttaccc tatattgcac
    16261 aacatctgaa gaagcaatca cggaagtaaa gaaactaaaa gaagcccatc caaaggatag
    16321 acttcgattc aatgtaaaca ttaagcctga gttttactaa tagaaccaac ttaattagat
    16381 aataaaaagt ccgacgggaa tcggactcca aacaaaaaat atttacttaa ttataacaca
    16441 agagagagga tattaatatg ccaaaagcag aaattactta tagagcagtt gatgttaatg
    16501 aaacagcttc tcatggtgat tataaacact tgattcaaca atgggagggg ttgacagttg
    16561 ctactgcaaa gcagtgggcg acagaaatgc gtgatcatcc agactttaaa cagtttgtat
    16621 taaatccaac gcatagaatc gtattcattg attacaaagg attcaaactg tttgtacagt
    16681 ggaaatctcg caatcgttac aaaacaaaaa aagagacact gccagaaatg cttgaaaata
    16741 ttaaatttga aaaaagagta ggagtataac atgaacaaat tagaattatt tttgttagca
    16801 acaaccgtta tcttagcggt cattgctagg gtgcaacacg aagtcattaa aaaacacaat
    16861 tcgccagaga ataagcggaa aatttttagg gaagtagctt taaaaaacag caaaggatgg
    16921 agcaagaagc gtgcaagagg aggggttgtc agctaatgca gtacattttt caagacatta
    16981 acaggtagtt acacagctgt tagcaatgaa tttattcagg acaaagaact tttcaataag
    17041 gaaaaaggac tgctgctaac cattttgagt aatgcagacg aatggagagt ctatcctgaa
    17101 gaactcgcta gacgttgtaa ggatagcgaa tctgcaatca gaagccagtt gaaagcgtta
    17161 gagaatgcca agtatatcag aacttataga aaatcatttg gcgggcgata tggtaccgaa
    17221 gcctatagat tctgttctga cagaaaaata agcgacgagg cgttcaatac tttgaaggca
    17281 gaacaggact tagaactaga aaaaattgct aatacctaat ttgctaatgt gcaatttgct
    17341 aatgtgcaat ttgctaatca acaaattagc caactaataa atactaactt ataaataaat
    17401 actaaataac aataaatact aacagataat aagcatcatc atcaacatca ggaggagcta
    17461 tggacgaaaa aaagcttttt gaaaatttcc aattaacttt tggacggatg atatcgccat
    17521 ttgaaatcga agatattcaa aagtggattc acgaagataa catgccaatt gaagttgtca
    17581 accttgcctt aagagaagcg gtagaaaaca acaaaatcag ttggaagtat atcaataaaa
    17641 tcttagttga ttggtataaa tctggagata cgacagtaga aaaggtcaga gacaggttgc
    17701 aacggtttga cgatagtaaa aaacaacgaa gtgtaactac ctcaaacgtc ccaagctggt
    17761 cgaatccaga ctacaaagaa ccagatttag aagaatttgc tctaggaagc atggacggta
    17821 tagaagatgg atcaggagat ttttaatttt tttaacaaac aaatcaaaaa agattttggt
    17881 aaaacggcga gtaaagagac ttttgctaag tttgctagtt actgcgctga aggaatcgaa
    17941 aaaaatggag ttaagccaat ttttaattgg ataaacctat acgcttttgg aactgatata
    18001 acaacagcag aagcagaccg attaaggata gagcgatata aacaggagaa tgtgttatga
    18061 caaaacagca tagagaaacg cttatctggt accgagcaag tcatcaagag cgtgagagat
    18121 tgcttgattt tggactagtt gataaagcac ggtacgtgac actattgcgg caattgcgta
    18181 agaaatatgc gatttaggag gaaatatgac accagaacaa gcagaaaaag caaaaatcag
    18241 agctaaacaa gaacttgaaa cgtttagcat ataccttgac caggcagttg atgaactcgg
    18301 tggagtttta acttcgcgag aagtcttttt ggcagcggga ttcacctacc ttggcgcagg
    18361 tcagacagat atacatgctg cagtcgaggg attatgtgag caaatccaat gattttaaat
    18421 ttagtgaaga ctgggagagc aactaaaaca caaaaagagg aaatgaaatg aacatcaaag
    18481 aaaaaattgt agtgctaaga aacactgaag acggaagttt tttaaagagt ttcaaaaaca
    18541 aaaaagatgt acttgcttat aatgtggaac ttacagatag cattcaactg gcatcatttt
    18601 taccagaaga agcttacaac atacaaaaag aaaaaattga taatttggca gaaacgcttg
    18661 ggtgtgatgt tgtagttatc gaagcatcat atgacctaaa atttgttgat ggcgaggatg
    18721 ttccagagtt aacaaaagag caaaaagtta aaagtatggt aaacggaatg tttgagcagg
    18781 tttttggagg tgaatagaga tggcaaatca attatcaaca tacacacaca aacaattttt
    18841 taacgcacca acagttcaaa aagcttttga tgacgtttgg aaaggcgccg ggacacagtt
    18901 cgcggtaagc atcttgtcag tactacaagg tagtcaaagt ttgaaatcgg catctaataa
    18961 atctatttat gcagcagcta tgaaagcagc cgtgttaaat ctgcctattg agccaagctt
    19021 aggaagggcc tatttagttc cgtacaaagg tcaagcacaa ttccaattag gctataaagg
    19081 gttgattgag ttagcgcagc gcagcggaca atacaaaaat attaatgcag gtatcgtcta
    19141 taaatcacaa ttaatttctt acaacccttt gttcgaggaa ttaatccttg actttagcaa
    19201 gccacaagat gaaattgtag ggtattttgc cgcttttaaa cttttcaatg gattcgagaa
    19261 agtttctttt tggacagtag aaaaagtaac tgcacatgga aagaaatttt caaaatcgtt
    19321 tgctagcggt ccttggaaaa cagactttga tgcaatggct caaaaaacta ttttaaaaga
    19381 tattttgagt aaatatggtc cgttatcagt tgagatgcag aaagctatcg aggaagataa
    19441 tcaagattca acgatttcta ccccaaaaga cattacccca caagaagcaa atagccttga
    19501 cgacctaatt ggtcaccaga acgaaaataa ggatgctcct aacaatttaa aagacgtaac
    19561 tgaagattta catgacgaag aagaaaaaac gctcacagac gaaaataaga cggttttaga
    19621 agatacgtct tatccagcag atgaggttcc cgattttgac caagagactg gtgaagtatt
    19681 agctagcgaa ggcaacttat ttgataacct cggagactta atatgattaa acttgtaaaa
    19741 attgaaggat attatattaa tccagaatat gttgttggcg tttgggaaag atctgcttta
    19801 aattttgacg atttagatga aaaagtagtg gttattcaat tcgttggaga tagggaaagg
    19861 gaagagtttg tcttttgcga tacacctatt gatgaagtaa ttaagaggtt gctagatgac
    19921 tagtttagac ttgctcggaa aggactatta cagccgtgaa tcagctatca ggtactggtc
    19981 cattagtcag tacaagcgtt ttaaagagtg cgaagcgcgg gcgcttgctg aattacaagg
    20041 gaattggaca gataccagag ataacactgc gttgctcgtc gggaactatg tccactctta
    20101 ctttgagagt aaaaaagctc atgaagaatt caaagcccaa aacggctctg aaatgatttc
    20161 gacccgagga gcaacaaaag gccaattaaa aaaggattac ttagttgctg aacagatgat
    20221 tgacgctctt aaaagtgata gtaactttat ggctatctac caaggagaaa aggaagcagc
    20281 aatcacagga tttcttggcg agattgaatt caagggtaaa atcgactgcc tgaatgttga
    20341 acgtggctat tttgtagaca tcaaaacaac aaaagggccg attgacgaca cgatttggag
    20401 tggcgaagag cgtgtcagat ggtttgaggc ttacggatat atcttgcaga tggctgctta
    20461 caaaaccatg ttagaagcca aatataataa accgttcgag ccgattattt acgcggtaac
    20521 caaggaaacg ccaccagata caagagccat cagaatccaa aatgtagacg ctatgcaaaa
    20581 cgagttagat agcctagcac aaagcattaa gcgattagat gacgttaaaa aaggcataga
    20641 aaaacctaag ccttgcggtc attgcgagta ttgcagggct aatcaattaa cacaaagagt
    20701 aatgattttt taggagataa aataatgata atagagagga ataagcggag gatatggtaa
    20761 gaagtgagta tgctagagct aaccacatct ctaaagaatg ggtagtactt tactagaaaa
    20821 gtggaggaat ttaaatgatt gaattcgtaa aagaagtagg aatggctttg ttatggctgt
    20881 ttgtaggata tcttgttgga gagcgtagcc aacaaaaaaa taagtaaaaa atacgtgccg
    20941 tgaaccacga aaaaagcgaa ctagaaataa gtgtcattta acggtcatgt gactagaatg
    21001 atgtaaagaa tagcgactgc ccgtatttag ccaaattaac aacttttggc agtcgctttt
    21061 agttttaggg aaatgctatg gatgaattaa aagagaaagc attatccaaa atgctagatg
    21121 aaatgaacaa aaaacatagt gcggctgaag acgccataca taattggcta tctgatcagg
    21181 atgacgaaga actattcaaa ggcatacttg acgataagaa atcaattaaa gatgccatga
    21241 agtactgcat caatcaggca caaaaacaaa aaacaggtaa ttgcgccatg gttgacgata
    21301 aaacagtatt cggttgggtc cgtgtgtatt tcactggaaa aaccaaaaag atcgaaccag
    21361 ttcaagcaac tgtcacagtt agccaagaaa atacgaaagt tataccaaag aaaaataaaa
    21421 aatcaaaagg tgtggttgag ggccaacttg acctatttgg tgcgcttgta tgaagaaaaa
    21481 ccaaaagatt atcgaaggtc gtttaaagcc acctaaggca ttctttgact ggtgctatga
    21541 acaaataccc accatcagat ggcaaaacaa ggaaaagaca atcgaaactg aacgtgaaca
    21601 caaagtctat attgataata ggcgcttgac taagcggact agactagatt tctttgataa
    21661 gttttacagc tttgctattg tccttgtcac ttccaagcga attgaaattc aatcctatgg
    21721 cttttactcc agatatagca atggaagaca atcgattgaa gtgaagttgt gtaactttga
    21781 aaaattggcc aacaatcatc acatcaaatt gactgaacaa tttggccagt atgtgcctgg
    21841 attaacacca aattttatag gctctggagc ctattcaggt accaaatttt atcctgatga
    21901 ttgggaagaa aaaatcaagt caatatcaga actgaagtat ttgcaatttc cgatcggctt
    21961 agcacatcat aacttgcccc acatgtataa gtacagaacg caaatagagt tcctacaaaa
    22021 aatcgatgct tggaagatag caaatgattt ggcttatgat gtgactgaat acgatgcttg
    22081 gcatgtacgg aaagccgtag attgtcgagt gattaccaaa aaatggttac accagaacaa
    22141 gcaattcttc aaaaacagta acaggagttt tagagaatat gagcttgagc gtcgaattaa
    22201 agctagaaat gggaagttgg ttcctggtat tgaaaaaata ttgtcttatc aagacatcaa
    22261 taaaattcca aaagcggcca aaatcaacag gtttcaaaac tggttggtta agaataaggt
    22321 agattttaac tattatatcg attatctgag tatgcttgat gaattaggta ttgaaattga
    22381 cactgataat ctgattatgc caaaagacct agtaaaggcc catgataatg ttgtcaaatt
    22441 agtcaatcaa aagaaaagcg agattgaaaa acgcaaattt aaaaatcgtc tcaaaagcct
    22501 ttctaaatat gagcaaacga ttggcgatta ctgtttcaga gcacctgtcg attcaggaga
    22561 actcatccga gaggggaaaa ctctatctca ctgcgtagga agcgcacgat atacacaggc
    22621 ccacgcttct ggaaaaacaa ctattatttt tatccggaga aaatctgatt cagacaaacc
    22681 attttacaca atggagtata aagccggcca tatcgttcaa gtcagaggca aacataatca
    22741 gtcagctact gaagaagtcc aaaaagtagt tgatcagtgg ctggccattg taaacaaaaa
    22801 ttataaacac gcataggaga aataacatga taacaaaaat taatgttcca aaaacatcca
    22861 tcgtaattga aattgaaaac aaggaaatca cgattgagaa tttgattaat tatgatatta
    22921 aaatgatttt cagaaatcag gataatgaac cgtctcttga tgaaaacggg gacatctttg
    22981 aaccgatgta ctggctagac ataaaagcta aacctaatga tgagattgag tatcacagca
    23041 gcttaggcgt caaaaaagaa aagagaagac tcgctgaact acaaatcttc tttgaatata
    23101 ttgaagcaaa taaacaaaat ctctttgacc tctgtgggct aaaaggagaa ctcgcatgag
    23161 tagcttgaca ttatcacttg atgtctctac tactggaacg ggttgggcta tttttgatgg
    23221 ttcaactcta atccagagcg gggctagtaa accaaaacaa aaatcattct atgagcgtgc
    23281 caaatcaatg gctagcgagc taaaaactat ccaacttaga gcgattcaga aacatgataa
    23341 gccttttgag gacattgtga ttgaacagaa cactgtactt ggaccgaatc aacagtcgtc
    23401 tataaaaatc gggattgcaa ctggtattat cttagggaga ttactcgctg aagagattta
    23461 ttttgtaaat gtatcgacgt ggagaaaata ctggaaattt agctataaag accgctcgaa
    23521 aaaatccatg aagaaacagg caatcaatgc agtagctgcg gaatttaata agcaagtgaa
    23581 ggatgacgaa gctgacgcga tactgattgg gtcttacttt actaatcttg gaaaggattt
    23641 tggcgactta gaaagtcaca aaaattgaga gaataaagtg acatataaag tggaggtaat
    23701 gaaatggaaa ttgtaaaaga tggagttaag tttattgcca gtatgataat tgttctggca
    23761 gctacatttg gctgtggata tctgttttac cgtgcaggat acgaacaggc gaaaaaggaa
    23821 gttcaaccag ttaccatcta taccgtcgat aatgtaggtg gtgtaatggt aggagaaatt
    23881 acggataaag aaattataga gggacggtac acggtcacgg ctcatgccta cggtaagttt
    23941 ctagtaacaa aagaacagta caaggcgata aaagttggcg ataaaatacc tgactatttg
    24001 aagaaaagag gtacaaaatg attgagttaa cacaaaaaca ggctgattat gttgagtttg
    24061 tcagaaaaac tattgtagat ccagatatga tggaattcgc ggtaaataca caactgatta
    24121 gctatgcttt acttgttgga tattgcattg ttgatgaaga ggtggccaaa tgaaacctag
    24181 aaagtatccg tattcaggaa agataagaat tataaaaaaa gaattaccaa ggtttgtaag
    24241 attgggagat tttgctttta atagcaacct agttaaacat attgataaaa tcagacaagt
    24301 aaaaccaaat gaaacgctaa ttcgtttcaa aatccctaag ttgtttatga catatgaaga
    24361 agaaactttt aaagtaagac ttgagattga taaagtcgta aaaatattga accaatacta
    24421 aacaaaaaaa gccagctcac agctgaccat tggttaataa ttcgataaat ctattatacc
    24481 aaaaaggagt taggaagtga gcaaagctaa ggcaatttta aaagacttac gcaatttaga
    24541 tttatatatc gctagtttaa ttagacgtca ggaaaagatt gagacctcat tgctttctag
    24601 ccctaaatgg tcgtccgata aggttaatgg tggtataaaa cgtaagcaag atgatgttta
    24661 cgtagagttg attgcaactg ccgaagatat cgagaagaag actgccgaag ctataagaaa
    24721 acaaagagag cttcagaacc tgattgatag ccttgaaaat acagacagtc aaacaatttt
    24781 aagcatggtc tatattgata agatgactag atggcaagtg attgatgagc taaattgcag
    24841 cgaaagcacc tatttcagac tgttaagagt tgcaactaag gaattaaata atttgacagt
    24901 aaatgacagc gattgacagt gaataacagt gcatgacagt tttaaagtga taatatagta
    24961 ttatcaagaa atgagggaca ggtaagaaaa tacccccctc ttttaaattt agaaaggccc
    25021 cctatgtctc aattaagggc agataaaaaa ggtactcaca gggtagcatt tgaaaagaat
    25081 aagcgaaagc tgttaaagac taccaacctc tgtggtatct gtggtaagcc agtcgataag
    25141 acactgaagt atcctcaccc gcttagcgca gcaatagatc acatagttcc tattgcaaaa
    25201 ggtggacatc cgtcagcgct agagaactta caacttacac attggcaatg taataggcag
    25261 aagtctgaca agttgttcgc taaccaagca agcaacgagc caaagacaat aggaaataga
    25321 aaccttcctc aaagtcgaga ctggtcatct tttacattaa aaaagtgaat ttgtgcaaat
    25381 tattgattta tgctaaaact ggtcagaagc taaacggggg gtatggccct ccccggtcgg
    25441 ccggccgagc ttcacgccgt cactgtacat tttttctcac gttaggattt agaaaatttt
    25501 ggaggttgaa tttcattgaa aaagaaatgc ttaatttgca aaaaaaactt ccaagcaaaa
    25561 accaatagaa ctttatattg ctctgaagaa tgccgtaaga aaggcaatcg tgagaaacaa
    25621 cgtaaattga tgaaacaaaa acgggctgaa cagaggaaag aaaaaaagaa agtcctaaat
    25681 cctaacacag atgtgacaga aaagcctaaa aaaatacgta atttagcgca gcactataaa
    25741 aaactaaaaa aggaaatttt ggcaaatgaa tctgaatttg gttttactgg aataacactt
    25801 attgaaggaa tagatgtaca tgaagaaaac tttgtagatt tagtcatgca aaaaataaag
    25861 gagcagaaat gaattatatg ggtatgggct atcttcgtag gaagttagct ctttttaaaa
    25921 ctggagttga taaaagatat cgttattatg ccatggatga cagagacgac acacgaagta
    25981 ttgtcatgcc aaataatgtg cgtgaaatgt acaggtctgt gttagaatgg accgctaaag
    26041 gggttgatag ccttgcggac cgtattattt tcagggagtt taccaacgat gattttaatg
    26101 cttgggaaat ttttaaagcg aataaccctg atatcttttt tgatacagcc atacagtcag
    26161 cattaattgc atcttgttgc tttgtgtaca tcatgccagg agcggaagac ggcttaccta
    26221 aaatgcaagt tatcgaagct agtaaagcga cggggatact tgacccaact acatttttat
    26281 taacagaggg ttatgcaatt ttagagtctg actcaaacgg taatcctacg ttagaggcct
    26341 atttcacaga caaagacatc tggtattatc caaaaaaagg gaaaccatat aatattaaaa
    26401 atccaacagg tcaccccttg cttgtaccta tcattcacag accagacgca gttagaccat
    26461 ttggtcgcag tcgcattacc aaggctggaa tgtatcatca aaaggcagcg aagagaacgc
    26521 ttgagagagc agaggttacg gctgagtttt actcattccc acaaaaatat gttttgggaa
    26581 tggatccaga cgctgaaccg atggaaaagt ggcgtgctac ggtgtcaacg ttactcgaaa
    26641 tctcaaaaga cgaggatggc gacaagccaa cagttgggca attcacaaca gcaagcatgg
    26701 cccctttcat ggaacacttg aaaatgtatg cttcgctatt tgctggtggt tccggtctca
    26761 cttttgatga ccttggtttt ccatctgaca ccccatcgtc tgttgagtca ataaaagcgg
    26821 cacatgagaa tttgagagca gcaggacgca aagctcaacg ttctttttct tctggatttc
    26881 taaatgtggc gtatattgct gtttgtttaa gagatgaatt tccttatctt cgtaatcaat
    26941 tcatggatac agtaattaaa tgggagcctc tctttgaagc tgatgcaaat atgctaactt
    27001 tagtagggga tggagctatc aaacttaatc aagctatccc tggtttcatg gatgcagatg
    27061 ttatccgtga tttaacggga gtaaaagggg ctgataaacc tatacctgct atcacggagg
    27121 taacaactga tggttgatga tgtcttacct aagctactaa aatctgttcg acaagatttt
    27181 gaaaagtatt ttggcgaaag tgatgttgta accaaggctt ttgcagaatt gcaagctaaa
    27241 aaagtgacct ataaaacagt caatgagttt gctattgaag tcggaagact tttatctttg
    27301 gctctgacag gttctgttag ctcggataaa ttaccagacg gtaaaatgta ttacaatatc
    27361 gctaagcgtc tcttagatga gactatggga cggaattaca aattgatttc aggttatgct
    27421 ggtgatgttc agcggatttt aaatgagaat gctcagattg gtctaaaggt gcaacgtcca
    27481 ccgctaaatc gagacaagat taacgggatg gtaaatcgtt tggatagcga gaatacattt
    27541 gatgatgtaa aatggctgtt tggtgaaccg attgttaatt tttcgcagtc cattgtggat
    27601 gataccatca aggcaaatgc ggatttacaa tataaaacag gtatgacgcc acaggttgtc
    27661 agaacagaaa gtggcaactg ttgtgaatgg tgtcgtgagg ttgttggcac ttatagttat
    27721 ccaaaagtcc ctaaggacgt atggagaaga catcagcggt gtcgatgtac gcttgactat
    27781 gacccgaaga atggaaaagt tcagagtgct tggagtaaaa tctggcgaaa gaaagaaaaa
    27841 actcaagaat ctatagaaag ggttgaaaaa tttaaggaaa gtgctctagt agaatctatc
    27901 aaaaatgata tcgctaagtt agatatgaca aaggttggtc cgagtgatat aattgatata
    27961 gggaaacgta tcaattatca ctttagagtt tcagaacata taggagataa agagaaatta
    28021 aaagaaattt tctcaaattt tcgtgaaatc ggtggagaaa tacctaaaaa tacttgggca
    28081 aaaggttcat ctaaacttgt taaagaccag ctacaagagg cttttcaaaa ttatccaact
    28141 gagtgggcag ctgttccgga cggtattggt aaaaaactaa aagctataaa aaggaagcgc
    28201 ggttacttcg atggatatga tgaagattta gttattgcta caaatggaac aagaaaaaca
    28261 acaccttacc atgagatagg acatatgatt gaactggtta atcctgattt agtaagatta
    28321 gagaaagcct gggtagataa aagaactgct aatgaagctg aggttcgctt gaaagatatt
    28381 tttccaagtt caaattatgg tattggggaa gttactaaga aagatgactt tatatcacca
    28441 tatattggta aatactacag cgatgcagct gaagttttca ctatgggatt acaaggtatt
    28501 tttgttcctg aagaacgatt tgctaagtcc tttgacaaaa aaacatggaa atatgactac
    28561 aagacaatca atgacgaccc tgaatttttg aattttatta ttggattatt tgtgaaagtg
    28621 tgataaatat ggaaccaaaa ttacatcggc aactgcgtca aaaatatgac gacgctgaaa
    28681 aacaatatct tgaaaagttt ggagaagact cgcttgatag agtatttttt tgggagccag
    28741 acgtttactt tgatgagtgg aaaaaggttc taccagatgc aacactggaa ttaaacaaag
    28801 ctattaatag cggggtggcg attgatccag atccagaaaa cgcaatatat taagcaccta
    28861 gagcaatctg gtgcttttct tatgcccaaa aaggagaaaa gcatgaataa aatatcataa
    28921 aatgtcgaaa tgacttggga aaacaaagac gaatttcaac aaatcatgaa taaagtcaat
    28981 gaaacaaaag aagcttacga aaaagcctta gaagctgcgg aaaattttgt ccctaaaatg
    29041 tcgtgtgcaa caaagttaaa taaaggagaa ggtaatgaat aaacgtatca agaaaaaacg
    29101 taaattggaa acagctatta tgctattgat tgcagaaaat gccttgcagg ctgaagcaat
    29161 taaaaatcaa aacaaagaaa tcatggagtt gaaatcaatt gttcagcgga acgctctggc
    29221 aacaaacgaa gagttagcga ctgttaaagc tgctacttta gataaccaat cagttatcaa
    29281 ggcaatcggt gacacggttg actacatcaa gaaaaactac aaacgtaagt gggggaagtg
    29341 atatgaaata tcgtaagaaa ccggtcgtag ttgaagcaat tcaatttacg ggtacaaact
    29401 atgaaaaaat caaagagttt attggtcaaa ataccttatg ttcgactttg agtattgtaa
    29461 tccccactct tgaaggcgac tacatcatca aaggcatcgc tggtgaattt tatccatgta
    29521 aacctgatgt ttttgaacag acttatgaat caacttaaac caaagtcgta gcaatacggc
    29581 tttttattgt gccctgtcgc atggctaaaa actaggcagt acgattgaaa ggaataagta
    29641 tggttactaa gacgaaaaca aagcttggca atcagcgacc tactcaatcg gtaaatttac
    29701 attttgctaa atctctagcg catgaagcta ttaattacta caaaaaaaca gggctaagct
    29761 gctatccatg gcaagtaaat atgcttatcc caattatggc catagatgaa aatggtctgt
    29821 gggttcatca aaagtatggg tatgctatcc cacggcgtaa cggtaagacg gaagtagtct
    29881 atattgttga gctgtgggct ttgcataaag gtttaaaaat cttgcataca gctcatcgaa
    29941 ttagcacatc tcatgcatca ttcgaaaagg taaaaaaata ccttgagatg tcaggttatg
    30001 ttgatggaga agactttata tcaaataaag ccaagggtca agagcgtata gagttcaaag
    30061 ccagcggcgc tgttatccag ttccgaacta ggacatcaaa cggtggactt ggtgagggat
    30121 ttgacttact tatcattgac gaggcacaag aatacacatc tgagcaagaa tcagcattga
    30181 agtacacagt tactgatagt gataatccaa tgactattat gtgtggaacg ccgccaacga
    30241 tggtatctac tggtacagta tttgaagcat atcggaaaga ttgcttaaaa ggcaataagc
    30301 gttattctgg ttgggctgaa tggtcagttc ctgagatggt taagattaac gatgtatctt
    30361 cctggtatat ttccaaccca tctatgggat tccacctcaa cgagaggaaa atcgaagctg
    30421 aattaggtga agatgagatt gatcacaaca tccaacgctt aggttattgg ccatccttta
    30481 accaaaaatc agttatatcc gaaaaagaat gggcaaaact caaagttgag caagtgccag
    30541 aactcaaaag caagcttttt gtcggtatca agtttggtca agatggcaac aacgtatcac
    30601 tatcaattgc agcaagaaca tcagaaaata aggtatttgt cgagactatt gactgtttat
    30661 cagttaggaa tggtactcaa tggattatta attttctgaa atcagctgac attgctaagg
    30721 ttgtaattga tggcgccagc ggccaagaat tacttgctca ggagatgaaa gagcaaggtc
    30781 taaagaaacc agaattgcct aaagttgctg aaattatcac agctaacatg atgtgggagc
    30841 aggggatcat gcaggaaacc atttgtcata gtgatcagcc atctttgaca gcagtagtca
    30901 caaactgtga aaagaggcaa attggctcta atggtggttt tgggtataag tcgctttatg
    30961 atgatagaga cattagctta atggacagtg cattgcttgc gcactggatt tgttacacaa
    31021 cgaagccaaa aagaaagcaa agaaccagct gttaaaaaac gacatccgaa agggtgtttt
    31081 tttactgcta aaaaatctac cgaactgccg ggaaagcagg agaaaggacg ttaatatgtc
    31141 agaatttaaa gttattgaaa cacaagaaga gttggacacg attgtgaaag ctcgcattgc
    31201 tcgagaacgt gagaaatatc aagattacga ccaactgaaa actcgtgttg aagaactaga
    31261 aaccgaaaac agcagcttac aaactgcttt gaatgatgct aaatcaaaca ctgatagcta
    31321 tacggaagag attagcaccc tgaagaatca aattgccgat tatgagacgg caaatttacg
    31381 gacaaaggta gcgttacagt atggcttacc aattgattta gctgatcgtt tgcaaggaga
    31441 tgatgaagat ggactcaaag tagatgcaga acgcttagca tcctttatta agccatccca
    31501 accacaaccg ccagcaaaat caaacgaacc aaatatcgat agtaatgcag acgcaaatta
    31561 cagagcgtta gtgcaaggat taagtacaga agattagaag attaattaaa ggagaaaaaa
    31621 tatgggaaca gaaacatcaa aagcaagctt atttgacaaa catttagtat cagatcttat
    31681 caataaagtt aaggggcata gctcactagc taaactatct agccaaaaac ctattccgtt
    31741 taacggatct aaagaattta cgtttacatt agattctgat attgatgtgg ttgctgaaaa
    31801 cggtaaaaaa acacacggtg gcttatcgct agagcctgtt actatcgtac caatcaaggt
    31861 tgagtatggt gctcgtcttt ctgatgaatt tttatatgca acagaagaag aaaagattga
    31921 tattttgaaa gcttttaacg aagggtttgc gaaaaaactc gctcgtggta ttgacctaat
    31981 ggcgatgcat ggtatcaatc cacgtacaaa aaaagcgtct gacgttatcg gcacgaatca
    32041 ctttgatagt aaagtgacgc aagtggttaa atttacagag agcgaagacg ctgatgcaaa
    32101 tatcgaagca gctgttaatc taattcaggg ggctgaaggt gtagtgacag ggcttgcgat
    32161 ggatacagag ttttcaacag cactggcga
//
LOCUS       DAXMQE010000018        31344 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.018, whole genome shotgun sequence.
ACCESSION   DAXMQE010000018 DAXMQE010000000
VERSION     DAXMQE010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31344)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31344)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31344
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.018"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            569..652
                     /locus_tag="ACF4ZO_001044"
     CDS             569..652
                     /locus_tag="ACF4ZO_001044"
                     /inference="COORDINATES: protein motif:HMM:NF024729.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HFD5486596.1"
                     /translation="MDYCNNKRIKIKLKGLSPLQYKTKSFT"
     gene            complement(690..1613)
                     /locus_tag="ACF4ZO_001045"
     CDS             complement(690..1613)
                     /locus_tag="ACF4ZO_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFD5486597.1"
                     /translation="MSEKLVEVKDLEISFGEGKKKFVAVKNANFFIKKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSSGQILYDGKVINGRKSKSEANELIRKIQMIFQDPAASLNE
                     RATVDYIISEGLYNFNLFKTEEERKEKIKNMMAEVGLLSEHLTRYPHEFSGGQRQRIG
                     IARALVMNPEFVIADEPISALDVSVRAQVLNLLKRMQAEKGLTYLFIAHDLSVVRFIS
                     DRIAVIHKGVIVEVAETEELFNNPIHPYTQSLLSAVPIPDPILERQKELVVYHPDQHD
                     YTLDKPSMVEIKPNHFVWANQAEIEKYQKEL"
     gene            complement(1606..2676)
                     /locus_tag="ACF4ZO_001046"
     CDS             complement(1606..2676)
                     /locus_tag="ACF4ZO_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD5486598.1"
                     /translation="MTKENNVILTAKDVVVEFDVRDRVLTAIRNVSLELVEGEVLAFV
                     GESGSGKSVLTKTFTGMLESNGRIANGSIVYRGQELTDLKTNKEWAKIRGSKIATIFQ
                     DPMTSLSPIKTIGSQITEVIIKHQKVSHAKAKEMALDYMNKVGIPNAKKRFEDYPFEY
                     SGGMRQRIVIAIALACRPDILICDEPTTALDVTIQAQIVELLKSLQREYHFTIIFITH
                     DLGVVASIADKVAVMYAGEIVEFGTVEEIFYDPRHPYTWSLLSSLPQLADESGELYAI
                     PGTPPSLYSPIIGDAFALRSEYAMVLDFEKAPPAINVSETHWAKTWLLHPEAPKVQKP
                     EVIQDLHQKILRKMSQQEEGNV"
     gene            complement(2685..3611)
                     /gene="oppC"
                     /locus_tag="ACF4ZO_001047"
     CDS             complement(2685..3611)
                     /gene="oppC"
                     /locus_tag="ACF4ZO_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009569326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter permease OppC"
                     /protein_id="HFD5486599.1"
                     /translation="MESIDKSKFRFVERDSEASEVIDTPAYSYWKSVFRQFFSKKSTV
                     FMLVILVTVLMMSFIYPMFANYDFNDVSNINDFSKRYIWPNAEYWFGTDKNGQSLFDG
                     VWYGARNSILISVIATLINITIGVVLGAIWGVSKAFDKVMIEIYNIISNIPSMLIIIV
                     LTYSLGAGFWNLILAFCITGWIGVAYSIRVQILRYRDLEYNLASQTLGTPMYKIAVKN
                     LLPQLVSVIMTMLSQMLPVYVSSEAFLSFFGIGLPTTTPSLGRLIANYSSNLTTNAYL
                     FWIPLVTLILVSLPLYIVGQNLADASDPRSHR"
     gene            complement(3611..5113)
                     /locus_tag="ACF4ZO_001048"
     CDS             complement(3611..5113)
                     /locus_tag="ACF4ZO_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD5486600.1"
                     /translation="MKKYILNRIMRSLVSVVLVTALTYTIVYTLVPTSLIFKQDPNYN
                     KMTTTPDKKVAYENLTFQRMGYVNYFSSKELKDNASKVDSSVTTEATSANKAIYEKYI
                     DSLGNGWQLKRFPTSKQFYAIRNIPIYERVWNFFSNLVVIDHPWKIQDKDNPKLARYI
                     RLEKDKSVGWSLVGSGTKHKYLLYTNGKFPYLHQNFVTLNLGTSYPTYSNIPVLQVIS
                     QGQGRTALQDVTFPSGVTKKSSVDIYSRSYKNPKSLDDITKVNYGKGDSYTKTINNYV
                     DPSMIHNSFVIGFFGVMFSYIVGLPLGLFMARFKNTYFDRFSTATMTFMLALPSIAVI
                     YVVRFLGGMVGLPDSFPMLGASDPKSYILPALILGILNIPTTVIWFRRYLVDLQASDW
                     VRFARSKGLSESEIYRGHLFKNAMVPIVSGVPASIILAIGGATLTETVFAFPGMGKML
                     IDSIKSANNSMIVGLTFIFTVLSIVSLLLGDIVMTLVDPRIKLSTKKGGK"
     gene            complement(5178..7148)
                     /locus_tag="ACF4ZO_001049"
     CDS             complement(5178..7148)
                     /locus_tag="ACF4ZO_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HFD5486601.1"
                     /translation="MKKSKWLAAVSVAILSVSALAACGNKNASGGSEATKTYKYVFVN
                     DPKSLDYILTNGGGTTDVITQMVDGLLENDEYGNLVPSLAKDWKVSKDGLTYTYTLRD
                     GVSWYTADGEEYAPVTAEDFVTGLKHAVDDKSDALYVVEDSIKNLKAYQNGEVDFKEV
                     GVKALDDKTVQYTLNKPESYWNSKTTYSVLFPVNAKFLKSKGKDFGTTDPSSILVNGA
                     YFLSAFTSKSSMEFHKNENYWDAKNVGIESVKLTYSDGSDPGSFYKNFDKGEFSVARL
                     YPNDPTYKSAKKNYADNITYGMLSGDIRHLTWNLNRTSFKNTKKDPAQQDAGKKALNN
                     KDFRQAIQFAFDRASFQAQTAGQDAKTKALRNMLVPPTFVTIGESDFGSEVEKEMAKL
                     GDEWKDVNLADAQDGFYNPEKAKAEFAKAKEALTAEGVTFPVQLDYPVDQANAATVQE
                     AQSFKQSVEASLGKENVIVNVLETETSTHEAQGFYAETPEQQDYDIISSWWGPDYQDP
                     RTYLDIMSPVGGGSVIQKLGIKAGQNKDVVAAAGLDTYQTLLDEAAAITDDNDARYKA
                     YAKAQAYLTDNAVDIPVVALGGTPRVTKAVPFSGGFSWAGSKGPLAYKGMKLQDKPVT
                     AKQYEKAKEKWMKAKAKSNAKYAEKLADHVEK"
     gene            7480..8712
                     /gene="pbp3"
                     /locus_tag="ACF4ZO_001050"
     CDS             7480..8712
                     /gene="pbp3"
                     /locus_tag="ACF4ZO_001050"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase PBP3"
                     /protein_id="HFD5486602.1"
                     /translation="MIKRLISLVVIALFFAASTVSGEEYSVTAKHAIAVDLESGKVLY
                     EKDAKEVVPVASVSKLLTTYMVYKEVSKGKLNWDSPVTISNYPYELTTNYTISNVPLD
                     KRKYTVKELLSALVVNNANSPAIALAEKIGGTEPKFVDKMKKQLRQWGISDAKVVNST
                     GLTNHFLGANTYPNTEPDDENCFCATDLAIIARHLLLEFPEVLKLSSKSSTIFDGQTI
                     YSYNYMLKGMPCYREGVDGLFVGYSKKAGASFVATSVENQMRVITVVLNADQSHEDDL
                     AIFKTTNQLLQYLLINFQKVQLIENNKPVKTLSVLDSPEKTVKLVAQNSLFFIKPIHT
                     KTKNTVHITKKSSTMIAPLSKGQVLGRATLQDKHLIGQGYLDTPPSINLILQKNISKS
                     FFLKVWWNRFVRYVNTSL"
     gene            8880..10061
                     /locus_tag="ACF4ZO_001051"
     CDS             8880..10061
                     /locus_tag="ACF4ZO_001051"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="HFD5486603.1"
                     /translation="MTKRIILTIFTFICFSMMPLVHAEDVIDITRQAGYTVSEVNRPK
                     SSIVVDANSSDILWQDNIDIPRDPASMSKMFTLYILFEELAKGKITMDTTITATPTDQ
                     AIANIYEISNNNIVAGVAYPIRDLITMTAVPSSNAATVMIANYLSNNDASAFIDRINA
                     TAKQLGMTNTHFSNASGAAAQAFQGYYNPTKYDLSASNITTARDLSKLLYAFLKKYPE
                     IISFTNKSVVHTMVGTPYEEEFHTYNHSLPDNQFGMKGVDGLKTGSSPSAAFNAMITA
                     KRGKTRLITIVMGVGDWSDQNGEFYRHPFVNALTEKGFKDSKTLSKKARQKLEKLVPQ
                     TKKETSPKQQHFKATKKQSYLERVEDFMNYNHTLLLICLAIFIITILLLSLVVFAMGR
                     Q"
     gene            complement(10213..11631)
                     /gene="sufB"
                     /locus_tag="ACF4ZO_001052"
     CDS             complement(10213..11631)
                     /gene="sufB"
                     /locus_tag="ACF4ZO_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017769002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HFD5486604.1"
                     /translation="MSDINEKVELKPIDLGDYQFGFHDDVEPIYSTGKGLSEAVVREL
                     SAAKNEPEWMLEFRLKSLETFNKMPMQTWGADLSDINFDDIIYYQKASDKPARSWDDV
                     PEKIKETFDRIGIPEAERAYLAGASAQYESEVVYHNMKGEFEKLGIIFTDTDSALKEY
                     PDLFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENTGQ
                     FERTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVY
                     NLVTKRARALTDATVEWIDGNLGAKTTMKYPSVYLDGPGARGTMLSIAFANAGQHQDT
                     GAKMIHNAPHTSSSIVSKSIAKSGGKVDYRGQVTFNKQSKKSVSHIECDTILMDDISK
                     SDTIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKE
                     LPMEYAVELNRLISYEMEGSVG"
     gene            complement(11624..12103)
                     /gene="sufU"
                     /locus_tag="ACF4ZO_001053"
     CDS             complement(11624..12103)
                     /gene="sufU"
                     /locus_tag="ACF4ZO_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly sulfur transfer protein
                     SufU"
                     /protein_id="HFD5486605.1"
                     /translation="MALSKLNHLYMAVVADHSKRPHHHGQLDGVEAVQLNNPTCGDVI
                     SLTVKFDEDKIEDIAFAGNGCTISTASSSMMTDAVIGKSKEEALALADIFSEMVQGQE
                     NPAQKELGEAELLAGVAKFPQRIKCSTLAWNALKEAIKRSANAQHLTDQNVKEGKNV"
     gene            complement(12090..13316)
                     /locus_tag="ACF4ZO_001054"
     CDS             complement(12090..13316)
                     /locus_tag="ACF4ZO_001054"
                     /EC_number="2.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0031071 - cysteine desulfurase activity
                     [Evidence IEA];
                     GO_process: GO:0006534 - cysteine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HFD5486606.1"
                     /translation="MLDAKDIKQDFQILNQQVNDEPLVYLDNAATTQKPALVLEALQS
                     YYQEDNANVHRGVHTLAERATHKYEASRQQVADFIHAKSSKEVLFTRGTTTSLNWVAR
                     FAEQVLTPEDEVLISIMEHHANIIPWQQACQKTGARLVYVYLKDGQLDMDDLTNKLTT
                     KTRFVSLVHVSNVLGCINPIKEIAKLAHAKGAYLVVDGAQSVPHLAIDVQDLDCDFFA
                     FSAHKMLGPTGLGVLYGKEELLNQVEPLEFGGEMIDFVYEQEATWKELPWKFEAGTPH
                     IAGAIGLSAAISYLQRLGMADIHAHEAELIAYVLPKLEAIEGLTIYGPSQSSARSGLI
                     SFNLDDLHPHDLATALDYEGVAVRAGHHCAQPLLSYLGVPATVRASFYIYNTKADCDR
                     LVEAILKAKEFFNGTL"
     gene            complement(13347..14609)
                     /gene="sufD"
                     /locus_tag="ACF4ZO_001055"
     CDS             complement(13347..14609)
                     /gene="sufD"
                     /locus_tag="ACF4ZO_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HFD5486607.1"
                     /translation="MTKEKLVAFSQAHAEPAWLQERRLEALKAIPELELPTIERVKFH
                     RWNLGDGTLTENESLASVPDFIAIGDNPKLVQVGTQTVLEQLPMALIDKGVVFSDFYT
                     ALEEIPEVIEAHFGQALAFDEDKLAAYHTAYFNSAAVLYVPDHLEITTPIEAIFLQDS
                     DSDVPFNKHVLVIAGKESKFTYLERFESIGNATQKTSANISVEVIAQAGSQIKFSGID
                     RLGPSVTTYISRRGRLEKDANIDWALAVMNEGNVIADFDSDLIGQGSQADLKVVAASS
                     GRQVQGIDTRVTNYGQRTAGHILQHGVILERGTLTFNGIGHILKGAKGADAQQESRIL
                     MLSDQARADANPILLIDENEVTAGHAASIGQVDPEDMYYLMSRGLDQETAERLVIRGF
                     LGAVIAEIPIPSVRQEIIKVLDEKLLNR"
     gene            complement(14704..15474)
                     /gene="sufC"
                     /locus_tag="ACF4ZO_001056"
     CDS             complement(14704..15474)
                     /gene="sufC"
                     /locus_tag="ACF4ZO_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HFD5486608.1"
                     /translation="MSILEINNLHVSIEGKEILKGVNLTLKTGEVAAIMGPNGTGKST
                     LSAAIMGNPNYEVTQGQILLDGVNILDLEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAMNAGKADEDKISVRDFITKLDEKMALLGMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPKFALLDEIDSGLDIDALKVVSKGVNEMRGKDFGAMIITHYQRLLNYITPDLVHV
                     MMDGRIVLSGDAALATRLEKEGYAGIAQDLGIEYKEES"
     gene            complement(15596..16765)
                     /locus_tag="ACF4ZO_001057"
     CDS             complement(15596..16765)
                     /locus_tag="ACF4ZO_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HFD5486609.1"
                     /translation="MFSFTIDYVLVLIGALLMPLFLTPLVRFLAFRVGAVDNPNARRV
                     NKVPMPTSGGLAIFMSFLVASLGLIPTASKGAMFFGQTYFSYILPVVIGATVITLTGF
                     LDDLYELSPKLKMFGILIGAMIVWAFTDFKFDSFKIPFGGPLLVFGPFLTLFLTVLWI
                     VSITNAINLIDGLDGLVSGVSIISLMTMAIVSYFFLPQKDFFLTLTILVLIAAIAGFF
                     PYNYHPAMIYLGDTGALFIGFMIGVLSLQGLKNSTAVAVVTPVIILGVPIMDTIVAII
                     RRSLSGQKFYEPDKMHLHHRLLSMGFTHRGAVLVVYGITMLFSLISLLLNVSSRIGGV
                     LLMLGLLFGLEVFIEGLEIWGEKRTPLFNLLKFIGNSDYRQAMLLKWKEKKDLKH"
     gene            complement(16772..17533)
                     /gene="mecA"
                     /locus_tag="ACF4ZO_001058"
     CDS             complement(16772..17533)
                     /gene="mecA"
                     /locus_tag="ACF4ZO_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HFD5486610.1"
                     /translation="MEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYSV
                     MDELDLPDNFKDSGMLSFRVTPRKDRLDVFVTKSEINKDINLEDLAEFGDMSQMTPED
                     FFKSLEQSMREKGDVKAHEKLEQIEEIMEDVVEATLANQSEAADPSTNHESEPLDYVH
                     YVLDFSTITEAVAFAKTIDFSIEASELYKGSNCYHMTILLDVQQQPSYFANVMYARLI
                     EHANPGSKTRAYLQEHGLQLMLDGAVEQLQKIELG"
     gene            complement(17679..18518)
                     /locus_tag="ACF4ZO_001059"
     CDS             complement(17679..18518)
                     /locus_tag="ACF4ZO_001059"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0050380 - undecaprenyl-diphosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0016311 - dephosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HFD5486611.1"
                     /translation="MLIIELLKAIFFGIIEGITEWLPVSSTGHLILVQEFIRLNQDKA
                     FIEMFNIVIQLGAIIAVMLIYFERLNPFQPGKTAREVQLTWQLWLKVVIACIPSILIA
                     VPLDNWFEAHFYFMVPIAIALIVYGIAFIWIEKRNAQQEPAVTELARMSYKTAFFIGC
                     FQVLSIVPGTSRSGATILGAIILGTSRTVAADFTFFLAIPTMFGYSGLKAVKFLLDGH
                     HLDFAQVLILLVASLTAFVVSLLAIRFLTDYVKKHDFTIFGKYRIVLGSLLLIYSFFK
                     FVF"
     gene            complement(18584..20509)
                     /locus_tag="ACF4ZO_001060"
     CDS             complement(18584..20509)
                     /locus_tag="ACF4ZO_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HFD5486612.1"
                     /translation="MKKILMTLVFCFSLLGIRIKAADVDYSITNYEGQLLLSKENTAR
                     FEQKVTYQFDTSYNGQYISLGRAGHLPAGFAIDQKPKVEVYQNGQQVPVSQEFSDLGD
                     GYRLKLYNAGQAGDKVDVKVTWQLHHLLTAYQDVAELNWTPISDWDKTLEKVSLTVTT
                     PTDIQDSNLWAHRGYYQKKPQVLKEGNSRYQINAKNVSGQLELHAYWDKKALLGKEPV
                     DVSTSKKNKIVALETKISRRRTLLQLLFGKVIPLVEVGFLLWQLIQFTRLKKQFNRYH
                     LANHTDHSYEVPEDLSPLVLTQAIYGQSFAYLSPTASESQKLLIPKGVTFEALVQATL
                     LDLIDQKVLLLTKEEGKAYLEISQLDRVTDEEAAFLDMAFGNKVTLPVDQLFSQYHYD
                     ADTIKQLKKTYKGKKLEQEVRQSSEQVIKAMKKASAAITNNVLETIKKLNLPDTYRQM
                     TQAEKRKSNSVQGLGCLLLILNSGLLIYLAIKESGLALIYLALMVLTMCLGFYISLKL
                     DQYKKLGIETPEGGVRLHQWQSFKNMIRDIDKFEDVAIEGLVVWNRVLVYATLFGYAK
                     KVERYLKVHRIALPEVYQAVRPGELSMVMYATTPTFVSSLSSATTSSNFSVSSGGGIS
                     GGGGFSGGGGGGGGGAF"
     gene            20707..22275
                     /locus_tag="ACF4ZO_001061"
     CDS             20707..22275
                     /locus_tag="ACF4ZO_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HFD5486613.1"
                     /translation="MKKLILSCLVALALLFGGMSRAQANQYLRVGMEAAYAPFNWTQD
                     DASNGAVPIEGTSQYANGYDVQVAKKIAKAMNKELLVVKTSWTGLIPALTSGKIDMIT
                     AGMSPTKERRNEISFSNSYYTSQPVLVVTANGKYAEATSLKDFSGAKVTAQQGVWHVN
                     LLTQLKGAKLQTPMGDFSQMRQALTSGVIDAYISERPEAMTAEAADSRLKMITLKKGF
                     AVAESDAAIAVGMKKNDDRMATVNQVLEGFSQTDRMALMDDMVTKQPVEKKAEDAKAS
                     FLGQMWAIFKGNWKQFLRGTGMTLLISMVGTITGLFIGLLIGIFRTAPKAKHKVAALG
                     QKLFGWLLTIYIEIFRGTPMIVQSMVIYYGTAQAFGISIDRTLAAIFIVSINTGAYMS
                     EIVRGGIFAVDKGQFEAATALGFTHGQTMRKIVLPQVVRNILPATGNEFVINIKDTSV
                     LNVISVVELYFSGNTVATQTYQYFQTFTIIAIIYFVLTFTVTRILRHIERRFDADTYT
                     TGANQMQIAEVSNV"
     gene            22268..23008
                     /locus_tag="ACF4ZO_001062"
     CDS             22268..23008
                     /locus_tag="ACF4ZO_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003063284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HFD5486614.1"
                     /translation="MSNSIIEIKNLKKSYGSNEVLKDISLSVNKGEVISIIGSSGSGK
                     STLLRSINLLEEPSAGQILFHGEDVLAEHYNLTHYREKLGMVFQSFNLFENLNVLENA
                     IVAQTTVLKRDRAQAEQIAKENLNAVGMTEQYWQAKPKQLSGGQKQRVAIARALSVNP
                     EAMLFDEPTSALDPEMVGEVLKTMQDLAKSGLTMIIVTHEMEFARDVSDRIIFMDKGL
                     IAEEGSPQQIFENPTQDRTKEFLQRFLK"
     gene            23150..23266
                     /locus_tag="ACF4ZO_001063"
     CDS             23150..23266
                     /locus_tag="ACF4ZO_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HFD5486615.1"
                     /translation="MAEKTDLSSAYRRLKSPNIKTRKRALKIIHEYKRYGKK"
     gene            complement(23491..24501)
                     /gene="gap"
                     /locus_tag="ACF4ZO_001064"
     CDS             complement(23491..24501)
                     /gene="gap"
                     /locus_tag="ACF4ZO_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HFD5486616.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNIEGVEVTRINDLTDPNMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGNFIKVSAERDPENIDWATDGVEIVLEATGFFAK
                     KEAAEKHLHANGAKKVVITAPGGNDVKTVVFNTNHDILDGTETVISGASCTTNCLAPM
                     AKALHDAFGIQKGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAI
                     GLVIPELNGKLDGAAQRVPVPTGSVTELVVTLDKNVSVDEINAAMKAASNDSFGYTED
                     PIVSSDIVGVSYGSLFDATQTKVMEVDGSQLVKVVSWYDNEMSYTAQLVRTLEYFAKI
                     AK"
     gene            complement(24849..26927)
                     /gene="fusA"
                     /locus_tag="ACF4ZO_001065"
     CDS             complement(24849..26927)
                     /gene="fusA"
                     /locus_tag="ACF4ZO_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HFD5486617.1"
                     /translation="MAREFSLAKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWDGHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVQTLHDRLQANAH
                     PIQLPIGAEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPEEYLEQAQEYREKLIEAV
                     AETDEDLMMKYLEGEEITNDELIAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVIA
                     YLPSPLDIPAIKGVNPDTDAEEERPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     NSGSYVMNTSKGKRERIGRILQMHANSRQEIETVYAGDIAAAVGLKDTTTGDSLTDEK
                     AKVILESIEVPEPVIQLMVEPKSKADQDKMGVALQKLAEEDPTFRVETNVETGETVIA
                     GMGELHLDVLVDRMKREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLIESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLALKEAAKSAQPAILEPMMLVTITAPEDNLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSATQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGE"
     gene            complement(27412..27882)
                     /gene="rpsG"
                     /locus_tag="ACF4ZO_001066"
     CDS             complement(27412..27882)
                     /gene="rpsG"
                     /locus_tag="ACF4ZO_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HFD5486618.1"
                     /translation="MSRKNQAPKREVLPDPLYNSKIVTRLINRVMLDGKRGTAATIVY
                     DAFSAIKEATGNDALEVFETAMDNIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVNASRARGEHTMKDRLAKEIMDAANNTGASVKKREDTHKMAEANRAFAHFRW"
     gene            complement(27903..28316)
                     /gene="rpsL"
                     /locus_tag="ACF4ZO_001067"
     CDS             complement(27903..28316)
                     /gene="rpsL"
                     /locus_tag="ACF4ZO_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HFD5486619.1"
                     /translation="MPTINQLVRKPRKSKIEKSDSPALNIGYNSHKKVQTKMAAPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLIRGGRVKD
                     LPGVRYHIVRGALDTAGVADRKQGRSKYGAKRPKG"
     gene            complement(28524..31145)
                     /locus_tag="ACF4ZO_001068"
     CDS             complement(28524..31145)
                     /locus_tag="ACF4ZO_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SEC10/PgrA surface exclusion domain-containing
                     protein"
                     /protein_id="HFD5486620.1"
                     /translation="MDLEQTKPNQVKQKIALTSTIALLSASVGVSHQVKADDRASGET
                     KASNTHDDSLPKPETIQEAKATIDAVEKTLSQQKAELTELATALTKTTAEINHLKEQQ
                     DNEQKALTSAQEIYTNTLASSEETLLAQGAEHQRELTATETELHNAQVDQHSKETALS
                     EQKASISAETTRAQDLVEQVKTSEQNIAKLNAMISNPDAITKAAQTANDNTKALSSEL
                     EKAKADLENQKAKVKKQLTEELAAQKAALAEKEAELSRLKSSAPSTQDSIVGNNTMKA
                     PQGYPLEELKKLEASGYIGSASYNNYYKEHADQIIAKASPGNQLNQYQDIPADRNRFV
                     DPDNLTPEVQNELAQFAAHMINSVRRQLGLPPVTVTAGSQEFARLLSTSYKKTHGNTR
                     PSFVYGQPGVSGHYGVGPHDKTIIEDSAGASGLIRNDDNMYENIGAFNDVHTVNGIKR
                     GIYDSIKYMLFTDHLHGNTYGHAINFLRVDKRNPNAPVYLGFSTSNVGSLNEHFVMFP
                     ESNIANHQRFNKTPIKAVGSTKDYAQRVGTVSDTIAAIKGKVSSLENRLSAIHQEADI
                     MAAQAKVSQLEGKLASTLKQSDSLNLQVRQLNDTKGSLRTELLAAKAKQAQLEATRDQ
                     SLAKLASLKAALHQTEALAEQAAARVTALVAKKAHLQYLRDFKLNPNRLQVIRERIDN
                     TKQDLAKTTSSLLNAQEALAALQAKQSSLEATIATTEHQLTLLKTLANEKEYRHLDED
                     IATVPDLQVAPPLTGVKPLSYSKIDTTPLVQEMVKETKQLLEASARLAAENTSLVAEA
                     LVGQTSEMVASNAIVSKITSSITQPSSKTSYGSGSSTTSNLISDVDESTQRALKAGVV
                     MLAAVGLTGFRFRKESR"
     gene            complement(31136..>31344)
                     /locus_tag="ACF4ZO_001069"
     CDS             complement(31136..>31344)
                     /locus_tag="ACF4ZO_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HFD5486621.1"
                     /translation="ITGMISLLTEFDSTLVGVAVFAENAQSEREQMTFKSLLKVSEID
                     VKNNNVVVEVGNIFDKWKKEREWT"
BASE COUNT         9415 a         6477 c         5768 g         9684 t
ORIGIN      
        1 ttgcccgcgt tgtaaaatga agtgcaacaa aaaagaggaa aagccttgaa ctacacccca
       61 aacgttagac aaaaaaatct aacgttcggg gtatttttta tgaaattaag tgatgaaggt
      121 acgaaataga catcgttaag aaagaaaaaa atacctacta tccaccagag ataaagcagg
      181 aaataatgga taacgttttg atagaaggcc cgccacaata ccaagtatca cttgtttatg
      241 gcttgttaca tgcaggaact ctcccaagtt gaatagcaca atataagaaa aacagttata
      301 ctgttgagaa aacaagagca agaccatcac aaacaggacg taaaccaaaa gaaacctgaa
      361 gaaatgacta aattagagcg gcttcaagaa gaaaatgaat atctcagaac tgaggttgct
      421 tacttaaaaa aaccgaggaa ctccgtttga aagaagcatc tctgcaaaga aggagacaaa
      481 aaaccattat aaaaaatgga caaagacgag ctctgattag attttctttt aagaacggct
      541 gtattgactc gttctaccta ctattatcat cgattattgc aacaataaac gtatcaaaat
      601 aaaactaaaa ggacttagtc ctctacaata caaaactaaa tcctttactt aaaatagagt
      661 agccaacttt tggagtcagt gcatctcttt tacaattctt tttgatattt ttcaatttct
      721 gcttggtttg cccaaacaaa gtgatttggt ttgatttcaa ccattgatgg cttatctaat
      781 gtataatcat gctggtctgg atgatagaca acaagttctt tttgacgctc taaaattgga
      841 tctgggatag gcacggctga taacaaagat tgggtgtagg gatgaattgg gttattaaac
      901 agttcttctg tttctgcaac ttctacaata acccctttat ggataaccgc aatacgatct
      961 gaaataaagc gaacgactga aagatcatgg gcaatgaaga gataagtcaa acctttttcg
     1021 gcttgcatcc gtttgagaag gtttaaaacc tgtgcgcgaa cggaaacgtc caaagctgaa
     1081 atcggttcat cagcaataac gaattcaggg ttcattacta gggctctagc gataccgatc
     1141 cgctgacgtt gacctcctga aaattcatgt gggtagcgcg tcaaatgctc tgatagcaaa
     1201 ccaacttcgg ccatcatgtt cttaattttt tctttacgtt cttcctctgt tttaaacaga
     1261 ttaaagttat aaagaccttc tgaaatgata tagtcaacgg ttgctcgttc attcaaacta
     1321 gcagcgggat cttggaaaat catttgaatt ttacgaatga gctcattggc ttctgatttt
     1381 gattttctgc cattaattac tttcccatcg tataaaattt gacctgaact agtatcgttc
     1441 aaaccaataa tagcacgacc aattgttgtt ttaccactcc cagattctcc aactaaagaa
     1501 aaggtttctc cttttttaat aaagaaatta gcatttttaa ctgcaacaaa ttttttcttt
     1561 ccttctccga aggaaatttc taggtctttt acttcgacta atttctcaga catttccttc
     1621 ctcctgttgt gacattttcc ttaagatttt ttgatgcaaa tcttgaatga cttctggttt
     1681 ttgaactttt ggagcctctg ggtgtaaaag ccatgttttg gcccaatgag tctcagatac
     1741 gttaatcgcc ggaggtgctt tttcaaagtc taaaaccata gcatattctg agcgaagtgc
     1801 aaaggcatct ccgataattg gtgaataaag tgatggaggc gttcctggaa tagcgtaaag
     1861 ttcaccagat tcatctgcca actgcggtaa gctagacagc aaactccatg tataggggtg
     1921 tcttggatca tagaaaatct cttcgactgt tccaaattca acaatttctc ctgcatacat
     1981 gacagccact ttatctgcaa tgcttgccac aacacctaaa tcgtgcgtaa taaagataat
     2041 ggtgaaatga tattctcgtt gaagcgactt caataactca acgatttgag cttgaatagt
     2101 cacatcaagg gctgttgttg gctcatcaca gataagaata tctgggcgac aagctaaagc
     2161 aatagcgata acaatacgtt gacgcattcc tcctgaatac tcaaatgggt aatcttcaaa
     2221 gcgttttttg gcatttggga tacccacttt attcatgtaa tcaagggcca tttctttagc
     2281 tttggcatga cttacttttt ggtgcttaat aatcacttct gtgatttggc taccaatagt
     2341 tttaatggga ctaagactgg tcattgggtc ttggaaaatc gttgcgattt ttgagccgcg
     2401 aatctttgcc cactctttat ttgtttttaa atctgtcaat tcttgcccac gatagacaat
     2461 tgaaccatta gcaatgcgtc cattagactc caacatccct gtaaaggtct ttgttaaaac
     2521 agatttacct gagcctgatt cccctacaaa agcaaggact tctccttcaa caagttccag
     2581 tgagacgtta cggatagctg ttaaaacacg atcacgcaca tcaaattcta ccaccacatc
     2641 tttggcagtt aagattacat tattttcttt tgtcatttta actcctatct atgtgaacgt
     2701 gggtcactgg catcagccaa gttttgtccg acaatgtata gtggtaacga tactaaaatc
     2761 aatgttacta agggaatcca aaagaggtag gcatttgttg ttaagttgct tgaataatta
     2821 gcaatcaaac gtcctaaact tggagtggtg gttggtaaac caatcccaaa gaaggataag
     2881 aaggcctcag aagatacata aactggtagc atttgtgaca acatagtcat gataactgaa
     2941 accaattgag gcagcaggtt cttaacagca atcttgtaca ttggtgttcc caaagtttga
     3001 ctagcaaggt tgtattctaa atcacggtaa cgcaagattt gaacacggat ggagtaggcg
     3061 acaccaatcc atccagtgat acagaaagct agaatcaaat tccaaaatcc tgcacctaat
     3121 gaataggtca aaacaatgat aataagcata gaagggatat ttgagataat gttataaatt
     3181 tcaatcataa ctttatcaaa tgctttagaa actccccata tggctcctaa cactacccca
     3241 atggtgatat taattagtgt cgctataact gagattaaaa tagaattacg tgccccatac
     3301 caaacaccat caaacagaga ttgcccattt ttgtcggttc caaaccagta ctctgcattt
     3361 ggccaaatat aacgctttga aaagtcattg atattactaa cgtcattaaa gtcgtagttg
     3421 gcaaacattg gataaataaa gctcatcatc aagactgtca ctaaaatcac gagcataaag
     3481 actgtagatt ttttagaaaa aaactgacga aacactgatt tccagtaaga ataagcaggg
     3541 gtatcaatca cttcggaggc ttcactatcg cgctcaacaa atcgaaattt agatttatca
     3601 atcgattcca ttacttacct cctttttttg ttgacaattt aatacgtgga tcgacaaggg
     3661 tcatgacaat atctcctagt aaaagtgaaa caattgacaa gacagtgaag ataaaggtta
     3721 atccaacaat catagaattg ttagcagatt taatagaatc aattaacatt ttacccatac
     3781 ccgggaaggc aaagacagtc tctgttaatg ttgcaccacc aatagcaagg ataatacttg
     3841 caggaacccc tgacacaatt gggaccatgg catttttgaa gagatgccct ctgtaaattt
     3901 cagattctga taatcctttt gaacgcgcaa aacgtaccca atcgctggcc tgaaggtcaa
     3961 caagatagcg acggaaccag ataaccgtag ttggaatatt taaaattcct aaaataaggg
     4021 ctggtaaaat ataagattta ggatcagatg cccccagcat tgggaaacta tctggtaaac
     4081 caaccatgcc acctaggaag cgaacaacat agataacagc aatacttggt aaagcaagca
     4141 tgaaggtcat ggtcgctgtt gagaaacggt caaaataggt atttttaaac cgagccataa
     4201 ataaaccaag aggcaaacca acgatatagg aaaacataac accaaaaaaa ccaattacaa
     4261 aagaattgtg aatcattgat gggtcgacat aattattgat ggttttagtg taggaatctc
     4321 ccttaccata gtttaccttg gtgatatcat ccaatgattt tggatttttg tagctacggc
     4381 tatagatatc cactgacgat ttcttagtga cacctgatgg gaaggtcaca tcttgaagag
     4441 ctgttcgtcc ttgcccttgt gaaataacct gaagaacagg aatattgctg tatgttggat
     4501 aagatgttcc taagtttagg gtaacaaagt tttggtgaag ataaggaaat tttccgttag
     4561 tatagaggag atacttatgt tttgtccccg aaccaacaag tgaccagcca actgatttat
     4621 ctttttctag acgaatatac ctagctaatt ttggattatc tttatcctga atcttccaag
     4681 ggtgatcaat aacaactaga tttgagaaaa agttccaaac acgttcgtaa ataggaatat
     4741 tgcgaattgc ataaaactgt ttgctagtgg ggaagcgttt tagctgccag ccattgccaa
     4801 gagaatcaat atacttctca tagatagctt tgttagcact agttgcttct gtcgttacac
     4861 tactatctac tttagaagca ttatctttta attctttgct tgaaaaataa ttgacataac
     4921 ccatacgttg aaaagttaga ttttcatacg ctactttttt atctggtgtt gttgtcattt
     4981 tattataatt agggtcttgt ttaaagataa ggctggtagg tactagagta tatacgatgg
     5041 tgtatgttaa agccgttacc aaaactaccg acactaacga tcgcatgata cggtttaaaa
     5101 tatatttttt catagttgtc ctcaatagtt caaaagaact ccctcacata aacgagaaag
     5161 ttcttttgaa catcgtttta tttttcaacg tgatcagcta acttctcagc atattttgca
     5221 tttgacttag cctttgcttt catccatttt tcttttgctt tttcgtattg ttttgctgtg
     5281 acaggtttgt cttgaagttt cattccttta tatgctagag gacctttaga ccctgcccaa
     5341 gagaagcccc cgctaaatgg aacggcttta gtaactcgtg gagtgccacc caatgccaca
     5401 actggaatat ctacggcatt atctgtaagg taggcttgtg cttttgcgta agctttatag
     5461 cgcgcatcgt tgtcgtctgt aattgctgct gcttcatcaa gaagagtttg gtaggtatca
     5521 aggcctgcag ctgccacaac atccttattt tgacctgctt tgattccaag tttttggata
     5581 acagatccac cacctactgg actcatgatg tcaaggtagg tccgtggatc ttgatagtct
     5641 ggtccccacc atgatgaaat gatatcgtag tcttgttgtt ctggggtctc agcatagaag
     5701 ccttgggctt cgtgagttga tgtttctgtt tcaagaacat tgacaatgac attttcttta
     5761 ccaagagatg cttcaacaga ttgtttgaaa gactgggctt cctgaacagt tgctgcgttt
     5821 gcttggtcaa cagggtaatc taattgaact gggaaggtta caccttcagc tgtcaaagct
     5881 tctttggctt ttgcaaactc agcttttgct ttttcaggat tatagaaacc atcttgagca
     5941 tcagctaagt taacgtcttt ccattcatca ccaagttttg ccatttcctt ttcaacttct
     6001 gaaccaaaat cactttctcc aatggtcaca aatgttggtg ggacaagcat gttacgtaag
     6061 gcttttgttt tagcatcttg acctgcagtt tgggcttgga atgacgctcg gtcaaaagca
     6121 aactgaatag cttgacgaaa atccttgttg ttaagagctt tcttaccggc atcttgttgt
     6181 gcagggtctt tcttagtgtt tttgaaagaa gtacggttca aattccatgt taaatgacgg
     6241 atatctccac tcaacattcc gtaagtaatg ttatcagcat agtttttctt agctgatttg
     6301 taggtagggt catttgggta aagtcgtgca acgctgaact cacccttgtc aaagttcttg
     6361 tagaacgaac ctgggtctga accatctgag taagtcaatt taacagattc tatcccaaca
     6421 ttcttagcat cccagtagtt ttcattttta tggaattcca tagatgattt tgaggtgaag
     6481 gcgctcaaga agtaagcacc attaacaagg attgatgatg gatcggttgt accaaaatct
     6541 ttaccttttg acttcaaaaa tttcgcatta actgggaaaa gcacactata agttgttttt
     6601 gaattccagt agctttcagg cttgttcaaa gtatactgaa cagttttatc gtcaagggct
     6661 ttgacaccaa cttctttaaa atctacttca ccattttggt aagcctttaa gttttttatt
     6721 gaatcttcaa caacgtaaag agcatctgat ttatcgtcaa ccgcgtgctt caaaccagtc
     6781 acaaaatctt ctgctgttac tggggcatat tcttcaccat cagccgtata ccaagagaca
     6841 ccatcgcgaa gagtataagt ataagtcaga ccgtcttttg aaaccttcca atctttagca
     6901 agtgatggta ctaaattacc atactcatcg ttttccaaaa gaccatcaac catttgtgtt
     6961 atcacatcag tcgttccacc gccattagtc aaaatataat ccaatgattt tggatcgtta
     7021 acaaaaacgt acttgtaggt ttttgtagct tctgagccac ctgaagcatt tttattacca
     7081 caagctgcca aagcggatac tgacaagatc gcaacactta cagctgccaa ccatttactt
     7141 ttcttcatac aaagtcaccc ctaaacttta tttttcattt tttggcaatt gctaaatgaa
     7201 attggttaat tgaagacatt atatcataaa actttcttaa agaaaataat gaaatgaaaa
     7261 attatctgaa tatttcgtag aattttcttt attttataca tttatctata tgaaagcgtt
     7321 atactcctct tttaatgagg tttcaattag tttaataaag attgtcattc tctcatggta
     7381 gctttttatt atatcattac tcttgtgagg taagtcatta ccttagacaa aaatatggta
     7441 taattaaaaa aataatactt gagtaaggat aatctataaa tgatcaaacg attaatttcc
     7501 ctagtggtca tcgccttatt ttttgcagca agcactgtta gcggtgaaga gtattcggta
     7561 actgctaagc atgcgattgc cgttgacctt gaaagtggca aagttttata cgagaaagat
     7621 gctaaagaag ttgtcccagt cgcctcagtc agtaagctct tgacaaccta tatggtttac
     7681 aaagaagttt ctaagggcaa gctaaattgg gatagtcctg taactatttc taactaccct
     7741 tatgaactca ctacaaacta tactattagt aacgttcctc ttgataagag aaaatatacc
     7801 gttaaagaac tcttaagtgc gttagttgtt aataacgcca atagccccgc tattgcttta
     7861 gctgaaaaaa taggcggaac cgaacccaaa tttgttgaca aaatgaaaaa acaattaaga
     7921 caatggggca tttccgatgc aaaggtcgtc aattcaactg gcttaactaa ccatttttta
     7981 ggagctaata cttatcctaa tacagaacca gatgatgaaa attgtttttg cgccactgat
     8041 ttagctatta ttgccaggca tctcttatta gaatttccag aagtactgaa attatctagc
     8101 aaatcctcca ctatttttga tggacaaacc atttacagtt ataattacat gcttaaaggc
     8161 atgccttgtt atcgagaagg cgtggatggt ctttttgttg gttattctaa aaaagccggt
     8221 gcttcttttg tagctactag tgtcgaaaat caaatgaggg ttattacagt agttttaaat
     8281 gctgatcaaa gccacgagga tgatttagct atatttaaaa caaccaatca attgttgcag
     8341 taccttttaa ttaattttca aaaagtccag ttaattgaaa ataataaacc agtaaaaacg
     8401 ttatctgtct tagacagtcc tgaaaaaact gtcaaacttg tagcccaaaa tagtttattt
     8461 tttatcaaac caatacatac aaagaccaaa aataccgtcc atattactaa gaaatcatcc
     8521 acaatgatcg cacctctatc aaagggacaa gtcttaggta gagcaaccct tcaagacaaa
     8581 catcttattg gacaaggtta tctggatact cctccttcta tcaatcttat ccttcaaaaa
     8641 aacatttcta aaagtttctt tttaaaggtc tggtggaacc gttttgtgag gtatgtcaat
     8701 acctctttat agaataacac aatgcttttt gtatgacatt gactgacaga gtacttctgc
     8761 agtctttttc atttttattt aagcaaacta ggctaatcct aacaattttt caaaaaaact
     8821 tcacattgta ttagcaaagt gatatactga aaatgcatta catttaaagg agtcggaaat
     8881 tgaccaaaag aattatacta actattttta cctttatttg cttttcgatg atgcctcttg
     8941 tccacgccga agatgtcata gatattacaa ggcaagcagg ctacacagtt agtgaggtta
     9001 atcgaccaaa atcttctatt gtcgttgatg caaatagttc agatattctt tggcaagata
     9061 atattgatat tcctagggat cctgctagta tgtctaaaat gtttacgctt tacattttat
     9121 ttgaagagct cgctaaggga aaaattacga tggacactac tattacggca actccaaccg
     9181 atcaagctat cgctaacatt tatgagatta gcaataataa tatcgtcgct ggagtagctt
     9241 atcctattcg tgatcttatt actatgacag ctgtgccttc atcaaatgca gcaactgtta
     9301 tgattgccaa ttatttatca aacaatgatg cttctgcgtt tatcgatcgt attaatgcca
     9361 cagccaaaca attaggcatg actaacactc atttttcaaa cgctagtggt gcagcagcac
     9421 aagcttttca aggttattat aatcccacta aatatgattt atctgcttca aatattacga
     9481 ccgctcgaga tttgtccaag ttactctatg ccttcttaaa aaaataccct gaaattatct
     9541 cctttacaaa taaatctgtt gtgcacacta tggtaggaac gccatatgaa gaagaatttc
     9601 acacctataa ccactctctc ccagataatc aatttggtat gaaaggagtt gatggattaa
     9661 aaacaggttc tagtcccagt gctgctttta acgccatgat aactgccaaa agaggcaaaa
     9721 ctcgactcat tactattgtc atgggggtcg gagattggtc agatcaaaac ggagagtttt
     9781 atagacatcc tttcgttaat gccttgactg agaaagggtt taaagatagt aagaccttgt
     9841 ccaaaaaagc acgccaaaaa ctcgaaaaat tagtgccaca aaccaaaaaa gaaacatcac
     9901 ctaaacagca gcacttcaaa gccactaaaa agcaatcgta cttggaaaga gtcgaagatt
     9961 ttatgaatta caaccatact ctcttgctta tttgcttagc tatctttata attactatcc
    10021 ttttactaag cctcgttgtc tttgcaatgg gacgccaata atgaattatc aaaaacctct
    10081 gtcaaagcac agaggttttt gatatgttat cttacgtgtt taaggcaact aaaaactaac
    10141 cacttggggt tagtactaca actcataaaa tcctatctca aagatctttc agatggataa
    10201 gagaaaatgc aattaaccga cagaaccttc catctcatag gaaatcaatc gattgagttc
    10261 gaccgcgtat tccattggca attctttggt aaaaggctcc acaaatccca tgacaatcat
    10321 ctctgtggct tcgctttctg ataagccacg gctcatgaga tagtagagtt gttcttcaga
    10381 aatcttagac actttggctt catgttctaa cgccacctgt gaattatgaa tttcgttaaa
    10441 tgggatcgta tctgatttag aaatatcgtc catcaaaata gtatcacatt caatatggga
    10501 aacggatttt ttagattgct tgttaaaggt cacttggcca cgataatcta ctttaccacc
    10561 agacttggca attgattttg acacaattga tgatgatgta tgtggagcat tgtgaatcat
    10621 tttagcccct gtatcttggt gttgacctgc gttagcaaag gcaatagaca gcatggtgcc
    10681 acgcgcacct ggcccatcaa gataaacaga agggtacttc atggtggttt tagctcctag
    10741 attgccatca atccattcca ctgttgcatc cgtaagggcg cgtgcacgtt ttgtcactag
    10801 attatacaca ttgtctgacc agttttgaat ggtggtataa cgcatgtatg caccgtcaag
    10861 cgcaaagatt tcaacgatag cagcatgtag gctgttactt gaataagtgg gagctgtaca
    10921 tccttcaaca taatgaacac ttgctccttc atcaacaata atcaatgtcc gctcaaactg
    10981 accagtattt tcattgttaa tgcggaaata agtttgcaaa gggatatcta ccttgacccc
    11041 tttaggaaca taaataaagg taccaccaga ccaaactgct gaattgaggg ctgctaattt
    11101 gttgtctgtt ggcggaacca gtttggcaaa gtattgtttg aacaaatcag gatattcttt
    11161 gagggcggaa tcggtatctg taaagataat ccctagcttt tcaaattcac ccttcatgtt
    11221 atggtaaacc acttctgact catactgagc tgatgcccca gcaagataag cacgttctgc
    11281 ttctggaatt ccaatacgat caaaggtttc ttttattttt tctggaacat catcccaaga
    11341 acgagctggc ttatcagatg ctttttgata gtaaatgata tcatcaaagt taatatctga
    11401 taagtctgct ccccaggttt gcatcggcat tttattaaag gtttccaagg attttaaacg
    11461 aaactccaac atccactcag gttcattttt ggcagctgat agttcgcgaa ccactgcctc
    11521 actcaatcct tttcctgtag aataaatggg ctctacatca tcgtgaaatc caaattggta
    11581 gtctcctaag tcaattggct ttagctctac tttctcattt atatcagaca tttttccctt
    11641 cctttacatt ttggtccgtg aggtgctgag cattggcact tcgtttaatg gcttccttga
    11701 gagcattcca agctagggta gagcatttga tacgctgtgg aaattttgca actcctgcca
    11761 acaattctgc ttcacctagc tctttttgag caggattttc ctgtccttgt accatctctg
    11821 aaaaaatatc agctaacgcg agtgcttctt ctttactttt accaataaca gcatctgtca
    11881 tcatgcttga tgaagctgtg gaaatggtac agccgttgcc tgcaaaagca atatcttcaa
    11941 ttttatcttc gtcaaactta acggtcaaag aaatcacatc accacaagtc ggattattca
    12001 gttgaacagc ctctacgcca tctagttgcc catgatgatg tggacgtttc gaatggtccg
    12061 ctaccacagc catgtataga tggttcagtt tagagagtgc cattgaaaaa ctcctttgct
    12121 tttagaattg cttcgactaa acggtcacaa tctgccttgg tgttatagat ataaaaactt
    12181 gctctaacag ttgctggtac acctaaataa ctaagaagag gttgggcgca gtggtgccct
    12241 gctcttactg caacaccttc atagtccaag gctgttgcca agtcatgagg atgcaaatca
    12301 tccagattaa aagaaatcag accagatctt gcactagact ggcttggtcc atatatggta
    12361 agcccctcaa tagcttctaa tttcggcaaa acataggcta ttagttctgc ttcatgcgca
    12421 tgtatatcag ccatgcctag tctctgaagg taagaaatgg ctgcgcttag cccaatagca
    12481 ccagctatgt gaggtgttcc tgcttcaaac ttccagggca attctttcca agtggcctct
    12541 tgttcgtaaa caaaatcaat catttctccg ccaaattcaa gaggctccac ttgattcaaa
    12601 agctcttctt tgccgtaaag aacacccaaa cctgttggcc ccaacatctt atgagctgaa
    12661 aaagcaaaga aatcacaatc caagtcttga acatcaatag ccaaatgtgg aaccgactgg
    12721 gcaccgtcaa caacaaggta ggctccttta gcatgtgcca gcttggcaat ttctttaatg
    12781 ggattgatgc aaccaagaac attggagaca tgtactaggc taacaaaacg tgtttttgtc
    12841 gtcaatttgt ttgtcaaatc gtccatgtca agttggccat cttttaaata aacatagact
    12901 aaccttgctc ctgttttttg acaggcttgt tgccaaggaa tgatattggc atgatgctcc
    12961 ataatcgaaa tcaacacctc atcttctggc gtcaagacct gctctgcaaa ccgagcaacc
    13021 caattcaaac tggttgttgt tcctctggta aagagcactt ccttgcttga tttagcatga
    13081 ataaagtcag caacctgctg gcgactggcc tcatatttgt gcgttgcacg ttcagccaag
    13141 gtatgaactc ctcggtgaac attagcatta tcttcttgat aataggattg caaagcctca
    13201 agaacaagcg ccggtttttg tgtggtggcg gcattatcca aataaacaag gggttcatca
    13261 ttgacttgtt gatttaagat ttgaaagtct tgtttgatgt cttttgcgtc tagcaatact
    13321 aacctctttc tttttggcag taggtcttaa cgattaagca atttctcatc taaaacctta
    13381 ataatctctt ggcggactga tggaatagga atttcagcga taaccgctcc taggaatcct
    13441 ctaataacca atcgttctgc tgtttcttga tccagtcctc gactcatcaa gtaatacata
    13501 tcttcagggt caacctgacc gatagaagct gcatgacctg ctgttacttc attttcatca
    13561 attaagagga ttggattggc atcggctctt gcttggtcag aaagcatcaa aatacggctt
    13621 tcttgttgag catcagctcc cttagcgcct tttagaatat gaccaatccc gttaaacgtt
    13681 aaggtgccac gttccaaaat cacaccatgc tgtaaaatat gaccggccgt acgttgacca
    13741 tagttggtca cgcgcgtgtc aataccttgt acctgacgac cacttgaggc tgcaacaact
    13801 ttcaaatcag cttgtgagcc ctgaccaatc aaatcactgt caaaatcagc aatgacattg
    13861 ccttcattca tcacagctaa ggcccaatca atgttggcat ccttctctaa acgtcctcga
    13921 cggctaatat aggttgtcac tgaaggacct aagcggtcga tacccgagaa tttaatctgg
    13981 ctgcctgctt gagcaatcac ttctacactg atattagcgc tggtcttttg agtggcattg
    14041 ccaatagatt caaaacgctc taaataggtg aacttacttt cttttcctgc aatcactaga
    14101 acatgcttgt taaaaggaac gtcactgtca ctatcttgta agaaaatagc ttcaatagga
    14161 gttgtgattt ccaagtgatc aggaacgtag agcacggctg cgctattaaa ataagcagtg
    14221 tggtaggcag ctagtttgtc ttcatcaaaa gctaatgcct gaccaaaatg agcttcaatt
    14281 acttctggga tttcctcaag cgccgtataa aaatcactga aaacaactcc cttgtcaatt
    14341 aacgccattg gtaactgttc taagactgtt tgcgtgccta cctgaacaag ctttgggtta
    14401 tctccaatag ctataaaatc tggaacacta gctagacttt cattttctgt taaggtacca
    14461 tctcctagat tccaacggtg aaatttaacc ctttcgatgg ttggtaactc taattctggt
    14521 atggctttca gtgcctctaa acgccgttct tgcagccaag caggctcagc gtgggcttgc
    14581 gaaaaagcta ctagtttttc ttttgtcatc tgtcaatcct ttgtctctgg tttttaaatt
    14641 ggctggatat atagaacatc acctagcttt ttgtagaaag ctaaagtaat tgtctccaaa
    14701 aacttaactt tcttccttat actcgattcc cagatcctgt gcaatacctg cgtagccttc
    14761 tttttcaaga cgagtagcca aggcagcatc accagataag acaatacgac catccatcat
    14821 aacatgaact aggtctgggg taatgtaatt caacaaacgt tgatagtggg tgataatcat
    14881 agctccaaag tctttcccac gcatctcatt aaccccttta gagactactt ttagggcatc
    14941 aatatcaaga ccagaatcaa tttcatctag caaagcaaat ttaggctcta acatgagcaa
    15001 ttgaagaatt tcattgcgtt ttttctcccc accagaaaaa ccttcattga ggtaacgctc
    15061 tgccatctct tctttcatac ctaacaaagc cattttctca tcaagtttgg tgataaaatc
    15121 tcgcacggaa atcttatcct catctgcctt accggcattc attgctgcac gcataaattc
    15181 agcgttggta atccctggaa tttctgaagg gtattgcatg gcgagaaaaa gtcccagtct
    15241 cgcacgctca tcaacttcta gatcgagaat attgaccccg tcaagcaaaa tttgcccttg
    15301 ggtcacttcg tagttaggat ttcccataat agctgctgaa agggtagact ttcctgtccc
    15361 atttggcccc ataatggcag ctacttcccc agttttaaga gttaggttaa cccctttcaa
    15421 aatctcttta ccttctattg aaacatgtaa attattaatc tcaagaattg acatgataca
    15481 ccccttattt tctctgtcat ctataccatc tcaagaaaag acagtgtcat ttgcactgct
    15541 ttttttataa tggtcactgc atctattata gcaaaaaaag ccttactcgg cttttttagt
    15601 gtttcaaatc cttcttttct ttccatttca gaagcattgc ttgacgataa tcactattac
    15661 caataaactt taacaagtta aacaaaggcg ttcgcttttc accccagatc tccaatcctt
    15721 caataaaaac ttctaaacca aataaaagtc caagcatcaa gaggacgcca ccaattcgac
    15781 tagaaacatt taaaagtaaa gaaataaggg aaaaaagcat ggtaatacca taaactacta
    15841 agacagctcc tcgatgagta aagcccattg ataagagtcg atgatgcagg tgcatcttat
    15901 ccggctcgta gaatttttga cctgataaac tacgtcgaat aatagccacg atggtatcca
    15961 taatgggtac accaagaata ataacaggtg tcaccacagc cacagccgtt gaatttttca
    16021 atccttgaag agacaaaacc cctatcataa agccaataaa gagggctcct gtgtcaccca
    16081 aataaatcat agctggatgg taattataag gaaaaaatcc tgcaatagca gcaatcaaga
    16141 ccaaaatggt taacgtcaaa aagaaatcct tttgaggtaa aaagaaataa gatacaatag
    16201 ccatggtcat taaactaata atagagaccc cactaaccaa accatccaaa ccgtcaatca
    16261 agttaatagc attagtgatg gaaacaatcc acaggactgt taagaataag gttaagaaag
    16321 gaccaaaaac taacaacggc cctccaaaag gaattttgaa gctatcaaat ttaaagtcgg
    16381 taaaagccca gacaatcatt gcaccaatta gaataccaaa catctttaat ttaggactta
    16441 actcatataa atcatctaaa aaaccagtaa gggtaattac tgtagcacca atcacgacag
    16501 gtaaaatata actgaagtag gtctgaccaa aaaacatggc gcctttagaa gcagtcggaa
    16561 taagtcccaa acttgctact aaaaaagaca taaaaatagc taatccacca ctggttggca
    16621 tcggaacctt attgacccgt ctggcattgg gattgtctac tgcacccaca cgaaaagcta
    16681 aaaagcgaac aagaggggtt aagaataagg gcattaacaa agcccctatc agaacaagga
    16741 cataatctat tgtgaatgaa aacatactat tttatcccaa ctcaatcttt tgtaattgct
    16801 caacagcacc atcaagcatc aattgtaagc catgctcttg taaataagct cttgtttttg
    16861 atccagggtt tgcatgctca atcaatctcg catacatgac attcgcaaaa taagatggtt
    16921 gttgctgaac atctaataaa atagtcatat ggtagcagtt gctcccctta tataactctg
    16981 aagcttctat cgaaaaatca atcgttttag caaaagccac tgcctctgta atcgttgaaa
    17041 aatccaatac ataatggaca tagtctaaag gttctgactc atgattagtt gatggatcag
    17101 ccgcctcaga ctgattagct agagtggctt caacaacatc ttccattatc tcttcaattt
    17161 gttccaattt ttcatgagct ttgacatctc ccttttcacg catggattgc tccaagctct
    17221 tgaaaaaatc ttccggagtc atttgggaca tatcaccaaa ctctgctaaa tcttcaagat
    17281 taatatcttt atttatctca gatttggtaa caaaaacatc tagacggtcc ttgcgtggag
    17341 tcactcgaaa actaagcata ccactatctt taaaattatc tggaagatcg agttcgtcca
    17401 tcacagaata gaaaaactct tctgtttttt cttgaggaat caagaaatct ttcaactcca
    17461 ttcctctttc ttctaaatcg tccatactaa ttgttatttt tagcgttgtc tcgctaattt
    17521 gtttcatttc cattctcaat acctcgcacg cgtagtcatt ttattatact agaaatgctg
    17581 taatttcgca atttatgact aactcctcgt ctacaaaagg aaatttaaaa agcgacagtc
    17641 cccaaggtct gtcgcaacat cctaaacgat atgtaagttt aaaaaacaaa tttaaagaag
    17701 ctataaataa gtaaaaggct tcctaacaca atacggtatt tcccaaaaat ggtgaaatcg
    17761 tgtttcttaa cataatctgt caagaaccta atcgccaata aactaaccac aaaagcggtc
    17821 aagctagcca ctaaaagaat aaggacttgt gcaaaatcaa ggtgatggcc atcaagtaaa
    17881 aatttcacag cctttaatcc actatatcca aacatggtag gaatggccaa aaagaaggtg
    17941 aaatcagcgg ccactgttcg actagttcct aaaataatag ctcctaagat ggtagcccct
    18001 gatcgactag taccaggcac aatacttaag acttgaaaac aaccaatgaa gaaagctgtt
    18061 ttgtaagaca ttctagctaa ctcagtgacg gcaggttctt gttgagcatt tcgtttttca
    18121 atccagataa aggcaatccc gtagacgatt aaagcgatgg caatcggaac cataaaataa
    18181 aaatgtgctt caaaccaatt atcaagagga accgctatta aaatagaagg aatacacgca
    18241 atcaccactt ttagccataa ttgccaggta agctgtactt ctcttgctgt tttcccaggt
    18301 tgaaagggat tgagacgttc aaaataaatc aacataacag cgataatcgc ccctaattga
    18361 ataacgatat taaacatttc tataaaagcc ttatcctgat ttagtcggat aaattcctgc
    18421 accaaaatga ggtgaccagt gcttgaaact ggtaaccatt ctgtgattcc ctcaatgatg
    18481 ccaaagaaaa tggcttttag caattcgata attaacatgt tttctcctta ttaaccactc
    18541 ttattgtgat tttctaaact gtgattaatg ccaagcagct tttttaaaag gcaccgccgc
    18601 cgcctcctcc gccaccgcca gagaagccgc caccaccact aatcccgcct ccggaagaga
    18661 ctgagaaatt tgaggaagtt gtagctgaag acaagctaga cacaaaggtt ggtgtcgtag
    18721 catacattac cattgataat tcacctggtc gaacagcttg gtaaacctca ggtaaggcaa
    18781 tacgatggac tttcaaatag cgttccactt tcttagcgta accaaataag gtggcataaa
    18841 ccaaaacacg gttccaaaca accaaacctt caatagcaac atcctcaaat ttgtcaatat
    18901 ctcgtatcat gtttttaaag ctctgccatt gatgtaaccg aacacccccc tcaggtgttt
    18961 caatacccaa tttcttgtat tgatctaact tcaggctaat gtaaaagcca aggcacatcg
    19021 ttagcaccat taaagcaagg taaatgaggg ctaacccact ttctttaata gccaagtaaa
    19081 tcaataaacc actatttaga ataagcaaca aacaacctaa tccctggaca ctattgcttt
    19141 ttcgtttctc tgcctgggtc atttgacgat aagtatctgg taagtttaac tttttgatag
    19201 tttctaggac attgtttgta atagctgccg acgctttttt catcgcctta atcacctgct
    19261 cagacgattg acggacttct tgctcgagct ttttaccttt gtacgttttc tttaattgtt
    19321 taatggtatc agcatcataa tggtattgac taaacaattg atccaccggc aatgtcacct
    19381 tgtttccaaa agccatatct aagaaggcag cttcctcatc tgtcacacga tctaactgac
    19441 tgatttcaag ataagctttc ccttcttctt tcgttaataa aagcaccttt tggtcgatca
    19501 gatccaacaa ggtagcttga acaagggcct caaaggtcac tcctttaggg atcaataatt
    19561 tctggctttc tgatgctgta ggggataaat aggcaaaact ctgtccataa atcgcttgtg
    19621 tcaacacaag aggcgaaaga tcttcaggga cttcgtaact gtgatctgta tggttagcca
    19681 aatgataacg attgaattgt ttctttaatc ttgtaaactg tattaactgc caaagaagaa
    19741 aacctacctc taccagagga atgactttgc caaatagcag ctgtaacaag gtccttcgtc
    19801 tggaaatctt agtttctaac gctacaattt tattcttttt actcgttgaa acatcaactg
    19861 gctcttttcc caataatgct tttttatccc aataagcatg caattccaat tgccctgaga
    19921 cattcttggc attaatctga tagcgactgt taccttcttt taacacttga ggtttctttt
    19981 ggtaatatcc tctgtgagcc catagattag aatcctgaat atcagttggg gtagtaacgg
    20041 tcaaactcac cttttctaat gttttgtccc agtcactgat cggtgtccaa ttcagctctg
    20101 ccacgtcttg ataagctgtt aaaaggtggt gcagttgcca ggtaacctta acgtcaacct
    20161 tatcaccagc ttggccagca ttataaagtt ttaaacgata gccatctcca aggtcactaa
    20221 actcttgact aacaggtacc tgttgaccat tctgatatac ctcaacttta ggcttttggt
    20281 caatagcaaa gcccgctggc aaatgacctg cccggcccag cgaaatatac tggccgttat
    20341 aagaagtgtc aaattgatag gttacttttt gctcaaaccg agcagtattt tcttttgata
    20401 acagtaactg accttcatag ttggtgatgc tatagtctac atcagctgct tttattcgta
    20461 tccctaaaag actgaagcag aacacaagcg tcatcaaaat ttttttcatg gcaacatcct
    20521 ctttctgccc tcattttacc atattttaag gagatgacaa aacctaaacc aagtccttca
    20581 tcttattttt aatcattatt ttgaatattt ttccatattt caacctattc actgataata
    20641 tattgaaata ggatgcaaat tgctgtaaaa taggtctgaa tactattttt gaaacaggag
    20701 acctatatga aaaagctaat ccttagctgt ttggtcgcct tggcccttct gtttggagga
    20761 atgagccggg ctcaagcaaa ccaatattta agagtcggaa tggaagcagc ctatgctcct
    20821 tttaactgga ctcaagatga cgcttcaaac ggggctgtcc ctattgaggg aactagccaa
    20881 tacgccaacg gttacgatgt ccaagtcgct aaaaaaatcg ctaaagctat gaacaaagaa
    20941 cttttagtcg ttaagacctc ttggaccggt ttaattccag cattaacttc tggaaaaatc
    21001 gatatgatca ctgctggtat gagtcctacc aaagagcgta gaaacgaaat tagcttctca
    21061 aacagctact acactagcca acctgttcta gtcgtaactg ctaatggcaa atatgctgag
    21121 gcaacaagcc tcaaggattt ttctggagct aaagtaactg cccagcaagg cgtttggcat
    21181 gtcaatctct taactcaact aaaaggtgct aagttacaaa caccaatggg ggatttctct
    21241 caaatgcgac aagcccttac ttcgggtgtt atcgatgcct atatttctga acggcctgaa
    21301 gccatgactg ctgaagctgc tgatagccgt ttgaaaatga tcactcttaa aaaagggttt
    21361 gctgttgctg aatcagatgc tgctatcgct gtcggaatga aaaaaaatga cgatcgtatg
    21421 gcaactgtca accaagtgct tgaaggattt tctcaaacag atcgtatggc cctgatggat
    21481 gatatggtta ccaaacaacc cgtggaaaag aaagccgaag atgctaaagc atcatttcta
    21541 ggccaaatgt gggctatttt taaaggtaac tggaagcaat tcttacgtgg aactggaatg
    21601 acccttctga tttccatggt cggaaccatt acaggtctct ttattggatt attaatcggt
    21661 attttccgta cagctcctaa agctaagcat aaagtagctg ccttgggaca aaaactcttt
    21721 ggttggttac tcactattta tatcgaaatc ttccgtggga cacctatgat tgttcaatct
    21781 atggttatct actacggaac agcgcaagcc tttggtattt cgatcgaccg taccctagcg
    21841 gctattttta tcgtatctat caatacgggt gcctatatga gtgaaattgt tcgcggtggt
    21901 attttcgctg tcgacaaagg tcaattcgaa gcagcaactg ctcttggctt tactcacgga
    21961 caaaccatgc gtaaaatcgt gctaccacaa gttgttcgca acattttacc agcaacaggt
    22021 aatgagtttg tcatcaatat caaagatact tctgttttga atgttatctc tgttgtggaa
    22081 ctttacttct caggtaatac cgtagccaca caaacctacc aatatttcca aacctttacg
    22141 attatcgcca ttatctactt tgttcttacc ttcacggtga cacgtattct tcgtcatatt
    22201 gaacgccgtt tcgatgccga tacttacacc actggagcaa accaaatgca gattgcggag
    22261 gtctcaaatg tctaactcaa ttattgaaat caaaaacctc aaaaaatctt acggcagcaa
    22321 tgaagtactc aaagatatct ccctttctgt taacaaggga gaagtgattt ccattatcgg
    22381 ttcttctggt tctggaaaat caaccctcct gcgctcgatc aatcttttgg aagagccaag
    22441 tgccggtcaa atcctctttc atggtgaaga tgtccttgct gaacactaca acttgactca
    22501 ctaccgtgaa aaactaggca tggttttcca atcctttaac ttgtttgaaa acctaaatgt
    22561 attggaaaat gctatcgtcg ctcaaaccac cgtcctcaaa agagaccgtg cacaagccga
    22621 acaaatcgct aaagaaaacc tcaatgcggt tggtatgaca gaacaatact ggcaagccaa
    22681 accaaaacaa ttatcagggg ggcaaaaaca acgggttgcc attgccagag ccttatctgt
    22741 caatccagaa gccatgctct ttgatgaacc aacatcagct cttgatcctg aaatggttgg
    22801 tgaggtcctt aaaaccatgc aagacttggc aaaatcaggg ttgaccatga ttattgttac
    22861 ccatgaaatg gaatttgctc gtgatgtttc tgaccgtatc atcttcatgg ataagggatt
    22921 gattgctgaa gaaggaagtc ctcaacaaat tttcgagaat cctacacaag atcgtaccaa
    22981 agaattttta caacgcttct taaaataaga taaaggatcc aactatttct atgccagttg
    23041 ggtctttttt caattcaaaa agaatttgtc ataaaatact ttaccagtta actattttat
    23101 gctatactta tttttgttaa cgttaataat ttatatttag gaggataata tggcagaaaa
    23161 aactgactta tcgtcagctt acagaagact gaaaagtccc aatattaaaa ccagaaaacg
    23221 tgctctgaag attattcacg agtacaaacg ttacggtaaa aaataagatt ttacttttta
    23281 tctctccaaa tttaagtcag acaaaaaagg ctaagacacc ccttccatct tagccttttt
    23341 gtatacagtt tattaaggga actattttaa aatatctttt atgctagagt ctagaatagt
    23401 tcaaaacgtt aaaattatac atttaagata gtgtttaaag tatacgaaaa agaactcagc
    23461 ataaaccaag ctctctttcg ttataactaa ttatttagca atttttgcga agtactcaag
    23521 agtacgtaca agttgagcag tgtaagacat ttcgttgtca taccatgata caactttaac
    23581 caattgtgat ccgtcaactt ccattacttt agtttgagtt gcgtcaaaca atgaaccgta
    23641 tgatacgcct acgatatctg aagaaacgat tggatcttca gtgtaaccga agctatcgtt
    23701 tgaagcagct ttcatagcag cgttgatttc gtcaacagaa acgtttttgt caagagttac
    23761 aaccaactca gttactgatc cagttggaac aggaacacgt tgtgcagcac cgtcaagttt
    23821 accgttaagt tctgggataa caagaccgat agctttagca gcaccagttg agttaggaac
    23881 gatatttgca gcaccagcgc gtgcacgacg aagatcacca ccacggtgtg gtccgtcaag
    23941 gatcatttgg tcaccagtgt aagcgtggat tgtagtcata agaccttttt gaataccgaa
    24001 tgcatcgtga agagctttag ccataggagc taaacagttt gtagtacatg aagcacctga
    24061 gataactgtt tcagtaccgt caagaatgtc gtggttagtg ttgaaaacaa ctgttttaac
    24121 atcgtttcca ccaggagctg tgataacaac ttttttagca ccgttagcat gtaagtgttt
    24181 ttcagctgct tcttttttag caaagaaacc agttgcttca agaacgattt caaccccatc
    24241 agttgcccag tcgatgtttt ctggatcacg ttcagcagaa actttgatga agtttccgtt
    24301 tacttcaaat ccaccttctt taacttcaac tgttccatca aaacgacctt gagttgtatc
    24361 gtatttcaac aagtgtgcaa gcatatttgg atctgtaagg tcattgatac gagttacttc
    24421 aacaccttcg atgttttgaa tacggcggaa tgcaagacgt ccgatacgac cgaaaccgtt
    24481 aataccaact ttaactacca ttagtgattt cctccttatg aaaatcaaaa gaatattatt
    24541 tagagggaat gctccctacc tattgtgaaa agattaactt acagtcatct gcaacaacct
    24601 ttcaacagaa ctattatata actatttcag aaaaaatgca aataaattag ccattttcat
    24661 aaagggcagc ttctttcttc tagccttcaa aacccaccaa atataggaaa gggctttctt
    24721 ttttctatgt tctattctgt aatttatctt tttattggga aagatttcca aaacttcaaa
    24781 ctgtactata acgttctgtt atactaaaaa agaggttagg atagttatcc tcaacctctt
    24841 agtggtggtt attcaccttt gtttttctta atgatttctt cttgaactga cttaggaaca
    24901 tcttcatagt ggtcaaatac catcatgaac gtaccacgtc cttgagttgc agaacgaaga
    24961 actgttgcat aaccgaacat ttcagcaagt ggtacataag cacgaacgat ttggctgtta
    25021 ccatgtgctt ccataccatc aacgcgtcca cgacgagctg tcacgtgtcc cataacgtct
    25081 ccaagattgt cttctggagc tgtaatcgtt acaagcatca tcggctcaag gatagctggt
    25141 tgtgctgatt tagctgcttc tttaagagca agagatgctg cgatcttgaa ggcagtttca
    25201 gatgagtcga catcgtggta tgaaccatcg taaagtttag ctttaacgtc aaccattggg
    25261 taaccagcaa gaacaccgtt tgccatagat tcgatcaacc ctttttcaac agctgggata
    25321 aattcacgag gaaccacacc accaacgata gcattttcga attcgaaacc tttaccttct
    25381 tcatttggtg taaattcaat ccaaacatca ccgaattgac ctttaccacc agattggcgt
    25441 ttgaagaatc cacgagcttg tgtagaagca cggaatgttt cacggtaaga tacttgagga
    25501 gcaccaacgt tagcttcaac tttgaactca cgtttcatac ggtcaacaag gacatcaagg
    25561 tgaagttcac ccataccagc gataactgtt tcaccagttt caacgtttgt ttcaacgcgg
    25621 aatgttggat cttcttcagc aagtttttga agggcaacac ccatcttgtc ttggtctgct
    25681 ttagattttg gctcaaccat caactggata actggttctg gaacttcgat tgactcaaga
    25741 ataacttttg ctttttcatc agtcaatgag tcaccagttg ttgtgtcttt caaaccaaca
    25801 gcggcagcga tgtcaccagc gtaaactgtt tcaatttctt gacggctgtt tgcgtgcatt
    25861 tgaaggatac gtccgatacg ctcacgttta ccttttgatg tgttcataac gtaagaaccg
    25921 ctattaagaa cacctgagta aacacggaag aatgtcaaac gacctacgaa tgggtcagtc
    25981 atgatcttga aggcaagagc tgcaaatggc tcttcatcag atgctggacg ttcttcttca
    26041 gcatctgtat ccgggttaac acctttgatt gcagggatgt caagtgggct tggaaggtat
    26101 gcgataaccg catcaagcat caattgaaca cctttgtttt tgaaggcaga accacaaagt
    26161 actgggaaga attcaacgtt gattgttgct ttacggatac cagcaatcaa ttcgtcgtta
    26221 gtaatttctt caccttcaag gtatttcatc atcaagtctt catcagtttc agcaactgct
    26281 tcgattaatt tttcacggta ttcttgagct tgctctaaat attcttctgg aatatcttct
    26341 tcaaggatat ctgtaccaag gtcgttggta tagatttctg ctttcatctt gatcaagtca
    26401 atgataccac ggaaatcatc ttctgcaccg attggcaatt ggattgggtg tgcatttgct
    26461 tgaagacggt catgaagggt ttgtactgag taaaggaagt cagcaccgat tttatccatt
    26521 ttgttggcga aaacgatacg tggaacaccg tattcagttg cttgacgcca aactgtttca
    26581 gtttgaggct caacacctga ttgtgagtca agaacggtta cagcaccatc aagaacacgg
    26641 agagaacgtt gtacttcgat ggtgaagtcc acgtgtcctg gtgtgtcgat gatgttaacg
    26701 cggtgaccat cccattgagc tgttgtagcg gcagaagtaa tagtgatacc acgttcttgc
    26761 tcttgctcca tccagtccat ttgtgatgcg ccttcgtgtg tttcaccgat tttatgaatt
    26821 ttaccagtgt agtaaaggat acgctctgtt gtagttgttt taccagcatc gacgtgagcc
    26881 atgataccga tattacgagt ttttgcaagt gaaaattcgc gagccatgtg tttctcctat
    26941 ttttttagtt tactctttca ttatagcact atttagcaaa aacggatagg caggacctac
    27001 ccgttatcta aatatttgtt ggtaaagata atacctattg cctttataag gcttggtatc
    27061 ttattcattg aactcaggct aaacgctgtg tgaaaaagat aaactttcct agaaacaaag
    27121 gtttcttcgt caaatttcct attttcactt tgcgttctat acaccttcgt atcttaatta
    27181 attgagttcc agctacaaac cactgacaaa aagataatag ttcctagaaa ctgaagtttc
    27241 tgcgtcacta ttcctatttt gtcttggact tgcttaacac tctcacatct tatattagtt
    27301 gaattttagc tacaaatgtc tgccaaaaag ataaaattgc ctagaaactg aagtttctgc
    27361 gtcaatttcc ctattttggc tagcatttgt ttgacgctaa aatatcctat attaccaacg
    27421 gaagtgtgca aaggcacggt tagcttcagc cattttgtga gtgtcttcac gtttcttaac
    27481 tgatgcacct gtgttgtttg cagcatccat gatttcttta gcaagacgat ctttcatagt
    27541 gtgttcacca cgagctcgtg atgcgtttac caaccaacga agtccaagtg ttgtacgacg
    27601 ttctggacga acttcaactg ggacttggta gttagaacca ccgacacggc gtgcgcgtac
    27661 ttcaagtaca ggcatgatgt tgtccatagc tgtttcaaat acttcaagag cgtcatttcc
    27721 tgttgcttct ttgatagcgc tgaaagcatc gtaaacaata gtagcagctg taccacgttt
    27781 accgtcaagc ataacacggt tgataagacg tgttacgatt tttgagttat ataatggatc
    27841 tggtaatact tcgcgtttag gcgcttgatt tttacgactc attttctctt atcccccttc
    27901 tattatcctt ttggacgttt cgcaccgtat ttagaacggc cttgtttacg gtcggcaaca
    27961 cctgcagtat caagtgcgcc acgaacgata tggtaacgta cccctggaag gtcttttaca
    28021 cgtccgccac gaataagaac aacgctgtgc tcttgcaagt tgtgtccgat acctgggatg
    28081 taggcagtta cttcaataag gttgctcaaa cgtacacgag cgaatttacg aagggctgag
    28141 ttaggttttt taggtgtcat tgttccaaca cgagtagcaa cgccacgttt ttgtggggca
    28201 gccattttag tttgaacttt tttgtgactg ttgtaaccaa tgttcaaagc tggtgaatct
    28261 gatttttcaa ttttagattt acgtggttta cgtaccaact ggttaattgt aggcatctac
    28321 attctcctgt gtttttttat ttttggttga tatagcactt ggtgacagcc catatccggt
    28381 gcactttttg caacaattgt cagcacgtct ctgtacactt ttgagagacc aaaagtaaaa
    28441 agtaccgtct aatataataa cacagacggt acttcatgtc aaatagaatt ttttctttga
    28501 tgcgattgct tatgacgaat gcatcaccta gattccttac ggaacctaaa tcctgtgagg
    28561 ccgacagctg ccaacataac gactcctgct ttaagagctc tttgagtact ttcatcaaca
    28621 tcagaaatga gattgctcgt tgtagaagat cctgagccat aagatgtctt agatgagggc
    28681 tgagtaatcg aagatgtgat tttagacaca atggcattac ttgctaccat ttcagaggtt
    28741 tggccaacaa gcgcttctgc tacaagactt gtattttcag cagctaatct tgctgaagct
    28801 tctaatagtt gtttcgtttc tttaaccatt tcttgaacaa gcggagtagt atctatctta
    28861 ctatatgata gcggttttac gcccgtaaga ggtggagcta cttgcaaatc aggcacagta
    28921 gctatatctt cgtctaagtg gcgatattcc ttttcattag ctaaggtttt aagcaaagtc
    28981 aactgatgtt ctgtggtagc aatagtagct tctagactgc tttgtttagc ttgtaaggct
    29041 gctaaagctt cttgtgcatt taacaaagat gaggtagttt tagccaaatc ttgcttagta
    29101 ttatcaatgc gctcacgtat cacttgaagg cggttaggat tcaatttaaa gtcccttaga
    29161 tattgcaaat gagctttttt agccaccagt gctgtcactc tggctgcggc ttgctctgct
    29221 aaggcttctg tctggtgcag tgcggctttc aacgatgcta gcttagctaa tgattgatca
    29281 cgagtagctt cgagttgtgc ttgttttgct ttagctgcta gtaattctgt tctcaaagaa
    29341 cctttagtat catttaattg tctcacttgg aggtttaagc tgtctgactg cttaagtgtg
    29401 cttgctaatt taccttcaag ttgacttact ttagcttggg ctgccataat atcagcttct
    29461 tgatgaatag ccgacaaacg attttctaat gagcttactt ttcctttgat cgctgcaata
    29521 gtatcagata cagtgcctac tctttgggca taatcttttg tacttccaac ggcttttata
    29581 ggggtcttat taaagcgttg atggttagca atgttagact ctggaaacat tacaaagtgt
    29641 tcattcaaag atcctacatt gctggttgaa aatccaaggt aaacaggcgc attagggtta
    29701 cgtttatcta cacgtaaaaa gttaatagca tggccatatg tatttccgtg taaatgatct
    29761 gtaaagagca tatacttgat actgtcataa ataccacgtt taataccatt cacagtatgc
    29821 acatcgttaa aagcaccgat attctcgtac atgttatcat catttcgaat gagccctgac
    29881 gctccggcag agtcttcaat aatagtttta tcatgaggcc caacaccata atgccctgat
    29941 acccctggct gtccgtagac aaatgatggt cttgtattac catgagtttt cttatagctg
    30001 gtactaagta atcttgcaaa ttcttgtgat cctgctgtaa cagtaactgg tggtagacct
    30061 aattgtcttc ttacactatt aatcatgtga gctgcaaact gcgctagctc attttgcact
    30121 tctggtgtca aattatcggg atcaacaaag cgattacgat ctgctggaat atcttggtat
    30181 tgatttaatt gattacctgg actagctttg gcaataattt gatctgcatg ctctttgtaa
    30241 taattattgt aactagctga tccaatataa ccactagctt ctaatttttt aagttcttca
    30301 agaggatagc cttgcggtgc tttcatggta ttattaccca caatgctatc ttgagtagac
    30361 ggagctgagg atttaaggcg actaagttct gcctcttttt ctgctagagc agctttctga
    30421 gctgccaact cttcagtcaa ttgcttttta actttagctt tttgattttc taagtcagct
    30481 ttagccttct ccaattctga gcttaatgct tttgtattat cattagccgt ttgagctgct
    30541 ttagtgatag catcaggatt gctaatcata gcattgagct tagcaatatt ttgttcagac
    30601 gttttgactt gttccactaa atcttgagct cgagtagttt ctgctgaaat gctagctttt
    30661 tgttctgaca atgcagtctc ttttgaatgt tgatctactt gagcattatg aagctctgtt
    30721 tcagtagctg ttaactctct ttgatgttcg gctccttggg ctaatagcgt ctcctcacta
    30781 cttgcaagag tattagtgta aatttcttgt gcagaggtta aagctttttg ttcattatct
    30841 tgctgctctt ttaagtggtt gatttcagca gtagtttttg tcagagcggt agcaagctct
    30901 gtcagttctg ctttttgttg actgagagtt ttttcaactg catcaatagt tgcctttgcc
    30961 tcttgaattg tttctggttt tggtaaacta tcgtcgtgag tattactcgc cttcgtttct
    31021 cctgaggctc tatcatctgc tttgacttgg tgagatacac ctacactggc actcaataaa
    31081 gcaattgttg aggttaaagc aattttctgc ttaacttggt ttggcttcgt ttgttctaag
    31141 tccattctct ctcctttttc catttatcga aaatattacc aacttctaca acaacattgt
    31201 tgtttttgac atcaatctct gaaactttca gcaatgattt gaaggtcatt tgctcacgct
    31261 ctgattgagc gttttctgca aacacagcaa caccaactaa agtgctgtca aattctgtca
    31321 agagactgat cattcctgta atcg
//
LOCUS       DAXMQE010000019        30368 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.019, whole genome shotgun sequence.
ACCESSION   DAXMQE010000019 DAXMQE010000000
VERSION     DAXMQE010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30368)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30368)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30368
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.019"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            complement(<1..114)
                     /locus_tag="ACF4ZO_001070"
     CDS             complement(<1..114)
                     /locus_tag="ACF4ZO_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system mRNA interferase
                     toxin, RelE/StbE family"
                     /protein_id="HFD5486622.1"
                     /translation="MKEYQVTMSDDAKADLLSIYHYVRDELCAPQAADNLLE"
     gene            complement(114..416)
                     /locus_tag="ACF4ZO_001071"
     CDS             complement(114..416)
                     /locus_tag="ACF4ZO_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HFD5486623.1"
                     /translation="MAKTGTLNLRVDDSVKSAADDILKRLGIPMSTAIDMFLNQIILT
                     GGIPFDVSLPEAPQRVNVDYMSQEKFYDKLITSFEDAKTGNRQDVREFLSQLKENA"
     gene            complement(471..629)
                     /locus_tag="ACF4ZO_001072"
     CDS             complement(471..629)
                     /locus_tag="ACF4ZO_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase"
                     /protein_id="HFD5486624.1"
                     /translation="MRQAPGGNIKPDKEKSVEKIDGIVGLILGLDRCIRRQGDEASVY
                     DERGILSF"
     gene            663..1556
                     /locus_tag="ACF4ZO_001073"
     CDS             663..1556
                     /locus_tag="ACF4ZO_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-three component system protein"
                     /protein_id="HFD5486625.1"
                     /translation="MTTMLDFPFHHEFIEFLGRWTHILITLPKRHHGQVDTAIPRYLL
                     VTIREKTGIVKLTTVQNTAFTTPSNQLKKQYGQFLLTESNNCCACPGCDRPLILTSGN
                     LAAENYEVSAIEKDKDAEPLNLIALCPDCFLTYQADSRKKIVTALKNVKKILVSAHNS
                     QQAISDMKLDSGIVSVLTSLNKLKCDEYDISYDSKQLTDKISPENNRTLYQLVKNQVI
                     DNYLTIQKIIVNLDKQGKIDYEEIQYQTRSMYKKLKAAKHNNLAIFNTISEKLHMATL
                     QDIYFCQMIVSYFIQKCEVLE"
     gene            1556..1780
                     /locus_tag="ACF4ZO_001074"
     CDS             1556..1780
                     /locus_tag="ACF4ZO_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-three component system middle component 7"
                     /protein_id="HFD5486626.1"
                     /translation="MQLPNKLYSYQKSTLAYLPRVLNEIKSGNSNVKDIFHAISEELD
                     DPTDFLSIMDCLYALNAIEMSNEGEVKLCL"
     gene            1771..3429
                     /locus_tag="ACF4ZO_001075"
     CDS             1771..3429
                     /locus_tag="ACF4ZO_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2326 domain-containing protein"
                     /protein_id="HFD5486627.1"
                     /translation="MLIEMWSPVFKKHGEIREPIQFHSGLNVIMGMDLADNSIGKSSS
                     LLAIDFIFGGNSYLKSIAVKKLGDHPIYFCFQFEKKFYFSRDTADPDIILVCDKSYSP
                     TGETMDLGIFLNKLKKRYHLDSSELSFRLAMSGFFRIAGKSNQNTDFPLQVYSSQKSS
                     ESITTLIQLFNLYDNIARYKERLKDKSDQLTTFRNARKYAFISNLVGGKKQFEANVSE
                     IKRLEYDLSHLQDTQQDKIDSDDIEKNQQKLQLRNTKLELDNSLRDKQRRLKLLDISI
                     EFGLYPTESDLTELQQYFPDTNLKKLYEVEAYHKKLATILDSEFSTERESLIAEIDEL
                     ESQLTTLSQELQELGNIPNLSSEYLENYSKLTATINALKEQNEAYLKESGLSKEKSEA
                     DADLKRSTEDILLDLEVKINSKMREFNNILYPDIRKAPQINLNAHNSYSFYTPDDDGT
                     GTKFKGMIVFDLVMLYLTNLPALAHDSLLLSNVSYQATEALLKLYDQSRSLNKQVFLA
                     FDKASSYSPDANQLLSENTVLRLSSNGNELYGISWNKGENSDEI"
     gene            3419..3628
                     /locus_tag="ACF4ZO_001076"
     CDS             3419..3628
                     /locus_tag="ACF4ZO_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD5486628.1"
                     /translation="MRFSYNKLWKLLIDKGWTKTKLRQEAGISSSTIAKLGKGENIIT
                     DILLEICIALDCKIEDIVEIVDNNI"
     gene            complement(3731..4939)
                     /locus_tag="ACF4ZO_001077"
     CDS             complement(3731..4939)
                     /locus_tag="ACF4ZO_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFD5486629.1"
                     /translation="MNNRKKNIQYLVYSKVIYRIGDVMFDFANNTFLAGLNPASLSLV
                     AVYQSLESVIGVLFNLFGGVIADSFKRKKIIITTNILCGTACLVLSFLTKEQWLVYAI
                     VLTNVILAFMSAFSSPSYKAFTKEIVKKDSISQLNSLLETTSTVIKVTVPMVAIFLYK
                     LLGIHGVLLLDGLSFLIAALLISFILPVNDEVVIKEKVTIREIFNDLKIGFKYVYSHK
                     SIFIITVLSALVNFFLAAYNLLLPYSNQMFGEISTGLYGTFLTAEAIGGFIGAILSGF
                     VNKELSSMRLILFLSLSGLMLMLAPPFYIMFHNAIILALSPALFSLFLSIFNIQFFSL
                     VQKDVDNDFLGRVFGIIFTITILFMPIGTGFFSVALNPNNSFNLFIIGSCITILSLVF
                     RILFKKYNIR"
     gene            complement(5024..5317)
                     /locus_tag="ACF4ZO_001078"
     CDS             complement(5024..5317)
                     /locus_tag="ACF4ZO_001078"
                     /inference="COORDINATES: protein motif:HMM:NF015665.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP binding domain-containing protein"
                     /protein_id="HFD5486630.1"
                     /translation="MNSSAKTIGIYRINSKKDSDNCRESSTIDVAKLLKSSGKDVIIF
                     EPLINQKKFLGCPLINDFNEFIKYSDIIVANRIDDALRKCNSKVFTRDIFQYD"
     gene            complement(5411..6180)
                     /locus_tag="ACF4ZO_001079"
                     /pseudo
     CDS             complement(5411..6180)
                     /locus_tag="ACF4ZO_001079"
                     /inference="COORDINATES: protein motif:HMM:NF013175.4"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
     gene            complement(6872..7861)
                     /locus_tag="ACF4ZO_001080"
     CDS             complement(6872..7861)
                     /locus_tag="ACF4ZO_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFD5486631.1"
                     /translation="MFVIGIPTLNEADNISRLVKQIDEYAVNLGKEIIIINSDSKSTD
                     GTPQIFLETKTYNTKVSIVSEAKGKGYNVRNIFEYAINHVPNFSGLILIDGDVVSMKK
                     MWLEKMFIAIESGNDLIIPNYARKSFEGNATNHFIYPMLVKFFKRDMPYQCISGDFGF
                     SRGLIKDLTLKCNWHKYTLGYGIDIFLTLTAILKSYKIKEIDLQSKIHKKSFEKIEKI
                     FLEVSQSFFETINDNSLNQDKLRLNINFESHSRQFIKSSDILSSNDIENLKLRALFLL
                     EEEKQYPHGLSEVEWDGILSNTINNIYRYSSEEHSLYLLPLYLLRVYNYLKYN"
     gene            complement(7916..8884)
                     /locus_tag="ACF4ZO_001081"
     CDS             complement(7916..8884)
                     /locus_tag="ACF4ZO_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein kinase"
                     /protein_id="HFD5486632.1"
                     /translation="MFMMDKTVLYFGLVEISFDVPDFIFQKIKEQNNKIRYYSKSINI
                     LGSVKFINSNQQFIEYDGNGNILVYGRLKYFKEGISLYYIGEYLAECLLIEHSDTLLI
                     HAAAVYNPLSGHSILLLGDKGAGKTTVAMRLCIEHGYHLIGNDQVIFGSNSGILLTYA
                     GTSFFKIRRTAVLSDNLLFKLFSKFFNRSLQFNKASWDDKISIFPKELGIRTCNFSTE
                     ISKIYYIKTDKKEKQIYHSIWSDSLASLYLNELLGRHISGQVACFQSDNGKYFSTMPL
                     INYEKNNRVREQIVKGIFAKQKLFKITAATPAKIAEAIIENVKKNS"
     gene            complement(8868..10067)
                     /locus_tag="ACF4ZO_001082"
     CDS             complement(8868..10067)
                     /locus_tag="ACF4ZO_001082"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HFD5486633.1"
                     /translation="MDLKITNGFYDPSHLSYEVVERKGLGHPDTLADGIAEQIEIDYS
                     LYCLDKFGVIPHHNFDKIIIRGGHSVQDFGGSDFIEPIKIIFLGRASKKCFNSSIPLF
                     KIQKKAATKYLNRILPNLDVENYVEFETLTSDFTTKTNWFSPEAIEDLPEYLDVPKAN
                     DTATMISYWPLTISEELALMIEGYFYKLDKNELPTPRFTKMGGDIKVMVVRNDLEYSI
                     RINFPLISKFFNNDIESQLYVDKHVEKIKKYIEQKYKNISFSIDYHYYLTTTGSCIDF
                     GEEGAVGRGNKTHGIISSFRPNTMEAPAGKNCTYFVGKVWGFLSDTIAKEIYEAFNTP
                     CQIIMQLNIGSKLYRPTHLFIQTEESVDQERVLEIVNRHLNNGKQNTNLILSTQHFIP
                     KTNVYDG"
     gene            complement(10077..11063)
                     /locus_tag="ACF4ZO_001083"
     CDS             complement(10077..11063)
                     /locus_tag="ACF4ZO_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydrogenase"
                     /protein_id="HFD5486634.1"
                     /translation="MSRNPDCKNILIIGFGKIGKIKAYKWLSRGYEVYVKDLKFSSMK
                     YLNTNSDVLDDLSRQYFTIEICTPTNHHLTLLKTVITRYVYSYISIEKPLCNRLEDLE
                     EMKSLVESHPHLAKKIFASEQYFFSKILEKLLQVDCFSLDKIKEITVNFSKDRIEDNE
                     NGRFLDKEILGYGIEIPHIIAVISYLGISLEEFKKGIFVNAIYIKDLEKHDYSIEILS
                     CINQTVIKIISNLGSFAIREGKIEGGDAKTVRRVTIDDKTILFDPHPKLERYKSELVT
                     GTNTFQIHDDMMDTYISLLEGNAIPEDCYINNAIEITKLLINLYSECEKIYL"
     gene            complement(11056..11790)
                     /locus_tag="ACF4ZO_001084"
     CDS             complement(11056..11790)
                     /locus_tag="ACF4ZO_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coenzyme F420-0:L-glutamate ligase"
                     /protein_id="HFD5486635.1"
                     /translation="MNLSIFGLKNIPYLKEGDSIEKLIEESIKTSGFFIEDNDVLCIA
                     SKVVSIAEGQVMSLNEIQVSDVAKEIHRNIPRKDPRIIEIMLNLVNRDLSRLDIKKNY
                     IGCRLENGLKLTSGGIDRKSVDEVFLLPNNPDASAKRISEYLKKSLGKNVAVVITDSD
                     GREDKRGATQVAIGIYGIHPLRKTEVIDSQGETIKFQEETLCDMIAACAGLVMGQRGT
                     GIPAVLIRGLDYKWSENTSIKEALNE"
     gene            complement(11792..12628)
                     /locus_tag="ACF4ZO_001085"
     CDS             complement(11792..12628)
                     /locus_tag="ACF4ZO_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="HFD5486636.1"
                     /translation="MTFHITVNLDEISDKLDDSLKFLNRLSIKSCELRMINTKNIIQL
                     SDAELINLKERLQKYNITPISIASPLFKWNIEENHLESNLDLYGISANVTLNEQWLYV
                     RKIIFIAKFLNIKYVRIFGGIGCSVDDFLNNELFLNLLKETEIIFLIENELGTSVSTA
                     DDLLKIGHFIDEKSIKNLKIWFDIANYYIVEPQVDKVIPKLKKYIYYIHCKNYVNNDL
                     GIHYVELGKGIIDYKTIIHEIHEHFIDLIFSLEVHEKEIDKKAEVVRKSYLTLNEYIN
                     GG"
     gene            complement(12625..13551)
                     /locus_tag="ACF4ZO_001086"
     CDS             complement(12625..13551)
                     /locus_tag="ACF4ZO_001086"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004764 - shikimate 3-dehydrogenase
                     (NADP+) activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HFD5486637.1"
                     /translation="MLVLYVSSKLIKRRRMKFMYSALLGNPVEHSISDELFEYLNHNI
                     GVLDEYKHKKILVDSVCLEDKIKHLINDPKCIGLNITLPYKREVMRYIDNLDRVAEIT
                     GSVNNIYKSGNIITGTNTDWKGIYNTLVFFNISHITKCCVLGTGGTARAAIFTLQKLQ
                     ISPTVVYREPISENTRSLIKSFPDLKYITYKELADQQILNDIEIIINTTPVGMINYEE
                     SLPINFDHLDNVNYKDKYFIDVVFNPLHTKLHEYFGKKGAKIIDGLWVLIFQGIEAFS
                     LWSDKINDGKYFFSKDDVVLIHTFLEGKIKGK"
     gene            complement(13620..13691)
                     /gene="shp3"
                     /locus_tag="ACF4ZO_001087"
     CDS             complement(13620..13691)
                     /gene="shp3"
                     /locus_tag="ACF4ZO_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_128650800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide pheromone SHP3"
                     /protein_id="HFD5486638.1"
                     /translation="MKKISKFLPILILAMDIIIIVGG"
     gene            13771..14622
                     /gene="rgg3"
                     /locus_tag="ACF4ZO_001088"
     CDS             13771..14622
                     /gene="rgg3"
                     /locus_tag="ACF4ZO_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985634.1"
                     /note="Regulator gene of glucosyltransferase 3; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg3"
                     /protein_id="HFD5486639.1"
                     /translation="MKSKLGVTLRKVRKGKQISLCFVADEHLSKSQISRFERGESEIS
                     CIRLINILDKLHITLDEFLILHDEDYTNSETFANLVQYIRKQYSSQNINNIACLLSDT
                     SDYTLNSFEKTMVKSILHTMDSSIIPSDDELLQLTDYLFKVEKWGYYEILLLGNCVRT
                     INYNSYFLLTKEMLNNYIYSSRNKTNKRIVTQLAINCFILSINKEEFSNCSYLIDEIK
                     TLLDNELNFYEQTVFLYATGYFEFKRQLETGVEKMKQAIQVLDILNEDKLKLHYADHF
                     DKLVNKD"
     gene            complement(14876..18415)
                     /gene="smc"
                     /locus_tag="ACF4ZO_001089"
     CDS             complement(14876..18415)
                     /gene="smc"
                     /locus_tag="ACF4ZO_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HFD5486640.1"
                     /translation="MFLKEIELEGFKSFADKTKIEFDKGVTAVVGPNGSGKSNITESL
                     RWALGESSAKNLRGGKMPDVIFAGTQNRNPLNYAKVAVVLDNSDHFIKTAKKEIRVER
                     HIYRNGDSDYLIDGRKVRLRDIHDLFMDTGLGRDSFSIISQGRVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRKKETQIKLNQTQDNLDRLEDIIYELDTQLAPLEKQAKVAKQFLEL
                     DANRKQLQLDILVKDIDIAQERQTKDTEALTALQQDLASYYAKRQSMEEDYQKFKQKK
                     QVLSQESDQTQTTLLELTKLIADLEKQIELVKLESGQEAEKKAEAKKHLEQLQEQLDG
                     FQAEEKQRTEQLLHIDQQLCDVKQQLNELSNALERFSSDPDQLMETLREEFVLLMQKE
                     AALSNQLTALKAHLDKEKQARQHKAQEYQLLVTKLDQLNDESQKAQAHYKAQKEQVEM
                     LLQNYQEGDKRVQELERDYQLNQERLFDLLDQKKGKEARKASLESIQKSHSQFYAGVR
                     AVLQSQKKLGGIIGAVSEHLSFDSDYQTALEIALGANSQHIIVTDEAAAKRAIAYLKK
                     NRQGRATFLPLTTIKARSLSEHYHRQLTTCEGYLGTAESLVRYDDSLSAIIQNLLSST
                     AIFETIDQANIAARLLGYKVRIVTLDGTELRPGGSFSGGANRQSNTTFIKPELEQISE
                     ELTRLVEQLKITEKEVAALQSDLIAKKEELTQLKLAGDQARLAEQRAQMAYQQLQEKQ
                     EDSKALLAALDQSQTTHSDESLLAEQARIEEALTAIAKKKNVLTCDIDDIKENKDLIR
                     QKTQNIHQALSQARLQERDLLNEKKFEQANQSRLRTQLKQCQQNILKLESILNNNVSQ
                     DSIQRLPQWQKQLQDATEHKSGAQKRLVQLRFEIEDYEARLEETAEKITKESEKNDTF
                     IRRQTKLETHLEQVANRLRAYAKSLSEDFQMTLADAKEVTNSIDHLESAKEKLHHLQK
                     TIRALGPINSDAINQYEEVHERLTFLTSQKTDLTKAKNLLLETINSMDSEVKARFKVT
                     FEAIQKSFKETFTQMFGGGSADLVLTETDLLSAGIEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFAIIRVKTIPFVILDEVEAALDEANVKRFGDFLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGITMQESGVSKIVSVKLKEAQEMTN"
     gene            complement(18416..19108)
                     /gene="rnc"
                     /locus_tag="ACF4ZO_001090"
     CDS             complement(18416..19108)
                     /gene="rnc"
                     /locus_tag="ACF4ZO_001090"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004525 - ribonuclease III activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HFD5486641.1"
                     /translation="MKQLEELLSTSFDIQFNDLTLLETAFTHTSYANEHRLLNVSHNE
                     RLEFLGDAVLQLIISEYLFAKYPKKTEGDMSKLRSMIVREESLAGFSRFCSFDAYIKL
                     GKGEEKSGGRRRDTILGDLFEAFLGALLLDKGIDAVRRFLKQVMIPQVEKGNFERVKD
                     YKTCLQEFLQTKGDVVIDYQVISEKGPAHAKQFEVSIVVNGAVLSKGLGKSKKLAEQD
                     AAKNALAQLSEV"
     gene            complement(19540..20349)
                     /locus_tag="ACF4ZO_001091"
     CDS             complement(19540..20349)
                     /locus_tag="ACF4ZO_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFD5486642.1"
                     /translation="MNESGFKYSILASGSTGNCFYLETPKKRLLIDAGLTGKKITSLL
                     AEIDRKPEDLDAILITHEHSDHIKGVGVMARKYHLDIYANEKTWQLMDECNMLGKLDA
                     SQKHIFQRDKVLTFGDVDIESFGVSHDAVDPQFYRIMKDNKSFVMLTDTGYVSDRMTG
                     IIENADGYLIESNHDIEILRSGSYPWSLKQRILSDLGHLSNEDGAGAMIRSLGYNTKK
                     IYLGHLSKENNIKELAHMTMVNQLAMADLAVGTDFTVHDTSPDTACPLTDI"
     gene            complement(20353..21705)
                     /gene="vicK"
                     /locus_tag="ACF4ZO_001092"
     CDS             complement(20353..21705)
                     /gene="vicK"
                     /locus_tag="ACF4ZO_001092"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HFD5486643.1"
                     /translation="MTRDIIGNLSTFELAILILLVFVAFYFIHLAVRDYRNARIIRMM
                     SHKIRDLINGRYTDIIDEKADIELMELSDQLNDLSDVFRLTHENLAQEKNRLASILAY
                     MSDGVLATDRSGKIIMINETARKQLNLSKEEALKKNITDLLEGDTSYTYRDLVSKTPV
                     VTVNSRNDMGEFVSLRLRFALNRRESGFISGLVVVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALKEDIAPSFIKVSLDETNRMMRMISDLLNLSRIDNQVT
                     QLAVEMTNFTAFITSILNRFDLVKNQHTGTGKVYEIVRDYPITSVWLEIDNDKMTQVI
                     ENILNNAIKYSPDGGKITVRMKTTDTQLIISISDQGLGIPKTDLPLIFDRFYRVDKAR
                     SRAQGGTGLGLAIAKEIIKQHHGFIWAKSDYGKGSTFTIVLPYEKDAAIYEEWEEDVD
                     "
     gene            complement(21698..22408)
                     /gene="yycF"
                     /locus_tag="ACF4ZO_001093"
     CDS             complement(21698..22408)
                     /gene="yycF"
                     /locus_tag="ACF4ZO_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019321978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator YycF"
                     /protein_id="HFD5486644.1"
                     /translation="MKKILIVDDEKPISDIIKFNLTKEGYDIVTAFDGREAVTIFEEE
                     KPDLIILDLMLPELDGLEVAKEIRKTSHVPIIMLSAKDSEFDKVIGLEIGADDYVTKP
                     FSNRELLARVKAHLRRTETIETAVAEENASSGTQELTIGNLQILPDAFVAKKHGQEVE
                     LTHREFELLHHLANHMGQVMTREHLLEIVWGYDYFGDVRTVDVTVRRLREKIEDTPSR
                     PEYILTRRGVGYYMKSYD"
     gene            complement(22570..23604)
                     /locus_tag="ACF4ZO_001094"
     CDS             complement(22570..23604)
                     /locus_tag="ACF4ZO_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3114 domain-containing protein"
                     /protein_id="HFD5486645.1"
                     /translation="MCYNMVKKDEEKAMKQAILDRYQALKCYQNAGLSNQAFRAIAKE
                     PIIDNRLGSPTFWVIWPIEKENQSAKQLLTFLLDLVEMPFELSGQLHETQTLLTRFHP
                     SLLPDHIFWKELASLVDQAFPGKTLSQAGELEKRLHQFRYVISSQQAQSIRNHYKMIE
                     MTDAQALALFLRSKKGPCLWRQAPDYTLMDSARLHNKLRFEDNKVIFPSQEVSYNIKV
                     LLWFHTEFILDSTGFFLNEVDAEIVTEKGIVNGASFNYGTDGPRHWDLDVDPINRHDP
                     QFRRDTLKGFRSPKRVFRQWFRAQKDDFMFSYFNAKGLFAYHNKSSFARVKKSAKQFK
                     RQIHPIKGWF"
     gene            complement(23660..24907)
                     /locus_tag="ACF4ZO_001095"
     CDS             complement(23660..24907)
                     /locus_tag="ACF4ZO_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HFD5486646.1"
                     /translation="MLTKLEYWAKQCPNKKAIVADQISLTYQELWQAVLIKDQTIKDS
                     VPYIISHSRYLNQLLSFLQGLKEGSCPIILHPNISGTFQQQIKHVDSELLKKADFAVL
                     SSGTTGKAKLFWRCLSTWTRLFDYQNKVFGMTGNSCLFLHGSFSFTGNLNLALAQLWA
                     GGCLVLSQKLSLKTWLSLWQAKKVSHLYLLPTYLNRLLPYLTKNNMTATHLLTSSQMI
                     SQELLRHYYKKFPQLEIVIFYGASELSFITWCNGRAAVKINGLVGQPFPDVSISFKDK
                     EIFVETPYSVEGMSQPYSVSDLGKMSPAGLILEGRQDDWVNQRGVKCHLPSLVELAHQ
                     APNVKEAHALKIGKGENETLILVLVLTKKDCLAPIKDFLALYLNSGQLPKYYLVIDCL
                     PLKDNGKINREVLLNKIPKQWLS"
     gene            complement(24864..26012)
                     /locus_tag="ACF4ZO_001096"
     CDS             complement(24864..26012)
                     /locus_tag="ACF4ZO_001096"
                     /EC_number="2.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003985 - acetyl-CoA C-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006631 - fatty acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acyltransferase"
                     /protein_id="HFD5486647.1"
                     /translation="MTDVYIAAGLRTPIGLVGKQFAKEQPEILGAKLINALQNKYPVP
                     IDQVICGNTVGTGGNIGRLMTLYSHLGESVSALTVDMQCASAGAALSVGYAKIKAGMA
                     SNLLVGGIESSSLQPESVYASADWRQGAYKVAQFSPDSISPFAMIEGAERVAREHGFT
                     KEYLNHWTLRSHQKASYCQEQALLADLILDLPGASDQGIRPRLSSKVLSKVPPILGED
                     HVISAANACLTHDAAAFLQLSSQPSAFKLIDVVEVAGDPQRSPLMVIKASQVLLEKYG
                     LGMADMTAIEWNEAFAVIDGLFETHYPDLLDRYNIFGGALAYGHPYGASAAIIILHLM
                     RALEIKNGRYGIAAIAAAGGQGFAVLLKYHKEFSHADKARILGKAMPK"
     gene            complement(25981..26550)
                     /locus_tag="ACF4ZO_001097"
     CDS             complement(25981..26550)
                     /locus_tag="ACF4ZO_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486648.1"
                     /translation="MRRLLSTMIKCNQDLPKNSLVVDMTLEKAAQLYENQVLTDTQRF
                     RKIRLSESGLTLEVRFLKKQPVQWLSESTNSNQLEEKANKFLANDDQTINISQAALAH
                     FLEDTGDQKPIHREVPYVLPGAFLLEQVSDKLAIDYRQLHLRFYAPVVLDSSIQLMMK
                     GRAIGLFQAGKLVAKGDYDHDGCLYCCRP"
     gene            complement(26685..27398)
                     /locus_tag="ACF4ZO_001098"
     CDS             complement(26685..27398)
                     /locus_tag="ACF4ZO_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006269097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MIP/aquaporin family protein"
                     /protein_id="HFD5486649.1"
                     /translation="MMNFTGELLGTFILVLLGDGVVSACILNKTKAQNSGWIAIVLGW
                     GIAVTVAVYISGFMSGAHLNPAVTLAMAAIGSLPWSQVVTYLVAQFLGAMLGALVLYL
                     HYYPHWNETKDAGTILACFSTGPAIRHTWSNLFGEALGTAVLVITVMAIGPNKVAAGF
                     GPIIVGFVVMAVGFSLGATTGYAINPARDLGPRIMHALLPIPNKGDSDWSYAWIPVLG
                     PILGGVVGALIYQVILNMM"
     gene            complement(27413..27787)
                     /gene="dhaM"
                     /locus_tag="ACF4ZO_001099"
     CDS             complement(27413..27787)
                     /gene="dhaM"
                     /locus_tag="ACF4ZO_001099"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002960428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047324 - phosphoenolpyruvate-glycerone
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase phosphoryl donor subunit
                     DhaM"
                     /protein_id="HFD5486650.1"
                     /translation="MSDLGIIIVSHSKNIAQGVVDLISEVATDVAITYVGGTEDGGIG
                     TSFDQVQAIVDANPKDDLLAFFDLGSARMNIEMVSDFSDKIITLNVVPIVEGAYTAAA
                     LIQAGADKDAILSQLEELAINK"
     gene            complement(27787..28362)
                     /gene="dhaL"
                     /locus_tag="ACF4ZO_001100"
     CDS             complement(27787..28362)
                     /gene="dhaL"
                     /locus_tag="ACF4ZO_001100"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047324 - phosphoenolpyruvate-glycerone
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaL"
                     /protein_id="HFD5486651.1"
                     /translation="MQAQDAIKWMTLFNDKIQVNKDYLSQLDTPIGDGDHGGNMARGM
                     SAVMENLAGKEFASAADVFKVVAMQLLGKVGGASGPLYGSAFMGLSKASEDSSLADAL
                     QAGLDMIQKRGKAEKGEKTMVDVWIPVIEALKNDGLTKDVVEEAVLATKDIQATKGRA
                     SYVGERSVGHIDPGSFSSGLLFEAMLEAEVV"
     gene            complement(28373..29362)
                     /gene="dhaK"
                     /locus_tag="ACF4ZO_001101"
     CDS             complement(28373..29362)
                     /gene="dhaK"
                     /locus_tag="ACF4ZO_001101"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004371 - glycerone kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HFD5486652.1"
                     /translation="MKKIMNDATQIVDDMLQGLAYMHDDLVERLDGYDVIVRKAEKTG
                     KVALISGGGSGHEPSHAGFVGEGMLSAAICGAVFTSPTPDQILEAIKAADEGAGVFMV
                     IKNYSGDIMNFEMAQELAEMEGIDVASVVVDDDIAVENSLYTQGRRGVAGTILVHKIL
                     GHAAREGKSLADIKALADELVLNIKTIGLALSGATVPEVGKPGFVLEDDEFEYGVGIH
                     GEPGYKKEKLQSSSVLAQELVTKLADSFDMSAGQHYGVLVNGLGATPLMEQYVFANDV
                     AKLLAEKDVTVSFKKIGDYMTSIDMAGLSLTLIKLDKDEWTEALQSDVITPAW"
     gene            29514..30050
                     /gene="dhaS"
                     /locus_tag="ACF4ZO_001102"
     CDS             29514..30050
                     /gene="dhaS"
                     /locus_tag="ACF4ZO_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase transcriptional
                     activator DhaS"
                     /protein_id="HFD5486653.1"
                     /translation="MATSLITKKKIAKAFKKQLAVKSFDKISVVDIMDQAQIRRQTFY
                     NHFLDKYELLDWIFETELQEQVTHNLNYISGFQLLDELLFYFERNKTFYAQLFDIKGQ
                     NDFSSYFVDYCQVLMAKIISEYQSQEMSQSDDADYLAFLTHYHARALADMIKGYVSQS
                     EPKPCLTYLKQLILTSIH"
     gene            30065..>30368
                     /locus_tag="ACF4ZO_001103"
     CDS             30065..>30368
                     /locus_tag="ACF4ZO_001103"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004371 - glycerone kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HFD5486654.1"
                     /translation="MVTILNQTQTLISQYIASVLAAHPHLVQLQDLPIIYNRHLDDQL
                     IPILSGGGSGHEPAHSGFVGDGMLSAAIYGDIFTPPTATDILEALRFLDKGKGVFVI"
BASE COUNT         9691 a         6054 c         4638 g         9985 t
ORIGIN      
        1 ctcaagaaga ttatccgctg cctgtggtgc acagagttca tcacgaacat agtgatagat
       61 gctcagcaaa tctgctttag catcatccga catggtgacc tgatattctt tcattaagca
      121 ttttccttca attgagatag aaattctctg acatcctgac ggttgccagt tttcgcatct
      181 tcaaagctgg tgataagctt atcataaaac ttctcctgac tcatgtaatc aacattaact
      241 cgttgaggcg cttcaggtag agaaacatca aatgggatac ccccagtcaa aataatctga
      301 ttcaaaaaca tatcaatcgc agttgacata ggaataccta agcgtttcaa aatatcatct
      361 gccgcacttt ttactgaatc atcaactcgt aaattcaaag ttcccgtttt agccatggtt
      421 atcctccttt tttgtaacga cattgtatca cgtttttgga gttgactcaa ctaaaaactc
      481 aatatccctc gctcatcata gacgctagct tcatcacctt ggcggcgaat gcaacggtca
      541 agccccagga taagacctac aataccgtca atcttctcaa cagatttttc cttatctggc
      601 ttgatgttgc ctccaggagc ttgtcgcatc accacgtttt gtcccatcca tttaaggact
      661 ggatgaccac catgttagat tttcccttcc atcatgagtt tatagagttc cttggacggt
      721 ggactcatat ccttataacc ctgcccaaaa ggcaccatgg tcaagtcgac accgcaattc
      781 caaggtatct tctggtaacc atcagagaga agacagggat tgtaaagtta accactgtgc
      841 aaaatacagc gttcactacc ccgtcgaatc aactcaaaaa acaatacggg cagttcttgt
      901 taacagaatc taataactgt tgtgcatgcc caggctgtga tagaccactc attctaacca
      961 gtggcaactt agcagcagaa aattacgagg tttcagccat tgaaaaagat aaggacgctg
     1021 aaccactgaa tctgatagcc ctctgcccag attgtttttt aacctatcaa gcagatagtc
     1081 gcaaaaaaat tgtaacagct ctaaaaaatg ttaaaaagat tctagtctct gcacataaca
     1141 gccaacaagc gatttctgat atgaagttag acagtggaat tgtttcagtt ttgactagtc
     1201 tcaataaact aaaatgtgat gaatatgata tctcctatga ctcgaagcaa ttgactgata
     1261 agatatcacc tgagaacaat cgtacgcttt atcaattggt taaaaaccaa gttattgata
     1321 actacttaac cattcaaaaa atcatcgtaa atttagacaa acaaggaaaa attgattacg
     1381 aggaaatcca atatcaaacg cgatcgatgt ataaaaagtt aaaagcagcc aagcataata
     1441 atctggctat tttcaatact atttcggaaa aactccatat ggctacacta caggacatct
     1501 acttctgcca gatgattgtc tcttacttta tccaaaaatg cgaggtactt gaataatgca
     1561 attaccaaat aaactttact cctatcaaaa aagcactctg gcctatttac ctagagtgct
     1621 aaatgaaatc aaaagtggaa actcaaacgt caaagatatc tttcacgcta tctcagaaga
     1681 gttggatgat cctacagatt tcctatctat aatggattgc ttgtatgcat tgaacgctat
     1741 tgaaatgtct aatgaaggag aagtaaaatt atgcttatag aaatgtggtc tccagtattt
     1801 aagaaacacg gagaaattcg ggaaccaatt caattccatt ctggattaaa cgtcatcatg
     1861 gggatggatt tagctgataa ctctatcggc aaatcctcct cactattagc cattgatttc
     1921 atctttggag gtaatagcta tctaaaatca attgcggtta aaaaattagg tgatcatcct
     1981 atctacttct gctttcaatt tgagaaaaag ttttattttt caagagatac ggccgaccca
     2041 gatatcattc tagtgtgtga caagagctac tctccaaccg gtgaaacaat ggacctagga
     2101 atttttctta acaaacttaa gaaacgatat catttagatt cttcagagct atcattccga
     2161 ttagctatga gtggcttctt taggattgct ggaaaaagta atcaaaatac cgatttcccc
     2221 ttacaagttt attcgagcca aaaatcttct gaatctatta ctactctcat ccaacttttt
     2281 aatttgtatg ataacattgc acgatacaaa gaacgtctga aagataagag cgaccagtta
     2341 acaacttttc gtaatgctcg aaagtatgcc ttcatctcca acctggttgg cggtaaaaag
     2401 caatttgaag cgaatgtctc agaaataaaa agattggaat atgatttatc acatctccaa
     2461 gatactcagc aagataaaat tgactctgat gatattgaga aaaatcaaca aaaactccaa
     2521 cttagaaata ctaagctgga gctagataat agtcttcgag ataagcaaag acgccttaag
     2581 ctattggaca tcagtatcga atttggctta tatcctactg aatctgactt aacagagctt
     2641 caacaatact tcccagatac taatctcaaa aaattatatg aagttgaagc ttaccacaaa
     2701 aaattggcaa ctattttaga ttccgaattc tcaactgaac gtgaatccct aatagctgag
     2761 atcgacgaat tagagagtca attaacaact ctaagccaag aacttcaaga actaggaaac
     2821 atcccaaatc tttcaagtga gtacttagaa aactactcta aactaacagc tacaatcaat
     2881 gcactaaaag aacaaaacga ggcctactta aaggagtctg gtctatccaa agaaaaatca
     2941 gaagcggacg ctgacttgaa acgcagtaca gaagatatcc ttctagatct agaagtaaaa
     3001 atcaacagta agatgcgtga attcaataac attctatatc cagatattcg caaagctcct
     3061 caaattaacc tcaatgctca caatagctac tccttctata caccagatga tgatggtaca
     3121 ggaactaagt tcaaagggat gattgtattc gacttagtaa tgctctacct tactaatctg
     3181 ccagcactcg cacacgattc attactcttg agtaatgtta gctaccaagc gactgaagca
     3241 cttttgaagc tatatgacca gtcaaggtca ttgaacaaac aagtcttttt agccttcgat
     3301 aaagccagct cttattctcc agatgctaat caactcttgt cagaaaatac ggtattgaga
     3361 ctctctagta acggaaatga actctacggt atttcatgga acaaaggaga aaactcagat
     3421 gagatttagt tacaataaat tatggaaact tcttattgat aaaggttgga ccaaaacaaa
     3481 gctcaggcaa gaagctggga ttagttcttc cacgatcgca aaattgggaa aaggggaaaa
     3541 tatcattact gatattttat tggaaatttg tattgcactt gattgtaaga ttgaagatat
     3601 agtagaaatt gtagacaata atatctagaa ataaaaaaag cactaagttg ataagatgtg
     3661 taagtcagat caacttagtg cctttacttt gaaaaaaaat aattttctca ataatactta
     3721 gtactaactg ttaacgaata ttatactttt taaataatat tctaaatact aatgacaata
     3781 tagtaatgca cgaaccaata ataaaaagat taaagctatt gttaggattt aatgccaccg
     3841 agaaaaagcc agtcccaata ggcataaaaa gaatagttat tgtaaagata ataccaaaca
     3901 ctctccctaa aaaatcgtta tcaacatctt tctggacaag agaaaaaaat tgaatattaa
     3961 agatggaaag aaataaactg aataaagctg gtgacaaagc taaaataatt gcattatgaa
     4021 acataatata aaatggggga gctaacatta acatcagtcc tgataaagat agaaacaata
     4081 tcaatctcat acttgataat tctttattca caaaaccact taatattgcc ccaataaatc
     4141 caccaattgc ttctgctgtt aaaaaagtgc cataaagtcc agttgaaatt tctccaaaca
     4201 tttgattact atagggcaac aataaattat aagcggctag aaaaaaatta acaagtgcag
     4261 aaagaacggt aataataaag atggacttat ggctgtaaac atatttaaat cctattttta
     4321 aatcgttaaa tatttctctg attgtcacct tctcctttat caccacttcg tcattaacag
     4381 gtaaaataaa ggaaattagt aaagcagcta ttagaaatga tagtccatcc aatagtaata
     4441 caccgtgtat accaagtagc ttatataaga aaattgctac cataggaact gttactttga
     4501 ttacagtact tgttgtctct agcaatgaat taagttgtga tatactatct tttttaacaa
     4561 tttcttttgt aaatgcttta taggatggac tagaaaaagc actcataaat gccaagataa
     4621 cattagttag tacaatggca taaaccaacc attgctcttt tgttaggaac gagagtacta
     4681 agcaagctgt gccacataag atatttgtag taataataat ttttttccgc ttgaaactgt
     4741 ctgcaatgac tccaccaaat aaattaaata gaacacctat gacactttct agagactgat
     4801 atactgcaac taatgataga gacgctggat taagcccagc aagaaaagta ttgttagcaa
     4861 aatcaaacat aacatcgcca attcgatata taactttact atacactaaa tattgaatat
     4921 tttttttcct attgttcatt ttaaaaacct ttaaaatttt cagatataat aacttttaac
     4981 tgaatttatt acttaaaaat attttttcgc aaaaatgttt ttgttaatca tactgaaaaa
     5041 tatcacgtgt aaaaactttt gaattacatt ttctcagagc atcatctatt ctattggcaa
     5101 ctataatatc cgaatattta ataaattcat taaaatcatt aattaaaggg caccccaaaa
     5161 actttttttg gttaattaag ggctcaaaga tgataacatc cttaccactg ctttttagaa
     5221 gtttagcaac atcaattgta gaagattccc tacaattatc cgaatctttt ttggaattaa
     5281 ttctataaat tcctattgtt ttagctgagc tgttcaaaat cgtttttgct atatgaattt
     5341 ttcttaataa attagactca cttatactgg taataattgg tgctggaatt tctttaaaat
     5401 gatactctaa ttgcttaata tccttaggaa gacagtaccc accaaaaccg aaagaaggat
     5461 tattgtgcga atttcctatt ctctggtcat atcccatagc ctcaataatt tttttgagtc
     5521 caaattttgc atttcagcaa acgtatccaa ctcattaaaa aaagcaattt tttgtgccaa
     5581 gtatgcattc gaaaataact ttatcgcttc tgcttcagaa gagccaacta ataaagatgg
     5641 cgagtctttt tcaaccgata tatctgttag tatgtctaag aataattgag aatttctaga
     5701 ttcatttcca actatagttc tcgaaggata caattgatca tgaatagttg atccttccct
     5761 aaggaactca ggtgaaaaaa tgatatcgtt gtagtgaaat tgattcctta aatattctgt
     5821 aaaaccaatt ggaactgtcg actttattac aattgtagcc tttttgttta tctttaaaat
     5881 attacttaca gaaatttcga taatggaagt atcaagctta ttaaatttta ggttggttgg
     5941 caaagacaag attatgaaag tcgcatcctt atatgctaat tcttcagaag aagttgcatt
     6001 aatatttttt gccttacata aaagtttgtt tatagctgct tctttaaggg gggattgcct
     6061 tttatttatt aaatcaattt ttttattatc aatatcaaaa aaggtgacgt cgtgttcctt
     6121 tgcaagtagg agccctatcg ataatccaac gtatccaatg cctacaactg taattttcat
     6181 gttaacctct attctaaaac tttttataaa tcaatttttt tgttagaaag aatataaaat
     6241 tgatttttat acctaaatga gatgatataa atttttggat gtctacttaa gaattcagat
     6301 gtatcagaaa aagaacctag atattccccc tttttttgtt cgtcaacaac accaataaaa
     6361 tgtaaagaaa ttaaagaaat actagtaagc ttagtcttta gttcttgtct ccagcctgaa
     6421 atattgggat agaattcatt aaaaatgaac cctagtctat aatagatcac actatcatct
     6481 tcactgacaa agattggtag atttctcttt ttatattcct caaagtcatc ttcgattgca
     6541 gtcctactag gatttttttc taaccatttc caacgtactc attagcgtct caatcatact
     6601 ggtccccttt ctaagaaaaa acagattttc attaagtgtt tttatctttt aaactcaaca
     6661 caaatatcaa aaatccaaac tggcatctaa cccactaaag tcaattaaag taatccatca
     6721 aaaaattaaa tattatcgtt actactcaaa gtatcaaaaa tattataaat aaatttactt
     6781 acatactgta tttattattt agataagcta aacatattga aatatattcc accaatcaca
     6841 cttcttctca agattaataa aaattgaaaa cttagttgta ctttagataa ttgtatactc
     6901 tcaataaata aagtggtaat aaatataacg aatgttcctc actactatat ctataaatat
     6961 tgttaattgt attagacaaa attccgtccc attctacctc tgacagccca tgtggatact
     7021 gtttttcttc ctctaataaa aacaacgctc ttaactttaa attctcgata tcattgctgg
     7081 ataggatatc actggactta ataaactgtc ttgaatgact ttcaaaattt atatttaaac
     7141 gtaacttatc ttgattcaaa gaattatcat taatagtttc gaagaaactt tgtgaaactt
     7201 ctaaaaaaat tttttcaatt ttctcaaagc tttttttatg aatctttgat tgtaaatcga
     7261 tttccttaat tttgtatgac tttaatatag ctgttaaggt taaaaaaata tctatcccgt
     7321 aacctaatgt atatttgtgc caattacatt tcaaagttaa atcttttatc aatcctcttg
     7381 aaaatccaaa atcaccagag atgcattgat aaggcatatc acgtttgaaa aatttcacta
     7441 acatgggata aataaaatgg tttgtcgcat ttccttcaaa agattttcta gcataatttg
     7501 ggattataag atcatttcca gattcaattg ctataaacat cttttctaac cacatttttt
     7561 tcattgagac aacgtctcca tcaatcaaaa ttaaaccgga gaaattcggc acatgattta
     7621 ttgcatattc gaaaatattt ctcacattat aaccttttcc tttagcttct gatactatcg
     7681 aaactttggt gttataagtt ttggtttcta aaaaaatctg cggagttcca tctgtacttt
     7741 tactatccga attaataata ataatttctt tccctaaatt tacagcatac tcatcaattt
     7801 gtttaactaa tctactgata ttatctgcct catttaaagt tggaatgcct atcacaaaca
     7861 taattactct tactcctttt tcaatacttc atattaatcc ccaaattcac acacactatg
     7921 agtttttctt aacattttct ataatcgctt ctgcaatctt agctggcgta gctgctgtaa
     7981 ttttaaataa tttttgttta gcgaaaatac ccttcactat ctgttctcgt acccgattat
     8041 ttttttcata atttatcaaa ggcattgtag aaaaatattt tccattatct gattgaaaac
     8101 atgcaacctg tccagaaata tgccttccca atagctcatt tagatataga cttgctaaac
     8161 tatcactcca aattgaatga taaatttgct tttctttctt gtctgtcttt atataataaa
     8221 tttttgagat ttcagtagaa aaattacaag ttcgtattcc caactccttt gggaaaattg
     8281 aaattttatc atcccaactt gccttattaa attgtaatga acggttaaaa aatttgctaa
     8341 ataatttaaa cagtaaattg tccgacaaaa cagctgtcct tcttatttta aagaaagatg
     8401 tccctgcata agttagtagt attccagagt tcgaaccaaa tattacttgg tcattaccaa
     8461 taaggtgata cccatgttct atacaaagcc tcattgcaac cgtagttttt ccagcacctt
     8521 tatctcctaa tagtaaaatt gaatggccag ataaaggatt ataaactgct gctgcatgaa
     8581 ttaataaggt gtcactatgt tcaatcaaga gacattcagc taagtactct ccaatgtagt
     8641 ataatgaaat tccttcttta aaatacttta atcttccata aactaaaata tttccattgc
     8701 catcatattc tataaattgc tgattgctgt taataaattt tacactacct aatatattta
     8761 ttgatttgct ataatatcta attttattat tctgctcttt tattttttga aatataaagt
     8821 caggcacatc aaaagaaatt tcaaccaacc caaaatataa aacagtttta tccatcataa
     8881 acattggttt tagggataaa atgttgagtt gacaagatta aattagtatt ttgtttacca
     8941 ttatttaaat gcctgttaac aatttctaat actctttctt gatcaacact ttcttctgtc
     9001 tgaataaata aatgggttgg tctatacaat tttgatccaa tatttaattg cataatgatt
     9061 tgacagggag tattgaatgc ttcataaatt tctttggcaa tagtatcaga caaaaatccc
     9121 caaacctttc ctacaaaata agtacaattt tttccagctg gtgcttccat agtatttggc
     9181 ctaaaacttg atatgatacc atgagtttta ttacctcgac caactgcacc ttcttctccg
     9241 aaatcaatac aagaacctgt agtagttaaa taataatggt aatcaataga aaagcttatg
     9301 tttttatact tttgttcaat atatttctta attttttcta cgtgtttatc aacatacaac
     9361 tgactttcaa tatcattgtt aaaaaattta cttattaaag gaaaatttat tctaatagaa
     9421 tattctaaat cgttccttac gaccattact ttaatatcac cacccatttt agtaaatctt
     9481 ggcgttggta attcattctt atctaattta taaaaatacc cttcaatcat taatgctaat
     9541 tcttcagaaa ttgttaatgg ccaataactt atcattgtag ctgtatcatt tgcctttggt
     9601 acatctagat actccggtaa atcttctatt gcttcaggcg agaaccaatt agtttttgta
     9661 gtaaaatctg aggtcaatgt ctcaaattct acataatttt caacatctaa attaggtaaa
     9721 attctattta aatatttagt tgcagccttt ttctgaattt taaaaagtgg aattgaacta
     9781 ttaaaacatt ttttgctcgc cctacctaga aaaataattt taattggttc aataaagtca
     9841 cttccaccaa aatcctgaac tgaatgtccc cctcggataa taattttatc aaaattatga
     9901 tgtggaataa caccaaactt gtccaaacaa taaagtgagt aatcaatttc aatttgctca
     9961 gcaattccat ctgctaaggt atcagggtga cctaagcctt tgcgttctac tacttcgtat
    10021 gataaatgac ttgggtcata aaagccgttt gtaattttta aatccatagt tacacctcat
    10081 aaataaattt tttcacattc tgaatataag ttaattaata attttgttat ctcaattgca
    10141 ttattgatat agcaatcttc aggaatagca tttccttcta acaaactgat atacgtgtcc
    10201 atcatatcat cgtgtatttg aaacgtattt gtcccagtca ccaattcact cttatacctc
    10261 tcgagtttag gatgtggatc aaatagtatt gttttgtcat caatggtaac tcttcttact
    10321 gttttagcat cacctccttc aatcttgccc tctcttattg caaaacttcc caaattacta
    10381 ataattttaa tcactgtttg attaatacaa gataagattt ctattgaata atcgtgtttc
    10441 tctaagtctt ttatataaat agcattcaca aagattcctt ttttgaattc ttctaatgaa
    10501 attcctaaat aagaaataac agcaatgata tgaggaatct ctattccata gcccaatatc
    10561 tctttatcta aaaatctccc attctcgtta tcctcaatcc tatctttaga aaaattaact
    10621 gttatttcct tgattttatc tagagagaaa caatctactt gtaacagttt ttccaaaatt
    10681 ttcgaaaaga agtattgttc actggcaaaa attttttttg ctagatgtgg gtgactttct
    10741 actagcgact tcatttcttc taaatcttct aacctgttac acagtggttt ttcaatgcta
    10801 atataagaat agacatacct tgttataacg gttttcaata gcgtaaggtg gtgatttgtc
    10861 ggagtacaaa tctcaatagt aaaatattgt cgtgataaat catccaacac atcactattt
    10921 gtattaaggt atttcatgct ggagaatttc aaatctttga catatacctc atatccgcgt
    10981 gatagccact tgtacgcttt aattttccca atttttccaa aaccaatgat tagaatattc
    11041 ttacagtccg gatttctact catttaacgc ttccttaata ctagtatttt cagaccattt
    11101 ataatccaag cccctaatga ggacagctgg aattccagtt ccacgttgcc ccattactaa
    11161 gccagcacaa gctgcaatca tatcacacaa agtctcttct tggaatttta ttgtctctcc
    11221 ttgtgaatct attacttctg tttttctcaa aggatgaata ccataaatac caattgctac
    11281 ttgagtagca cctcttttat cctctctacc atcactatct gttataacaa ctgcaacatt
    11341 tttcccaagt gattttttaa gatattccga aattcttttt gcagaagcat ccggattatt
    11401 aggtaaaaga aatacttcat ctactgattt tctatcgatt ccaccacttg tcaactttaa
    11461 accattttcc aagcgacaac caatgtaatt ttttttgata tctaaacgtg acagatctct
    11521 attgactaaa tttagcataa tttcaattat tctaggatct ttacgtggaa tattcctgtg
    11581 gatttctttt gctacatcac tcacttgtat ctcgtttaaa gacatcacct ggccttctgc
    11641 gatagataca actttagaag ctatgcaaag cacatcattg tcttcgataa aaaaacctga
    11701 agttttaatg ctttcttcaa taagcttttc tatactatcc ccttctttca aataaggaat
    11761 attctttaaa ccaaatatac tcaaattcat tttagcctcc attaatatac tcatttagtg
    11821 tcagataaga cttcctcact acttctgcct ttttgtctat ttctttttca tgtacttcta
    11881 aactaaaaat taagtctata aaatgttcat ggatttcatg aatgattgtt ttataatcga
    11941 taattccttt acctagttct acataatgta ttcctaaatc attgttaaca tagttcttac
    12001 agtgaatata gtaaatatat tttttcaatt ttggaataac cttgtctacc tgaggttcaa
    12061 ctatgtaata atttgcaata tcaaaccaga tttttagatt ttttatagat ttttcatcta
    12121 taaaatgtcc tatttttaac aaatcgtctg cagtgctcac tgaagttcct aactcgttct
    12181 caattaaaaa gataatttca gtctctttta acaaattcaa aaatagttca ttattcaaga
    12241 agtcatctac tgagcaccca atcccaccaa atattcttac atatttgata tttaaaaatt
    12301 ttgcaataaa aataattttc cttacataaa gccattgttc atttaacgta acattagctg
    12361 aaataccgta taaatcaaga ttactctcta aatgattttc ttctatattc catttaaaaa
    12421 gtgggcttgc aattgaaatt ggagtgatat tatacttttg taaccgttct tttaaattaa
    12481 ttaactctgc atcactaagt tgtataatat ttttagtgtt tatcattcgt aattcacaac
    12541 ttttaattga taatctattt aaaaatttca atgaatcatc tagtttgtct gatatttcat
    12601 caagatttac tgtaatatga aaagtcattt tccttttatc ttcccttcta gaaatgtatg
    12661 aattaggaca acatcatctt ttgaaaaaaa atatttacca tcattaattt tatcactcca
    12721 caatgaaaat gcttcaattc cctgaaaaat caaaacccat aaaccatcaa ttatttttgc
    12781 tcctttttta ccaaaatatt catgaagttt cgtatgtaaa ggattgaaaa ctacatctat
    12841 aaagtattta tctttataat taacattgtc caaatgatca aaatttatag gtaaactttc
    12901 ttcataattt atcataccaa ctggtgtagt atttattatg atttctatat catttaaaat
    12961 ttgttgatca gccaattcct tatatgtaat atactttaaa tcagggaaac tctttatcaa
    13021 acttcttgta ttctcactaa ttggctccct gtatacaact gttggtgaga tttgtagttt
    13081 ttgtaaagtg aaaatagcag ctctagcagt accgccagta cctaaaacac aacattttgt
    13141 tatatggcta atattaaaga aaactaatgt attataaata cctttccaat cagtattagt
    13201 tcctgtaatt atatttccag atttataaat attgttaaca gatccagtta tctctgctac
    13261 tctgtctaaa ttgtcaatat acctcattac ctctctttta taaggtaaag ttatatttaa
    13321 tccaatacat tttggatcat ttatcagatg tttgatttta tcttctaaac acactgagtc
    13381 taccaaaatt tttttatgtt tatattcatc cagaactcct atgttgtgat ttagatattc
    13441 aaataattca tctgatatag aatgttcaac tggattacca agcaatgcag aatacataaa
    13501 tttcatcctc ctacgtttaa ttagtttact actaacataa agtacaagca ttacacagag
    13561 ctaaccatta cctataagtc tttagagtat ctaaagactt aggtgtacac ctaagtaact
    13621 tacccaccaa caataatgat aatatccatt gctaaaatta aaatcggcaa aaattttgaa
    13681 attttcttca taagtggact tcctttcagt ttttatttat tgtacaataa aaaaaacgga
    13741 attgattttt gttgggaaag tgggaaaaat atgaaatcaa aacttggtgt cacacttaga
    13801 aaagttcgaa aaggaaagca aattagtctg tgcttcgtgg cagatgaaca cctttcaaaa
    13861 tcacaaatct ctcgttttga gcgcggggag tcagagatat cgtgtatccg actgatcaat
    13921 attctagaca aattacacat tactttggat gagttcctta ttttacatga tgaagactat
    13981 accaattccg aaacatttgc taacctggta cagtatattc gtaagcaata ttcatcacaa
    14041 aatatcaata atatagcatg tttactttcc gacacttctg attacactct gaattctttt
    14101 gagaaaacaa tggtaaagtc cattttacac acaatggatt caagcatcat tccatcagat
    14161 gatgaattac ttcaactaac agattatctc tttaaagttg aaaaatgggg ctactatgaa
    14221 atccttttgt tgggtaactg tgtacgaaca attaactaca actcctactt cctattgaca
    14281 aaggagatgt taaataatta catttactct tcacggaaca aaactaataa acgaattgtc
    14341 actcagcttg ctataaattg tttcattctt agcatcaata aggaggaatt ttctaattgc
    14401 tcctatttaa ttgatgagat aaaaaccttg ttagataatg aattaaactt ctatgaacag
    14461 acagtttttc tctatgcaac aggttacttt gaatttaagc gccaattaga aactggagtt
    14521 gaaaagatga aacaagccat acaagttctt gatattttaa atgaagacaa gttaaaatta
    14581 cattacgctg accattttga taaattagtt aacaaagatt aagtgaaatc attctttacc
    14641 ttttaacgaa atgccaatca agggtgtctc aataaaaaat catctactct gacaactttt
    14701 ctcttttacc tatcgacagc taaaaagcct tggaaactgc tatttccaag gctttctttg
    14761 tactctattg tatcaattag cttattccga tttctgttgc tattagttta atcatgaaat
    14821 ctcctaactt atgaccgaac atccaaaaaa aacagaagga actcccttct gttttttaat
    14881 tggtcatctc ttgagcttct tttaatttta cagatacaat tttagagacc cccgattcct
    14941 gcatggtaat tccataaata ctatctgctg cagccattgt tcctttacga tgggtcacga
    15001 caataaattg actatctttg tcaaagcgat tgaggaaatc cccaaagcgc ttaacatttg
    15061 cttcatcaag agccgcttct acctcatcta aaatcacaaa cggaatcgtt ttaacacgta
    15121 taatagcaaa caataaagcc agtgctgaca aagctttttc tccgcctgac atcaagttaa
    15181 gagattgaat tttcttacca ggaggctgca cagaaatctc tataccagca gacaagaggt
    15241 ctgtttccgt taaaaccaaa tcagcagaac ccccaccaaa catctgagta aaggtttctt
    15301 taaaactttt ttgaattgcc tcaaaagtca ctttgaaacg agccttcact tcgctatcca
    15361 tactattaat agtctctagc aaaagatttt tagcttttgt cagatctgtc ttttgacttg
    15421 ttaaaaaagt caaacgctca tgcacttcct catactgatt aatagcatca ctattaattg
    15481 gtcctagtgc acgaatagtc ttttgtaaat ggtgtaattt ttctttggca ctttctaagt
    15541 gatcaatact atttgttacc tcctttgcgt ctgctagtgt catttgaaaa tcttctgata
    15601 aacttttagc ataggctcgt aagcgattag ccacttgctc taaatgtgtc tctaacttgg
    15661 tttgacgacg aataaatgtg tcattttttt cgctttcttt ggttattttt tctgctgttt
    15721 cttctaagcg ggcctcatag tcctctattt caaatcttaa ttggactaaa cgtttttgag
    15781 caccagactt atgctctgtg gcatcttgta actgtttttg ccactggggt agtctttgaa
    15841 tgctgtcttg acttacgttg ttgtttagta tgctttcaag tttgagaata ttttgctggc
    15901 attgcttcag ctgagttctt agacgagatt gattagcttg ctcaaatttc ttttcattaa
    15961 gtaaatctct ttcttgcaaa cgagcttgag ataaagcttg gtgaatgttt tgtgtttttt
    16021 gcctaatcaa atctttgttt tctttgatat catcaatatc acaagttaag acattttttt
    16081 tcttagcaat agctgttaat gcttcttcaa tacgagcttg ttctgccaat aaagattcat
    16141 cagaatgagt cgtctgactt tgatcaagag cagctaacaa agcctttgaa tcttcttgtt
    16201 tttcttgcaa ttgctgataa gccatttgag ctctttgttc agctaagcgt gcctggtcac
    16261 cggctaattt caattgtgtc agttcttctt tttttgctat caaatcgctt tgcaaggcag
    16321 ctacttcttt ttcagttatt tttaattgct caactaatcg cgttaattcc tcactgattt
    16381 gttctaactc tggtttgata aaagttgtat tgctttgtct attagctcct cctgaaaaag
    16441 aaccacctgg tcgtaattct gttccatcaa gagtaacaat tcttacctta tatcctaata
    16501 agcgcgctgc aatattagct tgatcaatag tttcaaagat agcagtacta gataaaaggt
    16561 tttggataat agctgaaaga ctatcatcat agcgaaccaa tgattctgca gttcccagat
    16621 aaccttcaca agtcgtcaat tgacgatgat agtgttctga taatgatcta gcctttatag
    16681 tagttaaagg taaaaaagtt gctcgtcctt ggcgattttt tttcaaataa gcaattgctc
    16741 tttttgctgc agcttcgtct gttacaataa tatgctgact attagcacct aatgcaattt
    16801 caagagctgt ttggtaatca gaatcaaaag aaaggtgttc actgactgca cctatgatcc
    16861 ctccaagctt tttttgtgat tgaaggacag ctcgtactcc cgcatagaat tgactatgac
    16921 ttttttgaat agattctaag ctagccttac gagcttcttt tccttttttt tgatccaaca
    16981 agtcaaatag tctttcttga ttcagttggt aatctctttc taattcctga acgcgtttat
    17041 caccttcttg ataattttgg agcaacattt cgacttgctc tttttgagct ttataatgag
    17101 cttgagcttt ttgagactcg tcattaagtt gatcaagctt agtaacaagt agctgatatt
    17161 cttgagcctt atgttgacga gcctgttttt ctttgtctaa atgggctttt aaagctgtca
    17221 gctgatttga taaggccgcc tctttttgca tcaataatac aaactcttct cttagagttt
    17281 ccattaattg gtcgggatca cttgaaaaac gctctaatgc attgctcaat tcgtttaact
    17341 gttgtttgac atcacaaagt tgttgatcaa tatgcaataa ttgttctgta cgctgctttt
    17401 cttctgcttg aaaaccatcc aattgttctt gtaactgttc gaggtgtttt ttggcttctg
    17461 cctttttctc tgcttcttgg ccactttcta gcttaaccaa ttcaatttgc ttttccaagt
    17521 cagctattag cttggttaat tctaataatg ttgtttgggt ttgatctgac tcttgactaa
    17581 gaacctgctt tttttgcttg aatttttggt aatcttcttc catagattga cgcttagcgt
    17641 aataagatgc taagtcttgt tgtaaagcag ttaaagcttc agtatcttta gtctgtcttt
    17701 cttgagctat atcaatatct ttgactagaa tatctagttg tagttgctta cgattggcat
    17761 caagttctaa aaattgttta gctactttag cttgcttttc aagtggggcc aactgcgtgt
    17821 ctagctcata aataatatcc tctagacggt ctaaattatc ttgagtttga tttaatttaa
    17881 tctgagtttc ttttttacgt gttttatatt ttaaaacacc agctgcttct tcaaaaatgg
    17941 cgcgcctttc ttcaggttta ctattgaaaa tttcctctac acgaccttga gaaataatgg
    18001 agaaagaatc acgaccaagc cctgtatcca taaacaaatc atgaatatca cggagcctta
    18061 ccttgcgacc atcaatcaga tagtcactat ctccatttcg gtaaatatgc ctttcgacac
    18121 ggatttcttt cttggcagtt tttataaaat gatcggaatt atcaagaaca accgctacct
    18181 tagcatagtt tagaggatta cggttttgtg tcccagcaaa aatgacatct ggcatcttgc
    18241 ccccacgcag atttttagca cttgattctc ctaaagccca acgtaaactt tctgtaatat
    18301 tacttttacc tgaaccattt ggtcctacga ctgcagttac tcccttatca aattcaattt
    18361 tagtcttgtc cgcaaaggac ttgaaccctt ccaactcaat ttcttttaaa aacatctaaa
    18421 cctcactaag ttgggcaagg gcatttttag cagcatcttg ctccgctaat tttttagact
    18481 tacctaaacc tttactaagg acagcaccat taacaactat cgatacctca aattgtttag
    18541 cgtgggcagg tcctttctca ctaatgactt gataatcaat aaccacatca ccttttgttt
    18601 gcaaaaactc ttgaagacaa gttttatagt ctttaaccct ttcaaaattc cctttttcca
    18661 cctgaggaat catgacttgt ttcaagaagc gacgtactgc atcaatcccc ttatctaata
    18721 aaagagcacc taaaaaggct tcaaataagt ctcctaaaat agtatcacga cggcgaccac
    18781 ctgacttttc ctcacctttt cctagtttga tataagcgtc aaaagaacaa aatcgtgaaa
    18841 aacctgccaa gctttcctca cgtacaatca tggaacgtaa cttagacata tctccttctg
    18901 tctttttagg atactttgca aataaatact ctgaaataat caattgtaga acagcgtctc
    18961 ctaaaaattc caagcgttca ttatgtgaaa cgtttaggag acgatgctcg ttagcgtaag
    19021 aagtgtgggt aaaagctgtt tctagtaaag tcaaatcatt aaattgaata tcaaaagatg
    19081 ttgagagtaa ctcttcaagc tgtttcataa aaaatccctt tcatatttgt cagtagacct
    19141 tatttagtat accaaaaatc cacctagaaa accgactcta agtggatttt tcgtgattta
    19201 ttaaacatct taaatacccg tcaaaggaaa ctttctcata caatcaaaag actctacact
    19261 atctgagggg aatgtcccac tacagatagt atagagctat tttgttttta gtctgaacaa
    19321 ctaaaaaact accttatctt tataatcctc aacacctttg ataaatagat cagacaagcc
    19381 aaaactacag gctaatttaa gtctattgat gctctaaagg ataaccaatg agagttcatt
    19441 gaactcagaa gacaatacgc tttaagacat caaaaaatag ccctgactgg tatatcacca
    19501 atcagcgcta ctttgcatat tctcttttag tttcttatct caaatatcag ttaatggaca
    19561 agcagtatct ggagaggtat catggaccgt aaagtctgta cctactgcta aatctgccat
    19621 agccagttga ttgaccatcg tcatatgcgc taactctttg atgttatttt ctttactcag
    19681 atgacctagg tatatttttt tggtattgta ccccaggctt ctaatcatgg ctcccgctcc
    19741 atcttcattt gataaatgtc ctaaatcaga taaaatacgc tgcttcaagc tccaaggata
    19801 agagcctgat ctcaaaattt caatatcatg attggattca atcaagtagc catccgcatt
    19861 ttcaataata cctgtcattc ggtcactgac ataacctgta tcagtcagca tcacaaacga
    19921 tttgttgtcc ttcataatgc ggtaaaactg aggatcaact gcatcgtgac taacgccaaa
    19981 actttcaatg tcaacatctc caaaggtcaa aactttatcc ctttggaaaa tatgtttttg
    20041 tgaggcatca agcttaccta gcatattgca ctcatccatc agctgccatg ttttttcatt
    20101 agcatagata tccaaatggt atttgcgggc cataacgcct acacccttaa tatggtcaga
    20161 gtgctcatgg gtaatcaaaa tagcatccaa atcctcaggt ttgcggtcaa tttcagcaag
    20221 aagactggta attttcttac cagtaagccc tgcatcaatc aataagcgtt ttttaggtgt
    20281 ttctaaataa aaacaatttc ctgtggaccc agatgctaaa atactatatt taaaaccact
    20341 ctcattcatt gattagtcta catcttcctc ccattcttca tagatggctg catctttttc
    20401 ataaggcaag acaatagtaa aggtcgatcc tttaccatag tcactcttag cccagataaa
    20461 gccatggtgc tgcttgatga tttctttagc aatggcaagg cctagaccgg tccctccttg
    20521 ggcacgactt cttgccttgt ctacacgata gaaccgatca aaaataagag gcaaatctgt
    20581 tttagggata cctagtcctt ggtctgaaat ggaaataatt aattgggtat ctgttgtttt
    20641 catacggact gtaatttttc caccatctgg agaatactta atggcattgt tcaaaatatt
    20701 ctcgataacc tgtgtcattt tatcattatc aatttcaagc cagacagagg taatagggta
    20761 atctcttaca atttcataga cttttcctgt acctgtatgc tgatttttaa ccaaatcaaa
    20821 tctgtttaaa atagaagtta taaaagcagt aaaattagtc atctctactg ctaattgggt
    20881 tacttgatta tcaatccgag acaggtttaa aagatctgaa atcatacgca tcatccgatt
    20941 agtttcatca agagaaactt ttatgaaact tggagcaata tcttctttaa gtgcaccttc
    21001 atcaagagcc tccaagtagg atttaaccga agttaaaggg gtccttaatt catgacttac
    21061 attagagaca aaaagacggc gttcacgttc ttctttttct tgttctgtgg tgtcatggag
    21121 caccacaacc aagcccgaaa taaaaccact ctctctccta ttcaacgcaa agcgcaagcg
    21181 taatgagaca aactcaccca tatcatttcg gctattaaca gttaccactg gtgttttgga
    21241 taccaaatca cgataggtat atgaagtatc accttctaac aaatctgtaa tgtttttctt
    21301 tagtgcctct tctttactta aatttaattg cttgcgagct gtctcgttaa tcatgatgat
    21361 tttaccagac cggtctgtag caagtacacc atctgacata taagccaaaa tacttgccaa
    21421 gcgatttttt tcttgggcaa gattttcatg cgtcaagcga aaaacatctg acaggtcatt
    21481 taactggtct gaaagctcca ttaactcaat gtctgctttt tcgtcgatta tatcagtata
    21541 gcgaccatta atcaagtctc ggattttatg gctcatcatc cgaataatac gtgcatttcg
    21601 gtaatcacgc accgcaagat ggataaagta aaaagcaaca aaaacaagta agataaggat
    21661 cgctaattca aatgtggata agtttccaat gatatctcta gtcataagat ttcatgtagt
    21721 acccaacacc acgtcttgtt aaaatatact caggacgact tggtgtgtct tcaatttttt
    21781 cacggagacg acgaacagtc acatcaaccg tgcgcacatc gccaaaataa tcatatcccc
    21841 aaacaatttc caataagtgt tctcgtgtca tcacctgacc catatggtta gctagatgat
    21901 gcaatagttc aaattcacga tgagtcaact ctacctcttg accatgtttt ttagcaacaa
    21961 acgcatctgg taaaatctgt aaattaccaa tggttagttc ctgtgtacct gaagaagcat
    22021 tttcttctgc aacagccgtt tcaatagttt cggtacgacg cagatgagcc ttgacacgcg
    22081 ccagcaattc ccgattagaa aagggcttgg tcacgtaatc atcagcccca atttcaagtc
    22141 caataacctt gtcaaactca ctatctttag ccgacaacat aataatcggg acatgactgg
    22201 ttttacgaat ttccttggct acttcaagac cgtccaactc agggagcatc aaatcaagaa
    22261 taattaaatc tggcttttct tcttcaaaaa ttgttaccgc ttcgcgtcca tcaaaagctg
    22321 taacaatgtc ataaccttct tttgtcaaat taaacttaat aatgtcagaa atcggttttt
    22381 catcatccac aataagtatt tttttcatgt ctatacctca gaaagttctt gtaattgata
    22441 ttacaatttg tgatttttgt ggttagtaaa aaatcacaaa actatatttt tctaaattat
    22501 ttctacctga ttataccaaa aatttagcct aattgacaat gacgactacc gttacaaata
    22561 gagtactttc taaaaccaac cctttatagg atgaatttgg cgtttgaatt gcttagcaga
    22621 ttttttgact ctggcaaaac tactcttgtt gtggtaagca aaaagtcctt tggcattaaa
    22681 ataagagaac ataaagtcat ctttttgagc tctaaaccac tggcgaaata ctctttttgg
    22741 cgatcgaaat cctttaaggg tgtctcttct aaactgagga tcgtgacggt taatcggatc
    22801 aacatctaaa tcccaatgtc taggaccatc tgtgccatag ttaaaagatg caccattgac
    22861 aattcctttt tcggtcacta tttctgcatc aacttcatta agaaaaaagc ctgtgctatc
    22921 tagaataaat tcggtatgaa accaaagaag tacttttata ttataggaaa cttcttgact
    22981 tggaaaaatg actttattat cttcaaatct tagtttatta tgtaacctgg cagaatccat
    23041 caaggtataa tctggtgctt gccgccacaa acaaggccct tttttagacc tcaaaaaaag
    23101 ggccagagct tgggcgtctg tcatctcaat cattttataa tggtttctga tagattgagc
    23161 ttgttgacta gagatgacat aacgaaattg atgcaaacgc ttttcaagct cacctgcttg
    23221 gcttagtgtt ttgccaggaa aagcttgatc aactaagcta gccaactctt tccaaaatat
    23281 atgatctggc aatagagatg gatggaatcg ggtgagtagc gtttgagttt catgcaactg
    23341 accacttagc tcaaatggca tctctaccaa atcaagaaga aacgttagta actgcttagc
    23401 tgattggttt tctttttcaa taggccatat tacccagaaa gttggagaac caagtcgatt
    23461 atcaatgata ggctctttag ctatagcacg aaatgcttgg tttgataaac ctgcgttttg
    23521 atagcatttc aaggcctgat agcgatctaa gatagcttgt ttcatggcct tctcctcatc
    23581 ttttttgacc atattataac acatctaaag ctgaatcgtc acttgtatct cgctataagc
    23641 aaaaagaaac ctgaagtcgt taactaagcc actgtttggg tattttattt aaaagaactt
    23701 ctcgattaat tttaccatta tcttttaaag gcaaacaatc aatcacaaga tagtacttgg
    23761 gaagttgtcc agagtttaaa taaagagcta aaaagtcttt aataggtgct aggcaatcct
    23821 tcttagtcaa aactaatact aatattaggg tttcgttttc tccttttcct atctttaaag
    23881 cgtgcgcttc tttgacattt ggcgcttggt gagcgagttc aactaggcta ggcaggtggc
    23941 atttcactcc tcgttgatta acccagtcat cttgtcgccc ttctaaaatt aaacccgctg
    24001 ggctcatttt tcctaagtct gagacactgt atggttgtga cattccttct acactataag
    24061 gagtctctac aaaaatttcc ttatctttga aactgataga cacatcagga aagggctgtc
    24121 ctaccaaacc attaattttg acagcagctc tgccattaca ccacgttata aaagataatt
    24181 cactagcccc gtagaaaatg acaatttcaa gctgaggaaa ttttttgtaa taatgtctta
    24241 gtaattcttg tgatatcatt tgcgaagagg tcaataagtg agtcgcagtc atgttgttct
    24301 tagtcaaata aggtagcaag cgatttaggt aagtcggtaa aaggtaaagg tgactcacct
    24361 tttttgcttg ccataagctt aaccacgttt tcaaagacag cttttggctt aaaaccagac
    24421 atcccccggc ccatagttga gctaatgcta agttaagatt gccagtaaaa ctaaaactac
    24481 catgtaagaa tagacaacta ttaccagtca taccaaacac cttattttga taatcaaaaa
    24541 gtctcgtcca agttgataga caacgccaaa ataattttgc tttgccagtt gttcccgaac
    24601 tcaaaacagc aaaatcagct tttttaagaa gctcactatc gacgtgtttt atttgctgct
    24661 gaaatgtacc tgagatatta gggtgtaaaa tgataggaca actgccttct tttaatcctt
    24721 gtaaaaaaga gagtaactga ttaagatagc gactatgact gatgatatat ggtacactgt
    24781 cttttattgt ctgatccttt attaaaaccg cttgccatag ctcttgataa gtcaagctta
    24841 tctgatcggc tacgatagct tttttatttg ggcattgctt tgcccaatat tctagctttg
    24901 tcagcatgac taaactcctt atgatatttt agtaaaacag caaacccttg gccaccagct
    24961 gctgctatag cagctattcc atagcgtcca tttttaatct ctaaagccct cattaagtgc
    25021 aatattataa tggctgctga ggcaccatag ggatgaccat aagctaatgc accaccaaat
    25081 atattatagc ggtccaataa atctggataa tgggtttcaa atagaccatc aataacggca
    25141 aaggcttcgt tccattcaat cgctgtcata tctgccatcc ctagaccata tttttccaaa
    25201 aggacttgac tagccttaat caccattaaa gggctacgct gtgggtctcc tgctacttct
    25261 accacatcaa tcagtttaaa agctgaaggc tgactactta gctgtaaaaa ggcagcagca
    25321 tcatgggtga ggcaggcatt ggctgcacta atcacgtgat cttctcctaa gatagggggt
    25381 acctttgaca acaccttact tgacaagcgc ggtcgaatac cttgatcact ggctcctggc
    25441 aggtctagaa taagatcagc taacagggct tgctcctggc aataactagc cttttgatga
    25501 cttctcaatg tccagtgatt caaatactcc tttgtaaagc catgctctct tgccactcgt
    25561 tctgcccctt caatcatcgc aaaagggctg atactatctg gagaaaactg agctaccttg
    25621 taggctcctt ggcgccaatc agctgaagca tataccgatt caggttgtaa ggagctgctt
    25681 tcaatccctc ccactaaaag gttgcttgcc atacctgcct tgattttagc ataacccacg
    25741 gaaagagctg caccagctga tgcacactgc atatcaaccg tcaaagcaga gacagattct
    25801 cctaaatgag aatacagggt catcaagcgc ccaatattac cacccgttcc gacggtattg
    25861 ccacaaatca cttggtcaat gggaactgga tacttatttt gtaaagcatt gatgagcttt
    25921 gctccaagga tttctggttg ttctttagca aattgtttcc ctactaaacc gataggggtt
    25981 ctaaggcctg cagcaatata aacatccgtc atggtcataa tctcctttag ctactaattt
    26041 accagcctga aacaggccaa tggctctacc tttcatcatc aattggatag agctatctaa
    26101 aaccactggc gcataaaagc gcaaatgtaa ttgacgataa tcgatagcta acttatcact
    26161 cacctgctcg agtaagaatg ctccgggtaa aacataaggc acttctcggt gaataggttt
    26221 ttgatccccg gtatcctcta gaaagtgagc gagggcagct tgactgatat ttattgtctg
    26281 atcatcattt gctaaaaact tattagcctt ttcttctaat tgattactat tggtggattc
    26341 tgataaccac tgaaccggct gcttcttcaa gaatcggacc tcaagcgtca gccctgattc
    26401 actcaacctt attttccgga aacgttgggt atccgtgagc acttgatttt catataattg
    26461 cgcagctttt tctaaggtca tgtcaaccac caggctgttc tttggtaaat cttggttgca
    26521 cttaatcatg gtacttagta gtcttctcat tgtcaccctc atttttcaat cacgttaact
    26581 ttattatact gaaagctccg atccaagaaa agggaaaatc tgtaaaagaa cacttcttag
    26641 ccaccaaaaa aagttgagtc ctagacccaa ctttttttgg ttcattacat catatttaaa
    26701 atcacttgat aaatcaaggc acctacgacc ccaccaagga ttggacctaa aactggaatc
    26761 caagcgtatg accagtcaga atctccttta tttgggattg gaagtaaggc atgcatgata
    26821 cgtggcccaa ggtcacgcgc tgggttgatg gcataaccag tggttgctcc aagtgaaaaa
    26881 ccaactgcca taaccacaaa accaacaata atcggaccaa aaccagcagc tactttatta
    26941 gggccaatgg ccattaccgt aatcactaaa acagctgttc ctaaagcttc gccaaaaagg
    27001 tttgaccaag tgtggcgaat agctggccca gttgagaaac aagctaaaat cgtaccagca
    27061 tctttggttt cattccaatg tgggtagtaa tgcaagtaga gaactaaggc tccaagcatt
    27121 gctccaagaa attgagccac aagataagtc actacctgag accatggcaa tgagccaatg
    27181 gctgccatag cgagtgtcac ggctgggttt aagtgggcac cactcatgaa accactaata
    27241 taaaccgcaa cggttacagc aattccccaa cccaaaacaa tagcaatcca gccactattt
    27301 tgagctttgg ttttattcaa gatacaagca gaaaccacac cgtctcctaa taaaaccaaa
    27361 ataaacgttc ctaacagttc accggtaaaa ttcatgataa tctccttgct atttatttat
    27421 tgatagctaa ctcttctaac tgacttaaaa tagcatcctt gtccgcgcca gcctgaataa
    27481 gagctgctgc tgtgtaagcc ccttcgacaa tgggaaccac attcaaggta atgatcttgt
    27541 cagaaaaatc tgaaaccatt tcgatattca tgcgggcaga tccaagatca aagaaagcca
    27601 ataagtcatc cttaggattg gcgtcaacga tagcctgcac ttggtcaaaa ctggtgccga
    27661 taccaccatc ttctgtacca ccgacatagg tgatggcaac atctgtcgcc acctctgaaa
    27721 tcaggtcgac aactccttga gcaatatttt tagaatgcga tacaataata attcctaaat
    27781 ctgacattaa accacctctg cttccaacat ggcttcaaat aagagtcctg atgagaagga
    27841 acctggatca atatgaccca ctgagcgttc tcctacataa gaagcgcgtc ctttagttgc
    27901 ctggatgtct ttggtagcta aaacagcctc ttcaaccaca tccttggtta acccgtcatt
    27961 tttcaaggct tcaatcacag gaatccaaac atccaccatg gttttctcac ctttttctgc
    28021 cttaccacgt ttttgaatca tgtccaatcc agcctgcaaa gcatctgcca aactgctatc
    28081 ctcactagct tttgaaagcc ccataaaggc agaaccatac aatgggcctg aagctccacc
    28141 aactttgcct agcaactgca tagcaacgac cttaaagaca tccgctgcgc tcgcaaattc
    28201 tttaccggca agattttcca tgacagcaga catcccgcgc gccatattgc caccgtgatc
    28261 accatctccg ataggcgtat ccaattgact taaataatcc ttattcactt gaattttatc
    28321 attaaataag gtcatccatt tgattgcatc ttgtgcttgc atgatttcct ccttaccaag
    28381 ctggtgtgat aacatctgat tgaagagctt ctgtccattc atccttgtca agtttgatca
    28441 aggtcaaaga caaaccagcc atatcaatag acgtcatata gtcaccaatt ttcttgaagc
    28501 tgactgtgac atctttttct gccaagagtt ttgccacatc attcgcaaaa acgtattgtt
    28561 ccattaatgg tgtagctccc aaaccattga ccaagacgcc ataatgttgt cctgcgctca
    28621 tgtcaaagct atctgccaat ttagttacca actcttgagc taatactgat gatgattgta
    28681 atttttcttt tttgtagcct ggttcaccgt gaataccaac accgtattca aactcatcat
    28741 cttcaagcac aaaaccaggt ttgccaactt caggaacagt tgctccagaa agagctagac
    28801 caatagtttt aatatttagg accaattcat cagcaagagc tttaatatcc gctaatgatt
    28861 tgccctcacg cgcagcatgt cccaaaatct tgtgaacaag aatggttccc gcaacgccac
    28921 gacgaccttg agtgtagagg ctattctcaa ccgcaatatc atcatcaacg acaacactgg
    28981 caacatcaat gccttccatt tctgctaatt cttgggccat ttcaaagttc ataatgtcac
    29041 ctgaataatt tttgatgacc atgaagacac cagcaccttc atcagctgct ttgatagctt
    29101 ctaaaatttg atctggagtt ggggaagtaa agactgcacc acagatagct gctgacaaca
    29161 tgccttcacc aacaaaacca gcatgagatg gctcatgtcc agaaccacca cctgaaataa
    29221 gggctacttt tcccgtcttc tctgctttac gaacaatcac atcataacca tctaggcgtt
    29281 ccactaagtc atcatgcata taagctaaac cttgcaacat atcgtccaca atctgagtgg
    29341 catcattcat aatttttttc atggatcttc ctccgatttt ttgtttacgc tttcattata
    29401 aaatagcccc tcccaaaacg taagggacaa atcctcagat ttgtcccttt tctttctaaa
    29461 atgcctttga taaggtataa tggcagaaga tatttcatat taaaggatta cttatggcaa
    29521 cttctctcat caccaagaaa aaaattgcca aagcttttaa aaagcaacta gcagtgaaaa
    29581 gctttgataa aatttctgtc gttgatatta tggatcaggc ccaaatcagg cggcaaacct
    29641 tctacaatca ttttctagat aagtatgaac tgttagactg gatttttgag actgaacttc
    29701 aggaacaggt cacacacaat ctcaattaca tcagtggctt tcaactgtta gacgagttgc
    29761 tcttttattt tgaacgcaac aagacgtttt atgcccaact atttgatatc aaagggcaaa
    29821 atgatttttc cagctacttt gtggactact gtcaggtctt aatggctaaa atcatttctg
    29881 aataccaaag tcaagaaatg agccaatctg atgatgctga ttaccttgct tttttaaccc
    29941 attatcatgc tagggcacta gcagatatga ttaaaggtta tgttagtcag agtgaaccta
    30001 aaccttgtct tacctatctc aagcagctta tcttaaccag cattcattaa acgaggaaaa
    30061 cgtcatggta accatattaa atcaaacaca aacgcttatt tcccaatata tagcaagtgt
    30121 attagcagcc catccccacc tagtccagtt acaggatttg cctattattt ataataggca
    30181 tctcgatgat caactcatcc caattctatc cggaggagga tccggacacg aacctgctca
    30241 ttccggcttc gttggtgatg gtatgctgtc agctgccatc tatggcgata tttttactcc
    30301 cccaactgcc acagacatct tagaagccct gcgatttcta gataaaggta agggggtctt
    30361 tgtcatta
//
LOCUS       DAXMQE010000020        29391 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.020, whole genome shotgun sequence.
ACCESSION   DAXMQE010000020 DAXMQE010000000
VERSION     DAXMQE010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29391)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29391)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29391
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.020"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            <1..854
                     /locus_tag="ACF4ZO_001104"
     CDS             <1..854
                     /locus_tag="ACF4ZO_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="gp58-like family protein"
                     /protein_id="HFD5486655.1"
                     /translation="IQKAGGINAKMSGNEIISAINLNSYGVTIAGKHIALDGNTTVNG
                     TFTTKIAEAIKIRADQIIAGTIDAARIRVINLNASSIVGLDANFIKAKIGYAITDLLE
                     GKVIKARNGAMLIDLNTAKMDFNSDATINFNSKNNALVRKDGTHTAFVHFSNATPKGY
                     TGSALYASIGITSSGDGVNSASSGRFAGLRSFRYATGYNHTAAVDQTEIYGDNVLVVD
                     DFNITRGFKFRPDKMQKMLDMNDLYAAVVALGRCWGHLANVGWNTAHSNFTSAVNGEL
                     NNYITKI"
     gene            866..1303
                     /locus_tag="ACF4ZO_001105"
     CDS             866..1303
                     /locus_tag="ACF4ZO_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1617 family protein"
                     /protein_id="HFD5486656.1"
                     /translation="MQLTIKNKDLNTLYCVLDKIKVTNMRANRGRAKLLAKVVDKFKE
                     YAKDEGDLIDLYAQKDKDGKFVIDEHKNIKLADPAKLDEFNGLLNELADEEIVIKGGE
                     YSKRFIDFLNFLEECEDEFTSSEIILIDNILEQFEESKKGEKP"
     gene            1300..1917
                     /locus_tag="ACF4ZO_001106"
     CDS             1300..1917
                     /locus_tag="ACF4ZO_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1366 domain-containing protein"
                     /protein_id="HFD5486657.1"
                     /translation="MRNWKVTGKYPQFDSTVAVASTHIIITAEDGSVISQLVKQDLIS
                     TNDTEIIKATLEEFKKSEYVEIAMGEAVQKVDDLEKISQETAKTAKTAQTAAGLAKVS
                     AERTQRMINLQTIHMLTSGGKIDSDIYKGMLELIEPAKKGEYQAYDVFTVVDSTKEED
                     GEAGEGNLVFVHVNEPFTYEAQTLEELESEAKVTVIKYADLVKQD"
     gene            1927..2199
                     /locus_tag="ACF4ZO_001107"
     CDS             1927..2199
                     /locus_tag="ACF4ZO_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486658.1"
                     /translation="MATELIFGVGGFILAIVTTYNIFNAKSIKHATDITLLQSEVEHL
                     KIVTRQNARRLEEHDEQNKTLITMTEQIKNLNREVRELKDIMKGEA"
     gene            2196..2423
                     /locus_tag="ACF4ZO_001108"
     CDS             2196..2423
                     /locus_tag="ACF4ZO_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140911 - pore-forming activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HFD5486659.1"
                     /translation="MINLKLRLQNKVTLMAILGAIFLLAQQLGIKLPSNIADIANTAV
                     TLLVLLGVVTDPTTKGLSDSEQALTYHEPKQ"
     gene            2539..3741
                     /locus_tag="ACF4ZO_001109"
     CDS             2539..3741
                     /locus_tag="ACF4ZO_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HFD5486660.1"
                     /translation="MTFLDKIKQGCLDGWTKYKILPSLTAAQAILESGWGKHAPHNAL
                     FGIKADASWTGKSFDTKTQEEYQPGIVTDIVDRFRAYDSWTDSIIDHGKFLNDNPRYK
                     AVIGETDYKKACYAIKAAGYATASSYVELLIQLIEENDLQSWDREALKNNKEETMTTA
                     NEIVQYCVNLANSGMGVDKDGAHGTQCCDLPCFVAKNWFGVDLWGNAIDLLDSASAQG
                     WEVHRMPTEANPKAGATFVQSVPYHQFGHTGIVIEDSDGYTMRTVEQNIDGNADALYV
                     GAPARFNTRDFTGVVGWFYPPYQGDTVTQPVSTEPQTSDTIVETAKTGTFTLDVAEIN
                     IRRWPSLASEVVGIYKQGDTVSFDSEGYANGYYWISYVGGLGMRDYLAIGQTDKDGNR
                     ISIWGKLN"
     gene            4063..4578
                     /locus_tag="ACF4ZO_001110"
     CDS             4063..4578
                     /locus_tag="ACF4ZO_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486661.1"
                     /translation="MKSKKLVFGQIDLNMCRDFDLVQALDYDFKEKKLYNKGRGFAIV
                     LVSIQNLTFAIPLRSNIPKKYQLKYKLRDSKKYGCVEGLDIGKALVVEDPKYILNRTF
                     KLREQVDYFKIVDNDILIVNKLIKAIIDYNQAVANSDQHKLTDPKRFKFSTFPNYTDR
                     LKSITDADYLR"
     gene            complement(4692..5678)
                     /locus_tag="ACF4ZO_001111"
     CDS             complement(4692..5678)
                     /locus_tag="ACF4ZO_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HFD5486662.1"
                     /translation="MDMSKKLRNSLARIVVAAFASFAVMAIPTYHHSTVLAKTVSVNQ
                     TYGEYKDYYTVIGESNIDQSAFPKIYKTTERVYKGQGTSEKRVTVSDVVYNPLDGYKR
                     STGAYGVVTKDMIDMSKGYREKWETNPEPSGWFRFYNRADNEEISEKEYDSRRTKSYK
                     VTNNVPVVLTTLKGKQYNSHLFVRSHLFADSLGGKSIRKNAITGTQMQNVGTRKGGMQ
                     YIEKKVLSHITKNPDVYVFYSAIPEYQGTELLARSVLVSALSSDGVINETVRVFNTAD
                     GFNINYEKGGLLTESPVSEIDNIEDSTTDEIENSVDDSEEIVYNDTTTEEEN"
     gene            5911..6093
                     /locus_tag="ACF4ZO_001112"
     CDS             5911..6093
                     /locus_tag="ACF4ZO_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Paratox"
                     /protein_id="HFD5486663.1"
                     /translation="MLTYDEFKQAIDDGYITGDTVAIVRKNGQIFDYALPNEEVRNGE
                     VVTYENVEEVLRELDK"
     gene            6332..7339
                     /gene="plsX"
                     /locus_tag="ACF4ZO_001113"
     CDS             6332..7339
                     /gene="plsX"
                     /locus_tag="ACF4ZO_001113"
                     /EC_number="2.3.1.274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043811 - phosphate:acyl-[acyl carrier
                     protein] acyltransferase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HFD5486664.1"
                     /translation="MKRIAIDAMGGDNAPKAIVEGVNQVIEAFSDIEIQLYGDQTKIN
                     SYLIQSDRVAIIHTDEKIMSDDEPAKAVRRKKKASMVLAAKAVKEGKADAIISAGNTG
                     ALLAVGLFVVGRIKGVDRPGLLSTIPTVTGLGFDMLDLGANAENTVKHLHQYAILGSF
                     YAKNVRGIANPRVGLLNNGTEETKGDPLRKATYELLTADNTISFVGNVEARELMSGVA
                     DVIVSDGFTGNAVLKSIEGTGISIMGQLKQIINSGGIKTKIGASLLKSSLYEMKKTLD
                     YSSAGGAVLFGLKAPVVKSHGSSDVKAIFSTIKQVRTMLDTNVVGQLVEEFAKETQVN
                     D"
     gene            7332..7574
                     /locus_tag="ACF4ZO_001114"
     CDS             7332..7574
                     /locus_tag="ACF4ZO_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantetheine-binding protein"
                     /protein_id="HFD5486665.1"
                     /translation="MTRQEIFERLINLIQKQRSYLSVAITEQTHLKNDLAVDSIELVE
                     FIINVEDEFHIAIPDEDVEDMVFMEDVLDYLVQRLT"
     gene            7726..8430
                     /gene="purC"
                     /locus_tag="ACF4ZO_001115"
     CDS             7726..8430
                     /gene="purC"
                     /locus_tag="ACF4ZO_001115"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004639 -
                     phosphoribosylaminoimidazolesuccinocarboxamide synthase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HFD5486666.1"
                     /translation="MTNQLIYKGKAKDIYSTKDENVIRTVYKDQATMLNGARKEAIDG
                     KGALNNQISSLIFEKLNKAGVVTHYIEQISKNEQLNKKVDIIPLEVVLRNVTAGSFSK
                     RFGVEEGRVLETPIVEFYYKNDDLNDPFINDEHVKFLGIVNDEEIAYLKGETRRINEL
                     LKGWFAQIGLNLIDFKLEFGFDQEGTIILADELSPDNCRLWDKNGNHMDKDVFRRDLG
                     NLTDVYQVVLEKLIAL"
     gene            8554..12279
                     /locus_tag="ACF4ZO_001116"
     CDS             8554..12279
                     /locus_tag="ACF4ZO_001116"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004642 -
                     phosphoribosylformylglycinamidine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HFD5486667.1"
                     /translation="MNKRIFVEKKADFGIKSASLVKELTHNLQLTSLKDLRIVQVYDV
                     FNLAEDLLARAEKHIFSEQVTDRLLTEAEITAELDKVAFFAIEALPGQFDQRAASSQE
                     ALLLFGSDSQVKVNTAELYLINKDIAEAELEAVKNYLLNPVDSRFKDITLPLEEQAFS
                     VSDKTIPNLDFFENYKADDFAAYKAEQGLAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKNIDFSASKFQKQLQTTYDKYIAMRDELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITTPIAETRTGKLPQQVISKTAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKENVVREKPEAGDVVILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRDGEVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLDKVPLKYQGLNGTEIAISESQERMSVVVRPSDVDAFIA
                     ACNKENIDAVVVATVTEKPNLVMTWNGETIVDLERRFLDTNGVRVVVDVKFVDKDLTV
                     PEARTTSAETLEADTLKVLSDLNHASQKGLQTIFDSSVGRSTVNHPIGGRYQITPTES
                     SVQKLPVQHGVTRTASVMAQGYNPYIAEWSPYHGAAYAVIEATARLVATGADWSRARF
                     SYQEYFERMDKQAERFGQPVSALLGSIEAQIQLGLPSIGGKDSMSGTFEDLTVPPTLV
                     AFGVTTADIRKVLSPEFKAAGENIYYIPGQAISEDIDFDLIKANFSQFEAIQAQHKIT
                     AASAAKYGSVLESLALMTFGNRIGASVEIAELDSSLTAQLGGFVFTSAEEIADAVKIG
                     QTQADFTVTVNGNDLAGASLLAAFEGKLEEVYPTEFEQADALEEVPAVVSDTVIKAKE
                     TIEKPVVYIPVFPGTNSEYDSAKAFEQVGASVNLVPFVTLNEVAIAESVDTMVANIAK
                     ANIIFFAGGFSAADEPDGSAKFIVNILLNEKVRAAIDSFIEKGSLIIGICNGFQALVK
                     SGLLPYGNFEEAGETSPTLFYNDANQHVAKMVETRIANTNSPWLAGVEVGDIHAIPVS
                     HGEGKFVVSASEFAELRDNGQIWSQYVDFDGQPSMDSKYNPNGSVNAIEGITSKNGQI
                     IGKMGHSERWEDGLFQNIPGNKDQTLFASAVKYFTGK"
     gene            12513..13967
                     /gene="purF"
                     /locus_tag="ACF4ZO_001117"
     CDS             12513..13967
                     /gene="purF"
                     /locus_tag="ACF4ZO_001117"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004044 - amidophosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HFD5486668.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPQAAQVTYFGLHSLQHRGQEGAGI
                     VSNDNGKLYGYRNVGLLSEVFKNQSELDNLTGNAAIGHVRYATAGSADIRNIQPFLYK
                     FHDGQFALCHNGNLTNAISLRKELEKQGAIFNASSDTEILMHLIRRSHNSSFMGKVKE
                     ALNTVKGGFAYLLMTENKLIAALDPNAFRPLSIGQMQNGAWVISSETCAFEVVGAKWV
                     RDVEPGEVILIDDRGIQCDRYTDETQLAICSMEYVYFARPDSTIHGVNVHTARKNMGK
                     RLAQEFKQDADIVIGVPNSSLSAAMGFAEESGLPNEMGLVKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMIDDSIVRGTTSRRIVGLLREAGASEVHVAIASPELKY
                     PCFYGIDIQTRRELISANHAVDEVCDIIGADSLTYLSLDGLIESIGLETKAPNGGLCV
                     AYFDGHYPTPLYDYEEEYLRSLEEKTSFYIQKVK"
     gene            13995..15017
                     /gene="purM"
                     /locus_tag="ACF4ZO_001118"
     CDS             13995..15017
                     /gene="purM"
                     /locus_tag="ACF4ZO_001118"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004641 -
                     phosphoribosylformylglycinamidine cyclo-ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HFD5486669.1"
                     /translation="MSEKNAYAKSGVDVEAGYEVVERIKKHVARTERAGVMGVLGGFG
                     GMFDLSKTGVKEPVLVSGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYIATGKNNPVKLEEVVSGVAEGCVQAGVALIGGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQIIDGSKVKEGDILLGLASSGIHSNGYSLVRRVFADYTGKELLPELEGKRLK
                     DVLLEPTRIYVKAALPLIKEELVNGIGHITGGGFIENVPRMFADDLAAEIDEDKVPVL
                     PIFKALEKYGDIKHEEMFEIFNMGVGLMLAVSPENVNRVKDLLDEPVYEIGRIIKKAD
                     DSVVIK"
     gene            15185..15739
                     /gene="purN"
                     /locus_tag="ACF4ZO_001119"
     CDS             15185..15739
                     /gene="purN"
                     /locus_tag="ACF4ZO_001119"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004644 - phosphoribosylglycinamide
                     formyltransferase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HFD5486670.1"
                     /translation="MKIAVFASGNGSNFQVIAEQFPVSFVFSDHRDAYVLERAQNLAI
                     PSFAFELKEFENKAAYEQAIVDLLDKHEIDLVCLAGYMKIVGETLLLAYEGRIINIHP
                     AYLPEFPGAHGIEDAWEAGVDQSGVTIHWVDSGVDTGQVIQQVRVPRLADDSLESFET
                     RIHETEYQLYPAVLDSLGVERKVI"
     gene            15923..17470
                     /gene="purH"
                     /locus_tag="ACF4ZO_001120"
     CDS             15923..17470
                     /gene="purH"
                     /locus_tag="ACF4ZO_001120"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0003937 - IMP cyclohydrolase activity
                     [Evidence IEA];
                     GO_function: GO:0004643 -
                     phosphoribosylaminoimidazolecarboxamide formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HFD5486671.1"
                     /translation="MTKRALISVSDKSGIIDFAKELKNLGWDIISTGGTKVALDNAGV
                     ETIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDVDSHLQAAKDNNIELIDLVVVNL
                     YPFKETILRPDVTYDLAVENIDIGGPSMLRSAAKNHASVTVVVDPADYATVLGELADA
                     GQTTFETRQRLAAKVFRHIAAYDALIAEYFTAQVGEAKPEKLTITYDLKQAMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDVDAAIRIIRDFKDRPTVVALKHM
                     NPCGIGQADDIETAWDYAYEADPVSIFGGIVVLNREVDAATAKKMHPIFLEIIIAPSY
                     SEEALAILTNKKKNLRILELPFDAQAASEVEAEYTGVVGGLLVQNQDVVAENPSDWQV
                     VTDRQPTEQEATALEFAWKAIKYVKSNGIIITNDHMTLGLGAGQTNRVGSVKIAIEQA
                     KDHLDGAVLASDAFFPFADNIEEVAAAGVKAIIQPGGSVRDQDSIDAANKHGLTMIFT
                     GVRHFRH"
     gene            complement(17529..18653)
                     /locus_tag="ACF4ZO_001121"
     CDS             complement(17529..18653)
                     /locus_tag="ACF4ZO_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HFD5486672.1"
                     /translation="MKKFHRFLVSGVILLGFNGLVPTMPSTLISQQENLVHAAVLGDN
                     YPSKWKKGNGIDSWNMYIRQCTSFAAFRLSSANGFQLPKGYGNACTWGHIAKNQGYPV
                     NKTPSIGAIAWFDKNAYQSNAAYGHVAWVADIRGDTVTIEEYNYNAGQGPERYHKRQI
                     PKSQVSGYIHFKDLSSQTSHSYPRQLKHISQASFDPSGTYHFTTRLPVKGQTSIDSPD
                     LAYYEAGQSVYYDKVVAAGGYTWLSYLSFSGNRRYIPIKEPAQSVVQNDNTKPSIEVG
                     DTVTFPGVFRVDQLVNNLIVNKELAGGDPTPLNWIDPTPLDETDNQGKVLGDQILRVG
                     EYFTVTGSYKVLKIDQPSNGIYVQIGSRGTWVNADKANKL"
     gene            18906..20171
                     /gene="purD"
                     /locus_tag="ACF4ZO_001122"
     CDS             18906..20171
                     /gene="purD"
                     /locus_tag="ACF4ZO_001122"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004637 - phosphoribosylamine-glycine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HFD5486673.1"
                     /translation="MKLLVVGSGGREHAIAKKLLASKGVDQVFVAPGNDGMTLDGLDL
                     VNIVVSEHSRLIAFAKENEISWAFIGPDDALAAGIVDDFNSAGLRAFGPTKAAAELEW
                     SKDFAKEIMVKYNVPTAAYGTFSDFEKAKAYIEEQGAPIVVKADGLALGKGVVVAETV
                     EQAVEAAQEMLLDNKFGDSGARVVIEEFLDGEEFSLFAFVNGDKFYIMPTAQDHKRAF
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVETIVRPVLEGMVAEGRPYLGVLYVGLILT
                     ADGPKVIEFNSRFGDPETQIILPRLTSDFAQNIDDIMMGIEPYITWQNDGVTLGVVVA
                     SEGYPLDYEKGVPLPEKTDGDIITYYAGAKFAENSELLLSNGGRVYMLVTTEDSVKAG
                     QDKIYTQLAQQDTTGLFYRNDIGNKAIKE"
     gene            20449..20940
                     /gene="purE"
                     /locus_tag="ACF4ZO_001123"
     CDS             20449..20940
                     /gene="purE"
                     /locus_tag="ACF4ZO_001123"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009320 - phosphoribosylaminoimidazole
                     carboxylase complex [Evidence IEA];
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HFD5486674.1"
                     /translation="MKTPIISIIMGSKSDWATMQKTAEILDNFGIAYEKKVVSAHRTP
                     DLMFKHAEEARGRGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRVLSGLDSLYS
                     IVQMPGGVPVATMAIGEAGATNAALTALRILSIEDQNLADALAHFHEEQGKIAEESSN
                     ELI"
     gene            20927..22000
                     /gene="purK"
                     /locus_tag="ACF4ZO_001124"
     CDS             20927..22000
                     /gene="purK"
                     /locus_tag="ACF4ZO_001124"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HFD5486675.1"
                     /translation="MNSFKTIGIIGGGQLGQMMAIAAIYMGHKVITLDPTNDCPASRV
                     SEVIVAPYDDVEALGQLAACCDVLTYEFENVNADGLDAVVSACQLPQGTDLLRISQNR
                     IFEKDFLANKAGVTVAPYKVVTSSLDLEGLDFTKTYVLKTATGGYDGHGQKVIRSAED
                     LPEAQQLANSAQCVLEEFVNFDLEISVIVSGNGEDVTVFPVQENIHCNNILSKTIVPA
                     RISDQLADKAKKMAVQIAKKLQLSGTLCVEMFATADDIIINEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGQPLPPIKLHAPAVMLNVLGQHVQQAIDYVAQNPSAHLHMYGKLE
                     AKHNRKMGHVTLFAEDADEVEEF"
     gene            22021..23361
                     /locus_tag="ACF4ZO_001125"
     CDS             22021..23361
                     /locus_tag="ACF4ZO_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486676.1"
                     /translation="MELREFKAWLLKNHFEEDELYKESIKCYQVEAYKAAYIFSYLAN
                     HKFIAKLAIDYSGVSSNFMSKCPDDEVRKSSWQKRVNSLKNEDEWEQTVNEKLIQAWE
                     DDNVFKLPFKIKEKYSLMRVLRNNAAHAKDCRISESTVLELWNEIEYIYPYFVINGTI
                     DAWMEDLEKLVRYSNSSIESQNQLQNKFGDFSTENKTLIVKKIIQKYLVDSEWDETYP
                     DIVMNFLLYIFQESNYINQIGKDLTEKEELYLSIGTGIYHFQAEAIDIYSQFEESLSD
                     YTFRYFCEEFSDNFWKFIDSMDSEVNKENLTATSLEILKKNSAILVNAEFNESRFLSD
                     NSLFFKSVLDKIKHLYYYTMHHTGQRHHNTNTFDYSKFNSYIPYINYIFYRISSNPGL
                     KEDEKVIDFVKRCNNLISSDYSAESWYSERQMQDVIKKINEKYTILEDSGRESD"
     gene            23577..24869
                     /gene="purB"
                     /locus_tag="ACF4ZO_001126"
     CDS             23577..24869
                     /gene="purB"
                     /locus_tag="ACF4ZO_001126"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004018 - N6-(1,2-dicarboxyethyl)AMP
                     AMP-lyase (fumarate-forming) activity [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HFD5486677.1"
                     /translation="MIERYSRPEMAAIWTEENKYRAWLEVEILADEAWAELGEIPKED
                     VAKIREKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIVADKAREHKMTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRPQEISTQVLPRDL
                     HAEYFAVLASIATSVERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMVTAYENVSLWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMMRNMESTFGLIYSQRVMLKLIEKGMTREEAYDLVQPKTAYSWDNQVDFKPL
                     LEEDTKVTSCLTQEEIDELFNPIYYTKRVDDIFNRLGI"
     gene            25000..25911
                     /gene="rgg4"
                     /locus_tag="ACF4ZO_001127"
     CDS             25000..25911
                     /gene="rgg4"
                     /locus_tag="ACF4ZO_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Rgg4/ComR"
                     /protein_id="HFD5486678.1"
                     /translation="MLEHFGGKVKVLRLEKRISREDLCGDESELSVRQLARIELGQSI
                     PSLSKVIFIAKALNVSVGYLTDGADLELPKRYKELKYLILRTPTYMDDGKLQVREEQF
                     DEIFEDYYDKLPEEEKIIIDCLQATLDTLLSENTNFGIDLLQEYFNQIKTKVRFRQND
                     LILLELYLAYLDIEGMDGQYSDKIFYDSLLDNLSEQFEQFELDELFIVNKIIIDISSL
                     SLKNNRLDNLEKAIEMSQKIMAKIQDWNRMPILKLIEWKYFLIKQKDIIKAEQSFMKA
                     CLFAQMTADQYLENKLIQEWEKDVKSY"
     gene            25995..26090
                     /locus_tag="ACF4ZO_001128"
     CDS             25995..26090
                     /locus_tag="ACF4ZO_001128"
                     /inference="COORDINATES: protein motif:HMM:NF038244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system DWW-type pheromone"
                     /protein_id="HFD5486679.1"
                     /translation="MLKKYKYYFIFAALLSFKVVQELSAVDWWRL"
     gene            26137..27135
                     /gene="ruvB"
                     /locus_tag="ACF4ZO_001129"
     CDS             26137..27135
                     /gene="ruvB"
                     /locus_tag="ACF4ZO_001129"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_023079556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HFD5486680.1"
                     /translation="MARILDNNVMGNEEFSDRTLRPQYLHEYIGQDKVKEQFAIFIEA
                     AKRRDESLDHVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPAVEKAGDLVAILNELE
                     PGDILFIDEIHRMPMSVEEVLYSAMEDFYIDIMIGAGDTSRSIHLDLPPFTLIGATTR
                     AGMLSNPLRARFGITGHMEYYQEKDLTEIVERTATIFEIKIDHEAARKLACRSRGTPR
                     IANRLLKRVRDYAQIIGDGIITAQITDRALTMLDVDREGLDYIDQKILRTMIEMYQGG
                     PVGLGTLSVNIAEERNTVEEMYEPYLIQKGFLMRTRTGRVATQKAYRHLGYPYQNT"
     gene            27273..27710
                     /locus_tag="ACF4ZO_001130"
     CDS             27273..27710
                     /locus_tag="ACF4ZO_001130"
                     /EC_number="3.1.3.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight
                     protein-tyrosine-phosphatase"
                     /protein_id="HFD5486681.1"
                     /translation="MKKVCFVCLGNICRSPMAEFVMKSIVSSDVMMIESRATSDWEHG
                     NPIHSGTQSILKTYQINYDITKCSKQITITDFNTFDYIIGMDSDNVKNLKEMSQHQWD
                     SKIYLFREGGVPDPWYTNDFEETYQLVRKGCQDWLSRLMSKEY"
     gene            27733..28134
                     /locus_tag="ACF4ZO_001131"
     CDS             27733..28134
                     /locus_tag="ACF4ZO_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MORN repeat-containing protein"
                     /protein_id="HFD5486682.1"
                     /translation="MIDMQDIVKKWSITRAKLEIVSVIVILVCAISVFSVRISNKTSL
                     TYDKGRMHYTGYVINHKMNGEGKLVYPNGDIYEGTFKNGLFEGKGTFTAKTGWLYNGE
                     FHKGQANGKGVLKAKNNKVYKGIFKQGIFQK"
     gene            28131..>29391
                     /locus_tag="ACF4ZO_001132"
     CDS             28131..>29391
                     /locus_tag="ACF4ZO_001132"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HFD5486683.1"
                     /translation="MRIKWFSFVRVTGLLLVLLYHFFKNVFPGGFIGVDIFFTFSGYL
                     ITALLIDEYTKKESIDIIGFLKRRFYRIVPPLVLMILLTIPFTFLIKKDFIANIGSQI
                     TAVLGFTTNIYEILTGSSYESQFIPHLFVHTWSLAIEVHFYLLWGVFVWLLARRKETQ
                     KQLRGLLFLISLGIFAISFLSMFIRSFMTSNFSLIYFSSLSHSFPFFLGAMFATITGI
                     NETTVRFQKNVRLWPRQYVLAAMVGAFTLLLVLMVTLDFNHITTYLFGFALASLFASI
                     MIYAARVLHEQTPDVQEPKAITYIADISYGIYLFHWPFYIIFSQLMSHILAVILTVFF
                     SILFATVSYYIVEPLVQGRKPNLLGLEIDCSPYYKWIVGGALALALLTLGTCMIAPKV
                     GKFEKQLLVSSLQQAQSNMERTHTLAAG"
BASE COUNT         9000 a         5232 c         6481 g         8678 t
ORIGIN      
        1 ctatccaaaa ggctggcggc attaatgcca aaatgtctgg taatgagatt atctcagcaa
       61 ttaacctcaa ctcctacgga gtaacaatcg caggtaaaca catcgctctc gatgggaata
      121 cgacggttaa tggcaccttt accacaaaaa tagccgaggc tatcaagatt agggctgatc
      181 agattattgc aggcacgatt gacgctgcta ggattagagt gattaacctt aacgcaagta
      241 gtatcgttgg tttagacgct aactttatca aagctaaaat tggctatgct atcactgatt
      301 tgctcgaggg taaggtcatt aaggctcgta atggagcgat gcttatcgac ttaaatacag
      361 ctaagatgga ctttaatagc gatgccacaa ttaattttaa tagcaaaaac aatgccttag
      421 tacgtaaaga tggcacacat actgcctttg tacattttag taatgcgacg cccaaaggtt
      481 atacagggtc agcgttgtat gcatcgatcg ggataacctc atctggtgac ggtgttaact
      541 cggcttcttc cggtcgtttt gcagggctaa ggtcatttag gtacgctacg ggatataatc
      601 acactgcggc agtcgaccag actgaaattt acggtgataa tgttttagtt gtggatgatt
      661 ttaatattac tcggggattt aagtttagac cagacaagat gcaaaaaatg cttgacatga
      721 acgacttgta tgcggctgta gtagccttag gccgctgttg ggggcacttg gctaacgtcg
      781 gctggaatac tgctcatagc aattttacaa gtgctgtgaa tggggaattg aataactaca
      841 tcacaaaaat ttaacaggag ataatatgca attaactatt aaaaacaaag atttaaacac
      901 actatattgt gtactagaca aaatcaaagt cacgaacatg cgagcaaacc gcggacgtgc
      961 taagctactc gcaaaagtag tagataaatt caaagagtac gccaaggatg agggtgacct
     1021 tattgatctg tatgctcaaa aagacaaaga tggcaagttt gtcattgatg agcacaaaaa
     1081 catcaagcta gcagaccccg ctaaactcga cgagttcaac ggcctactca acgagctagc
     1141 tgatgaagaa attgtgatta aagggggtga gtactccaag cgatttattg actttttaaa
     1201 ctttttagaa gagtgtgaag atgaatttac atcatctgaa atcattctta tcgacaacat
     1261 tttggaacaa tttgaagaaa gtaaaaaagg agaaaaacca tgagaaattg gaaagtgaca
     1321 ggaaaatacc cacaatttga cagcacagta gcagtcgcaa gcacacatat tattatcact
     1381 gctgaggatg gctcagtcat ctctcaactt gttaagcaag acttaatctc gactaatgac
     1441 acagagatta tcaaagctac tttggaagaa tttaaaaaat ctgaatacgt tgaaattgca
     1501 atgggcgaag ccgtgcaaaa ggtagacgac cttgaaaaaa tctcacagga aactgctaag
     1561 actgccaaga ctgctcaaac agccgcagga ttagctaagg tgtccgcaga gcgtacacag
     1621 cgaatgatta acttgcaaac catccacatg ttaacgagcg gcggcaagat tgattctgac
     1681 atttataaag gcatgcttga gctaatcgag ccagccaaaa aaggtgagta tcaagcctat
     1741 gatgtcttta cggtggtcga cagtactaaa gaggaagacg gtgaagcagg cgaaggcaat
     1801 cttgtctttg tacatgtcaa cgagccgttt acttatgagg cacagacctt agaggagcta
     1861 gagtcagaag ccaaagtaac agttatcaag tacgctgatt tggttaaaca agattagagg
     1921 tgttttatgg caacagagtt gatatttggc gtcggtggct ttattttagc tatcgtcacg
     1981 acttacaata tttttaatgc aaaatctatc aagcatgcga cagatattac attgttgcag
     2041 tctgaggttg agcatttaaa aattgtcact cgtcaaaatg ctaggcgtct tgaggagcat
     2101 gatgagcaaa acaaaacgct catcacaatg acagagcaaa ttaaaaacct caatcgtgag
     2161 gtaagagaac ttaaagatat tatgaaaggc gaagcatgat caatttaaaa ttacgactac
     2221 aaaacaaagt aaccttgatg gctattttag gagctatctt tttactggca cagcaattag
     2281 gtattaaact accatcaaac atcgcggata ttgcaaacac agctgtaacg cttttggtat
     2341 tgctcggtgt tgtcacagat ccaaccacga aaggcctgtc agacagtgag caagcattga
     2401 cttaccacga accaaaacaa taggagggga catgcgagca gtcacacaaa tagcactagt
     2461 aatagcaatc gcaatactgt atgtgccatt atctgttgtt gctctgatct tttatccatt
     2521 tttagataag gaggacagat gaccttttta gataaaatta aacaaggctg tttagatggc
     2581 tggactaagt ataaaatctt gccatccttg acagctgctc aggctatttt agagagcggt
     2641 tggggcaaac atgcaccaca taacgcttta tttggtatta aggctgatgc gagctggaca
     2701 ggtaagtctt ttgacactaa aactcaggag gagtaccagc ctggtatcgt cacggatatt
     2761 gtggaccgat ttagggccta tgatagttgg actgacagta ttattgatca tggcaaattt
     2821 ttaaacgata atccacgcta caaagcagtt atcggtgaga ctgactataa aaaagcttgt
     2881 tacgctatta aagcagctgg atacgctacg gcaagtagct atgtcgaact tttaatccaa
     2941 ctgattgagg aaaacgactt acaaagttgg gatagagaag ctcttaaaaa taataaggag
     3001 gaaacgatga caaccgcaaa cgaaattgta caatactgtg ttaaccttgc taattcaggc
     3061 atgggtgttg acaaagacgg tgctcacggg acgcaatgct gtgacttgcc ttgttttgtc
     3121 gctaaaaatt ggtttggtgt tgatctttgg ggcaatgcga ttgatttatt agacagcgca
     3181 agtgcgcaag gctgggaagt ccatcgtatg ccaacagagg caaacccaaa agcaggcgct
     3241 acatttgtcc aatcagtgcc gtatcatcaa tttggacata cgggaattgt cattgaggat
     3301 agcgacggct acactatgcg gactgttgaa caaaacattg atggcaatgc agacgcctta
     3361 tatgtcggcg caccagctcg ttttaatact cgtgacttta ctggcgttgt tggatggttt
     3421 tacccaccat atcaagggga tacagtcacg caaccagtca gcaccgagcc gcaaacttct
     3481 gacactatcg tagagacagc aaaaacaggc acctttaccc ttgatgttgc agagatcaat
     3541 atcagacgct ggccaagtct agccagcgag gttgtaggta tctacaagca aggtgatact
     3601 gtcagctttg atagcgaggg ctacgctaat ggctattatt ggattagcta tgttggaggc
     3661 ttaggtatgc gtgactacct agctattgga cagactgata aagacgggaa ccgcatcagt
     3721 atttggggta aattaaatta gtgtaaccga catcaatgtc ggtagcaaaa aattatggag
     3781 gtaaagctcc tttagataag acaaaaccgc tctcttaatc gagggcggtt tttgtgtctt
     3841 aaagattcta tatttgacga atgcaacata ttatgtaata atgtaaatga acataaacag
     3901 taaaagcatt atctctatgt tccgaccttt ccatgtcgtt aaactctcgc cattttggca
     3961 atgagggggc ggagggacgc gctcgttaac agaagtatcc cgttggcaat gcgtcctacc
     4021 aatacccagt tggtaggatt ttttattttt agaaggcaaa taatgaagag taaaaaatta
     4081 gtattcggtc agattgattt aaacatgtgt cgagatttcg atttggtaca agctttagac
     4141 tatgatttta aagagaagaa gctatataac aaaggccgag gttttgctat tgtgttggta
     4201 agtatccaaa atctaacttt tgcaatccct ttgagaagta atattcctaa aaaatatcaa
     4261 ctaaaatata aattaagaga ctctaaaaaa tacggatgcg tagaggggct tgatattggc
     4321 aaagctctag tagttgaaga tccaaaatat attttaaaca gaacgttcaa attacgagag
     4381 caggttgatt attttaagat tgttgataat gatatactta ttgttaacaa gttgataaag
     4441 gctatcatag attataatca agctgtagct aatagtgatc aacataaatt aacagatcct
     4501 aaacgtttca aattctctac atttccaaac tataccgaca gattaaaaag cattaccgat
     4561 gccgattatc ttcgttgaca ccctcgcaca atcatgaacc aattaccata gtaagaatta
     4621 gccgaaataa aaaaccaacc gctcagatta tttctgggcg gtttttttgt gtctaaaaat
     4681 tttttgaaat cttagttttc ttcttcggta gtagtatcgt tataaactat ttcttctgaa
     4741 tcatccacag aattttctat ttcgtctgtt gtagaatctt caatattatc aatttcactt
     4801 acagggcttt ctgttaagag tccgcccttt tcataattaa tattaaatcc atcagcggtg
     4861 ttgaaaacac gaacagtttc attaattact ccatcggaag ataaagcaga tactaaaact
     4921 gatcttgcta ataactcagt cccctgatat tcagggatgg cgctgtagaa tacataaaca
     4981 tcaggattct tagtgatatg gcttaaaact tttttctcaa tatattgcat cccaccttta
     5041 cgtgttccta cattttgcat ttgagttcca gtaatagcgt ttttccgtat ggactttcct
     5101 ccaaggctat cggcaaaaag atggctacgt acaaataagt gactgttgta ttgtttacct
     5161 tttaatgttg ttaacactac aggtacattg ttggtaactt tgtatgactt agtacgtctt
     5221 gaatcatatt ctttctcact aatttcttca ttatcggctc tattataaaa tctgaaccaa
     5281 ccgcttggtt cgggatttgt ttcccatttt tcacggtatc ctttagacat gtcaatcata
     5341 tcttttgtga caacgccgta agcgcctgtt gaacgtttat agccatctaa tgggttataa
     5401 actacatcag atacggttac tcttttttcg cttgtacctt gtcctttata gactctctcg
     5461 gttgttttat atatcttagg aaaagcagat tggtcaatgt ttgactcacc aattacagta
     5521 taatagtctt tatattcacc ataagtctga tttactgaga ctgttttagc taagactgta
     5581 ctgtgatgat aagttggaat cgccatcaca gcaaatgatg cgaatgctgc aacaactatt
     5641 ctggcgagag agtttctaag ctttttagac atatccatgt cctcctttaa ttatttacag
     5701 gttaagtata ccactttgaa ttaaaaaaac ttaaaattaa taaaattaat ttgttgccaa
     5761 tattgtacta aaatttcttt ttatttaata ttcgttaata agaagtggtt ttatttgtaa
     5821 taaagtagat gttattaaat tttaaataag ttttaaatct aactatatta tttcctgtaa
     5881 aatacgaata ataagataag gaggtgcatt atgctaacat acgatgagtt taagcaagct
     5941 attgatgacg gatatatcac aggcgacaca gtggcgatcg tgcgcaaaaa cggacagatt
     6001 tttgattatg cgttgccgaa tgaagaggta agaaatgggg aggttgtaac atacgaaaat
     6061 gtggaagaag tgctgaggga attagacaaa taaaaaagac ttttccaagt cccaaaatca
     6121 gatgctcccc agcgcaaaat tactacgtta tttactacgt tgttttcaaa atcagtgtaa
     6181 ttgactagat aatgtaaagt tgtaaagtgt tgatttataa agtgattgag taatgatagc
     6241 tattgagttt aagaggtctg ggatttatgc tataataaaa atactattaa tagattgtgt
     6301 aagaacacaa gatataatta aaggagtgga aatgaagaga attgcaatag atgctatggg
     6361 tggagataac gctcctaaag ctattgttga gggtgttaat caagtaatag aagcattttc
     6421 agatatcgaa attcaacttt acggtgatca gacaaagatt aactcctatc ttattcaatc
     6481 agatcgtgtt gctattattc atacagatga aaaaattatg tcagatgatg aacctgcaaa
     6541 agctgttcgc cgtaaaaaga aggcttcaat ggttttagca gctaaggcag tgaaagaagg
     6601 aaaagcagat gccattattt cagcagggaa tacaggtgct cttttagctg taggtttgtt
     6661 tgttgtgggg cgtatcaagg gagttgatcg tccaggatta ttatcaacta ttcccacagt
     6721 aaccggatta ggatttgata tgttggatct tggagctaat gctgaaaata cggtaaaaca
     6781 tttacatcaa tatgctattt taggctcttt ctatgctaag aatgtacgtg ggattgctaa
     6841 tccacgtgtt ggtctattaa acaatggtac agaagaaaca aaaggagatc cccttcgtaa
     6901 ggccacttat gaacttttaa cagcagataa tacaatatct tttgttggta atgtcgaggc
     6961 gcgagaactt atgtcaggtg ttgcagatgt tattgtatca gatggtttca cgggaaacgc
     7021 agtgttgaaa tcaatagaag gaacaggtat tagcattatg gggcaactga aacagataat
     7081 taatagcggc ggtattaaga ctaaaattgg agctagtcta cttaaaagta gtctttacga
     7141 gatgaagaag actcttgact actctagtgc tggaggtgca gttttatttg gtttaaaggc
     7201 acctgttgta aagtctcatg gttctagtga tgtaaaagct attttttcaa cgataaaaca
     7261 agtacgtacg atgctagaca ctaacgtggt cggacaatta gtagaagaat ttgctaagga
     7321 gactcaagta aatgactaga caggagattt ttgaaaggct gattaactta attcagaagc
     7381 aaagaagcta tttgagtgta gctattacag aacaaacaca tttaaaaaat gatttagcgg
     7441 ttgactctat tgaactagtt gaatttatta ttaatgttga agatgaattt catattgcta
     7501 ttcctgatga agatgttgag gatatggtat ttatggaaga cgttttagat tatttagttc
     7561 agcgtttgac ttagttagaa taataaaaag agcgtaagct ctttttatta ttctttaaaa
     7621 acgaaccttt tttcaaaaaa aacttataaa cgtaagtaat atcttgaata tttttataga
     7681 gtatgttact cttaaatgaa aacagaaaga aaggcgaata atcaagtgac taaccagctt
     7741 atttataaag gaaaagcgaa agatatttat agtacaaaag atgaaaatgt aattagaacg
     7801 gtctataaag accaagctac tatgttgaat ggagctcgta aggaggctat tgatggcaag
     7861 ggagcactaa ataatcagat ttcatctctt atttttgaga aattaaataa ggctggtgtg
     7921 gtgacacatt atattgagca aatttcaaaa aacgaacaat tgaataaaaa agttgatatt
     7981 attccacttg aggtggtgtt acggaatgtg acagcaggct cattttcaaa acgttttgga
     8041 gtggaagaag gacgtgttct tgaaacgcca attgtggaat tttactacaa aaatgatgat
     8101 ctgaatgatc cttttatcaa tgatgagcat gtgaagtttt tgggtattgt taatgatgag
     8161 gagattgctt atctgaaagg agagactcgc cgtattaatg aactcttgaa aggttggttt
     8221 gctcagattg ggcttaactt gattgacttc aagttggagt tcggatttga tcaagaaggt
     8281 acaattatct tagcagatga actttcgcct gataactgtc gcctatggga taagaatggt
     8341 aaccatatgg acaaggatgt ttttagaaga gaccttggca atctgacgga tgtctatcaa
     8401 gttgtacttg agaagttaat agcattgtaa ctagaagagg aaggaattga atccgttcgg
     8461 gaaactccga aaaaaagatg gaacttactg aaatctcaat ttcagatgtc ctcctatttt
     8521 ccagtcgctc ccttgtcgga tttggtatct tatatgaata aacgtatttt tgttgagaaa
     8581 aaggctgact ttggcattaa atcggctagc cttgtgaaag agttgacaca taatctacaa
     8641 ctgacttctt tgaaggactt gcgtattgtg caggtctatg atgtcttcaa tttggctgag
     8701 gatttactgg cgcgtgctga gaagcatatt ttctctgagc aggtgacaga ccgtcttttg
     8761 acggaagctg aaatcactgc ggagcttgat aaggttgcct tctttgccat tgaggcgctt
     8821 cctggtcaat ttgaccaacg tgctgctagt tcgcaagaag ctttgctatt atttggaagt
     8881 gacagtcagg ttaaggtcaa tacagctgag ctatacttga tcaataagga tattgcagaa
     8941 gcagagcttg aagccgttaa gaactatctt ttgaaccctg ttgattcgcg tttcaaggac
     9001 attactttgc cgcttgaaga gcaggctttc tctgtatctg ataagacgat ccctaatctt
     9061 gatttctttg aaaattataa agctgacgat tttgcggcct ataaggcaga gcagggcttg
     9121 gctatggagg tcgatgacct tctcttcatc caagattatt tcaaatcaat cggacgtgtg
     9181 ccaactgaga ctgagttgaa agttttggat acttactggt cagaccactg ccgtcacaca
     9241 acctttgaaa ctgaattgaa gaacattgat ttttcagctt ctaaattcca aaaacaattg
     9301 cagacaactt atgataaata tatcgccatg cgtgatgagc ttggtcgttc tgaaaagcca
     9361 caaacactta tggatatggc gactattttt ggtcgttatg agcgtgccaa cggtcgtctg
     9421 gacgatatgg aagtctcaga tgaaatcaat gcctgctcag ttgagattga agtagatgtt
     9481 gatggtgtga aagagccttg gctcctcatg tttaagaatg agactcacaa tcacccaaca
     9541 gaaattgagc cattcggtgg agcggcgact tgtatcggtg gtgctattcg tgacccattg
     9601 tcagggcgtt catacgttta tcaggctatg cgtatttcag gcgcaggcga tatcacgact
     9661 ccgattgcgg aaacacgtac tggtaaattg ccacaacagg ttatttctaa gactgcggcg
     9721 cacggctatt cttcatatgg taaccaaatt ggacttgcga caacttatgt gcgtgagtac
     9781 ttccaccctg gcttcgtagc caaacgcatg gagcttggag ctgtggtcgg agcggcacct
     9841 aaggaaaatg tggttcgtga aaaaccagaa gcaggtgatg tggtaatctt gcttggtggt
     9901 aaaacagggc gtgacggtgt cggcggtgcg acaggttcat ctaaggttca aacggttgag
     9961 tctgtggaaa cagctggcgc agaggtacaa aaagggaatg ccatcgaaga gcgtaagatt
    10021 caacgtctct tccgtgatgg tgaagtgact cgtctcatca aaaaatcaaa cgactttggt
    10081 gctggtggtg tctgtgttgc tatcggtgaa ttggctgacg gtcttgaaat cgatttggac
    10141 aaggtcccac ttaaatacca aggtcttaat ggtactgaaa ttgcaatctc agaatctcaa
    10201 gagcgtatgt cagtcgttgt tcgtccaagt gatgtggatg ccttcatcgc agcttgcaac
    10261 aaggaaaata tcgatgccgt tgtagttgcg acagttaccg agaaaccaaa tcttgtcatg
    10321 acttggaatg gtgaaaccat cgttgacttg gaacgccgtt tccttgatac caacggtgtc
    10381 cgtgtcgttg ttgatgttaa attcgttgac aaggacttga cagttccaga agcacgcaca
    10441 acatcagcag agacacttga agcagatacg cttaaggtct tgtctgatct caaccatgct
    10501 agtcaaaaag gtcttcaaac tatctttgac tcatctgttg gtcgctcaac cgttaaccac
    10561 ccaatcggtg gtcgttacca aatcacaccg acagaaagtt ctgttcaaaa attgccagtt
    10621 caacatggtg tgacaagaac agcatctgtt atggctcaag gttacaatcc ttatattgct
    10681 gagtggtcac cttaccacgg tgctgcctat gctgtcattg aagcgacagc tcgcttggta
    10741 gcaacgggtg ctgactggtc tcgtgcacgt ttctcttacc aagagtactt tgagcgtatg
    10801 gataaacagg cagagcgttt tggtcagcca gtatcagctc ttcttggttc tattgaggct
    10861 cagattcaac ttggtttgcc atcaatcggc ggtaaggact ctatgtctgg tactttcgaa
    10921 gacttgacag taccaccaac cttggtagct ttcggcgtga caacagcgga catccgcaag
    10981 gttctctctc ctgagtttaa agcggctggc gaaaacattt actatatccc aggtcaagct
    11041 atttcagaag atattgattt tgaccttatc aaggctaact ttagccagtt tgaagctatt
    11101 caagctcaac ataagattac agctgcctca gccgctaaat acggtagtgt cctagaaagt
    11161 cttgctctca tgacttttgg taaccgtatc ggtgcttctg ttgaaattgc agagcttgac
    11221 agcagcttga cagctcaact cggaggtttt gtctttacat cagctgagga aattgctgac
    11281 gcggtgaaaa tcggtcaaac tcaggcagac tttacagtca ctgtcaatgg aaatgacctt
    11341 gctggcgcta gccttctagc agccttcgaa ggcaaattgg aagaggttta cccaacagaa
    11401 ttcgaacagg cagacgctct tgaagaagtt cctgctgtgg tatcagatac tgttatcaag
    11461 gctaaggaaa caattgaaaa accagtggtt tacattcctg tcttccctgg taccaactca
    11521 gaatatgatt cagctaaggc ctttgaacag gttggagcta gtgtcaactt ggtaccattt
    11581 gtaaccttga atgaggttgc tattgctgag tcagttgaca ctatggttgc taatattgct
    11641 aaggcaaata tcatcttctt tgctggaggc ttctcagcag cggatgaacc agatgggtct
    11701 gctaagttta tcgtcaatat cttgcttaac gagaaggtcc gcgcagctat tgacagcttc
    11761 atcgaaaaag gtagccttat catcggtatc tgtaatggtt tccaagccct tgttaaatca
    11821 ggtcttcttc catacggaaa cttcgaagaa gctggtgaga caagtccaac tctcttctat
    11881 aacgatgcca accaacacgt tgccaagatg gttgagactc gtatcgcaaa taccaactca
    11941 ccttggttgg caggagttga ggtcggcgat attcatgcca tcccagtttc acacggtgaa
    12001 ggtaaatttg ttgtcagcgc ttctgaattt gcagagctaa gagacaatgg tcaaatctgg
    12061 agccaatatg tggactttga cggacaacca tctatggatt ctaaatacaa tccaaacggc
    12121 tctgtcaatg ccatcgaagg gattaccagc aagaatggtc aaatcatcgg taagatggga
    12181 cactcagaac gctgggaaga cggactcttc caaaatattc ctggtaacaa agaccaaacc
    12241 ttgtttgcta gtgcagtaaa atattttaca ggaaaataat tttttcaaat tttttcataa
    12301 aacagataag gaaacaagag cgaagcgagc ttaactgtat ctttctgtcg tagtggtatt
    12361 tgggagccgt tgaggctaag actcaatgat tagcttgaaa atagcttgat agattttcta
    12421 ttttgatgtt ggcattggtg acgatagatc caaaattgag aaaatcatca aagctactta
    12481 agaagagata caaaaagaat taggaaaaaa gaatgacata cgaagtaaaa tctctaaatg
    12541 aagaatgtgg agtctttggt atctgggggc atcctcaggc agctcaagtc acttactttg
    12601 ggcttcatag ccttcaacat cgcggtcaag aaggagctgg tattgtttca aatgacaatg
    12661 ggaaactcta tggttatcga aatgttgggc tcctttctga agtttttaag aatcaatctg
    12721 aattagataa tttaactggg aatgcggcta ttggacatgt tcggtatgct actgcaggtt
    12781 ctgcagatat tcgcaatatt cagccttttc tttataaatt tcatgacggg caatttgctt
    12841 tatgccataa tggtaatttg acaaatgcta tttccttaag gaaagaatta gaaaagcaag
    12901 gtgcaatttt caatgcctcc tcagatactg aaattttgat gcacttgatt cgtcgaagcc
    12961 ataactcaag tttcatggga aaggtaaaag aagctctaaa tacagtaaag ggtggctttg
    13021 cctatctact gatgacagaa aataaactca ttgctgctct tgaccctaat gcctttcgtc
    13081 ctttgtcaat tggacaaatg caaaatggtg cctgggttat ttccagtgag acctgtgctt
    13141 ttgaggtggt aggcgcaaaa tgggttagag atgttgaacc tggcgaagtt attcttatag
    13201 acgatcgtgg tattcaatgt gatcgttata ctgatgaaac gcaactggca atttgttcga
    13261 tggaatatgt ctattttgca aggccggatt caactataca tggtgttaat gttcatacgg
    13321 ctcgaaaaaa tatgggaaag cgtcttgcac aagaatttaa acaggatgct gatattgtaa
    13381 ttggtgtccc aaattcgtcc ttatcggctg ctatgggctt tgctgaagaa tccggattac
    13441 caaatgagat gggtcttgta aaaaatcagt atacgcagcg aacctttatt caaccgacac
    13501 aagaattaag ggaacaaggt gttcgaatga aactatcagc ggtatctggt gttgtcaaag
    13561 gaaagcgcgt tgttatgatt gatgactcaa ttgtaagagg aacgacttct agaaggattg
    13621 tcggattatt aagagaagca ggagctagtg aagtacatgt tgctatagct agtccagaat
    13681 taaagtatcc ttgtttttat ggtattgata ttcaaacaag acgagaatta atttcagcaa
    13741 atcacgctgt tgacgaagtg tgtgatatta ttggcgcaga tagtctgacc tatctctcat
    13801 tagatgggtt gattgaatca attggactcg aaacaaaagc accaaatggt ggtttatgcg
    13861 tagcttactt tgatgggcat tatccaacac cgctttatga ttatgaagaa gaatacctca
    13921 gaagtttaga agagaaaaca agtttttata ttcaaaaagt gaaataagct ctgctaatta
    13981 tataaggaga aaacatgtct gaaaaaaatg cttatgcaaa atctggtgtt gatgttgaag
    14041 ctggttatga agtggttgaa agaataaaaa aacacgttgc tcgtacagaa cgtgcgggag
    14101 tcatgggagt tctaggtggc tttggtggga tgtttgactt gagtaaaaca ggagttaaag
    14161 agcctgtctt ggtttcaggg actgacggtg tcggaacaaa actgatgctt gctatcaagt
    14221 acgacaagca cgacacaatc ggtcaagact gtgttgccat gtgtgtcaac gatattattg
    14281 cagcaggtgc tgagccatta tattttttag attatattgc gacaggaaaa aataatccag
    14341 tcaaacttga agaagttgtt tctggcgttg cagaaggttg tgttcaagca ggagtagcac
    14401 tcattggagg tgagaccgct gaaatgcctg ggatgtatgg cgaagatgat tatgaccttg
    14461 ctggctttgc tgttggtgtg gctgaaaaat ctcaaatcat cgacggttca aaagtaaaag
    14521 aaggtgatat tcttttggga cttgcttcaa gtggtatcca ttcaaacggt tattctttgg
    14581 tacgtcgtgt ctttgctgac tatactggta aagagctgct tccagagctt gaaggcaaac
    14641 gacttaagga tgtcctcctt gagccaactc gtatctatgt taaagcagct ctgccattaa
    14701 tcaaggaaga actagtcaac ggtatcggcc acatcacggg tggtggcttt atcgagaatg
    14761 ttcctcgtat gtttgcggat gatttggctg cagaaatcga tgaggataag gtgccagtac
    14821 ttccgatttt caaggcgctt gaaaaatatg gtgacatcaa gcacgaagaa atgtttgaaa
    14881 tcttcaatat gggtgtcggt cttatgctag ctgttagtcc tgaaaatgtt aaccgcgtca
    14941 aagatctctt ggatgaacca gtttatgaaa tcggtcgtat catcaagaaa gcagacgata
    15001 gtgtggtgat taaataagtc actaaatttt ataagaaagg agtgtttagt tagtttgcct
    15061 aactgaacac gggattaaat ttctaggaaa aaagataaaa tgacttagac gcaagcgtcg
    15121 ttgttcgttt tcctattttt ctacgaaatt tttcggcaag ccgaatcatc cctttgtatc
    15181 gaatatgaaa atcgctgttt ttgcttctgg taatggttcc aactttcagg tcatagcaga
    15241 gcagtttcca gttagttttg tcttttcaga tcatcgtgat gcctatgttt tagagcgtgc
    15301 tcagaattta gccattccaa gcttcgcttt tgaactcaag gagtttgaga ataaggcggc
    15361 ttacgagcaa gccatcgttg atttgttgga caaacacgag attgacttag tatgtctggc
    15421 aggctatatg aagattgttg gagaaacctt actcttggcc tatgaggggc gtatcatcaa
    15481 tattcaccca gcctacctgc ctgaatttcc aggtgcccac ggtatcgagg atgcttggga
    15541 agctggtgtt gaccagtctg gcgtgaccat ccactgggtt gactctggtg tggataccgg
    15601 tcaggtcatc caacaagtgc gcgtgccacg cctagcagac gatagcctag aaagctttga
    15661 aacccgtatc catgaaaccg aatatcaact ctacccagct gtcttagata gcttgggagt
    15721 ggagaggaaa gtaatctagc ctttatctta aaattttagg taaagttagg aaagatagta
    15781 aagaagaatt aacgttccaa aaagaaagga attgaacccg tctggaaggc acagaaaaaa
    15841 gataaacatc tcctaggcgc aagcgtcttc gtcgagtttc ctatttttcc ttggccttct
    15901 agtcggactt ggtatcttaa atatgactaa acgtgcttta atctcagttt ctgataagtc
    15961 aggaattatt gactttgcaa aagaattgaa aaacttgggt tgggatatta tctcaactgg
    16021 tgggactaag gttgcccttg ataatgctgg agttgagact attgccatcg acgatgtgac
    16081 tggattccca gaaatgatgg acggtcgtgt taagaccctc catccaaaca ttcacggtgg
    16141 gcttttggcc cgtcgcgatg ttgacagcca ccttcaggct gctaaggata acaatatcga
    16201 gctgattgac ctcgtggttg tcaacctcta tcccttcaag gagactatcc ttcgtccaga
    16261 cgtgacctat gatttggcgg tggaaaatat cgatatcggc ggtccatcaa tgcttcgctc
    16321 agccgcaaaa aaccatgcta gcgtgaccgt tgtggttgac ccagcggact atgcgactgt
    16381 tttgggagaa ttagctgacg ctggtcagac gacatttgaa acgcgtcaac gcttggcagc
    16441 taaggtcttt cgtcacatag cagcctacga cgctttgatt gctgagtact tcacagctca
    16501 agtgggagag gctaagcctg aaaaattaac catcacttac gaccttaaac aggctatgcg
    16561 ttatggagaa aatccacaac aagacgctga tttctatcaa aaagccttgc caacagacta
    16621 ctcaattgct tctgctaaac agctcaacgg aaaagaattg tccttcaata atatccgtga
    16681 tgttgatgca gcaatccgta ttatccgtga tttcaaagac cgtccgacag tggttgccct
    16741 caaacacatg aacccatgtg gtatcggaca ggctgatgac attgagactg cttgggatta
    16801 cgcttatgaa gctgacccag tttcaatctt tggtggaatt gtcgtcctta accgtgaagt
    16861 tgacgcagcg acagccaaga agatgcaccc tatcttcttg gaaatcatca tcgcaccatc
    16921 atactcagaa gaagcgctag ctattctcac aaataaaaag aaaaacttgc gcatccttga
    16981 gttgccgttt gatgcccaag ctgccagcga agtggaagct gagtacactg gcgtagttgg
    17041 tggacttttg gtgcaaaacc aagacgttgt agctgaaaat ccatctgact ggcaagtggt
    17101 gacagaccgc caaccaacag aacaagaggc gactgccctt gagtttgcct ggaaggctat
    17161 caagtacgtt aagtctaacg ggattattat tactaacgat cacatgacgc ttggactcgg
    17221 tgcaggtcaa accaaccgtg tcggctcagt caagattgct atcgagcagg ctaaagacca
    17281 ccttgacggt gccgttctag catcagatgc cttcttccca tttgcggaca acattgaaga
    17341 agtcgctgcc gcaggggtca aagcaatcat ccagccaggc ggctcagttc gtgaccaaga
    17401 ctctattgac gccgcaaaca aacatggctt gaccatgatc ttcacaggtg tgagacattt
    17461 taggcattaa taaaaaaatg tggtctaatt aaaaccacat ttttttatta aaagaaaata
    17521 taagttaact ataatttgtt agctttatca gcatttaccc atgttccacg agatccgatt
    17581 tgaacataaa taccattact tggttgatca atttttaata ctttataact accagtgacg
    17641 gtaaaatatt cacctacacg gagaatttga tctcctaaaa cttttccttg gttatctgtt
    17701 tcatctaatg gtgtgggatc aatccagttt agtggagttg ggtctcctcc ggctaattct
    17761 ttattaacga tcaaattatt aacaagctga tctacacgaa aaacgccagg gaaggtaaca
    17821 gtatcaccga cctcaatgga aggttttgta ttgtcatttt gaaccacaga ctgtgcgggc
    17881 tctttaatgg gaatatagcg tcggtttcca gaaaaactga ggtagctaag ccatgtataa
    17941 cctccagcag ccacgacttt atcgtaataa acagattgac ctgcttcata gtaagcaaga
    18001 tcagggctat cgatactggt ttgtcctttg actggtaatc tggttgtaaa gtgataagtt
    18061 ccagaggggt caaatgaagc ttgagaaatg tgttttagtt gtcttgggta ggaatgactt
    18121 gtctgagatg ataagtcttt aaaatggata taaccactta cctgagattt tggaatttga
    18181 cgcttatggt atctttcagg gccttgtcca gcgttgtaat tatactcttc gatagtgaca
    18241 gtgtctccac ggatatcagc tacccatgct acatgaccgt aagcagcatt tgactgataa
    18301 gcgtttttat caaaccaagc gatagcccct atgcttggtg tcttattcac aggataaccc
    18361 tgatttttcg cgatatgtcc ccacgtgcag gcattaccgt agcctttagg taactgaaaa
    18421 ccattagcag agcttaaacg aaaagctgca aaagaagtgc attggcggat atacatgttc
    18481 cacgaatcga ttccattgcc ttttttccac ttactcggat agttatcgcc taaaacagct
    18541 gcatgaacaa gattttcctg ttgcgaaata agtgtagatg gcatagtagg tactagacca
    18601 ttaaaaccta aaaggattac tcctgagacc aaaaaacgat gaaatttttt cattaattac
    18661 ctcctgtaac ttattattcg aaagcaagaa acaaaaaatg ttatttttag atgattattt
    18721 tgaaaattgg ctttacttga tattaaataa ctatttgatt ggctaataga gtgttcctta
    18781 tttcaagaat tgtggtctac tatcacattt ttacaatgtt tcaattattg ataattaata
    18841 cattgtatca aaaggcgaac gtttatgata taatatctaa ttataatacg aaagaggtgg
    18901 gtgttttgaa attacttgtt gttggttcag gtggtcgtga acatgcgatt gctaagaagt
    18961 tgttagcgtc taagggtgtg gatcaggttt ttgtggcacc tggtaatgat ggtatgacct
    19021 tggatggtct ggacttggtg aatatagtag tttccgaaca ttccaggttg attgcctttg
    19081 cgaaggagaa tgagatttct tgggccttta ttggtcctga tgatgcgcta gcagctggta
    19141 tcgttgatga tttcaacagt gctggactca gagcttttgg tccaacaaag gcagcagcgg
    19201 agctagagtg gtcaaaagac tttgccaagg aaatcatggt caaatacaat gtcccaacag
    19261 cagcctatgg cacattttca gactttgaaa aagccaaagc ctacatcgaa gagcagggcg
    19321 cacctatcgt ggtcaaggct gatggcttgg cgctaggtaa gggtgtggtc gtggctgaaa
    19381 ccgttgagca ggcggtagag gcggcgcaag agatgcttct ggacaataag tttggcgact
    19441 caggagcgcg tgtggttatc gaggaattct tggatggcga ggagttttcc ctctttgcct
    19501 ttgttaatgg tgataagttc tacatcatgc cgacagctca ggatcacaag cgtgcctttg
    19561 acggagacaa ggggccaaac actggtggta tgggtgccta tgcgccagtt cctcatctac
    19621 ctcagagcgt ggtagacaca gcggttgaga cgatcgttag gcctgtcctt gagggcatgg
    19681 ttgccgaagg gcgtccttat ctaggtgtcc tttatgtggg gcttatcctg acagctgatg
    19741 gacctaaggt tatcgagttc aactcacgtt tcggtgaccc tgaaactcag attatcctcc
    19801 ctcgtctgac ttccgatttc gctcagaata ttgacgatat catgatgggc attgagcctt
    19861 acatcacttg gcagaatgac ggtgtgactt tgggtgttgt cgttgcctca gaaggctatc
    19921 cactcgatta tgagaaaggt gtgccactgc ctgaaaagac cgacggcgat atcatcacct
    19981 actatgccgg agctaagttt gcggaaaata gcgagctact tctctcaaac ggaggacgtg
    20041 tctatatgct tgtcaccaca gaagacagcg tcaaagcagg gcaggacaaa atctataccc
    20101 aactggccca acaagacaca acaggtctct tctaccgaaa tgacatcgga aacaaagcta
    20161 ttaaagaata aaactactca ttcaaatatt agtgtcagca atcagcgacc gaaggtcgct
    20221 ccaaaaagaa agaagaaagg aactgaacac gggactaatt tcctaggaaa aaaataaaac
    20281 tacctggacg caagcgtcat cgttagtttt ctgcgtcgta ggcgtctgat gctaaagcac
    20341 ctagtcgccc tgacgtgggt tcgtcttcga aatcaaagat ttcggactta ccgcatattt
    20401 ttctacggaa agtttcgaca agtcgaaacg cccctttata tcttaattat gaaaactcca
    20461 attatttcta ttatcatggg ctccaaatct gactgggcaa ccatgcaaaa aacggctgaa
    20521 attctagaca actttggcat tgcttacgag aagaaagtcg tctctgctca ccgcacgccc
    20581 gacctcatgt tcaagcatgc tgaggaagca cgtggtcgtg gcatcaaaat catcatcgca
    20641 ggagcaggtg gggcagctca cttgcctggt atggtggcag ctaaaacaac gctgcctgtt
    20701 atcggtgtgc cagtcaaatc acgtgtcctt tcaggtttgg attcgctcta ttccattgtg
    20761 cagatgcctg gcggtgtgcc tgtggcaacc atggctatcg gagaagcggg agcgactaac
    20821 gctgccctaa cagccctccg tatcctttct atcgaggacc aaaatctggc tgatgcgcta
    20881 gctcatttcc atgaggaaca aggaaaaatc gcagaggagt caagcaatga actcatttaa
    20941 gactattggg attattggtg gtggtcagct agggcagatg atggccattg cggccatcta
    21001 tatgggccac aaggtcatca cgctggatcc tactaatgac tgccctgcct cccgcgttag
    21061 cgaggtaatt gtggcgcctt acgatgatgt tgaggctttg ggacaattgg ctgcgtgttg
    21121 cgatgtgttg acttatgagt ttgagaatgt taatgcggac ggtttggatg ccgttgtgtc
    21181 agcttgtcag ctaccgcagg ggaccgatct gctccgcatt tcccaaaacc gtatctttga
    21241 aaaagacttt ctggcaaata aggctggtgt gactgttgct ccctataagg tggtgacgtc
    21301 tagccttgac ctagaggggc ttgattttac caagacctat gtcctcaaga cagcgacagg
    21361 tggttatgac ggtcatgggc aaaaggttat ccgctcagca gaagatttgc cagaggcgca
    21421 gcaattagct aactcagctc agtgtgtctt ggaagagttt gtcaactttg accttgaaat
    21481 ctcagtcatc gtgtctggaa atggagagga tgtgacggtc tttcccgttc aggaaaatat
    21541 ccactgcaac aatatcctgt caaaaactat cgtgccagct cgtatctcag atcaactggc
    21601 tgataaggct aagaaaatgg cggtgcagat tgccaagaaa ctccagctgt caggaactct
    21661 ctgtgtggaa atgtttgcga ccgcagatga tatcattatc aatgaaattg ccccacgtcc
    21721 ccacaactca gggcactact caatcgaggc ttgcgacttt tcacagtttg acacccacat
    21781 tttgggcgta ctcgggcaac ctctcccacc aatcaaactc catgctccag ccgtcatgct
    21841 taatgtcctc ggacaacacg tccagcaggc aattgactat gttgcccaaa accctagcgc
    21901 ccacctccac atgtatggta aactagaagc gaaacataac cgcaaaatgg gacatgtgac
    21961 actatttgca gaagatgcag atgaggtgga ggagttttag aacaggagta gattggtaag
    22021 atggagttaa gggaatttaa agcgtggtta ttaaaaaacc attttgaaga agatgagtta
    22081 tacaaggaat ctataaagtg ttatcaagtg gaagcatata aggctgccta tattttttcg
    22141 tatttagcaa atcataagtt cattgctaaa ttagctattg actacagtgg tgtctcatca
    22201 aattttatgt ctaaatgtcc cgatgatgaa gttagaaagt cgagttggca aaaacgtgtg
    22261 aattccttaa aaaatgaaga tgagtgggag cagacggtta acgaaaaatt aattcaagca
    22321 tgggaagatg ataatgtatt caaattacct ttcaaaatta aagaaaaata ttctcttatg
    22381 agggtattgc gtaataatgc agcccatgcg aaagactgtc gaatttctga atcaacagtt
    22441 ttagaattat ggaatgaaat tgagtatata tatccttact ttgtaatcaa cggaacgatt
    22501 gatgcatgga tggaagattt agaaaaacta gttagatatt caaatagtag catagaatct
    22561 caaaaccaat tacagaataa atttggagat ttttctactg aaaataagac cttaattgtt
    22621 aaaaagatta tacaaaaata tttggtagat tctgaatggg atgaaacgta cccagatata
    22681 gtgatgaatt ttttattata tatttttcaa gaaagtaatt atattaatca aattggtaaa
    22741 gacttaacgg aaaaagagga attgtatctg tctattggaa cgggtattta tcatttccaa
    22801 gctgaagcta ttgatattta ttctcaattt gaagagtcgc tgagtgatta tacatttaga
    22861 tatttttgtg aagaattttc ggataatttt tggaagttta ttgattctat ggattccgaa
    22921 gttaataaag agaacttgac agctactagt ttagaaattt tgaagaaaaa ttctgctatt
    22981 ttagtaaatg cagaatttaa tgagagccga tttttatctg ataatagtct ttttttcaaa
    23041 tctgtgttag ataaaattaa gcatttatat tactatacta tgcatcatac gggtcaacgt
    23101 catcataata caaatacttt tgactattca aaatttaatt catatattcc ttatattaac
    23161 tatatatttt ataggatatc gtcaaatcct ggattaaaag aagatgaaaa agtaatagat
    23221 tttgttaaga ggtgtaataa tttaatttca agtgactata gtgcagaatc ttggtatagt
    23281 gagcgtcaaa tgcaggatgt aattaaaaaa attaatgaaa aatacactat attggaagat
    23341 agtggaaggg agtcggatta atcaaattaa atttggtaga gagtttagga aatctaactt
    23401 actcattcta aatgctaagg aaattaagtt aaaaaataga aaggaaatgg gcactagttt
    23461 cactaaactg aacccgagcg gaaagctcgg aatttagata aaccgcctag gacgcaagcg
    23521 tccattgttg gtttcctaaa attcagtcgc tttctggtcg cccttggtat cttaaaatga
    23581 tcgaacgtta ttcacgccct gagatggcgg caatttggac agaggaaaat aaataccgtg
    23641 cttggttgga ggttgagatt ttggctgacg aggcatgggc agagttgggt gagattccta
    23701 aggaggatgt ggctaagatt cgtgagaagg cggattttga cattgaccgc attcttgaga
    23761 ttgagcagga gacgcgtcac gatgtggtgg ctttcacgcg tgcggtttct gagacgcttg
    23821 gtgaggagcg caagtgggtg cactacggtt tgacctcgac tgacgtggtg gacactgcct
    23881 acggttacct ctacaagcaa gctaacgaca ttatccgtcg cgatcttgag aatttcacca
    23941 atatcgtggc agacaaggcg cgtgagcaca aaatgaccat catgatgggt cgtacccacg
    24001 gtgttcatgc cgagccaacg actttcggtc ttaagttggc gacttggtac agcgagatga
    24061 aacgtaatat tgagcgtttt gaacatgctg ccgcaggtgt ggaagctggt aagatttcag
    24121 gtgccgttgg taactttgcc aacatcccac cttttgtgga agaatatgtc tgtgacaaat
    24181 taggcattcg tccgcaagaa atttcaacac aagttcttcc acgtgacctc cacgcagaat
    24241 attttgcagt gcttgcaagt attgcaactt ctgtcgaacg tatggcgaca gagattcgag
    24301 gtctgcaaaa gtcagaacaa cgtgaagttg aagaattctt tgccaaaggt cagaaaggta
    24361 gctctgctat gcctcacaaa cgcaacccaa tcggttcaga gaacatgaca gggctagcgc
    24421 gcgtgattcg tggtcacatg gtgacagctt atgagaacgt gtcactttgg catgagcgtg
    24481 atatttcaca ctcatcagct gagcgtatca tcacacctga cacaactatc ttgattgact
    24541 acatgctcaa ccgctttggt aatatcgtta agaacttgac tgtcttcccg gaaaatatga
    24601 tgcgcaatat ggaatcaact tttggtttga tttatagtca acgtgttatg ctcaaattga
    24661 ttgaaaaagg aatgacacga gaagaagctt atgacttagt tcaacctaag acagcttatt
    24721 cctgggacaa tcaagtggat ttcaaaccac ttttagaaga agacaccaaa gttacctctt
    24781 gtcttacaca agaagaaatt gatgaactat ttaatccgat ttattacaca aaacgtgttg
    24841 atgatatttt taatcgttta gggatttaat ataaaaaaaa gaaggtgatt cccttctttt
    24901 ttatttaaaa aacgaatatt ttctttaaaa atattaaaaa ggttagtttt taattagacg
    24961 ctgtgatata ataaagaaaa cagttgttgg agagaaacca tgttagaaca ttttggtgga
    25021 aaagtaaaag tgttaagact tgaaaagagg attagtcgcg aggacttgtg tggggatgag
    25081 tctgaacttt ctgttcgtca attagcacgg atagaactag gtcaatccat accaagttta
    25141 agtaaggtta tttttattgc aaaagcctta aacgttagtg tcggttactt aactgatggt
    25201 gctgatttag aactacctaa gcgttacaaa gaattaaaat accttatctt aaggacacca
    25261 acttacatgg atgatggaaa attacaagta cgagaagagc agtttgatga aatttttgag
    25321 gattattatg ataaattacc agaggaagag aaaataatca ttgattgttt acaggcaact
    25381 ttagatactt tattgagtga gaatactaac tttggcattg acttacttca agaatatttt
    25441 aatcaaataa agactaaggt acgctttagg caaaatgatt taatacttct agaattatat
    25501 ttagcttatc ttgatattga gggaatggat ggacaatatt cagataagat tttttatgat
    25561 tctttattag ataatctatc agaacaattt gaacaatttg aattagatga attatttata
    25621 gttaataaga ttatcattga tatttcatca ctaagcttaa aaaataaccg acttgataat
    25681 ttagaaaaag cgattgaaat gagtcaaaaa attatggcga aaattcaaga ttggaataga
    25741 atgcctattt taaaactaat agaatggaaa tattttttaa tcaaacaaaa agatataata
    25801 aaagcagaac aatcatttat gaaggcatgt ttgttcgccc aaatgacagc tgatcagtat
    25861 ttggaaaaca agttaattca agagtgggaa aaagatgtta aaagttatta acaggacaaa
    25921 aatgtcattt ttaaatattt aatagtaaga tataattcct aatataaaag ataattatta
    25981 aggagttttt atccatgtta aaaaagtata agtactattt tatattcgca gctctactat
    26041 cttttaaagt agttcaagag cttagtgctg ttgactggtg gcgattataa taaaagtagg
    26101 ccactgctct cttttacttt atgttataat agtcctatgg ctagaatttt agacaataat
    26161 gtaatgggaa atgaggagtt ttcggatcgg actcttcgcc ctcaatatct acacgaatat
    26221 attggacaag ataaagttaa ggaacaattc gctattttta tagaagcagc taaaagacgt
    26281 gacgaatctt tagaccatgt tttattattt ggacctccag gactgggaaa aacaacaatg
    26341 gcatttgtga ttgccaatga attgggagtt aatttaaagc aaacttcagg tcctgccgtt
    26401 gagaaagctg gagatttggt agctatttta aatgaattag aaccagggga tattttgttt
    26461 attgatgaaa ttcaccgcat gccaatgtct gtcgaggaag tactatatag tgctatggaa
    26521 gacttctata ttgatattat gattggcgct ggggatacta gtcgtagtat tcatttggat
    26581 ctgcctccat ttacattgat tggtgctact acacgtgcag gcatgttatc taatcccctc
    26641 agagctcgtt ttggtatcac tggtcacatg gaatactatc aagaaaagga tttgacagag
    26701 attgtggagc gtacagctac tatttttgaa ataaaaatag accatgaagc tgcacggaaa
    26761 ttagcttgtc gcagtagagg aacgccccgc attgctaatc gattactaaa acgagtgcgt
    26821 gactatgctc aaattattgg tgatggcatc ataacggctc aaataactga tagagctttg
    26881 actatgttag atgttgaccg cgaaggtctc gattacattg atcagaaaat tttacgaacg
    26941 atgattgaga tgtatcaggg aggaccagtt ggtttgggga cattatctgt gaatattgcc
    27001 gaggagcgta atacagttga agagatgtat gaaccctact taattcaaaa aggctttctc
    27061 atgcgaacac gaacaggtcg tgtagcgacg caaaaggctt atcgtcatct tggctatccc
    27121 tatcaaaaca cttaatgatt tttcaaatct aagaaaatta atctgaacct gctttttgtg
    27181 ttcggatttt ttgataagtt gacagaaaat tattagattg atttctccga tatcagttag
    27241 aaatttgata taataattca aaggagtatt taatgaaaaa agtatgtttt gtctgtctgg
    27301 gtaatatttg tcgaagcccc atggctgagt ttgtaatgaa gtcaatagta tcaagtgatg
    27361 ttatgatgat agaaagtcgt gctacttctg attgggaaca tggaaaccct attcactcag
    27421 gtacacagtc catattaaaa acttaccaaa ttaattatga tataactaaa tgctccaagc
    27481 agataactat aactgatttt aacacctttg actatattat tggtatggat agcgataatg
    27541 tgaaaaatct caaagagatg tcgcaacatc aatgggactc taaaatctac ctgtttagag
    27601 aagggggtgt tcctgatcct tggtacacta acgattttga agaaacctac caattagtta
    27661 gaaaaggatg ccaggattgg ctttctcgtt taatgagtaa agagtattga tattagaagt
    27721 tgagtaaaag aaatgataga tatgcaagat atagtaaaaa aatggagtat tacacgggcg
    27781 aagttggaaa ttgtttcggt gattgtcata ttggtttgtg caatttctgt ttttagcgta
    27841 agaatttcga ataagacaag tttgacctat gataaagggc gtatgcacta tactggttac
    27901 gtgattaacc ataaaatgaa tggagaaggg aagcttgtct accccaacgg tgatatctat
    27961 gagggtactt ttaagaatgg cctatttgaa ggaaaaggaa cttttactgc taagacgggc
    28021 tggttatata acggggagtt tcataaagga caagcaaacg gcaaaggtgt gttaaaagca
    28081 aagaataata aagtctataa agggattttt aaacagggga tatttcaaaa atgagaataa
    28141 aatggttttc gtttgttagg gtaacaggac ttttactggt tttactctac cactttttta
    28201 aaaatgtatt tccaggaggt tttattggtg ttgatatttt cttcaccttt tcaggatatc
    28261 taatcacagc cctcttgatt gatgaataca caaaaaaaga gtctatcgat attatcggtt
    28321 ttttaaaaag acgcttttat cgaattgttc ctcctttggt gttaatgatt ttattgacca
    28381 ttccttttac gtttttaatt aagaaggatt tcattgctaa tataggaagt cagattacag
    28441 ctgttttagg atttaccact aatatttatg aaatattgac gggaagtagt tatgaaagcc
    28501 aatttattcc acatctcttt gttcatacgt ggagcttagc tattgaagtt catttttact
    28561 tgttgtgggg tgtatttgtt tggttattag ctagacgcaa ggagactcag aaacaactga
    28621 gaggactact gtttttgatt tctttgggaa tatttgctat tagtttcttg agcatgttta
    28681 taagatcttt tatgacctca aatttttccc tgatttattt ttcgagtctt tctcacagtt
    28741 ttcccttctt tttaggggcg atgtttgcca cgataacagg tattaacgag actactgttc
    28801 gatttcaaaa aaatgtacgt ttatggccgc gccagtatgt ccttgctgct atggttggag
    28861 catttacact tttgcttgtg ctaatggtca cattggattt taaccatatt acgacctatc
    28921 tatttggctt tgctttggct agcttattcg catcaattat gatttatgca gcgcgtgttc
    28981 ttcatgagca aacaccagat gtacaagagc ctaaagctat cacttatata gctgatatta
    29041 gctatgggat ttacctcttc cattggccat tttacattat ttttagccaa ttaatgtctc
    29101 atattttggc agttattcta acagttttct tttcaatctt gtttgccact gtgtcttact
    29161 atattgtgga acctttggtc caagggagaa aaccaaacct gcttggttta gaaattgact
    29221 gttctcctta ctataagtgg attgtaggag gggctctcgc cttagcatta ttaactttag
    29281 gaacttgtat gatagcgcct aaagttggta agtttgagaa acaattgttg gtcagttccc
    29341 tacaacaggc tcaaagtaat atggagcgga cacatacact agctgcagga g
//
LOCUS       DAXMQE010000021        27918 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.021, whole genome shotgun sequence.
ACCESSION   DAXMQE010000021 DAXMQE010000000
VERSION     DAXMQE010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 27918)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27918)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27918
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.021"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            <1..596
                     /gene="mvaD"
                     /locus_tag="ACF4ZO_001133"
     CDS             <1..596
                     /gene="mvaD"
                     /locus_tag="ACF4ZO_001133"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0004163 - diphosphomevalonate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HFD5486684.1"
                     /translation="CDQLFNTQLDQKALAQKAKFASGSSSRSFFGPVAAWDKDSGAIY
                     KVETDLKMAMIMLVLNAAKKPISSREGMKLCRDTSTTFDEWVEQSAIDYQHMLTYLKT
                     NNFEKVGQLTEANALAMHATTKTANPPFSYLTKESYQAMEAVKELRQEGFACYFTMDA
                     GPNVKVLCLEKDLAQLAERLGKNYRIIVSKTKDLPDV"
     gene            589..1602
                     /locus_tag="ACF4ZO_001134"
     CDS             589..1602
                     /locus_tag="ACF4ZO_001134"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004631 - phosphomevalonate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0016126 - sterol biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HFD5486685.1"
                     /translation="MSNYCVQTGGKLYLTGEYAILTPGQKALIHFIPLMMTAEISPAA
                     HIQLASDMFAHKAGMTPDASYALIQATVKTFADYLGQSIDQLEPFSLIITGKMERDGK
                     KFGIGSSGSVTLLTLKALSAYYQITLTPELLFKLAAYTLLKQGDNGSMGDIACIAYQT
                     LVAYTSFDREQVSNWLQTMPLKKLLVKDWGYHIQVIQPALPCDFLVGWTKIPAISRQM
                     IQQVTASITPAFLRTSYQLTQSAMVALQEGHKEELKKSLAGASHLLKELHPAIYHPKL
                     VTLVAACQKQDAVAKSSGSGGGDCGIALAFNQNARDTLISKWQEADIALLYQERWGEN
                     DQP"
     gene            1589..2578
                     /gene="fni"
                     /locus_tag="ACF4ZO_001135"
     CDS             1589..2578
                     /gene="fni"
                     /locus_tag="ACF4ZO_001135"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004452 - isopentenyl-diphosphate
                     delta-isomerase activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HFD5486686.1"
                     /translation="MTNRKDDHIKYALKYQSPYNAFDDIELIHHSLPSYDLSDIDLST
                     HFAGQDFDFPFYINAMTGGSQKGKAVNEKLAKVAAATGIVMVTGSYSAALKNPNDDSY
                     RLHEVADNLKLATNIGLDKPVALGQQTVQEMQPLFLQVHVNVMQELLMPEGERVFHTW
                     KKHLAEYASQIPVPVILKEVGFGMDVNSIKLAHDLGIQTFDISGRGGTSFAYIENQRG
                     GDRSYLNDWGQTTVQCLLNAQGLMDQVEILASGGVRHPLDMIKCFVLGARAVGLSRTV
                     LELVEKYPTERVIAIVNGWKEELKIIMCALDCKTIKELKGVDYLLYGRLQQVN"
     gene            complement(2808..4085)
                     /locus_tag="ACF4ZO_001136"
     CDS             complement(2808..4085)
                     /locus_tag="ACF4ZO_001136"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004420 - hydroxymethylglutaryl-CoA
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0015936 - coenzyme A metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HFD5486687.1"
                     /translation="MTKTNLNWSGFSKKTFEERLQLIEKFKLLNAENLNQLKTDILLP
                     IQTANQMTENVLGRLALPFSIAPDFLVNGSTYQMPFVTEEPSVVAAASFAAKLIKRSG
                     GFKAQTLNRQMIGQIVLYDIDQIDNAKAAILHKTKKLIALANKAYPSIVKRGGGARTI
                     HLEEKGEFLIFYLTVDTQEAMGANMVNTMMEALVPDLTRLSKGHCLMAILSNYATESL
                     VTTSCEIPVRLLDRDKTKSLQLAQKIELASRLAQVDPYRATTHNKGIFNGIDAVVIAT
                     GNDWRAIEAGAHAYASRNGSYQGLSQWHFDQDKQVLLGQMTLPMPIASKGGSIGLNPT
                     VSIAHDLLNQPDAKTLAQLIASVGLAQNFAALKALTSSGIQAGHMKLHAKSLALLAGA
                     TQDEITPLVNALLADKPINLEKAHFYLSQLRQS"
     gene            complement(4072..5247)
                     /locus_tag="ACF4ZO_001137"
     CDS             complement(4072..5247)
                     /locus_tag="ACF4ZO_001137"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004421 - hydroxymethylglutaryl-CoA
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HFD5486688.1"
                     /translation="MTIGIDKIGFATSQYVLKLEDLALARQVDPAKFSQGLLIESFSV
                     APITEDIITLAASAADQILTDEDRSKIDMVILATESSTDQSKASAIYVHHLVGIQPFA
                     RSFEVKQACYSATAALDYAKLHVASKPDSRVLVIASDIARYGVGSPGESTQGSGSIAL
                     LVTTNPRILALNEDNVAQTRDIMDFWRPNYSFTPYVDGIYSTKQYLNCLETTWQAYQK
                     RENLQLSDFAAVCFHIPFPKLALKGLNNIMDNTVPPEHREKLIEAFQASITYSKQIGN
                     IYTGSLYLGLLSLLENSKVLQSGDKIGFFSYGSGAVSEFYSGQLVAGYDKMLMTNRQT
                     LLDQRTRLSVSKYEDLFYEQVQLDDNGNANFDIYLTGKFALTAIKEHQRIYRTNDKN"
     gene            5456..6295
                     /locus_tag="ACF4ZO_001138"
     CDS             5456..6295
                     /locus_tag="ACF4ZO_001138"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HFD5486689.1"
                     /translation="MTKADQIFKANIQKIINEGSLSEQARPKYKDGRTAHSKYITGAF
                     AEYDLAKGEFPITTLRPIPIKSAIKELFWIYQDQSNSLDVLEAKYNVHYWNEWEVDQT
                     RTIGQRYGAVVKKHDIISKILKQLAENPWNRRNVISLWDYEAFEETKGLLPCAFQIMF
                     DVRRVGEDLYLDASLTQRSNDILVAHHINAMQYVALQMMIAKHFGWKIGKFFYFVNNL
                     HIYDNQFDQAQELLKRQPVASQPKLVLNVPDGTNFFDIKPDDFELQNYDPVKPQLHFD
                     LAI"
     gene            6375..6872
                     /locus_tag="ACF4ZO_001139"
     CDS             6375..6872
                     /locus_tag="ACF4ZO_001139"
                     /EC_number="1.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA];
                     GO_function: GO:0005542 - folic acid binding [Evidence
                     IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HFD5486690.1"
                     /translation="MTKEIIAIWAEDEAGLIGVAGKLPWYLPKELEHFKKTTLHQAIL
                     MGRVTFEGMNCKRLSQRQTLVMTRNRDYQVDEVLTMTSIEKVLEWYHAQDKTLYIIGG
                     NKVLEAFNGYFDRIIKTVIHHRFKGDTYRPNLDFSHFTQESQTFYARDAKNPYDFTVT
                     ALKHK"
     gene            6892..7062
                     /locus_tag="ACF4ZO_001140"
     CDS             6892..7062
                     /locus_tag="ACF4ZO_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486691.1"
                     /translation="MQRSIFGVFTAFLCVICVLCAIPAFKKNRYGLGSLFLLNAFTNL
                     VNSIHAFYGTLF"
     gene            7192..8421
                     /gene="clpX"
                     /locus_tag="ACF4ZO_001141"
     CDS             7192..8421
                     /gene="clpX"
                     /locus_tag="ACF4ZO_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HFD5486692.1"
                     /translation="MAGSRTNDIKVYCSFCGKSQDDVKKIIAGNNVFICNECVALSQE
                     IIKEELAEKVLADLTEVPKPKELLDVLNQYVVGQDRAKRALSVAVYNHYKRVSFTESR
                     DDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTV
                     ASVPPQGGRKHPNQEMIQIDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNSRKID
                     DNASYMQEIISEDIQKFGLIPEFIGRLPVVAALEQLNTSDLIRILTEPRNALVKQYQA
                     LLSYDGVELEFDKAALEAIATKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVR
                     ITKAAVEGKSKPVLETA"
     gene            8431..9030
                     /gene="yihA"
                     /locus_tag="ACF4ZO_001142"
     CDS             8431..9030
                     /gene="yihA"
                     /locus_tag="ACF4ZO_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTP-binding protein
                     YihA/YsxC"
                     /protein_id="HFD5486693.1"
                     /translation="MAEEQVLNTHNASILLSAANKSHYPQDDLPEIALAGRSNVGKSS
                     FINTILGRKNLARTSSKPGKTQLLNFFNIDNKLRFVDVPGYGYAKVSKSERAKWGKMI
                     EEYLTSRDNLRAVVSLVDLRHAPSKEDIQMYDFLKYYDIPVIVVATKADKIPRGKWNK
                     HESVVKKALNFDKSDTFIVFSSVERIGIDDSWDAILEQV"
     gene            9178..9921
                     /locus_tag="ACF4ZO_001143"
     CDS             9178..9921
                     /locus_tag="ACF4ZO_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486694.1"
                     /translation="MTQVAQGRSKGKSLLCHQCNALFVFIIFLILLAVLFGVRYRNSS
                     IEGIWRTTSIDQKLGDDFAKRLTGLHQSPLIDDSLLTSSQMILTVKNNNVDLSFSVQV
                     ERDIFVKRLAAYHQNELLKTLKENHLVVGDLSSKERQIIENSMPASHELEMILDQAFE
                     KLASQIGGKYNQKTGHLSAVVLKGKVNRILHTIDIKEEVAAGHTSFSKGLLTPNGYFD
                     YTRFGKKLELLGDEKIIFKKALKKSPSSV"
     gene            complement(9979..12078)
                     /locus_tag="ACF4ZO_001144"
     CDS             complement(9979..12078)
                     /locus_tag="ACF4ZO_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFD5486695.1"
                     /translation="MTHFSGKDPFVNMDDIFNQLMANMGGYRSENPRYLVNGREITPE
                     EFQHYRQTGQLPVATTKATNSQMLTPKADSVLTQLGTNLTQEARQGHLDPVIGRNKEI
                     QDTAEILARRTKNNPVLVGDAGVGKTAVIEGLAQAIVNGDVPAAIKNKEIVSIDISSL
                     EAGTQYRGSFEETIQNLIQEVKEAGNIILFFDEIHQIVGAGATSSDSGSKGLADILKP
                     ALSRGELTLIGATTQDEYRNTILKNAALARRFNEVKVNAPSAEDTFHILMGIRNLYEQ
                     HHHITLPDNVLKAAVDYSIQYIPQRSLPDKAIDLLDMTAAHLAAQHPVTDLKTLETEI
                     AKQKESQEKAVAKEDFEKALAAKTRIETLQKQIEQHNQSQNVTATVNDIAESVERLTG
                     IPVSNMRTNDLERLKGISSRLKSHVIGQDEAVAAVARAIRRNRAGFDDGNRPIGSFLF
                     VGPTGVGKTELAKQLALDLFGSKDAIIRLDMSEYNDRTAVSKLIGTTAGYVGYDDNNN
                     TLTERVRRNPYAIVLLDEIEKADPQIITLLLQVLDDGRLTDGQGNTINFKNTVIIATS
                     NAGFGQQDTETSESNIMDRIAPYFRPEFLNRFNSIIKFNHLQKENLEEIVDLMLAEVN
                     QTTAKKGISLTIADDAKAHLIDLGYNHAMGARPLRRIIEQEIRDRITDYYLDHPEVKK
                     LQAILKEGQLVIRQNDQ"
     gene            12457..13140
                     /gene="rpiA"
                     /locus_tag="ACF4ZO_001145"
     CDS             12457..13140
                     /gene="rpiA"
                     /locus_tag="ACF4ZO_001145"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009881270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004751 - ribose-5-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0009052 - pentose-phosphate shunt,
                     non-oxidative branch [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HFD5486696.1"
                     /translation="MKALKKIAGVTAAQYVTDGMTIGLGTGSTAYYFVEEIGRRVKQE
                     GLQVVGVTTSSVTSKQAEGLGIPLKSIDDIDSIDLTVDGADEVDKDFNGIKGGGAALL
                     MEKIVATPTKEYIWVVDASKMVEHLGAFKLPVEVVQYGADRLFRVFEKAGYKPSFRMK
                     GDSRLVTDMQNYIIDLDLGCIKDPVAFGHLLDGTVGVVEHGLFNGMVDKVIVASKDGV
                     TVLEAPKAG"
     gene            13217..14428
                     /locus_tag="ACF4ZO_001146"
     CDS             13217..14428
                     /locus_tag="ACF4ZO_001146"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008973 - phosphopentomutase activity
                     [Evidence IEA];
                     GO_process: GO:0009117 - nucleotide metabolic process
                     [Evidence IEA];
                     GO_process: GO:0043094 - cellular metabolic compound
                     salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HFD5486697.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDADKFFNAGVADTDSDTLGHISE
                     TAGLSVPNMVKIGLGNISRPIPLKTVPTEDNPTGYVTKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKIIREANKPYSGTAVIDDFGPHQMETGELIV
                     YTSADPVLQIAAHEDIILVEELYKICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRHDYAVSPFQDTVLNKLADAGVPTYAVGKINDIFNGSGITNDMGHNKSNSHGIDTL
                     IKTLQLPEFTKGFSFTNLVDFDANFGHRRDPEGYRDCLHEFDNRLPEIIANMKEDDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSASFTGNGLIPQGHFADISATVAENFGVDTA
                     MIGESFLGHLK"
     gene            14447..14887
                     /gene="arsC"
                     /locus_tag="ACF4ZO_001147"
     CDS             14447..14887
                     /gene="arsC"
                     /locus_tag="ACF4ZO_001147"
                     /EC_number="1.20.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922177.1"
                     /note="This arsenate reductase requires both glutathione
                     and glutaredoxin to convert arsenate to arsenite, after
                     which the efflux transporter formed by ArsA and ArsB can
                     extrude the arsenite from the cell, providing resistance;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0008794 - arsenate reductase
                     (glutaredoxin) activity [Evidence IEA];
                     GO_process: GO:0046685 - response to arsenic-containing
                     substance [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase (glutaredoxin)"
                     /protein_id="HFD5486698.1"
                     /translation="MEEITIYHNPNCGTSRNVLAMIRHAGIEPTIIEYLQTPPNRETL
                     IELLQSMGISARELLRTNVPEFEAHGLANQAVAEKDVINAMLTDLILINRPIVVTRKG
                     VKLCRPSETLLDILPVPLPSPYIKEDGEIVNPIEVKGEKDVIDD"
     gene            14871..15680
                     /locus_tag="ACF4ZO_001148"
     CDS             14871..15680
                     /locus_tag="ACF4ZO_001148"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HFD5486699.1"
                     /translation="MSLMTKINETKDFLVAKGIEAPEFGLILGSGLGELAEEVENPVV
                     IDYADIPNWGKSTVVGHAGKLVYGDLAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKA
                     LGCEGVLVTNAAGGIGYGPGTLMAITDHINMTGNNPLIGENLDEFGPRFPDMSDAYTK
                     VYRNKAHEVAEKMNIKLEDGVYMGLTGPTYETPAEIRAFKVLGADAVGMSTVPEVIVA
                     AHSGLKVLGISAITNFAAGFQSELNHEEVVEVTQHIKEDFKGLVKAILSEL"
     gene            16343..17056
                     /gene="deoD"
                     /locus_tag="ACF4ZO_001149"
     CDS             16343..17056
                     /gene="deoD"
                     /locus_tag="ACF4ZO_001149"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HFD5486700.1"
                     /translation="MSIHISAKKGDIADKILLPGDPLRAKFIAENFLEDAVCFNEVRN
                     MFGYTGTYKGHRVSVMGTGMGMPSISIYARELIVDYGVKTLIRVGTAGAIDPEVHVRE
                     LVLAQAAATNSNIIRNDFPEFDFPQIADFGLLDKAYHIAREMGVTTHVGNVLSSDVFY
                     TNMPERNMALGKLGVKAIEMEAAALYYLAAQHHVKALGIMTISDNLNDPTEDTTAEER
                     QTTFTDMMKIGLETLIAND"
     gene            17049..17837
                     /locus_tag="ACF4ZO_001150"
     CDS             17049..17837
                     /locus_tag="ACF4ZO_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytR family transcriptional regulator"
                     /protein_id="HFD5486701.1"
                     /translation="MTNNQTLDILLDVYAYNHAFRIAKALPNIPKTVLYLLEMLKERR
                     ELNLAFLVEHAAENRTIEDQYHCSLWLNQSLEDEQIANYILDLEVKVKNGAIIDFVRS
                     VSPILYRLFLRLITSEIPNFKAYIFDTKNDQYDTWHFQAMLESDHEVFKAYLSQKQSR
                     NVTTKSLADMLTLTSLPQEIKDLVFLLRHFEKAVRNPLAHLIKPFDEEELHRTTHFSS
                     QAFLENIITLATFSGVIYRREPFYFDDMNAIIKKELSLWRQSIV"
     gene            complement(17917..18822)
                     /locus_tag="ACF4ZO_001151"
     CDS             complement(17917..18822)
                     /locus_tag="ACF4ZO_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFD5486702.1"
                     /translation="MRIQQLHYIIKIVECGSMNEAAKQLFITQPSLSNAVKDLEMEMG
                     ITIFNRNPKGITLTKDGVEFLSYARQIIEQTSLLEDRYKNHNTGRELFSVSSQHYAFV
                     VNAFVSLLKRTDMTRYELFLRETRTWEIIDDVKNFRSEIGVLFINDYNRDVLTKLFDD
                     NHLTASPLFKAQPHIFVSKSNPLATKSLLSMDDLRDFPYLSYDQGIHNSFYFSEEMMS
                     QMPHNKSIVVSDRATLFNLMIGLDGYTVASGILNSNLNGDQIVAIPLDVPDEIDIVFI
                     KHEKANLSKMGERFIEYLLEEVTFD"
     gene            19044..19580
                     /locus_tag="ACF4ZO_001152"
                     /pseudo
     CDS             19044..19580
                     /locus_tag="ACF4ZO_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990141.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            19857..20549
                     /gene="pyrF"
                     /locus_tag="ACF4ZO_001153"
     CDS             19857..20549
                     /gene="pyrF"
                     /locus_tag="ACF4ZO_001153"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004590 - orotidine-5'-phosphate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0044205 - 'de novo' UMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HFD5486703.1"
                     /translation="MKEERPIIALDFSSFEETKAFLDLFPAEEKLYVKIGMELYYAQG
                     PDIVRYIKSLGHNVFLDLKLHDIPNTVRAAMAVLKELDIDMATVHAAGGVEMLKAARE
                     GLGQGPTLIAVTQLTSTSEDQMRGDQNIQTSLLESVLHYSKGAAKAQLDGVVCSAQEV
                     EAIKAVTPTGFTCLTPGIRPKGSNIGDQKRVMTPNQARRIGSDYIVVGRPITQAKDPV
                     AAYQAIKAEWAG"
     gene            20607..21236
                     /gene="pyrE"
                     /locus_tag="ACF4ZO_001154"
     CDS             20607..21236
                     /gene="pyrE"
                     /locus_tag="ACF4ZO_001154"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004588 - orotate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009220 - pyrimidine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HFD5486704.1"
                     /translation="MTLASQIATQLLDIKAVYLKPEDPFTWASGIKSPIYTDNRVTLS
                     YPKTRDLIENGFVETIRAHFPEVEVIAGTATAGIPHGAIIADKMTLPFAYIRSKPKDH
                     GAGNQIEGRVLKGQKMVIIEDLISTGGSVLDAAAAASREGADVLGVVAIFTYELPKAS
                     QNFKEAGIKLITLSNYTELIAVAKLQGYITNDGLHLLKKFKEDQVNWQQ"
     gene            21433..22887
                     /locus_tag="ACF4ZO_001155"
     CDS             21433..22887
                     /locus_tag="ACF4ZO_001155"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HFD5486705.1"
                     /translation="MTYQDATAMAIAVQTGQTTPLELVTQAIYKAKKLNPTLNAITSE
                     RFEAALEEAKQRDSSGLPFAGVPIFLKDLGQELKGHSSTSGSRLFKEYQAAKTDLFVK
                     RLEALGFIILGRSNTPEFGFKNISDSSLHGPVNLPKDNTRNAGGSSGGAAALVSSGIS
                     ALAPASDGGGSIRIPASFNGLIGLKPSRGRMPVGPGSYRSWQGASVHFALTKSVRDTR
                     NLLYYLQMEQMESPFPLATLTKDSIYPSLQRPLTIAFYQRLSDGSPVSLDTAKALKQA
                     VTWLREQGHQLVELEEFPVNMTEVIRHYYIMNSVETAAMFADIEDTLGRPMTKDDMET
                     MTWAIYQSGKDIPAWRYSQVLQKWDTYSATMASFHETYDLLLTFTTNTPAPKHGELVP
                     DSKLMANLAQAEIFSSEEQFNLVETMFGKSLAINPYTALPNLTGQPAISLPTYETKEG
                     LPMGIQLIAAKGREDLLLGIAEQFEAAGLLKIPQ"
     gene            23005..23868
                     /locus_tag="ACF4ZO_001156"
     CDS             23005..23868
                     /locus_tag="ACF4ZO_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HFD5486706.1"
                     /translation="MKKSVTLLSIGLASLLLAACAPHKSQKSSWNTIKEKGVLKVATP
                     GTYQPTSFYNDNNELVGYEVDMVKEIGKRLNIKVKFVETGFDQAFTSVDSGRVDISLN
                     NFDITPKRQKKYNISTPYKYGVGGMIVRADGSSNMAKKDLSDWKGKKAAGASGTEYMK
                     VAQKQGAELVTYDNVTGDVYLNDVANGRTDFIPNDYPAQKLFVDYMLSQNPNLNVKMS
                     DVQYNPTEQGIVMNKKDDSLKKKIDAVIKDMIKDGSLKKISETYYAGQDLTKPFGKDK
                     KIPVIDTKDVN"
     gene            23897..24547
                     /locus_tag="ACF4ZO_001157"
     CDS             23897..24547
                     /locus_tag="ACF4ZO_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HFD5486707.1"
                     /translation="MINIPLMKDSLGFVLSGLPYTLGISLLSFFTGLFLGLGLALLGR
                     SRQPLIHYLVRAYISIMRGVPMIVVLFVLYFGLPYYGLELPALLCAYLGFSMVSAAYI
                     SEVFRSSIEAIDKGQWEAAKALGLPYSLMVKKIILPQAFRIAVPPLGNVIIDMVKSSS
                     LAAMITVPDIFQNAKIIGGREWDYMSMYILVAFIYWLIAFLLERYQEFLENKLALV"
     gene            24680..25333
                     /locus_tag="ACF4ZO_001158"
     CDS             24680..25333
                     /locus_tag="ACF4ZO_001158"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004844 - uracil DNA N-glycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HFD5486708.1"
                     /translation="MAHSIWHEKIKSFLPEHYYGRINHFLDEAYASGLVYPQRENVFK
                     ALQVTPLEETKVLILGQDPYHGPKQAQGLSFSVPEEISAPPSLINILKELADDIGPRD
                     HHDLSTWASQGVLLLNACLTVPAGQANGHAGLIWEPFTDAVIKVLNEKDSPVVFILWG
                     AYARKKKAFITNPKHHIIESPHPSPLSSYRGFFGSKPFSRTNAMLEKEGMIGIDWLQ"
     gene            25491..26759
                     /locus_tag="ACF4ZO_001159"
     CDS             25491..26759
                     /locus_tag="ACF4ZO_001159"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HFD5486709.1"
                     /translation="MILIKNGRVMDPKSQRDQVADVLIDGKQIVKIASAIECQEAQVI
                     DASGLIVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGVTTVVMMANTNPVISDVE
                     TLQEVLASAAKEKIHIYTNASVTQAFNGKDVTDFKALLEAGAVSFSDDGIPLESSKVL
                     KEAFDLANANQTFISLHEEDPQLNGVLGFNEGIAEEHFHFCGATGVAEYSMIARDVMI
                     AYDRQAHVHIQHLSKAESVQVVAFAQQLGAKVTAEVSPQHFSTTEDLLLTAGTSAKMN
                     PPLRTQRDRLAVIEGLKSGVITVIATDHAPHHKDEKAVDDMTKAPSGMTGLETSLSLG
                     LTHLVEPGHLTLMSLLEKMTLNPALLYGFDAGYLAENGPADLVIFADKQERLITENFA
                     SKASNSPFIGNKLKGVVKYTIADGEVVYPN"
     gene            complement(26817..27458)
                     /gene="plsY"
                     /locus_tag="ACF4ZO_001160"
     CDS             complement(26817..27458)
                     /gene="plsY"
                     /locus_tag="ACF4ZO_001160"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009881256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008374 - O-acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006654 - phosphatidic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HFD5486710.1"
                     /translation="MKLLLFITIAYLLGSIPTGLWIGQYFYHINLREHGSGNTGTTNT
                     FRILGVKAGTATLAIDMFKGTLSILLPIIFGMTSISSIAIGFFAVLGHTFPIFANFKG
                     GKAVATSAGVLLGFAPLYLFFLASIFVLVLYLFSMISLASVVSAIVGVLSVLTFPAIH
                     FLLPNYDYFLTFIVILLAFIIIIRHKDNISRIKHHTENLIPWGLNLSKQVPKK"
     gene            27593..>27918
                     /locus_tag="ACF4ZO_001161"
     CDS             27593..>27918
                     /locus_tag="ACF4ZO_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFD5486711.1"
                     /translation="MTKKEITINNYNDDAIQVLEGLDAVRKRPGMYIGSTDATGLHHL
                     IWEIVDNAVDEALSGFGDDIKVVINKDGSVSVADSGRGMPTGQHAMGIPTVQVIFTIL
                     HAGGKFG"
BASE COUNT         8650 a         5015 c         5762 g         8491 t
ORIGIN      
        1 cctgtgacca actatttaac acccagctag atcagaaagc tttagctcaa aaggctaagt
       61 tcgcctcagg atcatcttct cgttcttttt ttggcccagt tgctgcttgg gacaaagata
      121 gtggtgctat ttacaaggtt gagactgact tgaaaatggc catgattatg ctggtcttaa
      181 atgctgcgaa aaagccaatt tctagccgag agggcatgaa gttatgccgc gatacctcaa
      241 ctacatttga tgaatgggta gaacaatcgg caatcgatta ccaacatatg cttacctatc
      301 tcaaaactaa taattttgag aaagttggtc agttaacaga agctaatgcc ttggccatgc
      361 atgccacgac aaagacagcc aatcctcctt tttcttacct aacaaaagag tcttaccagg
      421 ctatggaggc tgtgaaagaa ctgcgtcaag aaggttttgc ttgttatttt accatggacg
      481 caggtccaaa tgtgaaggtc ctatgtttag aaaaagactt ggctcaacta gcagaacgac
      541 ttggcaagaa ctaccgtatt atcgtttcaa aaacaaagga tttaccagat gtctaattat
      601 tgtgtgcaaa caggtgggaa actatacctc acaggcgaat atgctatctt aacaccagga
      661 caaaaagcct taattcactt tattccactg atgatgacag cagaaattag cccagcagcc
      721 catattcaat tagcttcaga tatgtttgcc cataaagcgg gcatgacacc cgatgcctct
      781 tatgcactga ttcaagcaac ggttaaaacc tttgctgatt atctaggaca gtcaattgac
      841 caactggagc cattttccct aatcataacg ggaaaaatgg agcgcgatgg caaaaaattt
      901 ggcattggtt caagtggtag tgtcaccctc ttaaccttaa aggccttatc ggcctattat
      961 cagatcactt taaccccaga gttactcttt aaactagcgg cttatacctt gcttaagcaa
     1021 ggagataatg ggtctatggg ggatattgcc tgtatcgctt accagacttt agtcgcctat
     1081 acctcctttg accgagaaca ggtcagtaac tggctgcaga ccatgccctt aaaaaaactt
     1141 ctcgtcaaag attggggtta ccatatccaa gtcattcaac cagccctgcc ttgtgacttt
     1201 ttggttggct ggactaaaat acctgctatt tcaaggcaga tgattcaaca agtgacagcg
     1261 agcattaccc cagctttctt aagaacaagt taccagctaa cgcaatcagc tatggtagct
     1321 ttgcaagaag gtcataagga agaactcaag aaaagtttag caggagcaag tcatctccta
     1381 aaagagcttc atccagctat ctaccatcct aagctagtaa ccttggtagc tgcttgtcag
     1441 aagcaagatg ctgttgctaa atcttcaggt tctggtggtg gagattgtgg catcgcgctt
     1501 gcctttaatc agaatgccag agataccctt atttccaaat ggcaagaagc tgatatcgca
     1561 ttactttatc aagaaaggtg gggagagaat gaccaaccgt aaagatgatc acatcaaata
     1621 tgccctcaag taccaatcgc cttataatgc ttttgatgac atagaactca tacatcattc
     1681 cttacctagc tatgatttgt ctgatattga tctcagtact cattttgccg ggcaagactt
     1741 cgactttccc ttttacatca atgccatgac aggaggaagt caaaaaggca aagctgtcaa
     1801 tgaaaaattg gccaaagtag cagcagcaac agggattgtc atggtgacag ggtcttatag
     1861 cgctgcttta aaaaatccta acgacgattc ctatcgttta catgaggtgg cagataactt
     1921 gaaactagcc acgaatattg gtctagataa acctgtggcg ctaggacaac aaacggttca
     1981 agaaatgcag cccctctttt tacaggttca tgtgaatgtg atgcaagagt tgctgatgcc
     2041 agagggtgag cgcgtctttc atacctggaa aaaacacctc gctgaatacg ctagtcaaat
     2101 accagttcct gtcattctca aagaagttgg ttttggcatg gatgtcaata gtatcaagct
     2161 agcacatgac ctaggcattc aaacctttga tatttcagga agaggaggga cctcatttgc
     2221 ctatattgaa aatcaaagag gaggagaccg ctcttactta aacgattggg gacaaaccac
     2281 cgttcagtgc ttgctaaatg cacaaggact gatggaccaa gtggaaatct tagcttcggg
     2341 tggtgtcaga caccccttgg acatgattaa atgtttcgtc ctaggagcac gtgcagtggg
     2401 actctcacgc accgttttag aattggtcga aaaataccca accgagcgtg tgattgctat
     2461 cgttaacggc tggaaagaag aattaaaaat cattatgtgt gctcttgact gtaaaactat
     2521 taaagaatta aagggagtcg actacttact atatggacgc ttgcagcagg tcaattaggc
     2581 ttcatcacct ctacaatagt gtcacctact acaaagatga tagagctttt ttagaacata
     2641 atataaaata tttataaata cctcatcaaa ctcagaatag agtagatgag taaatagagt
     2701 atgttatgga gactatttct aagacttgta tgtatagaaa caaagattaa acacccatgt
     2761 aaaccaattg tttacatggg tgattgcctt atattagttg tttaaatcta agactgtctt
     2821 agctgagata agtaaaaatg tgctttttct agatttattg gtttatcagc tagtaaagca
     2881 ttaactaaag gagtaatttc gtcttgggtt gcccccgcca aaagagctaa tgatttcgca
     2941 tgtagtttca tgtgaccagc ttggatgcca gatgaggtca gagcttttag tgcagcaaag
     3001 ttttgagcta accccacaga tgcaatcaat tgggctaatg ttttggcatc aggttgatta
     3061 agaagatcat gtgcgataga aacagtaggg ttaagcccga tagatccccc cttactagca
     3121 ataggcatag ggagggtcat ttggccaagc agaacttgtt tatcttggtc aaaatgccac
     3181 tgactaagtc cttgatagct accatttctt gaggcataag catgggcccc tgcttcaata
     3241 gcacgccagt catttcctgt ggctattacc actgcatcaa taccattaaa aataccttta
     3301 ttatgagtag tagcccggta aggatctact tgagctagtc ggctggctag ctctattttt
     3361 tgagctaact gtagggattt tgttttatcg cgatctaaaa ggcgcacggg aatctcacaa
     3421 ctagtagtaa caagcgactc tgttgcgtaa ttagataaaa tcgccattag acaatgcccc
     3481 ttagacagtc ttgttaaatc aggaacaaga gcttccatca tagtattgac catatttgct
     3541 cccatagctt cttgggtatc aacagtcaga tagaaaatca aaaactctcc tttttcttcc
     3601 aaatgaatgg ttctagcgcc tccacctctt ttaacaatgg aaggataagc tttatttgcc
     3661 aatgcaatta gcttttttgt tttatgaagg atggcggctt tagcgttatc tatttggtcg
     3721 atatcgtaaa gaacaatttg accaatcatt tgtcggttta gggtttgagc tttaaaacca
     3781 cctgagcgtt tgattagttt tgctgcgaaa gatgctgcag caacaacaga aggttcttcc
     3841 gtgacaaaag gcatctgata agttgagccg ttgacaagaa aatcaggagc tatgctaaag
     3901 ggcaaagcca atcgtcctaa gacgttttca gtcatttgat tagctgtttg gataggcaaa
     3961 agaatgtctg ttttgagttg atttaagttt tcagcattaa gtagtttaaa tttttcgata
     4021 agttggaggc gttcttcgaa tgttttcttt gaaaaaccgc tccagttaag attagttttt
     4081 gtcattggta cgatagatcc tttgatgctc cttgatggct gttagagcaa attttccagt
     4141 taagtaaatg tcaaaattgg cattaccatt atcatctaat tggacttgtt cgtagaaaag
     4201 gtcttcgtat ttagaaacgg aaagacgtgt tcgttgatcc agtaaagttt gtcgattagt
     4261 cattaacatt ttatcgtatc cagcaactaa ctgaccggaa taaaattcac ttacggcacc
     4321 ggaaccatag ctaaaaaaac caattttatc tccagattgt aatactttac tattttcaag
     4381 taaagataac aatcctagat aaagtgagcc agtataaata tttccaattt gtttgctata
     4441 agtaatagaa gcttgaaagg cttctattag tttttccctg tgttcaggag gtactgtgtt
     4501 atccataatg ttatttagac cttttagggc taacttggga aatggaatat ggaaacaaac
     4561 tgcagcaaaa tcagataact gaaggttttc tcttttctga taagcttgcc acgtggtttc
     4621 taagcaattg agatattgct tggtagagta aataccatca acataaggtg tgaaactata
     4681 gttaggcctc caaaagtcca taatatccct agtttgagcc acattatctt catttagagc
     4741 aagaatacga gggttagtag ttaccaaaag agcaatacta ccagagcctt gagttgattc
     4801 gccaggagat cctacaccgt atctagcaat atcactagca ataacaagga cacgagaatc
     4861 tggcttagaa gccacatgca gtttagcata gtctagagca gcagttgcgc tatagcaggc
     4921 ttgttttact tcaaaggaac gtgcaaaagg ctggatacca actaagtgat gtacatagat
     4981 agctgatgcc tttgactgat cagtactcga ttcagttgcc aaaataacca tatcaatctt
     5041 agatcgatct tcgtcggtta aaatttgatc tgctgcagaa gcagctaaag taataatgtc
     5101 ttcagtgatt ggtgccacac taaaagactc aatgagtagc ccttgactaa attttgctgg
     5161 atccacttgg cgtgcaagcg ctaaatcttc caatttcaag acatattgac tggttgcaaa
     5221 accaatctta tcaattccaa ttgtcatatt tgtccttctt ttagttattt ttatagtctt
     5281 acccattcta tcacatttta ctgcaaaatt agactgataa agttatttgt tttatccttt
     5341 aatagttaaa atgttcatga ccacatgaag tttttcgaat gtttatttat tctggtattt
     5401 tttggtaaaa ttagttagaa tagtatgaag tatgcttaca gaaaggttat tagagatgac
     5461 aaaagctgac cagattttta aagctaatat tcaaaaaatt ataaatgaag gatcattgag
     5521 tgagcaagca cgtcctaaat ataaagatgg tcgaacagct cattctaagt atattactgg
     5581 ggcgtttgct gaatatgatt tagctaaagg agagtttccc atcacaactt tacgacctat
     5641 tccaattaaa tctgctataa aggaattatt ttggatatat caagatcagt ctaacagttt
     5701 agatgtgcta gaagctaaat ataatgttca ttattggaat gaatgggaag ttgaccagac
     5761 acgtactatt gggcaacgtt atggtgctgt agttaaaaaa catgatatca tctcaaaaat
     5821 actaaagcaa ttagcagaaa atccttggaa tcgtcgtaat gtcatttctc tctgggacta
     5881 tgaagcattt gaggagacaa aagggttgtt gccatgtgcc tttcaaatca tgtttgatgt
     5941 tagacgtgta ggggaagatc tttatttaga tgctagtttg acgcaacgtt ctaatgacat
     6001 attagttgct catcacatca atgccatgca atacgttgcc ttgcagatga tgattgctaa
     6061 acattttgga tggaaaatag gtaagttctt ttattttgtt aacaatttac atatttatga
     6121 caaccaattt gatcaggctc aagaattact aaaacgacag ccagttgcca gtcagcctaa
     6181 gcttgtttta aatgttccag atgggactaa tttctttgat attaaaccag atgattttga
     6241 attacaaaat tatgatccag tgaagcctca gttgcacttt gaccttgcta tttaaacttt
     6301 atttagattt tttgtgagca ttttgttcat aaatttggta aaataaatag agtttaaaat
     6361 gaaggaaata attaatgaca aaggaaatta ttgctatttg ggcagaggat gaagcagggc
     6421 ttattggtgt tgcgggtaag ttaccatggt atttaccaaa agagttagaa cattttaaaa
     6481 agacaacgct acatcaagca atcttaatgg gccgtgtgac ttttgaagga atgaattgca
     6541 aaagactttc tcaacgtcaa acccttgtca tgacaagaaa tagagattat caagtagatg
     6601 aggtgttgac aatgactagt attgaaaaag tcttggagtg gtaccatgcg caggataaaa
     6661 cactttatat cattggtggg aataaggttt tagaagcgtt taatggttat ttcgatcgta
     6721 tcataaaaac agttatccat catcgtttta aaggagatac ctaccgacca aatctagatt
     6781 ttagtcattt cacgcaagaa agccaaacgt tctatgctcg agacgctaaa aatccttatg
     6841 attttaccgt tactgcttta aaacacaaat agtctgagga gatgataagc gatgcaacgt
     6901 agtatttttg gagtatttac ggcttttttg tgcgtgattt gtgttctttg tgccatccca
     6961 gcttttaaaa agaatcgtta tggcttagga agtctgttct tattaaatgc gtttactaat
     7021 ctggttaata gtattcacgc cttctatggt acattgtttt gagatgcgac ttgcaaagac
     7081 agcactggtg aagatttagc tatcaagcaa gaatcaccaa aaaccaatac aacacattga
     7141 ctaatattaa aattcagtaa aagataagag aaagtaagag aattataaga aatggcagga
     7201 agtagaacta acgatattaa agtatactgt tcattttgtg gtaaaagcca ggatgacgtt
     7261 aaaaaaatta tcgcaggaaa taatgttttc atctgcaatg aatgcgtagc tttatcacaa
     7321 gaaattataa aagaagaatt ggctgaaaaa gtccttgccg atttgacaga agttccaaaa
     7381 ccaaaagagc tccttgatgt tttaaatcaa tatgtggttg gtcaagatcg tgctaaacgt
     7441 gctttatcag ttgctgtgta caatcattat aagcgtgtct cgtttacaga aagtcgtgat
     7501 gacgatgatg tggatttaca aaagtctaac attttgatga ttggaccaac aggttcagga
     7561 aaaaccttct tagcacaaac tctggctaaa agcctcaatg taccatttgc tattgcagat
     7621 gcaacttctt tgactgaagc agggtatgtt ggagaagatg tggaaaatat tttactcaaa
     7681 ctgattcagg ctgctgacta taatgtcgaa cgagcagagc gtggtattat ttatgttgat
     7741 gaaatagata agattgctaa aaaaggtgag aacgtatcta tcacacgtga tgtatctggt
     7801 gaaggtgtac agcaagccct tcttaaaatt attgaaggta cggtagcaag tgttccccca
     7861 caaggtgggc ggaagcaccc taatcaagaa atgatccaaa ttgatacaaa aaatatcttg
     7921 tttattgttg gcggggcttt tgatggcatc gaggagattg ttaaacaacg tttaggtgaa
     7981 aaagttattg gttttggtca aaacagccgt aaaattgatg acaatgcttc ttatatgcaa
     8041 gaaattattt cagaagatat tcaaaagttt gggcttattc cagaatttat tggccgctta
     8101 ccagttgtgg cagcccttga acaactaaac acatcagatt tgattcgaat cttaacagag
     8161 ccaaggaatg ctcttgtcaa gcaatatcag gcccttcttt cctatgatgg ggttgaatta
     8221 gaatttgata aagcagctct tgaagctatc gcaactaaag ccattgaacg taagacagga
     8281 gcacgtggtc ttcgttctat tatcgaagaa acgatgcttg acatcatgtt tgaaattcca
     8341 agccaagaag atgtcacaaa agtgcgtatc accaaggctg ctgtcgaagg caagtcaaaa
     8401 cccgttttag agacagctta aggagaaata atggctgaag aacaagtctt aaatacccat
     8461 aacgcctcaa ttttattgag cgctgccaat aaatctcatt acccccaaga tgatttgcca
     8521 gaaattgccc ttgctggacg ttcaaatgtt ggtaaatcaa gttttattaa taccatattg
     8581 gggcgcaaaa atttggcaag aacctcaagc aagccaggaa aaacccaact attaaatttt
     8641 ttcaatattg ataacaagct tagatttgtg gatgtccctg gttatggcta tgccaaggtt
     8701 tctaaaagtg aacgggccaa atggggaaag atgatcgaag aatacttaac cagcagagac
     8761 aatctgcgtg cagtcgtgag tttggttgat ttacgtcatg ccccttcaaa agaagatatt
     8821 cagatgtatg actttttgaa gtactatgac attcctgtta ttgttgtggc aaccaaagca
     8881 gataagattc ctcgtggcaa atggaacaaa catgagtctg tggtcaagaa agctttgaat
     8941 tttgacaaat ctgatacttt tatagtattt tcttcggtag aacgtattgg tatcgatgat
     9001 tcttgggatg ctattttaga gcaggtctag cgataggtgt tgatttatct atgctaaaac
     9061 attctcagta gagggtgttt ttctgatcga aaacataaaa aatcatagtt aggtttaccg
     9121 attttacttg acgccttaat gatgacatgc tagtatttta tattaaggag atgagtcatg
     9181 acacaagtag cccaagggcg ctctaaagga aagtcattgt tatgccatca atgcaatgcc
     9241 ctttttgtat ttattatttt tcttatcttg cttgctgtac tttttggtgt tcggtatcgt
     9301 aatagctcta ttgaaggtat ctggcgaaca acaagcattg atcagaagtt aggcgatgat
     9361 tttgctaaac gtcttactgg tttgcatcag agccctctta ttgatgatag tttattaacg
     9421 tcatctcaga tgatactaac agttaaaaat aacaacgttg acttgagttt tagtgttcaa
     9481 gttgaacgag acatttttgt caaacgttta gctgcttatc accaaaatga attattaaag
     9541 acattaaagg aaaatcattt agttgttggt gacttgagta gtaaagaacg ccaaattatt
     9601 gagaatagta tgccagctag ccatgaatta gaaatgattt tagatcaagc ttttgagaaa
     9661 ttagcttctc agatcggagg caaatataat caaaaaacag gacatttatc tgctgttgtt
     9721 ctcaaaggaa aagttaatcg tattttgcac accattgata tcaaagaaga agtagcagcg
     9781 ggacatactt ctttttcaaa aggattgctc acacctaatg gttattttga ttacaccaga
     9841 tttggaaaga aacttgagtt attaggcgat gaaaaaatta tttttaaaaa agcgctaaaa
     9901 aaaagtccgt caagtgtata acgtagtcac aagacggatt ttttcatgtt ttgaaaatta
     9961 ttcaattgaa gaagtttatt actgatcgtt ttgcctaatc actagttgtc cttcttttag
    10021 gattgcctga agttttttga cttctggatg gtcaagataa taatcagtta tacggtcacg
    10081 aatttcctgt tcgataatac gtcgtaatgg acgagctccc atagcgtgat tgtaccctaa
    10141 atctatcaaa tgagctttag cgtcatcagc aatcgttaaa ctaatacctt tttttgcggt
    10201 ggtttgattt acttcagcta gcattaaatc aacaatttct tctaaatttt ctttttgcag
    10261 atgattaaat ttaatgatac tattaaaacg gttcaaaaac tctggtctga aataaggtgc
    10321 aatgcgatcc ataatgttag actcagaagt ttccgtatct tgttggccaa aaccggcatt
    10381 tgatgtagca ataataacgg tatttttaaa gttaatagta tttccttgtc catctgtcaa
    10441 tcgtccatca tctaacactt gtagaagaag tgtaatgatt tgaggatcag ctttttcaat
    10501 ttcatctagt aagacaatag cataagggtt acgacgaaca cgctcagtta gggtattatt
    10561 attatcatcg tagccaacat aaccagccgt tgtcccaatc aattttgaca cagcagtgcg
    10621 atcgttatat tcggacatat caagtcgaat aatagcatct ttggaaccaa ataaatcaag
    10681 tgctaattgt ttagctaact ctgttttacc aacaccagtt ggacccacaa aaaggaaaga
    10741 acctattgga cggttaccat catcaaaacc tgctcgattt cgtcgaatag cacgtgctac
    10801 tgctgcgaca gcctcatctt gtccgatgac atggcttttt aagcggctgc taattccttt
    10861 gagcctttct aaatcattag tcctcatgtt agagacagga ataccagtta agcgctctac
    10921 agactctgcg atatcattga ctgtagcagt aacattttgg ctttggttat gttgctcaat
    10981 ttgcttttgt aatgtttcaa tccgtgtttt tgctgctaaa gctttttcaa agtcttcttt
    11041 ggcgacagct ttttcttgac tctctttttg tttagctatt tcagtttcga gtgtttttaa
    11101 gtcagtgacc gggtgttgcg cagctaaatg agcagctgtc atatccagta agtcaattgc
    11161 tttatctggc aggctacgct gtgggatgta ttgaatagaa taatcaacag cagcttttag
    11221 aacattatca ggaagggtaa tatggtggtg ttgttcataa agattacgaa tacccattaa
    11281 aatgtgaaaa gtatcttcag ctgatggtgc attcacttta acttcattaa agcgacgagc
    11341 aagagcagca ttttttaaaa tagtattgcg gtattcgtct tgagtagtag caccaatcag
    11401 tgttaattct cctcgtgaca aggctggttt aagaatatct gcaagtccct ttgagcctga
    11461 atcactgctt gtggcaccag caccaactat ttgatgaatt tcatcaaaaa ataagatgat
    11521 attcccagct tcttttactt cttgaatcaa gttttgaatg gtctcttcaa aggagccacg
    11581 atactgtgta ccagcttcaa gactagaaat gtcaattgat acgatttcct tgtttttaat
    11641 agcggctggg acatctccat taacaatggc ttgagctaaa ccttcaatga ctgcagtttt
    11701 accgacacca gcatctccga caaggacagg attattttta gttcgtcgtg ccaagatttc
    11761 agcggtatct tgaatttctt tgttacgacc aatgacgggg tcaagatgcc cttgacgagc
    11821 ttcttgtgtt aagttagttc cgagttgagt caatacacta tcagctttag gtgttaacat
    11881 ttgagaattt gttgctttgg ttgttgctac agggagttgt cctgtttgac gatagtgttg
    11941 gaattcttcg ggagttattt cgcgaccgtt aacgagatag cggggatttt cgctacgata
    12001 accacccatg tttgccatta attggttgaa aatatcatcc atatttacaa aaggatcttt
    12061 accagaaaaa tgtgtcatat cagttacctc gcaataaaaa aatagactat aagatgtttg
    12121 taagcagtcg cagaatcgtt gttaggattt cacatgatag gaaatccttt gctaatagaa
    12181 tgattcagac attattttta ctcatcttat agtattatta taatcaaaag gtcagtaaag
    12241 gtcaaacaaa aacacttgat tttcaaaaag ctaaataaac acgaaaagta agtgcttata
    12301 tgatgacttt agaataaatc ataagtttta aaaagatcat cctattctat agcacttagg
    12361 ctgtcaatga gagaaaaaca aatgttttca ttaacaagtt ggcgctctca tggtataata
    12421 aagtgctaag acgcaattct attataaggg ggaatcatga aagcactcaa aaaaattgcc
    12481 ggtgttaccg ctgcgcaata tgtgactgat ggcatgacca ttgggcttgg aactgggtca
    12541 acggcttact attttgttga ggaaattggc cgtcgcgtaa agcaagaagg actgcaagtg
    12601 gttggtgtga ccacgtcaag tgtgactagc aagcaagcag aaggcttagg cattccttta
    12661 aaatcgatag atgatattga tagcattgac ctcaccgtag atggtgctga tgaagtggat
    12721 aaggatttca atggaatcaa gggtggtggt gcagccttac taatggaaaa aattgttgca
    12781 acaccaacaa aagaatacat ctgggttgtt gatgcttcta aaatggtaga gcatctgggt
    12841 gcctttaagt taccagtcga agtcgttcaa tatggtgctg atcgtttgtt ccgtgtcttt
    12901 gaaaaagctg gttacaaacc gtcttttcgt atgaaaggtg atagtcgttt ggtgacagac
    12961 atgcaaaact atattattga tcttgatttg ggttgtatta aagatcctgt tgcttttggt
    13021 cacctgttag atggaacagt tggtgttgtg gaacacggtc tctttaatgg tatggttgat
    13081 aaggtgattg ttgctagtaa agacggtgtt actgttttag aagcgcctaa agcaggctag
    13141 tcttagcata taacagtgtt aatatatttt ataggtattg gggagtcaac cgtaacctcc
    13201 cctagattgg agacttatgt caaaatttaa tcgtattcac ttggttgttt tagactctgt
    13261 cggtattggt gcagcaccag atgctgacaa attctttaat gctggtgtag ctgatacaga
    13321 ttctgacacc ctcggtcata tttcagaaac agcaggctta tcggttccaa atatggtaaa
    13381 aattggactt ggaaacattt ctcgtccaat accactaaaa actgttccaa cagaagataa
    13441 tcctactggt tacgtgacca aattggaaga agtatctctt ggaaaagata ccatgacagg
    13501 ccattgggaa attatgggct tgaacattac ggaacctttt gacactttct ggaatggttt
    13561 cccagaagag attttaacta agattgagga gttttctggc cgcaaaatca ttcgcgaggc
    13621 caacaaacct tattcaggaa ctgctgttat tgatgatttt ggtccgcatc aaatggaaac
    13681 aggtgagttg attgtttaca cctcagcaga cccagtgctt caaattgcag cccatgaaga
    13741 cattattctt gtggaagagc tttacaagat ttgtgaatac gctcgctcca tcacgcttga
    13801 acgccctgcc cttttaggcc gtattattgc gcgtccttat gtaggcgaac caggaaactt
    13861 tacacgtacg gctaaccgtc atgactatgc agtgtctcct ttccaagata ccgttttgaa
    13921 caaactggct gacgcaggtg tcccaactta tgctgttggt aagattaatg acatctttaa
    13981 tggttcaggt attacaaacg acatgggaca caataagtcg aacagccatg gtattgacac
    14041 gcttattaag actcttcaat tacctgagtt tactaaggga ttctccttta ctaacctcgt
    14101 tgattttgat gccaactttg gtcatcgtcg tgacccagag ggttatcgcg actgcttgca
    14161 tgaatttgac aatcgcctac ctgaaatcat cgcaaatatg aaagaagacg atttgcttct
    14221 catcactgct gaccatggta atgacccaac ctatgcaggc accgaccaca ctcgtgaata
    14281 cattccattg cttgcctact ctgcatcctt tactggaaat ggtcttattc cacaagggca
    14341 ttttgcagat atttcagcga ctgttgcaga aaattttgga gttgatacag ccatgattgg
    14401 ggagtcattc cttggtcact taaaataaga aagttagtaa ttgataatgg aagaaatcac
    14461 gatttatcat aatccaaact gtggcacttc acgtaatgtt cttgccatga ttcgccatgc
    14521 aggtattgag cctactatta ttgagtattt gcagacgcca cctaatcggg agactttaat
    14581 tgagctctta caatcgatgg gaatctctgc gcgagaactc ttgcgaacca atgttcctga
    14641 atttgaggct catggattag caaatcaagc agtagctgag aaagacgtta ttaatgccat
    14701 gttgacggat ctaattttga tcaatcgtcc tattgttgtg actcgcaaag gagtaaaact
    14761 ttgccgtcct tctgagacct tactggatat tcttcctgtt cccctgccta gtccttatat
    14821 taaagaggat ggcgagattg tgaaccctat tgaggtaaaa ggagaaaaag atgtcattga
    14881 tgactaaaat taacgaaaca aaagactttt tagttgctaa aggaattgaa gctccagaat
    14941 ttggattaat tctgggttca ggccttggtg aacttgctga agaagtagag aatcctgttg
    15001 ttattgatta tgcagatatt ccaaactggg gcaaatcaac agttgttggc catgctggaa
    15061 aattagtcta cggtgattta gctggtcgta aagtacttgc cctacaaggt cgtttccatt
    15121 tttacgaagg aaatccgctt gaagtggtga ctttccctgt tcgtgtcatg aaagctcttg
    15181 gatgtgaagg cgttcttgtc acaaatgcag ctggtggtat cggctacggc ccaggtacct
    15241 tgatggcaat cacagaccat atcaatatga ccggaaataa cccactaatc ggtgaaaact
    15301 tggacgagtt tggtccacgc ttccctgata tgtctgatgc ctatactaag gtttatcgca
    15361 ataaggcaca tgaagtggct gaaaaaatga acatcaagct agaagatggt gtttatatgg
    15421 gcttaactgg tccaacttat gaaacaccag cagaaatccg tgctttcaaa gtattaggag
    15481 cagatgctgt tggcatgtca actgtaccag aagttattgt ggctgctcat tctggactta
    15541 aagtacttgg tatttcagct attacaaact ttgcagctgg ttttcaatca gaattgaacc
    15601 atgaagaagt tgtggaagtg acccaacata tcaaagaaga tttcaaaggt cttgttaaag
    15661 ctattttatc ggagttgtag gacgaacaaa atcaactgga gcattattac aggaatgtta
    15721 ttttatgtcg tcagtttggc acatctgttc gcaataaaaa aatcaaaaaa taatcacgga
    15781 gtgtgagttc catgaatgtt gaactcagat tctagctttt ctaactaaca taaccaacga
    15841 agggaaagag acgtattcgg tttaaattga gtatggactc gaacatttct tcgtattaat
    15901 ttttaaataa taaaggaaag agagttagtc ctttcttatt tgaactcgat ttttagctct
    15961 cttctattca atatcaatta tgaaaggaat ggggttgtat tcaattgaat acgggcggaa
    16021 agctcggaaa ctagataaac taacttttga gctcacacat ggcgttagtt ccctaaattt
    16081 cagtcgcttt ctgtccgccc tctgaccttc tacaaaataa aaggaaaggt agggctaact
    16141 gtattcattg aattgaatac gggcggagaa ctgtttttct tccttataaa aaataaaaaa
    16201 ataagaaagg tgagggctga gttcattaat ttgaattcgg gctaaggact tggtcaaaaa
    16261 gataagttgt ctagaaaatc aggattttct gccaacttcc tattttgcca tcgttctttt
    16321 aacgccctca gtatcataat ttatgtctat ccatatttct gccaaaaaag gcgatattgc
    16381 tgataaaatt cttctacctg gagacccttt gcgcgcgaaa tttatcgctg aaaatttcct
    16441 agaagatgca gtgtgtttta acgaagtgcg taacatgttt ggctacacag gaacttacaa
    16501 agggcaccgc gtttctgtca tgggaactgg tatgggaatg ccttcgatct ctatctatgc
    16561 tcgtgaatta atcgttgatt acggtgtcaa aacattgatc cgtgttggta ctgcgggtgc
    16621 gattgaccca gaagttcatg tgcgtgaatt ggtgcttgcc caagcagcag caaccaactc
    16681 aaatattatc cgtaatgact tcccagaatt tgatttccca caaattgctg attttggttt
    16741 acttgacaag gcttaccata tcgccagaga aatgggagta acaactcacg ttgggaatgt
    16801 gctttcttct gatgtctttt acactaacat gcctgagcgt aatatggctc ttggtaaatt
    16861 gggtgttaaa gccatcgaaa tggaagcagc agctctttac tatttagctg ctcagcacca
    16921 tgtcaaagcc cttggaatca tgacgatctc agataacttg aatgatccaa ccgaagatac
    16981 tacagctgaa gagcgtcaaa ccactttcac tgatatgatg aaaattggtt tggaaacttt
    17041 aattgccaat gactaataat caaacgctag acatcctttt ggatgtctat gcttataatc
    17101 acgcctttag aattgctaaa gccttgccaa atatccctaa aactgttctc tatttactag
    17161 agatgttaaa agagcgcaga gaattgaacc ttgcctttct ggtggaacat gcagcagaga
    17221 atcggaccat tgaagaccag taccactgtt cattatggct taaccaatcg cttgaagatg
    17281 agcagattgc caattacatt ttggatttag aagttaaagt aaaaaacggt gctattattg
    17341 atttcgtcag gtcagtgtcg cctattcttt accgactttt tctcagacta atcacgtcag
    17401 aaattccaaa cttcaaggct tatatttttg atacaaagaa tgaccaatat gatacctggc
    17461 attttcaggc catgttggaa tctgatcacg aggtttttaa ggcttacctg tctcaaaagc
    17521 agtctcgcaa tgtgacgacc aaaagcttag cagacatgtt gacgttgacc tccttacctc
    17581 aggaaatcaa ggacttggtt tttttgttac gacattttga aaaggctgtt cgtaatcctc
    17641 tggctcattt gattaagcct tttgatgaag aggaattgca tcgcaccact catttttctt
    17701 ctcaggcttt tttggaaaac attatcacct tggcaacttt ttctggtgta atctaccgac
    17761 gtgagccttt ttactttgat gacatgaatg ccattattaa aaaggagttg agcctttgga
    17821 gacaatctat tgtctgatat ttatcaaaaa acacgataac ttgaccgata caggtcttac
    17881 taccgtgttt ttttagtatg acgattgaaa aagaaattaa tcaaaggtta cttcttcgag
    17941 aaggtattcg ataaaacgtt cccccatttt ggacaagttg gctttttcat gcttgataaa
    18001 aacaatgtca atttcgtcag ggacatctag cgggatagcc acaatctggt caccatttag
    18061 attgctattt agaataccac tggcaacggt gtagccatct aaaccaatca ttaagttaaa
    18121 gagggtggca cggtcactga ccacaattga tttgttgtgg ggcatctggg acatcatctc
    18181 ttctgaaaaa taaaaggagt tgtgaatccc ttggtcatag ctcaggtaag gaaaatctct
    18241 caagtcgtcc atgcttaata ggcttttagt cgctagagga tttgatttgc tgacaaaaat
    18301 atgaggctgt gccttaaata atggagaggc agtcaaatga ttgtcatcaa ataatttggt
    18361 caagacatct cggttatagt cgttgataaa gagaacacca atttcagatc gaaagttttt
    18421 gacatcatca atgatttccc aagttcttgt ctcgcgcaaa aagagttcgt accgagtcat
    18481 gtcggtccgc ttgaggagtg agacaaatgc attgactacg aaggcataat gttgagatga
    18541 aacgctaaag agctctcggc cagtattgtg gtttttatag cggtcttcta acagtgatgt
    18601 ttgctctata atttggcgag cataagataa aaattccacc ccatcttttg tcaaggtgat
    18661 ccctttagga tttcggttga aaatggtaat gcccatctcc atttccaaat ccttgaccgc
    18721 attggataga cttggttgtg tgataaataa ttgcttagca gcttcattca tagagccgca
    18781 ctcaacaatt ttgataatat aatgcagttg ttgaattctc ataagtacag tctagctcaa
    18841 aaaaaataaa gacgcaagca caaacgtcat catgggttta gaactttgaa aaagcgctgg
    18901 agtcttttct caatatggcc taggataaat atgattcaat tttgagagtt gaatctatca
    18961 atttcattgc ccttttattt ttcttgtgtt atattaatag tattaacaaa taggtatttt
    19021 tctaatcaaa gggtggtggt cgtgtgaatg ttactgaaca aaatagtcat caaatcttaa
    19081 tccaaaagtt attggtcagt atccactatt tgactctttt tcgagatgaa ctgaagcttg
    19141 tagaacgaac tccttctata cttggagggg aatttccagc tcatttagta cagtctgagt
    19201 tgggagatat tgttgcggcc attgatacct tggatatgca gcaacgcttg attgagtcta
    19261 ccttttggta tgaagaatca gcttttaagt tgatgaacaa aactttggat attgtcgata
    19321 attggattaa aggagtggat catctgatag atttatgcca gtccaaagaa gtctttcaaa
    19381 ttattattgg agataaacgc attcgagttt ttggggtctt aagtgatgtt ttttcatctt
    19441 taaaagtgag tgctttgtca cttaaggaag ctcctattcc ggatgtgctc tatgaacata
    19501 tctagagggt taatcttgaa gaagaagctt ttataaaata ttaccaaagc cctaaggtac
    19561 ccacaggtga gtttgaataa atgattgggt aaaaattata aaatgagttg acgtaagtat
    19621 acaaaaaaag ttatagtagg aaagatgtgt tcaaataaca aaaagttttg acatcttgtt
    19681 ttaaaaaagc tataatagtt taaatttaga cacctttaag tgagtccaga gaggcaaaca
    19741 aggtatacaa gataaaaaaa gggaattccc ttttagtttg ctgtagcctc gcttctttgg
    19801 tagcgaggct ttttggtgct taatgagata ttgacacatt atagaaagga taagttatga
    19861 aagaagaacg cccaattatt gctttagact tttcatcatt tgaggagact aaagcatttt
    19921 tagacttatt tccagcagaa gaaaagctat acgtgaaaat tggtatggaa ttatattatg
    19981 cgcaaggacc agatattgtt cggtatatca aatcgttagg gcataatgta tttttggatt
    20041 taaaattaca tgatattcca aatactgttc gtgctgctat ggcagttctt aaagaattag
    20101 atattgatat ggcaactgtt catgcagctg gtggtgtaga gatgctaaaa gcagctcgag
    20161 aaggactagg tcaaggccct accttaattg cggtaacgca gctaacttca accagtgaag
    20221 accaaatgcg tggtgatcaa aatattcaaa cgagtctttt agagtctgtt ttgcattaca
    20281 gcaagggggc agctaaagct cagctagatg gggtggtttg ttcggcacaa gaagtagaag
    20341 ctatcaaggc ggtgacacct acgggattta cttgcttaac tcctggcatt cgtcctaaag
    20401 gcagtaatat tggcgatcaa aaacgagtga tgactccaaa ccaagcaaga cgcattggaa
    20461 gtgattatat tgtggtaggg cgaccaatta cccaggcaaa agacccagtg gctgcttacc
    20521 aagccataaa agctgagtgg gcaggctaac agataagatt aggaaaccaa cacttgtctg
    20581 ttaaagaaga aaaaggagaa taagaaatga cactagcaag ccaaattgca actcaattac
    20641 ttgatattaa agctgtttat ttaaagcctg aagatccttt tacgtgggca tctggcatta
    20701 aatcacctat ttacactgat aatcgtgtca ccctttctta tcctaagact cgtgatttaa
    20761 ttgagaatgg gtttgtggaa actatcaggg ctcatttccc agaagttgag gtcatcgctg
    20821 gtacagctac agcaggtatt cctcacggtg ccattatagc agataaaatg actcttcctt
    20881 ttgcttatat tcgcagtaag ccaaaagatc atggagcagg caaccagatt gaggggcgtg
    20941 tgcttaaagg ccaaaaaatg gttatcattg aagatttgat ttcaacaggt ggttcggtac
    21001 tagatgcagc cgcagcagcc agtcgtgagg gagctgacgt tctgggagtt gttgcgattt
    21061 tcacttatga gttaccaaaa gctagtcaga attttaaaga agctggtatc aagttgatta
    21121 cgctttctaa ttatactgag ctaattgcag ttgcaaagtt gcaaggctat attactaatg
    21181 atggtttaca tttacttaaa aaatttaaag aagaccaggt aaactggcaa caataaggaa
    21241 ctatcagcca ggtttatttt taatgaaaaa atctctttaa ccccaattca aaatgttatg
    21301 ttttgattgt tttgtctaca ttccttacac atcacattct aatttctaac cttttaatgg
    21361 tggttttctt ttatttgtgt tttaataaaa aagaatgttt taggattcat atcttagaaa
    21421 ggaagagtag ctatgactta tcaagatgcg acggctatgg ctattgctgt tcagactggt
    21481 cagaccacac cactagaatt agtaacccag gctatttata aggctaaaaa gttgaatcct
    21541 accttaaatg ctattacctc agaacgcttt gaagcagccc tagaagaagc caaacaaagg
    21601 gattcttcag gtctgccttt tgcaggagtt cccatttttt tgaaagattt gggacaagaa
    21661 ttaaaaggtc actcatcaac ctcaggttcc agattgttta aagagtatca agcggctaaa
    21721 acggatttat ttgtgaaaag attagaagct ttaggcttta ttattttagg gcgctccaac
    21781 acgcctgaat ttggctttaa aaatattagc gatagcagtt tgcacggacc agtgaattta
    21841 ccaaaggata atacacgaaa tgctggtggc tcgtcaggtg gtgcggcagc tctagtgtca
    21901 tcaggaatta gtgcactagc accagctagt gatggaggtg gttctattcg aattccagcc
    21961 tcgtttaatg gcttaattgg gctcaaacct agccgtgggc gcatgcctgt cggacctggt
    22021 tcttatcgaa gctggcaagg agcctcagtt cattttgcct tgaccaaatc cgttagagat
    22081 actagaaatc tactctacta tttacagatg gaacaaatgg aaagcccctt ccccttagcc
    22141 accttaacaa aagatagtat ttatccatcg ctacaacgtc ccttgacaat tgctttttat
    22201 caacggttaa gtgacggtag cccagtatct ttagatactg caaaagcttt aaaacaagca
    22261 gtaacttggc taagagaaca agggcatcag ctagttgaat tggaagagtt tcctgtaaat
    22321 atgacagaag tgattcgtca ttattatatt atgaatagtg tggaaacggc tgctatgttt
    22381 gctgatattg aagacacttt aggacgtccg atgaccaaag acgatatgga aaccatgacc
    22441 tgggctattt accaatcagg taaagacatc ccagcttggc gttactcaca ggtccttcaa
    22501 aaatgggata cgtacagtgc aaccatggct agttttcatg agacttatga cctgttgttg
    22561 acgttcacaa ccaacacacc agctcctaag cacggagaac ttgtcccaga ttcgaaactc
    22621 atggctaact tggctcaagc tgaaattttc agcagtgaag aacaattcaa tttggtcgaa
    22681 accatgtttg gtaaaagtct ggctattaat ccttacacag ctctgcctaa tctaactggc
    22741 cagccagcta ttagtttacc tacttacgaa actaaggaag gtctcccaat gggcattcaa
    22801 ctaattgcag ccaaaggtag agaggaccta ttattaggaa ttgcagagca gtttgaggca
    22861 gcaggattat tgaagattcc tcaataataa tcttataaaa cagtttaact attatagatt
    22921 aactttttaa agagattgag cgctcactga taacacaact taatcaaaat gttatactat
    22981 tcttatctta ataaaggagt tactatgaag aaatcagtta ctttactgtc tatcggactt
    23041 gccagccttt tattggcagc atgtgcgcca cataaatctc aaaaatcaag ttggaacact
    23101 atcaaagaaa aaggggtgtt aaaagtagct accccaggaa cctatcagcc aacttctttt
    23161 tacaacgata ataatgagtt agtaggttac gaagtagata tggtcaaaga aatcggtaaa
    23221 cgacttaaca ttaaagtcaa gtttgttgaa acaggatttg accaagcctt tacctcagtt
    23281 gatagtggtc gagtggatat ttctttgaac aactttgaca ttaccccaaa acgtcagaaa
    23341 aaatacaata tctctacgcc ttataaatac ggggtgggag gcatgattgt ccgtgctgat
    23401 ggcagctcaa acatggctaa aaaagatctt agcgactgga aaggaaaaaa agcagccggc
    23461 gcttctggaa cagagtacat gaaagtagcg caaaaacagg gagctgaact ggtgacctac
    23521 gataatgtta caggagatgt ttatctaaac gatgtggcta acggtcgaac agatttcatt
    23581 ccaaatgatt acccagctca aaaattattt gtggattaca tgttatctca aaatccaaat
    23641 ctaaatgtca aaatgagcga tgttcagtac aacccaaccg aacaaggaat tgttatgaac
    23701 aaaaaagacg atagcctcaa gaaaaaaata gatgctgtta ttaaagacat gataaaagat
    23761 ggtagcttga agaaaatctc tgaaacctac tatgctggtc aagatttgac aaaacctttt
    23821 ggtaaagaca agaaaattcc cgtcattgat acgaaagacg ttaactaatg cttgatgtta
    23881 aaggagtcct aaagacatga ttaatatccc attaatgaaa gatagtttag gatttgtgtt
    23941 atcgggatta ccttataccc ttggtatttc gttgctcagt ttttttacgg gtctattttt
    24001 aggtttaggc ctagcccttc tgggaaggtc acgtcagccg ttgattcatt accttgttag
    24061 agcgtacatc tctattatgc gaggtgtgcc gatgattgtg gtgctctttg ttctttattt
    24121 cgggttgcct tattatggtt tagaattacc agccttactt tgcgcttacc ttggtttttc
    24181 tatggtcagc gctgcctaca tttctgaagt ttttcgctct tctatagaag ctattgacaa
    24241 gggacagtgg gaagcagcta aggctttggg gttaccatat tctcttatgg ttaagaaaat
    24301 tattcttcct caagcctttc gaattgcagt tcctcctcta ggcaatgtca ttattgatat
    24361 ggttaaaagt tcgtcgctag ctgccatgat taccgtacca gatatttttc aaaatgccaa
    24421 aattatcggt ggtagagagt gggattacat gtccatgtat attttagtgg cctttattta
    24481 ttggcttatt gcttttttgt tagaacgtta ccaagaattc ttagaaaata agctagcact
    24541 tgtttaatat cctgtaaaaa acgaatatta accctggaaa tatcatattt tcagggtctt
    24601 tctatttaaa atgtggtaaa ctagatagaa aaggacatcg tatttaactt agaaactgac
    24661 gtgattagaa aggaatctta tggctcattc aatttggcat gagaaaatca aatcattttt
    24721 gccggagcat tactatggtc gcatcaatca ctttttagat gaagcctatg cttccggtct
    24781 tgtctacccc caacgagaaa atgtctttaa agccttacaa gtgactcctt tggaagaaac
    24841 caaagtgttg attttaggac aagaccctta tcatggcccc aaacaggccc agggcttatc
    24901 attttcagtt ccagaagaga tttctgctcc gccatccctt attaatattt taaaagaatt
    24961 agcagatgac attggtcctc gtgaccatca tgatttaagc acttgggcta gtcaaggggt
    25021 tctgcttttg aatgcttgct taacagtgcc agcaggccag gctaatgggc atgcaggctt
    25081 aatatgggag ccatttacag acgctgttat taaagtgctg aatgagaaag acagccctgt
    25141 agttttcatt ttgtggggag cttatgcaag gaagaaaaaa gccttcatta ctaatccaaa
    25201 gcaccacatc atcgagagcc ctcatccaag ccctttgtca tcttatcgtg gcttttttgg
    25261 cagcaaaccc ttttcaagaa ccaacgctat gttagaaaaa gagggcatga ttggcattga
    25321 ttggttgcaa taggaagaag tattagtgat tatcagacag atggtttgag gtaaactgcc
    25381 tatgggtaaa gtttcagtat tattggcaga caggtctgtc tattagtttt tttgtgacag
    25441 aggattaaag tcttgtgagt aaaacagata agtgagaaga aggagaaaac atgatactca
    25501 tcaaaaatgg acgcgttatg gacccgaaat cgcagagaga tcaagtggca gatgtcttga
    25561 ttgatggtaa acagattgta aagatagctt cagctattga atgccaagaa gctcaagtga
    25621 ttgatgctag tggtcttatt gttgctccgg gtttggtcga tattcatgtg cattttagag
    25681 aacccggtca aacgcacaaa gaagatattc acacgggagc cttggcagca gcagcaggtg
    25741 gtgtgactac ggttgtcatg atggctaata ccaatcctgt catttcagat gtcgaaactt
    25801 tacaggaagt gctagctagc gcagctaaag aaaagattca tatttacacc aatgccagtg
    25861 tcacccaagc ctttaatgga aaagacgtga ctgattttaa agctttgttg gaagcaggag
    25921 cagtaagctt ttcagatgat ggtattccct tagaaagttc taaagtttta aaagaagcct
    25981 ttgatttggc taatgccaac caaactttca tttctttgca tgaggaagat cctcagttaa
    26041 atggggttct tggttttaat gaaggtattg ctgaggagca ttttcatttt tgtggggcaa
    26101 ctggtgtagc agaatatagt atgattgcaa gagatgtcat gattgcttat gacaggcaag
    26161 ctcatgttca tatccaacat ttatctaaag cagaatcggt tcaagtagtg gcttttgctc
    26221 agcagttggg tgctaaggta actgctgaag tgtccccaca acatttttca acaactgaag
    26281 atctcttatt gaccgcaggt accagcgcca agatgaatcc tccccttcgt acacaaagag
    26341 atcgcttagc tgtcatagaa ggcttgaaat cgggtgttat cacagtcatt gccactgatc
    26401 atgctcctca tcacaaggat gaaaaagctg ttgatgatat gactaaagct ccatctggta
    26461 tgacaggact tgaaacttct ttgtcattag gtttgacgca tttggttgaa ccaggtcatc
    26521 ttacacttat gtcactatta gaaaaaatga cgcttaatcc agctttgctt tatggttttg
    26581 atgcgggtta tttggcagaa aatggtccag cagatttggt tatttttgca gacaagcaag
    26641 aacgtctgat cactgagaat tttgcttcta aagctagtaa ttccccattt attggtaaca
    26701 aactcaaagg tgtcgtgaaa tacactattg cagacggaga ggttgtttac cctaattaac
    26761 aaatgagtta aaacaaaaaa gcctgacttt cagagaaagt caggctttta gtaaatttat
    26821 tttttaggca cttgtttgct taaatttagc ccccaaggta ttagattttc agtatgatgt
    26881 ttgatacgac taatgttatc tttgtgtctt ataataataa tgaacgcaag taatatcaca
    26941 ataaaagtta aaaagtagtc ataatttggt aaaagaaaat gaatggcagg aaatgttaaa
    27001 acagataaca caccaacgat agctgaaacc acactagcta aagatatcat actaaataaa
    27061 tagagaacta aaacaaagat agatgctaaa aaaaagagat ataacggagc aaagcctagc
    27121 aatacaccag cacttgttgc tacggcctta ccacctttaa agttggcaaa aataggaaaa
    27181 gtatgcccta aaactgcgaa aaagccgata gcaatggatg aaattgaagt cataccaaaa
    27241 ataattggta acaatattga aagtgtccct ttaaacatat caatagctaa ggtagctgtt
    27301 cctgccttga cacctaaaat ccgaaaagta tttgtggttc cagtatttcc tgatccatgc
    27361 tctcgtaagt tgatgtggta aaagtactgt ccaatccata gtccagttgg aatagaacca
    27421 agtaaatagg caatggtaat aaaaagtagt aatttcataa tccttattat aacatattca
    27481 tagattggag aactagatct ggaaaagaat tcggaaaaaa ttagcaaatt attttgcaaa
    27541 attggtaaaa aacttgtaag ataaaaaaga tgaaactgtc tggaggtcgg tgttgactaa
    27601 gaaagaaatt acaattaata attataatga cgatgctatc caagtcctag aagggttaga
    27661 tgctgttcgc aagcgtccag ggatgtatat cggttcaaca gatgctacgg gattgcacca
    27721 cctgatttgg gaaattgttg ataatgctgt cgatgaggcc ttgtctggtt ttggagatga
    27781 tattaaggtt gttatcaata aagatggctc ggtcagtgtg gcagatagcg gacgtggaat
    27841 gccaacaggt cagcatgcca tggggattcc caccgttcaa gttattttta cgattcttca
    27901 tgcaggtggt aaatttgg
//
LOCUS       DAXMQE010000022        26281 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.022, whole genome shotgun sequence.
ACCESSION   DAXMQE010000022 DAXMQE010000000
VERSION     DAXMQE010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 26281)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26281)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26281
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.022"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            complement(<1..2509)
                     /locus_tag="ACF4ZO_001162"
     CDS             complement(<1..2509)
                     /locus_tag="ACF4ZO_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2 TIM barrel-domain
                     containing protein"
                     /protein_id="HFD5486712.1"
                     /translation="MTPDSKEQTVTGYQYHYIDQEGRKQPFNQGWRFLMADVACAQAP
                     SFDDSNWQVIHLPHDFSLTQPYTRNGEAESAYKLGGVGWYRHYLVLDEVLAGCHVAIT
                     FEGSYMETEIYVNGQFIGKHLNGYQEFTYDISDVVTFGAENLLAVRVENKVPSSRWYS
                     GSGLYREVSLSVLPQLHFVADQVAMTLADTAVQEKGQQKVDLRFALNQSIQTCHYQLS
                     LCLWEQSHCSKDKKLLYQETEVPLADLAFQRQYGLTLSLEELQLWSPDNPHLYDLELT
                     LYYQGQVIDCFSLETGFRQLTFTANQGLFVNGRAVKLKGVCLHHDQGGLGACAYEDAL
                     ARQLVLLKDMGANTIRSTHNPSSPKLRQLANRLGFFVIEEAFDTWTYAKNGNVNDFSK
                     YFHQTIGTENANYLQRVRSPETSWAQYSIEAMVWSAKNDPSVLMWSIGNELMEGFSAD
                     VSHYPELTRQMCQWIAAIDTSRPITFGDNKLKEADFCWHEEVSQMATLLSQLDHPQGL
                     IGLNYANGKDYDKLHEEHSDWLLYGSETASAITSRAYYKETKKVLDSGYHLTSYDHAK
                     VDWGAFASQAWYDTITRDFVAGECVWTGFDYLGEPTPWNKIDSGVVGLWPSPKNAYFG
                     ILDTAGFPKDSYYFYQSQWAQGQTTLHLLPVWQKDQLCFDEQGLVEVVVYSNAASVQL
                     MFEDEQGNVTDYGRKAFHTYSTPTGHTYQLYQGADAAKNPHENLYLTWRVPYQKGLLR
                     AVAYDISGKSIPKTSGRSQVRTYGSVAKLSWKAFEAPIDAPWELLYLDLSLLDSRGEL
                     VSHAQDWLQVQVEGPARLLALDSGNPTDHTPYQEPLRQ"
     gene            complement(2529..4013)
                     /locus_tag="ACF4ZO_001163"
     CDS             complement(2529..4013)
                     /locus_tag="ACF4ZO_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFD5486713.1"
                     /translation="MYKVLLVDDEYMILQGLTMIIDWQALGFEVVQTARSGKEALAYL
                     TQYPVDVMISDVTMPGMTGLDLIEAAKTYHPQLQTLILSGYQEFSYVQKAMELETKGY
                     LLKPVDKAELQAKMKQFKDWLDAQQAESIRQEAYHDSLLTLWLTDELSEKEFQQLSQG
                     LPAAALTGFTALYLDCQEWQAAIDAYFEREGQPFYLKKEEDKKVYLAVLLGKTDQAKA
                     FTYDLQKRFSRNMHQLILGETVDDWENVYESYNQVLKSLFYNCEVSPIRAKDKSKIEL
                     PESRLQFFAFNKALMIGDEPTILSKLEAIFDEMKTLNFSPEDVKHVSFLLFSDIYRQF
                     PILDKMTYLSMVKTIHDSQSIDRILRELKKVLDVTNQNNSPEKRYSDLVSETIDCIRK
                     EYHQELTLKAIADRLHVNGVYLGQCFKNETERSFTQYLNHVRIQKAQQLLLYTNQSIN
                     EIAYETGYNTNHYFIKMFKKLNGLSPKEFRDRYKDNYQAIKGDQ"
     gene            complement(4013..5737)
                     /locus_tag="ACF4ZO_001164"
     CDS             complement(4013..5737)
                     /locus_tag="ACF4ZO_001164"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFD5486714.1"
                     /translation="MSVKTLGRYVTNHFKQGFLINRLMKLYSLLIVSFFTLAAIGLSS
                     YSISSTYKRVDAEAQMRLEETLGRLQSQNDITLRVLDQLVGRSEDYHNLYQYMTLTPN
                     QYFSNVFEDWEKGKDTVLFSEEVRRLFDLYPDVTSMTLLLEDSSAYLYADKVIKTGRL
                     LYSKPEKVTGNVLVRSIRNPESGDVTGRLYLTFDKPPTLVETQQDHYLATFAFDYYGR
                     KLFHQGGRRFPHLEAEVKKAIKADRAADLSNLSKAYRMQYNRSGDLLAYVAVRKSYLL
                     AEAVRTVFVYGLVSLLLAWLLLQLLFRVFRNYIQQVSEITDTVEMVAAGDLSLTIDNS
                     HMELELYHISEAINQMLASIKAYIDEVYVLEVEQRDAQMRALQSQINPHFLYNTLEYI
                     RMYALSCQQEELADVIYAFASLLRNNISQDKMTTLKEELAFCEKYIYLYQMRYPDSFA
                     YHVKIDESIADLAIPKFVIQPLVENYFVHGIDYSRHDNALSIKALDETDHLLIQVLDN
                     GRGISQERLADMKRRLQEHQTTGNSSIGLQNVYLRLFHHFRDRVSWSMAKEPNDGFII
                     QIRIRKDA"
     gene            complement(5727..6332)
                     /locus_tag="ACF4ZO_001165"
     CDS             complement(5727..6332)
                     /locus_tag="ACF4ZO_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HFD5486715.1"
                     /translation="MNGIEKTCFLIWKMIQLTLIFHLLSLAGLIVFGVGPAWQTIVTL
                     FLKTPQEENHYSLKRAVQLWKSYFKEANLRFGLFALTFLFLTFNLHWAVQFPSLFWFT
                     VSFLIVIAMVWLTMTYLYMVFYAVSYEINLWNNMKLAFISVFLSFKSFLLMLSVLLGI
                     TLVTWQYKGLYLFLTFGALVFCLDFVTKANRRLVDGVIDEC"
     gene            complement(6638..8083)
                     /locus_tag="ACF4ZO_001166"
     CDS             complement(6638..8083)
                     /locus_tag="ACF4ZO_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFD5486716.1"
                     /translation="MKKWQKIVCVTGTVLAASSLAACESKSASKDSDVKLLMYQVGDK
                     PDNFDELMTIANKRIKEKTGATVDLQYIGWGDWDDKMSTIIASGENYDIAFANNYVVN
                     AQKGTFADLTTLMPKYAKKTYKNLDPAYIKGNTIDGKLYAFPVDANVYAQQVLSFNKE
                     LVDKYGLDISNIKSYADAENVLKQFHEKEPNTAAFAIGQVFSMSGDYDYPLTKNQPFA
                     VKIDEGKPTIINQYEDESFKNNLRLMHKWYKEGLIPTDAATNTEGYPLEGNTWFMREE
                     TQGPMDYGDTILTNAAGKDIVSRPLTKPLKTTSQAQMANFVVSSVSKNKEKAVEVLSL
                     LNSDPELLNGLVYGVEGKAWEKIGDKKIKLLDGYQPKMHMGAWNTGNNKILYTQESVT
                     DDMIAKRDQSIKDAKESPILGFTVDTKVIKTELSNISNVMNRYKASINTGTVDPDEAL
                     PKLLADLKGAGWDKVQKEVQKQLDDFVAKDK"
     gene            complement(8164..9090)
                     /locus_tag="ACF4ZO_001167"
     CDS             complement(8164..9090)
                     /locus_tag="ACF4ZO_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFD5486717.1"
                     /translation="MEKKKKVEKVNVRTFDRKTNAIFNILIGLFAISCIIPFIFVIII
                     SFTDESYLINHGYSFFPDVWSTKAYQYIFQGAMSHRIMRSFGISVFITVVGTFINTTM
                     TSTYAYAISRPYFPYRRFFTVYALITMLFAPGMVANYLVVSNLLHLKDTVWALILPMA
                     LGPFGILVMRTFFKKTVPDSIIESARMDGASEWMIFMKIVLPLAVPGIATISLFSALT
                     YWNDWFNALLYVQSENLYPMQYLLMKIQSNLQALAQNAGMSAQMADSLASLPKESVRM
                     AIVVIATLPIALTYPFFQKYFVGGLTIGGVKE"
     gene            complement(9100..10050)
                     /locus_tag="ACF4ZO_001168"
     CDS             complement(9100..10050)
                     /locus_tag="ACF4ZO_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004219264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD5486718.1"
                     /translation="MTRQTNKKTSFWKNVIKYRALLLMVLPGFIWFIFFFYIPVLANV
                     VAFKDFHYSAGGFMESLKESPWVGLANFKYLFASKDAWLITRNTIAYNVIFLLFNVFF
                     AIAFAIIMSELRNKRTVKVYHTMSLLPYFLSWVVIEYFVSAFLNTDKGFINQLLTGSG
                     GAPIKWYSNPTWWPLILLFMSVWKGLGYNSIIYYASVKGISDTYYEAAMVDGASKWQQ
                     IRNITIPQLLPMMSILLIINIGNIFKSDFGLFYVIPKNSGPLYDVTSVLDTYVYNALT
                     ATGDIGMASAASLYQSVVGTSILLVTNAIVRRMDPDAALF"
     gene            10267..11145
                     /locus_tag="ACF4ZO_001169"
     CDS             10267..11145
                     /locus_tag="ACF4ZO_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HFD5486719.1"
                     /translation="MSLLCLDIGGTSLKFALCHNGQLSQQSSFPTPSSLEKFYQLLDQ
                     EVARYSAYHFSGIAVSAPGAVNKEKGIIEGASAIPYIHHFKIQEALEERLHYPISIEN
                     DANCAALAEATLGAGKGASSLAMLVLGTGVGGSLVIDGKIYHGAHLFGGEFGFMIMND
                     RYQTFSQLGTVVNMAKRYSAIVNNGKDYTGKAVLALAEQGDPLALKERRVFLQSLAIG
                     IFNIQHAFDPQLILIGGGVSQADFLLSAIEAELDKLYQAVEISDLRPQLAICHFKNEA
                     NLLGAAIDFYQEHKEA"
     gene            11288..11410
                     /locus_tag="ACF4ZO_001170"
     CDS             11288..11410
                     /locus_tag="ACF4ZO_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486720.1"
                     /translation="MPGPFVDVVVADASVKGIGHQLMLELLEAMLVIANKQSLT"
     gene            complement(11756..13198)
                     /locus_tag="ACF4ZO_001171"
     CDS             complement(11756..13198)
                     /locus_tag="ACF4ZO_001171"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFD5486721.1"
                     /translation="MLAFPKEFWWGGATSGPQSEGRFAKQHRNLFDYWYEEEPDLFYD
                     YVGPDTASDAYHQIESDLALLASLGHNSYRTSIQWTRLIDDFEQVTINPDGLAYYNRV
                     IDACLANGIRPVINLHHFDLPIALYQAYGGWESKHVVDLFVAFSKVCFQEFGDRVKAW
                     FVHNEPMVVVEGSYLMQFHYPAIVDGKKAVQVAYNLALATAKVIQAYRRGPAKLSNGR
                     IGTILNLTPAYPASQSETDMAAAHFAELWNNDLFMEAAVHGKFPEELVAVLKKDGVLW
                     QSTPEELALIAENRVDYLGLNFYHPKRVKAPDAIPVISPSWSPEWYYDAYLMPGRRMN
                     VDKGWEIYPEAVYDIAIKMRDHYDNIPWFLSENGVGISGEDRYRDETGQIQDDYRIQF
                     LKEHLTYLHKGIEAGSNCFGYHVWTPIDGWSWLNAYKNRYGLVENNIHTQVRRPKASA
                     YWFKKVATHNRLISLEVMEEFGGSASHLSD"
     gene            complement(13224..14918)
                     /locus_tag="ACF4ZO_001172"
     CDS             complement(13224..14918)
                     /locus_tag="ACF4ZO_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylglucosaminidase"
                     /protein_id="HFD5486722.1"
                     /translation="MTIYHALKDYQEVMTRGDYLVLDMLLTCRFVGRFFRFENQKALL
                     AELATSKYFQWIEEGQAEVTMKHFFNRQLAKDAFTLKVSEDKEIIIESQNLRGFRYAQ
                     EALLKVMTFKGDKLYLPIVSVKHSPSFAMRGIIEGFYGTPWTREERLDCLRFIGRKRM
                     NTYMYAPKDDDYQRKQWRDLYPEDWVTYFKELLAVAKEQGIDFWYMISPGLDFDYTKE
                     ADYQLLYQKLQQLLALGVCHFGLLLDDIDYQIVDAVERRFKKTAYAQAHLATEVHHFL
                     NQQHAAPELVICPTEYDNHHDSIYLQELSERIPKEVAFFWTGPSTLASQISQADIETM
                     AAVYQRPIIIWDNIPVNDYQKDPERLFLTPFANRSPFLCQPDYQVKGIVSNPMISWEL
                     SQLTLTDMSHYLWDANRYQPSHSWLETLTDYTGDAELALALQAFAWHNGNRHLHRDLP
                     FEVEEALLAKDVSTLSAWVDELVERVNTLRKLDKPAFQQAIAPWFERVAKDQDFWQAM
                     LNQEPQLETLYADLQEDKHRIGSDIPSRYYRIYYQQQDKLTANQGQVTQARPEDYA"
     gene            complement(14969..16009)
                     /locus_tag="ACF4ZO_001173"
     CDS             complement(14969..16009)
                     /locus_tag="ACF4ZO_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFD5486723.1"
                     /translation="MTKLLYKKIYHFIKEQIASGRLQIGDRLPTEKELSEQFSVSRIT
                     SKRALVELEQEGLITRSRGKGSFVAKKQVTSPEANKDLLLILPFASDYELGDYAKGIM
                     TSIAETGYRLMVQLASTVRLDTLSDYAGIIYYPEDVNHSIDFLFYCDHHHIPLVLLDK
                     SLDLFQFPSVVADNKGGVYQLTQHLIEQGCDQISFVATGSFGEVSSVRDRYLGYLAAM
                     AETSLPSWYFPKEKAETSDAYLNRLVKTLSETTATKRGLVVENDWLAIQLIQKITQVG
                     LSIPDQVAIVGFDNSQASRLLSPKLSTAAQDFYQMGQEAAKVLLQIIHEPDQAVVSCQ
                     LPVQVFIRESSH"
     gene            16142..17428
                     /locus_tag="ACF4ZO_001174"
     CDS             16142..17428
                     /locus_tag="ACF4ZO_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HFD5486724.1"
                     /translation="MTRPIPTSVSQFMAKVESLCGDQHPDWALNFKTSFANTLETTLK
                     TYEDGTSFLLTGDIPAMWLRDSTAQMKPYLFLAKEDEEIRKIIAGLVKRQFRYICIDP
                     YANAFNEEANEKGHQTDHTQMNPWIWERKYEIDSLCYPIQLAYLLYRETGSTDQFNDD
                     FHRGVELILDLWTVEQDHAQSPYLFERDTWRKEDTLTHAGKGSPVAPTGMTWSGFRPS
                     DDACQYGYLIPSNMFAVVVLSYLEDLYNNLFHNESVATRAKQLKEAIQSGIADHALVQ
                     NSKGETIYAYEVDGLGQFSIMDDANIPSLLAAPYLGFCAKDDPIYLATRRTILSQENP
                     YYYQGNAAAGIGSSHTPENYIWHIALALQGLTALDQDSKKEMLDLLVATDAGTHLMHE
                     GFDVNDPYQYTREWFSWANMMFCELLLDYLGFSIAP"
     gene            17443..20148
                     /locus_tag="ACF4ZO_001175"
     CDS             17443..20148
                     /locus_tag="ACF4ZO_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HFD5486725.1"
                     /translation="MATKKVHIISHSHWDREWYMAYEQHHMRLINLIDDLLEVFQTDP
                     DFHSFHLDGQTIILDDYLQVRPEREPEIRQAIASGKLRIGPFYILQDDFLTSSESNVR
                     NMLIGKEGCDKWGASVPLGYFPDTFGNMGQTPQLMLKADLQAAAFGRGIRPTGFNNQV
                     DTSEKYSSQFSEISWQGPDDSHILGLLFANWYSNGNEIPTTEAEARLFWDKKLADAER
                     FASTKHLLMMNGCDHQPVQLDVTKAIALANQLYPDYEFVHSCFEDYLADLADDLPENL
                     STVQGEITSQETDGWYTLANTASARIYLKQANTRVSRQLENITEPLAAMAYEVTSIYP
                     HDQLRYAWKTLMQNHPHDSICGCSVDSVHREMMTRFEKAYEVGHYLAKEAAKQIADAI
                     DTRDFPMDSQPFVLFNTSGHSKTSVAELSLTWKKYHFGQRFPKEVYQEAQEYLARLSQ
                     SFQIIDTSGQVRPEAEILGTSIAFDYDLPKRFFREPYFAIKVRLRLPITLPAMSWKTL
                     ALKLGNETTPSETDSLYDDSNQCLENGFLKVMIQTDGRLTITDKQSGLIYQDLLRFED
                     CGDIGNEYISRQPTHDQPFYADQGVTHISVRNNTIQVAELEIQQTFTIPVSADDRLQA
                     EMEAVIDITERQARRSQEKAELTLTTLIRMEKNNPRLQFTTRFDNQMTNHRLRVLFPT
                     HLKTDHHLADSIFETVKRPNHPDVTFWKNPSNPQHQECFVSLFDGENGVTIGNYGLNE
                     YEILPDTNTIAITLLRSVGEMGDWGYFPTPEAQCLGKHSLSYSFESITKQTQFASYWR
                     AQEGQVPVITTQTNQHEGTLAAEYSYLTGTNDQVALTAFKRRLADNALITRSYNLSND
                     KTCDFSLSLPNYNAKVTNLLEKDSKQSTPSQLGKAEILTLAWKKQ"
     gene            complement(20249..21604)
                     /gene="rocA"
                     /locus_tag="ACF4ZO_001176"
     CDS             complement(20249..21604)
                     /gene="rocA"
                     /locus_tag="ACF4ZO_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator RocA"
                     /protein_id="HFD5486726.1"
                     /translation="MLEDFLQFLGFIFLDIIEIMLTLKLFSFVSAIPLRLKNIFYLSL
                     SMVLFQVVFWAFFPDHFILDVVMLAQFLFFALIALYYGKSIKAKFLMFYAFFPLVSIS
                     LVKRFIVFFVMPLFGMPYSVVKHNTLLIYSITCFSIFLIYRCIQVFHFDFSTWRQYFQ
                     SHRASKLLVFTNSSMALYYLCVQGIDVMSPSLSGLATTTARSIIVLFYFILFLTLLIH
                     LERYVKQNSIEAIVQQKEYRELINYSQHLGLLYQDIQELRQLLTTVSSRLKIGIEQND
                     ISIVRLTYEGILNAEKNNAKDDRLDLTCLDKLQVEAIRHIVLAKLIEAKNKKLKVEVS
                     IPNCIATFFLELVDFTKLLSFLLDNAIEMSLETKQPCLSIAFLDQNHKLVIVIQSSTK
                     QGQNDSQSVFATPALKKRDDWQFDLRNVTTILNRYDYLTISSQIHDGILTQLIEIAKP
                     D"
     gene            complement(22270..23625)
                     /gene="rlmD"
                     /locus_tag="ACF4ZO_001177"
     CDS             complement(22270..23625)
                     /gene="rlmD"
                     /locus_tag="ACF4ZO_001177"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HFD5486727.1"
                     /translation="MVVKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIFC
                     QITAVKRNFAEAKLLMVNKASKNRVKPACSVYETCGGCQIMHLAYPKQLDFKDDVIRQ
                     ALKKFKPTGYEQFEIRPTLGMKKPDHYRAKLQFQLRSFGGTVKAGLFSQGSHRLVPID
                     NCLVQDQLTQDIINKITQLVDKYKLPIYNERKIAGIRTIMVRKAQASDQVQIIVVSSK
                     EVRLARFIGELTKAFPQVKTVALNSNCSKSSEIYGDETEILWGQEAIHEEVLDYGFAL
                     SPRAFYQLNPQQTEVLYGEVVKALDVGSKDHIIDAYCGVGSIGFAFAGKVKSVRGMDI
                     IPEAIEDAQKNAKSMGFDNAYYEAGKAEDIIPKWYKQGYRADAIIVDPPRTGLDDKLL
                     KTILHYQPKQMVYVSCNTSTLARDLVQLTKIYDVHYIQSVDMFPHTARTEAVVKLQKR
                     V"
     gene            complement(23816..23998)
                     /locus_tag="ACF4ZO_001178"
     CDS             complement(23816..23998)
                     /locus_tag="ACF4ZO_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Paratox"
                     /protein_id="HFD5486728.1"
                     /translation="MLTYDEFKQAIDNGYITADTVMIVRKNGQIFDYVLPHEEARNGE
                     VVTEEVVEEVMVELDK"
     gene            24238..25236
                     /gene="sda"
                     /locus_tag="ACF4ZO_001179"
     CDS             24238..25236
                     /gene="sda"
                     /locus_tag="ACF4ZO_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptodornase A"
                     /protein_id="HFD5486729.1"
                     /translation="MSKHWKHLFIRYTFTALATLFLGLFPISKTTNSIIYAETTDISN
                     VWNIVQHPNYYIVEGKSHLNKEKFPQIYHTTEKVYRKSGQSTKRVTVSDIQYSILDGY
                     GRSGEAYGVITKDMIDMSAGYREKWESKPEPSGWYSYFFKNTNQRATESDYKHSPKNV
                     SKISNNIKASIPLSNGRTRHGYLFDRSHLIADSLGGRPFRNNLITGTRTQNVGNNDRK
                     GGMQYIENKVLDHIKKNPKVHVYYKATPVYQGSELLPRVVLVSALSSDRTIDETVRVF
                     NAVAGFNIDYQNGGLLTESPVSEIGNIEDSTTDEIENSVDDSEEIVYNDITTEEVN"
     gene            complement(25377..25937)
                     /locus_tag="ACF4ZO_001180"
     CDS             complement(25377..25937)
                     /locus_tag="ACF4ZO_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019781505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFD5486730.1"
                     /translation="MKYLEKEEIQQLLKSFKGFNDGTSTPHDVEVFLHQKAVEFERSA
                     IASTYLVFSTDSRELVGFFSLANRPLYFSKQNYQTLTKSQRKKISRSGRTLKGSGSFL
                     MNSFLIGQLGKNYKSNTSISGKELLTLACDKVKKASKIINTKYIWLECDNNPKLIQFY
                     QNFGFTPIDNFESENGLKVFVMKIQK"
     gene            complement(25970..26134)
                     /locus_tag="ACF4ZO_001181"
     CDS             complement(25970..26134)
                     /locus_tag="ACF4ZO_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486731.1"
                     /translation="MATKTFTRDFSFTAESADSLIRALNRNVTPKTVDVSHIKELTAE
                     AEIKAFFGKK"
BASE COUNT         8046 a         5710 c         4828 g         7697 t
ORIGIN      
        1 cctggcgcag aggctcctga taaggggtgt ggtcagtcgg atttccacta tcaagagcca
       61 acaaacgggc tggtccttct acttgaacct gcaaccaatc ttgagcatgg ctgaccaatt
      121 cacctcggct atccaagagt gataaatcca gataaagcaa ttcccaagga gcgtcaatag
      181 gtgcttcaaa ggctttccaa gatagctttg ccactgaacc ataggttcta acctgagaac
      241 gtccactggt ttttggaatg cttttaccag aaatgtcgta ggccactgcc cttagcaacc
      301 ctttttgata gggcactcgc caagtcagat aaaggttctc gtgaggattc ttagcagcgt
      361 cagctccttg gtaaagctga taagtgtgtc ccgttggcgt gctataagta tgaaatgcct
      421 tccttccata atctgttacg ttgccctgct catcttcaaa catcagttgc acactggcag
      481 cattgctata aaccacaacc tccaccaatc cctgctcatc gaaacaaagc tggtccttct
      541 gccagactgg taacaggtgc aaggtggtct gcccctgcgc ccactgactt tggtaaaaat
      601 aatagctatc ttttggaaag cctgccgtgt ctaaaatgcc aaagtaggca tttttaggag
      661 aaggccaaag gcctacaaca ccgctgtcga tcttgttcca gggggtaggt tctcctaaat
      721 aatcaaagcc tgtccaaacg cattcgccag caacaaaatc acgggtaatg gtatcatacc
      781 aagcctggct agcgaaggca ccccaatcaa ccttagcatg atcataagag gttaggtgat
      841 aaccggagtc aagaactttt tttgtctctt tataataagc cctgctggta atggctgagg
      901 ctgtttcaga accatacaac agccaatcag agtgctcctc atgaagctta tcatagtctt
      961 ttccattagc atagtttaac ccaatgagtc cctggggatg gtctaattga ctaagaagag
     1021 ttgccatttg cgacacttcc tcatgccagc aaaagtcagc ttcttttaat ttattatccc
     1081 caaaggtaat gggacgtgag gtgtcaatag cagcaatcca ttggcacatt tgtcttgtca
     1141 gctctgggta atgactgaca tcggctgaaa aaccttccat caattcatta ccaatcgacc
     1201 acatcaacac tgacgggtca ttcttggcag accagaccat ggcctcaata ctatactggg
     1261 cccagctcgt ttcaggtgac ctcactcttt gaagatagtt tgcattttca gttccgatgg
     1321 tctgatggaa atattttgaa aagtcattaa catttccatt tttggcatag gtccaggtgt
     1381 caaaggcttc ttcaatcaca aaaaagccga gacgattggc tagttgccta agtttgggac
     1441 tacttgggtt atgggtgcta cgaatggtat tagcccccat gtctttcaac aggactaatt
     1501 gtctggctag ggcatcttcg taagcacaag ctcctaggcc tccttggtca tgatgcaaac
     1561 aaactccctt taatttgaca gctctgccat tcacaaaaag cccctgatta gccgtaaaag
     1621 tcagctgacg aaaaccagtt tcaagggaaa agcaatcaat gacctgacct tgatagtaaa
     1681 gagtgagttc taaatcgtag aggtgaggat tatctggtga ccacaattgg agttcttcca
     1741 aagacagtgt aagaccatac tgtctttgga aagccaaatc agctagaggc acttctgttt
     1801 cttgataaag gagttttttg tcttttgagc aatgtgattg ttcccataaa cagaggctca
     1861 attggtagtg gcaagtctga atagactgat taagggcaaa gcgtaaatca actttctgtt
     1921 gccctttctc ctgcacagca gtatcagcca aggtcattgc tacctggtct gccacaaaat
     1981 gaagctgggg aagaacagac aaactcactt cacgataaag accactgcct gaataccaac
     2041 gagaactggg aaccttgttt tcaacccgga cagccagaag attttcagct ccaaaagtca
     2101 ctacatcaga gatatcatag gtaaattcct gatagccatt taagtgtttg ccaatgaatt
     2161 gcccattaac ataaatttcc gtttccatat aggaaccctc aaaagtaatg gcaacatgac
     2221 aaccagctaa aacctcatct aacacgagat aatgccgata ccaaccgaca ccacctaatt
     2281 tataagcact ttcagcttca ccatttcttg tgtaaggctg cgtaagactg aaatcatgcg
     2341 gtaaatgaat cacctgccag ttcgaatcat caaaagaagg ggcctgagca cacgccacat
     2401 ctgccataag aaaacgccag ccttgattaa agggctgctt tcttccttct tgatcaatat
     2461 agtggtattg gtagccagtc actgtctgct ccttgctatc tggtgtcata tcaatctcct
     2521 gtttaatgtt actggtcgcc cttgatggct tggtaattgt ccttgtaacg atctctgaac
     2581 tcttttggcg ataaaccatt caacttttta aacatcttga taaaataatg attggtattg
     2641 taacctgttt cataagcaat ttcattgatg gattggttgg tataaagcaa taactgttgc
     2701 gctttttgaa tcctaacatg atttaagtac tgggtaaaac tacgctcggt ttcattttta
     2761 aagcattgcc ctaaataaac cccattgaca tgtaaccgat cagcgatagc tttaagggtt
     2821 aattcttgat ggtattcctt gcgaatgcaa tcaatggttt cactaactaa atctgaatag
     2881 cgtttttcag gggaattgtt ctgattggtg acgtccaaca ctttttttag ttccctcaaa
     2941 atgcgatcaa tggattggct gtcatggata gtttttacca tggacagata agtcatttta
     3001 tctaaaatgg gaaattgacg gtaaatgtca gaaaacaaca agaacgaaac atgcttcaca
     3061 tcctctggtg aaaagttcaa ggtcttcatc tcgtcaaaaa tagcttctaa tttagacaag
     3121 attgtaggtt cgtccccaat catcaacgcc ttgttaaaag caaagaactg caaacgggac
     3181 tctggtagtt caattttgga cttatctttt gctctaattg gtgacacttc acaattgtaa
     3241 aagaggctct taagcacctg attgtagctt tcataaacat tttcccagtc atcaactgtt
     3301 tctcccaaaa taagttgatg catgtttctt gagaatcgct tttgtagatc ataggtaaat
     3361 gccttggctt gatcagtttt accaagtagg acagccagat aaactttctt atcttcttct
     3421 tttttgagat aaaaaggctg accttctcgt tcaaaataag catcgatggc tgcttgccac
     3481 tcttgacagt ccaaatacag cgctgtaaaa ccagttaaag cagccgctgg caagccttga
     3541 cttagctgct gaaattcttt ctcactcaat tcatctgtaa gccaaagggt caaaaggctg
     3601 tcatgatagg cttcttgccg gattgattct gcctgctggg catccaacca gtctttaaat
     3661 tgtttcattt tagcctgtaa ttctgcctta tccacaggtt ttagcaaata ccccttggtt
     3721 tctaattcca tagccttttg cacataggag aattcttgat aaccagataa aatcaaggtt
     3781 tgtagctgag gatgataggt tttagctgct tctattaaat ccagtcctgt cattccaggc
     3841 atggtaacat ctgaaatcat gacatccact gggtactgag tcaaataggc taaggcttcc
     3901 ttgcctgatc ttgctgtttg aaccacttca aatccaagtg cctgccaatc aataatcatg
     3961 gtgagccctt gtaaaatcat gtattcatcg tcaactaata gtaccttata catcaagcat
     4021 cctttctaat cctaatttga atgataaagc catcatttgg ctccttagcc atggaccaag
     4081 aaaccctgtc tcgaaaatga tggaaaagac ggaggtaaac attttgcaaa ccaatagagc
     4141 tattgcctgt tgtttggtgc tcttgaagcc ttcttttcat atctgctagg cgctcttgac
     4201 taataccacg tccattatca agcacctgaa tcaagagatg atccgtctca tctaaagcct
     4261 tgatgcttag tgcattgtca tggcgactat aatcaatccc atgcacaaaa taattttcaa
     4321 cgagaggttg aatgacaaat ttaggaatgg ctaagtcagc aatactctca tcaattttta
     4381 catgataagc gaagctatct ggataccgca tttgataaag gtaaatgtac ttttcacaaa
     4441 aagccagttc ttcttttaag gtggtcatct tatcttggct gatgttgttg cgaagcagac
     4501 tcgcaaaggc ataaatgaca tctgctaatt cttcttgttg acaactaagg gcgtacatcc
     4561 gaatatactc taacgtgttg tataaaaaat gagggttgat ttgagactgc agagctctca
     4621 tttgggcatc tcgttgctct acctctaaca cataaacttc gtcaatataa gctttaatgc
     4681 tggccaacat ctgattaatg gcttctgaaa tatgatacag ttccaattcc atgtggctgt
     4741 tgtcgatggt taaagacaaa tcgcctgctg caaccatttc aacagtatcc gtaatttcag
     4801 aaacctgctg gatataattt cggaaaaccc taaagagcaa ctgcaataac agccaagcta
     4861 agagtagaga aacaaggcca tacacaaaaa ctgtcctgac agcttccgct aataaatagg
     4921 attttctgac agccacataa gctaagaggt ctcccgagcg attgtactgc atccgataag
     4981 ccttgctgag attactaaga tcagctgccc gatctgcctt gatagccttt ttaacctcag
     5041 cctctaaatg aggaaatctc cgacctcctt gatggaagag tttgcggcca tagtaatcaa
     5101 aagcaaaagt agctaaatag tgatcctgct gtgtctctac caaagtcggt ggtttgtcaa
     5161 aagtcaggta aagacgacct gtcacatctc ctgattctgg atttcgaata gagcgaacta
     5221 aaacatttcc ggttactttt tcaggcttgc tataaagcaa acgacccgtc ttaatgacct
     5281 tatcggcgta cagataagca ctactgtcct ctagcagtag ggtcatagaa gtcacatcag
     5341 ggtacaagtc aaaaagacgc ctcacctctt cagaaaatag gaccgtgtct tttccttttt
     5401 cccagtcttc aaaaacgttt gaaaaatatt ggtttggggt taacgtcatg tattgataga
     5461 gattatggta atcttctgaa cggccaacca actggtctaa aacccgtagg gtaatatcgt
     5521 tttgtgactg caatctacct agagtctcct ccaatcgcat ctgcgcctca gcatccaccc
     5581 ttttataagt actactaata gaataactgc tcaagccaat agctgctaaa gtgaaaaaac
     5641 ttacaattag cagactatat aatttcatca gtcgattaat caaaaaaccc tgcttaaagt
     5701 ggttagtcac ataccttccc aatgttttaa cactcatcaa tcactccatc tactagtcga
     5761 cgattagcct tagtgacaaa gtccaagcaa aagactagag ctccgaaggt taaaaagaga
     5821 taaagacctt tgtattgcca agtcactaag gtaattccca acaaaacact cagcatgagt
     5881 aaaaaggatt tgaaacttaa aaagacgctg ataaaggcta atttcatatt attccaaagg
     5941 ttaatctcat agctcactgc ataaaaaacc atgtaaagat aggtcatggt tagccaaacc
     6001 atggctatta caatcaagaa agacacggta aaccaaaaca aggatggaaa ctgtactgcc
     6061 caatgcaaat taaaggttaa aaaaaggaaa gtcagggcaa aaagaccaaa tcttagatta
     6121 gcttctttga aataagattt ccaaagttga acagcccttt tcaaagaata gtggttttct
     6181 tcttgaggtg tttttaaaaa tagggtgaca atggtttgcc aggctggccc caccccaaac
     6241 acaatcagtc cagctaagga caagagatga aaaatgaggg tcaattggat cattttccaa
     6301 attaaaaagc aggttttttc aatgccattc atatgatagt cctctttttc ttgttaacac
     6361 ttatagcagt ttcagggacc agcagctacg agactagttt tagcaccccc agtaagatgc
     6421 tggtattagt tttactctga ttaatagttt agactcttct aatatagcac actttatagg
     6481 cttttggaaa ccgctttact aagagtagta acattatttc cattaatttt tctcccttta
     6541 taacttccac ttatttgatg atccgttttt tccactcatc agaagaaaag agctgagatt
     6601 tcccagccct caacttataa tcaagaaaat gaatgcctta cttgtcttta gctacaaagt
     6661 cgtccaattg tttttgaact tctttttgca ccttgtccca accagcacct ttgaggtctg
     6721 caagaagttt tggaagggct tcgtcaggat ccactgtacc agtattgata cttgctttat
     6781 atcggttcat gacatttgaa atatttgaca attccgtttt gataactttt gtgtcaacag
     6841 tgaaaccaag gattggagat tctttagcat ccttgattga ttggtcacgt ttagcaatca
     6901 tgtcgtcagt aacagattct tgagtgtaaa ggattttatt gttaccagta ttccaagcac
     6961 ccatgtgcat ttttggttga tagccatcga gcagtttgat tttcttgtcg ccaatttttt
     7021 cccaagcttt gccttcgaca ccataaacaa gcccatttaa caattcggga tcgctattaa
     7081 gaagagaaag gacttcaact gctttttctt tgtttttaga tacgcttgat accacaaagt
     7141 ttgccatttg tgcttgtgat gtggttttta gcggtttagt caatggacga gacacgatgt
     7201 cttttcctgc agcattggtc aagatagtat cgccatagtc cataggacct tgggtttctt
     7261 cacgcataaa ccaagtgttt ccttcaaggg gataaccttc tgtattggtc gctgcatctg
     7321 ttggaatcaa accttcttta taccatttgt gcatcaagcg gagattgttt ttaaaggact
     7381 catcttcata ctgattaatg atggttggct tgccttcatc aattttcaca gcaaagggtt
     7441 ggtttttggt taatgggtag tcatagtcac ctgacatact aaagacttga ccaatagcaa
     7501 aagctgctgt atttggttct ttttcgtgaa attgtttcaa gacattttca gcatctgcat
     7561 aggacttaat gtttgaaatg tcaaggccat atttgtccac tagttcttta ttgaaagaaa
     7621 gcacctgttg ggcataaacg ttggcatcta ctgggaaggc atagagttta ccgtcaatag
     7681 tatttccttt aatataggct gggtctaagt ttttatacgt tttcttagcg tattttggca
     7741 ttaacgttgt caaatcagca aaagtacctt tttgtgcatt gaccacataa ttattggcaa
     7801 aagcaatgtc gtagttttca ccagaggcaa tgatggtgct cattttatca tcccagtccc
     7861 cccaaccgat gtattgaagg tcaaccgttg cacctgtttt ttctttgatg cgcttgttag
     7921 caattgtcat caattcatcg aagttatcag gtttgtcacc aacttggtac atcaataatt
     7981 tgacatcact atcctttgat gctgacttgc tttcgcaggc tgctaaacta gacgctgcaa
     8041 gcacagttcc agtcacacac acgatttttt gccacttttt cataagtgaa gcctcctaaa
     8101 aaatgttttc ttttgttact aatgattaga taaaatctgg tcttgtgacc agttccttaa
     8161 gtcctattcc ttcaccccac caatggtcaa accaccgaca aagtactttt ggaagaatgg
     8221 gtaagtcaag gcaatcggca aggttgcaat aaccacgata gccatacgaa ctgattcttt
     8281 tggcagcgat gctaagctat ctgccatttg tgcactcatg ccagcatttt gtgccaaggc
     8341 ctgtaggttg ctctgaattt tcatcagtaa gtactgcatt gggtaaagat tctcactttg
     8401 cacataaagc aaggcgttaa accaatcatt ccaataagtt aaggcagaaa ataaactgat
     8461 ggtggcaatc cctggaacag ctaatggtaa gacaattttc ataaaaatca tccattcact
     8521 agccccatcc atacgagctg attcaataat gctatctgga actgtctttt taaagaacgt
     8581 tctcatgacc aagatgccaa atgggcccag agccattggt aaaatcaagg cccaaaccgt
     8641 atccttcaaa tgaaggagat tgctgaccac caagtaatta gcaaccatcc ctggtgcaaa
     8701 gagcatggtg ataagtgcat aaacagtaaa aaaacgtctg tatgggaaat aaggtcttga
     8761 aatcgcataa gcataggttg atgtcatggt cgtgttaata aaggttccca ccactgtaat
     8821 aaacacggat atcccaaatg acctcatgat tctatgggac atggctcctt gaaaaatata
     8881 ctggtaagcc ttagttgacc agacatctgg aaaaaaacta tacccatgat taatcaagta
     8941 actttcatca gtgaaggaaa taataatcac gaagataaaa ggaatgatac aagagatggc
     9001 aaacagacca atcagaatat taaagatagc attggttttt cgatcaaagg ttctaacatt
     9061 aaccttttcg acttttttct ttttctccat ggtttcctcc taaaacaagg ctgcatcagg
     9121 gtccatgcga cgaacaatcg cattggtgac taacaagatg ctggtcccaa ctactgactg
     9181 ataaaggcta gctgccgatg ccatcccaat atctcctgta gcagtcaagg cattgtagac
     9241 ataggtatct aacacactgg tcacgtcata aagtgggcct gaatttttgg gaataacgta
     9301 gaaaagtccg aaatcagatt taaaaatatt accaatatta atgatcaata agatagacat
     9361 cattggcaat aattgtggaa tggtgatgtt cctaatttgt tgccatttgc ttgcaccatc
     9421 caccatagca gcttcataat aagtatcaga aatccctttg actgaagcat agtagataat
     9481 gctattgtag cctagcccct tccagacact catgaaaagt aaaatcaagg gccaccaagt
     9541 gggattggaa taccacttga ttggagctcc tccacttcca gtcaagagct gattaatgaa
     9601 acctttatcc gtatttaaaa aggcagaaac aaagtattca ataaccaccc atgataagaa
     9661 ataaggcaat aaggacatgg tgtgatagac cttaaccgtt cgcttatttc gtaactcact
     9721 catgataatg gcaaaagcaa tcgcaaagaa aacattaaag agtaagaaaa tcacattgta
     9781 agcgatggta tttctggtaa tcaaccaagc atctttggaa gcaaagaggt atttgaagtt
     9841 agccaaacca acccaagggc tctccttcaa actttccata aagccccctg ctgagtaatg
     9901 aaaatcttta aaagcaacca cattggctaa aactggaata taaaagaaaa agatgaacca
     9961 gatgaaacct ggtaatacca ttaataataa ggcccggtat ttaatcacat ttttccaaaa
    10021 ggatgtcttt ttgttggttt gtcttgtcat ttcccaacct ccctttgtgt taatcacgtt
    10081 atagttacag tatatcaagc gctttcatga tttaaaagca acaaaatata ggtatgataa
    10141 cacaaattat aggtatgata gcacaaaata tagaatcact tagaaagcct tttcattgtt
    10201 gcttaaatct gtcatactaa gatgagacat gatcgtctat tctactacaa taaaggagaa
    10261 cacctcatga gcttgttatg tcttgatata ggaggcactt cccttaaatt tgccctctgt
    10321 cacaatggcc aattaagcca gcaaagcagc tttcccactc cctctagtct ggaaaagttt
    10381 taccaattac tcgaccaaga agttgctcgt tactctgctt accatttctc aggtattgcc
    10441 gttagtgctc ctggagcggt taacaaggaa aaaggtatta tcgaaggagc cagcgccatt
    10501 ccctacattc accattttaa aatacaagag gccttagaag agcggctaca ttaccctatt
    10561 tctatcgaaa atgatgccaa ttgtgccgcc ttagctgaag ctaccttagg ggcaggaaaa
    10621 ggcgctagta gcctagccat gctcgttctt ggtactggag ttggaggaag cttggtcatt
    10681 gatggcaaga tttaccatgg tgcccactta tttgggggcg aatttggttt catgatcatg
    10741 aacgaccgct accaaacctt tagtcagtta gggacagtgg taaatatggc caagcgctat
    10801 agtgcaatcg tcaataacgg aaaagattat actggcaaag ctgtccttgc cctcgcagaa
    10861 caaggagacc ccctagcact caaagaaagg cgggtctttc tccaaagttt agccatcggt
    10921 atttttaaca ttcaacacgc ctttgatcct caactgattt taatcggggg tggtgtttcc
    10981 caagctgact ttctactgtc agcgattgaa gctgaactag acaaactcta ccaagccgtc
    11041 gaaatctccg accttagacc ccaattagcc atttgtcact ttaaaaacga agccaatctt
    11101 cttggagctg ccattgattt ttaccaagaa cacaaggagg cctaaccatg gactgctaaa
    11161 tccctcttat cccctattgt ccctaatcgc ctctgacatc tacaaagaca tcctaaaagg
    11221 attgctgatt agctacaacg atactggttt tctgcctaaa tgactctctg ctgatgaacg
    11281 cagcctgatg cctggtccct ttgttgatgt cgttgttgct gatgcttctg ttaaaggcat
    11341 tggtcatcag ttaatgctcg agctattaga agctatgcta gttatcgcca ataagcaaag
    11401 cctcacttaa taactcactc atatagtccc cttatcgtgg acagtgacat aacaaacagt
    11461 cactagaaac catgaggggc ttttatctgg tccaaaaata tgaaagaaaa tcctaaaata
    11521 ccaagatgaa aaacaagcat ccttagccaa gatactctaa agaattgaag agccaaatta
    11581 cccaaggtgg atagatgatg ccaaaccaga cagaacgctt atatctagtt cggcaaatac
    11641 caacactttc caaagaaata caagagcctc gatcctctta acatgaggaa aaaggccctt
    11701 gtttaatcat tggtaacatc attattcact tgtctcaaag gagacggtca cacgttcaat
    11761 cactgaggtg agaagcagag cctccaaact cctccattac ttctaatgaa atcaagcggt
    11821 tatgagtagc tactttttta aaccaataag ctgaagcttt aggtcgtcgc acttgggtat
    11881 ggatattatt ttccacaagg ccatagcggt ttttgtaggc attgagccaa gaccagccat
    11941 caattggtgt ccatacatgg taaccaaaac aattcgagcc tgcttctatt cctttgtgga
    12001 gataggttaa atgttctttc aaaaattgga tgcgataatc atcttgaatc tgaccagttt
    12061 catcacggta acggtcttct cctgaaatcc ctacaccatt ttcagataag aaccaaggaa
    12121 tattgtcgta atggtctcgc atcttgatgg caatatcata gacagcctca ggatagatct
    12181 cccacccctt atccacgttc atgcggcggc caggcatcag gtaggcgtca taataccatt
    12241 caggactcca agatgggcta atcactggaa tggcatcagg agccttcacg cgcttagggt
    12301 ggtaaaaatt caatcccaaa taatccactc tattctcagc aataagagcc aattcttctg
    12361 gcgttgactg ccacaaaacc ccatcttttt tcaataccgc aaccaattct tctgggaatt
    12421 tcccatgaac agcagcttcc ataaacaagt cattgttcca aagttctgca aaatgcgcag
    12481 cagccatgtc cgtttctgac tgactagctg ggtaggctgg cgtcagattg agaatggttc
    12541 caatacgccc attactaagc tttgctggac ctcgcctgta agcttgaata accttggctg
    12601 tggctagggc tagattatag gcgacctgca ctgctttttt cccatccacg atagcagggt
    12661 aatgaaattg cattagataa gagccttcca caacgaccat aggttcatta tgaacaaacc
    12721 aagccttaac ccgatcaccg aattcttgaa aacaaacctt actaaaggcg acaaataagt
    12781 ccacaacatg ctttgattcc cagccaccat aggcttgata gagggcaatt ggcaggtcaa
    12841 aatgatgcaa attaatgaca ggacgaatac cattggccaa gcaagcatca atcactcgat
    12901 tataataagc aaggccatca ggattaatcg tcacttgctc aaaatcatct atcaaacgtg
    12961 tccattggat agaggtacgg taggaattgt gacctagtga agctaacaag gccaaatcag
    13021 attcaatctg atgataggca tccgaagccg tatcaggtcc cacgtaatcg taaaacaagt
    13081 caggctcctc ttcataccaa taatcaaaga gattgcggtg ctgcttagca aaacgcccct
    13141 cactttgagg gcctgaggtg gctcctcccc accaaaactc ttttggaaat gctaacatat
    13201 cattcctttc tagccactag cggttaagca taatcttcag gtcttgcttg ggtaacttga
    13261 ccttgattag ctgttagttt atcttgctgt tgatagtaga tgcgatagta acgacttgga
    13321 atgtcacttc caatacggtg tttatcttct tgtaagtcag catagagtgt ttccaactga
    13381 ggctcctgat ttaacatagc ctgccaaaaa tcttggtctt tggccacccg ttcaaaccaa
    13441 ggagcaatag cttgttgaaa cgctggctta tctagctttc tcaacgtatt gacacgttcg
    13501 accaattcat ctacccaagc tgataacgtt gatacatcct tagccaggag agcttcttcc
    13561 acttcaaaag gaaggtccct gtgcagatga cgattgccat tatgccaagc aaatgcctgt
    13621 aaagctaagg ctaattcagc atctcctgta tagtctgtta aggtttctag ccaagaatga
    13681 ctaggctgat aacggttagc atcccacaga taatggctca tgtctgtcaa ggtcagctga
    13741 gataattccc aactaatcat agggttagaa acaatcccct tgacctgata gtctggctgg
    13801 cataaaaatg gcgagcgatt ggcaaaagga gttaaaaaga gacgttctgg atctttttga
    13861 taatcattaa caggaatatt gtcccaaata atgataggcc gttgatatac tgctgccata
    13921 gtttcaatat ctgcctgcga gatttgactc gctagcgtgc ttgggcctgt ccagaaaaag
    13981 gcgacttctt taggaatcct ttctgacagc tcttgcaaat agatagaatc atggtgatta
    14041 tcgtattctg tcggacagat caccaattcc ggggccgcat gttgttggtt taaaaagtga
    14101 tgaacctcag ttgccaagtg ggcctgggca taggcagtct ttttgaatcg tctctcaaca
    14161 gcatctacaa tttggtagtc aatatcatcc agcaaaagtc caaaatgaca gacacctaac
    14221 gctagaagtt gttgcaattt ttgatagagc aactgatagt cagcttcctt ggtataatca
    14281 aaatcaagtc ccggactaat catataccag aaatcaatcc cttgttcctt ggctactgca
    14341 agtagctctt tgaaataagt cacccaatcc tcaggataaa gatcgcgcca ttgttttcgc
    14401 tggtaatcat catctttcgg agcatacatg taagtattca tccttttacg tccaatgaaa
    14461 cgtaggcaat ctaaccgctc ttctcgtgtc cacggtgttc cgtaaaagcc ttcaattatc
    14521 ccccgcatag caaaagaagg actatgcttg acagatacaa tcggtaaata aagtttatcc
    14581 cctttgaaag tcatcacttt aagcaaagct tcttgggcgt aacgaaaacc tctaaggttt
    14641 tggctttcaa taataatttc cttatcttct gaaaccttca gggtaaaggc gtccttagct
    14701 agctgacggt taaaaaagtg tttcatcgtc acctctgctt ggccttcttc aatccactga
    14761 aaatactttg acgttgccaa ttctgccagc agggcttttt gattttcaaa acggaaaaaa
    14821 cgaccgacaa atcggcatgt caacagcatg tcaaggacaa gatagtctcc tcttgtcatg
    14881 acttcttgat aatcctttaa ggcgtgataa atggtcattt ctggtctcct ttacctgagc
    14941 taaccagctc atgctagtaa catctttttt agtgactact ttctctgata aatacttgaa
    15001 caggtaactg gcaagacacc actgcttggt ctggctcatg aataatctgc aacaagactt
    15061 tagctgcttc ttgccccatt tggtaaaaat cttgagctgc tgtgcttaat ttgggactca
    15121 acaaacggga ggcttgacta ttatcaaagc ctacaatagc gacttgatca ggaatagata
    15181 agcctacctg tgtgattttt tgaatcagct gaatagccaa ccaatcgttt tctacgacaa
    15241 gccccctttt agtggctgtc gtttccgata aggttttcac caaacggttc agataagcat
    15301 cagaggtttc agctttttcc ttgggaaaat accaggatgg caaagaagtt tctgccattg
    15361 ccgctaaata acccaaataa cggtctctga ccgatgacac ttccccaaaa gagcctgttg
    15421 ccacaaaact aatctggtca cagccttgct caatcaagtg ctgagtcaat tgatagacac
    15481 cgcctttatt atccgctaca acagacggaa actgaaaaag atccagagat ttatccaaca
    15541 agactagagg aatgtgatga tggtcgcagt aaaacaggaa atcaatactg tgattgacat
    15601 cttctgggta ataaataatc ccagcatagt ctgatagagt gtctaacctt accgtactgg
    15661 ccaattgaac catgagacgg taacctgttt cagcaatgga ggtcataatt cccttagcat
    15721 aatcccccaa ttcataatct gaggcaaaag gaagaatcaa caataaatcc ttattcgctt
    15781 caggggacgt cacttgcttt ttagctacga agcttccttt cccacgactt ctcgtaatca
    15841 agccttcttg ctccagttct acaagcgctc gcttagaagt aatacggcta accgagaact
    15901 gttctgacaa ttctttttca gtaggtaggc ggtcaccaat ttgcaaacga cctgatgcta
    15961 tctgctcttt aatgaaatga tatatctttt tgtataataa ttttgtcatt ctttactccc
    16021 gttatcagta tagcatgtca aaaaagagtt gtaaaccttt tcaaaaactt atagacaaag
    16081 tttaatttat catttataat gaaaccgaag atgaatgata tatcatttcg gaggatatga
    16141 catgacacga ccaatcccaa ctagcgtcag ccaatttatg gccaaggtgg aaagcctttg
    16201 tggagaccaa caccctgatt gggctcttaa tttcaaaaca agctttgcca ataccttaga
    16261 gacaacccta aaaacctacg aagatggcac tagctttctc ttgacaggag atattcctgc
    16321 catgtggtta cgtgattcca ctgcgcaaat gaaaccttac ctcttcctcg ccaaggaaga
    16381 tgaagaaatt agaaagatta ttgccggtct ggtcaaacgc caattccgct acatttgtat
    16441 cgatccctat gccaatgcct tcaacgaaga agctaacgaa aaaggacacc aaacagatca
    16501 tacccaaatg aacccttgga tttgggaacg caaatatgag attgattccc tttgctaccc
    16561 tattcaactg gcttatctgc tctatcgtga aacaggaagc accgatcagt ttaatgacga
    16621 ttttcatcgt ggggtagaac tcattcttga cctatggaca gttgagcaag accacgccca
    16681 gtccccttac ttgtttgaac gcgatacttg gcgcaaagaa gataccctaa cacatgctgg
    16741 aaaaggaagt cctgtcgcac caacagggat gacctggtca ggctttagac caagtgatga
    16801 tgcttgtcaa tatggttacc tcattccttc aaatatgttt gcagtggttg tgctttccta
    16861 tctagaagat ttatataaca acctttttca caatgaatca gtagctactc gtgccaagca
    16921 gctgaaagaa gctattcaat cgggtattgc agaccatgcc cttgttcaaa acagcaaggg
    16981 agaaaccatt tacgcttatg aagtggatgg tctgggacag ttttccatca tggatgatgc
    17041 taatattcca agcctccttg ctgcacctta ccttggtttt tgcgctaaag atgaccctat
    17101 ctatctggca acgcgccgca ccattctcag ccaagaaaac ccttattatt atcagggaaa
    17161 tgcagcagca ggcatcggtt cttcccatac accagaaaat tatatctggc atatcgccct
    17221 tgccttacaa ggattgaccg ctcttgacca agacagtaaa aaagagatgc ttgatttgct
    17281 tgtggcaaca gatgctggta cccacttaat gcacgagggt ttcgatgtca atgatcctta
    17341 tcaatacact cgtgagtggt tctcttgggc taacatgatg ttctgtgaac tacttcttga
    17401 ctatctgggc tttagtattg ctccttagaa agtgaggcca ctatggcaac taaaaaagta
    17461 catattattt cacacagtca ctgggatcgc gagtggtaca tggcttacga acaacaccac
    17521 atgcgtctga ttaacttaat agatgacctg ttagaagttt ttcaaacgga tcctgatttt
    17581 catagttttc atttggatgg gcaaaccatt attctagatg attatttgca agtacgcccc
    17641 gaacgagaac ctgagattag acaagccatt gcttcgggaa aactccgtat cggacctttc
    17701 tatatcttac aggacgattt tttgaccagc agcgagtcca atgtgcgcaa tatgctcatt
    17761 ggcaaggagg gttgtgacaa atggggcgct agtgtgccac ttggttattt tccagatacc
    17821 tttggaaata tgggacaaac accacagctg atgttaaaag ccgacctaca agctgctgcc
    17881 tttggtcgtg gcattcgtcc aactggattt aacaatcaag tagataccag tgaaaaatac
    17941 agctcccaat tctctgaaat cagttggcaa ggaccagatg acagccatat tcttggactc
    18001 cttttcgcca actggtacag caatggcaat gagatcccga caacagaagc tgaggcgcgt
    18061 cttttttggg ataaaaaact tgctgacgcc gaacgctttg cctcaaccaa gcaccttctc
    18121 atgatgaacg ggtgtgatca tcaacccgta caacttgatg tcaccaaggc aatcgcctta
    18181 gccaaccaac tctatcctga ctacgaattt gtgcattcct gctttgaaga ttacttggct
    18241 gatctcgcag atgatttacc agagaacctt tcaaccgtcc aaggagagat taccagtcaa
    18301 gaaaccgatg gctggtatac cctagctaac acggcttctg ctcgtattta cctcaaacag
    18361 gctaatacca gagtctctcg ccaactcgaa aacatcaccg aacccttagc agcaatggct
    18421 tatgaggtga caagtatcta ccctcacgac caactgcgtt acgcttggaa aaccctcatg
    18481 caaaatcacc ctcatgattc tatctgtggt tgtagtgttg atagcgttca tcgggaaatg
    18541 atgacgcgct ttgaaaaagc ctatgaagtc ggacattatt tagcaaaaga agctgctaag
    18601 caaattgctg acgccattga taccagggat tttccaatgg atagccaacc cttcgtctta
    18661 tttaatacca gcggtcattc caaaacaagt gttgctgagc tcagcctgac ctggaaaaaa
    18721 tatcattttg gccaacgctt tcctaaagag gtttaccaag aagctcaaga atatttggca
    18781 agactctccc aatctttcca aattattgac actagtggac aagtgagacc cgaagcagaa
    18841 attttaggca caagcatcgc ttttgactac gatttgccca agagattctt ccgcgaacct
    18901 tatttcgcca tcaaagtgag attacggcta ccaataactc tcccagccat gtcttggaaa
    18961 accttagcat taaagctagg aaatgaaaca actccttcag aaaccgattc cctctacgat
    19021 gacagtaatc agtgccttga aaatgggttt ctaaaagtta tgatacaaac cgatggccgt
    19081 ctaaccatca ccgataaaca atctggacta atctatcaag acctgttgcg gtttgaagat
    19141 tgtggcgata ttggaaatga atatatttct cgccaaccaa ctcatgacca acctttctat
    19201 gcggaccaag gcgtaactca tatttctgtt cgcaacaaca ctattcaagt tgctgaactt
    19261 gaaatccagc aaacctttac cattcctgtc tccgccgatg accgcttaca ggctgagatg
    19321 gaagctgtca ttgacatcac agaacgccaa gcaagacgtt cacaagaaaa ggctgagcta
    19381 accttaacaa cccttatccg catggagaaa aacaatcctc gcctccaatt taccacacgt
    19441 tttgataacc aaatgacaaa tcatcgcttg cgcgtcctat tcccaacgca ccttaaaaca
    19501 gaccatcatc tagctgacag tatttttgaa actgtcaaac gtccaaatca tccagatgtc
    19561 accttttgga agaatccaag taacccacag caccaagaat gctttgtgag tctctttgat
    19621 ggtgaaaatg gagtcactat tggtaactat ggcctcaacg aatatgagat cttaccagat
    19681 accaacacca ttgccatcac tctcttacgt tctgttggcg aaatgggcga ctgggggtat
    19741 ttccctactc ctgaagccca atgcctcggc aagcacagcc tttcttatag ttttgaaagc
    19801 atcactaagc aaacacaatt tgccagctac tggcgagctc aagaaggcca agtccctgtt
    19861 attaccacac aaacaaacca acacgaggga acattagccg cagaatatag ctatttgacg
    19921 ggtacaaacg accaagttgc cctcacagcc ttcaaacgtc gcttagcaga caatgccctt
    19981 atcacgcgca gctataatct ctcaaacgat aaaacttgtg actttagcct aagcctgcca
    20041 aactacaatg ccaaggtcac taatttgtta gaaaaagaca gcaagcaaag cacacccagc
    20101 caacttggca aagctgaaat tttaactcta gcttggaaga aacaataaac tattatcatt
    20161 agtaatagat taacatattc aaaaagagtc tgggactatt gtctcagact cttaagttga
    20221 ttttgagtga ttattaatac ctttaacatc agtcaggctt agctatttct attaactggg
    20281 ttaaaatgcc atcatgaatc tgcgagctaa ttgtgagata gtcataacga tttaaaatgg
    20341 tcgtgacatt ccttaagtca aattgccagt catctctttt tttcaaagcc ggtgtagcaa
    20401 acacgctttg actatcattt tgtccttgtt tagtactgct ttgaatgact atgacaagtt
    20461 tatggttttg atccagaaat gctattgata agcaaggttg ctttgtctcc aaactcattt
    20521 ctatagcatt atctaacaaa aatgacaata gcttagtgaa atctactagt tctagaaaaa
    20581 acgttgcaat acaattagga atcgatacct caaccttaag cttcttattt tttgcctcaa
    20641 ttaatttagc taaaacaata tgtctgattg cttcaacttg taatttatct aaacaagtta
    20701 aatcaagtct gtcatcttta gcattattct tttcagcatt caagatacct tcataagtaa
    20761 gtctcacaat agagatatca ttttgttcga ttccaatctt aagacgactg gacacggtag
    20821 ttaatagctg cctaagctct tgaatatctt gatacagcaa tccaaggtgc tgactataat
    20881 taatcagctc acgatattct ttttgttgca caattgcctc aatagagttt tgttttacat
    20941 aacgctctaa atgaattaat aaagtaagaa acaaaatgaa ataaaagagc actatgattg
    21001 aacgagcagt cgttgtagca agtcctgata aagaaggcga catcacatct atcccttgga
    21061 cacacaagta atatagagcc atcgaagagt tagtaaacac taatagttta ctagctctat
    21121 gtgattgaaa atattggcgc caggttgaaa aatcgaaatg aaaaacttga atgcagcgat
    21181 aaatcaaaaa aatactaaag caagtaatgc tgtaaatcag tagtgtatta tgtttaacaa
    21241 ctgaataagg cataccaaac aatggcataa caaaaaatac aataaatcgc ttaaccaaac
    21301 taatagacac tagtggaaaa aaggcataaa acattaaaaa cttagctttt attgatttac
    21361 catagtatag ggctataagc gcaaagaaaa gaaactgagc caacatcaca acatcaagaa
    21421 tgaaatggtc tggaaagaaa gcccaaaaaa ctacttgaaa caaaaccata ctaagtgata
    21481 aataaaaaat atttttcagg cgaagcggaa ttgcacttac aaagctaaaa agctttaacg
    21541 ttaacataat ttcaataata tctaaaaata taaatcctaa aaattgaaga aaatcttcta
    21601 acatttatcc ttctccttct cgttcaaaat atgttatcac atctcgattt tcttttcatt
    21661 tcgaactccg taatagataa actgagcttt ttcattttaa tcatattctt tattttatca
    21721 taagttctgt cattctaaca gttaaattac gaaaagcttg attaagtaac ttttctacat
    21781 tccgatcatt ttactggtta tcaacttaga tttatcagtt gttgatctca ttataaaaaa
    21841 gtgttgcatt tatctttagt atctaacaca taaagactca cacagcctac agtttttgca
    21901 aaggtttctt acagcttaaa agattaaatc aggataaatc ctctatatca tcgttcatat
    21961 tagcatacta aaataacttc tggtaatgta acctcctgac cactcagttt tctaatttat
    22021 agcaaaaaac agcttttttt caacaaccaa ttaccctaat attgtctgtg tgtacttgct
    22081 cttcaaatag accctactta gtgacaaact aacaaacttt ttttaaccat gaatgtttct
    22141 aaaataaaca tagagttatc aataatatga ctatgcttac taaaccgttt ttgacatccc
    22201 tactatgtca agctattgct caaacccatt acctgagctt ataaaacttg agttgttatt
    22261 ggcactcaat catacacgtt tttgtaactt cacgacagcc tcggtcctag ctgtatgggg
    22321 gaacatgtct acactttgga tatagtgaac atcgtaaatc tttgttagct gcaccaagtc
    22381 gcgggctaaa gtggaggtat tacaagacac atacaccatc tgtttaggct ggtaatgaag
    22441 aatcgttttt aataatttat catctaaacc agttcttggt gggtccacaa tgatggcatc
    22501 cgcgcggtaa ccttgtttat accatttagg aataatatcc tctgccttcc ctgcctcata
    22561 gtaagcgttg tcaaagccca tggatttggc atttttttgt gcatcctcaa tcgcttctgg
    22621 gataatatcc atcccccgca cagacttgac cttccctgca aaagcaaagc caatcgagcc
    22681 aaccccacaa taggcatcaa taatatgatc tttgctccct acatccaagg ccttcaccac
    22741 ctcaccatac aaaacttctg tctgctgtgg attaagttgg taaaaagctc tcggtgataa
    22801 cgcaaatcca tagtctaaaa cttcttcatg aatcgcctct tgtccccata gaatttccgt
    22861 ttcgtcccca taaatctcac tcgatttaga acaattacta ttcaaggcaa ccgttttaac
    22921 ctgaggaaat gccttagtca attcgccaat gaacctcgct aacctaactt ctttgctact
    22981 cacaacaata atctgtacct gatcactagc ctgtgcctta cgaaccatta tcgtccgaat
    23041 cccagcaatc tttcgctcat tgtaaatggg caacttgtac ttgtccacta actgcgtaat
    23101 cttattgata atatcttgcg ttagttgatc ctgtaccaag caattgtcaa taggaaccaa
    23161 gcgatgactt ccctgggaaa ataaaccagc cttgaccgtc ccgccaaatg accgcagctg
    23221 aaactgcaat ttggcccgat agtgatctgg ctttttcatt cctaaagtcg gtctaatctc
    23281 aaattgttca tagccagttg gtttgaactt tttaagggcc tgcctaatca catcatcttt
    23341 gaaatctagc tgtttaggat aggctagatg catgatttgg caaccaccac aagtttcata
    23401 aacagaacaa gctggtttga cacgattctt agaagccttg tttaccatta acagtttggc
    23461 ctctgcaaaa ttccgtttaa ccgccgtgat ttggcaaaaa atatcttctc cctttaaagc
    23521 accagggaca aataccaaag ttttctgata aaaaccaatc ccctcaccgt taattcccat
    23581 tcgcttaatt tttaaaggaa ttttctgttt aacctttacg accatctctt ccccttagtt
    23641 cctctaatat cctaatctca ccaccaaaag cattcacaag caacacattt ttagcagtat
    23701 tttcattttc tattttacca tttttgatat aatgaacata tagataaaac tcctaaaatt
    23761 gtggctttac aatgtcgttc ctcgactatt ccccgacttc tggacgaggt cttttttatt
    23821 tgtctaattc caccatcact tcttccacta cctcctcggt cacaacttct ccatttctcg
    23881 cttcttcatg cggcaacaca taatcaaaaa tctgtccgtt tttacgcacg atcataactg
    23941 tgtctgctgt gatatatcca ttgtcaatcg cttgcttaaa ttcgtcgtat gttagcataa
    24001 attacctcct tatcttatta ttcgtatttt acaggaaata acataattaa atttacagct
    24061 tatttaaaat taaataacat ccatttttgt tacaaactaa aatatttatt attagcgaat
    24121 attaaataaa aagaaatttt agcgtaatat tattgataaa ttaattttat taattttaag
    24181 tttttttaat ttaaagtgat ataattaacc tgtaaataat aaaaggggga catggatatg
    24241 tctaaacatt ggaaacatct attcattcgt tatactttta ccgctctagc tactttattt
    24301 ctagggctat tcccaatatc taaaactact aatagtatta tttatgcgga aacaactgat
    24361 atttcaaatg tttggaacat agtacaacat ccaaactatt atattgtcga aggcaaatcg
    24421 catttaaata aagagaagtt ccctcaaatt tatcatacaa ctgaaaaagt ttatagaaaa
    24481 agcggacaaa gtactaagcg cgttaccgtc tctgatattc aatactctat tcttgatggc
    24541 tatggtcgtt ctggagaagc ttatggagtt atcacaaagg acatgattga catgtctgct
    24601 ggctatcgtg aaaaatggga aagcaaacca gagccaagtg ggtggtattc ttatttcttc
    24661 aaaaatacta accagagggc tactgaatcc gattacaagc atagccccaa aaatgtgagt
    24721 aagatttcaa ataacatcaa ggctagtatt cctttaagta acggtagaac tcgacacggc
    24781 tatctcttcg accgtagtca tcttattgca gacagtttag gaggaaggcc ttttagaaat
    24841 aatttgataa ctggcacccg tactcaaaat gtaggtaata atgatcgcaa aggtggtatg
    24901 cagtatattg aaaataaagt tttagatcac attaaaaaaa accctaaagt ccatgtttac
    24961 tacaaagcaa cgcctgtata tcaaggaagc gaattactac ctagagtagt tttagtatct
    25021 gccttatcat ctgatagaac aattgacgaa acagttcgtg tcttcaatgc tgtagcaggt
    25081 tttaatatcg attaccaaaa cggcggtctt ttaacagaaa gccctgtaag tgaaattggt
    25141 aatattgaag attctacaac agacgaaata gaaaattctg tggatgattc agaagaaata
    25201 gtttataacg atattactac cgaagaagta aactaagatt tcatcaaatt tagataacac
    25261 aaaaaaccgc cctcaactaa gagagcggtt ggttttttat ttcggctaat tcttactatg
    25321 gtaatttgtt catgattgtg cgggagtgtc aatgaaggta agagaaatcc aatttgttat
    25381 ttttgtatct tcattacaaa aactttaagc ccattttcgg attcgaagtt atcaattggg
    25441 gtaaatccga aattttggta gaactgtata agctttggat tattatcgca ttctagccaa
    25501 atatacttag tattgatgat ttttgaagcc ttcttaactt tatcacaagc taatgtaagt
    25561 agctcttttc ctgatataga ggtatttgat ttataatttt tacccaattg accaatcaaa
    25621 aaactattca ttaaaaaact accgcttccc tttaaggtac gacctgaacg gcttattttt
    25681 ttgcgttgac ttttagtcag agtttgataa ttttgttttg aaaaataaag aggtcgatta
    25741 gctagcgaga aaaaaccaac cagctcacgg gaatctgtag aaaaaacaag ataagttgat
    25801 gctatcgctg agcgttcaaa ctctactgct ttttgatgca aaaagacttc tacatcatgt
    25861 ggtgtagaag ttccgtcatt gaatcctttg aatgatttta gaagttgctg aatttcttct
    25921 ttttctaaat atttcattat ttcatcgagt gaaattgttc tatagttcat tattttttac
    25981 caaaaaacgc cttaatttct gcttctgctg tcaattcttt gatgtggctc acatcgaccg
    26041 tcttgggggt tacgtttcgg tttagtgccc taatcaaact atcagcactt tcagctgtaa
    26101 aactaaaatc tctagtaaat gtttttgtag ccatactgac aacctccctt ataatgtatt
    26161 tcaggagtag cactccagct actcctcacc ctcattatga cacgccttga actttttgtc
    26221 aataaatgcg aagttttttg cgaaaaaaca gcccccgcaa aaagcgaggg cgtttgtctt
    26281 a
//
LOCUS       DAXMQE010000023        25939 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.023, whole genome shotgun sequence.
ACCESSION   DAXMQE010000023 DAXMQE010000000
VERSION     DAXMQE010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25939)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25939)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25939
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.023"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            16..89
                     /locus_tag="ACF4ZO_001182"
     tRNA            16..89
                     /locus_tag="ACF4ZO_001182"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:50..52,aa:Arg,seq:acg)
     gene            96..169
                     /locus_tag="ACF4ZO_001183"
     tRNA            96..169
                     /locus_tag="ACF4ZO_001183"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:130..132,aa:Pro,seq:tgg)
     gene            175..248
                     /locus_tag="ACF4ZO_001184"
     tRNA            175..248
                     /locus_tag="ACF4ZO_001184"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:209..211,aa:Met,seq:cat)
     gene            269..342
                     /locus_tag="ACF4ZO_001185"
     tRNA            269..342
                     /locus_tag="ACF4ZO_001185"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:303..305,aa:Ile,seq:cat)
     gene            365..454
                     /locus_tag="ACF4ZO_001186"
     tRNA            365..454
                     /locus_tag="ACF4ZO_001186"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:401..403,aa:Ser,seq:tga)
     gene            464..537
                     /locus_tag="ACF4ZO_001187"
     tRNA            464..537
                     /locus_tag="ACF4ZO_001187"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:498..500,aa:Met,seq:cat)
     gene            558..630
                     /locus_tag="ACF4ZO_001188"
     tRNA            558..630
                     /locus_tag="ACF4ZO_001188"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:591..593,aa:Phe,seq:gaa)
     gene            650..730
                     /locus_tag="ACF4ZO_001189"
     tRNA            650..730
                     /locus_tag="ACF4ZO_001189"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:684..686,aa:Tyr,seq:gta)
     gene            737..807
                     /locus_tag="ACF4ZO_001190"
     tRNA            737..807
                     /locus_tag="ACF4ZO_001190"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:769..771,aa:Trp,seq:cca)
     gene            819..891
                     /locus_tag="ACF4ZO_001191"
     tRNA            819..891
                     /locus_tag="ACF4ZO_001191"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:852..854,aa:His,seq:gtg)
     gene            900..971
                     /locus_tag="ACF4ZO_001192"
     tRNA            900..971
                     /locus_tag="ACF4ZO_001192"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:932..934,aa:Gln,seq:ttg)
     gene            991..1074
                     /locus_tag="ACF4ZO_001193"
     tRNA            991..1074
                     /locus_tag="ACF4ZO_001193"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1025..1027,aa:Leu,seq:caa)
     gene            1932..2773
                     /gene="ispE"
                     /locus_tag="ACF4ZO_001194"
                     /pseudo
     CDS             1932..2773
                     /gene="ispE"
                     /locus_tag="ACF4ZO_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514767.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0050515 - 4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase activity
                     [Evidence IEA];
                     GO_process: GO:0016114 - terpenoid biosynthetic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
     gene            2842..3285
                     /locus_tag="ACF4ZO_001195"
     CDS             2842..3285
                     /locus_tag="ACF4ZO_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent MarR family transcriptional
                     regulator"
                     /protein_id="HFD5486732.1"
                     /translation="MGTLEKKLDNLVNTILLKAENQHELLFGACQSDVKLTNTQEHIL
                     MLLSQQRLTNTDLAKALNISQAAVTKAIKSLVKQDMLAGTKDTVDARVTYFELTELAK
                     PIASEHTHHHDETLNVYNRLLQKFSAKELEIVDKFVTVFAEELEG"
     gene            3289..4008
                     /locus_tag="ACF4ZO_001196"
     CDS             3289..4008
                     /locus_tag="ACF4ZO_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HFD5486733.1"
                     /translation="MRYISVENLSFQYESEPVLEGITYHLDSGEFVTMTGENGAAKST
                     LIKATLGILQPKAGRVTIAKKNKDGKQLRIAYLPQQVASFNAGFPSTVYEFVKSGRYP
                     RSGWFRHLNKHDEEHVQASLEAVGMWENRHKRIGSLSGGQKQRVVIARMFASDPDIFV
                     LDEPTTGMDSGTTDTFYELMHHSAHQHGKSVLMITHDPEEVKAYADRNIHLVRNQKLP
                     WRCFNIHEAETDDEKGGHGHA"
     gene            4001..4816
                     /locus_tag="ACF4ZO_001197"
     CDS             4001..4816
                     /locus_tag="ACF4ZO_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HFD5486734.1"
                     /translation="MLDILSYDFMQRAVMAVVAISIFAPILGIFLILRRQSLMSDTLS
                     HVSLAGVALGVVIGISPTITTIIVVVLAAILLEYLRVVYKHYMEISTAILMSLGLALS
                     LIIMSKSHSSSSMSLEQYLFGSIITISMEQVVALFAIAAIILILTVLFIRPMYILTFD
                     EDTAFVDGLPVRLMSVLFNIVTGVAIALTIPAAGALLVSTIMVLPASIAMRLGKNFKT
                     VILLGIVIGFSGMLSGIFLSYFFETPASATITMIFISIFLLVSLGGMLKKRLF"
     gene            complement(4856..5230)
                     /locus_tag="ACF4ZO_001198"
     CDS             complement(4856..5230)
                     /locus_tag="ACF4ZO_001198"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HFD5486735.1"
                     /translation="MYFCHQLKANQLLTQSQYFKVVFDIDPIQKGHLLLISKDHYTSL
                     TQLPKEVRYDLIDLQAALVAKLEQHLPISGVTSVSNDKELMEEGTQFHLHLIPRLTND
                     SFWEGITINQENWDLAPFLKHL"
     gene            complement(5289..6545)
                     /gene="tyrS"
                     /locus_tag="ACF4ZO_001199"
     CDS             complement(5289..6545)
                     /gene="tyrS"
                     /locus_tag="ACF4ZO_001199"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004831 - tyrosine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006437 - tyrosyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HFD5486736.1"
                     /translation="MNIFEELKARGLVFQTTDEQALVKALTEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKETVLEWSDKIK
                     GQLSAFLDFENGDNKAELVNNYDWFSQISFIDFLRDVGKYFTVNYMMSKDSVKKRIET
                     GISYTEFAYQIMQGYDFYELNDKHNVTLQIGGSDQWGNMTAGTELLRKKADKTGHVMT
                     VPLITDSTGKKFGKSEGNAVWLDADKTSPYEMYQFWLNVMDDDAVRFLKIFTFLSLDE
                     IAEIETQFNAARHERLAQKTLAREVVTLVHGEEAYKQALNITEQLFAGNIKNLSANEL
                     KQGLSNVPNYHVQSEDSLNLVDMLVTAGISPSKRQAREDVQNGAIYINGDRVQDLDYQ
                     LSNDDKIDDQLTVIRRGKKKYAVLTY"
     gene            6649..8949
                     /gene="pbp1b"
                     /locus_tag="ACF4ZO_001200"
     CDS             6649..8949
                     /gene="pbp1b"
                     /locus_tag="ACF4ZO_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein PBP1B"
                     /protein_id="HFD5486737.1"
                     /translation="MVKWNTKQKRISHQRLGLLDLGPVLLRTLRLLSNFFYIVIFLFG
                     MMGFGMAFGYLASQIESVKVPSKESLVKQVESLTMISQMNYSDNSLISTLDTDLLRTP
                     VANDAISENIKKAIVSTEDEHFQEHKGVVPKAVFRATLASVLGFGEASGGSTLTQQLV
                     KQQVLGDDPTFKRKSKEIVYALALERYMSKDNILCDYLNVSPFGRNNKGQNIAGVEEA
                     ARGIFGVSAKDLTVPQAAFLAGLPQSPIVYSPYLSTGQLKSEKDMAYGIKRQQNVLYN
                     MYRTGVLSKKEYEDYKAYPIQKDFIQPGSAIVNNHDYLYYTVLADAKKAMYSYLIKRD
                     KVSSRDLKNDETKAAYEERALTELQQGGYTITTTINKPIYNAMQTAAAQFGGLLDDGT
                     GTVQMGNVLTDNATGAVLGFVGGRDYALNQNNHAFNTVRSPGSSIKPIIAYGPAIDQG
                     LMGSASVLSNYPTTYSSGQKIMHADSEGTAMMPLQEALNTSWNIPAFWTQKLLREKGV
                     DVENYMTKMGYKIADYSIESLPLGGGIEVSVAQQTNAYQMLSNNGLYQKQYIVDKITA
                     SDGTVVYKHENKPIRIFSAATATILQELLRGPITSGATTTFKNRLAAINPWLANADWI
                     GKTGTTENYTDVWLVLSTPKVTLGGWAGHDDNTSLAPLTGYNNNSNYLAYLANAINQA
                     DPNVIGVGQRFNLDPGVIKANVLKSTGLQPGTVNVNGRTFSVGGEMTTSLWSQKGPGA
                     MTYRFAIGGTDADYQKAWGNFGFRKN"
     gene            9213..12779
                     /gene="rpoB"
                     /locus_tag="ACF4ZO_001201"
     CDS             9213..12779
                     /gene="rpoB"
                     /locus_tag="ACF4ZO_001201"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HFD5486738.1"
                     /translation="MAGHEVRYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFQDFLDSG
                     LKEVFEDVLPISNFTDTMELEFVGYEFKEPKYTLEEARIHDASYSAPIFVTFRLVNKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELETDSKDIAYTRIDRTRKIPFTTLVRALGFSGDDEIVDIFGESDLVR
                     NTIEKDIHKNPSDSRTDEALKEIYERLRPGEPKTADSSRSLLIARFFDARRYDLAAVG
                     RYKVNKKLNIKTRLLNQIIAENLVDAETGEILVEAGTEMTRSVIESIEEHLDGDLNKF
                     VYTPNDYAVVTEPVVLQKFKVVSPIDPDRVVTIVGNANPDDKVRALTPADILAEMSYF
                     LNLAEGLGKVDDIDHLGNRRIRAVGELLANQFRIGLARMERNVRERMSVQDNDVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSFGHLNKYGFIQTPYRKVDRATGRVTNEIV
                     WLTADEEDEYTVAQANSKLNEDGTFAEEIVMGRHQGNNQEFSASVVDFVDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLIDPKAPYVGTGMEYQAAHDSGAAVIAQH
                     NGKVVFSDAEKVEIRRQDGSLDVYHITKFRRSNSGTAYNQRTLVKVGDIVEKGDFIAD
                     GPSMENGEMALGQNPVVAYMTWEGYNFEDAVIMSERLVKEDVYTSVHLEEFESETRDT
                     KLGPEEITREIPNVGEEALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGGDGIVRDVKIFTRANGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARNLGIHIATPVFDGASSEDLWDTVREAGMDSDAKTVLYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDVTGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDN
                     EVELRDLDEGEDDDIMHVDDLEKAREKQAQETQEVSETTDEK"
     gene            12870..16511
                     /gene="rpoC"
                     /locus_tag="ACF4ZO_001202"
     CDS             12870..16511
                     /gene="rpoC"
                     /locus_tag="ACF4ZO_001202"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020904830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HFD5486739.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRAKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEPKSLLTEREYREKLQ
                     EYGHGSFVAKMGAEAIQALLKRVDLAAEIAELKEELKSASGQKRIKAVRRLDVLDAFN
                     KSGNKPEWMVLNILPVIPPDLRPMVQLDGGRFAASDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVAKEYAGNVKAAKRMVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARLLMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEDA
                     GREGEGMIFKDKDEAVMAYRNGYAHLHSRVGIAVDSMPNKPWKDNQRHKIMVTTVGKI
                     LFNDIMPEDLPYLQEPNNANLTEGTPDKYFLEPGQDIQEVIDGLEINVPFKKKNLGNI
                     IAETFKRFRTTETSAFLDRLKDLGYYHSTLAGLTVGIADIPVIDNKAEIIDAAHHRVE
                     EINKAFRRGLMTDDDRYVAVTTTWREAKEALEKRLIETQNPKNPIVMMMDSGARGNIS
                     NFSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADS
                     GYLTRRLVDVAQDVIIREDDCGTDRGLLIRAITDGKEVTETLEERLQGRYTRKSVKHP
                     ETGEVLIGADQLITEDMARKIVDAGVEEVTIRSVFTCATRHGVCRHCYGINLATGDAV
                     EVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRIQEIFEARNPKGEAV
                     ITEVKGNVVEIEEDASTRTKKVYVQGKTGMGEYVVPFTARMKVEVGDEVNRGAALTEG
                     SIQPKRLLEVRDTLSVETYLLAEVQKVYRSQGVEIGDKHVEVMVRQMLRKVRVMDPGD
                     TDLLPGTLMDISDFTDANKDIVISGGIPATSRPVLMGITKASLETNSFLSAASFQETT
                     RVLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNIEPQAMNEIEVIDHTEVSA
                     EAVFTAEAE"
     gene            16663..17028
                     /locus_tag="ACF4ZO_001203"
     CDS             16663..17028
                     /locus_tag="ACF4ZO_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HFD5486740.1"
                     /translation="MYQVIKMYGDWEPWWFIDGWQDDIIDEQQFSDWQEALDYFNQEW
                     QRMKAIFPSYHSQKNLLATFWEKEDKRWCEDCDEDLQQFHSLLLLKNKDIVPSNNYIP
                     EFEQRNDSPQVAYLCKLNL"
     gene            17121..18059
                     /gene="comGA"
                     /locus_tag="ACF4ZO_001204"
     CDS             17121..18059
                     /gene="comGA"
                     /locus_tag="ACF4ZO_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus ATPase ComGA"
                     /protein_id="HFD5486741.1"
                     /translation="MVQVLAKAILAKAEQVQAQDIYILPRADQYDLFLRIGDERRLVD
                     VYQSDRMAPLISHFKFVAGMIVGEKRRCQVGSCDYKLSKDKQLSLRLSSVGDYRGQES
                     LVIRLLHHQNKSVHYWFDGLTKVANQVGGRGLYLFAGPVGSGKTTLMYQLISNYHQEA
                     QVISIEDPVEIKNHQILQLQVNDDIGMTYDNLIKLSLRHRPDILVIGEIRDSQTARAV
                     IRASLTGAMVFSTVHAKSISGVYARLLELGVTKAELSNCLALIAYQRLLNGGALIDST
                     QNEFEYYSSSNWNQQIDQLLEAGHLNPKQAKLEKII"
     gene            17995..19029
                     /gene="comGB"
                     /locus_tag="ACF4ZO_001205"
     CDS             17995..19029
                     /gene="comGB"
                     /locus_tag="ACF4ZO_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus assembly protein ComGB"
                     /protein_id="HFD5486742.1"
                     /translation="MISFLRQDISIPSKLSLKKLSSKHQHKFIQLLANLLSTGFSFAE
                     VIAFLKRSQLLQLDYVLKMEESLLKGQGLADMLSGLGFSDAILTQISLADRHGNIETT
                     LVAIQHYLNQMARIRRKTVEVITYPLILLLFLFVMMLGLRRYLVPQLETQNQITYFLN
                     HFPAFFIGFCSGLILLFGMVWLRWRSQSRLKLYSRLSRYPFLGRLLKQYLTSYYAREW
                     GTLIGQGLDLMTILDIMAIEKSSLMKELAEDIRMSLLEGQAFHIKVATYPFFKKELSL
                     MIEYGEIKSKLGAELEIYAQESWEQFFSQLYQVTQLIQPAIFLVVAVTIVMIYAAILL
                     PIYQNMGGIF"
     gene            19031..19357
                     /gene="comGC"
                     /locus_tag="ACF4ZO_001206"
     CDS             19031..19357
                     /gene="comGC"
                     /locus_tag="ACF4ZO_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030420 - establishment of competence for
                     transformation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus major pilin ComGC"
                     /protein_id="HFD5486743.1"
                     /translation="MINQWNNLRHKKLKGFTLLEMLLVILVISVLMLLFVPNLSKQKD
                     RVTETGNAAVVKLVENQAELYELSQGSKPSLSQLKADGSITEKQEKAYQDYYDKHKNE
                     KARLSN"
     gene            19332..19760
                     /gene="comGD"
                     /locus_tag="ACF4ZO_001207"
     CDS             19332..19760
                     /gene="comGD"
                     /locus_tag="ACF4ZO_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGD"
                     /protein_id="HFD5486744.1"
                     /translation="MKKPVLAIKAFTLLETLLSLSVMSFIILGLSVPVTKSYQKVEEH
                     LFFSHFEHLYRHQQKLAILQQKQRVLDISSTKIVTEGNNLTVPKSITVNHPYRLVIDQ
                     MGGNHSLAKIIFDMTDRRFKYQFYLGSGNYQKTSQSLHSP"
     gene            19717..20001
                     /gene="comGE"
                     /locus_tag="ACF4ZO_001208"
     CDS             19717..20001
                     /gene="comGE"
                     /locus_tag="ACF4ZO_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGE"
                     /protein_id="HFD5486745.1"
                     /translation="MGIIKKQVKAYIALESMIATGILFSIVILVLSSLQQSQAALTYY
                     RKQQEKLNLALMAVQTRTKEMTLNGCHITILRTDTYISIHDDEGEVMKIE"
     gene            19994..20428
                     /gene="comGF"
                     /locus_tag="ACF4ZO_001209"
     CDS             19994..20428
                     /gene="comGF"
                     /locus_tag="ACF4ZO_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGF"
                     /protein_id="HFD5486746.1"
                     /translation="MSKQLSNIKAFTLLEALIALLVISGSLLVYQGLTQTLLKRSHYL
                     ARHDQDNWLLFSHQLREELSGARFYKVADNKLYVEKGKKVLAFGQFKSHDFRKSASNG
                     KGYQPMLFGISRSHIHIGQSQICITLKWKSGLERTFYYAFQD"
     gene            20412..20738
                     /gene="comGG"
                     /locus_tag="ACF4ZO_001210"
     CDS             20412..20738
                     /gene="comGG"
                     /locus_tag="ACF4ZO_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGG"
                     /protein_id="HFD5486747.1"
                     /translation="MPFKTNLKAGILLYAMFMASIFLLVLQVYLSQVTALHKEYQAQT
                     DYVKARLIAEIVYQDHRYKASNPVSFKGGQVICRERKERWMLIVKLDQQRQYQFEYLK
                     PKQYSQ"
     gene            20836..21789
                     /locus_tag="ACF4ZO_001211"
     CDS             20836..21789
                     /locus_tag="ACF4ZO_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFD5486748.1"
                     /translation="MTFEKIEEAYQLLLENCQLIENDLKTHIYDAIVEQNSFYLGAEG
                     ASPQVAQNSDKLKALCLTKEEWRKAYQFLFIKAAQTEQLQANHQFTPDAIGFILLYLL
                     EQLSDKDSLEVLEIGSGTGNLAQTLLNNTSKSLDYVGIELDDLLIDLSASIAEIMDSS
                     AHFVQEDAVRPQLLKESDIVISDLPVGYYPNDDIAKRYKVASSDKHTYAHHLLMEQSL
                     KYLKKDGFAIFLAPVNLLTSPQSQLLKQWLKDYAQVVALITLPDSIFGHPSNAKSIIV
                     LQKQTDHPMETFVYPIRDLKLAENIHDFMENFKKWKLSNVN"
     gene            21848..23044
                     /locus_tag="ACF4ZO_001212"
     CDS             21848..23044
                     /locus_tag="ACF4ZO_001212"
                     /EC_number="2.7.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008776 - acetate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006085 - acetyl-CoA biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HFD5486749.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEEEVLAQGIIERIGLKDSISTV
                     KYDGKKEEQILDIHDHTEAVKILLNDLIHFGIIAAYDEITGVGHRVVAGGELFKESVV
                     VNDKVLEHIEELSVLAPLHNPGAAAGIRAFRDILPDITSVCVFDTSFHTSMAKHTYLY
                     PIPQKYYTDYKVRKYGAHGTSHKYVAQEAAKMLGRPLEELKLITAHIGNGVSITANYH
                     GKSVDTSMGFTPLAGPMMGTRSGDIDPAIIPYLIEQDPELKDAADVVNMLNKKSGLSG
                     VSGISSDMRDIEAGLQEDNPDAVLAYNIFIDRIKKCIGQYFAVLNGADALVFTAGMGE
                     NAPLMRQDVIGGLTWFGMDIDPEKNVFGYRGDISTPESKVKVLVISTDEELCIARDVE
                     RLKNTK"
     gene            23231..23539
                     /locus_tag="ACF4ZO_001213"
     CDS             23231..23539
                     /locus_tag="ACF4ZO_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486750.1"
                     /translation="MYVFIEPNDLKDYLITIYDERNRAIRKQTQVYCFYLMIVLFVAL
                     FFFFPCLTIRDLVSYKLPLIFAYLYLIIRSLVAKKMEALGKIATNSQKPPFDTSQVLC
                     "
     gene            complement(23622..24392)
                     /gene="proC"
                     /locus_tag="ACF4ZO_001214"
     CDS             complement(23622..24392)
                     /gene="proC"
                     /locus_tag="ACF4ZO_001214"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004735 - pyrroline-5-carboxylate
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HFD5486751.1"
                     /translation="MKIGIIGVGKMASAIIKGLKQTPHELIISGSSLERSKEIAEQLT
                     LPYAMSHQDLIDQVDLVILGIKPQLFETVLKPLHFKQPIISMAAGISLQRLATFVGQD
                     LPMLRIMPNMNAQILQSSTALTGNALVSQELQARVRDLTDSFGSTFDISEKDFDTFTA
                     LAGSSPAYIYLFIEALAKAGVKNGMPKAKALEIVTQTVLASASNLKTSSQSPHDFIDA
                     ICSPGGTTIAGLMELERLGLTTTVSSAIDKTIDKAKSL"
     gene            complement(24440..25507)
                     /gene="pepA"
                     /locus_tag="ACF4ZO_001215"
     CDS             complement(24440..25507)
                     /gene="pepA"
                     /locus_tag="ACF4ZO_001215"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HFD5486752.1"
                     /translation="MTDLFSKIKEVTELDGIAGYEHSVRDYLRTKITPLVDRVETDGL
                     GGIFGIRDSKVEKAPRILVAAHMDEVGFMVSDIKVDGTLRVVGIGGWNPLVVSSQRFT
                     LYTRTGQVIPLISGSVPPHFLRGANGSASLPHIEDIVFDGGFTDKAEAERFGITPGDI
                     IVPQSETILTANQKNIISKAWDNRYGVLMITEMLEALKGQDLNNTLIAGANVQEEVGL
                     RGAHVSTTKFDPELFFAVDCSPAGDIYGNSGTIGDGTLLRFYDPGHVMLKDMRDFLLT
                     TAEEAGVNIQYYCGKGGTDAGAAHLQNGGVPSTTIGVCARYIHSHQTLYAMDDFVEAQ
                     AFLQAIIKKLDRSTVDLIKCY"
BASE COUNT         7631 a         4749 c         5699 g         7860 t
ORIGIN      
        1 gcaagatatg cgttggcacc cttagctcaa ctggatagag tacctgacta cgaatcaggc
       61 ggttagaggt tcgactcctc tagggtgcat cagttcggga agtagctcag cttggtagag
      121 tacttggttt gggaccaagg tgtcgcaggt tcgaatcctg tcttcccgat taatggcggt
      181 gtagctcagc tggctagagc gtccggttca tacccgggag gtcgggggtt cgatcccctt
      241 cgccgctatt atttttatgg atgacttggg acctttagct caactggtta gagcactcgg
      301 ctcataaccg agcggtcgta ggttcgagtc ctacaaggtc catatcatag ataatcatta
      361 ttttggagga ttacccaagt ccggctgaag ggaacggtct tgaaaaccgt caggcgtgta
      421 aaagcgtgcg tgggttcgaa tcccacatcc tccttttaac tatcgcggga tggagcagtt
      481 aggtagctcg tcgggctcat aacccgaagg tcgtaggttc aaatcctgct cccgcaatac
      541 ataagtatgt agttgttggc tcggtagctc agttggtaga gcaatggatt gaagctccat
      601 gtgtcggcgg ttcgattccg tctcgcgcca ttaaaattta atattttacg gaaagatagc
      661 gaagaggcta aacgcggcgg actgtaaatc cgctccttcg ggttcggggg ttcgaatccc
      721 tctctttcca tcctaaacgg gcatagttta aaggtagaac taaggtctcc aaaaccttca
      781 gtgtgggttc gattcctact gcccgtgtta gaaatatggc gggtgtggtg aagtggttaa
      841 cacatcagat tgtggctctg acattcgtgg gttcgattcc catcactcgc ctattttatt
      901 ggggtatagc caagcggtaa ggcaagggac tttgactccc tcatgcgttg gttcgaatcc
      961 agctacccca gtttaaattt tatatttaaa gccggcgtgg cggaattggc agacgcgctg
     1021 gactcaaaat ccagtgtccg caaggacgtg ccggttcgac cccggccgcc ggtatacttg
     1081 aaaaacaagg tttgtaaacc ttgttttttg ttttgatctt aggctgtagc tacgtagtac
     1141 aatctcttat attactgata aggtctattt aatgcgcaag atttgtggta tgatgaatat
     1201 gattgagtat tgatgcttta tgggattacc ggtaaggttt tgaaaaaggt ttgtcactac
     1261 taggtgcttt tttaactata gaaagacagt tatggattga tgtattgtaa ctaatgttgg
     1321 aggttaatgg tggttgagtt ttgagatatt tacactgata atcgggtgga aactggtcgg
     1381 gtatcgggta atggagtgtg gttcttcgtt taagcaagga gattatcgtt tggtggttca
     1441 tatttgcttg ttaaatgtta gggatgagat gctgagtcag caaggccatg aagataaagc
     1501 tgactggcta gagccttgag atgtgacgtt tggtggaagt cctttttggt gagatggcac
     1561 agcatatagt aatattagat cctgaggaag aattgggact ttcattaggc ttgactgggg
     1621 tatgacctca ctttacaatt catttcgatg atgggtttga tgatacgttt ttagttcaag
     1681 actttgtaga gttggagaat ttggttcttt atgaggaaga agtgcaggta attcgttgag
     1741 ccagtcgtga agatatttta ggtatgattg atgaaggttc gttcattcct tatctgaagt
     1801 ataaaataaa tttgtgcttt gagatggttg gtcaatataa agtccatcaa tcttagaagt
     1861 aataatcttt gaattttttc tgaggtttgt gtatatttga tagtgtactg atgtaagaag
     1921 taaggagtac tatgatggca atcaatgaga gagcttctgc aaaaatcaag ttaggccttg
     1981 atactaagaa taagcgatga gatggttacc acgatttatc gatggtcatg atgagtattg
     2041 atctgtgtga ctatgtgacg gttgaccata tagatgacaa taagattgtc tttgcctcaa
     2101 actgtccgaa aatacctatt aactaagata atgatgttta taagatagtt cagctaatga
     2161 aacatcgatt tcaagttaaa agaggagttt ccgtttactt ggaaaagcgg attcctatgt
     2221 gtgctggtat gggaggaggt tctagcgatg ctgttactat cagagcatta aatcagttat
     2281 ggctccttac tcttagccga aaagatatga tggatattgg tataccgatt ggtagtgatg
     2341 taccttattg cttgctttca ggttgtgccc aagtcactgg taaaggtgaa gtggtttgtc
     2401 gcattttggg gctgttatcg tcttgggtgg ttttggttaa accagatttt ggtatctcga
     2461 cttgaacaat ttttctagat attaattgta aaaccatttc aagagtgtct actactcatt
     2521 tggttgcggc gattgaagcg ggtaactata atgatgggat attgactgaa atgaacaatt
     2581 tgctggaaga tattttcatt gccaagcgac cctttattca aaaaataaaa gagaaaacac
     2641 tacaagctgg tgctgctact gttttgatga caggaagtgg accgactgtt tttgctttgt
     2701 gccaaaccga aaaacaaact ataatagttt aaaaggactt tgcaaggaag tttttaaggt
     2761 gagaatgttg taatattttg ttgggattgc ttctttggaa gcttcatgtt ataattaact
     2821 ggttaatgaa agaggagatt tatggggact ttagaaaaaa aacttgataa cttagtaaat
     2881 actattttat taaaagcaga aaatcagcat gagttattat ttggagcttg tcaaagtgac
     2941 gttaagctta ctaatacgca agaacatatt ttaatgttac tatctcagca acgtctcact
     3001 aatacagatt tggctaaggc attaaatatt agtcaggcgg cagtaactaa ggctatcaag
     3061 agtttggtca aacaagacat gctagcagga actaaggata cggttgatgc tagggtgact
     3121 tattttgaat taaccgagtt agctaagcct attgcatcag aacataccca tcatcatgat
     3181 gaaaccttaa atgtttacaa ccgtttatta caaaaattct ccgcgaaaga attagagatt
     3241 gtagataagt ttgtaacagt ttttgctgag gaattagaag ggtaatccat gagatacata
     3301 tcagtggaaa atctctcctt tcaatatgaa agtgagccag ttttagaagg gatcacttat
     3361 catttagata gtggagaatt tgtcaccatg accggtgaaa atggtgctgc aaagtcaacc
     3421 ttaataaaag caaccttagg aattttacaa ccaaaggctg gacgagttac tattgctaaa
     3481 aaaaataaag acggtaaaca attaaggatt gcttacttgc cgcagcaagt agctagcttt
     3541 aacgctggtt ttccatccac cgtttacgag tttgtcaaat caggtcgcta cccacgtagt
     3601 ggttggttta gacatttgaa caaacacgat gaagagcatg tgcaagcaag cttagaagca
     3661 gtcggcatgt gggaaaaccg tcataagaga attggtagtt tatcaggtgg tcaaaaacaa
     3721 cgtgtggtga ttgcccgtat gtttgcttct gaccctgata tttttgtgct agacgagcca
     3781 acaacgggaa tggatagcgg tactactgat accttttatg aactgatgca ccacagtgca
     3841 catcaacatg ggaaatccgt tctgatgatt acccatgacc cagaagaagt gaaggcttat
     3901 gctgatcgga acattcattt agtcagaaac caaaaacttc cttggcgttg tttcaacatt
     3961 catgaagctg aaacagatga cgaaaaagga ggtcatggtc atgcttgata ttttatccta
     4021 tgatttcatg caacgggcgg taatggcggt agttgccatt agtatttttg ctccgatttt
     4081 aggtattttc cttattttac gtcgtcaaag tttgatgagc gataccctta gtcatgtttc
     4141 tttggctggg gtagcgcttg gggtagtcat tggtatttca ccaaccatca ctactattat
     4201 tgttgtggtt ttagctgcta ttttgttaga atacctgcgt gtagtttaca aacactacat
     4261 ggagatttca acggcgattt tgatgtcact tggcttggcc ctatctctga ttattatgag
     4321 taagtcgcat agttcatcaa gcatgagttt agaacaatac ctttttggat cgatcatcac
     4381 gattagtatg gaacaagttg tcgccttgtt tgctattgct gcgattattt taatcttgac
     4441 cgttctcttc attagaccga tgtacattct gacctttgat gaagatactg cttttgtaga
     4501 tggtctgccc gttcgcttga tgtctgttct attcaatatc gtcaccgggg ttgctattgc
     4561 tttgaccatt ccagcagcag gagcactttt ggtttctacc attatggtct tgccagcaag
     4621 tatcgcaatg agattgggta aaaattttaa aacagttatc ttactgggaa ttgtcatcgg
     4681 ttttagcggt atgttatctg gtattttctt atcttatttc tttgaaacgc cagctagtgc
     4741 cactattacc atgattttca ttagtatttt cctcttagtt agtctaggtg gaatgcttaa
     4801 aaaacggtta ttttaataag aaaaatcctc acatgtttaa catgtgagga tttatttata
     4861 aatgctttaa aaagggggca aggtcccaat tttcttgatt aatggtgatg ccctcccaaa
     4921 agctatcatt agttaaacga ggaatcaaat gaaggtgaaa ctgagtcccc tcctccatca
     4981 actccttgtc attgctgacg ctagtgacgc ctgaaatggg aaggtgctgc tctagcttag
     5041 caactagagc ggcttgtaag tcgatgagat catagcgcac ttcctttggt agttgtgtta
     5101 gactagtgta atggtctttg gaaatcagta aaaggtgccc cttttggata ggatcaatat
     5161 caaaaacaac cttgaaatat tgactttgag tcagtagctg atttgctttg agctgatggc
     5221 aaaaatacat tctgtcatag gtacatctcc ttatgaaaaa acgagccaga gctcgtttaa
     5281 tcggttatct agtaagtgag aacagcgtat tttttcttac cgcggcgaat aacggttaat
     5341 tgatcatcaa ttttatcatc attacttaat tggtaatcta aatcttgaac gcggtctccg
     5401 ttaatgtaga ttgctccatt ttgcacgtct tcacgcgctt ggcgttttga tggggaaata
     5461 cctgcggtga caagcatgtc aacaaggtta aggctgtctt ctgattgaac gtgataattt
     5521 ggtacattgc tcaatccttg ttttaattca ttagcagaaa gatttttgat gtttccagca
     5581 aataactgct cggtaatgtt aagagcttgt ttataagctt cttcgccatg aaccaaggta
     5641 accacttcgc gtgccaaggt tttttgagcg agacgctcgt gacgagcggc attaaattga
     5701 gtttcaattt ctgcaatctc atctagagat aagaaggtga agattttcaa gaaacgcact
     5761 gcatcatcat ccatgacatt taaccagaat tggtacatct cgtaaggaga cgtcttatcg
     5821 gcatcaagcc agacagcatt accttctgat ttaccgaatt ttttcccggt tgagtcagtg
     5881 atgagtggta cagtcatgac gtgcccagtt ttatcagcct ttttgcggag caattcagta
     5941 ccagctgtca tattacccca ctggtcagag ccgccaattt gtaaggttac attatgcttg
     6001 tcattgagtt cgtagaagtc gtagccctgc atgatttggt aagcaaactc agtgtaagaa
     6061 atgcctgttt caatgcgttt tttaacagag tctttactca tcatgtagtt aacggtgaag
     6121 tatttaccga catcacggag gaagtcaata aagctgattt gcgagaacca gtcgtagttg
     6181 ttgacaagct ctgctttatt atcaccattt tcaaaatcaa ggaaagcaga caactgccct
     6241 ttaatcttgt cactccactc caaaactgtt tctttggttt gaaggctgcg ctctgcatct
     6301 ttaaaggaag gatcaccaat taaacctgtg gcaccaccca caagagcgta aggtttgtgc
     6361 cctgctagtt gcaagcgacg agatgttaag atagccacta gatggcccag atgaaggctg
     6421 tcagcggttg gatcataacc ggtataatag gatacttgcc cttctgttaa tgctttgaca
     6481 agggcttgtt catcagtcgt ttgaaagacc aagccacgag ctttgagttc ttcaaaaata
     6541 ttcataggct ttctccattt tcattatagt ttcgaatcat tatatcaaaa aacgctactg
     6601 ctatgcaagc tttatcaaag tttggtataa tgatagatga ggtattttat ggtgaaatgg
     6661 aacacgaaac aaaagcgtat aagtcatcaa agattaggtc tcttggattt ggggccggtg
     6721 ctattacgta cgttgagact actgtctaac tttttttata ttgttatctt cctttttgga
     6781 atgatgggat ttggtatggc atttgggtat ttggctagtc agattgaatc tgttaaggta
     6841 ccaagtaaag aaagtttagt caaacaagtt gaatcattaa cgatgatttc gcaaatgaac
     6901 tattctgata atagtttaat ttctacttta gatacggatt tacttcgaac accagtagct
     6961 aatgatgcga tttcagagaa tatcaaaaaa gctattgtat caacagaaga cgaacatttt
     7021 caagaacata aaggtgtcgt gccaaaagct gtttttcggg caacattggc ttctgtattg
     7081 ggatttggag aagctagtgg aggttcgacc ttaacacagc aattggtcaa gcaacaagtt
     7141 ttgggagacg atcccacatt taagcgcaag tctaaggaga tcgtttacgc tcttgcctta
     7201 gagcgttata tgtccaaaga caatatctta tgtgattatc ttaatgtttc accttttggt
     7261 cgtaacaaca agggccaaaa tattgctggt gttgaagaag ctgcgcgtgg catttttggc
     7321 gtttctgcca aagatttaac ggtgccacag gcagcatttt tggcggggct tccgcagagt
     7381 cctattgttt attctcctta tttgtcaacg ggacaactga agtcagaaaa ggacatggct
     7441 tatggcatca agcgtcagca aaatgttctc tataacatgt accgtacagg tgttctgtct
     7501 aaaaaagaat acgaggacta taaggcttat ccgattcaaa aggattttat tcaaccggga
     7561 agtgcaatag taaataatca cgattacctt tattacacgg tgttagcgga tgctaaaaaa
     7621 gccatgtata gctatttgat taagcgagat aaggtgtcta gtcgtgattt gaaaaatgac
     7681 gaaactaaag ctgcttatga agagagagcc ttaacagaat tgcaacaggg tggctatacc
     7741 atcaccacaa ccattaataa gcctatttac aatgcgatgc agacagcggc agctcagttt
     7801 ggtggcctgt tagatgatgg cactggtaca gttcaaatgg gaaatgtctt gacagacaat
     7861 gcgactggtg ctgtgttagg ttttgttggt ggtagagatt atgctctgaa tcaaaataat
     7921 catgctttca atacagttag atcgccaggt tctagcatta aaccgataat cgcttatggt
     7981 cctgctattg atcaaggttt aatggggagt gctagcgttt tgtctaatta cccaacaact
     8041 tactcgagtg gccaaaaaat catgcatgct gatagtgaag gaacagccat gatgccactt
     8101 caagaggccc taaatacttc ttggaacatc ccagcttttt ggacacagaa attactgcgt
     8161 gaaaaagggg tcgatgtcga aaattatatg acaaaaatgg gttataagat tgcagactac
     8221 tcgattgaaa gtttacctct agggggcggt attgaagtct cggttgctca acaaaccaat
     8281 gcttaccaaa tgctttcaaa caatggctta tatcaaaagc aatatattgt agataagatt
     8341 actgctagcg atggtacagt cgtttacaaa catgaaaata agccaattcg tattttttct
     8401 gcagcaacag caacgatttt acaagaattg ttgagaggtc cgattacttc aggcgctacg
     8461 actactttca agaaccgttt ggcggctatt aatccgtggc ttgctaatgc tgattggatt
     8521 ggtaagaccg gaacaactga gaattatacg gatgtttggc tagtcctgtc tactccaaaa
     8581 gttaccttag gcggttgggc aggacatgat gacaatacct cattagcgcc attaacagga
     8641 tataacaata attctaatta ccttgcctat ttagctaatg ccattaatca ggccgatccc
     8701 aatgttattg gagtagggca acgcttcaac ttagatccag gagtcattaa ggcgaatgtc
     8761 ttgaagtcaa caggtttaca accaggaact gttaatgtca atggacgtac tttttctgtt
     8821 ggtggagaaa tgaccaccag tctatggtcc caaaaaggac cgggggctat gacttatcga
     8881 tttgctattg gtggcacgga tgccgattat caaaaagcct gggggaactt cgggttcaga
     8941 aaaaattagg ttgccattta tcgataaaaa gggtataata gcaataacta tttgtcgtcc
     9001 aatctagctg aaatattgtc cagttaggaa gaacagcagt taaatcacac tgataaagtc
     9061 agatttagct gctctttttg tgtctatttt tagaaaagat agggtttgta acctatattt
     9121 aaatattcta aaaattaaca tttagggcaa atgataactt agttgcgatt tgctgaaaca
     9181 gcaaagctta aatagaagaa ggagctaaaa acttggcagg acatgaagtt cgatacggaa
     9241 aacaccgtac acgtcgtagc ttttcaagaa tcaaagaagt tcttgattta ccaaatttga
     9301 ttgaaattca aactgactca ttccaagatt tccttgattc aggcttgaaa gaagtatttg
     9361 aagatgtact tcctatttca aactttacgg atactatgga acttgaattt gttggttacg
     9421 aatttaaaga acctaaatat acccttgaag aagctcgtat ccacgatgca agttattctg
     9481 caccaatctt tgttaccttc cgtttggtca ataaagaaac tggtgagatt aaaactcaag
     9541 aagtcttctt tggtgacttc ccaatcatga cggaaatggg tacctttatt atcaatggtg
     9601 gtgaacgtat catcgtttct cagttggtgc gttctccagg tgtttatttc aacgataaag
     9661 ttgataaaaa cggtaaagtt ggttacggat caacagtgat tcctaaccgt ggggcttggt
     9721 tggaattaga gactgactca aaagacattg cctacactcg tattgaccgt acccgtaaga
     9781 ttccattcac aaccttggtt cgtgcccttg gtttctcagg tgatgatgaa attgttgata
     9841 tctttggtga aagcgacctt gttcgtaata ccattgaaaa agacattcac aaaaatccaa
     9901 gtgattctcg tacagacgaa gcccttaaag aaatttacga gcgtcttcgt ccaggtgagc
     9961 caaaaactgc agatagctct cgtagtctct tgattgcgcg tttctttgat gcacgtcgtt
    10021 acgatttggc tgcggttggt cgttacaaag tgaacaaaaa acttaatatc aagactcgtc
    10081 ttttgaacca aatcattgct gaaaaccttg tggatgctga aactggcgaa attttggtag
    10141 aagctggaac tgagatgact cgtagcgtca tcgaatccat cgaagaacac cttgacggtg
    10201 atttgaacaa gtttgtttac acaccaaatg attacgctgt ggttactgaa cctgttgttc
    10261 ttcaaaagtt caaggttgtg tcaccaattg atcctgatcg tgtagtaact attgttggta
    10321 atgccaatcc agatgataag gttcgtgcat tgacacctgc tgatattttg gcagaaatgt
    10381 catacttctt gaaccttgct gaaggtcttg gaaaagttga cgatattgac cacttaggta
    10441 accgtcgtat ccgtgccgtt ggtgaattgc ttgccaacca attccgcatc ggtcttgctc
    10501 gtatggagcg taacgtgcgt gagcgtatgt ctgttcaaga caacgatgtg ttaacaccac
    10561 aacaaatcat caatatccgt cctgtcacag cagctgttaa agaattcttc ggttcgtctc
    10621 agttgtcaca gttcatggac caacacaacc cattgtcaga gttgtctcac aaacgtcgtt
    10681 tatctgcctt aggacctggt ggtttgacac gtgaccgtgc tggttatgag gttcgtgacg
    10741 tgcattacac gcactatggc cgtatgtgtc cgattgaaac gcctgaagga ccaaatattg
    10801 gtttgattaa caacttgtct tcatttggac atcttaataa atatggtttc attcaaacac
    10861 cttaccgtaa ggttgaccgt gcgactggta gggtaactaa cgagattgtt tggttgactg
    10921 ccgacgaaga agacgaatac acagttgcac aggccaattc gaaactaaac gaagatggca
    10981 cttttgctga agaaatcgtt atgggtcgtc accaaggtaa taaccaagaa ttttctgcaa
    11041 gtgttgttga tttcgttgac gtttccccta aacaggtagt tgctgttgcg acggcatgta
    11101 ttcctttctt ggaaaatgat gactccaacc gtgctctcat gggtgccaac atgcaacgtc
    11161 aggctgtgcc attgattgat ccaaaagcac catatgttgg tactggtatg gaatatcaag
    11221 ctgcccatga ctcaggcgct gcggtgattg ctcagcacaa tggtaaagtt gtcttttctg
    11281 atgctgaaaa agtggaaatc cgtcgtcaag atggctcact tgatgtttac cacattacca
    11341 aattccgtcg ttcaaactca ggaacagcct ataaccaacg cacccttgtt aaagtaggag
    11401 acatcgttga aaaaggtgat ttcatcgctg atgggccttc tatggaaaat ggtgaaatgg
    11461 cccttggaca aaacccagtc gttgcttaca tgacttggga aggttacaac ttcgaggatg
    11521 ctgttatcat gagtgagcgc cttgtgaaag aagatgtcta cacatctgtt cacttggaag
    11581 aattcgaatc tgaaacgcgt gatacaaaac ttggccctga agaaatcact cgggaaatcc
    11641 caaatgttgg tgaagaagcc ctcaaagacc ttgacgaaat gggaattatc cgtatcggtg
    11701 ctgaggttaa agaaggcgac atcttagtag gtaaagtcac acctaaaggt gaaaaagacc
    11761 tctctgctga agaacgttta cttcacgcca tctttgggga taaatcgcgt gaagtgcgtg
    11821 atacctcact tcgtgtccct cacggtggtg atggtatcgt tcgtgatgtg aaaatcttta
    11881 cacgcgctaa cggcgatgaa ttgcaatcag gtgttaatat gcttgtgcgt gtttacatcg
    11941 ctcaaaaacg taaaatcaag gtcggagata aaatggccgg tcgtcacgga aacaagggtg
    12001 tcgtttcacg tattgtacca gttgaagaca tgccatacct tccagacgga acaccagttg
    12061 acatcatgtt gaaccctctt ggggtgccat cacggatgaa tattggtcag gttatggaac
    12121 ttcaccttgg tatggctgct cgtaatcttg gcattcacat tgcaacacct gtctttgacg
    12181 gggcttcatc agaagacctt tgggacactg ttcgcgaagc tggtatggat agcgatgcta
    12241 agacggtcct ttatgatggt cgcaccggtg aaccatttga caaccgtgta tccgttggtg
    12301 tcatgtatat gatcaaactt caccacatgg ttgatgataa acttcatgcc cgttctgtag
    12361 gaccatactc acttgtcacc caacagccac ttggtggtaa agctcaattt ggtggacaac
    12421 gttttggtga gatggaggtt tgggcccttg aagcttatgg tgcatcaaat gttcttcaag
    12481 aaatcttgac ctacaagtca gatgacgtca caggacgttt gaaagcctat gaagcgatta
    12541 ctaaaggtaa accaattcca aaaccaggtg taccagaatc cttccgtgtt cttgtaaaag
    12601 aattgcaatc gcttggtctt gatatgcgtg tgcttgacga ggatgataat gaagtggaac
    12661 ttcgtgatct tgatgaaggt gaagacgatg acattatgca tgttgacgat ctcgagaagg
    12721 cacgtgaaaa acaagctcaa gaaacccaag aagtttctga aacaactgac gaaaaataag
    12781 caatcaattc ttattaaata attatttact ggtctggggc aaaggcccca ggaactggta
    12841 aagtcatcaa aggcagaaag gtaaaactag tggttgacgt aaatcgtttt aaaagtatgc
    12901 aaatcacatt agcctcacca agtaaggtcc gttcatggtc ttatggtgaa gttaaaaaac
    12961 ctgaaacaat caactaccgt acattaaaac cagaacgtga aggactcttt gacgaagtca
    13021 tctttggtcc aacaaaagac tgggaatgtg cgtgtggtaa gtacaaacgt atccgttata
    13081 aagggatcgt ttgtgaccgc tgtggggttg aggtaactcg tgctaaagta cgtcgtgaac
    13141 gtatgggtca cattgagtta aaagctcctg tatcacatat ctggtatttc aaagggattc
    13201 catctcgtat gggattgact cttgatatga gtcctcgtgc ccttgaagaa gtgatctatt
    13261 ttgcggctta tgtggtcatt gatccaaaag atacaccgct tgaaccaaaa tcattattaa
    13321 cagaacgtga ataccgtgaa aaactacaag agtatggtca tgggtcattt gtcgctaaga
    13381 tgggtgctga agccattcaa gctctcttga aacgtgtgga cttggcagct gaaatcgctg
    13441 aattaaaaga agagttgaaa tctgcttctg gtcaaaaacg gattaaagca gttcgtcgtt
    13501 tagacgtcct tgatgccttt aacaaatctg gaaataaacc agaatggatg gttcttaaca
    13561 tcctgccggt tattccacca gatcttcgtc cgatggttca attggatggt ggccgttttg
    13621 cggcatcaga cttgaatgac ttgtaccgtc gtgtgattaa ccgtaacaac cgtttggcac
    13681 gtttgttaga acttaatgcc cctggcatca ttgttcaaaa tgaaaaacga atgcttcaag
    13741 aagccgttga tgctttgatt gataatggtc gtcgtggtcg tccaatcact ggaccaggaa
    13801 gtcgtccatt gaaatcattg agccacatgc ttaaaggtaa acaagggcgt ttccgtcaaa
    13861 acttacttgg taaacgagta gacttctctg gacgttccgt tatcgctgtt ggtccaaccc
    13921 ttaaaatgta tcaatgtggt gtcccacgtg aaatggctat cgagcttttt aaaccatttg
    13981 taatgcgcga aattgttgcc aaagaatatg ctggtaacgt taaagccgct aaacgtatgg
    14041 ttgaacgtgg cgacgaacgc atctgggata tcttagaaga agttatcaaa gaacacccag
    14101 tcctacttaa ccgcgcaccg acccttcaca gacttggtat tcaggctttt gaaccggttc
    14161 ttattgacgg taaggcactt cgtcttcacc cacttgtgtg tgaggcctac aatgccgact
    14221 tcgatggaga ccaaatggcc atccacgtgc cactttcaga agaagcacaa gctgaagctc
    14281 gtcttttgat gcttgctgca gagcacatct tgaaccctaa agatggtaaa ccagttgtta
    14341 ccccatctca ggatatggtt cttggtaact actatcttac gatggaagat gctggtcgcg
    14401 aaggcgaagg tatgattttc aaggataaag acgaagctgt gatggcatat cgtaatggtt
    14461 atgctcatct tcatagtcgt gtgggtatcg ctgttgacag catgccaaac aaaccttgga
    14521 aagataatca aagacataaa ataatggtga caactgttgg taagattttg tttaacgaca
    14581 tcatgccaga ggaccttcct tacctccaag agccaaacaa tgccaacttg acagaaggaa
    14641 cacctgataa atacttcctt gaacctggtc aagacatcca agaagtgatt gatggcttag
    14701 aaatcaatgt gccatttaag aagaaaaacc tcggtaacat cattgcggaa accttcaaac
    14761 gtttccgtac aacagaaaca tcagccttcc ttgaccgttt gaaagacctt ggttactacc
    14821 attcaaccct tgctggtttg acagtgggta tcgctgacat tcctgttatt gataataaag
    14881 ctgaaatcat tgatgctgct caccatcgtg ttgaagaaat taacaaagcc ttccgtcgtg
    14941 gtttgatgac agatgatgac cgttatgttg ccgttacaac aacatggcgt gaagctaaag
    15001 aagcccttga aaaacgtttg attgaaacac aaaatcctaa gaacccaatc gttatgatga
    15061 tggactcagg agctcgtggt aacatctcta acttctcaca gcttgcgggt atgcgtggtt
    15121 tgatggctgc tcctaacgga cgcatcatgg aacttcctat cttgtcaaac ttccgtgaag
    15181 gtttgagcgt tttggaaatg ttcttctcaa cccacggtgc acgtaaaggg atgaccgata
    15241 cggcccttaa aacagccgac tcaggttatc ttactcgtcg tttggttgac gttgcccaag
    15301 atgttatcat tcgtgaggac gattgtggca ctgatcgtgg tcttcttatc cgtgctatta
    15361 cagatggtaa agaagttacc gaaacgcttg aagagcgtct tcaaggtcgt tacacacgta
    15421 aatcagtcaa acaccctgaa actggtgaag tcttgattgg tgctgaccaa ttaatcactg
    15481 aagacatggc tcgtaagatt gttgatgcgg gtgttgaaga agtgaccatt cgttctgtct
    15541 ttacctgtgc gactcgtcat ggtgtctgcc gtcactgtta tggtatcaac cttgcaactg
    15601 gtgatgctgt tgaagtgggt gaagcagttg gtactattgc tgcccaatct atcggtgagc
    15661 ctggtactca gcttaccatg cgtaccttcc acacgggtgg tgtagcctca aataccgata
    15721 tcacacaggg tcttcctcgt attcaagaga tctttgaagc acgtaatcct aaaggggaag
    15781 cggtcattac tgaagtgaaa gggaatgtcg tcgagattga agaagatgcg tcaactcgta
    15841 ccaagaaagt ctacgttcaa ggtaaaactg gcatgggcga atatgtcgta ccatttacag
    15901 cacgtatgaa agttgaagtt ggcgacgaag ttaatcgcgg agctgctctt acagaagggt
    15961 caattcaacc gaaacgtctc cttgaagtgc gtgatacctt gtcagttgaa acgtaccttc
    16021 ttgcagaagt acaaaaagtt taccgtagcc aaggggtaga aatcggagac aaacacgttg
    16081 aggtaatggt tcgccaaatg cttcgtaaag ttcgtgtcat ggatccaggt gatacagacc
    16141 tccttccagg tacacttatg gatatttctg atttcacaga tgctaacaaa gatattgtta
    16201 tctctggtgg tatccctgcg acatctcgtc cagttcttat gggtattact aaggcttccc
    16261 ttgaaaccaa ttccttctta tcagctgcat ccttccaaga aacaactcgt gttcttacag
    16321 atgctgctat ccgtggtaag aaagaccact tacttggtct taaagaaaat gttatcattg
    16381 gtaaaatcat cccagctggt actggtatgg ctcgttaccg taacatcgaa ccacaagcga
    16441 tgaatgagat tgaagtgatt gatcatacag aagtctcagc agaagccgtt tttacagcag
    16501 aagcagaata atctcatgaa agagtcctta ggggctcttt tttgtctgag tttgttggca
    16561 gtaaaaagca ttgacaatca gtcttagtcc caatgagcag atgtttttca aaatacttat
    16621 gatttagcta taataatgca taagaggaat gggtaatgtg ttatgtatca agtaattaaa
    16681 atgtatggtg attgggagcc ttggtggttc atcgatggat ggcaagacga tattatagat
    16741 gagcaacaat ttagtgactg gcaagaagcg cttgattatt ttaatcaaga atggcagcgc
    16801 atgaaagcta tttttcctag ttatcatagc caaaagaatt tgttagctac tttttgggaa
    16861 aaagaagata aaagatggtg cgaggactgt gacgaagatt tgcagcagtt tcattctctt
    16921 ttactcctta aaaataaaga tattgtacca agcaataatt atatccctga atttgaacaa
    16981 cgaaatgatt caccacaggt agcttatctt tgcaagttaa acctttaagt gtttattaaa
    17041 aacaaaataa gttaaaagaa aatatcactt cttctgatat tttctttttt tgtttacgaa
    17101 taaatgagta aggaggaatt atggtacaag tattagcaaa agctattcta gcaaaagctg
    17161 aacaggttca ggcacaagat atttatattt tgccaagagc agatcaatat gatctttttt
    17221 tacgaatagg agatgaaagg agattagttg atgtttatca gagcgatcgg atggctcctc
    17281 ttattagtca ctttaaattc gttgcaggaa tgatagttgg tgaaaagaga cgttgtcagg
    17341 tgggttcatg tgattataag cttagtaaag ataagcagtt atctttgcgc ttatctagcg
    17401 tgggtgatta tcgcgggcaa gaaagcttag tgattcgtct gcttcatcat caaaataaaa
    17461 gtgtacatta ttggtttgat ggattgacaa aagtagccaa tcaggttggc ggtagagggt
    17521 tgtatttatt tgcaggacca gttgggtctg ggaagacaac cttgatgtac cagctgattt
    17581 cgaattatca tcaagaagca caggttatta gtatagaaga tcctgtagaa attaaaaatc
    17641 accagatttt acaattacaa gtgaatgatg atattggtat gacttatgac aatttgatca
    17701 aactgtcttt acgccatcga ccagatattt tagttattgg tgagattcga gatagtcaaa
    17761 cagcaagagc cgttattagg gctagtctaa caggtgccat ggttttttca acggttcacg
    17821 ctaaaagtat ctcgggtgtt tatgcaagat tgttagaact tggtgtaacg aaagcagaac
    17881 tgtctaattg cttagcatta attgcttacc aaaggttact taatggagga gcattgattg
    17941 actctactca aaacgaattt gaatattatt cctcatcgaa ctggaatcaa caaattgatc
    18001 agcttcttga ggcaggacat ctcaatccca agcaagctaa gcttgaaaaa attatctagt
    18061 aaacatcagc ataaattcat tcaattacta gctaatcttt tatctacagg atttagcttc
    18121 gcagaggtta ttgctttttt aaaaagaagc cagttgcttc agctagatta tgttcttaaa
    18181 atggaagagt ctttattaaa aggacaaggc ttagcagata tgttgtcggg tttaggtttt
    18241 tcagatgcta ttcttactca aattagttta gctgatagac acggtaatat tgaaacaaca
    18301 ttagtagcga ttcaacatta cttgaaccaa atggcaagga tcagacgaaa aactgttgaa
    18361 gttatcacct atcctcttat tcttttactt tttctttttg tgatgatgct agggttgaga
    18421 cgctatttag tccctcaatt agaaactcaa aatcagataa cttactttct taaccatttt
    18481 cctgccttct ttataggttt ttgctcaggt cttattttgt tgttcgggat ggtatggcta
    18541 cgatggcgat ctcaaagccg cttgaaactc tatagtcggc taagccgtta tcctttttta
    18601 ggtagactgt taaaacaata cttaactagt tattatgcta gagaatgggg tacgttaata
    18661 ggtcaaggtc ttgatttgat gactatttta gacattatgg ccattgagaa atcctcacta
    18721 atgaaagaat tagctgagga catcagaatg agtctgcttg aagggcaagc ctttcacatt
    18781 aaagtagcta cctacccttt ttttaaaaaa gaattaagtt taatgattga atacggtgaa
    18841 atcaaatcga aactgggggc cgagttggaa atctatgccc aggaaagctg ggaacaattt
    18901 tttagtcagc tttatcaagt gacacaactt attcaaccag ctattttttt agtagttgct
    18961 gtgacaatcg tcatgattta tgcggcaatc ttattaccaa tttaccaaaa tatgggaggt
    19021 attttttaag atgattaatc aatggaacaa cttacgacac aagaagctaa aaggatttac
    19081 tcttctagaa atgttattgg tgattcttgt catcagtgtt ttgatgctat tatttgtgcc
    19141 taatttaagc aagcaaaaag acagggttac agaaacaggt aatgccgctg ttgttaaatt
    19201 agtggagaat caagcagaac tatatgaatt atctcaaggc tcaaaaccaa gtttgagcca
    19261 gttaaaggca gatggtagta tcactgagaa acaagaaaaa gcttatcaag actattatga
    19321 caaacataaa aatgaaaaag cccgtcttag caattaaagc ttttactttg cttgaaactt
    19381 tactaagttt gtcagtgatg agtttcatta tattgggatt gtctgtacca gtgacaaaaa
    19441 gctatcaaaa agtagaagag catctgtttt ttagccattt tgaacatttg tatcgacatc
    19501 agcaaaagtt agccatatta cagcaaaaac agcgcgtctt ggatatttct tcaacaaaaa
    19561 ttgttacaga aggtaataac ctaacagttc ctaaatcaat aacagtgaat catccttatc
    19621 ggttagttat tgatcagatg ggaggcaacc attccttagc taaaattatt tttgacatga
    19681 ctgatcgacg ctttaaatac caattttatc tagggagtgg gaattatcaa aaaacaagtc
    19741 aaagcttaca tagcccttga aagtatgatc gcaacaggca tcctctttag tattgtcatt
    19801 ctcgtcttaa gcagtttaca gcagagtcag gctgctctaa cgtactatcg aaagcagcaa
    19861 gaaaagctta atctagcctt gatggcagta caaactagaa ctaaagagat gacattgaat
    19921 ggttgtcata ttactatttt acgtacggat acatatatta gtattcacga tgacgaagga
    19981 gaagtgatga agattgagta aacaattaag taacataaaa gcttttaccc ttctagaggc
    20041 attaatagcc ttactcgtga tatcagggtc tttattggtt tatcaaggtt tgacccaaac
    20101 cctccttaaa cgtagccatt atctagcccg tcatgatcaa gacaattggc tcttattttc
    20161 tcatcaattg cgagaggagt taagtggagc aagattttac aaagtagctg ataataaact
    20221 atacgttgaa aagggaaaga aagtactagc ttttggccaa tttaaaagtc atgatttccg
    20281 aaaatcagct agtaatggaa aagggtatca acccatgtta tttggaatat cacgtagtca
    20341 tattcacata gggcagtcac agatttgcat tactttaaag tggaaaagtg ggttagaaag
    20401 gactttttat tatgcctttc aagactaatc tcaaagcagg catccttttg tatgctatgt
    20461 ttatggctag tatttttttg ctggttttac aggtttacct ttctcaagtg acagctctac
    20521 acaaggaata ccaagctcaa actgactatg ttaaagcccg actgatagca gaaatagttt
    20581 atcaagatca tagatataaa gcttctaatc ctgtttcttt taaaggtggt caagtcattt
    20641 gtcgagagcg aaaagagaga tggatgttaa ttgttaagtt agatcagcaa cgacagtatc
    20701 agtttgaata ccttaaaccc aaacaatata gtcaataaat agtattgttg tcataaatcc
    20761 ttaaaatgat ccaatatata gtaattaaag gtgacacttc ttttcatttc aagtgtaatt
    20821 tggtatgata aggttatgac ttttgaaaaa attgaagaag cttatcagct gctcttagag
    20881 aattgtcaac taattgaaaa tgatctaaaa acacatatat acgatgccat tgttgaacaa
    20941 aactcctttt atttaggggc tgagggagct agtcctcaag ttgctcaaaa tagtgataaa
    21001 ctgaaagcct tgtgcctgac aaaagaagaa tggcgtaagg cctaccagtt tctttttatt
    21061 aaggcagctc agactgagca actccaagcc aaccatcagt tcacaccaga tgctattggc
    21121 ttcattctgc tgtatctttt ggaacaattg agtgataaag atagcttaga ggtacttgag
    21181 attggaagtg gaacagggaa cctagcccaa acccttctca acaacacgag caagagcctt
    21241 gattatgtag ggattgaact tgatgatctc ttgattgatc tgtcagccag tattgctgag
    21301 ataatggatt cttcagccca ttttgttcaa gaagatgcgg taaggcctca attactaaaa
    21361 gaaagtgaca ttgtcatcag tgacttacca gttggttatt atcctaacga tgatattgcc
    21421 aaacggtaca aggtggctag ttcagataag catacctatg cccatcattt attaatggaa
    21481 cagtctttaa aatacttgaa aaaagacggt tttgcgattt ttctggcacc agtcaattta
    21541 ttgacgagcc ctcagagcca gttattgaaa cagtggttaa aagattatgc tcaggtggtg
    21601 gccttaatta cgctaccaga ttctattttt ggtcatccct ctaatgctaa gtccattatt
    21661 gtcttacaaa aacaaacaga ccacccaatg gaaacctttg tctatccaat tcgggatttg
    21721 aagcttgcag agaatattca tgattttatg gaaaatttca aaaaatggaa actgagtaat
    21781 gtcaattaat tgattttttg ttataataaa aaagcatcac agaaaacgat ttcaagagag
    21841 gttaaaaatg tcaaagacaa ttgcaattaa tgcaggtagt tctagtttaa aatggcaact
    21901 ttatcagatg ccagaagaag aagtgttagc acaaggaatt attgagcgta ttggtctcaa
    21961 ggattctatt tcaacagtta agtacgatgg caaaaaagaa gagcaaattc ttgatattca
    22021 cgatcataca gaagctgtta aaatcttatt gaacgatttg attcactttg gaatcattgc
    22081 agcttatgat gaaattacag gagttggaca ccgtgttgtt gctggtggtg aacttttcaa
    22141 agaatccgtt gtggttaatg acaaagttct tgaacatatt gaagaattat ccgttttagc
    22201 tccacttcac aatcctggag cggcggcagg gattcgtgcc ttccgtgata ttttgccaga
    22261 tattaccagt gtttgtgtgt ttgacacgtc atttcacact agcatggcaa agcatactta
    22321 cctttaccca attcctcaaa aatattatac ggactacaag gttcgtaaat atggggcgca
    22381 tgggacaagt cataaatatg tagcgcaaga agctgctaaa atgcttggtc gtccattaga
    22441 agaattaaaa ctaattactg ctcatattgg aaatggtgtc tcaattacag ctaattacca
    22501 cggtaaatca gttgatacct caatgggatt cactccatta gctggtccta tgatgggaac
    22561 acgttctggt gacattgacc cagctatcat tccttattta attgagcaag acccagaatt
    22621 aaaagacgct gctgacgttg ttaatatgtt aaacaaaaaa tcaggtctta gtggggtgtc
    22681 aggcatttct agtgatatgc gtgatatcga ggctggttta caagaagata atccagatgc
    22741 tgttttagct tacaatatct ttattgatcg cattaaaaaa tgcattggtc aatattttgc
    22801 tgttttgaat ggggcagatg ctttggtctt tacagctggt atgggtgaaa atgcaccatt
    22861 gatgcgtcaa gatgttattg gtggcttaac atggttcgga atggacattg atcctgagaa
    22921 aaatgttttt ggataccgtg gtgatatttc aacaccggag tcaaaagtga aggttcttgt
    22981 tatctcaaca gacgaggaat tgtgcatcgc gcgtgacgtt gagcgtttga aaaatacaaa
    23041 ataaaagaga ctaagttttc atagattaac caagtaaggc aacactttac ttggtttttt
    23101 atgaggttta tctgttagtt atggtgccta ggtattagtt ctgatcagtc tccttgcttt
    23161 ttgtaatctt gtgctaggcg atttggatgt cagccttatt tagaagtttt taattgcttc
    23221 aacgcttttc ttgtatgtgt ttatagagcc caatgatcta aaagactatt tgataacgat
    23281 ttatgatgag cgtaatcgtg cgattcgaaa acagacacaa gtttactgct tttacctgat
    23341 gattgttcta tttgttgcct tattcttttt cttcccttgc ttaaccattc gagaccttgt
    23401 ttcttataag ctacctttga tttttgctta cctttacttg attatcagaa gtctggtggc
    23461 taagaaaatg gaggcactag ggaaaatagc aactaatagt caaaaacctc cgtttgatac
    23521 gagtcaggtt ctttgttaga tgacttgtct aacggttgag tttcctgtct ggtcaacgga
    23581 ggtgtttgta ttgttgtctg atttgtattg gggcacttat tttacaagct tttagcctta
    23641 tcgatggttt tgtcaatagc agagctgaca gtagttgtga ggccaaggcg ttctaactcc
    23701 atcagaccag caatagttgt gccaccgggg ctacaaatag cgtcaatgaa atcgtgcgga
    23761 ctttgagaac tggtcttgag attgctggcg ctagccaaga ctgtttgagt aacaatctcc
    23821 agcgcctttg ctttaggcat gccattcttg acaccagcct tagccaaagc ctcaataaag
    23881 agataaatat aggcaggact tgaccctgct aaagcggtaa aggtgtcaaa atccttttca
    23941 ctaatatcaa atgtgctacc aaagctatct gttaagtctc gaacacgtgc ttgtaattcc
    24001 tgggacacca aagcatttcc cgtcaaagcg gtactgcttt ggagaatttg tgcattcatg
    24061 tttggcatga tacgtaacat cggaaggtct tgtcctacga atgttgctag tcgttgaagg
    24121 gaaatgcctg ctgccataga tataataggc tgtttgaagt gaagcggttt gagtaccgtt
    24181 tcaaatagtt gaggcttgat gcctaaaata acaagatcaa cctggtcaat aaggtcttgg
    24241 tgggacatag cataaggcag tgttaactgc tccgcaattt ccttggaccg ttctaaagat
    24301 gatcctgaaa tgataagttc atggggtgtt tgtttaaggc ctttgatgat agcgctagcc
    24361 attttgccaa caccaataat gccaattttc attctgttgc tccttgtggg atattatggt
    24421 taatcaggct aatgctagtt tagtaacatt taatcaagtc aacggttgag cgatccagtt
    24481 ttttgataat ggcttgtaag aaggcttggg cttctacgaa atcatccata gcgtagaggg
    24541 tttgatgaga gtgaatgtag cgtgcacaga ctccgatggt tgttgatggg acaccaccat
    24601 tttgaagatg tgcagcacct gcatctgtgc ctcccttgcc acaatagtat tggatattga
    24661 caccagcttc ctcagccgtt gtgagtaaga agtcacgcat atccttgagc atgacatggc
    24721 ctgggtcgta gaaacgcaat aaggtaccat ctccgattgt tccagaattg ccataaatat
    24781 caccagcagg cgaacaatct actgcgaaaa agagttcagg gtcgaacttg gtggttgaga
    24841 cgtgggctcc gcgcagacca acttcttctt gaacgttagc acctgcaatt agggtgttgt
    24901 taaggtcttg tccttttaac gcttcaagca tttctgttat catgagaacg ccatagcgat
    24961 tgtcccaagc ttttgaaata atattttttt gattggctgt taggatcgtt tcagattgag
    25021 ggacaataat atcacccggt gtaataccaa atctttcagc ttctgcctta tccgtaaagc
    25081 caccatcaaa cacaatatct tcgatatgtg gtagactagc agagccattt gccccacgta
    25141 aaaaatgggg aggtaccgat cctgaaataa ggggaataac ttggccagtg cgtgtgtaaa
    25201 gggtaaaccg ttgtgaactg acaacaagtg ggttccaacc accgatacca accacgcgta
    25261 gcgttccgtc aactttgata tcactgacca taaaaccgac ttcgtccatg tgcgcagcta
    25321 ctaaaatacg gggggctttt tcaactttac tatctctgat accaaaaatg ccaccaagcc
    25381 cgtctgtttc aacacggtca accagcgggg ttattttggt gcgtaggtag tcacgaacgc
    25441 tatgttcata gcccgcaatg ccatccagtt cggtaacttc tttgattttt gagaataagt
    25501 ctgtcatttt tcatctccat ttaaaaggtt tcagaccagt tcaacgcggt catctcctta
    25561 tattctacca ctttttaagt aagaatgggt ttcacagaaa agaaaaatcc cagagactag
    25621 agatctctgg aagaagtgtt tgtcttttgg cgataacctg tttttttagg cagcaaggaa
    25681 atcattaaaa tgataaagca caagctggtt aataagaata gtagggcgct taggatgcga
    25741 aaagactctt cactagcgaa aagtaaggat aatggagtca taaggagaac cttccatttt
    25801 aggttaatca gtgattttta tagcgtggtt aaattaataa taaaccacac ctaataaacg
    25861 tacctttagt ttagttgttt ttactatttt tgtcaataca taacagtaga aatctttagt
    25921 tttcttattt cagatcgtc
//
LOCUS       DAXMQE010000024        24896 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.024, whole genome shotgun sequence.
ACCESSION   DAXMQE010000024 DAXMQE010000000
VERSION     DAXMQE010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24896)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24896)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24896
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.024"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            complement(<1..1575)
                     /locus_tag="ACF4ZO_001216"
     CDS             complement(<1..1575)
                     /locus_tag="ACF4ZO_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase family protein"
                     /protein_id="HFD5486753.1"
                     /translation="MRYSRRYPSQTRQMLLALLLMTASLQAGAMTTYADEVNTNHQPL
                     TAQVEASKPTAMESVTSPADQTHPISTQEASSPLHPLTTEATPAAQESPITLEDYKAA
                     SASQLAEWARQQRVTGQQLLDFALETIKETNPELNNVISLREPLARQESEQMTDEGQP
                     FYKVPILVKGLGHTVAGSSNTNGLAFLKDKTSSSTSAFVKQLQKAGFIVVGQSSFPEM
                     GWINVTNSNLYGNTHNPWQLDQNPGGSSGGSAAAVASGQVSLASASDGGGSTRIPASW
                     SGLIGLHPTRGILEGNPTSERSNVSHFALTKSMEDTEKLFQFLLKDKAKAQQNPQRLD
                     TSIPIAYSTQTPAGTPISEEAIAAIKEAVAFLQEQGYQTVEVPYPVDGKLMMQYYYTI
                     AASAAPSINFMAQQTLKRPLQKEDVELLSWALYQTGKDLTKEDVNKAWEGIAAMTEQL
                     NQFYQKYPIFLTPTTAYPAPAADYHHIPKDLVAQLSDMSGLSKEEKLDLIYRQWLPAW
                     TLTPFTQLANLTGTPSL"
     gene            1748..2218
                     /locus_tag="ACF4ZO_001217"
     CDS             1748..2218
                     /locus_tag="ACF4ZO_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HFD5486754.1"
                     /translation="MVKYGFLSVLEEEMDKHFQYDYAMDWDKKNHAVEVTFVLEAQNK
                     EAIKTIDDSGEVTQDDIVFEDYVLFYNPAKSQFDAADYLVTIPFDAKKGFSREFLAYF
                     AQFLNDVAIEGHSDLMDFLADDSKVDFGLEWNAQAFEEGQQGLEEGESYPYPRY"
     gene            2289..3242
                     /gene="prmA"
                     /locus_tag="ACF4ZO_001218"
     CDS             2289..3242
                     /gene="prmA"
                     /locus_tag="ACF4ZO_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HFD5486755.1"
                     /translation="METWQEVTVHVHRDAQEAVSYVLIETGSQGVAIADSADYIGQKD
                     RFGELYPDVEQSDMIAITAYYPSSTNLADVIATINEQLAELASFGLQVGQVTVDSQEL
                     AEEDWADNWKKYYEPARITHDLTIVPSWTAYDASAGEKVIKLDPGMAFGTGTHPTTKM
                     SLFALEQILRGGETVIDVGTGSGVLSIASSLLGAKTIYAYDLDDVAVRVAQENIDLNQ
                     GTDNIHVAAGDLLKGVSQEADVIVANILADILVLLTDDAYRLVKKEGYLILSGIISEK
                     LDMVLEAAFSAGFFLETHMVQGEWNALVFKKTDDISGVIGG"
     gene            3242..3991
                     /locus_tag="ACF4ZO_001219"
     CDS             3242..3991
                     /locus_tag="ACF4ZO_001219"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HFD5486756.1"
                     /translation="MQQYFIKGKAEKRVTITDKDTIKHMFQVMRLTDEAEVILVFDDG
                     VKYLAKVTSSMAHELEIIEALPDQVELPVKVTVASGFPRGDKLDTIAQKVTELGANAL
                     WGYPADWSVVKWDGKKLAKKEDKLAKIVLGAAEQSKRNRVPEVHLFEHKAEFLKSLSS
                     FDHIFVAYEETAKAGQLATLAREVKEVKPGAKLLFIFGPEGGISPAEITQFEAAGAIK
                     VGLGPRIMRAETAPLYALSALSYALELQASK"
     gene            4348..6534
                     /locus_tag="ACF4ZO_001220"
     CDS             4348..6534
                     /locus_tag="ACF4ZO_001220"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015144 - carbohydrate transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIBC"
                     /protein_id="HFD5486757.1"
                     /translation="MKTSFKQLFRFEFWQKFGKCLMVVIAVMPAAGLMISIGNSIPMI
                     NHDSAFLVSLGNIIAQIGWAVIVNLHLLFALAIGGSWAKERAGGAFASGLAFVLINRI
                     TGAFYGVSSAMLADPEAKITSLLGTQMIVKDYFTSVLESPALNTGVFVGIIAGFVGAT
                     AYNKYYNYRKLPEVLTFFNGKRFVPFVVILRSIFVALILVVVWPVIQSGINSFGMWIA
                     SSQDSAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYEVMTGAAAGTKVFGQ
                     DPLWLAWVTDLVHLKGSDASAYSHLMDSVTPARFKVGQMIGATGTLMGVALAMYRNVD
                     ADKKYTYKMMFISAAAAVFLTGVTEPLEYLFMFAAMPLYIVYALVQGASFAMADLVNL
                     RVHSFGNIELLTRTPMALKAGLGMDVINFVWVSILFAVIMYFIADMMIKKMHLATAGR
                     LGNYDADILGDRNTQVTPTQVADSNSQVVQIINLLGGAGNIDDVDACMTRLRVTVKDP
                     AKVGAEDDWKKAGAMGLIQKGNGVQAVYGPKADILKSDIQDLLDSGAVIPKVNMSQLT
                     SKPTPAKDFKHVTEEVLSVADGMVLPITGVKDQVFAAKMMGDGFAVEPTNGNIYAPVA
                     GLVTSVFPTKHAFGLLTDNGLEVLVHVGLDTVALNGVPFSVKVSEGQRVHAGDLLVVA
                     DLAAIQTAERETTIVVAFTNTAEIQDVTLTSLGNQPAKTKVATVEL"
     gene            6618..7436
                     /locus_tag="ACF4ZO_001221"
     CDS             6618..7436
                     /locus_tag="ACF4ZO_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HFD5486758.1"
                     /translation="MTKVLTLNTHSWMQANTLKKLVALAEHILAEKYDIICLQEINQL
                     IESELATDLPRYQALSGTPSIHKDHFALLLIHYLQKRGQHYYWSWAYNHIGYDIYQEG
                     VAILSKQPIHVSDILVSAMADETNYHTRRSLIAKTTLDGKEVAVVNVHLSWFDKGFLG
                     EWEKLEKELLTLNCPLLLMGDFNNPTDQDGYQVMMGSPLDLQDSHKVADHVFGDHSIV
                     ADIDGWQGNKEALKVDHVFTSKDFIIRSSKTTFEGGDAPVVSDHYGLEVTLGWR"
     gene            complement(7829..8311)
                     /gene="nrdI"
                     /locus_tag="ACF4ZO_001222"
     CDS             complement(7829..8311)
                     /gene="nrdI"
                     /locus_tag="ACF4ZO_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HFD5486759.1"
                     /translation="MPQITLVFISLSGNTLSFVKRLSLYLADNYDYHVKQINIKDLKH
                     ETFPVKEEFVAILPTYLEGGNGVDSGEVEILTTPLGEFIAAHGNAQRCLGIIGSGNKN
                     FNHQYCLTAKQYAKRFGFPLLGDFELRGTPDDISRLAQLIMEASSRHSSNDTQTLPNS
                     "
     gene            8871..9428
                     /locus_tag="ACF4ZO_001223"
     CDS             8871..9428
                     /locus_tag="ACF4ZO_001223"
                     /inference="COORDINATES: protein motif:HMM:NF038330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HFD5486760.1"
                     /translation="MYDEQFWGGVSNNQFLDELYQDKLEEYTKGALTKILDLIEKGAT
                     KGEKGDPGAQGPKGEKGEKGDRGDTGAQGPVGPQGEAGQPGEKAPEKSPEVTPTPEMP
                     EQPGEKAPEKSKEVTPAPEKPADKEANQTPERRNGNMAKTPVANNHRRLPATGEQANP
                     FFTAAAVAVMTTAGVLAVTKRKENN"
     gene            9680..11899
                     /locus_tag="ACF4ZO_001224"
     CDS             9680..11899
                     /locus_tag="ACF4ZO_001224"
                     /EC_number="2.7.6.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0015970 - guanosine tetraphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HFD5486761.1"
                     /translation="MAKIMNVTGEEVIALAATYMTKTDVAFVAKALAYATAAHFYQVR
                     KSGEPYIVHPIQVAGILADLHLDAVTVACGFLHDVVEDTDITLDEIEADFGHDARDIV
                     DGVTKLGKVEYKSHEEQLAENHRKMLMAMSKDIRVILVKLADRLHNMRTLKHLRKDKQ
                     ERISRETMEIYAPLAHRLGISRIKWELEDLAFRYLNETEFYKISHMMKEKRREREALV
                     EAIVSKVKTYTTQQGLFGDVYGRPKHIYSIYRKMRDKKKRFDQIFDLIAIRCVMETQS
                     DVYAMVGYIHELWRPMPGRFKDYIAAPKANGYQSIHTTVYGPKGPIEIQIRTKDMHQV
                     AEYGVAAHWAYKKGVRGKINQAEQAVGMNWIKELVELQDASNGDAVDFVDSVKEDIFS
                     ERIYVFTPTGAVQELPKESGPIDFAYAIHTQIGEKATGAKVNGRMVPLTAKLKTGDVV
                     EIITNANSFGPSRDWVKLVKTNKARNKIRQFFKNQDKELSVNKGRDLLVSYFQEQGYV
                     ANKYLDKKRIEAILPKVSVKSEESLYAAVGFGDISPISVFNKLTEKERREEERAKAKA
                     EAEELVKGGEVKHENKDVLKVRSENGVIIQGASGLLMRIAKCCNPVPGDPIDGYITKG
                     RGIAIHRSDCHNIKSQDGYQERLIEVEWDLDNSSKDYQAEIDIYGLNRSGLLNDVLQI
                     LSNSTKSISTVNAQPTKDMKFANIHVSFGIPNLTHLTTVVEKIKAVPDVYSVKRTNG"
     gene            11914..12357
                     /gene="dtd"
                     /locus_tag="ACF4ZO_001225"
     CDS             11914..12357
                     /gene="dtd"
                     /locus_tag="ACF4ZO_001225"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacyl-tRNA deacylase"
                     /protein_id="HFD5486762.1"
                     /translation="MKLVLQRVKEASVSIDGKIAGAINQGLLLLVGVGPDDNAEDLAY
                     AVRKIVNMRIFSDADGKMNQSIQDIKGSILSVSQFTLYADTKKGNRPAFTGAAKPDLA
                     RQLYDSFNEQLAEFVPVERGVFGADMQVSLINDGPVTIILDTKCH"
     gene            complement(12455..13777)
                     /gene="ska"
                     /locus_tag="ACF4ZO_001226"
     CDS             complement(12455..13777)
                     /gene="ska"
                     /locus_tag="ACF4ZO_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptokinase"
                     /protein_id="HFD5486763.1"
                     /translation="MKNYLSIGVIALLFALTFGTVKPVQAIAGYGWLLDRPPVNNSQL
                     VVSMAGIVEGTDKKVFINFFEIDLTSQPAHGGKTEQGLSPKSKPFATNSSAMPHKLEK
                     ADLLKAIQERLIANVHSNDGYFEVIDFASDATITDRNGKVYFADKDDSVTLPTQPVQE
                     FLLRGHVRVRPYKEKPIQTPAKSVDVRYTVQFTPLNPDDDFRPVLKNTKLLKTLAIGG
                     TVTSQELLAQAQSILNESHPDYTIYERDSSIVTHDNDIFRTILPMDQEFTYHIKDREQ
                     AYGINKKSGQEEKTNNTDLISEKYYVLKKGEKPYDPFDRSHLKLFTINYVDVNTNKLL
                     KSEQLLTASERNLDFRDLYDPRDKAKLLYNNLDAFGIMDYTLTGKVEDNHDKNNRVVT
                     VYMGKRPEGENASYHLAYDKDRYTEEEREVYSYLRYTGTPIPDNPKDK"
     gene            14118..14966
                     /locus_tag="ACF4ZO_001227"
     CDS             14118..14966
                     /locus_tag="ACF4ZO_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD5486764.1"
                     /translation="MELKDYFPEMQVGPHPLGDKEWVSVKEGDQYVHFPKSCLSEKER
                     LLLEVGLGQCEVLQPLGSPWQRYLLDHQGNPPQLFETSQFIYLNHQQTLPDDLVELLQ
                     QMIAGLEVILPISATQTAFLCRQAISIKVLRWLEDLLPTLESDFGLALTMFVGNAWYQ
                     VAAGTLRECFEEECQLLTAYLRQQSGRKLLTFSGLMLWSLLSHHTFLALTRQFHQFLS
                     PQSDMADVVHALWSEHGNLVQTAQRLYIHRNSLQYKLDKFAQQSGLHLKQLDDLAFAH
                     LFLLKY"
     gene            15019..15162
                     /locus_tag="ACF4ZO_001228"
     CDS             15019..15162
                     /locus_tag="ACF4ZO_001228"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486765.1"
                     /translation="MIDRSACFGSCDRPVFTWFSCFMVPYDLTSLAIVQVAQRSLVAL
                     SLF"
     gene            15264..16397
                     /locus_tag="ACF4ZO_001229"
     CDS             15264..16397
                     /locus_tag="ACF4ZO_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD5486766.1"
                     /translation="MVELNLNHIYKKYPNTTHYAVEDFDLDIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELKIGGEVVNDKSPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYKKDDIDRRVKEAAQILGLTEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGSTTIYVTHDQTEAMTLADRIVIMSATKNPQSN
                     GTIGKIEQVGSPQELYNLPANKFVAGFIGSPAMNFFEVEVKDGRIVSEDGLAIAIPEG
                     QAKMLEAAGYKGKKVTFGIRPEDISSRQIVHDTYPSATVTAEVLVSELLGSETMLYVK
                     LGQTEFASRVDARDFHSPGEQVSLTFNVAKGHFFDRDTEQAIR"
     gene            16526..18139
                     /gene="dexB"
                     /locus_tag="ACF4ZO_001230"
     CDS             16526..18139
                     /gene="dexB"
                     /locus_tag="ACF4ZO_001230"
                     /EC_number="3.2.1.70"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043896 - glucan 1,6-alpha-glucosidase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucan 1,6-alpha-glucosidase DexB"
                     /protein_id="HFD5486767.1"
                     /translation="MKKHWWHKATIYQIYPRSFKDTNGNGIGDLKGITSQLDYLQKLG
                     ITAIWLSPVYQSPMDDNGYDISDYEAIADVFGDMADMDELLAAANERGIKIIMDLVVN
                     HTSDEHAWFVEARENPNSPERDFYIWRDEPNDLTSIFSGSAWEYDNASGQYYLHLFSK
                     RQPDLNWENEALRHKIYDMMNFWIAKGIGGFRMDVIDLIGKVPDLEITGNGPRLHDYL
                     KEMNQATFGNHDVMTVGETWGATPEIARQYSRPENKELSMVFQFEHVGLQHKPDAPKW
                     DYAEELDVPALKAIFSKWQTELKLGEGWNSLFWNNHDLPRVLSIWGNDSTYREKSAKA
                     LAILLHLMRGTPYIYQGEEIGMTNYPFKDLTEVNDIESLNYAKEAMGNGVSAARVMDS
                     IRKVGRDNARTPMQWSKDTHAGFSKAQETWLPVNPNYQDINVADALADPDSIFYTYQK
                     LIALRKEQDWLVEADYHLLPTADKVFAYQRQLGEETYVIVVNVSDEEQVFAKDLAGAQ
                     VIIANTDVDTVLETKHLQPWDAFCLKLKA"
     gene            18337..21834
                     /locus_tag="ACF4ZO_001231"
     CDS             18337..21834
                     /locus_tag="ACF4ZO_001231"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pullulanase"
                     /protein_id="HFD5486768.1"
                     /translation="MKKKVNQGSKRYQYLLKKWGIGFVIAATGTVMLGCTPSILTHQV
                     AAKTIVGLARDEAQQGDGNAKSGDGFQSSSKEAKPVLDSSSANPASIAEHHLRMHFKT
                     LPAGESLGSLGLWVWGDVDQPSKDWPNGAITMTKAKKDDYGYYLDVPLAAKHRQQVSY
                     LINNKAGENLSKDQHISLLTPRMNEVWIDENYHAHAYRPLKKGYLRINYHNQSGHYDN
                     LAVWTFKDVKTPTTDWPNGLDLSHKGPYGAYVDVPFKEGANEIGFLILDKSKTGDAIK
                     VQPKDYLFKELDNHTQVFVKDTDPKVYNNPYYIDQVSLKGAEQTTPNEIKAIFTTLDG
                     LDEDAVKQNIKITDKAGKTVAIDELTLDKDKSVMTLKGDFKAQGAVYTVTFGEVSQVA
                     RQSWQLKDKLYAYDGELGATLAKDGSVDLALWSPSADTVKVVVYDKQDQTKVLGQANL
                     TKSDKGVWRAHLTSDSIKGISDYTGYYYLYEITRGQEKVMVLDPYAKSLAAWNDATAT
                     DDIKTAKAAFIDPSKLGPTGLDFAKINNFKKREDAIIYEAHVRDFTSDKALEGKLTYP
                     FGTFSAFVEQLDYLKDLGVTHVQLLPVLSYFYANELDKSRSTAYTSSDNNYNWGYDPQ
                     HYFALSGMYSANPNDPALRIAELKNLVNEIHKRGMGVIFDVVYNHTARTYLFEDLEPN
                     YYHFMNADGTARESFGGGRLGTTHAMSRRILVDSITYLTREFKVDGFRFDMMGDHDAA
                     AIEQAFKAAKAINPNTIMIGEGWRTYQGDEGKKEIAADQDWMKATNTVGVFSDDIRNT
                     LKSGFPNEGTAAFITGGAKNLEGLFKTIKAQPSNFEADAPGDVVQYIAAHDNLTLHDV
                     IAKSINKDPKVAEEEIHKRIRLGNTMILTAQGTAFIHSGQEYGRTKQLLNPDYKTKVS
                     DDKVPNKATLIDAVAKYPYFIHDSYDSSDAVNHFDWAKATDSIAHPISNQTKAYTQGL
                     IALRRSTDAFTKATKAEVDRDVTLITQAGQDGIQQEDLIMGYQTVASNGDRYAVFVNA
                     DNKTRKVVLPQAYRYLPGAQVLADAEQAGVTAIAKPKGVQFTKEGLTIDGLTALVLKV
                     SSKTANPSQQKSQTGNHQTKTPDGSKDLDKSLMTRPKRAKTNQKLPKTGEASSKGLLA
                     AGVALLLLAISLLMKRQKD"
     gene            21949..22323
                     /locus_tag="ACF4ZO_001232"
     CDS             21949..22323
                     /locus_tag="ACF4ZO_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin domain-containing protein"
                     /protein_id="HFD5486769.1"
                     /translation="MRPKEKETSMTFEEIVANFIPSSVAEVTSAIASGKDMIVFLGRS
                     SCPYCRRFAPKLAQVATDNQKDVYFVDSENAADAAELAAFRENYQLVTVPALLVSYDQ
                     HQRAVCDSSLTPDDILAFLTRE"
     gene            22439..22804
                     /gene="yajC"
                     /locus_tag="ACF4ZO_001233"
     CDS             22439..22804
                     /gene="yajC"
                     /locus_tag="ACF4ZO_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HFD5486770.1"
                     /translation="MGFPTILMFVVMLGLIWFMQRQQKKQAQERQNQLNAIEKGDEVV
                     TIGGMFAIVDEVDTTAKKIVLDVDGVFLTFELSAIKRIVTKATTETTLVETKETIVVN
                     EPAVETVDSTDTDSAIESH"
     gene            23023..23772
                     /locus_tag="ACF4ZO_001234"
     CDS             23023..23772
                     /locus_tag="ACF4ZO_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HFD5486771.1"
                     /translation="MFGLKAKSTKKVLGSIPKHIGIIMDGNGRWAKKRLKPRVFGHKA
                     GMDALQEVTITASELGVKVLTVYAFSTENWSRPQDEVSFIMNLPVAFFDKYVPVLHEN
                     NVKIQMIGETSRLPEDTLAALNAAIDKTKRNTGLILNFALNYGGRAEITSAVRFIAQD
                     VLDAKLNPGDITEDLIANYLMTDHLPYLYRDPDLIIRTSGELRLSNFLPWQSAYSEFY
                     FTPVLWPDFKKAELLKAIADYNRRQRRFGKV"
     gene            23785..24579
                     /locus_tag="ACF4ZO_001235"
     CDS             23785..24579
                     /locus_tag="ACF4ZO_001235"
                     /EC_number="2.7.7.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002275264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004605 - phosphatidate
                     cytidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0016024 - CDP-diacylglycerol biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HFD5486772.1"
                     /translation="MKERVVWGGVAVAIFLPFLIIGNLPFQLFVGVLAMIGVSELLKM
                     KRLEVFSFEGVFAMLAAFVLAVPMDHYLTFLPIDANVAFYSLMVFFILAGTVLNSRAY
                     SFDDAAFPIATSFYVGIGFQHLINARLSGIDKVFLALFIVWATDIGAYLIGRQFGRRK
                     LLPTVSPNKTIEGSLGGIACAVLVSFIFMVIDRSVYAPHHFLTMLVLVALFSIFAQFG
                     DLVESALKRHFGVKDSGKLIPGHGGILDRFDSMIFVFPIMHLFGLF"
     gene            24652..>24896
                     /locus_tag="ACF4ZO_001236"
     CDS             24652..>24896
                     /locus_tag="ACF4ZO_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HFD5486773.1"
                     /translation="MLGIITFIIIFGILVIVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FSHVDQGGTLYTLRMLPLGGYVRMAGWGDDKTEIKTGT"
BASE COUNT         7288 a         4815 c         5778 g         7015 t
ORIGIN      
        1 caaggatggt gttcccgtca ggttagcaag ctgggtaaat ggtgttagcg tccatgcagg
       61 taaccattgc cggtaaataa ggtccaattt ttcttctttg ctcaagcctg acatgtcact
      121 gagctgtgct actaggtctt taggaatgtg gtggtaatca gcagcagggg cgggataggc
      181 tgttgtcggt gttaagaaga tggggtattt ttggtagaac tggtttaatt gctcggtcat
      241 ggctgcgata ccctcccagg ctttgttgac atcctctttg gtcaagtctt tcccagtttg
      301 gtagagcgcc catgatagga gttcgacatc ctctttttga agggggcgtt tcaaggtttg
      361 ttgtgccata aaattgatag atggcgctgc agaagcagca atagtgtaat agtattgcat
      421 catgagctta ccatcaacgg ggtaaggcac ttctacggtt tgataacctt gctcctgtaa
      481 aaaggctaca gcttctttga tcgcagcaat agcttcctca ctaattggtg ttccagctgg
      541 tgtctgggtg ctgtaagcaa tggggatact tgtgtctaaa cgctgtgggt tttgttgcgc
      601 tttagccttg tcttttaaga ggaattggaa gagcttttca gtgtcttcca tgctcttagt
      661 tagagcaaaa tggctaacat tgctacgttc agaagtcgga tttccctcta aaatgccacg
      721 tgttgggtgt aggccaatca agccactcca agaagctgga atgcgggttg aacccccacc
      781 atcagaagca ctggctagac tgacttgtcc tgaagccaca gcagctgcag agccaccaga
      841 ggacccgcca ggattttggt caagctgcca tgggttatgt gtatttccgt aaagattgga
      901 attcgtcaca ttaatccatc ccatttcagg gaaagaggac tgccctacca cgataaaacc
      961 agccttttgg agttgtttga caaaggcgct ggtagatgag ctggttttgt ctttcaaaaa
     1021 ggcaagcccg ttggtgttgc tacttccagc aacggtgtgt cctaaccctt taaccagaat
     1081 aggaaccttg taaaagggtt gcccctcatc tgtcatttgc tcgctctctt gtcgagccaa
     1141 tggttcacgc agagaaatga cattattgag ctcagggtta gtttctttga tggtttccaa
     1201 ggcaaaatct agcagctgtt ggcctgtgac ccgttgctgg cgagcccact cagctaattg
     1261 gctcgcactg gctgccttat agtcttctaa ggtaatcgga gattcttggg cggcaggagt
     1321 ggcctctgtt gttaaagggt gtaaaggaga cgaagcctct tgcgttgaga ttggatgggt
     1381 ctggtctgca ggtgaagtga cagattccat ggctgtcggc ttactagctt ccacttgggc
     1441 cgttagtggt tgatggttgg tattaacctc atccgcataa gtagtcatag ctccagcttg
     1501 taggctggca gtcattaata acaaggcaag aagcatctgt cttgtctgag aagggtagcg
     1561 tctagaatat ctcattcttt ttctcctaac atcataatcg cttattagtt taacataatg
     1621 agaggaaagt aaggggtaaa acgcttacta aaatacagaa ggcccatcag tcagcatttg
     1681 ccagtgaaag ttagctcaaa ttatgctaca atggaagcaa ataatcgtta ggaaaaagga
     1741 caattagatg gtaaaatacg gctttttatc agtattagaa gaagaaatgg ataagcattt
     1801 tcagtatgat tatgctatgg attgggacaa gaaaaatcac gcggttgaag tgacttttgt
     1861 gttagaagct caaaataaag aggccataaa aaccattgac gacagtggcg aagtgactca
     1921 agacgatatt gtctttgagg actatgtgct cttttacaac cctgccaagt ctcaatttga
     1981 tgcagcagat tatttggtta ctattccttt tgacgctaaa aagggctttt ctcgtgaatt
     2041 cttagcttac tttgcgcaat ttctcaacga tgttgctatt gaagggcaca gcgatttgat
     2101 ggatttctta gcagatgaca gcaaggttga tttcggcttg gaatggaatg cgcaagcttt
     2161 tgaagaaggt caacaaggat tagaagaagg agaaagttac ccttatccaa ggtactaagg
     2221 tgacacacga gatggtgcta acactattag gacaataacc aaaaggtcaa aatagaaagg
     2281 acatacttat ggaaacgtgg caagaagtga cggttcatgt gcatcgtgat gcgcaagagg
     2341 ctgtttcata tgtgttgatt gagacaggca gccaaggggt tgctatcgca gatagcgcag
     2401 actatattgg gcaaaaggac cgctttgggg agttataccc agatgtggag cagtctgaca
     2461 tgatagctat cacagcctat tacccaagta gcactaattt ggcggatgtt attgcgacca
     2521 ttaatgaaca gttagcggag ttagctagtt ttgggttaca ggttggtcag gttactgtgg
     2581 acagtcaaga attagctgag gaagactggg cagacaattg gaaaaaatac tatgaaccag
     2641 ctcgcatcac gcatgattta accattgtcc ctagttggac agcttatgac gcttctgctg
     2701 gggaaaaagt gattaaatta gatcctggaa tggcatttgg gacagggaca catcccacaa
     2761 ctaagatgag cctttttgct ctagaacaaa tccttcgtgg tggtgagaca gttatcgatg
     2821 tagggaccgg atcaggtgtc ctctcgattg ccagttcctt actaggtgct aaaaccatct
     2881 acgcttatga tttagatgat gtggctgttc gagtggctca agaaaacatt gatttaaacc
     2941 aaggaacaga caacattcat gtggctgctg gcgacctttt aaaaggggtt agccaagaag
     3001 cagatgtgat tgtagccaat atcttggcgg atatcttggt cttattgact gatgatgctt
     3061 accgtttggt caaaaaggaa ggttacctta tcttatcagg cattatttct gagaaattgg
     3121 atatggttct ggaagctgct tttagcgcag gcttcttcct tgagacgcat atggttcaag
     3181 gtgagtggaa tgcccttgtc tttaaaaaaa cagatgatat ctcaggagtg attggcggct
     3241 aatgcaacag tattttatta aaggcaaagc agaaaaaagg gtaacgatta ccgataaaga
     3301 taccatcaag cacatgtttc aagtgatgcg cttgactgac gaggctgaag ttatcttggt
     3361 ctttgatgat ggggtgaagt atttagccaa ggtaaccagt agtatggctc atgagttaga
     3421 gattatagag gctttgccag atcaggtgga attgcctgtt aaagtgactg ttgcttctgg
     3481 atttcctaga ggcgataagt tagatacgat tgcccagaaa gtgactgaat tgggagcaaa
     3541 tgcgctatgg gggtaccccg cagactggtc agtggtcaaa tgggatggca aaaaattagc
     3601 taaaaaagaa gacaaattgg ctaagattgt attaggagcg gctgagcaga gcaaacgaaa
     3661 tagggtgcct gaagttcacc tctttgaaca caaagcagag tttctaaaaa gcctttctag
     3721 ctttgatcat attttcgttg catacgaaga aacagccaag gcaggtcagc tagcgacctt
     3781 ggcgcgtgaa gtaaaagaag ttaaaccagg ggcaaaactc ctctttatct ttggaccaga
     3841 agggggaatt tccccagctg aaatcactca gtttgaggca gcaggtgcca tcaaggtggg
     3901 cttaggccct cgcattatgc gagcagagac agcgccgcta tatgccttaa gtgctcttag
     3961 ttatgctttg gaattgcagg catcaaaata agtaagctgt tgcttacttt agaaagaaga
     4021 ggttaaagaa acgaacaggc agttcacgat tgtgtcaacg gccttttttt attgcttctt
     4081 gtttttttga agagcgttga tgggctcatc accaaaaaag gaaatgggct cttgtcatct
     4141 ttttggagag ttacactact atttaatgaa gaaaaacgac taacatctgt ctaagaaaac
     4201 gctttacaaa ttgttgcgag gctagtataa taaaggtatc agatcaatgc aaacgattgc
     4261 atgactgagt tgtagtctat atcattgtgt cacaaaagcg ccttaagggc agctatggct
     4321 aaaaggggat aataaaggag agatagaatg aaaacatcat tcaagcaact gtttcgtttc
     4381 gaattttggc aaaaatttgg gaaatgtctt atggtcgtta ttgctgtcat gccagcggct
     4441 ggtttaatga tcagtatcgg aaactctatt ccaatgatta accacgactc agcatttttg
     4501 gtatctctag gaaacattat cgctcagatt ggctgggctg ttattgttaa ccttcacttg
     4561 ctatttgcct tggccattgg tggtagttgg gctaaagaaa gagctggagg ggcctttgcc
     4621 tcaggtcttg cttttgtctt gatcaatcgg ataacaggcg ctttttatgg cgtgtctagt
     4681 gctatgctag ctgatccaga agcaaaaatc acaagcctcc ttggcactca aatgatcgtt
     4741 aaagattatt tcaccagtgt cttggaatct ccagctttaa acacaggggt ttttgttggg
     4801 attattgcag ggttcgtagg agcaacggcc tataacaaat actataatta ccgtaaactt
     4861 cctgaagttt tgaccttctt taatgggaag cgttttgtac catttgtcgt tattttacgt
     4921 tctatttttg tagcccttat tttggttgtt gtttggccgg tgatccagtc tgggattaac
     4981 agttttggga tgtggattgc ctcttcacaa gattcagctc caatcctagc cccattccta
     5041 tatggtacct tggaacgtct cttgttacca tttggtcttc accatatgtt gacgatccca
     5101 atgaactata cagctcttgg tggaacttat gaggtcatga caggtgcagc agcggggaca
     5161 aaagtatttg gtcaagaccc tttgtggctt gcttgggtaa ctgaccttgt tcaccttaaa
     5221 ggatcagacg cttcagccta tagtcactta atggatagtg tgactccagc tcgtttcaaa
     5281 gtaggacaaa tgattggagc taccggaaca ttgatggggg ttgccttagc catgtaccgt
     5341 aatgtggatg ccgataaaaa atacacatac aaaatgatgt tcatctcagc agcggcagcg
     5401 gtctttttga caggggtaac tgagccactt gaatacctat ttatgtttgc agcaatgcca
     5461 ctttacatcg tctatgccct tgttcaagga gcttcatttg ccatggcaga ccttgtgaat
     5521 ctccgtgttc actcatttgg gaacattgag ctactaaccc gcacccctat ggctcttaaa
     5581 gcaggcctag gcatggatgt gattaacttt gtttgggttt ctatcctctt tgcagttatc
     5641 atgtacttta ttgcggatat gatgatcaag aaaatgcatc ttgcaacagc tggccgttta
     5701 ggcaactacg atgccgatat actgggtgac cgtaacactc aagtaacacc gacccaagta
     5761 gcagatagca actctcaagt cgtacaaatc attaatctcc ttggtggggc aggcaatatt
     5821 gatgatgttg atgcttgtat gacgcgctta cgagtgacgg tcaaagaccc cgctaaggtt
     5881 ggcgctgagg acgattggaa aaaagctggc gctatgggct tgatccaaaa aggcaacggc
     5941 gttcaagcgg tctatggccc taaagcagat attttgaaat cagatattca agatttgctg
     6001 gactcagggg ctgttattcc aaaagtcaat atgtcacagc tcactagcaa accgactccc
     6061 gcaaaagatt ttaaacacgt gacagaagaa gtgctatcag tggcagacgg gatggttctc
     6121 ccaatcacag gtgtgaaaga ccaggtgttt gcggctaaga tgatgggaga tgggtttgcg
     6181 gttgaaccaa caaatggcaa tatctatgca cccgtagctg gccttgtgac cagtgtcttt
     6241 ccgaccaagc atgcctttgg tttactgaca gataatggtc ttgaagtgct ggtgcacgtg
     6301 ggacttgata ccgtcgcctt aaatggtgtg cctttttcag tcaaagtctc agaagggcaa
     6361 cgggttcatg caggtgacct attagtcgta gcagatcttg ctgccatcca aacagcagag
     6421 cgtgagacaa ccattgttgt tgcttttacc aacacagcag agatccaaga tgtgaccttg
     6481 acttctttag gcaatcaacc tgctaagact aaagtagcca ccgtagaact ttaacaaaac
     6541 atcacgagat agtgataggt aatagccata gctggtttag gccctatggc tcttcttgtc
     6601 ttataaaggg aggattaatg accaaggtat taacactgaa tactcattcg tggatgcaag
     6661 ccaacactct taaaaaatta gttgctttgg ctgagcatat tttagctgaa aaatacgata
     6721 tcatttgctt gcaagaaatc aatcagttaa tcgagagcga gctggccaca gatttaccaa
     6781 gatatcaagc tctttcaggg acaccaagca ttcataaaga ccattttgct cttctcttga
     6841 tccattattt acaaaaacga gggcagcact attattggtc ttgggcttat aaccatattg
     6901 gctatgacat ttaccaggaa ggcgtagcaa tcttatcaaa acaacctatt catgtttcag
     6961 atattctcgt gtcagcgatg gctgatgaaa caaactacca taccagacgc tcactcatag
     7021 ccaaaaccac gttagatggc aaagaagtcg ctgttgtcaa tgtgcaccta tcttggtttg
     7081 acaagggttt tttaggggag tgggagaaat tagaaaaaga actgctcaca ctaaactgtc
     7141 ccttgctact tatgggagat tttaacaatc caacggatca agacggttat caagtgatga
     7201 tgggtagccc cctagaccta caagatagtc ataaggttgc tgaccatgtg tttggtgatc
     7261 atagcatcgt ggctgatatt gatggctggc aaggtaacaa agaagccctc aaggtggacc
     7321 atgtctttac cagtaaggac ttcatcatcc gatcttctaa gactaccttt gaaggcggag
     7381 atgcgccagt cgtcagtgac cactatggtc tagaagtgac attaggctgg cgttagagca
     7441 tgtgctaaca ggcacaccac ataagagaag ccaagacaca taagaaactg cgatcatcta
     7501 gggggattag gagaacacaa agaggtctaa cgagctcaag gtagagctgg ttagacctct
     7561 ttagtcatgt cagtaaccct aaaaaaccag ggctgttttg tcaccaacca tctgagcttc
     7621 acagaaagta ccaccaagcg ttcagttgcc ttgctaaagt ctgcataggg gtatttctag
     7681 gagtgcttgg tgtgatccca agcaccaaga agcactgtga tcgctctttt caaaggctga
     7741 gaaatcacaa ggcgtagggt agggccctct gtagttattg tcctaaaagc gctctttttt
     7801 aaaacagcta tgatcatcta tagactgtct agctgttagg caatgtctgt gtgtcgttag
     7861 acgagtgtct ggagctggcc tccatgatga gctgggctaa ccgcgaaatg tcatcaggag
     7921 tccctcgcag ctcaaaatca cctagcagtg gaaagccaaa gcgtttggca tactgtttgg
     7981 ctgtcaggca atactgatgg ttaaagtttt tgttgcctga gccaataatc ccaagacaac
     8041 gctgggcgtt gccatgggca gcaataaact ctcccaaagg agtggtgagg atctccacct
     8101 caccagagtc aacgccattt ccgccttcta gataagtggg tagaatcgcc acaaactctt
     8161 ccttgacggg aaaagtctcg tgcttcaaat ctttaatgtt aatctgtttg acatggtaat
     8221 cgtaattgtc tgctagataa agggatagcc gcttgacaaa gctaagggtg ttgccactga
     8281 ggctaataaa aacaagggta atctgaggca taagtgtctc ctttttttat cctacaaggt
     8341 ttcttcataa gcttaccaca atcaagacca acaaacaagt aaagaagaaa cctagcggta
     8401 tccaaccaga caagaaggta caggcagtca aaaaaagcaa catttcaaaa aagagtgacc
     8461 ttcttaaaga aaggatgcgc ttgccctcga cttaaaaacg aggcaggcaa gtgccaaagt
     8521 ggccctctga tctccacaaa agagcgatca gtcaaaatct aaaagatgaa caacaaaaga
     8581 gaactttaca attgttttca cactctatta tagataatca ggtctagcta ccatgttatt
     8641 tttatctaaa acacaccatc tagagaaaga gagaacaaca tatgttgaca tcaaaacacc
     8701 ataatcttaa caaactagtc tggcgctacg ggctaacctc agcggcagcc gtccttctag
     8761 cctttggagg cgtggcaagc agcgttaagg ctgaagaagc ttctatgacg cagaatcaga
     8821 gacaagaaga aattaaaaaa attaaagagg gtctgaacaa atatccgcga atgtatgatg
     8881 aacaattttg ggggggcgta tctaataacc agtttctaga cgaactttat caggacaaac
     8941 tagaggaata tactaaagga gcacttacta agattttaga tttgattgaa aaaggtgcaa
     9001 caaaaggtga aaaaggggat cctggtgccc aaggacctaa aggcgaaaag ggtgaaaaag
     9061 gtgaccgcgg tgacaccgga gcacaaggtc cagtaggccc acaaggcgaa gcaggccaac
     9121 caggtgaaaa agctccagaa aagagcccag aagtgacacc aacaccagaa atgccagagc
     9181 aaccaggtga aaaagctcca gaaaagagca aagaggtaac tccagctcca gaaaaacctg
     9241 ctgacaaaga agctaaccaa acgccagaac gccgcaatgg caatatggct aagacacctg
     9301 tagccaacaa ccacagacgt ctaccagcaa ctggtgagca agccaaccca ttctttacag
     9361 cagcagcagt agcagtgatg acaacagctg gtgtcctagc cgttacaaaa cgcaaagaaa
     9421 acaactaatc ctctaaattg agaggcctta ctgataagca aacataatag agagagcccc
     9481 ttggttctct ctatttttgg tcgggagcag gcctttggta tcatgctcac gcctgagaga
     9541 tcccaaaaga tatcacaagc agctcactaa ccgttttcta agaaaaggtc acactaagcg
     9601 ctttcttagc agattctgcc ttttgctttt gtgtgtaaag tgttaaaata gggaaaagaa
     9661 atgctagatg aggaacgaaa tggcaaaaat aatgaacgta acaggagaag aagtcattgc
     9721 cttagcggcc acctatatga ccaagactga tgtggctttt gtggcaaagg ctttagcata
     9781 tgcaacagcg gcccatttct accaagtgag aaagtcaggc gaaccctata tcgtccatcc
     9841 gattcaggtg gcggggattc tggctgattt gcatctggat gctgtgacag ttgcttgtgg
     9901 ctttttacat gatgtcgtag aagatacgga cattacctta gatgagatcg aagcagactt
     9961 tggccatgat gctcgtgata tcgttgatgg tgtcaccaag ttaggtaaag ttgagtacaa
    10021 atctcatgag gagcaactcg ccgaaaacca tcgcaaaatg ctgatggcta tgtccaaaga
    10081 tattcgcgtg attttggtga aattagctga ccgcctgcat aatatgcgca ccctcaaaca
    10141 tttgcgcaag gacaaacaag agcgcatttc gcgcgaaacc atggaaatct atgccccctt
    10201 ggcgcatcgt ttggggatta gtcgcatcaa atgggaacta gaagatttgg cttttcgtta
    10261 cctcaatgaa accgaatttt acaaaatttc ccatatgatg aaagaaaaac gtcgcgagcg
    10321 tgaagcctta gtagaggcta ttgtcagtaa ggtcaaaacc tatacgacac aacaaggctt
    10381 gtttggagat gtgtatggcc gaccaaaaca catttattcg atttatcgga aaatgcggga
    10441 caaaaagaaa cgtttcgatc agatttttga tctgattgcc attcgttgtg tcatggaaac
    10501 gcaaagcgat gtctatgcta tggttggcta tattcacgag ctttggcgtc ccatgccagg
    10561 ccgcttcaag gattatattg cagctcctaa agctaatggc taccagtcga ttcataccac
    10621 tgtgtatggg ccaaaaggac ctattgagat tcaaatcaga actaaggaca tgcatcaagt
    10681 ggctgagtac ggggttgctg ctcactgggc ttataaaaaa ggcgtgcgtg gtaagatcaa
    10741 tcaagctgag caagccgttg gcatgaactg gatcaaagag ttggtagaat tgcaagatgc
    10801 ctcaaatggc gatgcagtgg actttgtgga ttcggtcaaa gaagacattt tttctgaacg
    10861 gatttatgtc tttacaccga caggggccgt tcaggagttg ccaaaagaat caggtcctat
    10921 tgattttgct tatgcgatcc atacgcagat cggtgaaaaa gcaacaggtg ccaaagtcaa
    10981 tggacgtatg gttcctctca ctgccaagtt aaaaacagga gatgtggttg aaatcatcac
    11041 caatgccaat tcatttggcc ctagtcgaga ctgggtaaaa ctggtcaaaa ccaataaggc
    11101 tcgcaacaaa attcgtcagt tctttaaaaa tcaagacaag gaattgtcag tgaataaagg
    11161 ccgtgatttg ttggtatctt attttcaaga gcagggctac gttgccaata aataccttga
    11221 caaaaaacgc attgaagcaa tccttccaaa agtcagtgtg aaaagcgaag aatcactcta
    11281 tgcagccgtt gggtttggtg acattagtcc tatcagtgtt tttaacaagt taaccgaaaa
    11341 agaacgccgt gaagaagaaa gggccaaggc taaagcagaa gcagaagaat tggttaaggg
    11401 cggtgaggtc aaacacgaaa acaaagatgt gctcaaagtt cgcagtgaaa atggagtcat
    11461 tatccaagga gcatcaggcc tcttgatgcg gattgccaag tgttgtaatc ctgtacctgg
    11521 tgatcctatt gacggctaca ttaccaaagg gcgtggcatt gcgattcaca gatcggactg
    11581 tcataacatt aagagtcaag atggctacca agaacgcttg attgaggttg agtgggattt
    11641 ggacaattcg agtaaagatt atcaggctga aattgatatc tatgggctca atcgtagtgg
    11701 cctgcttaat gatgtgctcc aaattttatc aaactcaacc aagagcatat cgacagtcaa
    11761 tgctcagccg accaaggaca tgaagtttgc taatattcac gtgagctttg gcattccaaa
    11821 tctgacgcat ctgaccactg ttgtcgaaaa aatcaaggca gttccagatg tttatagcgt
    11881 gaagcggacc aatggctaag aaaggataaa accatgaaac ttgtcttgca acgggtcaaa
    11941 gaggcctctg tttctattga tgggaaaatt gctggcgcta ttaaccaagg gttgttgttg
    12001 ttagtaggtg tgggaccaga tgataatgca gaagatttgg cttacgctgt gcgaaaaata
    12061 gtcaacatgc gcattttttc agatgctgat ggcaagatga atcagtctat ccaagacatc
    12121 aagggcagta tcttatctgt gtcgcaattt accctttatg ctgacaccaa aaagggaaac
    12181 cgtcctgcct ttactggtgc tgctaagcca gatttggcta ggcagttgta tgatagcttt
    12241 aatgaacaat tggcagagtt tgtgccagtt gagcgtggcg tttttggggc agatatgcag
    12301 gttagtctca tcaatgatgg accagttacg attattttag acacgaaatg tcattagtct
    12361 ctacaactaa gagattagaa aaaagcaagc aactgttgat agcgtgttgc ttgctttttt
    12421 tgtcagttaa tctcatcgtt ttagaagatc gtggttattt gtctttaggg ttatcaggta
    12481 taggtgtccc tgtataacgc aggtagctgt aaacttctcg ttcttcttcg gtataacgat
    12541 ctttatcata agctaaatga tagctagcat tctctccttc gggtcgcttg cccatataaa
    12601 ctgtgacgac acgattattc ttatcgtgat tatcctctac ttttccagtt aaggtatagt
    12661 ccataatacc aaaagcatcg agattgttgt agagtagttt agccttatca cgaggatcgt
    12721 ataaatctct gaagtctaag ttacgttcgc tagctgttaa gagctgctcg ctttttagca
    12781 atttgttggt gttgacatca acgtaattga tggtgaacag tttcaagtga ctgcgatcaa
    12841 agggatcata cggcttttcc ccttttttaa ggacgtaata tttctcagag ataaggtcgg
    12901 tgttgttcgt tttttcttcc tgaccagatt ttttattgat cccataagct tgttcccggt
    12961 ctttgatatg gtaagtaaac tcttgatcca ttggtaaaat cgtacggaaa atgtcattgt
    13021 catgagtgac gattgaggag tcacgttcat aaatcgtata gtctggatgg ctttcgttta
    13081 aaatgctttg tgcttgagct agtaattctt gagatgtgac ggtgccaccg atagctagtg
    13141 ttttcaatag tttagtattt ttgagaacgg gtctgaaatc atcatcaggg tttaaggggg
    13201 taaactgtac agtatatctc acatcgacag attttgctgg agtttgtatt ggtttttctt
    13261 tatatggtct aactcgcaca tgtcccctta acaaaaattc ttggacaggt tgggtgggca
    13321 aggttaccga atcatctttg tcagcaaagt agaccttgcc gtttcgatca gtaatggttg
    13381 catcgcttgc aaaatcaatg acctcaaagt agccgtcatt actgtggacg ttagcgatca
    13441 gccgttcttg aatagccttt aataagtcag ctttttcaag tttatgtggc atcgcgctac
    13501 tatttgtagc aaatggtttt gattttggac ttaagccttg ctctgtcttt cctccgtgag
    13561 caggttgtga tgttagatcg atttcaaaaa aatttataaa aactttttta tcggtacctt
    13621 caacgatacc tgccatactc acaactaact ggctgttatt gacaggtgga cggtctagta
    13681 gccacccata tccagcaata gcttggacag gcttgactgt tccaaatgtt aatgcaaaca
    13741 gcagtgcaat cactccaata gataagtaat ttttcataga aacctcctaa aagttaagtt
    13801 tcaatcccca ttattagaat aacataataa ttttatagat acaaacaaaa acctaatgat
    13861 tgtttttaaa tgatatctta atgataatgt catgataatg aaaaaagaga aataatacct
    13921 attttagtat aaacataaat tatttccccg ctaaatagcc atttgattga atttttttgc
    13981 taaaaatgaa taacccttat tcagctttaa tgattaaaaa agtcagaaaa tgcaaaatcg
    14041 tgctgacaac aaaccgaact gtgtgataaa gagtcatgtg ttataatggt ttaaagaccg
    14101 tcatgaaagg aatggctatg gagctaaaag actattttcc agagatgcaa gtaggccctc
    14161 atccgttagg agataaagag tgggtgagtg tcaaagaagg ggaccaatat gtgcattttc
    14221 ccaaatcatg tttatccgaa aaagagcgct tattacttga ggtggggctg ggtcagtgtg
    14281 aggtcttgca gccgctaggg tcaccttggc agcggtattt gcttgatcat cagggcaatc
    14341 cccctcagct gtttgagact tctcagttta tttacctcaa tcatcagcag actttaccag
    14401 atgacttagt tgagttgctc caacagatga ttgcagggct tgaggtcatt ttgcctatca
    14461 gtgcaaccca aacggcattt ttatgccgac aagcaatctc aataaaggtc ttgcgctggc
    14521 ttgaagatct cctgccaacg ctagaaagtg attttggttt ggccttaacc atgtttgttg
    14581 gaaatgcctg gtatcaggta gctgcaggta cattgagaga gtgttttgag gaggaatgtc
    14641 agctgttaac ggcctattta aggcaacaat caggcagaaa attattaaca ttttcaggac
    14701 tgatgctgtg gtctttgctg tcgcaccaca cttttttggc attgacgcgt cagtttcacc
    14761 aattcctaag tcctcaaagt gatatggccg atgtggttca cgcgctatgg tcagaacacg
    14821 gcaatctggt gcagacagcg cagcgcttgt atattcaccg taactccttg caatacaaac
    14881 ttgataaatt tgctcagcaa tcaggactcc acttgaagca attggatgat ttagcctttg
    14941 ctcatctctt tttgttgaaa tattaggaaa gccacagggc tttctttttt gctgcctgga
    15001 ctgtagctga taaggagaat gatagatcgt tcagcttgtt ttggctcctg tgaccggcct
    15061 gtgtttacat ggttttcttg ttttatggtt ccttacgact tgactagcct tgctattgtg
    15121 caagttgctc aaagaagttt ggtcgctttg tctctgtttt gaaagcgcta tttttgttat
    15181 aataaaagca tcatataaaa gatatcagcg gtttctagct ttgcagtcag ctagaacgtt
    15241 tgctgttcaa ataggagtta cacatggttg aattaaatct aaatcacatc tataaaaaat
    15301 acccaaatac tactcattat gccgttgaag attttgactt agacatcaaa gataaagaat
    15361 ttatcgtctt tgttggacct tcaggatgtg gtaaatcgac tactcttcgt atgattgcag
    15421 gtcttgagga catttctgaa ggagagttaa aaatcggtgg cgaagtggtg aatgacaagt
    15481 ctcctaaaga ccgtgatatt gccatggtct ttcaaaacta cgccctttac ccacacatga
    15541 ccgtgtatga taacatggcc tttggtttga aattacgtaa gtacaaaaaa gatgatattg
    15601 accgtcgtgt caaggaagct gcgcagatcc ttggtttgac cgaatttcta gagcgtaaac
    15661 cggctgacct gtctggtgga caacgccaac gtgttgccat gggacgtgct attgtccgtg
    15721 atgctaaggt attcttgatg gatgagcctt tgtcaaactt ggatgcgaag cttcgtgtct
    15781 ccatgcgtgc tgaaatcgca aagattcatc gtaggattgg ctcaacaact atttacgtta
    15841 cccatgacca gacagaagcc atgaccttgg cagaccgtat cgttatcatg agtgccacta
    15901 aaaaccctca aagtaatgga acgattggta aaattgagca agtaggttca ccacaagaat
    15961 tgtacaacct tccagctaat aaattcgttg ctggctttat cggaagccct gccatgaact
    16021 tctttgaagt ggaagttaaa gatggccgca ttgtgagtga agatggtctt gctattgcga
    16081 ttcctgaagg tcaagcaaaa atgcttgaag ctgctggtta caaggggaaa aaagtcactt
    16141 ttggtattcg tccagaagac atttctagta gacaaatcgt gcatgatact tatccaagtg
    16201 caactgtcac agcagaagtt ttggtttctg agttactggg ctctgagacg atgctctatg
    16261 tcaagcttgg acaaactgag tttgcttctc gtgtagatgc gcgtgatttc catagtccag
    16321 gggagcaagt tagcttgacc tttaatgtgg ctaaaggaca tttctttgac agagataccg
    16381 aacaagctat tcgttaaggt ataagcgata ttgataaaaa ggttgggttc cagccttttt
    16441 atcatgtcat ttgcgcaaac gattgcacaa aaagagaaaa aacgttaaaa taaaagatga
    16501 atgaatgatt aataggagaa gaataatgaa gaaacactgg tggcataaag ctacgattta
    16561 tcagatttac ccaagatcct ttaaagacac caatggcaat ggtattggtg atttaaaagg
    16621 cattaccagt caactggact acttgcaaaa acttggcatt acagccattt ggttatctcc
    16681 tgtttaccaa agtccaatgg atgacaatgg ttatgacatc tctgactatg aagcgattgc
    16741 tgatgttttt ggagacatgg cagatatgga tgagctttta gcagcagcta atgagcgagg
    16801 cattaagatt atcatggact tggtggtcaa ccatacgtct gatgagcatg cttggtttgt
    16861 tgaagctaga gaaaatccca atagtcctga gcgtgatttt tatatttggc gagatgaacc
    16921 taacgatttg acttctattt ttagtggctc agcttgggaa tatgataatg catcaggtca
    16981 atattatttg caccttttta gcaaacgtca gccagatctc aactgggaga atgaagcttt
    17041 acgtcataaa atttacgata tgatgaattt ctggattgcc aaaggcatag gtggttttcg
    17101 gatggacgtg attgacctga ttgggaaggt tcctgacttg gaaatcacag gtaacgggcc
    17161 gcggttacac gattacctca aagaaatgaa tcaagcaacc tttggcaatc atgacgtgat
    17221 gactgtcggt gagacttggg gagcaacgcc tgaaattgct cgccagtatt ctcgccctga
    17281 aaataaagag ttatccatgg tcttccaatt tgagcatgtg ggtcttcaac ataaacctga
    17341 cgctcccaag tgggattatg cggaagaact ggatgttcct gctctgaaag ctatttttag
    17401 caagtggcag acagaattaa agttgggaga aggctggaat tcgctttttt ggaataacca
    17461 tgacttgcca cgggtcttat ccatttgggg caatgacagc acttaccgag aaaaatcagc
    17521 caaggcttta gctattttac tgcatttgat gcgaggaacc ccttacattt accaaggaga
    17581 agagattggc atgaccaatt atccttttaa agacttaacc gaggttaatg atattgagtc
    17641 ccttaactat gctaaggaag ctatgggaaa tggagtgtca gctgcgcgtg tgatggatag
    17701 catccgtaag gtaggacgag acaatgctag aacgccaatg cagtggtcta aggacacaca
    17761 tgctggcttt tctaaagccc aagagacttg gttgccggtc aaccccaact accaagacat
    17821 caatgtggcc gatgcccttg ctgatccaga ttctattttt tacacttacc aaaaattgat
    17881 tgccttgcgt aaggagcaag actggctagt tgaagcggat tatcacctct tgccaacagc
    17941 tgataaagta tttgcttatc agcgtcaact tggagaagag acgtatgtga ttgttgtcaa
    18001 tgtgtctgat gaggagcaag tctttgccaa agatttagca ggtgcacaag tgatcatcgc
    18061 caatacagat gtggacacgg tattagagac caagcactta caaccttggg atgccttttg
    18121 tctcaaactg aaggcctagc agttgtatgt gatttgagtt tacccaacag ccaagcgagc
    18181 ggaaactcgt tttggctgtt tgatttttga gatcctatta aggggtgata gtcattgttt
    18241 gagctgtgtt ctaagttgaa gtgcggcatg tcttgcaagc gattgcgcaa tgtgataaga
    18301 tagtcttgtt tgaatgttat actaaatgga ggtcttatga aaaagaaagt caaccaagga
    18361 tcaaagcgct atcagtatct gttaaaaaag tgggggatag gttttgtaat cgctgcaact
    18421 gggactgtca tgttagggtg cacccctagt atcttaacac atcaagttgc tgctaaaacc
    18481 attgttggac tagcccgcga tgaagctcaa caaggagatg gcaatgctaa atctggtgat
    18541 ggttttcaat cgtctagtaa ggaggctaaa ccagttttag acagctcgtc agctaatcct
    18601 gctagtattg ctgagcatca tttgcgtatg cattttaaaa cattgccagc tggtgagtcg
    18661 ctaggaagct tgggactttg ggtgtgggga gatgtggatc aaccttcaaa ggattggcca
    18721 aatggtgcta tcaccatgac aaaggcgaaa aaagatgact atggctatta tctagatgtg
    18781 ccactagcag ctaaacaccg ccagcaagtg tcttatctca ttaataataa agctggagag
    18841 aatctttcaa aggaccagca catctcgctt ctcacgccaa gaatgaatga agtttggata
    18901 gacgagaatt accatgcgca cgcttatcga cctttgaaaa aaggttacct tcgaatcaac
    18961 taccacaatc aatcgggaca ctacgataac ttagctgtct ggacctttaa agatgtcaaa
    19021 accccaacga ccgactggcc aaatggactt gacttgtcac ataaagggcc ttatggagct
    19081 tatgttgatg tccccttcaa agaaggagct aacgaaatcg gatttttaat ccttgataaa
    19141 agtaagacag gagatgctat taaagtgcaa ccaaaagatt atctgtttaa agagttagac
    19201 aatcatactc aggtttttgt caaagacact gacccaaaag tctacaacaa tccttattat
    19261 attgatcagg ttagtctcaa aggtgctgaa caaaccacgc caaatgagat taaagccatt
    19321 tttacgacct tagatgggct tgatgaagat gcggtgaaac aaaacatcaa gatcactgac
    19381 aaagcaggga aaactgttgc aattgatgag ttgacacttg acaaggataa gtctgtaatg
    19441 acattaaagg gtgattttaa ggcgcaaggt gcagtctaca cggttacatt tggagaagtt
    19501 agccaagtcg ctcgccaatc ctggcaatta aaagataaac tctatgctta cgatggtgaa
    19561 cttggagcta ccctagctaa ggatggttcc gttgatttag cgctatggtc tccaagtgct
    19621 gatactgtta aggttgtcgt ttatgataaa caagatcaga caaaggttct tggtcaagct
    19681 aatttgacca agtcggacaa gggtgtttgg agagctcatc tgacttctga tagtatcaag
    19741 ggcattagtg attacacagg ctactattac ctttatgaaa tcacgcgcgg tcaggaaaaa
    19801 gtcatggttt tggatcctta cgccaaatct ctcgctgcct ggaatgatgc gactgctact
    19861 gatgacatca aaacagcaaa agctgccttt attgatccaa gcaaactagg accaacaggc
    19921 cttgattttg ccaaaattaa caactttaaa aagcgtgaag acgctattat ctatgaagca
    19981 catgtgcgag attttacgtc agataaggct ctagaaggta agttaacata cccttttggg
    20041 actttttcag ctttcgttga acagctagac tatctcaaag acttgggggt tacccacgtt
    20101 caattgctac cggttttgag ttatttttat gccaatgagc tggacaagag ccgctcaaca
    20161 gcctacacgt cttcagacaa taattacaac tggggttatg acccacaaca ctactttgcc
    20221 ctttctggca tgtattcggc aaatcctaat gaccctgctt tacgtatcgc agagcttaaa
    20281 aaccttgtca atgagattca caaacgtggt atgggtgtta tttttgatgt ggtttataac
    20341 cacacggcta gaacctatct ctttgaagat ttggaaccca actactatca ttttatgaat
    20401 gctgatggta cagctagaga gagttttggc ggaggtcgtc taggaacgac acatgccatg
    20461 agtcgtcgta tcttggtgga ttcgattact tatctgactc gtgaattcaa ggtagacggt
    20521 tttcgtttcg acatgatggg tgaccatgat gcggcagcta ttgagcaagc ctttaaggca
    20581 gccaaagcca ttaatccaaa taccattatg attggcgaag gctggcgtac ctaccaaggt
    20641 gatgagggga aaaaagaaat tgcggcagat caagattgga tgaaagcaac caatacggtc
    20701 ggtgttttct ctgatgatat cagaaatacc ctcaagtcag gttttccaaa tgaaggcaca
    20761 gcagccttta ttactggtgg cgcaaaaaat ctagaaggac tgttcaaaac gatcaaagca
    20821 cagcctagta actttgaagc agatgcccca ggagatgtag tgcagtatat tgcagcccat
    20881 gacaacctga ccttacatga tgtcattgcc aaatccatca ataaggatcc taaagtggct
    20941 gaagaagaga ttcacaagcg tattcgtcta ggaaatacca tgattttaac tgctcaaggg
    21001 actgccttta tccattctgg tcaggaatat ggacgaacca agcagcttct aaatcccgac
    21061 tacaagacaa aggtgtctga tgataaggtg ccaaataagg cgactctgat tgatgctgta
    21121 gcgaaatacc cttacttcat ccacgattct tatgattcgt ctgatgcggt caatcatttt
    21181 gactgggcaa aggcaacaga ttccatagct cacccgatta gcaaccaaac aaaagcctat
    21241 acacagggac taattgcgtt gcgtcgctca acagatgcct ttacaaaagc aaccaaagct
    21301 gaggtagatc gggatgtgac cttgatcacc caagcaggac aagatggtat tcaacaagag
    21361 gacctcatca tgggttacca aacggtggca tcaaatggag atcgctatgc tgtctttgtc
    21421 aatgcagaca acaagacccg caaggtagtt ttacctcaag cctaccgcta tttgccagga
    21481 gcccaagtgc ttgctgatgc tgagcaagct ggtgttactg ccattgctaa gcctaaggga
    21541 gtccagttta ccaaagaagg cttgactatt gatggcctaa ctgccctggt cctcaaagta
    21601 tcctcaaaaa cggctaatcc ctctcagcaa aagagtcaga caggcaatca tcaaaccaaa
    21661 acaccagatg gctcaaaaga cctagacaaa tcattaatga ctaggccaaa aagagctaaa
    21721 acaaaccaaa agctcccaaa aacgggtgaa gcctcctcaa aaggcttatt agcagctgga
    21781 gtagctctgc ttttattggc tattagcctg ttgatgaagc gccaaaaaga ttagggtggc
    21841 gttaatagag acaaaaagat tgctgtttgc ggattctttt tgacggctat aaaagctctg
    21901 agctgtgaaa agaccttgtg attgagaaaa ttgctacttt agtgtatcat gagaccaaaa
    21961 gagaaggaga catccatgac atttgaagaa atcgttgcga attttatacc gtcgagtgtt
    22021 gcagaagtca catcagctat tgctagtggc aaagacatga ttgtcttttt aggacgttcg
    22081 agctgtcctt attgtcgccg ctttgctcct aagttggcac aagtggcaac agataatcaa
    22141 aaagacgtct attttgtgga tagcgaaaac gctgctgatg ctgctgagct tgctgccttt
    22201 cgtgagaact accaattagt gacagttccg gctttgctgg ttagttacga tcagcaccaa
    22261 agggctgtat gtgattcaag tttgacacca gatgacatct tagctttttt gactcgtgag
    22321 taaagcactg cgcttagcgt ctcgtttaaa gaagaaatca ggtaacgtct agtcttgcta
    22381 taccgcttga tttttgatat agtaagacat gacttttata gaataaaaag gagacattat
    22441 gggatttcca acaattttaa tgtttgtagt gatgcttgga ttgatttggt ttatgcaacg
    22501 tcaacaaaaa aaacaagcgc aagaacgcca aaatcagtta aacgctattg aaaaaggaga
    22561 cgaagtcgta acgattggtg gcatgtttgc gattgttgac gaagtcgata caacagctaa
    22621 aaagattgtg ttagatgtgg atggcgtctt tttgacattt gagctatcag ctattaagcg
    22681 tattgtaaca aaagctacca cagaaacgac actggttgaa acaaaagaaa ccattgttgt
    22741 taatgagcct gctgttgaga cagtagatag cactgacact gacagtgcca ttgaaagcca
    22801 ttaaggcggg gaaagtttgg atgaaatatg ccaaactttt ttgttttgat ccctggactg
    22861 aaacagttat tctgatgcta acaggttcat gaaaagctga cacatctatc agaggatagg
    22921 tgaacatttt gtgaagataa gatctaattg ataaaaaaca agccaaaagg cgtgaaatat
    22981 gataaaatat gagataagta tgcttatcaa taaggaaaaa acatgtttgg attaaaagcg
    23041 aaatcaacaa aaaaagtttt ggggagtatc ccaaagcata ttggaattat catggatggt
    23101 aatggacgtt gggccaaaaa aagactaaaa cctagagtgt ttgggcataa agctgggatg
    23161 gatgctttac aagaagtaac gattactgca tctgagttgg gggttaaagt tctgacagtc
    23221 tatgcctttt cgacagaaaa ctggtccaga ccccaagatg aggtatcttt tatcatgaat
    23281 ttaccagtag ccttctttga caaatatgtg cctgtgcttc atgagaacaa tgtaaagatt
    23341 caaatgattg gagagactag tcgtttacct gaagatacct tggcagcgct aaatgcagcc
    23401 atcgacaaaa caaaacgtaa tacgggttta attttgaatt ttgctctcaa ttatggagga
    23461 cgtgctgaga ttaccagtgc tgttcgcttt attgctcaag atgtcttaga tgccaaatta
    23521 aatccaggag atattacgga ggatttgatt gctaattact tgatgacaga ccatctgcca
    23581 tatctctacc gagaccccga tttgattatt cgcaccagtg gtgagctgcg tttgagcaat
    23641 ttcttgcctt ggcaatcagc ttacagtgaa ttttatttca caccagtctt gtggcctgat
    23701 tttaaaaagg cagagctact aaaggccatt gcggattata accgccgcca acgtcgtttt
    23761 ggcaaggtct aaaaggagat agttatgaaa gaacgtgttg tttggggggg agtagcagta
    23821 gctattttcc taccttttct cataatagga aatctaccat tccaattatt tgtaggcgtt
    23881 ttggccatga ttggggtatc agaattactg aaaatgaaaa gattagaagt cttttctttt
    23941 gaaggtgttt ttgccatgtt agctgccttt gtattggcag ttccgatgga ccattacctt
    24001 acttttttac caattgatgc gaatgttgct ttttacagct taatggtttt tttcattttg
    24061 gcaggtactg ttttaaatag cagagcttat tcatttgatg atgcggcctt tccgattgca
    24121 actagttttt atgttgggat tggttttcaa catttgatca atgctcgcct gtcaggaatt
    24181 gacaaggtct ttttggcctt atttatcgtt tgggccactg atattggagc atatctgatt
    24241 gggcgtcagt ttggcagacg caaactattg cctacagttt ctccaaacaa aaccattgaa
    24301 ggtagtttag gagggatcgc ttgtgcagtc cttgtgtctt ttatctttat ggtgattgat
    24361 aggtctgttt atgcaccaca tcactttttg accatgttgg ttttggtcgc tcttttttcc
    24421 atttttgccc aatttggtga tttggttgaa agtgctctca aacgtcactt tggtgtcaaa
    24481 gattcaggta agcttatccc gggacatggt ggtattttag accgctttga ttccatgatt
    24541 tttgtttttc ccatcatgca tctttttggt ttattttaat cttaagaggt aatgtttgga
    24601 gtcgcaacaa cgcgacagaa ctcaaaaaag caatagactg aaaggaaatc tatgttagga
    24661 ataataacct ttattattat ttttggtatt ttagtgattg tccatgaatt tggacatttc
    24721 tattttgcta aaaaatcagg cattctagta agagaatttg ccattggaat gggccctaaa
    24781 attttttctc atgttgacca aggaggaact ctttatacct tgaggatgtt acccttgggc
    24841 ggttatgtgc gaatggctgg ttggggtgat gacaaaactg agatcaaaac aggtac
//
LOCUS       DAXMQE010000025        24798 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.025, whole genome shotgun sequence.
ACCESSION   DAXMQE010000025 DAXMQE010000000
VERSION     DAXMQE010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24798)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24798)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24798
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.025"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            <1..697
                     /locus_tag="ACF4ZO_001237"
     CDS             <1..697
                     /locus_tag="ACF4ZO_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HFD5486774.1"
                     /translation="ALEGAKKAGSDYVELDLILTKDNHFVVSHDNRLKRLAGVNKTIR
                     NLTLKEVEHLTSHQGHFSGRFVSFDTFYQKAKKLNMPLLIELKPIGTEPGNYVDLFLE
                     TYHRLGISKDNKVMSLDLEVIEAIKKKNPSITTGYIIPIQFGFFGDEFVDFYVIEDFS
                     YRSYLSSQAFWNNKEIYVWTINDPKRIEHYLLKPIQGIITDQPALTNQLIKDLKQDNS
                     YFSRLVRIISSLY"
     gene            824..1096
                     /gene="rpsP"
                     /locus_tag="ACF4ZO_001238"
     CDS             824..1096
                     /gene="rpsP"
                     /locus_tag="ACF4ZO_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HFD5486775.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRAPRDGRFIETVGTYNPLV
                     AENQITIKEDRVLEWLSKGAQPSDTVRNILSKAGVMAKFHDQKFSK"
     gene            1106..1345
                     /locus_tag="ACF4ZO_001239"
     CDS             1106..1345
                     /locus_tag="ACF4ZO_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HFD5486776.1"
                     /translation="MDTIENLIIAIVKPLISQPDNLTIKIEDTPDFLEYHLDLDAQDI
                     GRVIGKKGRTITAIRSIVYSVPTLGKKVRLVIDEK"
     gene            2277..5303
                     /locus_tag="ACF4ZO_001240"
     CDS             2277..5303
                     /locus_tag="ACF4ZO_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="leucine-rich repeat domain-containing protein"
                     /protein_id="HFD5486777.1"
                     /translation="MKKHLKTVALTLTTVSVVTHNQEVFSLVKEPILKQTQASSSISG
                     ADYAESSGKSKLKINETSGPVDDTVTDLFSDKRTTPEKIKDNLAKGPREQELKAVTEN
                     TESEKQINSGSQLEQSKESLSLNKRVPSTSNWEICDFITKGNTLVGLSKSGVEKLSQT
                     DHLVLPSQAADGTQLIQVASFAFTPDKKTAIAEYTSRAGENGEISQLDVDGKEIINEG
                     EVFNSYLLKKVTIPTGYKHIGQDAFVDNKNIAEVNLPESLETISDYAFAHLALKQIDL
                     PDNLKAIGELAFFDNQITGKLSLPRQLMRLAERAFKSNHIKTIEFRGNSLKVIGEASF
                     QDNDLSQLMLPDGLEKIESEAFTGNPGDDHYNNRVVLWTKSGKNPYGLATENTYVNPD
                     KSLWQESPEIDYTKWLEEDFTYQKNSVTGFSSKGLQKVKRNKNLEIPKQHNGVTITEI
                     GDNAFRNVNFQNKTLRKYDLEEVKLPSTIRKIGAFAFQSNNLKSFEASDDLEEIKEGA
                     FMNNRIETLELKDKLVTIGDAAFHINHIYAIVLPESVQEIGRSAFRQNGANNLIFMGS
                     KVKTLGEMAFLSNRLEHLDLSEQKQLTEIPVQAFSDNALKEVLLPASLKTIREEAFKK
                     NHLKQLEVASALSHIAFNALDDNDGDEQFDNKVVVKTHHNSYALADGEHFIVDPDKLS
                     STIVDLEKILKLIEGLDYSTLRQTTQTQFRDMTTAGKALLSKSNLRQGEKQKFLQEAQ
                     FFLGRVDLDKAIAKAEKALVTKKATKNGQLLERSINKAVSAYNNSAIKKANVKRLEKE
                     LDLLTGLVEGKGPLAQATMVQGVYLLKTPLPLPEYYIGLNVYFDKSGKLIYALDMSDT
                     IGEGQKDAYGNPILNVDEDNEGYHALAVATLADYEGLDIKTILNSKLSQLTSIRQVPT
                     AAYHRAGIFQAIQNAAAEAEQLLPKPGTHSEKSSSSESANSKDRGLQSNPKTNRGRHS
                     AILPRTGSKGSFVYGILGYTSVALLSLITAIKKKKY"
     gene            5323..5724
                     /locus_tag="ACF4ZO_001241"
     CDS             5323..5724
                     /locus_tag="ACF4ZO_001241"
                     /EC_number="1.-.-.-"
                     /EC_number="1.4.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004733 - pyridoxamine phosphate oxidase
                     activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_process: GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HFD5486778.1"
                     /translation="MITQEMKDLINNQLAMVATVDAKGQPNIGPKRSMRLWDDKTFIY
                     NENTDGQTRINIEDNGKIEIAFVDRERLLGYRFVGTAEIQTEGAYYEAAKKWAQGRMG
                     VPKAVGIIHVERIFNLQSGANAGKEINSESN"
     gene            complement(5904..6779)
                     /locus_tag="ACF4ZO_001242"
     CDS             complement(5904..6779)
                     /locus_tag="ACF4ZO_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HFD5486779.1"
                     /translation="MPASKKVIIIFILNLSFSLIEFIFGTLFFSGAILADAVHDFGDA
                     IAIGISAILERKAVKKESSNFSLGYKRFSLLGALTTNLILISGSLLVMIETIPKLWHP
                     TIVNYDGMFVLAIFAIIINGFASFIIHSNQTKNEEILSLHFLEDILGWLAIIILSLIL
                     KWKPWYILDPLLSIAIASFILSKALPKLVATANIFLDGVPDSIDYCALHHELSQLPHI
                     VSVNQLNVWSMDGIDHRATIHCCLRESTTEKHCKKSIRLICQRYNINSVTVEIDTSLN
                     EHQHHCSSLSSIEVN"
     gene            6915..7436
                     /locus_tag="ACF4ZO_001243"
     CDS             6915..7436
                     /locus_tag="ACF4ZO_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFD5486780.1"
                     /translation="MTKDRQIKKTKTAIYSAFLALLQKKEYSKITVRDMIALANVGRS
                     TFYAHYESKEMLLKELCEELFHHLFRQKRNVTFEDYLVHILKHFEQNKDSIATLLLSN
                     DPYFLLRFKNELEHDVYPNLRCKYIDKTTIPEVFLKQFVLSSFIETLKWWLHQRQRMS
                     ANELLKYYLELIK"
     gene            7651..8169
                     /gene="rimM"
                     /locus_tag="ACF4ZO_001244"
     CDS             7651..8169
                     /gene="rimM"
                     /locus_tag="ACF4ZO_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Essential for efficient processing of 16S rRNA;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HFD5486781.1"
                     /translation="MEYFNVGKIVNTQGLQGEMRVLSVSDFAEERFKKGSQLALFDDK
                     DQFVQEVTIVSHRKQKNFDIIKFKDMYHINAIEKYKGYTLKVSKANQGDLQEGEFYYH
                     QIIGMAVYEKDRLIGYVKEILQPGANDVWVVKRQGKRDLLLPYIPPVVLSVDVPNKRV
                     DVELMEGLDDED"
     gene            8159..8878
                     /gene="trmD"
                     /locus_tag="ACF4ZO_001245"
     CDS             8159..8878
                     /gene="trmD"
                     /locus_tag="ACF4ZO_001245"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052906 - tRNA
                     (guanine(37)-N1)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HFD5486782.1"
                     /translation="MKIDILTLFPEMFAPLEHSIVGKAKEKGLLDIHYHNFRDYAEKA
                     RHVDDEPYGGGQGMLLRAQPIFDTIEQIEAKKPRIILLDPAGKPFTQAYAEELALEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDFVLTGGELAAMTIVDATVRLIPQVLGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMTVPDVLMSGHHERIRLWRLEESLRKTYLRRPDLL
                     ERYDFSEEERKLLDKIKEALG"
     gene            8890..9882
                     /locus_tag="ACF4ZO_001246"
     CDS             8890..9882
                     /locus_tag="ACF4ZO_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HFD5486783.1"
                     /translation="MKDKAYDITIIGGGPIGLFAAFYAGLRGVTVKIIESLSELGGQP
                     AILYPEKMIYDIPAYPSLTGVELTENLIKQLSRFEDRTTICLKEEVLTFDKVKGGFSI
                     RTNKAEHFSKAIIIACGNGAFAPRTLGLESEENFADHNLFYNVHQLDQFAGQKVVICG
                     GGDSAVDWALALEDIAESVTVVHRRDAFRAHEHSVELLKTSTVNLLTPYVPKALKGIG
                     NLAEKLVIQKVKEDEVLELELDSLIVSFGFSTSNKNLKNWNLDYKRSSITVSPLFQTS
                     QEGIFAIGDAAAYNGKVDLIATGFGEAPTAVNQAINYIYPDRDNRVVHSTSLID"
     gene            10060..11118
                     /locus_tag="ACF4ZO_001247"
     CDS             10060..11118
                     /locus_tag="ACF4ZO_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HFD5486784.1"
                     /translation="MTTTDKETFSSFMNKILAGTAIAIVVALIPNAILATFLKPLLPN
                     MAATEFLHIVQVFQFFTPIMAGFLIGQQFKFNPMQQLAVGGAAYIGSGAWAYTEVIQK
                     GVATGTFQLRGIGDLINMMITASLAVLAVKYFGNRFGSLTIILLPITIGTGVGYIGWK
                     FLPYVSYVTTLIGQGINSFTTLQPILMSILIAVAFSLIIVSPISTVAIGLAIGLNGMA
                     AGAASMGIASTAAVLVWATLKVNKSGVPIAIALGAMKMMMPNFLKHPIMAIPMVFTAA
                     ISSLTVPLFNLVGTPASSGFGLVGAVGPIASLAGGSSILIIILAWIIVPFAVAFAAHK
                     VSKDILKLYKEDIFVFEG"
     gene            11131..12054
                     /locus_tag="ACF4ZO_001248"
     CDS             11131..12054
                     /locus_tag="ACF4ZO_001248"
                     /EC_number="1.1.1.169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000964166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008677 - 2-dehydropantoate 2-reductase
                     activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HFD5486785.1"
                     /translation="MLVYIAGSGAMGCRFGYQISKTNNDVILLDNWEDHINAIKENGL
                     VVTGDVEETVKLPIMKPTEATQEADLIILFTKAMQLPQMLQDIKGIIGKETKVLCLLN
                     GLGHEDVIRQYIPEHNILMGVTVWTAGLEGPGRAHLQGVGALNLQSMDPNNQDAGHQV
                     ADLLNKANLNATYDENVVPNIWRKACVNGTMNSTCALLDCTIGELFASEDGLKMVKEI
                     IHEFVIVGQAEGVELNEEEITQYVMDTSVRAAHHYPSMHQDLVQNHRLTEIDFINGAV
                     NTKGEKLGINTPYCRMITELVHAKEAVLNIQ"
     gene            12310..13023
                     /locus_tag="ACF4ZO_001249"
     CDS             12310..13023
                     /locus_tag="ACF4ZO_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFD5486786.1"
                     /translation="MAKITEENYVSLEDLMQLLNSSESTIRRDLGELEQEGRLHRVHG
                     GAELFHSLQEELSNQEKSVKNSHIKKTIAQRASQFIYDNDVIFIDAGTTTEFLLPFLQ
                     AKNLTVVTNSIHHAARLVELSIETIIVGGYVKQTTDASIGNVALEQIRQMNFDKAFLG
                     MNGIDDSYLTTPDMEEAVIKKAVLSNAKLAYILVDGTKIGQVSFVKVAPINDVTIITL
                     GGSASILKQIKEKAKVIEL"
     gene            13020..13931
                     /gene="pfkB"
                     /locus_tag="ACF4ZO_001250"
     CDS             13020..13931
                     /gene="pfkB"
                     /locus_tag="ACF4ZO_001250"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008662 - 1-phosphofructokinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HFD5486787.1"
                     /translation="MIYTVTLNPSIDFIVRIDQINLGSVNRMASDDKFAGGKGINVSR
                     ILQRLDIASTATGFLGGFTGRFIEESLSAEGVKTDFVKGDQDTRINVKIKSQEETEIN
                     GQGPVISREQLEDLKTKLSQLTAEDTVVFAGSAPANLGNAVYKELLPLVRQSGAQVVC
                     DFEGQTLIDALTYNPLLVKPNNHELEAIFGTILTSLDDVETYARRLLEMGAQNVIISM
                     AGDGALLVTKEATYFAKPIKGEVKNSVGAGDSMVAGFTGEFMKSQNPIEALKWGVACG
                     TATAFSDDLATIAFIKETYHKVEVEKR"
     gene            13928..15874
                     /locus_tag="ACF4ZO_001251"
     CDS             13928..15874
                     /locus_tag="ACF4ZO_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-specific PTS transporter subunit EIIC"
                     /protein_id="HFD5486788.1"
                     /translation="MKIQDLLRKDIMILDLQAISKEVAIDEMITKLVEKDIVHDFDVF
                     KKSIMTREEQTSTGLGDGIAMPHSKNIVVDKPAVLFAKSNKGVDYKALDGQPTDLFFM
                     IAAPQGANDTHLAALAELSQYLLKDGFADKLRAAATPEAVIAVFDEASTAKEEVVAPT
                     SGQDFIVAVTACPTGIAHTYMAEEALKKQAAEMGVAIKVETNGASGVANRLTAEDIQR
                     AKGVIVAADKAVEMDRFDGKQFIARPVADGIKKSQELISLILNNEGHTYHAKNRKSET
                     AVSSEKTSLGGAFYKHLMGGVSQMLPFVIGGGIMIALAFLLDNMLGVPNDQLGSLGSY
                     HEIAAIFMNIGGAAFSFMLPVLAGYIAYSIAEKPGLVAGFVAGAIASSGLAFGKVPFA
                     AGGEVSLGLTGVPSGFLGTLVGGFLAGGVILALRKLLAGLPRSLEGVKSILLYPLLGV
                     LVTGFLMLFVNIPMAAINTALNDFLQGLSGSSAVLMGLLVGGMMAVDMGGPVNKAAYV
                     FGTGTLAATVANGGSVVMAAVMAGGMVPPLAVFVATLLFKDKFTKEERESGLTNIVMG
                     LSFITEGAIPFGAADPARAIPSFIAGSALTGALVGLAGIKLMAPHGGIFVIALTSNPI
                     LYLVFVVIGALVSGILFGALRKKA"
     gene            15967..16566
                     /locus_tag="ACF4ZO_001252"
     CDS             15967..16566
                     /locus_tag="ACF4ZO_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HFD5486789.1"
                     /translation="MKVKKRRRRAKSSVNRLVLGLVLLNLIVSMWTLKLGNQRLAPYA
                     DHETLTFVRKISHAAQSVAQKKQLYSSVMMAQAILESNNGKSQLSQKPYYNFFGIKGS
                     YKERSVIFPTLEDDGQGNLYQIDAAFRSYGSLTACFLDYARVLNDPLYDKTHKKFWSH
                     YQDATATLTGTYATDTTYHTKLNELIEWYQLTNFDGLMK"
     gene            16719..17426
                     /locus_tag="ACF4ZO_001253"
     CDS             16719..17426
                     /locus_tag="ACF4ZO_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HFD5486790.1"
                     /translation="MTKKKGKLVLISLFVLAACLGAYSAMRQSHKTSNVSAETIASSS
                     TRHFIDEIGPTASTIGQERDLYASVMIAQAILESSNGKSSLSQAPYYNFFGIKGAYNG
                     SSVTMSTWEDDGNGNTYTIDQAFRAYPSIADSLNDYADLLSSSTYIGARKSNTLSYQD
                     ATAALTGLYATDTSYNLKLNNIIATYGLTAYDVANSSAQETGLATSGYVWNEYRRNYT
                     DAETLAVDEAWAKRMTY"
     gene            complement(17483..17800)
                     /locus_tag="ACF4ZO_001254"
                     /pseudo
     CDS             complement(17483..17800)
                     /locus_tag="ACF4ZO_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(17998..18342)
                     /locus_tag="ACF4ZO_001255"
     CDS             complement(17998..18342)
                     /locus_tag="ACF4ZO_001255"
                     /inference="COORDINATES: protein motif:HMM:NF014875.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exotoxin beta-grasp domain-containing protein"
                     /protein_id="HFD5486791.1"
                     /translation="MLRTNTIAGNFFIDGQQQKTLINPIKIDKDIVTIQEFDFKIRKF
                     LMESKEIYLTKSPYIRGSLEIHSKNRKHEKINLYDAKPNSTRSDVFKKYKDNKTINMK
                     DFSHFDIYLWTK"
     gene            complement(18383..19396)
                     /locus_tag="ACF4ZO_001256"
     CDS             complement(18383..19396)
                     /locus_tag="ACF4ZO_001256"
                     /EC_number="3.4.22.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635407.1"
                     /note="This family includes IgM or IgG-cleaving cysteine
                     proteases; Derived by automated computational analysis
                     using gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IdeS/Mac family cysteine endopeptidase"
                     /protein_id="HFD5486792.1"
                     /translation="MRKRCYSTSAVVLAAVTLFALSVDRGVIADSFSANQEIRYSEVT
                     PYHVTSVWTKGVTPPAKFTQGEDVFHAPYVAKQGWYDITKTFNGKDDLLCGAATAGNM
                     LHWWFDQNNEKIEAYLKKHPDKQKIMFGDQELLDVRKVINTKGDQTNSELFNYFRDKA
                     FPGLSARRIGVMPDLVLDMFINGYYLNVYKTQTTDVNRTYQEKDRRGGIFDAVFTRGD
                     QSKLLTSRHDFKEKTLKEISDLIKKDKALGLSHTYANVRINHVINLWGADFDSNGNLE
                     AIYVTDSDSNASIGMKKYFVGVNSAGKVAISAKEIKEDNIGAQVLGLFTLSTGQDSWN
                     QTN"
     gene            19900..20057
                     /locus_tag="ACF4ZO_001257"
                     /pseudo
     CDS             19900..20057
                     /locus_tag="ACF4ZO_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051153.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
     gene            20305..20685
                     /locus_tag="ACF4ZO_001258"
     CDS             20305..20685
                     /locus_tag="ACF4ZO_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HFD5486793.1"
                     /translation="MQLVREKEFVNQYHYDARNLEWEKENGTPETNFEVTFQLIDKDE
                     QQKETVIVSVLQFVIVKEEFVISGVISQMVRILDRLVDKPSEFTQEEVESLAAPLLDM
                     VKRLTYEVTEIALDRPGIHLEFKN"
     gene            20685..21533
                     /locus_tag="ACF4ZO_001259"
     CDS             20685..21533
                     /locus_tag="ACF4ZO_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HFD5486794.1"
                     /translation="MKLAVITDSTATLPIDLKQDKAIFSLDIPVIIDDETYFEGRNLS
                     IDDFYQKMADSQNLPKTSQPSLSELDNLLGLLSSKGYTHVIGLFLAGGISGFWQNIQF
                     LAEEHPEIEMAFPDSKITSAPLGSMVKNVLDWSRQGMTFQAILNKLQEQIDRTTAFIM
                     VDDLNHLVKGGRLSNGSALLGNLLSIKPILRFDEEGKIVVYEKVRTEKKAMKRLVEIL
                     NDLIADGQYNVSIIHSKAQDKADYLKRLLQDSGYQYDIEEVHFGAVIATHLGEGAIAF
                     GVTPRL"
     gene            21658..22866
                     /locus_tag="ACF4ZO_001260"
     CDS             21658..22866
                     /locus_tag="ACF4ZO_001260"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001680 - tRNA 3'-terminal CCA addition
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HFD5486795.1"
                     /translation="MKLMTMPSEFQKALPILTKIKEAGYEAYFVGGSVRDVLLERPIH
                     DVDIATSSYPEETKAIFNRTVDVGIEHGTVLVLENGGEYEITTFRTEDVYVDYRRPSQ
                     VSFVRSLEEDLKRRDFTVNALALDENGQVIDKFRGLIDLKQKRLRAVGKAEERFEEDA
                     LRIMRGFRFAASLDFDIEAATFEAMRSHSPLLEKISVERSFTEFDKLLMAPHWRKGIS
                     AMIACQAYDYLPGLKQQEAGLNHLIVSLKDNFTFSDHHQAWAYVMISLAIEDPKSFLK
                     AWKTSNDFQRYVTKLIALYRIRQERSFEKLDIYQYGKEMASLVEDLRKAQSLSVDMDR
                     INTLDQALVIHDKHDIVLNGSHLIKDFGMKPGPQLGLMLEKVELAIVEGRLDNDFTTI
                     EAFVREELAP"
     gene            22863..24740
                     /locus_tag="ACF4ZO_001261"
     CDS             22863..24740
                     /locus_tag="ACF4ZO_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HFD5486796.1"
                     /translation="MSHFLVEKLTKTVGDKTVFQDISFIIHDFDRIGIIGVNGTGKTT
                     LLDVLSGRLGFDGDHSPFSKANDYKIAYLTQDPEFNDAASVLDTVLSSDVKAIQLIRQ
                     YELLMANYTEDKQETLESLMSEMDRLDAWSIESDVKTVLSKLGITDLEQKVGDLSGGM
                     RRRVQLAQVLLGAADLLLLDEPTNHLDIDTIAWLTTYLKTAKKTVLFITHDRYFLDHV
                     ATRIFELDKAGLTEYQGNYQDYVRLKAEQDERDAANLHKKKQLYKQELAWMRTQPQAR
                     ATKQQARINRFTDLKKEVHQDSSADKLEMAFETSRIGKKVIHFEDLSFAYGDRQLIKD
                     FNLIIQNKDRIGIVGDNGVGKSTLLNIINGDLKPTSGKLDIGDTIRVGYFSQQLKDMD
                     ETKRVINYLQEVADEVKTSVGTTSISELLEQFLFPRSSHGTLIAKLSGGEKKRLYLLK
                     LLIEKPNVLLLDEPTNDLDIATLTVLENFLANFAGPVITVSHDRYFLDKVATKILAFE
                     EGDIRVFYGNYSDYLDEKAFEKETVEADLAKAIVTEEVPLPPKEEKKRMSYLEKQEWA
                     QIEDKIATIEANIEEIENQMLTVVSDYGQLAQLQKELDQRNNDLLLAYERFEYLSGLD
                     I"
BASE COUNT         8012 a         3991 c         5043 g         7752 t
ORIGIN      
        1 agcccttgaa ggtgctaaga aagcaggaag tgattatgta gaactggatc taatcttgac
       61 taaggataat cactttgtgg tgtctcatga taatcgattg aagcgtttag ctggagtaaa
      121 taagacgatt cgcaacttaa ccttaaaaga agttgaacat ctaacgagtc atcaaggaca
      181 tttttcaggg cgttttgttt cttttgacac tttttatcaa aaggctaaga agttgaatat
      241 gccattactt attgaactca agccaattgg cacagaacct ggaaattatg tcgatttgtt
      301 tttagaaact tatcatcgac ttggtataag caaagataat aaagtcatgt ctttagattt
      361 agaagtaata gaagctatca agaaaaaaaa tccatcaatt acgactggtt atatcatacc
      421 aattcaattt ggattttttg gagatgaatt tgttgatttc tatgtcattg aagacttttc
      481 ttatcggtct tatttgtcgt cccaagcttt ttggaataat aaagaaattt acgtttggac
      541 tattaatgat cccaagcgca tagagcatta tctcctaaag cctattcaag gaattattac
      601 agatcaacca gctttaacta atcaattgat taaagactta aaacaagata attcttattt
      661 tagtcgatta gtcagaatta ttagtagtct ttattaaagg tttaaggaaa gtgtcaagaa
      721 aaaaacttga cactttcctt aaactgagtt atactgttta acataggaat ttagcgtagc
      781 tgtatttctt atacattact aaaagaaaag agactattta aaaatggcag taaaaatccg
      841 tttaactcgt atgggttcta agaaaaaacc tttctaccgt attaatgttg cagattcacg
      901 tgcaccacgt gatggtcgtt ttatcgaaac agttggaaca tacaacccat tagtggctga
      961 aaatcaaatt actattaaag aggatcgtgt tcttgaatgg ttatctaaag gagcgcagcc
     1021 ttctgatacc gttcgtaaca tcttgtctaa agctggtgtt atggctaagt tccacgacca
     1081 aaaattctct aaataataac agcctatgga taccattgaa aatcttatta tcgctattgt
     1141 gaaacctttg atttcacaac cagataatct taccattaaa attgaagata ctcctgactt
     1201 tttagagtat catcttgact tggatgctca agacatcggt cgtgttatcg gcaaaaaagg
     1261 tcgaactatt actgcgataa gatcgattgt ctactcggtt ccaacactag gaaaaaaagt
     1321 tcgcttagtt attgatgaga aataatcact aacttgagat ggattgaaaa gcttgttgac
     1381 ttaaagtcaa caagcttttt gaatagcaaa aatcttaata tttctgaaat gaaaagatta
     1441 gatttttctg tctttagcta aaaagaagtt aaagaattgc ttagctgatt gcctttataa
     1501 gagattatac tggtttttga tagctgctgt catgtaaaat agctacaatt catcttacga
     1561 gattgacctt agcattgcca gtgcagtctt tattttccaa cctgctgttt gttgtatgtt
     1621 tatagtttcc taaaaaatgc tctctcagtt ttttgggggg aattcctaaa attaagtata
     1681 cttaattttg ggaatgttta tattctttac attctgatga aaatacaaat tatcctaaca
     1741 tgatgtattg aaaggggaaa tagtttatgt tagtatactg attaagtgaa gctgtaatga
     1801 gacttatact atcaaaaaag ttagaataac tttataaaac agtggtgttg aagcaagttt
     1861 agcttcttct cagaaataga ttatctataa aaaatcccaa aagtagtttg tttccagtta
     1921 atgaacttct tttgggaagg cttttttgct ggtcgccacc tcacttgtat atcgggaacc
     1981 ttcacgctaa gatgtataag ttgaatcgtt tgtctatggc ttgatgaaaa ttaatcaaaa
     2041 gataatgttc aactctataa ttggtacaag taaaatgaga taacttattc attagtaagc
     2101 ataagatata acaagagaaa ttaccttaaa acaggaagta ctagagtatt taaaataagt
     2161 gatagacttg gatattatta ggtcgactag tgtccttttc aataatttaa tatcgttatt
     2221 attagtatca gccaatcaaa tgtggataag ttggctttta gaaaggtttt accacaatga
     2281 agaaacatct taaaacagtt gccttgaccc tcactacagt atcggtagtc acccacaatc
     2341 aggaagtttt tagtttagtc aaagagccga ttcttaaaca aactcaagct tcttcatcga
     2401 tttctggcgc tgactacgca gaaagtagcg gtaaaagcaa gttaaagatt aatgaaactt
     2461 ctggccctgt tgatgataca gttactgact tattttcgga taaacgtact actcctgaaa
     2521 aaataaaaga taatcttgct aaaggtccga gagaacaaga gttaaaggca gtaacagaga
     2581 atacagaatc agaaaagcag atcaattctg gatctcaact agaacaatca aaagagtctc
     2641 tttctttaaa taaaagagtg ccatcaacgt ctaattggga gatttgtgat tttattacta
     2701 aggggaatac ccttgttggt ctttcaaaat caggtgttga aaagttatct caaactgatc
     2761 atctcgtatt gcctagtcaa gcagcagatg gaactcaatt gatacaagta gctagctttg
     2821 cttttactcc agataaaaag acggcaattg cagaatatac cagtagggct ggagaaaatg
     2881 gggaaataag ccaactagat gtggatggaa aagaaattat taacgaaggt gaggttttta
     2941 attcttatct actaaagaag gtaacaatcc caactggtta taaacatatt ggtcaagatg
     3001 cttttgtgga caataagaat attgctgagg ttaatcttcc tgaaagcctc gagactattt
     3061 ctgactatgc ttttgctcac ctagctttga aacagatcga tttgccagat aatttaaaag
     3121 cgattggaga attagctttt tttgataatc aaattacagg taaactttct ttgccacgtc
     3181 agttaatgcg attagcagaa cgtgctttta aatcaaacca tatcaaaaca attgagttta
     3241 gaggaaatag tctaaaagtg ataggggaag ctagttttca agataatgat ctgagtcaac
     3301 taatgctacc tgacggtctt gaaaaaatag aatcagaagc ttttacagga aatccaggag
     3361 atgatcacta caataaccgt gttgttttgt ggacaaaatc tggaaaaaat ccttatggtc
     3421 ttgctactga aaatacctat gttaatcctg ataagtcact atggcaggaa agtcctgaga
     3481 ttgattatac taaatggtta gaggaagatt ttacctatca aaaaaatagt gttacaggtt
     3541 tttcaagtaa aggcttacaa aaagtaaaac gtaataaaaa cttagaaatt ccaaaacagc
     3601 acaatggtgt tactattact gaaattggtg ataatgcttt tcgcaatgtt aattttcaaa
     3661 ataaaacttt acgtaaatat gatttggaag aagtaaagct tccctcaact attcggaaaa
     3721 taggtgcttt tgcttttcaa tctaataact tgaaatcttt tgaagcaagt gacgatttag
     3781 aagagattaa agagggagcc tttatgaata atcgtattga aaccttggaa ttaaaagata
     3841 aattagttac tattggtgat gcggctttcc atattaatca tatttatgcc attgttcttc
     3901 cagaatctgt acaagaaata gggcgttcag catttcggca aaatggtgca aataatctta
     3961 tttttatggg aagtaaggtt aagaccttag gtgagatggc atttttatca aatagacttg
     4021 aacatctgga tctttctgag caaaaacagt taacagagat tcctgttcaa gccttttcag
     4081 acaatgcctt gaaagaagta ttattaccag catcactgaa aacgattcga gaagaagcct
     4141 tcaaaaagaa tcatttaaaa caactggaag tggcatctgc cttgtcccat attgctttta
     4201 atgctttaga tgataatgat ggtgatgaac aatttgacaa taaagtggtt gttaaaacgc
     4261 atcataattc ctacgcacta gcagatggtg agcattttat cgttgatcca gataagttat
     4321 cttctacaat agtagacctt gaaaagattt taaaactaat cgaaggttta gattattcta
     4381 cattacgtca gactactcaa actcagttta gagacatgac tactgcaggt aaagcgttgt
     4441 tgtcaaaatc taacctccga caaggagaaa aacaaaaatt ccttcaagaa gcacaatttt
     4501 tccttggccg cgttgatttg gataaagcca tagctaaagc tgagaaggct ttagtgacca
     4561 agaaggcaac aaagaatggt cagttgcttg aaagaagtat taacaaagcg gtatcagctt
     4621 ataataatag cgctattaaa aaagctaatg ttaagcgctt ggaaaaagag ttagacttgc
     4681 taacaggatt agttgaggga aaaggaccat tagcgcaagc tacaatggta caaggagttt
     4741 atttattaaa gacgcctttg ccattgccag agtattatat cggattgaac gtttattttg
     4801 acaagtctgg aaaattgatt tatgcacttg atatgagtga tactattggc gagggacaaa
     4861 aagacgctta tggtaatcct atattaaatg ttgacgagga taatgaaggt tatcatgcct
     4921 tggcagttgc cactttagct gattatgagg ggctcgacat caaaacaatt ttaaatagta
     4981 agcttagtca attaacatct attcgtcagg taccgactgc agcctatcat agagccggta
     5041 ttttccaagc tatccaaaat gcagcggcag aagcagagca gttattgcct aaaccaggta
     5101 cgcactctga gaaatcaagc tcaagtgaat ctgctaactc taaagataga ggattgcaat
     5161 caaacccaaa aacgaataga ggacgacact ctgcaatatt gcctaggaca gggtcaaaag
     5221 gcagctttgt ctatggaatc ttaggttaca ctagcgttgc tttactgtca ctaataactg
     5281 ctataaaaaa gaaaaaatat taaattgatt taaggagaaa aaatgataac acaagaaatg
     5341 aaagatctta ttaataacca attagcaatg gttgcgacgg ttgatgccaa aggtcaaccc
     5401 aatattggtc caaaacgttc tatgcgtctc tgggatgata aaacatttat ttataatgaa
     5461 aatacagatg gtcaaactcg tattaacatt gaagataatg ggaaaattga aattgccttt
     5521 gttgatcgtg agcgcctttt aggttacagg tttgtaggaa ctgctgaaat tcaaacagaa
     5581 ggtgcttatt acgaagcagc gaaaaaatgg gcacaaggac gcatgggggt accaaaagca
     5641 gttggtatta ttcatgtcga gcgtattttt aatttacaat ctggtgctaa tgcaggtaaa
     5701 gaaataaaca gtgaaagtaa ctaaaattaa ctgtaacagt atttaggacc cttattttaa
     5761 acgctaaaaa acaagcatac tcttttttac agcatagtga ctatgttgta aaaaggggta
     5821 tgcttattag gtactcttaa tatttataga taactgcacc taataagttt tcaatagacc
     5881 tatagcacat taattgactt caattagttg acttcaatac tagaaagaga agaacagtga
     5941 tgttggtgtt cgtttaaaga agtatcgatt tccacagtga ctgagtttat attgtacctt
     6001 tgacaaatca gtctaataga ttttttgcaa tgtttttcag tggtagattc tctcaagcag
     6061 caatgtatag ttgctctatg atcaatacca tccatcgacc aaacattaag ctgattaaca
     6121 gacactatat gaggaagttg gctgagttca tggtgcaaag cgcaatagtc tatcgaatca
     6181 ggaacaccat ctaaaaaaat gttagcagtt gctactaact ttggaagagc tttagataat
     6241 ataaaagaag caatggcaat tgataataaa ggatcaagaa tgtaccaagg tttccatttt
     6301 aagatcagtg acagtatgat aatggctaac cacccaagga tatcttctaa aaagtgaagg
     6361 cttaatattt cttcattttt tgtctggtta gagtgaatga tgaagctagc aaatccattg
     6421 attataattg caaaaatagc taaaacgaac ataccgtcat aattaacaat agtaggatgc
     6481 cataattttg gtatcgtttc aatcattact aataatgacc cgctaataag tattagattt
     6541 gttgttagtg ctcctaaaag gctaaatcgc ttatagccta gtgaaaaatt tgaactctct
     6601 tttttaacag cctttctttc taagatagct gagataccaa tagcaatggc atctccaaaa
     6661 tcgtggacag catctgctaa aatagcaccc gaaaagaata atgtcccaaa aataaattca
     6721 atgagggaaa aactaagatt taatataaaa ataatgatga cttttttact tgctggcata
     6781 attttctcct tttgttatac tggtaatatg tatagtagaa ttctttattc tattatctaa
     6841 aagttaaaat acaattacta taaccaaaaa tgagcacctg ttcaatagtg aacaacattt
     6901 agaaagtgtc cgatatgaca aaagacagac aaatcaaaaa aacaaaaaca gctatctata
     6961 gtgcttttct tgctttatta caaaaaaaag aatattcgaa aataactgtt cgagatatga
     7021 ttgcacttgc taatgtaggg agatcaacct tttatgcaca ttatgaaagc aaagaaatgt
     7081 tactaaaaga actctgtgaa gaactttttc atcatttgtt taggcaaaaa agaaatgtga
     7141 cttttgagga ctatttggta catattttaa agcattttga acaaaataaa gacagcattg
     7201 cgacgttgtt actttctaat gatccctatt ttttattaag atttaaaaac gaactagaac
     7261 atgatgttta ccctaacttg cgctgcaagt atatcgacaa aacgactatt ccagaagtat
     7321 tcctgaaaca atttgttcta tctagtttta tagaaacctt aaaatggtgg ctccatcaaa
     7381 ggcaaaggat gtctgcaaat gaactattaa agtattattt agagctcata aaataatgac
     7441 tagtgagtca tcttgccaaa ttcaattttt taatacagac ggattttaac aatttaacag
     7501 agaaagacaa aactgtaagt gcaaaataga ctataacgtg ataaaataat aggtaatttg
     7561 gttctgaaaa agaagtgtct atcaaacttt agaatcaaga gaggtcgcta aagtgacgtg
     7621 agataaagag ttaacgattt aggagctacc atggaatatt ttaatgttgg aaaaattgtc
     7681 aacacgcaag gcctgcaagg agagatgcgc gtgttgtctg tcagtgattt tgctgaggag
     7741 cgctttaaga agggatcgca attggctttg tttgatgaca aagaccagtt tgttcaagag
     7801 gtcacgattg ttagccatag aaagcaaaaa aactttgata tcatcaaatt taaagacatg
     7861 tatcatatta atgcgattga aaaatataag ggctatacgt taaaagtgtc aaaagctaat
     7921 caaggagacc tgcaagaagg agaattttac taccatcaga ttatcggtat ggctgtttat
     7981 gaaaaggacc ggttgattgg ctatgtcaag gaaatcttgc agccaggtgc taatgatgtt
     8041 tgggtagtga aacgccaagg aaaacgagac ttgctcttac catatattcc cccagtagtt
     8101 cttagcgtag atgttcctaa caagcgcgta gatgttgaat tgatggaagg cttagacgat
     8161 gaagattgat attttaaccc tttttcctga aatgtttgcc cccctagaac attccattgt
     8221 aggcaaagca aaagaaaaag gattacttga cattcactac cataactttc gagattatgc
     8281 tgaaaaagct cgtcatgtgg atgacgaacc ctatggtggg ggccaaggca tgttattgag
     8341 agcgcagccc atttttgaca ccattgaaca gattgaagcc aaaaaaccaa ggattattct
     8401 tttagatcca gcaggtaaac cctttactca ggcttatgct gaagaattag ctcttgagga
     8461 agagttaatt tttatttgtg gtcattatga aggttatgat gagcggatta agaccttggt
     8521 gacggatgaa atttcattag gtgactttgt attaacagga ggtgagttgg cggccatgac
     8581 tatagtggat gcgaccgtca ggttaattcc acaggtactt gggaaagaaa gtagccatca
     8641 ggacgattct ttttcatcag gacttttaga ataccctcaa tacacaagac cttatgatta
     8701 tcgtggtatg acagttccag atgttctaat gagtggtcat cacgaacgta ttcgcttgtg
     8761 gcgtctagaa gaaagtctca gaaaaaccta tttgagaagg ccagatttgt tagagcggta
     8821 cgatttttcc gaggaagagc gcaagctatt ggataagatt aaagaagcat tgggttaagg
     8881 agaagattag tgaaagataa agcatatgat attacgatta ttggtggtgg tccaataggt
     8941 ttatttgcag ccttttatgc aggtcttagg ggcgtaacag taaagattat tgagagtttg
     9001 tcagaacttg gtggacagcc tgccattctt tatcctgaga aaatgattta tgatattcca
     9061 gcttatccat ctttaacagg tgttgagttg acagaaaatt taataaaaca attaagccgt
     9121 tttgaagatc gtacaaccat ttgtttaaaa gaagaagtat taacctttga caaggttaaa
     9181 ggtggttttt cgattaggac taataaggca gagcattttt caaaagccat tatcattgct
     9241 tgtggaaatg gcgcttttgc accaagaact ttagggttag aaagtgagga aaactttgct
     9301 gatcataacc ttttttataa tgttcaccag ttggaccagt ttgcgggaca aaaagttgtg
     9361 atttgtggtg gtggagattc agcagttgat tgggctttgg ctttagaaga tattgctgag
     9421 agtgtgacgg ttgtgcaccg tcgtgatgct ttcagagcac atgaacacag tgtggaatta
     9481 ttgaaaacat caacggtaaa cctcttaaca ccttatgtgc caaaagcatt gaaaggaatt
     9541 ggaaacctgg ctgaaaaatt agttattcaa aaagtgaaag aagatgaagt gttagaactt
     9601 gaattggaca gtcttattgt tagttttggt ttttcaactt ctaataagaa tttgaaaaat
     9661 tggaatctcg actataagcg ttcaagtatt actgtttcac cactttttca aacaagtcaa
     9721 gaaggtattt ttgccattgg tgatgcagcc gcttataatg ggaaagtgga tttgattgct
     9781 actggttttg gcgaagcacc aacagcagtt aatcaggcca ttaactatat ttatccagat
     9841 cgagataacc gtgtggtgca ttcaacctct ttaattgact aagggagtcg gaagtttcaa
     9901 gagcagtagc aacagctaat attcagtttg tcaggagagg acaaatggtt tttacctaag
     9961 tcttcgtgac aagttttata ctttgtgata aaatagtcat tgtgaaaaaa gtgtgatggt
    10021 tttcacagat taacacatta caatgaaaag gggtctatca tgacaacaac agataaagag
    10081 acatttagtt cttttatgaa taagatcttg gctggtacag cgattgctat cgttgtggca
    10141 ctcattccaa atgctatttt agcgactttc ttaaaaccgc ttttgccaaa catggcagct
    10201 actgaatttt tacacattgt gcaagtcttc caattcttca cgccgattat ggctggtttc
    10261 ttgattgggc aacaatttaa gtttaatcct atgcaacagt tggctgttgg tggagctgct
    10321 tatatcggtt ctggggcttg ggcttataca gaagtcattc aaaaaggtgt ggcgacagga
    10381 acattccaac ttagaggtat tggggactta atcaatatga tgattacagc tagccttgcg
    10441 gttttagctg tgaaatattt tgggaataga tttggctctt taaccattat cttgttacct
    10501 atcactatag gaactggcgt aggttatatt ggttggaaat ttttgcctta tgtgtcttac
    10561 gtgacaaccc tgatcggaca agggattaat tcttttacaa ccttacaacc tattttaatg
    10621 tctattttaa ttgcagttgc tttctcgctt atcattgtta gtccgatttc aactgttgca
    10681 atcggtttag ctattgggct taatggaatg gctgcgggag cagcttctat gggaattgca
    10741 tcgacagcag cagtcttagt gtgggcgacg cttaaagtta ataaatctgg tgtaccaatt
    10801 gctatcgcac ttggggctat gaaaatgatg atgccaaact tcttgaaaca tcctatcatg
    10861 gctattccga tggtgttcac tgcagcaatt agctcattaa cagtaccatt gtttaatctt
    10921 gttggaacac cagcttcatc tggttttggc ttagttggtg cagtaggtcc gattgcttct
    10981 ttagcaggtg gtagctcaat acttattatt atccttgctt ggatcattgt tccgtttgcg
    11041 gttgcttttg cggcgcataa ggtttctaaa gatattctaa aactttataa agaagacatt
    11101 ttcgtctttg aaggctaata ggaggaaaat atgttagttt atattgctgg ctcaggagcc
    11161 atggggtgcc gttttggtta ccaaatttca aaaacaaata acgatgtgat tttgttagat
    11221 aactgggaag atcatatcaa tgccattaaa gaaaacggtt tagtggtgac aggggatgtg
    11281 gaagaaacag ttaagcttcc tattatgaaa ccgactgaag ccactcaaga agccgatttg
    11341 attatcttgt ttacaaaagc aatgcagttg ccacaaatgc ttcaagacat taaaggcatt
    11401 attggaaaag aaaccaaagt gctttgcctt ttaaatggtc ttggacacga agacgttatt
    11461 cgtcagtaca ttccagagca caacattttg atgggggtca ctgtctggac tgctggtcta
    11521 gaaggacctg gtcgtgctca tcttcaagga gttggtgctc ttaacttaca aagtatggat
    11581 ccaaacaatc aagatgcggg acatcaagtg gctgacttgc taaataaagc taacttaaat
    11641 gcgacttatg atgagaatgt tgtgccaaac atctggcgga aagcttgcgt gaatggtacc
    11701 atgaattcga cttgtgctct tttagattgt acgattggcg aattatttgc cagtgaagat
    11761 ggtctcaaaa tggtaaaaga aatcatccat gagtttgtta tcgttggtca agcagaaggt
    11821 gtcgaactaa acgaagaaga aatcacacaa tatgtaatgg atacatctgt tagagctgct
    11881 caccattacc catcaatgca ccaagacctt gtgcaaaatc accgattgac tgaaattgat
    11941 tttatcaatg gtgcagtcaa taccaaaggt gaaaagcttg gtatcaatac tccatactgc
    12001 cgtatgatta cagagctagt tcacgctaaa gaagcagtgt tgaacatcca ataaacgcta
    12061 tcaaatcgtt atactcaata ttatagctaa agctttaata ttgagttttt tgttatgctg
    12121 atagtatttt tcttaggcgt cattatttgt gagcctagat tatgagttaa taaaagaaat
    12181 aataattggt agaatttgat agattttgaa aggttatgct tgacttttag ttataaaata
    12241 gtataataat tgtaaacgat ttcagttagg ggtggttcta tcttaaaatc aaaacgaaaa
    12301 caattaatca tggcaaagat cactgaagaa aactatgttt ctttagagga tttaatgcaa
    12361 ttactcaact cctctgagtc tactatccgt agagatctag gagagttgga gcaagaagga
    12421 cggctacatc gtgttcatgg aggtgctgaa ctttttcact ctttacaaga ggaactttcg
    12481 aaccaagaaa agtctgtcaa aaacagtcat attaaaaaaa ctattgcgca aagagcctct
    12541 cagtttatct atgacaacga tgtgatcttt attgatgctg ggacaacgac tgaattttta
    12601 ttaccttttt tacaagctaa aaatttaact gtagttacta attctattca tcatgctgct
    12661 agattagttg aactctctat tgagacgatt attgtaggtg gttatgtcaa acaaacgacc
    12721 gatgccagta ttggtaatgt agctttggaa cagattaggc agatgaattt tgacaaggca
    12781 tttcttggaa tgaatggtat tgatgattct tacctgacga ctcctgatat ggaagaagca
    12841 gttattaaaa aagcggttct gtcaaatgca aaattagctt acattttagt agatggcact
    12901 aaaattggtc aggtatcgtt tgtaaaagta gctcctatta atgatgtgac tattattaca
    12961 ttaggaggat cagcaagtat tcttaaacaa ataaaggaaa aggcaaaggt gattgaatta
    13021 tgatttatac cgtgacctta aacccttcta ttgactttat tgtcagaatt gaccaaataa
    13081 atcttgggtc agtgaatcgc atggcgagtg atgataagtt tgctggaggt aaaggcatta
    13141 atgtgagtcg catcttgcaa cgtttagaca ttgctagcac ggcgacagga ttcttgggtg
    13201 gttttacagg acgttttatc gaagaaagtt tgagtgcaga aggcgttaaa actgattttg
    13261 taaaaggtga tcaagatact cgaatcaatg ttaaaatcaa gtcacaagaa gagactgaaa
    13321 taaatggtca aggacctgtc attagtcggg aacaactaga ggatttgaaa actaagcttt
    13381 cccagctaac agcagaggat acagttgtct ttgcaggttc agcgccagct aatcttggca
    13441 atgctgttta taaggaatta cttcctttag ttaggcaaag cggtgctcag gtggtttgtg
    13501 attttgaagg acagacttta atagatgcgc ttacatataa tcctctgttg gttaaaccta
    13561 ataatcatga actagaagct atttttggta cgattctgac tagtcttgat gatgttgaaa
    13621 cctatgcccg tcgtctttta gagatgggtg ctcaaaacgt catcatttca atggctggtg
    13681 atggtgcttt gctggttact aaagaagcga cttattttgc taaaccgatt aagggagaag
    13741 ttaaaaattc tgtcggtgct ggtgattcga tggttgctgg ctttacaggc gaatttatga
    13801 agagtcaaaa tccaatagaa gccttaaaat ggggcgtggc ttgtggtaca gcgacggctt
    13861 tctctgatga cttggcgaca attgcattta ttaaggaaac atatcataaa gttgaggtag
    13921 aaaaacgatg aaaattcaag atttattgag aaaagatatt atgattctcg atttacaggc
    13981 tatttctaaa gaagttgcca ttgacgagat gattactaaa ttagttgaaa aagatattgt
    14041 acatgatttt gatgtcttta aaaagagtat catgacacgt gaagaacaaa catcaacagg
    14101 gcttggtgat gggattgcca tgcctcattc taaaaatatt gtagtagata aaccagcggt
    14161 cttgtttgcg aaatcaaata aaggtgtgga ttataaggct ttagatggtc aaccaacgga
    14221 tctcttcttt atgattgctg cgcctcaagg agcaaatgat actcacttgg ctgcgctagc
    14281 agaattatca caataccttt tgaaagacgg ctttgctgat aaacttcgtg ctgcagcgac
    14341 accagaagca gtcattgctg tttttgatga agcgtcaaca gctaaagaag aagtggttgc
    14401 tccaacaagt ggtcaagact ttatcgttgc tgttacagct tgtccgacag gaattgctca
    14461 cacttatatg gcagaagagg ctttgaaaaa acaagctgca gaaatgggag tagctattaa
    14521 agttgaaaca aacggtgctt ctggtgtggc taatcgttta accgctgaag atattcagag
    14581 agctaaagga gttattgttg cagctgataa agcggttgaa atggaccgtt ttgatggtaa
    14641 acaattcatt gctcgccctg ttgcagatgg tatcaagaaa agtcaggaat tgatttcttt
    14701 gattttgaat aatgaaggac acacttacca cgctaagaac agaaagtctg aaacagcagt
    14761 atcatctgag aaaacaagct taggcggtgc tttctataaa cacttgatgg gtggtgtctc
    14821 acaaatgttg ccatttgtta ttggtggcgg gattatgatt gctctagcat ttttattgga
    14881 taacatgctt ggtgtgccaa atgatcagct tggaagtctt ggatcctatc atgaaatagc
    14941 agctattttt atgaacattg gtggagcagc cttttccttc atgttaccag tactagcagg
    15001 ttatatcgct tattctattg ctgaaaaacc gggcttagta gctggttttg tggcaggtgc
    15061 cattgcctca agtggtcttg cttttggtaa ggtaccattt gcagcaggag gagaagtgag
    15121 cttgggatta acgggcgtgc catcaggttt ccttgggacg cttgtgggtg gtttccttgc
    15181 cggtggtgtt attcttgccc ttcgtaaatt gttggcaggc ctaccacgtt ctctagaagg
    15241 ggttaaatct atcctccttt acccattact tggcgtcctt gtcactggtt tcttgatgct
    15301 ttttgtcaat attccaatgg cagctattaa cacagctctt aatgatttct tacaaggtct
    15361 ttcaggaagc tctgctgtcc ttatgggact tcttgttggt ggaatgatgg ctgttgacat
    15421 gggtggtcct gttaataagg cagcttatgt ttttggtaca ggaactttag cagctactgt
    15481 ggcaaatggt ggttcggtcg ttatggccgc tgttatggca ggtggtatgg tacctcctct
    15541 tgctgttttt gtagccactc tcttgtttaa agataaattt accaaagaag aacgcgaatc
    15601 aggtttgacc aacattgtca tgggactttc tttcatcact gaaggagcaa tcccgtttgg
    15661 cgcagctgac ccagcgcgtg caattcctag ctttattgct ggttctgcct tgacaggagc
    15721 tcttgttggt ttggctggca ttaaattaat ggcgccacat ggtggtatct tcgtaatcgc
    15781 tttaacaagc aatccaatct tatatcttgt ctttgttgtg attggtgccc ttgtatcagg
    15841 tatcttattt ggcgctcttc gcaaaaaagc ctaaaaggta aagaactttt ttcttactaa
    15901 aactagaatc tgtcaaggtt ctagtttttt gctatactag agttaaagga taagaaatga
    15961 ggacctttga aggtgaaaaa aaggagaaga agggctaaat catccgtaaa tcgacttgtc
    16021 ttagggttag tattacttaa tctgattgtt agtatgtgga cattaaaatt gggaaaccag
    16081 cgattagctc cgtatgcgga tcacgaaact ctgacatttg tcaggaagat tagtcatgct
    16141 gctcaatcag tcgctcaaaa gaaacagtta tacagttcgg tgatgatggc tcaggccatt
    16201 ttagaatcca ataatggcaa gtcacaacta agtcaaaaac cttattataa ttttttcggg
    16261 attaagggga gctataaaga acggtcagtc atttttccaa ctttagaaga cgatggacaa
    16321 gggaatcttt atcaaattga tgctgctttt cgttcctatg ggagcctgac agcttgtttt
    16381 ttagattacg caagagtttt gaatgatcca ctttatgaca aaacccacaa aaagttttgg
    16441 tctcattatc aagatgctac tgcaacctta acaggcactt acgccactga tacaacttac
    16501 cataccaaat taaatgaatt gattgaatgg tatcaactca ctaattttga tggtctaatg
    16561 aaatagttat ccacaatttt aaaaaaaaat cagaagaaat atgtcgattt caagacaaaa
    16621 gttatcaatc tcattaaatt atctgtggaa aagttaattt aaacgttcgt gtgctataat
    16681 agaaacatag aaaatgtata aaaaaggata tgtgaataat gacaaaaaag aaaggtaagc
    16741 ttgtacttat cagtcttttt gttctagcag cttgtttagg agcttatagt gcaatgagac
    16801 aatctcataa aacttcaaac gtgtcagctg agactatcgc cagttcttca acccgacatt
    16861 ttattgatga aattggtcca actgctagta ctattggtca agaacgtgat ctttatgcgt
    16921 ctgttatgat agcacaagcg attttagaat caagtaatgg taaatcaagt ctaagtcaag
    16981 caccttatta taattttttc ggtattaagg gtgcctataa cggttcttct gtgacgatgt
    17041 caacttggga agatgatggt aatggcaata cctatacgat tgatcaagcc tttagagctt
    17101 atccaagtat tgcagactcc cttaatgact atgcagactt gctaagttct agcacttata
    17161 taggtgctag aaaatcaaac acgctatcgt atcaagatgc tacagcagct ctaactggct
    17221 tatacgctac agacaccagt tataacttaa aactaaataa tattattgca acctatggtt
    17281 tgacggctta tgatgttgct aatagctcag ctcaagaaac gggtctagca acttcgggtt
    17341 atgtttggaa tgagtatcgt cgtaattaca ctgatgcgga gaccctagca gttgatgagg
    17401 cttgggctaa acgcatgact tattaatgta acactaacaa caatctgctt gcactgaccc
    17461 caaaaaagct ggatactcta ttttaaataa aggatttagt tctgtacaat acagaactaa
    17521 atccttttag ttttactttg atatgtttat cgttgtaata atcaatgtca tttgtaatcg
    17581 cttattctga gtcttctagt gatttatagt tattctcata accatagaac atttctgact
    17641 ttaagatgcc aaagaaagat tccataatgc cattgtcagg actgtttctt ttacgtgaca
    17701 tagacggacg aattccttta gagtttagga aatgatgata atagttgtgt tgatattgtc
    17761 aaccttgatc actctatcat atagttccgt catagcattt atttggagat gcctttttcc
    17821 attattgatt taatgtgatt taagcaaggt tattagctaa acttaatgcc agacaaaaac
    17881 accccaatta ttagattttt tgtctaactt ttggggcgca attcaatctg agcagtttta
    17941 gatttggtat caatgttatt ataggtcaat tgatcatatt tatccaaagc ttttagctta
    18001 tttagtccaa agataaatat caaaatggct gaaatctttc atgtttatag tcttattgtc
    18061 tttatatttt ttaaagacat cagatctggt gctattgggt tttgcgtcat ataaattgat
    18121 tttttcatgt ttcctatttt tactgtgaat ttctaaactc ccccttatat aaggagactt
    18181 agtcaaataa atttcttttg attccatcaa aaattttctt attttaaaat cgaactcttg
    18241 aatagtaaca atgtccttat cgatttttat aggatttatt aatgtttttt gctgttgccc
    18301 atctataaaa aaattccctg caatagtatt agtccttaga ataccatcat ctgttgaagg
    18361 taatctttct tattgatacg ctttaattgg tctgattcca actatcttgc cctgttgaaa
    18421 gtgtaaataa ccctagtact tgagcaccaa tattatcttc ttttatttct ttagcagaaa
    18481 tagctacttt tccagcggaa ttaacaccaa caaagtattt cttcatacca atagatgcat
    18541 tactatcaga gtctgttaca taaatagctt caaggttccc gttagaatcg aagtcagctc
    18601 cccacaggtt tataacatgg ttgatgcgta cgttagcgta ggtgtgtgat aggcctagag
    18661 ccttgtcttt cttaatgaga tcactgattt ctttgagagt tttttcttta aaatcatgac
    18721 gacttgtcaa tagcttactt tgatcacctc ttgtaaatac ggcgtcaaaa ataccacctc
    18781 ggcgatcttt ctcttgatag gttctattga catcagtagt ctgtgtctta taaacattta
    18841 agtaataacc attgataaac atatctaaaa caagatcagg cataactcca attcggcgtg
    18901 ctgacaaacc ggggaaagct ttatctcgga aataattaaa aagctcgcta tttgtttggt
    18961 cacctttagt attaataact tttcttacat ccaataattc ttgatcacca aacatgattt
    19021 tttgtttatc tgggtgtttt tttagatatg cttcaatttt ttcgttgttt tgatcgaacc
    19081 accagtgaag catattccct gctgtggcag ccccgcaaag aaggtcgtct tttccattga
    19141 atgttttggt aatatcatac catccttgtt tagcaacata aggagcgtga aaaacatctt
    19201 cgccttgagt gaattttgct ggaggagtaa ctcctttggt ccaaacggaa gtaacatgat
    19261 aaggtgttac ttccgaatat ctaatctctt gattagcaga aaaactatct gctataacac
    19321 cacgatctac cgatagagca aataaagtca ctgctgccaa tactacagct gaagttgaat
    19381 agcatctttt tctcataaga gtaccttttt ctatacaatt ttattataaa aagattatat
    19441 tatataggca tctattgttg caatttttta aaataatatt taatttttta aataattttt
    19501 aacaaactta aacaagcgat tgacaatgga gatatcacaa gagacacagt agtggttgtg
    19561 cttaaaaatg gacggttttt tgatgatatg ttgctgcatg aggaagtgag caataggaga
    19621 gctgtgatag aagaaagaag agaagaggcg ttgatgaaat tagacaaata aaaaaagacc
    19681 tcatccagaa gaggtcgtgg tataactggg ggacgatagg tttaattgat aaaaaatctt
    19741 gttagtttac gatctatgtt gttttgaatg cttttaactc aacatcgtta atggattttg
    19801 agataaaaaa ataaatccaa tagtctggta ctttcctatt ttttgtctgt taaaacgttt
    19861 ttattttata atggataaaa ggagaagaag ggcggagcga tgattaagcc cgatgggttt
    19921 aagtatgggt tagttggaga ggttttgcgg cggattgaac gcctaggatt tacgtttgag
    19981 cgactagagc taagacaagc tagttcgaaa tacttggcta agcatgatga ggccttaatg
    20041 ataaaccttt ttatccttga cttaaaactt acctgaccag tggttctgtt ttaattgagg
    20101 tgcagtacaa gaccgctaac gggtgttttt ttgatataat gtcagtataa ggacgactaa
    20161 atataaatag gtgaaaaaaa tagatatctg ttcgagagat agcactgttt aaaacgttat
    20221 gcgaaaatag tagtttaggg gctactttaa taatcttcaa atctatgcta taatggatca
    20281 tattgatacc aaggagaata aaaaatgcaa ttagttcgtg aaaaagaatt tgtcaatcaa
    20341 taccactatg atgctagaaa tttagagtgg gaaaaagaaa acggaacacc agagaccaat
    20401 tttgaagtga cttttcagtt gattgataaa gatgagcagc aaaaagaaac agtaattgta
    20461 tctgtattgc aatttgttat tgtcaaagaa gaatttgtta ttagtggggt catctcacaa
    20521 atggttcgca ttttagatcg tttagtggat aaaccaagcg aatttacgca agaggaagtt
    20581 gaatccttag ctgctccttt gctagacatg gttaagcgat tgacttatga agtcacagaa
    20641 attgccttgg atcgtccagg tattcatttg gagtttaaaa attaatgaaa ttagcagtaa
    20701 ttactgacag tacagcaaca ctaccaatag atctgaaaca agataaagct atttttagcc
    20761 ttgatatacc agttatcatt gacgatgaga cctattttga aggtcgaaat ttgagtatag
    20821 atgattttta tcaaaagatg gctgactccc aaaatcttcc caagacaagt cagccaagtt
    20881 tatctgaact agataatctt ttaggacttt tgtcttctaa gggttataca catgttattg
    20941 gcttgttctt agctggagga atctcaggct tttggcaaaa tattcaattt ttagctgaag
    21001 aacatcctga gattgaaatg gcatttccag acagtaagat cacatctgct cctttaggta
    21061 gtatggtaaa aaatgtgcta gattggtcac gtcaaggaat gacatttcaa gctattttaa
    21121 acaagctgca agaacagatt gataggacga cagcctttat tatggttgat gaccttaatc
    21181 atctggttaa aggcggacgc ctgtcaaatg ggtctgctct tcttggaaat cttttgagta
    21241 ttaaacctat tttacgcttt gatgaagagg gaaaaatcgt tgtttatgaa aaagtgagaa
    21301 cagaaaagaa agccatgaaa cgcttggttg agattttaaa tgacttgata gcagacggtc
    21361 agtataatgt gtctattatt cactcaaaag cacaagacaa agctgattat ttgaaacgac
    21421 tcttacaaga cagtggttat caatatgaca ttgaagaggt tcattttgga gcggtgattg
    21481 ctactcattt aggagaagga gccattgcat ttggcgtaac accgaggctt taattgtcga
    21541 ttagaaaaaa tagttaattg caagaatcac taaaacaata acaaaatgtg atagaaccca
    21601 agtagcctaa tcacacttta gattgggcta gttggatgat aggttagaaa acaacgtatg
    21661 aaattaatga caatgccttc tgagtttcag aaggctttac ccatattgac taaaataaaa
    21721 gaagctggtt atgaagccta ttttgtggga ggaagcgtca gagatgtttt actcgagcgt
    21781 cccattcatg atgtagatat tgcaactagt tcctatcctg aagagactaa agcgattttt
    21841 aacagaactg tcgatgttgg cattgaacat ggcactgttt tggttttgga aaatggtggt
    21901 gaatatgaaa ttacaacctt taggacagaa gatgtctatg ttgattatcg ccgtcctagt
    21961 caggtttctt ttgtgcgctc tttagaggaa gacttaaaac gaagagactt taccgtcaat
    22021 gccttggcct tggatgaaaa tggtcaagtt attgataaat ttagaggact cattgattta
    22081 aagcaaaaac ggttacgagc agtgggtaaa gcagaggaac gttttgaaga agatgcacta
    22141 cgcattatga gaggctttcg atttgcggcg agtctggatt ttgacattga agctgcaact
    22201 tttgaagcta tgaggagcca ttcacctcta ttggaaaaga tttctgtgga acgttctttt
    22261 actgaatttg ataaattatt gatggcaccg cactggcgaa aagggatttc tgccatgatt
    22321 gcttgtcagg cttatgacta tttaccaggc ttgaagcagc aggaagcagg cttgaatcat
    22381 ctgatagttt ctttgaaaga taactttacc tttagtgatc atcaccaagc ttgggcttat
    22441 gtgatgatta gtttagccat tgaggatcct aaaagcttcc taaaagcatg gaagacttca
    22501 aatgattttc agcgttatgt cacaaagttg attgctcttt atagaattcg tcaggaaaga
    22561 tcttttgaaa aattggatat ttaccagtac ggcaaggaaa tggcgagtct agtggaagac
    22621 ctccgaaaag ctcaaagctt atccgttgac atggatcgta ttaatacttt agatcaggca
    22681 ctggttattc atgacaaaca cgatatcgtc cttaatggtt ctcacctgat taaggatttt
    22741 gggatgaaac caggtcctca gctagggctt atgcttgaga aagttgaatt agcgattgta
    22801 gagggacgcc tagataatga tttcactaca attgaagcat ttgttagaga ggaattagca
    22861 ccatgagcca ttttttggtg gagaaattga caaaaacggt gggagataaa acagtctttc
    22921 aggatatttc ctttattatt catgactttg accgtattgg gattattggg gttaatggaa
    22981 caggaaaaac aactctttta gatgtcttgt cgggaaggct tggttttgac ggagaccatt
    23041 caccattttc taaagccaat gattacaaaa tcgcttactt aacacaagat cctgaattta
    23101 acgatgcagc ctctgtttta gatacggtat tgtcatctga tgttaaggcg attcagctga
    23161 ttcgtcagta tgaactattg atggcgaatt atactgaaga taaacaagag accttagagt
    23221 ccctcatgtc tgaaatggat cgcttagatg cttggtctat tgaaagtgat gtcaaaacag
    23281 tcctatcaaa attaggcatc acggatttgg aacaaaaagt gggagatcta tcaggtggta
    23341 tgagaagacg tgtccagcta gctcaagtat tgctaggagc tgctgactta ctcctattag
    23401 atgagccgac caaccatctc gatattgata ccatcgcttg gttaacaacc tatctcaaga
    23461 cagctaaaaa aaccgtcctt tttattaccc atgaccgtta tttccttgat catgtggcta
    23521 cccgtatttt tgaattggat aaagctggac tgacagaata tcaaggcaat taccaagact
    23581 atgtgcgctt aaaagcagaa caagacgaac gagatgctgc taatttacac aagaagaagc
    23641 aactctataa acaagaatta gcctggatga ggacgcagcc acaggcgcgt gcaaccaaac
    23701 agcaggctag aatcaatcgt ttcactgact tgaaaaaaga agttcaccaa gacagttctg
    23761 cggataagtt ggagatggct ttcgaaacga gccgaattgg gaagaaggtg attcactttg
    23821 aagacctttc ttttgcttat ggcgaccgac agttgattaa ggattttaat ttgattattc
    23881 aaaataaaga tcgtattgga attgttggag ataacggcgt cggaaaatct accctgttaa
    23941 atatcatcaa cggtgatctc aaaccaactt ctgggaagct tgatattgga gatactattc
    24001 gtgtaggtta tttctctcag cagctcaaag atatggatga gaccaaacgg gtcattaatt
    24061 accttcaaga agtggctgat gaggttaaaa caagcgtggg aacaacgagt atcagtgagc
    24121 ttttagaaca atttcttttt ccgagatcaa gtcatggcac gctgattgct aaattatctg
    24181 gtggggagaa aaaacggctc tacttgctaa aactgctcat tgaaaagcca aatgttcttc
    24241 tccttgatga gccaacaaat gatttagaca ttgccacctt gacggtctta gaaaactttt
    24301 tagctaactt tgcaggacca gtcattacgg ttagtcacga tcgttatttc ctagacaaag
    24361 tagccactaa gattttagcc tttgaagaag gtgatattcg tgttttttat gggaattaca
    24421 gtgattacct tgatgaaaaa gcttttgaaa aagaaacagt tgaggctgac ttagctaaag
    24481 caatagtcac tgaagaagtg ccacttcctc cgaaagagga gaaaaagcgc atgtcctacc
    24541 ttgaaaaaca agaatgggct cagatagaag ataaaatagc aactattgag gctaatattg
    24601 aagaaattga aaaccaaatg ttaactgtag ttagtgatta tggccagtta gctcaattac
    24661 aaaaggaact cgatcagcgc aataatgatt tattattggc gtatgaacgg tttgagtatt
    24721 tgagtggact agacatataa gtatactatg gtaatgttat gtttataata aacaagtgat
    24781 aatagaaaag aagtgctc
//
LOCUS       DAXMQE010000026        24545 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.026, whole genome shotgun sequence.
ACCESSION   DAXMQE010000026 DAXMQE010000000
VERSION     DAXMQE010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24545)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24545)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24545
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.026"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            complement(<1..2199)
                     /locus_tag="ACF4ZO_001262"
     CDS             complement(<1..2199)
                     /locus_tag="ACF4ZO_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adhesin"
                     /protein_id="HFD5486797.1"
                     /translation="MKQQTTNNKQQTTKSKIAKYAMVAALSSSILFSKVDLAKAKENL
                     EVNSTKIDDKAKIEIIKKEIAQMEKELSEKINKRERLLKEKSEISDKLSKENERLNKE
                     IKTLNNKIKELESKQEENKKMLEFFKEKLQKANGEKETLAKDLKEKDEMIDELKKLDS
                     ASKQSIEDALTAEKQKEKESSEKVTELKANLESAKKDLEKKEADYVKENALVERDKKD
                     LEKFEKEIAKAREKKQTTEKAIKDINASKHDLIDKDKKLKEKLETNKTSTKTLQTAYD
                     KAKKNLEEKRTELEKLNKQYPPHGPALDQKLEEIEKEIKALEDEMKGLENTQKELEAQ
                     KQTNSQMITEKGKEVLKLDGEIGGEQGKLEEAKRKIQDFNFALKEAQDAKQRYEQAKE
                     EGTVKPDEDPGFDQIIETIKKDIQSKEQEKAGIGTKITELTGKKEKAQQEKAGLESKN
                     RELDKQIQEKKSKVDEIKTKIGPKQQESQEIEKKIQNNIPQDVETRIEKLKEEIKTEE
                     NKVKGGEIVLLTQEREKANLEKLIKENQEKLEKLERLLAEKAKLEKEIQGLEGEIEDT
                     NKSKPQFEKQAEEAKKARDTQKELVKKAKKDLSEEEEKLKNIQNTIKEKQNKLKGLDN
                     KDQAIKDLEEEKAKIQENIDANKKEIEELEQEKNASKALSEKTANEIKTLKEKLLKLE
                     EEQKAEDEKVKELKEKIKKIDEKINGLDLEINNLKAEINKKRQMLAALEQK"
     gene            2619..3035
                     /locus_tag="ACF4ZO_001263"
                     /pseudo
     CDS             2619..3035
                     /locus_tag="ACF4ZO_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987985.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS982-like element ISSpy2 family transposase"
     gene            complement(3032..4585)
                     /locus_tag="ACF4ZO_001264"
                     /pseudo
     CDS             complement(3032..4585)
                     /locus_tag="ACF4ZO_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989173.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ComEC/Rec2 family competence protein"
     gene            complement(4566..5228)
                     /locus_tag="ACF4ZO_001265"
     CDS             complement(4566..5228)
                     /locus_tag="ACF4ZO_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HFD5486798.1"
                     /translation="MLDELLIKGKSFLRERYFLPYLISLLLGLFLILSFSFLFWGNKQ
                     SKAAVPALREISPVKQQVSEEKKEIQEDSSILVDLKGAVQKEGVYKLTASSRVRDVIE
                     LAGGLTSEADKHAINFAEKLTDEQVVYVPKQGEEISVLPRSLVSGKKETASKDQSKVH
                     INKASLEELQHIPGIGAKRAQDIIDMRDKLGGFKALEDLRQASGIGEKTLEKLKDDIF
                     LD"
     gene            complement(5427..6167)
                     /locus_tag="ACF4ZO_001266"
     CDS             complement(5427..6167)
                     /locus_tag="ACF4ZO_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipid acyltransferase family protein"
                     /protein_id="HFD5486799.1"
                     /translation="MFYAYLRGLVVFLLWVVNGNAHYHHEEKMLDASENYILVAPHRT
                     FWDPVYMAFAARPKQFIFMAKKELFANRLFAWWIKMCGAFPIDRDKPSPDAIRYPVNM
                     LKKSNRSLLMFPSGSRHSQEVKGGVAVIAKMAKVKIMPAAYQGPMSVKGLLAGERVDM
                     TFGNPIDVSDIKRMNDEGIAEVANRIQAEFDRMDDELAPFQPGKARNPLTYLYRLPLG
                     LVLVAVLLLTMLFSYIASFVWNPDKHRH"
     gene            6285..7061
                     /locus_tag="ACF4ZO_001267"
     CDS             6285..7061
                     /locus_tag="ACF4ZO_001267"
                     /EC_number="2.1.1.223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016430 - tRNA
                     (adenine-N6)-methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HFD5486800.1"
                     /translation="MIKAILKEGERIDQLFSSDVGIIQNKDVFSYSIDSVLLSRFPKM
                     PSKGLIVDLCSGNGAVGLFASTRTKAAIVEVELQKRLADMGQRSIQLNQLEDQVTMIC
                     DDLKNLLNHVPRSGVDLMLCNPPYFKSHESSKKNVSEHYLLARHEVTTNLEEICQVAR
                     HALKSNGRLAMVHRPDRFLEIIDSLRANGLAPKRVQFVYPKLGKSANMLLIEAIKDGS
                     IEGMTILPPLVVHKENGEYTDHIFEIYFGTASKGKPNHDH"
     gene            7051..7329
                     /locus_tag="ACF4ZO_001268"
     CDS             7051..7329
                     /locus_tag="ACF4ZO_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HFD5486801.1"
                     /translation="MTTKKAYMYVLECADKTLYTGYTTDLKKRLATHNAGKGAKYTRY
                     RLPVSLLYYEVFDSKEAAMSAEALFKKRKTRSQKLAYIATHQKEKKNH"
     gene            complement(7353..9353)
                     /locus_tag="ACF4ZO_001269"
     CDS             complement(7353..9353)
                     /locus_tag="ACF4ZO_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015079 - potassium ion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="KUP/HAK/KT family potassium transporter"
                     /protein_id="HFD5486802.1"
                     /translation="MSDSHLTAFDKASKAGFIIALGIVYGDIGTSPLYTMQSLVENQG
                     GVNQVSESFILGSISLIIWTLTLITTIKYVLIALKADNHHEGGIFSLFTLVRKMSPWL
                     IIPAMIGGATLLSDGALTPAVTVTSAIEGLKAVPGLSHIYQNQTNVIITTLVILIVLF
                     GIQRFGTGFIGKIFGPVMFIWFSFLGVSGFFNTLGHLEIFKAINPYYALHLLFSPENH
                     RGIFILGSIFLATTGAEALYSDLGHVGRGNIYVSWPFVKVCIVLSYCGQAAWILANKH
                     SGIELNPFFASVPSQLRVYLVSLATLAAIIASQALISGSFTLVSEAMRLKIFPLFRVT
                     YPGANLGQLYIPVINWILFAVTSCTVLYFRTSAHMEAAYGLAITITMLMTTILLNYYL
                     IKEGVKPFLAHLVMTFFALVEFIFFWASAVKFMHGGYVVVILALAIVFVMFIWHAGTR
                     IVFKYVKSLNLNDYKEQIKQLRDDVCFDLYQTNVVYLSNRMQDYMIDRSILYSILDKR
                     PKRARVYWFVNVQVTDEPYTAKYKVDMMGTDYMVRVNLYLGFRMPQTVPRYLRTIVQD
                     LMESGRLPKQEQEYTITPGRDVGDFRFVLIEERVSNARQLSNFERFIMQTKASIKHVT
                     ASPMRWFGLQYSEVTLEVVPLILSDVLKLPIKELVPVEDSEA"
     gene            complement(9481..11100)
                     /locus_tag="ACF4ZO_001270"
     CDS             complement(9481..11100)
                     /locus_tag="ACF4ZO_001270"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HFD5486803.1"
                     /translation="MKFIEFNLSQDIQSAVVTAGFEKASPIQEMTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLNKIRTNENIIQALVIAPTRELAVQSQEELFRFGREKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALILDHVETLILDEADEMLNMGF
                     LEDIEAIISRVPADRQTLLFSATMPAPIKQIGVKFMKDPEHVQIKNKELTNVNVDQYY
                     VRVKEQEKFDTMTRLMDVNQPELSIVFGRTKRRVDEITRGLKLRGFRAEGIHGDLDQN
                     KRLRVIRDFKNDQIDILVATDVAARGLDISGVTHVYNYDITQDPESYVHRIGRTGRAG
                     KSGESITFVSPNEMGYLSMIENLTKKQMKPLRPATAEEAFQAKKKVALKKIERDFADE
                     TIRSNFDKFKGDAVQLAAEFTPEELALYILSLTVQDPDSLPEVEIAREKPLPFKYVGG
                     GHGNKNGKGGRGRDNRNRGDRRGGYRGDRNRDERDGDRRRQKRGKRDGHDGSGNRDFK
                     RKSKRNSKDFFNKEKKSSAKNTGFVIRHKGE"
     gene            complement(11407..12951)
                     /locus_tag="ACF4ZO_001271"
     CDS             complement(11407..12951)
                     /locus_tag="ACF4ZO_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HFD5486804.1"
                     /translation="MSLTEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKSGTFAKSDWMDIEKQRGISVTSSVMQFDYAGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRNIPVFTFINKLDRDGREPLELLEELEEVLG
                     IASYPMNWPIGMGRAFEGLYDLHNKRLELYKGDERFASIEDGDQLFANNPFYEQVKED
                     IELLQEAGNDFSEQAILDGDLTPVFFGSALTNFGVQTFLDTFLEFAPEPHGHKTTEGN
                     VIDPLAKDFSGFVFKIQANMDPKHRDRIAFVRIVSGEFERGMGVNLTRTGKGAKLSNV
                     TQFMAESRENVTNAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     PKNVMKQKSFHKGIEQLVQEGAIQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMTPMGKKTVRWISEDDLDQRMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     TLEEKM"
     gene            complement(13199..13894)
                     /locus_tag="ACF4ZO_001272"
     CDS             complement(13199..13894)
                     /locus_tag="ACF4ZO_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HFD5486805.1"
                     /translation="MDFFAIDPIGLPHTSLIFYLSSLLIALLLVFLTFQAYRLKSYRY
                     FFLFLQLSQVIGLYTWYVLRGFPLDEALPLYHCRIAMLAIFFLPDRNKFKQLFMVLGI
                     GGTFLALLSPDLYPFRLWHVANVSFYLGHYALLVNGLIYLLRFYDASQLRLLSVVRYL
                     ATVNFLLLLVSLATKGNYGFVMDIPVIHTRHLLLNFVIVTSGLTFMVKITEYFYLKFG
                     EAQQLAFAFSKEK"
     gene            complement(13974..15365)
                     /gene="murF"
                     /locus_tag="ACF4ZO_001273"
     CDS             complement(13974..15365)
                     /gene="murF"
                     /locus_tag="ACF4ZO_001273"
                     /EC_number="6.3.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047480 -
                     UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HFD5486806.1"
                     /translation="MKLTLHEVAKIVDAQNNVSDLDDVPLHHIEFDSRKITKGDLFLP
                     LKGQRDGHEFIDLAFQNGAVATFSEKELSGKPHLLVEDCLKAFQKLAHYYIDKMRVDV
                     IAVTGSNGKTSTKDMIGAVLSTTYKTYKTQGNYNNEIGLPYTVLHMPDDTEKIVLEMG
                     QDHMGDIRLLSEIARPRIAVLTLVGEAHLEYFGSRNKIAQGKMQIVDGMNSDGILIAP
                     GDPIIDPYLPENQMVIRFGNQQEIDVTGIQEDKDSLTFTTNVLATPVSLPLPGKYNAT
                     NAMVAAYVGKLLAVTDEDIIAALQTVTLTGNRTEWKKAANGADILSDVYNANPTAMRL
                     ILETFANIAKNPGGKKIAVLADMKELGKDSVILHSQLIDSLTSGNIDQLVFYGDHIKE
                     LARLASQVYPAEQVHYFLKTEQEDQFEAMAQYVQNILNPFDQILLKGSHSMSLEKLVD
                     RLVTDKNCDSYQP"
     gene            complement(15564..16610)
                     /locus_tag="ACF4ZO_001274"
     CDS             complement(15564..16610)
                     /locus_tag="ACF4ZO_001274"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HFD5486807.1"
                     /translation="MSKQTLVLLYGGRSAEREVSVLSAESVMRAVNYDKFLVKTYFIT
                     QMGQFIRTQQFSEKPSESERLMTNETIELTQKIKPSDIYEEGAVVFPVLHGPMGEDGS
                     IQGFLEVLRMPYIGTNVMSSSIAMDKITTKRVLESIGIPQVAYTVYIDGQDLEACLVE
                     TLARLTFPIFVKPANMGSSVGISKAQTKVELRKAIQLALTYDSRVLIEQGVVAREIEV
                     GLLGNDKVKSTLPGEVIKDVDFYDYQAKYVDNKITMAIPADVDQSIVTEMRSYAEVAF
                     KALGGCGLSRCDFFLTQDGQVYLNELNTMPGFTQWSMYPLLWENMGLAYPDLIEELVT
                     LAQEIFDQRESHLI"
     gene            complement(16711..17307)
                     /gene="recR"
                     /locus_tag="ACF4ZO_001275"
     CDS             complement(16711..17307)
                     /gene="recR"
                     /locus_tag="ACF4ZO_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination mediator RecR"
                     /protein_id="HFD5486808.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSNEDVNDFA
                     KNLLAAKRELTYCSICGNLTDDDPCHICTDTSRDQTTILVVEDAKDVSAMEKIQEYHG
                     YYHVLHGLISPMNGVGPDDINLKSLITRLMDGKVSEVIVATNATADGEATSMYISRVL
                     KPAGIKVTRLARGLAVGSDIEYADEVTLLRAIENRTEL"
     gene            complement(18096..18875)
                     /locus_tag="ACF4ZO_001276"
     CDS             complement(18096..18875)
                     /locus_tag="ACF4ZO_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015499 - formate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015724 - formate transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HFD5486809.1"
                     /translation="MKTPEQILEATIHIGEHKVTKTFLAKSILGFIGGAMISLGYLLY
                     VRIAASGLETFGAFSSIVGACAFPIGLIIILMAGGELITGNMMAVSAALLAKKIKFSE
                     LAKNWLIITLFNVIGAVFVAFVFGHFLGLTSAGIFKEEVIEVAHAKIAASPLQALVSG
                     IGCNWFVGLALWLCYGANDAAGKFLGTWFPVMTFVALGFQHSVANAFVIPAAIFEGGA
                     TWLDFVTNFIFVYSSNIIGGAIFVSFLYFKVYYHPQKSKTQ"
     gene            complement(18999..19541)
                     /locus_tag="ACF4ZO_001277"
     CDS             complement(18999..19541)
                     /locus_tag="ACF4ZO_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486810.1"
                     /translation="MIKKPTQLIAYTSILVAFAILIPIIMPLKLIIGPASFTLASHVP
                     LFLAIFMSIPVAILVALGTTLGFLLAGLPLIIVLRALSHLLFAILAAWWLSRKPQLMT
                     SAVKCFSFAFFINVIHGLAEFLVVYILTATTATSMSYFWSMLGLIGLGSLIHGILDFY
                     LALVLWRFLAKNLKLPTINA"
     gene            complement(19702..20223)
                     /locus_tag="ACF4ZO_001278"
     CDS             complement(19702..20223)
                     /locus_tag="ACF4ZO_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HFD5486811.1"
                     /translation="MKAEDRRQKIIECLNSEQKAVSATRLGKLLGVSRQIIVGDIALL
                     RAQQIDIISTPKGYIMSTALYSHQFCARIVCQHNVEETKKELEIILAHQGIITTVEVE
                     HPIYGMITAPLNIKTHSDVTNFMSKLSQSKAELLSSLTEGLHSHLISCPSQEAFLAIK
                     HDLELAGILYKGI"
     gene            complement(20330..21025)
                     /locus_tag="ACF4ZO_001279"
     CDS             complement(20330..21025)
                     /locus_tag="ACF4ZO_001279"
                     /EC_number="5.4.2.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HFD5486812.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIEFDLAFTSVLTRAIKTTNLALENAGQLWVPTEKSWRLNERHYGALTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPAMAKDDEYSAHKDRRYADLDPALIPDAENLKVTLERAM
                     PYWEEKIAPALLDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFELDE
                     KLNIVKEYYLGGE"
     gene            21264..22199
                     /locus_tag="ACF4ZO_001280"
     CDS             21264..22199
                     /locus_tag="ACF4ZO_001280"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004228450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HFD5486813.1"
                     /translation="MVSTATQIGHFSFDNCLMNAAGVYCMTKEELMEVEKSQAASFVT
                     KTGTLEVRPGNPEPRYADTRLGSINSMGLPNNGFRYYLDFVSDLAKTGQHKPHFLSVV
                     GLSPTETETILKAIMASDYEGLVELNLSCPNVPGKPQIAYDFETTDQLLENIFTYYTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLSFVNCVNSIGNGLVIKDEQVLIKPKNGFGGI
                     GGDYIKPTALANVHAFYKRLKPSIHIIGTGGVKTGRDAFEHILCGASMVQIGTALHQE
                     GPAIFERVTKELKTIMVEKGYQSLDDFRGNLRYKD"
     gene            complement(22499..24361)
                     /locus_tag="ACF4ZO_001281"
     CDS             complement(22499..24361)
                     /locus_tag="ACF4ZO_001281"
                     /EC_number="7.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015662 - P-type ion transporter activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0019829 - ATPase-coupled monoatomic cation
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFD5486814.1"
                     /translation="MTIRQWMADHLHLMETLACLVLIIIGLAFLHSFPQVASAIFITA
                     FLIGGYTSAKTGILDLVKNKHLSVDILMILAAIGAGIIGYWLEGALLIFIFSLSNTLE
                     EMAMEKSKDAISALMSLTPDTARQYQEDGHILEVETRSLSVGDRLQVRKGEAVPIDGQ
                     LLSPFGQFDESMVTGEPITVDKAEGQDLIGGTINQGQTIDMLVTIENDDTLFAKIINL
                     VESAQEKKSKTATFIESLEDGYVKFVLVLIPAFILFSHFVLSWTWLAAFYRGMILLTV
                     ASPCALIASSTPASLAAISRAARKGLIIKGGDIVDNMGDIKAVVMDKTGTLTQGKPSV
                     VNAHYLEDELLVNRLVKGAETASTHPISKALLEYTEKLEPLTFDHLEEISGKGFQGFY
                     QGQEWRIGKKTFILEKVQDLSAFEETIQVEENQGKTLIFVSRDHQLIAYYALLDDIKI
                     ESKRAIKSLHAMGIKTVMLTGDQERTANYVAQKLGIDEVVANCMPQDKVAKLAELKTK
                     YGFVAMVGDGINDAPALAQADVSYAIGSGTDIAMESADSVIMDDLTRIPFSIQLSRKM
                     KTIIKQNIVFALSVITLLILANVFQVVNLPLGVVGHEGSTILVILNGLRLLSFK"
BASE COUNT         7567 a         4993 c         4088 g         7897 t
ORIGIN      
        1 tttttgttct aaagcagcta acatttgtct ttttttatta atttcagctt ttagattatt
       61 tatttccaaa tctagaccat ttattttttc atctattttt tttatttttt cttttaactc
      121 ttttaccttt tcatcttcag ccttttgttc ttcttctaat ttcaaaagtt tttctttaag
      181 agtttttatc tcatttgctg tcttttcact taaagccttg ctagcatttt tttcttgttc
      241 taattcttct atttctttct tgtttgcgtc aatgttctct tgaatttttg ctttttcttc
      301 ttcaagatct ttaattgctt ggtctttgtt gtctaaaccc tttaatttat tttgtttttc
      361 tttaatggta ttttgaatat ttttaagttt ttcttcttct tcagataaat ctttctttgc
      421 ttttttcaca agttcttttt gggtatctct tgccttttta gcttcttctg cttgcttctc
      481 gaattgtggc ttgcttttat ttgtatcctc aatttctcct tcaagacctt gaatttcttt
      541 ttcaagttta gctttctcag ccaataatct ttcaagtttt tccaattttt cttgattttc
      601 ttttattaat ttttcaaggt tagctttttc tctttcttga gttaaaagaa caatttctcc
      661 acctttaacc ttattttctt ctgtttttat ttcttctttc aatttctcaa ttcttgtttc
      721 aacatcttgt ggaatattgt tttggatttt cttttctatc tcttgtgatt cttgttgttt
      781 aggtcctatt tttgtcttta tttcatctac tttagatttt ttttcttgaa tttgtttatc
      841 aagctctcta tttttactct ctaatcctgc tttttcttgt tgcgcttttt cttttttgcc
      901 tgtaagctca gtgattttag tccctatccc tgctttttct tgttctttag attgaatatc
      961 tttttttata gtttcaatta tttgatcaaa accagggtct tcgtctggtt taacagtgcc
     1021 ttcttctttt gcctgttcat atctttgttt agcatcttgt gcttctttta gagcaaaatt
     1081 aaaatcttgt atttttcttt tagcctcttc aagctttcct tgttctccgc caatctcacc
     1141 gtcaagtttt aatacttcct tgcctttttc ggtaatcatt tgagagtttg tttgcttttg
     1201 agcttctaat tctttttgag tgttttcaag acctttcatt tcatcttcca aagctttaat
     1261 ttctttttct atttcttcta atttttgatc taatgcagga ccatgtggtg gatattgctt
     1321 gtttaatttt tctaattcgg ttcttttttc ttctaaattt ttcttagctt tatcataagc
     1381 tgtttgaaga gtttttgtgc tagtcttgtt tgtttctaat ttttctttaa gctttttgtc
     1441 tttatcgata agatcatgtt tgcttgcatt tatgtctttt atagcttttt ctgtagtttg
     1501 ttttttctct cttgctttag ctatttcttt ttcaaacttt tctaaatctt tcttatctct
     1561 ttcaacaaga gcattttctt ttacataatc agcttctttt ttctctaaat ctttttttgc
     1621 agattcaaga tttgccttta actctgttac tttttctgaa ctctcttttt ctttttgttt
     1681 ctctgctgtt aatgcatctt caatagattg tttacttgcc gaatcaagtt tttttagttc
     1741 atctatcatt tcatcttttt ccttgagatc ttttgctaaa gtttcttttt ctccattagc
     1801 tttttgaagt ttttctttaa aaaactcaag cattttttta ttttcttctt gtttactttc
     1861 aagttcttta atcttattat ttaaagtttt tatttcttta tttaatcttt cattttcctt
     1921 ggatagttta tcagaaattt cagatttttc tttaagcaat ctttctcttt tatttatttt
     1981 ttctgataat tctttttcca tttgtgctat ttctttttta ataatctcaa tcttagcctt
     2041 gtcgtcaatt tttgtagaat ttacctcaag attttcttta gcctttgcca aatctacttt
     2101 tgaaaaaagt atgcttgatg acagggccgc aaccattgcg tattttgcta ttttgctttt
     2161 tgttgtttgt tgtttgttgt ttgttgtttg ttgtttcata ttttatacct cgtcttttat
     2221 attgtattag ttgtgtttca tatatttctt aattttagca aaataaaact aaactgtcaa
     2281 caaaatccaa aacaaaatat attttgaaaa gaaatttttt ctccactata aacgtttgaa
     2341 attcaaagtt tttattaaaa aaatgataat tatgaggatt ttttaaaaac attcctagaa
     2401 aaaattatta atttccaaat atatatataa aattatttta tctaaaattt gttttttata
     2461 aaaactaaaa gtacaaaaat aattcataat tctggtttta ttaattattt ttgaattttt
     2521 tataaatttt acccgtggtg ctagttaatg tcagaataca ataaaaagcc caaaaggact
     2581 atactgtaag tgttcaaaca aacaggaggt tagtcccaat gagccactta cagtataccg
     2641 ctaaatccca tcacttacaa tggaatgtca cacaattatc tacgatttgc catcagctat
     2701 atcgtgatta ttgtccagaa ggcttaaaac accgtcgtaa cattagcttg tccaaggtct
     2761 cagatgagtc tctactagtc ttgcttgtct tgcaagctga attaggtatt aagtcacaac
     2821 ggcattttta tcgtatctgt caactctttc cttgcggtca tctccttgaa agaagtcgtt
     2881 ttaatcgacg agcaagacaa ttaatttggt tagtccaagt cattagacaa gccatgaatg
     2941 ctcgaatgtc tcctgataca atagtcatca tcgacagttt tcctctacca ctttgtcaac
     3001 ctgtccgtaa tcatagagcc cgtattttta aagggcgccc acctacatct attaagagat
     3061 ttttccctgt ccactccctc accaaaatac tatctccctg gccaatgtcg ataaaggtca
     3121 cttcattagt caaaggatat ttgacagaca aaagcgtcaa cgctataacc aaaccgcaag
     3181 tgataactcg ttgtcgcacc tgccgataat cataaaaaat agcgaagcta atcaccaaga
     3241 taagcaagtg ccagctggtc gggcttccaa aaacaaggga actattgaaa gtatttccga
     3301 gaaattgaat gactttttct aagaaaagaa agagataatt acatcctgag agagttatca
     3361 aaggagacaa acagaaaacc agacaaagaa ggggcaaaat aaaaagggca aagaaataag
     3421 acaagagagc tgttaagacc attgacattg ggttaaaact ggaaaaataa aagagcaaaa
     3481 atgataatat tcctagggaa atggtcaaga cttgtaccaa ctgtctttta gctcctgata
     3541 attcttcaac agtaaccact gttaacaaaa aagcatagct aaacgttaat acgccaccaa
     3601 cagtcattaa gaaatgggca tcccataaaa agacaagtaa aaaagtacaa gcgagattgt
     3661 ctaatccttt tattcctaaa tgacgcaact gcgactgcac gaggcttcga ataacagaaa
     3721 tactataacc tgtcaacgcg gcataaaagc aagcaaaagg aagctctatc cattttatcc
     3781 attccaaagg aactgcgagt aatagcaaca cccttttaaa acaagtaaga aagaagccaa
     3841 cctgcatccc tgataaagca aagagatgaa tgatacccaa ctgactataa taatctgtca
     3901 tctcaccaaa cgacttatct aaataaccaa aaaggaggcc cgtcaggtag tgagacatag
     3961 gacttggaaa atgctgttgg caatgaacaa tggctcgccg tcttaaagag gacaaatagt
     4021 cacatattga cttgggtgaa atcacttcaa gctgttctat ttgctctacc ttccctatcc
     4081 tgtaaattcc ttgataagcc aaaaaagtct gataattaaa gcctttaaaa tttcgaactt
     4141 cctcagcttt ttccaatgtc acttttgcgt gcatcactaa ccaacggtgc tctttcttga
     4201 acaattgggc ttctgcttgg cttttcaaac ggtaaaataa ctgataagaa tgtttcccgt
     4261 gacgtccaag aacagctaat tgatcaccat taatccgaat actatcagga actaatgcta
     4321 cagaggttat ttgtactggc tgaatttcca gtttttgaac caactgctgt ttctgataca
     4381 gcaaaaacaa agcacagaaa ctaaggatgg caaagacacc gagaaattct tttttagaca
     4441 aacgcttgac aagtaagcaa atcaaactaa ggctaaggag aaacgttaac cagctagggc
     4501 tatggatttg ataaaagaga accaagatta aaaaagcaaa ttgaatcttt gacaggggca
     4561 ctagcttagt ccaagaaaat gtcatctttt aatttctcga gcgttttttc gccaatcccc
     4621 gaagcctgac ggagatcttc taacgcttta aaaccaccta acttatctct catatcaata
     4681 atatcctgag ctcttttagc accaatacct gggatatgtt gtagttcttc taagctggcc
     4741 ttattaatat gaacctttga ctgatccttg ctggcagttt cttttttacc agaaactaat
     4801 gatcttggta gcacagaaat ctcttctcct tgtttaggta cataaacaac ttgctcatca
     4861 gttagttttt ctgcaaaatt aatagcatgt ttatcagctt ctgaagttag gcctccagct
     4921 agttcaatga catctcgcac acgactgcta gcagttagct tataaactcc ctctttttgt
     4981 acggcgcctt ttaaatccac taaaatactg ctatcttctt gaatttcctt tttttcttca
     5041 ctaacctgct gtttcacagg cgatatctct ctcaaagcag gaacggctgc cttgctctgc
     5101 ttatttcccc agaacaaaaa actgaagctt agtattagaa aaagtcctaa taaaagacta
     5161 attaggtatg gcagaaaata ccgctctctc aaaaacgatt ttcctttaat taataattcg
     5221 tctaacattt ttttacctca tctttttatt cgtaaatgat atcccaaagt atagtagtat
     5281 tgtcattttt tgtgcttaaa agagttaagg gtgtcatcga atatcttttt tagaaatgaa
     5341 aaagtgatta agcattagcg gcttctttca atagaagact aatctcaatc acttcttatt
     5401 tcaggcacat gttagccctc atgttcttaa tggcgatgtt tatctggatt ccaaacaaaa
     5461 ctagcgatat aggaaaataa catggttaat aataataccg ccaccaaaac caatcctaat
     5521 ggtaaacggt agagataagt taaagggttc cttgctttgc ctggttggaa aggtgccaac
     5581 tcgtcatcca tccgatcaaa ctctgcctga atacggtttg ccacctcagc aatcccttca
     5641 tcattcatgc gtttaatatc tgagacgtca atgggattcc caaaagtcat gtcaacccgt
     5701 tctcccgcta gtaatccctt gaccgacata ggcccctgat aggctgctgg cataatcttg
     5761 accttagcca ttttagcaat cacagcaacc cctcctttga cctcttgcga atgcctactt
     5821 ccacttggaa acataagaag agaacgattg ctctttttga gcatattaac agggtaacga
     5881 atagcatctg gactcggttt gtcacgatca ataggaaaag caccacacat tttaatccac
     5941 caagcaaaga gacgatttgc aaacaactct tttttagcca taaaaataaa ctgcttaggg
     6001 cgtgctgcaa atgccatgta aactggatcc caaaaggttc gatggggtgc taccagaata
     6061 taattctcag aagcatctaa catcttttct tcatgatggt agtgggcatt gccattgaca
     6121 acccataata aaaagactac taaaccgcgt aagtaagcgt aaaacacagg cttctccttt
     6181 aatagaataa tcttacttat tgtatcatga aagttgactt ttcgaaagtc aaaatcactc
     6241 ttcaaacatt cacctcaagc ctattttatg ttaaaataac aggtatgata aaagcaatct
     6301 taaaagaagg cgaacgtatt gatcaactct tttcaagtga tgttggcatt attcaaaaca
     6361 aggatgtctt tagttactct attgatagcg tcctcttatc ccgcttcccc aagatgcctt
     6421 ccaaagggtt aattgtggat ttgtgctcag gaaatggggc ggttggctta tttgctagca
     6481 ctagaaccaa ggcagccatc gttgaagtag aattacaaaa acggcttgct gatatgggac
     6541 aacgctctat ccagctcaat caactggaag accaagtaac catgatttgt gatgatttaa
     6601 aaaatctcct aaaccatgtg ccacgttcag gagttgattt gatgctctgc aatccccctt
     6661 actttaaaag tcacgaaagt tctaagaaga acgtctctga acattattta ctggctcgtc
     6721 atgaagtgac cactaattta gaagagattt gtcaggtagc ccgtcatgcc cttaaatcaa
     6781 atggtcgtct ggcaatggtt catcgaccag atcgattctt ggaaattata gatagcctta
     6841 gagctaatgg tcttgcccct aaaagggtac aatttgtcta tcctaaatta ggtaaatcag
     6901 ctaatatgtt acttattgaa gcaatcaaag acggttctat tgaagggatg actattttac
     6961 ctcctttagt tgtccacaag gaaaacggag aatacactga tcatattttt gagatttatt
     7021 ttggtactgc ttccaaagga aaacctaatc atgaccacta aaaaagctta tatgtatgtg
     7081 ttagaatgtg cagataaaac cctctacact ggttatacaa ctgatttgaa aaaacgctta
     7141 gctacacata acgcaggaaa gggggctaaa tatactcgct accggttacc tgtttcttta
     7201 ctttattacg aagtgtttga tagcaaagag gctgcgatga gcgctgaagc actctttaaa
     7261 aaacgaaaaa caagaagcca gaaattggcc tatattgcta ctcatcaaaa agaaaagaaa
     7321 aatcattgag acttatcatc tcaatgattt ttttatgctt cactgtcttc cacaggcacc
     7381 aattctttga ttggtaactt caagacatct gatagaatca agggaaccac ttcaagggtt
     7441 acttctgaat attgaagccc aaaccaacgc attggactag cggtaacatg tttaatgctt
     7501 gccttagtct gcataataaa gcgttcaaag ttactcaatt gacgtgcatt ggagacccgt
     7561 tcttctatta aaacaaagcg aaaatcacca acatcacgac caggtgtgat ggtatattcc
     7621 tgttcttgtt tgggtaaacg gccactttcc atcaaatcct gaacaatcgt gcgcaaatag
     7681 cgtggcacag tctgtggcat tctaaaacca agataaaggt tgactcgaac catataatcc
     7741 gttcccatca tatctacctt gtacttagct gtataaggtt catcagttac ctggacattt
     7801 acaaaccaat aaactcgagc gcgttttggc cgcttgtcta aaatggagta taaaatagac
     7861 cggtcaatca tgtaatcctg catacgattg gataagtaga caacatttgt ttggtagagg
     7921 tcaaaacaaa cgtcgtcacg gagttgttta atctgctcct tataatcatt caaattaaga
     7981 gacttcacat acttgaaaac aatgcgtgtg cccgcatgcc agataaacat gacaaagaca
     8041 attgctagcg ctaaaataac cactacatag ccaccgtgca tgaatttgac agcggaggcc
     8101 cagaagaaaa tgaattctac aagggcaaag aaagtcatca ctaaatgagc taggaaaggt
     8161 tttacacctt ctttaatcaa atagtaattc aataatatag tggtcattaa catggtaatg
     8221 gtaatggcca ggccataggc tgcttccata tgagcagagg ttctaaaata caaaaccgta
     8281 caggacgtga ctgcaaagag aatccagtta atcaccggaa tatacaattg ccccaaatta
     8341 gcaccaggat aagtcactcg aaatagaggg aatattttta agcgcatggc ttctgaaacc
     8401 aaggtaaaag aacctgaaat taaggcctgt gaggcaataa tagctgctaa ggttgccaaa
     8461 ctaacaaggt aaacccttaa ttgtgatggc acactagcaa agaaagggtt tagttcaata
     8521 cctgagtgtt tattcgctaa aatccacgca gcctggccac agtaagacaa cacaatacac
     8581 accttaacaa aaggccagct cacataaata tttcctcgac caacatgtcc caaatccgaa
     8641 taaagggctt cagctcctgt tgtcgcaaga aaaatggacc ccaagataaa aatcccacga
     8701 tggttttcag gactaaacag caaatgcaga gcatagtaag gattgatagc cttgaaaatt
     8761 tccagatgcc ccaacgtatt aaaaaaacca ctaacaccta gaaaactaaa ccagataaac
     8821 ataactggtc caaaaatttt accaataaaa cctgttccaa acctctgaat accaaacaag
     8881 actattaaaa tcactagagt tgtgataatg acattggttt gattttggta gatgtgactc
     8941 agaccaggaa cggctttcaa gccctcaata gctgaagtaa ctgttaccgc aggtgtaaga
     9001 gccccatcag acaaaagtgt tgcacctcca atcatcgccg gaataatgag ccacggtgac
     9061 attttacgta ccaaggtgaa taaagaaaaa atcccacctt catggtggtt atcagctttt
     9121 agagctatca aaacgtactt gattgttgtg atcaaggtca gtgtccaaat aattaaagag
     9181 attgatccta aaataaagga ttcagaaacc tgattaaccc ctccttgatt ttcaactaga
     9241 gactgcatcg tataaagggg gctcgttcca atatctccat aaacaatacc taaagcaata
     9301 ataaaacctg cttttgaagc tttgtcaaag gcagtaagat ggctatcaga catcttatac
     9361 tcctcctaat tttttaaaaa ttatcacaaa aataactgaa accattataa cagattccat
     9421 tataaaagca actttttcag aaaattaaaa agagctgact ctcatcaact ctctttaagc
     9481 ttattcacct ttgtgacgaa tcacaaaacc agtattttta gcacttgatt ttttctcttt
     9541 attgaaaaag tctttactat tacgttttga tttacgtttg aaatcgcggt tgccactgcc
     9601 atcgtgacca tcacgcttac cacgtttttg acgacgacgg tcaccatcac gctcatctct
     9661 gttacggtca ccacgatagc cgccacggcg atcaccacgg ttacggttgt cacgtccacg
     9721 accacctttg ccatttttat tgccgtgacc accacccaca tatttgaatg gtaatggttt
     9781 ttcacgtgca atttcaactt ccggtaagct atctggatct tgaactgtta agctcaaaat
     9841 atataaagct aattcttcag gagtgaattc ggcagccaat tggacagcat cgcctttgaa
     9901 tttatcaaag tttgaacgaa tagtctcatc cgcaaagtcg cgttcaattt tcttgagggc
     9961 tacttttttc ttggcttgaa aggcctcttc agcagttgct gggcgaagag gtttcatctg
    10021 ttttttcgtt aagttctcaa tcattgagag gtagcccatc tcatttggtg agacaaaagt
    10081 gatagactca ccagatttac cggcacgacc tgtacgacca atacggtgaa cataactttc
    10141 tggatcttgg gtaatatcgt agttataaac gtgggtaact cctgaaatat caaggccacg
    10201 cgctgctaca tcagtggcaa caagaatatc aatttggtcg tttttgaaat cacggataac
    10261 acgtaagcgt ttattttggt caagatcacc atggattcct tcggcacgga aaccacgaag
    10321 tttcaagcca cgtgtaattt catcaactcg gcgcttagtc cgcccaaaaa cgatggataa
    10381 ttctggctgg ttaacatcca tcagacgggt catagtgtca aatttttctt gttctttcac
    10441 acgaacatag tattgatcaa cattgacgtt tgttaattct ttgttcttaa tttgaacatg
    10501 ttcagggtct ttcatgaatt taaccccgat ttgtttaata ggtgccggca tcgttgcgga
    10561 gaagagcaag gtctgacggt ctgctgggac acgactgata atagcttcaa tgtcttccaa
    10621 gaagcccatg ttaagcattt catctgcttc atcaaggatt aaggtttcca catgatctaa
    10681 aataagagcc ttgcgcttaa tcaaatctaa caagcggcct ggtgttccca cgacaatgtg
    10741 ggcacctgat ttaagggctt tgatttgttt ttcaatactt gatccaccgt aaacagagcg
    10801 aaccttaacc cctttttcac gtccaaaacg gaacaattct tcctgacttt gtacagccaa
    10861 ttcacgcgtt ggtgcaatga ccaatgcttg gatgatattt tcgttagtac gaatcttatt
    10921 caaggttggt agaccaaacg ctgctgtttt accagttcct gtttgtgctt gaccaataac
    10981 atccttccct tctagtgcga gaggaatcgt catttcctgg ataggagatg ctttctcaaa
    11041 accagcggta acaacagctg attggatgtc ttgtgataag ttaaattcta taaatttcaa
    11101 ttgtttctct tttctaaaaa ggcagtgcga agctgcctta taaacctttt aattttcgtc
    11161 gtttgattaa caacctaact agtgtaacac aattagaatc aaaaagatag gaaataaggc
    11221 taatataagc aataacacgc tttcacgatt atccgaaaaa tcataaatat gcttacagtt
    11281 gtgaagatat cgttttttga tagaatctta aatctgcaaa agagataact agccactcat
    11341 ttcttttaaa aagttgctca gtaaattgat ctccaaaacg ttagactgtt gaaaatcatg
    11401 tttcgattac attttctctt ctaaagtgac atctgggtat ttgtctgcaa accagcgaag
    11461 ggcaaaatca ttttcaaata ggaaaactgg ttggtcaaaa cgatccttag ctaaaatgtt
    11521 tcggcttgag gacatgcgtt gatccaaatc atcttctgaa atccagcgaa cagtcttttt
    11581 acccattggt gtcatcacaa cttcagcgtt gtattcacct tccatacgat gtttaaagac
    11641 ttcaaactgc agttgaccca cagcacccaa catgtattcg cctgtctgat aattcttata
    11701 aagctgaatt gctccttctt gtactaattg ctcaatacct ttgtggaagg atttctgctt
    11761 cataacattt ttcggagaaa ccttcatgaa gatttctggg gtaaaagttg gtaagggttc
    11821 aaattcaaat ttatttttcc caactgttaa ggtatcccca acttgataag ttcctgtatc
    11881 ataaaccccg ataatatccc cagcaacagc attcgtcaca ttttcccgtg attctgccat
    11941 aaattgagta acattggaga gcttagcgcc tttgccagtg cgtgtcaaat taactcccat
    12001 accgcgctca aattcaccag aaacaatacg cacaaaagca atacggtcac ggtgtttagg
    12061 gtccatgtta gcttgaattt taaagacaaa acctgaaaaa tctttagcta aggggtcaat
    12121 aacattacct tctgtagtct tgtgaccatg aggttctggg gcaaactcca agaaagtatc
    12181 aagaaaagtc tgaactccaa agttcgtaag ggcagagcca aaaaaaactg gagttaggtc
    12241 accatcaaga atagcttgtt ctgaaaagtc attacctgct tcttgaagaa gttcaatatc
    12301 ttctttgact tgttcataaa agggattatt ggcaaacagc tgatcaccgt cttcaatact
    12361 tgcaaaacgc tcgtctccct tatagagttc taaacgttta ttatgtaaat catataagcc
    12421 ctcaaaggcg cgtcccatac caatcggcca gttcatcgga taagaagcaa tccctaaaac
    12481 ttcttctaat tcttccaaga gttctaaagg ctcacgccca tcacggtcta acttgttaat
    12541 aaaggtgaag acaggaatat tacgatgttt gacaacttca aaaagttttt tcgtttgcgc
    12601 ctcaatacct ttagccgaat ctacaaccat gacagccgca tccacagcca ttaaggtccg
    12661 gtatgtatct tccgagaaat cctcatgtcc aggtgtatcc aaaatattaa cacgtttacc
    12721 cgcgtaatca aattgcataa cagatgaagt aacagagata ccacgttgct tttcaatatc
    12781 catccagtcg gactttgcaa acgtacctga ttttttccct tttactgtcc ctgcttctct
    12841 aatttcacca ccaaaatata atagttgctc agtaatagtc gtcttaccag catccgggtg
    12901 agagatgatg gcaaaagtac ggcgtttttt aatttcttct gtaagtgaca ttcttttttc
    12961 cttgtatagt aaaatggcag agcttttctc tgagttattt tcgttaggta ttacttgttt
    13021 atcaaaagag ttgggctaca ttgggtttct ccatatacga ttagcctcta aagttcttca
    13081 aaactggtat tataacttat cttgggctat caatgagtgt cttttttaaa aaaatcgagc
    13141 ctggaaatca tcccagactc ttcttattat agctgatttt aagtgctttt tcaacgacct
    13201 acttttcttt agagaaagca aatgccagct gttgagcttc accaaattta aggtaaaaat
    13261 attcggttat tttaaccata aaagtcaagc cacttgtaac gatcacaaaa ttaagtagca
    13321 aatgacgcgt atgaatcact ggaatatcca tcacaaaacc ataatttcct ttcgtggcta
    13381 aactgaccaa cagaagaaga aagttaacag ttgctaaata gcgtactact gatagcagtc
    13441 ttaactgact ggcatcgtaa aaacgcaaga ggtaaatcaa accattcact aacaaagcat
    13501 aatgaccaag ataaaatgag acatttgcta catgccataa tctaaacgga taaagatctg
    13561 gcgataaaag tgcaaggaat gttccaccta tccccaaaac cataaataat tgcttaaact
    13621 tgttacgatc aggtagaaaa aagatagcta acatagcgat gcgacaatga tacaacggca
    13681 aagcttcatc taaaggaaac ccccttaaca cgtaccatgt gtacaagcca atcacctgag
    13741 ataactgtaa aaacaagaaa aaataacgat aagattttaa cctatatgct tgaaaagtca
    13801 aaaaaacaag caaaagcgct atcaagagtg acgacaagta aaagataagt gaggtatgag
    13861 gcagtccgat ggggtcaatt gcaaaaaaat ccataatcgt ccctttctat attttttcat
    13921 tataccttaa tcttcatgag agaacaagcc tttctctgaa agttttataa aaatcaaggc
    13981 tgatagctgt cacaattctt gtcagtcact aatcgatcca ctaacttttc aagcgacatc
    14041 gagtggctgc cttttaaaag aatttgatca aagggattaa gaatgttttg aacatattgt
    14101 gccatggctt caaactggtc ttcttgttca gtttttaaaa aataatgtac ttgctcagca
    14161 ggataaacct gacttgccaa ccgtgctaat tctttaatat gatccccata aaaaacaagc
    14221 tgatcaatat tacctgatgt taagctgtca attaactgag aatgaagtat cactgaatcc
    14281 tttccaagtt ctttcatatc tgctagcact gcaatctttt ttcctccggg gttctttgct
    14341 atgttagcaa atgtttctaa aatcagacgc atggctgttg ggttggcatt gtagacatct
    14401 gataaaatat cagcaccatt ggctgctttt ttccactccg tacgattacc tgtcaacgtc
    14461 acagtctgta aagcagctat aatatcctcg tctgttactg ccaatagttt tcctacatag
    14521 gctgctacca tagcattggt cgcgttgtat tttcctggta gaggtaggga cacaggtgtt
    14581 gctaacacat ttgttgtaaa cgttaagcta tctttgtctt cttgaatacc agtaacgtca
    14641 atttcctgct gatttccaaa acggataacc atctgatttt ctggaagata tgggtcaata
    14701 atcggatctc ccggagcaat taaaatccca tctgaattca tgccgtcaac aatctgcatt
    14761 ttgccttggg ctattttgtt tcggcttcca aaatattcta aatgagcttc gccgactaag
    14821 gttaaaactg caatacgagg ccttgcaatt tcagacagaa gacgaatatc tcccatgtga
    14881 tcttgtccca tttcaagaac aattttttcc gtatcgtcag gcatgtggag aacggtgtaa
    14941 ggcaaaccaa tctcattatt gtaatttcct tgcgttttgt aagttttgta agtggttgat
    15001 aggacagctc ctatcatatc tttggtggaa gttttaccat ttgagcctgt cacagcaata
    15061 acatccacgc gcatcttatc aatataataa tgggctagct tttgaaaagc ttttaggcag
    15121 tcttcaacaa gaaggtgagg tttccccgac aattcttttt ctgaaaaagt agcgacagct
    15181 ccattttgaa aggctaaatc aataaactca tgaccatccc tttgaccttt taagggtaaa
    15241 aagaggtctc cttttgtaat ctttcggcta tcaaattcaa tgtgatgcag aggaacgtcg
    15301 tctaagtcag acacattatt ttgggcgtca actattttag ccacttcgtg taaggttaat
    15361 ttcattttgt tttctttcta agaacactag tatttacgat gtcctatcta ttatagcaca
    15421 aaacattaga aaaatttcta aaatgtcaaa ctcccttaat ggctctacta ttcttcctaa
    15481 aagagcaaca aaaaaaggac gaacgtcaca tcttgacgat gtttgccgtt ccatccaagt
    15541 caatgtttat tcatctcata ggtttaaatc agatggctct cacgctgatc aaatatttct
    15601 tgtgccagtg tcaccagctc ttcaatcaaa tctggataag ccaatcccat attttcccat
    15661 aagagtggat acatagacca ttgggtaaag cctggcatgg tgtttaattc gttaaggtaa
    15721 acctgtccgt cttgggtcaa gaaaaagtca caacgggaca acccacaacc acctaaggct
    15781 ttaaaggcta cttcagcata agaacgcatt tctgtcacaa tactctgatc tacatctgct
    15841 ggaatggcca tcgtaatctt attatcaaca tattttgctt ggtagtcgta aaaatcaacg
    15901 tccttgatta cttctcctgg tagagttgat ttaaccttat catttccaag gagaccaact
    15961 tcaatttctc tggcaactac gccttgttca atcaaaacac gactgtcata ggtcagggct
    16021 aactgaatcg cttttcttaa ctctactttt gtttgggctt tggaaatccc cacagaagaa
    16081 cccatattag ctggttttac gaagatagga aaagtaagtc ttgctaaagt ttcaactaaa
    16141 caagcctcca aatcttgtcc gtcaatataa acagtatagg caacttgtgg aattccaatt
    16201 gattctaaga cacgtttagt agtaatttta tccatagcta tgctagaaga catgacatta
    16261 gtccctatat atggcattct aagcacttct aagaaacctt ggatagagcc atcttctccc
    16321 ataggtccat gtaatacagg aaatacaact gcaccttctt catagatatc acttggtttt
    16381 attttttgag ttagctctat cgtctcattt gtcatcaagc gttctgattc cgatggcttt
    16441 tctgaaaatt gctgagttct gataaattgg cccatctgag taataaaata agtttttact
    16501 aagaacttat catagttgac tgctcgcatc acactctctg ctgaaagcac tgagacttca
    16561 cgttctgctg agcggcctcc gtataataga actaacgttt gtttggacat agctaacctt
    16621 tcttatctga attgaatgtt tttttattat aacaaaaaga tgtagccttt tcaaaacctc
    16681 tctttgcgag taaaggcacc aacatgatca ttaaagttca gtacgattct caatagctct
    16741 caataatgtt acttcatcag catactcaat atctgaacct actgcgagac ctcttgccaa
    16801 acgagttacc ttaatcccgg ctggtttcaa gacacgtgaa atatacatgg acgttgcttc
    16861 cccatctgct gtggcattgg tagctacgat aacttcgctc accttaccat ccattagacg
    16921 ggtaattaaa cttttaaggt tgatgtcatc tggccccaca ccattcatag gcgaaatcaa
    16981 gccgtgaagc acatgataat agccatgata ctcttggatt ttttccatgg cagaaacatc
    17041 tttagcatct tctactacca gaatggtcgt ctgatcacgg ctcgtgtctg tgcaaatgtg
    17101 acaaggatcg tcatcggtaa ggtttccaca aatcgaacaa taggtcagtt ctcttttagc
    17161 tgctaataaa tttttagcaa aatcattgac atcttcattt gacattccaa tagtataaaa
    17221 ggctaatctc gtcgccgtct tgataccaat tcctggaagt ttagagtaac tgtcaattaa
    17281 ctttgcaatg ggtgttggat aaagcactaa gttctccttt attgttttcc atatatcgcc
    17341 acataaagcg ccctcacatc tttgccgata tattcgtaat atgtacagca accgcaatat
    17401 tatcttcgtt atttgtatta taagctacta catttaagtt gtaagttact aaggtctgat
    17461 ctgaattgtc tgtgatacaa gtctcagcag ttccaatttt agcgtgaatc gtgacagaac
    17521 cgtttggatt agccaagtaa aaactttttt actcgacttg ttaccttggc cttgggatat
    17581 ttggcttttg ttttttgatt catgttactt ttttagaaac cgcaaaccat ccttatgata
    17641 taagtttata ggaattgttt cattccatgc agaaatgatg tttactcaat tgaatatgct
    17701 atttttctca acaatagtgc ataaagcaaa ctcatggtta tctttaagct ttcatgctac
    17761 actttcttca ctaaaagtgt attaccaaaa gcattattaa gaaatctcta agcacaaacc
    17821 ataagatagt ttgtacgcct gatgaatctg ttgctgcatt actgtccact ttttacccta
    17881 tcaaggctat ttttgaaaga caactaatga tctgcattat tttgggaact actcccatag
    17941 caaattcttt ttacggattt tctgggaata ctcatttttt agggaataaa ctaaccatta
    18001 tttagctaaa ttttttaaac ttcgcttctt attttaccat aaattataaa aagaagactg
    18061 agaataggac gccctcagtc taaaaaaata ttttctcatt gagttttact cttttgcgga
    18121 tgatagtaaa ctttaaaata taaaaaacta acaaaaatgg ctccaccaat aatattacta
    18181 ctatagacaa aaataaaatt agtgacaaaa tccaaccatg ttgctcctcc ttcaaaaata
    18241 gcagcaggaa tgacaaaagc atttgctaca ctatgctgaa aaccaagggc tacaaaggtc
    18301 atgacaggaa accaagtacc aaggaattta ccagcagcat catttgcccc atagcatagc
    18361 cacaaggcca aaccaacaaa ccagttacaa ccaattcctg atactagtgc ctgcaaaggg
    18421 ctcgctgcta ttttagcatg ggccacctca atcacttctt ctttaaaaat accagctgat
    18481 gtcaaaccta gaaaatgacc aaacacaaaa gctacaaaaa cagctccaat cacattaaac
    18541 aaggtaatga taagccaatt cttggcaagc tcgctaaact taattttttt ggccaacaaa
    18601 gctgcagaaa cagccatcat gttccctgta attaattctc cacccgccat taaaataata
    18661 attagaccaa tcggaaaagc acaagctcct acgatactgg aaaaagcacc aaaagtttct
    18721 aaaccactgg cggcaattct cacgtagagt aaataaccaa ggctaatcat cgctccacca
    18781 ataaagccta agatagattt agccaaaaaa gttttggtaa ccttatgttc cccaatatga
    18841 atagttgctt ctaaaatctg ttctggtgtt ttcatgatat ctccttttgt tactatattc
    18901 acaaacacac attttagtat atcaatttcc ctaaaaaatg caagcccttt caacaagaaa
    18961 gggctcgtca ttatcatata actatctcta ttttagtctt aggcatttat ggtgggaagt
    19021 tttaagtttt ttgctaaaaa acgccataga actaaagcaa gatagaaatc caatatgcca
    19081 tgaataagcg aacctaagcc aatcaagcct agcatagacc aaaaataaga catagaagtt
    19141 gctgtggttg ctgttaaaat atagacaact aaaaattcag ccaagccatg aatgacatta
    19201 atgaaaaacg caaaactaaa acattttact gccgatgtca tcagttgtgg ttttctactt
    19261 aaccaccacg ctgccaaaat agcaaacaat aaatgagaga gtgctcttaa aacaataatt
    19321 aaaggaagtc cagctaataa aaaacctaat gtggtaccaa gagcgaccaa aattgctact
    19381 ggaatcgaca taaaaatagc caaaaacaaa ggaacatggc tcgccagagt aaaggaagct
    19441 ggtccaataa taagcttaag aggcatgatt atcggaatca aaatcgcaaa tgcgaccaaa
    19501 atagaggtat aagctattag ctgtgttggt tttttaatca ttttatctcc ttttcaaaaa
    19561 tagtatacct taaaaaccaa taactatcaa gacacctgta tcttttggta tttttaaacg
    19621 ataccttgtt gctgataaat aatcaataga atattttagc atggtattca taacaaccat
    19681 caatggcata atatactata gttatattcc tttgtataag atacctgcta attctagatc
    19741 atgcttgata gctaaaaagg cttcttgact aggacacgaa attaagtgac tatgtagtcc
    19801 ttctgtcaac gaagacaata actctgcttt agattgactg agtttggaca tgaaattagt
    19861 tacatcagag tgtgtcttaa tatttaaagg ggctgttatc ataccgtaaa taggatgttc
    19921 tacctctacc gtcgtaataa tcccttgatg agctaaaata atttctaatt cttttttagt
    19981 ttcttctaca ttatgttggc acacaatacg tgcacaaaat tggtgactat aaagcgctgt
    20041 tgacataata taaccttttg gagtcgaaat aatatcaatc tgctgagctc gaagaagagc
    20101 tatatctcca acgattattt ggcgactcac tcctaataac ttacctaaac gagtagcaga
    20161 tacagctttt tgttcactat ttaagcactc aataattttt tgacgacgat cttctgcttt
    20221 cataatctat ctatcctttt ttatttctat catatcatat ttttaagcag ggttttcttt
    20281 cttcttagga tatagaacca aaaaaccaga ccaaagtctg gtttttaagt tattcaccac
    20341 caaggtagta ttctttaaca atgttaagtt tttcatctaa ttcaaaaaca agtggtggga
    20401 agtttggaat ttccacatcc atgatttcgt catctgaaag acctttaatg tgtttcacaa
    20461 gagcgcggat tgagttacca tgtgcgccaa caaagacgtt tttaccgtca agaagagctg
    20521 gagcaatttt ttcttcccag taaggcattg cgcgttcaag agttactttt aagttttcag
    20581 catctggaat aagggctggg tctagatcag cataacgacg gtctttgtgt gctgaatact
    20641 catcatcttt agccatagct ggcggcaata cgtcgtatga acgacgccag atatgaactt
    20701 gttcatcacc aaattgttct gcagcttcag ctttgttttt gccagtcaaa gcaccatagt
    20761 gacgctcgtt caagcgccat gatttttcag ttggaaccca caattgacct gcattttcaa
    20821 gggcaaggtt agttgttttg atagcacgtg tcaatactga agtgaaagca aggtcaaatt
    20881 caatacctgc ttctttgatc aatttacctg catcaatcgc ttgttgtgtc cctttttctg
    20941 aaagatcaac atctgcccaa ccagtgaaga ggttagcttt gttccattct gactcaccgt
    21001 ggcgagcgaa aaccaatttt accatgagtt aatatctcct tttaatttaa aggttgctac
    21061 ctttttacaa ttcctatttt acaaaaaata tagcaaaaaa gctagtctat tctgacttta
    21121 ttgaaaatca taatgtgact atcatgaaaa tttcaaatgt tcgtcaataa cagtaatata
    21181 tttacatttt tgtaaaaata gcttgctatt attcatgcct agtggtagaa tagaaaaaat
    21241 ttgtctaaaa tatggaggaa ataatggttt ctactgctac acaaattggt catttctctt
    21301 ttgataactg tttgatgaat gctgctggtg tttactgcat gacaaaagaa gagcttatgg
    21361 aggttgaaaa gtctcaagcc gcttcctttg tcaccaaaac agggacgctt gaagttcgtc
    21421 caggtaatcc agaacctcgc tacgcagata ctcgtcttgg ttctatcaat tcaatgggac
    21481 tccctaataa tggttttcgc tactacttag actttgtcag tgatcttgcc aaaaccgggc
    21541 aacataaacc tcactttctc tccgttgtcg ggctatctcc tactgaaacc gaaaccattt
    21601 taaaagccat catggcttca gattatgagg gtctagtgga actaaacctt tcttgcccta
    21661 acgttccagg aaaaccacag attgcttatg attttgaaac cactgatcaa cttctagaga
    21721 acatctttac ctattacact aaacctcttg gtatcaaatt acctccttat tttgacattg
    21781 tgcattttga tcaagcggct gcgattttca ataaataccc cctttccttt gttaactgtg
    21841 tcaattctat cggaaatggg ctggtcatta aggatgaaca agtcctcatc aagcctaaaa
    21901 atggctttgg tggtataggt ggagattaca tcaaacctac tgctctagcc aatgtccatg
    21961 cgttttacaa acgcttaaaa ccttctatcc acattattgg tacaggggga gttaaaacag
    22021 gacgcgatgc ctttgaacat attctttgtg gcgccagcat ggtccaaatt gggacagccc
    22081 ttcatcaaga agggccagct atctttgaac gggtcactaa ggaacttaaa acgattatgg
    22141 tagaaaaagg ctaccaaagc ttagacgatt ttcgtgggaa cttacgttac aaagattaac
    22201 cttaatagtc aaaaaagctt ggaaatgtgc actttgtaca ctttccaagc tttttaaaat
    22261 gggaattttt ttgaagggac agcgtcactt tcttgggact gtctttgctg gttgtttgat
    22321 tcaacttttc ttttttgctt gcgctcaaat tgctgataaa aatagaaaaa tagaatgatt
    22381 ttaattattg aaaatacagc taaaccaatg atcataatag taaacatacg gcggttttct
    22441 ctttcataag tcttactatt attataaaca ctttcaagtt ttcaagcaag tttctaaatt
    22501 atttaaaaga aagtaaacgc aagccattta aaatcactaa aatcgttgag ccttcgtgtc
    22561 caacaacacc aagcggcaag ttaactacct gaaaaacatt ggctaaaatc aataaggtaa
    22621 tcacagataa ggcaaaaaca atattttgtt tgataatggt cttcattttg cgggaaagtt
    22681 gaatcgaaaa tggaatacga gtcaagtcat ccataatcac actgtctgca ctttccattg
    22741 caatatctgt tcctgatcca atagcataag aaacatctgc ttgagcaagg gcaggagcat
    22801 cattaatacc atctcctacc atagccacaa aaccatattt agtctttaat tctgctaact
    22861 tagccacctt atcttgaggc atacagttgg ctaccacttc atcaatacca agtttttgtg
    22921 ccacataatt ggcggttcgt tcttggtcac ctgttaacat gactgttttg attcccatgg
    22981 catgaagaga cttaatagca cgttttgatt ctattttgat atcatccaag agggcatagt
    23041 aagctatcaa ttgatggtca cgtgaaacaa agattagggt tttcccttga ttttcttcca
    23101 cttgaatagt ttcttcaaaa gctgataggt cttgaacctt ttccaaaatg aaggttttct
    23161 tgccaattcg ccattcttgc ccttgataga agccctgaaa acctttccca gaaatttctt
    23221 ctaagtggtc aaaggtcagt ggctccaatt tttcagtgta ttcaagaagg gctttagaaa
    23281 taggatgggt actagcagtc tctgctcctt ttaccagtct attcacgagc aactcatctt
    23341 ccaaataatg agcattcaca acagaaggtt ttccttgggt gagcgttccc gttttatcca
    23401 tgacaacagc cttaatatct cccatgttat cgacaatatc ccctcctttg ataatcaatc
    23461 cctttctggc tgcacgagaa atagcagcca agctagcagg tgtggaactg gcaattaggg
    23521 cacatggtga agctactgtt aagagaatca tccctcggta aaaagcagcc aaccaagtcc
    23581 aagaaagcac aaagtggcta aagaggataa aggcaggaat aaggacgagc acaaatttga
    23641 cataaccatc ttctaagctt tcgataaagg tggcagtttt gcttttcttt tcttgggcag
    23701 attccaccag attaataatc ttggcaaaga gagtatcgtc attttcaata gtaaccaaca
    23761 tatctatggt ttgtccttgg ttaatggttc ccccaatcag atcctggcct tctgccttat
    23821 caacagtgat aggctcacca gtgaccatag attcatcaaa ttgaccaaaa ggactaagca
    23881 actgcccgtc aattggaaca gcttcgcctt tacgaacttg taaacggtca ccaacgctca
    23941 aggatctggt ctcaacttct aaaatatggc catcttcttg gtattgacga gctgtatctg
    24001 gcgtcaagga catcaaggct gaaatagcat ccttactttt ttccatggcc atttcttcaa
    24061 gcgtattgga caacgaaaag ataaaaataa gcagagcacc ctccagccaa tagccgataa
    24121 ttccagcacc gatagctgcc aaaatcatca aaatatccac tgacaagtgt ttgttcttca
    24181 ccaaatccaa tatacccgtt tttgcagacg tatatcctcc aatcaagaag gctgtaatga
    24241 aaatagcgga agccacttgt ggaaatgagt gtaaaaaggc taggccaatt attattaata
    24301 ccaaacacgc taaagtctcc atcaaatgaa gatggtctgc catccattgt ctgattgtca
    24361 tttttagttc cctcgcaatt aaaagttatt caatctttaa gatatattaa ttataataat
    24421 tctaaataaa taagtcaagt aatttagaaa cattctaaat aaactttttt aaacttacct
    24481 tttgctttca aaaatcctaa cttcaactat ttgcaaatat gaaaaaaact ccccctacct
    24541 gcgga
//
LOCUS       DAXMQE010000027        23413 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.027, whole genome shotgun sequence.
ACCESSION   DAXMQE010000027 DAXMQE010000000
VERSION     DAXMQE010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23413)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23413)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23413
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.027"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            <1..939
                     /locus_tag="ACF4ZO_001282"
     CDS             <1..939
                     /locus_tag="ACF4ZO_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IIB"
                     /protein_id="HFD5486815.1"
                     /translation="GGGVTGTFFNQLLGSGLGGPASPGSIIAILSMVPKGGSYLAVLT
                     GVFSAALVSFLIASIILKADKSVDDESALAEAQAATQAAKAESKGQTLSSQASAQFSS
                     DDIQQIIFACDAGMGSSAMSASILRDKVKKAGLSIPVTNKAISNLTDVTNTLIVTQQE
                     LAPRAAQKTPRAVHVSVDNFLATPKYDEIVAQLAKKSSAELAKDFEQASAKEDVVDLN
                     YIDEVVFAYGENKGSATMGQATLVEIFKNRDVGIPVSKVENHQLVAFNSKNILVVTNI
                     ANQSVAQQFAPQAQLLVVDSLVTTPEYDKMIDRMHK"
     gene            965..1363
                     /locus_tag="ACF4ZO_001283"
                     /pseudo
     CDS             965..1363
                     /locus_tag="ACF4ZO_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012658494.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
     gene            complement(1365..2021)
                     /locus_tag="ACF4ZO_001284"
                     /pseudo
     CDS             complement(1365..2021)
                     /locus_tag="ACF4ZO_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284832.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
     gene            complement(2141..3463)
                     /locus_tag="ACF4ZO_001285"
     CDS             complement(2141..3463)
                     /locus_tag="ACF4ZO_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005283 - amino acid:sodium symporter
                     activity [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine/glycine:cation symporter family protein"
                     /protein_id="HFD5486816.1"
                     /translation="MIALVKLIDNLIWGPPLLILLVGTGIYLTSRLGLIQILKLPRAF
                     KLIFSDDEGHGDISSFAALATALAATVGTGNIVGVATAIKSGGPGALFWMWVAAFFGM
                     ATKYAEGVLAIKYRTKDANGHISGGPMYYIVNGMGTKWKPLAILFAGSGILVALFGIG
                     TFAQVNSITSSLGHSFGLSPQMVSIVLAIFVAAIIFGGIHSISKVAEKVVPFMAIFYI
                     LSSLAVIFSHYQQLLPVIRLVFQSAFTPTAAIGGFAGSLMKDAIQKGIARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTIIICTLTGLSILVTGQWTGQLEGAPLT
                     QSAFATVFGNLGTFGLTFSLVLFAFTTILGWSYYGERCFEFLFGITHLTYFRIVFILM
                     VGLGGFLKLELIWVLADIVNGLMALPNLIALLALSPVVILETKHYFIK"
     regulatory      complement(3591..3677)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            3991..6309
                     /gene="pcrA"
                     /locus_tag="ACF4ZO_001286"
     CDS             3991..6309
                     /gene="pcrA"
                     /locus_tag="ACF4ZO_001286"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006268 - DNA unwinding involved in DNA
                     replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HFD5486817.1"
                     /translation="MNPLLNGMNDRQAQAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKFVNPWNILAITFTNKAAREMKERALALNPATKDTLIATFHSMCVRILRREADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNIDPKKWNERSILGTISNAKNDLLDEKGYEAQA
                     ADMYSQIVARCYKAYQEELRRSEALDFDDLIMMTLRLFDANPDVLAYYQQRYQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPDAKVVL
                     LEENYRSTKKILQAANDVINNNRNRRPKKLWTQNADGEQLVYYRANDERDEAVFVAST
                     ISNMSQELGKNFKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDLIA
                     YLTIVANPADNISFERIVNEPKRGVGPGTLDKLRQFAYESDQSLLEAASNLLMSPLKG
                     KAAQAIMDLANILGQLRQDLDQMSITDLAEALLEKTGYLDSLRLQNTLESQARIENIE
                     EFLSVTKNFDESSASQEEDETGVDRLGRFLNDLALIADTDDSQAEAAEVTLMTLHAAK
                     GLEFPVVFLIGMEEGVFPLSRASEDPDELEEERRLAYVGITRAEEVLFMTNANTRTLF
                     GKSSYNRPTRFLKEISEELLSYKGLARPAQSSFGVRFSTETHTQFGQGMSLSEALQAR
                     KAQAQVRQSAQPMQAHTIPSASTSSVLPFGSNSSVEEVTWQIGDIAHHKKWGDGTVLE
                     VSGSGKTMELKIKFPEVGLKKLLASVAPIEKK"
     gene            6672..6920
                     /locus_tag="ACF4ZO_001287"
     CDS             6672..6920
                     /locus_tag="ACF4ZO_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HFD5486818.1"
                     /translation="MGLIWTLIVGALIGVIAGALTKKGGSMGWIANIAAGLVGSSVGQ
                     ALLGSWGPSLAGMSLIPSVIGAVIVVMITSFVLNKTNN"
     gene            6981..7568
                     /gene="amaP"
                     /locus_tag="ACF4ZO_001288"
     CDS             6981..7568
                     /gene="amaP"
                     /locus_tag="ACF4ZO_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HFD5486819.1"
                     /translation="MSKLLKISYCLVGLVLLSVFGWVVGITGGYIYLPYSYRWLSWGM
                     DSFPNLLDSALSYYYFWTALVLFVITFLALLVIILYPRIYTEVQLRHKNKKGTLLLKK
                     SAIESYVATAIQTAGLMPNPTVTAKLYKRKFKIIVKGRLASRVAVADQISGVKEGIEK
                     GLTEFFGINYPVNFKVYVKDIADSDRKHITRNRVE"
     gene            7579..7767
                     /locus_tag="ACF4ZO_001289"
     CDS             7579..7767
                     /locus_tag="ACF4ZO_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HFD5486820.1"
                     /translation="MEFYEKFKYPIIGGLVGLIIAILLMAFGLFKTLLAIIFIILGIY
                     GGLYAKKTGIIDQFLNRK"
     gene            7780..8319
                     /locus_tag="ACF4ZO_001290"
     CDS             7780..8319
                     /locus_tag="ACF4ZO_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HFD5486821.1"
                     /translation="MTETYIKNTSKDLTSAIRGQLTYDDKVIEKIVGLALENVDGLLG
                     VNGGFFANLKDKLVNTESVRDGVNVEVGKKQVAVDLDIVAEYQKHVPTIYDSIKSIVE
                     EEVKRMTDLDVIEVNVKVVDIKTKEQFEAEKVSLQDKVSDMARSTSEFTSHQVENVKA
                     SVDNGVEKLQDQKAEPRVK"
     gene            8360..8560
                     /locus_tag="ACF4ZO_001291"
     CDS             8360..8560
                     /locus_tag="ACF4ZO_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HFD5486822.1"
                     /translation="MSDEKYNAKLDQAGGKLKEGFGKISGDKSLETEGKVDKVTGKVK
                     EVIADAKDTVKGLAKGLDNKDK"
     gene            8571..9059
                     /locus_tag="ACF4ZO_001292"
     CDS             8571..9059
                     /locus_tag="ACF4ZO_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HFD5486823.1"
                     /translation="MEKTQIKSTLTYDDKVIEKIVGHALENVGGLLAVTGGFFSNIKN
                     NLVNSESVTDGVSVEVGSKEVAVDLAIIVEYGKDIPAIAESIKAIVSQNVDSMTHLKV
                     VEVNVNVVDIRTKEEHEAASVTVQDRVTSAASSTSQFVSEQTEKLKDTISDTVNSDEA
                     AK"
     gene            9222..9863
                     /locus_tag="ACF4ZO_001293"
     CDS             9222..9863
                     /locus_tag="ACF4ZO_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFD5486824.1"
                     /translation="MISPKKEITSSKYQKIAISVAQRIANGEYEVGEKLKSRTTIAST
                     FNVSPETARKGLNILADLKILTLKHGSGAIVLSKERAIEFINQYESTHSIAVLKEKIR
                     ETINDQGKAMEKMAVLVNDFLMQSQSVSKQYPLAPYEIICSQDSEHFGKSIGVLNIWH
                     QTGATIVAIEHAGQFIVSPGPYSVIEKGDHIYFVGDESVISRMKTFFNLRKGL"
     gene            complement(10006..10548)
                     /locus_tag="ACF4ZO_001294"
     CDS             complement(10006..10548)
                     /locus_tag="ACF4ZO_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFD5486825.1"
                     /translation="MTKRHTETKAYVKTALITLLTEQSFETLTVSDLTKKAGINRGTF
                     YLHYTDKFDMMNHFKNDTLDDLYRLLNQAEIYTDTRQVLNQTLSYLIEHREFITALAT
                     ISYLKFPQLIKDFCYQFLTTITGFQDIVTNQYHIPYPYALEVYLASIESIISYWIANG
                     YQETTEEVADIILKAVTLDN"
     gene            10666..11367
                     /locus_tag="ACF4ZO_001295"
     CDS             10666..11367
                     /locus_tag="ACF4ZO_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD5486826.1"
                     /translation="MAFIELKQVSKSYQVGETTVFANHEVSFEINKGELVVILGASGA
                     GKSTVLNILGGMDTVDAGQVIIDGKDIAHYTSKALTQYRRNAIGFVFQFYNLVPNLTA
                     KENVELAVEIVADALDPVTILKEVGLSHRLDHFPAQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDYQTGKQILTLLQDMARTKGTTVVIVTHNAAIAPIADRVIFMHDAQVTK
                     TVINKEPASIETIDY"
     gene            11382..14018
                     /locus_tag="ACF4ZO_001296"
     CDS             11382..14018
                     /locus_tag="ACF4ZO_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HFD5486827.1"
                     /translation="MIKKTLWKDILRAIKNSKGRFISLFFLMALGSFALVGLKVTGPD
                     MERTASRYLERHQVMDLTVLASHQFSQADKQELDTLKGAHLEYGHLLDVSLTSNQKSL
                     RLYSVPKKVSKPVLVKGSWPKRETDLVLSSSLAKNYQIGDELAVTSPMEGLLTTTHFQ
                     VVGFANSSEVWSKSNLGSSSTGDGSLYAYAFVNPNVFKSAFNLLRIRFSNLRLTNAFS
                     KDYQKRVTQNQAHLDNLLKDNGQKRYDDLQNQYDLALKNGRAALAKETVKLAASEENL
                     TFLEVSALQEAKHQIEQGKEALAKEEKQLEQVQATKDKLEKPSYLTYNRSTLPGGEGY
                     HTYATSTTSISNVGNIFPVVLYLVAALVAFTTMTRYVDEERTSSGLLKAIGYSNKDIS
                     LKFLIYGLLASFLGTTLGIIGGTYLLSALISEILTGALTIGKTHLYSYWFYNGIAYLL
                     AMLSAVLPAYLIVKKELFLNAAQLLLPKPPSKGPKIWLEHLTFVWKALSFTHKVTIRN
                     IFRYKQRMLMTIVGVAGSVALLFAGLGIQSSLAKVVEHQFGDLTTYDILAVGSAKATA
                     TEQTDLASYLKQEPITGYQKVSYASLTLPVKGLPDKQSISILSSSATSLSPYFNLLDS
                     QEQKKVPIPTSGVLISEKLASYYKVKPGDQLVLTDRKGQSYKVTIKQVIDMTVGHYLI
                     MSNTYFKNHFKGLEAAPAYLIKVKDKDSKHIKETASDLLTLKAIRAVSQNANHIKSVQ
                     LVVTSLNQVMTLLVFLSILLAIVILYNLTTINIAERIRELSTIKVLGFYDQEVTLYIY
                     RETISLSLVGILLGIYLGKGLHTYIMTMISTGDIQFGVKVDAYVYLVPILVILSLLAV
                     LGIWVNRHLKKVDMLEALKSID"
     gene            14110..14706
                     /locus_tag="ACF4ZO_001297"
     CDS             14110..14706
                     /locus_tag="ACF4ZO_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HFD5486828.1"
                     /translation="MENSIEAYLADSREKVTLGTVVDCFKGKAVSNKVVPGDVGLINL
                     SDMGTLGIQYHQVRTFQMDRRQLLRYLLEDGDVLIASKGTLKKVCVFHKQNRDVVASS
                     NITVLRPQKLLRGYYIKFFLDSPIGQALLDAADHGKDVINLSTKELLDIPIPVIPLVK
                     QDYLINHYLRGLTDYHRKLNRAEQEWEYIQNEIQKGLG"
     gene            14717..15673
                     /locus_tag="ACF4ZO_001298"
     CDS             14717..15673
                     /locus_tag="ACF4ZO_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HFD5486829.1"
                     /translation="MGSVERTLKMTLATIVAILIAYQLHLDYAMSAGIIALLSVLDTR
                     KSSLVVARNRLLSFFLAFGIAMMCFSLFGFTTVGFMCYLLIIIPLLYHFQIEAGLVPI
                     TVLVTHLIAKKSIALPILSNEFMLFFVGTSVALLFNAYMGPQDQQIRYYHQKVESDLK
                     GILYRFESFLLEGKGQNEGLLIKNLDKILDEALKLVYRERHNQLFQQTNYQVHYFEMR
                     RQQNRLLGQMAINVNTLMRQSKESILLSHLFHETACQLSEQNPALTLFDDIEQLLETF
                     RHGDLPQTREEFERRAVLFQLLQDLERFILLKVEFYQDYQND"
     gene            15770..17110
                     /locus_tag="ACF4ZO_001299"
     CDS             15770..17110
                     /locus_tag="ACF4ZO_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HFD5486830.1"
                     /translation="MNEIKCPHCHTLFTINESEYSQLLEQVRGQAFDEELQKRLINEI
                     ALLEEKAKHQLHEVVVKKETAITSLTNQLEQIEKEQSYLRQEELAKKDQLIASLEAKL
                     DKLASQNALELANQLAEKDKEVVSLTNQLDKLALEKDATFQSKLATIEKERDGIKNQL
                     ALQAKESELSLASVRSDYEAQLKAANEQVEFYKNFKAQQSTKAIGESLELYAETEFNK
                     VRSYAFPNASFVKDNQLSSRGSKGDYIYREVDANGVEILSIMFEMKNEADTTKTKHKN
                     SDFFKELDKDRREKDCEYAVLVSMLEADNDYYNTGIVDVSHEYQKMYVVRPQLFIQLI
                     GILRNAALNSLHYKQELALIKEQNIDITHFEEDLDQFKNAFAKNYQSASNNFKKAIDE
                     IDKSIKRMEEVKRFLTTSENQLRLANNKLEDVSVKKLTRQNPTMREKFEALKDQ"
     gene            17226..18110
                     /gene="truB"
                     /locus_tag="ACF4ZO_001300"
     CDS             17226..18110
                     /gene="truB"
                     /locus_tag="ACF4ZO_001300"
                     /EC_number="5.4.99.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HFD5486831.1"
                     /translation="MINGIINLKKEAGMTSHDAVFKLRKLLQEKKIGHGGTLDPDVVG
                     VLPIAVGKATRVIEYMTEAGKVYEGQVTLGYSTTTEDASGEVVARSSLPAVLTEELVD
                     QTMTTFLGKITQTPPMYSAVKVNGRKLYEYARAGESVERPRREVTISLFERTSPLNFT
                     EDGLCRFSFKVACSKGTYVRTLAVDLGRALGVESHMSFLQRSASAGLTLETAYTLGEI
                     ADMVSKQEMSFLLPIEYGVADLPKMVIDDTELTEISFGRRLSLPSQEPLLAAFHGEKV
                     IAILEKRDQEYKPKKVLI"
     gene            18139..19071
                     /locus_tag="ACF4ZO_001301"
     CDS             18139..19071
                     /locus_tag="ACF4ZO_001301"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003919 - FMN adenylyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HFD5486832.1"
                     /translation="MEIEYIKDYRDINQEDDTVLILGYFDGLHRGHKALFDKAREVAN
                     KEGLKVVVFTFTESPKLAFSRFSPELLLHITYPKKRYEKFADYGVNKLYLVDFTSKFS
                     KVSSDHFITHYIKKLKAKHIVVGFDYKFGHNRTDSDYLARNFEGQVYTIEEIKEDHRK
                     ISATWIRKLIQEGNVVKANHLLGYDLSTRGRVVHGDARGRTIGFPTANLAPIDNTYLP
                     ADGVYVTNVIVANKIYRSMTSLGKNVTFGGKELRLEVNIFDFDEEIYGEIIEIVWLDK
                     IRDMEKFEGIEDLTDRLEYDKRTALNWKKDSKLS"
     gene            19114..19518
                     /locus_tag="ACF4ZO_001302"
     CDS             19114..19518
                     /locus_tag="ACF4ZO_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HFD5486833.1"
                     /translation="MVTLFLSPSCTSCRKARAWLVKHEVDFQEHNIITSPLSRDELMS
                     ILSFTENGTEDIISTRSKVFQKLDIDVEELSISGLIDLIAKNPSLLRRPIIMDQKRMQ
                     IGFNEDEIRAFLSRDYRKQELRQATIKAEIEG"
     gene            19520..19798
                     /locus_tag="ACF4ZO_001303"
     CDS             19520..19798
                     /locus_tag="ACF4ZO_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HFD5486834.1"
                     /translation="MSGNYYYPLDLSWSTEEISSVLHFLNKVELAYEKKVDAKQLLDS
                     YKTYKTIVKSKAQEKQIDRDFQKVSGYSTYQVVKKAKAIEKGFFSLGN"
     gene            19788..20576
                     /locus_tag="ACF4ZO_001304"
     CDS             19788..20576
                     /locus_tag="ACF4ZO_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HFD5486835.1"
                     /translation="METKYAFARQIIKEAGLFIKSKMSEQLDIQVKTQFDDLVTNVDQ
                     ETQQLLMDRIHQTYPCDAILAEENDVRHPINQGNVWVIDPIDGTVNFIVQGSQFAVMI
                     AYYEQGIGQFGLIYDVMADQLLAGGGDFEVTLNGDKLPAYQEKPLERSLIGCNAGMFA
                     RNDRNLAHLISKTLGVRVYGGAGICMVKVMKQELLAYFSFIQPWDYAAAKVLGDKLGY
                     VLLTIDGYEPDFQTRQKIMFVPKCQLTRIASFLTKDSAVTLEDQ"
     gene            20582..21889
                     /locus_tag="ACF4ZO_001305"
     CDS             20582..21889
                     /locus_tag="ACF4ZO_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HFD5486836.1"
                     /translation="MSLPKEFINTYQAILGKELEDFLASFNQEPVNAFRINPLKNQLK
                     TFEHPIPNTLWGYYGKLSGKSPEHVSGLVYSQEPAAQMVAQVAAPQKGSRVLDLAAAP
                     GGKSTHLLAYLDNTGLLVSNEISKKRSKVLVENIERFGAKNVVVTNESADRLAKVFSH
                     YFDTIVFDGPCSGEGMFRKDPDAIQYWHHGYPAECAKLQKSILEDALTMLKPGGELIY
                     STCTWAPEENEDVVQWLLETYTFLELVDVPKLNGMVSGIGLPETARMYPHRYQGEGQF
                     VAKLKDKRQEGQSTKLKAPKSNLTKDQLRLWKMFEKDHLNLTLSGTLQTFGDYLYLLP
                     DGLPALDGLKIARNGLELGVFKKKRFEPSYALGLALKPDEVRSSIELREEDFRPYVSG
                     NVITLPQSYPTGWYQLLINGNGLGFAKVVDKTIKNNFPKGLRF"
     gene            22028..22894
                     /locus_tag="ACF4ZO_001306"
     CDS             22028..22894
                     /locus_tag="ACF4ZO_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042301 - phosphate ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HFD5486837.1"
                     /translation="MKMKKKFFLLSLLALSTFFLSACSSWIDKGESITAVGSTALQPL
                     VEAVADEFGSSNLGKTVNVQGGGSGTGLSQVQSGAVQIGNSDVFAEEKDGIDPSKLVD
                     HQVAVAGLAVIANPKVKVSNLSSQQLQKIFSGEYTNWKQVGGEDLAISVINRAASSGS
                     RATFDSVIMKGVNAKQSQEQDSNGMVKSIVSQTPGAISYLSFAYVDSSVKSLQLNGFK
                     ANAKNVATNDWPIWSYEHMYTKDKPTGLTKEFLDYMFSDEVQQNIVTHMGYISINDME
                     VVKSHDGKVTKR"
     gene            22905..>23413
                     /locus_tag="ACF4ZO_001307"
     CDS             22905..>23413
                     /locus_tag="ACF4ZO_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PstC family ABC transporter permease"
                     /protein_id="HFD5486838.1"
                     /translation="MENQELAKKLASPSKNSRLETFGRTITFLCLALIIFIVAMILIF
                     VAQKGLSTFFIDKVNLFDFLFGKEWQPSVKNAAGIPYLGALPMITGSFLVTVLSAIIA
                     TPFAIGAAVFMTEISPKYGAKLLQPAVELLVGIPSVVYGFIGLQVIVPFMRAIFGGTG
                     FGILSGVCV"
BASE COUNT         7614 a         4014 c         4795 g         6990 t
ORIGIN      
        1 ggtggtgggg ttacaggtac attctttaac caattattag gttcaggtct tggtggacca
       61 gcttcaccag gttcaatcat tgctatctta agtatggttc ctaaaggtgg aagctactta
      121 gctgttttaa caggtgtttt ctcagcagca cttgtttcat tcttaattgc ttctattatt
      181 cttaaagcag ataaatcagt agatgatgaa agcgcattgg ctgaagctca agcagcaact
      241 caagcagcaa aagcagaatc aaaaggtcaa actctttcct ctcaagcgtc agcacaattt
      301 tcaagtgatg atattcaaca aattatcttt gcttgtgatg caggaatggg tagctctgca
      361 atgagtgctt caatccttcg tgataaagta aaaaaagcag gactttcaat acctgtaaca
      421 aacaaagcta tttcaaattt aacagatgta actaacacat taattgttac tcaacaagag
      481 cttgcaccgc gcgctgctca gaaaacacca cgtgctgtcc atgtttcagt tgataacttc
      541 ttagccactc caaaatatga cgaaattgtt gctcaattag caaaaaagtc tagtgctgaa
      601 cttgcaaaag attttgagca agcttcagca aaagaagatg ttgttgattt aaattatatt
      661 gatgaagttg tatttgccta tggtgagaac aaaggttcag caacaatggg tcaggcaacc
      721 ctggtcgaaa ttttcaaaaa tagagacgtt ggaattccag tttctaaagt tgaaaatcat
      781 caactagttg ctttcaattc taaaaatatt ttagttgtca ctaacattgc taaccaatct
      841 gtagcgcaac aattcgcacc acaagctcaa ttgctagtag ttgatagtct agtaacaact
      901 ccagaatatg ataaaatgat agatcgtatg cataaataac gacaaaatgg tgtatgatga
      961 cattatgcta ctaacaaaac gtgaagaaca attattgaaa gctctcctga attatggaaa
     1021 gctttcaatt gataatatgg gagatatttt aaaagtatca agacggacgg tatatcgtgt
     1081 tttaaatgag ttgacggaca gtcttgagag tttgaatatc agtattatta aggaagatca
     1141 aaaatattat ttaacaggtg aacttgaaga attaagagca ttttcaagtc aggataattt
     1201 ctcaaaaaat gaaagactga acttgattac gtattatctt ttgatagcca atcaagaaat
     1261 cacaaatgaa ttcttacaag aaaaattagc tgtcagtaat gtcactatta ttcaggatat
     1321 tgccattgtt gagaaacgtt tggcagattt caacattcta ctcatttttt caaatgacgg
     1381 ctatcaaatc catcagataa actaaacgaa ctttccataa agatatcaaa agctgtttta
     1441 agaataaaga acgtaatgat catagcagct atatgatcga taactggtaa atgcaaagaa
     1501 gctgctataa tagcaattga tgttccgata gaagtaacag catcagctag attatcctta
     1561 gaagcagcga ctaaggcact ggattttaca cgtttggaaa gacgtttgtt aaagacataa
     1621 acccctaaca taacaaaagc tgaaacgata ccgacaatag ccccaagagg gtcaatatca
     1681 acttgctgac cactaaagat acttttaatt gtgtgaatca gtacttggaa acctacaaga
     1741 aacataataa aagaagtgac aaggctggat aaatcttcaa ttttccaatg accaaattta
     1801 tgattggcat cggctggttg actagctaag tgaagaccaa taagcagagc tacatttccc
     1861 acaatatccg ataaattgtt aaatccatca gcaataaggg aacttgcatt taacaaataa
     1921 ccagctaata atttggcaac actaagcaac aagtagacaa taatactaac gattgggccc
     1981 tttctggcta gttttaaatt tgcaatcgga tcctgtgtca taataactcc tttgatttca
     2041 actttatatt ataccataaa aaggggctta agaaaaaagc ctagcttctt gaacttggca
     2101 gaagaagact aggtataact gggtagtact aacgtaatgt ttacttaata aagtaatgct
     2161 tggtttctaa aataacaact ggcgagagag ctaggagggc aatcaggtta ggaagtgcca
     2221 ttaaaccatt gacaatatca gccaaaaccc aaatcaattc taacttaagg aagcctccta
     2281 ggcctaccat taagataaag acaatacgga agtaggtgag atgtgtaatg ccaaagagga
     2341 attcaaagca gcgttctcca taataactcc atcctaaaat cgttgtaaag gcgaagagaa
     2401 ctagggaaaa ggttaggcca aaagtcccta aatttccaaa cacagtggca aaggcagatt
     2461 gggtcagagg agccccttcg agctgcccag tccattggcc tgttactaaa atagataggc
     2521 cggttagggt acagataata atcgtatcaa taaaagttcc tgtcatggag atcagtccct
     2581 gctccacggg ttcattggtt ttagctgctg ctgcagcaat aggtgcagat cctagtccag
     2641 actcattgga gaagacaccg cgtgcaattc ctttttgaat ggcatccttc atgagacttc
     2701 cagcaaagcc tccaatagca gctgtcggag tgaaggctga ttgaaagact aaacgaataa
     2761 caggaagtag ctgctggtag tgactaaaaa taactgctaa actagataga atataaaaaa
     2821 tagccataaa aggaacgact ttttcagcca ctttggaaat ggaatgaatg ccaccaaaaa
     2881 taatggcagc cacaaagata gctaaaacaa tactgaccat ttgtggggat aagccaaagc
     2941 tatgacctaa agacgaggtg atcgagttca cttgagcaaa ggttccgatt ccaaataggg
     3001 caactaggat ccctgaaccc gcaaaaagaa tggctaaggg tttccatttt gtccccatgc
     3061 cattaacaat atagtacata ggaccaccag aaatatgacc gttggcatcc tttgtacggt
     3121 atttaatcgc tagtacccct tcagcgtact tagtggccat tccaaaaaaa gcggcaaccc
     3181 acatccaaaa gagcgctcca ggaccaccag acttgatagc agtggcaacc ccaacaatgt
     3241 taccagttcc gacagtagcg gcaagggcag ttgcaagagc agcaaaggat gaaatatctc
     3301 catgtccttc gtcatctgaa aaaatgagtt taaaggctct tggtagtttt aagatttgaa
     3361 ttaatcctaa acgactggta aggtaaatcc ccgtcccaac caataaaatt aagaggggcg
     3421 gtccccaaat aaggttatca attaatttaa cgagtgctat catctttctc tcctaaaagt
     3481 catcgaagac gccaaaagaa aaaagctatc tctttctttg agacaacttc tgaagcaatg
     3541 ataaaacagc aaacacaaaa aagactaaga ctgttcttaa tggtgtttgt attttacctt
     3601 ctgtcctttt gcctgagaga ttgagcagta tgccttgccc cttcggcgcc taataaggtc
     3661 tctccagaag tccgtccatc aaacagtccc gttcaaaaac tgaacacctg agagtataac
     3721 tccttcggcg aaaaaaattc ttctcctgca tgacatcatt cggtttatta aattaggact
     3781 atcatacctt aaaaaacgaa tgaagtcaac caaaatagca aaaaaataag gaatgcttta
     3841 agaaatcgct attattttta aatatctgat cctaaactag aaaaaggaat ctctttactt
     3901 ttggggtctt ctttgctatt tttcttggaa acatgatata attttaaggt tgataaaaga
     3961 gatgtcactg aacgagatta aggagaaagc atgaatcctt tattaaatgg aatgaatgat
     4021 cggcaggcac aagctgttca aacaactgaa ggtcccttat tgattatggc gggggctggt
     4081 tctggtaaaa caagggtact gacccatcgt attgcctatt taattgatga aaaatttgtc
     4141 aatccttgga atattttagc tattaccttt actaataagg ctgcgcgtga aatgaaagaa
     4201 agagccttgg ccttaaatcc agctactaaa gataccttaa ttgctacctt tcactccatg
     4261 tgtgtacgga ttctgcgtcg tgaggctgat cacattggtt acaaccgaaa cttcacaatc
     4321 gtggatccag gtgagcaacg aacgttgatg aagcgcattt taaaacaatt aaatatagac
     4381 cctaaaaagt ggaatgaacg ctctatttta ggaactattt caaacgctaa aaatgatttg
     4441 cttgatgaaa agggatacga ggcacaggct gctgatatgt atagtcaaat cgtagcgagg
     4501 tgttacaaag cttatcagga agaattacga cgtagcgaag cacttgactt tgatgattta
     4561 atcatgatga cgctacgcct gtttgacgct aatcctgacg tgttagctta ttaccagcag
     4621 cgttaccaat acattcatgt ggacgagtat caagatacca accatgccca atatcaatta
     4681 gtcaagttac tagcttctcg ctttaaaaat atttgcgttg ttggagacgc tgatcagtct
     4741 atctatggtt ggcggggagc tgacatgcaa aatattcttg attttgaaaa agattaccca
     4801 gatgctaagg tagtgctttt agaagaaaac tatcgctcta ccaagaaaat tctgcaagca
     4861 gctaacgacg tgattaacaa taaccgtaat cgccgtccta agaaactttg gacacaaaat
     4921 gcggatgggg aacaactggt ttattaccgg gcaaatgatg agcgagatga ggcagtattt
     4981 gtggcctcaa ccattagcaa tatgagtcaa gagcttggaa aaaacttcaa agatttcgct
     5041 gttttatacc gtaccaatgc ccaatctcgg accattgaag aagcactctt aaaatccaat
     5101 attccttaca ccatggttgg aggtaccaag ttttacagcc gtaaagaaat tcgggattta
     5161 attgcctatt taaccattgt tgctaaccct gctgataata tttcttttga gcggattgtg
     5221 aatgagccta aacgaggtgt tggtccagga acgcttgata aactgcgtca gtttgcctat
     5281 gagagtgacc agtctttatt agaagcagct tcaaatctat tgatgtcccc cttgaaaggt
     5341 aaagcagcac aagctatcat ggacttggcc aatattctcg gtcagctacg tcaagaccta
     5401 gatcagatga gtatcactga cttagcagaa gctttgttag aaaaaacagg ttatttagat
     5461 agcttacgcc tgcaaaatac tttggaaagt caggctcgca ttgagaatat cgaagaattc
     5521 ttatctgtta ccaaaaattt tgacgagtca agtgcctctc aagaagaaga cgaaaccggt
     5581 gttgatcgct tgggacgttt tttaaacgat ttagcactga ttgctgatac agatgattcc
     5641 caagcagaag ctgctgaagt aaccttaatg accctacatg ctgccaaagg cttggagttc
     5701 cctgttgttt tcttaattgg tatggaagaa ggtgtctttc ccttatcacg tgcctctgaa
     5761 gatccagatg aattggaaga agaaagacgt ttagcttatg tcggaatcac aagagctgaa
     5821 gaagttctct ttatgaccaa tgccaacacc agaaccctct ttggtaaaag tagttataac
     5881 cgtccaacac gcttcttgaa agaaatttca gaggaactac tctcttataa aggattggca
     5941 agaccagcac aatcttcatt tggtgtgcgt ttttctactg aaacacacac acagtttgga
     6001 caagggatga gcctatcaga agccttacaa gctcgaaagg cccaggctca agtaagacaa
     6061 tcagcacagc caatgcaggc acatacgata ccatcagctt caactagctc agttttaccg
     6121 tttggttcta atagctctgt agaagaggtc acttggcaga ttggcgatat cgctcaccat
     6181 aaaaaatggg gagacgggac tgtgcttgag gtttcaggct ccggaaaaac gatggaattg
     6241 aaaatcaaat ttccagaagt tggtttaaag aaattactag caagtgttgc tcctattgag
     6301 aaaaaataag aaaaaaatga gcttcctact atataagtga gtaggaagct cattttttta
     6361 gatttctgta tcatataaaa gttaaaaaat tttaagtttt aggagcatat cagttgcatt
     6421 ttaaatttaa aggtgtataa taacaatata aattaaataa cgagtggtca ctttataaaa
     6481 tattatcaaa gtaacatttt ataggatttt gaaatattgg tattcaaaca aaaaataaac
     6541 taacacttta ttatttagtt tatatagtca ctttttgaaa gtcgactatt aaaagactat
     6601 tgcttgaaga ataacagctg ttattcttcc ttggacaaaa ggtacaggag tatctaaaaa
     6661 ggagaattat catgggactt atttggactt taatcgtcgg tgcgcttatt ggtgtgattg
     6721 ctggagcact tactaaaaaa ggtggttcaa tgggctggat tgcaaacatc gctgctggtc
     6781 tagttggttc ttccgttggt caagctttac ttggttcatg gggcccttct ttagcaggaa
     6841 tgtctttgat cccgtcagtt attggtgccg ttatcgttgt tatgatcact tcttttgtac
     6901 taaacaaaac taacaactag tttcctcttt atttagtaag tacttacaaa tagagaatgt
     6961 taagtagaaa agaggtctgt atgtcaaaat tgttaaagat tagttattgt cttgtcggac
     7021 ttgttctatt gtctgttttt ggatgggtag ttggaataac cggaggctat atatatttac
     7081 cttatagtta tcgttggcta agttggggta tggatagttt tcccaatctc ttagattcag
     7141 ctttatccta ttattacttc tggacagccc ttgtattatt tgttataaca tttcttgcct
     7201 tattagttat tattttatac ccaagaattt atactgaggt ccagttacgc cataaaaata
     7261 aaaaaggaac acttttatta aaaaaatcgg ctattgaaag ttatgttgcg accgctattc
     7321 aaactgcagg tttgatgcca aacccaacag tcacagctaa attatataag cggaagttta
     7381 agattatcgt taaaggacgt ttagcttctc gtgtagcagt ggcagatcaa attagtggcg
     7441 tgaaagaagg gatcgaaaaa ggtttaaccg agttcttcgg tattaattat cctgttaatt
     7501 tcaaagttta tgttaaagat attgctgatt ctgatcgtaa acatattacc agaaatcgtg
     7561 tagaatagga gatctatcat ggaattttat gaaaaattca agtaccctat tattggtggc
     7621 ttggtggggc taattattgc catattgctc atggcttttg gtttattcaa aacgctacta
     7681 gcaattattt tcattatttt aggaatatat ggtggcctgt atgccaaaaa aacaggtatt
     7741 attgatcaat ttcttaatcg caaataaagg agacttatta tgactgaaac ttatattaaa
     7801 aacacatcta aagacttaac ttcagcaatt cgtggtcaat taacatatga tgataaagta
     7861 attgaaaaaa ttgttggttt agcacttgaa aatgtcgatg ggttactggg tgtaaatggt
     7921 ggtttttttg ctaacctaaa agataaatta gtaaacaccg aatctgtacg tgatggcgtg
     7981 aacgtggaag ttggaaaaaa acaagttgcc gttgatcttg atattgtcgc tgaatatcaa
     8041 aagcatgtgc cgactattta tgactctatt aaatcgatcg ttgaagaaga agtgaagaga
     8101 atgaccgatc tggatgtgat tgaagttaat gttaaagtag tcgacattaa aacaaaagaa
     8161 caatttgaag ctgaaaaagt aagtttacaa gacaaagttt cagacatggc acgttcaaca
     8221 tctgaattta cgagtcatca agttgagaat gttaaagctt cagtggataa cggtgttgaa
     8281 aaacttcaag atcaaaaagc tgagccacgt gtaaaataat tatatgtcgt caattaggta
     8341 agctaaagga gggtttattg tgtcagatga aaaatataat gcgaaattag atcaagctgg
     8401 tggcaagtta aaagaaggat ttggtaagat ttctggagat aaatctttag aaactgaagg
     8461 taaagtagat aaagttactg gaaaagttaa agaggttatt gcagacgcca aagatactgt
     8521 aaaaggatta gctaaaggct tagataataa agataaataa aggggacatg atggaaaaaa
     8581 ctcaaattaa aagcactctt acttatgacg ataaggtcat cgaaaaaatt gtcggtcatg
     8641 ctttggaaaa cgttggcgga ttactagctg taacaggtgg atttttctca aatattaaaa
     8701 ataatttggt gaattctgag tctgtaactg atggtgtttc agttgaagtt ggcagcaagg
     8761 aagtagcagt tgatttagca atcattgtag aatacggtaa agatattcct gctattgcag
     8821 aatctattaa agctattgtt tctcaaaacg ttgatagtat gacacatttg aaagttgttg
     8881 aagtcaatgt gaacgttgtt gatattcgta ctaaggaaga acatgaagct gctagcgtta
     8941 ctgttcaaga tcgtgtcact agtgcagctt caagtacttc acaatttgta tcagaacaaa
     9001 cagaaaaatt aaaagatact atctctgata ctgtaaatag tgatgaggca gctaaataag
     9061 caatcgtcta ggaagtatta ttgactagtg gtgataagtt tgagctggta tttaccagct
     9121 ctttttgtca cggttaaaaa gatacggact attgtcatct ctctaaaaat atgatttaat
     9181 tagatagaaa tttttcaaat tgttagaaag gagtaaatta agtgataagt cctaaaaaag
     9241 agataacaag ttcaaaatat caaaaaattg ctatttcagt agctcagcgt atcgcaaatg
     9301 gcgaatatga agtgggcgaa aagttaaagt caagaactac tatcgcctcg acatttaatg
     9361 tatcaccaga aacggctcgt aaaggcctga atattttagc tgacttgaaa attttgactt
     9421 taaaacatgg tagtggagct attgtgctgt caaaagaaag agctattgag tttataaatc
     9481 aatacgaatc aacccattcc atcgctgttt taaaagaaaa aatacgtgag actattaatg
     9541 atcagggaaa agcaatggaa aaaatggctg ttttggtcaa tgatttttta atgcaaagtc
     9601 aatctgttag taagcaatac ccattagcac cttatgagat tatttgtagt caagattcgg
     9661 aacattttgg caaatctatt ggtgtgttaa atatctggca ccagacagga gcaactatcg
     9721 tcgctattga acatgctggt cagtttatcg tttcaccagg tccttattct gttattgaaa
     9781 aaggcgatca tatttatttc gttggtgatg agtcagtcat ttcacgaatg aagacctttt
     9841 ttaatttacg aaaaggatta taagtttgag ggcccacctc aaactttttt tgttgctgtt
     9901 gagcattatt aaaagaggca gatcatcatg gtttgtcttt ccaaaatatc tgtttagaca
     9961 gttgttttgg attgggagca tgatttcaga ctcttttgat gttttttaat tgtctagagt
    10021 aactgctttg agaataatat cggcaacctc ttcagtggtt tcttgatagc cattagcaat
    10081 ccaatagctg ataatgctct caatactggc aaggtaaact tctaaagcat agggataagg
    10141 aatatggtat tgattggtca caatgtcttg gaaaccagta atagtagtca aaaattggta
    10201 acagaaatcc ttgatgagtt gcggaaattt gaggtaagaa atagtagcga gtgcggttat
    10261 aaattctcta tgttctataa ggtaggacaa ggtttgattg aggacttgtc gagtgtctgt
    10321 gtagatttca gcctgattta acaaacggta caaatcatcc agagtgtcat ttttgaagtg
    10381 attcatcatg tcaaatttat cagtgtagtg gaggtagaag gttcctctat tgataccagc
    10441 ctttttagta aggtcagaga cagtaagagt ttcaaaagat tgttcagtta gtaaggtgat
    10501 taaggcggtc tttacataag ctttggtttc agtatgtctt ttggtcattc tcaggtgctc
    10561 cttaaatcaa cagttgcgtc agatttgttc ttgttaaata cttagggcca ttatataata
    10621 aggctataat taaatcaaca ctatgttcaa ataatggagg ggcagatggc ttttattgaa
    10681 ttaaaacagg tttcaaaatc ttatcaggta ggagagacga ctgtttttgc caaccacgaa
    10741 gtgtcttttg agattaataa aggagaacta gtggttattt tgggagcatc cggagctggt
    10801 aaatcgacag tcctcaatat tttggggggc atggacacag tagatgcagg tcaagtaatt
    10861 attgatggca aagacattgc tcattacacg tctaaggcct taactcagta tcgtcggaat
    10921 gctattggtt tcgtttttca attttataat ttggttccta atttgacagc taaagaaaat
    10981 gttgaattag cagttgaaat tgtagcagat gctttagatc ctgtgaccat tttaaaggaa
    11041 gtaggactca gtcatcgtct ggatcatttt cctgctcagc tctcaggtgg tgaacagcaa
    11101 cgggtttcga tagcacgtgc cttagctaaa aaccctaaat tgcttctttg tgatgaacct
    11161 acaggtgccc ttgactacca aacaggaaag caaattctaa ccctcttaca ggatatggca
    11221 cgaactaagg ggaccacggt agttattgta acccacaatg ctgctattgc tccgatagct
    11281 gatcgtgtca tttttatgca tgatgcacag gttaccaaga cagtcattaa taaggaacct
    11341 gcaagcattg agacaattga ttattaagag gaaggtgtcg tatgataaag aaaaccttat
    11401 ggaaggatat tttgagagct atcaagaata gtaaagggcg attcatttcc ttatttttcc
    11461 taatggcctt aggctccttt gctttagttg gacttaaagt caccggtcca gatatggaac
    11521 gaacagccag ccgttacctc gaaagacacc aggtgatgga cctaacggta ctggcttctc
    11581 atcaattttc ccaagccgat aaacaagagt tagatacgtt aaaaggggct catttagaat
    11641 atggtcattt acttgatgtc agtctaacta gcaaccagaa atctcttagg ctctatagcg
    11701 tgccaaagaa agtgtctaag ccagtcttgg ttaaagggag ttggccaaag cgagagacag
    11761 atttggtttt atcctcctca cttgctaaaa actatcagat tggagatgaa ctagcagtca
    11821 cctcacctat ggaaggtttg ctgacgacaa cccattttca agtggttggt tttgcgaatt
    11881 cttcagaagt ttggtccaag tccaatttag gaagttcctc aaccggagat ggaagtctct
    11941 acgcttatgc ttttgttaat ccaaacgttt tcaaaagtgc ctttaacctg ctgcgcatcc
    12001 gttttagtaa tcttcgtctg acaaacgctt tttccaaaga ctatcaaaaa agggtaaccc
    12061 aaaaccaagc tcatttggat aatctactta aagataatgg ccagaagcgt tatgatgacc
    12121 tccaaaatca gtatgacctt gccttaaaaa atggcagagc agcacttgca aaggaaacag
    12181 tgaaactagc tgcgagtgag gagaacttaa cttttttaga agtctctgct ttacaagaag
    12241 ctaagcatca gattgaacaa ggcaaagaag cattagccaa ggaggaaaag cagttagagc
    12301 aggtgcaggc tacaaaagat aagctagaaa aacccagtta cctgacttat aatcgctcga
    12361 ccctaccagg aggagaagga tatcatactt atgcaacttc aacgacctcc atttcaaatg
    12421 ttggaaatat ttttcctgtt gttctttatc tcgtagctgc tctagtagcc tttaccacca
    12481 tgacacgtta tgttgatgaa gaaagaacaa gctctggtct attaaaagcc attggttatt
    12541 ctaacaagga tatcagttta aagtttctta tctatgggct tttagccagt tttttaggga
    12601 caactttagg tattattggg ggaacttacc tcttatctgc cttgatttca gagatcttaa
    12661 caggagcttt gactattgga aagactcacc tttatagtta ttggttttat aatggcatag
    12721 cttacttgct ggctatgtta tctgctgttt taccagccta cttaattgtc aaaaaggaat
    12781 tattcctcaa tgcagctcag ttattgctgc ccaaacctcc tagtaagggg ccaaaaatct
    12841 ggttggaaca ccttactttt gtctggaaag ccctgtcctt tactcacaag gtgaccatac
    12901 gtaatatttt tcgctataaa caaagaatgc tgatgaccat tgtaggcgtt gcaggctcag
    12961 tagccctttt atttgcaggc ttagggattc agtcgtcatt agccaaagta gttgagcatc
    13021 aatttggtga tttaacgact tatgatattt tggctgtcgg ttcggccaaa gcgacagcga
    13081 cagagcaaac tgacttagct agctatctta aacaagaacc tattacaggg taccaaaagg
    13141 tatcttatgc cagcttaacc cttcctgtaa agggattacc tgataagcaa agtatttcca
    13201 ttttatcaag ttcagctact tctcttagcc cctattttaa tctgctggat agtcaggagc
    13261 aaaagaaggt tcccattcca acctctggtg ttttgatttc tgagaaatta gcctcctatt
    13321 acaaggtaaa accaggtgat cagttggtat tgactgatcg gaaaggacag tcttataaag
    13381 tgacgattaa acaggttatt gacatgacag ttggccatta cctgataatg tctaatacct
    13441 attttaagaa tcattttaaa ggattggagg ctgctcctgc ctatctgatt aaggtaaaag
    13501 acaaagatag caagcacata aaggagacag ccagtgactt gttaacctta aaagcgatta
    13561 gagcagtttc acaaaacgcc aatcatatta aatctgttca gctagtagtc acctctctta
    13621 atcaggtcat gaccctcctt gtcttcttgt ctattttatt agcaatcgtt atcctttata
    13681 acttaacgac tattaatatt gctgagcgta ttcgagaatt atccactatt aaagttctgg
    13741 gattttacga tcaggaggtc accttatata tttatcgaga aactatttcg ctatccctag
    13801 taggcattct tttaggtatc tatttaggaa aaggcctgca tacttatatc atgacaatga
    13861 tttcaactgg ggatattcaa tttggtgtaa aggttgatgc ttatgtttat ctagtgccaa
    13921 ttctagtaat ccttagcttg ttagcggtat taggtatctg ggttaatcgc catttaaaaa
    13981 aggttgatat gttagaagct ttgaaatcca tagattgatt ggtgaaaaga cagatataga
    14041 cagcacttga aaagttaatc atattatgat agtatctaaa tactataatt taatagaaag
    14101 atactatgta tggaaaatag cattgaggcc tatctagcag atagcagaga aaaggtaaca
    14161 ttaggtacag ttgttgattg ttttaaagga aaagcagtct caaataaggt tgtgccaggt
    14221 gatgtgggat tgattaattt atctgacatg ggcaccttag ggattcaata tcaccaagta
    14281 agaactttcc agatggatcg taggcagctc ttgcgttacc ttttggaaga cggagatgtc
    14341 ttaatcgcct ctaagggaac cctaaaaaaa gtctgtgttt ttcataagca aaatcgagat
    14401 gtggtggcat catcaaatat cactgtctta cgccctcaaa aactgttaag gggctactat
    14461 atcaagttct ttttggactc acctattggt caagcgctct tggatgcagc ggaccatggc
    14521 aaagatgtga tcaatctctc aacgaaagaa ttgttggata ttccaattcc cgttattcct
    14581 ttagtgaaac aggactattt gattaatcac tacttgagag gattaacaga ttatcatcgt
    14641 aaactcaatc gagcagaaca ggagtgggaa tatattcaga atgaaattca aaaaggatta
    14701 ggttaggagt cttgtcatgg gttcagttga acgtacatta aaaatgacct tggctaccat
    14761 tgttgccatt ttaattgctt accaacttca tctggattat gcaatgtcag cggggatcat
    14821 tgccctgtta agtgttttag acacccgtaa gtccagtttg gtggtcgcta ggaatcgctt
    14881 gctatctttt ttcctggctt tcgggattgc gatgatgtgc tttagcttgt ttggttttac
    14941 gacagtaggt tttatgtgtt atttgttaat tattattcct ttgctctatc actttcagat
    15001 agaggcagga ctggttccta taacagtact tgtgacacat ttgattgcta aaaagagtat
    15061 tgcattacct attttatcga atgagtttat gctctttttt gtagggacta gtgtcgcttt
    15121 actatttaat gcttatatgg gtccacaaga tcagcaaatt cggtactatc accaaaaagt
    15181 tgaatcggat ctgaaaggta tcttataccg ttttgaaagt tttctactgg aaggaaaagg
    15241 tcaaaatgaa ggactcttga tcaaaaacct tgataaaata ttagatgaag ctctaaaact
    15301 agtttatcga gaaaggcata atcaactatt tcagcagacc aattatcaag ttcattattt
    15361 tgagatgcga cgacaacaga atagactatt gggacaaatg gctatcaacg taaacacgtt
    15421 aatgagacaa agtaaggaaa gtattctttt gtcacatctt tttcacgaaa ctgcttgtca
    15481 gctaagcgaa caaaatccgg ctttaacctt gtttgatgat atcgaacaat tgcttgaaac
    15541 ctttcgtcat ggtgatcttc ctcaaactcg ggaggaattt gagcgacgtg cggttttatt
    15601 tcagctctta caagacttgg aacgttttat cttattaaag gtagagtttt atcaggatta
    15661 tcaaaatgac taaatctcta ttgcacactt cttatctatg acagcttggg acttaacttc
    15721 ctgagctttt ttgctataat aaaaacaaga atctcagaat ggagacaaga tgaacgaaat
    15781 aaaatgccct cattgtcata ccctatttac tatcaatgag tcagagtata gtcaattatt
    15841 ggaacaagtc agagggcaag cctttgatga agaattgcaa aaacggctaa tcaatgagat
    15901 agccttgctg gaagaaaaag cgaagcatca attgcatgag gttgtcgtaa aaaaagaaac
    15961 agctattacc agcttgacaa accaattaga gcaaattgaa aaagaacaat cctacctcag
    16021 acaagaagaa ctggctaaaa aagaccagct tattgcttct ttagaagcga aacttgataa
    16081 attagcctcg caaaatgctt tggaactggc caatcaatta gctgagaagg acaaagaagt
    16141 ggttagtttg accaatcagc tggacaaatt agcacttgaa aaagatgcca cgttccagtc
    16201 aaaacttgct acaatcgaaa aagaacgcga tggaatcaaa aaccaattgg cgcttcaagc
    16261 taaagaaagt gaattgtcgt tggcttcggt gcgcagcgac tacgaagcac agttaaaagc
    16321 ggctaacgag caagttgaat tttataaaaa tttcaaagcg cagcaatcta ccaaagcaat
    16381 cggagagagt ctagaactct atgctgaaac agagttcaat aaagtaagaa gctatgcttt
    16441 tcccaatgct agctttgtca aagataacca attgtctagt cgtgggtcaa aaggggacta
    16501 tatttaccga gaggttgatg ccaatggtgt agaaatcctc tctatcatgt ttgagatgaa
    16561 gaacgaggca gacaccacca aaacaaaaca taaaaatagt gattttttca aggagttaga
    16621 taaagaccgt cgcgaaaaag attgtgagta tgctgttttg gtaagcatgt tagaagctga
    16681 taatgattac tacaatacag ggattgttga tgtcagtcat gagtatcaaa agatgtatgt
    16741 ggttcgtcct caactcttta ttcagttgat agggattctg cgaaatgcag ccctgaatag
    16801 tttacattat aagcaagagt tggccttgat taaggaacaa aatattgaca tcactcactt
    16861 cgaagaggat ttggatcaat ttaagaatgc ctttgctaag aactatcagt ctgccagcaa
    16921 caactttaaa aaggctattg acgagattga taaatcgatt aaacgcatgg aggaagtgaa
    16981 acgcttttta accactagtg aaaatcagtt acgcttagct aataataaat tagaggatgt
    17041 ttcagttaaa aaactgaccc gccaaaaccc aaccatgcga gagaaatttg aagccctcaa
    17101 ggaccagtaa gcctgaaagt gagtctttcc ttgctaaaat tggttaagcg tttattttgg
    17161 caaaactgat gataaagcgg tagaatagaa tcagtaacaa ttactaatta gagagaaaaa
    17221 tagacatgat aaatggaatc attaatttaa aaaaagaagc cggcatgacc tctcatgacg
    17281 cagtttttaa attacggaag ttattacaag aaaaaaagat tggacatggg gggacattag
    17341 atcctgatgt ggtcggtgtt ctaccaattg cagttggtaa ggctactcgt gtgatcgaat
    17401 acatgacaga agctggtaaa gtttatgaag gacaagtgac tctcggttac tcaacaacga
    17461 ctgaggatgc tagtggagag gtagttgcga gatcctcttt gccagctgtg ctaacagaag
    17521 aactcgttga tcaaacgatg acgactttcc ttgggaaaat cacacagacc ccacctatgt
    17581 attcagccgt aaaggttaat ggccgtaaat tgtacgagta tgcgcgtgct ggtgaaagtg
    17641 tggaacgtcc tagaagagaa gtgactattt ctctgtttga acgcaccagc cctttgaatt
    17701 ttactgaaga cggtctttgc cgattctctt ttaaagttgc ttgtagcaag gggacttatg
    17761 tgcggacctt agcagttgat ttaggtcgag ctctaggggt agagagtcat atgtctttct
    17821 tgcagcgatc agcttcagca ggattaaccc tcgagactgc ctatactttg ggagaaattg
    17881 ctgatatggt ttctaaacaa gagatgtctt ttttgttacc gatcgagtat ggcgttgctg
    17941 atcttcctaa aatggttatt gatgatactg aattgactga aatttcattt ggtcgccgtc
    18001 ttagtctccc tagtcaagag ccactgttag ctgcttttca tggcgaaaaa gtaattgcta
    18061 ttttagaaaa aagagatcaa gaatacaaac ccaaaaaagt tcttatttaa atagtttgag
    18121 taagtagaat ggataattat ggaaattgaa tatatcaaag attatcgtga tattaaccaa
    18181 gaagatgata cagtcttgat attgggatat tttgatggat tacaccgtgg tcataaagcc
    18241 ttatttgaca aagcaagaga ggttgcaaat aaagaagggt taaaagtagt cgtttttacg
    18301 tttacagagt ctccgaaatt ggctttttcg cgtttttctc ctgagttatt gcttcatatt
    18361 acttatccaa agaagcgtta tgaaaaattt gccgattacg gtgtaaataa attatatttg
    18421 gttgatttta cttctaaatt ctctaaggtc tcatctgatc attttataac tcattatatt
    18481 aaaaaactga aagcaaagca tattgttgtc ggttttgact ataagtttgg gcataatcgt
    18541 acagatagtg attatttagc cagaaatttt gaaggacaag tttataccat tgaggaaata
    18601 aaagaagatc atcgaaaaat ttctgctaca tggataagga agcttattca agaaggtaat
    18661 gtagttaaag caaaccactt gttaggctat gacttatcga caagggggag agtcgttcac
    18721 ggggatgcgc gtggccgtac tattggtttc ccaacagcca atctagctcc aattgacaac
    18781 acatacttac cagctgatgg agtctatgtt acaaatgtta ttgttgctaa taaaatctat
    18841 cgctctatga caagtttagg taaaaatgtg acatttgggg ggaaagagtt gcgtctagaa
    18901 gttaacattt ttgactttga cgaagagatc tatggagaaa ttattgagat tgtttggtta
    18961 gataagattc gagacatgga aaaattcgag ggaatcgaag atttgactga tagattggaa
    19021 tatgataaac gaacagcatt aaattggaaa aaagatagca aattatctta aatttttgta
    19081 taataaggta agtaaatttg atagaggaaa aatatggtta ccttattttt atcacctagc
    19141 tgtaccagtt gtcggaaagc aagggcatgg ttagtaaaac acgaagttga ctttcaagag
    19201 cataatatta ttacaagtcc attaagccgt gatgaattaa tgtcaatcct ctcttttaca
    19261 gagaatggaa cggaggatat tatttcaaca cgttcaaagg tttttcaaaa acttgatatt
    19321 gatgtagaag agctttcaat ttcaggttta attgatttaa ttgctaaaaa tccaagtctt
    19381 cttcgtcgcc ctattatcat ggatcaaaaa cgcatgcaaa ttggttttaa tgaagatgaa
    19441 attagagcgt ttttatcgag agattatcgc aagcaagaac tacgtcaagc aacgataaaa
    19501 gcagaaattg aggggtgata tgtcaggtaa ttattattat ccacttgact taagttggag
    19561 cactgaagaa atatcctcag tgcttcattt tttgaataaa gtggagttag catatgaaaa
    19621 aaaagtagat gcaaaacaac tactagatag ttataagact tataaaacca ttgtcaaaag
    19681 taaagctcag gaaaagcaaa tcgaccgtga ttttcaaaaa gttagtggtt attcgaccta
    19741 tcaagttgtt aaaaaagcga aggcaattga gaaaggattc ttttcccttg gaaactaaat
    19801 acgcatttgc aaggcaaatc attaaagaag cagggctttt tatcaagtca aaaatgtcag
    19861 agcagctaga tattcaggtg aaaacacaat ttgatgatct ggttaccaat gttgatcaag
    19921 aaactcaaca gttactgatg gatcgtattc atcagaccta tccttgtgat gccattttag
    19981 ctgaagaaaa tgacgttcgt caccccatta atcaaggaaa tgtttgggtc atcgatccca
    20041 ttgatggaac ggttaacttt attgtgcagg gatcacagtt tgcagtgatg attgcctatt
    20101 atgaacaagg aattggtcaa tttgggctta tttatgatgt gatggcagat caattactag
    20161 ctggtggtgg tgattttgaa gttactttaa acggtgataa gcttccagct taccaagaaa
    20221 aacctttaga gcgtagctta attggctgca atgcaggcat gtttgccaga aatgatcgta
    20281 accttgctca tctaatttca aagactttag gtgtaagggt ttatggtggt gcaggtatct
    20341 gcatggttaa ggtcatgaag caggaattac tggcctattt ttcatttatc caaccatggg
    20401 attacgcagc agcaaaagta ctaggcgata aactgggtta tgttttacta actattgacg
    20461 gatatgagcc tgattttcaa acacgtcaaa aaatcatgtt tgttcctaaa tgccaactca
    20521 ctaggatagc gtcttttcta acaaaggact ctgccgtcac acttgaagat caatagaaat
    20581 gatgtcatta ccaaaagaat ttattaacac ttatcaagca atactaggca aagaattaga
    20641 agatttcttg gcaagtttta accaagagcc ggtcaatgct tttcggatta accccttaaa
    20701 gaatcaacta aaaacctttg aacaccccat tccaaatacc ttatggggat attatggtaa
    20761 actatctggc aagtctccag agcatgtgtc ggggttggtt tattcccaag aaccagcggc
    20821 tcaaatggtg gcacaagtag cggctcctca aaaggggagt cgtgttttag acttggcagc
    20881 tgcaccagga ggaaaatcaa ctcatttatt agcttattta gacaatacag gtcttttagt
    20941 cagcaatgaa atttctaaga agcgcagcaa ggttttagtt gaaaatatcg aacgttttgg
    21001 tgctaaaaat gttgtggtga ctaatgaatc cgcagatcgt ttagccaagg tattttctca
    21061 ttattttgat actatcgtct ttgatggacc atgttctggt gaaggaatgt ttcgcaagga
    21121 ccctgatgct attcaatatt ggcatcacgg gtatcccgca gaatgcgcca agttgcaaaa
    21181 atctatttta gaagacgcct taaccatgtt aaaaccagga ggagaattga tatactccac
    21241 ctgtacttgg gctcctgaag aaaatgaaga tgttgtgcag tggctcttag agacttatac
    21301 ctttttagaa ttggtcgatg ttccaaaact aaatggaatg gttagtggta tcggacttcc
    21361 agagactgct agaatgtacc ctcatcgtta tcaaggggaa gggcaatttg tggccaagct
    21421 aaaagataag cgtcaagaag gacaaagcac taaactaaaa gcacctaaat ccaacttgac
    21481 caaagaccag ttacgtcttt ggaaaatgtt tgaaaaagac catctaaacc ttaccctatc
    21541 aggaacacta caaacctttg gtgattacct atacctcttg ccagatggtc ttcctgcttt
    21601 agatggcctt aaaattgctc ggaacggttt agaattaggc gtcttcaaga agaaacgctt
    21661 tgaaccctct tatgccttgg gattagcttt aaagcctgat gaggtccggt catctattga
    21721 gcttagagag gaagacttta gaccttatgt gtcaggtaac gtcattactt tgccccaatc
    21781 ttatccaaca ggctggtacc aattactcat taatggcaat ggtctaggat ttgccaaggt
    21841 cgttgacaag accatcaaaa ataatttccc taaagggtta agattttagc gtaaaaaata
    21901 agattaaaat gttaaatatt taaagaaaaa atgctttcaa agcataggta gatatgttac
    21961 tataaagaat atgtggcact tagtttctac atatataccc tttattttta cgaataggaa
    22021 ataaataatg aaaatgaaaa aaaaattctt tttgttaagt ctcttggccc tatcaacttt
    22081 ctttttatcc gcatgttcta gctggattga taaaggtgag tcaataaccg ctgtaggatc
    22141 aacagcacta caacccttag tagaagcagt agctgatgaa tttggaagca gtaatctagg
    22201 caagactgtc aatgttcaag gtggtggttc aggtacaggg ttgtctcaag ttcaatcagg
    22261 agctgtccaa attggaaata gtgatgtctt tgcagaagaa aaagatggta ttgatccttc
    22321 taaattagtt gatcatcaag tagctgttgc aggacttgca gttattgcca atcctaaagt
    22381 caaggtttcc aatctcagta gtcagcagtt gcaaaagatt ttttcaggag aatataccaa
    22441 ttggaaacaa gttggaggag aagatcttgc gatttcagtg atcaaccgag cagcaagttc
    22501 tggctcacga gcaacctttg acagtgttat catgaaaggg gtcaacgcta aacaaagtca
    22561 agagcaagac tccaatggga tggttaaatc gattgtttca caaacaccag gtgccatttc
    22621 ttacctttcc tttgcctacg ttgattcatc tgttaaatct ttgcaattaa atgggtttaa
    22681 ggcaaatgct aagaatgtgg ctacaaatga ttggccaatc tggtcctacg aacacatgta
    22741 caccaaagat aaaccaacag ggttgaccaa ggaatttctt gattatatgt tttcagatga
    22801 agtacaacag aacattgtta cacatatggg atatatttcg ataaatgata tggaagtggt
    22861 caaatctcat gatggaaaag taacaaaaag gtaatggagg aattatggaa aatcaggaat
    22921 tggctaaaaa attagcctca ccatcaaaga attcaagact tgaaaccttt ggccgcacca
    22981 ttacgttttt gtgtctggct ttgattattt ttatcgttgc gatgattctg atcttcgttg
    23041 ctcaaaaagg gttgtcaacc ttctttattg acaaggttaa tctttttgat ttcttgtttg
    23101 gaaaggagtg gcaaccaagt gtgaaaaatg cggccggcat tccttatctt ggtgctctgc
    23161 caatgattac aggatccttt ttggttaccg ttttatctgc tattattgcc accccatttg
    23221 ccattggcgc agccgttttt atgactgaaa tctcacctaa atatggtgct aaattattac
    23281 agcctgcggt tgagcttttg gttggaattc cttcggttgt ttatgggttt atcggtttgc
    23341 aagtgattgt tccttttatg cgcgctatct ttggtggcac aggttttgga atcctatctg
    23401 gggtctgtgt ctt
//
LOCUS       DAXMQE010000028        22425 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.028, whole genome shotgun sequence.
ACCESSION   DAXMQE010000028 DAXMQE010000000
VERSION     DAXMQE010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22425)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22425)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22425
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.028"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            complement(<1..1143)
                     /locus_tag="ACF4ZO_001308"
     CDS             complement(<1..1143)
                     /locus_tag="ACF4ZO_001308"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HFD5486839.1"
                     /translation="MNQGKIITVSGPLVVASGMQEANIQDICRVGHLGLVGEIIEMRR
                     DQASIQVYEETSGIGPGEPVVTTGCPLSVELGPGLISEMFDGIQRPLDRFQKATDSDF
                     LIRGVAIPSLDRKAKWAFIPKLSVGQEVVAGDILGTVQETAVIEHRIMVPYKVSGTLV
                     AIHAGDFTVTDTVYEIKQEDGSIYQGSLMQTWPVRQSRPVAQKLIPVEPLVTGQRVID
                     TFFPVTKGGAAAVPGPFGAGKTVVQHQIAKFANVDIVIYVGCGERGNEMTDVLNEFPE
                     LIDPNTGQSIMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYSVAIMADSTSR
                     WAEALREMSGRLQEMPGDEGYPAYLGSRIAEYYERAGRVRTLGSQER"
     gene            complement(1344..1664)
                     /locus_tag="ACF4ZO_001309"
     CDS             complement(1344..1664)
                     /locus_tag="ACF4ZO_001309"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HFD5486840.1"
                     /translation="MTKTLYKVGVIGNRDVILPFQMIGFQTFPVIKPQDAINQLRQLA
                     MEDFGIIYITEDIAAAIPEALTHYDNQVLPAVLPLPTHQGAQGIGLSRIQAMVEKAVG
                     QNIL"
     gene            complement(1661..2659)
                     /locus_tag="ACF4ZO_001310"
     CDS             complement(1661..2659)
                     /locus_tag="ACF4ZO_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046961 - proton-transporting ATPase
                     activity, rotational mechanism [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HFD5486841.1"
                     /translation="MPTFLELNTTISVKEKELLTKEQFDKLLQAPNTTTLARLLHQSV
                     YHLTVDDLNDLDRLESILMAELTKTYRWAFAETPQPDIVQLFTLRYTYHNVKVLLKAK
                     ASQADLSHLLLPIGDKPLAALEHLIRTMTSDEFPKEVVTEIQSIWVEYQDYQDIRVLE
                     IGTDLAYFKALKQIAQRLEDPVFQQAVLIVIDLYNLITVRRAKSQNKPISFMMQLLSD
                     EASRPSKTFITLEDDKDLMTWFENVTPDSYMTALKPYSEKLRQGTLQTTELEYLVDEC
                     LYHLFAKAKYQVDGPYVLARFLLAKSFEVKNLRLLAAALANDLPKECVIERMRPIA"
     gene            complement(2675..3259)
                     /locus_tag="ACF4ZO_001311"
     CDS             complement(2675..3259)
                     /locus_tag="ACF4ZO_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase V"
                     /protein_id="HFD5486842.1"
                     /translation="MNDITQLRQNVLEKAHQEGQQCLKIATDSLDTDFKERQQQGLHD
                     LKAKRQKELKALEQQFQVAQQQLKNQERQALLALKQDGIKELFEASLEKMTNFSKEEE
                     LAFLKQVLSKYPEQPLQVTFGEKTGQKFSSYDCAELRLAFPQLSYNQELIPQEAGFLV
                     SLDQVDDNYLYRYLLESVLKEESSRIIDMLFSEI"
     gene            complement(3328..3807)
                     /locus_tag="ACF4ZO_001312"
     CDS             complement(3328..3807)
                     /locus_tag="ACF4ZO_001312"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HFD5486843.1"
                     /translation="MEHLAHYFTAHGGVFFAALGIVLAVALSGMGSAYGVGKGGQAAA
                     ALLKEEPEKFTSALILQLLPGSQGIYGFAIGILIWMKLTPELSVNQGLAYFLVSLPIA
                     IVGYFSAKHQGNVSVAGMQILAKRPKDFMKGVILAAMVETYAILAFVVSFILLNKIG"
     gene            complement(3809..5809)
                     /locus_tag="ACF4ZO_001313"
     CDS             complement(3809..5809)
                     /locus_tag="ACF4ZO_001313"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HFD5486844.1"
                     /translation="MAISQMKKLAMVFEKDYLDLVLKTLQQSQLVEVRDMKQLKHWQD
                     AFNKGNVKLPQIVQYDLTHQKPLLDDEALQYLLQSQQELENGLASLSAFLPPIGKLTA
                     LRQKTPSLSFKQFEERHRQQAAQTALKMMSQKIERLEQLQNKIDQLTEYCQELEKWRS
                     LTVLPQDLAQFHFLSARVGTIPSTANDHFYHQLKQHKGLFIEEVYHTEFEYGLVLFWQ
                     AQDTIHLQKYQFKPLLYKEQLLPSEQLRINKELLTNWLAEKDSLLKELRQSQKILAQL
                     QVEIDYVLSQYQRQQTKKQLLGTRHLIALEGWIEADSVNQLKGLMTKTLGDMFYLDSY
                     DVTPDDWEDVPIKLRNHRYIAPFELVTEMYALPKYQEKDPTPFLAPLYLTFFGMMVAD
                     LGYGLLLYAVTLAALVFFNLQKTSKRLVTFFNILAISVAIWGLIYGSFFGFDLPVALL
                     STKTDVITILVVSLLFGFVTLIFGLLLGAWQQVRMKAYATAYTSSLAWTFILLGLLLF
                     ILGKNVSGLAYLSVIGKWLALGNAFGILVVSLLKSKSLLGLGSGLYNLYGISSYLSDL
                     VSFTRLMALGLSGASIGAAFNMIVGIFPPVTRFTVGIFIFILLHAINIFLSMLSGYVH
                     GARLIFVEFFGKFYEGGGKAFNPLKLADNYVNVNEETDLEDN"
     gene            complement(5799..6119)
                     /locus_tag="ACF4ZO_001314"
     CDS             complement(5799..6119)
                     /locus_tag="ACF4ZO_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486845.1"
                     /translation="MNTLLSLMNSIEQEARTIYDSYDAKKKALADKKEEELKQLFLEY
                     EQETQLLLEAKREVFFEANRQEQKASKKRLATQQLALHAILEEHKLTVVRELVDKVVE
                     TYGH"
     gene            complement(6573..7592)
                     /locus_tag="ACF4ZO_001315"
     CDS             complement(6573..7592)
                     /locus_tag="ACF4ZO_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFD5486846.1"
                     /translation="MDIIIGTSLLILVLAIFSLFNYKAPHGAKAMGALASAACASFLV
                     EAFQDSFFGKVLGFQFLSEVGGANGSLSGVAAAILVAIAIGVSPGYAVLIGLSVSGTG
                     IIPGFVAGYVVSFLIKWMEKNIPGGLDLISIIIVGAPLTRFLAQLITPVINSTLLTIG
                     DILTSSANSNPIIMGMILGGTIVVVATAPLSSMALTAMLGLTGIPMAIGALSVFGSSF
                     MNGVLFYRLKLGERKDNIAFAIEPLTQADVTSANPIPIYVTNFVGGAACGVLIALMKL
                     VNDTPGTATPIAGFAVMFAYNPVAKVLITALGCIIISLIVGYIGGSVFKNYRLVTKQE
                     LQARN"
     gene            complement(7629..7994)
                     /locus_tag="ACF4ZO_001316"
     CDS             complement(7629..7994)
                     /locus_tag="ACF4ZO_001316"
                     /EC_number="3.5.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HFD5486847.1"
                     /translation="MKSYPEPMGPYSTYTIEGHFLYTAGQLPLNPVTGQLSDGFEAQC
                     RQVFVNLQSILAEQKLDLNHIYKLNVYLTDVTNVEILNHVMTDLFEEPYPVRTAVQVS
                     ALPLQALIEVEAVARVKQL"
     gene            8168..8848
                     /locus_tag="ACF4ZO_001317"
     CDS             8168..8848
                     /locus_tag="ACF4ZO_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0140110 - transcription regulator activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HFD5486848.1"
                     /translation="MDKETLNYWKTVITFLHDVLGDNYEIILHVIDKNDIYIGELVNS
                     HISGRSKQSPLTTFALDLITNKVYKEKDFVTNYKAIVSPQHKEVRGSTFFIKDKKGNL
                     EGMLCINLDISAYQGVARDLLKLVNLNLEHFIPTAKEPKTVTPQPEEAVEILTSNIQD
                     IIGQIIDPSLLRHNVHLSQDVKIDIVAKLYEKGVFQLKGAVSKVADILCISEPSVYRY
                     LKKIEADQ"
     gene            complement(8966..9616)
                     /locus_tag="ACF4ZO_001318"
     CDS             complement(8966..9616)
                     /locus_tag="ACF4ZO_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008410 - CoA-transferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacid CoA-transferase subunit B"
                     /protein_id="HFD5486849.1"
                     /translation="MAVALSKEEIQNRIAKRVAKELEDGTLVNLGIGLPTKVANFVPE
                     EMTVYFQSENGFIGLGPKSDDPNSTIVNAGGQPVTVYPGAAFFNSADSFGIIRGGHVD
                     LTVLGALEIAENGDIANYLIPGKMVPGMGGAMDLLVGAKKVIVAMEHTNKEKHKLLKE
                     CTLPLTAKGVVDLIITEMGVFKVTPDGIQVIEISEGFTFDEVQAATGVPLSIAEGE"
     gene            complement(9619..10278)
                     /locus_tag="ACF4ZO_001319"
     CDS             complement(9619..10278)
                     /locus_tag="ACF4ZO_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008410 - CoA-transferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase subunit A"
                     /protein_id="HFD5486850.1"
                     /translation="MKENKRIAIAEAISHIKDGDTIMVGGFMANGTPEALIDALVDKG
                     TKDLTLICNDAGFVDRGVGKMVANHQFKTIYATHIGLNKEAGRQMTAGETTIELIPQG
                     TFAEKIRIGAYGIGGFYTPTGVGTLVAEGKETKTIKGKTYLLEYPFEADVALIFANKA
                     DEMGNLQYSGSENNFNQLMAACAKTTIVQAREIVPVGTIQPECVHTPHIFVDYIVKEG
                     V"
     gene            complement(10290..11474)
                     /locus_tag="ACF4ZO_001320"
     CDS             complement(10290..11474)
                     /locus_tag="ACF4ZO_001320"
                     /EC_number="2.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HFD5486851.1"
                     /translation="MTKEVVITSAYRTPIGNFGGVFKSLSAVDLGVTVVTKILADTGL
                     KSDAIDEVIFGNVLHAGLGQNVARQVALNAGLSYDTPAFTIDMVCGSGLKAVELGAQK
                     IQTGNADIVLVGGTENMSQAPYVLQGQRWGSRMGDSKVVDTMLKDGLSDAFAGYHMGI
                     TAENIVQQYGLTREEQDAFAADSQRKAQLAIEKGRFKEEIAPVTIPQRKGEPLLIDQD
                     EYPKFGTTVDKLAKLRPAFIKDEGTVTAGNASGINDGAAAILLMSKEKAEELGLPILA
                     KITSYASAGVDPSIMGCGPIPATKKALAKAQLTIDDIDLIEANEAFAAQALAVSRDLG
                     FDNEKVNVNGGAIALGHPIGASGARILVTLLAEMAKRDVRHGLATLCIGGGQGQSIIV
                     TR"
     gene            11595..12507
                     /locus_tag="ACF4ZO_001321"
                     /pseudo
     CDS             11595..12507
                     /locus_tag="ACF4ZO_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993827.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LysR substrate-binding domain-containing
                     protein"
     gene            complement(12575..13981)
                     /locus_tag="ACF4ZO_001322"
     CDS             complement(12575..13981)
                     /locus_tag="ACF4ZO_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00366 family protein"
                     /protein_id="HFD5486852.1"
                     /translation="MNNIKTKKRFMDRYIDGFMKWMPESLFICFILTFLVVTMSVLMT
                     DSPFIGTEKTGGIIYGWVNGFWGLLSFAMQMTILLATGNAVASSPPAHKMFKSLAKLP
                     QTRTQIFIFSIVVGSIFGFLHWGLGMMVAIVFGKELLVQARQKGIKVHTPLFVATLFF
                     TFLPATSGLSGAAVLYSATPDYLRNSVADAYKQVVPESVPLTESVLNLPFISLLVVCM
                     LVPLCFALLAHPKDETKIMELDDEIYHHSLDTASHVVIARNTPAEKMNASRLVMYLVG
                     GAIVSYSLYHFSVVGLSGLDLNSFNFLFLGLGLLLCGQQGPEYYGSLFKDGVMSSWGL
                     VLQFPFYAGIFGIIQSTGLGLEISHFFVAISNGTTWPVFAYLYSALLNIAVPSGGSKF
                     VIEAPYIVPATIEVGNDLGKILQAYQLGDATTNLIVPFWALSYLSNFKLKFNQIVAYT
                     IPCVLVVTGIAIIYLFVF"
     gene            14334..14999
                     /locus_tag="ACF4ZO_001323"
     CDS             14334..14999
                     /locus_tag="ACF4ZO_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486853.1"
                     /translation="MKRCNKYLFTSLLAASMLFSSYKSVHAHDNIDEEGKVHLYWQGN
                     YYVDNYVDYTKKLVDNDKNIEWTVTFNSTKEQWVYPDFSVFLPKGVKAPKEITYEHHY
                     GNGTVHSETRSNTQWHYNWENQQTNFNQEFDKFPGYTGWSTSLDKFYKLKNDGKFSHV
                     LVDTYGRQSHTYFSHKMVWKFKTELEDNYKDKWNKLPFIAGIKQNNPLAASFPSYKGE
                     FGE"
     gene            complement(15194..16036)
                     /locus_tag="ACF4ZO_001324"
     CDS             complement(15194..16036)
                     /locus_tag="ACF4ZO_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HFD5486854.1"
                     /translation="MTERLKNLGILLLFLLGTAIFLYPTLSSQWNAYRDRQLLSTYHK
                     QVIQKKPSEMEEVWQKAKAYNARLGIQPVPDAFSFRDGIHDKNYESLLQIENNDIMGY
                     VEVPSIKVTLPIYHYTTDEVLTKGAGHLFGSALPVGGDGTHTVISAHRGLPSAEMFTN
                     LNLVKKGDTFYFRVLNKVLAYKVDQILIVEPDQATSLSGVMGKDYATLVTCTPYGVNT
                     KRLLVRGHRIAYHYKKYQQAKKAMKLVDKSRMWAEVVCAAFGVVIAIILVFMYSRVSA
                     KKSK"
     gene            complement(16107..17756)
                     /gene="tee6"
                     /locus_tag="ACF4ZO_001325"
     CDS             complement(16107..17756)
                     /gene="tee6"
                     /locus_tag="ACF4ZO_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_023077982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FCT-1 pilus major pilin T6"
                     /protein_id="HFD5486855.1"
                     /translation="MREKILITAKKLMLACLAILAVVGLGMTRVSALSKDDTAQLKIT
                     NIEGGPTVTLYKIGEGVYNTNGDSFINFKYAEGVSLTETGPTSQEITTIANGINTGKI
                     KPFSTENVSISNGTATYNARGASVYIALLTGATDGRTYNPILLAASYNGEGNLVTKNI
                     DSKSNYLYGQTSVAKSSLPSITKKVTGTIDDVNKKTTSLGSVLSYSLTFELPSYTKEA
                     VNKTVYVSDNMSEGLTFNFNSLTVEWKGKMANITEDGSVMVENTKIGIAKEVNNGFNL
                     SFIYDSLESISPNISYKAVVNNKAIVGEEGNPNKAEFFYSNNPTKGNTYDNLDKKPDK
                     GNGITSKEDSKIVYTYQIAFRKVDSVSKTPLIGAIFGVYDTSNKLIDIVTTNKNGYAI
                     STQVSSGKYKIKELKAPKGYSLNTETYEITANWVTATVKTSANSKSTTYTSDKNKATD
                     NSEQVGWLKNGIFYSIDSRPTGNDVKEAYIESTKALTDGTTFSKSNEGSGTVLLETDI
                     PNTKLGELPSTGSIGTYLFKAIGSAAMIGAIGIYIVKRRKA"
     gene            complement(17795..20905)
                     /gene="fctX"
                     /locus_tag="ACF4ZO_001326"
     CDS             complement(17795..20905)
                     /gene="fctX"
                     /locus_tag="ACF4ZO_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FCT-1 pilus minor subunit FctX"
                     /protein_id="HFD5486856.1"
                     /translation="MYSRLKRELVIVINRKKKYKLIRLMVTVGLIFSQLVLPIRRLGL
                     QMISTQTKVIPQEIVTQTETQGTQVVATKQKLESENSSLKVALKRESGFEHNATIDAS
                     LDTESQGDNSQRSVTQAIVTMALELRKQGLSIVDTKIVRIQSSTNQRNDITTTLTFKN
                     GLSLEGASTEANDPNVRVGIVNPNDTVQTITPTIKQDADGKVKNLVFTGRLGKQVIIV
                     STTRLKEEQTISLDSYGELVIDGAVGLSQKDRPPYSKPITVNILKPKLSSIESSLDSK
                     DFEIVKTIDNLYTWDDQFYLLDFISKQYEVLKTDYQSAKDSTPQTRDILFGEYTVEPL
                     VMNKGHNNTINIYIRSTRPLGLKPIGAAPALIQPRSFRSLTPRSTRMKRSAPVEKFEG
                     ELEHHKRIDYLGDNQNNPDTTIDDKEDEHDTSDLYCLYLDMTGKKNPLDILVVVDKSG
                     SMQEGIGSVQRYRYYAQRWDDYYSQWVYHGTFDYSSYQGESFNRGQIHYRYRGIVSVS
                     DGIRRDDAVKNSLLGVNGLLQRFVNINPENKLSVIGFQGSADYHAGKWYPDQSPRGGF
                     YQPNLNNSRDAELLKGWSTNSLLDPNTLTALHNNGTNYHAALLKAKEILNEVKDDGRR
                     KIMIFISDGVPTFYFGEDGYRSGNGSSNDRNNVTRSQEGSKLAIDEFKARYPNLSIYS
                     LGVSKDINSDTASSSPVVLKYLSGEEHYYGITDTAELEKTLNKIVEDSKLSQLGISDS
                     LSQYVDYYDKQPDVLVTRKSKVNDETEILYQKDQVQEAGKDIIDKVVFTPKTTSQPKG
                     KVTLTFKSDYKVDDEYTYTLSFNVKASDEAYEKYKDNEGRYSEMGDSDTDYGTNQTSS
                     GKGGLPSNSDASVNYMADGREQKLPYKHPVIQVKTVPITFTKVDADNNQKKLAGVEFE
                     LRKEDKKIVWEKGTTGSNGQLNFKYLQKGKTYYLYETKAKLGYTLPENPWEVAVANNG
                     DIKVKHPIEGELKSKDGSYMIKNYKIYQLPSSGGRGSQIFIIVGSMTATVALLFYRRQ
                     HRKKQY"
     gene            complement(21232..21372)
                     /locus_tag="ACF4ZO_001327"
                     /pseudo
     CDS             complement(21232..21372)
                     /locus_tag="ACF4ZO_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            complement(22171..>22425)
                     /locus_tag="ACF4ZO_001328"
     CDS             complement(22171..>22425)
                     /locus_tag="ACF4ZO_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HFD5486857.1"
                     /translation="TQTGMSGFSETATVVEDTRPKLVFHFDNNEPKVEENREKPTKNI
                     TPILPATGDIENVLAFLGILILSVLSIFSLLKNKQSNKKV"
BASE COUNT         6862 a         4695 c         3737 g         7131 t
ORIGIN      
        1 acgttcttga cttcccaagg tccgaacacg accagcccgt tcataatatt cggcaatacg
       61 actccctaag taagccgggt agccttcatc accaggcatt tcttgtaggc gtcctgacat
      121 ctcgcgcaga gcttctgccc aacgtgatgt cgagtctgcc atgatagcca cagaatagcc
      181 catatcacgg aaatattcgg caatggtaat gcctgtgtaa atcgacgctt cacgcgctgc
      241 tactggcata ttagaggtgt ttgcaattaa caccgtgcgc tccataatgg actggcctgt
      301 atttggatca attaactctg gaaactcatt caaaacgtcg gtcatctcgt tgccgcgttc
      361 cccacaaccg acataaataa caatatcaac gttggcaaat ttagctattt gatgctgcac
      421 aactgttttt cctgccccaa atggtccagg aacagcagcg gcaccacctt ttgtaacagg
      481 gaaaaaggtg tcaataaccc gttgacctgt aaccaaaggc tcgactggga taagcttttg
      541 agcaacaggg cgactttgac gaactggcca agtctgcatg aggctacctt ggtaaatgga
      601 accgtcttcc tgcttaattt cataaactgt atctgttact gtgaagtcac ctgcatgaat
      661 agccaccaag gtccctgaaa ctttataagg aaccatgata cgatgctcaa tgacagctgt
      721 ttcttgcaca gttcctaaaa tatcacctgc aactacttct tgaccaacac ttagcttggg
      781 aataaatgcc cacttagcct ttcgatcaag acttgggata gccacaccac ggattaaaaa
      841 gtcgctgtcc gttgcttttt gaaaacgatc aagcggtcgc tgaataccgt caaacatttc
      901 tgaaatcagg cctgggccta actcgaccga caaaggacaa ccagtagtca ctactggttc
      961 tcctggaccg atccctgatg tttcctcata aacctgaata gacgcttgat cgcggcgcat
     1021 ttcaataatt tctccgacta atccaagatg tcccacacga caaatatctt gaatattagc
     1081 ttcttgcatc ccagaagcca caacaagagg tcccgaaacg gttattattt ttccttggtt
     1141 cacctttttc ctcctttatt ttttccaaat catactaact aatctatact gtcaaggttt
     1201 aatgtgacta ttttgaatag tcagcaaact atcctatgcg ttcagctgct aacttcatca
     1261 attttcctgt ccttgcattt catcagttag ctactcataa gcctcaaaca gagtataagt
     1321 cctctttgcc taacgtctta gtgttataaa atattttgac cgacagcctt ttcaaccatg
     1381 gcttgtatgc gtgacaggcc tatcccttgc gctccttgat gagttggtaa tggtaggact
     1441 gctggtagaa cttgattgtc atagtgagtg agggcttctg gaatagctgc agcaatatct
     1501 tctgtgatat aaataatacc aaagtcttcc attgctagtt gacgcaactg gttaatagcg
     1561 tcttgtggtt ttattactgg aaaagtttga aacccaatca tctgaaaagg tagaataaca
     1621 tctctgttac caattacccc gactttatac aatgttttgg tcatgctatt ggtctcatcc
     1681 tttctatgac acattctttg ggtaaatcat tagctaaagc agccgctaaa agccgtaggt
     1741 tttttacttc aaacgattta gcgagcaaaa aacgagcaag cacataaggt ccatcgactt
     1801 gatatttggc cttcgcaaat aaatggtaaa ggcattcatc aacaaggtat tctaactcag
     1861 tcgtttgaag agtgccttgg cgaagtttct ctgaataagg ttttagggct gtcatatagc
     1921 tatcaggtgt tacattttca aaccacgtca tcagatcctt atcatcttca agtgtgataa
     1981 atgttttact tggtctactt gcttcatcag ataataactg catcatgaaa cttattggtt
     2041 tattttgcga tttggcccgt ctgacggtaa tcagattata caaatcaatc acaataagaa
     2101 cagcttgttg gaaaacaggg tcctctaatc tttgtgctat ttgtttcaac gccttaaaat
     2161 aagctaagtc agtaccaatt tctaagacgc gtatgtcttg ataatcttga tattcgaccc
     2221 aaatggactg gatttctgtt accacctctt ttggaaactc atcagaagtc atcgtcctaa
     2281 tcaaatgttc caaagccgcc aaaggcttgt caccaattgg tagtaataag tgactcagat
     2341 ctgcttgact agctttagct tttaacaaca ctttgacatt atgataggtg taacgcaagg
     2401 taaataattg tactatgtca ggttgagggg tttctgcaaa agcccagcga taggtcttgg
     2461 ttagctcagc cattaagata gattctagcc gatccaaatc gttgagatcg tcaacagtta
     2521 ggtgatagac tgactggtgc aacagtcgag ctaaggttgt tgtattggga gcctgcaaca
     2581 gcttatcaaa ttgctcttta gtcaataact ctttttcttt gacactgata gtagtgttta
     2641 attctagaaa tgttggcatc gctagtcaaa cctcctatat ctctgaaaaa agcatatcaa
     2701 tgatgcggga gctttcttct ttaagaactg attctaaaag gtaacggtat aaataattgt
     2761 catcgacttg gtctaaactg actaaaaatc ctgcttcctg aggaattagc tcttgattat
     2821 agcttaattg aggaaacgct aatctcagct cagcacaatc ataagaactg aacttttgcc
     2881 ctgttttttc tccaaaagta acttgcaatg gctgttctgg atatttagac aagacttgct
     2941 tcaaaaaagc caattcttct tccttagaaa agttcgtcat cttctccaaa gaagcttcaa
     3001 atagctcctt tataccgtct tgttttaatg ctagtagagc ttgtctttct tgatttttga
     3061 gttgctgctg cgcaacctga aattgctgtt caagagcttt taactctttt tgacgctttg
     3121 cttttaaatc gtgtagtcct tgctgttgac gctctttaaa gtcagtatca agactatctg
     3181 tcgctatctt taggcactgt tgaccttctt gatgtgcttt ttcaagaaca ttttgtctta
     3241 actgtgttat atcattcacc taatttcctc cttttgatag tgttagtggt gccaccgttt
     3301 tttaaaatct agataaggac cgttacctta tccaatttta tttaagagaa taaaggagac
     3361 gacaaaggca agaatagcat aggtttcaac catagctgct aaaatgacac ccttcataaa
     3421 atctttaggg cgcttagcca agatttgcat accagctaca gaaacattgc cttggtgctt
     3481 ggccgaaaaa taaccaacaa tagcaattgg aagagatacc aaaaagtagg ctaatccttg
     3541 gttaactgaa agttctggtg tcagtttcat ccaaattaaa ataccaatag caaagccgta
     3601 gattccttga ctaccgggta acagttgcaa gataagcgca gacgtgaatt tttcgggttc
     3661 ttcttttaag agcgcagctg ccgcttgacc acctttaccg acaccataag ctgagcccat
     3721 gccactaaga gctacggcta aaacaattcc taaggctgcg aagaaaacgc caccatgtgc
     3781 tgtaaaataa tgtgctaaat gttccatgtt aattgtcctc caaatctgtt tcttcattga
     3841 cattgacata attatcagct aactttaaag gattgaaagc ttttcctcca ccttcataaa
     3901 attttccaaa aaactctacg aaaataagac gagcaccatg cacatatcct gaaagcattg
     3961 ataagaaaat attgatcgca tgcaaaagaa taaaaataaa gatacctact gtaaagcgcg
     4021 tgactggtgg aaaaatccca acaatcatgt taaaagccgc tccaatacta gctccagaaa
     4081 gccctaatgc cattagacga gtaaagctaa ccaaatcact taagtaagag ctaatgccat
     4141 ataaattata taatccacta cctagaccta aaaggctttt gctttttagt aaagaaacaa
     4201 ccaaaatccc aaaggcattg cccaatgcaa gccacttacc aataaccgat aagtaagcaa
     4261 ggccagatac attcttacca agaataaata acagcaggcc taataaaata aaagtccaag
     4321 ctagacttga cgtataggcc gtagcatatg ctttcatcct tacttgttgc catgctccta
     4381 acaaaagccc aaatataagt gtaacaaacc caaatagcaa agaaacaacc aaaatagtaa
     4441 tcacatccgt tttagttgat aataatgcca caggtaagtc aaaaccaaag aaagaaccgt
     4501 aaataagccc ccatatggct actgaaatag ctaaaatatt aaagaaggtc actaaccgtt
     4561 tactggtttt ttggagatta aaaaagacca atgcagctag tgtcacagca tatagcaaca
     4621 aaccatagcc caaatcagct accatcatgc caaaaaaagt aaggtataaa ggagctaaaa
     4681 aaggtgtcgg atctttttct tgatattttg gcaaagcgta catttctgta accaattcaa
     4741 acggtgcaat gtagcggtga ttacgtagct taatgggaac atcttcccaa tcgtctggcg
     4801 tgacatcgta actatccaga taaaacatat cacctagtgt cttagtcatt agccctttta
     4861 attggttaac cgaatcagct tctatccacc cttctaaggc tattagatgt cttgtaccga
     4921 gtaattgctt tttagtttgc tgccgttgat actgactaag gacatagtct atttcaacct
     4981 gtaactgtgc cagtatcttt tgagactgcc taagctcttt tagtagacta tctttttcag
     5041 ctagccaatt cgttagtaac tctttgttta tacgaagttg ttctgatggc agtagctgtt
     5101 ctttatataa taagggttta aactgatatt tctgtaaatg aatcgtatct tgtgcttgcc
     5161 aaaataagac aaggccgtac tcaaattctg tatggtatac ttcctcaata aaaagacctt
     5221 tgtgctgctt tagctgatga taaaaatgat catttgctgt actaggaatc gttccaactc
     5281 ttgccgacaa aaaatgaaat tgcgctaagt cctgaggcaa aacagtcaag gaacgccact
     5341 tttctaactc ctgacagtat tctgttagct ggtctatttt gttttgcagc tgctctagtc
     5401 gttctatctt ttgtgacatc attttcaaag ccgtttgagc tgcttgttgt cgatggcgtt
     5461 cttcgaactg tttaaacgaa agagatggcg ttttttgtct caaggctgtt aactttccta
     5521 ttggtggtaa aaacgctgat aagctagcaa ggccgttttc taactcttgt tggctttgta
     5581 aaaggtattg taaagcttca tcatctagta gaggtttttg atgcgtcaga tcgtattgga
     5641 cgatttgtgg caacttgacg ttgcctttgt taaaagcatc ttgccaatgt tttagttgct
     5701 tcatgtcacg aacttcaact aattgagatt gttgaagtgt ttttaaaaca agatcaagat
     5761 aatctttttc aaaaaccatt gccagctttt tcatttgact aatggccata tgtctccacc
     5821 accttatcca ctaactccct aacaacggtt agcttatgct cttctaaaat ggcatgaagg
     5881 gctagctgtt gcgtcgctaa cctctttttt gaagcttttt gttcttgacg attagcttca
     5941 aaaaacacct cacgtttagc ttctaatagt agctgagttt cttgttcgta ctcaaggaac
     6001 agctgcttta actcttcttc ttttttgtca gctagagctt ttttcttagc atcgtaactg
     6061 tcataaattg ttctagcctc ttgttcgata ctattcatta gtgacaatag ggtattcatc
     6121 acatatcaac tccttatctt tatctattgc taattctttg actcactagg tacttaaaaa
     6181 caaagctaca agaaaggcta cttttggggg ttaatcaacc agcgactata agctagagct
     6241 aaatctctaa cctatctact aacagctttt ttgagatagg ataattgctt gattaagcga
     6301 acagtatctt caagttaagc gctttcaatt ctatccataa aaacaatggc ttagttcaga
     6361 aaaaggttag ctaaaaacct gtcaaagcag taagatgaca cagaactcta aagctttgta
     6421 ttgctgtctt tcgtgtatta tcttatactt ctttaggcat ttagtaacct tgatctagtt
     6481 gacggtaagg aacctttacc agccaatagc caagccaatg tgataacagt ataactgcta
     6541 tcgtgttaaa agtcctgtca aaaagatgtt tattagtttc tcgcttgtaa ttcttgtttt
     6601 gttactaaac ggtaattttt aaagacagaa cctccaatat aacccacaat taagctgata
     6661 ataatacatc caagggctgt tatcaacact ttagcgacag gattataggc aaacatcacc
     6721 gcaaaaccgg caatcggagt agctgtccct ggcgtatcat taaccaattt cattagggcg
     6781 atcaaaacac cacatgcagc accaccaaca aaattagtca cataaatcgg aatgggattg
     6841 gctgacgtca catctgcctg agtcaacggt tcaatagcaa aagcaatatt gtcttttctt
     6901 tcacccaatt ttaatcggta aaaaagaaca ccattcataa aagaagagcc aaagacagat
     6961 aaggcaccta tagccatcgg aatacctgtc agaccaagca tggctgtcaa agccattgat
     7021 gacagcggag ctgttgctac aacaacaatc gtaccgccta atatcattcc catgataata
     7081 gggttgctat tagcacttga ggtcaggatg tctccaatag tcaataaagt actattgatc
     7141 actggcgtaa ttaactgcgc caagaaacga gttaatggtg caccgacaat aataatcgag
     7201 attaaatcaa gcccaccagg aatatttttt tccatccact tgattaaaaa agataccaca
     7261 tacccagcca caaaacctgg gataatacct gttcctgaaa ctgacaaacc aatcaaaacg
     7321 gcataacctg gagacacacc aattgcaatg gcaaccaaga tagcagcagc tacccctgat
     7381 aatgagccat ttgctccgcc tacttcactt agaaactgaa agcctaaaac cttaccaaaa
     7441 aaagaatctt gaaaggcttc aactaaaaaa gaggcacaag ctgccgaagc caaagctccc
     7501 attgccttgg caccatgagg agccttatag ttaaacaagc taaaaatagc taaaacaaga
     7561 atcaaaagac ttgttccaat aataatatcc ataatctatt ccaccaatct atctcattac
     7621 ataagacact ataactgctt cactctggca acagcttcga cttcaatcaa agcttgcaaa
     7681 ggaagcgccg acacttgaac cgctgtccga acagggtaag gctcttcaaa caaatcagtc
     7741 atgacatgat ttaatatttc cacattggtc acatctgtta aatacacatt tagcttatag
     7801 atatgattca agtccaactt ttgctctgcc aaaatagatt gtaaattaac aaaaacctgg
     7861 cgacactgtg cctcaaaacc atctgacaat tgacctgtca ctggattaag gggtaattgg
     7921 cctgcggtgt atagaaaatg tccttcaatc gtataagttg aataagggcc cattggttct
     7981 gggtagctct tcatatacga acctcctcat tgataatata gttaaatttt acaggaaacc
     8041 gcattcacag tcaataataa attctctttt tgataaaaaa ttattattaa ggtgattggc
     8101 aattgttttt tagtctaaaa tgtattacta tatttgtaaa taagaagata gatataggaa
     8161 gtttgacatg gataaagaaa cgctaaacta ctggaaaacg gttatcacat ttcttcacga
     8221 tgtcttaggt gataactatg aaattatttt acatgtgatt gataaaaatg atatctatat
     8281 tggagaactc gttaatagtc atatcagtgg acggtctaaa cagtctcctc tcaccacctt
     8341 tgctcttgat ttgattacta ataaagtcta taaggaaaaa gattttgtga ccaattacaa
     8401 agcaatcgtt agtcctcagc acaaagaagt tcggggatct acttttttta ttaaagataa
     8461 aaagggtaat ctcgagggaa tgctatgtat taacttagat atttcagcct atcaaggagt
     8521 agctagggac ctcttaaaac ttgtcaatct caatttagaa catttcatcc caactgctaa
     8581 agaacctaaa acagtcacac cccagccaga agaagctgtt gaaattttaa cctctaacat
     8641 ccaagatatt atcggtcaaa ttattgatcc ctcgttactg agacacaatg tacatcttag
     8701 ccaagatgtc aaaatagaca ttgttgccaa gctttatgaa aaaggagtct ttcaactaaa
     8761 aggagccgtc tcaaaagtcg ctgatattct atgtatttcc gaaccaagtg tttaccgcta
     8821 ccttaaaaaa attgaagccg atcaataacc aaatcaccat aaaacgccag ttaaaagtat
     8881 ttcagataag catcacaatc tctgatatac cgatgactga cgttttttta ctcaatatgc
     8941 ctttatggca agaaaaggct actagtcatt caccttcagc tatgcttaga ggtacacctg
     9001 tcgcagcttg aacctcatca aaagtaaacc cttcactgat ttcaattact tggataccat
     9061 ctggcgttac tttaaacaca cccatttctg tgataataag gtcaaccaca ccttttgctg
     9121 ttaaaggtaa ggtacattct tttaggagct tatgcttttc tttattggta tgctccatag
     9181 ctacgatgac ttttttagca ccaactaata aatccatcgc tcctcccata ccaggaacca
     9241 ttttgcctgg aatcaggtaa ttggcgatat ctccattttc tgcaatttct aaagcaccca
     9301 agacggtcaa gtcaacatga ccaccacgta taatgccaaa agaatctgca ctattaaaga
     9361 aagcggctcc tggataaacc gtcacaggct gtcctcctgc attaacgata gtcgaattcg
     9421 gatcatctga cttaggacct agtccaataa acccattttc agattgaaaa tacactgtca
     9481 tttcttcagg cacaaaattt gctactttgg ttggtagacc aatacctaaa tttaccaaag
     9541 taccatcttc taattctttg gctacacgct ttgcaatacg attttgaatc tcttctttac
     9601 ttaatgcaac cgccataact atactccttc tttaacaatg taatctacaa aaatgtgtgg
     9661 tgtatgaacg cattctggtt gtatggtgcc gactggtact atttctcgcg cctgaacaat
     9721 tgttgttttt gcacaagctg ccatcaattg attaaaatta ttttcagaac cactatactg
     9781 taaatttccc atttcatcag ctttattagc aaatatcaag gcgacatctg cctcaaatgg
     9841 gtattctaag agataggttt ttcccttgat ggtttttgtt tccttgcctt ctgccactaa
     9901 ggttcctacc cctgttggcg tgtaaaagcc accaatgcca taagctccga tgcgaatttt
     9961 ttcggcgaag gttccttgag gaataagctc aatcgtcgtt tcaccggcag tcatttggcg
    10021 cccagcttct ttatttaatc caatatgtgt tgcataaatg gttttgaatt gatgattagc
    10081 caccattttt ccaacaccgc gatcaacaaa accagcatca ttacagatca aggttaagtc
    10141 ttttgtgcct ttgtcaacca gtgcatcaat taacgcttct ggtgttccat tagccataaa
    10201 accaccgacc ataatcgtgt caccatcttt aatatgactg atagcttctg ctattgctat
    10261 tcttttattc tctttcatac ggttaccttc tatcttgtta cgatgatact ttgaccttgg
    10321 ccaccaccaa tacaaagcgt tgctaagcca tgtctcacat cacgcttagc catttctgct
    10381 aataaggtga ctaaaatacg agcacctgat gctccaatcg ggtgacccaa agcaatagct
    10441 cctccattga cattaacttt ttcattgtca aaaccaaggt ctcgtgaaac cgctaaagcc
    10501 tgagcagcaa aagcttcgtt tgcttcaatc aaatcaatgt catcaattgt cagctgagcc
    10561 tttgcaagag cctttttcgt agcaggtatt ggtccgcagc ccataatact tgggtctaca
    10621 cctgcacttg cataactagt gattttagct aaaataggga gccctaattc ttcagctttt
    10681 tctttactca tcaataaaat tgccgctgct ccatcattga ttcctgaagc attaccagca
    10741 gttactgtcc cctcatcttt gataaaagca gggcgtaact ttgctaactt atccactgtc
    10801 gttccaaatt tagggtattc atcttgatca atgagcaaag gttcaccttt acgctgagga
    10861 atagtgacag gtgcaatctc ttctttgaaa cgaccttttt ctatggcaag ttgggcttta
    10921 cgttggctat cagctgcaaa ggcatcttgt tcttctctgg tcagtccata ctgttgcaca
    10981 atattttcgg ccgttatacc catgtgataa cctgcaaaag catcactcaa cccatcttta
    11041 agcatggtat ctactacttt actatctccc atacgagatc cccaacgttg gccttgtaaa
    11101 acgtaaggtg cttgactcat gttttcggta ccaccgacta aaacaatatc agcgttgccc
    11161 gtttgaatct tttgagcacc taactcaact gcttttaagc cagaaccaca gaccatatca
    11221 atcgtaaaag caggggtatc ataagaaagc cccgcattta gcgctacttg ccgagcaaca
    11281 ttttgaccca gacctgcatg taacacattc ccaaagatca cttcatcaat ggcatcactt
    11341 ttaagaccgg tatcagctaa aatttttgta acaactgtca cccccaaatc tacggctgat
    11401 aaagatttaa agactcctcc aaaatttcct atcggggtac gataagcaga tgtgatcacc
    11461 acttctttag tcatagaaac ttctcctttt tcattattga aacgcttaca tttttattat
    11521 ataatgtgaa ctataataaa caaatatcgt ttttttatat atgctataac taaacgttat
    11581 cgaaagagga aaatatgaat atttcaagct tggcttattt tattgagatt gttaattgtg
    11641 actttaactt aaccaaagca gcccaaaaaa gtcatatttc gcaacccgcc cttagtagtt
    11701 atatcaagac tatcgaaaaa gaagaaggag tcgttttatt ccagcgtcaa aaagggcgtc
    11761 tagttggact aacctcagtc ggcgaacgct tttttgaaaa tgctaaggtg gttatcgcat
    11821 cacatgagca attaatggct gatttgcgga gtgaatccaa aaaatacaaa ggagaaattt
    11881 caatcggtat tcctcaactc atctctggca ttgttttttc tgagctcatt ccaaaactca
    11941 tcgaagaaaa tcccgaagtt aaatttcata ttgtagaaac gggtgcttat gaactgcaaa
    12001 aaaaaactgt ttctaaaaga agtcgatttt gcgattttat taacacccac tacactagat
    12061 gctactattg ctgatatcga cattctccta agagatcaac tctgccttta tatgagtcac
    12121 aaaacctttc aagagacgtt tgatagtaat cctaacatct ctatcaaagc attacatcgt
    12181 caaaacttag taacttttga taaaaccttt atgattaatc atcagcttac caccttattt
    12241 gaagaagcaa atagtcttcc tgtagtcaaa tgttattctg cctcgtggga ttttttatta
    12301 aattgcacgc gctattcctc ttacctaaca atcctaccaa gacctattac tcattttgct
    12361 catatagaca gtttagtgga ggtccaactg accgaacatc caaaatggga agttgttcta
    12421 gcctctctca agcacaataa aacaagccat ttaaaacatt atatcaagca caccatctta
    12481 gattatttca cgaaccagcg cttctaattg cttgactcag accttaaaaa aacgcctgaa
    12541 ggaaataatc ccaggcgttt catgtagtta tttcctaaaa tacaaatagg taaatgatgg
    12601 caatacctgt gaccaccaag acacaaggaa tagtataagc cacaatttga ttgaatttta
    12661 gtttgaagtt tgagaggtaa gataaggccc aaaaaggaac tatcaagttt gttgtggcat
    12721 ctcctaattg ataagcctgc aaaatcttac ctaggtcatt accaacttcg atagttgcag
    12781 ggacgatata gggagcttca atcacaaatt ttgagcctcc tgatggtacc gcaatattca
    12841 gcaaagccga gtaaagataa gcaaagaccg gccatgttgt cccatttgaa atagcgacaa
    12901 agaaatggga aatctctagt cctagacctg tactttgaat gattccaaaa ataccagcgt
    12961 aaaatggaaa ctgaagcacc aagccccaag atgacatgac cccatctttg aatagggaac
    13021 cataatattc tggtccttgt tgaccacaaa gaagcaaccc taagcctaaa aataaaaagt
    13081 taaaactatt gagatctaga ccagacaagc ccaccaccga aaaatgataa aggctatagc
    13141 taacaatggc cccaccaaca agatacatca ctaagcgaga tgcgttcatc ttctcagcag
    13201 gtgtgtttct tgcaataaca acatgtgaag cggtatcaag actatggtga tagatctcat
    13261 catcaagttc catgatttta gtttcatctt ttgggtgcgc caataaagca aagcaaagcg
    13321 gtaccagcat acacaccact aaaagactga taaatggaag attcaaaact gattctgtca
    13381 gaggaacact ttcaggaaca acctgtttat aagcatctgc gacactattt cgcaaataat
    13441 ctggagtagc cgaataaagc accgcagcac cagataaacc agaagtagct ggtaaaaagg
    13501 taaaaaataa agtagcaaca aacaaaggtg tatgcacctt aatccctttt tgcctagcct
    13561 gaacaagcaa ctctttccca aacacaatgg caaccatcat accaagaccc cagtgtaaaa
    13621 agccaaagat agagcctact acaatagaaa aaataaaaat ctgagtcctg gtttgaggca
    13681 gtttggcaag ggacttaaac attttatgag caggtggaga actcgctaca gcattccctg
    13741 tcgcaagtaa aatagtcatc tgcatggcaa aggacaacag cccccaaaaa ccatttaccc
    13801 agccatagat aatcccgccc gtcttttccg taccaataaa gggactatcc gtcatcaaca
    13861 cagacatagt aacgactaaa aaggttaaaa taaaacagat aaaaagcgat tctggcatcc
    13921 atttcataaa gccatcaata tagcgatcca taaacctttt tttggttttg atgttattca
    13981 tgttgtcaat tcctttcaca ttgtccacaa gcacttttgt tcttttgatc agtaacctat
    14041 caataatatt aataagcgtt tctttagttc atttagttat caataagttt aaacccacaa
    14101 aaaacacttt tgttcccttt ttattatgac aacgttttca tagacaaaca actatgattt
    14161 ttttattgct tccataaccc ttatttatag caaaaagaat gacgcttcac tcatcaacaa
    14221 tatctttgtt atatttaaat aattaaataa ttatgataaa aaattaaaaa ataatttact
    14281 ttttagtttg tttgatataa tatattagta ttaaaagaaa ggtttttcat gatatgaaac
    14341 gatgtaataa atatctcttc acttcactac tagcagcttc gatgctgttt agttcgtata
    14401 aatcagtaca tgcccatgat aacattgatg aggaaggtaa agtgcacctt tactggcagg
    14461 gaaattacta tgttgataac tatgtcgact atactaaaaa attggtcgat aacgataaaa
    14521 atattgaatg gactgtaacc tttaattcaa ctaaagaaca atgggtttac cctgatttct
    14581 cagtgtttct tcctaagggt gtaaaagctc ctaaggagat aacttatgag catcattatg
    14641 ggaacggtac agttcattct gaaacacgca gtaatacaca atggcattat aattgggaaa
    14701 accaacaaac aaattttaat caagaatttg ataaattccc tggttatact ggctggagta
    14761 cttctctaga taaattttac aaactaaaaa acgacggaaa attttctcac gttttagtag
    14821 acacctatgg ccgtcaatca cacacttatt tttctcataa aatggtttgg aagtttaaaa
    14881 ctgagcttga agataattac aaagataaat ggaataaatt accgtttata gcaggtatta
    14941 aacaaaacaa cccattagca gcatcattcc caagttataa aggggagttc ggcgagtaaa
    15001 tgaagctgcc aatccatcat cttttgcata attacagtca gagtctgaga caacatgatt
    15061 gctcagactc tttttatttc ttttattata cttaaagtaa ccgaaggagc tcttctgtac
    15121 gatatcccca ccgtacccca aaaaactggt gggcaaagtc caccagtttc tattacaatc
    15181 tcttatttaa ctatcacttg cttttcttag cacttactcg cgaatacata aacactaaaa
    15241 taatagctat aaccaccccg aaagcagcac acactacttc tgcccacatt cttgatttat
    15301 ccacgagttt cattgctttt ttagcctgtt gatacttttt ataatgatat gcaattctat
    15361 gacctctgac caatagacgc ttggtgttaa caccatatgg tgtgcaggta accagagtag
    15421 cataatcttt ccccattact ccagaaagtg atgtggcttg atctggttca acaattagta
    15481 tctgatcaac tttataagcc aatactttat ttaacacacg aaagtaaaaa gtatctccct
    15541 ttttcactaa attcaaatta gtaaacattt ctgccgatgg aaggcctcta tgagcagaaa
    15601 taaccgtgtg agtcccgtcg ccaccaactg gtaaggcact tccaaataag tgacctgctc
    15661 ccttagttaa cacctcgtct gtcgtatagt ggtatatggg taacgtcact ttaatagagg
    15721 gcacttcaac atatcccata atatcattgt tttcaatttg aagtaggctt tcgtagtttt
    15781 tatcatgaat gccatcccta aatgaaaaag catctggaac gggctgaatc ccaagcctag
    15841 cgttatacgc cttagccttt tgccacacct cctccatttc tgagggcttc ttttgaatca
    15901 cttgtttgtg ataagttgat aacaattgac gatcacgata ggcattccac tgactactta
    15961 gcgtagggta aagaaaaatg gctgttccca ataaaaataa taagagtatc cctagatttt
    16021 ttagtctttc tgtcatagca gttccttatc attaaaaatc gagaccgcat aaagacagtc
    16081 tcgattgatt tcgacttttg aaagcattaa gctttacgac gtttaacaat ataaatacca
    16141 attgcaccaa tcatagcagc cgaaccaata gctttaaaga ggtaagtacc aatgctacct
    16201 gtcgaaggta attcacctag cttggtgtta gggatgtcag tttctaataa tactgtacct
    16261 gaaccttcat tcgattttga gaaagttgtt ccatcagtta aagccttagt agattcaata
    16321 taagcctctt taacatcatt tcctgtaggt ctactatcta tagaatagaa tataccattt
    16381 tttaaccatc ctacttgctc tgaattatct gtcgccttat ttttatcaga tgtataagta
    16441 gtactttttg aattagcact tgtcttgact gtagcagtta cccaatttgc cgtaatttca
    16501 taagtttctg tattcaatga ataaccttta ggagctttta attccttaat tttatatttt
    16561 cctgaagata cttgtgttga aatagcatat ccatttttat tggttgtaac aatatcaatt
    16621 aatttattac tagtatcata aactccaaaa attgcaccaa taagtggggt cttactaaca
    16681 ctatcaactt ttctaaacgc tatttgataa gtataaacaa ttttagaatc ttctttggat
    16741 gtaataccat tccctttatc aggcttctta tctaaattat cgtatgtatt accttttgtt
    16801 ggattatttg aatagaagaa ttcagcttta ttaggattac cctcttcacc aacaatagct
    16861 ttattgttta caacagcttt ataacttata tttggtgata tagattctaa actatcataa
    16921 ataaaactta aattaaaacc gttattaacc tccttagcta ttccgatttt tgtattttct
    16981 accattactg aaccatcttc agtaatatta gccatcttac ctttccattc tactgtaaga
    17041 ctattaaagt taaaagtaag accttccgac atattatcag aaacatatac tgttttattg
    17101 actgcttctt tggtataact tggtaattca aatgtcagcg aataagacaa tacacttcct
    17161 aacgaggtag tctttttatt cacgtcatct attgtcccgg ttactttctt tgtaatagat
    17221 ggtaatgatg attttgcaac acttgtttgt ccatataaat aattagattt ggaatcaata
    17281 tttttagtaa ctaaatttcc ctcaccatta taagatgcag ctaataaaat aggattgtag
    17341 gtacggccat ctgtcgcacc tgttaataat gcaatataaa cagatgcacc tctcgcatta
    17401 taagttgctg ttccattaga aatactaacg ttttcagtac taaaaggctt tattttaccc
    17461 gtattaatac catttgcaat agtagtaatt tcttgtgatg taggtcctgt ttcagttaaa
    17521 gaaaccccct cagcatattt aaagttaata aaagaatcac cattagtgtt gtaaacacct
    17581 tctcctattt tataaagtgt tactgttggc ccaccttcaa tatttgttat ctttagttgt
    17641 gcagtatcat cttttgataa agctgatact cttgtcattc caagccctac taccgctaag
    17701 atagctaaac aagctagcat tagttttttt gctgttatta atatcttctc tctcactgtt
    17761 tctctcctgt ttgtcaataa atatgatcat taatttaata ttgctttttc ctgtgttggc
    17821 gtctataaaa taataatgct acagttgctg tcatgctacc aactataatg aaaatttgac
    17881 ttcctcttcc cccagacgat ggcaactgat aaatcttata atttttaatc atgtaagagc
    17941 catcttttga cttcaattca ccttcaatcg ggtgttttac ttttatatca ccgttgttag
    18001 caacggcaac ttcccatgga ttttctggaa gagtgtatcc aagttttgcc ttcgtctcat
    18061 acagataata ggttttgcct ttttgaaggt acttaaagtt gagttggcca tttgaacctg
    18121 ttgttccctt ttcccagacg atcttcttgt cctctttacg gagttcaaac tcaacacctg
    18181 caagtttttt ctggttgttg tcagcatcta ctttggtaaa cgtgattggt actgttttga
    18241 cctgaatcac tgggtgctta taaggtaatt tctgttcacg accatctgcc atataattaa
    18301 ccgaagcatc tgaattagaa ggcaaaccac cttttccaga actagtttgg ttggttccat
    18361 aatcagtatc ggaatctccc atttcgctat atcttccttc gttatcctta tacttctcat
    18421 aggcttcatc tgaagctttc acattaaaag aaagcgtata ggtatattca tcatcaacct
    18481 tataatcaga cttaaaggtt aaagtaactt taccttttgg ttgactagta gttttcgggg
    18541 taaatacaac tttatcaatg atatctttac cagcttcttg aacttggtct ttttggtata
    18601 aaatctctgt ttcatcatta accttcgatt ttctagtaac aagtacatca ggttgtttat
    18661 catagtagtc aacatactga cttaaactat ccgaaattcc tagctgagat aacttactat
    18721 cctcaacaat tttattcaaa gttttttcta attctgctgt gtccgtaata ccgtagtaat
    18781 gctcctcacc tgacaagtat tttaggacaa caggactgga acttgccgta tcactattaa
    18841 tatctttaga aacgcccaat gaatatattg acaagttagg atatctagcc ttaaactcat
    18901 ctattgcaag tttgcttcct tcttgtgatc gtgtaacatt attacgatca tttgaactac
    18961 catttcctga gcgatagcca tcttctccaa aataaaacgt gggaactcca tcacttatga
    19021 atatcattat ttttcttcgg ccatcatctt ttacttcatt tagaatctct ttagctttta
    19081 ataaagcagc atgataattg gtaccattgt tatgcaatgc tgtcaaagta ttaggatcta
    19141 ataaagaatt agtagaccat cccttaagaa gttcagcatc tctactatta tttaaattag
    19201 gctgataaaa tccaccacgt ggggattgat caggatacca ttttcctgca tggtaatcag
    19261 cactgccttg aaagccaata actgataatt tattttctgg attaatatta acaaatctct
    19321 gcaacaatcc atttacgcct agaagagaat tttttaccgc atcatctctt ctaataccat
    19381 cagatacaga tacaatacct ctatatctat aatgaatttg acctctgtta aaagactcac
    19441 cttgatagct agaatagtca aaagttccat gataaaccca ttgactatag taatcatccc
    19501 atctctgagc atagtatcta tatctttgaa ccgatcctat cccttcctgc atactccctg
    19561 acttatccac aacaacaaga atatctaggg gatttttctt tcctgtcata tccagataga
    19621 gacaatagag atcagaggtg tcatgttcgt cttctttatc gtcgatggtg gtatcaggat
    19681 tattttgatt atctcctaaa tagtcaatcc gcttatggtg ctccaattca ccttcgaatt
    19741 tctcaactgg ggcagacctc ttcattctag ttgatctggg agttaaggag cgaaaagaac
    19801 gtggctgaat tagtgctggg gctgctccta ttggttttaa cccaagtggc cttgttgaac
    19861 gaatgtaaat gttaattgta ttgttatggc ctttattcat gactaaaggc tcaacagtgt
    19921 attctccaaa taaaatgtct cgtgtttgtg gggtgctatc cttagctgat tggtagtccg
    19981 tttttaaaac ttcgtattgt ttggaaataa aatccaagag ataaaactga tcgtcccaag
    20041 tgtagagatt atcaatcgtt ttaacgattt caaaatcttt agaatcaagc gaactttcaa
    20101 ttgaggataa ctttggtttt aagatattta ctgtgattgg cttgctgtaa gggggcctat
    20161 ctttctggct gagcccaaca gctccatcaa taactaattc tccataagaa tctaatgaga
    20221 tcgtttgttc ttcttttaga cgagttgtgc taactattat gacctgtttc ccaagcctgc
    20281 cagtaaaaac aaggttctta actttaccat ctgcgtcttg tttaatagta ggtgttattg
    20341 tttgaacagt atcattagga tttacgatac ctactcttac attcgggtcg tttgcttcgg
    20401 ttgaagcacc ttctaaagat aagccattct taaaagttaa ggttgttgtg atatcgtttc
    20461 tttgattggt agaagactgg attctaacta ttttggtatc aacgattgat agcccttgct
    20521 ttctcaattc taatgccata gtaacgatag cttgagttac gctacgttga ctattatctc
    20581 cttgggattc tgtatctaaa gaagcatcaa tcgtggcatt atgttcaaaa cctgattctc
    20641 ttttaagagc tacctttaga ctactatttt ctgactctaa tttttgtttc gttgcaacta
    20701 cctgagttcc ctgagtttct gtttgagtaa caatctcttg ggggatcact ttggtctgtg
    20761 tagaaatcat ctgcaagcct agtcgcctta taggtaaaac taactgcgaa aaaataaggc
    20821 ctacggtaac catcagtcta attagtttat atttcttttt tctgtttatc actataacta
    20881 actctctctt caatctactg tacattaaac gttacaaaaa taaagtttct aatatatcta
    20941 gtttatcata actacattta tatatctagt ttatcataac tacatttata tatctagttt
    21001 atcataacta catttacttt agattattgt aagctcattt tttctccata tttcttatat
    21061 gaaaagctca tttttgagaa aaatgtttat ttggagctgt ttccaagcac tctgaaattt
    21121 attttctagt cttttaattt ggtttctatt tttagcttag atagaaatcg agtaggagct
    21181 aatttctagc ccctctcaca ccaccgtgcg tgccgttcgg cacacggcgg ttcaattaac
    21241 ttttaacgca tgtcgttcta agtagtcatc caagcaagaa aacagtcccc gttctgcgag
    21301 gactgttttt gatatagctt gttttagaac tgacttttga gctactaatt gacaatggtc
    21361 gctccatctt gattgtggac gacttttcca cccctctttg cgtattcctt tcttattttg
    21421 gtgtctgagg gacatcttat attagtgaac tttcctctag tcaatacgtg accgcaccca
    21481 gttctatcag accactagtt ttacagacac aagtgaagta ggtatacttc ggttaattgt
    21541 ttagcccttc gctctacttc cattacagaa gtttcatcgc tactatggca tcggctgact
    21601 tctcatcatt cgttattact acgtctagaa cgctcatgag acctcaaagg ataaggtgta
    21661 tatctttcct cgtttaccct catatttacg cctataggtt actactactt ttttggactt
    21721 tagactcatc cgctatatac gccttgatat cacgtttctg tttgtagagc cacgatttca
    21781 ctcccccttc ctctccccac tactcacgat agtcagactt gggcgtcgct attggattca
    21841 ccggtagcgg gtgtccacgg aggactctca cctccgatgt acaacatgcc tgtcgcactt
    21901 aaaaatcgag accgcataaa gacagtctcg attgatttcg acttttgaaa gcgttaagct
    21961 ttacgacgtt taacaataac ttgatttctt gtaagtctat tatacataga atacaccatt
    22021 ttttagccat cctacttgct ctgaattatc tgtcacctta ttattatcag atgtataagt
    22081 agtacctttt gaattaacac ttatcttgac tgtagcagtt atccgctatt cagcatattt
    22141 gcgcattatt tcttatggaa cacttttacg tcagactttt ttattgcttt gtttgttttt
    22201 taaaaggcta aaaatagaaa gtactgacaa aataaggatt ccaagaaagg ccaaaacatt
    22261 ctcaatatct cctgttgcag gaaggatagg tgttatattt tttgtaggct tttcccgatt
    22321 ctcttccact ttgggctcat tattgtcaaa atggaacact aacttcggac gcgtatcttc
    22381 aacaacagtc gccgtttcac tgaaaccact catgcctgtt tgagt
//
LOCUS       DAXMQE010000029        21839 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.029, whole genome shotgun sequence.
ACCESSION   DAXMQE010000029 DAXMQE010000000
VERSION     DAXMQE010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21839)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21839)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21839
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.029"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            complement(521..907)
                     /gene="rplQ"
                     /locus_tag="ACF4ZO_001329"
     CDS             complement(521..907)
                     /gene="rplQ"
                     /locus_tag="ACF4ZO_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HFD5486858.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAYVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            complement(922..1860)
                     /locus_tag="ACF4ZO_001330"
     CDS             complement(922..1860)
                     /locus_tag="ACF4ZO_001330"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HFD5486859.1"
                     /translation="MIEFEKPIITKIDENKDYGRFVIEPLERGYGTTLGNSLRRVLLS
                     SLPGAAVTSIKIDGVLHEFDTIPGVREDVMQIILNVKGLAVKSYVEDEKIIELEVEGP
                     AEVTAGDILTDSDIELVNPDHYLFTIAEGHSLRATMTVAKKRGYVPAEGNKKDDAPVG
                     TLAVDSIYTPVKKVNYQVEPARVGSNDGFDKLTIEIMTNGTIIPEDALGLSARVLIEH
                     LNLFTDLTEVAKATEVMKETEKVNDEKVLDRTIEELDLSVRSYNCLKRAGINTVFDLT
                     EKSEPEMMKVRNLGRKSLEEVKVKLADLGLGLKNDK"
     gene            complement(1906..2289)
                     /gene="rpsK"
                     /locus_tag="ACF4ZO_001331"
     CDS             complement(1906..2289)
                     /gene="rpsK"
                     /locus_tag="ACF4ZO_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HFD5486860.1"
                     /translation="MAKPTRKRRVKKNIESGVAHIHATFNNTIVMITDVHGNALAWSS
                     AGALGFKGSRKSTPFAAQMAAEAAAKSAQEHGLKTVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            complement(2307..2672)
                     /gene="rpsM"
                     /locus_tag="ACF4ZO_001332"
     CDS             complement(2307..2672)
                     /gene="rpsM"
                     /locus_tag="ACF4ZO_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HFD5486861.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDIR
                     VKDLTSDQEDAIRREVDAIKVEGDLRREVNMNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            complement(2690..2806)
                     /gene="rpmJ"
                     /locus_tag="ACF4ZO_001333"
     CDS             complement(2690..2806)
                     /gene="rpmJ"
                     /locus_tag="ACF4ZO_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HFD5486862.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPTNPKHKQRQG"
     gene            complement(2832..3050)
                     /gene="infA"
                     /locus_tag="ACF4ZO_001334"
     CDS             complement(2832..3050)
                     /gene="infA"
                     /locus_tag="ACF4ZO_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HFD5486863.1"
                     /translation="MAKEDVIEIEGKVVETMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILVGDRVTVEMSPYDLTRGRITYRFK"
     gene            complement(3168..3806)
                     /locus_tag="ACF4ZO_001335"
     CDS             complement(3168..3806)
                     /locus_tag="ACF4ZO_001335"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HFD5486864.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEEFGVAHISTGDMFRAAMANQTE
                     MGRLAKSYIDKGELVPDEVTNGIVKERLAEDDIAEKGFLLDGYPRTIEQAHALDATLE
                     ELGLRLDGVINIKVDPSCLVERLSGRIINRKTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNMAQEEPILEHYRKLDLVTDIEGNQEITDVFADVEKALLELK"
     gene            complement(3956..5260)
                     /gene="secY"
                     /locus_tag="ACF4ZO_001336"
     CDS             complement(3956..5260)
                     /gene="secY"
                     /locus_tag="ACF4ZO_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015631723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HFD5486865.1"
                     /translation="MFLKILKDALKIKTVRNKIFFTIFIILVFRIGTHITVPGVNAKS
                     LEQLSELPFLNMLNLVSGNAMRNFSVFSMGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYISLVLAFAQSIGITAGFNTLSNVALVKTPDIKTYLLIGALLTTG
                     SVIVTWLGEQITDKGFGNGVSMIIFAGIISSIPSAIATIREDYFVNVKASDLHSSYLI
                     VGILIIAVLAIVFFTTYVQQAEYKIPIQYTKLMQGAPTSSYLPLKVNPAGVIPVIFAS
                     SITTIPSTIIPFVQNGRDLPWLNRLQEIFNYQTPVGMIVYALLIILFSFFYTFVQVNP
                     EKTAENLQKNSSYIPSVRPGRETEQFMSALLKKLATVGAIFLAFISLAPIAAQQALNL
                     SSSIALGGTSLLILISTGIEGMKQLEGYLLKRKYVGFMNTAE"
     gene            complement(5277..5717)
                     /gene="rplO"
                     /locus_tag="ACF4ZO_001337"
     CDS             complement(5277..5717)
                     /gene="rplO"
                     /locus_tag="ACF4ZO_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HFD5486866.1"
                     /translation="MKLHELKAAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRIPKRGFTNINTKEYALVNLDQLNVFDDGTEVTPAILKDAGIV
                     RAEKSGVKVLGNGELTKKLTVKAAKFSKSAEAAIIAKGGSIEVI"
     gene            complement(5932..6114)
                     /gene="rpmD"
                     /locus_tag="ACF4ZO_001338"
     CDS             complement(5932..6114)
                     /gene="rpmD"
                     /locus_tag="ACF4ZO_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HFD5486867.1"
                     /translation="MAQIKITLTKSPIGRKPEQRKTVVALGLGKLNSSVVKEDNAAIR
                     GMVTAISHLVTVEDVK"
     gene            complement(6129..6623)
                     /gene="rpsE"
                     /locus_tag="ACF4ZO_001339"
     CDS             complement(6129..6623)
                     /gene="rpsE"
                     /locus_tag="ACF4ZO_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HFD5486868.1"
                     /translation="MAFKDNAVELEERVVAINRVTKVVKGGRRLRFAALVVVGDGNGR
                     VGFGTGKAQEVPEAIRKAVEAAKKNMIEVPMVGTTIPHEVYTNFGGAKVLLKPAVEGS
                     GVAAGGAVRAVIELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEVAALRGISV
                     SDLA"
     gene            complement(6642..6998)
                     /gene="rplR"
                     /locus_tag="ACF4ZO_001340"
     CDS             complement(6642..6998)
                     /gene="rplR"
                     /locus_tag="ACF4ZO_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HFD5486869.1"
                     /translation="MISKPDKNKIRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKDVSKGTKTEQAVVVGKLVAERAVAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            complement(7103..7639)
                     /gene="rplF"
                     /locus_tag="ACF4ZO_001341"
     CDS             complement(7103..7639)
                     /gene="rplF"
                     /locus_tag="ACF4ZO_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HFD5486870.1"
                     /translation="MSRIGNKVITMPAGVELTNNNNVITVKGPKGELTREFNKNIEIK
                     VEGTEITVVRPNDSKEMKTIHGTTRANLNNMVVGVSEGFKKDLEMKGVGYRAQLQGTK
                     LVLSVGKSHQDEVEAPEGITFTVANPTSISVEGINKEVVGQTAAYIRSLRSPEPYKGK
                     GIRYVGEYVRLKEGKTGK"
     gene            complement(7841..8239)
                     /gene="rpsH"
                     /locus_tag="ACF4ZO_001342"
     CDS             complement(7841..8239)
                     /gene="rpsH"
                     /locus_tag="ACF4ZO_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HFD5486871.1"
                     /translation="MVMTDPIADFLTRIRNANQVKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEVIEDDKQGIIRVFLKYGKNGERVITNLKRISKPGLRVYAKRDDMPKVLNGLG
                     IAIISTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            complement(8390..8575)
                     /locus_tag="ACF4ZO_001343"
     CDS             complement(8390..8575)
                     /locus_tag="ACF4ZO_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HFD5486872.1"
                     /translation="MAKKSMIAKNKRPAKHSTQAYTRCEKCGRPHSVYRKFKLCRVCF
                     RELAYKGQIPGVVKASW"
     gene            complement(8591..9133)
                     /gene="rplE"
                     /locus_tag="ACF4ZO_001344"
     CDS             complement(8591..9133)
                     /gene="rplE"
                     /locus_tag="ACF4ZO_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HFD5486873.1"
                     /translation="MANRLKEKYTNEVIPALTEKFNYTSVMAVPKVEKIVLNMGVGDA
                     VSNAKNLEKAAAELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEISFDDVDKVRGLDIVIVTT
                     ANTDEESRELLKGLGMPFAK"
     gene            complement(9157..9462)
                     /gene="rplX"
                     /locus_tag="ACF4ZO_001345"
     CDS             complement(9157..9462)
                     /gene="rplX"
                     /locus_tag="ACF4ZO_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HFD5486874.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLKALPKVNKVIVEGVGMIKKH
                     QKPNTENPQGAIVEKEAPIHVSNVQVLDKNGVAGRVGYKVVDGKKVRYSKKSGEVLD"
     gene            complement(9541..9909)
                     /gene="rplN"
                     /locus_tag="ACF4ZO_001346"
     CDS             complement(9541..9909)
                     /gene="rplN"
                     /locus_tag="ACF4ZO_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HFD5486875.1"
                     /translation="MIQQETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKTGARRPDGSYIKFDDNAAVIIRDDKTPRGTRIFGPV
                     ARELREGGYMKIVSLAPEVL"
     gene            complement(9934..10194)
                     /gene="rpsQ"
                     /locus_tag="ACF4ZO_001347"
     CDS             complement(9934..10194)
                     /gene="rpsQ"
                     /locus_tag="ACF4ZO_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HFD5486876.1"
                     /translation="MERNQRKTLYGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            complement(10220..10426)
                     /gene="rpmC"
                     /locus_tag="ACF4ZO_001348"
     CDS             complement(10220..10426)
                     /gene="rpmC"
                     /locus_tag="ACF4ZO_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HFD5486877.1"
                     /translation="MKLQEIKDFVKELRGLSQEELAKKENELKKELFDLRFQAAAGQL
                     EKTARLDEVKKQIARVKTVQSEMK"
     gene            complement(10436..10849)
                     /gene="rplP"
                     /locus_tag="ACF4ZO_001349"
     CDS             complement(10436..10849)
                     /gene="rplP"
                     /locus_tag="ACF4ZO_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HFD5486878.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVSFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            complement(10853..11506)
                     /gene="rpsC"
                     /locus_tag="ACF4ZO_001350"
     CDS             complement(10853..11506)
                     /gene="rpsC"
                     /locus_tag="ACF4ZO_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HFD5486879.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFINK
                     ELADASVSTIEIERAVNKVIVSLHTAKPGMVIGKGGANVDALRGQLNKLTGKQVHINI
                     IEIKQPDLDAHLVGENIARQLEQRVAFRRAQKQAIQRTMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            complement(11519..11863)
                     /gene="rplV"
                     /locus_tag="ACF4ZO_001351"
     CDS             complement(11519..11863)
                     /gene="rplV"
                     /locus_tag="ACF4ZO_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HFD5486880.1"
                     /translation="MAEITSAKAMARTVRVSPRKTRLVLDLIRGKKVADAIAILKFTP
                     NKAARVIEKTLNSAIANAENNFGLEKANLVVSETFANEGPTMKRFRPRAKGSASPINK
                     RTTHVTVVVSEK"
     gene            complement(11879..12157)
                     /gene="rpsS"
                     /locus_tag="ACF4ZO_001352"
     CDS             complement(11879..12157)
                     /gene="rpsS"
                     /locus_tag="ACF4ZO_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HFD5486881.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRR"
     gene            complement(12296..13129)
                     /gene="rplB"
                     /locus_tag="ACF4ZO_001353"
     CDS             complement(12296..13129)
                     /gene="rplB"
                     /locus_tag="ACF4ZO_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HFD5486882.1"
                     /translation="MGIKVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVSLKSKAGRN
                     NNGRITVRHQGGGHKRHYRLIDFKRNKDGVEAVVKTIEYDPNRTANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPDADIKVGNALPLANIPVGTVVHNIELKPGKGGELVRAAGA
                     SAQVLGQEGKYVLVRLQSGEVRMILGTCRATIGTVGNEQQSLVNIGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            complement(13147..13443)
                     /locus_tag="ACF4ZO_001354"
     CDS             complement(13147..13443)
                     /locus_tag="ACF4ZO_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HFD5486883.1"
                     /translation="MNLYDVIKKPVITEKSMIALEAGKYTFEVDTRAHKLLIKQAVEA
                     AFDGVKVASVNTVNVKPKAKRVGRYTGFTSKTKKAIITLTADSKAIELFAAEAE"
     gene            complement(13443..14066)
                     /gene="rplD"
                     /locus_tag="ACF4ZO_001355"
     CDS             complement(13443..14066)
                     /gene="rplD"
                     /locus_tag="ACF4ZO_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HFD5486884.1"
                     /translation="MANVKLFDQTGKEVSSVELNDAIFGIEPNESVVFDVVISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSAKVAEDKFVAVEGLSFAAPKTAEFAKVLSALSIDTKVLVLVEEGN
                     EFAALSARNLPNVTVATAATASVLDIVNADKLLVTKEAISTIEEVLA"
     gene            complement(14090..14716)
                     /gene="rplC"
                     /locus_tag="ACF4ZO_001356"
     CDS             complement(14090..14716)
                     /gene="rplC"
                     /locus_tag="ACF4ZO_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HFD5486885.1"
                     /translation="MTKGILGKKVGMTQIFTESGEFIPVTVIEATPNVVLQVKTVETD
                     GYEAVQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNIEGLEVGAELSVEQFEA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRLAG
                     RMGGNRVTVQNLEIVQVILEKNVILVKGNVPGAKKSLITIKSAVKAAK"
     gene            complement(14964..15272)
                     /gene="rpsJ"
                     /locus_tag="ACF4ZO_001357"
     CDS             complement(14964..15272)
                     /gene="rpsJ"
                     /locus_tag="ACF4ZO_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HFD5486886.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAEKIVETATRTGATVAGPVPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLVDIINPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            complement(15471..16760)
                     /locus_tag="ACF4ZO_001358"
     CDS             complement(15471..16760)
                     /locus_tag="ACF4ZO_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HFD5486887.1"
                     /translation="MIYNRRKIFSLALPSMIENILQMLMGMVDNYLVAQIGLVAVSGV
                     SIANNIISIYQSLFIALGAAVSSLIARSIGENNQNKQLNYMAGVLQVTLLLSVGLGLL
                     SVVGHHQVLEWLGAEASVTLVGGQYLSIVGGMIVSLGLLTSLGAIVRAQGYPKIPMQV
                     SLLINVLNAIFSALSIYVWGFGLLGVAWATVLSRLVGVFLLCQFIPIKQVAKRLMRPL
                     DKIIFDLSLPAAGERLMMRAGDVLIIGIVVRFGTTALAGNAIGETLTQFNYMPGLAMA
                     TATIILVARQLGGGKVTEIRYIIREAFILSTLMMLVMGALTYLLGPSLLPLFTQNTDA
                     QRSAMVVLLFSLLGAPATAGTLVYTAVWQGLGKAKLPFYATTIGMWVIRIGLGYVIGV
                     VWQYGLIGVWMATVLDNTSRWFILSKQFKKYQEITFH"
     gene            complement(17148..18164)
                     /gene="adhP"
                     /locus_tag="ACF4ZO_001359"
     CDS             complement(17148..18164)
                     /gene="adhP"
                     /locus_tag="ACF4ZO_001359"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HFD5486888.1"
                     /translation="MKAVVVNQASTGVEVVEHDLPNVGHGEALVKVEYCGVCHTDLHV
                     AHGDFGQVPGRILGHEGIGIVEEIGEGVTSLKVGDRVSIAWFFEGCGHCEYCTTGRET
                     LCRSVKNAGYSVDGGMSEYAVVTADYAVKVPEGLDPAQASSITCAGVTTYKAIKEAGA
                     APGQWIVIFGAGGLGNLAVQYAKKVFNAHVVAVDINNDKLELAKEVGADILVNGKEIE
                     DVPGYIQEKIGGAHGVVVTAVSKVAFNQAIDSVRAGGTVVAVGLPSEYMELSIVKTVL
                     DGIKVVGSLVGTRKDLEEAFAFGAEGLVAPVVEKVPVDTAPEVFDEMERGLIQGRKVL
                     DFIS"
     gene            complement(18416..21058)
                     /gene="adhE"
                     /locus_tag="ACF4ZO_001360"
                     /gene_synonym="adhC"
     CDS             complement(18416..21058)
                     /gene="adhE"
                     /locus_tag="ACF4ZO_001360"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004022 - alcohol dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006066 - alcohol metabolic process
                     [Evidence IEA];
                     GO_process: GO:0015976 - carbon utilization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HFD5486889.1"
                     /translation="MTEGHNTVETTSVSVTIDALVQKGLAALEEMRKLDQEQVDYIVA
                     KASVAALDAHGELAKHAYEETGRGVFEDKATKNLFACEHVVNNMRHQKTVGIIEEDDV
                     TGLTLIAEPVGVICGITPTTNPTSTAIFKSLISLKTRNPIIFAFHPSAQESSAHAARI
                     VRDAAIAAGAPENCVQWVETPSLEATNALMNHDGIATILATGGNAMVKAAYSCGKPAL
                     GVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDDFVAEFKS
                     YHTYFVNKKEKALLEEFCFGAKANSKNCAGAKLNPNIVGKPATWIAAQAGFTVPEGTN
                     ILAAECKEVSENEPLTREKLSPVIAVLKSESREDGVEKARQMVEFNGLGHSAAIHTAD
                     AELAKEFGTRIRAIRVIWNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNAVGDNVSAIN
                     LLNIKKVGRRRNNMQWFKVPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGFLDR
                     IIEQLDLRRNKVVYQIFAEVEPDPDITTVMKGTELMRTFKPDTIIALGGGSPMDAAKV
                     MWLFYEQPEVDFHDLVQKFMDIRKRAFKFPELGKKTKFVAIPTTSGTGSEVTPFAVIS
                     DKANNRKYPIADYSLTPTVAIVDPALVLTVPGFIAADTGMDVLTHATEAYVSQMANDF
                     TDGLALQAIKIVFDNLEKSVKTADFEAREKMHNASTMAGMAFANAFLGISHSMAHKIG
                     AQFHTVHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIAKLLGLPASTP
                     EEAVESYAKAVYDLGCRVGIQMNFKAQGIDENEWKEHSRELAYLAYEDQCSPANPRLP
                     MVDHMQEIIEDAYYGYAERPGRRK"
     gene            complement(21367..>21839)
                     /locus_tag="ACF4ZO_001361"
     CDS             complement(21367..>21839)
                     /locus_tag="ACF4ZO_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HFD5486890.1"
                     /translation="ALRSSAAFSKIMPQAQLDAAVSRNFKEAFDLFNNQIKSKSLSKT
                     VVLAVGVNSLDNYSQAVQSFIEALPKGHRLVLVSPYNAKNASQVAEARDYGLKLSKKY
                     KYVTIADWYKVAVEHPDIWYGSDGVHYSEDSQGAELYASTIQTAVEKSAKKPAK"
BASE COUNT         6313 a         4622 c         3910 g         6994 t
ORIGIN      
        1 tttgttggaa acggcttaaa gtgacagatt ttaaaagtaa aaaagatatt ttcacctcca
       61 aattaaaaga ggattttaaa atacttatta ataaaatatt gaataggaga taaaactaac
      121 aatatagttt gagcatctgt ttgcgatgca agtttttttc ggacatttaa atgagggggt
      181 tacaccgttt atttgcccat gagaggtctt taaacacctg cataaggttt tcttattcta
      241 atgaccttat tgtctctgag aaaactttat aaacgcatca gaagaggctt ctgtgttatt
      301 gttttgctca gcttaaaagc ggggggtcac ctcataatac aacaaaacgc ctgcttataa
      361 aaagtttcta tagcttagat acctttcata aacaagcgtt acatattaac aatatgatga
      421 gtgttcccgc taggaaaaat cctagcggta gaccagagct agactaagaa taatctctcg
      481 attactccat catcataaca ctcaacaaaa ttgataaaaa ttaaactaat tcaataattg
      541 ccattggagc agcatctcca cggcgtggtt ctgttttaag aatacgagtg tatccaccgt
      601 tacgttctgc ataacgaggt gcaatttctg agaaaagttt ttgaagagct gtcgttgatg
      661 tgtatttatc ggtagcttca tcataatttt ctgatgcgat ttcgttacga acgtatgcag
      721 ctgcttggcg acgagcatga agatcaccac gtttaccaag agtaatcatt ttttcaactg
      781 ttttacggat ttcttttgca cgtgcttctg tcgttacaat tgattcgttg atcaaaagat
      841 ctgtcgtcaa atcacgaagc attgctttac gttgtgagct agtgcgtcct agtttacggt
      901 aagccatttt gtcctcctat attatttatc gttttttagt ccgagaccta agtcagcaag
      961 tttaacctta acttcttcaa ggctcttacg tccaagatta cggactttca tcatttcagg
     1021 ctcagatttt tctgttaagt cgaatacagt gttaatgcct gcacgtttta aacagttata
     1081 tgagcgtacg gataaatcaa gctcctctat ggtgcggtca agtacctttt catcgttcac
     1141 tttttcagtt tctttcatta cttcggtagc ttttgcaacc tctgttaaat cagtaaacag
     1201 gtttaagtgt tcgatcaaaa ctcgagcaga tagacctaaa gcatcttcag gaataattgt
     1261 tccgtttgtc atgatttcaa tcgttaattt atcaaagcca tcattgctac ctacacgggc
     1321 aggctcaact tgataattaa cttttttaac tggcgtatag attgaatcta ctgccaatgt
     1381 acccacaggt gcatcatctt ttttgttgcc ttctgctggc acataaccac gttttttagc
     1441 aacagtcatt gttgcacgta gagaatgtcc ttcagcgatt gtaaaaagat aatgatccgg
     1501 gttaacaagc tcgatatcac tgtcagtaag aatatcacca gctgttacct ctgctggtcc
     1561 ttctacttca agttcgataa tcttttcgtc ttcgacgtat gatttcacag caagtccctt
     1621 aacattaagg ataatttgca tgacatcttc acgtacacct gggattgtat caaattcgtg
     1681 tagtactcca tcaattttaa ttgatgttac tgctgcacct ggaagtgaag acaagagtac
     1741 acgacgaaga gaattaccta gagttgttcc gtagccacgt tcaagtggtt cgatgacaaa
     1801 tctaccgtaa tctttatttt catcaatttt tgttattatt ggtttttcaa actcaatcat
     1861 tttttcaccc ctcgaaacga aacttgtgta ctatttgtta tatgattata cacgacgacg
     1921 ttttggagga cgagcaccat tatgtggcac aggggtcaca tcacgaattg cagttacttc
     1981 aagacctgca gctgctagag cacgaatagc tgattcacga cctgaaccag gaccttttac
     2041 agtcacttca acagttttta gtccgtgttc ttgtgcagat tttgcagcag cttctgcagc
     2101 catttgagca gcaaatggag tagatttacg agaacctttg aaaccaagag caccagctga
     2161 tgaccatgca agagcattac catgcacatc tgtaatcata acaatagtgt tattaaatgt
     2221 agcgtgaatg tgtgcaacac cagattcgat gttctttttc acacgacgtt tacgtgttgg
     2281 tttagccaat tgttttacct cctattttat tttttcttac ctgcaatcgc aacagctttc
     2341 cctttacgag tgcgagcatt gtttttagta ttttgtccac ggacaggaag tccacgacga
     2401 tgacggattc cacggtatga accgatttcc atcaaacgtt taatgttcat gtttacttca
     2461 cgtcgaaggt caccttcaac tttgattgca tccacttcac gacggatagc atcttcttga
     2521 tctgatgtca aatctttaac acggatatct tcagaaatac ctgcagctgc taagattttt
     2581 ttagatgttg caagaccaat tccgtaaaca taagtaagtg aaattactac gcgtttatca
     2641 tttggaatat caactccagc aatacgagcc attttttctc ctttctattt tatccttgac
     2701 gttgtttgtg ttttggattt gtcggacaaa ttaccataac acgaccatta cggcgaataa
     2761 ctttacagta ttcgcaaatt ggtttaaccg atggtcttac cttcatgttt taatccctcc
     2821 aattatttcg attatttaaa gcggtatgtg atgcgtccac gtgtcaagtc ataaggactc
     2881 atttctactg taacacggtc acctactaaa atacgaatgt aatttttgcg gatttttcct
     2941 gatacagttg ctagaatttg atgtccattt tccaattcaa cagtaaacat tgcatttggc
     3001 atcgtttcta ctactttgcc ttcaatttca atcacgtctt cttttgccac gcaaaagtac
     3061 cccctaaatt tcgatttgat gtcctctgag cacagaggta acaattataa gtcagactaa
     3121 actagtatat cattactaat ctacttatgc aagtagatta gtataattta tttgagttct
     3181 agcaacgctt tttcaacatc tgcaaaaacg tctgttattt cttgattacc ttcaatatct
     3241 gtaacaagat caagcttacg atagtgttca agaataggtt cttcttgagc catattgacg
     3301 tccaaacgac gtttaacagt ttcaggctta tcatcttcac gttgatagta atcttcttct
     3361 ttataatcta ctggtgggtt gaacacttta tggaacgttt caccagtttt acgattgata
     3421 atacgaccac tcaaacgctc tacaagacat gatggatcca ctttaatatt aataacacca
     3481 tctaagcgga gtcctagttc ttcaagtgtt gcatctaagg cgtgtgcttg ttcaatagta
     3541 cgtggatacc catcaagcaa aaaacctttt tctgcgatat catcctcagc taagcgctct
     3601 tttacaatcc cgtttgtgac ttcatcagga accaattcac ctttatcaat ataactttta
     3661 gctaaacgtc ccatttcggt ctgattagcc attgcggcgc ggaacatatc ccctgttgag
     3721 atgtgagcaa caccaaattc ttcaacaatc ttagctgctt gggtcccttt accagctccc
     3781 ggcaagccca tgattaaaag attcatcttt tcctcctctt ttaaaataaa tacatagtag
     3841 gaaattattt tccttggttt ttgttttcaa atggcaacaa gaaatcgttt gatgataacc
     3901 aagtcttatt gtcatttaaa aacaaaatag aaggttgaca atgtcaacct gtattctatt
     3961 ctgctgtatt cataaatccg acatattttc tctttagaag atacccctca agctgtttca
     4021 taccttcgat accagttgaa atcaaaatga gcaaactagt tccacctaaa gcaatactag
     4081 aagaaaggtt gagagcttgt tgtgctgcta ttggcgctaa agagataaat gctaagaaga
     4141 tagctcctac ggttgctaat ttttttagca atgcggacat aaattgttct gtctcacgtc
     4201 cagggcgaac acttggtata tatgaggaat tcttctgaag attttctgct gtcttctcag
     4261 gattaacttg tacaaaggta tagaagaatg agaacaatat aatcaacaag gcgtaaacta
     4321 tcattccgac tggagtttga taattaaaaa tttcttgcaa acggtttaac cacggtaaat
     4381 ctctaccatt ttgaacaaaa ggaataatcg tacttgggat agttgtaatc gagctagcaa
     4441 agataacggg aataacgccg gctggattta cttttaatgg aagatatgaa cttgtaggtg
     4501 caccttgcat tagctttgtg tattggattg gaattttata ttccgcttgt tggacatatg
     4561 ttgtaaagaa aacaatagca agaacagcta tgattaaaat cccaacaatg agataagacg
     4621 agtgtaaatc acttgcctta acatttacaa aatagtcttc acgaattgtt gcaattgcac
     4681 ttggaataga cgaaataata cccgcaaaga taatcattga tacgccatta ccaaatcctt
     4741 tatctgtgat ttgttctcca agccaggtaa caataacgct acctgttgtc agtaatgccc
     4801 cgatcagcaa atatgttttg atgtctggtg tcttaacaag tgcaacgttc gacaaagtat
     4861 taaaccctgc agtgatacca atggattggg caaaagccaa aacaagtgaa atatagcgcg
     4921 tcgcttgatt taatttacga cgtccaacct caccttgttt gccccactca acaaacttag
     4981 gtaaaatatc catctgcaat aactgaacaa cgatagaagc agtaatatat gggctaaccc
     5041 ccattgaaaa tactgagaaa tttctcatcg cattaccact aactaagttt aacatattta
     5101 agaaagggag ttcacttaat tgctctaagc tcttggcatt tacaccaggt acggtaatat
     5161 gtgtcccaat tcggaataca agaatgataa atatagtaaa gaaaatttta ttccgtacag
     5221 tctttatctt taacgcgtct tttagtattt ttaagaacat aatgagtatc ccctcattag
     5281 atgacttcga ttgaaccacc tttagcaata atagctgctt cagcagattt tgagaactta
     5341 gctgctttta cagtcaattt tttagtcaat tcaccgttac caagcacttt aacacctgat
     5401 ttttcagctc ggacaatacc agcatctttt aaaatagccg gagtcacttc tgtaccatca
     5461 tcaaaaacat tcagttgatc aagattcaca agtgcatatt ctttagtatt aatatttgta
     5521 aagccacgtt ttggaatacg acggaacaat ggtgtttgtc caccttcaaa acctaaacgt
     5581 acaccgccac cgctacgagc tttttgacct ttttgaccgc gaccagatgt tttaccatta
     5641 cctgatgatg tcccacgacc aacacggtta cgtactttac gtgagccttc agcagctttt
     5701 aattcatgaa gtttcatttt ttctcctttt tttgtaaaat gctagcgcct ctatgaggga
     5761 aaaggactcc ctatagaaac tcgcctatac attaatgata cttaagttat ccaaaataac
     5821 ttaatacaga tacgcactaa ccgactactg tttgttgcca aaaaagcaaa ctacaagagt
     5881 cggttttgtg ctcgttttta attatgaaat cagagatttc acagttataa cttatttaac
     5941 atcttcaacg gtaaccaagt gagaaatagc tgtcaccata ccacggatag cagcattatc
     6001 ttctttgact actgaagagt ttaatttacc aagtccaaga gcaacaacag ttttacgttg
     6061 ttctggctta cgtccgatag gagacttagt caaagtaatt ttaatttgag ccatgatgat
     6121 cccctttctt atgctaagtc agaaactgag atgccacgaa gtgcggcaac ttcttctgca
     6181 cgtttaagtt gtttcaatcc ttcaacagtt gcacgaacaa tgttgattgg agtgtttgaa
     6241 ccaagagatt ttgaagtaat atcagcaaca cctgctaatt cgatgacggc acgaactgca
     6301 ccaccagcag caactccaga accttctaca gctggtttca ataatacttt agctccaccg
     6361 aagttagtgt aaacttcgtg agggattgtt gtaccaacca ttggtacttc gatcatgttt
     6421 ttcttagcag cttcaactgc tttacggata gcttctggaa cttcttgagc tttaccagta
     6481 ccaaatccaa cacgaccatt tccatcacca acaactacaa gagctgcaaa gcgaagacga
     6541 cgtccacctt taacaacttt tgtaacgcgg ttaatcgcaa caacgcgttc ttcaagttca
     6601 actgcattat ctttaaatgc cattattttg tgtcctccct attagaattt caatccgttt
     6661 tcacgagctg catcagccaa ggctttaaca cgtccgtgat agagatatcc accgcggtca
     6721 aacaccactt cagaaatacc tttagccact gcacgttcag caacaagttt gccgactaca
     6781 acggcttgtt ctgtttttgt tcctttagaa acgtctttat caagagttga tgcacttgcg
     6841 agcgttacac ccgctacgtc atcaataact tgagcgtaga tgcctgtatt agaacggaat
     6901 acgttcaaac gtgggcgatc agcagttcca gagagtttac cgcggacgcg acggtggcgt
     6961 ttttggcgga ttttgttttt atctggtttc gaaatcacaa ttttcacctc ttaattttaa
     7021 tcaatttgtc tcattgacaa gttgtcgatt gaacttatcg agcatgttaa ggtgcaatac
     7081 ttcccatacc cgactaagaa cattatttac ctgttttacc ttctttaagg cgtacgtatt
     7141 caccaacgta acggatccct ttgcctttgt aaggctctgg tgaacgcaag ctacggatgt
     7201 aagcagctgt ttgaccaaca acttctttgt tgattccttc aactgagatt gaagttgggt
     7261 tagcaacagt gaaagtaatt ccttctggag cttcaacttc gtcttggtga gatttaccta
     7321 ctgaaaggac aagtttagta ccttgaagtt gagcacggta accgacaccc ttcatttcaa
     7381 gatctttttt gaaaccttca gaaacaccta caaccatgtt attcaagtta gcacgggttg
     7441 tcccatggat tgttttcatt tcttttgagt cgttaggacg tacaactgtg atttcagtcc
     7501 cttcaacttt gatttcaata tttttgttga actcacgagt gagttcgcct ttagggcctt
     7561 taacagtaat aacattgttg ttatttgtta attcaacgcc tgcaggcata gtaattactt
     7621 tattaccaat acgtgacatg tttattttct cctgttaaat tgtcaagccg catagcgact
     7681 agttttcacg gggtttgata gaatgatata cttcaattta tatttcaaaa ttgaacacga
     7741 gctgtggtct gtgtgaaaaa gataaatctt ccttgagtgt aaacacgcta cgtcagattt
     7801 cctattttca ctttgtccac gacgctctta gtatcttaaa ttaccaaacg taagcgatca
     7861 cttctccacc aacattcttt tggcgagctt ctttgtcagt caaaagacct tctgatgttg
     7921 aaatgattgc aattccaagt ccgttaagaa ctttaggcat gtcatcacgt tttgcgtaaa
     7981 cgcgaagacc tggttttgaa atacgtttta agttagtgat aacacgctca ccattttttc
     8041 cgtattttaa gaacacacga atgatgcctt gtttatcatc ttcgataact tcaacatttt
     8101 ttacaaaacc ttcacgttta agaatctcag caatcccttt tttaatgttt gaagcaggta
     8161 cttctaacac ttcgtgtttt acttgattag cattacggat acgtgttaaa aagtctgcaa
     8221 ttgggtcagt cataaccatt ttttatattc tcctcttact agcagtttga tgctatcact
     8281 tactagttaa tgttgtcctt aaaggacttt ggtatcagct tatgctcaca ccgttttaat
     8341 taagcacaag acttaatctg aagaacaaat taagttttgt gtcatatttt taccaagaag
     8401 ctttgacaac acctggaatt tgacctttgt aagccaattc acggaagcaa acacgacaaa
     8461 gtttaaactt gcggtaaact gaatgtggac gtccacattt ttcacagcga gtataagctt
     8521 gtgtagagtg ttttgcagga cgtttgttct tagcaatcat agatttttta gccaatttat
     8581 ttacccccta ttattttgca aaaggcattc caaggccctt aagcaattca cgtgattctt
     8641 cgtcagtatt tgcagtagtg acgattacaa tatcaagacc acgtacttta tcaacatcat
     8701 caaagctgat ttctgggaag ataagttgtt ctttcacacc gagagtgtag tttccacgtc
     8761 catcaaacga ttttgttgga acgccatgga agtcacgtac acgaggaagt gaaacgctaa
     8821 ccaatttgtc taggaattcg tacatacgtt cgccacggag ggtaactttt gcaccgatcg
     8881 ctacaccttc acgaagacgg aagccagcga ttgatttctt agctttagta ataagtggtt
     8941 tttgacctga gataagtgct aattcagctg cagctttctc taggtttttt gcgttggata
     9001 cagcatcacc aacacccata ttgagaacaa ttttctcaac ttttggcaca gccataactg
     9061 atgtgtaatt gaatttctct gtcaacgcag gaattacttc gttagtatat ttttctttta
     9121 aacgatttgc cattatgctt ctcctttcct tcgtgattaa tcaagcactt cgcctgattt
     9181 tttgctgtaa cgtacttttt taccgtcaac aactttataa ccaacacgtc cagctacacc
     9241 atttttatct aatacttgaa cattagagac atggataggt gcttcttttt cgacgatagc
     9301 tccttgagga ttttcagtgt taggtttttg gtgtttttta atcattccaa caccttcaac
     9361 aataactttg ttaacttttg gaagtgcttt aagaactaca gcttcagtgc ctttgtcctt
     9421 gccagcaatt acgcgaactt tgtcgccttt ttttacaaac attctggttt ctcctattat
     9481 ttcttacgcc ccgatgggca ccctaggaaa acctagggga ctacgtttgt taatctgata
     9541 ttaaagtact tctggtgcaa gtgatacgat cttcatgtag ccaccctcac gcaattcgcg
     9601 tgcaactggg ccaaagatac gagttccgcg aggagtttta tcatcacgga tgattacagc
     9661 agcattgtcg tcaaatttga tgtatgaacc gtctggacgg cgtgcaccag tttttgtacg
     9721 aacgataaca gctttaacca catcaccttt tttaactgct ccaccaggag tagcttgttt
     9781 tacagaagca acgattacgt caccgatgtt agcgaattta cgtcctgaac caccaagtac
     9841 tttgatagtc aagatctcac gagcaccgct attatcagca actttcaagc gagtttcttg
     9901 ttgaatcatt tcaattttct ccttttagtt tgattagata ataacagctt cttccactac
     9961 ttccacaaga cggaaacgtt ttgtagctga aagtgggcga gtttccatga tacgaacgat
    10021 atcgccttct ttagcaacgt tgttttcatc atgtgcttta tattttttag aatagttgat
    10081 acgtttacca tagactgggt ggttacgttt agtttcaact acaactgtga ttgttttgtc
    10141 catcttgtca gacactacgc gtccgtaaag agttttacgt tgattacgtt ccatttagaa
    10201 tttctccttt cccaatctat tatttcattt ctgattgcac agttttaaca cgtgcaattt
    10261 gtttcttaac ttcgtcaagg cgagcagtct tttcaagttg acctgctgca gcttggaaac
    10321 gaagatcaaa caattctttt ttgagttcgt tttctttctt agcaagttct tcttgagaca
    10381 atccacgaag ctctttaaca aaatctttaa tttcttgaag tttcatgtct tctccttatt
    10441 ctgcttcacg ttttacgaat ttgcacttaa ctggtaattt gtggctagca agacgtaatg
    10501 cttcgcgagc aatttcttca gaaacaccag caatttcaaa catcacttta ccacgtttaa
    10561 ctggtgctac ccaaccttca ggtgcccctt taccagaacc catacgtaca ccgatagctt
    10621 ttgcagtgta tgatttgtgt gggaagattt taatccaaac tttaccacca cgtttcatgt
    10681 aacgagtcat cgcaatacgg gcagcttcga tttgacggtt tgtaatccag tggctagttg
    10741 tggcttgaag tccgtattca ccgaatgaaa cttctttacc acctttagcc tcaccgcgca
    10801 tttttccacg gaattcgcga cggtgtttaa cacgtttagg tactaacatt tgttatttgc
    10861 ctcctttagt gtttttacga gctggaagaa cttctccacg gtaaatccaa actttaacgc
    10921 caagtttacc ataagttgtg tcagcttctt cccaagcata gtcgatatca gcgcgaagcg
    10981 tgtgaagtgg aacagttcct tctgaataac cttcagcacg agcgatatca gcaccgttca
    11041 aacgaccaga aacttgagtt ttaatccctt tagctcctgc acgcattgta cgttggattg
    11101 cttgtttttg agcacgacgg aaagcaacac gttgctcaag ttgacgagca atattttcac
    11161 caacaaggtg agcatctaaa tcaggttgtt tgatttcgat gatgttgatg tgtacttgtt
    11221 ttccagttaa tttgttaagt tgaccacgaa gagcgtcaac gtttgcgcca cctttaccga
    11281 taaccatacc tggtttagca gtgtgaagtg aaacaataac tttgtttact gcacgttcaa
    11341 tttcaatagt tgaaactgat gcgtcagcta attctttatt aatgaattta cggattgcaa
    11401 gatcttcatg aaggtaatcc gcgtattctt tttcagcata ccatttcgca tcccagtcac
    11461 ggatgattcc gacacgcata ccaattggat gtactttttg acccacgatt ttacctcctt
    11521 atttttctga tacaactaca gttacgtgag ttgtacgttt gttgattggt gaagctgaac
    11581 ctttcgcacg tggacggaaa cgtttcattg ttggtccttc gttagcgaat gtttcagata
    11641 ctaccaagtt tgctttttcc aaaccaaagt tgttttctgc gttagcaatt gctgagttaa
    11701 gagttttctc aataacacga gctgctttgt ttggagtgaa ttttaagatt gcgattgcgt
    11761 cagcaacttt cttaccacgg ataagatcaa gtactaaacg tgttttacga ggtgaaacac
    11821 gcactgtacg agccattgct ttagctgaag taatttctgc cattgtgtcc tcctcctatt
    11881 aacgacgtgt tttcttgtcg tcagctgcgt gacctttgta agtacgtgtt ggtgcaaatt
    11941 caccaagttt gtgacctacc atgtcttctt ggatgtaaac aggtacatgt ttacgtccgt
    12001 cataaactgc gattgtatat ccaatgaaac ttgggaaaat cgttgaacga cgtgaccaag
    12061 ttttgattac ttttttcttt tcgtcgtttg cttgagcttc aacttttttc atcaaatgct
    12121 catcgacgaa aggtcctttt ttaagactac gtcccatttt gtagttttct cctttaaata
    12181 atgtaccaca gcggcttgag ttcaagagca agactccaaa ctctaccgag ttggcggaat
    12241 aaatagcaaa gctattgtaa cgctatttca gcaagtttta agcaacttac taagattatt
    12301 tttcgttacg acgacgaacg ataagtttgt ctgatttagc tttcttgtta cgagttttaa
    12361 gaccaagcgc tggtttaccc catggagttg atggcgcttt acgtccaact ggtgctttac
    12421 cttcaccacc accgtgtggg tgatcgttag ggttcattac agaaccacga actgttgggc
    12481 ggataccttt ccaacggcta cgtcctgctt taccaatgtt aacaagtgat tgttgttcgt
    12541 taccaacagt accgatagtt gcacggcatg taccaagaat catacgaact tcgcctgatt
    12601 gaagacgaac aagaacgtat ttaccttctt gaccaagtac ttgagcagaa gctccagctg
    12661 cacgaacaag ttctccacct ttaccaggtt tcaactcaat attgtgaaca actgtaccga
    12721 caggaatgtt tgctaatgga agtgcgttac caactttgat atctgcatct ggaccagaaa
    12781 caatacgttg acctacttca agacctttag gtgcaatgat gtaagctttc acaccgtcag
    12841 tgtaatgtac aagtgcgatg tttgcagtac ggtttggatc gtattcgatt gttttaacaa
    12901 ctgcttcaac gccatctttg ttacgtttga agtcgatcaa acggtaatga cgtttgtgtc
    12961 caccaccttg gtgacgaact gtgatgcgac cattgttgtt acgaccagct ttgctcttaa
    13021 gagaaacaag caatgatttc tcaggcgtgc ttgttgtgat ttccgcgaaa tccaaagaag
    13081 tcatgttacg acggccattt gtcgttggtt tataaacttt aatacccacg ttatttcctc
    13141 cttagattat tcagcttcag ctgcgaacaa ctcgattgct ttagaatcag ctgtaagagt
    13201 gatgatggct tttttagttt ttgaagtgaa acctgtgtaa cgaccaacgc gttttgcttt
    13261 tggtttaacg ttaacagtgt ttacacttgc aactttaact ccgtcaaaag cagcttcaac
    13321 agcttgtttg atcaaaagtt tgtgtgcacg agtatcaact tcgaaagtgt atttgcctgc
    13381 ttcaagagca atcattgact tctcagtgat aactggtttt ttgattacgt cgtacaaatt
    13441 cattatgcaa gaacctcctc aattgtagag attgcttctt tagtaacaag aagtttgtct
    13501 gcgttcacga tatcaagaac acttgcagtt gctgcagttg caacagttac gtttggaagg
    13561 ttacgtgcag aaagtgctgc aaattcattt ccttcttcaa caagaacaag tacttttgta
    13621 tcaatgctaa gagctgaaag cacttttgca aattcagcag tttttggtgc tgcaaatgaa
    13681 aggccttcta cagctacaaa tttatcttca gcaacttttg ctgagtaaac tgatttcaac
    13741 gcaaggcgac gaactttttg tggaagtttg tatccgtatg aacggggagt tggtccaaag
    13801 acaacaccac caccacgcca ttgtggtgag cggatagaac cttgacgagc gcgtccagtt
    13861 cctttttgac gccatggttt acgtccaccg cctgatactg ctgaacggtt tttaaccgca
    13921 tgagtacctt ggcgaaggct agcgcgttgg ctaattacaa catcaaaaac aactgattcg
    13981 tttggttcga taccgaagat agcgtcgttt aattcaactg agctaacttc tttaccagtt
    14041 tggtcaaata gttttacgtt tgccatttta actgttttct cctttcttat tatttagcag
    14101 ctttaactgc tgacttgata gtgataagag atttcttagc acctggtacg ttacctttaa
    14161 caaggataac gttcttttct aggataactt gtacaatttc aaggttttga actgttacac
    14221 ggttaccacc catacgtcct gccaagcgtt tgtttttgaa aacgcggtta ggcgcaacag
    14281 gtcccataga acctgggcga cgatggtaac gagaaccgtg agccatagga ccacgtgatt
    14341 gaccatggcg tttgataaca ccttggaaac ctttaccttt tgatgtccct gtgacgtcaa
    14401 caacatcacc agcttcaaat tgttctacag ataattctgc accaacttct aagccttcaa
    14461 tgtttttgaa ttcacgaatg aagcgcttag gagctgtgtt tgcttttgca acatggcctt
    14521 tggcaggttt gttactcaag acttcacgtt tgtcatcaaa accaacctga actgcttcat
    14581 aaccgtctgt ttcaacagtt ttaacttgaa gcacaacgtt tggagttgct tcaatgacag
    14641 taacagggat gaattcgcct gattcagtga agatttgagt cattcccact tttttcccta
    14701 agattccttt tgtcatgaga aaatatttcc ttttcttaat aatatttcaa aaagtttttt
    14761 atgagcgttt tttgtgctca aaaaagtttt ttacgagcgt tttttgtgct catagcaaga
    14821 tacaaagagc gtcaaactca aaataaaaat agaaaatcta acacaaaaac ttctgtttcg
    14881 aggaagattt atctttttca tgtagagttt agctcgtgtt caagttccat caaacactaa
    14941 ctgtacttgc aaaatctcac cgattaaagt ttgatttcta cgttgacacc acttggaaga
    15001 tcaagtttca tcaaagcatc aacagttttt tgtgttggat tgatgatgtc taccaaacgt
    15061 ttgtgtgtac gcatttcaaa ttgttcgcga gaatctttgt atttgtgagt cgcacgaata
    15121 attgtgtaaa gactgcgttc agttggaagt ggaactggtc cagcaactgt agcacctgta
    15181 cgtgttgcag tttcaacgat tttttctgcc gctgtatcaa gtgtacggtg ttcgtacgct
    15241 ttcaaacgga tacggatttt tttgtttgcc atcttttctc ctctcgtcta tttacgataa
    15301 taggctagct cctcaagaaa accgacacct gttgcgtggc aatgcaaccg agcgtgtcgc
    15361 aacctcttgt atcattgcta aagctgtatt tttacagcac cataatataa taacagaatc
    15421 atttagtcat tgcaagcttt ttaggcattt ttttcaaaaa aactaccttc ctaatgaaag
    15481 gtaatttctt ggtacttttt aaattgttta gagagaataa accaccgact ggtattatct
    15541 aacactgtcg ccatccagac ccctatgagt ccatattgcc aaaccacacc aatcacataa
    15601 ccaaggccaa tgcgaatcac ccacattcct atggttgttg catagaaagg aagctttgct
    15661 tttcccaaac cctgccagac ggctgtataa actaaagtgc ctgccgttgc gggagctcct
    15721 agtaaagaaa aaagtaaaac aaccatggcg gacctttgag catcagtatt ctgagtaaat
    15781 agcggcaaga gactaggacc tagcagatag gtcaaggctc ccataaccag catcatgagg
    15841 gtggataaaa taaaagcttc tctaataata taccttatct cagtcacctt accgcccccc
    15901 agttgcctag ccactagaat aattgttgct gttgccatgg ctaagccagg catgtaatta
    15961 aactgagtca aggtttctcc aatagcatta cctgccaagg ccgttgtccc aaagcgaaca
    16021 acaatgccaa taattaggac atctcctgct ctcatcatca aacgttcacc agcagcaggt
    16081 agtgataaat caaaaataat tttgtccaaa ggtctcatca atcgtttcgc aacctgttta
    16141 ataggaataa actgacaaag taaaaacaca cccactaaac gagataaaac cgtcgcccaa
    16201 gcaacaccaa gaagaccaaa tccccataca tagatagaca aggcagaaaa aatggcattg
    16261 agtacgttta ttaataagct cacctgcata ggaatcttag gatacccttg agctcgaaca
    16321 atagctccta agctagttaa aagtcctaga ctaacaatca taccgccgac aatggataga
    16381 tattgccctc caaccaatgt tacagaagct tcagctccta gccattctaa cacctgatga
    16441 tgtccaacaa ctgataacaa ccctaagccg accgaaagga ggagtgttac ttgcaagaca
    16501 cctgccatat agtttaattg tttgttctga ttattttctc caatacttcg agcaatcaga
    16561 ctagatacag cagctcccag cgcgataaag agggactgat aaatactgat aatgttgtta
    16621 gctatggaga caccagagac tgctacaagt ccaatttgag ccaccaggta attatcaacc
    16681 attcccatta acatctgtaa aatattttct atcatagaag gcagagctaa agagaaaatt
    16741 tttcttctat tatatatcat ttatgtcccc taataaaaaa ttcttgatca aacgattttt
    16801 tcaaacacag tcactggact cattcagtta ttttggtcca ttaatgaatt cataaagtct
    16861 atcttaatag cagagtccca agatacacga cacttagtgc tacagtaaca attgaccaca
    16921 tgccaatcct taacatttac ctaacgttta taactaagaa gatgaagaac aaaaggactc
    16981 caaacgaatt ttttctatta tataatatat tcttcattta gcaactttca atgtatcaaa
    17041 atagcgctct cgagtcaaaa atgttttctg atactcgaga gtgctatttt atttggaatc
    17101 aagtttaagc aacttaggct tatctcatat ttaatacatt tgtatgttta gctgatgaaa
    17161 tctaagacct tgcgcccttg gattaaacca cgttccattt catcaaagac ttctggagca
    17221 gtgtcaactg gaactttttc gacaaccgga gcaaccagac cttctgcacc aaaggcaaag
    17281 gcttcttcca agtctttacg tgtccctaca agtgatccga ccactttgat accatctaaa
    17341 acagttttta cgatagacag ttccatgtat tctgacggaa gacctacggc tacaactgtt
    17401 ccaccggcac ggacactatc aattgcttgg ttaaaagcaa ctttagaaac agccgttacc
    17461 acaacaccat gtgctccacc gattttttct tgaatatagc ctggaacatc ttcaatttct
    17521 ttgccgttaa ctaaaatatc tgcgccaact tctttagcta actcaagttt atcattatta
    17581 atgtccactg cgacaacatg agcattaaag actttcttag cgtattgaac agctaggttt
    17641 ccaagacccc cagcaccaaa aataacaatc cattgacctg gagcagcacc tgcctcttta
    17701 atagctttat aagttgttac accagcacaa gtaatggaag aagcttgagc cgggtctaaa
    17761 ccttctggaa ctttaactgc ataatcagct gttactactg catattcact cattcctcca
    17821 tcaacactgt atccagcatt tttaacacta cgacaaagtg tctcacgtcc tgtagtacag
    17881 tattcgcaat gaccacatcc ttcaaagaac catgcaatag agacacgatc accaaccttt
    17941 aaggatgtta cgccttctcc aatttcttct actataccaa taccttcgtg ccccaaaata
    18001 cgtcctggta cctgaccaaa atcgccatgt gcaacgtgta aatcagtatg acaaacgcca
    18061 cagtattcta ctttaacaag cgcttcacca tgaccaacat ttggaagatc atgctcaaca
    18121 acttcgacac ctgtactagc ttgattaaca actacggctt tcatatcagt cctccatcta
    18181 ataacgactt atttgtaatc ggttacaaat aaattgtaca tcttttcaca attaaagtca
    18241 acagaaacct gaaaagtttc tgaaacttaa ctggttaatc ttatagctgt ttgcctatct
    18301 gcaaaatact taactacatt ttctgacact ggatataaat gatatattta gaaaataaaa
    18361 tgatttctta tgactttaat cataagaaat catttcctgg tatcaacatt aaaaatcact
    18421 tacgtcgtcc tggacgttca gcataaccat agtaagcatc ttcaataatt tcttgcatgt
    18481 gatcaaccat tggaagacgt gggttagcag gtgaacattg gtcttcataa gcaaggtaag
    18541 ccaattcacg agaatgttct ttccattcat tttcgtcgat accttgagct ttgaagttca
    18601 tttgaatacc aactcggcaa cccagatcat aaacagcttt cgcataagat tccactgctt
    18661 cttctggtgt agaagctgga agccctaaca atttcgcaat gtcttggtat ttttcatccg
    18721 cacggtagta attatactta ggccatgtcg ccgttttagc tggacgagtt ccattatagc
    18781 ggataacata cggcaaaaga attgcatttg tacgtccgtg tacggtatgg aattgtgcgc
    18841 caattttatg cgccattgag tgagaaatac ctaagaatgc attggcgaaa gccatacctg
    18901 ccatagttga cgcattgtgc atcttttcac gtgcttcaaa atcggctgtt ttaactgatt
    18961 tttcaagatt atcaaaaaca attttaatgg cttgaagagc taaaccatcc gtaaagtcat
    19021 tggccatttg tgacacgtaa gcttcggttg cgtgtgtcaa aacgtccata ccagtatcag
    19081 cagcaataaa gcctggaaca gtcaatacca aagctgggtc aacaatggct acagttggtg
    19141 ttaatgagta atcagcgatt ggatatttac gattatttgc tttgtcagag ataacggcaa
    19201 atggtgtcac ctctgaacct gttccagaag ttgttgggat agcaacaaat tttgttttct
    19261 taccaagttc tgggaatttg aacgcacgtt tgcggatatc catgaatttt tgaacgaggt
    19321 catggaaatc aacttctggt tgttcataaa agagccacat aactttggct gcatccatag
    19381 gagatccccc gccaagggca ataatggtgt ctggtttgaa ggtacgcatt aattcagtac
    19441 ctttcataac agttgtaatg tctggatctg gttctacttc agcaaagatc tgataaacaa
    19501 ctttattgcg acgaagatca agttgttcaa tgatacgatc caagaaacca agctcaacca
    19561 tagcgtgatc tgtaacaatc atgacacgtt caacatcacg acatttttgc aaatattgaa
    19621 ttgaatcacg ttcgaagtat gtttttgaag gaactttaaa ccattgcata ttatttctac
    19681 gtcttcctac ttttttgatg ttcaagagat ttatagcact aacgttatca ccaactgcgt
    19741 tacgtccata cgaaccacaa ccaagagtca atgatggtaa gaaagcattg taaacatccc
    19801 cgataccacc aaatgtagaa ggtgaattcc agatgacgcg gatagcacgg attctagttc
    19861 caaattcttt tgccaactct gcatctgctg tatgaatggc agctgagtga ccaagtccat
    19921 taaattcaac catttgacga gctttttcaa caccgtcttc acgtgattca gatttcaaaa
    19981 cagcaatgac tggagataat ttttcacgtg ttaaaggctc attttctgaa acttctttac
    20041 attctgcagc aagaatattc gttccttctg gaacagtaaa tccagcttgt gctgcaatcc
    20101 aagtagctgg ttttcctaca atatttggat ttaattttgc accagcacag tttttgctat
    20161 ttgcttttgc accaaaacag aattcttcaa gaagagcttt ttctttttta ttaacaaaat
    20221 aagtgtggta agatttgaat tctgctacaa aatcgtcata gatttcttta tcgatgataa
    20281 cagcttgttc agaggcacag accataccat tatcaaatga tttagacatc acaatatcat
    20341 gagcggcttg acggatatta gcagattttt ccacataggc tggaacatta cctgcaccta
    20401 ccccaagagc aggttttcca catgagtaag ctgctttaac catcgcattt ccacctgtcg
    20461 caaggatagt ggcaatgccg tcatgattca tcaaagcatt tgttgcttca agtgatggtg
    20521 tttcaaccca ctgcacacaa ttttcaggag caccagcggc aatagcagca tcacgaacaa
    20581 tacgagcggc atgtgctgat gattcttgtg ctgatgggtg aaaggcaaaa ataattggat
    20641 tacgtgtttt taacgagatc aaagatttaa agatagctgt tgaagttggg ttagttgttg
    20701 gtgtaatccc acagataaca ccaaccggct cagcaatcaa cgtcaaacct gtcacgtcat
    20761 cctcttcaat aattcctact gttttttgat ggcgcatgtt attaaccaca tgctcacaag
    20821 caaatagatt ttttgttgct ttatcttcaa agacaccacg acctgtttct tcgtaagcat
    20881 gtttagcaag ttctccgtgt gcatccaagg cagcaacaga agcttttgct acgatatagt
    20941 caacttgttc ttggtcaagc ttacgcatct cttcaagagc agctaaacct ttttgaacaa
    21001 gagcatcaat tgtcacagaa acagaggttg tttcaacagt attatgtcct tcagtcattt
    21061 gagactcctt tatcttgtta aaagtttcac aattttgttt acaaaattat tatagcactt
    21121 tttgaaattt tgtaaatcat ttcacgataa atttgtgaag tttttttcaa attatttctg
    21181 aaatcctatg gtatcaatat tcttcattaa ctttttttca gaaatatatc taaaaaaagc
    21241 cgttttattt ctgaaaccgc tttcttttga aaacctcaaa gtactactat tttaccatca
    21301 tcatttgttc acaagaaaaa gccagagcac aatggatctg acttatctct tagacatttt
    21361 ttaactttat ttagctggtt ttttagctga cttctcaaca gcagtctgga ttgtggaggc
    21421 atatagttct gctccttgac tatcttcact ataatgaaca ccatcactgc cataccaaat
    21481 atctggatgt tcaacagcaa ctttatacca gtctgcaata gtgacatact tgtatttttt
    21541 ggacaattta agaccatagt ctctagcttc tgcaacctga ctggcatttt tggcattata
    21601 tggagaaacc aaaactaaac gatgaccttt tggcaatgcc tcaataaaag actgaactgc
    21661 ttgagaatag ttgtcaagcg agttaacacc tactgctaag acaacagtct tagatagact
    21721 cttagattta atttggttat taaataaatc gaaagcttct ttaaaattcc gactgaccgc
    21781 tgcatccagt tgcgcttgtg gcataatttt tgagaatgcc gcactagagc gtaatgcta
//
LOCUS       DAXMQE010000030        21778 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.030, whole genome shotgun sequence.
ACCESSION   DAXMQE010000030 DAXMQE010000000
VERSION     DAXMQE010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21778)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21778)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21778
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.030"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            20..502
                     /locus_tag="ACF4ZO_001362"
     CDS             20..502
                     /locus_tag="ACF4ZO_001362"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFD5486891.1"
                     /translation="MTDIKILDACCGSRLFWFDKNEPHTTFMDVRQEKFEMHGKKINV
                     NPDVIGDFRDMPFESNSFNLVVFDPPHLKYVGQNSIMKAQYGQLDKENWKEDISKGFE
                     ECMRVLKVGGTLVFKWSDCQVNVREVLSAIPFKPLFGQQRGTTHWMTFVKFELTGNGG
                     "
     gene            492..1256
                     /locus_tag="ACF4ZO_001363"
     CDS             492..1256
                     /locus_tag="ACF4ZO_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HFD5486892.1"
                     /translation="MGDSDVKCELYNDHFENAKRYNIPRAQLIIADIPYNLGNNAYAS
                     DPRWYENGSNKNGESKLAGKSFFDTDNDFKINNFFDFCSRLLRKEPKEKGKAPAMIVF
                     HAWQQRELVIACGKKHGFNNAYPLYFTKKSSPQVLKANMKIVGAVEEATVLYRDKLPK
                     FNNSGAMILNHAPWEKDSSYPVIHPTQKPIPVLKRLIEIFTDPDDVVIDPVAGSGSTI
                     RAAIEMNRNAYGFEIKKDFYKRAKEEMLSTFQTSLF"
     gene            1304..1597
                     /locus_tag="ACF4ZO_001364"
     CDS             1304..1597
                     /locus_tag="ACF4ZO_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486893.1"
                     /translation="MNTNEKVIDTICHIRHYGDRYDMCQDMRSWVAERNGLIQDLLKA
                     KKQIDRNRIAKRLDRAQKNISDIITKVTGDLWQGSDQVIAEQCFLKVLEEMQK"
     gene            1962..2399
                     /locus_tag="ACF4ZO_001365"
     CDS             1962..2399
                     /locus_tag="ACF4ZO_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HFD5486894.1"
                     /translation="MGNIPTPKANNFLEELKTIPHLIETLERDANLMSRSLVKSPQWS
                     DMRVSGGVKQSQEDKNIKMLHMVSYYSDQIERLKDRRQEMANLIVQSMGICESHVLLT
                     TYLDCDGDYERARERLNIGNRNKYFMFVRRGKESLELILKNTN"
     gene            3258..3740
                     /locus_tag="ACF4ZO_001366"
     CDS             3258..3740
                     /locus_tag="ACF4ZO_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0051276 - chromosome organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HFD5486895.1"
                     /translation="MDWRWWKIAYEELTEKQQRFVDKYITTFNATESAKQAGYSEKSA
                     YSQGQRLLKNVEIQKAMKERFLEAKDTKGDRIQDVAETLEQDTSIARGEIQISEFKET
                     DMLTGQVVIHTKREYTPSHEEQGRARDRIYKVNGAYSEKRELEHSGTVVFANEDNIPD
                     "
     gene            3718..5007
                     /locus_tag="ACF4ZO_001367"
     CDS             3718..5007
                     /locus_tag="ACF4ZO_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HFD5486896.1"
                     /translation="MKTTSLIKVDLPSTIGIGYGAFWRSRNFYRVVKGSRGSKKSKTT
                     ALNFIVRLLKYPWANLLVIRRYSNTNKQSTYTDFKWACNQLKVSHLFKFNESLPEITV
                     KATGQKILFRGLDDELKITSITVDVGALCWAWFEEAYQIETEDKFSTVVESIRGSLDA
                     PDFFKQITVTFNPWSERHWLKRVFFDEETKRDDTFSGTTTFRVNEWLDDVDKRRYEDL
                     YKTNPRRARIVCDGEWGVAEGLVFDNFEVVDFDVEKTIQRVKETSAGMDFGFTQDPTT
                     LICVAVDLVNKELWLYNEHYQKAMLTDHIVKMIRDKNMHKSYIAADSAEKRLIAEIKS
                     KGVSGIVASLKGKGSIMQGVQFMQGFKIYIHPSCEHTIEEFNTYTFKQDKEGNWLNEP
                     IDKNNHVIDAIRYALEKYHIRSNESNQFEVLRAGFGY"
     gene            5019..6521
                     /locus_tag="ACF4ZO_001368"
     CDS             5019..6521
                     /locus_tag="ACF4ZO_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0046798 - viral portal complex [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0051027 - DNA transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HFD5486897.1"
                     /translation="MYTESFRDSTGKTKTLEFRFHREARMRYQAESLESLLTEKYKLL
                     REMIEHHDKVQKPRIQELLDYAEGNNHTISEIGRRKDDDMADVRAVHNYGKYISTLKQ
                     GYLVGNPIRVEYIDGTEQQQDLLKDLSVKNNFHQLNRRLVKDLSKVGRAFELIYRSMD
                     DKTEVVRLDPREVFVIYQNNLEQSSLAGVRYYNKNQLDGTTKIVELYTDNKILKFEYD
                     GDLTPIGEISSHAFGSVPITEYLNTDDGMGDYETELSLIDLYDAAQSDTANYMQDLSD
                     AILAIIGRVSFPGYVDTAEKAIEYLRKMRKARLLNLEPPVDQDGREGSVDAKYLYKQY
                     DVNGTEAYKTRIVSDIHKFTNTPDMTDSKFAGQQSGEALKWKVFGLDQERVDMQALFE
                     QSLKRRYKLIARISQLLKEIDGFDINRLKITFTPNLPKSLQEKIEAFKALGGELSQET
                     AMAITDIVEDAKKEISLINSESKSRSQLAQKLEETSRLTDRELAHDHQKE"
     gene            6502..8065
                     /locus_tag="ACF4ZO_001369"
                     /pseudo
     CDS             6502..8065
                     /locus_tag="ACF4ZO_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560958.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage head morphogenesis protein"
     gene            8069..8254
                     /locus_tag="ACF4ZO_001370"
     CDS             8069..8254
                     /locus_tag="ACF4ZO_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486898.1"
                     /translation="MDFSDFLNKKQKEWDESHPIPDFSAMSDEELLYQPMSEALVSER
                     FAKELSKEVRKRNLLSK"
     gene            8325..8552
                     /locus_tag="ACF4ZO_001371"
     CDS             8325..8552
                     /locus_tag="ACF4ZO_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008088029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486899.1"
                     /translation="MNKRLKKKRKLETAVVILIKEVAELRSIVSANAQATNNELATVK
                     AATLDTQSAIKSIGDDVDYIKKNYKRKWGKK"
     gene            8549..8830
                     /locus_tag="ACF4ZO_001372"
     CDS             8549..8830
                     /locus_tag="ACF4ZO_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004562043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486900.1"
                     /translation="MKYRKKPVEVEAFQWYGDIRQKEDPEWIISAISEERAWIEVDKV
                     VNSPVLRINTLEGVMTANQGDYIIKDVAGEFYPCKPDIFEQTYEPNPKS"
     gene            8994..9614
                     /locus_tag="ACF4ZO_001373"
     CDS             8994..9614
                     /locus_tag="ACF4ZO_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HFD5486901.1"
                     /translation="MTKELLAKLFKCAPDTGTGSEGVSDVDNQQNDTDGESSSGDGFK
                     APQSQSELDSYTNKAIQKALENQRKDEAKRIDDAVKNALAKEKDYSKLSEEERQQREF
                     EDSKKAFEAEKAKFEHDKLVVQVEKDLIAKGLPSEFAELLATKDAEDALEQAKTFEVA
                     FKKAVAEEVKKTVRQETPANGGGLSKQTNYGANLASKAAQQSTKLF"
     gene            9624..9992
                     /locus_tag="ACF4ZO_001374"
     CDS             9624..9992
                     /locus_tag="ACF4ZO_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="head decoration protein"
                     /protein_id="HFD5486902.1"
                     /translation="MNKRKVITSKEILHNLDYEAISVTLDSDEIGKKVVPAGTVLAGV
                     SESVFKDRKQKVKAVDDSADYIDGILLTDVDLTNGDAAGSCVYRGTINADKLADSSVA
                     KNYENLEEVLPHIQFIKGGK"
     gene            9995..11077
                     /locus_tag="ACF4ZO_001375"
     CDS             9995..11077
                     /locus_tag="ACF4ZO_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="major capsid protein"
                     /protein_id="HFD5486903.1"
                     /translation="MALIHEIITSENIKGFYNAKNENVGNTLGENAFPPKQQLGLELS
                     FIKGAAGKPVTLKAAAFDTKVPLRDRMAVELLNEKMPFFKEAMVVKEADRQQLSLLAQ
                     TKNQELIDTALAAIYNDKVTLIAGAKARLEAMRMEVLSKGKIHVASNGVMKDFDYGLD
                     SSQTTKPDTKWEQADTATPLKDIEKAIEAMAERGFVPEAIIMNSKTLSLIKNASNTLD
                     VVKPMAPDGAAVTKGDLETYIADELGLKILLKDGMFVGDDGKAKKYFPDGFATLVPNG
                     NLGYTVFGTTPEQSDLLGGEATDAEVSIVETGIAITTTKTTDPVNVQTKVSMIALPSF
                     ERLEEVQIINATESEEETKKENSFEM"
     gene            11087..11329
                     /locus_tag="ACF4ZO_001376"
     CDS             11087..11329
                     /locus_tag="ACF4ZO_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HeH/LEM domain-containing protein"
                     /protein_id="HFD5486904.1"
                     /translation="MPRVIRAFKDKVTKVVYEVGDIYSGDRVEFLTEGGVLEPSVDFD
                     KLKVSEIKSKLDELNVGYDAKLKKSELLKLLKQAIG"
     gene            11343..11696
                     /locus_tag="ACF4ZO_001377"
     CDS             11343..11696
                     /locus_tag="ACF4ZO_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HFD5486905.1"
                     /translation="MDAVNTSSVISNVKLDLGILDSQQDDLLNMLLKRVTDHFKAKYG
                     VVKIDSAFSFVLEDCLIARFNRRGAERAKSESVEGHTTTYYDFLDEFEPYDNMIMAKL
                     DLIKDKSRKGGLYFL"
     gene            11693..12001
                     /locus_tag="ACF4ZO_001378"
     CDS             11693..12001
                     /locus_tag="ACF4ZO_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486906.1"
                     /translation="MRYADRVTFVKTTDERYDPDLGEYTHTETISETKPCFAMEMGVE
                     KSVQIFGDYQKDRKVIYLKQPYTKAFDYCEYEGKRYKAQANKLGAIVFYLEGDDSIGS
                     "
     gene            11982..12347
                     /locus_tag="ACF4ZO_001379"
     CDS             11982..12347
                     /locus_tag="ACF4ZO_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97-gp10 family putative phage morphogenesis
                     protein"
                     /protein_id="HFD5486907.1"
                     /translation="MILLVADISLKVVGTAGLKNKLELIIKKDAVKKIVRDNGNQLQR
                     KMINKAVFTKGYSTGATRRSITMEIGDGGLSVTVKPGTHYAGYLERGTRLMDKQPFVL
                     PALKEQKVKFRKDLEALVK"
     gene            12344..12733
                     /locus_tag="ACF4ZO_001380"
     CDS             12344..12733
                     /locus_tag="ACF4ZO_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage capsid protein"
                     /protein_id="HFD5486908.1"
                     /translation="MIKTRDQSIFDEMYKRIQSLNYDVYDYKPPLEVPYPFVEMESTD
                     AEYIPNKDDIKGSVELTLSVWGLQKKRKQVSDMASAIFSQALAVESSDSFYWSFNSRQ
                     SSVQILDDTTTVTPLKRAIVTLRFNLR"
     gene            12803..13366
                     /locus_tag="ACF4ZO_001381"
     CDS             12803..13366
                     /locus_tag="ACF4ZO_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage major tail protein, TP901-1 family"
                     /protein_id="HFD5486909.1"
                     /translation="MTAQTQPKQLEAKQGIHSILLFRLLKEASEKPATKLAFQTEHEV
                     GKSRDVDSKKTKDGIIQSVGALEYDFKATSILAKGDELAAKLEEAMEKGELVEIWDID
                     SEEASKKNGSNKYPATYYQGYISSFSAKKNAEENIEIEMEFAINGVGQKGDATLTDAQ
                     KAAVQYNFKDTTKSNGEETKKENSFEM"
     gene            13418..13777
                     /locus_tag="ACF4ZO_001382"
     CDS             13418..13777
                     /locus_tag="ACF4ZO_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail assembly chaperone"
                     /protein_id="HFD5486910.1"
                     /translation="MQLEIKGKTHNVKFGTRFVAEMDKNHVTERDGMKFGTGLQSTVP
                     FLFERNVVTLAEIIHVGTITESPRPSLNDIYDYIDEVDDIEKLFNDVLDELRQSNASK
                     LFMARVEKNLAEVAAEA"
     gene            13819..14148
                     /locus_tag="ACF4ZO_001383"
     CDS             13819..14148
                     /locus_tag="ACF4ZO_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486911.1"
                     /translation="MIVLNCIRYLGMTDINEIGRLTLYEYDLLMTGKALAAVDESHKA
                     HKQAWINHQVTATKLVGGKKNKKEVPVYKKFKDFFDYEEEIRKITQEIDEGYDKKGMD
                     LLLKANL"
     gene            14163..17798
                     /locus_tag="ACF4ZO_001384"
     CDS             14163..17798
                     /locus_tag="ACF4ZO_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HFD5486912.1"
                     /translation="MGESYSVEAVLTAVDKTFGKTLQSAIRSIDGLEKRSRGFSSVSQ
                     RAGSMFKNMLGANLAGQAISAMTRTVSSGLGSMLGEMNSSAKAWKTFDANLADIGFGK
                     KQILAAKTAMQDYATKTIYSASDMASTYAQLAAVGVKDTGKLVKAFGGLAASAENPKQ
                     AMKSISQQMTQAVGRPTVAWQDFRIMLEQAPAGMAKVAKSMGKNLDELVADIQAGRVK
                     TSDFLEAVKKAGNDKSFQKMATEFKTVDQAIDGMREGLSNKLQPAFEKVNQFGIRAFK
                     SIAEQLDKVDFSRFANNIGKFLEGINIEKVISRVATSISSVVSKIKEFWDGFKQTGAI
                     SAFSGALKSVWGALKNVASAMSGGSWKNFGSIVGGIVKHVSNFAKAIADVVGKMEPGR
                     LQSWIATFAAVGGGFKLFEKLTGQSVIGSFLDKIGSKFGLFGNKAKEGTDKASNGARR
                     SGGIISQIFSGLGNIVKSAGTAISTAAKGIGAGIKTALSGIPPIISSLGTAISTVAQG
                     IGTGLAIAFKGLGAAIAMVPPTTWLALGAAVLMVGAAFALAGTQADGISQILRTVGDV
                     VVQILQQVTDSLATLLPIIANAIGSMLPIVAGAISQIVGAVAGGLSQLVIAVSTGASL
                     VIGAFTGLLGGISGVINSISAVIQSLTGVITAVFNGIATVISSVGSAIKDVLTGLGTA
                     FEGFGNGVKSALEGVGAVIESFGSAVRNVLDGVANILDSMGTAALNAGRGVKEMARGI
                     KMLVDLSLGDLVATLAAVASGLGKIAASAGQMTMLGSAMSKVANGMTHLATSATIAVA
                     GLTVFATTMATIKTAVATLPPVLTMAASGFTTFTTQAVAAVTGLTAINAPITMFKAQL
                     MTITPALAQAGAGFAAFVAQSSTFSTGLASAGPTIAAFNANLMSLSATTGVLVASIAG
                     LSAVLSVVSAGFSQIGASATATVGQIQAFASSTTVVSSAFASMQSMIQSAMAAIVSSI
                     ITSFNQAASQMQSILSRMLSQARTFGSQLEQQMRQSGQRSGQNLARGLSSQQGAVINA
                     ISSMVNAAVSRANAGAGPMRQAGAYIGQGLAQGMYSALGAVTAAANALVAQAERAARA
                     KAMIHSPSRLFAKRVGQYIPQGVAMGIDKNADVVDDSVGGLFDSINSFDFNIADRLAS
                     IGAKFQGVIKSESSQSLSQQQEFVHTAQPAYINFSLGGNEYEAFVSDITNQQAKIEKI
                     RLKRSSW"
     gene            17830..18609
                     /locus_tag="ACF4ZO_001385"
     CDS             17830..18609
                     /locus_tag="ACF4ZO_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="distal tail protein Dit"
                     /protein_id="HFD5486913.1"
                     /translation="MYEFNDTIRGTPKVTFNLKTTIGGKVLEDELNNGFGTFRTLTVS
                     GRDVVDLEHQTTSVLGRNGEYFHNATVEVRKLEIKAKISGKDNKSMRLQYEKLNKLIV
                     SHNQVFLSFSDEPDRNYLGIFKSKDVPEEVSNEQIIGLVFICYDPFKMSGIKTKKGDV
                     VQNDGLFNTKPIITLNLSSPTEEIKLLHVESQKYIRLTGTYTIDEIKIDMATGKITQN
                     GRNILGDLDMVNSRYFELRPGVNTLKCDNATITAEFREVYL"
     gene            18606..20657
                     /locus_tag="ACF4ZO_001386"
     CDS             18606..20657
                     /locus_tag="ACF4ZO_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail spike protein"
                     /protein_id="HFD5486914.1"
                     /translation="MIYLFDKLEQLIDTVGHQDLLSWHFKVKNNDWDQASFEVPIDYD
                     IEPFVYFGFFHKVPDEEREVFKLFKVIDYNLEDSKFYKGLDKAESDLDTIAIIKDKRF
                     RQSSADACLEDALVDTGYQVGKVEGISEVRTLSYYYISPRAALIKVVEAFNCEFNVRY
                     TFVNNKITSRYIDLKKRFGKPTGKQFEHGNNLLKVVYEESTDDIVTCLIGRGKGEEIQ
                     HEEAEPKDVEGHLPQEERWQGYGRRIEFTDVVWSVEKGDPIDKPAGQNFVALDSAREE
                     YGLSQNGELKHRWGVFVNEEIEDKTELLKATWEELQRLSIPIRIYKAEILDIGPETWK
                     GDSVAIIYDEVKIAFETRVDEIDIDKLNFNRSVVTLGDYSVVQNRESRSRKEAVQNMI
                     DESLETITDLGMTFQEFLQGIEKRIETGKKEMEDNWRKVNLEFDNFKKKVEQEGLQFN
                     TLKEQIKEVDERTDKELEEFRATLKNLTLPEEAIKKITEAIKVDDIPSLKQNFDDLKN
                     KVSETSETARLNAEIIGTDGKTRYNKNLLVGDPNRVKKIDEDYIEVEANDGGFKRGEI
                     YTISFSQTCELLKKVAVTLTQANNKGVKLVLTPTKAKMEPQTFNLTKDKEVISVYPLS
                     YTGVLTGDWYKSKSVEINASEGQNMALEMAYKDVVDGNNATIAGQWSDSPQMILDGGK
                     K"
     gene            20654..21679
                     /gene="hylP"
                     /locus_tag="ACF4ZO_001387"
     CDS             20654..21679
                     /gene="hylP"
                     /locus_tag="ACF4ZO_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronidase HylP"
                     /protein_id="HFD5486915.1"
                     /translation="MSENIPLRVQFKRMTASEWARSDVILLESEIGFETDTGFVRAGD
                     GHNRFSELGYISPLDYNLLTNKPNIDELATKVETAQKLQQKADKETVYTKAESKQELD
                     KKLNLKGGVMTGQLKFKPAATVAYSSSTGGAVNIDLSSSRGAGVVVYSNNDTSDGPLM
                     SLRTGKETFNQSALFVDYKGTTNAVNIAMRQPTTPNFSSALNITSGNENGSAMQIRGV
                     EKALGTLKITHENPSIKADYDKNAAALSIDIVKKQESGGKGTAAQGIYINSTSGTTGK
                     LLRIRNLNDDKFYVKPDGGFYAKETSQIDGNLKLKDPIANDHAATKAYVDGEVEKLKA
                     LLTAKQM"
     gene            21692..>21778
                     /locus_tag="ACF4ZO_001388"
     CDS             21692..>21778
                     /locus_tag="ACF4ZO_001388"
                     /inference="COORDINATES: protein motif:HMM:NF019517.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gp58-like family protein"
                     /protein_id="HFD5486916.1"
                     /translation="MSRDPTLTLDESNLVIGKDGRVHYTFTAE"
BASE COUNT         7329 a         3798 c         4927 g         5724 t
ORIGIN      
        1 aggtaatgga ggatagagaa tgacagacat caagatttta gatgcttgtt gtggaagtcg
       61 cctattttgg tttgataaaa acgaacctca cacaactttt atggacgtca gacaagaaaa
      121 atttgagatg cacggcaaaa aaatcaatgt caaccctgat gtaattggtg attttcgtga
      181 catgcctttt gaaagtaata gctttaacct tgttgtcttc gatccaccac acttaaaata
      241 tgttggacaa aactcaatta tgaaagccca gtatggtcaa cttgataaag aaaactggaa
      301 agaagatatt tcaaaaggtt tcgaagagtg tatgagagtt ctaaaagtag gaggaacttt
      361 agtttttaaa tggtctgatt gccaggttaa tgtaagagaa gttttgtcag caattccatt
      421 taaaccgctt tttggtcagc aaagaggcac tacacattgg atgacatttg ttaaatttga
      481 gcttactgga aatgggggat agtgatgtga aatgcgaatt gtataatgat cattttgaga
      541 acgctaaacg ttacaacata ccaagagcgc aattaattat tgcggatatt ccttataact
      601 taggcaataa tgcctatgcg agcgacccgc gttggtacga aaatggaagc aacaaaaatg
      661 gcgaaagtaa actagcaggt aaatcatttt ttgatacaga caatgatttt aaaatcaata
      721 atttctttga tttttgtagc cgtctcttac gaaaagagcc aaaggaaaaa ggaaaagcgc
      781 cagcaatgat tgtttttcac gcttggcagc agcgagagct ggtcattgca tgcggtaaaa
      841 aacacggttt caataatgcc tatccactat attttacaaa gaaatcaagt cctcaagtac
      901 taaaagctaa tatgaaaatt gttggtgctg tcgaggaggc aacggtttta tacagagata
      961 agttaccaaa attcaataac agtggagcta tgatccttaa tcatgcaccg tgggaaaagg
     1021 atagctctta tccagttatc cacccaacac agaaaccaat cccagtttta aaaagattaa
     1081 ttgagatttt cacagatcct gatgatgtgg ttattgatcc tgttgctgga agcggatcaa
     1141 caattcgtgc agcaatcgaa atgaatagaa atgcttatgg atttgaaata aaaaaagatt
     1201 tttataagag agcgaaggaa gaaatgctta gtacgtttca aaccagtctt ttttgaaaaa
     1261 ggaattcaaa ctgatattta taatttttta accgaggtac aaaatgaaca ctaacgaaaa
     1321 agtaatcgat actatatgtc acatcagaca ctacggtgac agatacgata tgtgccaaga
     1381 catgcggtcg tgggtagctg agagaaatgg attaatccag gacttactca aagcaaaaaa
     1441 acaaattgat cgcaatcgta tcgctaaacg tctggatcgt gcgcaaaaaa acatcagtga
     1501 cattatcaca aaagtgacag gcgacttatg gcaaggcagt gatcaagtca ttgctgagca
     1561 gtgtttttta aaagtattag aggagatgca aaaatgaaca ttgaagaagc gaaaagagcg
     1621 ataagagaac tagacgcaag cgctcaagag cctagtctga ccgacattga tgtcggtcag
     1681 ttgagcaatt aaattcccac gcaagcgctc aagagcctgc aatggctctg tgggggtgga
     1741 ccgaaattaa aaaatagaaa cgaggacctc cttacaccaa aacaaatcta acgcagatta
     1801 tcggtcattt gttattattc aaggcgctaa tactgacatc gtacgcctgt gtcgaaaaac
     1861 aaaaaaagaa agagaggact tttctccaca aaaaaagacg tccatgcgaa cgccttcatg
     1921 attaaatacc caacaatatt atatcatgaa tggagagtta gatgggcaac attccgacac
     1981 caaaagctaa taattttttg gaagaattaa agactatccc acatctcata gagacccttg
     2041 aaagagacgc taacctaatg agtcggtcgc tcgttaagtc tcctcaatgg tctgatatgc
     2101 gagtgtctgg tggggttaaa caatcacagg aagacaaaaa cataaagatg ctgcatatgg
     2161 ttagctatta tagtgatcag attgagcgtt taaaagaccg tcgacaagaa atggctaatt
     2221 tgattgtgca aagcatgggc atttgtgaga gtcacgtttt actcacgact tatcttgact
     2281 gtgatggaga ctatgagaga gccagagaac gcttaaacat aggaaatcgt aataaatact
     2341 ttatgtttgt taggcgagga aaggaaagtc tggaattgat actaaaaaat actaattaga
     2401 tacaaattga tactacataa tactaatagc tgtgttaata ttgtagtatg tgggacgtgc
     2461 aggttcgaat cctgccgtct caatcaccca gagattacac gctgtgacat tgcggaatgt
     2521 aatcaaagca aaaagaatca cggaactttg cgatgtccac cgtgaattaa cacccttatt
     2581 tgacattggc gttcctttga ggagaatacg caatctgggt tcggtgttaa tgattaagac
     2641 ttagcaacgc ctcttaacat gcgtaccagc gctaagtcga ttgattaacc gcaagtaaaa
     2701 caagggtcgc aaccttgctt gtggttagct gatagttcgg ttgaggattc ggccgaagtg
     2761 agttgttgca ctgtgcacgg tgtgataagc tatcgtgggc ttaagttttg tggcgaaacg
     2821 gcaccgttaa taatatttag actgtttatt tggacttgcg ttcgcattag gaaatactca
     2881 ctaaatattg agtgcagtgg cacgttcgat tcgtgcaagg tctgtagaag agcgtttgtg
     2941 agaggtctta gctcttctaa acctttggaa catgaaccgt gattggaaaa cggtggaggt
     3001 agcgccttgc ttcgggacgt tagctaagtc cgaaaactct ttgcgaagag ccagaagaag
     3061 atgtgtcggt tcgattccga ctgttcctgt aacaagttag cttaaagcgt aagtaattgg
     3121 tagacgtacc gaggaggggc gcatgcgcaa agcgctgggc tgataaccca gagatggagg
     3181 ttcgaatcct ctgcttgtgg taaaacagac cgacatagat gtcgggctga agtcacacaa
     3241 tcgtgtggct ttttattatg gattggaggt ggtggaaaat cgcatacgag gaattaaccg
     3301 aaaaacaaca gcgttttgtg gataagtaca tcaccacatt taacgctact gagtctgcaa
     3361 aacaagctgg atattctgaa aaaagcgctt atagccaagg tcaacgcttg ttgaaaaatg
     3421 ttgaaattca aaaagcaatg aaggaacgtt ttttggaggc aaaagatacc aaaggagacc
     3481 gtattcaaga tgttgcagaa acgttggaac aagatacatc gatagcccgt ggagaaatcc
     3541 aaatatctga attcaaagaa acagatatgc tgacaggtca agtggttatc cacacgaaaa
     3601 gagaatatac cccaagtcac gaagaacagg gtagggctag ggatagaatt tataaagtta
     3661 atggagctta ctcagaaaaa cgtgaattag agcattctgg aacggtggtg tttgcaaatg
     3721 aagacaacat ccctgattaa agtagatttg ccatcaacaa tcggtatagg ttatggcgct
     3781 ttttggcggt ctagaaattt ttatcgagta gttaaaggta gccgcggatc taaaaaatct
     3841 aaaacgactg ctttaaattt tatcgttaga ttgctgaagt atccgtgggc taacttattg
     3901 gtcatccgta gatactcaaa cactaacaaa cagtcaacct atacagattt taaatgggca
     3961 tgtaatcaat taaaggtttc gcatcttttt aaattcaatg agagtttgcc agaaataact
     4021 gtaaaggcaa cgggccaaaa gatactgttc cgtggacttg atgatgagtt aaaaatcaca
     4081 tctattactg tcgatgtcgg cgctttgtgc tgggcttggt ttgaagaggc ttaccagata
     4141 gagacagaag ataagttttc aacggtcgta gagtctatcc gcggtagttt agatgctcct
     4201 gattttttta aacaaataac agtcacattc aacccatggt cggaaagaca ttggcttaag
     4261 cgtgtctttt ttgatgaaga gacaaagcgg gatgatactt tttctgggac tacaacgttt
     4321 agagtcaatg aatggcttga tgatgttgat aaaaggcgct atgaagattt gtataagacc
     4381 aatccaagac gagctagaat cgtctgtgat ggcgaatggg gcgttgctga aggtcttgtt
     4441 tttgataatt ttgaagtcgt agattttgat gttgaaaaaa caattcaacg tgtcaaagag
     4501 acttcagctg gtatggactt tggttttact caagacccta caactcttat atgtgttgca
     4561 gttgacctcg taaacaaaga attatggctt tacaatgaac attatcaaaa agctatgttg
     4621 acagatcata ttgtcaaaat gataagagat aaaaatatgc ataaatctta tatcgcagct
     4681 gatagcgctg aaaaacgtct aatagcagag ataaaaagca aaggtgtatc tggtattgtt
     4741 gccagtctta agggtaaagg gtctattatg caaggagttc agtttatgca aggttttaaa
     4801 atatacatcc acccttcttg tgaacacaca atagaagagt ttaatactta cacttttaag
     4861 caagacaaag aaggtaattg gttaaacgaa ccgatagata agaataacca cgttattgat
     4921 gcgattagat atgcgcttga aaaataccat atcagaagca acgagtcaaa tcagtttgaa
     4981 gttcttaggg ctggttttgg ttactagaaa ggaaaataat gtacacagaa tcatttagag
     5041 atagtacggg aaagactaaa acattagagt ttaggttcca ccgtgaagct cgcatgaggt
     5101 atcaagcgga aagtctagaa agcttgttaa ccgaaaaata taagctactc cgtgaaatga
     5161 ttgagcacca cgataaagtc caaaaaccac gcatacaaga gcttttagat tatgcagagg
     5221 gaaataacca caccatcagc gaaataggcc gtaggaaaga cgatgacatg gctgatgttc
     5281 gtgctgtgca taactatggt aagtatattt caacgctcaa acagggctat ttggtgggta
     5341 atcctattcg tgtagagtat attgatggta ccgagcagca gcaagaccta ttaaaggacc
     5401 tatctgttaa aaacaatttc caccagctga accgcagatt agtaaaagac ctatccaagg
     5461 ttggtcgagc gtttgaattg atttatcgca gcatggatga caagacagag gtcgttagac
     5521 tagatccacg ggaagtattt gttatctatc aaaataacct agagcaatca agcttagctg
     5581 gtgtgcggta ctataacaaa aatcaattag atggtactac aaaaattgtc gagctttaca
     5641 ccgataataa aatcctgaag tttgaatatg atggtgattt aacacctatc ggagagattt
     5701 cctctcatgc gtttggttcg gtgccaatca cggagtacct caacacagat gacggcatgg
     5761 gtgactacga gacagagttg tctttaatcg acttgtatga tgcagcgcag tctgacacag
     5821 ctaactacat gcaggatttg tcagacgcga ttctggcaat cattggtcgt gtatcattcc
     5881 ctggctatgt cgacactgcc gaaaaagcca ttgaatactt acgtaagatg cgtaaagcta
     5941 gattacttaa cttagagcct cctgtcgacc aagacgggcg tgagggatct gtagatgcca
     6001 aatacttgta taaacagtat gatgtaaacg gtactgaggc atataaaaca cgtatcgtgt
     6061 cagatataca caagtttaca aacactccag atatgacgga tagcaaattt gcggggcaac
     6121 aatctggtga ggcgttgaaa tggaaggtgt ttggtcttga ccaggaacgt gtagatatgc
     6181 aagcgctgtt tgaacagtcg cttaaacgta gatataaact tatcgcacgt atcagtcaat
     6241 tgcttaaaga gattgatggt tttgatatta acaggcttaa aatcacattt acaccaaacc
     6301 tacctaagtc gctacaagaa aagattgaag cctttaaagc attgggtgga gagttgtcgc
     6361 aagagacagc tatggctatt acagacatcg tggaagatgc taagaaagaa attagcctta
     6421 tcaacagcga gtcgaaatca cgtagtcaac tagcgcagaa gttagaagaa accagtagat
     6481 tgactgatag ggagttagct catgaccacc agaaagagta aatactggcg tgaccgtatc
     6541 aagaaagaaa tggatgctaa agaggcagac gatatctctc ttgagcaatc catgaagcaa
     6601 ttgcacgatt atcatttcag gaatatcgaa aaagaaattg agtcgtttta tcaacgttat
     6661 gctgacaaag agaagataga cctttcagaa gcccgtaaga gagcttctga gcttgatatt
     6721 tctgcttacc agaagaaagc taaggaactt gttgcaaagg ctgagaagct acgaaaagag
     6781 ggaagaacgg taacaagaga tgactttacc caccaagaaa atgcagacat gtctatttac
     6841 aacttagcca tgaaaacgaa tgctttggag ctattgcgct taaacattga tttagaaatg
     6901 caagaacttg ccaacggcga acacaagcta accaagaaat ttcttgatga aggctatcgc
     6961 aaagaaaccg agtttcaagc tgggctatta ggattatcag ttgctagcca agcgagtgtg
     7021 aaaagcttag ctgatgccgt tatcaatgct aatttcaaag gagcaaaatg gtcagataac
     7081 atttgggaca gacaagataa gttacgcagt atcatatctc aaagtgttca gagtgctatc
     7141 ctaagaggta aaaatggctt aactattgca agggatatca gacgagagtt tgatgtgtca
     7201 gcatcttacg caaagcgact agcgataacg gagcatgcaa gggttcagat ggaagttggt
     7261 agattatcca tggcggagaa tggctttgct atgtttgata tattgcctga gcctaaagca
     7321 tgtgatgttt gcaaggatat agctaagcat ggtccatatc accttgacaa gtggagaata
     7381 gggggaaact ctccgccgtt tcatccgtat tgtcgttgtg cagttgtagg actggataag
     7441 aaacaagaag aaaaagtgaa tgataaatct gaaaaatttg aaaaacataa caccgaatct
     7501 catgccgtta tttagtaagt ttgcaagtaa aataacagat ttgcaacgta aaatagtgta
     7561 ctctgctgat ttagcagata ccgggtacat tagaacaccg catgcgtttg atataaacaa
     7621 taccttgcga aataaaggct acaattatct aaacgttgat gataaactaa ttaccgacac
     7681 attggatagt gtcatctcga taaattcaac tcccaaaaat ataaaagtat atcgctttga
     7741 tgactttgag ttattaggtt caatcaacga acaaaacaat aatatttttg attcaggtaa
     7801 ttttatggat aaattaaacc agggaggatt atcatacacc aacgatggat atacttctgc
     7861 aagttatgat gttaaaaaaa acgtgatggg atatcgtcct attaagactg aaataaaagt
     7921 acctaaagga agccacgttt atcttacaga taatgaggaa gaaagtgaaa ttatactacc
     7981 acgagggaca aagtatgata taattaatgc gaagataaat gaatatgaag aaatagaaat
     8041 cactatggaa ataagaaagg agtaagcgat ggatttttct gattttttga ataaaaaaca
     8101 aaaagagtgg gatgaatctc atccaattcc tgactttagt gcaatgagtg atgaagaatt
     8161 gctttatcag ccaatgagtg aagctttagt gtctgaaaga tttgctaaag agttatctaa
     8221 agaggttaga aagcgtaatt tattatcaaa ataaaaacat attattatag acggaagact
     8281 gtggtcgccc gtcttttttt gtacccaaaa acaggagaaa agcaatgaat aaacgactca
     8341 aaaagaaacg caaattggaa acagcagttg tgatattgat taaagaagtc gccgaattac
     8401 gatccatcgt gtcagcgaac gctcaagcga caaataacga gttagcgact gttaaggctg
     8461 ctactttaga cacccaatca gctatcaagt cgattggtga tgatgttgac tacattaaga
     8521 aaaattataa gcgcaagtgg ggtaagaaat gaaatatcgt aagaaacctg tcgaagttga
     8581 agcgtttcag tggtacggtg atattcgcca aaaagaagat ccagagtgga taattagcgc
     8641 gatttcggaa gaaagagctt ggattgaggt tgacaaggtt gttaacagtc ctgttttacg
     8701 tataaacact ttagagggtg ttatgacagc taatcaaggc gattacatca tcaaagacgt
     8761 agctggggaa ttttatccat gcaaacctga tatttttgaa cagacttatg aacctaatcc
     8821 aaagtcgtag taatacggct ttttattgtg ccctgagcat ggcctaaaaa ggctcaaatt
     8881 aatcactagc gtggcttgtg gataaatata cctaatagag actaggagac atgaggcgcc
     8941 cgttttcgtg gctctgtggt gtgtttaaaa acaggactag cgtgggagga aaaatgacta
     9001 aagaactatt agcaaaactt tttaaatgtg ctccagatac cggtacaggt tcagaagggg
     9061 tttctgacgt agataaccaa caaaacgaca cagatggtga atcatctagc ggtgatggct
     9121 ttaaggctcc gcaatctcaa tcagagttgg atagttacac aaataaagct attcaaaaag
     9181 ctttggaaaa tcagcgcaaa gacgaagcta agcgtattga tgacgctgtg aaaaatgctt
     9241 tagcaaaaga aaaagactat tccaaactat ccgaagaaga acgtcagcag cgtgaatttg
     9301 aagatagcaa aaaagccttt gaagccgaaa aagccaagtt tgaacacgat aaacttgtgg
     9361 tgcaagtcga aaaggatctt atcgccaagg ggctgccgtc tgaatttgct gaattgcttg
     9421 ctacaaaaga tgcagaagat gcactagagc aagcaaaaac atttgaagtg gcatttaaaa
     9481 aagcagtagc tgaagaagtt aaaaagaccg tgcgacaaga aaccccagca aacggcggtg
     9541 gattgagcaa acaaaccaat tacggtgcta acttggctag taaggcagca caacaaagca
     9601 ccaagctttt ttaggaggaa attatgaaca aacgtaaagt aataacatct aaagagattc
     9661 tacacaatct cgactatgag gctatttcag tcactttaga ttcagacgaa atcggcaaga
     9721 aagttgttcc agctgggaca gtgttagcag gtgtctcgga atcagtattt aaagatcgca
     9781 aacagaaagt taaagcggtc gatgacagtg cagactacat tgacggcatc ttacttacag
     9841 atgttgattt aacaaatggc gatgcagctg gttcttgtgt ctatcgtggg actattaatg
     9901 cagacaagct tgctgattca tctgttgcga aaaattatga gaatttggaa gaagtactac
     9961 cacacatcca atttatcaaa ggaggtaaat aaatatggcg ttaatccatg aaattatcac
    10021 atcggaaaat atcaaaggtt tttacaatgc taaaaacgaa aatgtcggaa acacgctagg
    10081 ggaaaatgcg tttccgccaa aacaacaact aggccttgaa ctgtcattta ttaaaggtgc
    10141 agcaggaaag ccggttactc ttaaagcagc tgcttttgac actaaagtgc cgctacgtga
    10201 tcgtatggct gttgaattgc ttaatgaaaa aatgccattc ttcaaagagg ctatggttgt
    10261 caaggaagca gaccgtcagc agctcagttt gttagctcaa actaaaaatc aagagcttat
    10321 tgacacagcg ctagcagcga tttacaacga taaagtaaca cttattgcag gtgcaaaagc
    10381 acgtctagaa gcaatgcgta tggaagtatt gtctaaaggt aaaatccatg ttgcatcaaa
    10441 cggtgtcatg aaagattttg attatgggtt agattcttcg caaacaacta agccagatac
    10501 aaaatgggaa caagcagata ccgctacacc acttaaagac atcgaaaaag ctatcgaagc
    10561 aatggcagaa cgtggctttg tgccagaagc tatcatcatg aactctaaga cacttagcct
    10621 gattaaaaat gcaagtaata ctttagacgt tgtaaagcct atggcgccag atggggcagc
    10681 tgttactaaa ggcgatttgg aaacttatat tgccgatgaa ctaggtctta aaattttgct
    10741 taaggatgga atgtttgtcg gagacgacgg taaagctaaa aaatacttcc cagatggatt
    10801 tgcaacttta gttcctaacg gcaatcttgg ttacacagta tttggtacta ctccagagca
    10861 atcagatttg cttggtggtg aggcaacaga tgctgaggtc tctattgttg aaacaggtat
    10921 tgcaattacc actactaaga caactgaccc agtgaacgtc caaacaaaag tttctatgat
    10981 tgctttgcca tcgtttgaac gcttggaaga agtacaaatc attaatgcaa cagaatccga
    11041 agaagaaact aaaaaagaaa acagctttga gatgtaggag gtcaacatgc ctagagtaat
    11101 tagagcattt aaagataaag taacaaaagt agtctacgaa gtcggcgata tttactcggg
    11161 cgaccgagta gagtttttga cagagggcgg tgttttagaa ccgtctgtag actttgacaa
    11221 gctaaaagtg agtgagatta aaagcaaact tgacgaacta aatgttgggt atgatgctaa
    11281 acttaaaaaa tccgagctat tgaagctttt aaagcaagca atcggatagt ttggaggtgt
    11341 ttatggatgc agtaaacaca agtagcgtta taagcaatgt aaagcttgat ttaggcatct
    11401 tagacagtca acaggacgat ttacttaaca tgttgctaaa acgcgttaca gaccatttta
    11461 aagctaaata tggcgttgtc aaaatagaca gcgcttttag ttttgtttta gaagattgtt
    11521 taattgctag atttaaccgt agaggtgcag aaagggcaaa aagtgagagt gtggaaggtc
    11581 atacgacgac atactacgac tttttggacg agtttgaacc atacgataac atgattatgg
    11641 caaagcttga cttaatcaag gacaaatctc gtaaaggggg actgtacttt ttatgagata
    11701 tgcagataga gttacgtttg ttaaaacgac agatgagcga tacgaccctg atttaggcga
    11761 gtacacgcac acagagacta taagcgagac aaaaccttgt tttgcgatgg aaatgggtgt
    11821 ggagaagtcc gtgcagattt ttggagatta tcaaaaggac cgtaaagtca tttacctaaa
    11881 acagccttac acaaaagcat ttgattattg tgagtatgag ggtaagagat acaaagcgca
    11941 ggcaaacaag cttggcgcta ttgtttttta tctggaagga gatgattcta ttggtagctg
    12001 atatatcttt aaaagtagtt ggaacagctg gtttaaaaaa taaacttgag cttattatca
    12061 aaaaagacgc tgtcaagaag attgtcaggg ataacggtaa tcagcttcaa aggaaaatga
    12121 ttaataaagc ggtatttaca aaaggttact caacaggtgc aaccagacgt tctattacca
    12181 tggaaatcgg cgatggtgga cttagtgtca cggttaaacc aggaactcat tatgctggct
    12241 accttgaaag aggaactcgc cttatggata aacaaccatt tgtgttgcca gctctaaaag
    12301 agcaaaaagt taagtttaga aaagatttgg aggcacttgt taaatgatta aaactagaga
    12361 tcagtctatt tttgatgaaa tgtacaagcg tatccaatcg ctaaactacg acgtttacga
    12421 ctataaacca ccgcttgaag tcccatatcc atttgtggaa atggaatcta ctgatgcgga
    12481 atatattcca aataaagacg acattaaagg ttcagttgaa cttacattgt ccgtttgggg
    12541 gttgcagaaa aaacggaagc aggtgtctga catggcatct gctatttttt cgcaagcttt
    12601 ggcagtggag agttctgaca gtttttactg gtcgtttaat agccgtcagt cgtctgttca
    12661 gattttggac gatacaacaa ctgtgacacc tcttaaacga gcgattgtca cacttagatt
    12721 taatttgaga taggaggtag taatgccaga acctagcaaa gaaacaacac aagaggaaga
    12781 aaatttaaga aaggaaaaag agatgacagc acaaacacaa ccaaaacaat tagaagcaaa
    12841 acaaggaatt cactcaatct tgttatttcg tttgttaaaa gaggcgtccg aaaaaccagc
    12901 gactaaactt gcttttcaaa cggaacacga agttggtaaa agtcgtgacg tcgacagcaa
    12961 aaagactaaa gatggtatta tccaatctgt gggagcttta gaatacgact ttaaagcaac
    13021 atctatttta gctaaaggtg atgagttagc agccaaacta gaagaagcca tggaaaaagg
    13081 tgagcttgta gaaatttggg atattgattc agaagaagca agcaaaaaaa acggttccaa
    13141 taaataccca gcgacttatt accaaggata catttcaagc ttcagtgcta agaaaaacgc
    13201 agaagaaaac attgaaattg aaatggaatt tgccatcaac ggtgttggtc agaaaggtga
    13261 cgctacatta acagatgccc aaaaagcagc tgtacagtac aattttaaag atacaacaaa
    13321 gtccaacggc gaagaaacta aaaaagaaaa cagttttgaa atgtaactgt taggctggat
    13381 ttagcatcca accttttatt ttaaaggaga aagaacaatg caattagaaa ttaaaggaaa
    13441 aactcataac gtaaaatttg gcacacgatt tgttgctgaa atggataaaa atcatgttac
    13501 agaacgtgat gggatgaaat tcggtactgg cttacaatca acggtcccat ttttgtttga
    13561 gcgtaatgtt gtgacacttg ccgaaatcat tcatgtcgga actattacag aatcacctcg
    13621 tccaagcttg aacgacattt acgactacat tgatgaagtc gatgatattg aaaaactctt
    13681 taatgatgtt ttagatgagt tacgtcagtc aaacgcttca aagttattta tggctcgagt
    13741 agagaaaaat ctagcagagg tagcagccga agcctaaaag aacccaatga acattattct
    13801 tctcaagaaa gctttgagat gattgtgctt aattgtatta gatatctcgg catgactgac
    13861 atcaatgaaa tcgggcgatt aactttgtat gaatatgatt tattaatgac aggcaaagca
    13921 ctagcggctg ttgatgaatc acataaagct cacaaacaag cttggataaa ccaccaagtt
    13981 acggcaacaa aacttgttgg tggcaagaaa aataaaaaag aagtccctgt ttataaaaaa
    14041 ttcaaggact tttttgatta tgaggaagag atccgaaaaa tcactcaaga aattgatgaa
    14101 ggttacgaca agaaaggtat ggatttactt ctcaaagcta acctttaaag aaaggaggtt
    14161 aaatgggaga atcttattct gttgaagcgg tattgaccgc tgttgataaa acctttggca
    14221 aaacattaca atcggcaatc cgttcaatcg atggcttgga aaagcgttca agaggctttt
    14281 caagcgtttc tcaacgagct gggtctatgt ttaaaaacat gcttggggct aacctagctg
    14341 gacaagctat ctcagcaatg acaaggacag tgtcatctgg tcttggctct atgcttggcg
    14401 aaatgaacag ttccgctaaa gcgtggaaaa cgtttgacgc caatttagcg gacattgggt
    14461 ttggaaaaaa acaaattttg gcagctaaaa cggcgatgca agactatgca actaaaacaa
    14521 tctactcggc atcagatatg gctagcacgt atgcacagtt agcagcagtt ggtgtgaaag
    14581 ataccggaaa gctcgtaaaa gcttttggcg ggttagctgc atctgctgaa aatccgaagc
    14641 aggccatgaa atcaattagt cagcaaatga cacaagctgt tggaagacca acagttgcat
    14701 ggcaagattt taggataatg ttggagcaag cacccgcggg tatggctaaa gtcgctaaat
    14761 ctatgggtaa aaatcttgat gaactcgtcg ctgatattca ggctggtaga gttaaaacca
    14821 gtgacttttt ggaggcggta aaaaaagcag gcaatgataa gagtttccaa aagatggcaa
    14881 ctgagttcaa aacggttgac caagctatcg acggtatgcg agaaggctta tccaacaaat
    14941 tgcaaccagc ttttgaaaaa gtgaatcaat ttggaatcag agcgtttaaa tctattgctg
    15001 agcaattgga taaagttgat ttttctcggt ttgctaataa catcgggaaa tttcttgaag
    15061 gaattaacat cgagaaggtt atttctaggg ttgcaacatc catttcgtct gtcgtttcga
    15121 aaatcaaaga attttgggac ggtttcaaac aaactggagc aattagtgct ttttcaggag
    15181 ctttaaaaag tgtttgggga gcgttaaaaa atgtagctag cgctatgagt ggaggcagtt
    15241 ggaaaaactt tggctctatt gtaggcggaa ttgtaaagca tgtgtctaat tttgcaaaag
    15301 ctattgctga tgttgtcggt aaaatggaac ctggcagatt gcaaagctgg atagccactt
    15361 ttgcagcagt cgggggaggc tttaaattat tcgaaaaatt aacgggacaa agcgtcattg
    15421 gttctttttt ggataaaatt ggcagcaaat ttggcctctt tggaaacaaa gccaaagaag
    15481 gaacagacaa agcctctaac ggcgctagaa gaagcggtgg cattattagc caaatcttca
    15541 gcggcttggg taatatcgtt aagtctgctg gtacagccat atcaacagct gcaaaaggta
    15601 tcggagctgg tattaaaact gctttgtctg gaatcccccc tatcattagt tctctaggaa
    15661 ccgcaatatc aacagttgcg caaggtatag gcactgggct agcgattgca ttcaagggac
    15721 ttggtgctgc gattgctatg gtaccgccta ccacatggct agctttagga gcggctgttt
    15781 taatggtagg agcagctttt gccttggcag gaactcaagc tgatggcatt agtcaaattt
    15841 taagaaccgt tggcgatgtt gttgtgcaaa tcttacaaca ggtcactgat agtctagcca
    15901 ctttactacc tattatcgca aacgctattg gctctatgtt gccaattgta gctggagcta
    15961 tctctcagat tgtaggcgca gtagcgggcg gattatctca gctcgttata gccgtttcaa
    16021 caggggcatc tctcgttata ggggctttca caggacttct tggtggtatt tctggggtta
    16081 ttaactccat tagtgctgtt atccaatcgc taactggtgt gattaccgca gtattcaatg
    16141 gcatagctac tgttatttca tctgtcggtt cggctatcaa agatgtattg acgggtctag
    16201 gaaccgcttt tgaaggattt ggaaatggtg taaaatcagc tctagaaggt gttggggcag
    16261 taattgaatc gtttggtagt gcagttagga atgtccttga cggtgttgca aatatccttg
    16321 attctatggg tactgcggca cttaatgcag gccgtggcgt aaaagagatg gctagaggca
    16381 ttaaaatgct tgttgacctg tcacttggag atctagttgc aacacttgca gcagtagcta
    16441 gtggacttgg aaaaatagca gcatcagctg gtcaaatgac catgttgggc tctgctatga
    16501 gcaaagtagc caacggaatg acacacctag caacaagtgc tactatagca gttgctggat
    16561 taacagtctt tgccaccacc atggcaacta ttaagacagc agttgcaact ctaccgccag
    16621 tcctaacgat ggcagcgagt gggtttacca catttactac tcaggcggtg gcagcagtga
    16681 ctggattgac tgcaattaat gctccaatca ctatgtttaa agctcaacta atgacaataa
    16741 caccagctct agcacaagct ggcgctggct ttgccgcgtt tgttgctcaa tcatcaacat
    16801 ttagtacagg tttagcatct gccggtccta caatagcagc attcaatgct aatttgatga
    16861 gcttatctgc aacaacagga gtgctagttg catcaatagc tggtttatca gctgtgcttt
    16921 ctgttgtatc agctggcttt agccaaatag gggcttctgc gacagcaact gttggtcaaa
    16981 tacaagcttt tgcttctagt acaacagttg tttcgtcagc atttgctagc atgcaatcta
    17041 tgattcaatc tgccatggct gcaatagtaa gcagcattat aacatcattt aatcaagcgg
    17101 cctctcaaat gcaatcaatc ttatctcgaa tgctatctca ggctaggaca tttgggtctc
    17161 aactagagca acaaatgaga caatcgggac agcgttcagg acaaaatctt gctcgggggc
    17221 tatcttctca acaaggtgct gttattaatg ctatttctag catggttaat gctgcggtat
    17281 caagagccaa cgcgggagct ggtcctatgc gtcaagctgg agcgtacatc ggacaagggc
    17341 ttgcgcaagg aatgtattca gcgctaggag ctgtaacagc tgcagcaaac gcccttgtag
    17401 cacaagccga gagagcagca agagccaagg cgatgattca ttcgccgtca aggttgtttg
    17461 caaaacgagt tggacaatat atcccgcaag gggtagctat gggtatcgac aaaaacgctg
    17521 atgtcgttga cgactctgtt ggcgggttat ttgatagcat caatagcttt gattttaata
    17581 tcgcagatag actggctagc attggagcta aattccaagg tgttatcaaa tcagagagtt
    17641 cacaatcgtt atcgcagcaa caagagttcg tacatacagc tcaaccagcg tatataaact
    17701 ttagtttagg cggaaacgaa tacgaagcat ttgtaagtga catcactaat caacaagcaa
    17761 aaattgaaaa aatcagacta aagagaagca gctggtagtt gtttctctta gttttttgaa
    17821 aggagtaaaa tgtacgaatt taacgatact atcagaggta ctccgaaagt tacttttaat
    17881 ttaaagacaa caattggtgg aaaggtatta gaagacgaac tcaataatgg tttcggtacc
    17941 tttaggacat tgactgtttc tggtcgtgat gtggtggact tagaacatca aacaacaagt
    18001 gtgttaggac gaaacggaga gtatttccac aatgccacag ttgaagtcag aaaactagaa
    18061 ataaaagcta aaatcagtgg aaaagataac aagtcaatgc gtttacaata tgaaaaatta
    18121 aacaaattaa ttgttagtca caatcaagtt tttttatcat tttcagacga acctgacaga
    18181 aattatctag gcatctttaa atctaaagat gtcccagaag aagtttctaa cgaacaaatt
    18241 attggcttgg tttttatctg ttatgatcca tttaaaatgt ctggtataaa aaccaaaaaa
    18301 ggggatgttg ttcaaaatga tggcttattc aatacaaaac ctatcatcac tctcaacctc
    18361 tcatcaccaa cagaagaaat caagctgcta catgtcgaaa gtcaaaagta tatcagactg
    18421 actggtactt ataccattga cgaaatcaag attgatatgg ccacaggtaa aattacccag
    18481 aacggccgca acatccttgg cgatttagat atggttaaca gtcgctattt tgaattgaga
    18541 ccaggtgtaa acaccttaaa atgtgacaat gccaccataa ctgcagagtt tagggaggtt
    18601 tatctatgat ttatctcttt gataaactgg agcaattaat tgatacagtt ggccatcagg
    18661 acttgctatc gtggcatttt aaggtcaaaa acaatgattg ggaccaagct agttttgaag
    18721 tgccaattga ctatgacatt gagccttttg tctactttgg ttttttccat aaagtcccag
    18781 acgaggaaag agaggtcttc aaacttttta aagttattga ttataaccta gaagacagta
    18841 aattttataa aggcttagac aaagctgaga gcgacctcga caccattgcc attatcaaag
    18901 acaagcgatt taggcaatcg tccgcagatg cttgtcttga agatgcttta gtggacacag
    18961 gctaccaagt tggtaaagtt gaaggaattt ctgaggttag aacacttagt tattactaca
    19021 tcagtccacg agcggctctg attaaggttg tagaagcttt taactgcgaa tttaatgtta
    19081 gatacacctt tgtcaataac aaaattacta gtcgctatat cgaccttaag aagcgttttg
    19141 gtaagccgac tggaaagcaa tttgaacatg gcaacaacct gctaaaagtc gtctacgagg
    19201 aatcaacaga tgacatcgta acctgcttga ttggccgagg caaaggcgag gaaatccaac
    19261 acgaagaagc tgagcctaaa gatgtcgagg gacacttgcc acaggaagaa aggtggcaag
    19321 gctacggtcg aagaatcgaa tttactgatg ttgtctggtc ggtcgaaaaa ggcgacccga
    19381 tagacaaacc agctggtcaa aactttgtag cactagatag tgcaagggaa gaatacggct
    19441 tgtctcaaaa tggtgagcta aaacaccgct ggggtgtctt tgtcaatgag gaaatcgagg
    19501 ataagacaga actcttaaaa gcaacttggg aagaattgca gcgtttgtca atccctatca
    19561 gaatttacaa ggcagaaatc ttagacattg gtccagagac gtggaaaggc gactcagtag
    19621 ccattatcta tgatgaggta aaaatagctt ttgaaactcg ggttgatgag attgatattg
    19681 acaagcttaa ttttaacagg tcagtcgtaa cacttggtga ttacagcgtt gtccaaaatc
    19741 gtgagtcacg gtctcgtaaa gaggctgtcc aaaacatgat agatgaatct ttagagacta
    19801 tcacagactt agggatgaca tttcaggaat ttttgcaagg catcgaaaaa cgcatcgaga
    19861 ctggcaaaaa ggagatggaa gacaattggc gcaaagttaa ccttgaattt gataacttta
    19921 aaaagaaggt tgagcaagaa ggcttgcaat tcaacacctt gaaagaacaa atcaaagaag
    19981 ttgatgaacg caccgataaa gagcttgaag agttccgagc caccctcaaa aacctaacgt
    20041 taccggaaga agccatcaaa aaaatcaccg aggctatcaa agttgatgac atcccgtctc
    20101 ttaagcaaaa ctttgatgac ttaaaaaaca aggtcagcga gacaagcgag acggcacgtc
    20161 taaatgccga gattatcggt acagacggta agacccgcta caacaaaaat ttattggttg
    20221 gcgaccctaa ccgtgttaaa aaaattgatg aggattacat cgaggtagaa gccaacgacg
    20281 gtggttttaa gcgtggcgag atctacacga ttagctttag ccagacttgt gagctactca
    20341 aaaaagtggc tgtcacgctg acacaggcta acaacaaggg agttaagtta gtgctgacac
    20401 caaccaaagc taagatggag ccacagactt ttaatctgac taaagataaa gaggttatca
    20461 gtgtttatcc tttgagctat acaggcgttt taacaggtga ttggtataaa tctaagtctg
    20521 ttgagataaa cgcctcagag gggcaaaata tggcccttga gatggcttat aaagatgtgg
    20581 ttgacggtaa taatgccacg atagcagggc agtggtcaga cagcccgcaa atgattttag
    20641 acggaggtaa aaaatgagtg aaaatatacc gctgcgagtc caatttaagc ggatgactgc
    20701 tagcgagtgg gctcgtagtg atgtcatctt actggagagt gagataggct ttgagacaga
    20761 cacaggtttt gtcagagcag gtgatggcca caatcgattt agtgaacttg gatacattag
    20821 cccactcgat tacaatctac tgactaacaa gccaaatatc gatgaattag cgacaaaagt
    20881 cgagaccgct cagaaactac aacaaaaagc agataaagag accgtctata caaaagctga
    20941 atcgaagcaa gagcttgaca agaaattaaa tctcaaaggt ggcgttatga caggtcaact
    21001 aaaatttaag ccggccgcca ctgttgctta ttcctcgtca acgggtgggg cggtcaatat
    21061 tgacttgtcg tctagcagag gtgctggtgt tgttgtctat tctaacaatg atactagtga
    21121 tgggccgtta atgagcttgc ggacgggtaa agagactttc aatcaatcgg cgctttttgt
    21181 cgattataag ggaacaacaa atgccgttaa tattgcgatg cgtcagccaa ccacccccaa
    21241 tttttcatcg gcgcttaata ttactagcgg caatgaaaat ggtagtgcga tgcaaattag
    21301 aggcgttgaa aaagcattgg gaacgctcaa aatcacacac gaaaacccaa gtattaaagc
    21361 ggattatgat aaaaatgcgg cagcgttatc tattgatatc gttaaaaaac aggaaagtgg
    21421 tggaaaaggt actgctgctc aaggaatcta cattaactca acatcaggta cgacagggaa
    21481 gttgcttagg attagaaacc ttaatgatga taagttctac gtcaagcctg acggtggttt
    21541 ttatgccaag gaaacttcgc agattgatgg caacctgaag ctcaaggatc ccatagcgaa
    21601 tgatcatgcg gcaaccaaag cttatgttga tggtgaagtc gaaaaattaa aagcactctt
    21661 aacggccaag caaatgtaaa aaggaggaga tatgagtaga gatccaacgt taacattaga
    21721 cgagtcaaat ctcgttattg gtaaggatgg acgtgtgcat tacacattta ccgcagag
//
LOCUS       DAXMQE010000031        21647 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.031, whole genome shotgun sequence.
ACCESSION   DAXMQE010000031 DAXMQE010000000
VERSION     DAXMQE010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21647)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21647)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21647
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.031"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            <1..969
                     /locus_tag="ACF4ZO_001389"
     CDS             <1..969
                     /locus_tag="ACF4ZO_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HFD5486917.1"
                     /translation="LASTINPFATGVAADAAGVSIADGMIWRVIQWVILVGMSIWFVY
                     NYASKIEEDPSKSLVADKEEEHKELFQLQNSGEDLNKRQRNVLTIFTLTFVIMILSLI
                     PWEDFGIKFFTNINTWLTTMPILGGVIGKTMGAFGTWYFPEITMLFIMMGILVAIVYR
                     MSEEDFFSSFLTGAGEFLGVAMICAIARGIQVIMNGGMITATILHLGETSLSGLSSQV
                     FVILAYIFYLPMSFLIPSTSGLAGATMGIMAPLGQFSNVPAHLVITAFQSASGILNMI
                     SPTSAIVMGALALGRVDLGTWWKFIGKFIVMVMLVSVLLLVVATFF"
     gene            986..2317
                     /locus_tag="ACF4ZO_001390"
     CDS             986..2317
                     /locus_tag="ACF4ZO_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HFD5486918.1"
                     /translation="MESYITPKHQEACVAAIKQIVSYPSVCHEGENGTPFGQAIQDVL
                     EATLDLCQGLGFHTYIDPKGYYGYAELGDQKEVLAILCHLDVVPEGDRQLWKTDPFDC
                     VEADGCLFGRGTQDDKGPTMMALFATKALIDAGVTFNKRIRFIFGTDEETLWRCMNRY
                     NDVEEQATFGFAPDSSFPLTYAEKGLLQAKLVGKGSDKLSLEIGQAYNVVPARASYQG
                     NKLEALQKELDKLGFEYVVKEGELTVYGLAQHAKDAPDGINAMIRLAKALVVLEPNKT
                     LDFLANVIDEDGRALNIFGRIEDEPSGKLSFNAAGLTLTKDKAEIRLDIRIPVLADKE
                     KLVQQLSQKAQEYGLTYEEFDYLAPLYVPLDSELVTTLLSVYRKKTGDQSPAQSSGGA
                     TFARTMKNCVAFGALFPDAVQTEHQENEHIVLADAYRAMDIYAEAIYRLTR"
     gene            2337..3287
                     /gene="arcC"
                     /locus_tag="ACF4ZO_001391"
     CDS             2337..3287
                     /gene="arcC"
                     /locus_tag="ACF4ZO_001391"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008804 - carbamate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HFD5486919.1"
                     /translation="MTKQKIVVALGGNAILSTDASAKAQQEALMSTSKSLVKLIKEGH
                     EVIVTHGNGPQVGNLLLQQAAADSEKNPAMPLDTCVAMTEGSIGFWLVNALDNELQAQ
                     GIQKEVAAVVTQVIVDAKDPAFENPTKPIGPFLTEEDAKKQMAESGASFKEDAGRGWR
                     KVVPSPKPVGIKEANVIRSLVDSGVVVVSAGGGGVPVVEDATSKSLTGVEAVIDKDFA
                     SQTLSGLVDADLFIVLTGVDNVYINFNKPDQAKLEEVTVSQMKEYITQDQFAPGSMLP
                     KVEAAIAFVENKPNAKAIITSLENIDNVLSANAGTQIIAG"
     gene            3600..4592
                     /gene="asnA"
                     /locus_tag="ACF4ZO_001392"
     CDS             3600..4592
                     /gene="asnA"
                     /locus_tag="ACF4ZO_001392"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004071 - aspartate-ammonia ligase
                     activity [Evidence IEA];
                     GO_process: GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HFD5486920.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLIAKLDVVEVQGPILSRVGDGM
                     QDNLSGTENPVSVNVLKIPNATFEVVHSLAKWKRHTLARFGFNEGEGLVVNMKALRPD
                     EDSLDQTHSVYVDQWDWEKVIPDGKRNLAYLKETVETIYKVIRLTELAVEARYDIEAV
                     LPKKITFIHTEELVAKYPDLTPKERENAITKEFGAVFLIGIGGGLPDGKPHDGRAPDY
                     DDWTTETENGYHGLNGDLLVWNDQLGSAFELSSMGIRVDEEALKRQVEMTGDQDRLAF
                     DWHKSLLNGLFPLTIGGGIGQSRMVMFLLRKKHIGEVQTSVWPQEVRDSYDNIL"
     gene            4715..5254
                     /gene="rsmD"
                     /locus_tag="ACF4ZO_001393"
     CDS             4715..5254
                     /gene="rsmD"
                     /locus_tag="ACF4ZO_001393"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052913 - 16S rRNA
                     (guanine(966)-N(2))-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HFD5486921.1"
                     /translation="MRVVSGEFGGRPLKTLDGKITRPTSDKVRGAIFNMIGPYFNGGR
                     VLDLFAGSGGLAIEAVSRGMSAAVLVEKNRKAQAIIQDNIIMTKAENRFTLLKMEAER
                     AIDCLTGRFDLVFLDPPYAKETIVATIEALAAKNLLSEQVMVVCETDKTVLLPKEIAT
                     LGIWKEKIYGISKVTVYVN"
     gene            5244..5735
                     /gene="coaD"
                     /locus_tag="ACF4ZO_001394"
     CDS             5244..5735
                     /gene="coaD"
                     /locus_tag="ACF4ZO_001394"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020905327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004595 - pantetheine-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HFD5486922.1"
                     /translation="MLTKIGLYTGSFDPVTNGHLDIVKRASGLFDQIYVGIFDNPTKK
                     SYFKLEVRKAMLTQALADFTNVIVVTSHERLAIDVAKELRVTHLIRGLRNATDFEYEE
                     NLEYFNHLLAPNIETVYLISRNKWQALSSSRVRELIHFQSSLEGLVPQSVIAQVEKMN
                     EKT"
     gene            5722..6759
                     /locus_tag="ACF4ZO_001395"
     CDS             5722..6759
                     /locus_tag="ACF4ZO_001395"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SepM family pheromone-processing serine
                     protease"
                     /protein_id="HFD5486923.1"
                     /translation="MKRLKKIKWWLVGLLALISLLLALFFPLPYYIEMPGGAYDIRTV
                     LQVNGKEDKRKGAYQFVAVGISRASLAQLLYAWLTPFTEISTAEDTTGGYSDADFLRI
                     NQFYMETSQNAAIYQALSLAGKPVTLDYKGVYVLDVNNESTFKGTLHLADTVTGVNGK
                     QFTSSAELIDYVSHLKLGDEVTVQFTSDNKPKKGVGRIIKLKNGKNGIGIALTDHTSV
                     NSEDTVIFSTKGVGGPSAGLMFTLDIYDQITKEDLRKGRTIAGTGTIGKDGEVGDIGG
                     AGLKVVAAAEAGADIFFVPNNPVDKEIKKVNPNAISNYEEAKRAAKRLKTKMKIVPVT
                     TVQEALVYLRK"
     gene            7175..8151
                     /locus_tag="ACF4ZO_001396"
                     /pseudo
     CDS             7175..8151
                     /locus_tag="ACF4ZO_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994809.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
     gene            8599..9219
                     /locus_tag="ACF4ZO_001397"
     CDS             8599..9219
                     /locus_tag="ACF4ZO_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HFD5486924.1"
                     /translation="MKKEISPEMYNYNKFPGPKFIHFEEQVKAEGIDLLLLEDVKNAF
                     DTTSFGQRYTEVLLKYDYIVGDWGNEQLRLKGFYKDSDDIKKTNRISRLEDYIKEFCN
                     FGCAYFVLENLHPQDIKFEEERQPRRKKSPKSKSNRRKPNYSNQQPATPKSKSKRVSK
                     EKQPENQAFTSQKRRSNTKHKEKSKRNQTSQLNTKISHFIIRKKDK"
     gene            9223..10302
                     /gene="rlmN"
                     /locus_tag="ACF4ZO_001398"
     CDS             9223..10302
                     /gene="rlmN"
                     /locus_tag="ACF4ZO_001398"
                     /EC_number="2.1.1.192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:0016433 - rRNA (adenine) methyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0030488 - tRNA methylation [Evidence IEA];
                     GO_process: GO:0070475 - rRNA base methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HFD5486925.1"
                     /translation="MKPSIYSLTRDELIAWAVERGQKQFRATQIWDWLYKKRVQSFEE
                     MTNISKDFVSILNDSFCVNPLKQRVVQESADGTVKYLFELPDGMLIETVLMRQHYGHS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNSGEITAQIMLVQKYFDDRKQGERVSHVVVM
                     GIGEPFDNYKNVMCFLRVINDDNGLAIGARHITVSTSGLAHKIRDFANEGVQVNLAVS
                     LHAPNNDLRSRIMRVNRSFPLEKLFSAIEYYIEKTNRRVTFEYIMLNEVNDSIKQAQE
                     LADLTKTIRKLSYVNLIPYNPVSEHDQYSRSPKERVLAFYDVLKKNGVNCVVRQEHGT
                     DIDAACGQLRSKTMKKDREKVTATK"
     gene            complement(10384..11010)
                     /locus_tag="ACF4ZO_001399"
     CDS             complement(10384..11010)
                     /locus_tag="ACF4ZO_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HFD5486926.1"
                     /translation="MIAFFSICSGILLTHLFYCLLLYFPDNGQEQLSKQTIIVCDQLT
                     FAKRVFRQFQNHFITSQKIFFSLEISLIIILWASMVHWVSASYCYLLLFSLLFSLFDW
                     RSQEYPFILWLFSFVSLLLFYSINYLSLILLLLGLLAHLRPFSIGAGDFFYLASLALV
                     LDLTSLIWLIQLASLAGITACLLLGIKRIPFIPYLSFGLFWIVLLEHF"
     gene            11238..11765
                     /locus_tag="ACF4ZO_001400"
     CDS             11238..11765
                     /locus_tag="ACF4ZO_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002264439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008199 - ferric iron binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Dps family protein"
                     /protein_id="HFD5486927.1"
                     /translation="MTNTLVENIYASVTHNISKKEASKNEKTKAVLNQAVADLSVAAS
                     IVHQVHWYMRGPGFLYLHPKMDELLDSLNANLDEMSERLITIGGAPYSTLAEFSKHSK
                     LDEAKGTYDKTVAQHLARLVEVYLYLSSLYQVGLDITDEEGDAGTNDLFTAAKTEAEK
                     TIWMLQAERGQGPAL"
     gene            11907..12110
                     /locus_tag="ACF4ZO_001401"
     CDS             11907..12110
                     /locus_tag="ACF4ZO_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HFD5486928.1"
                     /translation="MKTLYDVQQLLKNFGIFVYLGKRLYDIEMMKIELQRLYDSGLLD
                     KRDYLNAELILRREHRLELEKEG"
     gene            12115..13086
                     /locus_tag="ACF4ZO_001402"
     CDS             12115..13086
                     /locus_tag="ACF4ZO_001402"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004340 - glucokinase activity [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA];
                     GO_process: GO:0051156 - glucose 6-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HFD5486929.1"
                     /translation="MSQKLLGIDLGGTTIKFGILTAAGEVQEKWAIETNILEGGKHIV
                     PDIVASIKHRLDLYGLSSADFVGIGMGSPGAVDRDTNTVTGAFNLNWKETQEVGSVVE
                     KELGIPFAIDNDANVAALGERWVGAGENNPDVVFMTLGTGVGGGIIADGNLIHGVAGA
                     GGEIGHMIVEPENGFACTCGSHGCLETVASATGVVKVARLLAEAYEGDSAIKAAIDNG
                     EGVTSKDIFMAAEAGDSFADSVVEKVGYYLGLASANISNILNPDSVVIGGGVSAAGEF
                     LRSRIEKYFVTFTFPQVRYSTKIKIAELGNDAGIIGAASLARQFITK"
     gene            13096..13485
                     /locus_tag="ACF4ZO_001403"
     CDS             13096..13485
                     /locus_tag="ACF4ZO_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HFD5486930.1"
                     /translation="MSPITLILWLLLVGIVGYYTWNYFSFRKMAKQVDNETFKDVMRQ
                     GQLIDLREPAAFRAKHILGARNFPAQQFDAAIKGLRKDKPVLIYENMRPQYRVPAVKK
                     LKKAGFEDVYVLKDGIDYWDGKVKQTT"
     gene            13668..15509
                     /gene="typA"
                     /locus_tag="ACF4ZO_001404"
     CDS             13668..15509
                     /gene="typA"
                     /locus_tag="ACF4ZO_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018366892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HFD5486931.1"
                     /translation="MTNLRNDIRNVAIIAHVDHGKTTLVDELLKQSHTLDERKELQER
                     AMDSNDLEKERGITILAKNTAVAYNDVRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQNLIPIVVVNKIDKPSARPAEVVDEVLELFIELGADDEQ
                     LEFPVVYASAINGTSSLSDDPADQEHTMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDCVEALPILRIDEPTLQMTFLVNNSPFAGREGKWITSR
                     KVEERLLAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IIKEIDGVKCEPFERVQIDTPEEYQGAIIQSLSERKGDMLDMQMVGNGQTRLIFLIPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPVVQGEIGGRHRGALVSIENGKATTYSIMR
                     IEERGTIFVNPGTEVYEGMIVGENSRDNDLGVNITTAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAARDKANKKKKSAE"
     gene            15631..15882
                     /locus_tag="ACF4ZO_001405"
     CDS             15631..15882
                     /locus_tag="ACF4ZO_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HFD5486932.1"
                     /translation="MFYLIMAVLIISYYLYMAPKSVRNTLGMIGLVGLVALLIVLAGL
                     SFIKIMQTPPEFFIGMGMMALGYFALKDVRKMTKKPRVK"
     gene            16238..17596
                     /gene="murD"
                     /locus_tag="ACF4ZO_001406"
     CDS             16238..17596
                     /gene="murD"
                     /locus_tag="ACF4ZO_001406"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008764 -
                     UDP-N-acetylmuramoylalanine-D-glutamate ligase activity
                     [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HFD5486933.1"
                     /translation="MKVISNFQNKKILILGLAKSGEAAAKLLTKLGALVTVNDSKPFD
                     QNPAAQALLEEGIKVICGSHPVELLDENFEYMVKNPGIPYDNPMVKRALAKEIPILTE
                     VELAYFVSEAPIIGITGSNGKTTTTTMIADVLNAGGQSALLSGNIGYPASKVVQKAIA
                     GDTLVMELSSFQLVGVNAFRPHIAVITNLMPTHLDYHGSFEDYVAAKWMIQAQMTESD
                     YLILNANQEISATLAKTTKATVIPFSTQKVVDGAYLNDGILYFKEQAIIAATDLGVPG
                     SHNIENALATIAVAKLSGIADDIIAQCLSHFGGVKHRLQRVGQIKDITFYNDSKSTNI
                     LATQKALSGFDNSRLILIAGGLDRGNEFDDLVPDLLGLKQMIILGESAERMKRAANKA
                     EVSYLEARNVAEATELAFKLAQTGDTILLSPANASWDMYPNFEVRGDEFLATFDCLRG
                     DA"
     gene            17596..18678
                     /locus_tag="ACF4ZO_001407"
     CDS             17596..18678
                     /locus_tag="ACF4ZO_001407"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0050511 -
                     undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase activity [Evidence
                     IEA];
                     GO_function: GO:0051991 -
                     UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-
                     glutamyl-meso-2,
                     6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol
                     4-beta-N-acetylglucosaminlytransferase activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0007049 - cell cycle [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0030259 - lipid glycosylation [Evidence
                     IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HFD5486934.1"
                     /translation="MPKKILFTGGGTVGHVTLNLILIPKFIKDGWEVHYIGDKNGIEH
                     TEIEKSGLDVTFHAIATGKLRRYFSWQNLADVFKVALGLLQSLFIVAKLRPQALFSKG
                     GFVSVPPVVAAKLLGKPVFIHESDRSMGLANKIAYKFATTVYTTFEQEDQLSKVKHLG
                     AVTKVFKDANQIPESTQLEAVNEYFSRDLKTLLFIGGSAGAHVFNQFISDHPELKQRY
                     NIINITGDPHLNELSSHLYRVDYVTDLYQPLMAMADLVVTRGGSNTLFELLAMAKLHL
                     IVPLGKEASRGDQLENATYFEKRGYAKQLQEPDLTLHNFDQAMADLFEHQADYEATML
                     ATKEIQSPDFFYDLLRADISSAIKEK"
     gene            18679..19827
                     /locus_tag="ACF4ZO_001408"
     CDS             18679..19827
                     /locus_tag="ACF4ZO_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ/DivIB"
                     /protein_id="HFD5486935.1"
                     /translation="MAKDKEKQSDDKLVLTEWQKRNIEFLKKKKQQAEEEKKLKEKLL
                     SDKKAQQQAQNASEAVELKTDEKTDSQEIESETTSKPKKPKKVRQPKEKSATQIAFQK
                     SLPVLLGALLLMAVSIFMITPYSKKKEFSVRGNHQTNLDELIKASKVKTSDYWLTLLT
                     SPGQYERPILHTIPWVKSVHLSYQFPNHFLFNVIEFEIIAYAQVENGFQPILENGKRV
                     DKVRASELPKSFLILNLKDEKAIQQLVKQLTTLPKKLVKNIKSVSLANSKTTADLLLI
                     EMHDGNVVRVPQSQLTLKLPYYQKLKKKLENDSIVDMEVGIYTTTQEIENQPEVPLTP
                     EQNAADKEGDKPGEHQEQTDNDSETPANQSSPQQAPPSPETVLEQAHG"
     gene            20039..21403
                     /gene="ftsA"
                     /locus_tag="ACF4ZO_001409"
     CDS             20039..21403
                     /gene="ftsA"
                     /locus_tag="ACF4ZO_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0043093 - FtsZ-dependent cytokinesis
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HFD5486936.1"
                     /translation="MARNGFFTGLDIGTSSIKVLVAEFISGEMNVIGVSNVPSTGVKD
                     GIIIDIEAAATAIKTAVEQAEEKAGMTIEKVNVGLPANLLQIEPTQGMIPVPSESKEI
                     KDEDVDSVVKSALTKSITPEREVISLVPEEFIVDGFQGIRDPRGMMGIRLEMRGLIYT
                     GPSTILHNLRKTVERAGIKVENIIISPLAMAKTILNEGEREFGATVIDMGGGQTTVAS
                     MRAQELQYTNIYAEGGEYITKDISKVLKTSLAIAEALKFNFGQAEISEASITETVKVD
                     VVGSEEPVEVTERYLSEIISARIRHILDRVKQDLERGRLLDLPGGIVLIGGGAIMPGV
                     VEIAQEIFGVTVKLHVPNQVGIRNPMFSNVISLVEYVGMMSEVDVLAQTAVSGEELLR
                     RKPIDFSGQESYLPDYDDSRRPESTIGYEQQASQTAYDSQVPSDPKQKISERVRGIFG
                     SMFD"
     gene            21427..>21647
                     /locus_tag="ACF4ZO_001410"
     CDS             21427..>21647
                     /locus_tag="ACF4ZO_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HFD5486937.1"
                     /translation="MAFSFDTASIQGAIIKVIGVGGGGGNAINRMIDEGVAGVEFIAA
                     NTDIQALSSSKAETVIQLGPKLTRGLGAGG"
BASE COUNT         6983 a         3722 c         4551 g         6391 t
ORIGIN      
        1 ctagcctcca ctattaaccc atttgcaact ggtgtagcag ctgatgctgc tggtgtcagc
       61 attgcagatg gaatgatttg gcgtgttatc caatgggtta ttcttgtcgg catgtctatt
      121 tggtttgttt acaattacgc tagtaagatt gaagaagacc caagtaaatc attggttgca
      181 gacaaggaag aagagcataa ggaactcttc cagttgcaaa attctggaga agacttaaac
      241 aaacgccaac gaaacgtttt gaccattttt actttgacct ttgtcattat gattcttagt
      301 ttgattccat gggaagattt tggcatcaaa ttctttacta atatcaatac ttggttaacc
      361 acaatgccta tcttaggggg agttattggg aaaaccatgg gagcatttgg tacttggtat
      421 ttcccagaaa tcaccatgct ctttatcatg atgggtatct tagttgctat tgtttatcgt
      481 atgagtgaag aagacttttt tagctctttt ttgactggtg caggtgaatt tttaggtgtt
      541 gccatgatct gtgctattgc acgcggtatt caagttatca tgaatggtgg tatgattaca
      601 gccactatct tacacttagg tgaaacaagt ctttctggtt tatcttctca agtttttgtg
      661 atattagctt atattttcta cctcccaatg tccttcttga ttccatcaac atcaggactt
      721 gctggggcta caatggggat tatggcaccg cttggacaat tctcaaatgt ccctgctcac
      781 cttgttatta cagccttcca gtcagcttct ggaatcttaa acatgatttc tccaacttca
      841 gcaatcgtta tgggagcact tgcgcttggt cgcgttgacc ttggtacttg gtggaaattc
      901 attggtaaat ttattgtaat ggtgatgctt gtaagcgtgc tattacttgt agttgcaaca
      961 ttcttttaac agataggagg ttcctatgga atcctatatc acacctaaac atcaagaggc
     1021 ctgtgtagct gccattaaac agatcgtttc ttacccttct gtttgtcatg aaggagaaaa
     1081 tggcacacct tttggacagg ccattcaaga tgttctcgaa gcaaccttag acttatgtca
     1141 aggtcttggt ttccatactt atattgatcc taaaggttac tatggttatg ctgagttagg
     1201 tgaccaaaaa gaggtcttgg ctattctttg ccatttggac gttgttccag aaggagatcg
     1261 tcagttatgg aagacagatc cttttgactg tgttgaggca gacggctgtt tatttggtcg
     1321 aggcactcaa gacgataaag ggcctactat gatggcacta tttgccacca aagccttgat
     1381 agatgcaggc gttaccttta ataaacgcat tcgttttatt ttcggaacag atgaagaaac
     1441 tttgtggcgg tgtatgaatc gctacaatga tgtagaagaa caggctacct ttgggtttgc
     1501 tcctgattca agtttccctt taacctatgc cgaaaaaggc ctacttcagg caaaattagt
     1561 ggggaaaggt tctgataaac tgtcacttga aatcggacaa gcctacaatg ttgttcctgc
     1621 aagagcctct tatcaaggca ataagcttga ggctttacaa aaagaactag ataagcttgg
     1681 ctttgagtac gtcgtcaaag agggagaatt aacggtttat ggtcttgccc aacatgctaa
     1741 agatgctccc gatggcatca acgctatgat taggcttgcc aaagccttag tggtccttga
     1801 acctaacaaa acccttgatt ttcttgctaa tgtcattgat gaagatggca gagcacttaa
     1861 tatttttggc agaatcgaag atgaaccttc aggcaaatta agctttaatg ccgcagggct
     1921 taccttaacc aaagacaagg cagaaattcg cctagatatt cggattccag ttttggcaga
     1981 taaggaaaaa ttagtccaac aattaagcca aaaagcacaa gaatacggcc taacctatga
     2041 agaatttgat tatttggccc cattatatgt gccattagac agtgaattgg taacaacctt
     2101 gttatctgtc tatcggaaaa aaacaggtga tcaaagccct gcccaatcat caggaggggc
     2161 aacctttgct agaacaatga agaattgtgt tgcctttggt gctcttttcc ctgatgctgt
     2221 tcaaacggaa caccaagaaa atgaacatat tgttttagcg gatgcttacc gcgctatgga
     2281 tatttatgcg gaagctattt accgactaac gcgataacaa gatatgagga gtaattatga
     2341 cgaaacaaaa aatcgtagtc gcacttggag gaaatgctat tctttcaaca gatgcgtcag
     2401 caaaagcaca acaagaagcc ttgatgtcaa catcaaaatc actggttaaa ttaatcaaag
     2461 aaggtcatga agtcatcgtg acccacggca atggcccaca agttggtaat ctcttgttac
     2521 aacaagcagc agcagattct gaaaagaatc cggctatgcc tttggatact tgtgttgcca
     2581 tgacagaagg tagcatcggt ttttggttag ttaatgccct tgataatgag ttgcaagccc
     2641 aaggtattca aaaagaagtg gcagctgttg tcactcaagt gatcgtggat gccaaagacc
     2701 cagcttttga aaacccaaca aaaccaattg gtccatttct taccgaagaa gatgccaaaa
     2761 aacaaatggc ggagtctggt gcaagtttca aagaagatgc aggtcgtggc tggcgtaagg
     2821 ttgtgccatc accaaaacca gttggtatta aagaagccaa tgtcatcaga agtctggttg
     2881 attctggcgt tgttgtggtt agtgctggtg gtggcggtgt gcctgttgtg gaagatgcta
     2941 ctagcaagtc ccttactggt gtggaagccg ttattgacaa ggactttgct agccaaaccc
     3001 tttcaggatt ggtggatgca gacctcttta tcgttttgac aggagttgac aatgtttaca
     3061 tcaacttcaa caaacctgac caagccaaat tggaagaagt gactgtctct caaatgaaag
     3121 aatacatcac acaagaccaa tttgcaccag gtagtatgtt accaaaagtg gaagctgcca
     3181 ttgcttttgt tgaaaacaaa ccaaatgcta aagccattat cacatcgctc gaaaatattg
     3241 acaatgtact atcagcaaac gctggaacac aaattatcgc agggtaatca agaggatttt
     3301 tagttctgtc taaaagactc atttaatggt attttctgaa gagtacgact gacataaaga
     3361 gttgatactg tttttaaagg aaaagagtgt gccataataa aaaacaataa tagtattaga
     3421 aaaggctaat tttattgaga attagccttt tcttttggct ttgataggtg tataataacc
     3481 atactatttt ttatttttca aaatattaga ataaacaaaa gtagacaacg tataaagaga
     3541 actgctaagt cgttgagttc attagtccca aaaagattac caaaaaagaa ggaagaatta
     3601 tgaagaaaag ttttattcat caacaagagg agatttcctt tgttaaaaat acgttcactc
     3661 agtatttaat tgctaagtta gatgttgttg aagtgcaagg acccatttta agtcgggtcg
     3721 gggatggtat gcaagataat ttgtccggta ctgaaaatcc agtatctgtc aatgtcttga
     3781 aaattcctaa tgcaaccttt gaagttgtgc attcattagc aaaatggaaa cgtcacacct
     3841 tagcccgttt tgggtttaat gaaggtgaag gtcttgttgt taatatgaag gctctccgac
     3901 cggatgaaga ttcacttgac caaacccatt ctgtctatgt tgaccaatgg gactgggaaa
     3961 aagtcatccc tgatggcaaa cgtaatctcg cttaccttaa agaaaccgtt gaaaccattt
     4021 acaaggtcat tcggctaact gaattagctg tagaagctcg ttatgatatt gaggctgttt
     4081 tacctaagaa aataaccttc attcataccg aagaattggt agctaaatac cctgatttga
     4141 cgcccaaaga acgtgaaaat gccattacta aagaatttgg agcagtcttt ttaattggta
     4201 ttggcggggg tttacctgac ggtaaaccac acgatggccg cgctcctgac tatgatgact
     4261 ggacaacaga aactgaaaat ggctatcatg ggcttaatgg tgatcttttg gtttggaatg
     4321 accaacttgg ttcagccttt gaattatcct caatggggat ccgtgtggat gaagaggccc
     4381 taaaacgtca ggtggaaatg actggtgacc aagaccgctt agcctttgat tggcacaaat
     4441 ctttgttgaa tggacttttc cctctaacga ttggtggagg aatcggtcaa tcacgtatgg
     4501 tcatgttttt gttgcgtaaa aaacatattg gagaagttca gacctccgtt tggccccaag
     4561 aagttcgtga tagctacgat aatattttat aagtaatcac atcattttgc taagttttcc
     4621 acttatataa gagactttaa ataaatgatc agaaatattg aaaaaagaaa tcatttttaa
     4681 ggtttagagc tagaaatttg ctataataaa tgttatgaga gttgtatcag gtgaatttgg
     4741 tgggcgtcct ttaaagacgc tcgatggaaa gataacacgc cctacttcag acaaagttag
     4801 aggtgcgatt tttaatatga taggacctta ctttaatggt ggtcgtgttt tagatttgtt
     4861 tgcaggttca ggtggattag ccattgaggc tgtttctcgt gggatgtctg ctgcagtttt
     4921 ggttgagaag aatcgtaaag cgcaagctat tattcaagac aatattataa tgactaaagc
     4981 tgagaatcgg tttaccttgt taaaaatgga agctgagcga gctattgatt gcttgactgg
     5041 tcgatttgac ttagtctttt tagaccctcc ttatgccaaa gaaacaattg tggcaactat
     5101 tgaagcttta gcagctaaaa acttattgag tgaacaggtt atggttgtct gtgagacaga
     5161 taaaacagtc ttgttgccaa aagagattgc aacgttaggt atttggaaag aaaaaattta
     5221 tggaattagt aaggtaacag tttatgttaa ctaaaatagg actttataca gggtcatttg
     5281 atcctgttac aaacggtcat ctcgatattg ttaaacgggc aagtggccta tttgatcaaa
     5341 tatatgttgg gatttttgat aatcctacca aaaaaagcta ttttaaacta gaagttcgta
     5401 aagcaatgct tactcaagct ctggctgatt ttacaaatgt aattgtagta acttcgcacg
     5461 aacgtttagc tattgatgta gctaaagaat tacgagtaac tcacttgatt agaggcttgc
     5521 gaaatgcaac tgactttgag tatgaagaaa atttggaata ttttaatcac cttttagctc
     5581 caaatattga gaccgtctat ttgatatcaa gaaataaatg gcaggccctt agctctagtc
     5641 gtgtgagaga gctaattcat tttcagtctt ccttagaagg tttggttcct cagtcagtta
     5701 ttgctcaagt ggagaaaatg aatgaaaaga cttaaaaaaa tcaaatggtg gttagtgggt
     5761 ctgctagctt taatctcttt gttgctagcg ttattttttc cgctacctta ttatattgaa
     5821 atgcctggag gcgcttacga tattcggact gtcttacaag tcaatggcaa agaagacaaa
     5881 cgaaaaggag cttaccagtt tgttgcagtg ggcattagtc gtgccagcct cgcgcagcta
     5941 ttatatgctt ggctgacacc gtttactgaa attagtacag cagaagatac aacaggcgga
     6001 tacagcgatg ctgatttcct tcgaattaat caattttaca tggaaacatc acaaaatgca
     6061 gctatttatc aagctttatc cttagctgga aaaccagtta cattagatta taaaggcgta
     6121 tatgttttag acgtaaacaa cgaatctact tttaaaggaa cgttacactt agcagatact
     6181 gtaacaggtg taaatggtaa acagtttact agttcagcag aacttattga ctatgtttct
     6241 cacctaaaac taggggatga agttacggtt cagtttacga gtgataataa gcctaaaaaa
     6301 ggagttggcc gtattatcaa actgaaaaat gggaaaaatg ggattggcat tgccttgact
     6361 gatcatacaa gtgtcaattc agaagacaca gtgatcttta gtactaaagg agtaggagga
     6421 cctagtgctg gtctaatgtt tactcttgat atatatgatc aaataactaa agaagattta
     6481 cgcaagggcc gtacaattgc aggtacagga actattggca aggatggcga agtaggagat
     6541 attggtggtg caggtcttaa agtagttgca gcagctgaag ctggtgcaga tatatttttt
     6601 gttccgaata atcctgttga taaggaaatt aaaaaagtta atccaaatgc tataagtaat
     6661 tacgaagaag ccaaacgggc agccaaacga ctaaagacca aaatgaagat tgttcctgtt
     6721 acgactgttc aagaggcact ggtttatctt cgcaaataaa ataactatga atgtaattat
     6781 attcaattat attcacgcta ttaactcata aaaaaacggt tgaaccagat agacagttcc
     6841 ttgaccagtc ttttgggttc aatcattttt tacataaaac atatctaact tgacagcgta
     6901 aaaaagatgt tataaaagtc tagtggtaaa aaggcaatag agaattgagt aaactttagt
     6961 cgattatctg gaaatagagc atactaaaaa cacctagtga aaattgattt ttttcactag
     7021 ctcatccaag aacttgcgca gataatcatg agtccattcc atgactttat tattctggaa
     7081 agccttgcaa tagacaagtt aacgttataa caactaaatt aaaaacttaa gattgaaaaa
     7141 tccccataaa cttattttac aaggaggtaa ggctatggta actattaaac aagttgctga
     7201 agaagcaggt gtttctagat caacagtctc caggtatatt tctcaaaaag gatatgtatc
     7261 tgatgatgca aggcataaaa tcaaagcagc gatagcaaaa ttacattaca ctccaaatgt
     7321 cttggcgcag tcattgaaga cgaaaaaaat caactagtcg gtttattatt accagacatt
     7381 tccaatcctt tttttccgag gttagcaagg ggagcagaag aatatttaaa agaaaagggg
     7441 tatagggtta tgctaggaaa tatttcagac agcgaagctc ttgaagaaga atacgtccat
     7501 gtccttcttc aaagcaatgc tgctggcatt attactactc atgactttac aaagcggtat
     7561 cctactcttg ctattccagt tgtagtggta gatcgtgttg accaagagac ccagtacggt
     7621 gtcttttcag ataatagggc agggggctta ttggcggctc agactgtctg gcaagcaggg
     7681 gcaaaagaag ttctgttaat aagaggtccg ctggataatg ctgaaaacat taatgagcgg
     7741 tttgaagcta gcttttctta ccttcaaaaa caagacgtga ctatgtatgt gtgtgatagt
     7801 cagaattttg attttgaaaa tattcagcta gaagctagtt ccaacctcaa gtgttaccca
     7861 acaatagaca gtattatagc accttctgat atccatgcta ttgcttatat tcatgagctg
     7921 cattctcaag gtaaaaagtt tcctcaagat gttcaaataa taggttatga tgacatttta
     7981 atgagtcaat ttatttatcc ttctttatcg actattcatc aatcctctta tttgatgggc
     8041 cgttatgccg ccgaattagt ttatactatt gctagtcaat taactgtgaa agcaaatcgg
     8101 attaaattgc ctgttcacta cgttgagcga gaaacaataa ggaaaagata agtaataata
     8161 ttagtccaga ttttagcagg tatgatgaag atttattggg atttaccttc tactttaaaa
     8221 gatgttatct gtcattactt tcatcgctat cagtcaaaac gcattcttat gcaactctta
     8281 accttaagct taaggtcttt ttgataacat agaggaatgt tacacgatga tgacgcaata
     8341 aagcctaaat atagtaattg tcgtgatttt atagctagtg agtaatgaga tagcaagtct
     8401 ctcatttact tacaaaagtc aaaaaatagt gtataatggt tgagttacag ataacactgc
     8461 aaaaaagata acaagtgtcc ataattatct aagactataa aggcgatata gacagatata
     8521 aaaaagatga cgaatcagtt atcactggac aattaaccga tttagttaca actaatggat
     8581 ttttcagaaa ggtgtcaaat gaaaaaagaa atttcgccag aaatgtacaa ctataataaa
     8641 tttccaggtc ccaaatttat tcattttgaa gagcaagtta aggctgaagg cattgatttg
     8701 ttactcttag aagatgttaa gaacgctttt gatacgacta gctttggtca acgttataca
     8761 gaagttctcc taaagtatga ctatattgtt ggcgattggg gaaatgaaca gcttcgtctt
     8821 aaagggtttt ataaggatag tgacgatatc aagaaaacga atcgcatctc acgtttagaa
     8881 gattatatta aagaattttg caattttggt tgtgcttatt ttgttttaga aaatcttcat
     8941 ccacaagata ttaaatttga agaggagcgc caaccaagac gaaagaaatc acctaaatca
     9001 aaatcaaatc gtcgcaagcc aaactattca aatcagcagc ccgcaacacc taagagtaaa
     9061 tcgaagcggg tatcaaaaga aaagcaacct gaaaaccaag cgtttaccag tcaaaaacgt
     9121 cgaagtaata ctaagcataa agaaaagtca aaacgtaatc agactagtca acttaatacc
     9181 aaaattagtc attttatcat cagaaagaaa gataaataat ccatgaaacc atcgatttat
     9241 agcttaacac gcgatgaact gatcgcgtgg gcagttgaac gcggccaaaa acagtttaga
     9301 gctactcaaa tttgggattg gctctataaa aaaagagttc aatcttttga ggagatgacg
     9361 aatatttcta aagattttgt ttctatttta aatgatagtt tctgtgtcaa tcctttaaaa
     9421 cagcgagttg tacaagagtc agctgatggt acagtaaaat atttatttga actgcccgat
     9481 ggtatgttaa ttgaaacagt tttaatgcgt caacattatg gtcattctgt ttgtgtgacg
     9541 actcaagttg gctgtaacat tggctgtact ttttgtgcta gtggattgat caaaaagcaa
     9601 cgtgatctaa acagtgggga aattacagct caaatcatgt tagtccaaaa atattttgac
     9661 gatagaaagc aaggtgagcg ggttagccat gttgtcgtaa tgggcattgg tgaacctttt
     9721 gataattaca aaaatgtcat gtgctttctt cgcgtcatca acgatgataa tggcttagca
     9781 attggtgccc gtcatattac agtctctacc tcagggttag ctcacaagat tcgggatttt
     9841 gcaaacgagg gagtacaggt taatttagca gtctcgttgc atgcaccaaa taatgattta
     9901 cgttcaagga ttatgcgagt aaatcgctct tttccgcttg aaaagctctt ttcagctata
     9961 gaatactata ttgaaaaaac gaatcgtcgt gtcacttttg aatacattat gctaaatgaa
    10021 gttaacgata gcattaagca agctcaagaa ttagcagact taactaaaac tattcgtaag
    10081 ttatcttatg ttaacttgat tccgtataat cctgtttcag aacatgatca gtatagtaga
    10141 agtcctaaag agcgagttct agcgttttat gatgtgctaa agaaaaatgg agttaactgt
    10201 gtggtgcgtc aagagcacgg aacagatatt gatgcagcct gtggccagtt acgttctaaa
    10261 acgatgaaaa aagatcgcga aaaggttaca gcgacaaaat aaagcccaaa aaatatcttt
    10321 gattgacaat gcttgatgac aaaatattcc tagtcactaa aatgactagg ttttttatct
    10381 ggcctaaaaa tgctctagaa gcacaatcca aaataatcca aaactaagat aaggaataaa
    10441 aggtatgcgc ttgatgccta atagtaagca agcagtaata cctgctaaac tagcaagttg
    10501 aattagccaa atcaacgacg ttagatccaa tactaaagct aagctagcaa ggtagaaaaa
    10561 atcgcctgct ccaattgaaa aaggtcttaa atgagctaat aaacctagta gcagtaatat
    10621 caatgataaa taattgatcg aataaaacag gagtagactt acaaagctaa aaagccacaa
    10681 gataaaaggg tattcttgag aacgccaatc aaataaacta aataataaag aaaagagtaa
    10741 caagtaacag taactagcac taacccaatg taccatacta gcccataaga taattattag
    10801 acttatctct aagctaaaga agattttttg gctagttata aaatggtttt ggaactgccg
    10861 aaaaacgcgt ttggcaaaag ttagttggtc acaaacaatg atagtctgtt tacttagctg
    10921 ttcttgacca ttatcaggaa aataaagtag taaacagtaa aaaagatggg tcaataagat
    10981 gcccgaacat atactaaaaa aagctatcat acttatttat tcgaaaagaa atcaaatact
    11041 tgcaatcttt ccttaatcat tgtagaatat agatataaaa cgataatgat tctaattaag
    11101 tgtctaatca tccaattagg attattccgt tattgtcgaa taggattagg tccttaaccc
    11161 tttcttatgt ttatcacgtt agggttagtt ccccctccat tcttgccctt taagctgaaa
    11221 agtaaggaga tgttattatg acaaacacac tcgttgaaaa tatttatgct tcagtaactc
    11281 acaatatttc taaaaaagaa gcatcaaaaa atgaaaaaac taaagctgtt ttaaaccaag
    11341 ctgtcgctga cttatctgtg gctgcatcta ttgtgcacca agtacactgg tatatgcgtg
    11401 gtccaggttt cttgtacctt cacccaaaaa tggatgaatt acttgatagc ttgaatgcta
    11461 atttagatga aatgagcgag cgtttgatca ctattggcgg agcgccttat tctaccctag
    11521 ctgagttttc taaacactct aaattggacg aagcaaaagg tacttacgat aaaacagttg
    11581 ctcagcattt agcaagattg gtcgaagttt acctttacct cagcagcctt taccaagttg
    11641 gtttggatat taccgatgaa gaaggcgatg ctggaacaaa tgatttgttt acagcagcta
    11701 agacagaggc tgaaaaaacc atttggatgc tccaagcaga gcgtggacaa ggcccagcac
    11761 tctaattgat tatgccttag gataaaagaa gtcaatgata aaattggctt cttttttatg
    11821 gaatcatcga ttcattttca gaaacataga aagcgattcc atacttgtct tgaaatttgc
    11881 cgtagaattt gctaaaatct acttatatga aaacactata tgatgtgcaa caattgctaa
    11941 aaaactttgg catttttgtt taccttggca aacgtctcta tgatattgaa atgatgaaga
    12001 ttgaacttca gcgtctctat gatagcggct tattggataa gagggattac ttaaatgcgg
    12061 agttaatttt gcgacgtgag catagattag aattggaaaa agaaggatag acaaatgagt
    12121 caaaaattac tggggattga tttaggtggt accaccatta aatttggaat tttaacagca
    12181 gcaggagaag tccaagaaaa atgggcaatt gagactaata ttttagaagg aggcaagcat
    12241 attgttcccg atattgtagc ttccatcaaa catcgcttag acttgtatgg tctaagcagt
    12301 gctgattttg tgggaattgg tatgggatca ccaggagcgg ttgaccgtga tactaataca
    12361 gttactgggg cattcaacct taattggaaa gaaacccaag aagtcggttc cgttgttgaa
    12421 aaagaattgg gcattccttt tgccattgac aatgatgcta atgtggctgc ccttggtgaa
    12481 cgttgggtag gtgctggtga aaataaccca gatgtcgtct tcatgacact tggaacaggt
    12541 gtcggtggag gcattattgc tgatggtaac ttgattcatg gtgttgcagg agcaggtggt
    12601 gaaatcggcc acatgattgt tgagccagaa aatggctttg cttgtacttg tggctcacac
    12661 ggctgtttgg aaacagtagc ttcagcaaca ggagttgtca aagtggcacg tttattggca
    12721 gaagcttatg aaggggattc agccatcaaa gcagctattg acaatggtga aggtgttacc
    12781 agcaaagata tttttatggc agctgaagca ggggattcct ttgctgattc tgttgtggaa
    12841 aaggttggtt actaccttgg ccttgcttca gcaaatattt ccaatatatt gaatccagac
    12901 tcagtggtta tcggtggggg tgtgtcagca gcaggagaat ttctacgctc acgtattgaa
    12961 aaatactttg tgaccttcac tttcccacaa gtgaggtatt caactaaaat taagattgca
    13021 gagcttggca atgatgctgg aattatcggt gcagctagcc ttgctcgaca atttatcaca
    13081 aaataggagg gggatatgtc tccaatcaca cttatcttat ggttacttct tgtcggcatt
    13141 gttggttact acacatggaa ctatttctct tttcgaaaaa tggcaaagca ggttgataac
    13201 gagactttta aagacgtgat gcgtcaaggt caattgattg atttacgaga gccagcggct
    13261 tttagagcta agcatatttt aggagctcga aattttccag cgcaacaatt tgatgctgct
    13321 attaagggac tacgcaagga caaacctgtt cttatttacg aaaatatgcg tccccagtac
    13381 cgtgtgcctg cggtcaaaaa acttaaaaaa gctggctttg aagacgttta tgtcttaaaa
    13441 gacggtattg attattggga tggcaaagtt aaacaaacaa cctagttaag agtaacgtgg
    13501 agttaagggg aataaaggca gtcactgtct caaaaacctt aattcctttt tttgctgtat
    13561 ccagacttgc tgaaagtctg aaaacattta caattcatta aaaccagttt tttaaaacat
    13621 tttgtgttat acttatctag ttaaaatata tttacttaga ggaacaaatg actaacttaa
    13681 gaaacgatat ccgtaacgta gcgattattg cccacgttga ccacggaaaa acaacacttg
    13741 tagatgaatt attaaaacaa tcccatactc ttgatgagcg taaagagctt caagagcgtg
    13801 ccatggattc caatgacctt gaaaaagaac gtgggattac gatccttgcg aaaaatacgg
    13861 cagtagccta taacgatgtt cgtattaaca tcatggatac cccaggacac gcggacttcg
    13921 gtggtgaagt tgaacgtatc atgaaaatgg ttgacggggt tgttcttgtt gtggatgcct
    13981 acgaaggaac aatgccccag acgcgtttcg tattgaaaaa agcacttgag caaaacctta
    14041 tcccgatcgt tgtggtgaac aagattgaca aaccttcagc tcgtccagca gaagttgtag
    14101 atgaagtgct tgaattattc atcgaacttg gtgccgatga tgagcaattg gaattcccag
    14161 ttgtttacgc atcagctatt aatggcacat catcattatc agatgatcct gctgaccaag
    14221 agcatactat ggcacctatc tttgatacga ttattgatca tattccagcg ccagttgata
    14281 attcagatga gcctttgcaa ttccaagtgt cacttttgga ctacaacgat ttcgtaggtc
    14341 gtatcggtat cggtcgtgtt ttccgtggta ctgttaaagt gggtgaccaa gtaactcttt
    14401 caaaacttga tggtaccact aaaaacttcc gtgttacaaa actgtttggt ttcttcggtt
    14461 tggaacgtcg tgaaattcaa gaagctaaag caggtgactt gattgctgtt tcaggtatgg
    14521 aagatatctt tgttggagaa accattacac caactgactg tgtggaagct ctgccaattc
    14581 ttcgtattga tgagccaacg cttcagatga ctttcttggt caataactct ccttttgcag
    14641 gtcgtgaggg taaatggatc acgtcacgta aggttgaaga acgtctttta gcagaattgc
    14701 aaacagacgt gtcacttcgt gttgacccaa cagattcgcc agataaatgg acggtttcag
    14761 ggcgtggaga attgcacttg tcaattctta tcgaaaccat gcgccgtgaa ggctatgaac
    14821 ttcaagtatc acgtccagaa gttatcatca aagaaattga tggtgtcaaa tgtgaaccgt
    14881 ttgagcgtgt tcaaattgat acaccagaag aatatcaggg tgcaatcatc cagtctcttt
    14941 cagaacgtaa aggggatatg cttgatatgc agatggttgg taatggtcaa acgcgtttga
    15001 ttttcttgat tcctgcacgt ggtttgattg gttattcaac agagtttctt tcaatgacac
    15061 gtggatatgg tatcatgaat catacttttg atcagtatct accggttgtt caaggagaaa
    15121 ttggtggccg tcatcgtggt gccttggttt ctattgaaaa tgggaaagca acgacatatt
    15181 caatcatgcg tattgaagaa cgcggaacta tctttgtcaa cccaggtaca gaagtttacg
    15241 aagggatgat tgttggtgaa aactcacgtg ataacgacct tggtgttaac attacaacag
    15301 ctaagcaaat gacaaatgtc cgttcagcga ctaaagatca aactgcagtt atcaagacgc
    15361 ctcgtatcct aacgcttgaa gaatcattag agttcttgaa tgacgacgaa tacatggaag
    15421 taacgccaga atctatccgc ttgcgtaaac aaatcttgaa taaagctgcg cgtgataaag
    15481 ctaataaaaa gaaaaaatca gccgaatagc ttttgaagtt aaactaacta aataaaatag
    15541 caaaaagata tttaagaaaa gtcatttttt aaaggtcttt ttgcgtttac aagttcctat
    15601 ggaatataaa ccaaaataaa ggaggacgga atgttttacc ttattatggc tgtcttgatt
    15661 atatcttatt atctatacat ggctcctaaa agtgtccgta acacccttgg gatgattggt
    15721 ttagttggct tggttgctct gcttattgtt ttagcaggct tgagttttat caaaatcatg
    15781 caaacccctc ctgaattttt tattgggatg ggaatgatgg cattgggcta ttttgcttta
    15841 aaagatgtgc gtaaaatgac caaaaaaccg agagttaaat aaaaatactt aaagattgat
    15901 gattttggtt tttatacgat aaaaggactg atttgtttta gacaatatca gtcctttttt
    15961 aatagttcat tttttctgaa agaaagcttt tagccgattt tcattgagtg tgcaactaaa
    16021 aagagatgct tggtagtgac agttaagacc tctgactagt attttatctt attttactta
    16081 aaaaaacgta ccaataatct cacaaatatg ggcatgatgt ttgtatattg gaaacggatt
    16141 ctaattctaa actcaagaac ggtattttta aaatgttgaa aaagcatcta aataaaggta
    16201 aaatagaaat caaatagaat ggatagtgtg agcttagatg aaagtgataa gtaattttca
    16261 aaacaaaaaa atattaatat tggggttagc caaatcgggc gaagcagcag caaaattatt
    16321 gactaaactt ggtgctttag tgactgttaa tgatagtaaa ccatttgacc aaaatccagc
    16381 ggcacaagcc ttgttggaag aggggattaa ggtcatttgt ggtagccatc cagtagaatt
    16441 attagatgag aactttgagt acatggttaa aaaccctggg attccttatg ataatcctat
    16501 ggttaaacgc gcccttgcaa aggaaattcc catcttgact gaagtagaat tggcttattt
    16561 cgtatctgaa gcgcctatta tcgggattac aggatcaaac gggaagacaa ccacaacgac
    16621 aatgattgcc gatgttttga atgctggcgg gcaatctgca ctcttatctg gaaacattgg
    16681 ttatcctgct tcaaaagttg ttcaaaaagc aattgctggt gatactttgg tgatggaatt
    16741 gtcctctttt caattagtgg gagtgaatgc ttttcgccct catattgctg tcatcactaa
    16801 tttaatgccg actcacctgg actatcatgg cagttttgag gattatgttg ctgctaaatg
    16861 gatgattcaa gctcagatga cagaatcaga ctatcttatt ttaaatgcta atcaagagat
    16921 ttcagcaact ctagctaaga ccaccaaagc aacagtgatt cctttttcaa ctcaaaaagt
    16981 ggttgatgga gcttatctga atgatggaat actctatttt aaagaacagg cgattatagc
    17041 tgcaactgac ttaggtgtcc caggtagcca caacattgaa aatgccctag caactattgc
    17101 agttgccaag ttatctggta ttgctgatga tattattgcc cagtgccttt cacattttgg
    17161 aggcgttaaa catcgtttgc aacgggttgg tcaaatcaaa gatattacct tctacaatga
    17221 cagtaagtca accaatattt tagccactca aaaagcttta tcaggttttg ataacagtcg
    17281 cttgattttg attgctggcg gtctagatcg tggcaatgaa tttgacgatt tggtgccaga
    17341 ccttttagga cttaagcaga tgattatttt gggagaatcc gcagagcgta tgaagcgagc
    17401 tgctaacaaa gcagaggtct cttatcttga agctagaaat gtggcagaag caacagagct
    17461 tgcttttaag ctggcccaaa caggcgatac tatcttgctt agcccagcca atgctagctg
    17521 ggatatgtat cctaattttg aggttcgcgg ggatgaattt ttggcaacct ttgattgttt
    17581 aagaggagat gcctaatgcc taagaagatt ttatttacag gtggtggaac tgtaggtcat
    17641 gtcaccttga acctcattct cataccaaaa tttatcaagg acggttggga agtacattat
    17701 attggtgata aaaatggcat tgaacataca gaaattgaaa agtcaggcct tgacgtgacc
    17761 tttcatgcta tcgcgacagg caagcttaga cgctattttt catggcaaaa tctagctgat
    17821 gtttttaagg ttgcacttgg cctcctacag tctctcttta ttgttgccaa gcttcgccct
    17881 caagcccttt tttccaaagg tggttttgtc tcagtaccgc cagttgtggc tgctaaattg
    17941 cttggtaaac cagtctttat tcatgaatca gatcggtcaa tgggcctagc aaacaagatt
    18001 gcctacaaat ttgcaactac cgtgtatacc acttttgagc aggaagacca gttgtctaaa
    18061 gttaaacacc ttggagcggt gacaaaggtt ttcaaagatg ccaaccaaat acctgaatca
    18121 actcagttag aggcggtgaa tgagtatttt agtagagacc taaaaaccct cttgtttatt
    18181 ggtggttcgg caggggcgca tgtgtttaat cagtttatta gtgatcatcc agaattgaag
    18241 caacgttata atatcatcaa tattacagga gaccctcacc ttaatgaatt gagttctcat
    18301 ctgtatcgag tagattatgt taccgatctc taccaacctt tgatggcgat ggctgacctt
    18361 gtagtgacaa gagggggctc taatacactt tttgagctac tggcaatggc taagctacac
    18421 ctcatcgttc ctcttggtaa agaagctagc cgtggcgatc agttagaaaa tgccacttat
    18481 tttgagaaga ggggctacgc taaacaatta caggaacctg atttaacttt gcataatttt
    18541 gatcaggcaa tggctgattt gtttgaacat caggctgatt atgaggctac tatgttggca
    18601 actaaggaga ttcaatcacc ggacttcttt tatgaccttt tgagagctga tattagctcc
    18661 gcgattaagg agaagtaaat ggcaaaagat aaagagaaac aaagtgatga caagctcgtt
    18721 ttgacagagt ggcaaaagcg taacattgaa tttttaaaga aaaagaagca gcaagctgag
    18781 gaagaaaaaa aactcaaaga gaaattattg agtgataaaa aagcgcagca gcaagctcaa
    18841 aatgcttctg aagcagttga gcttaaaact gatgagaaaa ctgatagtca ggaaattgag
    18901 tcagaaacga cgtcaaaacc taaaaaaccc aaaaaagtta gacaacccaa ggaaaaaagc
    18961 gcgacacaaa tcgcttttca aaaatccttg cctgttcttt tgggggcgct cttactcatg
    19021 gcggtgtcta tttttatgat cactccttat agcaaaaaga aagagttttc tgtaagagga
    19081 aaccatcaaa cgaaccttga cgaattaatc aaagctagca aagtcaaaac atctgactat
    19141 tggttaacgt tgttaacttc gcctggtcag tatgaacgac cgattcttca tactattcca
    19201 tgggtgaaat ctgtacatct ttcttaccaa tttcctaatc actttctatt taacgttatt
    19261 gaatttgaaa tcatcgctta tgcacaagtc gaaaacggtt ttcagcctat tttggagaat
    19321 ggaaaacgtg ttgacaaggt cagggcatca gaactaccga aatctttctt gattcttaat
    19381 ttaaaagatg agaaagcgat ccaacagtta gttaagcaat taacgacatt acctaaaaaa
    19441 ttagtcaaga atatcaagtc agtatctctt gcaaattcca aaacgacagc ggatttacta
    19501 cttattgaaa tgcatgacgg taatgtagtt agagtaccgc agtcacaact cacattgaaa
    19561 cttccctatt atcaaaaatt gaaaaaaaaa cttgaaaatg atagtatagt ggatatggaa
    19621 gttggaattt atactacaac acaggagatt gaaaatcaac ctgaagttcc tcttacgcca
    19681 gaacaaaacg cagctgataa agaaggagat aagcctggtg aacatcagga acagacagac
    19741 aatgattcag aaacgccagc aaatcagagt agtcctcagc aagcaccacc atccccagaa
    19801 acggttctcg aacaggccca tggctagcta atatctaagt tgaaaaagca atgaaaacgt
    19861 tagaaattca acgattctaa cccataatga attgcctaaa aaaaattaag tttatataac
    19921 aaaaaacgta aaatgataac attttacgtt tttttatggt ataatatttt ctgaatgatt
    19981 ctgtttttta gcagttttta gaatagcaaa agtttggaaa gtaagtgagg tcaagtgaat
    20041 ggctagaaat ggctttttta ctggtttgga cattggaaca agctcgataa aagttttagt
    20101 agcagaattt atttctggtg agatgaacgt cattggtgtt agtaatgttc caagtaccgg
    20161 cgtaaaagat ggcataataa tcgatataga ggcagctgcg actgccatca aaactgcggt
    20221 agaacaagca gaagaaaaag cagggatgac aattgaaaag gttaatgttg ggctaccggc
    20281 aaaccttctt caaattgaac caacacaagg aatgattcct gtcccaagtg agtctaaaga
    20341 gataaaagat gaggatgttg atagcgttgt taaatcggct ttaacaaaaa gtatcacacc
    20401 agaacgagag gttatctctt tagttccaga agagttcatt gtggatggct ttcagggcat
    20461 tcgagatcca cgtggtatga tggggattag attagagatg cgcggtctta tttatactgg
    20521 accaagcacc attttacata atctgcgtaa aacggtagaa agagcaggca ttaaagttga
    20581 aaacatcatt atttctccgt tagctatggc taaaaccatt ttaaacgaag gtgagcgcga
    20641 gtttggagct actgtaattg atatgggagg tggacagaca actgtcgctt ctatgcgagc
    20701 acaagaattg cagtatacca atatatatgc tgaaggcggc gaatacatta ctaaagatat
    20761 atcaaaagta ttaaaaacgt ctttggctat tgcagaagca cttaagttta attttggtca
    20821 agcggagata tcagaagcca gtataactga aacagtaaaa gttgatgtgg taggtagtga
    20881 agagcctgtt gaggtaactg aacgttattt atctgaaatt atttcagcgc gtattcgtca
    20941 tattttagat cgtgtgaagc aagatttgga aagaggtcgt ttactagact taccgggagg
    21001 cattgttttg attggtggcg gtgcaatcat gcctggagtg gtagaaattg cacaagaaat
    21061 ctttggagta actgtaaagc tccatgttcc aaaccaagtc ggtattagaa atccaatgtt
    21121 ttcaaacgtt atcagtttgg tagaatatgt tggtatgatg tctgaagtag acgttttagc
    21181 acaaactgca gtttcaggag aagaactttt gcgacgcaag cctatcgatt tcagtggcca
    21241 agaatcttat ttaccagatt atgatgattc aagaagacca gaatcgacca ttggctatga
    21301 acaacaagcg tcacaaacag catatgattc acaagttccg agtgatccta aacaaaaaat
    21361 ttcagaacgt gttcgtggca tatttgggag tatgtttgat taaaagtaat aaagtgagga
    21421 aataaaatgg cattttcatt tgatactgca tcaattcaag gtgcaattat aaaagtaatt
    21481 ggagtcggcg gaggtggcgg aaatgccatt aatcgtatga ttgatgaagg tgttgctggt
    21541 gtcgagttca tcgcagcaaa cacagacatt caggcattaa gctcatcaaa agctgaaacg
    21601 gttattcaac taggccctaa attaactcgt ggacttggtg ctggagg
//
LOCUS       DAXMQE010000032        20290 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.032, whole genome shotgun sequence.
ACCESSION   DAXMQE010000032 DAXMQE010000000
VERSION     DAXMQE010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20290)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20290)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20290
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.032"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            complement(88..1041)
                     /gene="manA"
                     /locus_tag="ACF4ZO_001411"
     CDS             complement(88..1041)
                     /gene="manA"
                     /locus_tag="ACF4ZO_001411"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004476 - mannose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HFD5486938.1"
                     /translation="MSEPLFLKSTMHDRIWGGTKLRDVFAYNIPSDTTGEYWAISAHP
                     NGVSTVTNGRYQGQPLNTLYAQEPALFGNPKEEVFPLLTKILDANDWLSVQVHPDDAY
                     GREHEGELGKTECWYIISAEEGSEIVYGHQAKSKEDLRAMIEAGAWDDLLTRVPVKAG
                     DFFYVPSGTMHAIGKGILILETQQSSDTTYRVYDFDRKDVNGNLRDLHIEKSIDVLTI
                     GKPENSVPATMVLDNMVATTLVSTPFFTVYKWVTSQMVDMKQAAPYLLVSVLKGQGKL
                     YVDQKAYELEKGMNFILPNDVKSWSFDGQLEMIVSHPNQLV"
     gene            complement(1136..2020)
                     /gene="scrK"
                     /locus_tag="ACF4ZO_001412"
     CDS             complement(1136..2020)
                     /gene="scrK"
                     /locus_tag="ACF4ZO_001412"
                     /EC_number="2.7.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008865 - fructokinase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructokinase ScrK"
                     /protein_id="HFD5486939.1"
                     /translation="MGKLYGSIEAGGTKFVCAVGDEEFTVVDKTQFPTTTPEETIART
                     IAYFKAFEADLAGMTIGSFGPIDIDPSSETYGYITTTPKSGWANVDLLGQLSAAFKIP
                     FDVTTDVNSSAYGEVLARPGVESLVYYTIGTGIGAGAIQHGHFIGGLGHTEAGHTYVM
                     PHPDDMAKGFLGVCPFHKGCLEGMAAGPSIEARTGVRGERLDQEADVWDIQAFYIAQA
                     ALQATMLYRPQVIVFGGGVMAQEHMVLRVHDKFTTLLSGYLPVPDLTDYIVTPAVADN
                     GSATLGNFALAKLAAQGK"
     gene            complement(2284..5283)
                     /locus_tag="ACF4ZO_001413"
     CDS             complement(2284..5283)
                     /locus_tag="ACF4ZO_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase family
                     protein"
                     /protein_id="HFD5486940.1"
                     /translation="MDKHLLVKRTLGCVCAATLMGAALATHHDSLNTVKAEEKTVQVQ
                     KELSSIDSLHYLSENSKKEFKEELSKEKVPEKVKEILAKAQQADKQAQELAKMKIPEK
                     IPMKPLHSPLYGGYFRTWHDKTSDPTEKDKVNSMGELPKEVDLAFIFHDWTKDYSLFW
                     KELAIKHVPKLNKQGTRVIRTIPWRFLAGGDNSGIAEDTSKYPNTPEGNKALAKAIVD
                     EYVYKYNLDGLDVDVEHDSIPKVNGKASDENLKRSIDVFEEIGKLIGPKGADKSRLFI
                     MDSTYMADKNPLIERGAPYIDLLLVQVYGARGEQGEFQNDTRLVTETPEERWQGYSKY
                     IRPEQYMIGFSFYEERAGSGNLWYDINSRKDEDKANGINTDITGTRAERYARWQPKTG
                     GVKGGIFSYAIDRDGVAHQPEKVAQQDKRSQTQVDEITDNIFHSDYSVSKALKTVMLK
                     DKSYDLIDEKDFPDKALREAVMAQVGTRKGDLERFNGTLRLDNPAIQSLEGLNKFKKL
                     AQLDLIGLSRITKLDQSVLPANMKPGKDTLETVLETYKKDNKEEPATIPPVSLKVSGL
                     TGLKELDLSGFDRETLAGLDAATLTSLEKVDISGNKLDLAPGTQNRQIFDTMLSTVSN
                     HVGSNEQTVKFDKQKPTGHYPDTYGKTSLRLPVANEKVDLQSQLLFGTVTNQGTLINS
                     EADYKAYQNHKIAGRSFVDSNYHYNNFKVSYENYTVKVTDSTLGTTTDKTLATDKEET
                     YKVDFFSPADKTKAVHTAKVIVGDEKTMMVNLAEGATVIGGSADPVNARKVFDGQLGS
                     ETDNISLGWDSKQSIIFKLKEDGLIKYWRFFNDSARNPKTTNKPIQEASLQIFNIKDY
                     NLDNLLENPNKFDDEKYWITVDTYSAQGERATAFSNTLNNITSKYWRVVFDTKGDRYS
                     SPVVPELQILGYPLPNADTIMKTVTTAKGLSQQKDKFSQKMLDELKIKEMALETSLNS
                     KIFDVTAINANAGVLKDCIEKRQLLKK"
     gene            complement(5514..7397)
                     /locus_tag="ACF4ZO_001414"
     CDS             complement(5514..7397)
                     /locus_tag="ACF4ZO_001414"
                     /EC_number="2.7.1.211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-specific PTS transporter subunit IIBC"
                     /protein_id="HFD5486941.1"
                     /translation="MDNRQIAAEVIEALGGRENVRSVAHCATRLRVMVYDEGKIDKEK
                     AEAIDKVKGAFFNSGQYQMIFGTGTVNNIYDEVVALGLPTSSTSEQKAEAGKQGNIFQ
                     RAIRTFGDVFVPIIPAIVATGLFMGVRGLVTQPAIMDLFGVHEYGENFLMYTRILTDT
                     AFVYLPALVAWSAFRVFGGNPIIGIVLGLMLVSNELPNAWVVASGGDVKPLTFFGFVP
                     VVGYQGTVLPAFFVGLVGAKLEKWLHKKVPEALDLLVTPFLTFAIMSTLGLFVIGPVF
                     HSLENLVLAGTQAVLHLPFGIAGLIVGGIQQLIVVTGIHHIFNFLEAQLIANTGKDPF
                     NAYLTAATAAQAGATLAVAVKTKSPKLKGLAFPSTLSALLGITEPTIFGVNLRYPKVF
                     VSGLIGGALGGWVAGLFGIAGTGFGITVLPGTLLYLNGQLLQYLVTMLVGLGVAFAIA
                     YTWGYQDREPLPLPAVEVDQTANQPALAEETLYSPLNGIVVDLAAVSDPVFSSGAMGQ
                     GLAIKPEGKALYSPVDGKVAIVFETGHAYAITSSQGAEVLLHIGIDTVSMAGDGFESL
                     VAVGQAVKKGDLLGHFDPSKIAEAGLDDTTMMIVTNSADYQSVDILAQGHVLIGDQVA
                     LIK"
     gene            7639..9078
                     /locus_tag="ACF4ZO_001415"
     CDS             7639..9078
                     /locus_tag="ACF4ZO_001415"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004564 - beta-fructofuranosidase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HFD5486942.1"
                     /translation="MDLPQAIRYRPYKGWSSKDYQAITEKMAQSPWHSQFHVEPKTGL
                     LNDPNGFSYFNGRYHLFYQNWPYGAAHGLKQWVHMTSTDLVHFTETRSRLLPDHAHDS
                     HGAYSGSAYAIDDKLFLFYTGNVRDANWVRTPLQVGAWMDKQGNISKIPQVLIEQPDD
                     VTEHFRDPQLFSYQGQFYAIIGAQGLDGKGKIKLYKAVDNHVDNWRFIADLDFDDSGT
                     EYMIECPNLVFVDDKPVLIFSPQGLAKADLDYQNIYPNTYKIFESFNPETGQLLGGGA
                     LQNLDFGFEAYATQAFNAPDGRALAVSWIGLPDIDYPTDRYDYQGALSLVKELRIRDG
                     ILYQAPVSALKDLRGPAELFHNKIDSSNCYELELTIPGQKKLDLLLFADQKGNGLRLK
                     VDTTKGQLSIDRSRAGVQYAQDYGTVRSCQIPQSHVTLNVYVDNSILEIFINQGQKVL
                     TSRVFPTQGQTGIQVVEGQAFGHYYEMRY"
     gene            9083..10048
                     /locus_tag="ACF4ZO_001416"
     CDS             9083..10048
                     /locus_tag="ACF4ZO_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFD5486943.1"
                     /translation="MVSKLTDVAALAGVSPTTVSRVINKKGYLSQKTVNKVNKAMREL
                     GYKPNNLARSLQGKSTQLIGLIFPNISNIFYAELIEHLEIELFKQGYKTIICNSEHNP
                     VKEREYLEMLAANQVDGIISSSHNLGIEDYERVEAPIVAFDRNLAPNIPVISSDNFEG
                     GKLAAQTLQKHGCQNIVMITGNDNSDSPTGLRQLGFNYQLKRSAEIIKLPNNLSPVRR
                     EMEIKSILATRKPDGLFVSDDLTAILIMKVAKQLHITIPEDMKVIGYDGTTFIQQYVP
                     QLATIRQPIDEIAKLSVEILIKKIKKEKTSKDYILPITLLPGASI"
     gene            complement(10189..10641)
                     /gene="nusB"
                     /locus_tag="ACF4ZO_001417"
     CDS             complement(10189..10641)
                     /gene="nusB"
                     /locus_tag="ACF4ZO_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HFD5486944.1"
                     /translation="MTNSFQNSRRDLRERAFQALFNIETGAELLAASQFAYGYDKVTG
                     EDAQVLELPIFLLSLVTGVNNHKEELDNLISTHLKKGWSLERLTLTDKTLLRLGLFEI
                     KYFDETPDRVALNEIIEVAKKYSDETSAKFINGLLSQYVSEAPSANKS"
     gene            complement(10634..11023)
                     /locus_tag="ACF4ZO_001418"
     CDS             complement(10634..11023)
                     /locus_tag="ACF4ZO_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HFD5486945.1"
                     /translation="MTTEYIGEIVISPRVLEVITGIATTQVEGVHSLHNKKMADSFNK
                     ASLGKGVYLQTEEDGSVTADIYVYLQYGVKVPTVSMNIQKTVKSAVYDMAEVPISAVN
                     IHVEGIVAEKTPKPDLKSLFDEDFLDD"
     gene            complement(11069..11626)
                     /gene="efp"
                     /locus_tag="ACF4ZO_001419"
     CDS             complement(11069..11626)
                     /gene="efp"
                     /locus_tag="ACF4ZO_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HFD5486946.1"
                     /translation="MIEASKLKAGMTFEAEGKLIRVLEASHHKPGKGNTIMRMKLRDV
                     RTGSTFDTTYRPDEKFEQAIIETVPAQYLYKMDDTAYFMNTDTYDQYEIPVANVEQEL
                     LYILENSDVKIQFYGSEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATLETGLVV
                     NVPDFIEAGQKLIINTAEGTYVSRA"
     gene            complement(11722..12183)
                     /locus_tag="ACF4ZO_001420"
     CDS             complement(11722..12183)
                     /locus_tag="ACF4ZO_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HFD5486947.1"
                     /translation="MTNRLSWQDYFMANAELISKRSTCDRAFVGAVLVKDNRIIATGY
                     NGGVSATDNCNEAGHYMEDGHCIRTVHAEMNALIQCAKEGISTDGTEIYVTHFPCINC
                     TKALLQAGITKITYKAHYRPHPFAIELMEKKGVAYVQHDVPQIVLGGDKEQ"
     gene            complement(12218..13291)
                     /locus_tag="ACF4ZO_001421"
     CDS             complement(12218..13291)
                     /locus_tag="ACF4ZO_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M24 family metallopeptidase"
                     /protein_id="HFD5486948.1"
                     /translation="MSGFLEQRLGHCLRQMVEKGLEALLVTHLTNSYYLTGFSGTAAT
                     VLITAKRRVLITDSRYTLLAKASVEGFDIIESRTPLKVVAELLEADQIDCLGFEDQVS
                     FSFYQAMQAELSGITLLAQSGFVEHLRLIKDASEIETIAKACSISDKAFEDALDFIKP
                     GTTTERDLANFLDFRMRQYGASGTSFDIIVASGYRSAMPHGRASDKVIQNKESLTMDF
                     GCYYNHYVSDMTRTIHIGQVTDEEREIYALVLAANKALIAKASAGMTYSDFDGIPRQL
                     ITEAGYGSHFTHGIGHGIGLDIHENPFFGKSEQLLQAGMVVTDEPGIYLDNKYGVRIE
                     DDLVITKTGCQVLTLAPKELIVL"
     gene            complement(13407..16235)
                     /gene="uvrA"
                     /locus_tag="ACF4ZO_001422"
     CDS             complement(13407..16235)
                     /gene="uvrA"
                     /locus_tag="ACF4ZO_001422"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HFD5486949.1"
                     /translation="MQNKIIIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TIYAEGQRRYVESLSAYARQFLGNMEKPDVDSIDGLSPAISIDQKTTSKNPRSTVGTV
                     TEINDYLRLLYARVGTPYCINGHGAITASSAEQIVEQVLALPERTRMQILAPIVRRKK
                     GQHKTIFEKIQKDGYVRVRVDGDIFDVTEVPELSKSKMHNIEVVIDRLVNKDGIRSRL
                     FDSVEAALRLGDGYLMIDTMDGNELLFSEHYSCPVCGFTVPELEPRLFSFNAPFGSCP
                     TCDGLGIKLEVDLDLVVPDPSKSLKEGALAPWNPISSNYYPTMLEQAMASFGVDMDTP
                     FEALTEEERDLVLYGSGDREFHFHYVNDFGGERNIDIPFEGVVTNVNRRYHETNSDYT
                     RNVMRGYMNELTCATCHGYRLNDQALCVHVGGEEGPHIGQISELSIADHLQLLEELEL
                     TENESTIAKPIVKEIHDRLTFLNNVGLNYLTLSRAAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIESLKKMRDLGNTLIVVEHDEDTMMQADWLIDVGPGA
                     GEFGGEIIASGTPKQVAKNKKSITGQYLSGKKFIPVPLERRSGNGRFIEIKGAAQNNL
                     QSLDVRFPLGKFIAVTGVSGSGKSTLVNSILKKAVAQKLNRNADKPGKYHSISGIEHI
                     ERLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFARTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVPCEVCHGRRYNSETLEVHYKEKNIAEVLDMTVDDALV
                     FFSAIPKIARKIQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSLYIL
                     DEPTTGLHTDDIARLLKVLERFVDDGNTVLVIEHNLDVIKSADHIIDLGPEGGVGGGQ
                     IVATGTPEEVAQVKESYTGHYLKVKLQQ"
     gene            complement(16449..16631)
                     /locus_tag="ACF4ZO_001423"
     CDS             complement(16449..16631)
                     /locus_tag="ACF4ZO_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Paratox"
                     /protein_id="HFD5486950.1"
                     /translation="MLTYDEFKQAIDRGYITGDTVMIVRKNGQIFDYVLPHEKVKNGE
                     VVTEEIVEEVMVELDK"
     gene            16869..17669
                     /locus_tag="ACF4ZO_001424"
     CDS             16869..17669
                     /locus_tag="ACF4ZO_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HFD5486951.1"
                     /translation="MSKANRRIWQGLAVILIAIITTFTTSTATAAKKIRNFPTTTEIL
                     SGTKATEAPGILPFTGSYKLVLGDLDNLRRPTFAHIQLKDQDEPKIQRKGLKFNPPGW
                     HNYKLTDANGKTTWLMDRGHLVGYQFSGLNDEPKNLVTMTKYLNTGFSDRNPLGMLYY
                     ENRLDSWLALHPNFWLDYKVTPIYHENELVPRQVILQYVGIDEDGNLLQIKLGGEKES
                     VDNYGVTSVTLDNVSPLAELDYQTGMMLDSTQNEEDSNVETEEFEEAA"
     gene            complement(17731..17931)
                     /locus_tag="ACF4ZO_001425"
     CDS             complement(17731..17931)
                     /locus_tag="ACF4ZO_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HFD5486952.1"
                     /translation="MSEEKLKAKVEQASGSLKEGAGKLTGDKELEAKGFVEKTIAKGK
                     ELADDAKEAVEGAVDAVKEKLK"
     gene            complement(18116..19087)
                     /locus_tag="ACF4ZO_001426"
     CDS             complement(18116..19087)
                     /locus_tag="ACF4ZO_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Abi family protein"
                     /protein_id="HFD5486953.1"
                     /translation="MKQPLALTWEDQIRLFEKRGLIVKADDVEKIKHISYYRIKEFAK
                     PLEIKRQDGEEKDILYDNIEFAEVLARYYQDKNLRIYLLHAIEKIEVSIKTKISFVLG
                     DRYGAFGYLNFSSWANRNKFTKYDIEKRQFRIKKNLLNTVRKSQLTELQKSINLDPDG
                     FPTVWLAIDLLMFGDIVSILTIMSEKNIKQICQYYSCTPEELVSWLKCLNFIRNVCAH
                     NSNVLDIQITTKPKLRSEWRNYIDTVKIKHNVTKPSNKLSVIIAIVVYLVNTINSKYQ
                     WRKIQSSLKALCKEDDSRAKLLGFKDYDSVKAMINGIKCTAFTNSKK"
     gene            complement(19378..20130)
                     /locus_tag="ACF4ZO_001427"
     CDS             complement(19378..20130)
                     /locus_tag="ACF4ZO_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HFD5486954.1"
                     /translation="MATLDEVLSFAKGLADTGQGVDLDNVYGTQCVDLPNWITTKYFG
                     IALWGNAIDLLDSAAAQGMEVVYNAPGVNPRAGAIFVMVTYAHGYGHTGLVIVTSDGY
                     VLHNIEQNVDGNADALYIGGPARYVDRPFEDGTGYILGWFYPPYDNTPVQEIEPSAPV
                     VAQSDGTYVVNPETGTFTVRVAALNVRSAPRLDAEIVATYGENMEFNYDGWIDSDGYI
                     WVTYISVTGVRRYVAVGNSQNGRRVTNFGTFR"
BASE COUNT         6078 a         4469 c         3561 g         6182 t
ORIGIN      
        1 ccagtagaaa tgttaaaact ggctaacttc aacttgaaat ttggcagtca taattttatt
       61 cttttttctc atattgatac catggtatta aacgagttga ttggggtgac tcacaatcat
      121 ttctaattga ccatcaaatg accacgattt aacatcgtta ggcaagataa agttcatgcc
      181 tttttctagc tcataagcct tctggtccac atagagtttt ccttgacctt ttaaaacact
      241 cactaaaaga taaggcgcag cttgtttcat gtcaaccatt tgactagtca cccatttgta
      301 aacagtgaaa aatggcgttg agactaaagt tgttgctacc atattatcca aaaccatagt
      361 ggctggcacg ctattttctg gcttaccaat cgttaagaca tcaatagact tttcaatatg
      421 aaggtcacga agattaccat taacgtcctt acggtcaaaa tcataaaccc gataagtggt
      481 atcagatgac tgctgggttt ctaaaataag aattcccttg ccgatcgcat gcatggtgcc
      541 acttggaaca tagaaaaaat cgcctgcttt gactgggaca cgagtcagca aatcatccca
      601 agcgcctgct tcaatcatgg cacgaaggtc ttctttggac ttggcctgat ggccgtatac
      661 aatttcagaa ccctcttcgg cagaaataat ataccagcat tctgtcttgc ctaattctcc
      721 ttcatgttca cgtccataag catcatcagg atgaacttgg acacttagcc agtcattagc
      781 atctaaaatc ttagttaaca gtggaaaaac ttcttccttt ggattcccaa acaaggccgg
      841 ctcttgcgca tataatgtat ttaaaggttg tccttgataa cgtccattag taactgtcga
      901 aacaccatta ggatgagcag aaatagccca atactcacct gtggtgtcac ttgggatgtt
      961 gtaagcaaag acatctctca acttggtgcc accccaaatc ctgtcgtgca tggttgattt
     1021 tagaaataat ggttctgaca taatattcct cgcttctgat gttaatctct gtttattata
     1081 gcatgttcta gctgactgcg ctttctttta ctagacaagc aggcaaaaac agaccctatt
     1141 ttccttgtgc agccaacttg gccaaagcaa aatttcccag agtagcggag ccattatcag
     1201 caacagctgg agtaacaatg tagtctgtca aatcagggac tggcaaataa ccgcttaaaa
     1261 gggtagtgaa tttatcatgc acgcgcaaca ccatatgttc ttgcgccatg acacctccgc
     1321 caaaaacaat cacttgagga cggtaaagca tagttgcttg cagcgctgct tgggcaatgt
     1381 agaaggcttg aatgtcccaa acatcagctt cctgatcaag ccgttcacct ctcactcccg
     1441 ttctggcctc aatacttgga cctgctgcca tcccttccag acacccttta tgaaaagggc
     1501 aaacacctaa aaaccccttg gccatatcat caggatgggg catgacatag gtatgacccg
     1561 cttctgtatg acctaatccc ccaataaagt ggccatgttg aatagctccc gccccaatac
     1621 cagtacctat ggtgtaatag accaaacttt ccacaccagg acgagcaagc acctcaccat
     1681 aagcagagct attaacatct gttgtcacat caaaaggaat cttaaaagca gccgaaagtt
     1741 gtcctaacaa atccacatta gcccagcctg acttaggagt ggttgtgata taaccgtaag
     1801 tctctgacga cggatcaata tcaattggtc caaaagaacc aatcgtcatt ccagccaaat
     1861 ctgcctcaaa agctttaaaa taagcgatgg ttcgcgcgat ggtttcttct ggtgtggtgg
     1921 tcggaaattg tgttttatcc accactgtaa actcctcatc acccacggca cagacaaact
     1981 ttgtcccacc agcttcaatg cttccatata attttcccat gttttctcct ttttcttgtt
     2041 cttttttatc tttatgatga cacaggctct tatcaagaca gccatgtctc acggacaagt
     2101 gccactttct ggtagtctaa cgattattta gctttatgtc atcaaaacct ataaaagact
     2161 aaaaatctgg gactattcat ctcagatttt tagtcttttg gttaatcaat tccagcaaac
     2221 ctttatcata gtcacatttt gttaatttaa tctgaatgtt gctatctaag agagttgctt
     2281 tgtttatttt tttagcagct gccttttctc aatacaatct ttcaaaactc cagcattagc
     2341 attaatagca gttacatcaa aaatcttact gttcaaagaa gtttctaaag ccatctcttt
     2401 tatttttaac tcatcaagca tcttttgaga aaacttatct ttttgttgag atagaccttt
     2461 agcagtagtt actgttttca tgatagtgtc ggcgttaggt aacggataac ctaaaatttg
     2521 gagttcaggg actactggcg aactatatct atctccttta gtatcaaaga caactcgcca
     2581 atatttacta gtaatattat ttaatgtatt actgaatgca gtagctctct ctccttgtgc
     2641 actgtaagta tctacagtaa tccaatattt ttcatcatca aatttattgg gattttccaa
     2701 caaattatct agattataat ctttgatatt aaaaatttgt agacttgctt cctgaatagg
     2761 tttattggtt gtcttaggat ttcgggctga atcattgaag aaacgccaat actttattaa
     2821 tccatcttct ttcaatttaa atataatact ttgcttagaa tcccatccta aagagatatt
     2881 atcagtctca ctgcccagtt gcccatcaaa tacctttctt gcatttacag gatcagcgct
     2941 tcctccaata actgttgcgc cttctgccaa attaaccatc atggtttttt cgtcaccaac
     3001 aatcacttta gcagtatgaa cagcttttgt cttatctgct gggctaaaga agtcaacctt
     3061 ataggtctct tctttatcag ttgctagcgt tttgtcagta gtggttccca atgtggaatc
     3121 agttacttta acggtatagt tctcataaga aactttaaag ttattgtaat gatagtttga
     3181 atcaacaaag ctacgtccag caattttatg attttggtaa gccttatagt ctgcttcgct
     3241 attgattagg gttccttgat tcgtcacagt cccaaacaaa agctggcttt gcaaatcaac
     3301 tttttcattt gccactggta agcgcagact agttttccca taggtatctg ggtaatgccc
     3361 agttggtttt tgcttgtcaa atttcactgt ttgttcattg cttccaacat gattgctgac
     3421 agttgatagc atagtatcaa aaatttgtcg attttgtgtt cctggagcca aatcaagttt
     3481 gttgccagaa atatcaactt tttctaaaga cgttagagta gcggcatcaa gaccagccaa
     3541 ggtttcacgg tcaaaacctg acaaatctaa ttctttcaga ccagttaaac cagaaacctt
     3601 caaagatact ggtgggatag tagcaggttc ttctttgtta tcctttttat aggtttcaag
     3661 aactgtttcc aaggtatctt tgcctggctt catattagcg ggtaaaacag attggtcaag
     3721 ctttgtaatg cgagataagc caatcaagtc taattgagct aattttttaa atttatttag
     3781 accttctaaa ctttgaatcg ctggattatc caatcgtaat gtgccattga aacgttccaa
     3841 atcacctttt ctggttccaa cctgcgccat cacagcttct cgcaaagcct tatctgggaa
     3901 atctttctca tcaatcagat catacgactt atcttttagc ataactgtct ttaatgcctt
     3961 ggagacacta taatctgagt ggaagatgtt atcagtaatc tcatctacct gcgtttgact
     4021 acgcttatct tgctgagcaa ctttttcagg ttgatgagct acaccatcac ggtcaatagc
     4081 gtaggagaag atacctccct taaccccacc tgtcttaggt tgccaccttg cataccgttc
     4141 ggcacgcgtt ccagttatgt cagtgttaat tccatttgct ttgtcctcgt ccttgcgaga
     4201 attaatatca taccaaagat tgccgctgcc tgctctttcc tcatagaaag aaaaaccaat
     4261 catgtattgt tcaggacgaa tatacttgct ataaccttgc catcgttctt caggagtctc
     4321 ggtaactaac ctggtatcgt tttgaaactc accttgttct cctcttgcgc catagacttg
     4381 taccaataac aaatcaatat aaggagctcc tcgctcaatc aatgggtttt tatcagccat
     4441 gtaggtgcta tccataataa ataaccgcga tttatcagca ccttttggtc caattaattt
     4501 cccaatctct tcaaaaacat caatagatcg cttgagattt tcgtcactag ctttcccatt
     4561 cacttttgga atactatcat gttcaacatc cacatctaag ccatcaaggt tgtacttata
     4621 aacatattca tcaacaatag ctttggctaa agctttattt ccctctggtg tatttgggta
     4681 tttactggta tcttctgcaa taccactgtt atcacctcca gctaggaaac gccatggaat
     4741 ggtacgaatg acacgtgtcc cttgcttgtt taactttggc acatgtttga tggccaattc
     4801 tttccaaaaa aggctataat cttttgtcca atcgtggaaa ataaaggcta gatctacttc
     4861 tttaggaagc tctcccatcg agttaacttt gtctttttct gttggatctg atgttttgtc
     4921 atgccaagtt ctaaagtaac caccgtagag aggactatgt aacggtttca tcggtatttt
     4981 ctcaggaatt ttcattttgg caagttcttg agcttgttta tctgcctgct gagcttttgc
     5041 taatatctct ttgacctttt ctggtacttt ttcttttgaa agctcctctt taaattcttt
     5101 tttgctattc tctgacagat aatgcaagct atcgatagaa gataattctt tctgaacctg
     5161 aacagtcttc tcctccgctt ttacagtatt gagtgaatca tggtgggtcg ctaaggcagc
     5221 tcccatcaac gttgcagcac aaacacaccc tagtgttctt tttaccaaca aatgtttatc
     5281 catttggaca ctccttattt ttggtactaa gtcatggctt cccagttgat ataccatcta
     5341 tgtaagcgca ttcctatagt tcgccttaag tataacaaca ctttattaaa aaaaacaagg
     5401 tacaaagtat aggtaaaata acacaaattt aaggttttta ggcttttctc atttttttgc
     5461 caacctgcca tgaatggcag gacaaaagag ctgcttagtt agctcttttg tccttatttg
     5521 ataagtgcca cttgatcacc aatcaaaaca tgtccttgag caagaatgtc cacgctttga
     5581 tagtcagcgc tattggtcac aatcatcatg gtggtgtcat ctagtccagc ttctgcaatc
     5641 ttgctaggat caaagtgtcc aagaagatca ccttttttaa ccgcctgacc tactgctaca
     5701 agagattcaa agccatctcc tgccatcgac acggtgtcaa taccaatatg aagtaacact
     5761 tctgctcctt gacttgacgt tatagcatag gcatgacctg tctcaaaaac aatggctact
     5821 ttcccatcaa ctggcgagta gagggccttg ccttctggct taattgctaa gccttgaccc
     5881 atagcacctg atgaaaaaac agggtctgaa acagctgcta aatctacaac tattccattc
     5941 aaaggactat ataaagtttc ctctgctaag gctggctgat tagctgtttg atcaacttcg
     6001 acagctggta acggaagggg ttctctatct tgataacccc aagtataagc aattgcaaag
     6061 gctaccccaa gaccgacaag catagtcaca aggtattgta ataattggcc attcaagtaa
     6121 aggagagttc ctggtaagac cgtaatccca aaaccagttc ctgcaatgcc aaagagtcca
     6181 gcgacccaac cacctaaggc accaccaata agacctgaaa caaagacttt tggataacgg
     6241 agattgaccc caaaaatagt tggttcagta atccctaaaa gagctgataa ggtcgatgga
     6301 aaagccaaac cttttaattt tggtgatttg gttttaacag caacagctaa ggtagctcca
     6361 gcttgagcag ctgttgctgc tgttagataa gcattgaaag gatcttttcc ggtattggca
     6421 atcagctgcg cttctaggaa gttaaagata tggtgaatac cagtaacgac gatcaactgt
     6481 tggataccac caacaataag accagcaatg ccaaacggca aatgcaagac ggcctgtgtc
     6541 ccagccagaa caaggttttc aagagaatgg aaaactggtc caatcacaaa tagtcccaag
     6601 gtactcataa tagcaaacgt taaaaacggt gtgaccaata agtctaaagc ttctggaacc
     6661 tttttgtgca accatttctc caacttagct cctaccagac caacaaagaa ggcaggtaaa
     6721 acggtacctt gataaccaac aacaggaaca aatccaaaga aggttagcgg cttaacatct
     6781 ccaccagagg caactaccca ggcgtttggc aattcattgg acaccaacat caagcctaaa
     6841 acaataccga taataggatt acccccaaag accctaaagg ctgaccaagc caccaaagct
     6901 ggcaagtaga caaaggctgt atccgttaga atacgagtgt acatgagaaa attttccccg
     6961 tactcatgca ccccaaataa atccataata gctggctggg tcaccaaacc acgaaccccc
     7021 ataaagagac ccgttgctac aatagctgga ataatgggaa caaacacatc tccaaacgta
     7081 cgaatcgccc gttggaagat attgccttgt ttgcctgctt ctgctttttg ctcactggtt
     7141 gatgacgtgg gtaaaccaag agcaacaact tcgtcataaa tgttattaac ggtaccagtt
     7201 ccaaaaatca tctgatattg accagagtta aagaatgctc ctttaacctt gtcaatagct
     7261 tctgcttttt ccttatcaat ctttccttca tcataaacca tcacgcgaag gcgagttgca
     7321 cagtgggcaa cacttctcac attttctcgg ccacctaaag cctcaatcac ttcagctgca
     7381 atctgacgat tatccatgcc taaaagtctc ctttttcatt tggtgttagt cccccatcca
     7441 ttctgccagc tttgtggcta agaatgtgca ggaccaacgc tagtgaatcc gcttcacttc
     7501 ttgactatca ttttatcact aatatttttt atgtcaagcg tttaacatat ttttgtttta
     7561 tatgacttaa attcttgatt tttaaacaga aaacgtttag tatattcttg aagacgacta
     7621 taaaacaagg agattttgat ggatctacca caagctattc gctaccgccc ttacaaaggg
     7681 tggagttcaa aagactacca agctattact gaaaaaatgg cccaatcccc atggcacagc
     7741 caatttcatg tcgaacctaa gacaggatta ctcaatgacc ccaatggttt ttcttatttc
     7801 aacggtcgct accatctttt ttatcaaaac tggccttatg gggctgcgca tggtctgaaa
     7861 caatgggtac acatgacatc cacagacctc gtccatttta cggaaacaag gagccgcctt
     7921 ctgccagacc acgctcacga tagtcatggg gcttactcag gttctgccta tgctattgat
     7981 gacaagctct tcctctttta cactggtaat gttcgcgatg ccaattgggt cagaacacca
     8041 ttacaggttg gcgcatggat ggataaacaa ggaaatattt ccaaaatacc acaggttttg
     8101 attgaacagc ccgatgatgt tacagaacat tttcgggatc ctcagctttt ttcttatcaa
     8161 ggccaattct atgctattat tggcgcccaa ggtttagatg gcaaaggaaa aatcaaactt
     8221 tacaaagctg tggacaatca tgtggacaac tggcgattta tagccgattt agactttgac
     8281 gattctggta cggaatacat gattgaatgc cccaaccttg tgtttgtcga tgacaagcct
     8341 gttttgattt tcagcccaca aggactggct aaagctgatt tagattatca aaatatctac
     8401 cccaatacct ataaaatttt tgaaagcttc aatccagaaa ctggccaatt gctgggtggg
     8461 ggggcccttc aaaatcttga ctttgggttt gaggcttatg ctactcaagc ctttaatgct
     8521 ccagatggca gggctttagc tgtatcatgg attgggctac cagatattga ttatccgaca
     8581 gatcgttatg actatcaagg agctcttagc ttagtaaaag aattaaggat tagagacgga
     8641 attctctatc aagcacctgt ttcagcccta aaagaccttc gaggaccggc agaattattc
     8701 cataataaaa tagacagttc caactgttat gaattggaat tgacgattcc aggccaaaaa
     8761 aagcttgacc tgctcctatt tgccgaccaa aaagggaatg gcctaagatt gaaagtggat
     8821 acaacaaaag gacagttaag cattgaccga agtcgggcag gggttcaata tgcccaagac
     8881 tatggtacgg tgcgctcttg ccaaatccca caaagccatg ttacacttaa tgtctatgtg
     8941 gacaattcca ttcttgaaat ctttattaac caagggcaaa aagtcctaac gagtcgtgtt
     9001 ttcccaaccc aaggacaaac aggtatccaa gtagtagaag gacaagcttt tggacattat
     9061 tatgaaatga ggtattaggc aagtggtctc aaaattaaca gacgtggcag ccttggcggg
     9121 tgtcagtcca acaactgttt cgcgagtaat caacaaaaaa ggctaccttt cccaaaaaac
     9181 agtgaataag gtgaataagg ccatgcgtga attgggctac aagcctaaca atctcgctag
     9241 aagtttgcaa ggtaaatcaa cccaactcat tgggcttatc ttccccaaca ttagcaatat
     9301 cttttacgct gaattaattg aacatttgga aattgaattg tttaaacaag gctacaaaac
     9361 tattatttgc aatagtgaac ataatcccgt caaagaacgc gaatacttag aaatgcttgc
     9421 ggccaatcaa gtggacggca ttatttcttc cagtcataat ttgggaattg aggattatga
     9481 gcgtgtcgaa gctcctattg tagcttttga ccgtaatctg gcgccaaata tcccggttat
     9541 ttcttcagat aattttgaag gtggtaaatt agccgcacaa actttgcaaa aacacggttg
     9601 tcaaaacatt gtcatgatta caggtaatga caattctgat tcgcccacag ggttgcgcca
     9661 gctagggttt aactaccagc tcaaacgaag tgcagaaatc atcaaattac caaataacct
     9721 atctcctgtt agacgcgaaa tggaaattaa atccattttg gcaacccgaa aacctgatgg
     9781 ccttttcgtt tctgatgatt taactgctat cctcattatg aaagtagcca aacaacttca
     9841 cattactatt ccagaggata tgaaagtcat aggttatgat ggaacgacat ttatccagca
     9901 atatgttcct caattagcga ccattcgtca acctattgat gagattgcta aattgagtgt
     9961 cgaaatactc attaaaaaaa ttaaaaaaga aaaaaccagt aaagactata ttttaccgat
    10021 tacgctactt ccaggagcaa gtatttaaac aaagcataac caatcactaa ttactctaaa
    10081 agacaaacaa gcatactctt tctagatgcg agagtatgct tgtttgtctt ttaatattcg
    10141 tacataaatt gaaaaaatcg gatacaatcc taagattgct ccgacttatt atgatttatt
    10201 tgctgaagga gcttccgaga catattggct aagtaagcca ttaataaatt tagcagaggt
    10261 ttcatcagaa tattttttag ctacttcaat gatttcgttt agtgcaacac gatctggtgt
    10321 ttcgtcaaaa tacttgattt caaaaagacc tagccgtaat aacgttttgt ctgttagtgt
    10381 caagcgttct aacgaccaac cttttttcaa atgagttgat atcaagttat ccaactcttc
    10441 tttatgatta ttgacacccg tcacaagact taataaaaaa atcggcagct ccaatacttg
    10501 agcgtcctcc cctgttactt tatcataacc ataggcaaac tgagaagctg ccaataactc
    10561 agctcccgtc tctatgttaa ataaagcctg aaaggcacgt tcacgcaaat ctcttcttga
    10621 attttgaaag ctgttagtca tccaagaaat cctcatcaaa aagtgacttc aaatctggtt
    10681 ttggtgtctt ttccgcaaca ataccttcaa catggatatt aactgcagaa ataggcactt
    10741 ctgccatatc gtacacagca gatttgactg ttttttgaat attcatagat acagtcggga
    10801 ccttgactcc atattgcaag taaacataaa tatctgctgt aacacttcca tcttcttctg
    10861 tctggagata aaccccttta ccaagacttg ctttgttaaa gctatctgcc attttcttgt
    10921 tatggagtga gtggacgccc tcaacttgtg tcgtagcaat ccccgtaata acctcaagca
    10981 ctcgtggtga aatgacgatt tcaccgatat attcagttgt catagcattt cctttctctt
    11041 ttttagacta atctgttttg acaaaggatt aagcacgaga aacgtaagta ccttctgcag
    11101 tgttaatgat tagtttttgg ccagcttcga taaagtctgg aacgttaaca acaagtcctg
    11161 tctcaagagt tgcaggtttc cctgaacccg tcactgtcgc tcctttaata gatggttgtg
    11221 tttccgcaac ggtcaattca acagttgttg gaaccgttac cccaatcact tcacttccat
    11281 aaaattggat tttcacgtct gagttttcaa gaatgtaaag caattcttgc tcaacgttag
    11341 caactggaat ttcgtactga tcataagtgt cagtgttcat gaagtaagca gtgtcatcca
    11401 ttttgtatag gtattgtgct gggacagttt caatgatggc ttgctcaaat ttttcatctg
    11461 ggcggtaagt tgtgtcaaaa gtagaacctg tacgcacatc acgtagtttc atacgcatga
    11521 tagtgtttcc tttacctggt ttgtggtggc tagcttcaag gacacggatt aattttcctt
    11581 ctgcttcaaa tgtcatacct gctttaagct tacttgcttc aatcattatt attacctctt
    11641 actaaaatat ttatcacttc attttaccac aaaagtggcc ttggctcaaa tcttttatga
    11701 ccgtcctttt aggtacactt tctattgttc cttatcgcct cctaaaacaa tttgaggcac
    11761 atcatgttgc acataggcaa cccctttttt ctccatcagt tcaatggcaa aggggtgcgg
    11821 acggtaatgt gctttatagg taatctttgt aatccccgcc tgcaaaagcg ccttagtgca
    11881 gttaatacaa ggaaaatgag tcacgtaaat ttcagttccg tcagtcgaaa ttccttcttt
    11941 cgcacattga atcaaagcat tcatttcagc atgaacagtg cgaatacaat gaccgtcttc
    12001 catataatga cccgcttcat tgcagttatc cgtagcagaa actccgccat tgtaacctgt
    12061 ggcaataatg cggttatcct ttaccaaaac agctcccaca aaggcgcgat cacaggtaga
    12121 gcgcttggaa atcagctctg cattggccat aaaatagtct tgccatgata aacgatttgt
    12181 cattgcttct cccctaatcc tttcctgaac cattctttta caatacaatt aattctttgg
    12241 gtgccaaggt caagacttga caaccagttt ttgtgataac caagtcgtct tcgatacgga
    12301 caccatattt gttatccaaa tagatacctg gctcgtctgt gaccaccatt ccagcttgga
    12361 gaagttgctc agatttccca aaaaatggat tctcatggat gtcaagcccg ataccatgac
    12421 caatgccatg tgtgaagtga ctaccataac cagcctcagt gatgagttgg cgcggaatac
    12481 cgtcaaagtc actataagtc atgccagcgc tagctttagc aattaaagcc ttattagcag
    12541 caagaacaag agcataaatc tcacgttctt catcagtaac ttggccaata tgaatggtcc
    12601 tcgtcatatc actaacatag tgattgtagt aacacccaaa gtccatggtc aagctctctt
    12661 tattctggat aaccttgtca ctggcgcgtc catgaggcat ggcagagcga tagcctgaag
    12721 ctacaatgat atcaaatgat gtgccgctgg caccatactg acgcatgcga aaatctaaaa
    12781 aattagccag gtcacgttca gtggttgtcc ctggtttaat aaaatcaaga gcatcttcaa
    12841 atgctttatc tgagatcgag cacgctttag caatggtctc gatttcagag gcgtccttaa
    12901 taagacgtaa atgctccaca aaacctgact gagcaagcaa ggttattcct gacagttctg
    12961 cttgcatggc ctgataaaaa gaaaacgata cctggtcctc aaaaccaagg caatctattt
    13021 gatcagcctc taacaattct gccacaacct taagcggcgt gcggctttcg ataatatcaa
    13081 atccctcaac actagcttta gcaagcaagg tataacgtga atctgtgatc aaaacacgac
    13141 gtttggccgt tatcaaaaca gttgctgcag ttccagaaaa acctgtcaag taataactat
    13201 tggttaaatg ggtgaccaga agagcctcta gccccttctc taccatctgc cttaggcagt
    13261 gacctaatcg ttgctctaaa aatcctgaca tcgcaaactc ctttggtaac ttttgagaat
    13321 attgtagcat gaaaaaacta ctttaagttt accatgattt gagagcattt aaaagattaa
    13381 aaaggagctc aaacgaactc ctaatcctat tgttgtagtt ttactttcaa ataatgacca
    13441 gtatagcttt ctttaacttg agctacctct tctggcgtcc ccgtggcaac aatctgacca
    13501 cctccgacac caccttctgg tcctaagtca ataatatggt cagcagattt gataacgtcc
    13561 aaattatgct caatcacaag aaccgtatta ccatcgtcta caaagcgttc caaaactttt
    13621 aatagccttg caatatcatc tgtgtgtaaa ccagtcgttg gctcatctag gatatacaag
    13681 ctcttacctg tcgagcgttt gtgcaattca ctagctaatt tcatccgctg cgcttctcct
    13741 ccagatagag tagtagctgg ttgacccaag gtcacataac ccaaaccaac atccttaatg
    13801 gtttgaattt ttcgggcaat tttagggata gcagagaaaa ataccaaggc atcgtcgaca
    13861 gtcatgtcaa gcacttcagc aatatttttt tctttataat gcacctcaag cgtctcagaa
    13921 ttataccgtc tgccgtggca aacctcacaa ggcacataaa catctggcaa aaagtgcatt
    13981 tcgattttga taatcccatc acctgaacaa gcctcacaac gcccaccttt gacattaaaa
    14041 gagaaacggc cttttttgta gccacgaatc ttagcttcgt tggttcgggc aaacaagtct
    14101 cgaatatcat caaagacacc cgtataggtg gctggatttg accgtggcgt ccttccaatc
    14161 ggactttggt caatgtcaat caagcgttca atatgttcaa taccagaaat agagtgatat
    14221 ttaccaggct tatcagcatt acggtttaat ttttgggcga cagccttttt caaaatacta
    14281 ttaaccaagg ttgatttccc tgagcctgat acccctgtga ccgcaataaa tttacccagt
    14341 gggaatctca cgtcgaggct ttgaagatta ttctgcgctg ctccttttat ttcaatgaat
    14401 cggccattac cagaacgacg ctctaatggc actggaatga attttttacc agacaaatat
    14461 tgacccgtaa tggatttttt attcttagcc acttgtttcg gcgttccaga ggcaataatt
    14521 tctccaccga actcacctgc cccaggaccc acatcaatca gccagtctgc ctgcatcatg
    14581 gtgtcttcat cgtgttctac cacaattaag gtattaccca aatcacgcat ttttttcagg
    14641 ctttcgatca aacggtcatt gtctctttgg tgcaatccaa tagaaggctc atccaagata
    14701 tagagcaccc ctgataagtt agaaccaatt tgtgttgcta acctgattcg ttgactttcc
    14761 ccacctgata aagtcccagc agcacgtgat aaggtcagat aattcagtcc cacattattt
    14821 aagaaggtca ggcggtcatg aatttctttg acaatcggtt tagcaatggt actttcattt
    14881 tctgtgagtt ccagttcttc caacaactgc aagtggtcgg caatcgataa ttctgaaatt
    14941 tgaccaatat gaggtccttc ttcgccaccc acatgcacac acaaggcttg gtcattcaaa
    15001 cggtaaccat gacaagtcgc acaggtcaat tcgttcatat aaccacgcat cacattgcgc
    15061 gtataatcac tattagtttc gtgataacgg cgattaacat tagtcacaac accttcaaaa
    15121 ggaatgtcaa tgttacgctc accaccaaaa tcattcacat agtgaaaatg aaattctcta
    15181 tcccctgaac cataaagaac taaatctctt tcttcctcag tcaaggcctc aaaaggtgta
    15241 tccatatcca ccccaaaact cgccatagct tgctcaagca tggttgggta gtaattggag
    15301 gaaataggat tccaaggagc caatgctccc tctttcaaag acttacttgg gtcaggaaca
    15361 accaagtcca aatccacttc caacttaatg cctagcccat cacaggtcgg acaagagccg
    15421 aacggcgcat taaaagagaa gagtcttggt tctaattcag ggaccgtaaa cccacagaca
    15481 ggacaggaat aatgctcaga aaagagcagt tcattgccat ccatagtgtc aatcataagg
    15541 tagccatctc ccagccttaa agctgcttca accgaatcaa ataaacggct acgaatacca
    15601 tccttattaa ccagacgatc aataaccacc tcgatgttgt gcatcttact ttttgacagc
    15661 tccggcactt ctgtcacgtc aaaaatatcc ccgtcaaccc gcacacggac ataaccatct
    15721 ttttgaattt tctcaaaaat ggttttgtgt tgaccttttt tccggcgaac aataggcgct
    15781 aaaatctgca tgcgtgtccg ttcagggagg gctaagacct gctctacaat ttgttctgca
    15841 gaagatgctg taatggcccc atgcccatta atacagtaag gtgtgcccac acgcgcatat
    15901 agtaaacgta aataatcatt gatttcagtc accgtaccaa ccgttgagcg ggggttctta
    15961 ctggtagttt tttgatcaat ggaaatagca gggctaagac cgtcaatgga atccacatct
    16021 ggtttttcca tattacccaa gaactgtcta gcataagctg ataaactttc tacgtaacga
    16081 cgttgccctt ccgcataaat agtatcaaag gctagactag attttcctga ccctgataac
    16141 cctgtcacga caactaattt gtctcgtgga atttccacgt caatattttt taaattgtgg
    16201 gctcttgccc catgaattat tattttattt tgcatcttga atgtgcctaa aggcaccctc
    16261 ctcatcgagc tttcttatat tataacaaaa aagaacctta atatggtatc atttgctatc
    16321 attgcccaat cacttgataa atcaacattt tacaacctta cattatctag tcaattacac
    16381 tgatttttaa aataacgtag taattttccg ctggggagca tctgattttg gacttggaaa
    16441 agtctttttt atttgtctaa ttccaccatc acttcttcca ctatctcctc ggtcacaact
    16501 tctccatttt ttactttctc atgtggcaaa acataatcaa aaatctgtcc gtttttacgc
    16561 acgatcataa ctgtgtctcc tgtgatatat ccacggtcaa tcgcttgttt aaactcgtcg
    16621 tatgttagca tttttaccct cctacttatt tattcgtatt ttacaggaaa taatataatt
    16681 aaatttaaag gtcgtttaaa tttaattaac atcttttttg ttacaaacta aaatattgat
    16741 tgttagcgaa tattaaataa aaagaaattt tagcgtaata ttattgataa attaatttta
    16801 ttaattttaa gtttttttaa tttaaagtga tataattaac ctgtaaataa taaaaggagg
    16861 acatggatat gtctaaagca aatcgtcgta tttggcaagg tttagctgtc attttaatag
    16921 ctataataac cactttcaca acaagtactg ccacggcagc caaaaaaatt agaaatttcc
    16981 ctactaccac ggagattttg tcaggaacga aggcgactga agcacctgga atcttgccat
    17041 ttactggtag ctacaaatta gttttgggtg accttgataa tctgcgaaga ccaaccttcg
    17101 cacacataca gcttaaagat caggatgagc ctaaaattca gcgaaaagga cttaaattca
    17161 atcctccagg ctggcataac tacaagctga ctgatgctaa tgggaaaaca acttggttaa
    17221 tggatcgcgg ccatctggtt ggctaccaat ttagtggttt aaatgacgaa cctaaaaatc
    17281 tagttacaat gacaaaatac cttaataccg gttttagtga cagaaatcct ttaggaatgc
    17341 tctattacga aaacagatta gacagttggt tagctttaca tcctaacttc tggctagact
    17401 ataaagttac tcccatttat catgaaaatg agttagtccc tcgccaagta attctacaat
    17461 atgttggaat tgatgaagat ggaaatctac ttcaaattaa gttaggtggt gaaaaagaaa
    17521 gtgtagataa ctacggcgta acatcagtta cactagacaa cgtatctcct ttagctgaat
    17581 tggattacca aacaggaatg atgctagatt caactcaaaa cgaagaagat agtaacgtag
    17641 aaaccgaaga gtttgaagaa gccgcttaac ataaattgac tgcactataa aaaacaaccg
    17701 cccagaaatt aatctgagtg gttggttttt ttatttcagt ttttctttga cagcatctac
    17761 tgccccttca actgcttctt tagcatcatc tgctagttct ttacctttgg caattgtttt
    17821 ttcaacaaat ccttttgcct ctaactcttt atcaccagtt agctttcctg caccttcttt
    17881 aaggctacct gaagcttgtt caacttttgc ttttagtttt tcttctgaca taatatgcct
    17941 cctttatttt attctatggt aacactttga gcatctataa gcaaacaaaa aaaccagccg
    18001 catggactgg ggaaaattag cttttatgaa agatttagga ttatgaatat atattagcac
    18061 acaacaaata aaaaagcaag agccgctagt gtcaggcagt tcttgctaaa aatttctatt
    18121 tttttgaatt tgtaaaagca gtgcacttta ttccattaat cattgcctta acagaatcat
    18181 aatctttaaa acctaaaagc tttgccctac tgtcatcttc tttacaaaga gccttcaaac
    18241 tagactgtat ttttctccat tgatatttgg agttaatagt atttacaaga tagactacaa
    18301 tagcaataat aacggataac ttattagaag gtttagtcac gttatgttta atttttactg
    18361 tatcaatata atttctccat tctgaacgaa gtttaggctt tgttgtgatt tgaatatcca
    18421 gtacatttga attatgagca catacatttc ttatgaaatt caaacattta agccacgaaa
    18481 caagttcttc tggtgtacaa ctgtaatatt gacaaatctg tttaatattc ttctcgctca
    18541 tgattgttaa gattgaaacg atgtcaccaa acatcaataa atcaatagca agccacactg
    18601 ttgggaatcc atctggatca aggttaattg atttttgtaa ctcagttagt tgagattttc
    18661 ttacagtatt caataaattc tttttaatcc taaattgtct tttttcaata tcatattttg
    18721 taaacttatt cctattagcc catgaagaga aatttaaata tccaaatgct ccgtatctat
    18781 cccccaaaac aaaagaaatt tttgttttaa tagacacttc aattttttca atagcgtgca
    18841 gtagatagat tcttaagttt ttatcctgat aatatcttgc caaaacttct gcaaactcaa
    18901 tattatcata taaaatatct ttctcctcac catcttgtcg ctttatttca agtggttttg
    18961 caaattcttt aattctataa taactgatgt gtttgatttt ctctacatca tcagctttaa
    19021 caattaatcc acgtttttca aataacctaa tttgatcttc ccatgtcaaa gctaaaggtt
    19081 gtttcataac tctcctaacg atataaaaaa agccccatat cagaacgtat ctgcctttaa
    19141 aggaatgggg ggtttgtctt gttaagataa ttatactttt tttaaaaata atgtcaagac
    19201 acaagatcgt gtcttgaaac ttataaattc aagcgaacac aacatattga atgattttat
    19261 ataaaaatac attttttaac acaatatatt gtaaaaattt tgttgcattc actattaata
    19321 acaaaaacag cccccgcaaa gcgagggcat ttgtcttatc ttaaggagct ttacctccta
    19381 tctaaaagta ccaaaattag tcacacgtcg gccattttgt gagtttccga ccgcaacgta
    19441 tcgtctaaca ccagtcacac tgatatatgt tacccaaata tagccgtctg agtcaatcca
    19501 accatcatag ttaaattcca tgttttcacc ataagttgcc acaatttctg catctagacg
    19561 aggtgcagaa cggacattta aagcagcaac acgaacggta aaagtacctg tttcagggtt
    19621 aactacataa gtaccatctg actgtgcaac cactggagca cttggttcta tttcttgcac
    19681 cggtgtatta tcgtaaggag ggtaaaacca acccaaaata tatccagtac catcttcaaa
    19741 cggacgatcc acataacgtg ctggtccacc aatataaagg gcgtcagcat taccatctac
    19801 gttttgctcg atgttatgca gaacatatcc gtctgatgta acaatgacta acccagtatg
    19861 accatagccg tgagcgtaag ttaccatcac aaagatagcc ccagctcgtg gattaactcc
    19921 aggagcattg tagaccactt ccattccttg ggcggctgca ctatctagta agtcaatagc
    19981 atttccccaa agggcaatgc caaaatattt tgtcgtgatc cagtttggca agtccacgca
    20041 ctgcgtaccg taaacattat cgaggtcaac cccttgacca gtgtctgcca atcccttggc
    20101 aaaggataat acttcatcta aagttgccat atcagttact tcctttcttc aaaaaacggg
    20161 cttaaaatca aagcaaccac agataatggc acatacagta ttgcgattgc tagtattaac
    20221 gctaatcgtg tgattgctcg catggctcct cctatttttt gggctcatgg taagtcaatg
    20281 cttgctcact
//
LOCUS       DAXMQE010000033        19517 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.033, whole genome shotgun sequence.
ACCESSION   DAXMQE010000033 DAXMQE010000000
VERSION     DAXMQE010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19517)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19517)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19517
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.033"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            <1..383
                     /locus_tag="ACF4ZO_001428"
     CDS             <1..383
                     /locus_tag="ACF4ZO_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HFD5486955.1"
                     /translation="TKSGLPLGILVNSGAHNDSLLLQLGQLFEKANRFHILTAGKKGL
                     PETPTHEHNLSTQSENKQGVAIPVTYQTKGFTTGPTKGQNGLVTLPQTGDGQSKGVLL
                     SSYISLFLGTLFLAGSFWSNKLKD"
     gene            568..2325
                     /gene="pabB"
                     /locus_tag="ACF4ZO_001429"
     CDS             568..2325
                     /gene="pabB"
                     /locus_tag="ACF4ZO_001429"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046820 - 4-amino-4-deoxychorismate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0008153 - para-aminobenzoic acid
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HFD5486956.1"
                     /translation="MHRKTIIDFKELGRRYLFDEPLVELVAKSLDQVGPVIEKVQHYQ
                     QLGYYVVGYLSYETAAFFDNALQTHNNRLGNEYLAYFTVHKTCQKKDLPLDYDSITIP
                     NQWVSATQKEAYQKAIESIHREMQQGNTYQVNYTIQLTQELNAADSFAIYNKLVVEQA
                     AGYNAYIAHDEFAVISASPELFFKQEGNQLTTRPMKGTTKRGVNTWLDQQEHDWLQAD
                     GKNRSENMMIVDLLRNDMGKICQIGSVCVDRLCEVERYSTVWQMTSTIVGDLKADCDL
                     IDILTALFPCGSITGAPKVSTMAIITSLEPKPRGIYCGSIGICLPDGRRFFNVPIRTI
                     QLSHDQATYGVGGGITWQSKWEDEYEEVHQKTAFLYRHKQIFDLKTTAKVEHQKIAFL
                     EQHLNRLKEAATYFAYPYDEKALQKQLSTYLENKNNAAYRLMIRLSKDGKISLSDQPL
                     EPLSADFLTAQLSLQKKDVTASPFTYFKTSYRPHIEQKSYEQLFYNQAGQLLETSIGN
                     LFVQLGQTLYTPPVAVGILPGLFRQELLATGQAQEKEVTLADLKEASAIFGGNAVRGL
                     YPLNLELTHLDALLAKSQA"
     gene            2358..2924
                     /locus_tag="ACF4ZO_001430"
     CDS             2358..2924
                     /locus_tag="ACF4ZO_001430"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004049 - anthranilate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046820 - 4-amino-4-deoxychorismate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HFD5486957.1"
                     /translation="MILLIDNYDSFTYNLAQYLSEFDETIVLYNQDPNLYDMAKKANA
                     LVLSPGPGWPKEANQMPKLIQDFYQTKPILGVCLGHQAIAETLGGTLRLAKRVMHGRQ
                     STIETQGPASLFRSLPQEITVMRYHSIVVDQLPKGFSVTARDCDDQEIMAFEHHTLPL
                     FGLQFHPESIGTPDGMTMIANFIAAIPR"
     gene            2957..4225
                     /locus_tag="ACF4ZO_001431"
     CDS             2957..4225
                     /locus_tag="ACF4ZO_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HFD5486958.1"
                     /translation="MPDHLALRMRPKTISEVIGQKHLVGEGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTRYAFRTFNATIDSKKRLQEITEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLENGTIIMIGATTENPFFSVTPAIRSRVQIFELEPLSNEDIKTAIQ
                     LAISDKERGFPFLVTIDDEALDFIVTATNGDLRSAYNSLDLAVMSTKPDSDGKRHITL
                     DTVENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVNASLHYAARLVEAGDLPSLAR
                     RLTIIAYEDIGLANPDAQVHTVTALDAAQRIGFPEARILIANVVIDLALSPKSNSAYL
                     AMDAALADLRTSGNLPIPRHLRDGHYAGSKDLGNAKDYLYPHAYPEKWVKQQYLPDKL
                     VGHHYFEANETGKYERALGSNKERIDKLSD"
     gene            4314..4510
                     /gene="ssrS"
                     /locus_tag="ACF4ZO_001432"
     ncRNA           4314..4510
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="ACF4ZO_001432"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            4511..4583
                     /locus_tag="ACF4ZO_001433"
     tRNA            4511..4583
                     /locus_tag="ACF4ZO_001433"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4544..4546,aa:Lys,seq:ctt)
     gene            4724..5164
                     /locus_tag="ACF4ZO_001434"
     CDS             4724..5164
                     /locus_tag="ACF4ZO_001434"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFD5486959.1"
                     /translation="MKIIEYKGNYRDDLIFMVLEAKNALRRIPSINPDLLTIETSYLE
                     KGDCFWLAVNEESRVIGSIAYSSIPKTNEVFLHRLFIKPSLKHQGIGSQLLTFAEDYL
                     RKIGKSHVRIHLGQPKEQWFESYRFYPKHGYQFYDDTHLIKKLI"
     gene            5219..5725
                     /locus_tag="ACF4ZO_001435"
     CDS             5219..5725
                     /locus_tag="ACF4ZO_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HFD5486960.1"
                     /translation="MKIAIIGHSGSGKSTLARFLGQHYHCEVFHLDQLHFSSNWQERS
                     DHDMIADLSTCLLKQDWIIEGNYANCLYEERMSEADYIIYVNFSRFHCVYRAFKRYLN
                     YRRKTRPDMADNCQEKFDVAFVKWILLGGRSRNQLKKYQSVIQKYPHKTIVLTNQKQL
                     SHYMNTIN"
     gene            5974..6675
                     /locus_tag="ACF4ZO_001436"
     CDS             5974..6675
                     /locus_tag="ACF4ZO_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exotoxin beta-grasp domain-containing protein"
                     /protein_id="HFD5486961.1"
                     /translation="MKKTKLIFSLTSIFIAIISRPVFGLEVDNNSLLRNIYSTIVYEY
                     SDTVIDFKTSHNLVTKKLDVRDARDFFINSEMDEYAANDFKAGDRIAVFSVPFDWNYL
                     SKGKVTAYTYGGITPYQKTSIPKNIPVNLWINRKQIPVPYNQISTNKTTVTAQEIDLK
                     VRKFLIAQHQLYSSGSNYKSGKLVFHTNDNSDKYSLDLFYTGYRDKESIFKVYKDNKS
                     FNIDKIGHLDIEIDS"
     gene            7404..9032
                     /locus_tag="ACF4ZO_001437"
     CDS             7404..9032
                     /locus_tag="ACF4ZO_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFD5486962.1"
                     /translation="MSKYLKYFSIITLFLTGLILVACQQQKPQTKERQRKQRPKDELV
                     VSMGAKLPHEFDPKDRYGVHNEGNITHSTLLKRSPELDIKGELAKTYHLSEDGLTWSF
                     DLHDDFKFSNGEPVTADDVKFTYDMLKADGKAWDLTFIKNVEVVGKNQVNIHLTEAHS
                     TFTAQLTEIPIVPKKHYNDKYKSNPIGSGPYMVKEYKAGEQAIFVRNPYWHGKKPYFK
                     KWTWVLLDENTALAALESGDVDMIYATPELASKKVKGTRLLDIPSNDVRGLSLPYVKK
                     GVITDSPDGYPVGNDVTSDPAIRKALTIGLNRQKVLDTVLNGYGKPAYSIIDKTPFWN
                     PKTAIKDNKVAKAKQLLTKAGWKEQADGSRKKGDLDAAFDLYYPTNDQLRANLAVEVA
                     EQAKALGITIKLKASNWDEMATKSHDSALLYAGGRHHAQQFYESHHPSLAGKGWTNIT
                     FYNNPTVTKYLDKAMTSSDLDKANEYWKLAQWDGKTGASTLGDLPNVWLVSLNHTYIG
                     DKRINVGKQGIHSHGHDWSLLTNIAEWTWDESTK"
     gene            9145..10122
                     /locus_tag="ACF4ZO_001438"
     CDS             9145..10122
                     /locus_tag="ACF4ZO_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD5486963.1"
                     /translation="MKRTTIIIIWKIIRCITLIFGVSVLTFVLLKQSPVDPVMASVNY
                     DTSLTPAQYKAIAHHYGLDKPALVQYFIWLKNVIQGHLGTSLVYRQPVSDIIRSRAGA
                     SFILMGLSWILSGLIGFILGTLSAFHQGKLLDRVVRWFSYLQISVPTFWIGLIFLLIF
                     SVQLGWFPIGISSPIGTLSQDITLADRIKHLMLPVFTLSILGIANVTLHTRTKMMSVL
                     SSEYVLFARARGETQWQIFKNHCLRNAIVPAITLHFSYFGELFGGSVLAEQVFSYPGL
                     GSTLTEAGLKSDTPLLLAIVMIGTLFVFAGNLIADILNSIINPQLRRKV"
     gene            10119..10940
                     /locus_tag="ACF4ZO_001439"
     CDS             10119..10940
                     /locus_tag="ACF4ZO_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015631767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD5486964.1"
                     /translation="MILKRRTMVLWQLGIAISLILSILALNLYFYRTPLETNAALRNL
                     APSLNHLFGTDGLGRDMFVRTIKGLYFSLQVGLLGALMGVFLATVFGVLAGLGNSLID
                     KIIAWLVDLFIGMPHLIFMILISFVVGKGAQGVIIATAVTHWPSLARLIRNEVYDLKN
                     KAFVQLSKSMGKTPYYIVRHHILPLIASQIFIGFILLFPHVILHEASMTFLGFGLSAE
                     QPSVGIILSEAAKHISLGNWWLVIFPGLYLILVVNAFDTIGESLKKLFYPQTDHF"
     gene            10952..11755
                     /locus_tag="ACF4ZO_001440"
     CDS             10952..11755
                     /locus_tag="ACF4ZO_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFD5486965.1"
                     /translation="MTETLLSIKDLSITFTQYGRFLKPFQSTPIQALNLEVKKGELLA
                     IIGASGSGKSLLAHAIMDILPKNAAVTGDMIYRGQSLTSKRIKQLRGKEMTLIPQSVN
                     YLDPSMKVKHQVRLGISENAKATQEGLFQQFGLKESDGDLYPFQLSGGMLRRVLFTTC
                     ISDTVSLIIADEPTPGLHPDALQMVLDQLRSFADKGISVIFITHDIVAASQIADRITI
                     FKEGKAIETAPASFFSGGGEQLQTEFARRLWRTLPQQDFLKGVTHDLRG"
     gene            11739..12365
                     /locus_tag="ACF4ZO_001441"
     CDS             11739..12365
                     /locus_tag="ACF4ZO_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD5486966.1"
                     /translation="MTLEAKKLGFYHKKDQWLFKEIDLEVAPGQILGIFGPSGCGKTS
                     LSRVLAGFLQPKSGEVLVDGSHLPNKAFRPVQLIQQHPEQTMNPLWPMKKSLEEAYYP
                     SQDLRDAFGIQEKWLNRRPSELSGGELQRFSIVRSLHPETKYLIADEMTTMLDSITQA
                     SVWKSLLEIVKDRNLGLIVISHDFDMLEKLCDACYMIEENRTQLFKHT"
     gene            complement(12446..12646)
                     /locus_tag="ACF4ZO_001442"
     CDS             complement(12446..12646)
                     /locus_tag="ACF4ZO_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HFD5486967.1"
                     /translation="MSEEKLKSKIEQASGGLKEGAGKLTGDKELEAKGFVEKTIAKGK
                     ELADDAKEAVEGAVDAVKEKLK"
     gene            complement(12815..15286)
                     /locus_tag="ACF4ZO_001443"
     CDS             complement(12815..15286)
                     /locus_tag="ACF4ZO_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HFD5486968.1"
                     /translation="MKKTYGYIGSVAAILLATHIGSYQLGKHHMGLATKDNQIAYIDD
                     SKGKAKAPKTNKTMDQISAEEGISAEQIVVKITDQGYVTSHGDHYHFYNGKVPYDAII
                     SEELLMTDPNYHFKQSDVINEILDGYVIKVNGNYYVYLKPGSKRKNIRTKQQIAEQVA
                     KGTKEAKEKGLVQVAHLSKEEVAAVNEAKRQGRYTTDDGYIFSPTDIIDDLGDAYLVP
                     HGNHYHYIPKKDLSPSELAAAQAYWSQKQGRGARPSDYRPTPAPGRRKAPIPDVTPNP
                     GQGHQPDNGGYHPAPPRPNDASQNKHQRDEFKGKTFKELLDQLHRLDLKYRHVEEDGL
                     IFEPTQVIKSNAFGYVVPHGDHYHIIPRSQLSPLEMELADRYLAGQTEDNDSGSEHSK
                     PSDKEVTHTFLGHRIKAYGKGLDGKPYDTSDAYVFSKESIHSVDKSGVTAKHGDHFHY
                     IGFGELEQYELDEVANWVKAKGQADELAAALDQEQGKEKPLFDTKKVSRKVTKDGKVG
                     YIMPKDGKDYFYARDQLDLTQIAFAEQELMLKDKKHYRYDIVDTGIEPRLAVDVSSLP
                     MHAGNATYDTGSSFVIPHIDHIHVVPYSWLTRDQIATIKYVMQHPEVRPDVWSKPGHE
                     ESGSVIPNVTPLDKRAGMPNWQIIHSAEEVQKALAEGRFATPDGYIFDPRDVLAKETF
                     VWKDGSFSIPRADGSSLRTINKSDLSQAEWQQAQELLAKKNAGDATDTDKPKEKQQAD
                     KSNENQQPSEASKEEEKESDDFIDSLPDYGLDRATLEDHINQLAQKANIDPKYLIFQP
                     EGVQFYNKNGELVTYDIKTLQQINP"
     gene            complement(15299..16219)
                     /gene="lmb"
                     /locus_tag="ACF4ZO_001444"
     CDS             complement(15299..16219)
                     /gene="lmb"
                     /locus_tag="ACF4ZO_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/laminin-binding adhesin Lmb"
                     /protein_id="HFD5486969.1"
                     /translation="MKKGFFLMAMAVSLVMIAGCDKSANPKQPTQGMSVVTSFYPMYA
                     MTKEVSGDLNDVRMIQSGAGIHSFEPSVNDVAAIYDADLFVYHSHTLEAWARDLDPNL
                     KKSKVDVFEASKPLTLDRVKGLEDMEVTQGIDPATLYDPHTWTDPVLAGEEAVNIAKE
                     LGRLDPKHKDSYTKKAKAFKKEAEQLTEEYTQKFKKVRSKTFVTQHTAFSYLAKRFGL
                     KQLGISGISPEQEPSPRQLKEIQDFVKEYNVKTIFAEDNVNPKIAHAIAKSTGAKVKT
                     LSPLEAAPSGNKTYLENLRANLEVLYQQLK"
     gene            complement(16471..>19517)
                     /gene="scpA/B"
                     /locus_tag="ACF4ZO_001445"
     CDS             complement(16471..>19517)
                     /gene="scpA/B"
                     /locus_tag="ACF4ZO_001445"
                     /EC_number="3.4.21.110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021340616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="C5a peptidase ScpA/B"
                     /protein_id="HFD5486970.1"
                     /translation="VNDKIAYYHDYSKDGKTAVDQEHGTHVSGILSGNAPSETKEPYR
                     LEGAMPEAQLLLMRVEIVNGLADYARNYAQAIRDAVNLGAKVINMSFGNAALAYANLP
                     DETKKAFDYAKSKGVSIVTSAGNDSSFGGKTRLPLADHPDYGVVGTPAAADSTLTVAS
                     YSPDKQLTETATVKTADQQDKEMPVLSTNRFEPNKAYDYAYANRGMKEDDFKDVKGKI
                     ALIERGDIDFKDKIANAKKAGAVGVLIYDNQDKGFPIELPNVDQMPAAFISRKDGLLL
                     KENPQKTITFNATPKVLPTASGTKLSRFSSWGLTADGNIKPDIAAPGQDILSSVANNK
                     YAKLSGTSMSAPLVAGIMGLLQKQYETQYPDMTPSERLDLAKKVLMSSATALYDEDEK
                     AYFSPRQQGAGAVDAKKASAATMYVTDKDNTSSKVHLNNVSDTFEVTVTVHNKSDKPQ
                     ELYYQATVQTDKVDGKHFALAPKALYETSWQKITIPANSSKQVTVPIDASRFSKDLLA
                     QMKNGYFLEGFVRFKQDPTKEELMSIPYIGFRGDFGNLSALEKPIYDSKDGSSYYHEA
                     NSDAKDQLDGDGLQFYALKNNFTALTTESNPWMIIKAVKEGVENIEDIESSEITETIF
                     AGTFAKQDDDSHYYIHRHANGKPYAAISPNGDGNRDYVQFQGTFLRNAKNLVAEVLDK
                     EGNVVWTSEVTEQVVKNYNNDLASTLGSTRFEKTRWDGKDKDGKVVANGTYTYRVRYT
                     PISSGAKEQHTDFDVIVDNTTPEVATSATFSTEDRRLTLASKPKTSQPVYRERIAYTY
                     MDEDLPTTEYISPNEDGTFTLPEEAETMEGGTVPLKMSDFTYVVEDMAGNITYTPVTK
                     LLEGHSNKPEQDGSDQVPDKKPETKPEQDGSGQAPDKKPETKPEQDGSGQAPDKKPEA
                     KPEQDGSGQTPDKKPETKPEKDSSGQTPGKTPQKGQPSRTLEKRSSKRALATKASARD
                     QLPTTNDKDTNRLHLLKLVMTTFFFGLVAHIFKTKRQKETKK"
BASE COUNT         5597 a         3985 c         3759 g         6176 t
ORIGIN      
        1 tgacgaaaag cggtctacct cttggcattt tggtgaatag cggagctcat aacgatagtc
       61 tcctgttaca actgggacag ctctttgaaa aagcaaatcg tttccatatc ctgacggctg
      121 gcaaaaaagg attaccagaa acacctacac atgagcataa cctctcaact caatctgaaa
      181 acaagcaagg cgttgccatt ccagtgactt atcaaaccaa gggatttact actggaccaa
      241 ccaagggcca gaacggctta gtaaccctcc ctcaaactgg tgatggtcag tcaaaaggtg
      301 tgttgttaag tagctacatc agccttttcc ttggaaccct cttcttagca ggaagcttct
      361 ggagcaataa gttaaaagac taggctattg tcgtcggaga tttaacctac ctaaacattc
      421 actgctgctt gccttacgat aagagtatat tgtagtcaat caagactgaa ctttcttagt
      481 gaaagttcag tctttttacg tggccaaaag acagttgttg cctgttctca ttaggcttag
      541 caaccgcttt tatgatataa tttgggtatg catagaaaaa cgattattga tttcaaagag
      601 ctcgggcgac gctatctttt tgatgagcca ttagtagaat tggtagccaa gtccttagat
      661 caggtcggtc cagtcattga aaaagtacaa cactaccaac agctgggcta ttacgtggtg
      721 ggctatctca gttatgaaac agctgctttt tttgacaatg ccctacaaac ccataataac
      781 agactaggca acgagtacct tgcctatttt acagtgcaca aaacctgtca aaaaaaagac
      841 ctacctcttg attatgacag cattactatc cctaaccaat gggtcagcgc aactcaaaaa
      901 gaagcctatc aaaaagccat tgaatccatt caccgtgaga tgcaacaggg caatacttat
      961 caggttaact ataccattca attaactcag gaactcaatg cagctgacag cttcgccatt
     1021 tacaataaac tcgtcgttga acaggctgct ggctacaatg cctatatcgc ccatgatgag
     1081 tttgccgtta tttcagctag tcctgagttg ttctttaaac aggaagggaa tcaactcacc
     1141 accagaccta tgaagggcac caccaagcgt ggggttaaca cctggctgga tcaacaagaa
     1201 catgactggc tccaagctga cgggaaaaat cgctctgaaa acatgatgat tgtggatttg
     1261 ctccgcaatg acatgggaaa aatttgccaa ataggcagtg tttgtgttga taggctctgt
     1321 gaggtcgagc gatactctac cgtctggcaa atgacctcaa ctattgttgg tgacctcaaa
     1381 gcggactgtg acctgataga cattctcaca gctctctttc cttgtggctc tatcacgggg
     1441 gctcctaaag tctccaccat ggcaattatc acatctctgg agccaaaacc aagggggatt
     1501 tattgtggaa gtattggcat ttgtttacct gacggtcgcc gtttcttcaa tgttcccatt
     1561 agaaccatcc agctcagtca tgatcaagct acttatggtg tcggaggcgg catcacttgg
     1621 caaagcaagt gggaagacga atacgaagaa gtccatcaaa aaacagcttt tctctatcgg
     1681 cacaaacaaa tctttgacct caaaacaacc gccaaggtgg aacaccaaaa aatagccttc
     1741 cttgagcaac acctcaatcg ccttaaagaa gcagccactt attttgctta cccttacgat
     1801 gagaaagctt tgcagaaaca actgtcaacc tatttggaaa ataagaataa tgctgcctac
     1861 cgtttgatga ttcgtttatc caaagatgga aagattagcc tctctgatca acccttggaa
     1921 cctttgtcag ccgattttct gacagctcaa ctctctttac agaagaagga cgtgacagct
     1981 tcgcctttta cctactttaa gaccagctac cggcctcata ttgagcaaaa atcttatgaa
     2041 cagctattct ataaccaagc ggggcaatta ttggaaacgt ccattggcaa tctctttgtt
     2101 cagctgggtc agaccctcta cacaccacca gtggctgtgg ggattttacc aggacttttt
     2161 cgccaagagc tgctagctac tggtcaagct caggaaaaag aggtgacact agctgattta
     2221 aaagaggcta gcgctatttt tggaggaaat gctgtccgtg gcctctatcc tctcaacctt
     2281 gagcttactc accttgatgc cctcttagct aagagtcaag cctaaactgc cactcatctt
     2341 ttgttattaa ggaacctatg atactcttaa ttgataatta cgattcattt acctacaacc
     2401 tcgcccaata tttaagtgaa tttgacgaga cgattgtctt gtataaccaa gacccaaact
     2461 tatatgacat ggccaaaaaa gctaacgctc tagtcctctc acctggtcct ggttggccca
     2521 aggaagccaa ccaaatgcca aaactcattc aagactttta ccaaacaaaa cctatcttag
     2581 gagtgtgtct gggacaccaa gcgatcgctg aaacattagg gggaacctta cgcttggcca
     2641 aacgcgtcat gcatgggaga caaagcacca ttgaaacgca aggccctgct agtctttttc
     2701 gctccctgcc acaagagatc accgtcatgc gctaccattc catcgttgtg gatcagttac
     2761 caaaaggttt tagcgtaact gctagagact gtgacgatca agaaatcatg gcctttgaac
     2821 accacaccct gccacttttt gggctacaat ttcacccaga aagcatcgga actcctgatg
     2881 gcatgaccat gattgccaac ttcatcgcag ctattccccg ttaatcccat tccccaaaag
     2941 aaaggaggac agttacatgc ctgatcattt agcgctcaga atgcgcccca aaaccatttc
     3001 agaggtcatc ggacaaaaac accttgttgg cgaaggcaaa atcatccgtc gcatggtgga
     3061 agcaaataga ctatcgtcca tgatcctcta tggccctcca ggaatcggta aaacttccat
     3121 tgcttctgct attgctggta ctactagata tgcctttcgg acctttaatg ccaccattga
     3181 cagcaaaaaa cgtctccaag aaattacgga agaagctaaa ttttctggtg gcttggtatt
     3241 attactagac gagattcatc gccttgataa gacaaaacaa gattttcttt tacctttact
     3301 tgagaatggc accattatca tgattggcgc aaccactgag aaccccttct tttcagtgac
     3361 acccgctatc agaagcaggg tccagatttt tgaattggaa ccactttcta acgaggatat
     3421 taaaacagcc attcagctag caatttccga caaagaacgg ggatttcctt ttttagtgac
     3481 aattgatgat gaggcgctag atttcattgt taccgccaca aatggagacc tacgatctgc
     3541 ttataattcc ttggatctag cagtcatgtc tacaaagcca gatagcgatg ggaagcgaca
     3601 catcacctta gacactgttg aaaattcctt gcagcgcagc tatattacca tggataaaga
     3661 tggcgacggg cattatgatg ttttatctgc cttacaaaaa tccattagag gttctgatgt
     3721 caatgctagc ctgcactacg ccgctcgttt agtagaagct ggagacttgc ctagtttagc
     3781 aagacgattg accattattg cttacgaaga tattggctta gccaaccctg acgcccaagt
     3841 tcataccgtc accgcactag atgccgctca acgcattggt tttccagaag ctcgtattct
     3901 tatcgctaac gtggtcattg atttggctct atctcctaaa tcaaattcag cttatttagc
     3961 tatggatgca gctttagctg atttgagaac atcaggtaac ctccccattc caaggcatct
     4021 tagagacggg cattatgctg gcagtaagga cctaggcaat gccaaagatt acctctaccc
     4081 acacgcctac cctgaaaaat gggtcaaaca acaataccta ccagataaat tagtaggaca
     4141 tcattatttt gaagccaatg aaaccggtaa atacgaacgc gcacttggtt caaataaaga
     4201 gcgtattgat aagctctcag actgactgct agttttaaaa atcgcaaccg atttcaaaaa
     4261 tcgataattt tgcttgaaaa aattttaaaa agtggtatta taaaagtaca gaaacattgc
     4321 tgtggcatac gaatccacat ctaagtgttg accgactatt tctttgtatt ttcgggaaac
     4381 aaagactctt tctagtctgc aagccgtttc acgcggacgc aacttccaag aaagagcgcg
     4441 ttacccacct gcttatactg cgcgggctca atacaaaaac gtggatcacc ggtgccaata
     4501 cagcattctt gcctccttag ctcagttggt agagcagtag actcttaatc tatgggtcac
     4561 aggttcgagc cctgtagggg gtatacaact atacatgaaa aaacctttgt ttaaaggctt
     4621 tttttgcttg tcagaagagg atttgttcca tcatttatcc ccgcagtaat ttttttatgg
     4681 tatgatacca attaaagcgc ttaagattaa ggtggagact gttatgaaaa taattgagta
     4741 caaaggaaat tacagagatg acctcatttt tatggtcttg gaagcaaaaa atgccttaag
     4801 gagaattccc agcattaacc cggatctttt gacaattgaa acaagttatt tggaaaaagg
     4861 ggattgtttt tggctagcgg tcaatgaaga aagtcgtgtt attggctcaa tcgcttattc
     4921 ttctattccc aaaacaaatg aggtcttctt gcaccgtctc ttcatcaaac caagcttaaa
     4981 acatcaaggc attggcagtc aacttctgac gtttgcagaa gattatctaa ggaaaatcgg
     5041 caagagtcat gttcgtatcc acttaggtca acctaaagaa caatggtttg agtcttatcg
     5101 gttttatcct aaacatggtt atcaatttta tgatgacacg catctcatca agaaactaat
     5161 ctaaacacat ttcacaccct ttatagtcat ttcatacgtc atttttagga ggtatccatt
     5221 gaaaattgcc atcattggac atagtggctc tggaaagtca accttagcac gatttttagg
     5281 ccaacattac cattgtgagg tattccattt agaccaacta cacttctcat cgaactggca
     5341 agaacggtca gatcatgaca tgatagctga tttatcaaca tgcctgctca aacaagattg
     5401 gattattgag gggaattatg ccaattgtct ctatgaagag cgcatgagtg aagctgatta
     5461 cattatctat gttaatttca gtcggtttca ttgtgtctat cgagcattta agcgttattt
     5521 aaactatagg agaaaaacgc gtcctgatat ggctgacaac tgtcaggaaa aatttgacgt
     5581 tgcgtttgtg aaatggattc tactaggtgg acgttcaaga aaccagttaa aaaaatacca
     5641 atctgttatc caaaaatacc ctcataaaac cattgtcttg acaaatcaaa agcagctaag
     5701 tcattatatg aatacgatca actaattaga gtgcaaaact aaaataacca cgggtaatcc
     5761 gggctattca gactgaaagc ctttgtttaa aggctttttt gcttgtttca taactaatcg
     5821 gcttaattaa aagcgtcaat ccacttttag tatcatgtct caattttcat tcgatagtca
     5881 gcaagtatat ctacaaaatt gttaatgatt atttcttttg aaagtgttat attaaaacat
     5941 aataaaataa taactcctga aaagaggcta tttatgaaaa aaacaaaact tattttttct
     6001 ttgacttcaa tattcattgc aataatttct cgtcctgtgt ttggattaga agtagataat
     6061 aattcccttc taaggaatat ctatagtacg attgtatatg aatattcaga tacagtaatt
     6121 gattttaaaa ccagtcataa cttagtgact aagaaacttg atgttagaga tgctagagat
     6181 ttttttatta actccgaaat ggacgaatat gcagccaatg attttaaagc tggagataga
     6241 atagctgtgt tctccgtccc atttgattgg aactatttat caaaaggaaa agtcacagca
     6301 tatacgtacg gcggaataac accctaccaa aaaacttcaa tacctaaaaa tatccctgtt
     6361 aatttatgga ttaatagaaa gcagattcct gtcccctata atcaaatatc aactaacaaa
     6421 acaacagtta cagctcaaga aattgatcta aaggttagaa aatttttaat agcacaacat
     6481 caattatatt cttctggttc taactacaaa agtggtaaat tagtttttca tacaaatgat
     6541 aattcagata aatattctct cgatcttttc tatacaggat atagagataa agaaagtatt
     6601 tttaaagtat acaaagacaa taaatctttc aatatagata aaattgggca tttagatata
     6661 gaaattgact cctaattcaa tttttcaata taacttttat acaataagct attccaaata
     6721 gattgaatcc tctaaaaagt aagtatgtct ttttttatat cacttaggtt ttgttctaaa
     6781 tttgttctag aatgctatac tttctatatt aattttaaaa aacaaaaatt gataaattcc
     6841 ttgataatac tagccatttt tgtttataaa ttttctttat tatgcttttt ctacttgtag
     6901 ggggtatgat acaaaaatga caaaagcttt tagaacgtag acagacccag tgtgatgctc
     6961 aaaaagcatg aactgctctg ctaatgtgat acccgatttc ctatttctgc gaacgaagta
     7021 agccaagacc aaatcagatg ttttttgctg tggagaaagt cgctgccgcc cgaaccacct
     7081 caaaaaaagt atcaaaaaag acttttttca ctgttatttt tacctgtatt aatggctatc
     7141 cgaagttttt gattcccttc gtaaactaca attcctttat ttcttagtga tcagtttaat
     7201 tcttttttaa tctaaaataa gtcatgaaac ctctttatct tttgttaata catcaactta
     7261 taaaaaaaac ctgagtatct tcctgaaaat aacaaaaatt ctaattaacc agttaaacaa
     7321 ttgccctcct atttgtttat tgctataatg agatggagtc gttactatta ttatttatta
     7381 attagaaata aggagatttg attgtgtcaa aatacctaaa atacttctct attatcacgt
     7441 tatttttgac tgggcttatt ttagttgctt gtcaacaaca aaagcctcaa acaaaagaac
     7501 gtcagcgcaa acaacgtcca aaagacgaac ttgtcgtttc tatgggggca aagctccctc
     7561 atgaattcga tccaaaggac cgttatggag tccacaatga agggaatatc actcatagca
     7621 ctctattgaa acgttctcct gaactagata taaaaggaga gcttgctaaa acataccatc
     7681 tctctgaaga tgggctgact tggtcgtttg atttgcatga tgattttaaa ttctcaaatg
     7741 gtgagcctgt tactgctgat gatgttaagt ttacttatga tatgttgaaa gcagatggaa
     7801 aagcttggga tctaaccttc atcaagaacg ttgaagtagt tgggaaaaat caggtcaata
     7861 tccatttgac tgaggcgcat tcgacattta cagcacagtt gactgaaatc ccaatcgtcc
     7921 ctaaaaaaca ttacaatgat aagtataaga gcaatcctat cggttcagga ccttacatgg
     7981 taaaagaata taaggctgga gaacaagcta tttttgttcg taacccttat tggcatggga
     8041 aaaaaccata ctttaaaaag tggacttggg tcttacttga tgaaaacaca gcactagctg
     8101 ctttagaatc tggtgatgtt gatatgatct acgcgacacc agaacttgct agtaagaaag
     8161 tcaaaggcac tcgcctcctt gacattccat caaatgatgt gcgcggctta tcattacctt
     8221 atgtgaaaaa aggcgtcatc actgattctc ctgatggtta tcctgtagga aatgatgtca
     8281 ctagtgatcc agcaatccgc aaagccttga ctattggttt aaatagacaa aaagttctcg
     8341 atacggtttt aaatggttat ggtaaaccag cttattcaat tattgataaa acaccatttt
     8401 ggaatccaaa aacagccatt aaagataata aagtagctaa agctaagcaa ttgttgacaa
     8461 aagcgggatg gaaagaacaa gcagacggta gccgtaaaaa aggtgacctt gatgcagcgt
     8521 ttgatctgta ctaccctact aatgatcaat tgcgagcgaa cttagccgtt gaagtagcag
     8581 agcaagccaa agccctaggg attactatta aactcaaagc tagtaactgg gatgaaatgg
     8641 caacgaagtc acatgactca gccttacttt atgccggagg acgtcatcac gcgcagcaat
     8701 tttatgaatc acatcatcca agcctagcag gtaaaggttg gaccaatatt acgttttata
     8761 acaatcctac cgtgactaag taccttgaca aagcaatgac atcttctgac cttgacaaag
     8821 ctaacgaata ttggaagtta gcgcagtggg atggcaaaac aggtgcttct actcttggag
     8881 atttgccaaa tgtatggttg gtgagcctta accatactta tattggtgat aaacgtatca
     8941 atgtaggtaa acaaggcatc cacagtcatg gtcatgattg gtcattattg actaacattg
     9001 ccgagtggac ttgggatgaa tcaactaagt aacgcgttta gttaatacag cgactttaag
     9061 tttggagtct gagaaaacaa gatacacaaa actgtgctga tcgtttcctc ggctcctttt
     9121 cttatcgatt aaggagattt cattgtgaaa cgtactacca ttattatcat ctggaaaatc
     9181 atcagatgta tcacacttat ttttggggta tctgttttga ccttcgtttt gttaaaacaa
     9241 tctccagtag atccagtcat ggcaagtgtc aattatgaca catcactaac ccctgctcag
     9301 tacaaagcga ttgctcacca ctatggcttg gataagccag ctctagtcca atattttatt
     9361 tggttgaaaa atgtgataca gggacattta gggacctcac tcgtttatcg gcaacctgtt
     9421 agtgatatta ttagatcacg ggcaggtgct tctttcatac ttatgggact ctcttggatc
     9481 ttatcgggtc ttattggatt tatcttagga acgttatccg ctttccatca agggaaatta
     9541 cttgaccgag ttgtcaggtg gttttcttac cttcagatat cagtaccaac gttttggatt
     9601 ggcctcattt ttttattaat cttttctgtc cagctggggt ggttcccgat tggtatttct
     9661 tccccgattg ggactttaag tcaagatatt acgttagctg atcggattaa gcaccttatg
     9721 ttacctgttt tcacgctaag tattctaggc attgccaatg tcactcttca tacgagaact
     9781 aaaatgatgt cggtgctttc tagtgaatat gtcttatttg ccagagcgcg tggggaaaca
     9841 cagtggcaaa tttttaaaaa tcattgtctt agaaatgcta tcgtaccagc tattacactg
     9901 catttttcct attttggaga attgtttgga ggatctgttc ttgctgagca agttttctca
     9961 tatcctggct tagggtctac cctcactgaa gcaggactta aaagtgatac accgctactt
    10021 ctagctatcg tgatgatagg gacattattt gtttttgcgg gcaatcttat tgcggacatt
    10081 ttaaatagca tcatcaatcc acagttaagg agaaaagtat gatattgaaa cgtcgaacga
    10141 tggttttatg gcaactaggt atcgccattt ctctcattct tagtattcta gccttaaacc
    10201 tttatttcta taggacgcct ttggaaacca atgcagcttt acgcaacctc gccccttcct
    10261 taaaccatct ttttgggaca gatggtttag gtagggatat gtttgtcaga acgattaaag
    10321 ggctttattt ctctttacaa gtcggcttat taggtgccct tatgggagtc tttcttgcga
    10381 ccgtttttgg agtgcttgca ggtctaggaa atagccttat tgataaaata atagcatggt
    10441 tggttgattt gtttattggt atgcctcatt tgatttttat gattctcatt tcttttgttg
    10501 ttggtaaagg ggctcaaggg gttatcattg caacggctgt tacccattgg ccctctctag
    10561 caaggcttat ccgcaatgaa gtctatgatc taaagaataa agcctttgtc cagctctcta
    10621 aaagcatggg aaaaacgcct tattatattg tgaggcatca tatcctgcct ttgattgctt
    10681 ctcaaatttt cattgggttt atcctcttat ttccgcacgt catcttgcat gaagcatcca
    10741 tgactttctt aggatttggc ctttctgccg aacaaccttc ggttggtatc attttgtcag
    10801 aggcagctaa gcatatctct cttggcaatt ggtggttggt gatttttcca ggcctttatc
    10861 ttattttggt tgtcaatgcc tttgatacta tcggagaatc tttaaagaaa ctcttttacc
    10921 ctcaaacgga tcatttttag gaggtagaga tatgacagaa acattattaa gcattaaaga
    10981 cctctccatc accttcactc aatacggaag atttttaaaa ccatttcaat ccacaccgat
    11041 acaagcgctg aatttagaag ttaaaaaagg tgagttatta gctattatag gtgctagtgg
    11101 ttcaggcaag agtttattag cacatgctat tatggatatt cttcctaaaa atgcagctgt
    11161 aacaggagat atgatttatc gtggtcaatc actaacttct aaacgcatca aacagttgcg
    11221 aggaaaagaa atgacgttga ttccacaatc cgttaattat ttagatccat ctatgaaagt
    11281 caagcatcag gtgcgcttgg gtatctcaga aaatgctaag gctactcaag aaggattgtt
    11341 tcaacagttt ggattaaaag aaagtgatgg tgacttgtat cctttccaac tttctggcgg
    11401 aatgctccga cgtgttttgt ttacaacgtg tattagtgat acggtttctt tgattattgc
    11461 ggatgagccc acccctggat tacatccaga tgctctgcaa atggttttag atcaactacg
    11521 ctcctttgca gataaaggaa taagcgttat ctttatcact catgatattg tagcagctag
    11581 tcaaattgcg gatcgtatta ctatttttaa agagggaaaa gctattgaaa cagccccagc
    11641 tagctttttt agcggaggtg gggagcaatt acaaacagaa tttgcgagac gtttatggcg
    11701 cacactccct caacaagact ttttgaaagg agttactcat gaccttagag gctaaaaagc
    11761 ttggctttta tcataaaaaa gatcaatggc tttttaagga gattgattta gaggtagcac
    11821 ctggtcaaat cttagggata tttggaccaa gtgggtgtgg aaaaacgagt ttatccagag
    11881 tgcttgccgg ttttttgcag cctaaatctg gtgaagtatt agttgatggc agtcatttgc
    11941 ctaacaaagc atttagacct gtacaactta tccaacaaca tcctgaacaa accatgaatc
    12001 ctttatggcc tatgaaaaaa agtttggaag aagcctacta tccaagtcaa gatttgcgag
    12061 atgcttttgg cattcaagaa aaatggctaa atcgtcgccc tagtgaactc tcgggagggg
    12121 aattgcaacg cttttcgatt gtgcgttcat tacatccaga gacgaaatac cttattgcgg
    12181 atgaaatgac tactatgttg gatagcatta cacaagctag tgtatggaaa agcctgttag
    12241 agattgtaaa ggatagaaat ttaggtctca tcgttattag tcatgatttt gatatgttag
    12301 aaaaactttg tgacgcgtgc tatatgattg aagagaatcg tactcaactg ttcaagcata
    12361 cctaacacct acggttatta cctattgagt cttttcctaa caaaatcaca ccattaaaaa
    12421 aaccagctgt aagctggttt tttaattatt ttaatttttc cttaacggca tctacagcac
    12481 cttcaaccgc ttcttttgca tcgtctgcaa gttctttgcc tttagcaatt gttttttcaa
    12541 caaatccttt tgcttctagc tctttatcac ctgtcaactt accagcacct tcttttaggc
    12601 caccagatgc ttgctcaatt tttgatttta atttttcttc tgacatgatt agaatcctcc
    12661 tctttttttt attattctaa catggatacc atctctttgc aaaagaaaac cgctattatc
    12721 caacttttat cactactcgt tacataaaat gacttcaaaa tcaccgtaac ttgctttgac
    12781 aaagcagtgc tttaacaatg agatcttctt ttggttaagg gtttatttgt tgaagtgtct
    12841 tgatatcata agttaccaat tcaccatttt tattataaaa ttggacacct tctggttgga
    12901 aaatgagata cttaggatcg atattagctt tttgtgctaa ttgattgata tgatcttcta
    12961 gggttgctct atctagacca tagtctggta aactatctat aaagtcatct gattcttttt
    13021 cttcttcttt actggcttca cttggctgtt ggttttcatt gctcttatct gcctgttgct
    13081 tttctttggg tttatccgta tcagtagcat caccagcgtt tttctttgcc aataactctt
    13141 gagcttgttg ccactcagct tgggatagat cagatttatt aatggttctc aatgaactgc
    13201 catctgctct tgggatgcta aaggagccat ctttccatac aaaagtttct ttggccaaaa
    13261 catctcgtgg atcgaaaata tagccgtctg gtgttgcaaa acgaccttct gctagggctt
    13321 tttgaacttc ttcagcagaa tggataattt gccagtttgg cataccagca cgtttatcaa
    13381 gaggcgtaac atttggaatg accgaacctg actcttcatg ccctggctta gaccatacat
    13441 ccggacgaac ttcggggtgt tgcatcacat acttgattgt tgcaatctga tcgcgcgtca
    13501 accatgaata cggaacgaca tggatatgat caatatgagg gataacaaac gaacttccag
    13561 tatcgtaagt agcattacca gcatgcatcg gcagacttga cacatctaca gcaagtcgtg
    13621 gctcaatacc tgtgtcaaca atgtcataac ggtaatgctt cttatctttg agcattagtt
    13681 cttgttcggc aaaggcaatc tgagtcaaat caagttgatc acgagcatag aaatagtcct
    13741 tgccatcttt tggcataata tagcccactt taccatcttt tgttactttg cgactcactt
    13801 ttttagtgtc aaagagtggc ttttctttgc cttgttcctg atccaaagca gcagcaagct
    13861 catcagcttg accttttgct ttcacccagt tagcgacctc atccaactca tattgttcaa
    13921 gttctccaaa tcctatataa tggaaatgat ctccgtgttt agctgtaact cctgatttat
    13981 ccactgaatg aatggattct ttactaaaaa cataagcatc actcgtatca tatggtttac
    14041 catctaagcc ttttccgtaa gctttgatgc gatgaccaag aaaggtatgt gtcacttctt
    14101 tatctgatgg ttttgagtgc tctgaacctg agtcattgtc ctcagtttgg ccagctaagt
    14161 atcgatctgc taattccatt tcaagaggtg ataactgact tcttgggata atatgataat
    14221 gatctccatg aggcaccaca tacccaaaag cgtttgattt gatcacttga gtcggttcaa
    14281 aaatcaaccc atcttcttcc acatgacgat atttcaaatc aaggcggtgt agttgatcta
    14341 aaagttcctt aaaggttttt cctttaaact catctctttg atgtttgttt tgtgacgcat
    14401 catttggcct aggaggcgct ggatgatagc caccgttatc tggctgatga ccttgtccag
    14461 ggttaggcgt cacatcagga attggggctt tcctacgacc tggggctggt gtcgggcggt
    14521 aatcagacgg tctagcacct cgtccttgtt tttgactcca gtaggcttgt gcagcagcta
    14581 gctcacttgg agacaaatct tttttaggaa tataatgata gtgattacca tgaggtacta
    14641 aataagcatc tcctaaatca tcaatgatat ctgtcggact aaaaatatag ccatcgtctg
    14701 tagtatagcg tccttgtctt tttgcttcat tgactgccgc aacttcttct ttactgagat
    14761 gggccacttg aactaaacct ttttctttag cttctttagt tcctttggct acttgctcag
    14821 caatttgttg tttggttcga atgtttttgc gcttactacc tggcttgagg taaacataat
    14881 agttgccatt gactttaata acgtaaccgt ctaagatttc attgataacg tctgattgtt
    14941 taaaatggta attaggatcc gtcatcaaca actcttcact aataatcgca tcataaggaa
    15001 ctttcccatt gtaaaaatga taatggtcac cgtgtgaggt cacataacct tggtcagtaa
    15061 ttttgactac gatctgttca gcagagatgc cttcttcagc actgatttga tccatcgttt
    15121 tgtttgtttt aggggctttt gccttacctt tgctatcatc aatataggca atctgattgt
    15181 cctttgttgc tagacccata tgatgcttac caagttggta acttccaata tgagtagcta
    15241 gtaaaatggc agcaactgaa ccgatataac catatgtttt cttcactaat aatctccttt
    15301 acttcaactg ttgatagagc acttccaaat ttgctctaag attttctaga tatgtcttgt
    15361 ttccgcttgg agcagcttca agtggactta atgtctttac tttagctcct gttgatttcg
    15421 caatagcatg agcaattttg ggattgacat tgtcttctgc aaaaatagtc ttgacgttgt
    15481 attctttgac aaagtcttga atttctttca attggcgagg agagggctct tgctctggag
    15541 aaatacccga gataccaagt tgtttcaagc cgaatcgttt agccagataa gaaaatgccg
    15601 tgtgctgcgt cacaaatgtt tttgagcgca cctttttaaa tttttgagtg tattcttcag
    15661 ttagttgctc tgcttctttt ttgaaagcct tagccttttt agtgtaactg tctttgtgtt
    15721 taggatccaa acgtcctagc tctttagcga tattaacagc ttcctcacca gctaaaacgg
    15781 gatccgtcca ggtatgtggg tcataaagtg tcgcagggtc aatgccttgt gtgacttcca
    15841 tatcttctag ccctttgact ctatctagtg tcaaaggttt tgacgcttca aacacatcaa
    15901 cctttgattt ttttaaatta gggtctagat cccttgccca agcttctaag gtatgtgaat
    15961 ggtaaacaaa caaatccgcg tcataaatag ctgccacatc atttacagac ggttcaaagg
    16021 aatgaatgcc tgcacctgat tggatcatcc tcacatcatt gaggtctcca gatacttctt
    16081 ttgtcatcgc atacattggg taaaagctgg ttacaactga catgccttgc gtaggctgtt
    16141 tggggtttgc tgacttatca caccctgcta tcattactaa actcacagcc atagccatga
    16201 gaaaaaaacc ttttttcata gtacctcctc aattataatt taaccagtta ttaaccagtt
    16261 aattttactc ctttatcaat gctttgtcaa tggcaaatac catcttttat cactgtatga
    16321 taaaatcaca gcaactgaag ggataagcaa aaggtaattg ttgacagcta tttgtcctaa
    16381 cttctttttg atgaggcagc acatataaaa aaatagagag aaccaaattg gttctctcta
    16441 ttaaataagc tcttatcagt ttaagtaata ctatttttta gtttcttttt ggcgttttgt
    16501 tttaaagata tgagctacta atccaaagaa gaaagtggtc ataactaact taaggagatg
    16561 taaacgattt gtatccttgt cattagtcgt tggtaactga tctcttgctg atgcttttgt
    16621 agctaaagca cgcttagaag atcgtttctc tagagtacga gaaggttgac ctttttgagg
    16681 agttttacct ggtgtttgac ctgaactatc tttttctggt ttagtttctg gttttttgtc
    16741 tggtgtttga cctgaaccgt cttgttctgg tttagcttct ggttttttgt ctggtgcttg
    16801 acctgaaccg tcttgttctg gtttagtttc tggttttttg tctggtgctt gacctgaacc
    16861 gtcttgttct ggtttagttt ctggtttttt gtctggtact tgatctgaac catcttgttc
    16921 tggcttatta gagtggccct ccaatagctt agtcactggt gtataagtga tgttaccagc
    16981 catatcttca acaacataag taaagtctga cattttcaat ggaacagtac cgccttccat
    17041 tgtttcagcc tcttcaggaa gagtaaaggt accatcttca tttggagaaa tatactctgt
    17101 tgttggcaga tcctcatcca tataagtgta agcaatacgc tcacggtaaa ccggttggct
    17161 ggtttttggt ttagatgcaa gtgtcaaacg acgatcttct gttgagaatg ttgccgatgt
    17221 tgcgacttca ggtgtcgtat tgtctacaat cacatcaaaa tcagtgtgtt gttcttttgc
    17281 acctgagcta atcggagtgt agcggacacg ataggtgtag gttccgttag caacaacttt
    17341 accgtcttta tctttaccgt cccaacgcgt tttttcaaaa cgggttgaac caagtgtgct
    17401 tgccaagtca ttgttgtagt ttttaacaac ttgctcggtt acctcacttg tccacacaac
    17461 atttccttct ttgtccaaga cttcagccac aaggttttta gcattacgca agaaagtacc
    17521 ttggaattgg acataatctc tgttaccgtc cccatttgga gagatcgcag catatggctt
    17581 gccattagcg tgacggtgga tatagtagtg gctatcatcg tcttgttttg caaaagtacc
    17641 tgcaaaaatg gtttctgtga tctctgaaga ttcgatatcc tctatgtttt caaccccttc
    17701 tttgacagct ttaataatca tccatgggtt agactctgtg gtaagtgctg taaagttatt
    17761 tttcagagcg taaaactgta atccatcacc atctaattgg tctttggcat cactatttgc
    17821 ttcatgatag tagctgctac cgtctttgct atcatagatt ggtttttcta aggctgacag
    17881 attgccaaaa tcacctcgga aaccaatata tggaatgctc ataagctctt cttttgtagg
    17941 atcttgtttg aaacgaacaa aaccttctaa gaaatagcca tttttcattt gggcaagcaa
    18001 gtccttgcta aatcgactag catcgattgg aacggtgact tgtttgctgc tattggctgg
    18061 aattgtgatt ttttgccatg atgtctcata caatgcttta ggagccaagg caaagtgttt
    18121 tccatctact ttatctgttt gaacagttgc ttggtaatac aactcttgag gtttatcaga
    18181 tttgttgtga actgttactg ttacttcaaa tgtatcagaa acattgttca ggtgaacctt
    18241 gcttgaggta ttgtccttat ctgtcacata catcgttgct gctgaagctt ttttagcatc
    18301 gactgctcct gctccttgtt ggcgaggaga aaaataagct ttttcatctt catcatataa
    18361 ggcagttgct gagctcatca atactttttt agctaaatca agacgctctg atggtgtcat
    18421 atcaggatac tgtgtctcat attgcttttg caacagtccc atgatacccg ctaccaatgg
    18481 cgcagacata ctagttccag aaagtttggc atacttgttg ttagccactg atgacaaaat
    18541 atcttggccg ggtgctgcaa tatctggctt aatattgccg tcagctgtca gaccccagct
    18601 tgagaagcgg cttagtttgg tgccacttgc tgttggcaat accttaggtg tcgcattgaa
    18661 ggtgatggtt ttttggggat tctcttttaa taagagacca tcttttcgac tgataaaggc
    18721 cgcaggcatc tgatcaacat ttggcaattc aatcgggaag cccttgtcct gattgtcata
    18781 gatcaagacc cctacagcac ccgctttttt agcgtttgca atcttatctt tgaaatcaat
    18841 atcgccacgt tcaataaggg caattttgcc tttgacatcc ttaaaatcat cctctttcat
    18901 cccacgatta gcataagcat agtcgtaagc cttgtttggc tcaaaacggt ttgttgaaag
    18961 aacaggcatt tctttatctt gctgatcggc tgttttgacc gtagcagttt cagtgagctg
    19021 tttatctggg ctgtaagaag caactgtcaa tgttgagtct gccgctgcag gtgtcccaac
    19081 caccccataa tcaggatgat ctgctagagg tagacgggtc ttgcccccaa aactactatc
    19141 attaccagct gaggtcacaa tgctaacacc ttttgatttg gcatagtcaa aggctttttt
    19201 ggtttcgtct gggaggttag cgtaggctag tgcagcatta ccaaagctca tattaatcac
    19261 cttagctccc aagttgacag catctctgat agcttgagca tagttacgag cataatctgc
    19321 tagtccattt acaatttcga cacgcatcaa aagcaattga gcctcaggca tcgcaccttc
    19381 taggcggtaa ggttctttcg tttcagatgg agcatttcct gacaagatcc ctgacacgtg
    19441 tgtgccgtgc tcttggtcga cagcggtttt accatcttta ctatagtcat ggtaataagc
    19501 aatcttatca ttgaccc
//
LOCUS       DAXMQE010000034        18703 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.034, whole genome shotgun sequence.
ACCESSION   DAXMQE010000034 DAXMQE010000000
VERSION     DAXMQE010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18703)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18703)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18703
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.034"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            complement(1..545)
                     /locus_tag="ACF4ZO_001446"
                     /pseudo
     CDS             complement(1..545)
                     /locus_tag="ACF4ZO_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612498.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            710..783
                     /locus_tag="ACF4ZO_001447"
     tRNA            710..783
                     /locus_tag="ACF4ZO_001447"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:744..746,aa:Arg,seq:tct)
     gene            complement(940..1419)
                     /gene="rlmH"
                     /locus_tag="ACF4ZO_001448"
     CDS             complement(940..1419)
                     /gene="rlmH"
                     /locus_tag="ACF4ZO_001448"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HFD5486971.1"
                     /translation="MKVKLICVGKLKERYLKDGISEYQKRLSRFCQFEMIELTDERTP
                     DKASFADNQLIMSKEAQRIHKKIGERDFVIALAIEGKQFPSETFSELISGVTVKGYST
                     ITFIIGGSLGLDSIIKKRANMLMSFGLLTLPHQLMRLVLTEQIYRAFMITQGSPYHK"
     gene            1631..2854
                     /locus_tag="ACF4ZO_001449"
     CDS             1631..2854
                     /locus_tag="ACF4ZO_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HFD5486972.1"
                     /translation="MPSMKHILKSLSILLVGFLGGLIAIITFNNLYPHSPSKINSGKA
                     TTSNMVFNNTTNTTKAVKAVQNAVVSVINYQDNPSSSLSNPYTKLFGEGRSKENKDAE
                     LSIFSEGSGVIYRKDGNSAYVVTNNHVIDGAKRIEILMADGSKVVGELVGADTYSDLA
                     VVKISSDKIKTVAEFADSTKLNVGEVAIAIGSPLGTQYANSVTQGIVSSLSRTVTLKN
                     ENGETVSTNAIQTDAAINPGNSGGPLINIEGQVIGINSSKISSTPTGSNGNSGAVEGI
                     GFAIPSTDVIKIIKQLETNGEVIRPALGISMVNLNDLSTNALSQINIPTSVTGGIVVA
                     EVKEGMPASGKLAQYDVITEIDGKTVNSISDLQSSLYGHDINDTIKVTFYRGTTKKKA
                     DIKLTKTTQDLTKTQ"
     gene            2943..3719
                     /locus_tag="ACF4ZO_001450"
     CDS             2943..3719
                     /locus_tag="ACF4ZO_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HFD5486973.1"
                     /translation="MTKELLIDLPIEDIVTNPYQPRIQFNQRELQDLATSIKSNGLIQ
                     PIIVRKSDIFGYELVAGERRLKASKMAGLKKIPAIIKKISTLESMQQAIVENLQRSNL
                     NAIEEAKAYQLLVEKKHMTHDEIAKYMGKSRPYISNTLRLLQLPAPIIKAIEEGKISA
                     GHARALLTLSDDKQQLYLTHKIQNEGLSVRQIEQLVTSTPSSKLSKKTKNIFATSLEK
                     QLAKSLGLSVNMKLTANHSGYLQISFSNDDELNRIINKLK"
     gene            3922..5277
                     /gene="dnaA"
                     /locus_tag="ACF4ZO_001451"
     CDS             3922..5277
                     /gene="dnaA"
                     /locus_tag="ACF4ZO_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003688 - DNA replication origin binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA];
                     GO_process: GO:0006275 - regulation of DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HFD5486974.1"
                     /translation="MTENEQIFWNRVLELAQSQLKQATYEFFVHDARLLKVDKHIATI
                     YLDQMKELFWEKNLKDVILTAGFEVYNAQISVDYVFEEDLMIEQNQTKINQKPKQQAL
                     NSLPTVTSDLNSKYSFENFIQGDENRWAVAASIAVANTPGTTYNPLFIWGGPGLGKTH
                     LLNAIGNSVLLENPNARIKYITAENFINEFVIHIRLDTMDELKEKFRNLDLLLIDDIQ
                     SLAKKTLSGTQEEFFNTFNALHNNNKQIVLTSDRTPDHLNDLEDRLVTRFKWGLTVNI
                     TPPDFETRVAILTNKIQEYNFIFPQDTIEYLAGQFDSNVRDLEGALKDISLVANFKQI
                     DTITVDIAAEAIRARKQDGPKMTVIPIEEIQAQVGKFYGVTVKEIKATKRTQNIVLAR
                     QVAMFLAREMTDNSLPKIGKEFGGRDHSTVLHAYNKIKNMISQDESLRIEIETIKNKI
                     K"
     gene            5432..6568
                     /gene="dnaN"
                     /locus_tag="ACF4ZO_001452"
     CDS             5432..6568
                     /gene="dnaN"
                     /locus_tag="ACF4ZO_001452"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HFD5486975.1"
                     /translation="MIQFSINRTLFIHALNATKRAISTKNAIPILSSIKIKVTPTGVT
                     LTGSNGQISIENTIPVSNENAGLLITSPGAILLEASFFINIISSLPDISINVKEIEQH
                     QVVLTSGKSEITLKGKDVDQYPRLQEVSTENPLILKTKLLKSIIAETAFAASLQESRP
                     ILTGVHIVLSNHKDFKAVATDSHRMSQRLITLDNTSADFDVVIPSKSLREFSAVFTDD
                     IETVEVFFSPSQILFRSEHISFYTRLLEGNYPDTDRLLMTEFETEVVFNTQSLRHAME
                     RAFLISNATQNGTVKLEITQNHISAHVNSPEVGKVNEDLDIVSQSGSDLTISFNPTYL
                     IESLKAIKSETVKIHFLSPVRPFTLTPGDEEESFIQLITPVRTN"
     gene            6643..6840
                     /locus_tag="ACF4ZO_001453"
     CDS             6643..6840
                     /locus_tag="ACF4ZO_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HFD5486976.1"
                     /translation="MYQIGSFVEMKKPHACVIKETGKKANQWKVLRVGADIKIQCTNC
                     QHVIMMSRYDFDRKLKKVLQP"
     gene            7170..8285
                     /gene="ychF"
                     /locus_tag="ACF4ZO_001454"
     CDS             7170..8285
                     /gene="ychF"
                     /locus_tag="ACF4ZO_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HFD5486977.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTELITPKKTVPTTFEFTDIAGIVKGASRGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPIADIDTINLELILADLESINKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTEEEAKVVKGLFLLTTKPVLYVANVDEDKV
                     ANPDGIDYVKQIRDFAATENAEVVVISARAEEEISELDDEDKEEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGIKAPQAAGIIHSDFERGFIRAVTMSYDD
                     LMIYGSEKAVKEAGRLREEGKEYVVQDGDIMEFRFNV"
     gene            8355..8924
                     /gene="pth"
                     /locus_tag="ACF4ZO_001455"
     CDS             8355..8924
                     /gene="pth"
                     /locus_tag="ACF4ZO_001455"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HFD5486978.1"
                     /translation="MVKMIVGLGNPGSKYEKTKHNIGFMAIDNIVKNLDVTFTDDKNF
                     KAQIGSTFINHEKVYFVKPTTFMNNSGIAVKALLTYYNIDITDLIVIYDDLDMEVSKL
                     RLRSKGSAGGHNGIKSIIAHIGTQEFNRIKVGIGRPLKGMTVISHVMGQFNTEDNIAI
                     SLTLDRVVNAVKFYLQENDFEKTMQKFNG"
     gene            8927..12430
                     /gene="mfd"
                     /locus_tag="ACF4ZO_001456"
     CDS             8927..12430
                     /gene="mfd"
                     /locus_tag="ACF4ZO_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HFD5486979.1"
                     /translation="MDILELFSQNKKVQSWHSGLTTLGRQLVMGLSGSSKALAIASAY
                     LDDQKKIVVVTSTQNEVEKLASDLSSLLDEELVFQFFADDVAAAEFIFASMDKALSRI
                     ETLQFLRNPKSQGVLIVSLSSLRTLLPNPDVFTKSQIQLTVGEDYDSDTLTKQLMTIG
                     YQKVSQVISPGEFSRRGDILDIYEITQELPYRLEFFGDDIDSIRQFYPETQKSFEQLE
                     GIFINPASDLIFEASDFQRGIEQLEKALQTAQDDKKSYLEDVLAVSKNGFKHKDIRKF
                     QSLFYEKEWSLLDYIPKGTPIFFDDFQKLVDKNARFDLEIANLLTEDLQQGKALSNLN
                     YFADNYRELRHYKPATFFSNFHKGLGNIKFDQMHQLTQYAMQEFFNQFPLLIDEIKRY
                     QKNQTTVIVQVESQYAYERLEKSFQDYQFRLPLVSANQIVSRESQIVIGAISSGFYFA
                     DEKLALITEHEIYHKKIKRRARRSNISNAERLKDYNELAVGDYVVHNVHGIGRFLGIE
                     TIQIQGIHRDYVTIQYQNSDRISLPIDQIGSLSKYVSADGKEPKINKLNDGRFQKTKQ
                     KVARQVEDIADDLLKLYAERSQQKGFSFSPDDDLQRAFDDDFAFVETEDQLRSIKEIK
                     ADMESMQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVAVLVPTTVLAQQHYENFKA
                     RFENYPVEVDVLSRFRSKKEQAETLERVQKGQIDIIIGTHRLLSKDVVFSDLGLIVID
                     EEQRFGVKHKETLKELKTKVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPVQ
                     TYVLENNPGLVREAIIREMDRGGQIFYVYNKVDTIEKKVAELQELVPEASIGFVHGQM
                     SEIQLENTLIDFINGDYDVLVATTIIETGVDISNVNTLFIENADHMGLSTLYQLRGRV
                     GRSNRIAYAYLMYRPDKILTEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNILGA
                     SQSGFIDSVGFEMYSQLLEQAIASKQGKTTVRQKGNTEINLQIDAYLPDDYIADERQK
                     IDIYKRIREIQSREDYLNLQDELIDRFGEYPDQVAYLLEIALLKHYMDNAFAELVERK
                     NNQVIVRFEVTSLTYFLTQDYFEALSKTHLKAKISEHQGKIDIVFDVRHQKDYRILEE
                     LMLFGERLSEIKIRKNNSVFK"
     gene            12592..12864
                     /locus_tag="ACF4ZO_001457"
     CDS             12592..12864
                     /locus_tag="ACF4ZO_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HFD5486980.1"
                     /translation="MRLDKYLKVSRLIKRRSVAKEVADKGRIKVNGILAKSSTNVKLN
                     DHIEISFGNKLLTVRVIEIKDSTKKEDALKMYEIISETRITLNEEA"
     gene            12851..13222
                     /locus_tag="ACF4ZO_001458"
     CDS             12851..13222
                     /locus_tag="ACF4ZO_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HFD5486981.1"
                     /translation="MKKPSIVQLNNHYIKKENLKKKFEEEESQKRNRFMGWILVSMMF
                     LFILPTYNLVKSYVDFEKQNQQVVKLKKEYNELSKSTKKEKQLAERLKDDNFVKKYAR
                     AKYYLSREGEMIYPIPGLLPK"
     gene            13219..13344
                     /locus_tag="ACF4ZO_001459"
     CDS             13219..13344
                     /locus_tag="ACF4ZO_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0009 family protein"
                     /protein_id="HFD5486982.1"
                     /translation="MMMDNIIKKIEAFLAFSDKKLAELQQENQKVKEESQYIQKN"
     gene            13357..14643
                     /locus_tag="ACF4ZO_001460"
     CDS             13357..14643
                     /locus_tag="ACF4ZO_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HFD5486983.1"
                     /translation="MRKLLAAMLMTFFLTPLPVISTEKKLIFSKNAVYQLKQDVVQST
                     QFYNQLPSNPNLYQETCAYKDSDLTLPAGRLGVNQPLLIKSLVLNKESLPVFELADGT
                     YVEANRQLIYDDIVLNQVDIDSYFWTQKKLRLYSAPYVLGTQTIPSSFSFAQKVHATQ
                     MAQTNHGTYYLIDDKGWASQEDLVQFDNRMLKVQEMLLQKYNNPNYSIFVKQLNTQTS
                     AGINADKKMYAASISKLAPLYIVQKQLQKKKLAENKTLTYTKDVNHFYGDYDPLGSGK
                     ISKIADNKDYRVEDLLKAVAQQSDNVATNILGYYLCHQYDKAFRSEIKALSGIDWDME
                     QRLLTSRSAANMMEAIYHQKGQIISYLSNTEFDQQRITKNITVPVAHKIGDAYDYKHD
                     VAIVYGNTPFILSIFTNKSNYEDITAIADDVYGILK"
     gene            14640..15926
                     /gene="tilS"
                     /locus_tag="ACF4ZO_001461"
     CDS             14640..15926
                     /gene="tilS"
                     /locus_tag="ACF4ZO_001461"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016879 - ligase activity, forming
                     carbon-nitrogen bonds [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HFD5486984.1"
                     /translation="MMTYQEIFNEIKNKAYFKNHRHVLIAVSGGVDSMNLLHFLYLFQ
                     DKLKIRIGIAHVNHKQRSESDSEEAYLKCWAKKHDIPIYVSNFEGIFSEKAARDWRYA
                     FFKSIMLKNNYSALVTAHHSDDQAETILMRLIRGSRLRHLSGIKSVQPFANGQLIRPF
                     LTFSKKDLPEIFHFEDSSNRELSFLRNRVRNNYLPLLKQENPRFIQGLNQLALENSLL
                     FQAFKELTNHITTTDLTEFNEQSKSIQYFLLQDYLEGFPDLDLKKSQFTQLLQIIQIA
                     KQGYYYLKKDYYIFIDKFSFKITKIVPKTELVKEEKMLEYDSNLCYRDYYFSFMPKSN
                     EDQGQVNIPLFSLSSIKLRSRQSGDYISFGHFSKKIRRLFIDEKFTIAERQNAIVGEQ
                     DGEIIFVLVGDKTYLRKACKHDIMLAKLYIDKLEKG"
     gene            15931..16473
                     /gene="hpt"
                     /locus_tag="ACF4ZO_001462"
     CDS             15931..16473
                     /gene="hpt"
                     /locus_tag="ACF4ZO_001462"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012961310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006166 - purine ribonucleoside salvage
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HFD5486985.1"
                     /translation="MLEQDIQKILYSENDIIRKTKKLGEQLTKDYQEKNPLMIGVLKG
                     SVPFMAELMKHIDTHVEIDFMVVSSYHGGTSSSGEVKILKDVDTNIEGRDIIIVEDII
                     DTGRTLKYLRDMFKYRKANTIKIATLFDKPEGRVVKIEADYVCYNIPNEFIVGFGLDY
                     AENYRNLPYVGVLKEEVYSK"
     gene            16495..18474
                     /gene="ftsH"
                     /locus_tag="ACF4ZO_001463"
     CDS             16495..18474
                     /gene="ftsH"
                     /locus_tag="ACF4ZO_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HFD5486986.1"
                     /translation="MKNNKNNGFVKNSFIYILMIIVVITGFQFYLKGTSTQSQQISYS
                     KLIKHLKAGDIKSLSYQPSGSIIEVKGKYEKPQKVTVNSGLSFLGGRASTQVTEFSSL
                     VLPSDTILKEMTAAADKNGTELTVKQESSSGTWITFLMSFLPIVIFAAFMMMMMNQGG
                     GGARGAMSFGKNKAKSQSKGDVKVRFTDVAGAEEEKQELVEVVDFLKNPKKYKSLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAERAIIFIDEIDAVGRRRGAGMGGGNDEREQTLNQLLIEMDGFEGNENIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILRVHAKNKPLANDVNLKVVAQQTPGFV
                     GADLENVLNEAALVAARRNKIKIDASDIDEAEDRVIAGPSKKDRTISQKEREMVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDLKEQLAGLMGGR
                     VAEEIVFNAQTSGASNDFEQATQIARAMVTEYGMSEKLGPVQYEGNHAMMPGQISPEK
                     AYSAQTAQMIDDEVRELLNQARNQAADIINENRDTHKLIAEALLKYETLDAAQIKSIY
                     ETGKMPVDLETDDNEAHALSYDEIKNKMTESESAE"
BASE COUNT         6522 a         2893 c         3378 g         5910 t
ORIGIN      
        1 atgcaatagg atactgactg atgagatgcg tgacagcacg gttaatggtt tgggactgct
       61 tgtcttctag cttaactcct agtgcatagc gtgtctggcg ctctaccaaa gtcaacataa
      121 cagcttcacc tttggttttc ttgccgagaa ccaaatcaat ctcccaatgc ccaaattcag
      181 aacgatcatt aatatattct ggacgttctt cgatagattt acctaaagtc ttcttattcg
      241 ttttcatgac tttcttagaa cgttttctaa tactaaccat cttaggcaaa tcgattggtt
      301 tcatagacac gttgtccact atcagcgaaa taggcgttga agaaggtttg ttttccattc
      361 ttatccttta cctgatctac tgaaccacgt tttatttctc ggcagattgt agaacggtga
      421 ctacccagaa gtcgagcaat ctcaacgggt ttctttccca ttttgagata agcagcaatt
      481 tcaccccgtt ctgtggctga aagatgagaa taggaggatt ttctggtaga attaatatta
      541 gacatgttca tctgctttcc atactgaatt ggggaattct agtatatcag acgaacatgt
      601 cttttttgtt gcacttcatt ttacaacgcg ggatataatg ttattttcta gtttttttaa
      661 aataaatatt gacagtttta gataattttt gttaaaatga tgtggttaag gtctcatagc
      721 tcagctggat agagcattcg ccttctaagc gaacggtcgc aggttcgaat cctgctggga
      781 tcaaagataa aaaagcactg ttttagtgct ttttttgtat ttaccttagt gtattgaaaa
      841 gataggattt agtctgtctt tttttaatat ttgcttttaa ttataccgaa ctattatcta
      901 ataaagtggt aagagttagt tattccagtt cacactctct tacttatgat aaggactgcc
      961 ttgtgtaatc ataaaagcac gataaatttg ctcagtaaga actagacgca ttaactgatg
     1021 aggtaaggtt aacaatccaa aactcattag catattagct ctttttttaa taattgaatc
     1081 taatccaaga cttccaccaa taataaacgt gatagttgaa tatcccttaa cagtaacccc
     1141 tgatattaat tcactaaatg tctctgaagg aaactgtttt ccttcaatag ctaatgcaat
     1201 tacaaaatca cgttccccaa tttttttatg gattcgctga gcttctttac tcataatcaa
     1261 ttgattatca gcaaaacttg ctttatctgg tgttctttca tcagttaact caatcatttc
     1321 gaattgacaa aaacgggaaa gtcttttttg atattctgaa ataccatctt tgaggtatct
     1381 ttcttttagt tttccaacac aaattagttt tactttcata gcttaattgt atcacaagaa
     1441 cattactttt tacacaattt atccacaagt tatttttctt caactactaa taaaaacctt
     1501 tgtacaaagg tctttattag taaaaagaaa agtaatccac agcctgtgga ttacttttct
     1561 tttttttatt tttaaggtat aattaagcaa agttctataa gctatggaca aataattcgg
     1621 aggacaaaac atgccaagta tgaaacatat cttaaaatcc ttaagtattt tactagttgg
     1681 atttttagga ggattaatag caattattac attcaataat ctctacccac attctccttc
     1741 aaaaataaat tcaggtaagg caacaactag taatatggtt tttaacaaca caaccaatac
     1801 tactaaagct gtcaaagctg ttcaaaatgc agttgtatca gttattaatt atcaagataa
     1861 cccttcttca tccctttcta acccttatac aaaactcttt ggagaagggc gttcaaaaga
     1921 gaataaggat gctgaattat ctatttttag tgaaggatct ggggtcattt atcgaaaaga
     1981 tggcaactcc gcttacgttg ttactaataa ccatgttatc gacggagcta aacggattga
     2041 aattcttatg gcagacggat ctaaagttgt tggtgaatta gttggagctg atacttattc
     2101 ggatttagct gttgttaaga tctcttcaga taagataaaa acagtagctg aatttgcaga
     2161 ctctacaaaa ctaaatgttg gagaagttgc tattgctatc ggcagcccac taggaacaca
     2221 atacgctaat tctgttactc aaggaatcgt ctctagttta agtcgtactg taactttaaa
     2281 aaacgagaat ggtgagactg tctcaacaaa tgctattcag acagatgctg ctattaaccc
     2341 tggaaactct ggtggaccac taattaatat tgaggggcaa gtaatcggaa ttaattcaag
     2401 taaaatttct tctaccccaa ctggtagcaa cggtaatagt ggtgctgttg aaggaattgg
     2461 ttttgctatc ccatctactg acgttattaa aattattaaa caactagaaa ctaatggtga
     2521 agttatcaga cctgctcttg gaatatccat ggtcaattta aatgacttat ccacaaatgc
     2581 tcttagccaa attaatattc caactagtgt aactggtggt attgtagtag cagaagttaa
     2641 ggaaggaatg ccggcatctg gcaaacttgc tcagtacgat gtgattacag aaattgatgg
     2701 caaaacagtt aattcaatta gtgatttaca aagtagtcta tacggacacg atattaatga
     2761 tactattaaa gtaacttttt atagaggaac tacaaagaaa aaagcagata tcaaattaac
     2821 aaaaactact caagatttga ctaaaacgca gtaaacaagc tacctaaata ctattacatt
     2881 ttatcacata aaacagtcca aaggactgtt ttatgtttct tattctatcc aggaactccc
     2941 ttatgacaaa agaattattg atagacctac caattgaaga tattgttaca aatccctatc
     3001 agccaaggat acaatttaat caaagagaac tccaagacct agcaacttct attaaatcaa
     3061 acggcctcat tcaacctatt attgttcgaa aatctgacat ttttggctat gagttagttg
     3121 ctggagaacg acgacttaaa gcttcaaaaa tggctggtct aaaaaaaatt ccagctatca
     3181 tcaagaagat ctctacactc gagagcatgc aacaagctat agttgaaaat ttacaacgtt
     3241 ctaaccttaa cgctatcgaa gaagctaaag cctatcagtt attggttgaa aaaaaacaca
     3301 tgactcacga tgagattgct aaatatatgg gaaaatcaag accttatatt agcaatacct
     3361 tacgtctgtt acaactccca gcacctatca ttaaagcaat tgaagaagga aaaattagtg
     3421 cgggacacgc gcgtgctctt ttaactttga gtgatgataa gcaacaactg tacctcactc
     3481 ataaaataca aaatgaaggc ctaagtgtta ggcaaattga gcaactggtt acttctaccc
     3541 caagttcgaa gctatctaaa aaaactaaaa atatttttgc cacttcttta gagaaacaat
     3601 tggctaaatc attgggactc tctgtcaata tgaagctgac agcaaaccat agtgggtacc
     3661 ttcagatatc tttttccaat gatgatgaat taaacagaat tatcaacaag ctaaagtagc
     3721 ttgttgatat tctgtttttt cttttttagt tttccacata aaaaatagtt gaaaacaata
     3781 gcggtgtcac cttaaaatgg cttttccaca ggttgtggag aacccaaatt aacagtgtta
     3841 atttattttc cacaggttgt ggaaaactag aatagtttat ggtagaatag ttctagaatt
     3901 atccacaaga aggaacctag tatgactgaa aatgaacaaa ttttttggaa cagggtcttg
     3961 gaattagctc agagtcaatt aaaacaggca acttatgaat tttttgttca tgatgcccgt
     4021 ctattaaagg tcgataagca tattgcaact atttacttag atcaaatgaa agaactcttt
     4081 tgggaaaaaa atcttaaaga tgttattctt actgctggtt ttgaagttta taacgctcaa
     4141 atttctgttg actatgtttt cgaagaagac ctaatgattg agcaaaatca gaccaaaatc
     4201 aatcaaaaac ctaagcagca agccttaaat tctttgccta ctgttacttc agatttaaac
     4261 tcgaaatata gttttgaaaa ctttattcaa ggagatgaaa atcgttgggc tgttgctgct
     4321 tcaatagcag tagctaatac tcctggaact acctataatc ctttgtttat ttggggtggc
     4381 cctgggcttg gaaaaaccca tttattaaat gctattggta attctgtact attagaaaat
     4441 ccaaatgctc gaattaaata tatcacagct gaaaacttta ttaatgagtt tgttatccat
     4501 attcgccttg ataccatgga tgaattgaaa gaaaaatttc gtaatttaga tttactcctt
     4561 attgatgata tccaatcttt agctaaaaaa acgctctctg gaacacaaga agagttcttt
     4621 aatactttta atgcacttca taataataac aaacaaattg tcctaacaag cgaccgtaca
     4681 ccagatcatc tcaatgattt agaagatcga ttagttactc gttttaaatg gggattaaca
     4741 gtcaatatca cacctcctga ttttgaaaca cgagtggcta ttttgacaaa taaaattcaa
     4801 gaatataact ttatttttcc tcaagatacc attgagtatt tggctggtca atttgattct
     4861 aatgtcagag atttagaagg tgccttaaaa gatattagtc tggttgctaa tttcaaacaa
     4921 attgacacga ttactgttga cattgctgcc gaagctattc gcgccagaaa gcaagatgga
     4981 cctaaaatga cagttattcc catcgaagaa attcaagcgc aagttggaaa attttacggt
     5041 gttaccgtca aagaaattaa agctactaaa cgaacacaaa atattgtttt agcaagacaa
     5101 gtagctatgt ttttagcacg tgaaatgaca gataacagtc ttcctaaaat tggaaaagaa
     5161 tttggtggca gagaccattc aacagtactc catgcctata ataaaatcaa aaacatgatc
     5221 agccaggacg aaagccttag gatcgaaatt gaaaccataa aaaacaaaat taaataacat
     5281 gtggaaaaga atatctttta tgaaatagtt atccacaagt tgtgaacaac catttagtct
     5341 tggattctct cgtttattta gagttatcca ctatatacac aagacctact actactactt
     5401 attattatac ttattaaata aaggagttct catgattcaa ttttcaatta atcgcacatt
     5461 atttattcat gctttaaatg caactaaacg tgctattagc actaaaaatg ctattcctat
     5521 tctttcatca ataaaaatta aagtcactcc tacaggagta actttaacag ggtctaacgg
     5581 tcaaatatca attgaaaaca ctattcctgt aagtaatgaa aatgctggtt tgctaattac
     5641 ctctccagga gctattttat tagaagctag tttttttatt aatattattt caagtttgcc
     5701 agatattagt ataaatgtta aagaaattga acaacaccaa gttgttttaa ccagtggtaa
     5761 atcagagatt accttaaaag gaaaagatgt tgaccagtat cctcgtctac aagaagtatc
     5821 aacagaaaat cctttgattt taaaaacaaa attattgaag tctattattg ctgaaacagc
     5881 ttttgcagcc agtttacaag aaagtcgtcc tattttaaca ggagttcata ttgtattaag
     5941 caatcataaa gattttaaag cagtagcgac tgactctcat cgtatgagcc aacgtttaat
     6001 cactttggac aatacttcag cagattttga tgtggttatt ccaagtaaat ctttgagaga
     6061 attttcagca gtatttacag atgatattga gaccgttgag gtatttttct caccaagcca
     6121 aatcttgttc agaagtgaac acatttcttt ttatacacgc ctcttagaag gaaattatcc
     6181 cgatacagac cgtttattaa tgacagaatt tgagacggag gttgttttca atacccaatc
     6241 ccttcgccac gctatggaac gtgccttctt gatttctaat gctactcaaa atggtactgt
     6301 taagcttgag attactcaaa atcatatttc agctcatgtt aactcacctg aggttggtaa
     6361 ggtaaacgag gatttagata ttgttagtca gtctggtagt gatttaacta tcagcttcaa
     6421 tccaacttac cttattgagt ctttaaaagc tattaaaagt gaaacagtaa aaattcattt
     6481 cttatcacca gttcgaccat tcaccctaac accaggcgat gaggaagaaa gttttatcca
     6541 attaattaca ccagtacgaa caaactaagt aagaaaaagc tcccttttag gagttttttt
     6601 gttattataa atattaacga taatataagt ggagaaaagt gaatgtatca aattggatca
     6661 tttgttgaaa tgaaaaaacc tcatgcttgt gtaattaaag aaactggtaa aaaggctaat
     6721 caatggaagg tactgagagt aggagctgat attaaaattc agtgtactaa ctgtcagcat
     6781 gtgattatga tgagtcgtta tgattttgat cgaaaattaa aaaaagtact gcaaccatga
     6841 aagtcctttt aaataaataa ttctagctat atttgcaacc aatactttcc taaaaaattg
     6901 ttagtatgcc gttggaaaat tagctattct aatgttatcg aaagaagaaa ggtggctatt
     6961 gacaatgacg aaagttgtag cacagttact tagtttctcg gcaaactata tcaaaatgag
     7021 aataatacac caaactttga taatttaaat gaaggtgaaa gagtggcata atgataagca
     7081 aatctgaaat tttcttctta ttcataccgc tttttcttct attttttggt ataataatct
     7141 tgattgaaat ttgaatggag attcgctaaa tggctttaac agcaggtatt gtaggcttac
     7201 caaatgttgg taaatcaacc ttatttaacg caattacaaa agcaggagca gaagctgcta
     7261 attatccttt tgcgactatt gatcccaatg ttggtatggt agaggttcca gatgagcgtc
     7321 tgcaaaaatt gacagaattg attacaccta aaaaaacagt tccgacaacc tttgaattta
     7381 ctgatattgc aggtatcgtt aaaggtgctt ctagagggga aggtctagga aataaatttt
     7441 tagctaatat tcgtgaagtc gatgctattg ttcatgtggt acgtgctttt gatgatgaaa
     7501 atgtcatgcg tgaacaaggt cgtgaggatg ctttcgttga tcctatagca gatattgaca
     7561 ctattaatct tgaattaatc ttagctgatt tagagtcaat caataaacgt tatgcgcgtg
     7621 ttgaaaaaat ggcacgaact caaaaagata aagaatcagt agcagagttc aatgttttac
     7681 aaaagattaa acctgttttg gaagatggga aatcagctag gacaattgag tttacagaag
     7741 aggaagcaaa agttgttaaa ggtctctttt tattaacaac taaacctgtt ttatatgtag
     7801 ctaatgtcga tgaagataaa gttgctaatc cagatggtat tgattatgtc aaacaaattc
     7861 gtgactttgc agctactgaa aatgctgaag tagttgttat ctcagcgcgt gcagaagaag
     7921 aaatttcaga gcttgacgat gaggataaag aagaattttt ggaagctatc ggtcttactg
     7981 aatcaggcgt tgataaatta accagagcag cttatcatct cttaggcctt ggaacctatt
     8041 ttacagcagg tgaaaaagag gttcgtgctt ggacgtttaa gcgtggtata aaagctccac
     8101 aagctgctgg tattatccat tcagattttg aaagaggttt tattcgtgca gtaaccatgt
     8161 cttatgatga tctaatgatc tacggttcag aaaaagccgt caaagaagct ggacgcttgc
     8221 gtgaagaagg aaaagaatac gttgttcaag atggggacat catggaattc agatttaatg
     8281 tgtaattata ttaaaacaat atcagaaggt tggaagaaca ttccagccct tttggcattt
     8341 tagaaagaga aaatatggta aaaatgattg ttggtctggg aaatccaggc tctaaatatg
     8401 aaaaaacaaa gcacaatatt ggttttatgg ctattgacaa tattgtcaag aaccttgacg
     8461 ttacctttac agatgataaa aattttaaag cacagatagg aagtactttt attaatcatg
     8521 aaaaagttta ctttgtgaaa cctactactt ttatgaataa tagcggcata gcagtaaaag
     8581 cattactaac ctactataat attgacataa cagatttaat tgttatctat gatgatttag
     8641 acatggaagt cagtaaatta cgtttacgta gtaagggttc agcaggagga cataatggca
     8701 ttaagtcaat cattgcccac attggaactc aggaatttaa ccgaatcaaa gttggtattg
     8761 gacgaccttt aaaaggtatg actgttatta gccatgtgat gggccaattc aataccgaag
     8821 ataatattgc tatttcgtta actcttgaca gagttgtcaa tgctgtcaag ttttatttac
     8881 aagaaaatga ttttgaaaaa acaatgcaga aatttaatgg ataatcatgg atattttaga
     8941 attatttagt cagaataaga aagtccaatc ctggcactct ggattaacca ccttaggaag
     9001 acaactggta atggggttat cgggttcaag taaagcattg gctatagctt ccgcttattt
     9061 agatgatcaa aaaaaaatag ttgtggttac atcaactcaa aatgaggttg aaaaattagc
     9121 cagcgattta tctagtttac ttgatgaaga acttgttttc caattttttg cagacgatgt
     9181 ggctgcagcg gaatttatct ttgcgtcaat ggataaagct ctatcaagaa tagaaaccct
     9241 gcaattttta aggaatccta aatctcaggg cgttttaatt gttagtttat caagcttaag
     9301 aactttattg ccaaacccag atgtttttac aaagagtcag attcaactaa cagttggaga
     9361 agattatgat agtgatactc ttactaaaca actgatgaca attggctatc agaaggtctc
     9421 acaggtcatt agtccgggag aatttagccg tcgaggggat attttagata tctatgagat
     9481 tacacaagaa ttgccttatc gattggaatt ttttggcgat gatattgata gtattaggca
     9541 attttatcca gaaactcaaa aatcttttga acaactagaa ggtattttta ttaatccagc
     9601 aagtgatctt atttttgagg ctagtgattt tcaacgtggc attgagcaat tagaaaaggc
     9661 tctacaaaca gcacaagatg ataaaaaatc ttatttagaa gatgtattag ctgtttcaaa
     9721 aaacggtttt aaacataagg atatccgtaa atttcaatca ttattttacg aaaaagagtg
     9781 gtcattatta gattatattc ctaagggaac gccaatcttt tttgatgatt ttcaaaaact
     9841 agttgataaa aatgcaagat ttgatttaga gattgctaat ctcttgacag aagatttaca
     9901 gcaaggaaag gctctttcca atcttaacta ctttgcagat aattatcgag agcttaggca
     9961 ctataagcca gcgaccttct tttcaaattt tcataaggga cttggaaata tcaaatttga
    10021 tcagatgcat cagctaactc agtatgccat gcaggaattt tttaatcaat ttcctttgtt
    10081 gattgatgag attaaacggt atcaaaaaaa tcaaacaacg gttattgtac aggtagagtc
    10141 tcagtatgct tacgaacgac ttgaaaaatc ttttcaagat taccaatttc gccttccttt
    10201 agtgagtgct aatcaaattg tttcacgtga atcacaaatt gtaattggag ctatctccag
    10261 tggtttttat tttgctgatg aaaagttagc gttaatcaca gagcatgaaa tttatcataa
    10321 aaagatcaaa cgacgcgcta gacgatctaa tattagcaat gctgagcgtt tgaaagatta
    10381 caatgagtta gcagtaggtg attacgtggt tcataatgtc catggtatcg gtcgctttct
    10441 tggaattgaa acgattcaga ttcagggaat ccatcgagat tacgttacta ttcaatatca
    10501 aaattcagac cgtatttctc ttccaattga ccaaattggt agcttatcaa agtacgtttc
    10561 tgctgatgga aaagaaccta aaattaataa actcaatgat ggtcgttttc aaaagacaaa
    10621 gcaaaaggtc gctagacaag tagaagatat tgctgatgac cttctaaaat tatatgctga
    10681 aagaagtcag caaaaaggat tttcattttc accagatgat gacttgcagc gcgcttttga
    10741 tgatgatttt gcttttgtag aaacagaaga tcaacttagg tctataaagg aaattaaagc
    10801 tgatatggag agcatgcaac ctatggatcg tcttttagta ggcgatgtag gatttggtaa
    10861 gacagaagta gctatgaggg cagcctttaa agcggtgaat gatcacaaac aagtagctgt
    10921 cttagttcca accacagtct tggcccagca gcattatgaa aacttcaaag cacgctttga
    10981 aaattaccct gttgaggttg acgtcttaag tcgtttccgt agtaaaaaag agcaagctga
    11041 aacactagaa cgtgtacaaa aaggtcaaat tgacattatt atcggaaccc atcgactcct
    11101 atcaaaagat gtggtctttt ctgatttagg attaattgtg attgatgagg aacaacggtt
    11161 tggtgttaag cataaagaaa ctttaaagga attaaaaact aaggttgacg tcttaacctt
    11221 aacagctact ccgattccta gaaccttaca catgtctatg ttaggtatcc gagatttatc
    11281 ggttattgag accccaccaa ccaatcgtta tcctgttcaa acctatgttt tggaaaataa
    11341 tccaggtctc gttagagaag ctatcattcg tgaaatggat cgtggaggac aaatttttta
    11401 cgtttacaat aaagttgaca ctattgaaaa gaaagttgca gagctacaag aattagtccc
    11461 agaagcttct atcggttttg ttcatgggca aatgagtgaa attcaacttg aaaatacctt
    11521 gattgacttt ataaatggtg attatgatgt ccttgtggct acaacaatca tcgaaacagg
    11581 agttgacatt tctaatgtaa acactttgtt tattgagaat gctgatcata tgggattgtc
    11641 aactttatat caactgaggg ggcgcgtcgg aagaagtaat cgtattgcct atgcttacct
    11701 gatgtatcgt cctgataaga tcctaacaga agtctctgaa aaacgtttag aggctattaa
    11761 aggctttact gaattaggtt caggcttcaa gattgctatg cgagatttgt ctatacgagg
    11821 agcaggtaat attttaggag cttctcaaag tggctttatt gattcggtcg gttttgaaat
    11881 gtattctcag ttattggaac aggctattgc tagcaagcaa ggaaaaacga ctgttcgcca
    11941 aaaaggtaat actgaaatca atcttcagat tgatgcttat ttaccagatg attatattgc
    12001 agatgagcgc caaaaaattg acatttacaa gcgtattcga gaaattcaat caagagaaga
    12061 ttatctcaat ttgcaagatg agctgataga tcgttttgga gagtatcctg atcaagttgc
    12121 ctatttgtta gagatagctc tgctaaaaca ttatatggac aatgcctttg cggaattagt
    12181 tgaacgcaaa aataatcagg tcattgttcg atttgaagta acttctttaa cttatttctt
    12241 gactcaggat tatttcgaag ccttatcgaa aacccatctt aaagctaaaa ttagtgaaca
    12301 tcaggggaaa atcgatatcg tctttgacgt tcgccatcaa aaagattata gaattttaga
    12361 agaattgatg ttatttggag aaaggcttag tgagataaaa atcagaaaaa acaattcagt
    12421 ttttaaataa taatttgaaa caacttttag actgaatagt attaatgaca atggaacgaa
    12481 ctagctcttt atacttttgt caaaaatcta agatctttgc tgcgaaatta ggatcttttc
    12541 taccatttaa aaaataaaaa tgataaaatg aagaggattg taggagaaat tatgagacta
    12601 gataaatatc taaaggtatc gcgccttatt aaacgtcgtt cagtagcaaa agaagttgcg
    12661 gataagggac gaattaaagt taatgggata cttgctaaaa gttcaacgaa tgtaaaacta
    12721 aatgatcaca ttgaaattag ttttggaaat aaattactga cagtaagagt cattgaaata
    12781 aaagatagta caaaaaaaga agatgctctt aagatgtatg agataatcag tgaaacaagg
    12841 ataacattaa atgaagaagc ctagtattgt tcaattaaat aatcattata ttaagaaaga
    12901 gaatctcaaa aaaaaatttg aagaagaaga atctcaaaaa agaaatcgtt ttatgggatg
    12961 gatccttgta agtatgatgt ttttatttat tttgccaact tataatcttg tcaaaagtta
    13021 tgttgatttt gaaaagcaaa atcaacaggt ggttaaatta aaaaaagagt ataatgaatt
    13081 gtcaaagagt acaaaaaaag aaaaacaatt agcagaacga ctaaaagatg ataattttgt
    13141 caaaaaatat gctagggcaa aatactattt atcgcgtgaa ggagaaatga tttatcctat
    13201 tccaggacta ttaccaaaat gatgatggac aatattataa aaaaaataga agcatttctt
    13261 gctttttctg ataaaaaatt agcagagctg caacaggaaa atcaaaaagt taaagaagaa
    13321 agtcagtata ttcaaaaaaa ctagaaagga gtcaatatga gaaaattatt agcggctatg
    13381 ttaatgactt tttttctgac tcctttacca gtaattagta cagaaaaaaa acttatattt
    13441 tcaaaaaatg ctgtttatca attgaaacaa gatgtcgttc aatcaacaca attctataat
    13501 caactaccct ctaatccaaa tctttatcaa gaaacgtgtg cttataaaga cagtgattta
    13561 actctaccag caggaagatt aggtgtaaat caaccattac ttattaaatc gcttgtgctt
    13621 aacaaagaat ctttaccggt ttttgagtta gctgatggta cctatgttga ggctaatcga
    13681 caattgattt atgacgatat tgtacttaat caagtagata tagatagcta tttttggaca
    13741 caaaagaaac ttaggcttta ttcagcccct tatgttttag gtacacaaac aattccttct
    13801 tctttttcat ttgctcaaaa agttcatgcc actcaaatgg cacaaacaaa ccatggaact
    13861 tattatctta ttgatgataa gggctgggca tcacaagaag atctagttca atttgataac
    13921 cgcatgttaa aagtccagga aatgctctta caaaaatata ataacccaaa ttattcaatt
    13981 tttgtaaagc aactcaacac acaaacaagt gctggtatta atgctgataa aaaaatgtat
    14041 gctgcaagta tctcgaagtt agcaccactt tatattgttc aaaaacaatt acaaaaaaag
    14101 aaattagcag agaataaaac tttgacttat actaaagatg ttaatcattt ttatggagac
    14161 tatgatccat tgggaagtgg taaaattagt aaaatagctg ataataaaga ttatcgtgtt
    14221 gaagacctac tgaaagctgt agcacaacaa tcggataatg tagcaactaa tattttaggt
    14281 tattatctat gtcatcagta tgataaagct ttccgctcag agataaaagc tttatcaggt
    14341 atcgattggg atatggagca gcgcttatta acttctcgtt cagctgcaaa tatgatggaa
    14401 gctatttatc atcaaaaagg ccaaattatt tcttaccttt caaataccga atttgatcaa
    14461 caacgtatca caaaaaatat tactgttcca gttgcacata aaattggtga tgcttatgat
    14521 tataaacatg acgttgctat tgtttacggt aatactccat ttattttgtc tatttttaca
    14581 aataaatcaa actatgaaga tattacggct attgcagatg acgtttatgg tattttaaaa
    14641 tgatgaccta tcaagaaatt tttaatgaaa taaaaaataa agcctacttt aaaaatcata
    14701 gacatgtgtt aatagccgta tctggtggag tagattcaat gaatttattg cactttttat
    14761 acctgtttca agacaaattg aaaattcgta ttggtattgc tcatgttaat cacaaacaaa
    14821 gatcagaatc agattcagaa gaagcttatt taaagtgttg ggctaaaaaa catgacatac
    14881 ctatttatgt ttctaatttt gaaggaatat tttcagaaaa agcagcacgt gattggcgct
    14941 atgctttttt taagagtatt atgttaaaaa ataactattc agctttagta acagctcacc
    15001 attcagatga tcaagcagaa actattttga tgaggctaat tagaggaagc cgattgaggc
    15061 acttgtcggg tataaaaagc gtgcaaccat ttgccaatgg tcaacttata agaccttttt
    15121 taactttctc aaaaaaggac ttgccagaaa tttttcattt tgaagattct tcaaataggg
    15181 aattatcatt tttaagaaat agagttagaa ataattattt accattgtta aagcaggaaa
    15241 atcctaggtt cattcaggga ttaaatcaat tagcacttga aaatagctta ctttttcaag
    15301 cttttaagga gctaacaaat catattacta ccactgattt aacagaattt aatgagcaat
    15361 ctaagtctat tcaatacttt ttgttacaag attatttaga aggttttcca gatttagatt
    15421 taaaaaaatc tcaatttact caattattgc aaattatcca aattgctaaa caaggctatt
    15481 attatctcaa aaaagactat tatatattca ttgataagtt ctcttttaaa attacaaaaa
    15541 tcgttcctaa gactgagtta gttaaagaag aaaaaatgtt agaatacgat agtaacttat
    15601 gctacagaga ttattatttt tcatttatgc caaaaagtaa cgaagatcaa ggacaggtaa
    15661 atataccttt atttagttta tcgtctatta aattaagaag tcgccaatct ggagattata
    15721 tttcttttgg tcacttttca aaaaaaataa gacgtttatt tatagatgaa aaattcacaa
    15781 tagctgaacg gcaaaatgct attgtaggag aacaagatgg agagattatt tttgtattag
    15841 tcggtgataa aacttatttg agaaaagctt gtaaacatga tataatgttg gctaaactgt
    15901 atattgataa attagaaaaa gggtgacagc atgcttgagc aagatattca aaaaattctt
    15961 tactctgaaa atgatattat tcggaaaact aaaaaattag gagaacaatt aacaaaagat
    16021 tatcaagaaa aaaatccgct tatgattggt gtattaaaag gatcagttcc ttttatggca
    16081 gaactaatga aacacatcga tactcatgtt gaaattgatt ttatggtagt atcaagttat
    16141 catggcggta catctagcag tggtgaagtt aaaattttaa aagatgtaga taccaatatt
    16201 gaaggaagag atatcataat tgttgaagat attattgaca ccggtcgcac cttaaaatat
    16261 ttacgagata tgtttaagta ccgtaaagct aatactatca aaattgcaac actgtttgat
    16321 aaacctgaag gtcgtgttgt taaaattgaa gcagattatg tttgttacaa tattccaaat
    16381 gaatttatcg taggctttgg tttagattac gcagaaaatt atcgcaatct tccttatgta
    16441 ggtgtattaa aagaagaagt ctattcaaaa tagaaaaagg tcaatgttta ctgtatgaaa
    16501 aataataaaa ataatggttt tgttaaaaat tcttttatat atatattgat gattatagtt
    16561 gtcatcacag gatttcaatt ttatcttaag ggaaccagca cacaaagcca acagattagt
    16621 tattccaaat taattaaaca tcttaaggct ggagatataa aatctttaag ttatcagcct
    16681 agcggtagta ttattgaagt taaagggaaa tacgagaaac ctcaaaaagt gacagttaat
    16741 tcaggactat catttttagg tggaagagct tcaacacagg taacagagtt ctcatcttta
    16801 gtattaccta gtgataccat cttgaaagaa atgacagcag cagctgataa aaatggaaca
    16861 gagcttacag ttaagcagga aagttcaagt ggtacttgga ttaccttctt aatgagcttt
    16921 ttacctattg ttatttttgc tgcttttatg atgatgatga tgaatcaagg tggtggagga
    16981 gctcgtggtg ctatgagttt cggcaaaaat aaggcaaaat ctcaatcaaa aggtgatgtt
    17041 aaagtgagat ttacagacgt tgctggtgcc gaagaagaaa aacaagaatt agtagaagtt
    17101 gttgattttt tgaaaaatcc taaaaaatat aaatcactag gagcacggat tccagcggga
    17161 gttcttctag aggggcctcc aggtactggt aaaacattac tagctaaagc tgtagcaggt
    17221 gaagctggag tgccattttt cagtatttca ggttcagatt ttgtcgaaat gtttgtcggt
    17281 gtaggtgcta gtcgtgttcg ttctttattt gaggatgcta aaaaagctga gcgtgcgatc
    17341 atctttatcg atgaaattga cgctgtaggt cgtcgtcgtg gtgctggcat gggaggcggt
    17401 aacgatgaac gagaacagac ccttaaccaa ttactcattg aaatggatgg ttttgagggt
    17461 aatgagaaca ttatcgttat tgctgcaact aaccgtagtg atgttttaga tccagcgtta
    17521 ctaagaccgg gtcgttttga tcgtaaggtt ttagttggtc gccctgatgt taaaggacgt
    17581 gaagccattt tacgtgttca tgctaaaaat aaaccacttg caaatgacgt taatttgaaa
    17641 gtagtagccc aacagactcc aggttttgta ggtgctgatc ttgaaaatgt tttaaatgaa
    17701 gctgcgttgg ttgctgctcg cagaaataaa attaaaattg atgctagtga tattgatgaa
    17761 gctgaagatc gtgttattgc tggaccatca aagaaagatc gcactatttc gcaaaaagag
    17821 cgagaaatgg ttgcttatca cgaagctggt catactattg ttggtttagt tttatctaat
    17881 gcgcgtgtag ttcacaaggt aactattgta cctcgtggac gagcaggtgg ttatatgatc
    17941 gctcttccaa aagaagatca aatgcttctt tctaaagaag atctgaaaga gcaattagca
    18001 ggattgatgg gtggtcgtgt tgctgaagaa attgttttta atgctcaaac atcaggtgcg
    18061 tcaaatgact ttgagcaagc tactcagata gcaagggcca tggttacgga atatggtatg
    18121 agtgaaaagc ttggaccagt tcaatatgaa ggtaaccatg cgatgatgcc aggacagatc
    18181 tctcctgaaa aagcttactc tgcccaaaca gctcaaatga ttgatgatga ggttcgtgaa
    18241 ctcttaaatc aagctcgtaa tcaagcagct gatatcatca atgagaatcg agatactcat
    18301 aaattgattg ctgaagctct tctcaaatat gaaactctag acgctgcaca aattaaatca
    18361 atttatgaaa ctggtaaaat gccagttgat ttagaaactg atgataatga agctcatgcg
    18421 ttatcttatg acgaaattaa aaataaaatg acagaatctg aatctgcaga atgatataaa
    18481 aaagctgaac ttatagatta agttcagctt ttttatcaac acaatatcct tgtaaacgtt
    18541 atgaattgta ataggtgcct aattgctaga aatgagaaga tgacatactt ttttttcttt
    18601 attacttaaa gtgagaaaga ctttggtatt taaaactaga aaattgttaa agccatttga
    18661 aaaaatctat tagtgttttc ttagaataat agaagaacag aag
//
LOCUS       DAXMQE010000035        18144 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.035, whole genome shotgun sequence.
ACCESSION   DAXMQE010000035 DAXMQE010000000
VERSION     DAXMQE010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18144)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18144)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18144
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.035"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            complement(<1..716)
                     /locus_tag="ACF4ZO_001464"
     CDS             complement(<1..716)
                     /locus_tag="ACF4ZO_001464"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015055932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008964 - phosphoenolpyruvate carboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA];
                     GO_process: GO:0015977 - carbon fixation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HFD5486987.1"
                     /translation="MPLKKLESSNNQAIIAEEVALLKEMLENITRRMIGDDAFTVIES
                     IMVLSEKQDYIELEKVVANISNQEMEVISRYFSILPLLINISEDVDLAYEINYQNNTD
                     TDYLGKLALTIKDLAGKDNGKDILEQVNVVPVLTAHPTQVQRKTILELTTHIHKLLRK
                     YRDAKAGVISLEKWRQELYRYIEMIMQTDIIREKKLQVKNEIKNVMQYYDGSLIQAVT
                     KLTTEYKNLAQKHGLELDNP"
     gene            911..2710
                     /gene="pepF"
                     /locus_tag="ACF4ZO_001465"
     CDS             911..2710
                     /gene="pepF"
                     /locus_tag="ACF4ZO_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HFD5486988.1"
                     /translation="MELKKRSEFPENELWDLTALYKDRQDFLLAIEKALQDIDLFKRN
                     YEGRLTSVDDFTQALIEIEHIYIQMSHIGTYAFMPQTTDFSDESFAQIAQAGDDFMTK
                     ANVALSFFDTALANADLDVLDTLEKNPYFSAAIRMAKIQKEHLLSPDVEKALANLREV
                     INAPYDIYTKMRASDFDMDDFEVDGKTYKNSFVSYENFYQNHENAEIREKAFRSFSNG
                     LRKHQNTAAAAYLAKVKSEKLLADMKGYASVFDYLLAEQEVDRSLFDRQIDLIMTEFG
                     PVAQKFLKHVAQVNGLEKMTFADWKLDIDNDLNPEVSIDGAYDLVMKSLAPLGQEYTK
                     EIERYQTERWVDFAANANKDSGGYAADPYKVHPYVLMSWTGRMSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNTHMSTYYVEAPSTFNELMLSDYLEHQFDDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGGTFGADQLNAMMKEVLTDFWGDAVDIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVMSTAGYLNLKNNPDGAKEWLDFLKSGGSRTPLDTAMLIG
                     ADIATEKPLRDTIQFLSDTVDQIINYTEEMSHA"
     gene            2703..3182
                     /locus_tag="ACF4ZO_001466"
     CDS             2703..3182
                     /locus_tag="ACF4ZO_001466"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004602 - glutathione peroxidase activity
                     [Evidence IEA];
                     GO_function: GO:0043295 - glutathione binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HFD5486989.1"
                     /translation="MPNLYDFTVKAQNGNDLSLAAYKEKVVLIVNTATKCGLTPQYQA
                     LQALYDTYHDKGFEVLDFPCNQFLNQAPGDAEEINHFCSLTYHTTFPRFAKIKVNGKD
                     ADPLFTWLKEEKSGPLGKRIEWNFTKFLIDQNGQVIKRYSSKTDPKLIEEDLKALLG"
     gene            complement(3228..3611)
                     /locus_tag="ACF4ZO_001467"
     CDS             complement(3228..3611)
                     /locus_tag="ACF4ZO_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HFD5486990.1"
                     /translation="MNKRFKTGFLALVAMLLVACSQGTKQTQTPSVPKADHHVRLVVK
                     EDTNTIDEKVSFGKGDTVLEILKDNYEVKEKDGFITAIDGIEQDTKANKYWLFKVNGK
                     MADKGADQITVKDGDSIEFYQEVFK"
     gene            complement(3595..4098)
                     /locus_tag="ACF4ZO_001468"
     CDS             complement(3595..4098)
                     /locus_tag="ACF4ZO_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HFD5486991.1"
                     /translation="MSAKLMSRIAIMSALCVVLRMVFSSLPNVQPVTAFLLSYLLYFG
                     LAEAVLVMMLCLFLSAFLLGFGPWVFWQVTCFVLVLLLWRFVLYPLSQQFPKYQLGYQ
                     AFLAALCGLLYGVLIDTCFAYLYSMPWWSYVLAGMPFNIAHALSTLVFFPVVMMLFRR
                     LIGEQKI"
     gene            4423..5271
                     /locus_tag="ACF4ZO_001469"
     CDS             4423..5271
                     /locus_tag="ACF4ZO_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HFD5486992.1"
                     /translation="MRRKIKPIVVLVFFILLAMVLIIGKRQANHAKQKEVEDAKSHIP
                     IATSNPSKAKTSTSETEDFILNPIVDVSGWQLPEEIDYDTLSRHISGAIVRVYGGSQI
                     TAHNNAAFTTGIDKSFKTHIKEFQKRNVPVAVYSYALGRSTKEMKEEARAFYKNAAPY
                     NPTYYWIDVEEATMKDMNKGVTAFREELKKLGAENVGLYIGTYFMAEQDISTKGFDAV
                     WIPTYGSDSGYYEAAPNTTLDYDLHQYTSQGYLSGFNNALDLNQIAVTKDTKKTFEKL
                     FGNSNN"
     regulatory      5399..5495
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            5540..6103
                     /gene="thiT"
                     /locus_tag="ACF4ZO_001470"
     CDS             5540..6103
                     /gene="thiT"
                     /locus_tag="ACF4ZO_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015234 - thiamine transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015888 - thiamine transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HFD5486993.1"
                     /translation="MSPNTNVKYLIEAAIFAALAMALSFIPDFAGWFSPSYGAIALVI
                     FSLRRGLKYGMLAGLIWGLLHFVLGKVYYLSMSQVFIEYILAFTSMGLAGSFSDSLIK
                     TLRRQQTFFAVFLAIMASLLAVTVRYLWHFLAGIIFWGSYAPKGMSAIWYSFSVNGTA
                     GVLTFLITCLALMIALPIHPQLFDPKD"
     gene            6194..6673
                     /locus_tag="ACF4ZO_001471"
     CDS             6194..6673
                     /locus_tag="ACF4ZO_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HFD5486994.1"
                     /translation="MAKKTKLKKTLVEQILDKANIAHQGLKLNALEGDFPDDLQPSDI
                     YKTLALTGDQTGPLIGIIPLTEHLSEKQLAKVSGNKKVSMVPQKDLQKTTGYIHGANN
                     PVGIRQKHSYPIFIDQTALEKGQIIVSAGEVGRSIKISSQALADFVGASFADLKKRK"
     gene            7013..7636
                     /locus_tag="ACF4ZO_001472"
     CDS             7013..7636
                     /locus_tag="ACF4ZO_001472"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HFD5486995.1"
                     /translation="MKLYFVRHGKTLWNLEGRFQGAGGDSPLLEEAKDEIHLLGKELA
                     KVAFDAVYTSDLQRAMATAAIILDAFDQQPKLYHTDQLREWRLGKLEGAKITTMAAIY
                     PQQMLAFRENLAQFKPDQFEAESIYQTTQRVCHLIQSFKDKHYQNVLIVGHGANLTAT
                     IRSLLGFEPALLLAKGGLDNASLTILETKDYLTYDCLIWNDKSFLEV"
     gene            complement(7745..8647)
                     /locus_tag="ACF4ZO_001473"
     CDS             complement(7745..8647)
                     /locus_tag="ACF4ZO_001473"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000633099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFD5486996.1"
                     /translation="MITAIVFDVDDTIYDQQAPYRIAMEKCFPDFDMSVMNQAYIRFR
                     HYSDVGFPRVMAGEWTTEYFRFWRCKETLLEFGYREIDEAAGVHFQEVYEHELENITM
                     LDEMRMTLDFLKSKNVPMGIITNGPTEHQLKKVRKLGLYDYIDPKRVIVSQATGFQKP
                     EKEIFNLAAEQFDMNPQTTLYVGDSYDNDIMGAFNGGWHSMWFNHRDRQLKPGTKPVY
                     DVAIDNFEQLFGAVKVLFDLPDNKFIFDINDKKNPILQMGINNGLMMAAERLLESNMS
                     IDKVVILLRLTKQQEKVLRLKYAR"
     gene            8821..10314
                     /gene="lysS"
                     /locus_tag="ACF4ZO_001474"
     CDS             8821..10314
                     /gene="lysS"
                     /locus_tag="ACF4ZO_001474"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004824 - lysine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006430 - lysyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HFD5486997.1"
                     /translation="MSNQHIEELNDQQIVRREKMMALAEQGIDPFGKRFDRTANSAEL
                     KEKYADKTKEELHELNETAIVAGRLMTKRGKGKVGFAHLQDREGQIQLYVRKDSVSED
                     NYEIFKKADLGDFIGVEGEVMRTDMGELSIKATKLTHLSKSLRPLPEKFHGLTDIETI
                     YRKRHLDLISNRESFDRFVTRSKMISEIRRYLDGLDFLEVETPVLHNEAGGAAARPFV
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADYLDIMNLTEGIIQHAAKAVKGDGPIDYQGTEIRINEPFKRVHMVDAIKEVTGVD
                     FWPEMTVEEAIALAKEKQVPLEKHFTSVGHIINAFFEEFVEETLVQPTFVFGHPVEVS
                     PLAKKNPEDTRFTDRFELFIMTKEYANAFTELNDPIDQLSRFEAQAQAKELGDDEATG
                     IDYDFVEALEYGMPPTGGLGIGIDRLCMLLTNTTTIRDVLLFPTMKP"
     gene            10450..10590
                     /locus_tag="ACF4ZO_001475"
     CDS             10450..10590
                     /locus_tag="ACF4ZO_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5486998.1"
                     /translation="MTKEYISYISAAIFLLYGLLAAKWIFLGLGLILVLVGLADRLNS
                     KK"
     gene            complement(10687..10899)
                     /locus_tag="ACF4ZO_001476"
     CDS             complement(10687..10899)
                     /locus_tag="ACF4ZO_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PC4/YdbC family ssDNA-binding protein"
                     /protein_id="HFD5486999.1"
                     /translation="MAEFTFNIEEHLLTLSENDKGWTKELNRVSFNGAEAKWDIRTWS
                     PDHTKMGKGITLTNEEFKTILDAFRK"
     gene            complement(11109..12395)
                     /locus_tag="ACF4ZO_001477"
     CDS             complement(11109..12395)
                     /locus_tag="ACF4ZO_001477"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:1901576 - obsolete organic substance
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HFD5487000.1"
                     /translation="MSHMKKRPEVLSPAGTLEKLKVAIDYGADAVFVGGQAYGLRSRA
                     GNFSMEELQEGIDYAHARGAKVYVAANMVTHEGNEIGAGEWFRQLRDMGLDAVIVSDP
                     ALIVICSTEAPGLEIHLSTQASSTNYETFEFWKAMGLTRVVLAREVNMAELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCVLSNHMSHRDANRGGCSQSCRWKYDLYDMPFGGERRSL
                     KGEIPEDYSMSSVDMCMIDHIPDLIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     MESPEAFYAIKEELIDELWKVAQRELATGFYYGIPTENEQLFGARRKIPQYKFVGEVV
                     AFDSASMTATIRQRNVIMEGDRIECYGPGFRHFETVVKDLHDADGQKIDRAPNPMELL
                     TISLPREVKPGDMIRACKEGLVNLYQKDGTSKTVRT"
     gene            complement(12497..13423)
                     /locus_tag="ACF4ZO_001478"
     CDS             complement(12497..13423)
                     /locus_tag="ACF4ZO_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase U32 family protein"
                     /protein_id="HFD5487001.1"
                     /translation="MEKIIITATAESIEQVKALLAAGVDRIYVGEANYGLRLPHNFSY
                     DELRQIAKLVHDAGKELTVACNALMHQDMMDQIKPFLDLMIEIAVDYLVVGDAGVFYV
                     NKRDGYNFKLIYDTSVFVTSSRQVNFWGQHGAVESVLAREIPSAELFTLAENLEFPAE
                     VLVYGASVIHHSKRPLLENYYHFTKIDDEVSRERGLFLAEPGDASSHYSIYEDNHGTH
                     IFINNDIDMMSKLGELYAHGLTHWKLDGIYCAGDDFVAITKLFIQAKTLLEAGQFTQE
                     EAEKLDQAVHAHHPAGRGLDTGFYEFDPKTVK"
     gene            13622..13906
                     /locus_tag="ACF4ZO_001479"
     CDS             13622..13906
                     /locus_tag="ACF4ZO_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HFD5487002.1"
                     /translation="MPAPLKKHNSVEQDDSYQESQSKFRDFQEFNGQSAKLKELVFFA
                     RIASFSLITVLFAFVLLVMNLAPMFAFLFASIISLGITSLLAKVIKSLLM"
     gene            complement(14065..14493)
                     /locus_tag="ACF4ZO_001480"
     CDS             complement(14065..14493)
                     /locus_tag="ACF4ZO_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HFD5487003.1"
                     /translation="MNKSFKNLVIGAVSGVAAAYFLSTEKGKALKNRAEKAYQAYKES
                     PDDYHQFAKEKGSEYSHLARDTFYDVKDKLASGDLTKEDMLDLLKDKTTAFVQKTKET
                     FAEVEAKEKQDDVIIDLNEDDIIIDYTEQDEPVSDTLDKH"
     gene            complement(14486..14893)
                     /locus_tag="ACF4ZO_001481"
     CDS             complement(14486..14893)
                     /locus_tag="ACF4ZO_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HFD5487004.1"
                     /translation="MDLVGISLMIIALAFVALVIFLIIVLKKVSETIDEAKKTISVLT
                     SDVNVTLHQTNDILAKANILVEDVNGKVATIDPLFVAIADLSESLSDLNSQARHFGQK
                     ATNATGNVSKAGKLALVGKVASKVFGKKGEKHE"
     gene            complement(14915..15694)
                     /gene="lgt"
                     /locus_tag="ACF4ZO_001482"
     CDS             complement(14915..15694)
                     /gene="lgt"
                     /locus_tag="ACF4ZO_001482"
                     /EC_number="2.5.1.145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008961 -
                     phosphatidylglycerol-prolipoprotein diacylglyceryl
                     transferase activity [Evidence IEA];
                     GO_process: GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HFD5487005.1"
                     /translation="MINPIALKCGPLAIHWYALCILSGLVLAVYLASKEAPKKGISSD
                     AIFDFILIAFPLAIVGARIYYVIFEWSYYVKHLDEIIAIWNGGIAIYGGLITGALVLL
                     AYCYNKVLNPIHFLDIAAPSVMVAQAIGRWGNFINQEAYGKAVSQLNYLPSFIQKQMF
                     IEGSYRIPTFLYESLWNLLGFVIIMMWRRKPKSLLDGEIFAFYLIWYGSGRLVIEGMR
                     TDSLMFLGIRISQYVSALLIIIGLIFVIKRRRQKGISYYQE"
     gene            complement(15691..16623)
                     /gene="hprK"
                     /locus_tag="ACF4ZO_001483"
     CDS             complement(15691..16623)
                     /gene="hprK"
                     /locus_tag="ACF4ZO_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006109 - regulation of carbohydrate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HPr(Ser) kinase/phosphatase"
                     /protein_id="HFD5487006.1"
                     /translation="MTVTVKMLVQKVKLDVVYATDNLLSKEITTSDISRPGLEMTGYF
                     DYYAPERLQLFGMKEWSYLTQMTSHNRYSVLKEMFKKDTPAVVVSRNLAIPKEMVQAA
                     KEEGISLLSSRVSTSRLAGEMSYFLDASLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDVYAKDEETLWGEPAEILRHLLEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAIYLENFEAGKVFDRLGNGNEEITFSGVRIPRIRIPVKTGRNVSVVIE
                     AAAMNHRAKEMGFDATKTFEDRLTQLITKNEVSQ"
     gene            complement(16988..17260)
                     /locus_tag="ACF4ZO_001484"
     CDS             complement(16988..17260)
                     /locus_tag="ACF4ZO_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HFD5487007.1"
                     /translation="METKFYKQRKNRLVAGVIAGLADKYGWDLALARVLAALLIYGTG
                     FGVLLYILLAIFLPYKEDLLEERYGRGPRRRKDADVLNEEEDGWFW"
     gene            complement(17324..17761)
                     /locus_tag="ACF4ZO_001485"
     CDS             complement(17324..17761)
                     /locus_tag="ACF4ZO_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HFD5487008.1"
                     /translation="MTLTNYVQEVSLADFGKPFHHKAYWNKRLKTTGGRFFPKDGHLD
                     FNPRMLEENGELIFRKIVRHELCHYHLYFEGRGYHHKDRDFKDLLAQVNGLRYVPTSS
                     KSKTNHHYSCQTCGQVYQRKRRINLAKYVCGNCHGKLIEKNQS"
     gene            complement(17748..>18144)
                     /locus_tag="ACF4ZO_001486"
     CDS             complement(17748..>18144)
                     /locus_tag="ACF4ZO_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HFD5487009.1"
                     /translation="LAAVQVPQMAETLAIGQETLKDIIADLLKPGRDLRDDFEAPILR
                     QDILDLKDLEIGQKLEGTVRNVVDFGAFVDIGVHEDGLIHISEMSKTFVNHPSQVVSV
                     GDLVTVWVSKIDLDRHKVNLSLLPPRDTH"
BASE COUNT         5570 a         3772 c         3196 g         5606 t
ORIGIN      
        1 ttgggattgt ctaactctag accgtgtttt tgggctaagt ttttgtactc tgttgtcaac
       61 ttggtcactg cttgaatgag agaaccatcg taatactgca tgacattttt tatctcgttt
      121 ttcacctgaa gctttttctc gcgaataata tctgtctgca tgatcatttc aatataacga
      181 tatagctcct gacgccattt ctcaagacta atcacaccag ccttagcatc acggtatttg
      241 cgcagaagtt tatgaatgtg agttgtcaat tccagaatcg ttttacgttg tacttgcgtc
      301 ggatgtgctg ttaaaacagg aaccacatta acctgctcca aaatgtcttt accattatct
      361 tttccagcaa gatccttgat ggttagggct aattttccta aataatcagt atccgtatta
      421 ttttgataat taatttcata ggctaaatcg acatcttctg aaatattgat tagcaagggt
      481 aaaatagaaa aatacctgga aatcacttcc atttcttgat ttgaaatatt ggcgacaact
      541 ttttctaatt ctatgtaatc ttgtttttca gataacacca taatagactc gataactgta
      601 aacgcgtcat ctccaatcat ccgtcgtgtg atattttcca acatttcttt caaaagagca
      661 acttcttcag caatgatagc ttgattgtta ctactctcta actttttaag tggcaaatga
      721 ccatctcctt ctttgctagt ttcttctatc ataccacttt ttaccaaaaa taaaagtgat
      781 catgttcata acgtttgttt tttaacaaaa gtaagcgcct tatttcaaag aatgtttgga
      841 taggtttagt ctccatattc cactaaaatt ctgttatact agtcttgact atattgttaa
      901 ggagacaact atggaattga aaaaacgttc agaattccct gaaaatgaac tttgggatct
      961 aacagcgctc tacaaagacc gccaagattt tttactcgct attgaaaaag ccttacaaga
     1021 tattgacctg tttaagcgca attatgaagg ccgcttaaca tcggtggacg atttcactca
     1081 ggccttaata gaaattgagc atatttatat tcaaatgagt catattggca cttatgcctt
     1141 tatgcctcaa accactgact tttcagatga aagttttgct caaattgctc aggctggcga
     1201 tgatttcatg actaaagcta acgttgccct tagcttcttt gacaccgcct tagccaatgc
     1261 cgaccttgac gtgctagata cattagaaaa gaacccttat ttcagcgcag ctattcgcat
     1321 ggcaaaaatc caaaaggaac acctcttaag tcctgatgta gaaaaagctt tggctaactt
     1381 acgcgaggtt atcaatgcgc cctatgatat ttacaccaaa atgcgggcta gtgactttga
     1441 catggatgat tttgaggtgg atggtaaaac ctataaaaat agctttgttt cttacgaaaa
     1501 tttctatcaa aatcacgaaa atgctgagat tcgtgaaaaa gccttccgct ctttttcaaa
     1561 cggtctccgt aaacaccaaa atacagctgc agcggcttac ttagccaagg ttaaatctga
     1621 aaaactgtta gcggatatga aaggctacgc ttctgtcttt gattacctcc tagctgaaca
     1681 ggaagtggat cgtagcttat tcgaccgcca aattgacctc atcatgactg aatttggacc
     1741 ggttgctcag aaattcttaa aacatgtcgc ccaagtcaat ggtcttgaga aaatgacttt
     1801 tgctgactgg aaactagata ttgacaatga tctcaatcca gaagtcagca ttgatggcgc
     1861 ttatgacctc gtgatgaaat ctctagcccc attagggcaa gaatacacga aagaaatcga
     1921 acgttaccaa actgaacgct gggttgactt tgctgctaac gccaataagg attctggtgg
     1981 ttatgccgct gatccctaca aggttcatcc gtatgtctta atgagttgga ctggaagaat
     2041 gtctgatgtt tataccctta ttcatgaaat cggtcactct ggtcaattca ttttttcaga
     2101 taatcaccaa agttacttca acacccatat gtcaacttat tacgtcgaag cgccatcgac
     2161 ctttaatgaa ttgatgctta gtgattactt ggaacatcag tttgatgacc ctcgtcaaaa
     2221 acgttttgct cttgctcacc gtttaacaga cacctacttt cataacttca tcactcacct
     2281 attggaagcg gctttccaac gtaaggttta caccctgatt gaagaaggcg gtacctttgg
     2341 agctgaccaa ttaaatgcaa tgatgaaaga ggtcttaaca gacttctggg gagatgccgt
     2401 tgacattgac gatgacgcag ctcttacctg gatgcgccaa gcgcattact acatgggctt
     2461 atatagttat acctattctg ctgggcttgt tatgtcaaca gctggttacc ttaaccttaa
     2521 aaacaaccca gatggggcaa aagaatggct tgatttccta aaatcaggtg gcagccgtac
     2581 gcctcttgat actgcaatgc tcattggggc agacattgcc actgaaaagc ctcttcgaga
     2641 taccattcaa ttcttgagtg ataccgttga ccaaattatt aattacaccg aggagatgtc
     2701 acatgcctaa tctctatgat tttacggtta aggctcaaaa cgggaatgac ctttccttag
     2761 ctgcttataa agaaaaggtt gttttgattg ttaatacagc taccaagtgt ggattaaccc
     2821 cacaatacca ggccttgcaa gcactatatg acacatacca tgacaaggga tttgaggtct
     2881 tagattttcc ttgcaaccaa tttttaaatc aagctccagg agatgctgag gagattaatc
     2941 acttttgcag tctgacctat cacactactt tccctcgctt tgctaaaatc aaagtgaatg
     3001 gtaaagacgc tgatcctttg ttcacctggt taaaagaaga aaaaagtggt ccccttggga
     3061 aacgcatcga atggaatttc actaaatttc tcattgacca aaatggtcaa gtcattaaac
     3121 gctattcctc aaagacagat cctaaactaa ttgaagaaga ccttaaagca cttcttggtt
     3181 aatacaaaat agacttggcg tgccaagtct attttgtatt atagttacta tttaaaaact
     3241 tcttgataaa attcaatgct atcaccatct ttaacggtga tttgatcggc acccttatct
     3301 gccatctttc cattcacctt aaaaagccag tatttgttag ctttcgtgtc ttgctcaata
     3361 ccatcaatag cagtgataaa gccatctttt tctttgacct cataattatc tttgagaatc
     3421 tcaagcaccg tatctccttt tccaaaagaa actttttcat caatggtatt ggtatcttct
     3481 ttgacaacta agcgaacgtg atggtctgct tttggaacgc ttggagtctg tgtttgtttt
     3541 gttccttgcg agcaagcaac aagtagcata gcaacaagcg ctagaaatcc tgttttaaat
     3601 cttttgttca ccgattaacc tcctaaataa catcatcaca actggaaaaa agacgagagt
     3661 tgataaagca tgcgctatat taaagggcat cccagctaga acatagctcc accaaggcat
     3721 actatacaaa tacgcaaaac aagtatctat caacacccca taaaggaggc cacataaggc
     3781 ggccaagaaa gcctgataac caagctgata tttggggaat tgctgagaca gagggtacaa
     3841 gacaaaacgc cataataaaa gaacaagcac aaaacaagta acttgccaaa agacccaagg
     3901 gccaaatccc agcaaaaagg ctgataaaaa taagcacaac atcataacta atacagcctc
     3961 ggctaaccca aagtaaagaa gataactgag taaaaatgcc gtcacaggct gcacgttagg
     4021 caggctgcta aaaaccattc tcaacacaac acatagggct gacatgatag caatgcgact
     4081 cataagctta gctgacataa acttcttcct cgtttttttc tctattatga cagatttaca
     4141 gagcgtttac cagtttggag ctcacttatt tatcaaatga taataacatg agaattaaat
     4201 aacaaaacag tacttgctga ctgtcatgat atagtcaaag actaaactaa tattgtaaag
     4261 aatatagcta ccaactataa gagatagtga cataaacttg acatagttag agaggatctc
     4321 atttgtaact tctaaaagat aataccttaa aatgcaagac aatataagaa aacagttagg
     4381 atattttgat tttttttagt aattagggta caataacagt taatgagaag aaaaataaaa
     4441 cctattgttg tgctagtctt ctttatttta ctggcaatgg tattgattat cggaaaaaga
     4501 caagctaatc atgcgaaaca aaaagaagtt gaagacgcta agagtcatat tcctattgca
     4561 accagtaatc ctagtaaagc aaaaactagc acttctgaaa ccgaagactt tattttaaat
     4621 cctattgttg atgtttccgg ctggcaactc cctgaagaaa ttgattatga cacattgtcg
     4681 cgtcacatct ctggcgcaat tgtacgtgtc tatggaggat cgcaaattac agctcataac
     4741 aacgctgctt ttacaactgg aattgacaaa tcttttaaaa cgcatatcaa agaatttcaa
     4801 aaacgaaatg ttcctgtagc tgtttacagt tacgcacttg gtcgtagtac taaagagatg
     4861 aaagaagagg cccgagcttt ctacaaaaac gctgctccct ataatccaac ttactactgg
     4921 attgatgtcg aagaagccac tatgaaagat atgaataaag gcgtaacagc cttccgagaa
     4981 gagcttaaaa aacttggtgc tgaaaatgtt ggtctctata ttggaactta ttttatggca
     5041 gaacaagata tttcaacaaa aggtttcgat gctgtatgga ttccgactta tggtagtgat
     5101 tctggctatt atgaggctgc tcctaataca accttagatt acgatttaca ccaatatacc
     5161 tcacaaggtt atctcagtgg ttttaacaat gctttagatt taaatcaaat tgccgtaaca
     5221 aaagacacta aaaaaacgtt tgagaagtta tttggcaact ccaacaatta agaggttagc
     5281 atcatggcta atcttttttt atagtttaca tcttaccaag aaaaactcta ggtcaataat
     5341 ttaaaacccc ttatccttga caaggagatt atctcatcat ataatgaaag cactataata
     5401 tttcacaaag gagtgctttg gctgagatcg caattgcgaa atcctgagga cctgatcttg
     5461 ttagtacaag cgtagggatt gtgaccaata atcaatgatt ggaaagcgat actctttttg
     5521 tgcacaaaag gagtttttta tgtcaccaaa caccaatgtc aaatacctta tcgaagctgc
     5581 tatttttgct gcattggcga tggccctttc atttattcca gattttgctg gctggtttag
     5641 tccttcttat ggtgctattg cactggttat tttctctttg cgccgtgggt taaagtacgg
     5701 catgttggcg ggtctcattt gggggctact tcactttgta cttggaaaag tttactatct
     5761 cagcatgtcc caagtcttta ttgaatatat cttagccttt acctctatgg gattagccgg
     5821 tagtttctct gatagtttga ttaaaacttt aagaagacaa caaacctttt ttgccgtttt
     5881 tcttgcaata atggctagtt tactagccgt tacagtacgt tacttgtggc acttccttgc
     5941 aggaatcatt ttctggggca gttacgcccc taaaggcatg tccgctatct ggtattcttt
     6001 tagcgttaat ggtacagctg gtgtcctaac ttttttaata acatgtttag cgttaatgat
     6061 tgctttacca attcatcctc aattatttga tcccaaagac taatttttag tcatttgaat
     6121 cttacattaa aaaaatggta taataatgtt gttataccat ttttttatgt ttagataaag
     6181 gtaaggactt gatatggcta aaaaaacaaa actcaaaaaa accttagtag aacaaatcct
     6241 cgataaggct aatattgctc atcaaggact caagcttaat gctttagaag gcgactttcc
     6301 agatgatctc caaccatcag atatttacaa gacacttgct ctgactggtg atcaaacagg
     6361 tcctctaatt ggcattattc cattaacaga acacttatca gaaaaacaat tggcaaaagt
     6421 atcaggtaac aaaaaagtgt ccatggttcc tcaaaaagac ttgcaaaaga caacaggcta
     6481 tattcacggt gccaataatc ctgttggaat tcgtcaaaaa cattcatatc ctatttttat
     6541 tgaccaaact gcactggaaa aaggtcaaat aatcgtttca gctggtgaag ttgggcgttc
     6601 tataaagatt tctagccagg ctctagctga tttcgttggc gcaagctttg ctgatttaaa
     6661 gaagagaaaa tgaacactat tgccaacttt atctggtttc ttttttaagt tttcgccttg
     6721 attaagctag tctttgttta gtattatttt gatctcaact gctttaacat tgatcctgtt
     6781 aatctttttc ttttgtaaag gcttgatatc acgacaaatt caggtcgatt tgtcttaaat
     6841 ctaatatggg ctttacactt taatcagaac ctagctatta tacacttata ctacgctttt
     6901 ttactttatc ttttcactat aggtattatt tttgcttggt gatgcctaaa ctttttctgg
     6961 ttactttttt atttttagcg ctcgcatcag ttatctctaa aaggaggctt aaatgaaatt
     7021 atattttgta agacatggga aaaccctttg gaatttagaa ggtcgctttc aaggcgctgg
     7081 gggcgattcg ccattacttg aagaggcaaa agacgaaatt cacttacttg gcaaagagtt
     7141 agctaaggtg gcttttgatg ccgtttatac tagcgacctt caaagagcta tggcaacagc
     7201 agctattatc ttagatgctt ttgaccaaca gccaaaactt taccacaccg accagcttcg
     7261 ggagtggaga ttaggtaaac tggaaggggc taaaataaca acaatggcag ctatatatcc
     7321 ccaacaaatg ctggcttttc gggagaatct agcccagttc aaaccagatc agttcgaggc
     7381 tgaatcaatt taccaaacga ctcaacgtgt ctgccatctt atccaatcgt ttaaagataa
     7441 acattatcaa aacgttctta ttgtaggaca cggcgctaac ttaacagcaa ctattcgctc
     7501 attattaggt tttgaacctg ctcttttact cgctaaaggt ggcttagata atgccagtct
     7561 tactattctt gaaactaaag attatttaac ttatgactgt ttaatttgga atgataaatc
     7621 ttttctagag gtgtaaaacc actagacaat aataaaaaaa gctaacacat tgatttctta
     7681 ctgacaagac actcactttg ctagcttttt tttattatta tctaatgggc tattatggtt
     7741 tcatctatct ggcatatttt aaacgtagca ctttttcttg ctgcttggtt aatcgaagca
     7801 agataaccac cttgtcaatg ctcatgttac tttcaagtaa acgctctgct gccatcatca
     7861 agccattatt gattcccatc tgtaaaatcg gatttttctt gtcattaata tcaaaaataa
     7921 atttattatc aggtaaatca aagagtactt taacggcacc aaagagctgt tcaaagttat
     7981 caatagccac atcataaaca ggcttagttc ctggttttag ctgacgatct ctatgattaa
     8041 accacataga atgccaacca ccattaaagg cacccatgat atcattgtca taagagtccc
     8101 caacatatag tgtggtttgt gggttcatgt caaattgttc tgctgccagg ttaaaaattt
     8161 ctttttctgg tttttgaaag cctgttgctt ggctcacaat gacacgctta gggtcaatat
     8221 aatcataaag ccctaattta cgaacttttt tcagctgatg ttctgttggc ccattggtaa
     8281 taatccccat aggaacattc tttgatttta aaaagtcaag ggtcatgcgc atctcatcta
     8341 acatggtaat gttctcaagt tcgtgctcat agacttcttg aaaatgtact cccgcagctt
     8401 cgtcgatttc tcgatagcca aactcaagca gtgtttcctt gcaacgccag aatcggaaat
     8461 attctgtggt ccactcccct gccattactc ttgggaatcc aacatctgaa tagtgacgaa
     8521 agcgaatata agcttgattc attactgaca tatcaaaatc tgggaagcac ttttccatgg
     8581 cgattcgata aggcgcttgc tggtcgtaaa ttgtgtcatc cacatcaaaa acaatagcag
     8641 taatcatgag tctcttttct tttctagttt aatatcccaa tcattatact attttccatt
     8701 aggcttttca attttatttt caaaaaagtg ccccgctgca gtcgcatttt ccaacgaaat
     8761 ataggtgtat tctagtctct tttatgatac aatggaaagg aaatcgtatt ggaggaaaat
     8821 atgtctaatc aacacatcga agaattaaat gaccaacaga ttgtccgtcg tgaaaagatg
     8881 atggctctgg ctgaacaagg aattgatcct ttcggtaaac gctttgaccg cacagccaat
     8941 tctgctgaat taaaagaaaa gtatgctgat aaaacaaaag aagaattaca tgagttaaac
     9001 gaaacagcta ttgttgctgg ccgcttgatg acaaaacgtg gcaaaggtaa ggttggtttt
     9061 gctcatcttc aagaccgtga aggccaaatc caactttatg ttcgcaagga ctctgttagc
     9121 gaagacaact atgaaatctt caaaaaagcc gatttaggcg actttatcgg cgttgaaggc
     9181 gaagtcatgc gtacagacat gggcgagttg tcaatcaagg caaccaagtt gactcacctt
     9241 tctaaatcac ttcgtcctct tcctgaaaaa ttccacggat taactgatat tgaaaccatt
     9301 taccgtaagc gtcaccttga tttaatttca aatcgtgaaa gctttgaccg cttcgtgacc
     9361 cgttccaaaa tgatttcaga aatccgtcgt tatttagacg gtcttgattt cctagaagta
     9421 gaaacgcctg tgcttcataa cgaggctggt ggtgctgctg ctcgtccttt cgttactcac
     9481 cataatgctc aaaacattga tatggtgctt cgtatcgcaa cagaacttca tttgaaacgt
     9541 ttgattgttg gtggtatgga acgtgtctat gaaattggtc gtatcttccg taacgaggga
     9601 atggatgcta ctcataatcc tgagttcact tctattgagg tttaccaagc ctatgcagac
     9661 tatcttgata tcatgaacct gacagaaggc attatccaac atgctgctaa agctgttaaa
     9721 ggtgatggcc ctattgatta tcaaggaact gaaatccgta tcaatgaacc tttcaaacgt
     9781 gttcacatgg tagatgctat caaggaagtg acaggtgttg atttctggcc tgaaatgact
     9841 gtcgaagaag ctattgcact tgccaaagaa aaacaggtcc cactcgaaaa acacttcaca
     9901 agtgtcggac atatcatcaa tgctttcttc gaagaattcg ttgaagaaac cttggtccaa
     9961 ccaacctttg tgtttggtca tcctgttgaa gtatcgcctt tggctaagaa gaatccagaa
    10021 gatacccgct tcaccgaccg cttcgaactt ttcatcatga ccaaagaata cgccaatgct
    10081 ttcacagagt tgaatgatcc cattgaccaa ttatctcgtt ttgaagcaca agcacaagct
    10141 aaagaacttg gtgatgacga agcaactggc attgactacg acttcgttga agctcttgaa
    10201 tatggtatgc cgccaaccgg tggactcgga atcgggattg atcgtctttg catgttatta
    10261 acaaacacaa caacaatcag agatgtgctt ttattcccaa cgatgaaacc ttaacttttt
    10321 taagatttgt attcatatct taaaaccgat aagtggcaat ataacataac gttttattat
    10381 ctctaaccag tcttcattac catgaagact ggtttattaa cagtagctta tagaaagtga
    10441 cttaacaaga tgaccaaaga atatatctcc tacattagtg ctgctatctt cttgctttat
    10501 ggccttttag ctgccaaatg gatttttctt gggctaggct taattttggt acttgtcggc
    10561 cttgctgatc gcctcaattc aaaaaaataa tccttctatt cgcccctgtc ctcttaacct
    10621 agcgatgtca tcaccaggtt aagaggacag gggcgaacga gggattatgt ttcgattaag
    10681 gtaacattac ttacgaaaag cgtctaagat ggttttaaat tcttcattag taagagtaat
    10741 gcctttcccc attttcgtat ggtctggact ccacgtgcgg atatcccatt tcgcttctgc
    10801 gccattaaag ctgacgcggt tcaattcttt cgtccaacct ttatcatttt ctgataaggt
    10861 gagtaaatgt tcctcaatgt tgaatgtaaa ttctgccatt agttttcctc ctcatctata
    10921 ctattcgaaa ttaaagtgga aaaaatcatc tttttttcac tttttttatg actcattctc
    10981 ctattattct atcaagtttt gagaaaataa gctattgtga tatccaactt tcaaaaaaaa
    11041 caggctctct tttcccaact atggtcgtat accatttgga aaaagagggc ctctagtatt
    11101 tcttgttatt atgttctaac agttttactg gtgccatctt tttgatagag gttgacaaga
    11161 ccttccttgc aagccctaat catatcccct ggcttaactt ctctcggtaa agagatggtt
    11221 aagagttcca ttggatttgg ggcacggtca atcttttggc catccgcatc atgtaagtcc
    11281 ttaacaactg tttcaaaatg acggaaacct ggtccataac attcaatccg atcgccttcc
    11341 atgatgacat tacgctgacg aatggtcgct gtcatgctag ctgagtcaaa ggcaactact
    11401 tctccgacaa atttatattg tggaattttg cggcgagcac caaataattg ttcattttca
    11461 gttgggatac catagtaaaa acctgtagcc aactcgcgct gggcaacctt ccacaactcg
    11521 tcaatcaatt cctctttgat agcataaaaa gcttctgggc tttccatgta agcatctaca
    11581 gccgccttgt aacagttggt tacggttgag acgtagtgga tagatttcat tcggccttca
    11641 atttttaagc tatcaacccc attttcaatc aggtcaggaa tatggtcaat catacacatg
    11701 tcaacagagg acatagaata gtcttctgga atttcccctt ttaaggagcg gcgctctcct
    11761 ccaaatggca tgtcatacaa atcatacttc cagcggcaag actgtgagca gccgcccctg
    11821 ttggcatcac ggtgactcat gtggtttgac aaaacacagc ggcctgaata agaaatacac
    11881 atggctccat ggacaaaggc ttcaatttcc acatctgtcc gcttacggat ttctgctaat
    11941 tcagccatat taacctcgcg agctaaaaca actcgggtca aacccatggc tttccaaaat
    12001 tcaaaggtct cgtaattggt agatgaagct tgcgttgaca aatgaatttc caaacctggg
    12061 gcttctgttg aacaaataac aatcaaggct ggatctgaaa caatgaccgc atcaagcccc
    12121 atatcacgca gttgacgaaa ccactcgccc gcaccaattt cgttcccttc gtgggtaacc
    12181 atgttagcag caacatagac cttagctcca cgcgcatgtg cataatcaat gccttcttgc
    12241 aattcttcca tagagaagtt accagcgcgg cttcttaggc cataggcctg ccctccaaca
    12301 aaaacagcat ctgcgccata gtcaatcgca acttttaatt tttcaagtgt tccagcaggt
    12361 gataagacct cgggacgttt tttcatatgt gacatgtgat attctttcta ttttcaagat
    12421 aggtagatta cctgtgtaat ggtgtcataa ccctgtcttg ccctgaaata gtaaactcac
    12481 tcaagacaag gattacttat ttaacggttt ttggatcgaa ctcataaaag ccagtatcta
    12541 atccacggcc agctggatga tgggcatgca ctgcttgatc aagcttttca gcttcttctt
    12601 gggtaaattg cccagcttct aataaggttt tagcctgaat aaacaattta gtaatagcga
    12661 caaaatcatc acctgcacag taaatgccat ctagcttcca atgagttaag ccatgcgcat
    12721 acagctcacc caatttagac atcatgtcga tatcgttatt aatgaaaata tgagtgccat
    12781 gattgtcttc ataaatggag taatggctgc tagcatctcc tggttctgcc aagaaaagtc
    12841 ctcgttcacg actaacctca tcatcaatct ttgtaaaatg gtaataattt tctagcaagg
    12901 gacgtttcga gtgatgaatc accgaggcgc cgtaaactag cacctctgct ggaaattcca
    12961 aattttcagc taaggtgaat aactctgctg atgggatttc ccttgctaag acactttcaa
    13021 cagcaccatg ttgcccccag aaatttacct gacggctaga agtcacaaaa acagaggtat
    13081 cataaatcag tttaaagtta tagccatccc ttttattgac ataaaacaca cctgcatcac
    13141 caaccacaag ataatcaaca gcaatctcta tcattaagtc taaaaagggt ttgatctgat
    13201 ccatcatatc ttgatgcatc aaagcattgc aagctactgt caactctttg cctgcatcat
    13261 gcactagttt ggcaatttgt ctcaattcat cataagaaaa attatgggga agacgtaacc
    13321 cgtaattggc ttcaccaaca taaatacgat caacaccagc agctaataaa gctttgactt
    13381 gctcaatgct ttcagctgtg gctgtaataa ttattttttc catataagct ttattatacc
    13441 aaaaatttta agaccttaag catatttctt gcaaaagccc aaacgttaag ctagtcccct
    13501 tactgttata gcatgataag tcacttgtca ttagtaaatc ttttcaaatc ttttaaaaaa
    13561 agatgacaag aaaagacttt tatgatagaa ttacttagta tgttaaggaa aggagaggac
    13621 tatgcctgca ccgttaaaga agcataattc ggttgaacag gatgattctt accaagaatc
    13681 tcaaagtaaa tttcgagatt ttcaagagtt caatggccaa agtgcaaagc taaaagaatt
    13741 agtcttcttt gctcgtatcg ctagtttcag ccttattacc gttttatttg catttgtcct
    13801 gctcgtaatg aatttagcgc caatgtttgc tttcttattt gcaagcatca tcagcttagg
    13861 cattacttcc ttattagcca aggttatcaa atcattactg atgtaacttc cagagtccat
    13921 tttgtatgac tctttttctt ttgccaaaaa caaaaaaaga ttgaagccac aatcccccct
    13981 tcttcagtta gcctaaaact aaccatcggg actagtgatc agatccttca atcttttctt
    14041 cttctatgtt ttaggtcgtt ttagttagtg tttgtctaat gtatcactaa caggctcatc
    14101 ttgttcagta tagtcaatga tgatgtcgtc ttcatttaaa tcaatgataa catcatcttg
    14161 cttttctttc gcttcaactt cggcaaaggt ttcttttgtt ttttgcacga aagctgttgt
    14221 tttatctttg agcaagtcta acatgtcctc tttagttaag tcaccagaag ccaacttatc
    14281 tttcacatca taaaaagtgt cacgtgctaa atggctgtat tcactacctt tttctttagc
    14341 aaattggtgg taatcatctg gactttcttt gtaggcttga taagcttttt cagcacgatt
    14401 tttcaaagcc ttgccttttt ctgttgataa gaagtaagct gccgctactc ctgaaacagc
    14461 tccaatcact aagtttttga aacttttatt catgcttttc tccttttttt ccaaatactt
    14521 ttgaggctac tttaccaact aatgctaatt ttccagcttt tgaaacatta cctgtagcat
    14581 tagttgcttt ttgcccaaaa tgccttgctt gactatttaa atctgaaaga ctttctgaca
    14641 aatcagcaat agcaacaaac aatggatcga tggttgctac tttaccatta acatcttcaa
    14701 caaggatatt agcttttgct aaaatatcat tagtttgatg aagtgtcaca ttaacatcac
    14761 ttgtcaatac agaaatcgtt tttttggctt catcaattgt ttctgagact ttctttaata
    14821 caataatcaa gaaaatcacc aaagcaacaa atgcgagtgc aataatcatc agtgagattc
    14881 caactaagtc cataagtttc tcctttttct atccttattc ttgataataa gaaattcctt
    14941 tttgacgacg tctttttata acaaagatta agccaataat aattaataag gcagacacat
    15001 attgggagat gcgaatacct aaaaacataa gactatctgt tcgcatacct tcaatgacta
    15061 gtcttccact accataccaa attaagtaaa atgcaaagat ttctccatct aatagacttt
    15121 ttggcttacg acgccacatc ataataatga caaatcccaa aagattccaa agtgattcat
    15181 agagaaaggt cggaatgcgg taacttccct ctataaacat ttgcttttga ataaagcttg
    15241 gtaagtaatt taactggctc acagctttac cataggcttc ttggttgata aaatttcccc
    15301 agcgaccgat agcttgagcg accatgacac ttggtgcggc aatatctaaa aaatgaatgg
    15361 gattgagcac cttgttataa cagtaagcca aaagtacaag agctcctgta atgagaccgc
    15421 cataaatagc aataccgcca ttccaaatgg ctatgatttc atctaaatgc ttgacataat
    15481 aagaccattc aaaaataaca tagtaaattc ttgcaccaac aatagcaagt ggaaaagcaa
    15541 tcagaataaa atcgaaaata gcgtcagatg atattccttt tttgggtgct tcttttgatg
    15601 ctaagtaaac cgccaaaaca agtcctgaca agatacatag agcataccag tggatggcta
    15661 gtggaccaca ttttaaggca atgggattga tcattgactc acctcatttt tggtgattag
    15721 ttgagttaaa cgatcttcaa aagtttttgt agcatcaaag cccatttctt tagcccgatg
    15781 attcatcgca gcggcttcaa taaccactga aacatttcga cctgttttta ccggaatacg
    15841 aatacgaggg attctcactc ctgagaaagt tatctcctca ttaccgtttc cgagacgatc
    15901 aaaaacctta ccagcctcaa agttttcaag gtaaatggcc aattgaactt gtgatgagtc
    15961 cttcacagca ctagctccat aaagcgacat cacatcaata atacctaccc cacgaatttc
    16021 aagcaagtgg cgcaagatct ctgctggctc tccccaaagg gtttcttcat ctttggcata
    16081 gacatccaca cggtcatctg caaccaaacg atgccctcgc ttaactaatt ctaaaccagt
    16141 ctcactttta ccaattccag aatccccttg gataagaacc cccataccat aaatatccat
    16201 taaaacgccg tgaacactag tacgttcagc taaagaagcg tcaagaaaat aagacatttc
    16261 tccagctaag cggctagttg aaacacggct acttaaaagt gaaatccctt cttcttttgc
    16321 agcttgaacc atttcttttg gaatggctaa atttctagag acaaccactg caggagtgtc
    16381 ctttttgaac atctctttta aaacagaata acggttgtga gaagtcatct gtgtaagata
    16441 agaccactct ttcattccaa acagctgcaa cctttctgga gcataataat caaaataacc
    16501 agtcatttca agacctggac gtgaaatatc tgatgttgtt atctcttttg acagcaagtt
    16561 atctgtagca taaaccacat caagtttaac tttttgcact agcatcttta cagtaacggt
    16621 cataatttct cctttttcaa tattataaca caaatcgacc gttagaccct tgcaaatact
    16681 cattttttca ctactaaata agaacaacga caccaaaaat ggtcttagct ctattaaaaa
    16741 ctaggtttta tcatttagag atatgagtca aaaataagac aatggcaaac aaatacttta
    16801 ctagtatcat tgagcaatta gtgcttatta tggtgtttaa aaaggtatca tcttactaag
    16861 tcaaaaagca aaaagcctca tcatagctga taagaccctt cgcttactta catatcaaaa
    16921 cattttatta tcatcagtta atcacatggt tgctcttacg tgatgaatta tcattttaac
    16981 tgattgttta ccagaaccag ccatcttctt cttcatttaa gacatcagcg tctttacgac
    17041 gacgaggacc tcggccataa cgttcttcaa gcaagtcttc cttgtaaggt aagaagatgg
    17101 ccaacaaaat ataaagcaaa actccaaaac cagttccgta aataagaaga gccgctaaga
    17161 cacgcgctag agcaagatcc caaccatact tatctgctaa accagcaatg acacctgcaa
    17221 ccaagcgatt ttttcgctgt ttatagaatt tagtttccac gtttctttac ctcctcattc
    17281 tatgatacta gtttacattg tttttcgcaa aataaaacca gtcttacgac tgattttttt
    17341 caataagttt cccgtggcaa tttccacaaa catatttagc cagattgata cgcctttttc
    17401 gttgataaac ctgcccacag gtttggcaac tataatgatg attagtcttt gatttagagc
    17461 tagttgggac ataacgaagc ccgtttactt gagctagcag atctttgaaa tccctatctt
    17521 tatgatggta ccctcttcct tcaaaataaa gatggtaatg gcagagctca tggcgaacaa
    17581 ttttccgaaa aataagctca ccgttctcct caagcatcct agggttaaaa tccaaatgac
    17641 catcttttgg aaaaaagcga ccgccagttg tttttaggcg cttgttccaa taagccttgt
    17701 ggtgaaatgg tttgccaaaa tcagccaggg aaacttcttg gacataatta gtgagtgtca
    17761 cgcggtggca ataggctgag attgaccttg tggcggtcca agtcaatctt agagacccaa
    17821 acagttacca agtcacccac tgaaacaact tgactagggt ggttgacaaa ggttttgctc
    17881 atttcagaaa tgtgaataag cccatcttca tgaacaccga tgtctacaaa agcaccaaag
    17941 tcaacgacgt ttctcacagt tccttcaagc ttctggccaa tttccaaatc tttcaaatca
    18001 aggatatctt gacgtaagat tggtgcttca aagtcatcac gaaggtcacg acctggttta
    18061 aggagatcag caatgatatc tttaagggtt tcctgcccaa tagccaatgt ttctgccatt
    18121 tggggaactt gaactgctgc taaa
//
LOCUS       DAXMQE010000036        16587 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.036, whole genome shotgun sequence.
ACCESSION   DAXMQE010000036 DAXMQE010000000
VERSION     DAXMQE010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16587)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16587)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16587
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.036"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            <1..712
                     /locus_tag="ACF4ZO_001487"
     CDS             <1..712
                     /locus_tag="ACF4ZO_001487"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004134 - 4-alpha-glucanotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HFD5487010.1"
                     /translation="NPTYNWSAHEKSNFAWWIYRIQESFKLYDQLRIDHFKGFSDFWE
                     IPAGDKTARNGHWASAPGIALFSAVREALGELPIIAENLGYIDEKAEQLLVSTGFPGM
                     KILEFGLFDITSQSIDLPHYYDRNCVAYTGTHDNEVVNGWYDNLSEEQVHFINNYLHK
                     HADESITKAMLRTIFASVCDTAILCIQDLLDKDGKSRMNMPNTIGGNWQWRMLDGELN
                     QDHKDYLIYLTDLYGRAR"
     gene            747..3011
                     /gene="glgP"
                     /locus_tag="ACF4ZO_001488"
     CDS             747..3011
                     /gene="glgP"
                     /locus_tag="ACF4ZO_001488"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004645 - 1,4-alpha-oligoglucan
                     phosphorylase activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HFD5487011.1"
                     /translation="MTRFTEYVETKLGKSLTQASNEEIYLSLLNFVKEEASHKAKNSA
                     KRKVYYISAEFLIGKLLSNNLINLGIYKDIKEELAAAGKSIAEVEDVELEPSLGNGGL
                     GRLASCFIDSISSLGINGEGVGLNYHCGLFKQVFKHNEQEAEPNYWIEDQSWLVPTNI
                     SYDVPFKNFTLKSRLDRIDVLGYKRDTKNYLNLFDIEGVDYGLIKDGISFDKTQIAKN
                     LTLFLYPDDSDKNGELLRIYQQYFMVSNAAQLIIDEAIERGSNLHDLADYAYVQINDT
                     HPSMVIPELIRLLTEKHGFDFDEAVAVVKNMVGYTNHTILAEALEKWPTAYLNEVVPH
                     LVTIIEKLDALVRSEVSDPAVQIIDESGRVHMAHMDIHFATSVNGVAALHTEILKNSE
                     LKAFYDLYPEKFNNKTNGITFRRWLEFANQDLADYIKELIGDEYLTDATKLEKLMAFA
                     DDKAVHAKLAEIKFNNKLALKRYLKDNKDIELDEHSIIDTQIKRFHEYKRQQMNALYV
                     IHKYLEIKKGNLPKRKITVIFGGKAAPAYIIAQDIIHLILCLSELINNDPEVSPYLNV
                     HLVENYNVTVAEHLIPATDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIA
                     ELAGMENIYTFGKDSDTIINLYATASYVAKDYYDNHPAIKAAVNFIISPELLAFGNEE
                     RLDRLYKELISKDWFMTLIDLEEYIEVKEKMLADYEDQDLWMTKVVHNIAKAGFFSSD
                     RTIEQYNEDIWHSR"
     gene            complement(3268..3888)
                     /locus_tag="ACF4ZO_001489"
     CDS             complement(3268..3888)
                     /locus_tag="ACF4ZO_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3862 domain-containing protein"
                     /protein_id="HFD5487012.1"
                     /translation="MTKKHLLTLLLISFFTSFLVACSTTKDKEPQPSDSEIITPRLHQ
                     AAHQDKRANFEKIKLATVDSSFTGGTSLEELISLFGEPSQHDPKTAGEVTINAYTWQF
                     DQVTLTVNLYQNSSIVKTISNFTFARELGLSQKEYQQLQKGMSYEDAKKILTEPDNYS
                     QASSSDHQTLQAIWVSGLKTDTSGANISLVFENNQLTEMSQVGLEE"
     gene            complement(4250..5338)
                     /locus_tag="ACF4ZO_001490"
     CDS             complement(4250..5338)
                     /locus_tag="ACF4ZO_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFD5487013.1"
                     /translation="MKIKSYKKENGETAYKFLLYAGYVNGKRKYIRREGFKTKQAARE
                     TLISLQAELDKPKSSMTFGALTDQWLKEYEKTVQGSTYLKTERNINKHILPKLDKVKI
                     GDINPLLIQRLTEEWCNDLKYGGKILGLVRNILNLAVRYGYINNNPALPITPPKIKRK
                     RKMNNNFYTLDQLKQFLELVEKTDNIEKIALFRLLAFTGIRKGELLALTWDDLNGNTL
                     SINKAVTRTQVGLEIDVTKTKSSDRLISLDDETLEILQELHETFPTSTLMFKSESGGI
                     MTPSLPRKWLLQIIKGTDLPQITIHGFRHTHASLLFESGLSLKQVQHRLGHGDLQTTM
                     NVYTHITQSAIDDIGTKFNQFVTNKQLD"
     gene            complement(5458..5763)
                     /locus_tag="ACF4ZO_001491"
     CDS             complement(5458..5763)
                     /locus_tag="ACF4ZO_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5487014.1"
                     /translation="MNLENTKLRTKCPSCGKSIILTFHTRRCPKCFLDFKEDYVKRIF
                     YDYESNVANSAFTKVGEKMTSAGEGMEKTGNTIQQIGCIIMLIPIVYILFQLISAFN"
     gene            complement(5773..6561)
                     /locus_tag="ACF4ZO_001492"
     CDS             complement(5773..6561)
                     /locus_tag="ACF4ZO_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S24 family peptidase"
                     /protein_id="HFD5487015.1"
                     /translation="MARGRGKLTPQDEEYKKIISAKINSLLLENNLKQGHLADALEIP
                     RSSFNEYVKGNSLPNPGNVQKIADYFGLMKSDIDPRFAPRKKNHELKIPTSPLVKKIT
                     TTVVELNVPRKQKVLDFATEQLKEQKNKITSIEKKLYEYKVYEKLSAGTGYGYFGDGN
                     YDTVFYDEELDYDFASWVFGDSMEPTYVNGEVVLIKQTGFDYEGGIYAVEWDGQTYIK
                     KVYREKDGLRLVSLNKKYNDKFAPFSEGPRIIGEIVGNFMPKEY"
     gene            complement(6682..6849)
                     /locus_tag="ACF4ZO_001493"
     CDS             complement(6682..6849)
                     /locus_tag="ACF4ZO_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000703682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5487016.1"
                     /translation="MKISNSKDLALAIVASSGPTLSIEDKIKLYEDSVEAIEQHNLPF
                     VLLNSLSLIIL"
     gene            6908..7066
                     /locus_tag="ACF4ZO_001494"
     CDS             6908..7066
                     /locus_tag="ACF4ZO_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5487017.1"
                     /translation="MNWKKLMLGDLEHTFTSCNGKEKTSIEFEGGVLPALLVLGGIAW
                     IIAWFITK"
     gene            complement(7193..7876)
                     /locus_tag="ACF4ZO_001495"
     CDS             complement(7193..7876)
                     /locus_tag="ACF4ZO_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4145 domain-containing protein"
                     /protein_id="HFD5487018.1"
                     /translation="MLLDVVIQFRDCRSTITIDTPSTCPHCGRTMSPQHVGESKSSDN
                     ESYSYQGHFSVIFRCSFDDCLKYFAVEYIHDQIGKGSAVAYFYRPPIRVNLPENVDKV
                     SPAFVEIYSQATIAEQEKLDQIAGVGYRKAAEFLIKDYTISKNPDDSDNIKQIMLGKV
                     ISDYLSDFPKLQALSRSVAWIGNDETHYVRRHNNKDLQDLKRFILAAAQFVAADYDAD
                     DALSFTSTD"
     gene            7974..8213
                     /locus_tag="ACF4ZO_001496"
     CDS             7974..8213
                     /locus_tag="ACF4ZO_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD5487019.1"
                     /translation="MTKMTLRALRVNYSLSAKEVAQELGIHQQTLLKYEIDSTDIPFS
                     LLNELANYYNIDVNNIFLGKKFVLKQIFKNNRLQN"
     gene            8225..8470
                     /locus_tag="ACF4ZO_001497"
     CDS             8225..8470
                     /locus_tag="ACF4ZO_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5487020.1"
                     /translation="MNEIENKLEELEEMVINMDEVDVVIPWKIAKNLLQRAGYLSEEE
                     HRLLSWRLGKSKYAGKRSEKVRNLLEGLRNSGSSENS"
     gene            8637..8978
                     /locus_tag="ACF4ZO_001498"
     CDS             8637..8978
                     /locus_tag="ACF4ZO_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5487021.1"
                     /translation="MRPKRYPYQKNKLIIQSKNAKTKIELDSGKITINAEEIKVGDLA
                     NEISKVQLAKEKVSETIGQDKKPTETVDSRILMLEKEVEGLKGVVGTAYRLATETYHR
                     ISKQSSTSVTE"
     gene            complement(8936..9157)
                     /locus_tag="ACF4ZO_001499"
     CDS             complement(8936..9157)
                     /locus_tag="ACF4ZO_001499"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5487022.1"
                     /translation="MSKLTPKNEIQKVYKDWDTIDTVLKYVFEDPIRTDYVAYIYPKE
                     FKIPKDEIIQELQNNGYSVTEVEDCLEIR"
     gene            9300..9476
                     /locus_tag="ACF4ZO_001500"
     CDS             9300..9476
                     /locus_tag="ACF4ZO_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFD5487023.1"
                     /translation="MKKKLDKILIDKGMSKKELSEKTGISYNTIMNIGKKDISFNKMK
                     KIADDLGVSLDEFR"
     gene            9553..9849
                     /locus_tag="ACF4ZO_001501"
     CDS             9553..9849
                     /locus_tag="ACF4ZO_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFD5487024.1"
                     /translation="MVIEIFGPEFRKKLLEDLIALNMEAIKIAQTKNAKSIEWITMKR
                     LEKETGWGRTKLTQWREQGKFNFKRSSENGKVLYDLADVNRFLRTSGYEKGETT"
     gene            9846..9983
                     /locus_tag="ACF4ZO_001502"
     CDS             9846..9983
                     /locus_tag="ACF4ZO_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5487025.1"
                     /translation="MKLLDFIFAKPKKQEPIKHNTKRLSSEKQWAEFDAYMRKQYGRQ
                     A"
     gene            10064..10393
                     /locus_tag="ACF4ZO_001503"
     CDS             10064..10393
                     /locus_tag="ACF4ZO_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5487026.1"
                     /translation="MKTKIEIMRDFFKENPESTQRQASEKLGFTENTVKQYIWRDVKR
                     GYCIKDEEGRVTYLNIEDELSLINEWKSEIRRELIEQLLSANRHETSSEQIRMNAKTI
                     NQILGEI"
     gene            10393..10587
                     /locus_tag="ACF4ZO_001504"
     CDS             10393..10587
                     /locus_tag="ACF4ZO_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5487027.1"
                     /translation="MEGMKKYINGQIKLIDTIEECVKEKWPEFDDKKVHKISLAIYQG
                     WSLTDINSTLEAIEMDLDRK"
     gene            10584..10868
                     /locus_tag="ACF4ZO_001505"
     CDS             10584..10868
                     /locus_tag="ACF4ZO_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5487028.1"
                     /translation="MRVYVNKKGKPSVEFEFEDRRGGMFDTRLMLKESPLKEEFKSDM
                     YKAIDGVLKKYEDIFDTPIFKELIIGKEEDIRKMIDYDDKFTELFGGIRH"
     gene            10865..11332
                     /locus_tag="ACF4ZO_001506"
     CDS             10865..11332
                     /locus_tag="ACF4ZO_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5487029.1"
                     /translation="MKILSIDPSSNKYDTSTTGIVLLDNANLIKHWVVEYGIRGFQRW
                     FNEIGECLDYDVVIVEKYEVREANGKRDNSVIETIACIQMCYPDAILQRNAGYKSDVP
                     NSLLKALDLYKFSKSHHEDVRASARLALFWAMRNDIKEVIDDIGRIATTKMAS"
     gene            11292..12488
                     /locus_tag="ACF4ZO_001507"
     CDS             11292..12488
                     /locus_tag="ACF4ZO_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HFD5487030.1"
                     /translation="MTLAELQLRKWQAEAIKRSQSVDKGIFLEALGGRGKTICALEIC
                     KVKRVKSVIIVNNRLSILKGWQETIDKFGYDRAIAFMVITDRSLRNKLKTSPKISCDI
                     LIIDEWQNMSSDANVKAYRKIKRNYTIGLSATPIRKKGQNFYPLEKTIWGFANPNNKF
                     DWQKVHGRMVYDVFSYSKEKWEDFKDYESYITKLPNFMRWEEIEDIENAKENNGYEIK
                     FYRKMLDVANPDLLKVFRELNIVHIRGDTAMAKQSFGKKTFERYLIQTGVAIDFPKLK
                     AINKDSPMLLEIDRLIKNAPHGMLIVSESRQIVDIIKERNYHIGIWTGDRKEGIDNQI
                     VVATSQVLGVGVDGLQHQFETIVILDPVGEDSGKYDDYRQLLWRITGSRQQHDVNVIE
                     FYFKGE"
     gene            12489..13259
                     /locus_tag="ACF4ZO_001508"
     CDS             12489..13259
                     /locus_tag="ACF4ZO_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010781715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFD5487031.1"
                     /translation="MFKIPENKPQVPKDTPRNFFIYGETMSGKSFLANEFPNPFIINT
                     DGNSQANSVPSYQLYNHKDKNGKITKSVTEQLGEIILAFQTQKHDYETLVIDVIDDVV
                     DMISFAIQNANGVDSLGDIPFGKGYAMQKDFLKQMASDLKQLPMNVIYISRVDEKFDD
                     KGNVSKVEPSLHKKHFNIFNGNCDLMILTEKIGRNYTREVSRKRKNYYSEQVDDKNIL
                     KILQTIDGAVINGSDPELKKISKTEVTTEANTTEKEIF"
     gene            13279..13815
                     /locus_tag="ACF4ZO_001509"
     CDS             13279..13815
                     /locus_tag="ACF4ZO_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF669 domain-containing protein"
                     /protein_id="HFD5487032.1"
                     /translation="MSLLDIAKQIKKDGYDPRKDKVNNGNQNLPGGEYKVVLKGAEAR
                     VSDSGWESINYAFEVRDVDSDYNGRMQYIMFGTQTEWKAKSGKLLDLTNMVETTIKFF
                     QKAVVLSGDNNLTSDFEDNKTMEEALVRKAVGSKFILVVDEFKKRNGETGYNYDLLEE
                     FNQDDAMTTDIDDDDLPF"
     gene            13832..14629
                     /locus_tag="ACF4ZO_001510"
     CDS             13832..14629
                     /locus_tag="ACF4ZO_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001139684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA primase/polymerase"
                     /protein_id="HFD5487033.1"
                     /translation="MKSMKDYALAYQKLGFSVLPISLNKKKPMISFRDKKAMTAEEIE
                     KFWTNNPQANIALKTDKFFVIDIDVHGANGFESMKKWDGLKYITPTLQAKTPSGGKHI
                     FYFKRDDMTIGQNIGMLPGVDIKAHPNNYVLVAPSTTEKGQYEWDIEKSSENGTITTA
                     TPELLSAISALSKRSELDGVKYRRRIDKNEKTKTSLLFETIATGFGGEGGRNDNLASF
                     VGGLLIRNVDDEYIYTLAKIANENGVDPLDSREVQRTVESIIETDRR"
     gene            14626..15996
                     /locus_tag="ACF4ZO_001511"
     CDS             14626..15996
                     /locus_tag="ACF4ZO_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VapE domain-containing protein"
                     /protein_id="HFD5487034.1"
                     /translation="MIAIGELRSIYEKQLVFTKKKIDGEEVEILKSDSPKNVLLSMKI
                     DSKLSENLRNNSFSQDYEIINPITLDTVELDSGQLPNDFEAYLTIYFENHLGIVYKRQ
                     ALEQGMRTFFAEKSYNPVKEYMEKAYDNWDHKERLHKVFQHWLGVSDNDGLTSKIAEM
                     FFVGCVTKVFQKKVKFDYVLDLVGGQGVGKTSFLQKIGMQWYTDAVTDFQNKDNYDVM
                     LKSLIVNDDEMVATKKTSFAELKSFISKTEMEYRRPYDRRAERYDKNFVIARTTNELE
                     YLRDKTGERRFLPMLANPDLQKKHPLEMSQETVDQLWGEAVNLYKKGYKLSFDEQTEK
                     ALVEYREQFSYKDEIELQILEYLDMLVPDEWETMSLTQRSQFTKCFFNNQKYRDENQE
                     VFKGVKFQTFVSTREILKNVFDVDVARGNLSRKVKVLMDNLDGWMYETKRVNGKSTRG
                     YSRKSE"
     gene            16367..>16587
                     /locus_tag="ACF4ZO_001512"
     CDS             16367..>16587
                     /locus_tag="ACF4ZO_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5487035.1"
                     /translation="MTLVDDFYKQMEPSIKAFLDDNITIADKEEADRFYRSVKYYKKL
                     NRLPPPDVLEWFQQIYTTEEMIMLIKQSYR"
BASE COUNT         5787 a         2643 c         3143 g         5014 t
ORIGIN      
        1 aaatccaacc tacaattggt ctgctcatga aaagtctaat tttgcatggt ggatttatcg
       61 tattcaagaa agttttaaac tatatgatca gctaagaatc gatcatttta aaggcttctc
      121 agatttttgg gaaattcctg ctggtgataa aactgctaga aatggccatt gggcctcagc
      181 cccaggtata gcattatttt ctgcggttcg tgaggcctta ggagagcttc ctatcatcgc
      241 agaaaacctt ggttatattg atgaaaaagc agagcagcta ttagtatcaa caggctttcc
      301 tggcatgaag atattagaat ttggtttatt tgatataacg agtcaaagta tagatttacc
      361 acattactat gaccgtaatt gtgtcgctta cacagggact catgataacg aggtggttaa
      421 cggatggtat gacaatctta gtgaagaaca agtacacttt ataaataact atcttcacaa
      481 acatgcagat gaaagtatta caaaagccat gctaagaaca atctttgctt ctgtttgtga
      541 tacagccatt ctttgcatcc aagatttatt agataaagat ggtaagagtc gtatgaatat
      601 gccaaataca attggaggta attggcaatg gcgtatgctt gacggtgaat tgaaccaaga
      661 tcacaaagat taccttattt atttaacaga tctttatggt cgcgcaagat aatatttaaa
      721 tgttacatta ttgaaaagag gaagacatga cacgctttac agaatatgtt gaaactaaac
      781 taggaaaatc acttacacaa gccagcaatg aagagattta tctatcatta ttaaactttg
      841 tcaaagaaga agctagccac aaggctaaaa attctgctaa acgcaaagtt tactatatct
      901 cagcagagtt tttgattggt aaattactat caaacaacct aattaaccta ggaatttaca
      961 aagacatcaa agaagaattg gcagctgctg gcaaatctat cgcagaagtc gaagatgttg
     1021 aattagaacc atcactaggt aatggtggtt tagggcgttt ggcatcatgt ttcattgact
     1081 ctatttcatc tcttggtatt aatggtgaag gggttggttt aaactatcat tgtgggttgt
     1141 ttaagcaagt cttcaaacac aatgagcaag aagctgaacc aaactactgg attgaagacc
     1201 agtcatggtt ggttcctaca aacatttcgt atgatgtgcc ttttaagaac ttcaccttga
     1261 aatctcgtct tgatcgtatt gatgttttgg gttacaaacg cgacactaaa aactacctta
     1321 acttgtttga tatcgagggc gttgattacg ggttaatcaa agacggtatt tcatttgata
     1381 aaacgcaaat tgctaaaaac ttgaccttgt tcctctaccc agacgattct gataaaaatg
     1441 gggaattgct ccgtatttac caacagtact ttatggtgtc aaatgcagcg caattaatca
     1501 ttgatgaagc tatcgaacgt ggttctaacc ttcatgatct tgcagactac gcttacgtgc
     1561 aaattaatga cacgcatcca tcaatggtca tcccagaatt aattcgtctc ttgactgaaa
     1621 aacatggctt tgactttgat gaagcggtag ctgttgtgaa aaatatggtt ggttacacta
     1681 accacactat tcttgcagaa gcccttgaaa aatggccaac tgcttactta aacgaagtag
     1741 tgccacactt ggtaaccatc attgaaaaat tggatgctct tgttcgttca gaagtgtctg
     1801 acccagctgt tcaaattatt gacgaatcag gtcgtgtgca catggcccat atggatattc
     1861 attttgcaac aagtgtcaat ggggtagcag cactccacac agaaatcttg aaaaacagcg
     1921 aattaaaagc tttctatgac ctttacccag aaaaattcaa caacaaaacc aacgggatta
     1981 ctttccgtcg ttggctagaa tttgctaacc aagacttggc tgattacatt aaagaactta
     2041 ttggcgatga gtacttgact gacgcaacaa aactagaaaa attgatggcc tttgcagatg
     2101 acaaagctgt tcatgctaaa ttggctgaaa tcaaattcaa caacaaatta gctcttaaac
     2161 gttaccttaa agacaataaa gacattgagc ttgatgaaca ttctattatt gatacccaaa
     2221 tcaaacgttt ccatgagtac aaacgtcaac agatgaatgc tctttacgtg attcacaaat
     2281 atttggaaat taaaaaaggc aaccttccaa aacgtaaaat cactgttatc tttggaggta
     2341 aagcagcgcc tgcttacatc attgctcaag acatcattca cttgatcctt tgcttgtctg
     2401 aattgattaa caatgaccct gaagtaagcc cataccttaa tgtgcatcta gttgaaaatt
     2461 acaacgtgac agtagcagag cacttgattc cagcaactga tatttctgag caaatttcac
     2521 tagcatccaa agaagcttct ggaactggta atatgaaatt catgcttaac ggtgctttaa
     2581 cacttggtac aatggacggt gctaacgtag aaatcgctga gcttgcaggc atggaaaata
     2641 tctacacctt tggtaaagat tctgatacca tcatcaacct ttatgcaact gcttcttatg
     2701 tagcaaaaga ttactatgat aaccaccctg ctattaaagc agcagtgaac tttattatca
     2761 gtccagaatt gctagcattt ggcaacgaag aacgtcttga tcgtctttat aaagaattga
     2821 tttcaaaaga ctggttcatg accttgattg accttgaaga gtacattgaa gtgaaagaaa
     2881 aaatgttagc agactatgaa gaccaagatt tatggatgac aaaagtggtc cataacatcg
     2941 caaaagctgg attcttctca tctgaccgta ccattgagca gtataacgaa gatatttggc
     3001 attcacgata aaaaataata attgcaatgt ggggtagcgg taccgtaaca tgcttaaact
     3061 aaattataag acagtagttt ctgctgtctt atgatttttc ttcagactta ggttaattat
     3121 tacattaagc gtaaagcaag tctgtttatc gatctatgga ggtaattata agaaactaca
     3181 ctaaagtttt ttattaaaat gatataaaaa gattgatttc ggtgtacatc gaaatcaatc
     3241 tttttagcaa aatatattac gcatttttta ttcttcaagt cctacctgag acatttctgt
     3301 taactgatta ttttcaaaaa cgagagaaat attagctccg cttgtatctg tctttaagcc
     3361 actaacccaa atcgcttgca aagtttgatg atcactagat gacgcttggc tataattatc
     3421 aggttctgtt aagatctttt tagcgtcttc ataagacatt cctttttgta attgttggta
     3481 ttccttttgc gataagccta actctcttgc aaaggtaaaa ttagagatgg ttttaacaat
     3541 actactattt tgataaagat taacagtgag agtaacttga tcaaactgcc aagtataagc
     3601 gttgattgtt acttcgcctg ctgtttttgg atcatgttgg ctaggctctc caaagagtga
     3661 aataagttct tcaaggcttg ttcctcctgt aaatgaggaa tcaacagtcg caagtttaat
     3721 tttttcaaag ttagcgcgtt tatcttgatg agcggcttgg tgtagtcggg gagtaatgat
     3781 ttctgaatca gacggttgag gttctttatc tttcgttgtt gaacaagcta ccaaaaagct
     3841 agtaaaaaaa gagatgagaa gaagtgttag taagtgtttt tttgtcatat gttatttcct
     3901 aaactatttt tgctgtatta tatcataaat tataaacaag atatagctat gattccccat
     3961 aacgcatgcg ctatggggaa tttagtacta ttttgattct ttttttagat attcatgaaa
     4021 aaaatggtca aaaagctctg atatgacaag gttttgagtg gtattgatgg agtatcggtc
     4081 agcgtgatgg tatggctata gggataacgg aaactcatga acaagacaaa aagaaaaaac
     4141 cttgatgtaa caaggtttta gtaagttatg attacttacg gtaagcattg atggagccgg
     4201 tgggagttac ttgaacgttg ttaaattaac gtttgttgag aattagttgt caatctagtt
     4261 gcttgttagt aacaaattga ttgaatttag ttccaatgtc atcaattgct gattgcgtga
     4321 tgtgagtata tacgttcata gttgtctgta aatctccatg tcctaatcta tgttgcacct
     4381 gtttcaagga tagacctgat tcgaaaagta agcttgcatg agtgtgcctg aaaccatgaa
     4441 ttgtgatttg tggtaagtct gtccctttga taatttgcaa tagccatttt cgtggtaaac
     4501 ttggcgtcat aattccacct gattcagatt tgaacataag agtagaagta ggaaaagttt
     4561 catgaagttc ttgtaaaatt tccaaagttt catcatctaa gctgattaat ctatcgctcg
     4621 attttgtctt cgtaacatct atttctagtc caacttgagt acgtgtgaca gctttattaa
     4681 ttgatagagt attaccattc aaatcatccc aagttagtgc cagaagctcc ccttttcgta
     4741 ttccagtaaa tgctaataat ctaaataagg ctattttttc aatgttatca gttttttcaa
     4801 ctagttcaag gaattgttta agttgatcaa gtgtataaaa attattattc atttttcttt
     4861 tcctttttat ttttggaggt gtaattggca aagctggatt gttattgata tatccgtatc
     4921 taacagctag atttaagata ttcctaacaa gcccaagaat ttttcctcca tattttaaat
     4981 cgttgcacca ttcttcagta agccgctgga taagtagtgg attgatgtct ccaatcttca
     5041 ctttatcaag ttttggcaaa atatgtttat taatatttct ttctgttttt aagtaggtac
     5101 tgccctgaac ggttttttca tattccttta gccattgatc tgtcaatgct ccaaatgtca
     5161 tacttgattt aggtttatca agttcagctt gtaaactaat taaggtttcc cttgcagcct
     5221 gcttagtttt gaaaccttct cgcctaatat attttctctt tccattaaca taaccggcat
     5281 acaaaagaaa tttataagca gtttcaccat tttccttttt atatgattta attttcattg
     5341 cataccatct ttcaatttga taaaataggt acaagaaaat gaccttttta atggttgttt
     5401 cttatactgt cttgcctcac gctcagagtc gccaaacttt gagagcgtgg ggctttttta
     5461 gttaaacgcc gaaataagct ggaacaaaat gtacactata ggaataagca tgataatgca
     5521 acctatttgt tgtattgtgt tacctgtctt ttccatcccc tcgcctgcac ttgtcatttt
     5581 ttctccaact tttgtaaaag cagaatttgc tacgtttgat tcataatcat aaaaaattcg
     5641 cttcacataa tcttctttaa aatctaaaaa acatttaggg catcttctag tgtgaaaagt
     5701 aagaataata gacttgccgc aactcggaca ttttgttctt agttttgtat tttctaaatt
     5761 catttatcta cctcagtact ctttaggcat aaagttaccg acaatttccc ctattatacg
     5821 agggccttca ctaaaaggag caaacttgtc attgtatttt ttatttaagg acacaaggcg
     5881 caagccatcc ttttctctgt aaactttctt aatataggtt tgtccgtccc actctacggc
     5941 atagatgcca ccttcataat caaagccagt ttgttttata agcacaacct caccattcac
     6001 ataagttggt tccatagaat caccaaaaac ccaagaggca aaatcgtaat ctaattcttc
     6061 gtcgtaaaaa acagtatcat agttcccatc accaaaatac ccataacctg tacctgcgga
     6121 aagtttctca tagactttgt attcatatag ttttttctct atcgaagtaa ttttgttttt
     6181 ttgctctttc aattgttctg ttgcaaagtc taaaactttt tgtttacgag gaacatttaa
     6241 ttctacaact gttgtggtta tttttttgac gagtggagaa gtagggattt tgagttcgtg
     6301 atttttctta cgaggtgcaa atctaggatc tatatcagac ttcattaacc cgaaataatc
     6361 agctatcttt tgaacgttac caggattagg taaggaattt cctttgacat attcattaaa
     6421 actacttcgt ggaatttcca atgcatcagc taaatgtcct tgttttaaat tgttttctag
     6481 caataaactg ttaattttag cagaaattat ctttttgtat tcctcgtctt gaggtgttaa
     6541 cttccctcgt cctcttgcca tattattttc ctttcgattt ttatacttat atagtatcgt
     6601 tttaaatcgt atttgtaaat aaaattttta aaaaaattcg ttttttttcg tttttatact
     6661 tgacattcgt tttaaaacgg actacaatat aatcaagctt aaggaattaa gcaaaacgaa
     6721 aggtaaattg tgttgttcaa tagcttccac agagtcttcg taaagtttga ttttatcttc
     6781 gatagacaaa gtagggccag aagaagcgac aatagcgaga gctaaatctt ttgaattaga
     6841 aattttcatt agcttatcct cttttccact aggataagtt gattataaca tttttaggag
     6901 gcacaaaatg aattggaaaa aactaatgct tggcgactta gagcacacgt ttactagttg
     6961 taatggcaaa gaaaaaacaa gcatcgaatt tgaaggtggc gtattaccag ctctgttagt
     7021 gttgggcggt atcgcttgga taatcgcttg gtttattaca aaataaaaac tcccaagagg
     7081 gagtggaaag gagtaacgat atgaacgaac tagaaagaac agcccttaat gaaatcatga
     7141 ggacagtgac ttatatagcg gagaagctgg ataaaattga ttctaagatt tctcagtctg
     7201 tagaagtgaa cgatagtgca tcgtcagcgt cgtagtctgc cgcaacaaat tgagcagctg
     7261 ctaaaataaa acgtttgaga tcctgcaagt ctttattatt atgtctacga acataatgag
     7321 tttcatcgtt accaatccac gctaccgagc gagatagagc ttggagttta gggaagtcgg
     7381 agagatagtc actaattact tttccaagca taatttgttt gatgttgtcg ctgtcgtcag
     7441 gattctttga tattgtataa tctttgatta aaaactcagc agctttacgg taaccaacac
     7501 ctgcaatttg atcgagtttt tcttgctctg caattgtagc ttgggagtat atctctacaa
     7561 atgctggcga cactttatca acgttttcag gaagattcac tctaataggt ggacgataga
     7621 agtaggcgac agctgatcct ttaccaatct gatcgtggat atactctaca gcaaaatatt
     7681 ttaagcaatc atcgaaagag caacggaata tcactgaaaa atgcccctga tatgaataac
     7741 tttcattgtc agaacttttg ctttcgccaa cgtgttgagg ggacatagtt cgaccacagt
     7801 gggggcaagt cgaaggtgta tcaattgtga ttgtacttct acaatctcta aattgtataa
     7861 ctacatcaag caacattatt atttctctcc aatcgtttta tttaaattat accacagaaa
     7921 attttaaagc tatgttgttt tggataattc taaattagaa agggggtggg ggaatgacga
     7981 aaatgacact aagagcctta cgcgttaact atagccttag cgcaaaagaa gtagcgcaag
     8041 aacttggtat tcatcaacaa actttactaa aatacgaaat tgatagtaca gacatcccgt
     8101 ttagtttatt aaatgaattg gcaaattatt acaatattga tgtaaataat atttttttag
     8161 gcaaaaaatt cgttttaaaa caaatattta aaaacaaccg cctacaaaac tagaaaggac
     8221 acatatgaac gaaatagaaa acaaactaga agaacttgaa gaaatggtaa taaacatgga
     8281 tgaagtagat gtagtgattc catggaagat agcaaaaaac ctgctacaaa gagcaggtta
     8341 cttatcagaa gaggaacatc gcctactaag ttggagactt ggaaaatcaa aatatgcagg
     8401 caaacgttcc gaaaaagtcc gcaatttgct agagggactt aggaatagtg gaagttccga
     8461 gaatagctga taattttaat tctgttgttt ggtcattgtg catgaaaatg agagtttcat
     8521 ttttgcgatt aggctcaatc caatgatcaa taacaaagtc tccgataaga ctatattcat
     8581 ttagctatcc tccttcctaa taggataact acattataca acagaaagga aaccacatga
     8641 gaccaaaacg atatccgtat caaaaaaata aattaattat ccagtcgaaa aacgcaaaga
     8701 caaaaattga attagatagc ggaaaaataa ctatcaatgc tgaagaaatc aaggttggtg
     8761 atttagcaaa cgaaatttca aaagtgcaac tagccaaaga aaaagtatct gaaactattg
     8821 gtcaagataa aaagcctact gaaacagtag actctaggat tttaatgctt gaaaaagagg
     8881 tcgaaggatt gaaaggagtt gttggaacag catatcgact tgctacagag acttatcatc
     8941 gaatctccaa acaatcttct acctcagtaa ctgagtagcc gttgttctga agctcctgga
     9001 ttatttcgtc tttaggaatt ttaaactcct taggatatat ataagcaaca tagtctgttc
     9061 tgattggatc ttcaaataca tattttaaaa cagtatcgat agtatcccaa tctttgtaaa
     9121 ctttttgaat ttcattcttt ggagttaatt tactcataac cttccctcct ttccgtaatt
     9181 ttttgaatac aacggtgaga ggtcatattc gaatgaatta tatcagaaag gaacgaaaga
     9241 cacaatatat tgttttatcg atatataaaa aacacaacat attgaagttt ggataatcta
     9301 tgaagaaaaa actagacaaa attctcattg ataaaggaat gagtaaaaaa gagttatcgg
     9361 agaaaacagg aattagttac aacaccatta tgaatatcgg taaaaaagat atttcgttta
     9421 acaaaatgaa aaaaattgcc gatgacttgg gcgtcagctt agacgaattt agatagcaaa
     9481 aaagtccgac gggaaacgga ctcaaaacaa attttaattt acttaattat aacataagag
     9541 agagggaaaa ctatggtcat tgaaatattt ggacctgagt ttagaaaaaa actgcttgaa
     9601 gatttaatcg ctctaaatat ggaagcgata aaaatagcgc agaccaaaaa cgccaagtct
     9661 attgaatgga taaccatgaa gcggctagaa aaagaaactg gatgggggcg aactaaattg
     9721 acccagtgga gagaacaagg gaaatttaac tttaaaaggt catcagaaaa cgggaaagta
     9781 ctatatgacc tagcagatgt taatagattt ttacggacca gtggatatga aaaaggagaa
     9841 acaacatgaa actattagat tttatttttg caaaaccaaa aaaacaggaa ccgattaaac
     9901 acaatactaa gcgattgtca tctgaaaagc agtgggccga atttgatgcc tatatgagga
     9961 aacagtatgg acgacaagct taatcagata ttgatagcca tgcgaaacta ccgcacaaat
    10021 ggtgatgata gcaagtattt agaggatatg gaggtcattt taaatgaaaa caaaaattga
    10081 aatcatgcgt gattttttta aagaaaatcc tgaatcaact caacggcaag cctcagaaaa
    10141 gcttggattt acggaaaata cagttaaaca atatatttgg agagatgtta agcgtggcta
    10201 ctgtattaaa gacgaagaag gtcgtgtaac ttatctaaac attgaagatg aattatcgct
    10261 tattaatgaa tggaaaagtg aaattagaag agaattgatt gaacagttac tatcagctaa
    10321 tcgacatgaa acgtcaagcg aacaaattcg tatgaacgct aaaacaatca atcagatttt
    10381 aggagaaatt taatggaagg tatgaaaaag tatatcaatg gtcagattaa actaattgat
    10441 actattgaag aatgtgtcaa agaaaaatgg cctgaatttg atgataaaaa agtacataag
    10501 atatctttag ctatttacca aggatggtct cttacagata ttaatagcac actcgaagcg
    10561 atagaaatgg acttggatag aaaatgagag tttatgtaaa caaaaaaggt aaaccatctg
    10621 ttgaatttga gtttgaagat cggcgcggtg gcatgtttga tacaagatta atgttaaaag
    10681 aatcaccgct caaagaagaa tttaaatctg atatgtacaa ggcaattgat ggtgttttaa
    10741 aaaaatatga agacattttt gatactccta tttttaaaga attaataatt gggaaagaag
    10801 aagatattag aaaaatgatt gattacgatg ataaatttac cgaacttttt ggagggatta
    10861 gacattgaag attctttcga ttgatccatc gtcaaataag tatgacacaa gcacaacagg
    10921 tattgttcta ttagataatg ctaatttaat taaacattgg gttgttgaat atggtatcag
    10981 agggtttcaa agatggttta acgagatagg tgaatgttta gattacgatg tcgtcattgt
    11041 tgaaaaatat gaggttcgtg aagcgaacgg taagcgtgac aattcagtca tagaaactat
    11101 tgcttgtatt caaatgtgtt atccagatgc tatccttcaa agaaatgctg gttacaaatc
    11161 agatgtacct aactcactgc ttaaagcgct tgacctctat aagtttagta aaagtcatca
    11221 tgaagatgtc agagcatcag ctcgattagc tttgttttgg gcaatgagaa atgacataaa
    11281 ggaggtgatt gatgacattg gcagaattgc aactacgaaa atggcaagct gaggcaatca
    11341 agagaagtca atcagtcgat aaagggatat tcttagaggc tttaggtggc agaggtaaga
    11401 ctatctgcgc tttggaaatt tgcaaagtga aacgagttaa atcggtgatt attgtcaaca
    11461 atcgtttatc gatactaaaa ggctggcaag aaacgattga taaattcggt tatgacagag
    11521 ctatagcttt tatggtaatt accgatagat ctctgagaaa taagctaaaa acaagcccta
    11581 aaatatcctg tgacatactc attattgacg agtggcagaa tatgtcgagt gatgcgaatg
    11641 ttaaggcata tcgcaaaata aagcgcaatt acactatagg gttatcagca actcctatcc
    11701 gtaaaaaagg tcaaaatttt tatccattag aaaaaacgat ttggggattt gctaatccta
    11761 ataataagtt cgactggcaa aaggtccatg ggcgaatggt ttatgatgtg ttttcttact
    11821 caaaagagaa gtgggaagac ttcaaagact atgaatcata catcacaaaa ttacctaact
    11881 tcatgcgctg ggaagaaatt gaagacatcg aaaacgcaaa agagaataac ggttatgaga
    11941 tcaagttcta ccgaaagatg ttagatgtcg caaatcctga tttattaaaa gtattcagag
    12001 aattaaacat cgttcacatt agaggtgata ccgctatggc taagcaatca ttcggcaaga
    12061 aaacttttga aagatacctg atccaaactg gtgtagcaat tgactttcca aaactgaaag
    12121 ctattaataa agatagtcca atgcttttgg aaatcgatag gctaattaaa aatgcacctc
    12181 acggaatgtt aattgtgagt gaatcacgac aaattgttga catcataaaa gaacgaaatt
    12241 atcatatcgg aatttggact ggagatagaa aagaaggtat tgataatcaa atagttgtag
    12301 caacaagcca ggttttaggt gttggtgttg atggtttaca acatcaattt gaaacgatag
    12361 tcattcttga tccagtaggt gaagatagtg gaaagtatga cgactaccgc caattgttgt
    12421 ggcgaataac gggaagtcgt cagcagcatg acgtgaatgt catagaattt tattttaaag
    12481 gagaatagat gtttaaaata ccagagaaca aacctcaagt tccaaaagac acgcctagaa
    12541 atttctttat ctacggtgaa acaatgagtg gtaaatcttt cttagctaat gaatttccaa
    12601 acccatttat tatcaacacg gacggaaatt ctcaagctaa ttcagtacca tcgtatcaac
    12661 tttataatca taaagataag aacgggaaaa taacgaaaag cgtaacagag caactcggcg
    12721 aaatcattct agctttccaa acacaaaaac acgactatga gacattagtc attgatgtca
    12781 ttgatgatgt cgttgacatg atttctttcg caatccagaa tgcgaacggc gttgattcat
    12841 taggagatat tcctttcgga aaaggatatg caatgcaaaa ggatttttta aagcaaatgg
    12901 catccgattt aaaacaacta ccaatgaatg tcatttacat ttctagggtt gatgaaaaat
    12961 ttgatgataa aggaaatgtt tccaaagttg agccgtcatt acataaaaag cacttcaata
    13021 tctttaacgg aaattgcgac cttatgattt tgactgaaaa aataggtaga aattacacta
    13081 gagaagtttc tagaaaaaga aagaattatt actcagaaca agttgatgac aaaaacatct
    13141 taaaaatttt acaaacaata gacggtgcag ttataaatgg atctgatcca gaattaaaaa
    13201 agatatcaaa aacagaagta actaccgaag ctaacactac agaaaaagaa attttttaat
    13261 taaaaaggag aaaacaatat gagtttatta gatatcgcaa aacaaatcaa aaaagacggt
    13321 tacgacccac gtaaggacaa agttaataat ggcaatcaaa acctgcctgg cggtgaatac
    13381 aaggttgtct tgaaaggtgc tgaagctcgt gtatcggaca gcggttggga aagtatcaac
    13441 tacgctttcg aagtccgtga tgttgatagc gattataatg gtcgtatgca atatattatg
    13501 tttggaacac aaacagaatg gaaagcgaaa agcggcaagt tattggactt aacaaatatg
    13561 gttgagacaa caattaaatt cttccaaaaa gccgtggtct tgtctggtga taataactta
    13621 acatcagact ttgaagacaa taaaacaatg gaagaagctt tagtgagaaa agcggttgga
    13681 tctaaattta tcttagtagt agatgaattt aaaaagcgca atggcgaaac tggttacaac
    13741 tacgacttgt tagaagaatt taaccaagat gacgctatga ctaccgatat cgacgatgat
    13801 gatttaccgt tttaataaat agaggtgagc tatgaagtcg atgaaagatt atgctttagc
    13861 ttatcaaaaa ctcggcttct cagtcttgcc gataagctta aacaagaaaa aaccaatgat
    13921 tagttttcga gacaaaaagg caatgactgc tgaagaaatc gaaaagtttt ggacgaataa
    13981 tccacaagct aacattgctt taaagactga taaattcttc gttattgata ttgatgttca
    14041 cggcgccaat ggttttgaat cgatgaagaa atgggatggt ttaaaataca tcacaccaac
    14101 gttgcaagct aagacgccaa gcggcggtaa acatatcttc tattttaagc gtgacgatat
    14161 gactattggt caaaacatcg gaatgttgcc tggtgttgat atcaaagcac acccaaacaa
    14221 ttatgttcta gtcgctccat ctacgacaga aaaaggtcag tacgaatggg atatcgaaaa
    14281 gtcatcagag aacggtacta taacaaccgc aactcctgaa ttattaagtg caatcagtgc
    14341 attgagcaaa cggagcgaat tagatggcgt gaaatatcgc agacgtatag acaaaaatga
    14401 aaaaacaaag acaagtttgt tatttgaaac tatcgcaacg ggtttcggtg gagaaggtgg
    14461 acgtaacgac aacctagcta gctttgttgg tggattgtta attagaaatg ttgatgatga
    14521 atacatctac acactcgcaa agatagcaaa tgaaaatggt gttgatccat tagatagcag
    14581 ggaagttcag cgaactgtag agagtataat agaaacggat aggaggtgat agcgattggc
    14641 gagctaagaa gcatttacga aaaacaacta gtatttacaa agaaaaaaat agatggtgaa
    14701 gaagttgaga ttttaaaatc agacagtcca aaaaatgttt tattgtcgat gaagattgat
    14761 agcaaattga gcgaaaatct taggaataat tcgttttcac aagattatga aatcataaat
    14821 ccaattacct tagataccgt agagttagat agcggacaat taccaaatga ctttgaagct
    14881 tacttaacca tttattttga aaatcattta ggtattgtct ataagcgcca agctttagag
    14941 caaggcatgc gcactttttt tgccgaaaaa tcatacaatc cagttaaaga gtacatggaa
    15001 aaagcttatg ataattggga tcataaagaa aggctgcata aagtttttca gcattggctt
    15061 ggggtctctg ataacgacgg tttaacttca aaaattgctg aaatgttctt tgtaggttgt
    15121 gtcactaaag tttttcaaaa aaaagttaaa ttcgactatg ttttagattt agtaggcggt
    15181 caaggagtcg gtaagacatc gttcttacaa aaaataggta tgcaatggta tacggatgct
    15241 gtgactgact ttcaaaacaa agacaattac gatgttatgc ttaaaagttt aatcgtaaac
    15301 gacgatgaga tggtagcaac taaaaaaact tcttttgcgg aattgaaatc attcatctca
    15361 aaaacagaaa tggaatatcg cagaccttac gaccgaagag ctgagaggta tgataaaaac
    15421 ttcgttatcg ctaggaccac taatgagctt gaatatctta gagataaaac tggtgaacgt
    15481 aggtttttac cgatgttggc aaatcctgac ttgcaaaaaa aacatccttt agagatgtca
    15541 caagaaactg ttgatcaatt atggggcgaa gctgtaaacc tttataaaaa aggttataaa
    15601 ttaagctttg atgaacaaac agaaaaagcg ttagtcgagt atagagagca attttcttac
    15661 aaggacgaaa ttgaacttca gatattagag tatttagaca tgcttgttcc tgatgaatgg
    15721 gaaacgatgt cattaactca acgtagtcaa tttactaaat gttttttcaa taatcaaaaa
    15781 tacagagacg aaaatcagga agtttttaaa ggggttaaat tccaaacctt tgtgtcgact
    15841 agagaaatcc taaaaaatgt ttttgatgtc gatgtcgcaa gaggcaatct cagtagaaaa
    15901 gtaaaagtcc tcatggataa tcttgatgga tggatgtatg aaacaaaaag agttaacgga
    15961 aaatcaacaa ggggttattc aagaaaaagt gaataattat ggatacatca cgtcatgtaa
    16021 catagatgta gtgatgtaac aaaataggtt ttttaataca tcatgttaca tcactgatgt
    16081 aacatgcgtc aaacccttgg gagagtaggt ttataggatg tttttaagca tacttaacaa
    16141 aaacagtgat gtaacaccct tcagacttag agccacaagg gtttagaaga taatatatat
    16201 agatgttaca tcatatcact ctataaaaac tatatatttt tattaatagt tataaatgcc
    16261 tttatatcaa cattcttaat ttattatttt ataagtgttc gaaaaatgat gtaacatgta
    16321 acagtaaata attatgttaa taattataca taaatggaga taatcaatga cattagtaga
    16381 tgatttttac aaacaaatgg agccgtcaat caaagcgttt ttagacgata acattaccat
    16441 cgcagacaaa gaagaagctg acagattcta tagatctgtc aaatactata aaaaactaaa
    16501 cagattgccg ccacctgatg tattggagtg gtttcagcaa atctacacga cagaggaaat
    16561 gataatgtta atcaagcagt cttaccg
//
LOCUS       DAXMQE010000037        15978 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.037, whole genome shotgun sequence.
ACCESSION   DAXMQE010000037 DAXMQE010000000
VERSION     DAXMQE010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15978)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15978)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15978
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.037"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            15..500
                     /locus_tag="ACF4ZO_001513"
     CDS             15..500
                     /locus_tag="ACF4ZO_001513"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFD5487036.1"
                     /translation="MTDIKILDACCGSRLFWFDKNEPHTTFMDVRQEKFEMHGKKINV
                     NPDVIGDFRDMPFESNSFNLVVFDPPHLKYVGQNSIMKAQYGQLDKENWKEDISKGFE
                     ECMRVLKVGGTLVFKWSDCQVNVREVLSAIPFKPLFGQQRGTTHWMTFVKFAELTGNG
                     R"
     gene            504..731
                     /locus_tag="ACF4ZO_001514"
     CDS             504..731
                     /locus_tag="ACF4ZO_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5487037.1"
                     /translation="MNKQNFEKLDKVKELLDELKIPEFMAPLLVGNQIMEIINDLHNE
                     PDQFGAQVLLPSPDKKYKFAVRICREENLED"
     gene            756..941
                     /locus_tag="ACF4ZO_001515"
     CDS             756..941
                     /locus_tag="ACF4ZO_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5487038.1"
                     /translation="MAENKTGMMTLPIDYANRALAKEEILDELVEREIVDVDLLIELA
                     EDNPFWMSALNFKRGTK"
     gene            1177..1611
                     /locus_tag="ACF4ZO_001516"
     CDS             1177..1611
                     /locus_tag="ACF4ZO_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family phage packaging/lysis
                     transcriptional regulator"
                     /protein_id="HFD5487039.1"
                     /translation="MTFFPEIDIQKTKSNAKRKLREYPRWRRIANDVDTQKVTATYSF
                     EPRQSHGVPSKPVERLALNRVSAEQELDAIEQAVSMILEPERRRILYDKYLAPYKKAD
                     KVIYTELCMSESFYYDTLDIALLAFAELYREGVLLVEEGVFS"
     gene            1915..2256
                     /locus_tag="ACF4ZO_001517"
     CDS             1915..2256
                     /locus_tag="ACF4ZO_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease signature motif containing
                     protein"
                     /protein_id="HFD5487040.1"
                     /translation="MRPQKLTIAGGRRTTVDYDDRSAEYRDYNRNRWKYDKQVKQFYN
                     SRIWRETSKQVLLQNDYICAMCGGEATMTDHIVSVKQDWNKRLDLNNLQASCKACNDS
                     KAIRERRKNNY"
     gene            2428..2895
                     /locus_tag="ACF4ZO_001518"
     CDS             2428..2895
                     /locus_tag="ACF4ZO_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
                     /protein_id="HFD5487041.1"
                     /translation="MGRNLKLVETTKKHLTKEEKIVRETAQNKASDGFKKLQKTPPEH
                     FNNVAKYEYRRIIEDLQNLPLRNLDRGLLELYCTWYAIYKETSRKLDEVGYFTNDPDK
                     GIIPSPLILTLEKATANIRSSASQLGLTVDSRMKMFIPKEEEKPKSIFDKFGG"
     gene            2910..4664
                     /locus_tag="ACF4ZO_001519"
     CDS             2910..4664
                     /locus_tag="ACF4ZO_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="terminase TerL endonuclease subunit"
                     /protein_id="HFD5487042.1"
                     /translation="MTIEYDYSAIDDFYKDDAFYYAKMVVDEQIKSSKKVFKACLRHL
                     NDLKKIDGDNFKFIYLPEKAADPINFIEILPDVKTGKPYPLAMFQKFIIGNLYGWRKK
                     TDHSLRRFRKAMISVARKNGKTILIAGILLYEFLFGHNPSMSRQLFCTANDRTQAKIA
                     WDMAKKQLSSLRAKDADVRKATKIVRDELKNLHDESYIRALSRDTGAVDGFEPYVGVL
                     DEFAASKTNEMLELLESGQGQLDNPFILIISTAGMDLNVPMHTIEYPYITKILDGEIT
                     DEGYFGYVAEQDNEEEIKDESNWIKSNPILEVEALHDKLMDYLRTRRRVSLETGEINK
                     VLIKNFNMWRQSSEESYIDKTTWELARIDKPDTNKRRVWLGVDVGRVSDLFAITPVVM
                     MDDFWYIDSFSFVATKYGLTAKEKRDGVSYSNLECQGYCEITTLESGVIDDERVLEKI
                     EEMVYSNDWEINGICFDPYQFGTLLTMIEKRHPEWPLIEVSQTTMVLNMPTKQFRDDL
                     KKGKIKHSGNPLLTMAVNNAYIKTDNNGMRIDKNKNSNKIDPLDAALDGYAVCYLEPF
                     DGSGYWTNEKIIGGESLF"
     gene            4661..4831
                     /locus_tag="ACF4ZO_001520"
     CDS             4661..4831
                     /locus_tag="ACF4ZO_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5487043.1"
                     /translation="MIDFILKNIHTLILLAGLGLLMYGLFLFGDKVGFIASGLILIVL
                     AIYVDSVGGKRE"
     gene            4824..5048
                     /locus_tag="ACF4ZO_001521"
     CDS             4824..5048
                     /locus_tag="ACF4ZO_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5487044.1"
                     /translation="MNKRIKKKRKLETAIVLLIKEVAELRSIVSANAKATNNELAAVK
                     SAILDNQVAIKSIGDEVGHIKQNYKRKWRK"
     gene            5082..6302
                     /locus_tag="ACF4ZO_001522"
     CDS             5082..6302
                     /locus_tag="ACF4ZO_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000007730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HFD5487045.1"
                     /translation="MSFFQPLGSSKVSYDDYISSVLAGDVSQKYLGVSALKNSDILTA
                     TSIIAGDIARFPLVKKDVNGDIIHDEDINYLLNVKSTKNASARTWKFAMAVNAILTGN
                     SFSRILRNPKTNQALQFQFYRPSETTVEETDNHEIVYTFTDTLTAKQVKCFAHDVVHW
                     KFFSHDTILGRSPLLSLGDEIDLQTGGINTLIKFFKDGFSSGILTMKGAQLSGDARQR
                     ARQEFEKMREGSVGGSPLVFDSTMEYTPLEIDTNVLQLITSNNFSTAQIAKALRVPSY
                     KLGVNSPNQSVAQLMEDYVTNDLPFYFDAITSELGLKTLNDKDRRLYRIEFDTRSVTG
                     RNVDEIVKLVNNQILTPNQGLVELGKQKSTDPNMDRYQSSLNYVFLDKKEEYQDKVGI
                     KGKGGEVNAKEDKS"
     gene            6280..6945
                     /locus_tag="ACF4ZO_001523"
     CDS             6280..6945
                     /locus_tag="ACF4ZO_001523"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001126086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0046797 - viral procapsid maturation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="head maturation protease, ClpP-related"
                     /protein_id="HFD5487046.1"
                     /translation="MPKRINLKGPLIANNSQEVYDYYGMEAASAKSIIEKLPEDNSDI
                     ILEVNSNGGLVTVGSEIYTALRNYKGKVTAEITGMAASAASVAVMGVDKVVMSPTAQM
                     MVHKASFNWVAGNSDDLDKASNALKSSDKAIVNAYVAKTGLPEDEIMELMKNETFMSA
                     QDAVEKGFADEVMSFEAVASIDNQMLPQAVIDDYYANRSKRKQEISNMLLEIEKEEIL
                     QGL"
     gene            6971..8155
                     /locus_tag="ACF4ZO_001524"
     CDS             6971..8155
                     /locus_tag="ACF4ZO_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HFD5487047.1"
                     /translation="MFEEKIKEIKATIADLNNTIVTKTAQVKNALESDDLEAARSIKA
                     EVEQAKANLAEAENDLKLYESSAEKGGAENTGGKEVPQETKTYRESVNEFIRSKGTIT
                     NEALRFEGKDEVLIPLNQTTPVDPKTDGVKKTDAKPVSSEEILYTPAREVKTVVDLKQ
                     FTSIHPAKKASGKWPVLQRATEKMISVEELEKNPKLAKPKFKDVEWKVETYRGAIPLS
                     QESIDDADVDLVGIVAETIGQMKVNTTNDAIATVLKKFEAKTVKNLDEIKKLLNVELD
                     PAYNVSFIVSQSFYQTMDTLKDKNGRYLLQDSITSVSGKVFLGKPVFVLADEVLGKDT
                     AFIGDFKRGVLFADRKDLGLRWVDNDIYGQFLQAVLRFGVAKVDDKAGYYVTFKPEQL
                     PL"
     gene            8169..8297
                     /locus_tag="ACF4ZO_001525"
     CDS             8169..8297
                     /locus_tag="ACF4ZO_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5487048.1"
                     /translation="MAKPTSKSTVEDIKRYLTSKGIDFSGKTLKSDLLALAGVQEV"
     gene            8300..8602
                     /locus_tag="ACF4ZO_001526"
     CDS             8300..8602
                     /locus_tag="ACF4ZO_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="head-tail connector protein"
                     /protein_id="HFD5487049.1"
                     /translation="MAVSKELLDSVKLYCKIDFDFEDDIIKEMIESAQEQICFAIEEG
                     STADTFKESAKFALAVKKQVKEEYDHRGLFADSFRYPLANGVLNIIHQLRLRGDDS"
     gene            8599..8946
                     /locus_tag="ACF4ZO_001527"
     CDS             8599..8946
                     /locus_tag="ACF4ZO_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HFD5487050.1"
                     /translation="MITRKMNVRITIFSQSGGQNEDGEVVSAIRKDVYTCWAEVLKTQ
                     LRDFNYQSKFQNASNLPTNKDTKVFLIRYNPKLSIDNTMFVEFNKRIYKIDKIESDES
                     GKDITMISGVSMS"
     gene            8943..9320
                     /locus_tag="ACF4ZO_001528"
     CDS             8943..9320
                     /locus_tag="ACF4ZO_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97-gp10 family putative phage morphogenesis
                     protein"
                     /protein_id="HFD5487051.1"
                     /translation="MTKGLDEILANLTKLEVKAPKTAKAAVTEVAEEFEKALKANTPV
                     YEIETDERLQEDTVISGFKGANAGIVSKEIGYGKATGWRAHYPNDGTIYQRGQDFKEK
                     TINQMTPKAKQIYAEKVKEGLGL"
     gene            9317..9742
                     /locus_tag="ACF4ZO_001529"
     CDS             9317..9742
                     /locus_tag="ACF4ZO_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5487052.1"
                     /translation="MTAETAAYKLLSNDKTLNELLDRLRGGTFKNGFKQGIFTYDIPD
                     NPVDLRKVELAPFMRIKTTLDGPTDYADDEILCNEQRITINFWCKTASEADQISKCID
                     DILKKGGFERYTANEKPRYKDSDIDLLMNVRKYRYFDFY"
     gene            9759..10367
                     /locus_tag="ACF4ZO_001530"
     CDS             9759..10367
                     /locus_tag="ACF4ZO_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="major tail protein"
                     /protein_id="HFD5487053.1"
                     /translation="MGKVKFGLRDFYYGVLDGNDKVTKAESIKHLPGMKSAKLDITNE
                     LVTVPADDGPYVVLSGGISETKLEIELLDLTSDARKDFFGITVEKGVEKYNKNLTPND
                     IVCLFRTGDENGKAIWIALLKGKFNLPGMEAQTKEGAPDPKPDTTTGNFVARGPKEEV
                     LLVGREGNSGFDLNEFLKCVFAGCVDTEIKKIPIAKQAGEVM"
     gene            10420..10747
                     /locus_tag="ACF4ZO_001531"
                     /pseudo
     CDS             10420..10747
                     /locus_tag="ACF4ZO_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411857.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            10777..10944
                     /locus_tag="ACF4ZO_001532"
     CDS             10777..10944
                     /locus_tag="ACF4ZO_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5487054.1"
                     /translation="MWVQSLLKNGYTILDIKKMRLSDIELMVQALEIETVEKEEVIET
                     TLDKAFPFLFG"
     gene            10957..14880
                     /locus_tag="ACF4ZO_001533"
     CDS             10957..14880
                     /locus_tag="ACF4ZO_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HFD5487055.1"
                     /translation="MGNIGDLVATATLDISPFMSNTRNLKTYMKGLDNSLKAVEKSFQ
                     GHGGRIKGLKAVYAETGSALKGYQELLKTQSQKYSYLKKEIGDVNNATAEQKQKLIGA
                     KSAMLETAAQVAELQNRLRALATETSVFTRFGKAVERVGGKMKSFGDSVAGVGAAFTR
                     GVTAPIVTGAGYAIKAAVDYESAFAGVKKTVDETATVSYAKLSQGIRQMAKELPASAV
                     EIAHVAEAAGQLGVKTGDILSFSRTMIDLGESTNLSAEEAATSIAKIANITGLASSEY
                     SRFGSAVVALGNNFATTERDIVAMTNRIAASGKLAGLTNQEMLALATAMSSVGIEAEA
                     GGTAMTQSLSAIERAVASGGNNLNKFAQIANMSSADFARAWKEKPIVALQEFIKGLGQ
                     LDKKGESATKVLDELGLSGIRQSNMLKSLGLASETLGKALDTSNKAWQENTALTNEAN
                     KRYETTESKLKMLKNEINDVAIEFGGPLVDALRNGLEAGKPIIQMAADLAKHFNSLDK
                     EQQQQIIKWGLIAAAAGPALSIFGKGVGIVGSTIQGIGEMSQGLGALSGWLRTFKSGA
                     VAASVGAEAAATSMGGMAGAVALLSNPVTWGVLLGGAAVIGIGLIADSMYKAQKRTEE
                     WGAAVSETEATALSNFKKKVDETNASLQMFEAGAGSVKKVTEAFDDLVGSIEKLAQSK
                     LDKNINLAKKLGLSEETINALKSKTESVVNNVKSMNTQIKAIMEKHNGDMSQLSSAEK
                     ELVLRNQREMIIAQLDLMKFSASEKKALTAALNNELDALNARQLEKVSENTVKMLDKE
                     NSAYKTKKAELKEILKQFGSDTGKLSAEELAARQEVLNRLTELNMQHNLKTKALNDQY
                     LAIQRERVQRLKESGKSQEEIHQGISQMASDMAQKLGVSYDDAYRKLAYYTEKSGETL
                     KVLSRNTANATAEVAAANAQWDSLFTSDNPQQSLNELLSTAEGWNSFEIMVKNADVEP
                     TGRAALVEMLAAGGQWQNMSLEQKKLVVDGQQAMIEIFDSKELLAQWQVLTPEEKVLL
                     AKNLTQEPTMSAQQALDSVKQTVPADVNATDKTAGDTQSAQSKIDNVKQKAPADVKAS
                     DKTRPDVASANRAVNSPKQNSPAVIRAQDNASGVAENVIWSLARIPRSVTTTITTFVR
                     KIFGHEKGTDFHPGGLAVVNDQKGALYRELVTLPTGESFIPTGRNVILPLPRGSKVLK
                     ASRTKQLFPHYANGIGFDDTKIASLTTRLKFVQDKGTVVVNADPQLAELIKVLKDRDD
                     RNVTNNYTLNATNSSSSEDMFSQENMRRLLRELAYYTKGEEGRLA"
     gene            14880..15587
                     /locus_tag="ACF4ZO_001534"
     CDS             14880..15587
                     /locus_tag="ACF4ZO_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="distal tail protein Dit"
                     /protein_id="HFD5487056.1"
                     /translation="MRYIEFNGTKSNDLGLLLERERLIKSTNNDVDLIEVAGRDGVLL
                     KDNGRLKVIEQGFPFSLVGNVTVNQQKISEWLHVKGWHDLALSWDKDYIYRASVVNLF
                     EIDEILKQFGRLKVNFLIHPIKYLKTGKQEVSLVNGSTLQNPGNVQAKPILKIKGIGN
                     GVLTINGFKTGLENVQGELVIDMERHLVYKDVLSAWDNIVRTERHRMPLFDVGQNKIS
                     WTGNFTITAVPNWGVKV"
     gene            15584..>15978
                     /locus_tag="ACF4ZO_001535"
     CDS             15584..>15978
                     /locus_tag="ACF4ZO_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HFD5487057.1"
                     /translation="MIPVLYEAKETKFRTFGLGEIADAYEVKVTRERNGNYSLYIKYP
                     LDGVFASVFKEEMKIKSDAGRRTKWQTFEINRVLRNSKDHIEIFARHISMRTQDIALK
                     PFVNGASVGAESALEIWKKNLVGDDKFDV"
BASE COUNT         5485 a         2648 c         3592 g         4253 t
ORIGIN      
        1 atggaggata gagaatgaca gacatcaaga ttttagatgc ttgttgtgga agtcgcctat
       61 tttggtttga taaaaacgaa cctcacacaa cttttatgga cgtcagacaa gaaaaatttg
      121 agatgcacgg caaaaaaatc aatgtcaacc ctgatgtaat tggtgatttt cgtgatatgc
      181 cttttgaaag taatagcttt aaccttgttg tcttcgaccc accacactta aaatatgttg
      241 gacaaaactc aattatgaaa gcccagtatg gccaacttga taaagaaaac tggaaagaag
      301 atatttcaaa aggtttcgaa gagtgtatga gagttctaaa agtaggagga actttagttt
      361 ttaaatggtc tgattgccag gttaatgtaa gagaagtttt gtcagcaatt ccatttaaac
      421 cgctttttgg tcaacaacgc gggacaactc actggatgac atttgtaaag tttgctgaac
      481 tgacagggaa cgggagatga aaaatgaaca aacaaaactt tgaaaaacta gataaagtta
      541 aggaattact tgacgaacta aaaattccag aatttatggc gccactttta gttggcaatc
      601 agattatgga aattatcaac gacttacata atgaaccaga tcaatttgga gcacaggtgt
      661 tactaccatc gccagacaaa aaatataagt ttgcagtgcg aatttgtcga gaagaaaatt
      721 tagaggattg agttaacgga aatgggggta ggataatggc tgaaaataaa actggaatga
      781 tgactttacc aatcgactat gcaaatagag cattagcaaa agaggaaata cttgatgaac
      841 ttgttgaaag agaaattgta gatgtagatc tgttaataga gcttgcagaa gataatccgt
      901 tttggatgag tgcattgaat tttaagcgag gtacaaaatg aacactaacg aaaaagtaat
      961 cgatactata tgtcacatca gacattacgg tgacagatac gatatgtgcc aagacatgcg
     1021 gacgtgggta gctgagagaa atggattaat ccaggactta ctcaaagcaa aaaaagaaag
     1081 agagggcttt tctccacaaa acaaaaagac gtccacacgg aacgccccct tggttaaatt
     1141 taagcttaaa taaattatac catactggag gctttcatga cgttttttcc tgagattgat
     1201 atccaaaaaa caaaatccaa tgccaagcgt aaattgagag agtatccacg ctggcgaagg
     1261 atagctaatg acgtagatac tcaaaaagtt acagctactt actcctttga gccaaggcaa
     1321 tcacatgggg ttcctagcaa accggttgag agactagcgc taaaccgtgt gtcagcagaa
     1381 caagagctgg atgcgattga gcaagccgtc agtatgatac tagagccaga gagacgcagg
     1441 attttgtatg acaaatactt agcgccttat aaaaaggcag ataaggttat ttatacagaa
     1501 ttgtgtatgt cagagagctt ttactatgat acacttgaca ttgctttgtt agcttttgca
     1561 gagctgtaca gagagggtgt gttgcttgtt gaggaaggag tttttagcta gtttttatac
     1621 agtaataaga tagtttatac atatttttac atgttattat agtattatca aaataacaag
     1681 aagagataac cttttaatca ctgactattt tatttagtcg ccaactttaa ctacgatcaa
     1741 acttgttatt ttatggtatg tgggacgtgc aggttcgatt ccgactgttc ctgtgaaaag
     1801 ctctaagaag cctacgggcc ttaggagcga tgaagttaga gaattgcata tcgctctaac
     1861 tcaatatgca ctagtcatca caccgtggtg gctttttatt atggaggtca gggtatgagg
     1921 ccacagaagt taactatcgc aggtggtaga cgtacaacag ttgactacga tgacagatca
     1981 gcagagtatc gtgactataa tcgtaatcgc tggaagtacg ataaacaagt caaacagttt
     2041 tataactcaa gaatatggag agagacaagt aagcaagtat tacttcagaa cgattatatc
     2101 tgtgctatgt gtggtggcga agcgactatg actgaccaca ttgtatcagt caaacaagat
     2161 tggaacaaaa gattagattt gaataacttg caagcaagct gtaaagcatg taatgatagc
     2221 aaagcgataa gggaaagacg taaaaacaat tactagaaaa acgggtgtaa aaattaacaa
     2281 tagtactggc tataatattc ggaaactacc cccttcattt ttaaacgggg atatattgtt
     2341 cggaaactta agaacgcgcc cttttccgtg caaaaaattc cctttttgaa atttttaaaa
     2401 ctgtaaagtt cgtgtaaagg aggtcttatg ggaagaaatt taaagctagt cgaaacgaca
     2461 aaaaagcatc ttacaaaaga agaaaaaata gtgcgagaaa ccgcgcaaaa taaggcgtct
     2521 gacggtttta aaaagttgca aaagacacct cctgaacact ttaataatgt agctaagtac
     2581 gagtatagga gaatcataga agacctccaa aacctacccc taagaaatct cgatagaggg
     2641 ctattagagt tatattgcac atggtatgct atctacaaag aaacaagtag aaaactagat
     2701 gaggttggtt attttacgaa tgatccagac aagggcatta ttcctagtcc gcttatttta
     2761 acactagaaa aagccacagc gaatattaga agtagcgcaa gtcagcttgg tttgactgtg
     2821 gatagtcgga tgaaaatgtt tattcctaaa gaagaggaaa agcctaagag tatttttgat
     2881 aaatttggag gataaaaaga aagggggtca tgacaataga atacgattat tcagcaattg
     2941 acgacttcta taaagatgac gctttttatt atgcaaaaat ggtcgttgat gaacagataa
     3001 aatcaagtaa aaaagttttt aaggcatgct tgagacattt gaatgacctc aaaaaaatag
     3061 atggtgataa ttttaaattc atctatttac cagaaaaagc agctgatcca attaacttta
     3121 ttgagatttt gccagatgta aaaacgggga aaccttaccc gttggcgatg ttccagaagt
     3181 ttattattgg gaatttatat ggatggcgaa agaaaacaga tcattccttg agacgtttta
     3241 gaaaagctat gatttctgtt gctcgtaaaa acggtaaaac aattctgata gctggtatct
     3301 tgctttatga atttttgttt ggccataacc catctatgag cagacaattg ttttgtactg
     3361 caaatgatag aacgcaggct aaaatcgctt gggatatggc aaagaagcag ttatcatctc
     3421 tcagagcgaa ggacgctgat gtcagaaagg ctacaaaaat tgtccgtgat gagcttaaaa
     3481 acttacatga cgaatcatat atcagagcac ttagtcgaga tactggagct gtagatggat
     3541 ttgagcccta tgttggcgtt ttggatgagt ttgcagcatc gaagacaaat gaaatgttgg
     3601 agctcttaga atctggtcaa ggtcagcttg ataacccgtt tatcttgatt atttcgacgg
     3661 cagggatgga tttgaatgtc cctatgcaca caattgagta tccatacatc actaaaatac
     3721 tagacggaga aatcacagac gagggttatt ttggatatgt tgcagaacag gacaacgaag
     3781 aggaaattaa agacgaatca aactggataa aatcaaatcc aatccttgag gttgaagctt
     3841 tacatgataa gctaatggat tacctgagaa cgcgtcgtag agtgtccctt gaaactggtg
     3901 aaatcaataa agtattaatc aaaaacttta acatgtggcg tcagtctagt gaggaatctt
     3961 acatcgataa aacgacttgg gaacttgctc ggattgataa gccagatact aataagcgga
     4021 gagtttggtt aggtgttgac gttggtcgtg ttagcgactt atttgctatc acaccagttg
     4081 ttatgatgga tgatttttgg tatatcgaca gcttttcttt tgtggctacc aaatatggtt
     4141 taactgctaa agaaaagcgg gatggcgtat cttatagcaa ccttgaatgc caaggttatt
     4201 gcgagataac caccctagaa agtggtgtca tcgatgatga acgtgtactc gaaaaaattg
     4261 aagagatggt ctactcaaac gactgggaaa ttaatggaat ttgttttgac ccttatcaat
     4321 ttggaacatt acttacaatg attgaaaaaa ggcatccaga gtggcctctg attgaggtta
     4381 gtcaaacgac aatggttttg aacatgccga caaaacaatt tcgtgacgac ctcaaaaaag
     4441 gcaaaataaa gcactctggt aaccctttgc taaccatggc tgttaacaat gcttatatta
     4501 aaactgataa taatggtatg aggattgata agaataagaa tagcaataag attgacccgc
     4561 ttgatgctgc tcttgatggc tacgctgttt gttacttaga accgttcgat ggttctggct
     4621 actggacaaa tgaaaaaata ataggaggag aatcgctgtt ttgattgatt ttattttaaa
     4681 aaacatacac acattaatct tgttagctgg actaggttta ttgatgtatg ggttgttttt
     4741 gtttggtgat aaagtcggtt ttattgccag tggtcttatt ttaattgttt tagctatcta
     4801 tgtagatagc gtaggaggaa aacgtgaata aacgcattaa gaaaaaacga aaattggaaa
     4861 cagctattgt gttgctaatt aaagaagtcg ccgaattacg atccatcgtg tcagcaaatg
     4921 ccaaagctac aaataacgag cttgcagcag ttaaatcagc gatactagac aatcaagtag
     4981 ccatcaagtc aattggtgat gaggttggtc acatcaagca aaattataag cgcaagtggc
     5041 ggaaatagat gttaatggtt tagaaaggag gtgagaaatc gatgagtttt tttcaacctt
     5101 tgggcagttc aaaggtgtcc tatgatgact atatatcatc tgttttagct ggtgatgtct
     5161 cccaaaaata cttaggagta tcggctttga agaatagcga tattttaaca gcgacgtcta
     5221 ttatagctgg ggatattgct agatttccgc ttgttaaaaa ggacgttaat ggagatatta
     5281 tccacgatga ggatattaat tatcttttaa atgttaaatc tacaaaaaat gcgagcgcca
     5341 ggacatggaa atttgctatg gcagtaaatg ccattttgac tggtaattca ttttcgcgta
     5401 ttttgagaaa tccaaagact aatcaagctt tgcaattcca attttacagg ccgtcagaaa
     5461 cgactgttga ggaaacagat aatcacgaaa tagtttatac gtttactgat actttaacag
     5521 cgaaacaggt caaatgcttt gctcatgatg ttgtacactg gaagtttttt agccacgaca
     5581 caatccttgg caggtctccg ctactgtctt taggagatga gattgatttg caaacaggtg
     5641 gtatcaatac cttaattaaa ttctttaaag atggattttc tagcggtatc ttaaccatga
     5701 aaggcgctca attaagcgga gacgcacggc agcgagcacg tcaagagttt gagaaaatgc
     5761 gcgagggttc ggtcggtggc agtccattgg tgtttgatag taccatggaa tacacgccgc
     5821 ttgaaattga tactaacgta ttgcagttaa tcactagtaa caatttttca acggcgcaaa
     5881 tcgcaaaagc tttgcgggtt cccagctaca agcttggtgt taatagccct aatcaatccg
     5941 tagctcaact gatggaggac tatgtcacaa acgacttgcc tttttatttt gacgcgatta
     6001 caagcgaatt aggtcttaaa acgttaaatg ataaagatag acgtctctat cgtattgaat
     6061 ttgatacacg tagcgttaca ggtcgtaatg ttgatgagat tgtcaaattg gttaataacc
     6121 aaattttgac gcctaaccaa ggcctcgtgg agcttggtaa gcaaaaatca acagatccaa
     6181 acatggatag gtaccagtct agtctaaact acgtcttttt agacaaaaaa gaagaatatc
     6241 aagacaaggt tggtatcaaa gggaaaggag gtgaggtaaa tgccaaagag gataaatctt
     6301 aaagggccgc taattgcaaa taactctcaa gaagtttacg actattacgg aatggaagct
     6361 gctagcgcta aaagcattat cgagaaacta cccgaagaca atagcgacat tattttggaa
     6421 gttaattcaa atggtggtct tgttacagta gggagtgaaa tctataccgc tttgcgaaat
     6481 tacaaaggta aagtgacagc tgaaattaca ggtatggctg ctagtgcggc atccgttgca
     6541 gttatgggag tagataaagt tgtcatgagt ccaacagcac agatgatggt acacaaggca
     6601 tcgtttaatt gggtagctgg taatagcgat gacttagata aggcttctaa tgctttgaaa
     6661 tcaagcgata aagctattgt taatgcttac gttgcgaaaa caggcttacc agaagacgaa
     6721 atcatggaac taatgaaaaa tgaaaccttt atgtcggctc aagacgctgt tgaaaaaggt
     6781 tttgctgatg aagtgatgtc ttttgaagct gttgccagca tcgataacca aatgttgcca
     6841 caagctgtta ttgacgacta ttacgcaaac agaagtaagc gcaagcaaga gattagcaac
     6901 atgttgctag aaattgaaaa agaagaaatt ttacaagggc tatgagctct ttttttattg
     6961 gaggaaatta atgtttgaag aaaaaattaa agaaatcaaa gcaacaattg ctgacttaaa
     7021 caacacgatt gttactaaga cagcgcaagt caaaaatgct ttggaatcag atgatcttga
     7081 agctgctcgc tcaattaaag cagaagttga acaagctaaa gcgaacctag cagaagcaga
     7141 aaacgacttg aagttatatg aatcaagcgc cgaaaaagga ggagcagaaa atactggagg
     7201 aaaagaagtg ccacaagaaa ctaaaacata ccgcgaaagc gttaacgaat ttattcgttc
     7261 aaaaggaaca ataactaacg aagctttgcg ttttgaagga aaagacgagg ttcttattcc
     7321 acttaaccaa acaactcctg tagaccctaa aacagacggc gtgaagaaaa cagacgctaa
     7381 accagtgtca agcgaagaaa tcttatacac accagctcgt gaggttaaaa cagtcgttga
     7441 tttgaagcaa tttactagca ttcacccagc taaaaaagca tcaggtaaat ggccagtgtt
     7501 acaacgtgcg actgaaaaaa tgattagcgt tgaagaattg gaaaaaaatc caaagcttgc
     7561 taaaccaaaa tttaaagacg tagagtggaa agtcgagact taccgcggag ctatcccgtt
     7621 gtctcaagag tcaattgacg atgcagatgt tgatttagtt ggaattgttg ccgagacaat
     7681 cggtcaaatg aaagttaata caacaaacga cgctatcgca acagttctca aaaaatttga
     7741 agctaagaca gtaaaaaact tggatgaaat caagaagctt ctcaacgttg aattagatcc
     7801 tgcttacaat gtgtcattta ttgtatctca aagcttttat caaacaatgg atacactaaa
     7861 agataagaat ggtcgttatc tactccaaga ctcaatcact tctgtttctg ggaaagtatt
     7921 ccttggaaaa cctgtttttg tactagctga tgaagtttta ggtaaagaca cagcctttat
     7981 tggagatttt aagcgtggtg tattattcgc agatcgcaaa gacttaggtt tgcgttgggt
     8041 cgataatgac atttacggtc aattcttgca agcagtactt cgatttggtg tcgctaaggt
     8101 agatgacaaa gctggctact atgtgacatt caagccagaa caattgccct tataaggcca
     8161 ctgaagaagt ggcgaaacca actagtaaga gcactgtcga ggacattaag cgctatttaa
     8221 caagcaaggg aattgacttt agtggcaaga cattgaaatc agatttactt gcactagcag
     8281 gcgttcaaga ggtatagcta tggctgtatc gaaagagtta ttagacagtg taaaactcta
     8341 ttgtaaaatt gactttgatt ttgaggatga catcattaaa gaaatgattg aatctgctca
     8401 ggaacaaatt tgttttgcga tagaagaagg ctcaaccgca gacacgttta aggaaagcgc
     8461 taaatttgct ttagcagtca aaaaacaagt caaggaagag tatgatcatc gcggtttgtt
     8521 tgcggatagt tttcgctatc cgttggcaaa tggcgtttta aacatcatcc atcaactacg
     8581 attgcggggt gatgattcat gattacacgc aagatgaacg tcaggataac gatttttagc
     8641 caatcaggtg ggcaaaatga agatggtgaa gtagtatctg ctatcagaaa agacgtctat
     8701 acatgttggg cagaagtgct gaaaactcaa ttaagagact ttaattacca atcaaagttt
     8761 caaaacgcta gcaatttgcc aacaaataag gatacaaagg tctttttgat taggtataat
     8821 cctaagttat ctatagataa cacgatgttt gttgaattca acaagcgcat ctataagata
     8881 gataaaatcg aatctgacga atctggcaaa gatatcacca tgataagtgg agtaagcatg
     8941 tcatgacaaa gggtttagat gaaatattag ctaatctgac aaagcttgaa gtaaaagccc
     9001 caaaaaccgc aaaagcagca gtaactgaag ttgccgaaga atttgaaaaa gcacttaaag
     9061 caaatacccc tgtttacgag attgaaacag acgaaaggct gcaagaagat actgttatca
     9121 gtggttttaa aggagctaat gccggaattg tatccaagga aattggttat ggcaaagcta
     9181 ccggttggcg cgctcattat cccaatgatg ggacgattta tcaacgtggc caagacttta
     9241 aggaaaaaac aatcaatcag atgacaccaa aagctaagca gatttacgct gaaaaagtga
     9301 aggagggact agggctttga ctgctgaaac agcagcttat aaattattaa gcaacgataa
     9361 gacgctaaat gagctgttgg ataggctcag aggcggtact tttaaaaatg gatttaaaca
     9421 aggaatattt acatatgata tcccagataa tccagttgac ttgcgaaagg tagaactagc
     9481 gccatttatg cgtatcaaaa caacgttaga tggtcctacc gattatgctg atgacgagat
     9541 actttgtaat gagcaacgta tcaccatcaa tttttggtgc aaaacagctt cagaagctga
     9601 ccaaattagc aaatgtatag atgatatttt aaaaaaaggc ggttttgaaa gatacaccgc
     9661 aaacgaaaaa ccaaggtata aagatagcga tattgactta ctcatgaatg taaggaaata
     9721 ccgctatttt gatttttatt aaaaagaaag aggacaaaat gggaaaagta aaatttggac
     9781 tacgtgattt ttactatgga gtactagacg gaaatgacaa ggttacaaaa gcagagagta
     9841 taaagcattt gccgggaatg aaatccgcaa aacttgatat taccaatgaa ttggtcactg
     9901 tgccagcaga cgatggacct tacgttgtat tatcaggtgg aatcagcgag acaaaacttg
     9961 aaatcgagtt gttagattta acatcagatg cacgcaaaga tttctttgga atcacagtag
    10021 aaaaaggtgt tgagaagtac aacaaaaacc taacgccaaa tgacattgtt tgtttattta
    10081 ggactggcga tgaaaacggt aaggcgattt ggattgcgtt gcttaaaggg aaatttaatc
    10141 ttccgggaat ggaggcacaa acaaaagaag gcgcacctga tccgaaacca gatactacaa
    10201 cgggtaactt tgttgcccgc ggaccaaaag aagaagtgct tttagttgga cgcgagggta
    10261 atagcggttt tgatttgaat gaatttttaa aatgtgtatt tgccggctgc gttgatacag
    10321 aaatcaaaaa aataccaatt gcgaaacaag caggtgaggt tatgtaattt ttaaggtcgc
    10381 agcttaaatg cgacctttta tttttgataa ggagtagata tgtacgaaat taccttaaaa
    10441 aaaaggcggt gttgataagg aatttaaaaa agacttcatc aacgtcgaag ataatttgtt
    10501 ggctgttgag catcaagtta gacaaagcgc tgtgtttagc gatgagaaaa gacgcttaga
    10561 ttctaaagcg catagaaaac ttaacgaatc ttacttgcaa atgtttgttg atatgtacgc
    10621 aggtcaattt acagtcgatg atcttaagct atccgacatg agtgttttag acacgcttaa
    10681 cgacctttat attgccgcgc tcggaggaga agaagaggaa ggtgaaaccg aaaaaaagga
    10741 acaataaccc ctcaagaagc caaagataat ttgctgatgt gggtacaaag tctattaaag
    10801 aatggctata cgattttaga tattaaaaaa atgcgcttat cagacatcga attgatggta
    10861 caagcgctag aaattgaaac tgtcgaaaaa gaagaagtga ttgaaaccac cttggataag
    10921 gcattcccat tccttttcgg ctagaaagga gactaaatgg ggaatatagg tgatttagta
    10981 gcaacagcta cattagacat atcacccttt atgtcaaaca caagaaacct aaaaacctac
    11041 atgaaaggct tagataactc gttaaaagca gttgaaaaga gctttcaagg gcatggcggg
    11101 cgaattaaag gtcttaaagc ggtctatgct gaaacaggta gtgcattaaa aggttaccaa
    11161 gaattactaa aaactcagtc acaaaaatat agctacctaa aaaaagagat aggtgatgtt
    11221 aataacgcta ctgctgagca aaaacaaaaa ttaattggcg ctaaatcagc catgctagaa
    11281 acagcagcgc aagtggcgga attgcaaaac agattacgag ctttagctac agagaccagt
    11341 gtctttactc gctttggtaa agccgttgaa agagttggcg gcaagatgaa gtcgtttggc
    11401 gattcggttg ctggagttgg tgctgcattt acaagaggag ttacagctcc gatagttaca
    11461 ggagctggtt atgctattaa agctgctgtc gattatgaat ctgcttttgc cggtgtcaag
    11521 aaaaccgtgg atgaaacggc gacggtatcc tatgctaagt tgtcgcaagg cattagacaa
    11581 atggccaaag agttgccagc cagtgctgtt gaaatcgctc acgttgcaga agcagcaggt
    11641 caattaggag ttaagacagg agatattctt agtttctctc gtacaatgat tgatttagga
    11701 gaatctacca atttatccgc agaagaagcg gcgacgtcta ttgctaaaat tgcaaacatt
    11761 acaggtctgg cttcatcgga gtattctcgc tttggtagtg ctgttgtcgc gttgggtaat
    11821 aacttcgcaa caactgaacg agacatcgta gcgatgacaa accgtatcgc cgcgtctggt
    11881 aagcttgcag gcttaacaaa ccaagaaatg cttgccttag caactgctat gtcaagcgtt
    11941 ggtatcgagg cggaagctgg tggtacagca atgactcaat cattatcagc tattgaacgt
    12001 gcagtcgcat ctggaggcaa taatttaaat aaatttgctc agatagctaa catgtcctca
    12061 gccgattttg ctagagcgtg gaaagaaaag ccaattgtcg cattgcaaga gtttattaag
    12121 gggcttggtc aacttgataa aaaaggcgaa agtgccacaa aagtacttga tgagttagga
    12181 ttaagcggta ttcgccagtc taacatgttg aaatcattag gtttagcatc tgaaacatta
    12241 ggcaaggctc tagacacctc aaataaagct tggcaagaaa acacagcatt gactaacgaa
    12301 gctaacaaac gttacgagac aacagagtct aagctgaaaa tgcttaaaaa cgaaatcaac
    12361 gatgtagcta ttgaatttgg cggaccatta gtcgacgcat tgagaaatgg gcttgaagca
    12421 gggaagccaa tcatccaaat ggcggctgac ttagctaaac attttaactc gctcgacaaa
    12481 gagcaacaac agcaaattat caagtgggga cttattgcag ccgccgctgg gccagcttta
    12541 tctatctttg gtaaaggcgt tggtattgtt ggtagcacta ttcaaggtat cggggaaatg
    12601 agccaaggct taggggcttt gtctgggtgg ttaaggacat ttaaatctgg agcagttgcg
    12661 gctagtgttg gcgctgaagc tgcagcaacc tctatggggg gcatggctgg agcggttgcc
    12721 ttattaagta acccagttac atggggtgtt ttgctaggtg gcgcagctgt tattggtatt
    12781 ggtttaattg ctgatagcat gtataaagcc caaaaacgca cggaagagtg gggagccgct
    12841 gtttccgaga cagaagcaac tgcactaagc aactttaaga aaaaagttga cgaaactaac
    12901 gcttctttgc aaatgttcga ggcaggcgca ggtagcgtta agaaagtgac tgaagccttt
    12961 gatgacttgg tcggaagtat tgaaaagtta gctcaatcaa aattagataa gaatataaac
    13021 ttagctaaaa aattaggatt gtcagaagaa accataaatg ctttgaaatc caaaactgaa
    13081 tcagtagtta acaatgtcaa aagcatgaat acccagatta aagcaatcat ggagaagcac
    13141 aatggtgaca tgagccagtt gtcaagcgct gaaaaagaac ttgttttgcg aaatcagaga
    13201 gaaatgatta ttgctcaact tgatttaatg aagttttctg catcagaaaa gaaagcttta
    13261 acagcagctt tgaataacga gttagatgcg ctaaatgcaa ggcagttgga aaaagtgtct
    13321 gaaaataccg tcaagatgct tgataaagaa aactctgcat ataaaacaaa aaaagcagag
    13381 ttaaaagaga ttttgaagca atttggcagc gacactggta aattgagcgc tgaagaattg
    13441 gctgctagac aggaagtttt gaatagactt acagaactta atatgcagca caacctaaaa
    13501 accaaagctt tgaacgatca gtaccttgct atccagaggg agcgagtcca acggttaaaa
    13561 gaatctggta aaagtcaaga ggaaatccat caaggaataa gccaaatggc atcagatatg
    13621 gctcagaagt taggagtcag ttatgatgac gcttatcgca aattggctta ctataccgaa
    13681 aaatctggtg aaacgttgaa agttttatca cgtaatactg ctaatgccac tgcagaggta
    13741 gcagcagcaa atgctcaatg ggatagtttg tttacaagtg ataatccaca acaaagttta
    13801 aatgaattgt tgtcgacggc agaaggttgg aatagctttg aaatcatggt taagaatgcc
    13861 gacgttgaac cgacaggtag agctgcactt gttgaaatgc tagcagctgg cggacagtgg
    13921 caaaacatgt ctcttgagca gaaaaaatta gttgttgatg ggcaacaggc catgattgaa
    13981 atttttgata gcaaagagtt gttagcgcaa tggcaagtgt tgacaccaga agaaaaagtc
    14041 ttactagcga aaaacttaac acaagaacca actatgtccg ctcaacaagc tcttgatagc
    14101 gttaaacaaa cagtacctgc tgatgtgaat gctacggata aaacagcagg tgatactcag
    14161 tcggcgcaaa gtaagattga taatgtcaag cagaaagcgc cagccgatgt gaaggcatcg
    14221 gataagacta gaccagatgt tgcaagcgcc aatagggcag tcaatagtcc taaacaaaat
    14281 agtccagctg ttattagagc acaagataac gcaagcggcg ttgcagaaaa tgttatatgg
    14341 tcactggcta gaatcccaag aagtgttaca acaaccatta caacgtttgt ccgtaagatt
    14401 ttcggacacg aaaaagggac tgatttccac cctggcgggt tagctgtggt caatgaccaa
    14461 aaaggggcgc tatatagaga gttagttacc ttaccgactg gagaatcatt tatcccaacc
    14521 ggtcgaaacg ttatcctccc tctaccgaga gggtcaaaag ttttaaaggc cagccgaaca
    14581 aaacagttat tcccgcacta tgcaaatgga ataggttttg atgatacaaa aatcgctagc
    14641 ttaacaactc gtcttaaatt tgtgcaagat aaaggaactg tagtcgttaa cgctgatcca
    14701 caacttgccg agttgattaa ggtgcttaaa gacagagatg acagaaatgt cacaaacaac
    14761 tatacactaa acgctactaa tagcagtagt tcagaagata tgtttagtca agaaaacatg
    14821 agacggctac tcagagaatt agcttactac acaaaaggtg aagaagggag gttagcttag
    14881 tgagatacat tgagtttaac ggaactaaaa gcaatgattt aggtttgttg ctagaacgcg
    14941 agcggttaat taagtcgaca aataatgacg ttgatttaat cgaagtagct ggacgtgacg
    15001 gtgtactctt aaaagacaat ggtcgtttaa aagttatcga acaaggcttc cctttttcct
    15061 tggtcggtaa tgtgactgtt aatcagcaaa aaataagcga gtggttgcac gtcaaaggtt
    15121 ggcatgactt agctttgtct tgggacaagg actatatcta tcgggctagt gttgtcaatc
    15181 tttttgaaat agacgagata cttaagcaat ttggtagatt aaaggttaat ttcttaatcc
    15241 accctatcaa atacttaaaa acgggtaagc aagaggtgtc tctcgttaat ggtagtactc
    15301 tacaaaatcc cggcaatgtt caggctaaac ctatcttaaa aatcaaaggt ataggcaatg
    15361 gggttttaac cattaatggc tttaagacag ggctggaaaa tgtgcaagga gaactcgtca
    15421 tagatatgga gagacatctg gtctataaag atgtcttgtc ggcttgggat aatatcgtgc
    15481 ggacagagcg ccaccgtatg cctttatttg acgttggtca aaacaaaatc tcgtggactg
    15541 gtaattttac catcaccgca gtaccaaact ggggggttaa agtatgatac cagttttgta
    15601 tgaggctaag gaaaccaagt ttaggacttt tggtctcggt gagattgcgg atgcttatga
    15661 ggttaaagtc actcgtgagc gtaatggtaa ttactcgcta tatatcaaat atccactaga
    15721 tggtgtcttt gcctcagttt ttaaagagga aatgaagatt aagtctgacg ctggtcgtag
    15781 aaccaaatgg cagacttttg agattaatag ggtactacga aatagtaaag accacatcga
    15841 gatttttgcg cgtcatatct ctatgcgcac acaggatatt gctttaaaac cgtttgtaaa
    15901 cggtgcgagc gtaggagccg aatcagcttt agaaatctgg aagaaaaacc ttgtcggtga
    15961 tgataagttt gacgttaa
//
LOCUS       DAXMQE010000038        15933 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.038, whole genome shotgun sequence.
ACCESSION   DAXMQE010000038 DAXMQE010000000
VERSION     DAXMQE010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15933)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15933)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15933
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.038"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            109..180
                     /locus_tag="ACF4ZO_001536"
     tRNA            109..180
                     /locus_tag="ACF4ZO_001536"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:142..144,aa:Glu,seq:ttc)
     gene            214..287
                     /locus_tag="ACF4ZO_001537"
     tRNA            214..287
                     /locus_tag="ACF4ZO_001537"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:248..250,aa:Asn,seq:gtt)
     gene            complement(784..3360)
                     /locus_tag="ACF4ZO_001538"
     CDS             complement(784..3360)
                     /locus_tag="ACF4ZO_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HFD5487058.1"
                     /translation="MKNNNKWIIAGLASFLFPLSIIFIILLSMGIYYNSDKTILASDA
                     FHQYVIFAQNFRNIMHGSDSFFYTFTSGLGINFYALMCYYLGSFFSPLLFFFNLASMP
                     DAIYLFTLIKFGLIGLAACYSFHRLYPKISAFLMISISVFYSLMSFLTSQMELNSWLD
                     VFILLPLVVLGLNKLITENKTRTYYLSISLLFIQNYYFGYMIALFCILYTLVCLLRLN
                     DFNKMFIAFVRFTAVSICAALTSALVILPTYLDLSTYGENLSPVKQLVTNNAWFLDIP
                     AKLSIGVYDTTKFNALPMIYVGLFPLMLSVIYFTLESIPLKIKLANACLLTFIIISFY
                     LQPLDLFWQGMHSPNMFLHRYAWSFSIVILLLACETLSRLKEVTQIKAGFAFIFLIIL
                     TSLPYSFSQQYNFLPLTLFLLSVFLLLGYTISLFSFRNSQIPSTFISAFILIFSLLES
                     GLNTYYQLQGINKEWGFPSRQIYNSQLKDINNLVNSVSKNSQPFFRMERLLPQTGNDS
                     MKFNYYGISQFSSVRNRLSSSLLDRLGFQSKGTNLNLRYQNNTIIMDSLLGIKYNLSE
                     GPLNKFGFTKLKTSGNTTLYQNHYSSPLAILTRNVYKDVNLNVNTLDNQTKLLNQLSG
                     KSLTYFNLQPAQLISGANQFNGQISAQASDYQNSVTLNYQINIPKHSQLYVSIPNIIF
                     SNPDAKEVRIQTDNHNFIYTTDNAYSFFDLGYFADAKVATFSFVFPKDKQISFKEPHF
                     YSLSIESYLEAMNSIKQKNVHTYAKSNTVITDYNSKTKGSLIFTLPYDKGWSAQKDGK
                     NLPVKKAQGGFLSVTIPKGKGRVILTFIPNGFKLGLSLSCVGIIAYMLLYKYIDIKSK
                     LL"
     gene            complement(3443..5062)
                     /locus_tag="ACF4ZO_001539"
     CDS             complement(3443..5062)
                     /locus_tag="ACF4ZO_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFD5487059.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTAGNTYGLIGANGAGKSTFL
                     KILAGDIEPSTGHISLGPDERLSVLRQNHFDYEEERAIDVVIMGNEQLYNIMKEKDAI
                     YMKADFSEEDGVRAAELEGIFAELGGWEAESEASQLLQNLNIPEDLHYQNMSELANGD
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSISWLEDFLIDFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLFVGNYDFWKQSSELAARLQADRNAKAEEKIKELQEFVARFSANA
                     SKSKQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREMGNDFLTVENLSVTIDGEKI
                     IDNISFILRPGDKAAIIGQNDIQTTALMRALADDIDYEGTIKWGVTTSRSYLPKDNSK
                     DFATEESILEWLRQFASKGEDDDTFLRGFLGRMLFSGDEVKKSVNVLSGGEKVRVMLS
                     KLMLLKSNVLILDDPTNHLDLESISSLNDGIKDFKESVIFASHDHEFIQTIANHIVVI
                     SKNGVIDRIDETYDEFLDNPEVQARVAELWK"
     gene            complement(5141..6013)
                     /locus_tag="ACF4ZO_001540"
     CDS             complement(5141..6013)
                     /locus_tag="ACF4ZO_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFD5487060.1"
                     /translation="MKKRGIDLLLVTIGSFITAIGFNTMFVDNHIASGGMVGIAVVIK
                     ALFGISPSLFLMASNIPLLLMCYFFLGKQNFIKTLYGSWIYPIAIRSTNSLPTLTHNQ
                     LLAAIFGGIICGIGLGMVFWGNSSTGGTGILTQILHKYSPLSLGVAMTIVDGISVLMG
                     FIALSADDVMYSTIGLFVIGYVISVMENGFDSSKNVMIISKDYQAIREYITTVMDRGV
                     TKLPIRGGYTTSDKIMLMAIVSSHELPTLQEKILEIDDTAFIVVMPAAQVMGRGFSLT
                     KQYKREDKDVLLPM"
     misc_binding    6136..6377
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            6432..7454
                     /gene="trpS"
                     /locus_tag="ACF4ZO_001541"
     CDS             6432..7454
                     /gene="trpS"
                     /locus_tag="ACF4ZO_001541"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004830 - tryptophan-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006436 - tryptophanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HFD5487061.1"
                     /translation="MTKPIILTGDRPTGKLHLGHYVGSLKNRVFLQNENKYKMFVFLA
                     DQQALTDHAKESELIQESIGNVALDYLSVGLDPKQSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEIAQKGFGESIPSGFLVYPVSQAADITAFKANLVPVGNDQKPMIE
                     QTREIVRSFNHTYHTDCLVEPEGIYPENEKAGRLPGLDGNAKMSKSLGNGIYLSDDAD
                     TVRKKVMSMYTDPNHIKIEDPGQIEGNMVFHYLDIFARKEDQADIEAMKEHYQRGGLG
                     DVKTKRYLLDILERELAPIRERRLEYAKDMGEVFRMLQEGSQKARTVAAKTLSEVKSA
                     MGINYF"
     gene            7762..9243
                     /gene="guaB"
                     /locus_tag="ACF4ZO_001542"
     CDS             7762..9243
                     /gene="guaB"
                     /locus_tag="ACF4ZO_001542"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003938 - IMP dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HFD5487062.1"
                     /translation="MSNWDTKFLKKGYTFDDVLLIPAESHVLPNEVDLKTKLADNLTL
                     NIPIITAAMDTVTGSKMAIAIARAGGLGVIHKNMSITEQAEEVRKVKRSENGVIIDPF
                     FLTPEHKVSEAEELMQRYRISGVPIVETLANRKLVGIITNRDMRFISDYNAPISEHMT
                     SEHLVTAAVGTDLETAERILHEHRIEKLPLVDNSGRLSGLITIKDIEKVIEFPHAAKD
                     EFGRLLVAAAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPNR
                     TLIAGNIATAEGARALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIYQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAASDIVFQMLGGIRSGMGY
                     VGAGDIQELHENAQFVEMSGAGLIESHPHDVQITNEAPNYSVH"
     gene            9446..10309
                     /locus_tag="ACF4ZO_001543"
     CDS             9446..10309
                     /locus_tag="ACF4ZO_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RhaT/GlcU family sugar-proton symporter"
                     /protein_id="HFD5487063.1"
                     /translation="MEGIFYALIPMFTWGSIGFVSNKIGGKPSQQTLGMTFGALLFSL
                     AVWLIVRPEMTLQLWLFGILGGFIWSIGQTGQFHAMQYMGVSVANPLSSGSQLVLGSL
                     IGVLVFHEWTRPMQFVVGSLALLLLIIGFYFSSKQDDANAQVNHLHNFSKGFRALTYS
                     TIGYVMYAVLFNNIMKFEVLSVILPMAVGMVLGAITFMSFKISIDQYVIKNSVVGLLW
                     GIGNIFMLLAASKAGLAIAFSFSQLGAIISIVGGILFLGETKTKKEMRWVVTGIICFI
                     VGAILLGVVKS"
     gene            complement(10365..11471)
                     /gene="recF"
                     /locus_tag="ACF4ZO_001544"
     CDS             complement(10365..11471)
                     /gene="recF"
                     /locus_tag="ACF4ZO_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HFD5487064.1"
                     /translation="MWIKELELKHYRNYDHLLASFSSGLNVFIGNNAQGKTNFLEAIY
                     FLSLTRSHRTRADKELIHFDHSTVSLTGKIQRISGTVDLEINLSDKGRVTKINALKQA
                     KLSDYIGTMMVVLFAPEDLQLVKGAPSLRRKFIDIDLGQIKPVYLSELSHYNHVLKQR
                     NSYLKSAQQIDAAFLAVLDEQLAGYGARVMEHRIDFINALEKEANTHHQAISNGLESL
                     SLSYQSSVVFDKKTNIYQQFLHQLEKNHQKDFFRKNTSVGPHRDDLAFYINGMNANFA
                     SQGQHRSLILSLKMAEVSLMKALTGDNPILLLDDVMSELDNTRQTKLLETVIKENVQT
                     FITTTSLDHLSQLPEGIRIFHVTKGTVQIDSDIH"
     gene            complement(11473..11886)
                     /gene="yaaA"
                     /locus_tag="ACF4ZO_001545"
     CDS             complement(11473..11886)
                     /gene="yaaA"
                     /locus_tag="ACF4ZO_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HFD5487065.1"
                     /translation="MIYKLFTEFITLQALLKELGIIQSGGAIKGFLAETTVLFNGEDE
                     KRRGKKIRVGDKISLPDQDLIIIIVEPSQEEKEQFAEEMAEKTRVAALVKQMNQANKK
                     TSSKHNNRQSTTKKSLRATKKTKGKPTAPVRFPGI"
     gene            complement(12216..13130)
                     /gene="hasC"
                     /locus_tag="ACF4ZO_001546"
     CDS             complement(12216..13130)
                     /gene="hasC"
                     /locus_tag="ACF4ZO_001546"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     HasC"
                     /protein_id="HFD5487066.1"
                     /translation="MTKVRKAIIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVEE
                     ALKSGIEEILVVTGKAKRSIEDHFDSNFELEYNLQAKGKNELLKLVDETTAINLHFIR
                     QSHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITNASAKPLTKQLMEDYDKTHASTI
                     AVMKVPHEDVSSYGVIAPQGKAVKGLYSVDTFVEKPQPEDAPSDLAIIGRYLLTPEIF
                     DILERQVPGAGNEVQLTDAIDTLNKTQRVFAREFKGNRYDVGDKFGFMKTSIDYALEH
                     PQVKEDLKNYIIKLGKALEKSKVPTHSK"
     gene            complement(13312..14519)
                     /gene="hasB"
                     /locus_tag="ACF4ZO_001547"
                     /pseudo
     CDS             complement(13312..14519)
                     /gene="hasB"
                     /locus_tag="ACF4ZO_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992300.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase HasB"
     gene            complement(14555..15814)
                     /gene="hasA"
                     /locus_tag="ACF4ZO_001548"
     CDS             complement(14555..15814)
                     /gene="hasA"
                     /locus_tag="ACF4ZO_001548"
                     /EC_number="2.4.1.212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronan synthase HasA"
                     /protein_id="HFD5487067.1"
                     /translation="MPIFKKTLIVLSFIFLISILIYLNMYLFGTSTVGIYGVILITYL
                     VIKLGLSFLYEPFKGNPHDYKVAAVIPSYNEDAESLLETLKSVLAQTYPLSEIYIVDD
                     GSSNTDAIQLIEEYVNREVDICRNVIVHRSLVNKGKRHAQAWAFERSDADVFLTVDSD
                     TYIYPNALEELLKSFNDETVYAATGHLNARNRQTNLLTRLTDIRYDNAFGVERAAQSL
                     TGNILVCSGPLSIYRREVIIPNLERYKNQTFLGLPVSIGDDRCLTNYAIDLGRTVYQS
                     TARCDTDVPFQLKSYLKQQNRWNKSFFRESIISVKKILSNPIVALWTIFEVVMFMMLI
                     VAIGNLLFNQAIQLDLIKLFAFLSIIFIVALCRNVHYMVKHPASFLLSPLYGILHLFV
                     LQPLKLYSLCTIKNTEWGTRKKVTIFK"
BASE COUNT         5164 a         2623 c         2912 g         5234 t
ORIGIN      
        1 caacttgcgg tttaaaaaaa atcaaatttt ttttaaaaaa agtatagaca aaaaaaatca
       61 atctgctata atagtaagag tgttaaggag atatcctcca aaacttctgg tccgttggtc
      121 aaggggttaa gacaccgcct tttcacggcg gtaacacggg ttcgaatccc gtacggacta
      181 tcgcaattgt cattttggca atttttttct ttttccggca tagctcagtt ggtagtagcg
      241 catgactgtt aatcatgatg tcgtaggttc gagtcctact gccggagtga taagatattt
      301 cctaagataa tcttaggatt tttttattta gtaaaacaga tactcaggtc aaatactcaa
      361 tttactaatt attaaaccac taaatacagc attgtgaact aacaggattg tattttgcat
      421 taaaatagaa gttctgttct ttaattgtat agatgataac attaagttta attacaaaca
      481 ttaactgaag cttaattttt tacattttga aagcatgtct cccatttaat actgatgaat
      541 ataagattat tgtaaggagt caaaagattg aaatcgtatc agcgatgatt attgtcattt
      601 caatctttga aagagagtag tttaacatta accctcacga aaaatctgac ctttatatta
      661 tttgagttta ttagtaaaat cgataaaagc atctcaagta ttagaatatt tgtctagctc
      721 ttgagatgct tttagtatat tgactcattt gccaaattga taaaaaaatc tgattttttt
      781 ggactaaagt aatttagact ttatatctat gtacttatac aaaagcatat aagcgataat
      841 tcctacgcaa gatagagata accctaattt aaaaccatta ggaataaagg taaggataac
      901 acgtcccttt cctttaggaa tagtaactga tagaaatcct ccttgtgctt ttttgactgg
      961 aagatttttc ccatcttttt gtgctgacca acctttatcg taaggaagtg taaaaataag
     1021 agaacctttc gtttttgaat tataatcagt gattaccgta ttacttttag cgtaagtatg
     1081 aacatttttt tgcttaatac tattcattgc ttcaaggtaa gattcaatag acaaactata
     1141 aaaatgaggt tccttaaaac taatttgttt atcttttgga aaaacaaacg aaaatgtagc
     1201 aactttggca tcggcgaaat atcctaaatc aaaaaaagag taagcgttat ctgtagtata
     1261 tatgaaatta tgattatctg tctgaatacg cacctcttta gcatcaggat ttgaaaatat
     1321 aatattgggt atgctaacat agagttgact atgtttaggg atgttaattt gataattaag
     1381 ggtaacggag ttttgataat cagaagcttg tgcagatatt tgtccgttaa attgattagc
     1441 accagaaata agttgagctg gctgtaagtt aaaataggtt aaagatttcc cacttagttg
     1501 gttaagtaat ttggtttggt tatcaagggt attgacattt aggttgacat ctttgtaaac
     1561 attacgtgtt aatatagcta aagggctact atagtgattt tgataaagag tagtattccc
     1621 gctagttttt agttttgtaa atccaaattt atttagaggt ccttcgctaa gattatattt
     1681 tataccaagt agactgtcca taataatagt attgttttgg tatctaaggt ttaaatttgt
     1741 gcctttagac tgaaatccca atcgatccaa taaagaacta gatagtctat ttcttacaga
     1801 ggaaaattgt gaaatgccgt aataattaaa tttcatgcta tcgttccctg tttggggaag
     1861 tagcctttcc attctaaaaa aaggttgact attttttgac acagagttga caaggttgtt
     1921 aatatccttt aattgactat tatatatctg tcgtgatggg aatccccact ccttattaat
     1981 tccttgaagc tggtagtagg tgtttaaccc tgattcaaga aggctaaaga taagtatgaa
     2041 agcagaaata aaagtagatg ggatttgaga atttctaaac gaaaatagtg aaatagtata
     2101 acctaataat aaaaaaacac taagtaaaaa aagagttaaa ggtagaaaat tatattgttg
     2161 agaaaagcta taaggaagag atgtcagtat aatgaggaaa ataaaagcaa aacctgcttt
     2221 tatttgagtc acttctttta gtcgagagag agtctcacat gcgagtaata ggataactat
     2281 ggaaaaagac caagcgtagc ggtgcaaaaa catatttggt gagtgcatcc cctgccaaaa
     2341 aagatcaagt ggctgtaggt aaaaacttat tataataaaa gttaacaagc aggcattggc
     2401 taattttatt tttaaaggga tactttctaa agtaaaataa ataacactaa gcattagggg
     2461 aaataatcct acgtaaatca taggcagagc attaaacttg gtagtatcgt acactcctat
     2521 tgagagctta gcaggtatat ccaaaaacca agcattgttc gtaactaact gttttaccgg
     2581 ggatagattc tctccataag ttgacaaatc tagataggta ggaagtatta ctagagcact
     2641 tgttaaagca gcacatattg acacagctgt aaacctaaca aaagcgataa acattttgtt
     2701 aaaatcattg agacgtaaaa gacaaactaa ggtgtaaaga atacaaaaaa gagcaatcat
     2761 gtagccaaag tagtaatttt gaatgaataa taatgatatc gaaagataat aagttctggt
     2821 tttattttct gtgataagtt tatttaatcc aagtacaaca agtggaagaa gaatgaaaac
     2881 atctaaccaa gaatttagtt ccatttgact tgtcaagaag ctcattaagc tataaaaaac
     2941 tgagatggaa atcatcaaga aagcactgat ttttggatat aatctatgaa aagaatagca
     3001 tgcagctaat cctattaacc caaattttat caaggtaaac aaatagatag catctggcat
     3061 agaggctaaa ttaaaaaaga aaagtaatgg agaaaagaaa ctgccaagat aataacacat
     3121 taaagcataa aaatttatcc ctagtccgct tgtaaaggta taaaaaaaac tatcagaacc
     3181 gtgcatgatg ttacgaaagt tctgcgcaaa aataacatac tgatgaaaag catcactagc
     3241 tagaattgtt ttatcactat tataataaat gcccatcgat agaaggatga taaatataat
     3301 actaagaggg aacaaaaaac tagcaagtcc agcaattatc catttattat tatttttcat
     3361 aaattatatg gtctttcgtt tacaaatttt aaaaaagagg ctaggaagag atcttcttag
     3421 ccatctcatt tatcataagg ttttatttcc aaagttcagc aactcgggct tggacttctg
     3481 gattgtcaag gaattcgtca taagtttcat ctatacggtc gataacacca ttttttgaaa
     3541 taacaacgat gtggttagca atcgtttgaa taaattcatg gtcatgactg gcaaagataa
     3601 cagattcttt gaagtctttg ataccatcat taagacttga aatagattcc aaatccaagt
     3661 gatttgttgg atcatcaaga ataagaacgt ttgatttcaa tagcatcaac ttagaaagca
     3721 tgacacgcac tttttcgcca ccggaaagaa cgttaacaga ttttttaact tcgtctccag
     3781 agaaaagcat ccgtcctagg aaaccacgta aaaaagtatc atcatcttca ccttttgagg
     3841 caaattgacg taaccattca agaatagatt cttccgtggc aaaatctttt gaattgtctt
     3901 taggcaagta agaacgactt gttgttactc cccatttaat ggttccttcg tagtcaatat
     3961 catctgctaa agcacgcata agagcggttg tttgaatatc attttgacca ataatagcag
     4021 ctttgtcacc tggacgtaaa atgaaactga tattatcaat gattttctct ccatcgatcg
     4081 ttacagaaag attttcaaca gtgaggaagt cattccccat ttcacgctct gctttaaaat
     4141 taataaatgg gtatttacgg cttgagggaa caatttcttc taattcaatc ttatcaagca
     4201 tttttttacg agaggttgct tgttttgatt tagatgcgtt tgctgagaaa cgggcaacga
     4261 attcttgtaa ttctttgatt ttttcttcgg ctttagcatt gcggtcagct tgtaaacgag
     4321 cggccagctc agaagattgt ttccagaaat cgtagttacc cacaaagagt ttgattttac
     4381 caaagtcaag gtcggccatg tgagtacata ctttattcaa gaagtgacgg tcatgggaaa
     4441 caacgatgac tgtattttca aaatcaatca agaaatcttc caaccatgaa atagattgaa
     4501 tatcaagacc attggttggc tcgtcaagta ataaaacgtc aggcttacca aagagcgctt
     4561 tagcaagaag gactttcact ttatctccat tagccagttc actcatattt tggtagtgaa
     4621 ggtcttctgg aatatttaga ttttggagaa gttgagaagc ttcactttct gcctcccagc
     4681 cacctaattc agcaaagata ccttctagct cagcggcacg aaccccatct tcttctgaaa
     4741 aatctgcttt catatagata gcgtcttttt ctttcatgat attgtaaagt tgctcattac
     4801 ccatgattac aacatcaatc gcacgttctt cttcataatc aaaatgattt tggcgaagaa
     4861 cagataagcg ttcgtcaggt cctaaagaga tatgaccagt acttggttca atatctcctg
     4921 caaggatttt aagaaaagtt gattttccgg caccattcgc accgattaag ccgtaagtat
     4981 tgccggctgt gaatttgata ttaacatcat caaatagttt tcgatcacta aagcgtagtg
     5041 atacatcaga aactgtaagc aatttgtcac ctcattttat ttatctaagc ttcattgtac
     5101 ctaaaatagt cccctttttc aatcagaaaa gggctaatca ctacataggc aataaaacgt
     5161 ctttgtcttc acgtttgtat tgtttagtca aactaaatcc tcttcccata acttgagctg
     5221 ctggcatgac aacaataaag gctgtatcgt caatttcgag gattttttct tggagagtag
     5281 gtaattcgtg acttgataca atagccatta acataatttt atcagaagta gtataaccac
     5341 cgcgaatagg aagtttagtc actccacgat ccataacagt tgtgatatat tctcgaatag
     5401 cttgataatc tttggaaata atcataacat ttttggatga gtcaaagcca ttttccataa
     5461 cactaatcac ataaccaatt acgaaaagtc caatcgtaga atacatcacg tcatctgcag
     5521 aaagtgcaat aaatcccata aggacactaa taccatctac aattgtcatt gcaactccaa
     5581 gagataaagg agagtattta tgaagtattt gtgttagaat tccagttcct cctgtcgaag
     5641 agtttcccca aaaaaccatt cctaaaccaa tgccacagat aataccacca aaaatagctg
     5701 ctaacaactg attgtgtgtc agagtaggta atgaattggt tgaacggatg gcaataggat
     5761 atatccaaga accataaagt gttttaataa aattttgttt tccaagaaag aagtaacaca
     5821 ttaataataa gggaatatta ctagccatta aaaaaagcga cggactaatg ccaaatagag
     5881 cttttataac aactgcaata ccaaccatac cccctgatgc aatatgattg tcgacaaaca
     5941 ttgtattgaa accaatagct gttatgaatg agccaattgt gacaagtagt aaatcaatcc
     6001 ctcgtttttt catgctttta atctccttta taactggtta aaaatagtag actcattatc
     6061 tcttaaatgt actgagaccg tcaagtcata ttttcaaaaa atctggtgaa cttgacaaga
     6121 agtttaaaat ttcatagaat aaatctaaat tagaagagta ttcttttcat gtttttagag
     6181 agttagtggt cggtgcaagc taacaacaga aaaggtgaaa tggactaatg attatttgaa
     6241 aggaaaccat aactttcagg ttggcacccc ttaccgtgca gcttctttca ttgagaagat
     6301 tgagatagta tctcgttttg ataaagcaga tgctaattga ggtggtaccg cgtattactt
     6361 gtaataacgc cctcacgttt taatagcgtg gggacttttt gctatatcaa gagatagtta
     6421 gggagaaaat gatgacaaaa cctattattt taactggaga tagaccaact ggaaaattac
     6481 atttaggtca ttatgtcgga agtcttaaaa atcgtgtctt tttacaaaat gaaaacaagt
     6541 ataagatgtt tgttttcttg gccgatcaac aggcactgac ggatcatgct aaagaatccg
     6601 aattaattca agaatctatt ggaaatgttg ccttggatta cctctctgtc ggtttggatc
     6661 cgaagcaatc aacgattttt attcaaagtc agattccaga gctagctgaa ttgagcatgt
     6721 attatatgaa tctggtatca ttagcacgtt tggaaagaaa tcccactgtt aaaaccgaaa
     6781 ttgctcagaa aggttttggc gaaagtattc catctggttt tttggtttat ccagtatcac
     6841 aggccgctga tattacagca tttaaagcga atttagtacc tgtaggtaac gaccagaaac
     6901 cgatgattga acaaacacgt gaaattgtga gaagtttcaa tcatacttac catacagact
     6961 gtttagtaga acctgaaggt atttatccag aaaatgaaaa agctggacgc ttacctggtc
     7021 ttgatggcaa tgccaaaatg tctaaatcat tgggaaatgg aatctatctt tcagatgatg
     7081 cagataccgt tcgcaaaaaa gtgatgagca tgtatactga tccaaatcat attaaaatag
     7141 aagatcctgg tcaaattgaa gggaatatgg tctttcatta tttggatatt tttgctagaa
     7201 aagaagatca agctgatatc gaagcaatga aagagcatta tcaaagaggt ggtttaggag
     7261 atgtgaaaac gaaacgctac cttctagata ttttagaacg tgaattagca cctattcgtg
     7321 aaagacgttt ggagtacgct aaagatatgg gagaggtgtt ccgtatgtta caagaaggta
     7381 gtcaaaaagc aagaactgtg gcagccaaga ctttatcaga agtgaagtca gcaatgggta
     7441 ttaattattt ttaatgtttt agagaaaaag ctaagttagt aatgataaga taattactat
     7501 tatcaaagca ggacctaatt tgtcatttct ttacaggata gtagagatta tgttttatat
     7561 agtcttattt ttgattaaaa ataagaccca aatgaatttt ttgattaata aaaaacggat
     7621 aatactgata tattatgctg atagtgactt cagctgtagg aatattttat tgacaaatga
     7681 ttttagcgtg atatgatagt aacaataaaa aatagaccag ggtaatattc cctaaaaata
     7741 aaagaaaaga ggattatctg gatgtcaaat tgggacacta aatttttaaa aaaaggctac
     7801 acttttgacg atgtcttgct tattccggca gagagtcatg ttcttccaaa tgaagttgat
     7861 ttaaagacaa aactcgcaga caatttgaca ttaaatattc ctattattac agcagctatg
     7921 gatacggtta ctggtagtaa aatggctatt gcaattgcgc gtgcgggtgg tttaggtgtt
     7981 attcataaaa acatgtctat tactgagcaa gcagaagaag ttcgcaaggt aaaacgttct
     8041 gaaaatggtg tcatcattga tccattcttc ttaacacctg aacacaaggt ttcagaagct
     8101 gaagaattaa tgcagcgcta ccgtatcagt ggtgtgccaa ttgttgaaac tttagcaaac
     8161 cgtaagttgg tcggtatcat tactaatcgt gatatgcgtt ttatttctga ttacaatgca
     8221 ccaatctctg aacatatgac tagtgagcac ctcgttacgg ctgctgttgg tacagatctt
     8281 gaaactgcag aacgtattct tcatgaacac cgtattgaaa aacttccttt ggttgataat
     8341 agcggtcgtc tgtctggttt aatcactatc aaagatattg aaaaagtaat cgaattccca
     8401 catgctgcta aagatgaatt tggtcgtctt ctggtcgctg ctgcggtagg tgttacctca
     8461 gatacttttg agcgtgccga ggccttgttt gaagctggtg cagatgcgat tgttattgac
     8521 acagctcatg gtcattcggc tggtgttctt cgtaaaattg ctgagattcg tgctcatttc
     8581 ccaaatcgta ctttgattgc tggaaatatt gccactgctg aaggtgcgcg tgctctttat
     8641 gatgcaggtg ttgatgttgt taaagtgggt attggtcccg gatctatctg taccactcgt
     8701 gtggttgcag gtgtcggtgt tcctcaagtg actgctattt acgatgctgc tgctgttgct
     8761 cgtgaatatg gcaaaacgat tattgctgat ggtggtatca agtattctgg cgatattgtt
     8821 aaggctcttg cagccggtgg taatgctgtt atgcttggat caatgtttgc aggtactgat
     8881 gaagctccag gtgaaactga aatctaccaa ggccgtaagt tcaaaactta tcgtggaatg
     8941 ggttccattg cagctatgaa gaaaggatca agcgatcgtt acttccaagg ttccgtaaat
     9001 gaagctaata aactagttcc agaaggtatt gaaggccgtg ttgcttataa aggagctgct
     9061 tcagatattg tcttccaaat gttaggtggt atccgctcag gtatgggcta tgttggcgca
     9121 ggtgacattc aagaattaca tgaaaatgct caatttgttg aaatgtcagg tgcaggcttg
     9181 attgaaagtc atccacatga tgtccaaatc acaaacgaag caccaaacta ttctgtgcac
     9241 tgataattta atttagtaac tttaagggct gacatattgt gccagctctt tttttatatt
     9301 aaaaaatgat aaaatataat aacaattttc ggataacttt tattgttttt tcttagtaaa
     9361 taagctataa ttagtcttta catgaaacca ttttatgata gaattattat aatctttaaa
     9421 gatttactat aaaggagata acattttgga aggtattttt tatgcactta ttcccatgtt
     9481 tacatgggga agcattggat ttgttagtaa caaaattgga ggaaaacctt cgcaacaaac
     9541 tctaggaatg acttttgggg ctttattatt ttcattagct gtttggttaa ttgttagacc
     9601 tgagatgaca ctgcaacttt ggctttttgg aatattgggt ggttttatct ggtcaattgg
     9661 tcaaactggt caatttcatg ccatgcaata tatgggagtc tccgttgcca atcctttgtc
     9721 aagtggctct caacttgttc tgggaagttt gattggtgtg ctcgtttttc atgaatggac
     9781 aagacctatg caatttgtag taggaagtct agcactatta cttctgatta ttggttttta
     9841 cttttctagt aaacaagatg atgctaatgc acaagtcaat caccttcata atttttcaaa
     9901 aggatttagg gcgctcactt attcaacaat tggttacgtg atgtatgctg tattatttaa
     9961 taacatcatg aaatttgaag ttttgtcagt cattttaccc atggcagtag gtatggtttt
    10021 aggagctata actttcatgt catttaaaat ttccattgac cagtatgtga ttaaaaatag
    10081 cgttgttgga ttactttggg gcattgggaa tatttttatg cttttagctg catcaaaagc
    10141 aggacttgct attgccttta gtttctcaca attaggtgcc atcatttcga ttgtcggagg
    10201 cattttattc ctaggcgaaa ccaaaaccaa aaaagaaatg cgttgggttg tcacaggaat
    10261 tatttgtttt atcgtaggtg ctattttatt aggtgtggtc aaatcttaat cgccacataa
    10321 catcaaaaaa aggctcagtt taactgaacc cttttttgat gttattagtg aatatcagaa
    10381 tcaatttgaa cggttccttt tgtcacgtgg aaaatacgga taccttctgg caactgtgac
    10441 aggtgatcca aacttgttgt tgtgataaag gtttggacat tttctttaat tactgtttca
    10501 agtaactttg tttgtcgtgt attgtctagc tcgctcatga catcgtctag taaaagaatg
    10561 ggattatctc cagtcaaggc cttcattaaa ctaacttcag ccatttttaa ggaaagaata
    10621 aggctgcggt gctgaccttg actagcaaag ttagcattca tcccgttaat gtaaaaggct
    10681 aagtcatcgc gatgtggacc aacgctagtg tttttacgga agaaatcttt ctgatgattt
    10741 ttttcaagtt ggtgtaaaaa ttgttggtaa atattagttt ttttgtcaaa gacaactgac
    10801 gactgatagg agagagagag actttctaaa ccatttgaga tggcttggtg atgagtattt
    10861 gcttctttct ctaacgcatt gataaaatca atacgatgtt ccatgacacg ggctccatag
    10921 ccagctaatt gctcatctag aacagctaga aaagcggcat caatttgttg ggcacttttt
    10981 aaatagctat tacgctgttt aagcacgtgg ttataatggg ataactcaga taagtaaaca
    11041 ggcttaattt gaccaaggtc aatgtcgata aatttgcgac gaaggctagg tgctccctta
    11101 actagttgca aatcttctgg tgcaaaaagc acaaccatca tcgttccaat ataatcagat
    11161 aattttgctt gcttcagcgc attaatcttt gtcacacgtc ctttatctga tagattgatt
    11221 tctaaatcaa cagtaccact aatacgctga atcttaccag taagagaaac agttgagtga
    11281 tcaaaatgaa tcaattcttt atcagccctc gtgcgatgac ttctagtaag tgatagaaaa
    11341 tagattgcct cgagaaaatt ggtttttcct tgagcattat taccgataaa gacatttaaa
    11401 cccgacgaaa atgaggcaag caggtggtca taattgcgat aatgttttaa ctctaactct
    11461 ttaatccaca tactagatac ctgggaagcg gacaggtgca gttggtttac ctttagtttt
    11521 cttagttgct cttagtgatt ttttggtagt agattgacga ttgttatgtt tagaagaagt
    11581 ctttttgtta gcttggttca tttgtttcac tagagccgct acacgtgtct tttcagccat
    11641 ttcttcggca aattgttctt tttcttcttg actaggctca acaataatga taattaagtc
    11701 ttggtcaggt agagaaatct tatcccctac tctgattttt ttgcctcgac gtttctcatc
    11761 ttcaccatta aatagaacgg ttgtttcagc gagaaatccc ttgatagcgc caccactttg
    11821 gataattcct aattctttaa gaagggcttg tagggtgata aattctgtaa ataatttgta
    11881 tatcattgtc atctccattt tgtcattcaa gtcattatag cataaaacag aaataaataa
    11941 taatagctga ataagagcta tttataaagt atcatactcg tccaaataac tatttagttt
    12001 tgaagttctt gttaattagt tttaacaaaa gctgtactta tgtctatcat ttttctacgt
    12061 ataaatccta ttattaatat gtccctctag taaagttgta taacacaaaa cttttatatt
    12121 ttggaacgtt gacaattttc aagatataaa cttaagttgc tataaacaag gaaaaaagta
    12181 aagtaccaac acattacttt gaatgtgttg gtactttact ttgaatgtgt tggtacttta
    12241 cttttttcca aagcttttcc tagtttgata atgtaatttt tcaagtcctc tttgacctgt
    12301 gggtgttcta aggcatagtc gatagatgtt ttcatgaatc caaatttatc cccaacatcg
    12361 taacgattgc ctttaaattc tcgtgcaaag acacgctgag ttttattgag ggtatcgata
    12421 gcatctgtga gttgcacttc gttacctgct ccagggacct gtctttccaa aatatcaaaa
    12481 atttcagggg ttaggaggta acgaccaata atagccaaat cactaggcgc atcttctggt
    12541 tgtggttttt caacaaaggt gtctacactg taaaggccct tgacagcctt gccttgaggg
    12601 gcgataaccc catagctaga cacatcttca tgaggaactt tcatcacagc gatagtggat
    12661 gcatgcgtct tgtcatagtc ctccatgagt tgtttggtga gaggtttagc ggatgcattt
    12721 gtaatgtcca ttaagtcatc tccaagcatg accacaaagg gttcattgcc cacaaaggct
    12781 ttggcttgta agacagcatc tcccagtcct cttgggtggc tttgacggat aaaatgaagg
    12841 ttaatggcag tggtttcatc cactaatttc aacagttcat ttttcccctt agcttggagg
    12901 ttgtactcta attcaaagtt tgaatcaaaa tggtcctcga tagagcgttt agcttttccg
    12961 gtcaccacaa ggatttcctc gatgccagat tttagcgctt cttcgacgat aaactggatg
    13021 gttggtttat caacgatggg caacatctct ttggcaagag ctttggtagc aggtaaaaaa
    13081 cgtgttccta gacctgcagc aggaataatg gcttttctga ctttggtcat cagtaactcc
    13141 tcacttttta taatctatgg cttagtgcca ttcgttttca gaacggaatt catttgacat
    13201 catgttacgt tttcatatga tttttcgact atttcatagt gctcaatcat accaccaact
    13261 gcagttcttt taaagtaaaa atgaatatta ttgttataga tgaagacatg gctagtctct
    13321 accaaaaata tctctactgt aaactttatt tttaacatct tgtaattcat tatcatagcg
    13381 attagttacg ataatatttg cttgtttctt gaaattctct aaatcattta caagtacaga
    13441 ttgatcttca gattcaagtt tgtttaacat tggctcataa ataattatct taatgtcttt
    13501 acttttaaga atgtcaataa catctttgat agcactttct ctaaagttat ctgagttact
    13561 tttcataatt aaacggtaaa ccccgactac ttttactggg gactcctgct cttttaagac
    13621 gttgataatt tgcttagcaa tataggactt gcgcacatta tttgatgaaa cgatagcttc
    13681 aattagcgtt tggggaatat tattgtaatt tgccaataat tgcttcgtat ctttaggtag
    13741 acaataacct ccataaccaa atgatgggtt attataatgc attcctattc gatcatcata
    13801 agaaattcct tgaataatca tgtgactatt taattttctt gattctgcgt aagtgtctaa
    13861 ctcattaaaa taagctaccc ttaacgctaa ataagtattg gcaaatagtt ttactgcttc
    13921 agcttctgaa gctcccataa taagtactgg tacattattt ttttagctgc agactttaat
    13981 aaaagtgcaa atttttctgc gtctgccttt acttttggag aatcgttttc ttcacaagaa
    14041 acaataattc ggcttggata taagttgtca tataaagctt tagattctct taaaaattca
    14101 gggctgaaga taatacgatc agtttggaat ttctgtctca tttcagtaat gaaacctatt
    14161 ggaattgttg atttgatgat aagagttgca tggctattaa cgcttagtac ctctttgata
    14221 actgtttcaa catgctgtgt atcaaaataa ttaattctac tgttgtaatt tgtaggtgtg
    14281 gcaataatga ccagttccgc ttctttataa gctgctttgc tatctaaagt tgctttaata
    14341 gataattgct tactttttaa gtaatattca atatattcat cttgaattgg tgataagcca
    14401 ttattaatct tatcaacttt agagggaaga atatcaacaa tagtgacttc gttttgaagt
    14461 gataaaagaa ctcctagtga taatccaaca tatcctgatc cagcaactgc tattttcata
    14521 aaattactcc ttctctaact actcgatgca tatattattt aaaaatagtg acctttttac
    14581 gtgttcccca ttccgtattt ttaatggtgc ataaagaata aagttttagg ggctgtaaga
    14641 caaacaagtg taatattcca tacagaggag ataacaaaaa actagcagga tgtttgacca
    14701 tataatgaac attacgacat aaagcaacga taaagatgat ggataaaaag gcaaaaagtt
    14761 taataaggtc taattgaata gcttgattaa acaaaagatt cccaattgcg acaatcaaca
    14821 tcataaacat aacgacttcg aaaatagtcc ataaggcaac gatgggatta gaaagaattt
    14881 ttttaacaga aataatagat tctctaaaaa aagatttatt ccatcgattt tgttgcttta
    14941 aataactttt taattggaaa ggtacatcag tatcacatct agctgttgat tggtagacag
    15001 tgcgtcctaa atcaatagca taatttgtta aacatcgatc atccccaatg ctaacaggta
    15061 aacctaggaa tgtttgattt ttatagcgct ctaagttagg aataatcact tcacgtcgat
    15121 aaatactcaa tggtcctgag caaactaaaa tattacctgt taatgattga gcagcacgct
    15181 ccaccccaaa ggcattatcg taacggatat ctgtaagtcg cgttaataga ttagtttgtc
    15241 tgtttctagc attcaaatgt cctgttgcag cataaactgt ctcatcattg aagcttttta
    15301 ggagttcttc taaggcattt ggatagatat aagtatctga gtctacggtt aaaaaaacgt
    15361 cagcgtcaga tctttcaaat gcccacgctt gagcatggcg ttttccttta ttgacaaggg
    15421 aacggtgaac gataacgttt cgacaaatat ccacttctct atttacatac tcttcaatta
    15481 attgtattgc atctgtgttt gaactcccat catcaacaat ataaatttct gataacggat
    15541 aggtctgtgc taacacactt ttaagtgttt ctaataatga ctcggcatct tcattataag
    15601 aaggaattac agcagcaact ttatagtcat gtggatttcc tttaaatggc tcataaagga
    15661 aagataatcc aagtttgata actagatagg ttattaatat tactccataa attcctacag
    15721 ttgatgttcc aaatagatac atatttagat aaatcaagat agatatcaaa aaaataaagg
    15781 ataaaacaat taaagttttt ttaaaaatag gcacaattac acctctttct tttttaattt
    15841 ccttgaaaga aaggacctca atattctaac ataaataaga aataatgtcg actagatata
    15901 gagatatttt taataaaatt gtgtttccat taa
//
LOCUS       DAXMQE010000039        15753 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.039, whole genome shotgun sequence.
ACCESSION   DAXMQE010000039 DAXMQE010000000
VERSION     DAXMQE010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15753)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15753)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15753
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.039"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            <1..1451
                     /gene="lepA"
                     /locus_tag="ACF4ZO_001549"
     CDS             <1..1451
                     /gene="lepA"
                     /locus_tag="ACF4ZO_001549"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="translation elongation factor 4"
                     /protein_id="HFD5487068.1"
                     /translation="LDNDLEILPVINKIDLPAADPERVRHEVEDVIGLDASEAVLASA
                     KAGIGIEEILEQIVEKVPAPTGDVDAPLQALIFDSVYDAYRGVILQVRIVNGIVKPGD
                     KIQMMSNGKTFDVTEVGIFTPKAVGRDFLATGDVGYVAASIKTVADTRVGDTVTLANN
                     PAKEALHGYKQMNPMVFAGIYPIESNKYNDLREALEKLQLNDASLQFEPETSQALGFG
                     FRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVVYHVHTTDEDMIEVSNPSEFPAPTR
                     VAFIEEPYVKAQIMVPQEFVGAVMELSQRKRGDFVTMDYIDDNRVNVIYQIPLAEIVF
                     DFFDKLKSSTRGYASFDYDMSEYRRSQLVKMDILLNGDKVDALSFIVHKEFAYERGKI
                     IVEKLKKIIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGGDVSRKRKLLEKQ
                     KAGKKRMKAIGSVEVPQEAFLSVLSMDEDAKK"
     gene            1718..2806
                     /gene="slc2"
                     /locus_tag="ACF4ZO_001550"
     CDS             1718..2806
                     /gene="slc2"
                     /locus_tag="ACF4ZO_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored collagen-like adhesin Scl2/SclB"
                     /protein_id="HFD5487069.1"
                     /translation="MLTFGGASAVKADDNKSDEEKIEARSSLIKRLHDEISGQSNNQI
                     PKVPDSTYVGPPNISDIENDVTAIREYLDSINSFLVGQKNSDKKWKLELTQGIQDRLL
                     DGKDGRDGDKGDPGPRGATGPAGPAGPQGPRGDKGETGDKGDQGPVGPVGPQGMPGAK
                     GDRCETGPAGQNGKDGLPGKDGKDGQDGKDGLPGKDGKDGQNGKDGLPGKDGKDGQDG
                     KDGLPGKDGKDGQDGKDGLPGKDGQDGKDGLPGKDGKDGQPGKPAPKTPEVPQKPDTA
                     PDTPKPPQIPGQSKDVTPAPQNPSNRGLNKPQTQGGNQLAKTPAAHDTHRQLPATGET
                     TNPFFTAAAVAIMTTAGVVAVAKRQENN"
     gene            2992..3429
                     /gene="msrB"
                     /locus_tag="ACF4ZO_001551"
     CDS             2992..3429
                     /gene="msrB"
                     /locus_tag="ACF4ZO_001551"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033743 - peptide-methionine (R)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HFD5487070.1"
                     /translation="METSEELKQRIGDLSYEVTQHAATESPFTGEYDDFFEKGIYVDI
                     VSGEVLFSSLDKFNSGCGWPAFSKPIENRMVINHDDSSYGMRRVEVKSREAGSHLGHV
                     FSDGPKEAGGLRYCINSAALKFIPYEQMEKEGYAQWLTLFDET"
     gene            3559..4578
                     /locus_tag="ACF4ZO_001552"
     CDS             3559..4578
                     /locus_tag="ACF4ZO_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family protein"
                     /protein_id="HFD5487071.1"
                     /translation="MSTHLRKLPGLLLCLLLALPAWYLGRLFPIIGAPVFAILLGMLL
                     ALFYEHRDKTKEGISFTSKYILQTAVVLLGFGLNLTQVMAVGMQSLPIIISTIATALL
                     VAYGSQKWLRIDVNTATLVGVGSSICGGSAIAATAPVIKAKDDEVAKAISVIFLFNML
                     AALLFPSLGQLLGLSNEGFAIFAGTAVNDTSSVTATATAWDALHHSNTLDGATIVKLT
                     RTLAILPITLGLSLYRAKKEHDIVTEEGFSLRKSFPRFILFFLLASLITTLMISLGVS
                     ADVFHSLKTLSKFFIVMAMAAIGLNTNLVKLIKTGGQAILLGAICWVAITLVSLAMQL
                     SLGIW"
     gene            4785..5210
                     /locus_tag="ACF4ZO_001553"
     CDS             4785..5210
                     /locus_tag="ACF4ZO_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000823118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFD5487072.1"
                     /translation="MKRKFLIGSHGRLASGLQSSIDILAGMGQALETIDAYVDDSDYT
                     SQIDDFIAGVAADEQGLIFTDLLGGSVNQKMVTAVMNSGKDNIFLITNSNLATLLSLV
                     FLKPGEALTKDEIVTVINESQVQLVDLVPETNSEDDFFD"
     gene            5229..5720
                     /locus_tag="ACF4ZO_001554"
     CDS             5229..5720
                     /locus_tag="ACF4ZO_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFD5487073.1"
                     /translation="MITQIRVDDRLVHGQVAVVWTKELNAPLLVVANDEAAKNEITQM
                     TLKMAVPNGMKLLIRSVEDSIKLFNDPRATDKRIFVIVNSVKDACAIAKEVPDLEAVN
                     VANVGRFDKSDPASKVKVTPSLLLNPEEMAAAKELVSLPELDVFNQVLPSNTKVHLSQ
                     LVN"
     gene            5737..6546
                     /locus_tag="ACF4ZO_001555"
     CDS             5737..6546
                     /locus_tag="ACF4ZO_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017644846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HFD5487074.1"
                     /translation="MLVPATMAALAVLICFGGNYLTGQSMMERPLVVGLVTGLLLGDM
                     KVGILMGASLEALFLGNVNIGGVIAAEPVTATAMATTFTIISHIDQKAAMTLAVPIGM
                     LAAFVVMFLKNVFMNIFAPMVDKAAAANHQGKLVMLHYGTWIIYYLIIASISFIGILV
                     GSGPVNAFVEHIPQNLMNGLSAAGGLLPAVGFAMLMKLLWTNKLAVFYLLGFVLTAYL
                     KLPAVAVAALGAVICVISSQRDLELDAITRGAISKQTTFDSKESEEEDFFA"
     gene            6543..7370
                     /locus_tag="ACF4ZO_001556"
     CDS             6543..7370
                     /locus_tag="ACF4ZO_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFD5487075.1"
                     /translation="MTSQDNLTKEDRKMLRSVFWRSWTMNASRTGATQYHAVGVIYTL
                     LPVINRFYKTDKDKAEALVRHTTWFNATMHINNFIMGLVASMEKKNSEDPDFDASAIT
                     AVKASLMGPISGVGDSFFWGILRVIAAGIGISLASAGSAMGAVVFLLLYNIPAFIIHY
                     YSLYGGYSVGAGFIKKLYESGGIKIVTKTSSMLGLMMVGSMTASNVKFKTILTVAAKG
                     AKEAASIQDYLDQLFIGIVPLMVTLAAFWLLRKKVNINWIMFGIMFLGIILGLLGIC"
     gene            7506..9155
                     /locus_tag="ACF4ZO_001557"
     CDS             7506..9155
                     /locus_tag="ACF4ZO_001557"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFD5487076.1"
                     /translation="MRGEQVEEHFKKQLQDDISRHFSYQSLMLSLLLIGLFIIFSLAP
                     QQLGLYRDINATATRYHRLISKQEALLDELGKNSLLPFLNKKLNTADLSKHYFHLRHS
                     SQTSPELLLFSPNQGLLFASNPHLGNVFSKSVYIQEVLRAAHPPKTLFKVAMDSEDGH
                     YLMIIKPMIDQNQLKGYAFLVMSGKDVLHPTKTLTSELVIADKLDNTFTFSNREFIAS
                     SLDKINSQYLHHYFVFQDNRAFITRKVALQGGLWLYMYRPLIPMVSVMLFSLISSAVI
                     FVILQRKSSGLANRIAAKNSRAINQMVRDMSAISRQEKRRIDLESQDEFQYLSDQINQ
                     MVERLQQLHDKTLDLETQKLLFEKRMLEAQFNPHFLYNTLETILITSHYDSALTEKIV
                     IQLTKLLRYSLTDSSKPVLLKDDLSVIESYLVINQVRFEELQYSINLSPDLDSLAVPK
                     LFLLPLIENAIKYGLKERHDVKINIACYYQDDHIIFSVRDNGSGIDAHHQKVIREQLE
                     AGESHHGLINSYRRLKYHFSEVSLVFDQGDKQFNVSYHVKE"
     gene            9159..9947
                     /locus_tag="ACF4ZO_001558"
     CDS             9159..9947
                     /locus_tag="ACF4ZO_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFD5487077.1"
                     /translation="MYKLVIIEDEHIIRKWLRYAIDYKALDILVIGEAKDGKEGAVLI
                     KESQPDIVLTDINMPIMTAFDMFEATKDQTYAKIILSGYADFPNARSAIHYGVLEFLT
                     KPIEKAALWECLQTIIAKIEKQKGSNQKTDACVYIPLPQMTDQIPEVVKDILEWVHAH
                     FQDKISTSRLAHDLGYSESYIYQNIKKHLQMPLSDYINQYRINQAIQLMQQEPDLMVY
                     EIAQAVGIYDYRYFDRVFKKYLGQTVKAFKEEHFMKDTDRSKPC"
     gene            9941..10987
                     /locus_tag="ACF4ZO_001559"
     CDS             9941..10987
                     /locus_tag="ACF4ZO_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HFD5487078.1"
                     /translation="MLKLKRKWLLSFLLVIIILAIVNIAMYIFSSSKKDSAKELVILT
                     PNSQTILTGTIPAFEEKYGVKVRLIQGGTGQLIDQLGRKDKPLNADIFFGGNYTQFES
                     HKDLFESYVSPQVSTVISDYQLPSHRATPYTINGSVLIVNNELARGLHITSYEDLLQP
                     ALKGKIAFADPNSSSSAFSQLTNILLAKGGYTSSEAWEYVKRLLLSMNSIRATSSSDV
                     YESVAEGKMIVGLTYEDPCINLQKSGANVSIVYPDEGTVFVPSSVAIIKKAKAMKEAK
                     QFINFILSSDVQNAFGQSTSNRPIRRDAQTSHEMKPLDEIITLKEDYGYVTRHKKKIL
                     NTYNRLHEALERGK"
     gene            11100..12497
                     /locus_tag="ACF4ZO_001560"
     CDS             11100..12497
                     /locus_tag="ACF4ZO_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent succinate-semialdehyde
                     dehydrogenase"
                     /protein_id="HFD5487079.1"
                     /translation="MAYQTIYPYTNEVLHTFDNMTDQDLADVLERAHLLYKKWRKEDH
                     LEERKAQLHQVANILRRDRDKYAEIMTKDMGKLFTEAQGEVDLCADIADYYADKADEF
                     LMSTPLETDSGQAYYLKQSTGVILAVEPWNFPYYQIMRVFAPNFIVGNPMVLKHASIC
                     PRSAQSFEELVLEAGAEAGSITNLFISYDQVSQVIADKRVVGVCLTGSERGGASIAEE
                     AGKNLKKTTLELGGDDAFIILDDADWDQLEKVLYFSRLYNAGQVCTSSKRFIVLDKDY
                     DRFKELLTKVFKTAKWGDPMDPETTLAPLSSAQAKADVLDQIKLALDHGAELVYGGEA
                     IDHPGHFVMPTIIAGLTKDNPIYYQEIFGPVGEIYKVSSEEEAIEVANDSNYGLGGTI
                     FSSNQEHAKAVAAKIETGMSFINSGWTSLPELPFGGIKHSGYGRELSELGFTSFVNEH
                     LIYIPNKTNNSNTKV"
     gene            12599..14395
                     /gene="uvrC"
                     /locus_tag="ACF4ZO_001561"
     CDS             12599..14395
                     /gene="uvrC"
                     /locus_tag="ACF4ZO_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0009381 - excinuclease ABC activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HFD5487080.1"
                     /translation="MNELIKHKLELLPDSPGCYLHKDKEGTIIYVGKAKNLKKRVRSY
                     FRGSHDTKTELLVSEIVDFEYIVTESDTEALLLEINLIQKNMPKYNIKLKDDKSYPFL
                     KITNESFPRLVITRYIKKNDGLYFGPYPDSYTANEVKKLLDRIFPFKKCKNPINKVCF
                     YYHLGQCCAHTICHTDKAYWDRLIDDVKHFLNGKDDKIIEDLRSKMLAASEEMAFERA
                     AEYRDLISGIATMRTKQRVMSKDLQDRDIFGYYVDKGWMCVQVFFVRQGKLIQRDVNL
                     FPYYNDAEEDFLTYMGQFYQDKQHFIPKEVFIPEAIDEELVAAIVPTKIIKPKRGEKK
                     QLVALATKNARVSLQQKFDLLEKDIKKTSGAIENLGQLLRIDKPVRIEAFDNSNIQGT
                     SPVAAMVVFVDGKPSKKDYRKFKIKTVVGPDDYASMREVLFRRYSRVKKEGLQAPNLI
                     IVDGGVGQVNVAKDVIEKQLGLTIPVAGLQKNDKHQTHDLLFGNPLEVVSLPRRSEEF
                     FLLHRIQDEVHRFAVTFHRQVRRKNSFSSTLDHISGLGPKRKQLLLRHFKTITAIASA
                     TSEEIQALGIPKTVVEAIQQQITDNKNDRSSP"
     gene            14580..15182
                     /locus_tag="ACF4ZO_001562"
     CDS             14580..15182
                     /locus_tag="ACF4ZO_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HFD5487081.1"
                     /translation="MKFLELNKKRHAIKTFNDQPVDYEDLRTAIEIATLAPSANNIQP
                     WKFVVVQEKKAELAKGLPLANKVQVEQAQYVVALFSDTDLALRSRKIARIGVKSLPDD
                     LIGYYMETLPPRFAAFNEVQTGEYLAINAGIVAMNLVLSLTDQKIASNIILGFDKSTT
                     NGILDIDPRFRPELLITVGYSDEKPEPSYRLPVDEVIERR"
     gene            15307..>15753
                     /locus_tag="ACF4ZO_001563"
     CDS             15307..>15753
                     /locus_tag="ACF4ZO_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HFD5487082.1"
                     /translation="MTTIDFKAEVDKRKEAMLADLVDLLRINSERDDRLADDQHPFGP
                     GPVKALEHFLAMAERDGYKTRNIDNYAGDFEFGQGDEVLGIFGHLDVVPAGSGWETDP
                     YEPVIKDNRIYARGSSDDKGPTMACYYALKIIKELGLPVSKKVRFIV"
BASE COUNT         4885 a         2860 c         3333 g         4675 t
ORIGIN      
        1 cccttgataa tgatttggaa attttaccgg ttatcaataa aattgatttg ccagctgctg
       61 accctgagag agtccgtcat gaagtagaag atgtcattgg gcttgatgct tctgaggctg
      121 ttctggcgtc agccaaggct ggtattggga tcgaagagat tcttgagcaa attgttgaga
      181 aggttcctgc tcctacgggt gatgtggatg cgcctttaca agccttgatt tttgactctg
      241 tgtatgatgc ttaccgaggg gtaattttgc aggttcggat tgtgaacggt attgtcaagc
      301 ctggcgataa aatccagatg atgtcgaatg gaaaaacctt tgatgttaca gaagttggga
      361 ttttcactcc taaggcagtt ggacgagatt tccttgcaac gggagatgtt ggttatgttg
      421 cggcttctat caaaacggta gcagataccc gtgtggggga tacggtgact ttagctaata
      481 accctgctaa ggaagccttg catggctaca agcagatgaa cccgatggtc tttgcaggga
      541 tttatccgat tgaatcaaat aaatacaatg acttgcgtga agcgcttgaa aaattacagc
      601 ttaacgatgc cagtttacag tttgaacccg aaacgtcaca agcgcttggc tttggttttc
      661 gatgcggttt tttaggcttg cttcacatgg atgtgattca agaacgtttg gaacgtgaat
      721 ttaacattga tttgatcatg acagcaccat ctgtcgtcta ccatgttcac acaacagatg
      781 aggacatgat tgaagtgtct aacccttcag aatttccagc cccaacacgg gtggctttta
      841 ttgaagagcc ttatgttaaa gcgcaaatca tggtgccaca agagttcgta ggggctgtca
      901 tggaattatc gcagcgcaag cgtggtgatt ttgtgaccat ggattacatt gatgataacc
      961 gtgtcaatgt gatttaccaa atcccgctgg ctgaaattgt ctttgatttc tttgataaac
     1021 tgaaatcctc aacgcgaggc tatgcgagtt ttgattatga catgtcagaa taccgcaggt
     1081 cacaattggt gaaaatggac attcttttga acggtgataa ggtcgatgcg ctcagcttta
     1141 ttgttcataa agaatttgct tatgaacgcg ggaaaattat tgttgagaaa ttgaaaaaaa
     1201 tcattccacg tcaacagttt gaagtgccga tccaagccgc tattggtcaa aaaattgttg
     1261 cgcgttcaga catcaaagcc cttcgtaaaa acgttttagc gaagtgttat ggtggtgacg
     1321 tgtctcgtaa acgtaaattg ctcgaaaaac aaaaggctgg taaaaaacgg atgaaggcta
     1381 ttggttctgt cgaagtccct caagaagcct tcttgagtgt tctctcaatg gatgaggatg
     1441 ccaagaaata accaagccta actgtttatg cttcaaagga aagttcttaa tgggctacat
     1501 gaccaaaaaa ttagttatct cataaaaaag aactttacaa tcatttgcac ataatgttat
     1561 aataatatta tagtgttatc tcattattag gtgagcctac atttaatctt attaaagaga
     1621 aagaggaaac aaaaactgtg aacaaaacaa aacaaaacaa aacaaaacaa aacatagcct
     1681 tctttgtcgc tatggcttaa cgtcagcggc tgctcttttg ctgacctttg gaggtgcaag
     1741 cgcagttaag gcggatgata ataaaagtga tgaagagaaa atagaggcta gaagtagctt
     1801 aataaaaaga cttcatgatg aaataagtgg acaaagcaat aatcaaattc ctaaggttcc
     1861 ggattcaact tacgttggtc ctccaaatat atccgatatc gaaaatgatg tcacggcaat
     1921 ccgtgaatat ttggatagca taaatagttt tttagtagga caaaaaaata gtgataaaaa
     1981 atggaagcta gaattaacgc aaggcattca agatagacta ctggatggta aagacggccg
     2041 agacggtgac aaaggagacc caggcccacg aggcgcaacc ggccctgcag gtcccgctgg
     2101 tccacaaggc ccacgtggtg acaagggcga aactggtgac aaaggagacc agggtccagt
     2161 aggtcccgtc ggtccacagg gcatgccagg tgccaaaggt gaccgctgcg aaaccggtcc
     2221 cgctggccaa aacggtaaag atggtcttcc aggtaaagac ggcaaggacg gccaagacgg
     2281 taaagatggt ctcccaggta aagacggcaa ggatggccaa aacggtaaag atggtctccc
     2341 aggtaaagac ggcaaggatg gccaagatgg taaagatggt cttccaggta aagacggtaa
     2401 ggatggccaa gatggcaaag atggtcttcc aggtaaggac ggccaagacg gtaaagatgg
     2461 cctcccaggt aaagacggta aggacggtca accaggtaaa ccggctccta aaacaccaga
     2521 ggtccctcaa aaaccagata ccgcaccaga tactccaaaa ccccctcaga tccctggcca
     2581 atcaaaagac gtgacacctg cccctcaaaa cccttctaat agaggtctaa acaaaccaca
     2641 aacacaaggt ggtaatcagc tcgcaaaaac accagcagct cacgacacac acagacaatt
     2701 gccagcaact ggcgaaacaa ccaatccatt ctttacagca gctgctgtag ctatcatgac
     2761 gacggctgga gttgtggctg ttgcaaaacg tcaagaaaac aactaatcct ctttttgcta
     2821 cctaactgat ggaaagtaaa actcagagag aacctcaagg ttctctcttt tttgaatcac
     2881 gatagtagct ctaggtataa cgtcttgtct gaggtgctgt gaacaaatca gttaccgctc
     2941 acctcttttt ttggtaaaat gtaagcacta aaacatcaaa aggagttttc catggaaaca
     3001 tcagaagagt taaaacaacg cattggtgat ctttcttacg aggtcaccca gcatgcagca
     3061 acagaatctc cctttacagg ggaatatgat gatttttttg agaagggtat ctatgtcgat
     3121 atcgtcagtg gtgaggtctt gttttcatca ctggataaat ttaattctgg ctgtggttgg
     3181 cctgcctttt caaaacctat tgaaaatcgt atggtcataa accacgatga ctcttcttat
     3241 gggatgagac gagttgaggt taaaagccgt gaagcaggat cgcatttggg gcatgtcttt
     3301 agtgacggcc ccaaagaagc tggaggcttg cgttactgta tcaattcagc agctcttaaa
     3361 ttcattcctt atgagcagat ggaaaaagaa ggctatgccc aatggctcac attgtttgat
     3421 gagacataac agggtctcaa aatgactgaa aaagaagcgt cagtgattcc cataagcact
     3481 ggattggtga ggcgtacggg tcaattttac aagcctttgt aaaaggtcta taatagggaa
     3541 tgaaaaaagg aggttagtat gtcaactcac ttaagaaaac ttccagggct gttactttgc
     3601 ttattgttag ctcttccagc ctggtattta gggcgcttgt ttcctattat tggagctcct
     3661 gtttttgcta ttcttttagg aatgttgtta gccttgtttt atgaacatcg tgacaagact
     3721 aaagagggaa ttagttttac atccaagtat attttacaaa cagcagtggt tttgcttggt
     3781 tttggattaa acctaaccca agttatggca gtgggcatgc agtctttacc gattatcatt
     3841 tcaactattg cgacagctct tttggtagct tatggctcac agaaatggct gcgcatagat
     3901 gtcaatacag ccaccttggt gggtgtaggg tcttccattt gtggggggtc tgctattgca
     3961 gcgacagctc ctgtcattaa ggcaaaggat gacgaggttg ctaaggcaat ttcagtcatt
     4021 tttctcttta atatgttagc agctttgcta tttccaagtc taggacaatt actgggctta
     4081 tctaatgaag gttttgctat ttttgctggg acagctgtta acgacacctc ttcagtaacc
     4141 gcgacagcaa cagcctggga tgcccttcac cattccaata cactagatgg cgcaaccatt
     4201 gtcaaattga ctcgcacctt ggctattctt ccaattactt taggcttatc cctttaccga
     4261 gcgaaaaaag agcacgacat cgttacagaa gaaggcttca gccttaggaa gtcattccct
     4321 cgcttcatcc tcttcttttt attagcttcc ctcatcacga cattgatgat cagtttgggt
     4381 gtttctgccg atgttttcca ttccctaaaa accttatcaa aattctttat cgtgatggct
     4441 atggcggcta tcggtttaaa cacaaacttg gttaaactga ttaagacggg cggtcaggct
     4501 atccttttag gggctatttg ctgggtagct atcacccttg tcagtttagc catgcaatta
     4561 agtttgggca tttggtaatc agacacgaga aatcagtttg actgatttct ttttttgtat
     4621 cttatttgtg tagaattgtc tacattttaa agagaataat gcattttaaa aacgttttca
     4681 tttggtaaaa taaacctatc gttaaaccag tttagtaaag acaactggtt gagataagca
     4741 attaccgttt actcagcggt ttttgttaat agaggaggat aggaatgaaa cgaaaatttc
     4801 tcattgggag tcacggcaga ctagccagtg gtttgcaaag ctctattgac attttagcag
     4861 gtatgggaca ggcacttgaa accattgatg cttatgttga tgatagtgac tacactagcc
     4921 agattgatga ctttatcgct ggggtagcag cagatgagca gggccttatt tttactgatt
     4981 tgttaggcgg cagtgtgaat cagaaaatgg taaccgctgt aatgaacagt ggcaaagaca
     5041 atatcttttt aatcacaaac agtaacttag ccactttatt gtcgttggtg tttttaaaac
     5101 caggcgaagc gcttactaaa gatgaaattg taaccgttat caatgaatcg caagttcagt
     5161 tagtggattt ggtccctgag acaaattcag aagatgactt ttttgattaa tatctaggag
     5221 gaagacaaat gattactcaa attcgtgttg acgaccgttt ggttcacggg caagtggcag
     5281 ttgtatggac caaagagtta aatgcgccac ttttagtagt ggctaatgat gaagctgcaa
     5341 aaaatgaaat cacacaaatg acgcttaaaa tggctgtgcc aaacggcatg aaactgctta
     5401 tccgttctgt tgaagactcg attaagctct ttaatgatcc acgcgcaact gacaagcgga
     5461 tttttgtgat tgtcaattct gttaaagatg cttgtgccat tgctaaagaa gttccagact
     5521 tagaagctgt taatgtggct aatgtggggc gttttgacaa atcagaccca gcaagcaaag
     5581 tcaaagtgac accaagtctt ttacttaacc cagaagaaat ggcagccgca aaggaattag
     5641 tcagtttacc agaacttgat gtctttaacc aagtcttacc atcaaatacc aaggtccatt
     5701 tgagccaatt agtcaactaa agagaggtaa aaaagtatgt tagtaccagc aacaatggca
     5761 gctttagctg tattgatttg ttttggggga aattatttaa ccggtcaaag catgatggaa
     5821 agacccctag tagttggact ggtcacaggt cttcttttag gagatatgaa ggtcggtatc
     5881 ttaatggggg cctctctaga agctcttttc ctaggaaatg tgaatattgg gggtgttatt
     5941 gcagctgagc ctgtaacagc gactgccatg gcaacaacct ttaccattat ttcacatatt
     6001 gaccaaaaag cagccatgac cctagctgtt ccaattggaa tgttggcagc ctttgtggtt
     6061 atgtttttga aaaacgtctt catgaatatc tttgctccaa tggttgataa agctgcagca
     6121 gctaaccatc aaggtaaact agtgatgctc cactatggca cttggattat ctattactta
     6181 atcattgcct ctatttcttt tattggtatt ttagtaggta gtggacctgt taatgccttt
     6241 gtggaacaca ttcctcaaaa tctcatgaat ggcttgagtg ctgcgggagg ccttcttcca
     6301 gctgtcggtt ttgccatgct gatgaaatta ttgtggacca acaaattagc tgttttttac
     6361 ctattgggct ttgtcttaac agcttatttg aaattaccag cggttgcagt tgctgcccta
     6421 ggagcagtta tttgcgtcat tagttcccaa cgtgatctag aattagacgc aattactaga
     6481 ggtgcaatta gtaaacaaac aacctttgac tctaaagaat cagaagagga ggacttcttc
     6541 gcatgacatc acaagataat ttgactaaag aagaccgcaa aatgcttcgc tcagtctttt
     6601 ggcgctcatg gacgatgaat gctagtcgta ctggagcaac acaataccac gcagtagggg
     6661 ttatttacac tttactacca gtcatcaatc gtttttataa gactgataag gataaagcag
     6721 aggcactggt ccgtcataca acatggttca atgccaccat gcacatcaat aactttatca
     6781 tgggtcttgt ggcatcgatg gaaaagaaaa acagtgaaga tcctgatttt gatgctagtg
     6841 ctatcactgc tgttaaggct tcgttgatgg gacctatatc tggagttgga gattccttct
     6901 tctggggaat tttaagggtt attgcggcag gtatcgggat ttccttggca agtgcaggct
     6961 cagccatggg agctgttgtc ttcttactct tgtacaatat tcctgctttt attattcact
     7021 actatagcct ttatggtggt tattctgtag gtgcaggatt tatcaaaaaa ctttacgaat
     7081 ctggtggtat aaaaatcgtc actaaaacct caagcatgct tgggttaatg atggtaggct
     7141 caatgactgc ttcaaatgta aaatttaaaa cgattcttac agttgctgcg aaaggtgcca
     7201 aagaagcagc ttctattcaa gattaccttg accaattgtt tattggtatt gtaccattaa
     7261 tggtaacact agcagctttt tggcttctac gaaagaaagt gaatatcaac tggattatgt
     7321 ttggtatcat gttccttggc attatccttg gacttttagg tatttgctaa taatctccta
     7381 gcaataaagg taagtaagac aagttttctt gttttgctta cctttttcct tttaagatga
     7441 tgagacttgt tttgatgaaa aacgtagtag cattaagaaa tttgttataa tgaaaggagc
     7501 ttaagatgcg aggtgaacag gtggaagaac attttaaaaa acaattacaa gatgatattt
     7561 ctagacattt ttcgtaccaa tcgttaatgt tatcattgtt gctaattggt ctttttatta
     7621 ttttttcatt agcgccacaa caattaggcc tctatcgtga tatcaatgcc actgcaaccc
     7681 gttatcaccg tttgattagc aaacaagaag ccttgctgga tgaattaggg aaaaatagct
     7741 tactaccttt tttaaataaa aagctcaaca ctgctgattt aagcaagcac tattttcatt
     7801 tgcgccatag cagccaaacg tcaccagaac ttttactatt ttcacctaat caaggccttt
     7861 tatttgctag taacccacat ttaggaaatg tttttagtaa atctgtttat attcaagaag
     7921 tcttgagagc agctcatcct ccaaaaacct tgtttaaagt tgctatggat agtgaagatg
     7981 gtcactactt gatgatcatt aagccaatga tagatcaaaa ccaactaaag ggatatgctt
     8041 ttttagtgat gagtggcaaa gatgttcttc atcctacaaa aacattgacg tcagagttgg
     8101 tcattgctga taagctggac aacacgttta cgttttccaa tcgtgagttt atagcatcta
     8161 gtctagataa gatcaacagt cagtatttac accattattt tgtttttcaa gataatcgag
     8221 cctttatcac aagaaaggtt gccttacaag gaggtctttg gctttacatg tataggccct
     8281 tgattccaat ggtatcggtg atgttatttt cacttatttc atcagctgtt atctttgtga
     8341 ttttgcaacg taaatcaagt ggtttagcta accgaattgc agctaaaaat tcaagagcaa
     8401 tcaatcaaat ggttagagat atgagtgcga tctctcggca agaaaaaaga cgtattgacc
     8461 ttgagagtca agatgaattt caatatttat ctgatcaaat caatcaaatg gtagagcgat
     8521 tgcaacagtt acatgataaa acgttagatt tggaaactca aaaattatta tttgaaaaac
     8581 ggatgttaga agctcaattc aatccgcatt tcctctacaa tacgctagaa accattttga
     8641 ttacgagcca ttatgattct gccctaacag aaaaaattgt tatccaattg acaaaattgt
     8701 tgcggtacag tctcacggat tctagcaaac ctgtcttgct caaagatgat ttaagtgtca
     8761 tcgagtctta tttagtgatt aatcaggtgc ggtttgaaga attgcaatat agcattaacc
     8821 tatccccaga ccttgatagt cttgcagtgc ctaaattgtt cttgttacct ttgatagaaa
     8881 atgccatcaa atatggcttg aaagaacgac acgatgtcaa gattaacatt gcttgttatt
     8941 atcaagatga ccacattatt ttttctgtgc gagataatgg ttcgggaatt gatgctcatc
     9001 accaaaaagt gattcgagag caattggaag ctggagagtc acaccatggg ttaattaact
     9061 cttatcgtcg gcttaagtat catttttcag aagtatcctt ggtttttgat caaggtgata
     9121 aacagtttaa tgttagctac catgttaagg agtagtctat gtacaaatta gtcattattg
     9181 aagatgaaca tattattagg aaatggttgc gatacgctat tgattataaa gctttagata
     9241 ttttggtcat tggcgaggct aaagatggca aagaaggagc tgttttaatc aaagagagtc
     9301 aaccagatat cgttttaacc gatattaaca tgcccatcat gacagctttt gacatgtttg
     9361 aagcaacaaa agatcaaact tacgccaaaa ttattttatc tggctatgcc gattttccaa
     9421 atgcaaggtc tgccatacac tacggtgtac ttgaattttt aacaaaaccg attgaaaaag
     9481 cagctctttg ggaatgtctt caaaccatta ttgctaaaat agaaaagcaa aaggggtcta
     9541 atcaaaaaac agatgcttgc gtctatattc ccttacccca gatgactgat cagattcctg
     9601 aagtagtcaa agatattttg gagtgggtac atgctcattt tcaagacaag atcagcacga
     9661 gccgcctagc tcatgactta gggtatagtg agagttatat ctatcaaaat atcaaaaagc
     9721 atcttcagat gcctttaagt gattacatta atcaatatcg gattaatcag gcaattcaat
     9781 tgatgcaaca agaaccagat ttaatggtat atgaaatagc acaagctgta ggtatttatg
     9841 actatcgcta ttttgatagg gtttttaaaa agtatctagg acaaactgta aaggctttta
     9901 aagaagagca ttttatgaaa gataccgata ggagtaagcc atgttaaaac tcaaacgcaa
     9961 atggctatta agctttttgt tagtaataat tattctagca atcgttaaca ttgcaatgta
    10021 tatattctca tcgtcaaaaa aagatagtgc taaagaatta gttatcttga ctcctaatag
    10081 ccaaactatt ttaacaggga ctattccagc ctttgaggaa aagtatgggg ttaaagtaag
    10141 attaatccaa ggtgggacgg gccaacttat tgatcaatta ggtcgaaaag ataaaccatt
    10201 aaacgctgat attttctttg ggggcaatta cactcaattt gaaagccata aagatttatt
    10261 tgaatcctat gtttctccgc aggtttctac tgtcatttca gattaccaat tgcctagtca
    10321 tcgtgcaacc ccatatacga tcaatggcag tgtactgatt gttaataacg aattagcaag
    10381 aggacttcat attaccagtt atgaggattt gctacaacca gctttaaaag gcaaaattgc
    10441 ttttgctgac ccaaatagct catctagcgc tttttcacaa ttaacaaaca tcttactggc
    10501 taaaggaggc tatacgagct cagaagcttg ggagtatgtg aaacgtttat tactgtctat
    10561 gaattctatc agagcaacaa gttcttcaga tgtttacgaa tctgttgcag aaggtaaaat
    10621 gattgttggt ttgacctatg aagacccttg catcaatctg caaaaaagcg gtgcaaacgt
    10681 ttcgattgtt tatccggatg aggggacagt atttgttccg tcatcagtcg ctattatcaa
    10741 aaaagcaaag gcaatgaaag aagctaagca atttattaat tttattttat catcagatgt
    10801 acaaaatgcc tttgggcagt caactagtaa tagacctatc cgacgagatg ctcaaacgag
    10861 tcatgaaatg aaaccattag atgaaattat tactttaaaa gaagattacg gatatgttac
    10921 tagacataag aaaaaaatat tgaataccta taatcgacta catgaagcat tagaaagagg
    10981 aaagtagact ctaggcttgt tgttgctata ctagtagtgt tacaaaatag cgtagtcatt
    11041 ttttgaaatc gatttcataa tctggtagac taagattatc acgaaaagga gataatataa
    11101 tggcttatca aactatttac ccttatacaa atgaagtcct tcatacattt gataatatga
    11161 ccgatcaaga tttggcagat gtccttgaaa gagctcacct tctctataaa aaatggcgca
    11221 aggaagatca tctagaagaa cgtaaagccc agcttcatca agtggctaat attcttcgcc
    11281 gtgaccgcga taaatatgct gaaatcatga ccaaagacat gggaaaactg ttcacagaag
    11341 cccaaggtga agtagatctt tgtgccgata ttgctgatta ctacgctgat aaggcagatg
    11401 agtttttgat gtctacgcca ctagaaacag attctggtca agcttactat ttgaaacaat
    11461 caactggtgt tattctagcc gttgaacctt ggaattttcc ttactatcaa atcatgcggg
    11521 tgtttgcgcc aaactttatt gttggaaacc caatggtttt aaaacacgct tccatttgcc
    11581 cacgctctgc ccaatccttt gaagaattag ttcttgaagc tggtgctgaa gcaggtagta
    11641 ttaccaattt gtttatttct tatgaccaag tatcacaagt gattgctgat aaacgtgtgg
    11701 ttggtgtctg cttgacaggt tccgaacgtg gaggagctag cattgcagaa gaagctggta
    11761 aaaacttgaa aaaaacaacc cttgaattgg gtggcgatga tgcctttatt atccttgatg
    11821 acgcggattg ggatcaatta gagaaggtgc tttacttctc tcgtctctac aatgcaggac
    11881 aagtatgtac ctcatcgaaa cgttttatcg tgcttgacaa agactatgac cgtttcaaag
    11941 aattattaac aaaagtcttc aaaacagcta aatggggtga cccaatggat cccgaaacga
    12001 cgttggcgcc attatcatca gctcaagcta aagcagatgt tcttgaccaa attaagttgg
    12061 ccttggatca tggtgcggag ttggtttatg gtggtgaagc gattgatcat ccaggtcatt
    12121 ttgtcatgcc aaccattatt gctggcctca caaaagacaa ccctatttac taccaagaaa
    12181 tctttggccc agtcggtgaa atctacaaag tatcttctga agaagaagcg attgaagtgg
    12241 cgaatgattc taactatggc cttggaggta ctatctttag tagcaatcaa gaacatgcga
    12301 aagccgtagc tgctaaaatt gaaactggta tgtcttttat caactcaggt tggacaagtc
    12361 ttccagaact cccatttggt gggattaaac attcaggcta tggtcgtgaa ttgagtgagc
    12421 ttggctttac atcttttgtg aatgaacacc ttatctatat tccgaataaa acgaataata
    12481 gcaatactaa agtttgatct agattgttaa aggagatctg ctcgccttaa taaacaatca
    12541 aggcgttaca ctcttctttt ttaaagtcaa aattttaaaa atttgataaa ctagtaacat
    12601 gaacgaactg attaaacata aactagaact cttaccagac agccctggct gttacttaca
    12661 taaagataaa gaaggaacta ttatctatgt cggtaaggcc aagaatttga aaaaacgcgt
    12721 ccggtcctat tttcgtggga gccatgatac caaaacagag ttattagtat ctgagattgt
    12781 agatttcgaa tatattgtaa cagagtcaga taccgaagcg cttttgttgg aaattaactt
    12841 gattcaaaaa aatatgccta agtacaacat caagttaaaa gatgataaat cttatccctt
    12901 tctcaaaatc acaaatgagt cttttcctcg gttagtgatt acaagatata ttaagaaaaa
    12961 tgatggattg tactttgggc cctacccaga ttcttacact gctaatgaag ttaaaaagtt
    13021 attagatagg atttttccat ttaaaaagtg taaaaatcct atcaataagg tctgttttta
    13081 ttaccattta ggccagtgct gtgctcatac catttgtcat acagacaagg cctattggga
    13141 tcgtttaatt gatgatgtta agcacttttt aaatggtaaa gatgacaaaa ttattgaaga
    13201 tcttcgttct aagatgttag cagcttctga agaaatggca tttgaacgtg ccgctgaata
    13261 tcgagatttg atttcaggta ttgccaccat gcgcaccaag cagcgggtga tgagcaagga
    13321 tttgcaagat agagatatct ttggctatta tgttgataag ggatggatgt gtgtccaagt
    13381 tttctttgtg cgtcaaggga aattaattca gcgtgatgtt aacctttttc cctattataa
    13441 cgatgcagaa gaagatttct taacttatat ggggcaattt taccaagata aacagcattt
    13501 catccctaaa gaagtcttta ttccagaagc tattgatgaa gaactggtag ccgctattgt
    13561 gccaaccaaa atcatcaaac ccaaacgcgg tgaaaaaaaa caactggtag ctttggctac
    13621 taagaatgct cgtgttagtc tgcaacaaaa atttgattta ttagaaaaag atatcaaaaa
    13681 aacgagtggt gctatcgaaa atttaggtca gttacttagg attgacaagc ctgtgcgcat
    13741 tgaagccttt gataattcta acattcaagg gacaagtcca gttgcggcta tggttgtttt
    13801 tgttgacggc aaacctagta agaaagatta tcgtaaattt aagattaaaa cagtggtggg
    13861 accagatgat tatgccagta tgagagaagt gctttttcga aggtacagtc gggtgaaaaa
    13921 ggaggggctg caagctccta acttgattat tgttgatgga ggcgttggac aagtcaatgt
    13981 ggccaaagat gtgatagaaa aacaacttgg actcactatt cctgttgcgg gacttcaaaa
    14041 aaacgataag caccagaccc atgatttgct ttttggaaac ccacttgaag ttgtatcgtt
    14101 gccgcgccgt tctgaagagt ttttcttact gcatcggatt caagacgaag tgcatcgctt
    14161 tgcagttaca tttcatagac aagtgcgacg taaaaattct ttttcatcaa cattagatca
    14221 tatttcaggg cttggcccaa agcgaaaaca gttattacta agacacttta aaaccataac
    14281 agcgattgca tcagctacct ctgaggagat tcaagcttta ggtataccta aaacagtagt
    14341 tgaagcaata cagcaacaga taacagacaa taaaaatgat agatcgtctc cttaaataag
    14401 tgttatgttt tcagtactga tgaggtaaaa aggcgctact tgttacgcac gacatttcag
    14461 ttcgttattt tgaaactttc agaaagttgc gaagtgtagt gagtttatga ttttaaaaac
    14521 tattttatgg taaaataaaa tggtattaaa aaaaacagat ttagatagga agttttgaaa
    14581 tgaaatttct agagttaaac aaaaaacgcc atgccattaa gacctttaat gaccagccag
    14641 ttgactacga ggatttgcga acagccattg agattgcaac cttagcacct agtgccaata
    14701 acattcaacc ttggaaattt gtagtcgttc aagagaaaaa agctgagtta gcaaaagggt
    14761 tacctctagc aaataaagtg caggttgaac aggctcaata tgtagtggcg ctattttcag
    14821 acactgattt agctttacgt tctcgaaaaa ttgcccgtat cggtgtcaaa tcgttaccag
    14881 acgacttaat tggttattat atggagactt tgccaccacg ttttgctgcc tttaatgagg
    14941 ttcaaaccgg tgagtactta gctattaatg caggcattgt ggctatgaac ttggtgttat
    15001 ccttgacgga tcaaaagatt gcttccaata ttatccttgg ttttgataag tcaacgacca
    15061 atgggatttt agacatcgat ccgcgttttc gtccagaatt attgattact gttggctata
    15121 gtgacgagaa accagaacca agttatcgtt tgcctgttga tgaagtcatc gaaagaagat
    15181 agagtcagga caattagtta aatgtaatgt ctagatgcgc tactgagcga ccactatttt
    15241 tagactgata ctattttggc ttattttaag ttaaacatta tccctaaaac gaataaggag
    15301 agtataatga caaccattga ttttaaagca gaagttgaca aacgtaaaga agctatgcta
    15361 gcagatttag ttgacctatt acgcattaat tcagaacgcg atgacagatt ggccgatgat
    15421 cagcatccct ttgggccagg tccagttaag gctttggagc atttcctcgc aatggctgag
    15481 cgtgatggct acaaaacgcg taatattgat aactatgcag gtgactttga atttggccaa
    15541 ggtgatgaag tactaggaat ctttggtcac cttgacgttg tgccagctgg tagcggttgg
    15601 gagacggatc cttatgagcc agtgattaaa gacaatcgta tctatgcgcg tggatcttct
    15661 gatgacaaag gaccaaccat ggcatgttat tatgccctca aaattattaa agagttgggc
    15721 cttcctgtgt ctaaaaaggt acggtttatc gtt
//
LOCUS       DAXMQE010000040        15456 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.040, whole genome shotgun sequence.
ACCESSION   DAXMQE010000040 DAXMQE010000000
VERSION     DAXMQE010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15456)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15456)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15456
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.040"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            complement(<1..847)
                     /locus_tag="ACF4ZO_001564"
     CDS             complement(<1..847)
                     /locus_tag="ACF4ZO_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aspartate aminotransferase family
                     protein"
                     /protein_id="HFD5487083.1"
                     /translation="MRENTTLLHGYTVIDEFTGAASVPIYQTSTFHNSELYCPSQKHL
                     YTRFSNPTTEALEDGLACLEKATYAVAYASGMAAISTVLMLLKAGDHVIFPLEVYGGT
                     CQFATAILPNYQIETSFVDMADLATVKASIRPNTRMIYLETPSNPLLKICDISELVQL
                     AKAYGVLTVADNTFMTSLYQEPLAMGVDIVVESVTKFINGHSDVVAGLAATNNEAIYN
                     QLKLFQKNFGAIVGVEDAWLILRGMKTMGIRMEQAVKNAQQLANYLAKHPKVLKVHYP
                     GLDSHP"
     gene            1332..1598
                     /locus_tag="ACF4ZO_001565"
     CDS             1332..1598
                     /locus_tag="ACF4ZO_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpoV family signaling peptide"
                     /protein_id="HFD5487084.1"
                     /translation="MKNKLFLVALATVTVLGPSLANPHHGTVHTTEYCTYVTGKPEVG
                     GCYERKDGMPIEENIIKKSNDFSLLNWFWEIITNWWSKITGYFS"
     gene            1783..1938
                     /gene="spoV"
                     /locus_tag="ACF4ZO_001566"
     CDS             1783..1938
                     /gene="spoV"
                     /locus_tag="ACF4ZO_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence-signaling peptide SpoV"
                     /protein_id="HFD5487085.1"
                     /translation="MKKKLSLFMIATAAVAGLSLATLGNHQTVSANDASFYGQNAPDS
                     WLLYTVW"
     gene            2321..2563
                     /locus_tag="ACF4ZO_001567"
     CDS             2321..2563
                     /locus_tag="ACF4ZO_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpoV family signaling peptide"
                     /protein_id="HFD5487086.1"
                     /translation="MKKKLSLFMIATAAVVGLSLATPKNQTVSANEAVATQACADGTN
                     CCGYNFYGYCRPISWLFYKTKHLLMGDQPTTDIVTK"
     gene            complement(2702..4417)
                     /gene="slo"
                     /locus_tag="ACF4ZO_001568"
     CDS             complement(2702..4417)
                     /gene="slo"
                     /locus_tag="ACF4ZO_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_095889392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin streptolysin O"
                     /protein_id="HFD5487087.1"
                     /translation="MSNKKTFKKYSRVAGLLTVALIIGNLVTANAESNKQNTASTETT
                     TTNEQPKPESSELTIEKAGQKMDDMLNSNDMIKLAPKEMPLESAEKEEKKSEDKKKSE
                     EDHTEEINDKIYSLNYNELEVLAKNGETIENFVPKEGVKKADKFIVIERKKKNINTTP
                     VDISIIDSVTDRTYPAALQLANKGFTENKPDAVVTKRNPQKIHIDLPGMGDKATVEVN
                     DPTYANVSTAIDNLVNQWHDNYSGGNTLPARTQYTESMVYSKSQIEAALNVNSKILDG
                     TLGIDFKSISKGEKKVMIAAYKQIFYTVSANLPNNPADVFDKSVTFKDLQRKGVSNEA
                     PPLFVSNVAYGRTVFVKLETSSKSNDVEAAFSAALKGTDVKTNGKYSDILENSSFTAV
                     VLGGDAAEHNKVVTKDFDVIRNVIKDNATFSRKNPAYPISYTSVFLKNNKIAGVNNRT
                     EYVETTSTEYTSGKINLSHQGAYVAQYEILWDEINYDDKGKEVITKRRWDNNWYSKTS
                     PFSTVIPLGANSRNIRIMARECTGLAWEWWRKVIDERDVKLSKEINVNISGSTLSPYG
                     SITYK"
     gene            complement(4441..4926)
                     /locus_tag="ACF4ZO_001569"
     CDS             complement(4441..4926)
                     /locus_tag="ACF4ZO_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD glycohydrolase inhibitor"
                     /protein_id="HFD5487088.1"
                     /translation="MYKVPKGLEHYQKMFQKEVTVNDLKKYLIGSDKEYRITRRDSYM
                     GDISDPEVILEYGVYPAFIKGYTQLKANIEEALLEMSNSGQALDIYQAVQTLNAENML
                     LNYYESLPFYLNRQSILANITKALKDAHIREAMAHYKLGEFAHYQDTMLDMVERTIET
                     F"
     gene            complement(4931..6286)
                     /gene="nga"
                     /locus_tag="ACF4ZO_001570"
     CDS             complement(4931..6286)
                     /gene="nga"
                     /locus_tag="ACF4ZO_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotine adenine dinucleotide glycohydrolase"
                     /protein_id="HFD5487089.1"
                     /translation="MRNKKVTLAHIVAKTSVAIALAGAMGSSLLANSTTYAVSGKENK
                     KSDVKYETTKVMEANATSSKEDNHVMHTLDGSMSTVWEENSPGGGVGEVLSYKFASPM
                     RIGRILIVNGDTSSKENYYKKNRIAKADVKYYNGNKLVLFQKIELGDTYTKKPHHIEI
                     DKKLDVDRIDIEVTEVHQGQNKDILALSEVTFGNMERDLFEKKFKEIKDKWVTDKQAD
                     EFIETADKYADKAVQMSAVASRAEYYRMYVSRKYQYKKEFVEKLKQVYKESGASHVTS
                     KKDLMLAFDDAKRKSTIGRQENGLFVTSFAEDMALLFTDQGKLKSADQIENIKGVDSG
                     KYSDGVYQYEYDSELTKNIDKLGYIRTASGDTPGANSLNIPGCQTWSGKHIENSESEL
                     IFPSISVKDLKSKAVLAEIDAKGYFEIIDPTIIAPNGDHKKVTGRFKIKKMQDRMQDR
                     K"
     gene            complement(6658..7197)
                     /gene="nusG"
                     /locus_tag="ACF4ZO_001571"
     CDS             complement(6658..7197)
                     /gene="nusG"
                     /locus_tag="ACF4ZO_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0032784 - regulation of DNA-templated
                     transcription elongation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HFD5487090.1"
                     /translation="MLDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEI
                     PTQTVNVEKNGQTKEIEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKP
                     TPLLEEEIRAILLSMGQTIDVFDTNIKEGDVVQIIDGAFMGQEGRVVEIENNKVKLML
                     NMFGSETVAEVELYQIAEL"
     gene            complement(7370..8413)
                     /locus_tag="ACF4ZO_001572"
     CDS             complement(7370..8413)
                     /locus_tag="ACF4ZO_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HFD5487091.1"
                     /translation="MNKKVMSLGLVSTALFTLGGCTNNSSKQTTDNSLKIAMITNQTG
                     IDDKSFNQSAWEGLQAWGKENKLEKGKGYDYFQSANESEFTTNLESAVTNGYNLVFGI
                     GFPLHDAVEKVAANNPDNHFAIVDDVIKGQKNVASITFSDHEAAYLAGVAAAKTTKTK
                     QVGFVGGMEGDVVKRFEKGFEAGVKSVDDTIKVRVAYAGSFADAAKGKTIAAAQYAEG
                     ADVIYHAAGGTGAGVFSEAKSINEKRKEEDKVWVIGVDRDQSEDGKYTTKDGKSANFV
                     LTSSIKEVGKALVKVAVKTSEGQFPGGQITTFGLKEGGVSLTTDALTQDTKKAIEAAK
                     KAIIEGTITVPEN"
     gene            complement(8740..10032)
                     /locus_tag="ACF4ZO_001573"
     CDS             complement(8740..10032)
                     /locus_tag="ACF4ZO_001573"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000205037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004019 - adenylosuccinate synthase
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HFD5487092.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSADAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPQKISVIGNGVVVNPKSLVKELAYLHDEGVTTDNLRISDRA
                     HVILPYHIQLDQLQEDAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFAERL
                     RINLAEKNRLFEKMYDSTPLDFDAIFEEYYAYGQEIKQYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDAVKICVAYDLDGERIDYYPASLEQLKRCKPIYEELPGWQEDITGVRSLDELPEN
                     ARNYVRRIGELVGVRISTFSVGPGREQTNILESVWASI"
     gene            10470..11348
                     /locus_tag="ACF4ZO_001574"
     CDS             10470..11348
                     /locus_tag="ACF4ZO_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5487093.1"
                     /translation="MIRKYDRTSTKKKSLNWIWLIIAFFMISSFIGGSSFTESLLDIL
                     PAIAIGGTGYAIFRVRSHQKRLAKAKIAKQLEDLKAKIQLADRKVRLLDTYLADHDDF
                     QYNVLAQQLLPQLSDIKAKAITLKDQLDPKIYRRITKKANDVESDITLQLETLQIATT
                     LNPQPLKTPSPNLINKAPELKPYYDNIQTDHQAILAKIQGADNQEELLALHEANMRRF
                     EDILTGYLKIKEEPKNYYNAAARLEQAKQAIQQFDEDLDETLRQLNESDLKDFDISLR
                     IMQGATQRRTTHHQKD"
     gene            11361..12623
                     /locus_tag="ACF4ZO_001575"
     CDS             11361..12623
                     /locus_tag="ACF4ZO_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HFD5487094.1"
                     /translation="MADFNFDIDQIADNAVVKTDKTTDIISDLPTDTNGQISFFEKLS
                     ADQQTAITAKAPALVDTFLADQNALLDFGQSAVEEVNATVDHILAEQKKLQIPQVDDL
                     LKSTNRELNGFIAKYKDATPVDLDKKPNFLQKLFKQSRDTLQEFYFDSQNIEQKMDSM
                     AAAVVKQEDTLARNIVSAELLIEDNTKSIEHLVGVIAFIEASQKEASQRAAALQKDLK
                     TKDSTTPDYQIKADLLARTTEVINTLEQQHTEYLSRLYVAWATTPQMRNLVKVSSDMR
                     QKLGMLRRNTIPTMKLSIAQLGMMQQSVKSGMTADAIVNANNAALQMLAETSKEAIPA
                     LEQSAQSPTLSMKSVTSLAESLVAQNNGIIAAIDHGRKERAQLESAIIRSAETINDSV
                     KLRDQNIVQALLSEGKETQKTIDKTTHA"
     gene            complement(12743..13369)
                     /locus_tag="ACF4ZO_001576"
     CDS             complement(12743..13369)
                     /locus_tag="ACF4ZO_001576"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HFD5487095.1"
                     /translation="MARLNVKPTRMELSNLKNRLKTATRGHKLLKDKRDELMRRFVDL
                     IRENNELRQTLEKELAANMKEFVLAKASENSLMVEELFAVPVHEVTLWIDIENIMSVN
                     VPKFHVQSNTAREQEQGEFAYSYLSSNSEMDNTIQKTKELLEKLLRLAEVEKTCQLMA
                     DDIEKTRRRVNGLEYSIIPQLEETIHYIELKLEEAERASLVRIMKITS"
     gene            complement(13414..14829)
                     /locus_tag="ACF4ZO_001577"
     CDS             complement(13414..14829)
                     /locus_tag="ACF4ZO_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HFD5487096.1"
                     /translation="MSVLKEYRTVSEVVGPLMIVDQVAGVHYNELVDITLHNGERRKG
                     QVLEVQGDKAMVQLFEGSTGINLAKTKVRFTGHPLELAVSEDMVGRIFDGMGQPIDGG
                     PELIPEKYLDIDGQAINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHN
                     ELAAQIARQATVLNSDDNFAVVFAAMGITFEEAEFFMNDLRETGAIDRSVLFINLAND
                     PAIERIATPRIALTTAEYLAYEKGMHVLVIMTDMTNYCEALREVSAARREVPGRRGYP
                     GYLYTNLSTLYERAGRLIGKKGSVTQIPILTMPEDDITHPIPDLTGYITEGQIILSQE
                     LYKNGFRPPINVLPSLSRLKDKGSGEGKTRQDHAATMNQLFAAYAQGKQAKELAVVLG
                     ESALSETDKLYVAFTNRFEEEYINQGFYTNRSIEESLDLGWELLSILPRTELKRIKDD
                     MLDRYLPKADTTMTKVFVAND"
     gene            complement(14830..>15456)
                     /locus_tag="ACF4ZO_001578"
     CDS             complement(14830..>15456)
                     /locus_tag="ACF4ZO_001578"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017275.1"
                     /note="produces ATP from ADP in the presence of a proton
                     gradient across the membrane; the A subunit is part of the
                     catalytic core of the ATP synthase complex; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HFD5487097.1"
                     /translation="TITAIGAVSPPGGDISEPVTQNTLRIVKVFWGLDAPLAQRRHFP
                     AINWLTSYSLYQDDVGSYIDRKQQSNWSNKVTRAMAILQREASLEEIVRLVGLDSLSE
                     QDRLTMAVARQIREDYLQQNAFDSVDTFTSFPKQEAMLTNILTFNEEASKALSLGAYF
                     NEIMEGTAQVRDRIARSKFIPEENLEQIKGLTQKVTKEIHHVLAKGGI"
BASE COUNT         4603 a         3267 c         2733 g         4853 t
ORIGIN      
        1 taggatgact gtctaagcca gggtaatgta ccttaagaac tttggggtgc ttcgctaaat
       61 agttagcgag ctgctgagca ttttttaccg cttgttccat acggatcccc atagttttca
      121 tgccacgaag aatcagccaa gcgtcttcga ccccaacaat tgctccaaag tttttttgaa
      181 aaagcttgag ctggttgtag atagcctcat tattggtagc agctaaacca gctaccacat
      241 cactatgacc attgataaat tttgtcacac tttctaccac aatatccaca cccatagcta
      301 agggttcttg atacaaactt gtcataaagg tattatcagc cacagttagc acaccataag
      361 ctttggcgag ttgcacaagc tctgaaatat cacaaatttt caagagcgga tttgacggtg
      421 tctctagata aatcatacgt gtattaggcc tgatacttgc ttttactgtt gctaaatcag
      481 ccatatctac aaagcttgtt tcaatctgat aattgggtaa aatagctgtc gcaaattgac
      541 aagtccctcc atagacctcc aatgggaaaa tcacatgatc tccagctttt aagagcatca
      601 aaacagttga aatagcagcc ataccagatg cataagccac cgcataagtc gctttttcta
      661 aacaggctaa cccgtcttct aaagcttcag tcgttgggtt tgaaaagcgt gtgtacaaat
      721 gtttttgact aggacaatac agttctgaat tgtggaacgt cgaagtctga tagatgggaa
      781 ctgaagctgc tcctgtaaac tcgtcaataa ccgtatagcc atgtaataag gtcgtatttt
      841 ctctcatttc gtgcacctcc gcaatagcgt taactccaat gaactctctt ttagacaatg
      901 gtcccacccc aatggttgca caaaccaaaa agctcttcaa aaaagcgtga tctgctaacc
      961 tataagaaaa gtagtgggca ccttttaaat ggataatgaa tttttccaac aatatcattt
     1021 ttagatcgat tacgtttatt atacaacctt tagctaagtt tgcaagccct tttatcatct
     1081 ttgaccaagc tgccaacacc tctccagcaa gttaaagtat ggctaccttt ggccccatcg
     1141 tctcaaaagc tcagattatc acactgacag tcctactttg catcgtcacc tactcaatat
     1201 ggcaatactg ccatcaaaat ttcattaaaa agtcacaatt tatttcattt aatgagaaac
     1261 agaacttgtt ttcaccatgc gtcttataag tacactgcta aagtactatt tatttttagg
     1321 agagaaatat agtgaaaaac aaattatttt tagttgccct tgcgaccgta actgtcctag
     1381 ggccgtcttt agcaaaccct catcacggga ccgtgcatac gactgagtat tgtacctatg
     1441 tgactggaaa accagaggta gggggttgct atgagagaaa agatggtatg ccaatagaag
     1501 aaaacattat caaaaaaagc aacgattttt cccttcttaa ctggttttgg gagataatta
     1561 ccaattggtg gtcaaaaata acaggttatt tttcgtaata ctagtcacag catagtctac
     1621 cgctaactat taaaataaaa aaccgtctcg tggcggtttt ctaatcctag gtcgccacac
     1681 ttcttattca gataaataat aataaaaaca ttaaaataac acttgattta ttaacgaaaa
     1741 gttagtataa tatagtcata ctacaaatta aaggagttat ctatgaaaaa gaaattatct
     1801 ttatttatga tcgcaactgc tgctgttgca ggccttagcc ttgcaacact aggaaaccac
     1861 caaactgttt cagcaaatga tgctagtttc tacggacaaa atgctcctga cagctggtta
     1921 ctttacactg tatggtaagc ctaataccgt aacatagaag ctatcttctt cgtaagacta
     1981 cggttatgaa aagcctaagg ctgcttatgc agccttaggc tttttgattg gcaaaaacgt
     2041 tttagccaat gacccctcaa ggtaaaacag aaaaggagac aaacccaaaa cacaagtcgt
     2101 aacagttgct agctaaccag caccaaaaaa gctgtaatac ctcaaatata atgataacca
     2161 gattaatatt attaatcatt aatgtgattt atataagata aagaaatact ttagtcttgg
     2221 ctttctttgc ctttttcggt caaacatatc acaaaaagat taaaatatga tattgaatca
     2281 ttaatagaat atgagtataa tataatttaa ggaattgcaa atgaaaaaga aattatcttt
     2341 atttatgatc gcaactgctg ctgttgtagg ccttagcctt gcaacaccaa aaaaccaaac
     2401 tgtttcggca aatgaggcag tagctactca agcatgtgca gatggaacaa attgctgtgg
     2461 ttacaatttc tatggatatt gcagacctat cagctggtta ttctataaga caaaacactt
     2521 gttgatggga gatcagccta ctacggatat agtcacaaaa tagtgagaca acagttataa
     2581 aaaagcttgt ctatgaaggt atctcataga caagcttttt tctgtatttg tgagaggagt
     2641 aggcacaaag cctcaagaga taagcagcat caaggtgctt gacgaacctc ttgaaccagt
     2701 cctacttata agtaatcgaa ccatatgggc tcaaggttga tcctgagatg ttgacattga
     2761 tttctttaga tagtttcaca tctctttcgt cgatcacttt tcgccaccat tcccaagcta
     2821 agccggtgca ctctctagcc atgatacgga tatttcgtga attagctcct agtgggataa
     2881 ctgtgctaaa tggtgatgtc ttactatacc agttgttgtc ccaacgtcgt tttgtaatca
     2941 cttcttttcc tttgtcatca taattgattt catcccaaag gatttcatat tgagcaacat
     3001 acgcgccttg atgagacagg ttaatttttc cactagtgta ctcggtagat gttgtttcaa
     3061 cgtattcagt tctgttattg acacccgcaa ttttattatt tttaaggaaa acactggtgt
     3121 atgaaatagg ataagctggg ttttttctac tgaaggtagc attgtctttg ataacgtttc
     3181 taataacatc aaagtctttt gtgaccacct tattgtgctc tgcagcatct cctcctaaaa
     3241 cgacagctgt aaatgagcta ttttctaaga tatcagagta ttttccattc gttttaacat
     3301 ctgttccttt tagagctgca ctaaaggccg cttcaacatc attactttta gaacttgttt
     3361 ctagtttgac aaaaacagtt cgaccatagg ctacgttact cacaaagagt ggcggagctt
     3421 cattgctgac accttttcgt tgcaaatctt taaaggtcac tgatttatca aacacatccg
     3481 caggattatt aggaaggttt gctgatacgg tgtaaaaaat ttgcttgtat gctgcaatca
     3541 tcaccttctt ttcacctttt gaaatcgact tgaaatcaat gcctaaagta ccatctaaga
     3601 ttttgctatt aacatttaga gctgcttcaa tctgtgactt agaatatacc attgattcag
     3661 tatattgtgt tctggcagga agcgtattac caccagaata attatcatgc cattggttaa
     3721 caagattatc aatagctgtt gaaacattgg cataggtagg gtcattgacc tcaaccgttg
     3781 ctttgtctcc catacctggt aaatcaatat ggattttttg tgggtttcgc ttggtgacta
     3841 ccgcgtctgg tttgttttcg gtaaaacctt tattagccag ctgaagggct gctggatagg
     3901 tcctatcagt gacagagtca ataatggaaa tatcgactgg tgtagtgttg atattttttt
     3961 tctttctttc aatgacaata aatttatcag ctttcttaac gccttcttta ggaacaaaat
     4021 tttcaatggt ttcaccattt ttagcaagta cttcaagctc attataattt agtgaataaa
     4081 tcttgtcatt gatttcttca gtgtgatctt cttcgctctt ttttttgtct tctgactttt
     4141 tttcttcttt ttctgcagat tctagtggca tttctttggg agcaagctta atcatatcgt
     4201 tagagttaag catatcatcc attttctgac ctgctttttc gatagttagc tcactacttt
     4261 ctggttttgg ttgctcattt gtcgttgtgg tttctgtact agcagtgttt tgtttgttcg
     4321 attcagcatt agcagtaaca agattaccaa tgataagagc taccgttagt agcccagcga
     4381 cgcgactgta ttttttaaat gtttttttat tagacatgtc cttcatacct ttttatcatt
     4441 ctaaaatgtt tctattgttc tttcgaccat atcaagcata gtatcttgat agtgagcaaa
     4501 ttctcctaat ttgtaatgtg ccatagcctc tctaatatgc gcatctttta acgctttggt
     4561 tatattagct agtatgcttt gacggtttaa ataaaatggc aagctttcgt aataatttaa
     4621 taacatgttt tcagcgttta gggtttgaac cgcttggtaa atgtctaatg cttgaccgct
     4681 atttgacatt tctaataatg cttcttcgat gttagctttc aattgggtat agccttttat
     4741 gaaagcaggg taaaccccat actctaaaat aacttctgga tcagaaatat ctcccatata
     4801 agagtctctt ctagtgatac gatactcttt gtcactacct atcaagtatt tttttaaatc
     4861 attaacagtt acttcttttt gaaacatttt ttggtaatgt tctaaaccct ttggcacctt
     4921 atacatattg ttacttccta tcttgcattc tatcttgcat tttcttaatt ttgaagcgac
     4981 cagttacttt tttatggtca ccatttggag caatgatggt aggatcaata atttcaaaat
     5041 accctttggc atcaatctct gctaagacag ctttagattt tagatcttta acactaatcg
     5101 atgggaaaat taattcactt tctgaatttt caatgtgttt tcctgaccac gtttggcaac
     5161 caggaatgtt gagcgaattt gctccaggag tatctccgct agctgttcgg atatagccta
     5221 gcttatcaat gttttttgtt agttcagaat cgtactcata ttgataaacc ccatcactat
     5281 attttccgct atcgacacct tttatatttt caatttggtc agctgatttt aacttacctt
     5341 gatcagtaaa gagcaatgcc atatcttcag caaaacttgt cacaaaaaga ccgttttctt
     5401 gtcgaccaat cgttgacttt cttttagcat catcaaaagc taacatcaaa tcttttttac
     5461 ttgtaacgtg agaagctccg ctttctttgt agacttgttt tagtttttca acaaactctt
     5521 ttttgtactg gtatttgcgg ctaacataca tccggtaata ctcagcacgt gacgcaacag
     5581 cagacatctg aacagcttta tcagcatact tatcggcagt ttcaataaac tcatctgctt
     5641 gtttatctgt tacccattta tctttaattt ctttaaactt tttttcaaaa agatcgcgtt
     5701 ccatattgcc aaaagtgacc tctgacaagg ctaaaatatc cttgttttgt ccctgatgga
     5761 cctctgttac ctcaatatca atacgatcaa catctaattt tttatcaatc tcaatgtgat
     5821 gcggtttttt agtgtaggtg tcgcctaatt caattttttg aaagaggacc aatttattcc
     5881 cgttatagta tttaacatca gcctttgcaa ttctattttt cttgtagtaa ttctccttgc
     5941 tagatgtatc tccattaaca attaaaattc tcccaatacg catcggggac gcaaacttgt
     6001 aggaaagtac ctcaccaaca ccaccaccag gtgaattttc ctcccagaca gtactcattg
     6061 agccgtctaa tgtgtgcatg acatgattgt cttctttaga ggaagtggcg ttagcttcca
     6121 taaccttggt cgtttcatat ttgacatcgc tttttttgtt ttctttgcca ctaacagcgt
     6181 acgttgtgct attagctaat aaactgctac ccattgctcc agccaaagca atagcaacac
     6241 ttgtctttgc gacaatatga gctaatgtta cttttttgtt tctcatgtaa accaccttat
     6301 attattttta agtaaactat acattaacaa atagtctttg tcaatgcgat ttattaacat
     6361 cgttttaggc ttttctatca aaaaaatgaa cacaaaaaaa acaagtagtc aactgttaca
     6421 agtttcaagg ggatatttcc atcttattat cacagaatct tcacatctgt tctatttaaa
     6481 ccagattaaa agtactagtt aaatatttga tagtagcacc gttatcagta atagatctgt
     6541 taattatctc tgattacaat gatgttaaca atagtcatcc gtttgtttgt acacacgctt
     6601 cactgccaac taaaaaaggt ctgatggtaa tatttatacc atcagacctt tgagagccta
     6661 tagttctgca atttgataaa gttcaacttc tgctactgtt tcagagccaa acatgttgag
     6721 catcagcttc actttgttgt tttcgatttc taccacacga ccttcttgtc ccataaaggc
     6781 accgtctatg atctgaacca catcgccttc tttgatattg gtatcaaaga catcaatggt
     6841 ttgacccata gacaacaaga tagcacggat ttcttcttca agaagtggtg ttggttttga
     6901 tcggttcccg tgtgatccca caaaacctgt aacgtttggt gtgttacgca caacaaacca
     6961 agcttcatct gtcatgacca tttcaaccaa gacataccct ggaaagcgat tttcttcgat
     7021 ttctttggtt tgcccatttt tttcaacgtt aaccgtttgt gtcggaattt cgacgcgcaa
     7081 aatattgtcc aacatgttat aggtttgggc acgttgcaag aggttttctt ttactttgtt
     7141 ttcgtagcct gagtaagttt ggaggacgaa ccagccctta tcaaatgaat ctagcatgat
     7201 gtttcctttc attataaaaa agcccttttt ttggcttttg cgctgttttc tatcaccttc
     7261 attataataa aagacagggc tgctgtcaac gtatctgtgg agctacttga cacctttatt
     7321 aaaaagtcca aagtcggttc gtgacgactc tggacggtat tgtacagttt tagttttcag
     7381 gaactgtgat ggttccttcg ataatcgctt ttttagcagc ctcaatagct tttttagtgt
     7441 cttgtgtcag agcatccgtt gtaaggctaa caccaccttc ttttaaacca aaagtggtta
     7501 tttgaccacc tgggaattgg ccttctgagg tttttacggc tacttttact aaagcttttc
     7561 cgacttcctt gatacttgag gtcaaaacaa aattagctga cttgccatct tttgtggtgt
     7621 attttccatc ttcactttgg tcacggtcaa caccaataac ccaaacctta tcttcttctt
     7681 tacgtttttc gttgatagac ttagcttcgc taaagacacc cgcccctgtg cctcctgctg
     7741 catgataaat aacatctgcg ccttcagcgt attgagcagc tgcaatcgtc ttgcctttgg
     7801 cagcatctgc aaaagagcct gcataagcaa ctcttacttt gatggtatca tctactgatt
     7861 tcacaccagc ttcaaaacct ttttcaaagc gcttgacaac atctccttcc ataccaccta
     7921 caaaaccaac ttgcttggtt tttgtcgttt tagctgctgc aacaccggct aggtatgccg
     7981 cttcatggtc tgaaaaggtg atacttgcaa catttttttg acctttaatc acatcatcca
     8041 caattgcaaa atggttgtca ggattgtttg cggctacttt ttctacagcg tcatgtaatg
     8101 gaaatccaat cccaaaaaca agattataac cattggttac tgctgactca aggtttgtgg
     8161 taaactctga ttcattggct gattggaaat aatcatagcc ttttcctttt tcaagtttat
     8221 tttcttttcc ccaagcttgt aatccttccc aggctgactg gttaaatgac ttgtcatcaa
     8281 tacccgtctg attagtgatc atagcgattt ttaatgaatt gtcagttgtt tgtttagagg
     8341 agttattggt gcagcctcct aatgtgaata gggcagtcga aacaagacca agtgacatta
     8401 cttttttgtt catgtgaaaa tgaacctcct aaatgtttaa tcctaaagtg atgtgtcatt
     8461 gttaacgttc tacttatgct ctagaacgaa aagtttagta tatcaaaaaa atcagtttta
     8521 tcctactatt tttgctgaaa aatctctttt tcaccaaaat gaccgaacga taaagtgaaa
     8581 tcaactggca aaacccgtta tctcctcaaa aatcacctct taaggagata agtcaacgac
     8641 aaaactcaag ctactagtaa tagcatgact aactatacaa tccaacaagt ggtaaaaaga
     8701 gctggaaacg ctatccaact ctttgtcata ctagacacct tagatagatg cccagaccga
     8761 ctcaagaata ttggtctgtt cacgccctgg accaactgag aaggttgaaa tgcgaacacc
     8821 aaccaattct ccaatacgac gaacgtagtt gcgggcattt tcaggcagct catcaaggct
     8881 acgaacacct gtaatgtcct cttgccagcc tggtaattct tcgtagattg gtttgcaacg
     8941 tttgagttgt tcaaggcttg ctgggtaata gtcaatacgt tcaccatcta aatcgtaagc
     9001 cacacaaatc ttaaccgcat caagccctga aagaacatca attgaattca gagagaggtt
     9061 agtaatacct gatacacgac gactgtggcg catgacaacc gaatcaaacc aacccacgcg
     9121 acgtggacga ccggtcgttg tcccgtactc atgacccact tcacgaatgc gctcacccac
     9181 ttcatcaaag agttctgtag ggaatggccc atcaccgaca cggcttgtgt aggctttaca
     9241 gacaccaact actttgttga ttttacttgg gccaacacca gaaccaatgg ttacaccacc
     9301 agcaactggg tttgaagacg ttacaaatgg gtaagttcct tggtcaatat caagcataac
     9361 cccttgtgca ccttcaaaaa gaacacgttt accggcatca agtgcatcat ttaaaattac
     9421 agaagtatct gtcacatatt gcttgatttc ttgaccgtaa gcatagtatt cttcaaaaat
     9481 agcatcaaaa tcaagaggtg tactgtcata cattttttca aataaacggt ttttctcagc
     9541 taaattaatg cgtaggcgct ctgcaaagat atccttatcc agtaaatctg cgatacggat
     9601 accaactcga gcagctttat ccatataagc tggaccaatc cctttaatag ttgttccgat
     9661 tttattgtca ccttttgcat cttcttgcag ttgatccagc tggatatgat aaggtaaaat
     9721 gacatgagct cggtctgaaa tgcgaaggtt atctgtcgtc actccttcat catgcaggta
     9781 cgccaactct ttgaccaaag atttggggtt gaccacaacg ccattaccaa taacggaaat
     9841 tttttgcggg aagaaaattc ctgatgggat caagtgaagt ttaaacttct taccatcaat
     9901 cacgatcgta tgaccagcat tatcaccacc ttgatagcgt gcaattactt ctgcatccgc
     9961 tgacaagaaa tcagtgattt tacctttacc ttcgtcaccc cactgggtac caacaacaac
    10021 tacagatgtc atatcattgt cctaactttc tgaaacactt attctcaata aaaatcatag
    10081 gcaagctaac cactgcttaa aaaccaaaaa gaaggtcaga tctgtaagat cagcaatgta
    10141 gctcttgata tttaaagaaa acaggcagga atctcacctg ctagcatata tcttacaact
    10201 tattatagca aaaaatgatt ttttctgcta gatttcttag cattattaag gaaaaagaga
    10261 aactcttttt ttaaccatga taaacaagcc taaaaaaacg aacattataa gagaaaagct
    10321 tttaacctcg tttctcctaa actttagcag ggttaaacga ttctcttaaa acattagctc
    10381 ttttctttca gaaatagcgg ttttaaggta aaataatagt aagttacctc tatgagatag
    10441 ccagtaaaaa catatcgagg aaatatcaca tgattagaaa gtatgaccgc acgagcacaa
    10501 aaaagaaatc actaaactgg atttggctaa tcatcgcttt ttttatgatt tcaagcttta
    10561 taggtggctc ttcttttact gagtcacttc tagacatttt gcctgccata gccattggtg
    10621 gtacaggtta tgctattttt cgtgttagat ctcatcaaaa gcggctagca aaggccaaga
    10681 ttgccaaaca attagaagat ctaaaagcaa aaattcagct agctgatcgt aaagttcggc
    10741 tgttagacac ttatctggca gaccatgatg acttccaata taacgtactt gctcagcaat
    10801 tattaccaca acttagtgac atcaaagcaa aagctattac gttaaaagac cagttagatc
    10861 ccaaaattta tcgtcgtatc accaaaaaag ccaatgacgt tgaaagtgat attacccttc
    10921 aactcgaaac actgcagatt gccacaactc ttaaccctca gcctttgaaa accccatctc
    10981 ctaatcttat taacaaagca cctgagctca aaccgtatta tgataatatt cagacagatc
    11041 atcaagctat ccttgctaaa atccaaggag ccgacaatca agaagaattg cttgcgctgc
    11101 atgaagctaa catgaggagg tttgaggata tcttaacagg ctacttaaaa atcaaagaag
    11161 agcctaaaaa ttactataac gctgctgctc gtttagaaca agccaaacaa gctatccaac
    11221 aatttgatga agatcttgac gaaacccttc gtcaactcaa tgaaagtgat cttaaagatt
    11281 ttgatattag ccttcgaatc atgcaaggtg ctactcaaag acgaacaacg catcaccaaa
    11341 aagactaaag gagtcccttt atggcagatt ttaattttga cattgaccaa attgctgaca
    11401 atgctgttgt caaaaccgat aaaaccaccg atattatctc agacttacca actgacacaa
    11461 atggccaaat ctcttttttt gagaaactaa gtgctgacca gcagacagct attactgcca
    11521 aagccccggc attggtagat acctttttgg cagaccaaaa tgcgctactt gattttggtc
    11581 agtctgctgt tgaagaggtc aatgcaacgg tcgatcatat cctggccgaa caaaagaagt
    11641 tacagattcc tcaggttgat gatcttttaa aatcaaccaa tcgtgaactc aatggtttta
    11701 tcgctaaata caaggatgcc acacctgtgg accttgataa aaagccaaac tttcttcaaa
    11761 aactctttaa acaaagccgt gataccctgc aagagtttta ttttgattct caaaacattg
    11821 agcaaaaaat ggatagtatg gctgcagcgg ttgtcaagca agaagatacc ttagctcgca
    11881 atattgtctc agcagaattg ttaattgaag ataatactaa gtccattgaa catttggtag
    11941 gcgtcattgc ttttatcgaa gctagtcaaa aagaagctag tcagcgcgct gcggctttac
    12001 aaaaagacct aaaaaccaaa gacagtacta caccagacta tcaaataaaa gctgatcttt
    12061 tggcaagaac taccgaagtc atcaacaccc tcgaacaaca acacaccgaa tacttgagtc
    12121 gcctctatgt tgcttgggcg acaactccgc aaatgcgtaa tctagtcaag gtctcttctg
    12181 acatgcgtca aaaactaggc atgttacgcc gcaataccat tccaacgatg aaactatcta
    12241 ttgctcagtt aggcatgatg caacaatcgg ttaaatctgg aatgactgct gacgccattg
    12301 tcaatgctaa taatgctgcc cttcagatgc tagcagaaac aagtaaagaa gccatcccag
    12361 cattggaaca atcagcacaa agccctactt tgtctatgaa atctgtgaca agtctggcag
    12421 aaagtttagt agcacaaaat aatggcatca ttgcggcgat tgatcatgga cgcaaagaac
    12481 gagcacaact agaaagtgct attatcaggt ctgccgaaac cattaacgat tctgtcaaac
    12541 tacgtgacca aaatattgtg caagcacttc ttagtgaagg caaggaaact caaaaaacaa
    12601 ttgataaaac aactcacgca taagctaaac atcacctgtc acgctactta aaaagcaagc
    12661 catcagttag gttaatccct ttgatggctt gcttttttac tacttaacga ataatcgcct
    12721 tgtttgatat aacacttatc ttttatgatg ttattttcat aatacgaaca aggctagcac
    12781 gctcggcctc ttctaatttc aactcaatgt agtgaatcgt ctcttccagt tgcgggataa
    12841 tagaatactc taagccattg acgcgacgtc tagtcttttc aatgtcatca gccattagtt
    12901 gacaagtctt ttcaacttca gctaaccgta agagcttttc taatagttct tttgtctttt
    12961 ggatagtatt gtccatctca ctatttgagc tgaggtaact ataagcaaac tcaccttgtt
    13021 cttgctctct tgccgtatta gactggacat ggaatttagg cacattgaca ctcatgatat
    13081 tttcaatatc aatccataag gtcacttcat ggactggaac agcaaagagt tcttctacca
    13141 ttagactatt ttcagatgct tttgccaaga caaactcctt catattggca gcaagttctt
    13201 tttcgagagt ttgacgaagc tcattgtttt cacgaattaa atcaacgaag cggcgcatca
    13261 actcatcccg cttgtccttt aataatttat gacctcttgt agctgtcttc aatcgatttt
    13321 tcaagttact aagttccatg cgtgttggtt taacatttaa tcgtgccatt gatataactc
    13381 ctttcgtcaa gggcttgaaa ttgcatggtc aactcaatca tttgcaacaa aaacctttgt
    13441 catcgtggta tctgctttag gcaaataacg atctaacata tcatctttaa tgcgttttaa
    13501 ttcggtacgt ggcaaaatcg acaacaattc ccaacccaag tcaagacttt cttcaatgct
    13561 acggttggtg taaaatcctt ggttaatgta ttcttcttca aaccggttgg taaaggccac
    13621 atatagttta tccgtttcag aaagggctga ttcaccgagc acaacagcca attccttagc
    13681 ttgttttcct tgagcatagg ctgcaaagag ctgattcatt gtggcagcat ggtcttgtcg
    13741 agtcttacct tcacctgaac ctttatcttt taggcgagat agcgatggca agacattaat
    13801 aggcggtcta aaaccatttt tatatagttc ttgcgacaaa ataatctgac cttcggtaat
    13861 ataacctgtc aaatcgggga tagggtgggt aatgtcatct tctggcatgg ttaaaatagg
    13921 aatttgagtc actgaccctt ttttcccgat caagcgacca gcccgttcat ataaggtgga
    13981 gagattagta tagagatagc caggataacc tcgtctgcct ggaacttctc tgcgagcggc
    14041 tgatacttct cgtaaggctt cacaataatt tgtcatatct gtcatgatga ctaaaacatg
    14101 catacctttt tcataagcca agtattcggc tgttgtcaga gctatacgtg gtgttgcaat
    14161 gcgttcaata gcagggtcat tagctaaatt aataaataaa acagatcgat caatggcacc
    14221 cgtttcacgc aagtcattca taaagaattc tgcctcttca aaagtaatac ccatagctgc
    14281 aaacacaacc gcaaagttat catcagagtt tagaacagtt gcctgacgag caatctgtgc
    14341 ggccaattca ttatgaggta accctgagcc cgaaaaaact ggtaactttt gaccacgaac
    14401 gagggtattg aggtgatcaa tagctgagat acctgtctgg ataaattcgt ctgggtaatc
    14461 acgagcgaca ggattgatcg cttgaccatc gatatcaagg tatttttcgg gaataagttc
    14521 tggaccgccg tctatgggct gccccattcc atcaaagatg cgccctacca tatcttctga
    14581 tacggctaat tccaaaggat gccctgtaaa tcgaaccttg gttttggcta ggttgatgcc
    14641 agttgatcct tcaaatagct gtaccatagc cttgtcacct tggacttcta agacttgacc
    14701 tttacgcctt tctccattat gcaaagtaat atctaccaat tcgttgtagt gcactcctgc
    14761 aacttgatca acaatcatca aaggaccaac cacttcgcta accgtccgat attctttgag
    14821 aacgctcatc taaattcctc cctttgctaa aacgtggtga atctctttgg taaccttctg
    14881 agtaagccct ttaatctgct ctaagttttc ttctgggata aatttgctgc gtgcgatgcg
    14941 atcgcgtacc tgagcagtgc cttccataat ctcattaaaa taagctccca aagaaagggc
    15001 tttgctggct tcctcattaa aggtcaaaat attggttagc atggcttctt gtttcggaaa
    15061 ggaagtaaag gtatccaccg aatcaaaggc attttgctgg agataatcct cccgaatttg
    15121 ccgggcaaca gccatggtca aacgatcttg ttcagacagt gaatcaagcc ccaccaagcg
    15181 tacaatttct tctagactgg cttcacgctg caaaatagcc atggcacgag ttaccttgtt
    15241 ggaccaatta gattgctgtt tacggtcaat atagcttcct acatcatctt gatacaatga
    15301 ataagacgtc agccagttaa tcgctgggaa gtgacgccgt tgcgcaagag gcgcgtcgag
    15361 cccccagaaa actttgacaa tccgaagggt gttttgagtg acaggctctg aaatatcccc
    15421 tccaggagga gaaaccgcgc cgatggctgt aatggt
//
LOCUS       DAXMQE010000041        15347 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.041, whole genome shotgun sequence.
ACCESSION   DAXMQE010000041 DAXMQE010000000
VERSION     DAXMQE010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15347)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15347)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15347
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.041"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            complement(<1..411)
                     /locus_tag="ACF4ZO_001579"
     CDS             complement(<1..411)
                     /locus_tag="ACF4ZO_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HFD5487098.1"
                     /translation="MTATKQHKKVILVGDGAVGSSYAFALVTQNIAQELGIIDIFKEK
                     TQGDAEDLSHALAFTSPKKIYAADYSDCHDADLVVLTAGAPQKPGETRLDLVEKNLRI
                     NKEVVTQIVASGFKGIFLVAANPVDVLTYSTWKFS"
     gene            602..3088
                     /gene="gyrA"
                     /locus_tag="ACF4ZO_001580"
     CDS             602..3088
                     /gene="gyrA"
                     /locus_tag="ACF4ZO_001580"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006259 - DNA metabolic process [Evidence
                     IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HFD5487099.1"
                     /translation="MQDRNLIDVNLTSEMKTSFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRHMLVD
                     GHGNFGSMDGDGAAAQRYTEARMSKIALELLRDINKNTVNFQDNYDGSEREPVVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLAESIDAVKMVMEHPDCTTRELMEVIPGPDFPTG
                     ALVMGRSGIHRAYDTGKGSIVLRSRTEIETTQTGRERIVVTEFPYGVNKTKVHEHIVR
                     LAQEKRLEGITAVRDESSREGVRFVIEIRREASATVILNNLFKLTSLQTNFSFNMLAI
                     ENGVPKILSLRQIIDNYISHQKEVIIRRTRFDKDKAEARAHILEGLLIALDHLDEVIA
                     IIRNSETDVIAQTELMSRFDLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LSDILAKPERIITIIKEEMDEIKRKYANPRRTELMVGEVLSLEDEDLIEEEDVLITLS
                     NKGYIKRLAQDEFRAQKRGGRGVQGTGVNNDDFVRELVSTSTHDTLLFFTNFGRVYRL
                     KAYEIPEYGRTAKGLPIVNLLKLEDGETIQTIINARKEETAGKSFFFTTKQGIVKRTE
                     VSEFNNIRQNGLRALKLKEGDQLINVLLTSGQDDIIIGTHSGYSVRFNEASIRNMGRS
                     ATGVRGVKLREDDRVVGASRIRDNQEVLVITENGFGKRTSATDYPTKGRGGKGIKTAN
                     ITPKNGQLAGLVTVDGTEDIMVITNKGVIIRTNVANISQTGRATLGVKIMKLDADAKI
                     VTFTLVQPEDSSIAEINTDRENSISKNKDN"
     gene            3108..3857
                     /locus_tag="ACF4ZO_001581"
     CDS             3108..3857
                     /locus_tag="ACF4ZO_001581"
                     /EC_number="3.4.22.70"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004197 - cysteine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0016485 - protein processing [Evidence
                     IEA];
                     GO_process: GO:0045184 - establishment of protein
                     localization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sortase"
                     /protein_id="HFD5487100.1"
                     /translation="MVKKQKRRKIKSMSWARKLLIAVLLILGLALLFNKPIRNTLIAR
                     NSNKYQVTKVSKKQIKKNKEAKSTFDFQAVEPVSTESVLQAQMAAQQLPVIGGIAIPE
                     LGINLPIFKGLGNTELIYGAGTMKEEQVMGGENNYSLASHHIFGITGSSQMLFSPLER
                     AQNGMSIYLTDKEKIYEYIIKDVFTVAPERVDVIDDTAGLKEVTLVTCTDIEATERII
                     VKGELKTEYDFDKAPADVLKAFNHSYNQVST"
     gene            3940..4353
                     /locus_tag="ACF4ZO_001582"
     CDS             3940..4353
                     /locus_tag="ACF4ZO_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFD5487101.1"
                     /translation="MKLNAIHHVAIIVSDYNLSKNFYVNKLGFEIIRENYRPDRHDYK
                     LDLSCGRIELEIFGKVTSDPYYQAPPKRVSQPEFKSEACGLRHLAFRVTNIESYVDDL
                     KSLGIPVEPIRHDDYTGEKMTFFFDPDGLPLELHE"
     gene            4967..5401
                     /locus_tag="ACF4ZO_001583"
     CDS             4967..5401
                     /locus_tag="ACF4ZO_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5487102.1"
                     /translation="MTKKNHGVFWGLLLGSAAASITYLSLSSSKKDQLLKDSAKKIDD
                     LNAYLQDKSKQVLDAVSEKVQESKDAVEVYSGIAAETVEEKWQDTKDAVEVYGGIATE
                     TVEESLGQVKEKVEGIGEATSQTIQSKMEKLTSDKTDADDEK"
     gene            complement(5451..6362)
                     /locus_tag="ACF4ZO_001584"
     CDS             complement(5451..6362)
                     /locus_tag="ACF4ZO_001584"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HFD5487103.1"
                     /translation="MKTVRIFYNPNSGKKEDQLAGQVKDYFCQHGFSEDSVEIITPKD
                     ADQAFQLAKQAAKDKIDLVIPLGGDGTLNKIIGGIYEGGAHCLIGLVPSGTVNNFAKA
                     MHIPLQITEALDTILTGQIKQVDICKANQQYMISSLTLGLLADIAADVTAEEKRRFGP
                     LAFLKDSIRILKRNRSYAISLISHNHRIHLKTKFLLITMTNTIAGFPSFSPGAQADDG
                     YFQVYTMKKVSFFKFLWHINDFKQGDFSKAEEISHFQANTLSLLPQAKKQAILPRARI
                     DGDKSDYLPIQLDIIPKAISIIVPTED"
     gene            complement(6479..7129)
                     /locus_tag="ACF4ZO_001585"
     CDS             complement(6479..7129)
                     /locus_tag="ACF4ZO_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HFD5487104.1"
                     /translation="MNQTFKQSLPLSFSEEVANSVTHAIGAFAMLILLPISASYAYQT
                     YDLKAAIGISIFVISLFLMFLSSTIYHSMAYGSVHKYILRIIDHSMIYIAIAGSYTPV
                     ALSLVSGWLGYIIIVLQWGITLFGILYKIFAKRINEKFSLMLYIVMGWLVVFILPVII
                     QKTSLAFGLLMLFGGLSYTIGAVFYAKKRPYFHMIWHLFILLASALQFIAITFFML"
     gene            complement(7126..7566)
                     /locus_tag="ACF4ZO_001586"
     CDS             complement(7126..7566)
                     /locus_tag="ACF4ZO_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HFD5487105.1"
                     /translation="MIFPSLPYWKDLPDLDLYLDQVLLYVNQCTDFSEVSDNKSLTAS
                     MINNYVKHGYVTKPIKKKYQKQQLARLIAISLFKTVFPIQDISRVLEELQAQADSESL
                     YNTFVTCWNQKAPIEEDIPPIVQVACQTVKDYHKTIYLSQEVTQ"
     gene            7785..8633
                     /gene="ylqF"
                     /locus_tag="ACF4ZO_001587"
     CDS             7785..8633
                     /gene="ylqF"
                     /locus_tag="ACF4ZO_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HFD5487106.1"
                     /translation="MAMIQWFPGHMSKARRQVQENVKHVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLMILNKADLADATRTKEWKAYYESQGIKTLAINSKEQSTVKKVTEAAK
                     ELMADKIQRLRERGIQKETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKSNKELEILDTPGILWPKFADELVGLKLALTGAIKDQLLPMDEVTIFGLNYFKTHY
                     PSRLTKRFKNIPLEEEAPEIIMTLTRQLGFKDDYDRFYTLFVKEVRDGKLGQYTLDQV
                     GDMDVD"
     gene            8623..9414
                     /locus_tag="ACF4ZO_001588"
     CDS             8623..9414
                     /locus_tag="ACF4ZO_001588"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HFD5487107.1"
                     /translation="MSTSIKAIKESLEAVTSLLDPLFQELATDARLGVQKALKSRQKA
                     IQTDLAEEERLEAMLSYEKALYKKGYQAIAGIDEVGRGPLAGPVVAACVILPKYCKIK
                     GLNDSKKIPKAKHETIYQAVKEQALAIGIGIIDNQLIDEVNIYEATKLAMLEAIKQLE
                     GQLTQPDYLLIDAMTLDIAISQQSILKGDANSLSIAAASIVAKVTRDQMMANYDRIFP
                     GYGFAKNAGYGTKEHLQGLKAYGITPIHRKSFEPVKSMCCDSTNP"
     gene            9479..10315
                     /gene="dprA"
                     /locus_tag="ACF4ZO_001589"
     CDS             9479..10315
                     /gene="dprA"
                     /locus_tag="ACF4ZO_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009294 - DNA-mediated transformation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-processing protein DprA"
                     /protein_id="HFD5487108.1"
                     /translation="MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGC
                     KHPSHFIEAYKQLDIQKLKMEFKQFPSISILDKHYPMALKEIYNPPVLLFFQGNLDLL
                     EKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
                     AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPREEALSYHFPERNRIIAGLSRGIL
                     VVEAKNRSGSLITCQIGIEEGRDIFAVPGNILDGKSEGCLQLIKEGATCVTSGMYILS
                     EY"
     gene            10422..12551
                     /gene="topA"
                     /locus_tag="ACF4ZO_001590"
     CDS             10422..12551
                     /gene="topA"
                     /locus_tag="ACF4ZO_001590"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HFD5487109.1"
                     /translation="MGTKTTTKPKTGTKKSTTKKKSTAKKNLVIVESPAKAKTIEKYL
                     GRSYKVVASVGHIRDLKKSSMSIDFDNNYEPQYINIRGKGPLINSLKKEAKAAKKVYL
                     ASDPDREGEAISWHLSHILGLDPEDKNRVVFNEITKDAVKNAFVEPRQIDMNLVDSQQ
                     ARRVLDRIVGYSISPILWKKVKKGLSAGRVQSVALKLIIDRENEIKAFVPEEYWSIDG
                     LFKKGTKKFQASFYGLDGKKMKLSNNDDVKAVLAKLKGDDFLVSKVEKKERRRNAPLP
                     YTTSSLQQDAANKINFRTRKTMMVAQQLYEGIHLGENGTQGLITYMRTDSTRISPVAQ
                     NDAAQFISNRFGANYSKHGNRVKNTSGAQDAHEAIRPSSVNHTPEAIAKYLNKDQLKL
                     YTLIWNRFVASQMTAAVFDTVKVNLEQNGVLFVANGSQMKFDGYMAVYNDSDKNKMLP
                     EMEEGENVKKVSTSPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTLEVIQRRYY
                     VKLSAKRFEPTELGEIVNKLIVEFFPDIVDVAFTAEMEGKLDQVEIGEEEWQHVIDQF
                     YQPFVKELNKAESEIEKIQIKDEPAGFDCDVCGHPMVIKLGRFGKFYACSNFPECRNT
                     KAITKEIGVTCPICHKGQVIERKTKRNRIFYGCDRYPECDFTSWDLPVGRDCPKSGDY
                     LIEKKVRGGKQVMCSNETCDYKEEKIK"
     gene            12686..14032
                     /gene="trmFO"
                     /locus_tag="ACF4ZO_001591"
     CDS             12686..14032
                     /gene="trmFO"
                     /locus_tag="ACF4ZO_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HFD5487110.1"
                     /translation="MSQSTATYINVIGAGLAGSEAAYQIAKRGIPVKLYEMRGVKATP
                     QHKTTNFAELVCSNSFRGDSLTNAVGLLKEEMRRLDSIIMRNGEANRVPAGGAMAVDR
                     EGYAESVTAELENHPLIEVIRDEITEIPDDAITVIATGPLTSDALAEKIHALNGGDGF
                     YFYDAAAPIIDKSTIDMSKVYLKSRYDKGEAAYLNCPMTKEEFMAFHEALTTAEEAPL
                     NAFEKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQ
                     LRQDNAAGSLYNIVGFQTHLKWGEQKRVFQTIPGLENAEFVRYGVMHRNSYMDSPNLL
                     TETFQSRSNPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKREEALIFPQTTAIGS
                     LPHYVTHADSKHFQPMNVNFGIIKELEGPRIRDKKERYEAIASRALADLDTCLASL"
     gene            14209..>15347
                     /locus_tag="ACF4ZO_001592"
     CDS             14209..>15347
                     /locus_tag="ACF4ZO_001592"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015055948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase subunit B"
                     /protein_id="HFD5487111.1"
                     /translation="MQQQVAITETVLRDGHQSLMATRLSIEDMLPVLTILDKIGYYSL
                     ECWGGATFDACIRFLNEDPWERLRTLKKGLPNTRLQMLLRGQNLLGYRHYADDIVDKF
                     ISLSAQNGIDVFRIFDALNDPRNIQQALRAVKKTGKEAQLCIAYTTSPVHTLNYYLSL
                     VKELVEMGADSICIKDMAGILTPKAAKELVSGIKAMTNLPLIVHTHATSGISQMTYLA
                     AVEAGADRIDTALSPFSEGTSQPATESMYLALKEAGYDITLDETLLEQAANHLRQARQ
                     KYLADGILDPSLLFPDPRTLQYQVPGGMLSNMLSQLKQANAESKLEEVLAEVPRVRKD
                     LGYPPLVTPLSQMVGTQAAMNVILGKPYQMVSKEIKQYLAGDYGKT"
BASE COUNT         4966 a         2745 c         3168 g         4468 t
ORIGIN      
        1 tgagaatttc catgttgagt aagtcaaaac gtcaactggg ttagcagcaa caagaaagat
       61 tcctttgaaa ccagatgcaa cgatttgtgt aacaacctct ttattgatac gaaggttttt
      121 ttcaacaagg tcaaggcgtg tttcacctgg tttttgagga gcaccagctg ttaagacaac
      181 gagatcagca tcatgacagt ctgagtagtc agctgcatag atttttttag gtgatgtaaa
      241 agctagagcg tggcttaaat cttctgcatc tccttgagtt ttttctttaa aaatatcaat
      301 aataccaagt tcttgagcaa tattttgtgt taccaatgca aaagcgtatg atgaaccgac
      361 ggcaccatca ccgaccaaga ttactttttt gtgttgttta gttgcagtca tttctaaaca
      421 tctccttaat tttattagag caaaagctca tacggtctta ttttaacata ttgataattg
      481 tttgtcattg aattcagaaa aataatgaaa atagtttcct gataacgctt ccaataagaa
      541 aaaataagga atttatggta taatgaaatc tagtattgac tagaaaagga gcattcctta
      601 aatgcaagat cgaaatttaa ttgacgtcaa tctgacaagt gaaatgaaaa cgagtttcat
      661 tgactatgcc atgagtgtca ttgtggcaag agctttgcca gatgtgcgtg atggtctgaa
      721 acctgtgcat cgtcgtattc tctatgggat gaatgaactc ggtgtgacac ctgataaacc
      781 gcataaaaaa tctgctcgta ttacgggtga tgtcatgggt aaatatcacc cgcatgggga
      841 ttcttctatt tatgaagcta tggttcgtat ggctcagtgg tggagttatc gccatatgct
      901 tgttgatggg catggcaatt ttggttctat ggatggtgat ggtgctgccg ctcaacgtta
      961 tactgaagcg cgcatgagta aaattgcgct tgaattatta agggatatca ataaaaatac
     1021 cgttaatttt caagataact acgatggaag cgaaagagaa ccagtagtat taccagctcg
     1081 ctttcctaat ttattagtca atggagcgac agggattgcc gttgggatgg caactaacat
     1141 tccgcctcat aatttggcag agtctattga tgctgtcaag atggtaatgg aacatccaga
     1201 ctgtacaaca agagagttga tggaagtgat ccctggacct gactttccga ctggtgccct
     1261 tgttatgggg cgctcaggta ttcatagggc ttatgatact ggtaaaggtt ctatcgtttt
     1321 acgctctcga acagaaattg aaacaactca aacaggtcgg gaacgtattg tggttactga
     1381 atttccctat ggcgtcaata aaacgaaagt gcatgaacac attgttcgtt tagcacaaga
     1441 aaaaagacta gaaggtatta cagcagttcg tgacgaatct agccgtgaag gagtgcgttt
     1501 tgttatcgag attcgtcgag aggcatccgc gacagttatc ttaaataacc tctttaaatt
     1561 aacaagcctt cagacgaatt tcagttttaa tatgttggct attgaaaatg gtgtgcctaa
     1621 aatattgtca ctcagacaaa tcattgataa ttacattagt catcaaaaag aagttattat
     1681 acgtcgcacc cgatttgata aagataaagc tgaagccaga gctcatattt tagaaggctt
     1741 actgattgcc cttgatcatt tagacgaagt gattgctatt attcgtaaca gtgagacaga
     1801 tgtcattgct cagacagaat taatgtcacg tttcgacttg tctgaacgcc aaagccaagc
     1861 tattttggat atgcgtttgc gtcgtttgac tggtttggaa cgtgataaga ttcaatcaga
     1921 atatgatgat ttgttggcct tgattgctga cttatctgat attttagcca aaccagaacg
     1981 tattatcact atcatcaaag aagaaatgga tgagatcaag cgtaaatacg ctaacccacg
     2041 ccgtacagaa ttaatggtcg gtgaagtcct ttctctagaa gatgaagacc taattgaaga
     2101 agaagatgtt ttgattacct tgtcaaataa aggttatatc aagcgtcttg ctcaagatga
     2161 atttcgtgcc cagaagcgtg gtggacgtgg cgtccaagga actggggtca acaatgacga
     2221 ctttgtccgt gaattggtat caacaagtac ccatgatact ttgctcttct ttacgaattt
     2281 tgggcgtgtc tatcggttga aagcttacga aattccagaa tatggtcgta cagcaaaagg
     2341 tcttccaatt gttaatctat tgaaattaga agatggtgaa accattcaaa ctattatcaa
     2401 cgcacgtaag gaagaaacag caggtaaatc cttcttcttt acaacgaaac aaggcattgt
     2461 caaacgtaca gaagtttcag aatttaataa tatccgtcaa aacggtctcc gtgctcttaa
     2521 gttgaaagag ggagatcagc tgattaacgt ccttttgaca agcggtcagg atgacattat
     2581 cattggaact cattccggat attctgttcg ttttaatgaa gcaagcatcc gcaacatggg
     2641 ccgatcagct acgggtgttc gaggggttaa gcttcgtgaa gatgatcgcg ttgttggcgc
     2701 gtcacgtatt cgagataacc aagaagttct tgtaattacc gaaaatggct ttggtaagag
     2761 aacaagtgct acagactatc ctacaaaagg tagggggggg aaaggaataa aaacagctaa
     2821 tattacccct aaaaatggtc aattagctgg attggttacc gtagatggta cagaagatat
     2881 catggtgatt acaaataaag gtgtcattat tcgcacaaat gttgcaaata tttcgcaaac
     2941 aggtcgtgct actttgggtg ttaaaattat gaaactagat gctgatgcta agattgtaac
     3001 atttaccttg gttcagcctg aagacagtag tatcgctgaa atcaatactg atcgtgaaaa
     3061 tagtatttca aaaaataaag ataattaatc ataacaagga gtaaaaaatg gtaaaaaaac
     3121 aaaagcgtcg aaaaataaaa tccatgtcat gggcaagaaa actactaata gctgtacttt
     3181 taattctagg tttagcatta ctttttaaca aacctatccg aaatacatta attgctcgaa
     3241 actctaataa atatcaagta acgaaagttt cgaaaaaaca aatcaaaaag aataaagagg
     3301 ctaagtcaac atttgatttc caagccgtag agccagttag tacagagagt gtcttgcaag
     3361 cacaaatggc ggctcagcaa cttcctgtta tagggggcat tgccatacca gagcttggca
     3421 ttaatttacc aatttttaaa ggtttaggaa acactgagct tatttatggc gcaggaacga
     3481 tgaaagaaga acaagttatg ggaggagaaa ataattattc tcttgccagt catcatattt
     3541 ttggaattac aggttcatct caaatgctct tttcgccgct tgaaagagca caaaatggga
     3601 tgtccatcta tttaacagat aaagaaaaaa tttacgaata catcataaaa gatgttttca
     3661 cggtagctcc tgaacgcgtt gatgttatcg atgatacagc tggtctcaaa gaagtgactt
     3721 tagtgacttg tacagatatc gaagcaacag aacgtattat tgtcaaagga gaactaaaaa
     3781 cagaatacga ttttgataaa gcgcccgccg atgtattgaa agcttttaat cattcttata
     3841 accaagtatc tacctagata tatcttaaat ataatattta aaaagtagga ccatagagaa
     3901 aatttatctc atcctacttt ttttgaaagg agaaatatga tgaaactaaa tgccattcat
     3961 cacgttgcta ttattgtatc tgattataat ctgtcaaaaa atttttatgt gaataaactc
     4021 ggatttgaaa ttatcagaga aaattatcgt cctgacaggc atgattacaa attagattta
     4081 tcttgtggtc gtattgaatt ggagattttt ggtaaggtga caagtgaccc ctactatcaa
     4141 gctcctccta aacgtgtaag tcaaccagaa tttaaaagtg aggcctgtgg tttgaggcac
     4201 cttgcttttc gtgttaccaa cattgagagt tatgtagatg atctaaagag cttaggaatt
     4261 ccagtggagc ctatcaggca tgatgattac acaggtgaga aaatgacttt cttttttgat
     4321 ccggatggtt tgcctttaga attacatgaa tagacttatt aggttaacga ctggatcgtg
     4381 ctataaaact cgttaaaaat agttatttgt tgtatcttca tttgcttgat taatctcttt
     4441 tgatcgttaa atgatttggt taactttcaa agtgaagagc aatttttgga gtaatcttgt
     4501 cgaagttttt taatagaata actataggaa aagcaaaata tttgacgata aactcttaca
     4561 gtgttataat gacaatataa gttaataact gtgttgtcac tttgttgaaa tgttttcgta
     4621 ttaatgtttt tttatctatt gcgatagata attttacttc aatttttgat tgaaaatact
     4681 aaaataagtg atgtggtcac tttgacaacc atttattggt ccttttagat aagacaattt
     4741 tgtggctctt cagttgaaag gatgtgttgt tgatgttaga ggaaacaatc atgttaaatt
     4801 aactcaggct taaagaccaa aaaaggagtg aagtctatta tgaaaaaaag aaattttaaa
     4861 cttacagaaa tgttacaatt ggttttatta gtggttcctg ctgtaaaact tgctaaaaaa
     4921 atgtttaacg atagtaaaac accgtctaaa agaaagtagg tctacaatga ctaaaaaaaa
     4981 tcatggcgtt ttttgggggt tgttgcttgg atcagcagca gctagcatta cttacttaag
     5041 tttatcgtct tccaaaaaag atcaactctt gaaagatagt gctaaaaaaa tagatgatct
     5101 caacgcttac ttgcaagata aaagtaagca agttctggat gcagtatcgg aaaaagtaca
     5161 agaatccaaa gatgctgttg aagtttatag tggtattgcc gcagaaaccg ttgaagaaaa
     5221 gtggcaagat accaaagatg ctgttgaagt ttacggtggt attgccacag aaacagttga
     5281 agaatctttg ggacaggtta aagaaaaggt agaaggaatt ggcgaagcta ctagccaaac
     5341 tatccaatct aaaatggaaa aactcaccag cgataagaca gatgctgatg atgaaaaata
     5401 ggttttaaaa tacctttaag ataagacaaa aagtgccatt aggcactttt ttaatcttct
     5461 gttggaacaa taatcgaaat ggcttttgga atgatatcta attgaatggg cagatagtca
     5521 cttttatccc catcaatcct ggcacgtggt aatatcgctt gttttttagc ttgtggtagt
     5581 aagctaagcg tattggcttg aaaatgactg atttcctctg ctttggaaaa atcaccctgt
     5641 ttaaaatcat taatatgcca taaaaattta aagaaagaga cttttttcat ggtataaact
     5701 tggaaatagc catcgtcagc ttgagcacca ggagaaaaag aaggaaaacc agcaatggta
     5761 tttgtcatcg tgattaagag aaacttcgtt ttcaggtgaa tacgatggtt gtggctaatt
     5821 aaagagatgg catagctgcg atttcgtttc agtattcgaa tactatcttt taaaaatgct
     5881 agaggaccaa agcgtcgttt ttcctcagcc gttacgtcgg cagcaatatc agccagtaat
     5941 cctaaggtta aactggaaat catgtattgc tggttagctt tgcaaatatc aacttgcttg
     6001 atttgtcccg tcaagatagt atccaacgcc tcagtaattt gtaaagggat atgcatagcc
     6061 ttggcaaaat tattgactgt ccctgagggc actaagccta ttaaacaatg agctcctcct
     6121 tcatagatgc caccgatgat tttgtttagt gtcccatcgc caccaagagg gataaccaag
     6181 tcaatcttgt ccttagcagc ttgttttgct aattgaaaag cctggtcagc atctttaggg
     6241 gtaataatct ctacagaatc ttcggaaaaa ccatgttggc aaaaatagtc tttgacttgc
     6301 ccagcaagtt ggtcttcttt ctttccagaa ttaggattgt aaaaaatccg aacggttttc
     6361 atcaggtctc tcctttgaca gcttattact tgctatccat tataccactt ctaagaattg
     6421 atgtcttaca ccaactcatc acattaagcc tctcaatcag tctgagcatc tatttgtcct
     6481 aaagcataaa gaaagtgata gcgataaatt ggagggcaga ggccaataaa ataaagagat
     6541 gccaaatcat gtggaagtag ggtctttttt tggcataaaa taccgctcca atggtataag
     6601 acaagccacc aaataacatg agaagaccaa aagcaagact agttttttga atgatgactg
     6661 gcaagataaa cacaacgagc cagcccataa cgatataaag catcaaactg aatttttcat
     6721 tgatacgttt ggcaaaaatt ttgtataaaa tcccaaaaag cgtaatgccc cactgcaaaa
     6781 caataatgat atagcctagc caaccagaaa caagggataa agcaacaggt gtataacttc
     6841 ctgcgatagc aatgtaaatc atactgtgat caataatgcg tagaatgtat ttgtgaaccg
     6901 aaccataagc catggagtgg taaatcgtag aggacaaaaa catcaaaaag agactgatga
     6961 caaagatgga gataccaata gcggctttaa ggtcataagt ttgataagca tagctggctg
     7021 aaataggaag tagaatgagc atagcaaatg ctccgatagc gtgtgtcacg ctgtttgcta
     7081 cttcctcact aaaagataag ggtaaacttt gtttaaaggt ttggttcatt gggtcacctc
     7141 ctgtgataaa taaatagttt tgtggtaatc tttgaccgtt tgacaggcaa cctgcacaat
     7201 cggtggaatg tcctcctcaa tgggagcttt ctgattccaa caggttacaa aagtattgta
     7261 gagactttca gaatcagcct gtgcctgaag ttcctccaat acgcgactaa tatcttgaat
     7321 aggaaatacc gttttaaaca aactgatggc aattaagcgc gctagttgtt gcttttggta
     7381 ttttttcttg ataggtttag tcacataccc atgcttgacg taattattaa tcatagatgc
     7441 cgttagtgat ttattatctg acacttctga aaaatcagtg cactggttga cataaagtaa
     7501 cacttgatcc aaatataagt ctaaatcagg gaggtccttc caataaggta atgatggaaa
     7561 aatcataggt tcgtctctct atctagtttt gataactaga ttatatgatt aatgaaaact
     7621 tattgcaagc aaaaactgta aagacttaaa agaggaaagt agaaatggcg aagtgaagct
     7681 aatcatgcta taatgttaaa gaattgattg ggatagatgc cttctgtcgc aatcagacta
     7741 ttttatcacg aagaagatga tgctacgaaa ggaatgatac actcatggca atgattcaat
     7801 ggtttcctgg gcacatgtcc aaagccagaa gacaggttca ggaaaatgta aagcatgttg
     7861 actttgtaac tattttagtg gatgcacgct taccactttc tagtcaaaat cccatgctta
     7921 caaaaattgt tggtgataaa cctaaattaa tgattttaaa taaagctgac ttggcagatg
     7981 caactcgaac taaagagtgg aaagcctact atgaaagtca aggcattaaa acactagcca
     8041 tcaattctaa agaacaatca acagttaaaa aagtaacaga agcagccaag gaactcatgg
     8101 ctgataaaat tcaacgcttg cgagagcgcg gcattcaaaa agaaaccttg cgaaccatga
     8161 tcattggcat tccaaatgct ggtaaatcta ccttgatgaa tcgcttggct ggtaagaaaa
     8221 ttgctgtagt tggcaataaa cctggtgtga ctaaaggaca acaatggttg aagtccaata
     8281 aggaattgga aattctagat acccctggta ttttatggcc aaaatttgcg gacgaattgg
     8341 ttggcttaaa attagcttta acaggtgcta tcaaggacca attactacca atggatgagg
     8401 tcactatttt tggtttgaat tactttaaaa cacattatcc tagtcgcctt actaagcgtt
     8461 ttaagaatat tcctcttgag gaagaagctc ctgaaatcat tatgaccttg acacgccaac
     8521 tgggatttaa agatgattac gaccgcttct acactttatt cgtcaaggaa gttcgtgatg
     8581 gtaaattagg tcaatacacc ttagatcagg tgggagatat ggatgtcgac tagtattaaa
     8641 gccatcaaag aaagcctgga agctgttact agcctcttgg accccctctt tcaagaattg
     8701 gcaactgacg ctaggttagg cgtccaaaaa gcgctaaaaa gtcgacaaaa ggctattcag
     8761 accgatttag cagaggaaga acgattagaa gccatgcttt cttatgaaaa agcgctttat
     8821 aaaaaaggtt atcaagccat tgcaggtatt gacgaggtgg gacgtggtcc cttagcaggt
     8881 cccgttgtgg cagcttgtgt gattttacct aagtattgta aaattaaagg ccttaatgat
     8941 tctaaaaaaa tccctaaagc taagcatgag accatttatc aggcagtgaa agaacaggct
     9001 ttggctatcg gtatcggtat tattgacaat cagctgattg atgaggtcaa tatttatgaa
     9061 gcaaccaaac tagctatgct agaagccatt aaacagttgg agggccaact cacacaacca
     9121 gattatctct tgattgatgc catgacattg gatattgcta tttcgcagca gtctattctt
     9181 aaaggcgatg ccaattcctt gtctattgca gcagcatcaa ttgtagctaa ggtcaccaga
     9241 gatcagatga tggctaacta tgatcgcatt tttcctggtt atggctttgc taaaaatgca
     9301 ggctatggca ccaaagaaca tttacaggga ttaaaagctt acggcataac gcctatccat
     9361 cgtaaaagtt ttgaacctgt taaatccatg tgctgcgatt caactaatcc ttaaaaagtt
     9421 ctgtttttag cagaattttt ttctttttta cgaataaatg aagtaaggag gtaacttagt
     9481 gaatcatttt gaactttata agctaaagaa agctggactg actaataaaa acattctcaa
     9541 tattcttgac taccaagaac accaggaaaa atcgttgtca cttcgagata tggccgttgt
     9601 ttctggttgt aagcatccgt ctcactttat agaagcctat aagcagttag atattcaaaa
     9661 attaaaaatg gaatttaaac aatttcctag tatttctatc ttagataagc attacccaat
     9721 ggcattgaaa gaaatataca atccacctgt cctcttgttt tttcagggaa atttagacct
     9781 tcttgagaaa cctaaattag ctattgttgg ctccagacgc tcaagcgata ccggagtaaa
     9841 gtctgtccgt aaaattctta aagaactcgg gaaccgtttt gtgattgtta gcggacttgc
     9901 tcgaggtatc gacactagtg ctcatttagc ctgccttaaa aatgggggac aaaccatcgc
     9961 tattattgga acagggttgg atcgctttta ccctaaagaa aatagggagt tgcaaacttt
    10021 cttagggaaa aatcatcttg tgctaacaga atacggtcca agagaagaag ctttatctta
    10081 tcactttcca gaacggaatc gtattatcgc aggccttagc cgaggtattc ttgtcgttga
    10141 agcaaaaaat cgttcaggtt ccttgattac ttgtcaaatt gggatagaag aaggccgaga
    10201 catttttgct gtcccaggaa acattttgga cgggaaatcc gaaggttgcc ttcagttaat
    10261 taaagaggga gcaacatgcg tcacatcggg catgtatatc ctttcagagt actaaaaaag
    10321 ttaaagtttc ttcctatata gcattttttt attgacagtt tcttaaaaat gggatattat
    10381 gctataagct ttaaacaaac tgttatagga agtgtgtcga attgggaaca aaaactacaa
    10441 ctaagccaaa aacgggtact aaaaagtcca ccactaaaaa gaaatcaaca gcgaaaaaaa
    10501 atctcgttat tgttgaatca cctgccaaag ctaagactat tgaaaaatat cttggacgca
    10561 gttataaagt tgttgcttcg gtaggacata ttcgtgactt aaaaaaatcg tctatgtcta
    10621 ttgattttga taataattat gagccacaat acattaatat ccgtggtaag ggacccctta
    10681 tcaattcttt aaaaaaagaa gccaaagctg ctaaaaaagt ttacttggca agtgacccgg
    10741 accgtgaggg agaggctatt tcttggcatt tgtcacatat tctaggactc gatcctgaag
    10801 ataaaaaccg agtggttttc aatgaaatta ccaaagatgc ggtgaaaaat gcttttgtgg
    10861 aacctcgtca aattgacatg aacttagtgg attctcaaca agcccgtcgc gtcttggacc
    10921 gtattgtagg ttactccatc tcacctattc tttggaaaaa ggtcaaaaaa ggcctttcag
    10981 caggacgtgt ccagtcggtt gctttaaaac tcatcattga ccgtgaaaat gaaatcaaag
    11041 cctttgttcc agaagaatac tggtctattg atggcctctt caaaaaagga accaagaagt
    11101 ttcaagcaag tttttacggt cttgatggca agaagatgaa actttccaac aatgatgacg
    11161 ttaaagcagt tcttgctaaa ttaaaaggtg atgatttctt ggttagtaag gttgagaaaa
    11221 aagagcgccg tcgaaatgcc ccattacctt atacgacctc ttctctacaa caagatgctg
    11281 ctaataaaat caatttcaga acgcgtaaaa ccatgatggt agcccaacaa ctgtatgagg
    11341 ggattcattt aggagaaaac ggaactcaag gtttaattac ctatatgcgt actgattcta
    11401 cacggattag tcctgtagcg caaaatgatg ctgcccaatt tatcagtaat cgttttggag
    11461 ctaattattc taaacatggg aatcgtgtca aaaataccag tggtgcccaa gatgctcacg
    11521 aggctattcg tccatctagc gtcaatcata caccagaagc tattgccaaa taccttaaca
    11581 aggatcagtt aaaactttat actctgattt ggaatcgttt tgtggctagc caaatgacag
    11641 cagctgtttt tgataccgta aaggtgaatt tggagcaaaa tggcgtgctt tttgttgcca
    11701 atggaagcca aatgaaattt gacggttata tggctgttta taatgactca gataaaaaca
    11761 aaatgttacc tgaaatggaa gaaggagaaa acgttaaaaa ggtatcaact tctccagaac
    11821 agcacttcac gcaacctccg gctcgctact ccgaagcaac tctgattaaa actttagaag
    11881 aaaatggggt cggtcgacca tcaacttatg ccccaacctt agaagtgatt caacgcaggt
    11941 actatgttaa attatctgct aagcgctttg agccaactga gcttggggaa attgtcaaca
    12001 agcttattgt cgaatttttc ccagatattg ttgatgttgc ctttactgcc gagatggaag
    12061 gtaagctaga tcaagttgaa atcggtgaag aagaatggca acatgtcatc gatcaattct
    12121 atcaaccctt tgtcaaagaa ttgaataagg ctgagtctga aattgaaaag attcaaatca
    12181 aagatgagcc agctggtttt gactgtgatg tttgtggcca cccaatggtc attaagttag
    12241 gacgttttgg gaaattttac gcgtgcagca acttccctga gtgtcgtaat acaaaagcca
    12301 tcactaaaga aatcggtgtt acctgtccca tttgtcataa gggacaagtc attgaacgaa
    12361 aaactaagcg caatcggatc ttttatggtt gtgatcgcta cccagaatgt gacttcactt
    12421 cttgggattt accagttgga cgtgactgtc ctaagtctgg tgactatctt attgagaaaa
    12481 aagttcgtgg tggcaaacaa gtaatgtgta gcaatgagac ctgtgattac aaggaagaaa
    12541 aaattaaatg aggattacaa aagaggctac acatagcctc ttttgctttt ttcccctttc
    12601 tgttataata agtcaggtaa ctacattaga aagatttgtg ggtctgccat ctaagagatg
    12661 tcattcccga agaggtatta gtgacttgtc tcaatcaact gcaacttata ttaatgttat
    12721 tggagctgga ctagctggtt ctgaagctgc ctatcagatt gctaagcgcg gtatccccgt
    12781 taaattgtat gaaatgcgtg gtgtcaaagc aacaccgcaa cataaaacca ctaattttgc
    12841 cgaattggtc tgttccaact catttcgtgg tgatagctta accaatgcag tcggtcttct
    12901 caaagaagaa atgcggcgat tagactccat tatcatgcgt aatggtgaag ctaatcgtgt
    12961 acctgctggg ggagcaatgg ctgttgaccg tgaggggtat gcagagagtg tcactgcaga
    13021 gttggaaaat catcctctca ttgaggtcat tcgtgatgaa atcacagaaa tccctgacga
    13081 tgccattacg gttatcgcga cgggtccatt gacttcagat gccttggcag aaaaaattca
    13141 cgcgctaaat ggtggcgacg gattctattt ttacgatgca gcagcgccta tcattgataa
    13201 atctactatt gatatgagca aggtttacct caaatctcgc tacgataaag gcgaagctgc
    13261 ttacctcaac tgccctatga ccaaggaaga attcatggct ttccatgaag ctctgacaac
    13321 cgcagaagaa gcaccgctga atgcctttga aaaagaaaag tattttgaag gctgtatgcc
    13381 gattgaagtt atggctaaac gtggcattaa aaccatgctt tatggaccta tgaaacccgt
    13441 tggattggaa tatccagatg actatacagg tcctcgcgat ggagaattta aaacgccata
    13501 tgccgtcgtg caattgcgtc aagataatgc agctggaagc ctttataata tcgttggttt
    13561 ccaaacccat ctcaaatggg gtgagcaaaa acgcgttttc caaacgattc cagggcttga
    13621 aaatgctgag tttgtccgct acggcgtcat gcatcgcaat tcctatatgg attcaccaaa
    13681 tcttttaacg gaaaccttcc aatctcggag caatccaaac cttttctttg caggtcagat
    13741 gactggagtt gaaggttatg tcgaatcagc tgcttcaggt ttagtagcag gaatcaatgc
    13801 tgctcgtttg ttcaaaagag aagaagcact tatttttcct cagacaacag ctattgggag
    13861 tttgcctcat tatgtgactc atgccgacag taagcatttc caaccaatga acgtcaactt
    13921 tggcatcatc aaagagttag aaggcccacg cattcgtgac aaaaaagaac gttatgaagc
    13981 tattgctagt cgtgctttgg cagatttaga cacctgttta gcgtcgcttt aacactaaaa
    14041 aagagttcct tttcagttga gttgctgaag aggacttttt tatttgctga tttgagcgct
    14101 agctatgtaa aagaatgcac aaaaaataca tgaatagact atggtcacta gaagcaatat
    14161 tatataatga atagtactca ttagttgatt cagtttggag gttttagcat gcagcagcaa
    14221 gtcgcaataa cagaaacagt tttacgggac ggtcatcaaa gtttgatggc aacgcgttta
    14281 tctattgaag atatgcttcc tgtccttacc atcttagaca agattggtta ttattcccta
    14341 gagtgttggg gaggagcaac ctttgatgcc tgtattcgtt ttttgaacga agacccttgg
    14401 gaaaggctgc gcacgttaaa aaaaggctta cctaataccc gtttacaaat gttattaaga
    14461 ggccaaaacc ttttaggcta ccgtcattat gcagatgaca tcgttgacaa attcattagt
    14521 ttatcagctc aaaatgggat tgatgttttc cgcatttttg atgccctaaa tgacccacga
    14581 aatatccagc aagctttaag agctgtgaaa aagacgggta aagaggctca actgtgtatt
    14641 gcctatacaa ctagcccagt gcacacgctt aactattacc tttctttagt gaaagaattg
    14701 gttgagatgg gagctgattc tatctgcatc aaagatatgg ctggtattct aactcccaaa
    14761 gcggctaaag agttggtatc tggtatcaaa gccatgacta acttacctct tattgtgcat
    14821 acccatgcaa ctagtggcat ttctcagatg acctatctag cagcagtaga agctggtgct
    14881 gatagaattg atacggcttt gtcacctttt agcgaaggca cttcacaacc tgctacagaa
    14941 tccatgtatt tagccttaaa agaagcaggt tatgatatca cattagatga aacgctactg
    15001 gaacaggctg ctaatcacct tcgacaagcc cgtcaaaagt acttagcaga tggcattctg
    15061 gatcccagtc ttctctttcc agacccaagg acactacaat accaagttcc tggaggcatg
    15121 ttatctaata tgctatctca gctgaaacaa gccaatgccg aatcaaaatt agaagaagtt
    15181 ttagcagaag ttcctcgggt aagaaaagac ttgggttatc ctcccttagt aacaccgctt
    15241 agccaaatgg tcgggactca agctgctatg aatgtgattt taggaaaacc ttaccagatg
    15301 gtgtctaagg aaattaaaca atacttggca ggcgactatg gcaaaac
//
LOCUS       DAXMQE010000042        14551 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.042, whole genome shotgun sequence.
ACCESSION   DAXMQE010000042 DAXMQE010000000
VERSION     DAXMQE010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14551)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14551)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14551
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.042"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            complement(<1..544)
                     /locus_tag="ACF4ZO_001593"
     CDS             complement(<1..544)
                     /locus_tag="ACF4ZO_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase family protein"
                     /protein_id="HFD5487112.1"
                     /translation="MTAQTPIHVYSEIGKLKKVLLHRPGKEIENLMPDYLERLLFDDI
                     PFLEDAQKEHDAFAQALRDEGIEVLYLETLAAESLVTPEIREAFIDEYLSEANIRGRA
                     TKKAIRELLMAIEDNQELIEKTMAGVQKSELPEIPASEKGLTDLVESNYPFAIDPMPN
                     LYFTRDPFATIGTGVSLNHMF"
     gene            complement(819..1499)
                     /locus_tag="ACF4ZO_001594"
     CDS             complement(819..1499)
                     /locus_tag="ACF4ZO_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HFD5487113.1"
                     /translation="MIRREDYQYLRKLNDFRYFSIEQFDKIVGQMEFRKAKKDHILFF
                     EGDKRDKLFLVTSGYFKVEQSDQSGTFMYTDFIRHGTIFPYGGLFTDDYYHFSVVAMT
                     DVTYFYFPVDLFEDYSLENRLQMKHLYSKMSKLLELHELRVRNLITSSASSRVIQSLA
                     ILLVEMGKDSDTLPFQLTTTDIAQISGTTRETVSHVLRDLKKQELITIKGKYLTYLDK
                     DYFLQYTK"
     gene            1641..2114
                     /locus_tag="ACF4ZO_001595"
     CDS             1641..2114
                     /locus_tag="ACF4ZO_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HFD5487114.1"
                     /translation="MNKKETRHQLIRSLISETTIHTQQELQERLQKNGITITQATLSR
                     DMKELNLVKVTSGNDTHYEALAISQTRWEHRLRFYMEDALVMLKIVQHQIILKTLPGL
                     AQSFGSILDAMQIPEIVATVCGDDTCLIVCEDNEQAKACYETLSHYTPPFFFSNK"
     gene            complement(2280..2996)
                     /locus_tag="ACF4ZO_001596"
     CDS             complement(2280..2996)
                     /locus_tag="ACF4ZO_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="B3/4 domain-containing protein"
                     /protein_id="HFD5487115.1"
                     /translation="MVEFVADQSFWELFPDAKLGVVLLKDVQNQAESPEDVKQLLADS
                     HELAKAYLTADNFSDNQVVQVYRKAYQHFKTKKGARSSIEALLKRVSNGQSIPSINPL
                     VDIYNAASLRFGLPVGAEDSDSFIGDLRLTTTDGGDDFYLIGDADNNPTLPNELCYKD
                     DIGAVCRCLNWRDGERTMVTEHTKNAFLIIEALDQEGQNRLQEALDFIEGSAKMYLHA
                     ITSVHVLDKDNPHVPLFTEN"
     gene            complement(3019..4098)
                     /locus_tag="ACF4ZO_001597"
     CDS             complement(3019..4098)
                     /locus_tag="ACF4ZO_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HFD5487116.1"
                     /translation="MNLATDYFSRQTPIVEKLVAYGFEKRDNGYFYNERFMEGEFEAQ
                     LRIDEAGNIWDRVIDCDLEEDYLPLQQAAWQGTYTGQVRAAYLELLERLSVACFEVTP
                     FQSMQANRLAKHITKEWSDPMDYPFEKHPDLATYRVEGKWYAVIFSLLADKLDQIPER
                     LVGQTCEVMTVKVNPKDLPQLLQQEGIYPAYHMSKKNWISIILDDKVTDDKLWTLVTQ
                     SRQLVNPNGLSNPNGPDYWVIPANLKYYDIDAEFAANDVILWTQKAGIAVGDYVLIYM
                     TAPVKSIRYACQVLETDIPNEGYRKNPNIDKLMRLRKCQQYKDGLLSFDLMKKHGVAA
                     VRGPRRLSPQLIAFLKEKEYLKENN"
     gene            complement(4171..5904)
                     /locus_tag="ACF4ZO_001598"
     CDS             complement(4171..5904)
                     /locus_tag="ACF4ZO_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HFD5487117.1"
                     /translation="MKRYPLLVQLISYVFVIVIALITTLGLLYYQTSSRNIRQLIERD
                     TRQSIRQSSQFIDAYIKPLKETTSVLAKNSEIQDFASQIHQENDKQVLQLMKMILATN
                     SDLQAAVLVTKDGRTVSTNPQLTMKTSSDMMAETWYKAAIDRQAMPILTPARQLSLSS
                     KKEWVVSVTQEVVDAAGHNLGVLRLDIAYPTVKASLDQLQLGRQGFAFIVNDKHEFVY
                     HPKKSVYSSSKEMAAMKPYLAIQNGYTKDKTSFVYQKLIPNSQWTLVGVASLDQLHRV
                     QRQIFWSFLGMGLLACLICGLATILVLRKWIRPIQQLQQVILAIQKGDRQLRAQETGS
                     PELTDLAQQFNALLDQIDSLMVAVADKEKAIGQYRLQALASQINPHFLYNTLDTIIWM
                     AEFNDSKRVVEVTKSLAKYFRLALNQGNEYIRLADELDHVSQYLFIQKQRYGDKLSYE
                     VQGLDVYADFVIPKLILQPLVENAIYHGIKEVDRKGMIKVTVSDTAQHLMLTVWDNGK
                     GIEDSSLTNSQSLLARGGVGLKNVDQRLKLHYGEGYHMTIHSQSDHFTEIQLSLPKMH
                     ELMADDTQENE"
     gene            complement(5901..6641)
                     /locus_tag="ACF4ZO_001599"
     CDS             complement(5901..6641)
                     /locus_tag="ACF4ZO_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFD5487118.1"
                     /translation="MYSLLIVEDEYLIRQGIRSLVDFSQFKIDRVNEAENGQLAWDLF
                     QKEPYDIVLTDINMPKLNGIQLAELIKQESPQTHLVFLTGYDDFNYALSALKLGADDY
                     LLKPFSKADVEDMLGKLQQKLDLSKKTETIQELVEQPQKEVSAIAMAIHERLADSDLT
                     LKSLAQQLGFSPNYLSVLIKKELGMPFQDYLVQERLKKAKLLLLTSNLKIYEIAEQVG
                     FEDMNYFSQRFKQLVGVTPSQYKKGGQA"
     gene            complement(6729..7835)
                     /gene="msrB"
                     /locus_tag="ACF4ZO_001600"
     CDS             complement(6729..7835)
                     /gene="msrB"
                     /locus_tag="ACF4ZO_001600"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033743 - peptide-methionine (R)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HFD5487119.1"
                     /translation="MEHKWKLWLFIVGVVLLIGGASVLIQKGQAKAFSQGKPQIPAKK
                     VKSTKVDPNAPVDQKVIYLAGGCFWGVEEYFSQVDGVLDAVSGYANGRGDTTNYQLIH
                     QTGHAETVEVAYDANRISLKELLLHFFRIIDPTSLNKQGNDRGSQYRTGIYYTDKADL
                     AIIDEVFKEKAKDYKKKIVVEKAPLKHFIKAEDYHQDYLKKNPNGYCHIDINQATYPV
                     IDESKYPKPSATEIKEKLSADEYRVTQKNETEKAFSNRYWDSFDAGIYVDVVTGEPLF
                     SSKDKFESGCGWPSFSRPISPDVVRYKEDKSFNMTRTEVRSRSGNSHLGHVFTDGPKD
                     QGGLRYCINSLSITFIPKADMEAKGYGYLLSSVE"
     gene            complement(7878..8501)
                     /locus_tag="ACF4ZO_001601"
     CDS             complement(7878..8501)
                     /locus_tag="ACF4ZO_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA disulfide reductase family protein"
                     /protein_id="HFD5487120.1"
                     /translation="MKKGLLVTTGLACLGLLTACSTQDNMAKKEITQDKMSMAAKKKD
                     KMSTSKDKSMMADKSSDKKMTNDGPMAPDFELKGIDGKTYRLSEFKGKKVYLKFWASW
                     CSICLSTLADTEDLAKMSDKDYVVLTVVSPGHQGEKSEADFTKWFQGTDYKDLPVLLD
                     PDGKLLEAYGVRSYPTEVFIGSDGVLAKKHIGYAKKSDIKKTLKGIH"
     gene            complement(8514..9224)
                     /gene="ccdA2"
                     /locus_tag="ACF4ZO_001602"
     CDS             complement(8514..9224)
                     /gene="ccdA2"
                     /locus_tag="ACF4ZO_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HFD5487121.1"
                     /translation="MTLSLVLMVSVFGAGLLSFFSPCIFPVLPVYLGILLDADDSKTI
                     TIFGKKLYWYGIVKTLAFIFGLSTIFVILGYGAGFLGNILYAVWFRSFLGALVIILGI
                     HQMGLITIKSLQFQKSLTFHNNKNRNGLFNAFILGLTFSFGWTPCVGPVLSSVLALVA
                     SGGNGAWQGGVLMIIYTLGLGIPFLLISFASGIVLKQFNKLKPHILLLKKVGGVLIIV
                     MGILLMTGTLNNLAQLFG"
     gene            complement(9445..10377)
                     /locus_tag="ACF4ZO_001603"
     CDS             complement(9445..10377)
                     /locus_tag="ACF4ZO_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HFD5487122.1"
                     /translation="MPTLPKASSAITLINLDQLTEHDQEALVSEGLIDAEVFDYAKDK
                     NETSFMEENKEKLTIVFQILDRQEEAYHPNYIPRVIPITLFLNDQSLYILGHDHSLTL
                     IEEVFPDLDESRSPRHLVFQLLTAFTKQYVPLMDEIAQQRDKLIEALRQKANKTNLES
                     LANLQSGTVYILMGSKQNEQMLAELKDMPGQQDLEEDEAEQLRDAIIEARQLSNMCDL
                     NTRVLKEISSSYNNVLSNNLNNNVTSLTIFSIGISIIAMVTSFYGMNVKLPFAKVDSV
                     WFWIVLTTSLVALLIMVVMYWYVHKRNRNASKRI"
     gene            complement(10469..11428)
                     /locus_tag="ACF4ZO_001604"
     CDS             complement(10469..11428)
                     /locus_tag="ACF4ZO_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015631803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFD5487123.1"
                     /translation="MAKVRYGIVSTAQVAPRFIEGVRLAGNGEVVAVSSRSLDKAKAF
                     AAAHQLPKAYGSLDDMLLDASIDAIYVASINQDHFPAAKKALLAGKHVLVEKPFTLTA
                     AQAEELFALAQERGLFLMEAQKAVFIPMTKRLKSLIAAGELGDIVSASSTTAYPNIDH
                     VIWFRDLEKGGGTVHFMAPYALSYLPYLFDTDIVSASGVAHFPEGQSDSQSKLVLTLS
                     NGVLVDIFLTTHLSLPHELVIYGTKGRLEIPHFWKTTHATLVRPDGSRSVIEATMSSD
                     FEAEAYHVSQMILEGQLTSPVMTKSLTLSGVGLIEKLYRSWGK"
     gene            12438..13170
                     /locus_tag="ACF4ZO_001605"
                     /pseudo
     CDS             12438..13170
                     /locus_tag="ACF4ZO_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000934864.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(13386..>14551)
                     /locus_tag="ACF4ZO_001606"
     CDS             complement(13386..>14551)
                     /locus_tag="ACF4ZO_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="class I tRNA ligase family protein"
                     /protein_id="HFD5487124.1"
                     /translation="EFTERQPFQNVLIHGLIRDEEGRKMSKSLGNGIDPMDVIEKYGA
                     DSLRWFLSNGSAPGQDVRFSYEKMDASWNFINKIWNISRYILMNNEGLTLEEAESNVA
                     KVAASEAGNVTDQWILHNLNETIAKVTENFDKFEFGVAGHILYNFIWEEFANWYVELT
                     KEVLYSDNEAEKVITRSVLLYTLDKILRLLHPIMPFVTEEIYAQYAQGSIVTAAYPTV
                     TPAFENEAAHKGVESLKDFIRAVRNARAEVNVAPSKPITILVKTADSELEDFFNSNIN
                     YIKRFTNPEKLEISSAIAAPELAMTSIITGAEIYLPLADLLNVEEELARLDKELAKWQ
                     KELDMVGKKLGNERFVANAKPEVVQKEKDKQADYQAKYDATQERIVEMHKLVK"
BASE COUNT         4309 a         3071 c         2694 g         4477 t
ORIGIN      
        1 agaacatgtg gttaagagaa acacctgtac cgatagttgc gaatgggtcc cgtgtgaaat
       61 aaaggtttgg cattgggtcg atggcaaatg ggtaattgga ttcaaccaag tcagtcaagc
      121 ctttttcaga tgctgggatc tctggaagtt cagatttttg aactcctgcc atggtttttt
      181 caatcaattc ttgattgtct tcgatagcca tcaacaattc acgaatggct tttttagtag
      241 ctcttccacg gatattagct tcacttaggt attcatcgat gaaagcttcg cgaatttctg
      301 gagtgacaag agattctgca gctaaggtct caaggtacaa gacttcaata ccttcgtcac
      361 gcaaagcttg ggcaaaagca tcatgttctt tttgggcatc ctctaagaat ggaatgtcat
      421 caaacaacaa gcgttccaag tagtctggca taagattttc aatttcttta ccgggtctgt
      481 ggagcaacac tttttttaat tttccaattt cagaataaac atgaattggt gtttgagcag
      541 tcataagaat tacctctttc taattggttt ttgtgaattc accgtcaaga ttcttaactc
      601 ttgcttatat tcctagtgta ctccttaaaa aagataaaaa taaggtattt ctcacagcca
      661 ttttgagtaa tcgcttacat tttttgagcg ttgtttttat ttttatagat ttgtattcgt
      721 ttacttgtat gtttttttac atcttagtgt aaaaatttat acttataaat taaaataagt
      781 cagaaaaact tttaaaataa agtgttctga cctttaattc actttgtgta ttgtaaaaaa
      841 tagtctttat ctagataagt caaatactta ccttttatgg taatcaattc ttgcttcttc
      901 aaatccctaa gcacatggct aactgtttct cttgtcgtcc cacttatttg agcaatatct
      961 gttgttgtta attgaaaagg taaggtatca ctgtctttac ccatttcaac cagcaaaatc
     1021 gccagagatt gaatcacacg agaactagca cttgatgtaa tcaagtttcg gaccctcaac
     1081 tcatgtaact cgagcagttt agacatctta ctatataagt gtttcatttg tagacgattt
     1141 tcaagcgagt aatcttcaaa taaatcgact ggaaagtaaa aataagtcac gtctgtcatg
     1201 gctaccactg aaaaatggta ataatcatct gtaaaaaggc caccgtaagg aaaaatggtg
     1261 ccgtgtctga tgaaatccgt atacatgaag gttcctgatt gatcggactg ctccaccttg
     1321 aaataaccag aggtcactag aaaaagctta tctcttttat ctccctcaaa aaaaaggata
     1381 tggtcctttt tagcttttcg gaattccatc tgccctacaa ttttgtcaaa ttgttcaata
     1441 gaaaagtagc gaaaatcgtt tagttttcta aggtattgat aatcttctct tcgaatcaca
     1501 caaatctcct ttttctaaac atcatcttta ttttaccata aaaaagccat tttgtaagcg
     1561 gttcatcaaa aactttacac cttctcctct ttttgctata ctcggattgt tatcaattac
     1621 gttaaaggaa gattataaca atgaataaga aagagacgcg tcaccaactc atacgttccc
     1681 tcatctctga gacaactata catacacagc aagaattaca agaacggttg caaaaaaatg
     1741 gcatcacgat cactcaggct accctatcac gtgacatgaa ggaattgaac ctggtcaaag
     1801 taacttctgg aaacgacaca cactatgaag cgttagccat ttcacaaacc cgctgggaac
     1861 atcgtcttcg tttttacatg gaagacgctt tggtcatgtt aaagatagtt caacatcaaa
     1921 ttattttaaa aacgttacct ggactagccc aatcctttgg ctccatttta gatgccatgc
     1981 aaattccaga aattgtagca acggtctgtg gtgatgatac ttgcttgatt gtctgtgaag
     2041 acaatgagca agccaaggct tgttacgaaa cccttagtca ttacacgcca cctttcttct
     2101 ttagtaacaa ataaggctta acagaaaacc tctatgtgat atacgacctc atcctcacct
     2161 tttgctagga cagcagtaaa atctcatcaa aaagcgagta aacgaaaacc taaatgacag
     2221 gacattcgtt tactcgcttt tttgttaacc ttctatttta cacagctcat cctactaatc
     2281 tagttttctg taaaaagtgg cacgtgtgga ttgtctttat ccaacacatg cacagaagtg
     2341 attgcatgaa ggtacatttt agcgctgcct tcaatgaagt caagagcttc ttgcaatcta
     2401 ttttgacctt cttgatcaag agcttcgata atcagaaatg catttttggt gtgttctgtc
     2461 accatggtgc gttcgccatc tcgccagtta aggcaacgac aaaccgctcc aatatcatct
     2521 ttataacaca gctcatttgg caaggttggg ttgttgtcag catccccaat caagtaaaag
     2581 tcgtcaccac catctgttgt cgtcagacgc aaatctccga taaaactgtc actatcttcg
     2641 gctccaacag gtaaaccaaa acgtagacta gccgcattat aaatatccac tagtgggtta
     2701 atagacggaa tgctttgacc atttgacacc cgcttgagaa gggcttcaat gctagagcga
     2761 gctccttttt tggttttaaa gtgttgatag gccttgcggt agacttgaac cacctgatta
     2821 tcactaaaat tgtctgctgt taaataagct tttgccaact catggctatc tgctaagagc
     2881 tgtttgacat cttctggtga ctctgcttga ttctgaacat cctttaataa gacgacacct
     2941 agtttggcat ctggaaaaag ttcccaaaaa ctttgatctg ctacaaattc aaccatctct
     3001 tattctcctt tagtcccctt agttgttttc tttaagatac tctttttcct ttaaaaatgc
     3061 aattaattga gggcttaatc gtcttggccc tctcactgca gctacgccat gttttttcat
     3121 aaggtcaaaa gacaagagac catccttgta ctgttggcat tttcggagac gcatgagttt
     3181 gtcaatgtta ggatttttac gataaccctc gttaggtata tcagtttcta gaacttggca
     3241 ggcatagcga atggatttga ctggggctgt catataaatc agcacgtagt ctcccacggc
     3301 aataccagct ttttgggtcc ataaaatcac atcattggct gcaaattctg catcaatatc
     3361 atagtatttc aaattagctg gaatgaccca ataatcagga ccattaggat tagaaagacc
     3421 gtttgggttg actagttgac gactttgagt cactaacgtc caaagcttat catctgttac
     3481 cttatcatcc aaaataatac taatccagtt tttctttgac atgtgatacg ctgggtaaat
     3541 gccttcttgc tgcagtaact gaggtaagtc cttgggatta actttgacag tcatcacttc
     3601 acatgtctgt cctactaatc tctctggtat ctggtctaat ttatcagcca agagagaaaa
     3661 aatcacagca taccatttgc cctctacccg ataggttgca aggtctgggt gcttttcaaa
     3721 aggatagtcc attgggtcag accattcttt ggtgatatgc ttagcaagtc tattagcttg
     3781 cattgactga aaaggagtga cttcaaaaca ggctactgat aagcgctcca agagttccaa
     3841 ataggctgct ctaacctgcc cagtataggt tccttgccag gctgcttgtt gtaaaggcaa
     3901 ataatcctcc tccaaatcac aatcaataac ccgatcccag atattgccag cctcatcaat
     3961 cctaagctgc gcctcaaatt ctccttccat aaaccgttcg ttatagaaat aaccgttgtc
     4021 tcgcttctca aaaccgtaag ccactagctt ttcaactatg ggggtctgtc ggctaaaata
     4081 gtcagttgct aaattcatga tatcctttct aaggttctta tctccaatac cctaacttag
     4141 ggaaatggct gacatgcact tcctgtaacc ttactcgttt tcctgtgtgt cgtctgccat
     4201 taattcatgc attttaggaa gacttaattg tatttcagtg aagtggtctg actggctatg
     4261 aatggtcatg tggtagcctt caccatagtg aagttttaac cgctggtcaa cgtttttaag
     4321 gcccacacct cccctagcca acaagctctg actattggtc agtgaagagt cttcaatgcc
     4381 tttaccatta tcccaaacag tcaacatcag atgctgagct gtatcagata ccgtaacctt
     4441 gatcatgccc ttgcgatcga cttctttgat gccatggtag atagcatttt ctactaaggg
     4501 ctgtaagata agcttaggaa taacaaagtc tgcgtagaca tctaagcctt gcacttcata
     4561 acttagcttg tctccatagc gctgtttttg aataaagagg tattggctaa cgtgatccag
     4621 ttcatctgcc aaacgaatgt attcgttccc ctgattaagg gccaaacgaa aatacttagc
     4681 tagagacttg gtcacttcta ccacgcgctt gctgtcatta aattctgcca tccaaataat
     4741 agtgtccaag gtgttataga gaaaatgcgg gttaatctga ctagccaagg cttgtaacct
     4801 atactgccca atcgcctttt ccttatccgc aacggcaacc atcaagctat caatttgatc
     4861 taagagcgca ttaaactgtt gggcaaggtc tgtcaattct ggagaacctg tttcttgggc
     4921 acgtaactga cgatctcctt tttgaatagc aagaataact tgctgcaatt gttgaatggg
     4981 acgaatccat ttacgtaaga ctaaaatagt cgcaaggcca cagataagac aggctagaag
     5041 tcccatccca aggaaggacc aaaaaatctg gcgctgcacc cggtgcaact gatccagtga
     5101 cgccactccc actaaagtcc attgactgtt aggaatgagt ttttggtaaa caaaagatgt
     5161 cttgtcctta gtgtaaccat tctgaatcgc taaataaggc ttcatcgcag ccatctcctt
     5221 agaagaactg taaacactct ttttgggatg gtaaacaaat tcatgcttat cattcacaat
     5281 aaaggcaaag ccttggcggc ctagctgaag ctgatctaaa gacgctttaa cagtcgggta
     5341 tgcaatatca agtcttagca cgcctaaatt atgaccagca gcatccacta cctcttgggt
     5401 cacagaaact acccattctt ttttagaaga aagggataat tgccgagctg gggttaagat
     5461 tggcatggct tgacggtcta tggctgcttt ataccaggtt tctgccatca tatcactgga
     5521 ggttttcatg gtcaactgag gattggtaga aacggttcgg ccatccttag tcaccagaac
     5581 agctgcttgt aaatcggaat tggtcgcaag aatcatcttc atgagctgaa gaacctgttt
     5641 gtcattttct tgatgaattt gactagcaaa gtcttgaatt tccgaatttt tcgccagcac
     5701 cgaagttgtt tctttaagag gcttgatgta agcgtcaata aattgggaac tttgccgaat
     5761 gctctgccga gtatcacgtt caattaactg cctgatatta cgagaactgg tctggtaata
     5821 gagtaagccc agtgtggtaa taagggcaat tacgatcaca aagacatacg aaatcaactg
     5881 gaccagtagg ggataacgct tcatgcctgg cctccttttt tatactgact tggggtaacg
     5941 cctaccagtt gcttaaagcg ctgagaaaaa taattcatgt cctcaaagcc cacttgctcc
     6001 gcaatttcat agattttaag attactggtt aacaagagaa gcttggcttt tttcaaccgt
     6061 tcttgtacca gataatcttg aaagggcatc cctaactctt ttttaatcaa gacgctaagg
     6121 taattagggc taaaaccaag ctgctgagcc aagcttttta gggtcaaatc agaatctgcc
     6181 aaccgctcat gaatagccat tgctattgct gatacttctt tttgaggctg ctcaaccaat
     6241 tcctgaatgg tttctgtttt cttggaaagg tctaattttt gctggagctt tcctaacata
     6301 tcttccacat cggccttgga aaagggtttg agcaagtaat catctgcccc taacttcaaa
     6361 gcagataagg catagttaaa atcatcgtag cccgtcaaaa ataccagatg agtttggggg
     6421 gattcctgtt taatgagttc tgctagttga atcccattta atttgggcat attgatatcc
     6481 gtcaaaacaa tatcataagg ctctttctga aacaagtccc aagccaactg gccattttct
     6541 gcttcgttga cccgatcaat cttgaactgg ctaaaatcaa ccaaagaacg aataccttgg
     6601 cggataaggt attcgtcttc tacaattaac aatgagtaca cacggtgtct ccttatcttt
     6661 ataaagggcc ttgcatgacc ctctcatact agtctttctt ctattatatc agatttttag
     6721 gcctaaccct attctacaga tgataataaa taaccatagc ccttagcttc catatcagct
     6781 tttggaataa aggtaataga caagctattg atgcagtaac gaaggccgcc ttggtcttta
     6841 ggtccgtcag taaagacatg ccccagatga gaattccctg aacggctgcg cacttctgtt
     6901 ctcgtcatat tgaaactctt atcttccttg tagcggacaa cgtctgggct gatggggcgg
     6961 ctaaagcttg gccaaccaca acctgattca aatttgtctt ttgaagagaa aagcggttct
     7021 cctgtcacaa cgtctacgta aattcctgca tcaaaagaat cccagtagcg gtttgaaaag
     7081 gctttttcag tttcgttttt ttgcgtcact cggtattcgt ctgcagatag tttttccttg
     7141 atctcagtgg cacttggttt tgggtacttg ctttcatcaa tcacaggata agtcgcttgg
     7201 ttgatgtcaa tatggcagta gccatttgga tttttcttga ggtaatcttg gtggtagtct
     7261 tctgccttaa taaagtgttt caatggtgct ttttcaacta ctattttttt cttgtaatcc
     7321 ttagcttttt ctttgaagac ctcatcaata atagctaaat ctgccttgtc agtatagtaa
     7381 atcccagttc ggtattgact accgcgatca tttccttgct tattaagact ggttgggtca
     7441 ataattcgga aaaaatgcag taataattct ttcaagctaa tacggttcgc atcataggcc
     7501 acttcaacgg tttctgcatg accagtctga tgaattaact ggtaattagt ggtatcgcct
     7561 ctaccattgg catatcctga caccgcatct aagacgccat ccacttgtga aaaatattct
     7621 tcaacgcccc agaaacagcc accagctagg taaatcactt tttgatcaac aggggcattg
     7681 ggatctactt tagtggattt gactttttta gctggtattt gaggcttgcc ttgactaaaa
     7741 gccttggctt gacctttctg aatgagaaca gaagctccgc ctattaacaa gaccactcca
     7801 acgataaata gccataattt ccatttgtgt tccataaact caactccttt tttctaatgc
     7861 ctatcagctg gtccttccta atgtatacct ttaagggtct ttttgatgtc tgattttttg
     7921 gcataaccaa tgtgtttttt agcaagaaca ccatcacttc caatgaaaac ttctgttggg
     7981 taagatctga cgccgtaagc ttccaatagc ttgccatccg gatctaacaa gactggtaag
     8041 tccttatagt ctgttccttg gaaccatttt gtaaagtctg cttctgattt ttccccttga
     8101 tgacctggcg agacaactgt taggaccaca tagtctttat ctgacatttt agccaggtct
     8161 tcggtatctg ccaaggttga tagacagatt gaacaccaag aggcccaaaa tttcaaataa
     8221 acttttttac ctttgaactc tgataagcga taggtcttac catcaatgcc tttgagttcg
     8281 aaatcaggcg ccataggacc atcattggtc attttcttat cagatgattt atctgccatc
     8341 atggacttgt cttttgatgt tgacatctta tctttctttt tagctgccat gctcatcttg
     8401 tcctgagtta tttccttttt agccatattg tcttgggttg agcaagcagt tagtagcccg
     8461 agacaagcca aaccagttgt tactaatagt ccttttttca ttgtgtttct cctttatcca
     8521 aaaagttgtg ctaagttatt taaggttcct gtcataagca agattcccat gactataatc
     8581 agaacgcctc ctactttttt cagtaaaagt atgtggggtt tgagcttgtt aaactgtttc
     8641 aaaacaatgc ctgacgcaaa agagataagt aggaaaggaa tgcccaatcc aagagtataa
     8701 ataatcatca aaacgccacc ttgccaggca ccatttcccc ctgaagccac caaagctagg
     8761 acagaactca aaacaggtcc cacacaaggc gtccaaccaa agctaaaggt taaaccaagg
     8821 ataaatgcat tgaacaaacc gttgcgattc ttgttattat ggaaggtcag tgatttttga
     8881 aattgtaagc tcttaatggt aatgaggccc atctgatgaa tccccaagat aatgaccaag
     8941 gctcccagga aggaccgaaa ccataccgca taaaggatat ttcccaaaaa accagcccca
     9001 taacctaaaa tcacaaagat agtggataac ccaaaaatga aggctaaggt cttgacaatg
     9061 ccataccaat agagtttttt accaaatata gtaatcgtct ttgaatcatc tgcatccagt
     9121 aaaataccta aataaacagg aaggaccgga aagatacacg gagagaaaaa ggataacaag
     9181 cctgccccaa aaaccgatac cattaataca agtgatagtg tcataaataa ctcctctctt
     9241 aagttaccct tagtttaccg aaagctagtg gcgcaaacca tagactagaa catgcaaaaa
     9301 cttgaatttg atacgctatc agataaatgg ttgactaaag gcatgtaaaa acccgacctc
     9361 attaaaagag aggtcgggtt catgacgaaa atcattttcc atactatgtc aaacgttaca
     9421 gtaaataagg ctaacaagaa acagttaaat acgcttagac gcattgcgat ttctcttatg
     9481 cacataccag tacatgacaa ccataatcaa caaggctaca aggctggttg ttagtacaat
     9541 ccagaaccac acactatcaa ctttggcaaa aggcaacttc acattcatgc cataaaaact
     9601 agtaaccatg gcaataattg aaatccctat cgaaaaaatc gtcaaactgg tcacattatt
     9661 gttcaaattg ttgctgagga cgttgttata agaagacgaa atctccttga gcacacgagt
     9721 gtttaaatca cacatattag acaactgcct agcctcaata atggcatctc ggagctgctc
     9781 tgcctcatct tcttcgaggt cctgctggcc aggcatgtct tttaattctg ctagcatttg
     9841 ttcattttgc ttagacccca tgaggatgta aacagtgcca ctttgcaagt tagccaaact
     9901 ttccagattc gtcttattgg ctttttgacg caaggcttca atcaacttgt ctcgctgctg
     9961 cgctatttca tccatcagag gcacgtactg tttagtaaaa gccgttaaca gctgaaacac
    10021 caggtgacgc ggcgagcgac tctcatccaa gtcagggaaa acttcttcga ttagcgtcaa
    10081 actgtgatca tgccccaaaa tatagagaga ctgatcattc aaaaagagag taatcggaat
    10141 cacacgggga atatagttgg gatgataagc ttcttcttga cgatccaaaa tctgaaaaac
    10201 aatagtcagt ttttccttgt tttcctccat aaatgaggtt tcatttttat ctttagcgta
    10261 atcaaagacc tcagcgtcaa tgagaccttc tgagaccagt gcttcttgat cgtgctctgt
    10321 aagctgatca agattgatta acgtgattgc cgaactggct ttaggaagtg ttggcatggc
    10381 aaatctcctt tggatatctt acgcctatta tggattaaag gggtggaata cacaagtcaa
    10441 aggcttgaga atcatcttca ctgaatcgtt atttccccca agaacggtaa agtttctcaa
    10501 tcaagccaac gcccgacagg gttagggatt tggtcatcac aggactcgtc aattgacctt
    10561 ctaaaatcat ctgactgaca tgataagctt ctgcctcaaa atcactagac atggtcgcct
    10621 caatgacaga acgactccca tcaggtctga ccaaagtggc atgcgtggtt ttccaaaaat
    10681 gaggaatttc caaacgcccc ttagtcccat aaatcactag ttcatggggt aagctgagat
    10741 gagtggtcag aaaaatatcc actaaaaccc cgtttgataa agtcaaaacc agcttagact
    10801 ggctatcact ttgtccttca ggaaaatggg ctacgccact agccgacaca atatcagtat
    10861 caaagagata aggcaaataa gaaagagcgt aaggcgccat aaaatgcaca gttcccccac
    10921 ctttttccaa atctctaaac caaatcacat gatcaatatt ggggtaggcc gttgttgacg
    10981 aagccgatac aatatcaccc aattccccag cagcaatgag gctttttaaa cgctttgtca
    11041 taggaataaa gacagccttc tgagcctcca tcaaaaacaa gccgcgctct tgcgctaaag
    11101 caaaaagttc ttcagcctga gcagctgtca aggtaaacgg tttttccacc agaacatgct
    11161 tgcctgccag caaagccttc ttagccgcag gaaaatggtc ctgattgata cttgctacat
    11221 aaatggcatc aatcgacgca tccaacaaca tgtcatcaag actaccataa gccttaggca
    11281 actgatgcgc tgccgcaaaa gcctttgcct tatcaagtga ccgactggac accgccacaa
    11341 cctcgccatt gccagccaag cgcaccccct caataaaacg aggggccacc tgcgccgttg
    11401 acacaatccc ataccgaacc ttagccatcc taactccttt accatgcatt tgttaagctt
    11461 attatagcat atgtgaggga gaaagagata acaacataca ttaccacaag agatgataag
    11521 gaaggatagc gattcagtta gtcatacaaa aataagaacc ttggtaaacc aagattctta
    11581 ttaggagttc tgtaaaaaga aattattttt cggctaagcg tggtttagct tagaaaactt
    11641 aaacctagct taattggagg gtgttaaatg tttataacac ctaacgctaa caatgctgat
    11701 aatatcgacc tttacatttg ggacttattt tttgtcatct cgactagtaa acgtgtgttc
    11761 taaatcgcca cgcattagtt tttccagcac atacaacttc tcctttcatt cttgcggaga
    11821 tatcatcaaa atgctaaact aaatttaaca ttgacaacag aacacttgct ccctaaatag
    11881 tatcaataag tataccgacc agttcaaaat actactgtct tatcgtaggt aatcccccta
    11941 tctaattact ggattcaagt gatatgataa aacctacatt ttatgcatgt ttactaccat
    12001 tagaatggaa ttgttatgac caaggtaaag tattcattat tttttctcat ctatcttgta
    12061 ctaatatatc taactagtat ctactttcct gctatttata aagtcctcat gtatcttcac
    12121 tttctatgtc tattcatttt tagcattatg ttcctttata acctgattgt cattttaaaa
    12181 tatatcttta cgcataaaaa gaagtagatt aacatatatt tttgttggct cgttataaaa
    12241 ttaagttttt aaggaatgtt aaaactacta aacaaagcca aattgataga taatagaaaa
    12301 tactactaat attatgaatc attacaacat ctctagaaaa tcatgatgtg ctaaatcaaa
    12361 agatgcatgt gtttttactt gaaaaaaatt ttttatatgt gataatcata atgaatagga
    12421 atcaaaagga gaacggaatg ctaaattctg attttattat tagtaagtca cttgctaact
    12481 acattcacca tcgtaggtta gaagttggcg tgtcgtcaac tgatttggca gaaatatcca
    12541 atatgtctaa atcagattgg gaatcatttg aaaaaaatgg tggggcaatt cctttgaaat
    12601 ctaaggatat catacttgac ttattatttt tggagagatt ccctaaagag aaagaatgtg
    12661 attttataga taaattatac tatgggactt actcctgctc tctcatttat tgctggttgt
    12721 gaaatacttt ctgatgatat taataatgat ttggaggaat tatctaaact acctaaagaa
    12781 agtcatctgg gacaattaga tacttcccta cttttatcac tattgcctca acaatttatc
    12841 acaaaatatg attatgagtt tgtttataaa ttaagcaaag ttttggctca atatacatca
    12901 agaaataaag ttggttcacc ttatacagcg catagtgtaa tagaggaaat ttgtctctat
    12961 ttaattgcaa aagaatccat tctttatttt gaatctctgg acgaaaactc ccatctacaa
    13021 cttaaggaat tattagatta taacgatgag tggccttttg atatttttga tgatatggat
    13081 agctatacct ttttatatac agacatctat attgaagaag attcacttta tcactttaaa
    13141 aactggtttg tacctcaatt ttatttatag aataattgac gaaaaaatat aagaaatagg
    13201 cattaatcat ttgggtttct gcctgttttt ttatggccca atcattttca cttcttgtat
    13261 ttcagacgaa agaagtaggc atcatatatg ttgatttttc acaatctttg aatatagcaa
    13321 aaagccctgt cgcttagact gatggtctag cggcaggact ctgcggaagc aatggatgat
    13381 tttaactatt taacaagttt gtgcatctct acaatccgtt cttgggttgc gtcgtactta
    13441 gcttggtagt cagcttgttt gtctttttct ttttggacaa cttctggttt ggcgttggca
    13501 acaaagcgtt cgttgccgag ttttttgccg accatgtcca gttctttttg ccatttagcc
    13561 agttctttat ctaggcgagc gagttcttct tccacgttaa gcaaatctgc tagtggcaag
    13621 tagatttcag cacctgtgat gatgctggtc atagccagtt ctggcgcagc aatggctgag
    13681 ctgatttcta gtttttcagg gttagtgaag cgtttgatgt agttgatatt gctgttgaaa
    13741 aagtcttcta attcactatc tgctgtcttc accaaaatgg taattggttt tgatggcgcc
    13801 acatttactt ctgcacgcgc atttcgtaca gcacggataa aatctttcag actttccaca
    13861 cctttatgcg cagcctcatt ttcaaaagca ggagtaaccg tagggtatgc tgcggtcaca
    13921 atagaacctt gggcatattg ggcatagatt tcttcggtta caaatggcat gattgggtga
    13981 aggagacgca agattttgtc caaagtataa agaaggacag agcgcgtgat aactttctca
    14041 gcttcgttgt cgctatacag cacttccttg gtcaattcca cataccagtt agcaaattct
    14101 tcccagatga agttgtaaag aatgtgtcct gccacaccaa actcaaactt gtcaaagttt
    14161 tctgtcactt tagcgatggt ttcattgagg ttgtggagaa tccactggtc agtcacattt
    14221 ccagcttctg aggcagctac cttagccaca ttactttcag cttcttccaa ggtcaaccct
    14281 tcattattca tgaggatata gcgagaaatg ttccaaattt tattaatgaa attccaagag
    14341 gcgtccattt tttcgtatga gaaacgcacg tcttgtcctg gggcagagcc gtttgagagg
    14401 aaccaacgta agctatcggc accgtatttc tcaatgacat ccatcggatc aatcccgttc
    14461 cccaatgatt tagacatttt acgtccttct tcgtcacgaa taagaccgtg aatgaggaca
    14521 ttttggaacg gctgacgctc tgtaaattca a
//
LOCUS       DAXMQE010000043        14357 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.043, whole genome shotgun sequence.
ACCESSION   DAXMQE010000043 DAXMQE010000000
VERSION     DAXMQE010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14357)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14357)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14357
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.043"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            <1..1628
                     /locus_tag="ACF4ZO_001607"
     CDS             <1..1628
                     /locus_tag="ACF4ZO_001607"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004827 - proline-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA];
                     GO_process: GO:0006433 - prolyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HFD5487125.1"
                     /translation="DLWRESGRYETYGEDLYKLKNRDNSDFILGPTHEETFTTLVRDA
                     VKSYKQLPLNLYQIQSKYRDEKRPRNGLLRTREFIMKDGYSFHHNYEDLDVTYEDYRQ
                     AYEAIFTRAGLDFKGIIGDGGAMGGKDSQEFMAITPARTDLDRWVVLDKSIASMDDIP
                     KEVLEEIKAELAAWMISGEDTIAYSTESSYAANLEMATNEYKPSSKVAAEDALAEVET
                     PHCKTIDEVAAFLSVDETQTIKTLLFVADNEPVVALLVGNDHINTVKLKNYLAADFLE
                     PASEEEARAFFGAGFGSLGPVNLAQGSRIVADRKVQNLTNAVAGANKDGFHVTGVNPG
                     RDFQAEYVDIREVKEGEMSPDGHGVLQFARGIEVGHIFKLGTRYSDSMGAKILDENGR
                     AVPIVMGCYGIGVSRILSAVIEQHARLFVNKTPKGDYRYAWGINFPKELAPFDVHLIT
                     VNVKDQAAQDLTAKLEADLMAKGYDVLTDDRNERVGSKFSDSDLIGLPIRVTVGKKAA
                     EGIVEIKIKATGDSIEVNAENLIETLEILTKEH"
     gene            1881..6278
                     /locus_tag="ACF4ZO_001608"
     CDS             1881..6278
                     /locus_tag="ACF4ZO_001608"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HFD5487126.1"
                     /translation="MSDLFAKLMDQIEMPLDMRRSSAFSSADIIEVKVHSVSRLWEFH
                     FAFAAVLPIATYRELHDRLIRTFEAADIKVTFDIQAAQVDYSDDLLQAYYQEAFEHAP
                     CNSASFKSSFSKLKVTYEDDKLIIAAPGFVNNDHFRNNHLPNLVKQFEAFGFGTLTID
                     MVSDQEMTEHLTKNFVSSRQALVEKAVQDNLEAQKSLEAMMPPVEEATPAPKFDYKER
                     AAKRQAGFEKATITPMIEIETEENRIVFEGMVFDVERKTTRTGRHIINFKMTDYTSSF
                     ALQKWAKDDEELRKFDMIAKGAWLRVQGNIETNPFTKSLTMNVQQVKEIVHHERKDLM
                     PEGQKRVEFHAHTNMSTMDALPTVESLIDMAAKWGHKAVAITDHANVQSFPHGYHRAR
                     KAGIKAIFGLEANIVEDKVPISYDPVDMDLHEATYVVFDVETTGLSAMNNDLIQIAAS
                     KMFKGNIVEQFDEFIDPGHPLSAFTTELTGITDKHLQGAKPLVTVLKAFQDFCKDSIL
                     VAHNASFDVGFMNANYERHDLPKITQPVIDTLEFARNLYPEYKRHGLGPLTKRFQVSL
                     DHHHMANYDAEATGRLLFIFLKDAREKHGIKNLLQLNTDLVAEDSYKKARIKHATIYV
                     QNQVGLKNMFKLVSLSNIKYFEGIPRIPRTVLDAHREGLLLGTACSDGEVFDAVLTKG
                     IDAAVDLAKYYDFIEIMPPAIYQPLVVRELIKDQAGIEQVIRDLIEVGKRANKPVLAT
                     GNVHYLEPEEEIYREIIVRSLGQGAMINRTIGRGEGAQPAPLPKAHFRTTNEMLDEFA
                     FLGKDLAYQVVVENTQDFADRIEEVEVVKGDLYTPYIDKAEETVAELTYQKAFEIYGN
                     PLPDIIDLRIEKELTSILGNGFAVIYLASQMLVNRSNERGYLVGSRGSVGSSFVATMI
                     GITEVNPMPPHYVCPSCQHSEFITDGSVGSGYDLPNKPCPKCGTPYQKDGQDIPFETF
                     LGFDGDKVPDIDLNFSGDDQPSAHLDVRDIFGDEYAFRAGTVGTVAEKTAYGFVKGYE
                     RDYGKFYRDAEVERLAAGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAS
                     WQTTHFNFHDIDENVLKLDILGHDDPTMIRKLQDLSGIDPITIPADDPGVMALFSGTE
                     VLGVTPEQIGTPTGMLGIPEFGTNFVRGMVNETHPTTFAELLQLSGLSHGTDVWLGNA
                     QDLIKEGIATLKTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGY
                     IDAMRENNVPDWYIESCGKIKYMFPKAHAAAYVLMALRVAYFKVHHPIMYYCAYFSIR
                     AKAFELKTMSGGLDAVKARMEDITIKRKNNEATNVENDLFTTLEIVNEMLERGFKFGK
                     LDLYKSDAIEFQIKGDTLIPPFIALEGLGENVAKQIVKARQEGEFLSKMELRKRGGAS
                     STLVEKMDEMSILGNMPEDNQLSLFDDFF"
     gene            6388..6816
                     /locus_tag="ACF4ZO_001609"
     CDS             6388..6816
                     /locus_tag="ACF4ZO_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFD5487127.1"
                     /translation="MSHLDKNTALKAMVVFRKAQRTLDAFGADIFKKADLTATQFSVL
                     EVLYTKGCMRINHLIDSLLATSGNMTVVLNNMERNGWISKCKDKTDKRAYVVTLTDKG
                     TRLIEAVLPKHVARVEEAFAVLTEKEQLCLIELLKKFKQL"
     gene            6947..7489
                     /locus_tag="ACF4ZO_001610"
     CDS             6947..7489
                     /locus_tag="ACF4ZO_001610"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008752 - FMN reductase (NAD(P)H) activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0052873 - FMN reductase (NADPH) activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent FMN reductase"
                     /protein_id="HFD5487128.1"
                     /translation="MKHILFIVGSLREGSFNHQLAAQAQKALEHQAVVSYLNWKDVPV
                     LNQDIEANAPLPVVDARQAVQSADAIWIFTPVYNFSIPGSVKNLLDWLSRALNLSDPT
                     GPSAIGGKVVTVSSVANGGHDQVFDQFKALLPFIRTSVAGEFTKATVNPDAWGTGRLE
                     ISKEIKANLLSQAEALLAAI"
     gene            complement(7523..8137)
                     /gene="def"
                     /locus_tag="ACF4ZO_001611"
     CDS             complement(7523..8137)
                     /gene="def"
                     /locus_tag="ACF4ZO_001611"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042586 - peptide deformylase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HFD5487129.1"
                     /translation="MSAQDKLIKPSHLITMDDIIREGNPTLRAVAKEVSLPLCDEDIL
                     LGEKMMQFLKHSQDPVMAEKLGLRAGVGLAAPQIDVSKRIIAVLVPNLPDKEGNPPKE
                     AYSWQEVLYNPKIVSHSVQDAALSDGEGCLSVDRVVEGYVVRHARVTVDYYDKEGQQH
                     RIKLKGYNAIVVQHEIDHINGVLFYDRINAKNPFETKEELLILD"
     gene            complement(8239..8521)
                     /locus_tag="ACF4ZO_001612"
                     /pseudo
     CDS             complement(8239..8521)
                     /locus_tag="ACF4ZO_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994564.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
     gene            8647..8802
                     /locus_tag="ACF4ZO_001613"
     CDS             8647..8802
                     /locus_tag="ACF4ZO_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5487130.1"
                     /translation="MTMLGYRLSAEVRGSAILPLLAGYLIRQAIAQVYSDLKTASWLF
                     GLASSVA"
     gene            8960..9229
                     /gene="rpsO"
                     /locus_tag="ACF4ZO_001614"
     CDS             8960..9229
                     /gene="rpsO"
                     /locus_tag="ACF4ZO_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HFD5487131.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNSHIK
                     EHKKDHATYRGLMKKIGHRRNLLAYLRRTDVNRYRELIQSLGLRR"
     gene            9581..11641
                     /locus_tag="ACF4ZO_001615"
     CDS             9581..11641
                     /locus_tag="ACF4ZO_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFD5487132.1"
                     /translation="MLSHELIRNYQLFSKYKGHSLEAFESILKTSKRHILADIAKIND
                     TLSLYQLPLIALDRQLVYPPDLTEKDLLNRMLPTLDDYLFQDERLDMIIIYIMMAKEF
                     ISINHLESLLRLSRNSVIADLNLVRDRVQAFQVTLAYNRQDGYFFEGEPLALRRLLES
                     AVSSLLQVTSGPWVFSYLLHELGLPDQTKEMAATLEELSRENHLTFISEKLRDLIYFF
                     CLLAHRPFSRNVRAEAVDTFPLASPAVETMVDQLLVNFPSLTEEKYLVQSRLLGCIQG
                     DLELVFQQPIYDIMEEIINSVAVNTGLSITDTPELRQNLYSHLLPAYYRLYYDINLTN
                     PLKEQIKQDYESLFYLVKRSLSPLEKQLGKLVNEDEVAYFTIHFGRWLQAPKKRPSNQ
                     LVALSVCPNGISSSLMLEATLKELFPRLQFIRIHQLDKIKLLDPASFDLIFSTVAFDC
                     AKPVYVTQALMGPVEKMMLKKMVCDDFHLPLSEQFALDDLLSIIHKHTTITNKEGLVS
                     DLSRYLIGNHLTIEKGGLGLLDLLTADFIRQADAVSDWQEAIRLAAQPLLEHQMIETS
                     YIDGMIDSVNELGAYIVLAPKVAVPHAAPEKGARQLGMSLLQLKEPVSFDLKQEGDPD
                     KQVQLIFVLSAVDSSSHLKALQELSLILDDDEHIEQLIEAKNTEEIMSLISHMIEKGD
                     ESHD"
     gene            11634..11918
                     /locus_tag="ACF4ZO_001616"
     CDS             11634..11918
                     /locus_tag="ACF4ZO_001616"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFD5487133.1"
                     /translation="MIKIVTVCGNGIGSSLLLRMKVEAIASSLGNDVDAESCDSNAAV
                     GKGADLFVTVKEFKDIFPEDAKVCIVKSYTNRKKIEEDLVPVLKEMSGKE"
     gene            11945..13324
                     /locus_tag="ACF4ZO_001617"
     CDS             11945..13324
                     /locus_tag="ACF4ZO_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HFD5487134.1"
                     /translation="MEALLSFIRDILKEPAFLMGLIAFAGLVALKTPAHKVLTGTLGP
                     ILGYLMLAAGAGVIVTNLDPLAKLIEHGFSITGVVPNNEAVTSVAQKILGVETMSILV
                     VGLLLNLAFARFTRFKYIFLTGHHSFFMACLLSAVLGAVGFKGSLLIILGGFLLGAWS
                     AISPAIGQQYTLKVTDGDEIAMGHFGSLGYYLSAWVGSKVGKDSKDTEDLQISEKWSF
                     LRNTTISTGFIMVIFYLVATVASVLRNASVTEELAAGQNPFIFAIKSGLTFAVGVAIV
                     YAGVRMILADLIPAFQGIANKLIPNAIPAVDCAVFFPYAPTAVIIGFASSFVGGLLGM
                     LILGVAGGVLIIPGMVPHFFCGATAGIFGNSTGGRRGAMIGAFANGLLLAFLPAMLLP
                     VLGKLGFSNTTFGDVDFGVLGILLGRLGTSIGQIGIYLVVAVLAIVLVLPSFLSKSQE
                     AINNVSEEI"
     gene            13334..14065
                     /locus_tag="ACF4ZO_001618"
     CDS             13334..14065
                     /locus_tag="ACF4ZO_001618"
                     /EC_number="2.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004801 - transaldolase activity [Evidence
                     IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transaldolase"
                     /protein_id="HFD5487135.1"
                     /translation="MMTKKLNVKVFSDGAVLETMLKDLQTGLVTGFTTNPSLMKKADI
                     SSYIGFAKEVLAQITDYPVSFEVFADDLASMEKEAEKIASLGNNVYVKIPVTTSTGES
                     TCPLIQKLSAKGIKLNVTAIFTIEQTQAVVDHLTAGVPAIVSVFAGRIADTGVDPMPI
                     MEEALRICRQKEGVELLWASPRETYNIYQADQLGVDIITCTTDLIAKLPLQGKDLEDY
                     SLETVQMFLKDSTSLGFKILEDDNH"
BASE COUNT         4087 a         2717 c         3249 g         4304 t
ORIGIN      
        1 ctgatctctg gcgtgaatca ggccgttatg agacctatgg agaggacctc tataagctta
       61 aaaaccgtga taactcagac tttatcttgg gtccgaccca cgaagaaacc tttacgactt
      121 tggtgcgtga tgcggtcaaa tcttacaagc aattgccctt aaacctttat caaattcagt
      181 ctaagtatcg tgatgaaaaa cgtccgcgta atggcttgct tcgtacccgt gagtttatca
      241 tgaaagacgg ctatagtttc catcacaact atgaagattt agatgtgacc tacgaagatt
      301 atcgtcaagc ttacgaagct atttttacca gagctggtct agatttcaaa gggattattg
      361 gagatggcgg tgccatgggg gggaaagatt cccaagaatt tatggccatt acaccagctc
      421 gtacggacct tgatcgttgg gtggttcttg acaagtctat tgcgtcaatg gatgatattc
      481 caaaagaggt cttagaagag attaaggcag aattggctgc ttggatgatt tcaggtgaag
      541 atactattgc ttattcaaca gaatcaagct acgctgccaa ccttgagatg gcaactaacg
      601 aatacaaacc ttcctcaaaa gtagctgctg aagatgcctt ggcagaagtt gagacaccac
      661 attgcaaaac gattgatgaa gtggctgctt ttctttcagt agatgaaaca caaaccatca
      721 aaaccttgct ttttgtggca gataatgaac ctgttgttgc tttgctagtc ggaaatgacc
      781 atatcaatac cgttaaatta aaaaactatc tagccgctga ttttttagag ccagctagtg
      841 aagaagaagc ccgtgctttc tttggtgcag gttttggctc acttgggcct gtcaacttgg
      901 cacaaggtag tcgcattgtg gctgaccgca aagtgcaaaa ccttaccaat gccgttgcag
      961 gagctaacaa ggatggtttc catgtgacag gagtcaatcc aggacgtgac ttccaggctg
     1021 aatatgtaga tattcgtgaa gtcaaagaag gggaaatgtc tccggatggt catggtgttc
     1081 tccagtttgc gcgtggtatc gaagtgggtc atatcttcaa gttgggcact cgttattcag
     1141 acagcatggg agcaaaaatt cttgatgaga atggcagagc cgttccaatt gtcatgggat
     1201 gctatggtat cggtgttagc cgtatcctgt ctgctgtcat tgaacagcat gcccgtctct
     1261 ttgtgaacaa gacaccaaaa ggtgattacc gttatgcttg gggtattaac ttccctaaag
     1321 aattggcacc gtttgacgtg catttgatta cggttaacgt caaagaccaa gcagcacaag
     1381 acctaacggc gaagttagaa gctgacttga tggctaaagg gtatgatgtt ttgacagatg
     1441 accgtaatga acgcgtcggt tcgaaattct ctgatagcga tttgattggt ttgccaattc
     1501 gtgtcactgt tggtaaaaaa gccgctgaag gtatcgtgga aattaaaatc aaggcaacag
     1561 gtgacagcat tgaagttaat gcagaaaacc tcatcgaaac ccttgaaatt ttaacaaaag
     1621 aacactaaaa aaaaatgaag aggctgcctg tttagagcgg cctctttttg ctgtgaactt
     1681 gtctgataca gagtagcttt tgctttacca aaaacgcttg gcgataaaag attgacaaaa
     1741 aaatgatctc agctgagcta tcacttggac taaattagcc aaagaacgtc agaagaaagc
     1801 cctgcttttc tttccatcta aaactcgaaa atcatcttga attgtgataa aataaagcct
     1861 agtaaaatca ggagaaaatt atgtcagatt tattcgctaa attgatggac cagatagaaa
     1921 tgccacttga catgagacgt tcaagtgcct tttcatctgc tgatattatc gaggtaaagg
     1981 tgcattcggt gtcacgcttg tgggaatttc attttgcctt tgcggcggtt ttaccgattg
     2041 caacttatcg tgaattgcat gatcgtttga taagaacttt tgaggcggct gacattaagg
     2101 taacctttga tatccaagct gctcaggtgg attattcaga tgatctgctt caagcttatt
     2161 accaagaagc ttttgagcat gcaccgtgta atagtgctag ttttaaatct tctttctcaa
     2221 agctcaaagt gacttatgag gatgacaaac tcattattgc agcgccaggt tttgtgaata
     2281 acgatcattt tagaaacaat catctgccta atctggtcaa acaatttgaa gcctttggct
     2341 ttggcacctt gaccatagat atggtgtcag atcaggagat gactgagcat ttgaccaaga
     2401 attttgtttc cagtcgtcag gctcttgtgg aaaaggctgt gcaggataat ttggaagccc
     2461 aaaaatctct tgaagccatg atgccaccag ttgaggaagc cacacctgct cctaagtttg
     2521 actacaagga acgagcagct aagcgtcagg cagggtttga aaaagcgact atcacaccaa
     2581 tgattgagat tgagaccgaa gaaaaccgga ttgtctttga ggggatggtt tttgatgtgg
     2641 agcgtaaaac gactagaaca ggtcgccata tcatcaactt taaaatgaca gactatacct
     2701 cctcgtttgc tctccaaaaa tgggctaaag acgatgagga gctccgtaaa tttgatatga
     2761 ttgctaaggg agcttggtta cgggtacaag ggaatattga gaccaatcct tttacgaaga
     2821 gtctcaccat gaatgtgcag caggtcaaag aaattgtcca tcatgagcgc aaagacctga
     2881 tgccagaagg gcaaaagcgg gttgagtttc atgcccacac caatatgtct actatggacg
     2941 ccttaccgac agtagaaagc ttgattgata tggcagctaa atggggacac aaggcggttg
     3001 ctattaccga ccatgctaat gtgcaaagtt ttcctcatgg ctaccataga gcccgtaagg
     3061 ccgggattaa ggctattttt ggcctagaag ccaatattgt tgaggacaag gtgcctattt
     3121 cttatgatcc tgttgatatg gatttgcacg aagctaccta tgtggtcttt gacgtggaaa
     3181 ccacaggtct atctgctatg aataatgacc tgattcagat tgcggcttcc aaaatgttta
     3241 aaggaaatat tgtagagcag tttgatgaat tcattgatcc tgggcatcct ctttctgcct
     3301 ttaccaccga attgacaggg attaccgaca agcatttgca gggcgccaag ccattagtta
     3361 ccgtcctaaa agcttttcag gacttttgca aagatagtat cttggttgcc cacaacgcca
     3421 gttttgacgt gggctttatg aacgccaatt atgaacgcca cgacttgccc aaaatcacac
     3481 agcctgtgat tgatacctta gaatttgcta gaaacttgta tcctgagtac aagcgtcacg
     3541 gtttgggacc gctcaccaag cgtttccaag tgagcctaga ccaccatcat atggccaatt
     3601 acgacgcgga agccacagga cgtcttttgt ttatttttct aaaagatgcc agagaaaagc
     3661 atggcatcaa aaaccttttg caactcaata cagatttggt ggctgaggat tcttacaaaa
     3721 aagcgcggat taagcatgcg actatctatg tgcaaaatca ggttggtctt aaaaatatgt
     3781 ttaagctggt cagcctttcc aatatcaaat attttgaagg gattcctcgt attccaagaa
     3841 ccgtcttaga tgctcacaga gagggtttgt tactaggaac agcttgttct gacggcgagg
     3901 tttttgatgc cgttctgact aaaggaattg atgcggcggt tgatttggct aagtattatg
     3961 attttatcga aatcatgcca ccagccattt accagccatt ggttgttcgt gaattaatca
     4021 aagatcaagc aggtattgag caggtgattc gtgacctcat tgaagtaggg aaacgagcta
     4081 ataagccagt tcttgccact gggaatgtgc attatctaga gcctgaagaa gagatttacc
     4141 gtgaaattat tgtgcgtagt ctcggtcagg gtgccatgat taatagaaca atcggccgtg
     4201 gggaaggggc acagcctgct cctctaccta aagcgcactt tagaacaacc aatgaaatgc
     4261 tggatgagtt tgcctttctt ggaaaagacc tcgcttatca agtggttgta gaaaatactc
     4321 aggattttgc ggaccgtatt gaggaagtgg aagtggttaa gggcgatctt tacaccccgt
     4381 atattgacaa ggccgaagag acggttgccg aattaaccta tcaaaaagcc tttgaaattt
     4441 atggtaatcc tctcccagat attattgatt tacgcattga aaaagagtta acctctatct
     4501 tggggaacgg ttttgctgtg atttatctcg cttcccaaat gcttgttaac cggtcaaatg
     4561 agcgaggcta cctagttggt tctaggggat ctgtagggtc tagctttgtc gccaccatga
     4621 ttgggattac tgaggttaat cctatgccgc ctcactacgt ttgcccgtcc tgccaacatt
     4681 ctgaatttat cacagatggg tcagttggat ctggctatga tttgcctaat aaaccctgtc
     4741 cgaaatgtgg caccccttat caaaaagatg ggcaagacat tccctttgag acctttcttg
     4801 ggtttgatgg ggataaggtg cccgatattg atttgaactt ctctggtgat gaccagccca
     4861 gtgcccattt ggatgtccga gatatttttg gtgacgaata cgcctttcgt gctggaacag
     4921 ttggtaccgt agcagaaaaa acagcttatg gatttgtcaa aggctatgaa cgcgactatg
     4981 gcaagttcta tcgtgatgct gaggtggaac gtctagcagc aggtgctgct ggtgtgaaac
     5041 gaacgactgg gcagcaccct ggggggattg ttgttattcc taattacatg gatgtttatg
     5101 attttacccc cgtgcaatat ccagccgatg atgtaacggc ttcttggcag acaactcact
     5161 ttaacttcca tgatattgat gaaaacgtct tgaaacttga tatcctaggg catgatgatc
     5221 cgaccatgat tcgtaaactt caggatttat cgggcattga tcctattact attcctgctg
     5281 atgatccggg agttatggct ctcttttctg ggacagaggt tttgggcgtt accccggaac
     5341 aaattgggac accgactggt atgctaggca ttccagaatt tggaaccaac tttgttcgcg
     5401 gcatggttaa tgagacgcat ccgaccactt ttgcggagct tttgcagttg tctggactat
     5461 ctcatggaac cgatgtttgg cttggtaatg cgcaagattt gattaaagaa ggcattgcga
     5521 ccctaaaaac cgttatcggt tgtcgtgacg acatcatggt ttacctcatg cacgcaggct
     5581 tagaaccgaa aatggccttt accattatgg agcgtgtgcg taagggatta tggctgaaaa
     5641 tttctgagga agaacgtaat ggctatattg atgccatgcg agaaaacaat gtgcccgact
     5701 ggtacattga atcgtgtgga aaaatcaagt acatgttccc taaagcccat gcggcagctt
     5761 atgttttgat ggcccttcgg gtggcttatt tcaaggtgca ccaccccatt atgtattatt
     5821 gtgcttattt ctctattcgt gcgaaggctt ttgaattaaa aaccatgagt ggtggtttag
     5881 atgctgttaa agcaagaatg gaagatatta ctataaaacg taaaaataat gaagccacca
     5941 atgtggaaaa tgacctcttt acaaccttgg agattgtcaa cgaaatgtta gaacgcggct
     6001 ttaagtttgg caaattagac ctttacaaaa gtgatgctat agaattccaa atcaaaggag
     6061 atacccttat ccctccattt atagcgttag aaggtctggg tgaaaacgtg gccaagcaaa
     6121 tcgttaaagc tcgtcaagaa ggcgaattcc tctctaaaat ggaattgcgt aaacgaggcg
     6181 gggcatcgtc aacgctcgtt gagaaaatgg atgagatgag tattttagga aatatgccag
     6241 aagataatca attaagtctt tttgatgact ttttctagat tatcatgatg gtagtaatat
     6301 gcaaagtcat aaaagaagag ggacaagatc actttctaat ctctctgata ctaaactgtg
     6361 acataccgta taaagcgagg aaatcaaatg agtcatttag ataagaacac cgctttgaaa
     6421 gccatggtgg tgtttcgtaa agctcagcga acgctagatg cttttggggc tgatattttt
     6481 aaaaaggcag atttaacagc cacgcagttc agtgtgcttg aagtactata tactaaaggc
     6541 tgtatgcgaa tcaatcactt gattgattct ttgttagcga cttcggggaa tatgactgtt
     6601 gtactaaata atatggaacg taatggctgg attagcaagt gcaaagacaa aacggataaa
     6661 agagcctatg tggttacctt aacagataag ggtactcgct tgattgaagc tgttttgcct
     6721 aaacacgtcg cacgggtgga agaagccttt gctgttttga ctgaaaaaga acaactttgt
     6781 ctgattgaac ttctcaaaaa gttcaaacaa ttataaacaa atctctttac agctcttctt
     6841 agagaatata taattactac atagtgataa atttcgaaaa gaagtatcaa tgaaatacca
     6901 cttttagaaa gctttaaaac gatctttaaa aaaagaggac aaagagatga aacatatttt
     6961 atttattgtt ggctcgcttc gtgaagggtc ttttaaccat caattagcgg ctcaagcaca
     7021 aaaagctctg gaacatcaag cagttgtatc ttacttaaat tggaaagacg ttcctgtttt
     7081 gaatcaagat atcgaagcta atgcaccttt accagttgtt gacgctcgtc aagctgttca
     7141 gtcagcggat gctatctgga tttttacacc agtttacaac ttctctattc caggttctgt
     7201 taaaaacctg ctagactggt tgtctcgtgc tcttaatttg tctgatccga cgggcccatc
     7261 tgctattggc ggtaaggtgg ttacggtctc ttcagttgca aatggcgggc atgatcaagt
     7321 atttgatcag tttaaagcac tattgccgtt tatccgaact tcagtagcag gagagtttac
     7381 aaaagcaact gtgaatcctg atgcctgggg aacaggaagg cttgagattt caaaagagat
     7441 aaaagcaaac ttgctatctc aggcagaggc tcttttagcg gctatttaga ctaacaaaaa
     7501 aaggcccttt agcctttttt tgttagtcta aaatcaagag ctcttctttg gtttcaaagg
     7561 ggtttttagc attgattcga tcgtagaaca aaacaccatt gatatggtca atttcatgtt
     7621 gaaccacaat agcgttgtat ccctttaatt tgatgcgatg ctgttgtcct tctttatcat
     7681 agtagtctac tgtaacacga gcatggcgaa ccacataccc ttcaacaaca cgatcgacag
     7741 ataaacaacc ttcgccatca gaaagggctg catcttgaac agaatgagaa acgattttag
     7801 gattatacag gacttcttgc cagctatagg cttctttagg aggatttcct tctttatcag
     7861 gaagattagg aacgagcaca gcgatgatac gttttgacac atcaatctga ggagctgcta
     7921 gaccaacacc ggccctaaga ccaagttttt ccgccattac aggatcttga gaatgcttca
     7981 aaaattgcat catcttttct cctaatagga tatcctcatc acacaagggt aagctcactt
     8041 ctttggcgac agctcttaaa gttggattcc cttcacgaat aatgtcatcc atggtaatca
     8101 gatgactagg tttaattaat ttatcttgtg cagacatgtc tactccttta cttttttttt
     8161 aactggattt actatatcac aaatcatttc ttttttaaag aaaagtcaga tagtggttag
     8221 agtgattgct attataagtt aatgggctgc atacctcaga ggtctagtta ttaacactta
     8281 attgagttag agcgtctaaa tcggcaatac gataggtttt gaagcagatg cgttcgataa
     8341 tcctctgaaa aatgggctgc ttaagtacgt gcttaagatg gcgatcgctt gttccaaaac
     8401 ggtttgctaa taatgtaagg tttagatgaa cctcttggtt ggcttgcgct tcaagggtat
     8461 aggaagcaaa gcgctctttg acggtatagg taatgttttg ttggcaaaca ttttgtgtca
     8521 actcttgacc tatgtcataa aggcaggtcg catcggttaa taagctgtgt tcatggatta
     8581 gggattgggt ttgttaatac tagagcaatt aatattatca gtgaacactt tgttggaaag
     8641 aaatgaatga ctatgctagg ttaccgctta tcagctgaag tgcggggatc agccatctta
     8701 cctcttttag ctggttatct tattaggcaa gcaatcgcac aggtttattc tgatttaaaa
     8761 acagcctctt ggctatttgg ccttgctagt tctgttgctt aaggtggttt ggatgtgaga
     8821 gtttagaata ataggataac ggttgaccta atattatgaa tctgctagaa tagagtggtc
     8881 gaaagacaaa ccaacttttt cttggtttta ggagtgccaa tcctaagact cggattaagc
     8941 aaaaaaagga gaatatatta tggcaatctc aaaagagaaa aaaaatgaaa tcattgctca
     9001 atatgcacgt cacgaaggcg atactggttc agtagaagtt caagttgcag ttcttacttg
     9061 ggaaatcaac cacttgaaca gccacatcaa agaacacaaa aaagaccacg ctacttaccg
     9121 tggattgatg aagaaaatcg gtcaccgtcg taacttgttg gcatacctac gtcgtacaga
     9181 tgttaaccgt taccgtgagt tgatccaatc tcttggactt cgtcgttaat ttcaagttta
     9241 aaaagtcctc tgcttatgca gtgggctttt tcatttttga catgttgttt gttaacttac
     9301 acatttggct agaatggtct aaggctgttt ttttagcagt tgatgatttt atttaacaac
     9361 aaaaggtatc tcagtgatga ggtatctttt gttgtatcat gaagaaaaag ggaatcaatt
     9421 cccagatttg cctatttttg gccacctttt gaggaacttg ttacaatgat atcacctgtt
     9481 gagtccaatt gcagtcaaaa atgactacgg acaattggac tcaatttgtc ttgaaaatga
     9541 aaacgcttca ttttatactg acattatagg aggagatgac atgctatctc atgagctcat
     9601 cagaaactat caactctttt ctaaatataa aggacattca ctggaggcat ttgaatccat
     9661 attaaagaca agcaaacgtc atatactggc agatattgct aaaatcaatg acacgttgtc
     9721 actctatcag ttacccctta ttgctctgga caggcagctg gtttatccgc cagaccttac
     9781 tgaaaaggac ttgttgaatc gcatgctacc taccttagac gactatctct ttcaagatga
     9841 gcgtctggat atgattatca tttacatcat gatggctaaa gaatttatct ccattaacca
     9901 cttggaaagc ttgttacggc tcagcagaaa ttccgttatt gctgatttaa acttggtgcg
     9961 tgatcgggta caagcttttc aggtaacttt agcttacaat cgccaggatg gttatttttt
    10021 tgaaggagaa cccttagcct tgcggcgtct cttagaatca gcggtcagtt ctcttttgca
    10081 agttacatca ggaccttggg tgttcagtta cttattgcat gaacttggtt tgcccgacca
    10141 gacaaaggag atggcagcaa cgttggagga actgagcagg gagaaccact taacttttat
    10201 ttcggagaaa ttgagggatt tgatttattt tttctgcctt ctcgctcatc gaccattttc
    10261 acggaatgtt agggctgaag cagtggatac ttttccttta gcttcgccag ctgttgaaac
    10321 gatggtggac cagttattgg tcaacttccc cagtctaacc gaagaaaaat atttggttca
    10381 atctaggtta cttggttgta tccaaggtga cttagagtta gtctttcagc agcctatcta
    10441 tgatattatg gaggaaatca tcaattcggt ggcggttaac acgggattgt ctatcaccga
    10501 taccccagaa cttcgtcaga acttatacag tcaccttttg ccagcttatt accgacttta
    10561 ctacgacatt aacttgacca atcctttgaa ggaacaaatc aaacaagatt atgaatctct
    10621 cttttacttg gtcaagcgca gcctttctcc tctagaaaaa caattgggga aactagttaa
    10681 tgaagatgag gttgcttatt ttaccattca ttttgggaga tggttgcagg ctcctaagaa
    10741 gaggccgagc aatcagctgg tagccttatc tgtttgccct aatggcatta gttcgtctct
    10801 gatgttggag gcaaccttga aggaactttt tccacggcta cagtttatta ggattcacca
    10861 gctggacaaa ataaagttgt tggatccagc atcctttgat ttgatttttt caacagtagc
    10921 ttttgactgt gctaaacctg tttatgtgac gcaagctttg atggggcctg ttgagaaaat
    10981 gatgttgaaa aagatggttt gtgatgactt tcatcttccc ttgtcagagc aattcgcttt
    11041 ggatgacctg ttgagtatta ttcataaaca caccacgatt actaataaag aaggacttgt
    11101 tagtgattta tcccgttacc tgattggtaa ccatttaacg attgaaaaag gaggtctagg
    11161 actattggac ttgttaacag cagattttat taggcaggct gatgctgttt cggattggca
    11221 ggaagcgatt cgtttggctg ctcagccttt actagaacac cagatgattg aaacatctta
    11281 tatcgatggc atgattgatt cggtcaatga gcttggggcc tatattgttt tagcccctaa
    11341 ggttgctgtt cctcatgcgg cgcctgaaaa aggagcgcgg cagttaggca tgtctctctt
    11401 acaactaaaa gaacctgtca gctttgattt gaagcaagaa ggtgatccag acaagcaagt
    11461 gcaattgatt tttgttttgt ctgctgtgga ttctagttca catttgaagg ctttgcagga
    11521 actgtcgttg attttagatg atgatgagca tattgagcaa ttaattgagg ctaagaatac
    11581 tgaggaaata atgagtctga ttagccatat gattgaaaaa ggagatgaat cacatgatta
    11641 aaattgtaac ggtttgtgga aacggtattg gtagtagctt gttacttcgc atgaaagtag
    11701 aagctatcgc atctagtttg ggtaatgatg tggatgcaga atcctgtgac tctaatgcgg
    11761 ctgttggaaa gggtgcagat ttatttgtta ccgttaaaga atttaaagat atttttccag
    11821 aggatgccaa ggtttgtatc gttaaaagct ataccaatcg taaaaaaatt gaagaagatt
    11881 tggttccggt tctcaaggaa atgagtggca aggaataagc ctttaaagga gataggaaga
    11941 tactatggaa gcattattat catttattcg agatatttta aaagaacctg catttttaat
    12001 gggcttgatt gcctttgcag ggttggtggc tttgaaaaca cctgctcata aggtgttgac
    12061 aggaaccttg gggccaattt tgggatacct tatgcttgct gcaggggcgg gtgttattgt
    12121 gaccaatctg gaccctcttg ccaaactcat tgagcatggt tttagcatca ctggcgtagt
    12181 gccaaataac gaagccgtca cttctgtcgc tcaaaagatt ctgggtgtgg aaactatgtc
    12241 catcttggtg gttgggttat tgctcaattt ggcttttgct cgttttaccc gcttcaaata
    12301 cattttctta acaggacatc acagcttctt tatggcttgt ctcttgtccg ccgtgcttgg
    12361 agctgttggt ttcaaaggaa gtcttttgat tatcttaggt gggttcctct tgggagcttg
    12421 gtcagctatt tcgccagcca ttggtcaaca gtatactctg aaagtgactg acggagatga
    12481 aatcgccatg ggacactttg gtagtttggg ctattacctt tctgcctggg ttggtagcaa
    12541 ggttggcaaa gacagtaaag ataccgagga ccttcagatt tctgaaaaat ggagtttctt
    12601 acgcaacacc accatttcaa caggatttat catggtgatt ttctacttgg tggcaacagt
    12661 ggcttctgtt ttgaggaatg cttcagtaac agaagaatta gcagcaggtc aaaacccatt
    12721 tatctttgct attaagagtg gtcttacctt tgcggttggt gtggcaattg tctacgccgg
    12781 tgttcgcatg attttggctg acttgattcc agccttccaa ggtattgcta acaaattaat
    12841 tccaaatgct attccagctg tagactgtgc ggtattcttc ccttatgcgc caaccgctgt
    12901 tatcatcggt tttgcgtcaa gtttcgttgg tggcttactt gggatgttga ttttaggagt
    12961 tgcaggtggt gtcctgatta tcccaggtat ggtgcctcat ttcttctgcg gtgcaacagc
    13021 agggattttt ggaaattcaa caggtggtcg tcgcggtgcg atgattggtg ctttcgctaa
    13081 cggcttatta ctcgccttct tgccagccat gcttctacct gtacttggta aacttggttt
    13141 ttcaaacacg acctttggag atgtggattt cggtgtttta gggattttac tgggccgctt
    13201 aggaacgtcg attggtcaaa tcggtattta cttggtggtt gctgtgcttg ctattgtatt
    13261 ggtgcttcca agctttctgt caaaatctca agaggccatc aataatgttt cagaagaaat
    13321 ctaaaaggag gatatgatga caaaaaaact aaacgttaaa gtcttttcag acggtgcggt
    13381 cttagagacc atgttaaagg atttacaaac aggtttggtc acaggcttta caaccaatcc
    13441 aagtttgatg aaaaaagcag acatcagttc ttatattggc tttgccaaag aagtgcttgc
    13501 ccaaattaca gactacccag tgtcctttga agtctttgcg gatgatctcg caagcatgga
    13561 aaaggaagct gagaaaattg ccagtctagg taacaatgtc tatgtgaaaa ttccagtcac
    13621 cacttcaaca ggagaatcaa cctgtcccct cattcaaaag ttgtcagcta aaggcattaa
    13681 gttaaacgtc acagccattt ttacaattga gcagactcaa gctgtggttg atcatttaac
    13741 cgctggagtg ccagctattg tgtctgtttt tgctggtcgt attgcagata ccggcgttga
    13801 cccaatgcca atcatggaag aagctctacg catttgtcgt caaaaagaag gggtcgaatt
    13861 gttgtgggct agtcctcgtg aaacttataa tatctatcaa gctgatcagc taggcgtgga
    13921 cattatcact tgtaccactg atttgattgc caagttgcct cttcaaggaa aagatttaga
    13981 agactattcc cttgaaaccg tgcaaatgtt tctgaaagac agtaccagcc tcggctttaa
    14041 aattttagag gatgacaatc attaatatta ggagacgaaa gcaggcatac caacctgctt
    14101 tttttgcttt gttaaagagt ataagtttcg tttaatattt ttcaaggaca tttcaagaga
    14161 ttgcgatctg acagtgaaat ttctgctatt ttatggtaaa atgtagcaga tacgtcgttt
    14221 gatacaaaga ggagcgtgtg acaagcgtgg caggttgctt tttgtagcaa aacaacgtat
    14281 aacaactgaa tctaagcaga gaacaggtac ctctttaccc ctctgaaaat taaaaggaga
    14341 atatatgtca aaacaaa
//
LOCUS       DAXMQE010000044        14217 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.044, whole genome shotgun sequence.
ACCESSION   DAXMQE010000044 DAXMQE010000000
VERSION     DAXMQE010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14217)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14217)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14217
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.044"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            complement(<1..105)
                     /locus_tag="ACF4ZO_001619"
     CDS             complement(<1..105)
                     /locus_tag="ACF4ZO_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFD5487136.1"
                     /translation="MPRKTFDKAFKLSAVKLILEEEQSVKMVSSTLEIH"
     gene            complement(183..1493)
                     /locus_tag="ACF4ZO_001620"
     CDS             complement(183..1493)
                     /locus_tag="ACF4ZO_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HFD5487137.1"
                     /translation="MIHLIIISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNVATTNGTLDVLAQHILYRTRTHPNALYMILYLIAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSGSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYIRYSKGRTNSSLTIDQPPVLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNVAWIATYRQTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWAIIIMLCGMSLLMSLAVKSGLVTLIGHLITTTIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPTLFPIIATISAQSPHIDIRLLTTATIIGALSTNISPFSSAGSL
                     IQLSLPHIEERSLAFKKQILLGVPISLSLALLTIWILMLLASLS"
     gene            1717..2589
                     /gene="nadC"
                     /locus_tag="ACF4ZO_001621"
     CDS             1717..2589
                     /gene="nadC"
                     /locus_tag="ACF4ZO_001621"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004514 - nicotinate-nucleotide
                     diphosphorylase (carboxylating) activity [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HFD5487138.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALGDDRIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAIMLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGV
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
     gene            complement(2852..4200)
                     /locus_tag="ACF4ZO_001622"
     CDS             complement(join(2852..3750,3750..4200))
                     /locus_tag="ACF4ZO_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HFD5487139.1"
                     /translation="MKFNQETKVKIYELRQMGESIKSISKKFDMAESDLKYMIRLIDR
                     YGVTIVQKCKNNYYSPELKQEIINKVLIDGQSQKQTSLDYALPTSSMLSRWLAQYKKN
                     GYTILEKPRGGPSKMGRKRKKNLEEMTEVERLQKELEYLRAENAVLKKPERIPLERRS
                     KTQRATEIIQALRNQFPLEMLLEILDLSRSTYYYQVKRLAQGDKDIELKHVIREIYDE
                     HKGNYGYRRIYLELRNRGFLINHKKVQRLMTVMGLAARIRRKRKYSSYKGEVGKKADN
                     LIKRHFEGSKPYEKCYTDVTELALPERKLYLSPVLDGYNSEIIDFTLSRSPNLKQVQT
                     MLEKTFPADPYSGTILHSDQGWQYQHQSYHDFLESKGILPSMSRKENSPDNGMMDSFF
                     GILKSEMFYGLETTYQSLDKLEEAITDYIFYYNNKRIKAELNPFNNYLSNFLGSVHS"
     gene            4442..4570
                     /locus_tag="ACF4ZO_001623"
     CDS             4442..4570
                     /locus_tag="ACF4ZO_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002261953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HFD5487140.1"
                     /translation="MAFGENGPRKKTTFEKVTMVVVILMVLVTVGGLIASALSVLM"
     gene            4627..5940
                     /gene="obgE"
                     /locus_tag="ACF4ZO_001624"
     CDS             4627..5940
                     /gene="obgE"
                     /locus_tag="ACF4ZO_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HFD5487141.1"
                     /translation="MSMFLDTAKISVQAGRGGDGMVAFRREKYVPNGGPWGGDGGKGG
                     SVIFRVDEGLRTLMDFRYNRKFKAKSGEKGMTKGMHGRGAEDLIVFVPQGTTVRDAET
                     GKVITDLVEHGQEVVIAKGGRGGRGNIRFATPRNPAPEIAENGEPGEERQLELELKIL
                     ADVGLVGFPSVGKSTLLSVVSSAKPKIGAYHFTTIVPNLGMVRTKSGDSFAMADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHVIDMSASEGRDPYEDYVSINNELETYNLRLME
                     RPQIIVANKMDMPEAQENLKAFKKKLAAQYDEFDDLPMIFPISSLAHQGLENLLEATA
                     ELLAKTDEFLLYDEADLVDEEAYYGFAETEKDFEITRDDDATWVLSGEKLERLFVMTN
                     MERDESIMKFARQLRGMGVDEALRERGAKDGDLVRIGKFEFEFVD"
     gene            6009..6167
                     /locus_tag="ACF4ZO_001625"
     CDS             6009..6167
                     /locus_tag="ACF4ZO_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5487142.1"
                     /translation="MGDKPISFKDKDGNFVSAADVWNAEKLEELFNLLNPNRRLRLER
                     EKLKKDEA"
     gene            complement(6172..6867)
                     /gene="pnuC"
                     /locus_tag="ACF4ZO_001626"
     CDS             complement(6172..6867)
                     /gene="pnuC"
                     /locus_tag="ACF4ZO_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015663 - nicotinamide mononucleotide
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015890 - nicotinamide mononucleotide
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HFD5487143.1"
                     /translation="MAYLNYFTKTEWALWLSSVLAILISALLFGKQAPLALIASLIGV
                     TSLIFSAKANPIGQGLVIIFSIIYAYLSLRNSYYGELMTYLFMTLPMTIFSLFTWLNH
                     PFEGKKSQVTISRLTPTDRRCLFVFTILVTLIFYGILASIQTAYLLVSTLSIATSFSA
                     VYLSYKRSPYFALAYGLNDLVLILLWMHAAQTDASQYAVVICFATFLINDSYTFYSWL
                     MLQRYQEKKVKKG"
     gene            7092..8492
                     /locus_tag="ACF4ZO_001627"
     CDS             7092..8492
                     /locus_tag="ACF4ZO_001627"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFD5487144.1"
                     /translation="MKQRKHRYQFPDGFLWGSSTSGPQSEGTVPGDGKGPSNWDYWFS
                     IESAKFHHQIGPEKTSTFYENYKGDIALLKETGHTIFRTSIQWSRLIPEGVGEVNPKA
                     VTFYREVFQDIIAQGIKLIVNLYHFDLPYALQEKGGWENKATVWAYETYAKTCFELFG
                     DLVNTWITFNEPIVPVECGYLGYYHYPCKVDAKAAVQVAYNTQLASSLAVKACHKLHP
                     DHKISIVLNMTPAYPRSDAPEDVKAARIAELFQTKSFLDPSVLGVYPAELVSILEEAD
                     LLPQYSADELEVIKNNTVDFLGVNYYQPLRVQAPSKSQQEGDPLILDIYFEPYDMPGK
                     KVNPHRGWEIYEPGLYDIALNLKEHYGNIEWLVTENGMGVEGEEAFLADGQIQDDYRI
                     TFIEDHLIQLHKALGEGANCKGYLLWTFIDCWSWLNAYKNRYGLVALDLESQKRTIKK
                     SGYWFKALSESNGFDK"
     gene            8501..9595
                     /locus_tag="ACF4ZO_001628"
     CDS             8501..9595
                     /locus_tag="ACF4ZO_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HFD5487145.1"
                     /translation="MVDLGFSLYPERYDVTKSKAYIDLCHSYGAKRLFMSLLQLAPAD
                     HQMFHCYAELIAYANQLGIRVIADVSPSFISQAGWSDQLIERAHAFGLAGLRLDEALP
                     LAEIVTLTRNPFGLKIELNMSTDKQLLMSLLATDAEQSNIIGCHNFYPHEFTGLSWQH
                     FKDMSRFYHEHDIETAAFITAQSASEGPWLLAEGLPTVEDHRHLPIGLQVELMKAIGT
                     IDNILISNQFISEEELAACTQALARPVTTIKVRPIIDLTEVEEKIIGYPHCYRGDVSD
                     YVIRSTMPRLVYAQESIAPRDQSKEVKRGSIIIDNDRYHRYKGELQIALKNFTVSSKA
                     NVVAEVREDYLSLLDDLRPWQEFCLEIDPS"
     gene            9701..11695
                     /locus_tag="ACF4ZO_001629"
     CDS             9701..11695
                     /locus_tag="ACF4ZO_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFD5487146.1"
                     /translation="MLSKKELAIITFLIHHKEQFVSSATLAEVIGMSDRTVRKYLKEL
                     ISSLPEHGAHIISKQGRGYCLEIDHSMAFDIFWQESVTSKKRLADVTQVEESVDREDY
                     VLHKFFFEDAVQDFEELCQELYISRTTLKHVLAGIKERIIPYQLELEITHQHIQIRGK
                     EEDIRHFIMDYFFVTSFDNTLSTMVGNTFLEGINFAEIMIIVLDECRDAKLKLSDFVM
                     NNLVLHIALMVQRIRSGCPLELFSIPIAIRQSDEYQVALRILYRVEEVMGIRFPKEEA
                     NYIALHLKVKHSVGKHWQDDNTDEKLQDHLKACIAKISQLTGMTLETDTNLFQGLLAH
                     MMPLTTRLENHIQLTNPLTEEIKSQYPEIFTLTKQTFSDLLVCQKNDVSDDEWAYISL
                     HLMAAIERYSNRYKLRVLVVCATGYGSAMMLKNRLEKEFEGRLRIVDVISYYEITEER
                     LKTVDLIISSISLANLMFLTPVITVSVFLSNQDIETIRQFIGEQEGIKKEVSLPSQMS
                     LAKAEQLLTGVFSPNRFLYLDEKISKEDLLLRMIACLDEAGTETFVEDFYHQMVLREN
                     YSPVIYGEVLAFPHPANPMTYSEQVVVAICREPLEWDKAHQAVHFVFLLSPSKGHNHR
                     LKYVSPGLASFVNQVELQQALLEEPNYSKFMTVFTPLIHD"
     gene            11718..12029
                     /locus_tag="ACF4ZO_001630"
     CDS             11718..12029
                     /locus_tag="ACF4ZO_001630"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFD5487147.1"
                     /translation="MKSIMLVCNAGMSTSMLVTKMQKAAQVCDLEVSIWAVPVSEADN
                     EVAANSIDVLLLGPQVKFLLKDFKDKFEPDIKVDAINMADYGLMNGEKVLETALAMME
                     E"
     gene            12032..12367
                     /locus_tag="ACF4ZO_001631"
     CDS             12032..12367
                     /locus_tag="ACF4ZO_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HFD5487148.1"
                     /translation="MTEPSNLEAIMGLIMYGGEAKGKAVEAIHAARDGQFEEAQHLLQ
                     EATNSLNIAHKSQTHLLSQEAAGDAVELSLLMVHGQDHMMTALAFIDLAKELVTVYDK
                     MSAIQRGES"
     gene            12364..12798
                     /locus_tag="ACF4ZO_001632"
     CDS             12364..12798
                     /locus_tag="ACF4ZO_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HFD5487149.1"
                     /translation="MIISAEGDVSVHHCFEAMLISLQEDYRQNTLRQLSRDDIKAGIN
                     YVKHYGKYKERTVRVLITALEAPQLYTACFSSNHGIKELAYRLEALGENRTRITYSYD
                     YHPLDIFQKANHFIVGKLFKKSLERQSQAQLAALIQYAKQLQ"
     gene            12991..>14217
                     /locus_tag="ACF4ZO_001633"
     CDS             12991..>14217
                     /locus_tag="ACF4ZO_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFD5487150.1"
                     /translation="MSHFSDKFMEISGKIGSQRHLVAIRDSFISMMPITMAGSVAVLL
                     NVFLRDIPNNMGWTGFAKAMQPVIDINGYVYFGTIGIMALFFAFAFGYNLAVMHKINP
                     LAGGLISFGSFIATLPQTLTISTPLENASTNLISNLKEMGLSVVTAGGGSSIETSQWG
                     AIALKYVGATGLFTALIIGFLSSFVYAALTKRNITITLPDNVPPAVNKAFAAIIPGTV
                     AIYASAIFAYLIFALTGSSLSDVISTYIQLPLLGLSQGIGSVILLTFLVQLLWFFGLH
                     GHNVLAPVMDGIYMVALTENTAAYNTAHSAANLPYLWTRGSFDAYAQMGDSGVTLALI
                     IAIFIFSKREEHKTIAKLSAPMGVFNINEPITFGMPIVLNPTFVIPWLIVPPICASIA
                     YFATAIGLIPPVFLSVP"
BASE COUNT         4258 a         2532 c         3121 g         4306 t
ORIGIN      
        1 atgaatttct aaagttgaac taaccatttt tacagactgc tcttcctcaa ggatgagttt
       61 tacagcagag agtttgaagg ctttatcaaa ggtttttctt ggcataatga cttttcctcg
      121 tttccactta attttgtgtc tactttatta taccaagtcc aaccttaagt tagacaataa
      181 atctaactta aggaagctag cagcatgaga atccagatgg tcaagagtgc caaacttaag
      241 ctgatgggca cacccagaag aatttgtttt ttgaaagcaa gactgcgttc ctctatatgg
      301 ggaagggaga gttgaatgag ggaaccagct gatgaaaaag gagagatatt agtagataga
      361 gcgccaataa tagtggctgt tgtgagtaag cgaatatcaa tgtgaggact ttgagcactg
      421 atggtagcaa tgatgggaaa gagagttggg gctacaacgg atagggtgga actaaagagt
      481 gacatcactc cggctatcac acaaaagaac agaggtaacc agaaatgagg aatggttgtt
      541 gttatgaggt gccctatcag tgtgactaaa cctgacttga ccgctagaga cattagtaag
      601 ctcatgccgc agagcatgat aattatagcc cagggaacct tagccaaaat ggcttcttgc
      661 ttccctaatt tgagccttaa ggcgaggcag accatgagta ttgagacaaa gccaatatca
      721 aatgtttgtc gataagtagc tatccatgcg acgtttggga aaatgagatg caacaaggga
      781 aaaagccaaa ccaaaaccat gctgctgatc atgagcaagg tggtttgtct ttggaccttg
      841 ctgaggactg gtggttggtc aatagtcaag gatgagtttg ttcttccctt actgtagcgg
      901 atgtaacaag ataataaaag caagacgatg agtgggtaga taatgctgac gataaagata
      961 tgattgccaa gtgaaaaagc ttgctcttcc catcccattt gcttaaacag gccttgaaag
     1021 acaatgcctg agccactggt tatcaaatta gcccctcctg aagctcccca attgacggct
     1081 tgagctccaa tcaaagggtg tttgtccgct ttttgacaga gggtaatcgc tagaggacaa
     1141 caaacggcca tagtagtgaa aaatccagca cctaaagcag acaaaagggt tgctatcagg
     1201 tataaaatca tgtagagggc gttagggtgg gtgcgtgtgc ggtagagaat gtgttgagcc
     1261 aaaacatcaa gagtgccgtt agttgttgca acgttataaa agagagagac gctaaaaatg
     1321 gtaaaaaaga gtgaggttgg ccaaaaatga agaagttctt tggggcttaa tcccatgaga
     1381 gtggttgcga tgaggtaaga aaaagcaata gccagcaggc caatattgat tttggtgcgg
     1441 taaccaattc caatggctag agcaatggcg ctaattatta ttaagtgaat cattgaattg
     1501 tcctttagtt agaatatgaa aataggttgg caattttggc gctcaaaaga ccacctgttt
     1561 cctattggta cttgactatt atacacaaaa aaattacaat tgtcttgaca cttgttggaa
     1621 tttaaaatga ggtattcagg tttgtgattt cctacggaag ttaatagcaa ttgcctctag
     1681 tgcttacaag tgatattaaa aatagaggac ttagtgatgt caatcatttc aactgattta
     1741 accccttttc aaatagatga tacattgaaa gcagccttgc gagaagatgt tcattccgaa
     1801 gattacagta ccaatgccat ttttgatcat catggccaag ccaaggtgtc gctttttgcc
     1861 aaggaagctg gtgttttagc ggggctaacc gtttttcaaa gggtttttac cctatttgat
     1921 gccgaggtga ccttccagaa tcctcatcaa tttaaggatg gggatcgttt gactagtggc
     1981 gatttggttt tagaaatcat aggctcggtg agaagcctct taacatgtga acgcgttgcc
     2041 ttgaattttt tacaacattt atcagggatt gcttcgatga cagctgctta tgtagaagcc
     2101 ttaggcgatg atcgcattaa ggtatttgat actcgaaaaa ccactcctaa tttacgtctt
     2161 tttgagaaat atgccgtgag agttggcggt ggctataatc atcgctttaa tttatcagat
     2221 gctatcatgc taaaagacaa tcacattgcg gcagtaggta gtgttcaaaa ggcgattgct
     2281 caagcgcgtg cctatgcccc ttttgtgaaa atggtcgagg tggaagtgga aagccttgct
     2341 gctgccgaag aagctgcggc ggcgggtgtt gatattatca tgttggataa tatgtcattg
     2401 gaacagattg aacaggccat tactctaatt gcaggacgtt ctcggattga atgttctgga
     2461 aatattgata tgaccactat tagccgtttt cgtggtttag cgattgatta cgtctccagt
     2521 ggtagtttaa cccatagtgc taagagtctc gatttttcca tgaagggttt aacctacctt
     2581 gatgtctaag ttgcaaaata aactaacttt ttaaaggatg tctttcctct agaacgagtt
     2641 ttatgtcaga tagtttaaac gcctcttcaa atactttccc tgttttcacc tgattcgtgt
     2701 ccgcttatta taccaattcc aagcattcac ctgaaaaaac gatagggaga ggttagtgtt
     2761 tttattgtaa aagttccacg ccaaatccat gaagaaaatt ttgttttcag aaatcacgat
     2821 tcatcataat aaaatcaatc aaagtcgtta actaggagtg tactgacccc aaaaagttgg
     2881 acaaataatt attgaaagga tttagttctg ctttaattcg tttgttgttg tagtaaaaaa
     2941 tgtaatctgt aatagcttct tcaagcttgt caagtgattg ataagttgtc tcgagtccat
     3001 aaaacatttc agatttgaga atgccaaaga aggaatccat catgccgtta tccgggctat
     3061 tctctttgcg ggacatggat ggcaaaatac ctttagactc taaaaaatca tggtaggact
     3121 ggtgttggta ttgccacccc tggtcactat gaagaatagt tccgctgtat ggatccgctg
     3181 gaaaagtctt ctcaagcatg gtttgaacct gtttcaagtt aggagaccga gatagagtga
     3241 aatcaataat ctcactgtta tagccgtcaa gaacaggtga taagtagagt tttctttcag
     3301 gtaaggccaa ctccgtcaca tcagtgtaac atttttcgta aggtttagag ccttcgaagt
     3361 gacgtttaat cagattatca gccttcttac caacctcacc tttgtaagaa gagtacttgc
     3421 gcttacgacg aatgcgagcc gctaagccca taactgtcat caagcgttgc acctttttgt
     3481 gattgatgag gaatcctcga tttctgagtt ctaaataaat ccgacgataa ccgtaattac
     3541 ctttatgttc atcataaatc tctcgaatca catgctttag ttctatatcc ttatctcctt
     3601 gagctagtcg cttcacttga tagtaatagg tggagcgtga taaatcaagg atttcaagta
     3661 gcatctctaa gggaaattga ttccttaatg cttgaatgat ttctgttgct ctttgagttt
     3721 tgcttcgtct ctcaagcggt attctctcag cttttttagc acagcattct ccgctctaag
     3781 gtattctaat tccttctgaa gacgttcaac ctctgtcatc tcttccaaat ttttcttacg
     3841 tttacgcccc atcttactcg gtccccctct tggtttttca agaatagtat aaccgttttt
     3901 cttgtattgc gctaaccacc ttgagagcat actagaagtt ggtaaagcat aatctaagga
     3961 tgtttgtttc tgagattggc cgtcaatcag gactttattt attatctctt gcttcagttc
     4021 tggagaataa taattattct tacatttttg aacaatggtt accccatacc tatcaatcaa
     4081 gcgaatcata tatttgagat cggattctgc catatcaaac ttttttgata tggatttaat
     4141 ggactctccc atttgccgta actcataaat cttaactttc gtttcttgat taaatttcat
     4201 aaaaaaatag caccccaatc gttagatttt gtgtctaact tttggggtgc agttcaccag
     4261 acgaggaggt ttttatctgt aacattattt tgcaaatgct aatgtatcat attcatatga
     4321 aattcacaag atacaatact cagtaatagc ctacatagcg taaatattca tctgatattt
     4381 gcctaaaacg atctttcatg ttaagatata agaagaaaaa tcaatagatg aggtatttaa
     4441 cgtggcattt ggagaaaatg gacctcgcaa aaaaacaacc tttgaaaaag tgacaatggt
     4501 cgttgttatc ctaatggttc ttgtaactgt tggcgggctt attgcgagtg ccctatcagt
     4561 attaatgtaa ggaaacgctg aaaggcgttt ttttaaagta aaagaaagtt agagaataaa
     4621 aaaagtatga gtatgttttt agatacggca aaaatcagtg tccaagcagg ccgtggtggc
     4681 gatggtatgg tagcttttcg tcgtgaaaag tacgttccaa atggcggtcc ttggggagga
     4741 gacggcggta aaggtggctc agttatcttc cgagtggacg aaggtttacg taccttgatg
     4801 gatttccgct ataatcgtaa attcaaggcg aaatctggtg aaaaaggtat gaccaaaggc
     4861 atgcacggcc gtggtgcaga agatttgatt gtttttgttc ctcaagggac aacggttcgt
     4921 gatgctgaaa ctggaaaagt aattacagac ttagtagaac atggtcaaga agtggtcatt
     4981 gctaagggtg gtcgtggtgg ccgtgggaat atccgttttg caactcctcg taatcctgcg
     5041 ccagagattg ctgaaaatgg tgagccaggt gaggaacgtc agttagagtt agaactcaaa
     5101 atcttagctg acgttggctt ggtcggattc ccatctgttg ggaaatcaac cttgttaagt
     5161 gttgtgtcat cagctaaacc gaaaattggt gcctatcatt ttaccactat tgttcctaat
     5221 cttggaatgg ttcgtacaaa gtcaggtgat agctttgcta tggcagatct gccaggtttg
     5281 attgaaggtg ctagccaagg ggttggtttg ggaactcaat tcctccgtca tatcgagcgg
     5341 acacgggtta ttcttcatgt gattgacatg tctgctagtg agggtcgtga tccttacgaa
     5401 gattatgttt ctattaataa cgagctggaa acctataatt tgcgattgat ggagcgccca
     5461 cagattattg tggctaataa aatggacatg ccagaagctc aagaaaactt gaaagccttc
     5521 aagaaaaaat tggctgccca atatgacgag tttgatgacc taccaatgat ttttcctatt
     5581 tcaagcctag cacatcaagg cttagagaac ttgttagaag caacagcaga attacttgct
     5641 aagacggatg aattcttatt atatgatgaa gctgatctgg tggatgaaga agcttactat
     5701 ggctttgcag aaactgaaaa agactttgag attacccgag atgatgatgc tacttgggtc
     5761 ttgtctggtg agaaattgga acgtctcttt gtcatgacca atatggaacg tgacgaatcc
     5821 atcatgaaat ttgcccgtca attgcgcggt atgggggttg acgaagccct tcgtgaacgt
     5881 ggagcaaaag acggggatct tgttcgtatt ggcaaatttg aatttgaatt tgtggattaa
     5941 tgtggtcttt agaaatggca ttgccatagc aaccttgtgt tttatcttta agatggaggt
     6001 ttctgattat gggtgataaa ccgatatcct ttaaggataa ggatggaaat tttgtatcgg
     6061 cagcagatgt ttggaatgct gagaaattag aagaattgtt taatctttta aatcccaata
     6121 gacgtttgcg cttagaacgt gaaaaattga aaaaggatga ggcttaggcc ctcatccttt
     6181 tttgaccttt ttttcttggt aacgttggag cattagccaa ctataaaaag tgtaactatc
     6241 attaataaga aaggtggcaa agcagatgac cacagcatat tggctggcat ctgtttgagc
     6301 agcatgcatc cataagagaa tgaggactag atcattgagt ccataagcca aagcaaaata
     6361 agggcttcgc ttatagctga gataaacggc tgagaaagaa gtggcaatcg ataaagtgga
     6421 gacaagtaaa taggctgttt gaatagaagc caagatgccg tagaaaataa gagtgaccag
     6481 tatagtaaaa acgaaaagac atcttcgatc agtgggtgtt aatcgtgaaa tagtcacttg
     6541 tgattttttc ccttcaaaag gatggtttaa ccaagtaaaa agtgaaaaaa tagtcatagg
     6601 gagggtcatg aaaagatagg tcattaactc tccatagtaa ctgtttcgta atgaaagata
     6661 ggcatagata atggaaaaaa taatgacgag cccttgacca ataggattag ctttagcact
     6721 aaaaatgaga gaggtcacac caatcaaaga agctattaaa gctaagggag cttgcttacc
     6781 gaataaaagg gcgctaatta aaatggccaa gacagagctt aaccaaagtg cccactcggt
     6841 ttttgtaaag tagtttaaat aagccatacc cctattcaaa cataggctaa ggcatctgtc
     6901 aataggggct tggttttgat aagaagtagc agggcaggtt agataggctc tttaagataa
     6961 taaaatatgt caagctttaa atcacttatt ttccgtgatg ataaggaaaa aacagatttt
     7021 ttaaagcgtt tacatcacct gtttttcttc ttataataaa aagagaagtg agcaaagaaa
     7081 ggacaaagga tatgaaacaa agaaaacacc gttatcaatt tccagatggc tttttatggg
     7141 gaagttccac atctgggcct caaagcgaag gaacggttcc tggagatggc aaaggaccta
     7201 gcaactggga ttactggttt agtattgagt cagctaagtt tcatcaccaa attggtccag
     7261 aaaaaacctc aaccttttat gaaaactata aaggtgacat tgcccttttg aaagaaacag
     7321 gtcacacgat ttttcggacc tcaatccagt ggtctcgatt gattccagaa ggagtcgggg
     7381 aggttaatcc aaaggcggtg acattttacc gagaagtatt tcaagacatt attgctcaag
     7441 gtattaaatt gattgttaac ctctatcatt ttgacctccc ctatgccttg caagaaaaag
     7501 gtggctggga aaacaaagct actgtctggg cttatgaaac ctacgcaaaa acctgttttg
     7561 agctttttgg tgatttagta aacacttgga ttacctttaa tgaaccgatt gttccagtcg
     7621 aatgtggcta tttaggttat tatcactacc cttgtaaagt agatgccaag gcagcagttc
     7681 aagtggctta caacacacaa ctggccagtt cactggcggt taaagcttgt cataagcttc
     7741 atcccgacca caagattagt attgtgctta acatgacacc tgcttatcct cggagtgatg
     7801 ctcctgaaga tgtcaaggct gctagaatcg cagagctttt ccaaaccaaa tccttcctag
     7861 atccatcagt tttgggtgtg tacccagcag agttagtttc cattttagag gaagctgatt
     7921 tattacctca atatagtgct gatgaattag aggttatcaa aaacaatact gttgattttt
     7981 tgggagttaa ttattatcag cctttgcggg ttcaggcacc tagtaagtca cagcaagagg
     8041 gggaccccct tatcttagat atttattttg aaccttatga tatgcctggt aaaaaagtca
     8101 atcctcaccg gggttgggaa atttatgaac caggacttta tgatattgcc cttaatttaa
     8161 aagaacacta tggtaacatc gaatggctag tcacggaaaa tggtatgggt gtcgaaggtg
     8221 aagaagcttt tttagcagat ggccagatac aagatgacta ccgcatcacc tttatcgagg
     8281 atcatcttat ccagcttcat aaggctttgg gagaaggagc caactgcaaa ggctacctct
     8341 tgtggacttt tattgattgc tggtcttggt taaatgctta taaaaaccga tatggtttgg
     8401 tagctttgga tttagagagt caaaagcgaa ccataaaaaa atcaggttac tggtttaagg
     8461 cgttgagcga gtcaaatggt tttgataaat aggaggcaat atggttgatt taggattttc
     8521 tctataccct gagcggtatg atgttaccaa gagtaaagct tatattgact tatgtcatag
     8581 ctatggagcc aagcgcttgt ttatgagtct cttacagctg gcaccagctg atcaccagat
     8641 gtttcattgc tacgcagagc tcattgctta tgcaaatcaa ttaggcattc gagtaattgc
     8701 tgatgttagt ccaagcttta ttagccaagc tggttggtca gatcagctta ttgaacgagc
     8761 tcatgccttc gggttagcgg gcttacgctt agacgaggct ctccctctag cagagattgt
     8821 aactttaaca agaaatccct ttgggcttaa aattgaactt aatatgagca ctgataaaca
     8881 attattgatg tcattgctag cgacagatgc agaacagagc aatattattg gttgccataa
     8941 tttttatcca catgaattta ccggtttgtc atggcaacat tttaaggata tgtcacgttt
     9001 ttatcatgag catgatattg aaacggctgc ttttattacc gctcagtcag catctgaagg
     9061 cccttggcta ctggcagaag gcttgccgac agtggaagac cataggcact tgcccattgg
     9121 cctgcaagta gaattaatga aagcgatagg aaccattgat aatatcctca tatctaacca
     9181 attcatttcg gaagaagaat tggcagcatg tactcaggct ttagcaagac cagtcacgac
     9241 gatcaaggtt aggcctatca tcgatttgac agaagttgag gagaaaatca ttggctatcc
     9301 gcattgttat cgtggcgatg tatctgatta tgtgattcga tcaaccatgc cacgtctagt
     9361 ttatgctcag gaatcgattg ctccaagaga ccaatctaag gaggtcaaac gaggtagcat
     9421 tattattgac aatgaccgct atcatcgata taagggagaa ctgcaaattg ctttgaaaaa
     9481 ttttacggtt agttcaaaag ctaatgtggt tgctgaggtc agagaggact atcttagttt
     9541 gttagatgat ttgcgacctt ggcaggaatt ttgtttggag attgacccat catagattct
     9601 tttcacaatc aatgcggaaa atgatggtca cctttttcag gaaatatttg gtacactaaa
     9661 agagggtaga aagcgttttc taaagtagta aggaggacta atgttatcaa aaaaagaact
     9721 ggccatcata acatttctaa tccatcacaa agagcagttt gtctctagtg caactctggc
     9781 tgaggttatt ggtatgagtg accgtacggt taggaaatac ctcaaagaac tgatcagtag
     9841 ccttcctgaa cacggagctc acatcatttc taaacaaggt cgaggttact gcttagaaat
     9901 tgaccattct atggcatttg acatcttttg gcaagaaagt gtgacgtcta aaaaacgttt
     9961 agcagatgtg actcaagtgg aagaatcggt tgatcgagaa gattatgtgc ttcataaatt
    10021 cttttttgaa gatgccgttc aggattttga agagctttgt caagaattgt atatcagtcg
    10081 gacaacttta aaacatgttt tagcaggcat taaggaacgc ataatacctt accagttaga
    10141 gcttgaaata actcaccaac atattcaaat aagaggtaaa gaagaggaca ttaggcattt
    10201 tatcatggat tatttttttg ttactagttt tgataacacc ttgtccacca tggtaggtaa
    10261 tacctttctt gaaggtatta attttgcaga aatcatgatt attgtcttgg atgaatgtcg
    10321 ggatgctaag ttgaaacttt ctgattttgt catgaataat ctagtcttgc atattgccct
    10381 aatggttcag cgtattcgat cggggtgtcc attagaactg ttttccattc caatagctat
    10441 tcgtcagtct gatgagtatc aagtagctct gcgcattttg tatcgagtgg aagaagtgat
    10501 ggggatacgt tttcctaaag aggaggctaa ttatattgca ctgcatctaa aggtcaaaca
    10561 ttctgttggt aagcattggc aagatgataa taccgatgaa aagttgcagg accatttaaa
    10621 agcatgtatt gccaagatta gtcaattgac aggcatgact ttagaaacag ataccaattt
    10681 atttcaaggt ttattagccc acatgatgcc cttgaccaca cgtcttgaaa accatattca
    10741 gctgactaat cctttaactg aggaaattaa aagccagtat cctgaaatat ttacccttac
    10801 caagcagacc ttttcggatt tgcttgtatg tcaaaagaat gatgtctcag atgatgaatg
    10861 ggcttatatt agtttgcatt taatggcggc cattgagcgt tattcaaacc gttataaatt
    10921 gagggttcta gtagtttgtg ccacaggtta tggtagtgcc atgatgttga aaaatcgctt
    10981 ggaaaaggaa tttgaaggac gtttgcgtat tgtcgatgtt atcagttact atgaaataac
    11041 cgaagagcga ctgaaaaccg ttgatttgat tatttcctct atcagccttg ccaatctgat
    11101 gtttttaaca ccagtgatta ctgtcagtgt ttttttgtca aatcaggata ttgaaactat
    11161 tcgacaattt attggagaac aagaaggtat caagaaagag gtcagtttac cgtcacagat
    11221 gagtttagca aaagcagagc agcttctaac aggtgttttt agccctaatc gttttcttta
    11281 tttagacgag aaaatctcaa aggaagactt gcttttacgg atgattgctt gtcttgacga
    11341 ggcgggaaca gaaacgtttg tagaggactt ctatcatcaa atggtactga gggaaaatta
    11401 cagcccagtc atctatggag aagtgcttgc ctttccgcat cctgctaatc ccatgactta
    11461 ttctgaacag gtagtagtgg ctatttgccg agagcctctt gagtgggaca aggcgcatca
    11521 agctgttcat tttgtctttc tattatcccc gtctaaaggg cataatcata ggttaaaata
    11581 tgtatcacca ggtttggcat cttttgtcaa tcaggtggag cttcagcaag cgttactaga
    11641 agaaccaaat tattccaaat tcatgacagt gtttacccca cttattcatg attaaaacga
    11701 ttaaaaggag aaaccttatg aaatctatta tgttagtttg taatgccggt atgtcaacta
    11761 gtatgttggt gactaagatg caaaaagcag cccaagtgtg tgaccttgaa gtttctattt
    11821 gggcagttcc tgtgagtgaa gctgacaacg aagtggctgc taatagcatt gacgttctct
    11881 tgttaggtcc acaagtcaaa ttcttactaa aggattttaa agataagttt gaaccagata
    11941 ttaaagtaga tgccattaac atggctgatt atggtcttat gaacggtgaa aaagtccttg
    12001 aaacagccct agcgatgatg gaggagtagg catgacggaa ccatccaact tagaagctat
    12061 tatgggctta atcatgtatg gaggcgaagc caagggcaag gccgtagagg ctattcatgc
    12121 agcacgagat gggcagtttg aggaggctca gcacttactt caagaagcga caaactcgtt
    12181 aaatattgcc cataaatcgc agacacattt gctgtcccaa gaagcagctg gtgatgcggt
    12241 tgaattgtct ttattgatgg tgcatgggca agatcacatg atgactgcct tagcctttat
    12301 tgatttagcc aaggaattgg ttaccgttta cgacaaaatg tcagcaatac aaagaggtga
    12361 gtcatgatca tttcagcaga aggagatgtt tccgttcatc attgttttga agccatgctg
    12421 atatcgctcc aagaagatta tcgacaaaat accttgagac agttgtcaag agatgatatc
    12481 aaagcgggga taaactatgt taaacattat ggtaaataca aagagcgtac agtgagggtg
    12541 cttattacgg ccctagaagc tccgcaatta tatactgctt gttttagttc caatcatggg
    12601 ataaaggaat tggcttatcg attagaggct ctgggggaga atcggactag aattacctat
    12661 tcttatgact atcatcctct agatattttt caaaaagcaa atcattttat tgttggcaaa
    12721 ctgttcaaaa aaagcctaga acgccaatct caagctcagt tagcagccct tatccaatat
    12781 gctaaacagt tgcagtaacc atcgtctttg tgaagattat tcacagacct tgaatgagag
    12841 agaagggttc atttggataa gagccgatta ccggttatct ctaagcatca cgtttaacaa
    12901 ggatgatttt gagataattg tgttaggcag ataccgctgc ttttaaggtt acctttgtta
    12961 cattaaaaaa ataaaaagag gagaagattt atgtcgcatt tttctgataa gtttatggag
    13021 atttcaggaa aaattgggtc acaacggcat ttagtagcta ttcgtgattc ctttatttca
    13081 atgatgccta ttaccatggc aggttcagtt gctgtcttat tgaacgtttt tttacgcgat
    13141 attccaaaca atatgggatg gacaggattt gcaaaagcta tgcaacctgt tatcgacatc
    13201 aatggctatg tttattttgg gacaattggt atcatggcgc tcttttttgc ctttgctttc
    13261 ggttacaatt tagctgttat gcataagatt aatccattgg caggaggatt gatttctttt
    13321 ggctcattta ttgccaccct acctcagact ttaaccattt cgacaccact tgaaaatgcc
    13381 tctactaacc taattagcaa tttaaaagaa atggggcttt cagtcgttac tgcgggtgga
    13441 ggttcaagta ttgaaactag tcaatgggga gcaatagctc taaagtatgt cggtgctaca
    13501 ggcttgttca cagctttaat tattggcttt ttatcaagtt ttgtgtatgc ggctttgacc
    13561 aaacgtaata ttaccattac cttaccagat aatgtaccac ctgcggttaa taaagccttt
    13621 gctgccatta ttccaggaac agttgcgatt tacgcttcgg caattttcgc ctacctcatc
    13681 tttgcattaa caggttcttc cctaagtgat gtcatttcaa cctatatcca attaccatta
    13741 ctaggcttat cacagggtat tggttcagtt atcttgttaa ccttcttagt tcaactgctc
    13801 tggttcttcg gcttgcatgg tcataatgtc ttagccccag tgatggatgg tatttatatg
    13861 gtagctttaa cagaaaatac agctgcttac aatacagcgc atagcgctgc taatttacca
    13921 tacctttgga cacgcgggtc ctttgatgct tatgctcaaa tgggtgattc aggagtaacc
    13981 ttggcattga ttattgctat cttcatattc tcaaaacgag aagagcataa aaccattgcc
    14041 aaattgtccg caccaatggg tgttttcaat atcaacgaac caattacatt tgggatgcca
    14101 attgttttga atccaacctt tgtgattcca tggctaattg tgccaccaat ttgtgctagc
    14161 atagcttatt ttgctactgc aataggtttg attccaccgg tattcttatc agtacct
//
LOCUS       DAXMQE010000045        13708 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.045, whole genome shotgun sequence.
ACCESSION   DAXMQE010000045 DAXMQE010000000
VERSION     DAXMQE010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13708)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13708)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13708
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.045"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            <1..1098
                     /gene="ftsZ"
                     /locus_tag="ACF4ZO_001634"
     CDS             <1..1098
                     /gene="ftsZ"
                     /locus_tag="ACF4ZO_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HFD5487151.1"
                     /translation="QPEVGRKAAEESEEILTEALTGADMVFITAGMGGGSGTGAAPVI
                     ARIAKSLGALTVAVVTRPFGFEGNKRGNFAIEGIEELREQVDTLLIISNNNLLEIVDK
                     KTPLLEALSEADNVLRQGVQGITDLITSPGLINLDFADVKTVMANKGNALMGIGIGSG
                     EERIVEAARKAIYSPLLETTIDGAQDVIVNVTGGLDMTLTEAEEASEIVGQAAGQGVN
                     IWLGTSIDDTMKDDIRVTVVATGVRQEKAEQVSGFRQPRTFTQTNAQQVAGAQYASDQ
                     AKQSVQPGFDRRSNFDFDMGESREIPSAQKVISNHNQNQGSAFGNWDLRRDNISRPTE
                     GELDNHLNMSTFSANDDSDDELETPPFFKNR"
     gene            1101..1772
                     /locus_tag="ACF4ZO_001635"
     CDS             1101..1772
                     /locus_tag="ACF4ZO_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HFD5487152.1"
                     /translation="MDLLTNKKKIFETIRLSTKAANRTNDGVSVIAVTKYVDSTIAGQ
                     LIEAGIEHIAENRVDKFLEKYDALKYMPVKWHLIGTLQRRKVKEVINYVDYFHALDSV
                     RLALEINKRADHPVKCFLQVNISKEESKHGFNISEIDEAIEEIGKMEKIQLVGLMTMA
                     PANASKESIITIFRQANQLRKNLQLKKRKNMPFTELSMGMSNDYPIAIQEGSTFIRIG
                     RAFFH"
     gene            1784..2440
                     /locus_tag="ACF4ZO_001636"
     CDS             1784..2440
                     /locus_tag="ACF4ZO_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HFD5487153.1"
                     /translation="MAFKDTFNKMISYFDTDEVNEVEEDVAASTDNVIPRSQQSVRAS
                     SHPKQEPRNNHVQQDHQARSQEQTRSQMHPKHGTSERYYQQSQPKEGHEMVDRRKRMS
                     TSSIANRREQYQQSTCSDQTTIALKYPRKYEDAQEIVDLLIVNECVLIDFQFMLDAQA
                     RRCLDFIDGASKVLYGSLQKVGSSMYLLAPSNVSVNIEEMTIPHTTQDIGFDFDMKRR
                     "
     gene            2445..2699
                     /locus_tag="ACF4ZO_001637"
     CDS             2445..2699
                     /locus_tag="ACF4ZO_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HFD5487154.1"
                     /translation="MILILSILLRLIKVYTYLLIAYALMSWFPGAYDSKIGRLISGIV
                     EPILKPFRAFNLQFAGLDFTIFVVIISLNFLAQVLVRVFI"
     gene            2699..3490
                     /locus_tag="ACF4ZO_001638"
     CDS             2699..3490
                     /locus_tag="ACF4ZO_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HFD5487155.1"
                     /translation="MVSHSKIYQHFHQEEYPFIDRMSDMINRVEDYYLLEVTEFLNPR
                     EVMILKSLIALTDLKMFVSTDYYPSEYGRVIIAPGYYDLEQSDFQIALVEISYQAKFN
                     QLTHSQILGTLINELGVKRNLFGDVFVEMGYAQLMIKRELLDYFLGTITKIAKTSVKL
                     REVNFDQLIRSIDNSQTLDILVSSFRLDGVVATILKKSRTQVIALIEANKIKVNYRLA
                     NKASDNLVIGDMVSIRGHGRFTLLADNEVTKHGKQKITLSKMIHK"
     gene            3500..4258
                     /locus_tag="ACF4ZO_001639"
     CDS             3500..4258
                     /locus_tag="ACF4ZO_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HFD5487156.1"
                     /translation="MALTTLEIKDKTFKTKFRGYCEEEVNEFLDIVVDDYEALVRKNR
                     DNEARIKDLEEKLSYFDEMKESLSQSVILAQETAEKVKATANAEATNLVSKATYDAQH
                     LLDESKAKANQMLRDATDEAKRVAIETEELKRQTRVFHQRLISSIESQLSLSNSPEWD
                     ELLQPTAIYLQNSDDAFKEVVKTVLNEDIPESDDSASFDATRQFTPEELEELQRRVDE
                     SNKELEAYQLDSQSDSTTEPEVNLSETQTFKLNI"
     gene            4531..7332
                     /gene="ileS"
                     /locus_tag="ACF4ZO_001640"
     CDS             4531..7332
                     /gene="ileS"
                     /locus_tag="ACF4ZO_001640"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004822 - isoleucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006428 - isoleucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HFD5487157.1"
                     /translation="MKLKETLNLGKIAFPMRADLPNKEPQWQAAWEQAELYKKRQELN
                     AGKPAFHLHDGPPYANGNIHVGHALNKISKDIIVRSKSMSGFQAPYVPGWDTHGLPIE
                     QVLAKQGIKRKEMNLAEYLEMCRQYALSQVDKQRDDFKRLGVSADWENPYVTLDPQFE
                     ADQIRVFGAMAEKGYIYRGAKPVYWSWSSESALAEAEIEYHDIDSTSLYYANKVKDGK
                     GILDTNTYIVVWTTTPFTVTASRGLTVGPDMDYLVVKPAGSDRQYVVAEGLLDSLAGK
                     FGWESFETLASHKGADLEYIVTEHPWDTDVEELVILGDHVTLESGTGIVHTAPGFGED
                     DYNVGTKYKLEVAVTVDERGLMMENAGPDFHGQFYNKVTPIVIDKLGDLLLAQEVINH
                     SYPFDWRTKKPIIWRAVPQWFASVSDFRQDILDEIEKTTFHPSWGETRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMTKEVTDHVADLFQENGSIIWWQKEAKDLLPEGF
                     THPGSPNGEFTKETDIMDVWFDSGSSWNGVMNARENLSYPADLYLEGSDQYRGWFNSS
                     LITSVAVNGHAPYKAILSQGFVLDGKGEKMSKSKGNIISPNDVAKQYGADILRLWVAS
                     VDTDNDVRVSMEILGQVSETYRKIRNTLRFLIANTSDFNPATDTVAYADLGAVDKYMT
                     IVFNQLVATITDAYERYDFMAIYKAVVNFVTVDLSAFYLDFAKDVVYIEAANSLERRR
                     MQTVFYDILVKITKLLTPILPHTTEEIWSYLEYESEAFVQLAEMPVAETFSAQEDILE
                     AWSAFMTLRTQAQKALEEARNAKIIGKSLEAHLTIYASEEVKTLLTALDSDIALLLIV
                     SQLTIADLADAPADAVAFEGIAFMVEHAIGEVCERSRRIDPTTRMRSYNAFVCDHSAK
                     IIEENFPEAVAEGFEESGK"
     gene            complement(7596..7898)
                     /locus_tag="ACF4ZO_001641"
     CDS             complement(7596..7898)
                     /locus_tag="ACF4ZO_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HFD5487158.1"
                     /translation="MRLINTTSSHPELIRNQLKNTDAYLVEVYSAGNTDVIFTQAPKH
                     YELLISNKYRAIKEDELDIIREFFLKRKIDPKIVIPGQSKTLHTNNLIEISFQTSV"
     gene            complement(7949..8404)
                     /locus_tag="ACF4ZO_001642"
     CDS             complement(7949..8404)
                     /locus_tag="ACF4ZO_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HFD5487159.1"
                     /translation="MMIPTFGHKNAHKDYVTRYGVYAIIPNHEQTKIILVQAPNGSWF
                     LPGGEIEAGEGQLQALERELIEELGFSATIGSYYGQADEYFYSRHRDTHFYHPAYLYE
                     VTAFQAVSKPLEDFNNLGWFSPIEAIAKLKRESHQWGVKEWQKKHHSTN"
     gene            complement(8532..10814)
                     /locus_tag="ACF4ZO_001643"
     CDS             complement(8532..10814)
                     /locus_tag="ACF4ZO_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFD5487160.1"
                     /translation="MLCQNCNLNESTIHLYTSVNGKQRQVDLCQNCYQIMKSNPANSI
                     LNGLTPGYRAQDRSTSPFFDDFFGDLNNFRAFGNLPNTPPTQAGQNGNGGGRYGGNYN
                     GQRPAQPQTPNQQAKGLLEEFGINVTDIARNGNIDPVIGRDEEITRVIEILNRRTKNN
                     PVLIGEPGVGKTAVVEGLAQKIIDGTVPQKLQGKQVIRLDVVSLVQGTGIRGQFEERM
                     QKLMEEIRNRKDVILFIDEIHEIVGAGSAGDGNMDAGNILKPALARGELQLVGATTLN
                     EYRIIEKDAALERRMQPVKVDEPSVEETITILKGIQPKYEDYHHVKYSPAAIEAAAHL
                     SNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKEIDKRLIEAENLKAQATRDEDYE
                     RAAYFRDQITKYKEMQAQKVDEQDIPIITEKTIEAIVEQKTNIPVGDLKEKEQSQLVN
                     LANDLKAHVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLA
                     IELFGSTNNMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEQVRRNPYSLILLD
                     EVEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKSEASVGFGAAR
                     EGRTSSVLGELSNFFSPEFMNRFDGIIEFKALSKEHLLHIVDLMLEDVNERLGYNGIH
                     LDVTQKVKEKLVDLGYDPKMGARPLRRTIQDYIEDAITDYYLEHPTEKQLRALMTKSE
                     NITIKAVKEGDSFLNEESLD"
     gene            11113..11343
                     /locus_tag="ACF4ZO_001644"
     CDS             11113..11343
                     /locus_tag="ACF4ZO_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003105222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1797 family protein"
                     /protein_id="HFD5487161.1"
                     /translation="MESHLVRIINRLELMVTDGGNLKRNFERDGVVVAEVVFSNDPEN
                     GPVFTLRDVEARESYSFDSIDLIAMEIYDLLY"
     gene            11470..12156
                     /locus_tag="ACF4ZO_001645"
     CDS             11470..12156
                     /locus_tag="ACF4ZO_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HFD5487162.1"
                     /translation="MDLSFLPKYWAYFNYGVLVTIMISVSVVFFGTLIGVLVTLIKRS
                     HVKPLTWVVNLYVWIFRGTPMVVQIMIAFAWMHFNNMPTIGFGVLDFDFSRLLPGIII
                     ISLNSGAYISEIVRAGIEAVPKGQLEAAYSLGIRPQNAMRYVILPQAFKNILPALGNE
                     FITIIKDSALLQTIGVMELWNGAQSVVTATYSPISPLLVAAFYYLMVTTVMAQLLAVL
                     ERHMAQGGNH"
     gene            12156..12890
                     /locus_tag="ACF4ZO_001646"
     CDS             12156..12890
                     /locus_tag="ACF4ZO_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HFD5487163.1"
                     /translation="MTEAIISIKDLHKYYGHNEVLKGIDLDIMPGEVVVIIGPSGSGK
                     STLLRTMNLLEVPTKGQIRFEGIDITDKKNDIFSMREKMGMVFQQFNLFPNMTILENI
                     TLSPIKTKGVAKAEADKTALSLLDKVGLSEKAKAYPASLSGGQQQRIAIARGLAMDPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAKEVADRVIFMDGGVI
                     VEEGSPNQLFDLTKEERTKDFLSRVL"
     gene            13039..>13708
                     /locus_tag="ACF4ZO_001647"
     CDS             13039..>13708
                     /locus_tag="ACF4ZO_001647"
                     /EC_number="4.1.99.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribodipyrimidine photo-lyase"
                     /protein_id="HFD5487164.1"
                     /translation="MVSVMWFRRDLRIDVQKALAHAIASQSPTLCVFQFNKEQLNLLH
                     SRNQSSFITSVLAFRKLLKCEGIDLYLMYGDLMTCFEQLLTQLKDWTDVYFNYDESGY
                     GRLRDQKAAQFFKKNGIAVHTYQDHYLHGSQEIINQSGQPYKVFTPYYRIWQNYPKET
                     PIKVELSQGRWLNLETPDDVLRTVESIKDEKYQDVATFDEASKQLNRFIQDQLAAYHA
                     NRDFP"
BASE COUNT         4194 a         2376 c         2858 g         4280 t
ORIGIN      
        1 caacctgaag taggacgtaa agctgctgaa gaaagcgaag aaattttaac agaagctctt
       61 acaggagcgg acatggtatt tattactgcc ggtatgggtg gtggctctgg gacaggggct
      121 gcaccggtta ttgctcgtat cgctaaaagt ttgggagcct tgacagtagc tgttgttact
      181 cgcccgtttg gttttgaagg taacaaacgt ggtaattttg ctattgaagg tatcgaagaa
      241 ctacgtgaac aagttgatac tttgttaatt atttcaaata ataaccttct tgagattgtt
      301 gataaaaaga cacctttatt agaagcactt agtgaagctg ataatgtttt acgccaggga
      361 gttcaaggga taaccgactt aattactagt cctggcctta tcaatctcga ttttgccgac
      421 gtgaaaacag ttatggcaaa taaagggaat gccttgatgg ggattgggat tggctctgga
      481 gaagagcgca ttgttgaggc ggcgcgtaag gcaatctatt cacccctatt agaaacgact
      541 attgatggtg cacaagacgt tattgtgaac gttacaggag gtctcgacat gacacttaca
      601 gaagctgaag aagcctctga aattgttggg caagctgctg gtcaaggcgt taacatttgg
      661 ttaggaacat ctattgatga tactatgaaa gatgacatcc gtgtgactgt tgtagcaact
      721 ggagtgcgcc aagaaaaagc cgaacaagtt tcaggttttc gtcagcctag gacttttacc
      781 caaaccaacg cgcagcaagt agcgggtgca caatatgcat cagatcaagc aaaacagtcg
      841 gttcaaccag ggtttgatcg tcgctcaaat tttgattttg acatggggga gtctcgcgag
      901 ataccaagtg cacaaaaggt aatttctaat cataatcaaa atcaaggttc tgcttttgga
      961 aattgggatt tgagacgtga taatatttct cgtccaacag aaggtgaatt ggataaccat
     1021 cttaatatgt caacgttctc agctaacgat gacagtgatg atgaattaga aacgcctcca
     1081 ttctttaaaa accgttaata atggatttac tgacaaataa aaagaaaatt tttgagacta
     1141 tccgcttatc tacaaaggca gcaaatagga ctaatgatgg tgtttcagtt attgctgtaa
     1201 caaaatatgt ggatagtaca attgcaggtc agcttatcga agcaggaatt gagcacattg
     1261 ccgaaaaccg tgttgataaa tttcttgaaa agtatgatgc gttaaagtat atgccagtaa
     1321 agtggcattt aatcggtacc ttacaacgtc gtaaagtcaa ggaagttatc aattatgttg
     1381 attattttca cgctctagat tctgtgagat tagctttgga aatcaacaag agagctgacc
     1441 atcctgtgaa gtgttttcta caagttaata tttctaaaga agagagtaaa catggtttta
     1501 acatttctga gattgatgaa gcgattgaag aaataggtaa gatggagaag atacagttag
     1561 ttggtttaat gactatggca ccagcaaatg ccagtaaaga aagtattata actatttttc
     1621 gacaagcaaa tcaattaaga aaaaacttgc agttaaaaaa aagaaagaat atgcctttta
     1681 cagaattgag catgggcatg agtaacgatt atccaattgc tattcaagaa ggctcaactt
     1741 ttattcggat tggtagagct ttctttcact aatggagaat aagatggctt ttaaagatac
     1801 atttaacaag atgatttctt attttgacac ggatgaggtt aacgaagttg aagaagatgt
     1861 tgcagcatca actgataacg ttattccaag atcacaacaa tcagtcagag caagtagtca
     1921 tccaaaacaa gaacctagaa acaatcacgt acaacaagat catcaagcga gatcccaaga
     1981 acagacaagg tcacaaatgc atccaaaaca tggtacttct gaacgctatt atcagcagtc
     2041 tcagccaaaa gaaggccatg aaatggttga cagaagaaaa cggatgagca cttctagtat
     2101 tgcaaatcgc cgtgagcagt atcaacaatc aacttgttca gatcaaacaa ctattgcctt
     2161 aaagtatcct cgtaaatatg aggatgctca agaaattgtg gatcttttaa tagttaatga
     2221 atgcgttttg attgattttc agtttatgct agatgctcag gctagacggt gtttagattt
     2281 tattgatggt gctagtaaag tgctctatgg tagcttacaa aaggtcggct cttcaatgta
     2341 cttactggct ccgtcaaatg tatccgtcaa tatagaagaa atgactatcc cacatactac
     2401 acaagatatt ggctttgatt ttgatatgaa aaggcggtaa ataaatgata ttaatactat
     2461 ctattcttct tcgtctgatc aaagtttaca cttatttatt gattgcttac gcactaatgt
     2521 catggtttcc tggggcatat gattcaaaaa ttgggcgttt gattagtggt atcgttgaac
     2581 caattttaaa accttttaga gcatttaatt tacaatttgc cggtcttgac ttcactattt
     2641 ttgtcgtcat tattagtttg aattttttag ctcaagtttt ggtccgtgtg tttatttaat
     2701 ggttagtcat agtaagattt atcagcattt tcaccaagaa gaatatcctt ttattgatag
     2761 aatgtctgat atgattaata gagttgaaga ttactatctt ttagaagtta ctgagttttt
     2821 aaatcctaga gaagtgatga ttttaaaaag tttgattgct ttaacagatc taaaaatgtt
     2881 cgtatcaaca gattactatc caagcgaata tggtcgtgtt attattgcac ctggttacta
     2941 tgacttagaa caaagtgatt ttcaaatagc tttagtagag ataagttatc aggcaaagtt
     3001 taatcagttg acacatagtc aaattttagg aactttaatt aatgaattag gagtaaagcg
     3061 aaatttattt ggagatgttt ttgttgaaat gggatatgcc cagctcatga ttaagcggga
     3121 gttattggat tattttttag gaacaattac taaaatagct aaaactagtg tgaaattaag
     3181 agaagttaac tttgatcagt taattaggtc tattgataac agccagaccc tggatattct
     3241 agtttctagt tttcgattag atggtgtagt tgctactatc ttaaaaaaat ctcgaacgca
     3301 agttatagca ttaattgaag caaataagat taaggtaaac tatcgactcg ctaataaagc
     3361 ttcagataat ctagtcatag gggatatggt gagtatcaga ggtcacgggc gttttactct
     3421 tttagcagat aatgaagtga ccaaacatgg caaacaaaaa ataacactaa gtaaaatgat
     3481 acataaataa ggagatacaa tggcacttac aacgctagaa attaaagata aaacttttaa
     3541 gacaaaattc cgaggatact gtgaagaaga agtcaatgaa ttccttgata ttgttgttga
     3601 tgattacgaa gctcttgtac gtaaaaatcg tgataacgaa gcaagaatta aagatcttga
     3661 agaaaaatta tcttactttg atgaaatgaa agagtcactt agccagtctg taatcttagc
     3721 tcaagaaaca gctgaaaaag tgaaagcaac ggctaatgcg gaagcaacaa acttggttag
     3781 taaagcgact tatgatgctc agcatttatt agatgaatct aaagctaaag ccaatcaaat
     3841 gttgcgtgat gcaactgatg aggctaagcg agttgcgatt gaaacagaag aattaaagcg
     3901 tcaaacacgt gtgttccacc aacgtttgat ctcatctatt gagtcacaat taagcttatc
     3961 aaattcacct gaatgggatg aactgttaca accgactgca atctatcttc aaaattctga
     4021 cgatgctttt aaggaagtcg tgaagaccgt tcttaatgaa gacattcctg aatctgatga
     4081 tagtgcctct tttgatgcaa cacgtcagtt tactccagaa gagttagaag aattgcaacg
     4141 tcgtgttgat gaaagcaata aggagttaga ggcttaccaa cttgactctc aatctgattc
     4201 tacgactgag ccagaggtaa atctcagtga aacacaaacg tttaaattaa atatctaaat
     4261 aaagaaaaac aagatgattt gcttataatc acagcaagcg ggagatgatg agagtctcgt
     4321 attccctaag tattatcatt atcattttct aaaattttcg ctgaactaca gtaagcgagg
     4381 aggtttgttc accttacgag caaagaggga gcggtaagtc ttatgatata ttatcgctct
     4441 gaactaaggt ggtaccacga gctttcgtcc tttttgagac gaggcttttt tcgttatagt
     4501 cgcaagtttg tttaaaagga gtttgaaata atgaaattaa aagagacact taatctagga
     4561 aaaatagcct ttccaatgcg cgcagatctt cctaataaag agccacaatg gcaagcagct
     4621 tgggaacaag cagagcttta caaaaaacgt caagaattga atgcaggtaa gcctgccttt
     4681 catcttcatg atggacctcc ttacgctaac ggcaatattc acgttgggca tgcccttaat
     4741 aaaatttcaa aagatatcat tgtgcgttct aagtccatgt ctggctttca agcgccttat
     4801 gtacctggtt gggacacaca cggccttcca atcgaacaag tcttggctaa gcaaggaatc
     4861 aaacgtaagg agatgaattt agcagaatac cttgagatgt gtcgtcaata cgctttaagt
     4921 caggttgata aacagcgaga tgatttcaaa cggttaggtg tttcggcaga ctgggaaaat
     4981 ccttatgtca ctttggaccc acagtttgaa gctgatcaaa ttcgtgtttt tggagcgatg
     5041 gctgaaaaag gttacatcta tcgtggtgct aaacctgttt attggtcatg gtcttcagaa
     5101 tcggccttgg cagaagctga aattgaatac catgacattg attcaacctc tttatactac
     5161 gccaataaag ttaaagatgg caaaggcatc cttgatacta atacgtatat cgttgtttgg
     5221 acaacaacac catttacggt tacagcatca cgcggtttga ctgttgggcc tgatatggat
     5281 tatcttgtgg tgaaacctgc tggttcagac cgtcaatatg ttgtggcaga aggtcttttg
     5341 gatagccttg ctggaaaatt tggctgggaa tcttttgaaa ctttagccag ccataaagga
     5401 gctgatttag agtacattgt gacagaacac ccatgggata ctgacgtaga agaattggtt
     5461 atccttggtg accatgttac ccttgagtca gggacaggga ttgtccacac agcaccaggt
     5521 tttggtgagg atgactacaa tgttgggaca aaatacaaac tggaagttgc tgtgactgtt
     5581 gatgaacgtg gcctaatgat ggaaaatgca ggtccagatt tccacggaca attttataac
     5641 aaggtaacgc cgattgtcat tgataaactt ggtgatcttt tattggcaca agaagtgatc
     5701 aatcactctt acccatttga ctggcggacg aaaaaaccaa tcatctggcg tgctgtaccg
     5761 caatggtttg cttctgtttc tgatttccgt caagatattt tggatgaaat tgaaaaaaca
     5821 accttccatc catcatgggg tgaaacacgc ctttacaata tgattcgtga tcgtggcgac
     5881 tgggttattt ctcgtcaacg cgcttgggga gttccgcttc ctatcttcta tgccgaagat
     5941 ggcacagcta ttatgactaa agaagtgaca gatcatgtgg ctgatttgtt ccaagaaaat
     6001 ggatcaatca tttggtggca aaaagaagct aaagacctat taccagaggg cttcactcat
     6061 ccagggtcac caaatggcga gtttacaaaa gaaactgata tcatggacgt ttggtttgac
     6121 tctggttctt cttggaatgg agtcatgaat gctagagaaa atctttccta tccagcggat
     6181 ctctacttag aaggctctga ccagtatcgt ggttggttca attcatcctt aattacatct
     6241 gtggctgtta atgggcatgc tccatataag gctattttat cgcaaggctt tgttcttgat
     6301 ggtaagggcg aaaaaatgtc taaatcaaaa ggcaatatca tttctccaaa tgatgtggct
     6361 aaacaatatg gtgcagatat tctccgtctc tgggtagctt ctgtggatac cgataatgat
     6421 gttcgtgttt ctatggagat ccttggtcaa gtctctgaaa cttaccgtaa aatccgtaac
     6481 acccttcgct tcttgattgc taatacatct gatttcaacc ctgctacgga tacagtagct
     6541 tatgcagact taggagctgt tgataagtac atgacaattg tctttaatca gttggtagca
     6601 acgattactg acgcttatga gcgttatgac tttatggcta tttacaaagc agtggtgaac
     6661 tttgttacag ttgatttatc agccttctat cttgattttg ctaaagacgt tgtctatatt
     6721 gaagctgcca atagcttaga acgtcgtcgc atgcagacag tcttctatga tatcttggtt
     6781 aagattacca agttattgac gccaatcttg cctcacacca ctgaagaaat ctggtcttat
     6841 ctagaatatg agtcagaagc atttgttcaa ttggcagaaa tgcctgtggc agaaactttc
     6901 tcagctcaag aggatatttt agaagcttgg tctgctttca tgactttgcg tacccaagct
     6961 caaaaagctt tggaagaagc gcgaaatgct aagattatcg gtaaatcatt ggaagcccat
     7021 ttgaccatct acgctagcga agaagtgaaa accttattga ctgctttaga cagcgatatt
     7081 gctttgcttt tgatcgtgtc tcaattaacc attgctgact tggcagatgc gcctgcggat
     7141 gcagtggcat ttgaaggtat tgcctttatg gtagaacatg ccataggtga agtttgtgag
     7201 cgttcacgcc gcatcgaccc aactactcgc atgcgttctt acaatgcatt tgtctgtgat
     7261 cacagcgcta aaatcattga agaaaatttc ccagaagctg tggctgaagg gtttgaagag
     7321 agtggcaaat aagtcttatc aagacttgaa gtgacactga gtaagaagac aaccatcggg
     7381 tcttaggacc tgatggtttt ttagtagagc tgattacgtt cattagccag ctttaatgag
     7441 agacaaagta ggagaaattt agactacttt ttttatttct tttaagaaaa ttgctggctt
     7501 catataagga ctattaagat agagttcacc tttcgctaat aaaaaactta gctcttttag
     7561 aagggctaag ttttgtctga atagctggct gttgtttata cagaagtttg aaatgaaatt
     7621 tcaataaggt tattcgtgtg aagtgttttt gattgtccag gaataacaat tttaggatca
     7681 attttacgtt ttaaaaaaaa ttcgcgaatg atatcaagtt catcctcttt gatggcacgg
     7741 tatttatttg aaataagtag ttcgtaatgt tttggtgctt gggtaaaaat gacatctgta
     7801 tttcctgctg agtatacttc gactaaatag gcatcggtgt tttttagctg atttctgatg
     7861 agttctgggt gactgctagt ggtattgatg agtctcataa atgtcctcct tagtattcct
     7921 gtacctatta tagcactaat ttaaagcctt agttagtaga atgatgcttt ttttgccatt
     7981 ccttgactcc ccattgatgg ctctctcgtt ttaatttagc aattgcctcg ataggagaaa
     8041 accaacctaa gttattaaaa tcttctaagg gcttagaaac agcttgaaat gcagttactt
     8101 cataaagata ggcaggatgg tagaagtggg tatcacgatg gcgagagtag aaatattcat
     8161 cagcctgacc gtaatatgaa ccaatagtag cagaaaaacc aagttcttca atcagttcac
     8221 gctctagggc ctgaagctga ccttcacctg cttcaatttc accaccaggt aaaaaccagg
     8281 aaccattagg agcttgaaca agaataattt ttgtttgttc gtgattggga atgatagcat
     8341 agacaccgta acgtgtgaca tagtctttat gtgcattttt atgtccaaat gttggaatca
     8401 tcattttatt tacctttcct ttttcttcat tatactaaat ttttgctaat tattcttatc
     8461 aatttgttta gtttaataaa aaattgatag aaaaagagag agtctcctta tagaaactct
     8521 cttagctaac gttaatctag agactcttcg ttaagaaaag aatctccctc tttaacagct
     8581 ttaatcgtga tgttttcact ctttgtcatc agtgcacgta actgtttttc agttgggtgt
     8641 tctaaataat agtctgtaat ggcatcttcg atataatctt ggatagtacg acggagcggc
     8701 cgagcgccca ttttaggatc atagcctaaa tctactaatt tttcttttac cttttgtgtc
     8761 acatcaagat gaatcccatt atagcctaag cgctcattaa catcttccag cattaaatca
     8821 acgatatgca gcaaatgttc tttagataaa gctttgaatt caataatacc atcgaaacga
     8881 ttcataaact ctgggctgaa gaagttgctt aattcaccaa ggacagaact tgtccgtcct
     8941 tctctagcag caccaaatcc gacagaagct tcgcttttac ctgttccggc attagaggtc
     9001 atgataataa tggtgtcctt gaagctgact gttcgccctt ggccgtctgt taagcgaccg
     9061 tcatcaagaa cttgtaagaa catgtgcatg acgtcaggat gggctttttc cacctcatct
     9121 aagagaataa gggaataagg attgcgacga acttgttcgg ttagttgtcc agcttcttca
     9181 tagccgacat aacctggagg agccccgact aatttggcga cagcgtgttt ttccatgtat
     9241 tcggacatgt caaagcgaat catattgttt gtcgaaccaa agagttcaat ggctagttgt
     9301 ttagacaatt ctgttttacc aaccccagtc ggtccaacga ataagaaaga accaataggg
     9361 cgatttggag ttcctaatcc cacacggtta cgacgaatag ccttagcgat tttatcaaca
     9421 gcatcgtctt gcccgatcac gtgtgctttc agatcattgg ctaagtttac gagttgagac
     9481 tgttcctttt cttttaagtc cccaactgga atattagttt tttgctctac aatagcttca
     9541 atggtttttt cagtaatgat gggaatatct tgctcatcga ctttttgagc ctgcatttct
     9601 ttgtattttg taatttgatc gcggaaataa gctgcgcgtt catagtcttc gtctcgagta
     9661 gcttgcgcct tgagattctc agcttcaata agacgtttgt caatttcttt aggatcaaca
     9721 aagttgaggg ttagattcat tttggaacca gcttcgtcca gaaggtcaat agccttatca
     9781 ggaagaaaac ggtcttgaat atagcggtta gataaatgag cagcagcttc aatagcggct
     9841 gggctatatt tgacatgatg atagtcttcg tatttcggtt ggataccttt taaaatcgtg
     9901 atggtttcct caacagaagg ttcatcaact ttaacgggtt gcatacgtcg ctccaaggca
     9961 gcatcttttt caataatacg gtattcattt aaggtagtag caccaacgag ttgcaactca
    10021 ccacgggcca aggctggttt taaaatatta ccagcatcca tattgccgtc tcctgcagaa
    10081 ccagcaccga caatctcatg aatttcatca ataaagagaa tcacatcctt gcgattgcga
    10141 atttcttcca ttaatttttg catgcgctct tcaaactgac cacggatacc tgttccctga
    10201 acgaggctaa ccacatcaag acgaatcact tgcttgcctt ggagtttttg aggaacagta
    10261 ccatcaataa ttttttgggc caaaccttct acaacagcag ttttaccaac tccaggctca
    10321 ccaattagca caggattatt tttagtacgg cggttgagga tctcgataac gcgtgtaatc
    10381 tcttcgtcac gaccaataac aggatcaata ttaccatttc ttgcaatatc tgtgacatta
    10441 atcccaaact cttctaacaa gccctttgct tgctgatttg gtgtttgtgg ctgagcaggt
    10501 cgttgtccgt tgtagttacc accatagcgt cctccgccat ttccattttg ccctgcctga
    10561 gtaggtgggg tatttggaag attaccaaaa gctctaaaat tattcaaatc accaaaaaag
    10621 tcatcaaaga aaggacttgt ggatctatct tgtgctctat atcctggggt taggccattt
    10681 aaaatagaat tggcaggatt ggatttcatg atttgataac aattttgaca gagatcaacc
    10741 tgtctttgtt ttccattaac acttgtataa agatgaatag tagattcgtt taaattacaa
    10801 ttttgacaca gcataatata cctccgaggg tttatctaaa agtcaaagtc atttagtcaa
    10861 aaatggtcaa actttatatt catattatag caccacggct tgggaaatca agtaaaaagt
    10921 ttatcgcttt agcgttagct tttagagagt aacatgacag agtaacttta ttaagtttcc
    10981 aatgagcaaa tgtttaaaat cattgaaaag agtaaaaaaa agtaaaatat caataaatat
    11041 attactttcc ttgttagttt cccttgtttt gtgttaaaat aagagggata aaaaacgaat
    11101 aggagaaacg aaatggaatc acatttggtg agaatcatca atcgtttgga gttgatggtg
    11161 acagatggcg gtaatctcaa gcgaaatttt gaacgcgatg gtgttgttgt tgcagaagtt
    11221 gtcttttcaa atgatcctga aaatggacct gttttcacat tgcgtgatgt tgaagcgcgt
    11281 gagtcatatt cctttgatag tattgacttg attgcaatgg aaatctacga tttattatat
    11341 taagcttgac atagtaaaga gacttgcctg aggcaggttt ttttattgtc aaaaagtatt
    11401 gtattaatat tcatcagatg gtataattat ctttattgta atgaacctag gacttatgag
    11461 gagatataaa tggatttgtc atttttgccc aaatactggg cctactttaa ctacggtgta
    11521 cttgtcacca ttatgatttc agtcagcgtt gtcttttttg gaacccttat tggtgtcttg
    11581 gtaaccctga ttaagcgtag tcatgtgaag ccgttgacct gggtcgttaa tctttacgtt
    11641 tggatctttc ggggaacacc tatggtggtt caaatcatga ttgcctttgc ttggatgcat
    11701 tttaacaata tgcctactat tggttttggg gttttagact tcgacttttc aagactactt
    11761 cctggaatta ttatcatttc attgaatagc ggtgcttata tttcagaaat tgttagagca
    11821 ggtattgagg ctgtaccaaa agggcaatta gaagcagctt attcactagg tattcgtcct
    11881 caaaatgcca tgcgttatgt gattttgcct caggccttta aaaatatttt gccagcctta
    11941 ggaaatgaat ttattaccat tattaaggat agtgctcttt tacaaaccat tggagtgatg
    12001 gaactttgga atggtgccca atcggtggta acggctactt attctccaat ttccccttta
    12061 ctggtggctg ctttttacta cttaatggtc acaacagtga tggcacagtt attggcagtc
    12121 ttagaacgtc acatggcgca aggaggtaat cattgatgac tgaggctatt atttcaatta
    12181 aagacttgca caagtattat gggcacaatg aagtgcttaa gggaattgat ttagacatta
    12241 tgccaggaga ggttgtggtg attattggcc cttctggttc tggaaaatcg accttacttc
    12301 gaactatgaa tcttttggaa gtaccaacta agggacagat taggtttgag gggattgata
    12361 ttaccgataa gaagaatgat attttcagca tgcgtgaaaa aatgggaatg gttttccagc
    12421 agtttaacct ctttcccaat atgactattt tagaaaatat cactttatcg ccaatcaaaa
    12481 ctaagggagt ggctaaagca gaggctgaca aaacagcctt gagcttgttg gacaaagttg
    12541 gattatcaga aaaagccaag gcttatcctg ctagtctttc tggtgggcaa cagcagcgga
    12601 ttgcgattgc gcgtggactg gctatggatc cagatgtttt actctttgat gaaccaactt
    12661 cagctctaga cccagaaatg gtgggtgagg tcttggctgt catgcaagat ttggctaaat
    12721 ctgggatgac tatggttatt gtgactcatg aaatgggctt tgctaaagaa gtcgcagacc
    12781 gtgtgatttt tatggatggc ggcgttattg tagaagaagg aagtcctaac caactttttg
    12841 atctgactaa agaagaacgt acaaaagatt ttttgagtag agtattataa atctgttcta
    12901 tgaattataa aaggaagtcc taaatgattt aggacttcct tttataattt gctaaggcat
    12961 tttataggag attacttttc tttttgttaa aataaaaaga aatagttgca ttatttgcat
    13021 agaagaaagg gatctgttat ggtttcagtg atgtggtttc gtagagattt aaggattgat
    13081 gttcaaaaag ctttagctca tgctattgct agtcaatcac caaccttatg tgtgtttcaa
    13141 tttaacaagg agcaattaaa tctgctacat agtcggaatc aatctagttt tattactagc
    13201 gttttggctt ttagaaagtt attaaaatgt gaaggtattg acttatatct aatgtatgga
    13261 gacttaatga cctgttttga gcaattattg acacaattaa aagactggac agatgtgtat
    13321 tttaactatg atgaatctgg atatggtcgt ttacgtgatc aaaaagcagc acaatttttc
    13381 aaaaaaaatg ggattgccgt tcatacctac caagatcact atttacatgg tagtcaagag
    13441 atcattaacc aatcaggtca gccttataaa gtttttacgc cctactatag gatttggcaa
    13501 aattatccga aagagactcc tattaaagta gaactatcgc aaggcaggtg gttaaatctt
    13561 gagacaccag atgatgtttt aaggactgtt gagagcatta aagatgaaaa atatcaggat
    13621 gttgcaactt ttgatgaagc gtcaaaacaa ctaaatcgat ttattcaaga ccaattagca
    13681 gcttatcacg ctaatcgaga ttttccag
//
LOCUS       DAXMQE010000046        12584 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.046, whole genome shotgun sequence.
ACCESSION   DAXMQE010000046 DAXMQE010000000
VERSION     DAXMQE010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12584)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12584)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12584
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.046"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            <1..562
                     /locus_tag="ACF4ZO_001648"
     CDS             <1..562
                     /locus_tag="ACF4ZO_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HFD5487165.1"
                     /translation="VEMYFCADGGQSDATSMSCNIVTRVRDNGRINFRLNRVAHYYHS
                     GADTGQVKAMSTYALELKVFIDWCVKKYQMRYTEVFVDPACKSLREELHKLGVFTLGA
                     PNNSKDVSSKAKGIEVGIERGQNIISDGAFYLVNHSEEEYDHYHFLKEIGLYSRDDNG
                     KPIDKDNHAMDEFRYSINVFVHRYYN"
     gene            576..2078
                     /locus_tag="ACF4ZO_001649"
     CDS             576..2078
                     /locus_tag="ACF4ZO_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HFD5487166.1"
                     /translation="MGVIQKIKNLFTRSKYVMTTQSLTNITDHPKIAISQPEYDRITT
                     NLKYYKSDWDSVLYLNTDGETKKRGLNHLPIARTAAKKIASLVFNEQAEIKVDDDVAN
                     KFISETLKNDRFNKNFERYLESCLALGGLAMRPYVDGDKVRVAFVQAPVFLPLQSNTQ
                     DVSSAAIVIKSVKTINGKEVYYTLIEFHEWRSSDDYVISNELYRSDDNAKVGSRVPLS
                     EVYEDLKDEAKVTDVTRPIFTYLKTPGMNNKDINSPLGLSIFDNAKTTIDFINMTYDE
                     FMWEVKMGQRRVAVPESLTALTVRTADGDVIPRPRFEPDQNVYIRMGGRDLDSSAIQD
                     LTTPIRADDYIKAINEGLSLFEMQIGVSDGLFSFDGKSMKTATEIVSENSDTYQMRNS
                     IVTLVEQSLKELVISIFEIAKAYDLYQSEVPSMDNISISLDDGVFTDRDAELDYWIKV
                     VNAGFGTREMAIQKVLNVTEEKAQEIAAEINTGIVDEINQQRTDTHLYGE"
     gene            2083..3576
                     /locus_tag="ACF4ZO_001650"
     CDS             2083..3576
                     /locus_tag="ACF4ZO_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage minor capsid protein"
                     /protein_id="HFD5487167.1"
                     /translation="MKKKPIKLNDEQLLLEASQLSDMYHQLTLDLFDQVIERIKARGS
                     ASLADNPYLWQANKLHDVGLLNADNIKLIAKYSGIAEAQLRYIIKNEGFKIYKNTSEQ
                     LEEALGRESGVNSTIQDDLSNYARQAIDDVHNLTNTTLPFSVIGAYQGIIQDAVAGVV
                     TGLKTPDQAINQTVIKWFKKGFYGFTDKAGRKWRADSYARTVINTTTWRVFNEAKEAP
                     AREFGIDTFYYSKKATAREMCAPLQHQIVTTGEAREEGGIKILALSDYGHGEPDGCLG
                     INCKHTKTPFVVGVNSKPELPEHLKNITPAQAKANANAQAKQRAIERSIRKSKELLHV
                     AKQLGDKELIRQYQSDVRSKQDALNYLINNNAFLHRNQAREKRYNNPYTKTQSEVEVR
                     KEKAKLDKRRDVESAIIGVEASEGIPLKITKHLAERAVLRNIAPIDIVDSIKEPLKIA
                     PIKYDNLDRPSQKYIGKCVSTVINPIDGNIVTVHATSTRIRKKYGGN"
     gene            3576..3803
                     /locus_tag="ACF4ZO_001651"
     CDS             3576..3803
                     /locus_tag="ACF4ZO_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5487168.1"
                     /translation="MKLKSILNDSQIDFVKNELPGLPVDIDVNSEKYDVFCEGIETYY
                     QTESFDEKYNITAKGKLAESIIDLLTDKGYW"
     gene            3890..4156
                     /locus_tag="ACF4ZO_001652"
     CDS             3890..4156
                     /locus_tag="ACF4ZO_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5487169.1"
                     /translation="MNKRIKKKRKLETAVVMLVAENAMQVEAIKNQNKQIMELKSIVQ
                     RNALATNEELATVKAATLDNQSVIKAIGDTVDYIKKNYKRKWGK"
     gene            4282..4896
                     /locus_tag="ACF4ZO_001653"
     CDS             4282..4896
                     /locus_tag="ACF4ZO_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5487170.1"
                     /translation="MHMENVTNENVDQETTDLENNQQEDKAFTQDDLNRVGTKEHSKG
                     YNKAVKDLGFDDVESAKDALKAFQEWQESQRSESEKQTEILNAKDKELEEARANNKAL
                     NAKLAAMSLGVNAESIDDVIALSERLVTDETSIEDAIKTVLGKYPHFGQTKDKAPKIT
                     VAGNPSADNGQGSVSKEDFAKMSYQEKLDLKLKNKNLYDQLKGN"
     gene            4900..5718
                     /locus_tag="ACF4ZO_001654"
     CDS             4900..5718
                     /locus_tag="ACF4ZO_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0019028 - viral capsid [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N4-gp56 family major capsid protein"
                     /protein_id="HFD5487171.1"
                     /translation="MAVGTTKMAQMLDPEVLADMIDAEVGKAIRFAPLAEVDTTLEGQ
                     PGTTLTVPKWDYIGDAEDVAEGEAIPMTQLGFKKTTMTIKKAGKGVEITDEAILSGYG
                     DPVGQAAKQIVEAIDHKVDADVLDALSKSTQTVEATATVDGVSKALDIFNDEDDAETV
                     IVMNPADASTLRLDAAKEWLGATEVGANRVVSGVYGEVLGVQIVRSRKCPKGTAYMVR
                     KGALRIMLKRNTMVETDRDITKAINQIVANKHYGVYLYKAEKAVKITLKDAAKK"
     gene            5772..6188
                     /locus_tag="ACF4ZO_001655"
     CDS             5772..6188
                     /locus_tag="ACF4ZO_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008088495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5487172.1"
                     /translation="MEVVIIAFLTQKEFEDLGFDEVEYFEKMEKRASHAVNLYCRNRY
                     DYKDLKKEIALVQKAVKRAIAYQIAYLNDSGVMTAEDKQSFAGISLGRTSISYTVGHG
                     QGSQQKTLADRFNLCLDAENELLAVGLGYTGISYDR"
     gene            6178..6510
                     /locus_tag="ACF4ZO_001656"
     CDS             6178..6510
                     /locus_tag="ACF4ZO_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HFD5487173.1"
                     /translation="MIDKRLLIDELQVKLVKDKGDYGGFVYDEPFTLSPVRFDRNLAT
                     AGKDNARQETKPSVIFIYPKYCKTVADRSWVDAVVIDGDTEYTVDKVIPVYHPLTNKI
                     FCFEVEVI"
     gene            6510..6866
                     /locus_tag="ACF4ZO_001657"
     CDS             6510..6866
                     /locus_tag="ACF4ZO_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HFD5487174.1"
                     /translation="MAKVVVELGGIKRKVSPQALAKGKLIMNNQVMMSMNPYVPYRDG
                     ALRGSSRANSVGVTWSGPHARAQFYGGAYNKYKSFKFKKYTTPGTGKRWDKRALANAT
                     IVKDWEKSLLRGMGFK"
     gene            6863..7261
                     /locus_tag="ACF4ZO_001658"
     CDS             6863..7261
                     /locus_tag="ACF4ZO_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HFD5487175.1"
                     /translation="MTNDFATVLRQFVEGLDLGIKPRLDYLTRQEDLAIYPMPGGKVN
                     NEYMDGTREISLPFEIAIKTKNQELASTVMWTINSALSNFDLKLPSLNHSYTFISLDV
                     EKPFLNDLSDQGFYIYVLDITAHLEIEGKN"
     gene            7261..7722
                     /locus_tag="ACF4ZO_001659"
     CDS             7261..7722
                     /locus_tag="ACF4ZO_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFD5487176.1"
                     /translation="MARQKNALRGHFIAPYNAGVEPEAKGSEWMEIAKWIKDISDDTD
                     EKTEDEAYYDGDGTEETTVVGVKGAYTFEGTYDPEDKAQKHIADMKYKTGEGRKVWHK
                     VVASDNKKQWIGLSTVSEIIAGSGAAADFEAFSCKITYNSLPKESVPSEVL"
     gene            7766..8200
                     /locus_tag="ACF4ZO_001660"
     CDS             7766..8200
                     /locus_tag="ACF4ZO_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5487177.1"
                     /translation="MSEIVVDLKRTGFPVKIGQVELWFDTSQERLIEFFDIETEVKRR
                     LNEYEKQVIEANLDNEIEDKGVTKDVAQSALDLEAKYLEINYDLLFGEGTFAQLYAEY
                     PDKEALENTLEIVCREIEVKLKELAIEREKIVKQKMKKYKKG"
     gene            8204..8785
                     /locus_tag="ACF4ZO_001661"
     CDS             8204..8785
                     /locus_tag="ACF4ZO_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriophage Gp15 family protein"
                     /protein_id="HFD5487178.1"
                     /translation="MKLNDPLVESFEFRGEIYSINLSFNKVLDVFDVIDDDFLNEAEK
                     CFLCLDILLDRTDLPFSYAVDLWIHIKKNYIDTKKSEKPQLDIKGNPMPVVKEKEDNE
                     KVIDLRLDAEFIYASFRQAYQINLLKEQNRLSWIEFKALLNALPDDTVMQRIIAIRQW
                     EDDGEGSKKYRDNMRKLKAKYSLDEGEEEDDGS"
     gene            8775..12035
                     /locus_tag="ACF4ZO_001662"
     CDS             8775..12035
                     /locus_tag="ACF4ZO_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015967413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HFD5487179.1"
                     /translation="MAADGKVTILIDVDGKQVKVLNSELDKVAKHGDKGSSSLKKFAV
                     GAGVFKLASAAVDLVSQSLGKAITRFDTLEKYPRVMKAMGHSAEDVARSTDKLANGID
                     GLPTTLDEVVGTAQRLTSITKDINKSTNLTLALNNAFLASGASSEAASRGLEQYAQML
                     SAGKVDMQAWKTLQETMPYALQQTAEAFGFAGASAQKDFYEALKNGQITFDQFSNKLI
                     ELNDGVGGFAELAKENSKGIETSFNNIKNAIAKGVANSIKALDDLSKAATGKGIADHF
                     DSLKVVINASFSAINASIKASTPLFKLLFSVIGAGISVVKALSPALVGVASGLAAMRA
                     VNETITMIKALNRAWVMASASMSIGATTIKTVTAVQAVSTTMTKADMVARLSQLGVLK
                     ASTVIYGVMTGAISLSTAATIASTAAVTALKAALVALTGPVGWVVGAIGALVAVGVSL
                     WSWLTKESDETKKLKKEQEGLVESNKQLRDSVREGVQERKKGLESVKESTAAHQKLAD
                     EIIKLAAKENKTAGEKQNLKNKIDQLNGSIDGLNLAYDKNSNSLSHNADQIKSRISAM
                     EAESTWQTAQQNLLNIEQKRSEVSKKLAENADLRKKWNEEANVSDSVRKEKIAELTEE
                     EAKLKNMQTQLQEEYNKTSATQQAAADAMAAAEESGSARQVIAYENMSEAQRTAIDNM
                     RTKYSELLETTTSIFDAIEQKTALSVDQMNTNLEKNRAATEQWATNLEILAQRGVDQG
                     ILEQLRRMGPEGATQTQVFVDATDAELAPLQENFRAATETAKNAMGSVLDSAGVEMPE
                     KVKGMVTNVSTGLQAELQAANFAQLGQEIPNGVSQGISQGAGKASDASVKMGQEVKRS
                     FQGELGIHSPSRVFTEYGGHITDGLSNGVTNGTSKVMQTMQSLAQQMSQKGQQIVNDM
                     RSKSNQITDAFSTMSGPMHSHGVNAMQGLANGIYAGSGAALAAAQSIAARITATIQSA
                     LDIHSPSRVMRDEVGRLIPQGIAVGIDADRKVIDSSMQKLKESMTINATPEIASGFGG
                     GVAGIANQTTNNSNNSFTLNVKVDESDGNSREKYQRLFREFSWYIQQQQGRLGDVK"
     gene            12032..>12584
                     /locus_tag="ACF4ZO_001663"
     CDS             12032..>12584
                     /locus_tag="ACF4ZO_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="distal tail protein Dit"
                     /protein_id="HFD5487180.1"
                     /translation="MTAFIKFDGKKSSDFDLRIINDVEHDSSFYDVDQVKVPGRDGVV
                     LKDNKRLEAIERSYPLRLYSKRRLTEVETDISNWLNVKGWKDLELSWEPDYIYKATHI
                     TPFSIKEVLRNFGRLKINFLIHPIKYLKTGKQEVPLVNGGTLQNPGNVQAKPILKIKG
                     TGNGVLTINGFKTGLENVQGELVI"
BASE COUNT         4216 a         2199 c         2908 g         3261 t
ORIGIN      
        1 agtagagatg tatttctgtg cggatggggg tcaatcagat gccacctcta tgtcttgtaa
       61 tatcgtaaca agagttagag ataacggtag gataaacttc agacttaatc gtgtagctca
      121 ctactaccac agcggagctg acactggtca agtaaaagct atgtcaacct acgctttaga
      181 gttaaaagtt tttatagact ggtgcgttaa aaagtatcag atgcgctata cagaggtatt
      241 tgtggatcct gcctgtaaat ctttgagaga ggagctgcat aagttaggag tatttactct
      301 gggagctccg aacaattcta aagatgtatc tagcaaagcc aaaggcattg aggtcggtat
      361 cgaacgcggc caaaacatta tctcagatgg cgctttttat ctcgttaatc atagtgagga
      421 agagtatgac cattaccact ttttgaaaga gatagggttg tatagtcgtg acgacaatgg
      481 caaacctatt gataaagata accatgccat ggacgagttt agatacagca tcaacgtgtt
      541 tgtgcatcgg tattacaact aaaggagttg cttacatggg agtaatccaa aaaataaaaa
      601 atctttttac aaggagtaaa tacgtgatga caacgcagag tcttacaaat ataactgatc
      661 atcctaagat agctatcagt caaccagagt acgatcgtat aacaaccaat ctaaaatact
      721 ataagagtga ctgggatagt gtcttatatc taaacaccga tggcgagact aaaaaaaggg
      781 gccttaacca cttaccaatt gctcgtacag ctgccaaaaa gattgccagt cttgtcttta
      841 atgagcaggc agagattaag gttgatgatg atgtagctaa caaatttatt agtgagacac
      901 taaaaaacga tcgctttaat aaaaactttg agcgatatct cgagagctgc ctagctttgg
      961 gtggcttagc catgaggcct tatgtggatg gtgacaaagt tagagtggca tttgttcaag
     1021 cgcctgtttt tttgccacta cagagcaaca cgcaggatgt ttcaagcgct gctattgtta
     1081 ttaagtccgt taagacaatc aacggcaaag aggtctatta taccttgata gagttccacg
     1141 aatggcgcag ctctgatgat tatgttatct caaatgagct atatcgctcg gatgataacg
     1201 ccaaagtagg tagccgagta ccgttatctg aggtatacga ggacttaaaa gacgaggcta
     1261 aagttacaga tgtgactagg cctatcttta cttatctcaa gacccctgga atgaataaca
     1321 aggatattaa tagccctcta ggcttgtcaa tctttgataa tgctaagaca acgattgact
     1381 ttatcaatat gacctatgac gaatttatgt gggaagttaa gatgggtcaa cgtcgagttg
     1441 ctgtgccaga gagcttgact gctttaactg ttcgtaccgc tgatggcgat gttattccga
     1501 ggcctcgctt cgagcctgat caaaacgttt atatccgtat gggcggcagg gatttagact
     1561 caagcgcaat acaggaccta acaaccccta ttagagctga tgactatatc aaggctatca
     1621 acgagggctt gtcgttgttt gaaatgcaaa taggcgtatc cgatgggtta tttagttttg
     1681 atggcaaaag catgaagact gcaacagaaa tcgtctctga aaactcagac acctaccaaa
     1741 tgcgtaacag tattgttact ttagtagagc aatcgctaaa agagttagtt atctctattt
     1801 ttgagattgc taaagcttat gatttgtacc aaagcgaagt tccaagcatg gataacatca
     1861 gcataagtct tgatgacggt gtttttacag atcgagacgc tgagttagac tactggataa
     1921 aagttgttaa tgctggcttt ggcactcgtg agatggccat ccaaaaagtg ctaaacgtga
     1981 cagaggaaaa agcccaagaa atagctgcag aaattaatac tggaatcgtt gacgaaatca
     2041 atcaacagcg cactgataca catttatacg gagagtgatt agatgaaaaa gaagcctatt
     2101 aagttaaatg acgaacagct tcttttggaa gctagtcagt tatctgatat gtatcatcag
     2161 ctgactcttg atttatttga tcaagtgatt gagaggataa aagccagagg ctcagcgagc
     2221 ttagccgata atccttatct ttggcaagct aataagttac atgacgttgg actgcttaat
     2281 gcagataaca tcaagcttat tgcaaagtat tctggcattg cggaagctca acttcgctat
     2341 attatcaaga atgaaggatt taaaatttat aaaaacacgt ctgagcagct agaagaggct
     2401 ctaggtagag agtctggggt aaacagtact atccaagacg acctatctaa ctatgctaga
     2461 caagctattg atgatgtgca taatttgact aacaccacct tgccatttag tgttatagga
     2521 gcttatcaag ggataatcca agacgctgtt gctggtgtgg tgacaggctt aaaaacgcct
     2581 gaccaagcta tcaatcaaac tgtgattaaa tggtttaaaa aggggtttta tggttttaca
     2641 gataaagctg ggagaaagtg gagagcagac tcttatgctc gtaccgttat caatactacg
     2701 acttggcgag tctttaacga agccaaagaa gcccctgcta gggagtttgg cattgatacc
     2761 ttctattact caaaaaaagc tacagctaga gagatgtgtg cacctttgca acatcaaatt
     2821 gtcactactg gcgaagcgag agaagaagga gggataaaaa tcttagcttt atctgattac
     2881 gggcatggtg agcctgatgg atgcttggga atcaactgca agcacactaa aacgccgttt
     2941 gtcgtcggtg tgaatagtaa gccagaattg ccagagcatc taaaaaatat cactcctgca
     3001 caagctaaag ctaatgcgaa tgcgcaagct aagcagaggg caatcgagag atcaatacgt
     3061 aagagtaaag agttactgca cgttgcgaag caattgggtg ataaagagtt gattaggcaa
     3121 tatcaatcgg atgttagaag taaacaagat gcactcaatt atctgataaa caacaatgcc
     3181 tttttacatc gcaatcaagc cagagaaaag cgttacaata atccttatac caaaactcaa
     3241 agtgaagtcg aagttagaaa agaaaaagct aaattggata aacgtaggga tgttgaaagt
     3301 gctataatag gagtagaagc tagtgaaggg ataccgctaa aaataacaaa gcatttagcc
     3361 gaaagggcgg tactgagaaa tatagcgcct attgatattg tcgattctat aaaagaaccg
     3421 ttgaagatag ctcctattaa gtacgataac cttgatagac cttcccagaa atacattggt
     3481 aagtgtgtct cgacagtaat aaacccgata gacggaaata ttgttacagt tcatgctact
     3541 agcacgagaa tccgcaaaaa atatggagga aattgatgaa attaaaaagt attttaaatg
     3601 atagtcaaat cgattttgtc aaaaatgaac ttccgggatt acctgtggat atagatgtta
     3661 attccgaaaa gtatgatgtt ttttgtgaag gtatagagac ttactaccag acagaaagct
     3721 ttgatgaaaa gtacaatata acagctaaag ggaaactagc tgagagtatt attgatttac
     3781 tgactgataa aggttattgg tgactagtac accaaactac gacttattaa atctagagca
     3841 tttagctaaa agctaggtgc ttttttgtac ttaaaaaata ggagggaaca tgaataaacg
     3901 cattaagaaa aaacgtaaac tagaaacagc agttgtgatg cttgttgcag aaaatgccat
     3961 gcaggttgaa gcaattaaaa atcaaaacaa acaaatcatg gagctaaaat caatcgttca
     4021 acgaaacgct ctggcaacaa acgaagagtt agcgactgtt aaagctgcta ctttagataa
     4081 ccaatcagtt atcaaggcaa ttggtgacac ggttgactat attaagaaaa actacaaacg
     4141 gaagtggggg aaataaagtt taaccgtgtc gaattcgacc cctttagaaa tcaaagtcgt
     4201 agcaatacgg ctttttatta tgcctttatc cgcaggcgtt aaagaacgga aatcagcgac
     4261 ctatcgcatt tataggaggg aatgcacatg gaaaatgtga caaacgaaaa tgtcgaccaa
     4321 gagactactg acttggaaaa taatcaacaa gaagataaag catttacaca agatgatctc
     4381 aaccgagtgg gaactaaaga gcattctaaa ggctataaca aagcagttaa agacttgggt
     4441 tttgatgatg tagagtctgc caaggatgca ctaaaagcct tccaagagtg gcaagagtca
     4501 caaagaagcg agtcagaaaa acaaacagaa atcttgaatg ctaaagacaa agagcttgag
     4561 gaagctcggg caaacaataa ggctcttaat gcaaagctag cagcaatgtc tttaggtgtg
     4621 aacgctgaat ctattgatga tgtgattgca ctatctgagc gtcttgtcac tgacgagaca
     4681 agcatagagg atgcaatcaa aacggttttg ggtaagtatc ctcactttgg ccaaacaaag
     4741 gataaagctc ccaaaatcac agtggcaggc aacccgtctg ctgataacgg acaaggttcg
     4801 gtgtctaagg aagactttgc aaagatgtct taccaagaaa aactggacct aaaactaaaa
     4861 aataagaatc tttatgacca attgaaagga aattaaaaaa tggcagtagg aacaactaaa
     4921 atggcacaaa tgctagaccc tgaggttcta gcggatatga ttgacgcaga ggtagggaaa
     4981 gcgattcgct ttgctcctct tgctgaagta gatacaactt tagaaggaca accaggtaca
     5041 actttaacag tgcctaaatg ggattacatt ggtgacgcag aagatgttgc cgagggtgaa
     5101 gctatcccaa tgactcaact tggcttcaaa aagactacta tgaccattaa aaaagccgga
     5161 aaaggtgtag aaatcactga cgaagctatc ttatctgggt atggggatcc tgtaggtcag
     5221 gcagcaaagc aaatcgttga ggctattgac cacaaagtcg atgcagacgt gcttgacgcg
     5281 ttaagtaaat cgactcaaac tgtggaagct actgctacgg ttgatggtgt atctaaagcg
     5341 ctagatattt ttaatgacga agatgacgca gagacagtca ttgtcatgaa tccggcggat
     5401 gcctctaccc tacgtttaga tgccgcgaag gagtggttag gtgctaccga ggttggagca
     5461 aatcgtgttg tctctggtgt ttatggtgaa gttttagggg tacaaattgt gcgttctcgc
     5521 aaatgcccta aaggaactgc ctacatggtt cgcaaaggtg cactacgtat catgcttaaa
     5581 cgtaacacaa tggttgaaac agaccgagat atcacaaaag cgattaatca aatcgtagct
     5641 aataagcatt atggtgttta tctttataag gcagaaaaag ccgtcaaaat tacacttaaa
     5701 gatgccgcaa aaaagtagct aaggctaagg ctgccaagag agaggaagat gacgctctcg
     5761 agtcttagcc gatggaggtg gttattatcg cttttttaac gcaaaaagaa tttgaagatt
     5821 tgggttttga cgaggtagaa tattttgaaa aaatggaaaa acgtgctagc cacgctgtca
     5881 atctttactg tcgtaatcgc tatgattaca aagatttaaa aaaagaaata gccctagtgc
     5941 aaaaggctgt aaagcgggca atcgcttatc agatagcata tttaaatgac tcaggagtaa
     6001 tgacagcaga ggataaacaa tcctttgctg gaatatctct aggacggaca agtattagct
     6061 acactgtcgg gcatggccaa ggcagccaac aaaaaactct ggcagacagg tttaatctct
     6121 gtctagatgc agagaatgag ttactagctg ttgggttggg atatacgggt attagctatg
     6181 atcgataaaa gactgcttat tgacgaactg caggtaaaac ttgtcaaaga taaaggtgat
     6241 tatggagggt ttgtctatga cgaacctttt acactctctc cagttaggtt tgaccgtaat
     6301 cttgcaaccg caggtaaaga taatgcaagg caagagacta aaccgtcggt tatctttatt
     6361 tatcctaaat actgtaagac agtagccgat aggtcatggg ttgatgctgt tgtcattgat
     6421 ggtgatactg agtacaccgt tgataaagtg ataccagtct accacccact aacaaacaaa
     6481 attttttgtt ttgaagtgga ggttatctaa tggctaaggt agtggtagag ttgggaggca
     6541 tcaagcgtaa agtatctccg caagcattag ctaaaggaaa gctcatcatg aacaatcaag
     6601 tcatgatgtc catgaaccct tatgttcctt acagagacgg agctttgaga ggaagctcga
     6661 gagctaacag tgtaggtgta acgtggagcg gaccacacgc cagagcccag ttttatggtg
     6721 gtgcttacaa caagtacaag tcctttaaat ttaaaaagta cacaacacca ggtacaggca
     6781 aacgttggga taaacgtgcg ttagctaatg caacaattgt caaggattgg gaaaaatcct
     6841 tactgagagg aatgggattt aaatgacaaa tgactttgca actgttttga ggcaatttgt
     6901 cgaaggatta gacttaggca taaagcctag acttgactat ctaacaagac aagaagacct
     6961 agccatttat ccaatgccag gaggtaaggt aaataacgag tacatggacg gtactcgaga
     7021 gataagcctg ccttttgaga ttgcaatcaa aactaaaaat caggagttag caagcactgt
     7081 gatgtggact attaacagtg ctttgtctaa ctttgactta aaattaccaa gtcttaatca
     7141 ttcgtacaca tttattagcc ttgatgtcga aaagccgttt ttaaatgact taagcgatca
     7201 aggtttttat atttatgtgc tggatattac agcacaccta gaaatagaag ggaaaaacta
     7261 atggcaagac aaaagaacgc cttacgcggg cattttatcg caccttataa cgctggagta
     7321 gagcctgaag caaaaggttc tgaatggatg gaaatcgcaa aatggattaa ggacatttct
     7381 gatgataccg acgaaaaaac cgaagatgaa gcgtattatg acggtgacgg aaccgaagaa
     7441 acaactgtag ttggtgtcaa aggcgcatat acgtttgaag ggacttatga cccggaagat
     7501 aaggcgcaaa agcacattgc ggatatgaag tataaaacag gagagggccg aaaggtttgg
     7561 cacaaggttg ttgcatcaga taacaaaaaa caatggatag gcctgtctac ggtttccgag
     7621 attattgcag gttctggtgc tgcagccgat tttgaagcct ttagttgtaa gattacttat
     7681 aactcattgc caaaagaaag tgtcccaagt gaggttttat aaggttgggc taactgctca
     7741 accttatatt ttttaaggag gaattatgtc tgaaattgta gttgacctaa agcgcacggg
     7801 ttttccggtc aaaattggtc aggtagagct ttggtttgat acaagtcaag agcgattgat
     7861 tgagtttttt gatattgaga ccgaagtaaa acgtcgcctc aatgaatatg aaaaacaggt
     7921 tatcgaagcc aacttagaca acgaaattga agataaagga gttacgaaag atgttgccca
     7981 aagtgcttta gatttggaag ctaaatactt agaaatcaat tatgatctac tattcggaga
     8041 aggtacattt gcacagctct acgcggagta tcccgacaaa gaagcactcg agaatactct
     8101 ggaaattgtt tgcagggaaa ttgaggtcaa actcaaagag ttagctatcg aaagagaaaa
     8161 aatcgttaag cagaaaatga aaaagtacaa aaaggggtag cctatgaaac taaacgatcc
     8221 attagtagag tcgtttgagt ttagaggtga aatttactcc attaatttga gttttaacaa
     8281 ggttttagat gtatttgacg ttattgatga tgacttttta aatgaggcgg aaaagtgttt
     8341 tttgtgcctt gatattttgc tagatagaac agatttacct ttttcctatg ctgtggacct
     8401 ttggattcat atcaaaaaaa attatattga tacgaaaaag tctgagaagc ctcagcttga
     8461 catcaaaggg aatccgatgc ctgtagtaaa agaaaaagag gataacgaaa aagtcattga
     8521 tttaagattg gacgctgagt ttatctatgc gagttttagg caagcctacc aaatcaatct
     8581 tttaaaagag caaaacagat tgtcttggat tgaattcaag gctcttttaa atgctcttcc
     8641 agacgatact gtcatgcagc gtatcatagc cattagacag tgggaagatg atggtgaagg
     8701 cagtaaaaaa tacagagata acatgcgtaa gctaaaggct aagtacagtt tagatgaagg
     8761 agaggaagag gacgatggca gctgatggta aggtaacgat acttattgac gttgatggta
     8821 agcaggtaaa ggtactcaat agtgagttag ataaagttgc caagcacggt gacaaaggca
     8881 gctcctctct taaaaaattt gcggttggtg caggagtctt taaattagct tcggctgcag
     8941 ttgatttggt tagtcaatct cttggcaagg ctatcacaag atttgacacg cttgaaaaat
     9001 atccaagggt catgaaagct atggggcata gcgctgagga tgttgctaga tcaactgata
     9061 agttagcgaa cggaattgat ggactaccaa caactttaga cgaggttgtc ggaaccgctc
     9121 aacgtttgac ctctattact aaggatatca ataaatcaac taatctcaca ctagcattaa
     9181 ataatgcctt tttagcttca ggagcttcat cagaggctgc aagccgaggg ctggagcaat
     9241 atgcccaaat gctatcagct ggtaaggttg atatgcaagc ttggaaaacc ctccaagaaa
     9301 caatgcctta tgccttacaa caaactgcgg aagcttttgg atttgcaggg gcatcggctc
     9361 aaaaggattt ttatgaggcg ttaaaaaacg ggcaaataac atttgaccaa ttttctaata
     9421 agttgattga gttaaatgat ggtgtcggcg gttttgcaga actagccaaa gaaaatagta
     9481 aagggattga aacctctttt aacaacatca agaacgctat tgcaaaaggt gtggccaata
     9541 gcattaaggc tttggatgat ttgtctaagg ctgcaacagg taagggcata gctgatcatt
     9601 ttgatagttt gaaagttgtt atcaatgcct cttttagcgc catcaatgca agtattaaag
     9661 ctagtacacc gctatttaaa cttttgttta gtgttattgg tgctggaata tcagtcgtca
     9721 aagctctgtc gcctgcctta gttggtgtag catctggtct agctgccatg agggcagtta
     9781 atgagactat aacaatgatt aaagcgctaa atagagcttg ggttatggca tctgcatcaa
     9841 tgagtattgg agcaacaacc attaagactg tgactgcggt acaagcggta agtaccacga
     9901 tgactaaagc agatatggtt gcaagactat ctcagttagg tgtcttaaaa gccagtaccg
     9961 tgatttatgg tgttatgaca ggcgctatca gtttatctac tgctgcaacc atagccagta
    10021 ctgctgcggt aactgcgtta aaagcagcac ttgtagcctt aacaggtccc gttggttggg
    10081 tagttggagc tatcggtgct ttagttgctg tcggagtaag cttatggtca tggctaacta
    10141 aagagtcaga cgagaccaaa aagctgaaaa aagagcagga ggggctagtc gaaagcaaca
    10201 aacagctaag agattctgtc cgtgagggcg tgcaagagcg taagaagggc cttgagtccg
    10261 tcaaagagag cactgcagct catcaaaaat tagctgacga aatcattaag ttagccgcca
    10321 aagaaaacaa aactgcaggc gaaaaacaaa acttaaaaaa taagattgat cagcttaatg
    10381 ggtctattga tggcttaaac ttggcctatg acaaaaactc caattctctt tctcacaatg
    10441 cagatcaaat taagtcacgc attagtgcca tggaagcaga aagcacatgg caaacagcac
    10501 aacaaaatct gttaaatatt gaacagaaac gtagcgaggt tagcaaaaag ctagctgaaa
    10561 atgctgattt gcgtaaaaag tggaatgaag aagctaacgt ctccgattcc gtccgaaaag
    10621 aaaagattgc agaactcaca gaagaagaag ctaaacttaa aaatatgcag actcaactgc
    10681 aggaggagta taacaagaca tcagctactc aacaagctgc tgcagacgct atggctgccg
    10741 ctgaagaatc aggatcagca agacaggtta tagcgtacga aaatatgtca gaagctcaac
    10801 gaactgccat agacaatatg cgcactaagt actctgaact tttagagaca acgacatcta
    10861 tttttgatgc tatagaacaa aagacggcat tatcagtaga tcaaatgaat accaaccttg
    10921 aaaaaaatag agctgctact gaacagtggg ctactaattt ggagattttg gctcagcgtg
    10981 gtgtggatca aggtattttg gagcaactaa gacgcatggg tcctgaagga gccacacaga
    11041 cgcaagtttt tgtggatgca acagatgccg agctagcacc cttgcaggaa aactttagag
    11101 cagccacaga aactgctaaa aatgcaatgg ggagcgtttt agactcagca ggtgtggaaa
    11161 tgccagaaaa agttaaaggg atggtcacta atgtttctac gggattacag gcggaactgc
    11221 aagctgctaa ctttgctcaa cttggccaag aaatccctaa tggggtttct caaggtataa
    11281 gtcaaggggc aggtaaagca agtgacgcaa gtgtcaaaat gggtcaagaa gttaaacgct
    11341 cttttcaagg agagttgggt atccactcgc catcgcgagt atttactgag tacggtggcc
    11401 atattactga tggcttgagt aatggtgtga caaatggaac gtcaaaagtt atgcaaacca
    11461 tgcagagctt ggctcaacag atgtctcaaa aaggacagca gattgttaat gacatgcgta
    11521 gcaagtcgaa ccaaatcaca gatgctttta gcacgatgag tggtccaatg cactctcatg
    11581 gtgttaatgc catgcaaggt ttggccaatg gtatttatgc agggtcgggg gcagctttag
    11641 cggcagctca aagcattgcg gcacgtatca ccgcaacaat tcaaagtgcc ttagatatcc
    11701 actcgccatc tcgtgttatg agggatgagg ttggacgtct tatccctcag ggtatcgctg
    11761 taggtattga tgcggataga aaagtcattg actcatctat gcaaaagcta aaagagtcaa
    11821 tgacgattaa tgcgactcca gaaatagcct ctggatttgg cggaggagtt gcggggattg
    11881 ctaatcagac cacaaataac tcaaataaca gttttaccct taatgtcaag gttgatgaat
    11941 ccgacggtaa tagccgcgag aaatatcaac gcttattcag agaatttagc tggtatattc
    12001 aacaacaaca aggaaggtta ggtgatgtta aatgacagct tttatcaagt ttgatggtaa
    12061 aaaatcttca gattttgatt tgagaattat taatgacgtt gagcatgact cgtcctttta
    12121 cgatgttgat caagttaagg tacctggtcg tgatggtgtg gttttaaagg acaataaaag
    12181 gcttgaggct attgaacggt cttacccttt acgtctatac agcaaaagac gactcaccga
    12241 agtagaaact gacataagca attggctgaa tgtaaaaggt tggaaagact tagagttgtc
    12301 atgggagcct gattatatct ataaagcaac acatatcacc ccttttagca taaaggaggt
    12361 tttaaggaat ttcggcagac tgaaaatcaa cttcttaatc caccctatca aatatttaaa
    12421 aacaggtaag caagaggtgc ctctcgttaa tggcggtact ctacaaaatc ccggcaatgt
    12481 tcaagctaaa cctatcctaa aaatcaaagg cacaggcaat ggtgttttaa ccattaatgg
    12541 ctttaagaca gggctggaaa atgtgcaagg agaactcgtc atag
//
LOCUS       DAXMQE010000047        11703 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.047, whole genome shotgun sequence.
ACCESSION   DAXMQE010000047 DAXMQE010000000
VERSION     DAXMQE010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11703)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11703)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11703
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.047"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            286..390
                     /locus_tag="ACF4ZO_001664"
                     /pseudo
     CDS             286..390
                     /locus_tag="ACF4ZO_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014293804.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(473..1456)
                     /locus_tag="ACF4ZO_001665"
     CDS             complement(473..1456)
                     /locus_tag="ACF4ZO_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFD5487181.1"
                     /translation="MVIIAVVIFFGVILGILIVEYGQKRSFSSWLVEKMFAYRKYKLS
                     KKVDNYKGVETQRNRNIPYHLDNPEEIVGFSTQEYDVNGMQVFIINDQKQSHQHVIYY
                     LYGSVYLRRPEKLHFKTVKHLIQLTNAKVVFPNFPKVPYATYQDVYPKLVEAYQQFCL
                     SNGPSQVSVIGDSSGGGMALAFAKYIRDTKTAPQPKQLILISPWLDVSFKNQAYKDFE
                     AEEAYLDARRLRDIGELWAGCQGNMQLPYVSPLYGDYEDLPEITTFVGTKEIFYPDIM
                     SLHDQLTRQRIANQLIIAEKMIHAYVIFPIREAKQARKQIAELVLKTVEHT"
     gene            complement(1487..2737)
                     /gene="dltD"
                     /locus_tag="ACF4ZO_001666"
     CDS             complement(1487..2737)
                     /gene="dltD"
                     /locus_tag="ACF4ZO_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070394 - lipoteichoic acid metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HFD5487182.1"
                     /translation="MLKRLWLILGPLLIAFVLVVITIFSFPTQLDHSIAQEKANAVAI
                     TDSSFKNGLIKRQALSDETCRFVPFFGSSEWSRMDSMHPSVLAERYKRSYRPFLIGKR
                     GSASLSHYYGMQQITNEMQKKKAIFVVSPQWFTAQGINPSAVQMYLSNTQVIEFLLKA
                     RTDKESQFAAKRLLELNPGVSKSNLLKKVSKGKSLSRLDRAILKCQHQVALREESLFS
                     FLGKSTNYEKRILPRVKGLPKVFSYKQLNALATKRGQLATTNNRFGIKNTFYRKRIAP
                     KYNLYKNFQVNYSYLASPEYNDFQLLLSEFAKRKTDVLFVITPVNKAWADYTGLNQDK
                     YQAAVRKIKFQLKSQGFHRIADFSKDGGESYFMQDTIHLGWNGWLAFDKKVQPFLETK
                     QPVPNYKMNPYFYSKIWANRKDLQ"
     gene            complement(2730..2969)
                     /gene="dltC"
                     /locus_tag="ACF4ZO_001667"
     CDS             complement(2730..2969)
                     /gene="dltC"
                     /locus_tag="ACF4ZO_001667"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0036370 - D-alanyl carrier activity
                     [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HFD5487183.1"
                     /translation="MSIEETVIELFDRLFMEDVSEMMDEDLFDAGVLDSLGTVELIVE
                     LESTFNIKVPISEFGRDDWNTVTKIVQGVEELQHA"
     gene            complement(2987..4243)
                     /gene="dltB"
                     /locus_tag="ACF4ZO_001668"
     CDS             complement(2987..4243)
                     /gene="dltB"
                     /locus_tag="ACF4ZO_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0070395 - lipoteichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HFD5487184.1"
                     /translation="MMMFFSHIPYMEPYGNPIYFVYLILAFLPVIIGIFKQKRLSTYE
                     TLVSLVFILFMFGGDHYQQLVAFLFYLLWQIISVFAYQKYREKANSAGVFYLAIAMAL
                     FPLIWVKVAPLTGPSSQTLFSFLGISYLTFKSIGMIIEMRDGTLQEVRLPDFIRFMIF
                     FPTFSSGPIDRFRRFQEDYHKLPERDDYFAMLNKAVMYLMLGFLYKHIISYCLGGILL
                     PLLENKALMVGGYFNKETILVMYVYGLNLFFDFAGYSMFAIGISYLLGIRTPENFNMP
                     FLSASLKDFWNRWHMSLSFWFRDYVFMRLVHLLIKHKTFKNRNVTSGVAYLVNMLVMG
                     FWHGLTWYYIAYGLFHGIGLIINDAWIRKKKEINRHRKKKGLSPLFQSRAFHVLCIVV
                     TFHVVMFSLLLFSGFLNDLWFNRPLH"
     gene            complement(4240..5778)
                     /gene="dltA"
                     /locus_tag="ACF4ZO_001669"
     CDS             complement(4240..5778)
                     /gene="dltA"
                     /locus_tag="ACF4ZO_001669"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047473 - D-alanine [D-alanyl carrier
                     protein] ligase activity [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HFD5487185.1"
                     /translation="MIKDMIDSIEQFAQTQADFPVYDCLGERRTYGQLKRDSDSIAAF
                     IDSLALLAKSPVLVFGAQTYDMLATFVALTKSGHAYIPVDVHSAPERILAIIEIAKPS
                     LIIAIEEFPLTIEGISLVSLSEIESAKLAEMPYERTHSVKGDDNYYIIFTSGTTGQPK
                     GVQISHDNLLSFTNWMIEDAAFDVPKQPQMLAQPPYSFDLSVMYWAPTLALGGTLFAL
                     PKELVADFKQLFTTIAQLPVGIWTSTPSFADMAMLSDDFCQAKMPALTHFYFDGEELT
                     VSTARKLFERFPSAKIINAYGPTEATVALSAIEITREMVDNYTRLPIGYPKPDSPTYI
                     IDEDGKELSSGEQGEIIVTGPAVSKGYLNNPEKTAEAFFTFKGQPAYHTGDIGSLTED
                     NILLYGGRLDFQIKYAGYRIELEDVSQQLNQSPMVASAVAVPRYNKEHKVQNLLAYIV
                     VKDGVKERFDRELELTKAIKASVKDHMMSYMMPSKFLYRDSLPLTPNGKIDIKTLINE
                     VNNR"
     gene            complement(5790..5933)
                     /locus_tag="ACF4ZO_001670"
     CDS             complement(5790..5933)
                     /locus_tag="ACF4ZO_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HFD5487186.1"
                     /translation="MIKNKSRMRGIAVFIGKTILFYLILMLLVYFFGYLGHGQSNFIY
                     NEF"
     gene            complement(6196..8187)
                     /gene="uvrB"
                     /locus_tag="ACF4ZO_001671"
     CDS             complement(6196..8187)
                     /gene="uvrB"
                     /locus_tag="ACF4ZO_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002261961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HFD5487187.1"
                     /translation="MIDKRDDKPFKLKSKYKPSGDQPQAIESLVDNIEGGEKAQILLG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPDNAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVVASVSCIYGLGSPKEYA
                     DSAVSLRPGQEISRDTLLNQLVDIQFERNDIDFQRGCFRVRGDVVEVFPASRDEHAFR
                     VEFFGDEIDRICEIESLTGKTIGEVDHLVLFPATHFVTNDEHMEQSIAKIQAELAEQL
                     QLFESEGKLLEAQRLRQRTEYDIEMLREMGYTSGVENYSRHMDGRLPGEPPYTLLDFF
                     PEDFLIMIDESHMTMGQIKGMYNGDQARKQMLVDYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGEYEMSQTNTIIEQIIRPTGLLDPEIDVRPSMGQMDDLLGEINQRVARD
                     ERTFITTLTKKMAEDLTDYLKEMGVKVKYMHSDIKTLERTEIIRDLRLGVFDVLIGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNVDGHVIMYADKMTDSMQ
                     RAIDETARRREIQIAYNKAHGIVPQTIKKDIRGLISISKTSHNDISKEEMDYESMSRG
                     ERKEAINALQKQMQEAAELLDFELAAQMRDLILELKLMD"
     gene            8379..10553
                     /locus_tag="ACF4ZO_001672"
     CDS             8379..10553
                     /locus_tag="ACF4ZO_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HFD5487188.1"
                     /translation="MTHKIKVLLLAIMSIFLTCNIASAETIAIVSDTAYAPFEFKDSD
                     QIYKGIDVDIINEVAKRQSWDFSMSFPGFDAAVNAVQSGQASALMAGTTITNARKKVF
                     HFSEPYYDTKIVIATRKANTIKKYSDLKGKTVGVKNGTAAQAFLNNYKKKYDYTVKTF
                     DTGDLMYNSLSAGSIAAVMDDEAVIQYAISQNQDIAINMKGEPIGSFGFAVKKGSGYD
                     YLVNDFNTALKAMKADGTYQAIMTKWLGTDDKATTSQATGNPSAKATPIKDSYKIVSD
                     SSFAPFEFQNGKGKYVGIDIELIKAIAKQQGFKIEIANPGFDAALNAVQSSQADGVIA
                     GATITDARKAIFDFSDPYYTSNIILAVKAGKNIKNYEDLDRKTVGAKNGTSSYSWLKE
                     NAPKYGYNVKAFDDGSSMYDSLNSGSVDAIMDDEAVLKYAISQGRRFETPLEGISTGE
                     VGFAVKKGTNPELIEMFNNGLAALKKSGQYDDIIDKYLDSKKAATPSEKSADESTISG
                     LLSNNYKQLLAGLGTTLSLTLISFAIAIIIGIIFGMMAVSPTKSLRLISTVFVDVVRG
                     IPLMIVAAFIFWGVPNLIESMTGHQSPINDFLAATIALSLNGGAYIAEIVRGGIEAVP
                     AGQMEASRSLGLSYGTTMRKVILPQAVKLMLPNFINQFVISLKDTTIVSAIGLVELFQ
                     TGKIIIARNYQSFRMYAILAIIYLIMITLLTRLAKRLEKRLN"
     gene            10553..11293
                     /locus_tag="ACF4ZO_001673"
     CDS             10553..11293
                     /locus_tag="ACF4ZO_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003107174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HFD5487189.1"
                     /translation="MTELKIDVQGLHKSYGQNEVLKGIDAKFYEGDVVCIIGPSGSGK
                     STFLRTLNLLETITSGKVMVDGFELSDPKTNIDKARENIGMVFQHFNLFPHMTVLENI
                     IFAPVELGKESKEVAKKHGMALLEKVGLSDKADAFPGSLSGGQKQRVAIARSLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKDLAEQGMTMLIVTHEMGFARQVANRVIFTDGGQF
                     LEDGTPEEIFDHPKHPRLIEFLDKVLNV"
     gene            complement(11441..11593)
                     /locus_tag="ACF4ZO_001674"
     CDS             complement(11441..11593)
                     /locus_tag="ACF4ZO_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5487190.1"
                     /translation="MTEKNGATFLMAVGFFLIAISPMVGNKYLHIVTGLALTGLGYYL
                     TKHKRP"
BASE COUNT         3744 a         2315 c         2041 g         3603 t
ORIGIN      
        1 cctctggaac tctagttatc gatgaactcg ttgcacttga cttgacaact tgcgagagca
       61 tatcagtagt ttttctgcta attgaaaaca gggtatttac tatcacacaa gtctgtcctt
      121 tctttttttt ctacaacttt atttcgtcag cgtaaataaa acaaaagctc tataatctct
      181 tgaatgggta aatccactgt agagattata gagctttttg aatatcaaaa aagtcccata
      241 agatttataa tgaaaagcaa ccaaactctc attagaaaga ctcttatgga acatatcaat
      301 cataccttac aacacatcgg aattaaagac aaaaatatca ctctaaacaa tgttttgaag
      361 gatgaatctc ctactgagct cgttactact tatcagaaag gtagatagga aatcctgatg
      421 aagagtgtgt ccaagggatt atcaattagg tcttagatta caaaatagta attcaggtat
      481 gctctactgt tttcaacact agttctgcaa tttgttttcg agcttgctta gcttctctta
      541 ttggaaaaat aacatacgca tgaatcattt tttctgcaat aatcagctga ttagcaattc
      601 gttgtcttgt taattgatca tgtaaagaca taatgtctgg gtaaaaaatc tcttttgtcc
      661 caacaaaggt cgttatttca ggcaaatcct cataatcacc atacaaagga ctgacataag
      721 gaagttgcat attaccttga caacctgccc atagttcacc tatatcacga agacgacgag
      781 catctaggta agcttcttct gcttcaaaat ccttgtaggc ttgattttta aaactaacat
      841 ctaaccaagg agatataaga attaattgct ttggctgggg tgctgtttta gtatctcgta
      901 tatacttagc aaacgccaaa gccatacccc caccagaaga atcaccaatg acactaactt
      961 gactcggtcc attagacaag caaaattgct ggtaagcttc aactaattta ggatagacat
     1021 cttgataagt agcatacggt actttaggaa agttaggaaa aacaaccttg gcattagtca
     1081 gctgtataag atgcttaacc gtcttaaaat gaagtttttc gggtcgtcgt aaatagacac
     1141 tgccataaag ataataaata acatgctgat gactttgctt ttgatcatta ataataaaaa
     1201 cttgcatccc gttcacatcg tattcttgag ttgaaaaacc tactatctct tcaggattat
     1261 ctagatgata agggatatta cgattacgct gcgtctcaac ccccttataa ttatcaactt
     1321 ttttagataa cttatacttt ctataagcaa acattttctc aaccaaccaa cttgaaaagg
     1381 agcgcttttg accatattca actatcaaaa tacctagtat cactccaaaa aaaatcacca
     1441 cagcaataat gaccacttat tatcctcgtt ttctaatatt attttactat tgcaagtctt
     1501 tcctatttgc ccaaatttta ctataaaaat aagggttcat tttatagttg ggcactggct
     1561 gcttcgtttc tagaaatggt tgcactttct tatcaaaagc taaccagcca ttccaaccga
     1621 gatggatggt atcttgcata aagtaggact caccaccatc ttttgagaag tcagcaatgc
     1681 gatgaaatcc ttgtgacttt aactggaatt ttattttacg aactgccgct tgatacttat
     1741 cttgatttaa gccggtataa tccgcccaag ctttattaac aggagttata acaaagagta
     1801 catctgtttt tcgtttagca aattctgata acaaaagctg aaaatcattg tattctggtg
     1861 acgccaggta actataatta acttggaaat tcttataaag attgtattta ggtgctattc
     1921 gtttacgata aaatgtattt ttaatcccaa aacggttgtt ggttgttgct aattggcctc
     1981 tcttagttgc taacgcattc aattgtttat acgaaaatac tttaggtaat cccttaacgc
     2041 gaggcaaaat tcttttttca tagttagtag atttgcctaa aaaactaaaa agggactctt
     2101 ctctcaatgc tacttgatgt tgacatttca aaatagctct gtctaaccga ctaagagact
     2161 tacccttact tacttttttc aataagtttg atttagacac accagggtta agctcaagca
     2221 aacgctttgc tgcaaactgt gattctttat cagttctagc ttttagtaaa aattcaatca
     2281 cttgagtgtt agacaagtac atctgaaccg cactaggatt aatcccttga gcagtaaacc
     2341 attgaggaga tactacaaag atggcttttt tcttttgcat ttcattggta atttgttgca
     2401 taccataata atgcgacaaa gatgctgatc ctctcttacc aattaaaaat ggtctatagc
     2461 tccgcttgta gcgctctgca agcaccgaag ggtgcatact atccattcga ctccattcgc
     2521 tagaaccaaa aaaaggcaca aaacgacaag tctcatctga taaagcttgt cttttaatca
     2581 aaccattttt aaaagaacta tctgtgatcg caacggcatt tgctttttcc tgagctatgg
     2641 aatgatcaag ttgtgtagga aaactaaaaa tagtaatcac tactaaaaca aaggcaataa
     2701 gaagaggacc tagaattaac cagagtctct taagcatgtt gcaattcctc tacaccttga
     2761 acaatcttag ttactgtgtt ccaatcatca cgaccaaatt ctgaaatagg tactttaata
     2821 ttgaacgttg actctaactc aacaatcaat tcgactgtcc caagactatc caacacacct
     2881 gcatcaaaca agtcttcgtc catcatctct gaaacatctt ccataaacaa acggtcaaac
     2941 aattcaatta cagtttcttc aatagacatt tttatacttc cttttattaa tgtagtggtc
     3001 tgttaaacca aaggtcattt aaaaaaccag agaataacag aagtgaaaac atgacaacgt
     3061 ggaaagttac cacgatacat aagacatgga atgccctgct ttgaaagagg ggtgataagc
     3121 cttttttctt acggtgacgg ttgatttctt ttttcttacg aatccaagca tcattaataa
     3181 taagtcctat accatggaaa agcccataag cgatataata ccaggttaag ccatgccaaa
     3241 atcccatgac tagcatatta accagatagg caacacctga agtgacattt cggtttttaa
     3301 aggttttatg cttaatcaat agatgaacca atcgcataaa cacataatct ctaaaccaga
     3361 aggacaaact catgtgccat ctattccaaa aatctttcaa gcttgcagat aagaaaggca
     3421 tattaaagtt ttctggtgtt cgaataccca ataggtagga aataccaatc gcaaacatcg
     3481 aataaccagc aaagtcaaaa aagagattca agccatacac gtacataacc agaatagttt
     3541 ccttattaaa gtagccacca accatcaaag ccttattttc aaggagagga agtaagatgc
     3601 cacccaaaca ataggaaatg atatgcttgt ataggaaacc taacatgaga tacatgactg
     3661 ccttattgag cattgcaaaa taatcatcac gttcaggaag tttatgataa tcttcctgaa
     3721 aacgtctgaa gcgatcaatg gggccacttg agaaagtggg gaagaaaatc atgaagcgaa
     3781 taaaatccgg taaacgaacc tcttggagag tcccgtcacg catctcaata atcattccaa
     3841 tacttttaaa ggtcaaatat gaaatcccta gaaaactaaa gagtgtttga gaagaaggac
     3901 ctgttagggg agcaactttg acccagataa gggggaataa ggccatcgca atagctaagt
     3961 aaaacactcc tgcactatta gctttctcac ggtatttctg gtaagcaaaa acactgatga
     4021 tttgccacaa aagataaaag agaaaagcaa ctaattgttg ataatgatct cctccaaaca
     4081 taaagagaat aaataccaaa ctcaccaagg tttcataagt gcttaagcgc ttttgtttaa
     4141 aaatcccaat gatgactggt aagaaagcca aaataagata gacaaagtaa atggggttac
     4201 cgtaaggttc catgtaggga atgtggctaa aaaacatcat catcggttat tgacctcatt
     4261 aatcaaagtt ttaatatcta tcttaccatt tggagttaat ggtagactgt ctcgataaag
     4321 aaacttagaa ggcatcatat aactcatcat atgatcctta acagaggctt tgatagcttt
     4381 ggttaactcc aattccctat caaaacgctc tttaacccca tctttgacaa cgatataggc
     4441 caagagattt tgaaccttat gttctttatt gtaccttgga acagccacag ccgatgctac
     4501 cattggtgat tgattcaact gttgggaaac atcttctagt tcgatacgat aaccagcata
     4561 tttaatctga aaatccaaac gcccaccata cagcaaaata ttatcttctg tcaatgagcc
     4621 aatgtcccct gtatgataag caggctgtcc tttaaaagta aagaaagctt ctgcggtttt
     4681 ctcaggattg ttgaggtaac cttttgacac agcaggccct gtaacaataa tttcaccctg
     4741 ctcccctgaa gataactcct taccatcttc atcaataata taggtcggag aatctggttt
     4801 ggggtagcca atcggcaagc gggtataatt atccaccatt tctctagtaa tttcaatagc
     4861 ggataaggct acagtcgctt ctgttggtcc ataggcattg ataatcttgg cactcgggaa
     4921 acgttcaaag agttttcgag ccgtagaaac ggttaattct tcgccatcaa aataaaaatg
     4981 cgttaaagct ggcatcttag cctggcaaaa atcatcgcta agcatggcca tatcagcaaa
     5041 tgaaggagtc gatgtccaaa tgccaactgg aagttgcgca atcgttgtaa ataactgttt
     5101 aaagtctgcc accaattctt ttggaagtgc aaataaggtt ccacctaaag ccaaggtagg
     5161 tgcccagtac atgacagaaa ggtcaaagga atagggtggc tgtgccagca tttgtggctg
     5221 tttaggtaca tcaaatgctg catcttcgat catccagttg gtaaagctca aaagattgtc
     5281 atgtgaaatt tgcacccctt ttggttggcc cgttgttcca gaggtgaaaa taatgtaata
     5341 attatcatct cctttaacag aatgtgttcg ctcatagggc atttctgcta attttgctga
     5401 ctcaatctct gatagtgaga caagggaaat cccttcaata gtaagaggga attcctcaat
     5461 agcaatgatt aaactgggct ttgcaatctc aataatcgct aaaatacgtt ctggtgctga
     5521 atgcacatct actgggatat aggcatgacc agatttggtt aaagctacaa aagtagctaa
     5581 catatcataa gtttgcgccc caaaaaccaa aactggagat tttgccagta aagctaagct
     5641 atctataaat gcagcaatgc tatcagaatc tcttttgagt tgtccgtaag tgcggcgttc
     5701 ccctaaacaa tcataaactg ggaaatcagc ctgtgtctga gcaaactgct caatactgtc
     5761 aatcatatcc ttaatcatca gtcaatctcc taaaattcat tataaataaa gttactttga
     5821 ccatgtccta gataaccaaa gaaatagacc agcaacatta aaatcagata aaataaaatt
     5881 gtcttgccaa taaaaacagc aattcctctc attcttgatt tgttttttat catactttac
     5941 cttcttgtat tagtgaaata atgtcctaaa aaattctact cgaaaaaacc taacttgaca
     6001 agctaaaagt catattatta aaaagaaaat ttttttaaag cttaactatt taaacagtta
     6061 aattttatgc ctttttacta aacttactaa gttaatcttt actttaaaaa gttaacttaa
     6121 aattgtccta ataaaaagaa ttatttgact ttaacttata tatgttataa gtataatata
     6181 agctttattc aaaacctagt ccattaattt aagctctaaa atcaagtctc gcatttgagc
     6241 tgccaattcg aaatcaagta attcagctgc ctcttgcatt tgtttttgca gagcattgat
     6301 cgcttctttt cgttctcctc ttgacatact ttcataatcc atctcttctt ttgatatatc
     6361 attgtggctt gttttactta tactaataag gcctctgatg tcttttttta tagtttgtgg
     6421 aacgatgccg tgcgctttgt tatatgctat ttgaatctca cgacgacgag ccgtttcgtc
     6481 aatagctcgc tgcatagaat ctgtcatctt gtccgcatac ataatgacat gaccatctac
     6541 gtttcgagct gctctaccga tggtctgaat caagccgcgt tcattacgga ggaaaccctc
     6601 tttatcagca tccaaaatgg ctacaagact aacttctggc acatcaatcc cttcacgaag
     6661 cagattgatt ccaatcaaga catcaaaaac accaagtcgt aaatcacgaa taatttctgt
     6721 tcgctctaag gttttaatat cactgtgcat atacttgacc ttgacaccca tctcttttag
     6781 ataatcagtc aaatcttctg ccattttttt agttaaggtt gtgatgaacg tccgttcatc
     6841 gcgcgctacg cgctggttaa tttctcccaa caaatcatcc atttgcccca tacttggcct
     6901 tacatcaatt tcaggatcaa gtagcccagt cggacgaata atttgctcaa taattgtatt
     6961 agtctgtgac atttcgtatt caccaggcgt tgctgaaaca tagacaattt ggtgcacatg
     7021 actttcaaat tcctcgcgtc ttaagggacg attatcaaga gctgatggca atcgaaaacc
     7081 atagtcaact agcatttgtt ttctggcttg gtcaccatta tacatgcctt tgatttgtcc
     7141 cattgtcatg tgactttcat caatcataat taaaaaatct tctgggaaga aatctaacaa
     7201 ggtataagga ggttctcctg gtaacctgcc atccatatga cgggaatagt tttcgactcc
     7261 gctagtatag cccatttcac gtaacatttc aatatcatat tccgttcttt ggcgtaatcg
     7321 ctgtgcttct agtagtttac cttcagattc aaataactgt aactgctctg ctaactctgc
     7381 ttgaattttg gctattgatt gctccatatg ctcatcattt gttacaaagt gagtagctgg
     7441 aaataaaacc aaatgatcaa cttctccaat agttttccca gttaaacttt cgatttcaca
     7501 tatacggtca atctcatccc cgaaaaattc cacccgaaaa gcatgttcat ccctggatgc
     7561 tggaaagacc tcaacaacat cgccacgtac acgaaaacag ccgcgttgaa aatcaatatc
     7621 attacgctca aattgaatat ctactaattg atttagcaaa gtgtcacgtg atatctcctg
     7681 acctggacgt agactgactg ctgaatctgc gtactctttt ggcgaaccta gtccataaat
     7741 acaagataca gaagctacca ctatgacatc gttacgctca agtaaagaag aggtggctga
     7801 atggcgaagt ttatcgattt catcattgac tgaactatct ttttcgatat aggtgtcgct
     7861 tgatgggaca tatgcttcag gttggtagta atcataatag gaaacaaaat attccacagc
     7921 attgtctgga aaaaattctt taaattcacc atataattgt cctgctaagg ttttattgtg
     7981 agctatcact aaggtaggtt tatttacttt actaattact tggctcatgg tgtatgtttt
     8041 tcccgttcct gtagcaccta ggagaatctg agctttttct ccgccctcga tattatcaac
     8101 taggctttca atagcttgtg gctgatcacc agacggttta tactttgatt ttagtttaaa
     8161 tggtttatca tcacgtttat caatcatttt ataccctcta atagtctcat ctcttataga
     8221 ctattttaac atagataagc cagaatcacc tccaataagc gtaaaaaaca tgtcatttac
     8281 atgttatgtt ttatgacata taaataacaa atttcttgct taatgttcaa cattttgtta
     8341 taattaacca tattttttag ttttataagg agattagtat gacgcacaaa ataaaagtat
     8401 tgctgcttgc gataatgtct atttttttga catgcaatat tgcaagtgct gaaactattg
     8461 ctattgtttc agatacagct tatgccccat ttgaatttaa agactcagat caaatttaca
     8521 aaggaattga cgttgatatt attaatgaag tagccaaacg tcaatcttgg gatttcagta
     8581 tgagtttccc gggttttgat gcagctgtaa atgctgttca atctggtcaa gcgagtgctc
     8641 taatggccgg tacaaccatt acgaatgctc gtaagaaagt ctttcatttc tcagagccat
     8701 attacgatac caaaattgtc attgcaacac gtaaagccaa taccatcaaa aaatacagtg
     8761 acttaaaagg aaaaacggtc ggtgttaaaa atggaacagc ggctcaagcc tttttgaata
     8821 actataaaaa aaagtatgat tatactgtta aaacatttga cacaggtgat cttatgtata
     8881 acagtttatc tgctggttct attgccgctg ttatggatga tgaggcggtt atccaatacg
     8941 caatcagcca aaaccaagat attgctatta acatgaaagg agagcccatt ggaagctttg
     9001 ggtttgctgt caaaaaggga agcggatatg attatctagt taatgatttc aatacagctc
     9061 ttaaagctat gaaagctgat ggtacctacc aagctatcat gaccaagtgg ttaggcacag
     9121 atgataaagc taccaccagc caggcaacgg gaaatccatc tgccaaagct acacctataa
     9181 aggacagtta taaaattgtc tctgattcgt cttttgcacc ttttgaattt caaaatggta
     9241 agggcaaata cgttggtatt gacatagaat taatcaaagc tattgctaaa caacaaggtt
     9301 tcaaaattga aatcgctaat ccaggtttcg atgctgcctt aaatgctgtg caatctagcc
     9361 aagcagatgg ggtcattgct ggtgcaacta ttactgacgc tcgtaaagct atctttgatt
     9421 tttctgatcc ttattatact tctaatatca ttttagctgt taaagctgga aaaaacatca
     9481 agaactatga agacttagac agaaaaacag tcggtgctaa aaacggcact tcatcttact
     9541 cttggttaaa agaaaacgct cctaaatatg gttataatgt caaggcattt gatgatggtt
     9601 ctagcatgta tgatagctta aattcaggtt ctgtagatgc tatcatggat gatgaggcgg
     9661 ttcttaaata cgctatctct caaggtcgtc gctttgaaac acctcttgag ggcatttcta
     9721 ctggtgaagt tggttttgct gtcaagaaag gaactaatcc agaattaatc gaaatgttca
     9781 acaatggctt agctgctctc aaaaaatctg gtcagtatga tgacattata gataaatacc
     9841 ttgactctaa gaaagctgca actccttctg aaaaaagtgc tgatgagtct actatttcag
     9901 gcctattatc aaataactac aaacaactat tggcaggact tggaaccacg ctcagtttaa
     9961 cccttatttc atttgctatt gctataatta tcgggatcat ctttgggatg atggccgtgt
    10021 caccaactaa atcacttcga ctcatttcaa cggtctttgt ggacgttgtt cgagggattc
    10081 ctttgatgat tgtggctgcc ttcattttct ggggagtacc aaaccttatc gagagtatga
    10141 ccggccacca gtcaccgatt aatgatttct tagctgctac aattgcactg tcacttaatg
    10201 gcggagccta tattgctgaa attgttcgtg gtggtatcga agctgttcca gcagggcaaa
    10261 tggaagctag tcgaagtctt ggtttgtctt acggaaccac gatgagaaaa gtaattctcc
    10321 cacaagctgt gaaactaatg ttacctaact ttatcaacca gtttgttatt tcattgaagg
    10381 atacaacaat cgtctcagca attggtttag tggaactctt ccaaacaggt aaaatcatta
    10441 ttgctagaaa ttaccagtcg ttccgtatgt atgctatttt agcaattatt taccttatca
    10501 tgattacact cttaacaaga cttgcaaaac gtttagaaaa gaggcttaac taatgacaga
    10561 attaaaaatt gatgttcaag gtttacacaa atcttatggt caaaatgaag tcttaaaagg
    10621 aattgatgcc aaattctacg aaggtgatgt cgtttgtatc attggtcctt ctggttctgg
    10681 gaaatcaacc tttctacgta ccctcaacct tctagagacg attaccagtg gtaaggtcat
    10741 ggtggacggt tttgaattat cagatcctaa gactaatatt gacaaggcac gtgaaaatat
    10801 cgggatggta ttccaacact tcaacctttt ccctcacatg actgttcttg agaatattat
    10861 ctttgctcct gttgaattag gtaaagagtc taaagaagtt gctaaaaagc atggcatggc
    10921 acttctagaa aaagtcggac tttctgataa ggccgacgcc ttcccaggaa gtttatccgg
    10981 cgggcaaaaa cagcgtgtcg ccatcgccag aagtttagca atgaacccag atattatgct
    11041 ctttgatgaa ccaacttctg ctcttgaccc cgaaatggtt ggggacgttt tgaacgttat
    11101 gaaagacttg gcagaacaag gcatgaccat gttaattgtt actcacgaaa tgggatttgc
    11161 tcgccaagta gctaaccgtg ttatctttac agacggtggt caattcttag aagatggtac
    11221 tcctgaagag atttttgatc atcctaagca ccctcgtctc attgaatttt tagacaaggt
    11281 tttaaacgtc taatagagca gacaccatac taacttccaa aaaataataa ggcaaggaaa
    11341 cctatctcct tgcctttttt ggttactgtt attattcaaa ccagcaaaat agggatactc
    11401 ttatgactct ctccttcata agagtgtccc ctatgctttt ttatgggcgt ttatgtttag
    11461 tgaggtaata acctaatccc gtaagagcta gtcccgtcac tatgtgtaag tatttgttac
    11521 caaccatcgg actaatggca atgagaaaaa agccaacagc cattaaaaaa gttgctccat
    11581 ttttttctgt catgcaaggt cactcgcttt ttctttattg gccaaaatga caaatggtgc
    11641 ccagataagg aaggcaacaa agaggttaaa cagtgaaacc aaacctgcca taatattacc
    11701 tcc
//
LOCUS       DAXMQE010000048        11670 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.048, whole genome shotgun sequence.
ACCESSION   DAXMQE010000048 DAXMQE010000000
VERSION     DAXMQE010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11670)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11670)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11670
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.048"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            <1..153
                     /locus_tag="ACF4ZO_001675"
     CDS             <1..153
                     /locus_tag="ACF4ZO_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009881107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase"
                     /protein_id="HFD5487191.1"
                     /translation="LAVLVDRGHRELPIRADYVGKNIPTSSVEEIVVEVVEVDGRDRV
                     SIIDPT"
     gene            169..1428
                     /locus_tag="ACF4ZO_001676"
     CDS             169..1428
                     /locus_tag="ACF4ZO_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="solute carrier family 23 protein"
                     /protein_id="HFD5487192.1"
                     /translation="MKDVIYDVEEVPKAGMLVGLSFQHLFAMFGATVLVPILVGIDPS
                     VALLSSGLGTLAHLSVTKFKIPAYMGSSFAYIAAMQLLMRTNGIGAVAQGAMTGGLVY
                     LIVALIVKAIGNDWIDNILPPIVVGPTVMVIGLSLASTAVNDVMLKNGNYNLTYLVIG
                     LVTLLSVIFFNIYGKGIVAIVPLLLGLLVGYVVALLVGVLTGQEIVDFTNVAQAKWFS
                     IPSVEIPFLTYGVKFYPSAILTMAPIAFVTMTEHFGHIMVLNSLTKRDYFKDPGLEKT
                     LTGDGFAQIIAGFLGAPPVTSYGENIGVMALNKIFSVYVIAGAAVIAALLSFIGKVSA
                     LIQSIPTPVIGGISVALFGVIASSGLKILIESKVDMDNKKNLLIASVILVSGIGGLML
                     QVNGLQISGVAFSTLLGIILYQVLPEK"
     gene            1489..2424
                     /locus_tag="ACF4ZO_001677"
     CDS             1489..2424
                     /locus_tag="ACF4ZO_001677"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004070 - aspartate carbamoyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0016597 - amino acid binding [Evidence
                     IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HFD5487193.1"
                     /translation="MSVVNNRVALTNLVSMEALTTEEVLGLINRGSEYKAGKVVISDH
                     QKDLVANLFFENSTRTHKSFEVAEKKLGLTVLDFNADASAVNKGESLYDTVLTMSALG
                     TDICVIRHPEDDYYKELVESPTITASIVNGGDGSGQHPSQCLLDLLTIYEEFGRFEGL
                     KIAIAGDLTHSRVAKSNMQILKRLGAELYFYGPEEWYSEAFNAYGTYIAIDQIIKELD
                     VLMLLRVQHERHDGHQSFSKEGYHQAFGLTQERYQQLKDSAIIMHPAPVNRDVEIADS
                     LVEAPKARIVSQMANGVFVRMAIIEAILNGRNKNS"
     gene            2468..3550
                     /locus_tag="ACF4ZO_001678"
     CDS             2468..3550
                     /locus_tag="ACF4ZO_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004088 - carbamoyl-phosphate synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl phosphate synthase small subunit"
                     /protein_id="HFD5487194.1"
                     /translation="MTKRLLILEDGTIFEGEPFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLIGNYGINRDDYESISPTCKGVVVSEVSRLASNWRKQMTLDAFLK
                     IKGIPGISGIDTRALTKIIRQHGTMKATMADDGDSIQHLKDQLRATVLPTNTIEQVST
                     KTAYPAPGIGKNIVLVDFGLKHSILREFSKRQCNITVVPFNITAEEVLQLNPDGLMLS
                     NGPGNPEDLPEALDMIRGVQGKIPIFGICMGHQLFSLANGAKTCKMTFGHRGFNHAVR
                     EIATGRIDFTSQNHGYAVERSSLPDTLMVTHEDINDKTVEGVKHRDFPAFSVQFHPDA
                     APGPHDASYLFDEFLEMIDSWRCTSK"
     gene            3796..6972
                     /gene="carB"
                     /locus_tag="ACF4ZO_001679"
     CDS             3796..6972
                     /gene="carB"
                     /locus_tag="ACF4ZO_001679"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HFD5487195.1"
                     /translation="MPKRKDIQKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYKV
                     ILVNSNPATIMTDKEIADKVYIEPLTLEFVNRIIRKERPDAILPTLGGQTGLNMAMAL
                     SKAGILDDLEIELLGTKLSAIDQAEDRDLFKQLMQELDQPIPESTIVKTVDEAVTFAR
                     DIGYPVIVRPAFTLGGTGGGICSSEEELCEITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPTQTLSDIENQMLRDASLKIIRALK
                     IEGGCNVQLALDPYSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEM
                     INPITGTTYAMFEPALDYVVAKIPRFPFDKFEHGERQLGTQMKATGEVMAIGRNLEES
                     LLKACRSLEIGVCHNEMTSLSNISDEELVTKVIKAQDDRLFYLSEAIRRGYSIEELES
                     LTKIDLFFLDKLLHIVEIEQELQMHVDHLESLKKAKRYGFSDQKIAEIWQKDESDIRA
                     MRHSHSLYPVYKMVDTCAAEFDAKTPYFYSTYELENESVQSNKESILVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQKAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAQSLSDAGVTILGTQVEDLDRAEDRDLFEKALKELGIPQP
                     QGQTATNEEEALEAAKKIGFPVLVRPSYVLGGRAMEIVENKEDLREYIRTAVKASPEH
                     PILVDSYIFGKECEVDAISDGKSVLIPGIMEHIERAGVHSGDSMAVYPPQQLSKQIQE
                     TIAEYTKRLAIGLNCIGMMNVQFVIKNEQVYVIEVNPRASRTVPFLSKVTGIPMAQIA
                     TKLILGQTLKDLGYEDGLYPQSQLVHIKAPVFSFTKLAQVDSLLGPEMKSTGEVMGSD
                     TSLEKALYKAFEANNSHLSEFGQIVFTIADDSKAEALSLARRFKAIGYQIMATQGTAA
                     YFAEQGLSACLVGKIGDAANDIPTLVRHGHVQAIVNTVGIKRTADKDGQMIRSSAIEQ
                     GVPLFTALDTAKAMLTVLESRCFNIEAI"
     gene            7179..8450
                     /locus_tag="ACF4ZO_001680"
     CDS             7179..8450
                     /locus_tag="ACF4ZO_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_function: GO:0042802 - identical protein binding
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HFD5487196.1"
                     /translation="MSKRGKIKITTKTKLITASVITLVLIITGVVLWKQQQNTLTADI
                     AKEPYSTVSVTEGSIASSTLLSGTVKALSEEYIYFDANKGNDATVTVKVGDQVTQGQQ
                     LVQYNTTTAQSAYDTAVRSLNKIGRQINHLKTYGVPAVSTETNKDEATGEETTTTVQP
                     SAQQNANYKQQLQDLNDAYADAQAEVNKAQIALNDTVVISSVSGTVVEVNNDIDPSSK
                     NSQTLVHVATEGQLQVKGTLTEYDLANVKVGQSVKIKSKVYSNQEWTGKISYVSNYPT
                     ESNAGSTTPAGSTGAGSSTGAAYDYKIDIISPLNQLKQGFTVSVEVVNEAKQALVPLT
                     AVIKKDKKHYVWTYDDATGKAKKVEVTLGNADAQQQEIHKGVAVGDIVIANPDKNIKP
                     DKKLEGVISIGTNTKPEKDSQSKNKKSGVDK"
     gene            8450..9160
                     /locus_tag="ACF4ZO_001681"
     CDS             8450..9160
                     /locus_tag="ACF4ZO_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD5487197.1"
                     /translation="MSHEKKQLMQLSNIVKSYQNGDQVLKVLKGINLTVYEGEFLAIM
                     GPSGSGKSTLMNIIGLLDRPTSGDYTLHNTKIEILNDRELANVRNDEIGFVFQQFFLL
                     AKLTALQNVELPLIYAGVNVSKRREQAKQFLEKVGLGRRIKHLPSELSGGQKQRVAIA
                     RALVNDPSIILADEPTGALDTKTGQQIMELLTELNKEGKTIIMVTHEPEIADFATRKI
                     IIRDGDITTDTTASVVID"
     gene            9172..10392
                     /locus_tag="ACF4ZO_001682"
     CDS             9172..10392
                     /locus_tag="ACF4ZO_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD5487198.1"
                     /translation="MENWKFALSSIWGHKMRSILTMLGIIIGVAAVVIIMGLGNAMKN
                     SVTSTFSSKQKDIQLYFQEKGEEEDLYAGLHTHENNHEVKPEWLEQIVKDIDGIDSYY
                     FTNSATSTISYEKKKVDNASIIGVSKDYFNIKNYDIVAGRTLTDNDYSNFSRIILLDT
                     VLADDLFGEGNYKSALNKVVSLSDKDYLVIGVYKTDQTPVSFDGLSGGAVMANTQVAS
                     EFGTKEIGSIYIHVNDIQNSMNLGNQAADMLTNISHIKDGQYAVPDNSKIVEEINSQF
                     SIMTTVIGSIAAISLLVGGIGVMNIMLVSVTERTREIGLRKALGATRLKILSQFLIES
                     VVLTVLGGLIGLLLAQLSVGALGNAMTLKGACISLDVALIAVLFSASIGVFFGMLPAN
                     KASKLDPIEALRYE"
     gene            10646..>11670
                     /locus_tag="ACF4ZO_001683"
     CDS             10646..>11670
                     /locus_tag="ACF4ZO_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphoryl diester phosphodiesterase
                     membrane domain-containing protein"
                     /protein_id="HFD5487199.1"
                     /translation="MTFLSDLISLMTKIRLSWVIKAGIFQLLFVTIANIVLSEFFYFI
                     LDVTGQYHLDKDNVVTFLKNPIALALLGAYLFLLAAFIHLEFFALYRIIADQEISFYL
                     FRKQFSYYLRGLWKTFSGYQLLLFLLYILLTIPVLHIGLSSVITQKLYLPEFIVGELS
                     KITSTKYLLYGSLILVFYLNLRLVYFLPLIAINHRTVAQAWRESWQKTKKKHILLWMK
                     LFAINGLTLVVLSLAISMILIFVDMFNPKGNNIIVQLGALTFTWELIFFTTIFFKLCS
                     AMILKEAIEPQKQYDEPRRSNKAYVVIFIVVTVGFAYQSLERLTFFDTSHSKTVIAHR
                     GLVSAGV"
BASE COUNT         3718 a         1870 c         2423 g         3659 t
ORIGIN      
        1 ctagctgttt tggtggatcg tggccatcgg gaattaccga ttcgcgcgga ttacgttggg
       61 aaaaatattc caacaagcag tgtagaagaa attgttgttg aggttgtcga agtcgatggc
      121 cgtgatcgtg ttagcattat tgacccaaca taagaaagag gttttactgt gaaagatgtc
      181 atttatgatg tggaagaagt gccaaaggca ggtatgttag ttggtttgtc ctttcagcac
      241 ttatttgcta tgtttggtgc gactgttctg gttcccattc tagttggaat tgacccatca
      301 gttgctttgt tatctagtgg tttaggaacc cttgcccact tatcagtgac caaatttaaa
      361 attccagcct acatgggctc aagttttgct tatatagcag ctatgcagtt actgatgagg
      421 acaaatggta ttggtgctgt agctcaaggg gctatgacag gaggtctcgt ttacctgatt
      481 gtagctttga ttgttaaagc tattggcaat gattggattg ataacatctt accaccgatt
      541 gtggttggtc cgactgttat ggtcattggt ctaagcctag cttctacagc tgttaatgat
      601 gtcatgctaa aaaatgggaa ctataatctg acttatcttg ttattgggtt agtcacctta
      661 ttatcagtta tttttttcaa tatttatggt aagggaattg ttgctattgt accgctttta
      721 ttagggctat tagttggtta tgttgtagcc cttttagtgg gtgttctcac cggtcaagaa
      781 attgttgatt ttaccaatgt ggctcaggcc aaatggttta gtatcccatc agtggaaatt
      841 cctttcttaa cctacggggt taaattctac ccaagtgcca ttttaactat ggcacccatt
      901 gcctttgtta caatgacaga acattttgga cacattatgg tcttaaatag tttgacaaaa
      961 agagattatt tcaaggatcc aggacttgaa aagactttaa ctggtgatgg ttttgcgcaa
     1021 atcattgccg gcttcttagg ggcacctccg gtcacttctt atggtgaaaa catcggtgta
     1081 atggctttga ataaaatatt ctcggtctat gttattgcag gtgccgcagt gattgccgct
     1141 ctcctcagtt ttatcggtaa ggtgtcagcc ttaattcaat ctattccaac accagttatt
     1201 ggaggtatat cagttgcctt gtttggtgtg atagcttcta gcggtttgaa aatcttgatt
     1261 gaatccaaag ttgatatgga taataagaaa aacttattga ttgccagtgt cattttggtc
     1321 tctgggattg gaggattgat gcttcaagta aatggtcttc aaatttcagg tgtcgctttc
     1381 tcaacacttc ttggcatcat cttatatcag gtacttcctg aaaaatagga agaattgttg
     1441 ttagaccact tacatagtca tcagtcgtta gtgataaagg ggataatcat gtcagttgta
     1501 aataatcgcg ttgcacttac caatttagtt tcaatggaag cattaaccac cgaagaagtt
     1561 ttaggtctta tcaaccgtgg ttcagaatat aaggctggta aggttgttat ttcggatcat
     1621 caaaaggatc ttgttgccaa tttattcttt gaaaactcca cccgaaccca taagtctttt
     1681 gaagtggctg agaagaaact cggcttgaca gttcttgatt tcaatgctga tgcaagtgcg
     1741 gttaacaagg gagaaagttt gtatgatact gtgttaacca tgagtgcact tggaacagac
     1801 atctgtgtga ttcgtcaccc agaagatgat tattacaagg aattagtaga aagtccaact
     1861 attacagctt ccattgtcaa tggaggtgat ggttctggac aacatccgag tcaatgttta
     1921 cttgacttat taaccatcta tgaagaattt ggacgctttg aaggcttaaa gattgcgatc
     1981 gctggtgact taactcactc tagggtggca aagtccaaca tgcaaatcct caaaagatta
     2041 ggagcagagc tttatttcta tggacctgaa gaatggtatt cagaagcctt taatgcttac
     2101 ggcacttata ttgctattga ccagattatt aaggaattgg atgttcttat gttgctgcgt
     2161 gtacagcacg aacgccatga cggccatcag agtttttcaa aagaaggtta ccatcaagcg
     2221 tttggattga cacaggaacg ttaccaacaa ttaaaagatt ctgctattat tatgcatcca
     2281 gctccagtta atcgggatgt ggaaattgca gatagtttgg tggaagctcc taaagcgaga
     2341 attgtatctc agatggctaa tggtgtcttt gttcgcatgg ctattattga agccattttg
     2401 aatggtagaa ataaaaactc atgatgaaag attaaagcat gtttagaagg taggaaaagg
     2461 taggaaaatg acaaaacgat tacttatttt agaagacggc actatttttg aaggagaacc
     2521 ctttggtgct gatattgatg tgactggtga aattgtcttt aatacaggaa tgacaggcta
     2581 ccaagaatcc atcactgacc aatcctacaa tgggcaaatt ttaaccttta cttatccttt
     2641 gattggaaat tatgggatta atcgagatga ctatgagtcc atttcaccca cctgtaaagg
     2701 ggttgttgtg tctgaagtca gtcggttggc aagtaattgg cgcaagcaaa tgacgctaga
     2761 tgcgttcttg aaaataaaag ggattccagg gatttcggga attgatacga gagctttgac
     2821 caaaattatt cggcaacacg gtaccatgaa agctacgatg gcagatgatg gagatagtat
     2881 ccagcattta aaagatcaac tgcgtgcaac agtcttaccg actaacacca ttgaacaagt
     2941 gtcaactaaa acagcttatc ctgcaccagg gatcgggaaa aatattgtat tggttgattt
     3001 tggtttaaaa cattctattt taagagaatt ttctaaaaga caatgtaata tcaccgttgt
     3061 ccctttcaac atcactgcag aagaagtgct ccaactaaat ccggatggct tgatgctatc
     3121 taatggccca ggaaacccag aagatttgcc agaggctcta gacatgattc gtggggtaca
     3181 aggtaagatt cctatttttg gtatttgtat gggacatcaa ctctttagtc tagcaaatgg
     3241 tgccaagact tgtaaaatga cctttggtca tcgtggcttt aaccatgccg ttagagaaat
     3301 tgcaacggga agaattgatt ttaccagcca aaaccatggt tatgccgttg aacgtagtag
     3361 tctacctgat actttaatgg ttacgcatga agacattaac gataagacgg tcgaaggagt
     3421 gaaacataga gattttccag ctttttcagt ccaatttcac cctgatgcgg ctccaggacc
     3481 tcatgatgcc agctacttat ttgacgaatt tttggaaatg attgattctt ggagatgtac
     3541 gagtaaatag taaatcagtt gcaatttcac gactatatca cctcttgtta ctctatttat
     3601 taacatttac agttgattta gtaccctatc aaaaatatta tttaatgttg ctctgtgagg
     3661 caacaaatag agaaaggaat gcaaggagaa cacaagtaaa taatttagta aaaagttagg
     3721 ttttcaaaga gataaagctc ttattgagaa gtgctgactt taccgcttct tgtggtattc
     3781 ttggtatcat taattatgcc aaaacgaaaa gatattcaaa aaatcatggt tatcgggtct
     3841 ggcccgatta ttattggaca agctgctgaa tttgattatg cagggactca ggcctgtttg
     3901 gctctaaaag aagaaggcta caaggtcata cttgttaatt caaatcctgc aacgattatg
     3961 acagataaag aaatcgctga taaggtatat attgagcctt tgactcttga atttgttaat
     4021 cgtatcattc gaaaagaaag gccagatgcc atactgccaa ccttaggtgg ccaaacgggc
     4081 ctcaatatgg caatggcatt atctaaagct ggtattcttg atgatttaga gattgaattg
     4141 ttaggtacta agttatctgc aattgatcag gcagaagaca gagacctttt caaacaatta
     4201 atgcaagaac tagaccaacc cattccagaa tctacaattg ttaaaacagt tgatgaagct
     4261 gttacatttg ctagagatat cggttatcca gtcattgtgc gcccagcttt tactcttggt
     4321 ggaactggtg gaggaatatg tagtagtgaa gaagaacttt gtgaaattac tgaaaacggc
     4381 ctaaagttat caccggtcac acagtgtttg attgaacgct caattgctgg cttcaaagaa
     4441 attgaatacg aagtaatgcg agatagtgct gataatgcgc tggttgtttg taatatggaa
     4501 aactttgatc ccgtagggat tcacacagga gattctattg tatttgcacc aacacagacc
     4561 ctttctgata ttgaaaatca aatgttacgt gatgctagtt taaaaataat tcgagctctg
     4621 aaaattgaag gtggctgtaa cgtccagtta gcactagatc cttatagttt caaatattat
     4681 gttattgaag taaatcctag agtgtctcgt tcctctgccc ttgcttcaaa agcaacaggt
     4741 tatcccattg ccaaattggc tgcaaagatt gctgttggcc taacacttga tgaaatgatt
     4801 aaccctatca caggcactac ttacgctatg tttgaacctg cccttgatta cgttgttgct
     4861 aaaattccgc gttttccgtt tgataaattt gaacatggtg aacgccaact gggaactcaa
     4921 atgaaagcaa caggtgaagt catggctatt ggccgtaatt tggaagagtc cttactaaaa
     4981 gcctgtcgtt ctttagaaat tggtgtttgc cataatgaga tgacaagttt aagtaacatt
     5041 agtgatgaag agttagtgac taaagtgatt aaagctcaag atgatcgact tttttacttg
     5101 tcagaagcaa tacgacgagg ttatagtatt gaagaacttg agagcttgac caagattgat
     5161 ttatttttct tggataaatt acttcatatt gttgaaatag agcaagaatt acaaatgcat
     5221 gttgaccatt tggaaagcct caaaaaagca aagcgttatg gattttcaga tcaaaaaatt
     5281 gcagaaattt ggcaaaagga tgaaagtgat atcagagcga tgagacattc tcatagcctg
     5341 tatcctgtct ataaaatggt agatacttgt gcagctgaat ttgatgctaa aaccccttat
     5401 ttttattcaa catatgagtt ggaaaatgaa tctgttcagt cgaataaaga atcaatttta
     5461 gttttaggtt caggccctat tcgtattggt caaggggttg aatttgacta cgcaacggtt
     5521 cattctgtta aagccatcca aaaagctggc tatgaagcca ttatcatgaa ttcaaatccg
     5581 gagactgtat ctacagattt ttcggtatca gataaattat attttgaacc gttaaccttt
     5641 gaagacgtca tgaatgtgat agatttagag cagcctaagg gagtgatagt tcagtttgga
     5701 ggacaaactg ctattaactt agcacaatca ctttctgatg cgggtgttac aatattagga
     5761 acacaagtag aggatttgga tagggctgaa gacagagatt tatttgaaaa ggcgttgaaa
     5821 gagcttggaa tcccacaacc acaaggtcaa acggcaacta atgaagaaga agctttagag
     5881 gcagctaaaa aaattggttt tccagtctta gttagacctt cttacgtact tggtggccgg
     5941 gctatggaaa ttgttgaaaa caaagaagat cttagagaat atataagaac agcggttaaa
     6001 gcaagtcctg aacatcctat cttagtggac tcttatattt tcggtaagga gtgtgaagtg
     6061 gatgccattt cagatggaaa atcagtctta attcctggta ttatggagca catcgaaaga
     6121 gcaggtgttc attcaggaga ttcaatggca gtttatccgc cacagcaatt atctaagcaa
     6181 attcaagaaa caatagctga gtatactaaa cgtttagcca ttgggttaaa ttgtattggt
     6241 atgatgaatg ttcaatttgt tattaaaaat gaacaagtct atgttattga agtgaatcca
     6301 cgcgctagtc gtaccgtgcc tttcttatca aaagtaacag gtattccgat ggctcagatt
     6361 gctactaagt tgattttagg tcaaacatta aaggatctag gatatgaaga tggcctttat
     6421 ccccaaagtc aactggtgca tatcaaagcg cctgtgtttt catttacaaa gttggcacag
     6481 gttgatagtc ttttaggtcc tgaaatgaaa tcaactggag aagtaatggg ttcggatact
     6541 agtcttgaaa aagcacttta taaagcgttt gaagccaata attctcattt atcagaattt
     6601 ggtcaaattg tctttactat agcagatgat agtaaggcag aagctctaag tctagcaaga
     6661 cgatttaagg cgattggcta tcaaattatg gctactcaag gtacagcagc ttactttgct
     6721 gagcaaggct taagcgcgtg tttagttgga aaaattggtg atgctgccaa tgacatcccg
     6781 acactcgtgc gacatggtca cgttcaggca attgttaata cagttggaat taaacgcaca
     6841 gctgataaag acggacagat gattagaagt tcagctattg aacaaggagt tcctttattt
     6901 acagctttag atactgcaaa agctatgtta acggttttag aaagcagatg ctttaacatc
     6961 gaagcgatat aaaaattaaa aaaatcattt ttaagaaaac ttaaaaatga tttttttaga
     7021 ttataatgac aaaagtttca gtaagctatt aatttgtcat agcatataag tcattatttt
     7081 gtggcttgtt ttcgactaag ggctaagaat ttcttgacaa caatataaaa aggtcatata
     7141 cttgtcttat acaaatagta caaaagggga ggatagaaat gtctaaaaga ggaaaaatta
     7201 aaataacaac gaaaacaaag cttattacag ctagtgttat aacgctagta ttaattataa
     7261 ctggagtagt cttgtggaaa caacaacaaa atacgctaac agctgatatc gctaaagaac
     7321 cttactctac tgttagtgta actgaaggga gtattgcttc ttcgacttta ctctcaggta
     7381 ctgtaaaggc tttatcagag gaatatattt attttgatgc taataaagga aatgatgcaa
     7441 ctgttacagt taaagtaggt gatcaggtaa cgcagggcca gcaattagtt caatataata
     7501 caacaacagc tcagtcagct tatgatactg ctgttaggag tcttaacaag attggccgac
     7561 aaattaatca tcttaaaaca tacggagttc ctgctgttag tacagaaact aataaagatg
     7621 aagctaccgg tgaagagacg acaacaacag ttcaaccatc agctcagcaa aatgctaatt
     7681 ataaacagca gctgcaagat ttaaatgatg cttatgcaga tgcacaagca gaagtaaata
     7741 aagcgcagat agcgttaaat gatacagtag ttatcagtag tgtctctgga actgttgtgg
     7801 aagtaaataa tgatattgat ccttcttcaa agaacagtca aacacttgtt cacgtagcaa
     7861 ccgaaggaca gcttcaggtg aaaggaacat tgacagagta tgatttagca aacgttaagg
     7921 ttggtcaatc tgtaaaaatt aagtctaaag tttattctaa tcaagaatgg actggaaaaa
     7981 tatcatatgt ttcaaactat ccaactgagt ctaatgcagg ttcaacaacg ccagcaggta
     8041 gcactggagc gggaagttct acaggagctg cctatgatta caagattgat attataagtc
     8101 ctcttaacca gcttaaacaa ggtttcactg tttctgttga ggttgttaat gaagctaaac
     8161 aggccttagt tcctttaacg gctgttatta agaaagataa aaaacactat gtttggactt
     8221 atgatgatgc tactggcaaa gccaaaaaag tagaggtgac acttggaaac gcagatgcac
     8281 aacaacaaga aattcataaa ggagtagctg ttggtgacat tgttattgcc aatccagata
     8341 aaaatatcaa accggataaa aaactagaag gggttatttc aataggtacc aacacaaaac
     8401 cggaaaaaga ttctcaatca aagaataaaa aatcaggggt ggataaatag tgtcgcatga
     8461 aaaaaaacaa ttaatgcaat tatcaaatat tgtgaagagc tatcaaaatg gggatcaagt
     8521 tcttaaagtt ttgaaaggta ttaatttaac agtatatgag ggtgaatttt tagctattat
     8581 gggtccgtct ggctcgggaa aatcaacact aatgaatatt attggtttat tagatcggcc
     8641 aacatccgga gattacacat tacataatac taaaatagaa atccttaatg atcgtgaatt
     8701 agcaaacgta cgaaatgatg aaatcggctt tgtctttcaa caattctttc tgttagctaa
     8761 attaactgca ttacaaaatg ttgagttgcc tcttatttat gctggtgtaa acgtctcaaa
     8821 aagacgtgaa caagctaagc aatttcttga aaaagtagga cttggacgac gtatcaaaca
     8881 tctaccgtca gaactgtcag gaggtcaaaa gcaaagggtg gctatcgcac gagctttagt
     8941 aaatgaccca tctattattt tagcggatga accaacaggc gcactagata ctaaaacagg
     9001 tcagcaaatt atggaactct tgacagagtt aaacaaagaa ggtaaaacaa ttattatggt
     9061 tactcatgaa ccagaaattg ctgattttgc aactcggaaa attattattc gtgatggtga
     9121 tatcacaacg gatactacag ctagtgttgt tattgactag gaggaaaaat aatggaaaat
     9181 tggaaattcg ctcttagctc aatttggggg cataagatgc gctcaatcct gacaatgttg
     9241 ggaattatca tcggtgtagc agcagttgtg attattatgg ggttgggaaa tgctatgaaa
     9301 aatagtgtaa caagcacatt ttctagcaaa caaaaagata ttcaactcta ttttcaagaa
     9361 aaaggagaag aagaagacct gtatgccgga ttgcacacgc atgaaaataa tcacgaagtg
     9421 aagccagagt ggttagaaca aattgttaaa gatattgatg gtattgattc ttattacttt
     9481 accaattctg ctacttctac tatttcgtat gaaaaaaaga aagtagacaa tgcttcgatc
     9541 ataggggtaa gtaaagatta ttttaatata aaaaactatg atatcgtagc tggtcgtaca
     9601 ctaacagata atgattattc taatttttcg cgtatcattc ttttagatac agtattagcc
     9661 gatgacctat ttggcgaagg taattataag tcagctttaa ataaagtggt aagtttatct
     9721 gataaagatt atttagttat tggtgtttat aaaactgatc agacgccagt ttcttttgat
     9781 ggattatcag gcggcgctgt catggcaaat actcaggtag cttcagagtt tggcaccaaa
     9841 gaaataggat ctatctacat tcatgtgaac gatattcaaa acagtatgaa cttaggaaat
     9901 caagcagctg atatgctaac caacatatcg catattaaag atggacagta cgctgttcct
     9961 gataatagca aaatcgttga agaaatcaat agtcagttca gtatcatgac aacagtcata
    10021 ggttcaattg cagcgatctc tcttttagtg ggaggaattg gtgttatgaa tattatgttg
    10081 gtatctgtca cagagcgaac tagggaaatt ggtttacgta aagcacttgg tgcaacacgc
    10141 ctgaaaattt tatcacaatt tttgattgaa tccgttgttc taacagttct tggaggcttg
    10201 ataggattat tattagctca attaagtgta ggggctttag gaaatgcgat gacattaaaa
    10261 ggagcttgta tttctcttga tgtggcctta atagcagttt tattttctgc ctcaataggt
    10321 gtcttttttg gaatgttgcc agctaataaa gctagtaagt tagatccaat tgaggcatta
    10381 cgttatgaat agaatagttc gtatcaatta atctatagac gctgactagt ttaacgtctg
    10441 attatatcta gtttttgtat tagcacagta gttatatcat tgaagtgtta gtgcattttt
    10501 tgaggtgata atatctagca aagctatcat tggtatgatg atgtggatag cgtataagtg
    10561 atacatctct tatttctagc tgaacttcgg ttcggctagg aagttgtcag gcaatgagtt
    10621 gtttaaaata aaggagatta gttcaatgac atttttatct gatttgatat cattaatgac
    10681 aaaaatcaga ttatcttggg taataaaggc gggtattttt caattattat ttgtaacgat
    10741 tgctaatatt gtcttatcag aatttttcta ttttatatta gacgttactg gtcaatatca
    10801 tttagataaa gacaatgttg tgactttttt aaaaaatcct atagcacttg ctttattagg
    10861 tgcctattta tttttattag ctgcttttat tcaccttgag ttttttgctc tatatcgaat
    10921 tattgcggat caagaaatta gtttctatct ttttagaaaa cagttttctt attacctaag
    10981 ggggctttgg aaaacatttt ctggttacca attattactt tttttgcttt atatcctact
    11041 gactattcca gtcttacata ttggtttatc ttctgtgatt actcaaaagc tttatcttcc
    11101 agaatttatt gttggggaat tatcaaagat aactagcaca aagtacttgc tttatggcag
    11161 tcttattctt gtgttttacc ttaacctaag attagtatat tttttaccat tgatagcaat
    11221 caaccatcgt acggttgctc aagcatggag agagagttgg caaaagacta aaaagaaaca
    11281 tatattgtta tggatgaaac tttttgcaat caatggtctt acgcttgtag tcttatcgct
    11341 agctatttcc atgattctta tttttgttga tatgtttaat cctaagggga ataatattat
    11401 tgttcagctg ggagctttga cctttacatg ggagctcatt ttttttacta ctattttttt
    11461 taaactctgt tcagcgatga ttttaaaaga ggcaattgaa ccacaaaagc aatatgatga
    11521 gccaagaaga agtaataagg catatgttgt aatctttatc gtggtgacag taggttttgc
    11581 ttatcaatct cttgaacgtt taactttttt tgacacatct cactctaaga cagttatcgc
    11641 gcatagagga cttgtatcag caggtgtaga
//
LOCUS       DAXMQE010000049        10084 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.049, whole genome shotgun sequence.
ACCESSION   DAXMQE010000049 DAXMQE010000000
VERSION     DAXMQE010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10084)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10084)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10084
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.049"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            43..264
                     /locus_tag="ACF4ZO_001684"
     CDS             43..264
                     /locus_tag="ACF4ZO_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Paratox"
                     /protein_id="HFD5487200.1"
                     /translation="MLTYDEFKQAIDDGYIVGDTVMIVRKNGQIFDYVLPNEKIRDWE
                     VVTEEKVEEVMVELDYIIMKKTLSRQKNN"
     gene            complement(384..731)
                     /gene="ssrA"
                     /locus_tag="ACF4ZO_001685"
     tmRNA           complement(384..731)
                     /gene="ssrA"
                     /locus_tag="ACF4ZO_001685"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            823..1437
                     /locus_tag="ACF4ZO_001686"
     CDS             823..1437
                     /locus_tag="ACF4ZO_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HFD5487201.1"
                     /translation="MTKRNSKAYILWQKIIKILGIIALIGTFFLAFWLYRLGILNDSN
                     ALKDLVQRYRLWGPFVFIVVQIIQIVFPVIPGGLTTVAGFLIFGPVTGFIYNYVGIII
                     GSIVLFLLVKTYGRKFILLFVNDKTFYKYERRLETPGYEKLFIFCMASPVSPADIMVM
                     ITGLTDMSLKRFVTILLITKPISIIGYSYLFIFGKDVISWFLQH"
     gene            complement(1564..2349)
                     /locus_tag="ACF4ZO_001687"
     CDS             complement(1564..2349)
                     /locus_tag="ACF4ZO_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD5487202.1"
                     /translation="MFGKLLKYEFRSIGKWYFALNAFVIAIAAILSFTIKLFAQSNSD
                     GLFGVLTNKMLPLTLGLTFGSLIAGSLLSTLLIIIKRFSKSVFGREGYLTLTLPVNSH
                     QIILSKLLASFICSVFNTIILAFAIAIVIVPMFNVNELLEGFFNSFKMDYFINMLTVL
                     AYVLLSTFTSILLIYLSISIGQLFSNRRGLMAFIAYFILVILISVAATYVHNHIFNIN
                     TSADSFPFTEQKTTYLLILEQFIEMIMFYLATNFIIKNKLNLQ"
     gene            complement(2359..3057)
                     /locus_tag="ACF4ZO_001688"
     CDS             complement(2359..3057)
                     /locus_tag="ACF4ZO_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD5487203.1"
                     /translation="MAHLLQLHHVSKSYREKKAIDDLTITIPNGKIIGLLGPNGSGKT
                     TLIKLINGLLQPNKGEIVIDGYRPCVETKKIISYLPDTTYLNENMRIKDMLEFFSDFY
                     SDFDKSKATSLLRDLELDPEDRFKTLSKGNKEKVQLILVMSRKARLYVLDEPIGGVDP
                     AARDYILKTIINSYCENASVIISTHLISDIEPILDEVIFLKQGRLFLSGNADDLRQEY
                     QQSIDSLFRETYKV"
     gene            complement(3057..3428)
                     /locus_tag="ACF4ZO_001689"
     CDS             complement(3057..3428)
                     /locus_tag="ACF4ZO_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFD5487204.1"
                     /translation="MSWKFDEKSPIYAQIAQHVMMQIISQEIKSGDQLPTVREYAEIA
                     GVNPNTMQRAFTELEREGMVYSQRTAGRFVTDDQKLIARKRRELAISELESFITNMTK
                     MGFSHTEIIPVLTSFLKEDSQ"
     gene            3613..6723
                     /locus_tag="ACF4ZO_001690"
     CDS             3613..6723
                     /locus_tag="ACF4ZO_001690"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HFD5487205.1"
                     /translation="MFAQLDTKTVYSFMDSLIDLNHYFERAKQFGYHTIGIMDKDNLY
                     GAYHFIKGCQKNGLQPVLGLEVEILYQERQVLLNLIAQNTQGYHQLLKISTAKMSGKL
                     HMDYLCQHLEGIAVIIPSKGWSDTLVVPFDYYIGVDQYTDLSHMDSKRQLIPLRTVRY
                     FAQDDMETLHMLHAIRDNLSLAETPVVESDQELADCQQLTTFYQTHCPQALQNLEDLV
                     SGIYYDFDTNLKLPHFNRDKSAKQELQELTEAGLKEKGLWKEPYQSRLLHELIIISDM
                     GFDDYFLIVWDLLRFGRSKGYYMGMGRGSAAGSLVAYALNITGIDPVQHDLLFERFLN
                     KERYSMPDIDIDLPDIYRSEFLRYVRNRYGSDHSAQIVTFSTFGPKQAIRDVFKRFGV
                     PEYELTNLTKKIGFKDSLATVYEKSISFRQVINSRTEFQKAFAIAKRIEGNPRQTSIH
                     AAGIVMSDDTLTNHIPLKSGDDMMITQYDAHAVEANGLLKMDFLGLRNLTFVQKMQEK
                     VAKDYGCQIDIAAIDLEDPQTLALFAKGDTKGIFQFEQNGAINLLKRIKPQRFEEIVA
                     TTSLNRPGASDYTTNFIKRREGQEKIDLIDPVIAPILEPTYGIMLYQEQVMQIAQVYA
                     GFTLGKADLLRRAMSKKNLQEMQKMEEDFIASAKHLGRAEETARGLFKRMEKFAGYGF
                     NRSHAFAYSALAFQLAYFKAHYPAVFYDIMMNYSSSDYITDALESDFQVAQVTINSIP
                     YTDKIEASKIYMGLKNIKGLPRDFAYWIIEQRPFNSVEDFLTRTPEKYQKKVFLEPLI
                     KIGLFDCFEPNRKKILDNLDGLLVFVNELGSLFSDSSFSWVDTQDYSATEKYSLEQEV
                     VGVGMSKHPLIDIAEKSIQTFTPISQLVKESEAVVLIQIDSIRIIRTKTSGQQMAFLS
                     VNDTKKKLDVTLFPQEYAIYKDQLKEGEFYYLKGRIKERDHRLQMVCQQVQMAISQKY
                     WLLVENHQFDSQISEILGAFPGTTPVVIHYQKNKETIALTKIQVHVTENLKEKLRPFV
                     LKTVFR"
     gene            6803..7816
                     /gene="pfkA"
                     /locus_tag="ACF4ZO_001691"
     CDS             6803..7816
                     /gene="pfkA"
                     /locus_tag="ACF4ZO_001691"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006002 - fructose 6-phosphate metabolic
                     process [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HFD5487206.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRKAISEGMEVYGINRGYAGM
                     VDGDIFPLGSKEVGDKISRGGTFLYSARYPEFAQLEGQLAGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAVGIPGTIDNDIAGTDYTIGFDTAVNTAVEAIDKLRDTSSSH
                     GRTFVVEVMGRNAGDIALWAGIASGADQIIVPEEEFDIEKVASTIQYDFEHKGKNHHI
                     IVLAEGVMSGEAFAQKLKEAGDKSDLRVTNLGHILRGGSPTARDRVIASWMGSHAVEL
                     LKEGKGGLAVGIHNEELVESPILGTAEEGALFSLTEEGKIIVNNPHKARLDFAALNRS
                     LSQ"
     gene            7879..9381
                     /gene="pyk"
                     /locus_tag="ACF4ZO_001692"
     CDS             7879..9381
                     /gene="pyk"
                     /locus_tag="ACF4ZO_001692"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018366040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004743 - pyruvate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0030955 - potassium ion binding [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HFD5487207.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKYGEDGYWAGQLDVEESAKKIAE
                     LIEAGANVFRFNFSHGDHKEQGDRMATVRLAEEIARQKVGFLLDTKGPEMRTELFADD
                     AKEFSYVTGEKIRVATTQGIQSTRDVIALNVAGSLDIYDEVEVGHTILIDDGKLGLKV
                     IDKDIATRQFIVEVENDGIIAKQKGVNIPNTKIPFPALAERDNADIRFGLEQGLNFIA
                     ISFVRTAKDVEEVREICRETGNDHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVFQKMIITKVNAAGKAVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPVESVRTMATIDRNAQTLLNEYGRLDSSAFPRTNKTDVIASAVK
                     DATHSMDIKLVVTITETGNTARAISKFRPDADILAVTFDEKVQRALMINWGVIPVLAE
                     KPASTDDMFEVAERVAVEAGLVQSGDNIVIVAGVPVGSGGTNTMRVRTVK"
     gene            9511..10068
                     /gene="lepB"
                     /locus_tag="ACF4ZO_001693"
     CDS             9511..10068
                     /gene="lepB"
                     /locus_tag="ACF4ZO_001693"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HFD5487208.1"
                     /translation="MVKRDFIRNIILALLAIVIFILLGIFVFSTFEIHKEAENAYLKN
                     GDLVTIRRNIKPKYKDFVVYRVDDKDYVSRVIASAGQSATSMDDILYINNQVVDEPYI
                     EKTKNDFLTTSPMGSLFTEDFNITTISKGNNKVIPSGKYLLLNDNRQNKNDSREFGLI
                     DKSQIKGVITFKILPLDQFGFIENE"
BASE COUNT         3208 a         1657 c         2043 g         3176 t
ORIGIN      
        1 gtctccctct tcttttacga ataaataaat aggaggtgct ttatgctaac atacgacgaa
       61 tttaagcaag ctattgatga cggatatatc gtaggagaca cagttatgat cgtgcgcaag
      121 aacggacaga tttttgatta tgtgttgccg aatgagaaga taagagattg ggaggttgtg
      181 acagaggaga aggtggaaga agtgatggtg gaattagact atatcataat gaagaaaact
      241 ttgagtagac agaaaaataa ttgaagagtt gtcaatttag ttgtcaataa tatagaaagt
      301 tatggtaact catgaacaag acaaaaagaa aaaaccttga tgtaacaagg ttttagtaag
      361 ttatgattac ttacggtaag cattgatgga gccggtggga gtcgaaccca cgtccaaaca
      421 cctgccaaca tatttgtcta cgtccatagg ttatgtcttc atttaacaaa ctaaagacac
      481 ataactcaag ccattagttt gcgagtctat caatctcttg tcacgaaact agacaatttc
      541 gtaaccgtag cttgctattt tgagacttct aacaggacac aagcaatctt gtagaagtca
      601 cgctagctgg tttttaggca gctaaagcgt aagagtttgt attttttgca gttatattta
      661 actggcaatt tacatctgcc gatgggacgc aaaacatgcc tcataatgcc tgtcgaatcc
      721 gtaacaaccc caaatagata attaaccaat ttcttacact aactattcta tcaaaacttt
      781 ttttaaatag caaaatttta cagcttatgg tatgattagt ctatgacaaa acgtaattca
      841 aaagcctata tattatggca aaaaattatc aaaattttag gaattattgc attaattggt
      901 acttttttcc tcgctttttg gctgtataga ctaggtatat taaacgatag taatgctctt
      961 aaagacttag tgcagcgcta tagattatgg gggccgtttg tttttattgt cgtgcagatc
     1021 atacagattg tttttcctgt gattcctgga ggccttacga cagttgcagg ttttttaatc
     1081 tttggccctg taacaggttt tatttataat tatgtaggca tcattattgg cagtatagtc
     1141 ctcttcttgc ttgttaagac ttatggtcgt aaatttatct tactctttgt aaatgacaaa
     1201 acattttaca agtatgaaag gcgtttggag acaccaggat atgaaaaatt atttattttt
     1261 tgtatggcat cgcctgtttc tccagctgat attatggtta tgattacggg attgacggac
     1321 atgtctttaa agcgctttgt aactattctt ttaataacta aaccaatttc tattatcggc
     1381 tacagttatt tatttatttt tggaaaagat gttatatctt ggttcttaca gcattaaggt
     1441 ttggtgttaa tttgataaac cgcttctatt tgatggaaga cggtttttta atttactatg
     1501 aacactgaaa aaaactttct tttaaactat agtgtgtcat agtttaaaag aaagtcttaa
     1561 cgcttactgt aggttgagtt tatttttgat aataaaatta gtggcgaggt aaaacattat
     1621 catttcaata aattgttcca aaataagaag ataagttgtt ttttgctcag taaatgggaa
     1681 actatcggca cttgtattaa tattaaagat gtgattgtga acatatgttg cagcaacgct
     1741 aatcagaata actaatataa aatatgcaat aaaggccatc aagcctcgcc gattagaaaa
     1801 aagttgacct atagaaatgg aaagataaat taataagata ctcgtaaatg ttgataatag
     1861 gacataggct agtacagtta gcatattgat gaaataatcc atcttaaaac tattaaagaa
     1921 tccttctaat agttcgttga cgttaaacat tggtacaatt acaatagcga tagcaaatgc
     1981 aaggatgata gtattgaaaa cactgcaaat aaaagaagct agtagttttg ataaaataat
     2041 ttgatgcgaa ttgacgggta aagtcaacgt taagtatcct tcccgtccaa aaacactttt
     2101 gctaaaacgt ttgataatga taagtaatgt tgataagagg gagccagcga tcagggagcc
     2161 aaaagttaaa cctaatgtca gaggcaacat cttattggtt agtactccaa atagtccatc
     2221 actattgctt tgagcaaaca gttttatcgt aaatgacaaa atggcagcga tggcaataac
     2281 gaaagcatta agcgcaaagt accattttcc aatagatcta aattcgtatt ttaataattt
     2341 tccaaacatg atatcctcct aaaccttata agtttcccta aagagggaat caatggattg
     2401 ctggtattct tgtcttagat catcagcatt gccagataag aaaagtcttc cttgtttcaa
     2461 gaaaatgact tcgtcaagga taggttcaat gtccgaaatc aagtgggttg agataataac
     2521 agaagcattt tcacaataac tattaatgat ggtttttagg atgtagtctc ttgcggcagg
     2581 gtcaactcca ccaataggtt catcaagtac atagagtctg gctttacgac tcatcacaag
     2641 aattaattgt actttttctt tgtttccttt ggatagagtt ttgaagcggt cttcagggtc
     2701 tagttctaaa tctcttagaa ggcttgttgc tttggatttg tcaaagtcgc tgtaaaaatc
     2761 actaaagaac tccaacatgt ccttaattct catattttca ttgagataag tagtatctgg
     2821 taaataagaa ataatttttt ttgtctcaac acagggacgg tagccatcaa tgacaatttc
     2881 tcctttattt ggttgtaaaa ggccattaat gagtttaatt aaagttgttt taccacttcc
     2941 atttggacct aataatccga taattttacc gttcgggata gtaatggtta agtcatcaat
     3001 agcttttttt tcacggtaag attttgaaac atgatgtagt tgcaataggt gtgccattat
     3061 tgtgaatcct cctttaaaaa gctcgtcaaa acagggataa tctcagtgtg actaaatccc
     3121 atttttgtca tattggtgat aaatgattct aattcactaa ttgctaactc tcgtctttta
     3181 cgagcaatta atttttgatc gtcagtgaca aaacggccag cagtacgttg cgaataaacc
     3241 attccttccc gttcaagttc tgtaaacgct cgttgcatgg tgttaggatt gacacctgcg
     3301 atttctgcat attcacgaac agttggaagt tgatcaccac tcttgatttc ttggctaata
     3361 atttgcatca tgacatgttg tgctatctgc gcataaatag gagatttttc atcaaatttc
     3421 caagacattt ggtctccttt ctgagtaata tagatatttg tactaattaa atggtacaga
     3481 aaaaaaaggg gaatgtcaag ttttatgcca tttttcactc tttgagaagt agacgtagat
     3541 tagagagaaa attgaagcaa gaaaaccttt ttcatagtat aatagggaac aagataacca
     3601 aaggaggaac ttatgtttgc tcaacttgat actaaaactg tatactcatt tatggatagt
     3661 ttaattgact taaatcatta ttttgaacga gcaaagcaat ttggttacca caccatagga
     3721 atcatggata aggataatct ttatggtgct taccatttta ttaaaggttg tcaaaaaaat
     3781 ggactgcagc cagttttagg tttggaagta gagattctct atcaagagcg gcaggtgctc
     3841 cttaacttaa tcgcccagaa tacacaaggc tatcatcagc ttttaaaaat ttccacggca
     3901 aaaatgtctg gcaagcttca tatggattac ctctgccaac atttggaagg gatagcggtt
     3961 attattccta gtaaaggttg gagcgataca ttagtggtcc cttttgacta ctatatcggt
     4021 gttgatcagt atactgattt atctcatatg gattctaaga ggcagcttat acccctaagg
     4081 acagttcgtt attttgcgca agatgatatg gaaaccctgc acatgttgca tgccattcga
     4141 gataacctca gtctggcaga gacccctgtg gtagaaagtg atcaagagtt agcagattgt
     4201 caacaactaa ccaccttcta tcaaacacac tgccctcaag ctctacagaa tttagaagac
     4261 ttagtgtcag gaatctatta tgatttcgat acaaatttaa aattacctca ttttaataga
     4321 gataagtctg ccaagcaaga attgcaagag ttgactgagg ctggtttgaa ggaaaaagga
     4381 ttgtggaaag agccttatca atcgcgctta ctacatgaat tgatcattat ttctgacatg
     4441 ggctttgatg attatttttt gattgtgtgg gatttacttc gctttggacg cagtaaaggc
     4501 tattatatgg gtatgggacg tggctcggcg gcaggtagtc tagtggctta tgctctgaac
     4561 attacaggga tcgatccagt tcaacatgat ttgctatttg agcgcttttt aaacaaagaa
     4621 cgttatagca tgcctgatat tgatatcgat cttccagata tttaccgttc agaatttcta
     4681 cggtatgtcc gaaatcgtta tggtagcgac cattcggcgc aaattgtgac cttttcaacc
     4741 tttggcccta aacaggctat tcgtgatgtt ttcaaacggt tcggggttcc agaatacgaa
     4801 ctgaccaatc tcactaaaaa aattggtttt aaagatagct tggctactgt ctatgaaaag
     4861 tcaatctctt ttaggcaggt tattaatagt agaactgaat ttcaaaaggc ctttgctatt
     4921 gccaagcgta tcgaaggaaa tccaagacaa acgtccattc acgcagctgg tattgtgatg
     4981 agtgatgata ccttgaccaa tcatattcct ctaaaatcgg gcgatgacat gatgatcacc
     5041 cagtatgatg ctcatgcggt cgaagctaat ggcctgttaa aaatggattt tttggggtta
     5101 agaaatttga cctttgttca aaaaatgcaa gagaaggttg ctaaagacta cgggtgtcag
     5161 attgatattg cagccattga tttagaagac ccgcaaacgt tggcactttt tgctaaaggg
     5221 gataccaagg gaattttcca atttgaacaa aatggtgcta ttaatctttt aaaacggatt
     5281 aagccacaac gttttgaaga aattgttgcc actaccagtc taaatagacc aggggcaagt
     5341 gactatacca ctaatttcat taaacgaaga gaaggacaag aaaaaattga tttgattgat
     5401 cctgtgattg ctcccatttt agagccaact tacggtatta tgctttatca agaacaagtt
     5461 atgcagattg cacaggttta tgctggtttt acgttaggca aggccgactt gttaaggcgt
     5521 gccatgtcta aaaaaaatct acaagaaatg caaaaaatgg aagaagactt tattgcttct
     5581 gctaagcacc tagggagagc tgaagaaaca gctagaggac tttttaaacg gatggaaaaa
     5641 tttgcaggtt atggttttaa ccgcagccat gcctttgcct attcagcttt agcttttcaa
     5701 ttggcttatt tcaaagccca ttacccggct gttttttacg atatcatgat gaattattct
     5761 agcagtgact atatcacaga tgctctagaa tcagattttc aagtagcgca agttaccatt
     5821 aatagtattc cttacactga taaaattgaa gctagcaaga tttacatggg gctgaaaaat
     5881 attaaggggt tgccaaggga ttttgcttat tggattattg agcaaagacc atttaatagc
     5941 gtagaggatt ttctcactag aactccagaa aaatatcaaa aaaaggtttt ccttgagcct
     6001 ctgataaaaa taggtctgtt tgattgcttt gagcctaacc gtaaaaaaat tctggacaat
     6061 ttggatggtt tactggtatt tgttaatgag cttggttctc ttttttcaga ttcttccttt
     6121 agttgggtag atacgcaaga ttactcagca actgaaaaat attctttgga acaggaggtc
     6181 gttggagttg gcatgagcaa gcatccttta attgatattg ctgagaaaag tatccaaact
     6241 tttactccca tttcacagtt agtcaaagaa agcgaagcag tcgtactgat tcaaatagat
     6301 agcattagga tcattagaac caaaacaagt gggcagcaaa tggctttttt aagtgtgaat
     6361 gacactaaga aaaagctcga tgtcacactt tttccacaag agtatgccat ttataaagac
     6421 caattaaaag aaggagaatt ctattactta aaaggtagaa taaaagaaag agaccatcga
     6481 ctgcagatgg tgtgtcagca agtgcaaatg gctattagtc aaaaatattg gttattagtt
     6541 gaaaaccatc agtttgattc ccaaatttct gagattttag gtgcctttcc aggaacgact
     6601 ccagttgtta ttcactatca aaaaaataag gaaacaattg cattaactaa gattcaggtt
     6661 catgtaacag agaatttaaa ggaaaaactt cgtccttttg ttctgaaaac ggtttttcga
     6721 taaaaatgga caattagtga agtattttgc aaatgaatgt gctataataa gaccgttaaa
     6781 ttaattaaag gagtaccaga aaatgaaacg tattgctgtt ttaaccagtg gcggtgacgc
     6841 tcctggtatg aatgctgcta ttcgtgcagt cgttcgtaaa gcaatctcag aaggaatgga
     6901 agtttatggt atcaaccgtg gctatgcagg tatggttgat ggcgacattt tcccactggg
     6961 ttcaaaagaa gttggtgata aaatctcacg tggtggaact ttcttatact cagctcgtta
     7021 tccagagttt gctcaacttg aaggtcaatt ggctggtatt gagcaactta aaaaacatgg
     7081 tattgagggt gttgttgtta ttggtgggga tggttcttat catggcgcta tgcgcttgac
     7141 agagcacggc ttcccagcgg taggtatccc aggaacaatc gataacgata ttgcgggaac
     7201 tgactacact atcggatttg atacagcagt taacacagca gttgaagcta ttgataaact
     7261 tcgtgacacc tcatcaagtc acggacgtac ttttgtggtt gaagtgatgg gtcgcaatgc
     7321 gggtgatatt gctctttggg caggtattgc tagtggtgct gatcaaatca ttgttccaga
     7381 agaagagttt gatattgaaa aagtggcatc aacaatccaa tatgattttg aacacaaagg
     7441 taaaaatcac cacattatcg tcttagctga aggtgttatg agcggtgaag cttttgctca
     7501 aaaactgaaa gaagctggcg ataagagtga ccttcgtgtg acaaatcttg gccacattct
     7561 tcgtgggggt tcaccaactg ctcgtgaccg tgtcattgct tcttggatgg gttcacatgc
     7621 tgttgagcta cttaaagaag gcaaaggtgg tttggctgtt ggtattcaca atgaagaact
     7681 tgttgaaagc ccaatccttg gtactgcaga agaaggtgct ttgttcagct tgactgaaga
     7741 aggcaagatt attgttaata atccacacaa agctcgttta gactttgcag ctttgaaccg
     7801 ttcattgtca caataagttt agttaaaatt gttaaatcgt caattattga caaaaaaata
     7861 agggagtttc agagtaaaat gaataaacgc gtaaaaatcg ttgcaacact tggtcctgcg
     7921 gttgaaatcc gtggtggtaa aaaatacgga gaagatggct actgggctgg tcaacttgat
     7981 gttgaagaat ctgcaaaaaa aatcgctgaa ttaattgaag ctggtgcgaa tgttttccgt
     8041 ttcaatttct cacatggtga ccacaaagaa caaggtgacc gtatggcaac tgttcgcctt
     8101 gcagaagaaa ttgctcgtca aaaagttggt ttccttttgg atactaaagg tcctgaaatg
     8161 cgtacggaat tgtttgcaga tgatgctaaa gagtttagct atgttactgg agaaaaaatc
     8221 cgtgtagcga ctacacaagg tattcaatca actcgcgatg ttattgcttt gaacgttgct
     8281 ggtagccttg acatctacga tgaagtagaa gtaggtcata ctattcttat cgatgatggt
     8341 aaacttggtt tgaaagtgat cgacaaagat atcgcaacac gtcaatttat cgttgaagta
     8401 gaaaacgacg gtattattgc taaacaaaaa ggtgttaata tccctaacac taaaattcct
     8461 ttcccagcac ttgcggaacg cgacaatgct gatatccgtt ttggtcttga acaaggactt
     8521 aactttattg caatctcatt tgttcgtaca gccaaagacg ttgaggaagt tcgtgaaatc
     8581 tgtcgcgaaa ctggtaacga ccatgtgcaa ttatttgcta agattgaaaa ccaacaaggt
     8641 atcgataatc ttgatgaaat catcgaagct gctgatggta tcatgattgc acgtggcgac
     8701 atgggtatcg aagtaccatt tgaaatggtt ccagttttcc aaaaaatgat tatcactaaa
     8761 gtgaatgcag ctggtaaagc agttatcaca gcaacaaaca tgcttgaaac aatgactgaa
     8821 aaaccacgtg cgacacgttc tgaagtatct gacgtcttca atgctgttat cgatggtact
     8881 gatgcaacaa tgctttcagg agagtcagct aacggtaaat acccggttga atctgttcgt
     8941 acaatggcga ctattgatcg taatgcacaa actcttctta acgaatatgg tcgtttagat
     9001 tcatctgcct tcccacgtac caataaaaca gatgttattg cttcagctgt taaagatgcc
     9061 actcattcaa tggacatcaa acttgttgtg actattactg agacaggtaa tacagctcgt
     9121 gcgatttcta aattccgtcc agatgcggac atcttagctg taacatttga tgaaaaagta
     9181 caacgtgctt tgatgattaa ctggggtgtt attcctgttc ttgctgaaaa acctgcatct
     9241 actgatgaca tgtttgaagt agcagagcgt gttgctgtgg aggcaggctt agttcaatct
     9301 ggggataata ttgttattgt tgctggtgtt ccagtaggat caggcggaac aaacacaatg
     9361 cgcgttcgta ccgtaaaata atctcgtttc agccatgagt tttcatggct tttttattgt
     9421 cttcttaaaa atagttggta aacaatcagt ttttcaaact tttgttattc tggataacat
     9481 gctataatag aataaagatt aggagtagtc atggttaaaa gagattttat cagaaatatc
     9541 atattagctt tgttagctat cgttatcttt attctcttag gaatttttgt tttttctact
     9601 tttgaaattc ataaagaagc tgaaaatgca tatctaaaaa atggagattt agtaacgata
     9661 cgtagaaaca tcaagccaaa gtataaagat tttgttgtat atagggttga tgacaaagat
     9721 tatgtcagtc gtgtgattgc cagtgctggt caaagcgcta catccatgga tgatatttta
     9781 tatatcaata atcaagttgt tgatgaaccc tatattgaaa aaactaaaaa tgattttttg
     9841 acaacctctc caatggggtc attgtttact gaagatttta atatcacaac catttctaag
     9901 ggtaataata aagttattcc aagcggaaaa taccttttat taaatgataa tcgtcaaaat
     9961 aagaatgata gtcgtgagtt tggtttaatt gataagtcac agattaaggg tgttattacc
    10021 tttaaaattc tacctctaga tcaatttgga tttatagaaa atgagtagtc aattgactac
    10081 tcat
//
LOCUS       DAXMQE010000050        10006 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.050, whole genome shotgun sequence.
ACCESSION   DAXMQE010000050 DAXMQE010000000
VERSION     DAXMQE010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10006)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10006)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10006
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.050"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            <1..570
                     /locus_tag="ACF4ZO_001694"
     CDS             <1..570
                     /locus_tag="ACF4ZO_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HFD5487209.1"
                     /translation="WLVAGLIIPGSELLLKNVGVNPTRTGILEVVEKMGAQIVYEDMN
                     KKEQVTSIRVVYSHLKGTIISGGLIPRLIDELPIIALLATQAQGTTCIKDAQELRVKE
                     TDRIQVVTDTLNSMGANIKATADGMIIKGPTVLYGANTSTYGDHRIGMMTAIAALLVK
                     QGQVHLDKEEAIMTSYPTFFKDLERLCHD"
     gene            563..1054
                     /locus_tag="ACF4ZO_001695"
     CDS             563..1054
                     /locus_tag="ACF4ZO_001695"
                     /EC_number="2.7.1.71"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004765 - shikimate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HFD5487210.1"
                     /translation="MTKVLLGFMGVGKTTVSKHLSMHCKDMDAIIEAKIGMSIAAFFE
                     QHGEIAFRTIENQVLKDLLFANDNSVIVTGGGVVVLQENRQLLRKNHQHNILLVASFE
                     TLYQRLKHDKKSQRPLFLKYSKEAFYEFYQQRMVFYEGLSDLVIRVDHRTPEEVANII
                     EGY"
     gene            1262..2713
                     /locus_tag="ACF4ZO_001696"
     CDS             1262..2713
                     /locus_tag="ACF4ZO_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070726 - cell wall assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HFD5487211.1"
                     /translation="MTKYPMGGLSHHEELRYFYLLRNLSYLSENEKKEFAFLKSKLEI
                     GRAYAPSKQHYRKSKRQEPYFEDDYYNDYSPNDLLEDDDVNHDSSFVPYGLPIYPKED
                     RYLNKKTKLTARRPIDAPQPIDEDDAFLTESVARCALPRSQKRKHKKKGCMKWFFNIL
                     GLLLMTVLMGLGLMFAKGVFDISTNKANYKPAVSQAFDGQETQDGTNILVLGSDQRVT
                     QGSTDARTDTIMVVNVGNHAKKIKMVSFMRDTLINIPGYSYNDNSYDLKLNSAFNLGE
                     QEDHHGAEYVRRALKHNFDIDIKYYVMVDFETFAEAIDTLFPNGVKIDAKFATVGGVA
                     VDSVEVPDDLRMKNGVVPNQTIEVGEQRMDGRTLLNYARFRKDDEGDFGRTVRQQQVM
                     SAVMSQIKDPTKLFTGSAAIGKIYALTSTNVSFPFVVKNGVSVLGSGKNGVEHVTIPE
                     NGDWVDEYDMYGGQALYIDFDKYQKTLAKLGLR"
     gene            2795..4150
                     /gene="rlmD"
                     /locus_tag="ACF4ZO_001697"
     CDS             2795..4150
                     /gene="rlmD"
                     /locus_tag="ACF4ZO_001697"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HFD5487212.1"
                     /translation="MLKKNDIIQVAISDLSHEGAGVAKHDGFVFFVDNALPEEVIDMR
                     VLKVNKNSGFGKVEAYHYLSPARNADVNLTYLRTGIADLGHLTYEDQLTFKKKQVQDS
                     LYKIAGISDVTVESTIGMTEPLAYRNKAQVPVRRVNGQLETGFFRKHSHDLIPISDYY
                     IQDKEIDRLINFTRDLLRRFDIKPYDETEQTGLLRNIVVRRGHYSGEMMLVLVTTRPK
                     VFRVDQVIEKIVEAFPAVVSIIQNINDKNTNAIFGKDFKTLYGKDTITDSMLGNNYAI
                     SAQSFYQVNTVMAEKLYQTAIAFSDLSKDDIVIDAYSGIGTIGLSFAKTVKAVYGVEV
                     IEAAVRDAQHNAALNGITNAYFVADTAEHAMATWAKDGIKPSVILVDPPRKGLTESFI
                     QASVAMGPQKITYVSCNPATMARDIKRYQELGYKLAKVQPVDLFPQTHHVECVVLLIK
                     E"
     gene            4189..4955
                     /locus_tag="ACF4ZO_001698"
                     /pseudo
     CDS             4189..4955
                     /locus_tag="ACF4ZO_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003060407.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
     gene            5040..5441
                     /locus_tag="ACF4ZO_001699"
     CDS             5040..5441
                     /locus_tag="ACF4ZO_001699"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HFD5487213.1"
                     /translation="MSDLTQEMTLNVISIFDNYQIELAEKGHLILSTEVTETALNYYG
                     NAHGGYLFTLCDQVGGLVARTTGVESVTLQANANYLKAGHKGDKLMVEGRLVHGGRTT
                     QVVDVTIHNQTGALLTKTSLTMFVTGRRHNG"
     gene            complement(5546..7030)
                     /locus_tag="ACF4ZO_001700"
     CDS             complement(5546..7030)
                     /locus_tag="ACF4ZO_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HFD5487214.1"
                     /translation="MKTIAFDSNKYLNLQRDHILERISQFDGKLYMEFGGKMLEDYHA
                     ARVLPGYEPDNKIKLLKELKEQVEIVIAINANNIEHSKARGDLGISYDQEVFRLIDKF
                     NTLDIYVGSVVITQYNNQPAADAFRKQLEKNGIASYLHYPIKGYPTDINHIISSEGMG
                     KNDYIKTSRNLIVATAPGPGSGKLATCMSQMYHDQINGVKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLETYGKTAVNYNRDIEVFPVLNRTFERILSKSPYA
                     SPTDMGVNMVGFSIVNEEAAIEASKQEIIRRYYQTLVDFKAERVTESAVKKIELLMND
                     IGVTPDDRHVTVAAHQKAEQTGQPALALQLPNGQIVTGKTSELFGPTAAVIINAIKTL
                     AKIDKTTHLIEPEYVKPIQGLKVNHLGSHNPRLHSNEILIALAITAMTSEEANLAMKE
                     LGNLKGSEAHSTVILTEEDKNVLRKLGVNITFDPVYQHHKLYRK"
     gene            7404..8624
                     /locus_tag="ACF4ZO_001701"
     CDS             7404..8624
                     /locus_tag="ACF4ZO_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFD5487215.1"
                     /translation="MSTLSLDTTNKRALVAAIAASGTDDLNVMFLAFSMSSIMTDLGL
                     SGTQGGWIATITNLGMLVGGLLFGLLADRHHKFKVFKWTILLFSVATGLIYFTQSLPY
                     LYLMRFIAGIGVGGEYGVAIAIMAGIVPPEKMGRMSSLNGIAGQLGSISSALLAGWLA
                     PSLGWRGLFLFGLLPILLVIWMTLAIDDQKIWDHYGQEEEECSQPIKINELFKTKSLT
                     AQTLALMVMTTVQIAGYFGMMNWLPTIIQTSLNLSVKSSSLWMVATIVGMCLGMLCFG
                     QLLDCFGPRLIYSLFLLASSICVYLFQFANSMASMVIGGAIVGFFVNGMFAGYGAMIT
                     RLYPHHIRSTANNVILNVGRALGGFSSVAIGSILDASGISMVMIFLASLYVISFGAMW
                     TIGQLKAERYQQLR"
     gene            complement(8744..9109)
                     /locus_tag="ACF4ZO_001702"
     CDS             complement(8744..9109)
                     /locus_tag="ACF4ZO_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase family protein"
                     /protein_id="HFD5487216.1"
                     /translation="MTIYSHTYETRPNHSAKAMSSGTLNVLATPALVAFMENASYLFT
                     QEQLDSDFTTVGSEIAIQHLAASAIGDPVTIIITALKEEGRKYDFRLEAFVGEQLIGK
                     ACHTRVRVNSKHFMAKVAE"
     gene            9223..9954
                     /locus_tag="ACF4ZO_001703"
     CDS             9223..9954
                     /locus_tag="ACF4ZO_001703"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HFD5487217.1"
                     /translation="MRLDKFLVATGVGTRSQVKLLLKKKAIFVNQKVETSAKAHIDEY
                     KDLVTYQGTPLVYESFVYYLLNKPSGYVSATQDRQQATVMELLDDTARQKTVFPVGRL
                     DKDTRGLLLLTNNGQLAHDLLSPKKHVTKEYLAKVAGIMTEADKDYFARGISLKDHQC
                     LPAHLEVLASDLQQQTSLVKITIQEGKFHQVKRMVAACGKEVLDLQRLSMGPLKLDPS
                     LAEGEFRRLTPEELQSLAPYCQSSL"
BASE COUNT         2991 a         1801 c         2166 g         3048 t
ORIGIN      
        1 tggcttgtcg ccggcttaat tattcctggt tcggagctcc ttttaaagaa tgttggagtc
       61 aatccgacac gaacagggat tcttgaagtg gttgaaaaaa tgggagcaca gattgtctat
      121 gaagatatga ataagaaaga gcaagtaact agtattcgag tggtatattc tcacttgaaa
      181 ggaactatca tatcaggagg tcttatccct cgattgattg atgaactgcc catcattgca
      241 cttcttgcaa cccaagcaca aggaacaacc tgtattaaag atgctcaaga attacgagtc
      301 aaagaaacag atcgtattca agtagtaact gatactctta acagtatggg agctaatatc
      361 aaagcaacag cagatggcat gattatcaaa ggccctacgg tactatatgg ggctaacaca
      421 agtacctatg gagatcatcg tattggtatg atgacagcaa ttgcagcctt gcttgttaaa
      481 caaggacagg tccatttgga taaagaagaa gccatcatga cgtcttatcc gacgtttttc
      541 aaagatttag aaaggctgtg tcatgactaa agtgttattg ggatttatgg gagtggggaa
      601 aacaacggtt tcgaaacacc taagtatgca ctgtaaagat atggatgcta ttattgaagc
      661 taaaatcggt atgtctattg cagctttttt tgaacagcat ggagaaatag catttcgaac
      721 aattgaaaat caagtgttaa aagatctatt gtttgcaaat gataatagtg tcatcgtaac
      781 aggtggcggt gtagtggttt tacaagaaaa tcgacaatta ctgagaaaaa atcaccagca
      841 taatatttta ttggtagctt cttttgaaac tttgtaccag cgtttaaaac atgataaaaa
      901 gtctcaaaga cctctatttc ttaagtactc taaggaagca ttttatgaat tttatcaaca
      961 acgtatggta ttttatgaag gactttcaga tttagtaatc agagttgacc atcgtacgcc
     1021 tgaagaagtt gccaacatca ttgagggtta ttagcaggtc attgtcgtaa tctgatattt
     1081 atggttttaa acaggtatct gtctaaagca cttcttatgg caagttggct ttattaaata
     1141 ttaggaaata atcttgatta ttctataatg attaaaattt tgagaggaca atctggctaa
     1201 tataggttat aatggtagta ttcgttaaaa gtgcaattgt aatactaaga gatgataaga
     1261 tatgacaaaa taccccatgg gtggccttag tcaccatgaa gaattacgtt atttttatct
     1321 cctaaggaat ttgagttacc ttagtgagaa tgaaaaaaaa gagtttgctt ttttaaaatc
     1381 taaattggaa attggtcgag cttatgctcc ttctaagcag cattatagga agtcaaaacg
     1441 gcaagaacct tactttgaag atgactacta taacgactac tcaccaaatg atttactaga
     1501 agatgatgac gtcaatcatg actcctcttt tgttccatat ggtttaccga tatatcctaa
     1561 agaagacaga tatttaaaca aaaaaacaaa acttacagct cgtagaccta tagatgctcc
     1621 gcagcctatt gatgaagacg atgctttttt aacagagtct gttgctcgtt gtgctcttcc
     1681 tagatctcaa aaaagaaagc ataagaaaaa aggatgtatg aaatggtttt ttaacattct
     1741 tggcttattg ctaatgactg tgcttatggg gttagggttg atgtttgcaa aaggggtttt
     1801 tgatatttct actaataaag ctaattacaa accagctgtt tcccaagctt ttgatggtca
     1861 agaaactcaa gatggtacga acattctggt tttgggttct gaccaacgag ttactcaagg
     1921 ttctacagat gctcgcacag ataccattat ggttgtcaat gtcggcaacc atgctaaaaa
     1981 aataaaaatg gtctctttta tgcgtgacac tttgattaac attccaggat acagttataa
     2041 tgataattcg tatgatctta aattaaatag tgcatttaat cttggagagc aagaagatca
     2101 ccacggagca gagtacgttc gacgggcctt aaaacataat tttgatatcg acattaagta
     2161 ttatgtgatg gtagattttg aaacatttgc agaagctatt gacaccttgt ttccaaatgg
     2221 tgttaagatt gatgccaaat ttgcgacagt aggtggtgta gctgttgact ccgtagaagt
     2281 tccagatgac ctgcgaatga aaaatggggt tgttcccaac caaaccatcg aagttggaga
     2341 acaacgcatg gatggtagaa ccttgctcaa ctatgctcgt ttccgtaaag atgacgaagg
     2401 agatttcgga cgaaccgtcc ggcagcaaca ggttatgtca gctgttatgt cccaaatcaa
     2461 ggacccaact aaactcttta cagggtctgc ggctattggt aaaatctatg cgctgacttc
     2521 gaccaatgtt tcttttccat ttgttgttaa aaatggtgtt tctgttttag gaagtgggaa
     2581 aaatggagtt gagcacgtga ccatcccaga aaatggggat tgggttgacg aatacgatat
     2641 gtatggagga caagcccttt acatagattt tgataagtat cagaaaacgt tagccaaatt
     2701 aggtctgcgc taagatatgg tataatggag agtaactaaa gttgctcttc ttttttgagc
     2761 aatggttagc cctagaaaag gaaaaagaat aagaatgttg aaaaaaaatg atattatcca
     2821 agttgctatt tcagatttaa gccatgaggg agcaggtgtc gctaaacacg atggttttgt
     2881 tttctttgtt gataatgcct tgccagaaga agtgattgac atgcgtgtct taaaggtcaa
     2941 taaaaacagc ggttttggca aagtagaagc ctatcattac ctgtcgccag ctagaaatgc
     3001 agatgtcaat ttaacttatt tgcgaacagg cattgcagac cttggacatc taacttatga
     3061 agaccaactg actttcaaaa agaaacaagt tcaggacagc ctctataaaa ttgctggaat
     3121 cagtgacgtg acagtcgaaa gcacgattgg gatgacagaa cctttagctt accgaaataa
     3181 ggctcaagtt cctgttagac gtgttaatgg tcagctagaa acaggctttt tccgcaagca
     3241 ttctcatgac ttgattccta tttcggatta ttatattcag gacaaagaga ttgatcgtct
     3301 cattaatttt acccgtgatt tattacgccg ctttgatatt aaaccgtatg acgaaacaga
     3361 acaaacaggt ctcttgagaa atattgttgt tcgccgaggc cattactctg gagaaatgat
     3421 gctggtctta gtgactacac gcccaaaagt tttccgtgtt gaccaagtca ttgaaaaaat
     3481 cgttgaagct tttccagcag tggtgtctat tattcaaaat attaatgata agaacaccaa
     3541 tgcaatcttt ggtaaagatt tcaaaacgct ttacggcaag gataccatta ctgatagcat
     3601 gcttggaaac aactatgcca tttctgccca gtctttctac caagtgaata cggttatggc
     3661 agaaaaactc tatcaaacag ctatagcctt ttcagacctt tctaaagatg acattgtgat
     3721 tgacgcctac tcaggtatcg gaaccattgg cctatcattt gctaaaacag ttaaagctgt
     3781 ttatggtgtt gaagtgattg aagcagctgt tagagatgct caacacaatg ccgctcttaa
     3841 tggcatcacc aatgcctact ttgtcgcaga taccgcagaa catgccatgg caacatgggc
     3901 gaaagatggc attaaaccaa gtgttattct ggtagacccg ccacgaaaag gcttaacaga
     3961 aagtttcatc caagccagcg tggcaatggg accacaaaaa attacctacg tttcctgcaa
     4021 cccagccacc atggcgcgtg acatcaagcg ttatcaagag ttgggttaca aactggccaa
     4081 agtacagccc gtagatttgt ttccgcaaac gcatcacgtc gagtgcgtag tgttgctaat
     4141 caaggagtaa ggtagctgcc tccacatgac aaaaataagg agaaacgaat gcctattacc
     4201 aaacacgaga ttcccctttt agaatgtgat agtaatccat cagccgtcat tatacctaca
     4261 catgaaggtc tacagctaag tgtgtctatg ctttcttaga agacgagatt gaagcttttg
     4321 ctttagacca tcaaggtaaa aaagtagcag aattcatttc agccacaaag gtttaccctg
     4381 tttatcagat accttataaa ggccaagaca tttgcctagc tcaagctcct gcggcgcaat
     4441 tcatggactg gctgattggt tatggggtta aagaaatgat cagtacagga acctgtggcg
     4501 ttttggttcc tatcgcagaa aaccgttttt tagtgccagt taaggctttg cgagatgaag
     4561 gaacaagtta tcattacgtg gcaccatctc gttatattga tattgatcct aagatgctta
     4621 gactgattga gaaaacgctt ttagcacagg ggttagctta tcaagaggtc atcacctggt
     4681 caacagatgg tttttaccga aaaaccaaag aaaaagtggc ttatcgccag gaagaggggt
     4741 gttcggttgt tgagatggaa tgttctgcct tagcagcagt agctcaatta agaggcatcc
     4801 tttgggggca actcttattt acagcagata ctctagcaga tgtagaggtt tacgatcaac
     4861 gcaactgggg cgccgattcc tttagttttg cgctccattt atgcttggaa gtgctcaata
     4921 cgctagaaaa ggatggaaag gctactgatt tttgaaacat gagctctgcc ttctgttcct
     4981 atttgtagta taatgaggct tgtattgctt ttagactaag cttagaaaag agaaaaacaa
     5041 tgtcagattt aacacaagag atgaccttaa atgttattag tatttttgat aattaccaaa
     5101 ttgaacttgc tgaaaaagga caccttattt taagtactga agtgactgag acggctttga
     5161 attattatgg gaatgctcat ggtggttatc ttttcaccct atgtgatcaa gtaggtggtt
     5221 tagttgctag aactactggc gtagaatctg tcaccttaca ggccaatgct aactatttaa
     5281 aagcagggca caagggagac aagctgatgg ttgaaggtcg attggttcat ggaggtcgaa
     5341 ccacgcaggt ggttgatgtg acgattcata accaaacagg agctcttcta acaaaaacaa
     5401 gcttgaccat gtttgtgact ggccgacgtc ataacggatg attaatgaat caataaagga
     5461 aaaaagtccc aactctctga gaattgggac ttttttcctt tattgagaga taccataaat
     5521 cacccgttag acgggtggtt atggtttatt tacggtaaag tttgtgatgt tggtaaacag
     5581 ggtcaaaggt aatatttacc ccaagttttc ggagtacatt tttatcttct tcggttaaga
     5641 taacggtaga atgggcttca ctacctttca aattgccgag ttctttcatg gctagattag
     5701 cttcttcact agtcatagca gtaatggcta acgcaatcag aatttcattg gaatgaagcc
     5761 gcggattgtg actgcctaag tggttcactt tgagcccttg aataggtttt acgtattcgg
     5821 gttcaatcaa atgagtggtt ttatcaatct ttgccaaggt tttaatcgca ttgatgataa
     5881 cagctgcagt tggtccaaag agttcagatg ttttacctgt cacaatctgc ccatttggta
     5941 gttggagagc aagggcaggt tggcctgttt gctctgcttt ttgatgagca gctacagtaa
     6001 cgtgacgatc gtcaggggtg acaccgatat cattcatcaa gagctcaatt tttttgacag
     6061 cagattctgt gacccgctct gccttaaaat ccacgagggt ttggtaataa cgacggatga
     6121 tttcttgttt agaagcttcg atagcagctt cttcattgac gatagaaaaa ccaaccatgt
     6181 taacacccat atcggttggt gaggcataag gagacttgct caaaatacgc tcgaaggtcc
     6241 gatttaagac aggaaagacc tcgatatcac ggttgtaatt aacggccgtt ttgccataag
     6301 tttccaaatg gaaggggtca atcatattca catcatctag gtctgccgtg gctgcctcat
     6361 aagccagatt gacagggtga tgaagaggaa gattccaaac tggaaaggtt tcaaatttag
     6421 catagccaga cttaacccca ttgatttggt cgtgatacat ttgggacatg caagtggcta
     6481 attttccaga cccagggcct ggtgctgtag caacgataag gttacgactc gttttgatgt
     6541 aatcattttt ccccatcccc tcagatgaga taatatgatt aatatctgtc gggtagccct
     6601 tgataggata atgcaggtaa gaagcaatgc catttttttc gagttgcttg cgaaaggcat
     6661 ctgcagcggg ttggttattg tattgggtaa taacgacaga acctacgtaa atatctaacg
     6721 tgttaaattt gtcaattaag cgaaagactt cttggtcata agaaatgcct aaatcaccac
     6781 gcgctttaga atgttcaata ttattagcgt taatggcaat tacaatttcg acttgttctt
     6841 tgagctcttt gagtaattta atcttattgt caggttcata gccaggaagt acacgggcag
     6901 catggtaatc ttctaacatt ttaccaccaa attccatgta aagtttgcca tcaaattggc
     6961 tgatacgttc taaaatatga tctctttgca agtttaaata cttgttagaa tcaaaagcaa
     7021 tagtcttcat tttttcacct ctgtaaagca ttataacaaa gaaattccaa gaaagaaaag
     7081 gttttttgca gggatacctc attttgtgac tttttaaaaa aacttaggct tggttcttag
     7141 aataaaaatg tatctgctat gttcaaaaga acttgacaat taaaatgagc tttactatac
     7201 tagtaacaat taaatactac tttaaacatg ttccgtgaag catgaaagtc ttaacagtaa
     7261 agagagtttt tttgtcatct cttattattt agtgaacttt gatggacttg cggacttgtt
     7321 tccaagtctt tttttgacct ttggacaaag ggtattcaat taattaaggt agtcagtgag
     7381 ctactattaa gaaggagaca attatgtcaa cattatcatt ggacaccaca aataagcgag
     7441 ctttagtggc agctattgca gcttcaggaa cggatgactt gaatgtcatg tttcttgcct
     7501 tttccatgtc ttccattatg acagacttgg gtcttagtgg cactcagggt ggctggattg
     7561 cgaccattac caatttagga atgttggtgg gaggcctctt attcgggttg ctggctgata
     7621 ggcaccacaa gtttaaggtc tttaaatgga cgattttact gttttcagta gcaacaggat
     7681 taatttattt tactcagtct ttgccctact tgtacctgat gcgatttatt gctggcatag
     7741 gagttggagg tgaatacggt gtagccattg ccataatggc agggattgta ccaccagaaa
     7801 aaatgggtcg gatgtcttct ttaaatggta ttgctggcca gcttggctcc attagttcgg
     7861 ctcttttagc agggtggctg gctccaagtc taggctggcg tggcctcttt ctctttggat
     7921 tacttccgat tcttttggtg atttggatga ctttagccat agatgaccaa aaaatttggg
     7981 atcattatgg gcaagaagag gaagaatgca gtcaaccaat taaaatcaat gaactattca
     8041 aaacaaaatc cttaacagct caaacccttg ctttaatggt catgacgact gtgcagattg
     8101 cgggctattt tggaatgatg aattggttgc caactattat tcaaacaagc ttaaaccttt
     8161 cagtaaaaag ttcgtccttg tggatggtgg ctactattgt cggcatgtgt ttggggatgc
     8221 tgtgttttgg tcagctttta gattgctttg gtccacgtct gatttattcc ctctttttat
     8281 tagcatcatc tatttgtgtt tacctttttc aatttgccaa ttccatggcg agtatggtta
     8341 ttggaggtgc tattgtcggt ttttttgtca atgggatgtt tgctggctac ggggctatga
     8401 ttaccagact ttatccccat cacattcgat ccacggctaa taatgttatt ttgaatgttg
     8461 gccgtgctct aggaggattt tcgtccgttg ctattggtag tattttagat gcctcaggta
     8521 tttcaatggt catgattttc ctagcttctc tgtacgtgat tagttttgga gccatgtgga
     8581 ctattggtca gttaaaagca gaacgctacc aacaattgcg ttagcaaaga gatgggtgtt
     8641 agtatttgag ttactttcac tcacaaagct attttattga ttgagataag caaaaaggta
     8701 agcacttagg gattgcttac ctttttggtt cttttctttt gttttactcc gctactttgg
     8761 ccataaaatg tttactgttc accctaactc tagtatgaca ggcttttcca atgagttgtt
     8821 ctcccacaaa agcttccaag cggaaatcgt attttcggcc ttcttcttta agggctgtaa
     8881 tgatgattgt aacaggatct ccaatggctg aagctgccaa atgttggata gctatctcgc
     8941 tgccaaccgt tgtaaagtca ctgtcgagct gttcttgggt aaataagtaa gaagcatttt
     9001 ccataaaagc aacaagagca ggagtagcta ggacattcag cgttcctgag ctcatggctt
     9061 tagccgaatg attgggacgg gtttcataag tgtgagaata aatagtcata agttaatctc
     9121 ctcgtttcta taagcctatt ataatatatt aagcgcttac agtcatgaaa ccactgtttt
     9181 ttatgttata cttaataatg aattttcttt gaaagggtta tgatgcgttt agataaattt
     9241 ttagtggcaa ctggtgttgg aactaggagc caagtcaaac ttctcttaaa aaagaaggct
     9301 atcttcgtca atcaaaaggt tgaaacctct gccaaagcac acattgatga atacaaggat
     9361 ttggtgacgt atcaaggcac gcccttggtc tatgaatcct ttgtttatta cctgttaaac
     9421 aagccgtcag ggtatgtgtc ggcaacccag gacagacagc aggctactgt tatggagttg
     9481 ttagatgaca cggctaggca aaaaacagtt tttcctgtgg gtaggttaga taaggatacc
     9541 cgtggacttt tgctcttgac caataatgga caactagccc atgacctttt atcccctaaa
     9601 aaacatgtta cgaaagagta cttggctaaa gtagcaggca tcatgactga agctgataaa
     9661 gattattttg ctagaggtat ttccttaaag gatcaccagt gcctacctgc tcatttagaa
     9721 gtgcttgcta gtgatttaca gcagcaaaca agtttggtta aaattaccat acaagaagga
     9781 aaattccatc aggtgaaacg catggtagca gcctgtggaa aggaagtgct tgacttgcag
     9841 cgtctcagca tgggaccatt aaaactagac cctagccttg cagaagggga gtttaggcgc
     9901 ctgacgcctg aggaattgca gagcctggca ccttattgtc agagctcact ataaaaagaa
     9961 acctccccgg tcagtacact tgctcaatag ttgcgaaatg agcatc
//
LOCUS       DAXMQE010000051         9575 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.051, whole genome shotgun sequence.
ACCESSION   DAXMQE010000051 DAXMQE010000000
VERSION     DAXMQE010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9575)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9575)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9575
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.051"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            <1..871
                     /locus_tag="ACF4ZO_001704"
     CDS             <1..871
                     /locus_tag="ACF4ZO_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HFD5487218.1"
                     /translation="GEAGHIKVTAKVSQQLSSVFQTQVACRAPKEHLVTLPLEKYQFK
                     KSRLTSQQEIGQSCLKTTQFLSVLENKDTQQKAGKVSTPHILITSYQHYLPLPLQVCS
                     QAFDFKKGDDIFLPQWLQVKDAQGSFVKKAFPMTWYLKEKIFAKPILVTGYVSCFGQS
                     IPVEARLNLAQASKRRHQDLSLVAKQSLAASQKRLTYCYQYDTVQAIGAISLQNHTGT
                     SLSVSVAISYGSQSSIKQETLMLADSHLSQLEEVIFFDDILTVLYLAVTLEVIEGPDL
                     TEDSIQIGLWDLA"
     gene            1009..1887
                     /locus_tag="ACF4ZO_001705"
     CDS             1009..1887
                     /locus_tag="ACF4ZO_001705"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020905350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004764 - shikimate 3-dehydrogenase
                     (NADP+) activity [Evidence IEA];
                     GO_process: GO:0019632 - shikimate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HFD5487219.1"
                     /translation="MSERLSGHTLLVSLLATPIRHSLSPKMHNEAYAKLGLDYAYLAF
                     EVGTEQLADAVQGIRALGIRGSNVSMPNKEAILPLLDDLSPAAELVGAVNTVVNKDGK
                     GHLVGHITDGIGALRALADEGVSVKNKIITLAGVGGAGKAIAVQLAFDGAKEIRLFNR
                     QATRLSSVQKLVTKLNQLTRTKVTLQDLEDQTAFKEAIRESHLFIDATSVGMKPLENL
                     SLITDPELIRPDLVVFDIVYSPAETKLLAFARQHGAQKVINGLGMVLYQGAEAFKLIT
                     GQDMPVDAIKPLLGDK"
     gene            2139..2894
                     /locus_tag="ACF4ZO_001706"
     CDS             2139..2894
                     /locus_tag="ACF4ZO_001706"
                     /EC_number="2.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFD5487220.1"
                     /translation="MVTKEVGHDFLARLGKKRLRPGGVEATNWLIEQGQFSQDCHVLE
                     VACNRCTTAIELAKTFGCQIDAVDLNPKVVKEAQERVAVEGLTRHITVSQANALSLPF
                     PDNHFDIVINEAMLTMLNAQAKEKALNEYWRVLKPGGRLLTHDVAYEDPKTRQVLDEL
                     RQTIHVNVAPLSLTGWQALYQEHGFSQVTYHHGKMSLMTPRGMIKDEGLMNTLNIMRR
                     GLKKENRQQFLKMRRFFTRTGKNLCYIAVKSVK"
     gene            2947..3285
                     /locus_tag="ACF4ZO_001707"
     CDS             2947..3285
                     /locus_tag="ACF4ZO_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HFD5487221.1"
                     /translation="MSYINNIEHAKVLDLTQEVMIEQDQMLSRTLVQRQDLGITVFSL
                     DKGQEIGRHSSPGDAMVTILSGLAEITIDQETYRVAEGQTIVMPAGIPHALYAVEAFQ
                     MLLVVVKPEA"
     gene            3287..3592
                     /locus_tag="ACF4ZO_001708"
     CDS             3287..3592
                     /locus_tag="ACF4ZO_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HFD5487222.1"
                     /translation="MIENLSQLVQYHDHQVASRSLSRLLGLSQSIVLYAMAQGESISQ
                     ETSPRDKVILVLEGQLIFDLEDQKQVLTQESLIAIPAQKVHHLEAKTDCKLLQVLLD"
     gene            complement(4028..5101)
                     /gene="aroB"
                     /locus_tag="ACF4ZO_001709"
     CDS             complement(4028..5101)
                     /gene="aroB"
                     /locus_tag="ACF4ZO_001709"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003856 - 3-dehydroquinate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HFD5487223.1"
                     /translation="MPQTLHVHSRVKDYDILFTDHVLKTLADCLGERKQRKLLFITDQ
                     TVYHLYQTLFEEFAQQYNAFVHVCPPGGQSKSLERVSAIYDQLIAENFSKKDMIITIG
                     GGVVGDLGGFVAATYYRGIPYIQIPTTLLSQVDSSIGGKVGVHFKGLTNMIGSIYPPE
                     AIIISTIFLETLPQREFSCGISEMLKIGFIHDKPLFQQLRDFQKETDKQGLERLIYQS
                     ISNKKRIVEQDEFENGLRMSLNFGHTLGHAIESLCHHDFYHHGEAIAIGMVVDAKLAV
                     SKGLLPKEDLDSLLQVFERYQLPTSLERADVSATSLFDVFKTDKKNSEQHIIFILPTE
                     TGFTTLAINKDDHQFVEKLDSLL"
     gene            complement(5157..5909)
                     /locus_tag="ACF4ZO_001710"
     CDS             complement(5157..5909)
                     /locus_tag="ACF4ZO_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0046417 - chorismate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 3-deoxy-7-phosphoheptulonate
                     synthase/chorismate mutase"
                     /protein_id="HFD5487224.1"
                     /translation="MIDIMSDFQNKTCSKNNFIVGPCSIESYDHIRLAASSAKKLGYN
                     YFRGGAYKPRTSAASFQGLGLQGIRYLHEVCQEFGLLSVSEIMSERQLEEAYDYLDVI
                     QVGARNMQNFEFLKTLSHIDKPILFKRGLMATIEEYLGALSYLQDTGKSNIILCERGV
                     RGYDVETRNMLDIMAVPIIQQKTDLPIIVDVSHSTGRRDLLLPAAKIAKAVGANGIMM
                     EVHPDPDHALSDAAQQIDYKQLEQLGQELWQD"
     gene            complement(6150..6220)
                     /locus_tag="ACF4ZO_001711"
     tRNA            complement(6150..6220)
                     /locus_tag="ACF4ZO_001711"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6186..6188),aa:Thr,seq:ggt)
     gene            6387..6641
                     /locus_tag="ACF4ZO_001712"
     CDS             6387..6641
                     /locus_tag="ACF4ZO_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HFD5487225.1"
                     /translation="MSYEKEFLKDFEDWVKTQIQVNQLAMATSQEVAQEDGDERAKDA
                     FIRYESKLDAYEFLLGKFDNYKNGKAFHDIPDELFGARHY"
     gene            6662..6958
                     /locus_tag="ACF4ZO_001713"
                     /pseudo
     CDS             6662..6958
                     /locus_tag="ACF4ZO_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635594.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
     gene            7332..7574
                     /locus_tag="ACF4ZO_001714"
                     /pseudo
     CDS             7332..7574
                     /locus_tag="ACF4ZO_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044523.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            7571..8134
                     /locus_tag="ACF4ZO_001715"
     CDS             7571..8134
                     /locus_tag="ACF4ZO_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HFD5487226.1"
                     /translation="MNLIIIGAQASGKMTIGQEVTRQTGMTLFHNHDSIDFVLRFMPW
                     SQESTALIERIRFAFFETFAKTGQDMIFTIVIDFNDPNDVAMLEKIQAVFQSYDQEVL
                     FVELKTDIEERLKRNRTENRLKHKPLKRNIEWSEQDIQSTMAYAVFNPEEPPKTLTHY
                     QKINNTHLTAAETAQLIIQKMTHIKEN"
     gene            8136..>9575
                     /locus_tag="ACF4ZO_001716"
     CDS             8136..>9575
                     /locus_tag="ACF4ZO_001716"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004832 - valine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006438 - valyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HFD5487227.1"
                     /translation="MTELSPKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIPP
                     PNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLREQGI
                     SRYDLGRDKFLDKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVFV
                     DLYKKGWIYRGEFIINWDPAARTALSDIEVVHKDVEGAFYHMNYMLEDGSRALQVATT
                     RPETMFGDVAVAVNPEDPRYKDLIGKHVLLPIVNKLIPIVGDEHADPEFGTGVVKITP
                     AHDPNDFEVGQRHNLPQVNVMNDDGTMNELAGDFAGMDRFEARQATVAKLEELGALVN
                     IEKRVHSVGHSERSGAVVEPRLSTQWFVKMDELAKQAMDNQETDDRVDFYPPRFNDTF
                     LQWMENVHDWVISRQLWWGHQIPAWYNAEGEIYVGEEAPEGDGWTQDEDVLDTWFSSA
                     LWPFSTMGWPDTDSEDFKRYFPTSTLVTGY"
BASE COUNT         2969 a         1887 c         2070 g         2649 t
ORIGIN      
        1 tggagaggcg ggacacatta aggtcacggc aaaagtctcg cagcaactta gcagtgtttt
       61 tcagacacaa gtagcctgcc gtgcccccaa agaacactta gtgacactac ctttagagaa
      121 atatcagttt aaaaagagcc gactgacaag tcaacaagaa attggtcaat cttgtctaaa
      181 gaccacacaa ttcctttctg ttttggagaa caaagacacc cagcaaaaag caggtaaggt
      241 tagcacacct cacattctta tcaccagtta ccagcactat ttacctctgc ccttgcaggt
      301 ttgttctcag gcatttgatt ttaaaaaagg cgatgatatc ttcttgcctc agtggctcca
      361 agtcaaagat gcccaaggtt cttttgtgaa aaaagctttt ccaatgacat ggtacctaaa
      421 agagaaaatc tttgccaagc ctattcttgt cacgggctat gtttcttgtt ttgggcaatc
      481 aataccggtt gaggcaaggc taaacctagc acaagctagc aaaagacggc accaggatct
      541 cagtttagtc gccaagcaat ccctggccgc aagtcaaaaa aggctaactt attgctacca
      601 atatgatacg gtgcaagcca taggagccat tagcttgcaa aatcacacag gcacatctct
      661 tagtgtttct gtggcaatca gttatggtag tcagagctct attaagcaag aaaccttgat
      721 gctagctgat agccacttga gccagttaga agaggttatt ttcttcgatg atattttgac
      781 tgttttgtat ctggcagtga cccttgaagt cattgaagga cctgacctaa ctgaagacag
      841 tattcaaatt ggcctttggg atttagcatg aagcatgagt aaaagaagac ttctttggca
      901 ccaggtctga tgaattctgt aaaataaggt ataataaaaa acaaataggc gtcctttatt
      961 acgtgaaagg tgcctttaca aggttgaaat ggaaagtgag atttctaaat gtcagaacgt
     1021 ttatcaggcc acaccctgtt ggtctctttg cttgctaccc ctattcgtca tagtttgtct
     1081 cccaaaatgc acaatgaagc ctatgctaaa ctggggctgg attatgccta ccttgctttt
     1141 gaagtaggga cagagcaatt agcagatgcc gtgcaaggga ttcgtgcctt aggaattcgt
     1201 ggctccaatg tgtctatgcc aaataaagaa gctattttac ccttattgga tgacttgtcc
     1261 ccagctgctg agttggtcgg tgcagtcaat acggttgtca ataaggatgg taaaggacat
     1321 ctcgtggggc atattacaga cggtatagga gcgctcagag ccttggctga cgaaggagtg
     1381 tcggtaaaga acaaaatcat taccctagca ggagttggtg gggctgggaa agctatcgct
     1441 gtccagctcg cttttgacgg cgccaaagag attcgtttgt ttaaccgaca agctacacgt
     1501 ctaagtagcg ttcaaaagct tgtgacaaaa ctgaaccagc taacaaggac taaagtaacc
     1561 cttcaagact tggaagatca gactgccttt aaggaggcca tcagggaatc tcatctattt
     1621 attgatgcta caagtgtagg aatgaagcct ttagaaaatc taagtttgat taccgacccc
     1681 gagctcattc gcccagactt ggtagtcttt gacatcgtgt acagcccagc agaaaccaag
     1741 ttactagcct ttgcccgtca acatggcgcc caaaaagtca ttaatgggct agggatggtg
     1801 ctttatcaag gagcagaagc ttttaaatta atcactggtc aagacatgcc agttgacgct
     1861 attaaacctc ttttaggtga taagtaactc aacccttttt aaagaacttt ttaagtaagc
     1921 ttaattatga tatattaata agagatggag cagtcatcat gggctgctaa aattcttttt
     1981 gcgagagctg tttttaagag caaaaagctt atttgaagag ccttatccct aacgtgatac
     2041 aagtcatagt tcctttgagg tctgccagat aacctaccgt ttttttagaa aagaagctct
     2101 tataaaagga aaagttcaat gaataaagga gaatagcaat ggtaacaaag gaagttgggc
     2161 atgacttttt agcacgtcta ggaaaaaaac gcttaagacc tggcggtgtt gaggcgacaa
     2221 actggttgat tgaacaagga caattctctc aggattgtca cgttttagag gttgcctgca
     2281 atcgctgcac gacagcaata gagttagcca aaaccttcgg ttgtcagatt gatgccgttg
     2341 acttaaaccc caaggttgtc aaagaagcac aagaaagggt tgctgttgag gggttaaccc
     2401 gtcacattac agtatcccaa gccaatgctt tatcactacc atttccagat aaccattttg
     2461 atattgtgat taatgaagcc atgttaacca tgttgaacgc ccaagccaag gagaaggcac
     2521 tcaatgaata ttggcgtgtg ttaaaaccag gcgggcgact tttgacacat gacgtagctt
     2581 atgaagatcc aaaaacaaga caagtacttg acgagttacg tcaaacgatt catgtcaatg
     2641 ttgctccctt gtcactaaca ggttggcaag ccttatatca agaacacggt ttttctcaag
     2701 tgacttatca ccatgggaaa atgtctttga tgacacctcg tggaatgatt aaggatgaag
     2761 gtcttatgaa caccctgaac attatgagac gaggccttaa gaaagagaac agacaacagt
     2821 ttttaaagat gcgtcgtttt tttaccagaa caggcaaaaa tctctgctat attgctgtaa
     2881 aaagtgtaaa ataaacctta gaccaacctg tccatacaac taaacagacc atagaggagt
     2941 tcgaagatgt cttatatcaa taatattgag cacgcgaagg ttcttgattt gacgcaagaa
     3001 gtaatgattg agcaagatca aatgttaagt agaacactag tccaaagaca agacctagga
     3061 ataacagttt tttctttaga taagggccaa gaaattgggc gacactcatc accaggagat
     3121 gccatggtta ctatcttaag tggcttagca gaaatcacca ttgatcaaga gacctaccgg
     3181 gttgctgaag gtcaaaccat tgtgatgcca gctgggattc ctcatgcctt atatgcagta
     3241 gaagcctttc aaatgctttt agtagtagta aaaccggagg cttaacatga ttgaaaatct
     3301 ctctcaattg gtgcaatatc atgatcatca ggtggctagc cgatccttga gccgtctact
     3361 gggattatct caatctattg ttttatatgc catggcccaa ggagaaagca ttagtcaaga
     3421 gactagtcca agagataaag taatacttgt tttagaaggt cagctcattt tcgatttaga
     3481 ggatcaaaaa caggtcctaa ctcaagaaag tcttatagcc atacctgccc aaaaagtcca
     3541 tcatttagaa gctaaaaccg attgtaaact attacaagtg cttttagatt aagggcttat
     3601 tgtcaactgt attgggtggc ctatggaaaa gcaaaagaga aggtgacgct catcttctct
     3661 ttttacgtat tcaaagcgat gacaatacga attttaaagc ttggctttct catctccaga
     3721 ttaagccctt tagcttggtt tattttagaa ttcactaaaa aaaccttaat gagtttccta
     3781 tctccttata ggtttctcat taaggctttt tagacgaaat aattgaacga caggcaaaag
     3841 aaagatcttt ttacgagtga taccgttctc ctatagttcc ataaatcctc tttttgatgt
     3901 tgctgttagt tattcttagc taaaagttat attgttatca agacttgtct tgtagtaaca
     3961 tgttttagga gttccaggat accgttattc tcttagcaag cttaactagc tagagtggag
     4021 tcactattta taataaactg tcgagcttct cgacaaattg gtgatcgtct ttgttaatgg
     4081 ctagggtggt aaaaccggtt tctgtgggta atataaagat aatatgttgc tcagaattct
     4141 tcttatctgt tttaaagacg tcaaaaaggg atgtcgcaga gacatcagct ctttcaagtg
     4201 atgttggtaa ctggtaacgt tcaaaaactt gaagaaggct atccaagtcc tcttttggca
     4261 agagtccttt ggaaacagcc agtttagcat caaccaccat accgatagca atggcttcac
     4321 cgtgatggta aaaatcatgg tgacagagcg attcaatcgc gtggcccaag gtatgcccaa
     4381 aatttaaaga catgcgcaaa ccattttcaa attcatcttg ttcaacaatc cgttttttat
     4441 tggaaatgga ttggtaaatc agacgttcaa gtccctgctt atcggtttct ttttgaaaat
     4501 cacgtaactg ctgaaaaagc ggtttatcat gaatgaagcc gattttgagc atctcactga
     4561 tgccgcagga gaattcccgt tgcggtaagg tctccaaaaa gatggttgaa ataatgatag
     4621 cctctggagg gtaaatgctg ccaatcatat tggttagacc tttaaaatgg actccaactt
     4681 tgcccccgat actgctatcc acctgactaa gtaaagtcgt tgggatttga atgtagggaa
     4741 taccacggta ataggttgca gcgacaaaac cacccagatc cccaacaaca ccaccaccaa
     4801 tagtaataat catatctttt ttggaaaaat tttcagcgat gagctggtcg tagatagcac
     4861 tgacacgttc caaggatttg gattgacctc ccggggggca gacatggaca aaagcgttgt
     4921 attgctgagc aaattcttca aagagagtct gatacaagtg gtagaccgtt tgatcggtga
     4981 taaacaagag tttacgctgt ttgcgctcac caaggcaatc tgctaaggtt tttaaaacat
     5041 ggtcggtaaa caggatatca taatccttga cccgagaatg gacatgaagt gtttgtggca
     5101 taagcactcc tttcatcagt actaggtaac agagataacg cagtgatatt tagagcttaa
     5161 tcttgccaaa gttcctgccc caactgttct aattgcttat aatcaatttg ctgggcagca
     5221 tctgacagcg catggtcggg atcaggatga acctccatca tgatgccatt ggcaccgaca
     5281 gccttcgcta tcttagcagc aggtaagagt aaatctcgtc tgcctgtcga atgagacacg
     5341 tccacaataa tcggtaaatc tgtcttttgt tgaataatag ggactgccat aatatcaagc
     5401 atatttctag tctccacatc gtagccacga acgccacgtt cgcataagat aatgttagat
     5461 tttccagtgt cttgtaagta ggaaagggcg cccaaatatt cctcgatagt agccatcaag
     5521 cctcgtttaa acaaaatagg cttatcgatg tgtgacaagg tttttaaaaa ttcaaaattt
     5581 tgcatgttgc gggcaccaac ctgaatgaca tcgagatagt cataggcttc ttctaattgg
     5641 cgctcggaca tgatttcact gaccgatagt aagccaaatt cctgacaaac ctcatgcaag
     5701 taacgaattc cttgcaggcc aaggccttga aaagaagcag cagatgttct tggtttatag
     5761 gcgcctcctc taaaatagtt gtaaccaagt tttttggcac ttgaagctgc taatctaatg
     5821 tgatcataag attcaatgga acaaggtcca acaataaaat tattcttaga acaagtctta
     5881 ttttgaaagt cagacataat gtcaatcatt cgtttgattc ctttactaat tctgtatggc
     5941 gtgctctatg ggataacgtc ttatttagga atacaaaatc tcgttgttat ccatgaagca
     6001 cccttagcct gtgaaatgat accataaaca agatgaaata gcaagtaaac cctagattgt
     6061 ctatgttctt agtcattttt attaaaaaag gcttgctagc tataaaaaaa tactgcccca
     6121 aatcttatta ggacagtatt ttttatagat gccaccaccg agaatcgaac tcggaacgaa
     6181 gcattaccat tgctttatta taccatttaa ctacagcggc tacctttcta taatactata
     6241 agttattaat tgatgcaagc ttttcttaaa aatatttcct taattgttta tcatcaaaat
     6301 gagagtacca gttattaata acatggcaca agaggcctgc cttatggtat aatggtaaag
     6361 atgatttcag aaagaggaag ctaagcatgt cttatgaaaa agaattttta aaagattttg
     6421 aagactgggt taaaactcag attcaagtca atcagctagc catggcaacc agtcaagaag
     6481 ttgcccaaga agatggcgat gaaagggcta aagatgcctt tattcgttat gaaagtaagt
     6541 tagacgccta cgaattttta ctaggtaaat ttgacaatta taaaaatggt aaagcctttc
     6601 acgatattcc agatgagtta tttggagcaa ggcattatta aggacaagga gacacgaaat
     6661 agtggcaaaa caaaaaaatc gtaaaaaagc attgaagtta gaaatgaagc gtaatggctt
     6721 gttaaaaaaa gcaggtcaag tttttgataa ggcagttgaa agtgttgaaa cagccgtgga
     6781 taaaaccatt tctgctggta aaaatcttgt ggaaaaaggc agccaaacgg ttgaaaacct
     6841 gacagcaagc aaggaaagac ttactcttga tgagtttgca gggcagccag ttgtagctgg
     6901 tatccgctct gaccttgtcg aaaccctata tgcagaaggc atccattcag cgcaagcttt
     6961 aaaaaatagt catcttctcg ttgcttaatg gctataaatt tgttagaata ttagcaatca
     7021 gaagtgcatt gagttggtct gttacagaga gcggtggtgt tgagaaatcc gcacagatgt
     7081 caaggctggt agctgaggat aagaaatcag atatgaaaag tagcagatcc attttatggt
     7141 ctgaaacagt ggtggtaccg cggaaatcgt aacacgaaat tcgtccctgt ccagtgtaag
     7201 ctggataggg attatttggt ttcatttgaa agaagatgat ggcttattgt taaaatattg
     7261 ttagaagtat ataatagaaa aactttgccc aaagtggaaa cagaacggct gctattacgt
     7321 caacgaaaag gggacaaggc attgttccag aagcggcttc agctctgatt gaaattggtt
     7381 ttaccttact tgatttgcat aaaattgagc tgggttgcta cgactacaac aagcaaagtc
     7441 aggcagtggc tcgcaaatta ggctttacct tagaagccaa tgcccgtgac cgtaaggacg
     7501 ttcaaggtcg ccgctgtggc gacatgcgtt ttgggttact gagaagtgag tgggaggagc
     7561 agaaacaaaa atgaacctta tcatcattgg tgctcaagcg tcgggcaaga tgaccattgg
     7621 gcaagaagtt accaggcaga caggcatgac tttgtttcat aatcacgatt ctattgattt
     7681 tgttttacgg tttatgcctt ggtctcaaga gagcactgcc ttgattgaac gtatccgttt
     7741 tgcttttttt gaaacctttg ctaagacagg tcaagacatg atttttacta ttgtaattga
     7801 cttcaatgat ccaaatgatg tagcaatgct tgaaaagatt caggctgttt ttcagtctta
     7861 tgaccaagag gttctctttg tcgaattaaa aacagatata gaggaacgtc ttaaacgcaa
     7921 tcgcacagaa aatcgtctca aacataaacc tcttaaacgc aacatcgagt ggtcagaaca
     7981 agatattcaa tccacgatgg catatgctgt ttttaatcca gaagaaccac ccaaaacgct
     8041 cacgcattac caaaaaatca ataataccca tctcaccgct gctgaaacag cgcagcttat
     8101 tatccaaaaa atgactcata tcaaggagaa ctaagatgac agaactatca cctaaataca
     8161 atcctgccga ggttgaggca ggtcgctatc aaaaatggct tgatgcagat gttttcaagc
     8221 catcaggaga ccaaaaagca aaaccgtatt ctatcgtgat tccaccgcca aatgtgactg
     8281 gtaagttgca cttgggacat gcttgggaca caacacttca agatattatc attcgtcaaa
     8341 aacgcatgca gggctttgat acgctttggc ttccagggat ggaccatgca ggaattgcga
     8401 cacaggctaa ggtagaggag cgtctgcgcg agcaggggat ttctcgttac gaccttggtc
     8461 gtgacaaatt cctagacaag gtctgggaat ggaaagacga atatgccact acgattaaag
     8521 agcagtgggg caagatggga ctttctgtgg attacagccg tgaacgtttc acactagatg
     8581 agggcttgtc aaaagcagtt cgcaaggttt tcgttgacct ctacaaaaaa ggctggattt
     8641 accgtggtga attcatcatc aactgggatc ctgctgccag aactgccctt tctgacatcg
     8701 aggttgtcca caaggatgtt gagggagctt tctaccacat gaactatatg ttggaagatg
     8761 gctcacgcgc ccttcaagtg gcaacaacgc gaccagaaac catgtttgga gacgttgccg
     8821 ttgccgtaaa cccagaagat cctcgttaca aagatttgat tggcaaacat gttcttttac
     8881 caatcgtgaa taaattgatt ccaatcgtgg gtgacgagca tgccgaccct gaatttggga
     8941 ctggagttgt gaaaatcacg cctgcccatg atcctaacga tttcgaggtt ggtcaacgcc
     9001 ataatctacc acaagtgaat gtcatgaacg atgacggtac catgaatgag ttagctggcg
     9061 actttgcagg catggaccgt tttgaagctc gtcaagctac cgttgctaaa cttgaagaac
     9121 ttggcgccct agtaaacatc gaaaaacgtg ttcactcagt aggtcactca gaacgttctg
     9181 gtgcagtcgt tgagcctcgt ctatccactc aatggtttgt aaaaatggat gagcttgcta
     9241 aacaagctat ggacaatcaa gaaacagatg accgagtaga tttctaccca cctcgtttca
     9301 acgatacctt cctccaatgg atggaaaatg tccatgactg ggtaatctct cgccaattat
     9361 ggtggggaca ccaaatccca gcttggtaca atgcagaagg tgagatttac gttggcgaag
     9421 aagcaccaga aggtgatggc tggactcaag atgaagatgt tcttgacact tggttctcat
     9481 ctgctttatg gccgttctca accatgggat ggcctgatac agattcagaa gatttcaaac
     9541 gttatttccc aacgtcaacc ttagtaacag gttat
//
LOCUS       DAXMQE010000052         9494 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.052, whole genome shotgun sequence.
ACCESSION   DAXMQE010000052 DAXMQE010000000
VERSION     DAXMQE010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9494)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9494)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9494
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.052"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            <1..201
                     /locus_tag="ACF4ZO_001717"
     CDS             <1..201
                     /locus_tag="ACF4ZO_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015055948.1"
                     /note="Converts oxaloacetate to phosphoenolpyruvate using
                     ATP as an energy source; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxaloacetate decarboxylase subunit alpha"
                     /protein_id="HFD5487228.1"
                     /translation="SAPVTTNRPADQLSPEFEVLKAEVADLAQTDEDVLTYALFPSVA
                     KPFLTTKYQTDDVIKVTAFIKA"
     gene            244..558
                     /locus_tag="ACF4ZO_001718"
     CDS             244..558
                     /locus_tag="ACF4ZO_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5487229.1"
                     /translation="MTYSFIDILQVTLVSLFLVLTCLTGIMGLMMLSGKLLSQEKKTL
                     SQQASSIPQEQEADKLSGEALETLLAKDELARIAVMTSLAYASQEESGKRFEVIAVER
                     KS"
     gene            558..908
                     /locus_tag="ACF4ZO_001719"
     CDS             558..908
                     /locus_tag="ACF4ZO_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin/lipoyl-containing protein"
                     /protein_id="HFD5487230.1"
                     /translation="MKRYEVTVNGQVYEVSLRELADGETVEVSQPAAPATEKEMNANA
                     AGGGIQVKAPMSGTVLSIFATEGKAVKKGEAVLVLEAMKMENEILAPADGLVSKIHVV
                     ANQTVESEQVLISF"
     gene            918..2048
                     /locus_tag="ACF4ZO_001720"
     CDS             918..2048
                     /locus_tag="ACF4ZO_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium ion-translocating decarboxylase subunit
                     beta"
                     /protein_id="HFD5487231.1"
                     /translation="MLDVLNQMVQSSGLAHLTVNNLIMICLACFFLYLGIKKEYEPYL
                     MVPIAFGILLVNLPMAGLMDHPANGNPGGLLYYLYKGTSLGIYPPLIFLCLGASTDFG
                     PLIANPKTILLGGAAQVGIFLAFFLAIMLGMTPQEAASVGIIGGADGPTAIYVTTKLA
                     PDLLSTIALAAYSYMALVPIIQPPIIKLLTTKAERQVKMTQARTVSQKEKIIFPIMVT
                     IFVSLLVPSATTLVGCLMLGNLVREIKIVPKIVENLQQVVMFCITIILGLTVGAKANG
                     DLFLSATTLKIIALGLIAFAAGTAGGVLMGKVMYYLSGNKVNPMIGAAGVSAVPMAAR
                     VVQKVGQEEDPSNFLLMHAMGPNVAGVIGSAIASGALLAFFG"
     gene            complement(2249..3133)
                     /gene="citG"
                     /locus_tag="ACF4ZO_001721"
     CDS             complement(2249..3133)
                     /gene="citG"
                     /locus_tag="ACF4ZO_001721"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046917 - triphosphoribosyl-dephospho-CoA
                     synthase activity [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA];
                     GO_process: GO:0019361 -
                     2'-(5''-triphosphoribosyl)-3'-dephospho-CoA biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase CitG"
                     /protein_id="HFD5487232.1"
                     /translation="MTKAVLTSISQLALKALLYEVSLSPKPGLVDRFDNGAHDDMSFM
                     TFIDSMIALSPFFQAYIETGFAYAKEEPLLLFNRLRQLGQKAEEIMFCATQGINTHKG
                     LNFSMALLLGATGAYLARTPHLMTDLGCFSKEDTLAICRLVKPMTAHLIQADLGHLNT
                     KKEFTYGEQLFVTYGIKGPRGEASEGFTTLTDHALPYFRQMISQNDPETSQLRLLVYL
                     MSIVEDGNLIHRGGIEAWKGVKADMRLLLQQDLSTTDLRLALSSYNQCLINQHLSPGG
                     AADLLALTFYFAFLEKLL"
     gene            complement(3126..3821)
                     /locus_tag="ACF4ZO_001722"
     CDS             complement(3126..3821)
                     /locus_tag="ACF4ZO_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFD5487233.1"
                     /translation="MNPIIEAVKQNLDLSRNIPLKIAFYNALKKTIILRQIPVGSRIN
                     EKEFSIALNISRTPIRYALGLLSEEHLVEHIPKKGIIVKGVSIKDACEIFEIRKALET
                     LATVQAMHLMTEEDFKVMHNLLEDCETFIAEDDTNRILDNFNAFNNLIYSYSQMVRLK
                     EIVTELQAYLVYFRKISISSVERRKRALSEHWMIYRGMKNKDHEQITLITHEHLNSSL
                     EFILKEMRPEQND"
     gene            complement(3979..5382)
                     /locus_tag="ACF4ZO_001723"
     CDS             complement(3979..5382)
                     /locus_tag="ACF4ZO_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003088270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CitMHS family transporter"
                     /protein_id="HFD5487234.1"
                     /translation="MLLTMLAYAMIIVFMYVVMKKKMTPFTALVMIPLIMTIAVILTG
                     SADFNADAKFVAFVGDGGIAKDLTAIGPMVMYGINNTAKTGIMLLFAILFFSVMLDAG
                     LFDPITEKMIRFAKGDPMKVLIATAVVAAAVSLNGDGTTTTLICCSAFLPIYKKLDMK
                     IMNLGVLIILQNTIMNLLPWGGPTARAMSVLGVGPEILGYLAPGMILSLLYVICWVAP
                     SMGRKERARLGVIDLSEEDMRQLTDITDPDTLFIRRPKNFVFNAILTIGLITWLVAGS
                     FNKSIAMAPLLLFAVGTCIALMVNYPVLKDQSKRIGDNAGDAVQVVILVFAAGIFMGL
                     FQGSGMASALAQSFATIIPKQLAGFWGLVIALVSAPGTFFISNDGFYYGILPVLAEAG
                     AEYGFSNMAMALASLMGQAFHLLSPLVAFIYLLLRLTGLDMGEWQKEAAKYALIIFVI
                     FVVTIIAMGQMPLYIPQ"
     gene            5762..6085
                     /locus_tag="ACF4ZO_001724"
     CDS             5762..6085
                     /locus_tag="ACF4ZO_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5487235.1"
                     /translation="MQFLQKWFKHSKKEKLKESSPLSTEIEPSENWEKIPAYIPADKS
                     DYKKVTLITSAIAAGDRPNSQFKVKRILKRNPEAITVSLIASSIAAGVYPESQFRVTS
                     IYCKR"
     gene            6142..6537
                     /locus_tag="ACF4ZO_001725"
     CDS             6142..6537
                     /locus_tag="ACF4ZO_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein subunit"
                     /protein_id="HFD5487236.1"
                     /translation="MLRKFKITIDGKEYLVEMEEIGAPAQAAAPAQPISTPVPVSTEA
                     SPQVEEAQAPQPVAAAGADAIPSPMPGTILKVLVAVGDQVTENQPLLILEAMKMENEI
                     VASSAGTITAIHVGPGQVVNPGDGLITIG"
     gene            6582..7703
                     /locus_tag="ACF4ZO_001726"
     CDS             6582..7703
                     /locus_tag="ACF4ZO_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019323213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium ion-translocating decarboxylase subunit
                     beta"
                     /protein_id="HFD5487237.1"
                     /translation="MDTLIAGITSITISQIVMMVIGALLMYLGIKKEYEPTLLVPMGL
                     GTILVNFPGSGVLTQVVNGVEQEGVFDALFNFGIGTELYPLLIFIGIGAMIDFGPLLQ
                     NPFMLLFGAAAQFGIFFVVVVAVLAGFDIKEAASIGIIGAADGPTSIFVANQLAKDLL
                     GPITVAAYSYMALVPIIQPFAIKLVTTKKERRIRMTYKAENVSQMTKILFPIIITLVA
                     GFVAPISLPLVGFLMFGNLLRECGVLDRLSQTAQNELVNIISILLGLTISIKMQADLF
                     LNVQTLLIIVFGLLAFIMDSIGGVMFAKFLNLFRKEKINPMIGAAGISAFPMSSRVIQ
                     KMATDEDPQNFILMYAVGANVSGQIASVIAGGLLLAYFS"
     gene            7721..7855
                     /locus_tag="ACF4ZO_001727"
     CDS             7721..7855
                     /locus_tag="ACF4ZO_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OadG-related small transporter subunit"
                     /protein_id="HFD5487238.1"
                     /translation="MTINMDHLISSFELMALGMAGVFIVLGILYLVAEILIKLFPVSK
                     "
     gene            7891..8199
                     /gene="citD"
                     /locus_tag="ACF4ZO_001728"
     CDS             7891..8199
                     /gene="citD"
                     /locus_tag="ACF4ZO_001728"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_component: GO:0009346 - ATP-independent citrate lyase
                     complex [Evidence IEA];
                     GO_function: GO:0008815 - citrate (pro-3S)-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006113 - fermentation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase acyl carrier protein"
                     /protein_id="HFD5487239.1"
                     /translation="MDIKQTAVAGSLESSDLMITVSPNDEQTITITLDSSVEKQFGNH
                     IRQLIHQTLVNLKVTAAKVEAVDKGALDCTIQARTIAAVHRAAGIDQYDWKEIDSWNV
                     "
     gene            8187..9074
                     /gene="citE"
                     /locus_tag="ACF4ZO_001729"
     CDS             8187..9074
                     /gene="citE"
                     /locus_tag="ACF4ZO_001729"
                     /EC_number="4.1.3.34"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_component: GO:0009346 - ATP-independent citrate lyase
                     complex [Evidence IEA];
                     GO_function: GO:0008815 - citrate (pro-3S)-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006084 - acetyl-CoA metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006113 - fermentation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="citrate (pro-3S)-lyase subunit beta"
                     /protein_id="HFD5487240.1"
                     /translation="MERLRRTMMFVPGANAAMLRDAPLFGADSVMFDLEDSVSLKEKD
                     TSRALVHFALKTFDYSSVETVVRVNGLDSCGALDIEAVVLAGVNVIRLPKTETAQDIV
                     DVEAVIERVERENGIEVGRTRMMAAIESAEGVLNAREIAKASKRLIGIALGAEDYVTN
                     MKTRRYPDGQELFFARSMILHAARAAGIAAIDTVYSDVNNTEGFQNEVRMIKQLGFDG
                     KSVINPRQIPLVNEIYTPTKKEIDHAKQVIWGIREAESKGSGVISLNGKMVDKPIVER
                     AERVIALATAAGVLSEEDI"
     gene            9077..>9494
                     /locus_tag="ACF4ZO_001730"
     CDS             9077..>9494
                     /locus_tag="ACF4ZO_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_component: GO:0009346 - ATP-independent citrate lyase
                     complex [Evidence IEA];
                     GO_function: GO:0008814 - citrate CoA-transferase activity
                     [Evidence IEA];
                     GO_process: GO:0006084 - acetyl-CoA metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase subunit alpha"
                     /protein_id="HFD5487241.1"
                     /translation="MVTNKLGRDIPQPYADQYGVFEGELANIKQYDESSRRIKPVKPG
                     DSKLLGSIREAIEKTGLTDGMTISFHHHFREGDFIMNMVLEEIAKMGIKNLSIAPSSI
                     ASVHEPLIDHIKNGVVTNITSSGLRDKVGAAISEGLM"
BASE COUNT         2946 a         1878 c         1936 g         2734 t
ORIGIN      
        1 tcagctcctg tcaccacaaa tcgtcctgca gatcaactaa gtcctgaatt cgaggtgtta
       61 aaagcagaag tagcagattt agcccaaacg gacgaagatg tgctgactta tgccctcttc
      121 ccaagcgtag caaaaccgtt tttaacaacc aaataccaaa ctgatgacgt cattaaagtg
      181 actgccttta tcaaagcata ataggctatc ttaatcagat agaaacaaaa atatggagat
      241 caaatgacct attcctttat tgatatctta caagttacct tagtatcctt gttcttagtg
      301 ttaacctgtt taacagggat tatgggatta atgatgctaa gtggtaaatt attgtcacaa
      361 gaaaaaaaaa ctctctctca acaagcttcc agcattcctc aagagcaaga agctgacaag
      421 ttgagtggag aagctctcga aactctttta gccaaagacg aattggctag aattgctgtt
      481 atgactagtc ttgcttatgc tagccaagaa gagtcaggaa aacggtttga agttattgcc
      541 gtggaaagga aatcctaatg aaaagatatg aagtgactgt caatggacag gtttatgaag
      601 tgagtttacg tgaactagct gatggagaaa ctgttgaagt tagccagcca gcagcacccg
      661 ctactgagaa agaaatgaat gccaacgctg ctggcggtgg cattcaggta aaggctccaa
      721 tgtctggaac agtcttgtct atctttgcta cagaaggaaa agctgttaaa aaaggagaag
      781 ctgttctggt cttagaggcc atgaaaatgg agaatgaaat tctagcacct gcagatggtc
      841 tggtttcaaa aattcatgtt gtggctaacc aaacggtcga gtctgaacaa gttttgattt
      901 cattctagga ggaaaccatg ctagacgtac tcaatcaaat ggtccaatcg tcaggattgg
      961 ctcatctaac tgttaataat cttatcatga tttgcttggc ctgtttcttt ttataccttg
     1021 gtatcaaaaa ggaatatgag ccttacctta tggtaccaat cgcctttggg attttactcg
     1081 ttaatttgcc tatggcggga ttgatggacc accctgccaa tggtaatcct ggtggccttc
     1141 tttattacct atataaggga actagcctag ggatttaccc acctttaatt tttctttgtt
     1201 tgggggcatc aactgacttt ggtcccttga ttgccaatcc taaaaccatt ttactaggag
     1261 gcgcagcaca agttgggatt ttcttagcct ttttccttgc tattatgtta ggcatgacac
     1321 ctcaagaagc ggcttctgtc gggattattg gtggtgccga tggaccaaca gctatttatg
     1381 tgacgacaaa gttggcgcct gatttactct ctactatcgc cctagcagct tattcttaca
     1441 tggctctggt acctattatt caacctccta tcattaaact cttgactacc aaggcggaac
     1501 gccaagtgaa aatgactcaa gcaagaactg tttcacaaaa agaaaaaatc attttcccga
     1561 ttatggtaac aatctttgtc agccttttgg ttccaagtgc tacaaccttg gttggctgtt
     1621 tgatgctggg aaatctggtc agagaaatta aaattgttcc taaaattgta gagaatctcc
     1681 aacaagtggt tatgttttgc attactatca ttttagggtt aaccgttggt gctaaggcca
     1741 atggagatct ctttttatca gccacaacct tgaaaattat tgcccttggg ctaatcgcct
     1801 ttgctgctgg tacagcaggg ggtgtcttga tggggaaggt catgtactat ttatctggta
     1861 acaaagtgaa ccctatgata ggagcagcag gtgtttcagc tgttccgatg gcagcgcgag
     1921 tggtccaaaa ggtcggacaa gaagaagatc caagtaattt cttactcatg cacgccatgg
     1981 ggcccaatgt agctggcgtt attggctcag ccattgcttc aggtgccttg ctggccttct
     2041 ttggctaatt gtgaaaaagg attagtaaat taatcttaat aaatcattat caggagttgg
     2101 aagcaatcta gctccttttt tagtagaaag ctcgagtgat aaactattcc aaaataatta
     2161 taaaaaaaga ctgtcctgat tgtacggact atatcaattg acttttatag tctagctgaa
     2221 atagcagtgc aaaactaaga cactcgtttt aaagtagttt ttctaaaaaa gcaaaataaa
     2281 aggtcagagc caataaatct gccgcgcccc cagggcttaa atgctgatta atgaggcatt
     2341 gattgtagga ggacaaagcc aatcttaggt cagttgttga taaatcttgt tgcaggagta
     2401 gtcgcatatc tgccttaacg cctttccatg cttcaatccc tccacgatga atcagatttc
     2461 catcttcaac aatagacatc aaataaacaa gaagacgaag ctgactggtt tcggggtcat
     2521 tttgacttat catctgacga aagtagggca aggcatggtc tgttaaggtc gtgaatccct
     2581 cgcttgcctc accccgaggt cctttgatgc cataagttac aaagagttgc tccccataag
     2641 tgaactcttt tttagtgttc aaatgaccaa ggtctgcttg aatcaaatgt gccgtcatag
     2701 gttttactaa acgacagata gctagagtat cttccttgct aaaacaccct aaatcagtca
     2761 ttaagtgagg tgttcttgct agataggccc cagttgcacc aagaagtaaa gccatggaaa
     2821 aattcaagcc tttatgagtg ttaattccct gagtagcaca aaacatgatt tcctcggcct
     2881 tttgacctag ttgtctaaga cggttaaaca gaagaagtgg ctcttctttt gcataagcaa
     2941 aacctgtttc gatataagcc tgaaaaaaag gagagagtgc tatcatactg tcgataaagg
     3001 tcataaagga catgtcatca tgggcaccgt tatcaaatcg atcaactaaa ccaggttttg
     3061 gagatagtga gacttcataa agcaaagctt ttaaggccag ttgactaata cttgttagaa
     3121 ctgccttagt cattttgctc aggcctcatt tcttttaaga taaattcaag tgagctattc
     3181 aagtgttcat gtgtaatcaa cgtaatttgc tcatgatctt tgttcttcat acctcggtaa
     3241 atcatccagt gttcagatag agctcgttta cggcgttcaa ctgaagaaat cgaaattttt
     3301 ctaaagtaga ccaaataagc ttgcaattct gtcacaattt cttttaagcg gaccatttgg
     3361 ctatagctgt aaatcaaatt gttaaaggca ttaaaattat ccaaaatacg attggtgtca
     3421 tcctctgcga taaaggtttc acagtcttcc aacaagttat gcatgacttt aaaatcttct
     3481 tctgtcatta aatgcatcgc ttgcactgtt gcgagagtct ctagagcttt tcgaatttca
     3541 aaaatttcac aggcatcctt gatactaact cctttgacaa taatgccttt tttaggaatg
     3601 tgctctacaa ggtgttcttc agacaataat cccaaagcgt agcgaatagg tgtcctgcta
     3661 atattaagcg caatggaaaa ctctttttca ttaatgcgac ttccaacagg aatttgtcgc
     3721 aaaataatgg tctttttaag agcgttataa aaggctattt tcaaagggat atttcttgat
     3781 aggtcaagat tttgtttaac ggcttcgata ataggattca tgtcatctcc ttaatgctag
     3841 tgtcctcact ttattatact taaatttgtg aaacattcca ataggactag atgagttctg
     3901 aaaaattaaa gccatgctca caaaaggaca tgactttaat catctcataa ggaataaggt
     3961 agtagtgtta tcgttggttt attgtggaat gtaaagtggc atttgtccca tggcaataat
     4021 ggttaccaca aagataacaa agatgataag ggcatattta gcagcctctt tttgccattc
     4081 ccccatgtca agacctgtca agcgaagaag aagataaatg aaggcaacta atggactaag
     4141 taagtggaag gcttgtccca tgagggaagc aagtgccata gccatgttac tgaaaccata
     4201 ttcagcacca gcttctgcaa gaacaggcaa gataccatag taaaaaccat cattggagat
     4261 aaagaaggta ccaggtgcag aaactaaggc aataacgaga ccccagaaac ctgccagttg
     4321 ttttggaata atggttgcaa aactttgtgc aagagcgcta gccataccag aaccttgaaa
     4381 aagacccata aagataccag cagcaaagac gagaataacc acttgaaccg catcaccagc
     4441 attgtcacca atgcgttttg attgatcttt aagcactggg taattgacca tcaaggcgat
     4501 acaagttccc accgcaaaaa gaagaagcgg tgccatagca atagatttgt tgaaagagcc
     4561 agcaactaac caagtgatta atccaatggt taagatagca ttgaaaacaa agtttttagg
     4621 acgacgaata aaaagggtat ctgggtcagt aatgtctgtg agttgacgca tgtcttcttc
     4681 agacaagtca ataacaccaa gtcttgcacg ttctttacgc cccatgcttg gagcaaccca
     4741 acaaatcaca taaagaagag ataaaatcat acccggtgca agatagccaa gaatttcagg
     4801 accgacacca agaacagaca tcgcacgagc agtagggcca ccccatggca gtaagttcat
     4861 aatagtattt tgaagaataa tcaagacacc taggttcatg attttcatgt ccaatttttt
     4921 atagataggt aagaaagcag agcaacaaat taaagtagtg gttgttccat caccattaag
     4981 agatactgca gcagcaacga cagctgttgc gataagcacc ttcattggat cacctttagc
     5041 aaagcgaatc atcttttcag taatcggatc aaacaatcct gcatctaaca tgacagagaa
     5101 gaacaaaatg gcaaatagca acatgatacc tgttttagca gtattgttga taccatacat
     5161 aaccattggt ccgatagctg ttaggtcttt agcaattcca ccgtcaccaa caaaggcaac
     5221 aaatttggca tctgcattga agtcagctga accagtcagt ataacagcaa tcgtcatgat
     5281 taatggaatc atgaccaaag cagtaaaagg ggtcattttt ttcttcatta ccacgtacat
     5341 aaagacaata atcatggcat aagccagcat tgttaataac atcattgtta tctccttttt
     5401 caagttatga tttcagtata gatgaaagcg cttataaaat aaatacttct ttgtgcagaa
     5461 agacacaaaa aaaacaattt gaaaattaat tttgaaaacc atttttatta catcagatga
     5521 ctttaaattt tctataataa tgatgaacct agttagatca agcttttctt gctatcagta
     5581 tcttgatctc agtttttcaa cagttaccta aaaataaaat aaaaggtaac tgttgaaaaa
     5641 ctttatgaaa tattgaaagc gctcttagaa agaacacaaa aaagccatct caaaaaagat
     5701 tggtagtata taataaactt actagttccc taaataggta aatgtgaaaa agaggtagct
     5761 catgcagttt ttacaaaaat ggtttaaaca ctctaaaaaa gagaagttga aagaatcctc
     5821 gccccttagt acagaaatag aaccttctga aaactgggaa aagattcccg cttatattcc
     5881 tgcagacaaa agtgattaca aaaaggttac tttaattacc agtgctattg ctgctggcga
     5941 tagacctaat agtcaattca aggttaaacg cattctcaag cgcaatcctg aggcaatcac
     6001 tgtttcttta attgcttcaa gtatcgctgc aggtgtttac ccagaaagtc agtttcgggt
     6061 gacatccatc tattgcaaaa ggtagtcggt gaacgatact ttagacgaac tcatgacaca
     6121 ataacatata ggagaaaaat gatgttacga aaatttaaaa ttaccattga cggtaaagaa
     6181 tatcttgtag aaatggaaga aatcggtgct cctgcccaag cagctgcccc cgctcaacca
     6241 atatccactc cagtacctgt ctctactgaa gcaagcccac aagtggagga agcgcaagca
     6301 ccacagccag tagctgcagc gggagcggat gccattccat caccaatgcc tggaaccatc
     6361 ttaaaagtct tagtagcagt gggagaccaa gtaaccgaaa atcagccact attgatttta
     6421 gaagccatga agatggaaaa tgagattgtg gcctcatcag caggaaccat tacagctatc
     6481 cacgtcggtc caggtcaagt ggtcaatcct ggtgatggtc tcattacaat tggttaacag
     6541 tactataact agaataaata gacagaaaag gaagtgaatt tgtggacact ttaatcgcag
     6601 gaataacctc catcaccatt tctcaaattg ttatgatggt cattggtgcc ctcttaatgt
     6661 atctaggaat taaaaaagaa tacgaaccaa ctctacttgt gccaatgggg cttggaacaa
     6721 tccttgtgaa tttccctggc tcaggagttt taacacaagt cgttaacgga gtcgagcaag
     6781 aaggggtttt tgatgccctc ttcaattttg ggattggaac agaactttac ccactgttga
     6841 ttttcattgg tattggcgcc atgattgact ttggtccctt gcttcaaaac ccattcatgc
     6901 tcttgtttgg tgctgcagct caattcggaa ttttctttgt tgtcgttgtt gccgtactgg
     6961 ctggctttga cattaaagaa gcagcttcaa tcggcattat cggagcagca gacggaccga
     7021 cttctatctt tgttgccaac caactggcca aggatttact gggtccaatt acggttgcag
     7081 cctattctta catggctctg gttcctatta tccaaccatt tgccattaaa ttagtgacaa
     7141 cgaaaaaaga gcgccgtatc cgtatgactt acaaagctga gaatgtatct caaatgacta
     7201 aaatcttatt cccaatcatc attaccttag tagcagggtt cgtcgcccca atttctctac
     7261 ctttagttgg ctttttgatg ttcggtaact tattacgtga gtgtggtgtg ctcgatcgcc
     7321 tgtcacaaac tgctcaaaat gaattggtaa acattattag tatcttgctt ggattgacca
     7381 tctctattaa aatgcaggca gacctgttct taaatgtaca gacactctta atcatcgtct
     7441 ttggtttact tgcttttatc atggattcta tcggtggggt catgtttgcc aaatttctca
     7501 atctcttccg aaaagagaag attaatccaa tgattggcgc tgcgggtatt tcagcttttc
     7561 caatgtcaag tcgtgtcatt caaaaaatgg caacagatga agacccgcaa aactttatcc
     7621 tcatgtatgc tgtaggtgcc aatgtctctg gccaaatcgc ctctgttatc gcaggtggtt
     7681 tgttgctagc ttactttagc taagaaagga aggaaacctt atgacaatta atatggacca
     7741 tttgattagt tcctttgagc taatggcgct tggtatggca ggtgtcttta ttgtgttagg
     7801 cattctctat cttgtcgcag agatcctgat caaacttttc ccagttagta aataacaata
     7861 tcatttaaga aaatcaagga ggtaaacgca atggatatta aacaaactgc cgttgctggt
     7921 tcacttgaat caagtgacct aatgattaca gtatccccta atgacgagca aaccattaca
     7981 ataaccctag acagtagtgt tgaaaaacaa tttggcaatc acattcgtca actcattcat
     8041 caaaccctag tgaatttgaa ggtgacggct gccaaagtag aggctgttga taaaggtgct
     8101 ttagattgca ccattcaagc gagaaccatc gcagctgttc atcgcgctgc tggtattgac
     8161 caatacgatt ggaaggagat tgactcatgg aacgtttaag aagaacaatg atgtttgtgc
     8221 caggtgccaa tgccgccatg cttcgagatg ctcctttatt tggggctgat tccgtcatgt
     8281 ttgacttgga agattctgtt tcactcaaag aaaaagacac ttctagagct ctcgttcatt
     8341 ttgcgctaaa aacttttgat tattcaagcg ttgaaacggt tgttcgtgtg aatggtcttg
     8401 attcttgtgg agctttagac atcgaagctg ttgttttggc aggtgtcaac gtgattcgtc
     8461 ttccaaaaac agagactgca caagatatcg ttgatgtgga ggctgttatt gaacgtgtcg
     8521 aacgcgaaaa cggcattgaa gttggccgca cacgcatgat ggcagccatt gaatcagccg
     8581 aaggtgttct aaatgctcgt gagattgcca aagcttctaa gcgcttgatt ggtattgctc
     8641 ttggggcaga agactatgtc acgaatatga aaacgcgtcg ttacccagat ggtcaagaat
     8701 tattctttgc tcgtagcatg attttacacg ctgctcgtgc tgctggaatt gctgccattg
     8761 atactgttta ttctgatgtc aataataccg aagggttcca aaacgaagtt cgcatgatca
     8821 aacagttagg atttgacggt aaatcagtaa tcaaccctcg tcaaattcct ctggtcaatg
     8881 agatttatac cccaacaaaa aaagaaattg accatgctaa acaagtcatc tggggaattc
     8941 gtgaagctga aagcaaaggc tctggcgtta tttccttaaa tggaaaaatg gttgataaac
     9001 caatcgttga acgtgcagaa cgtgtcattg ccctagcaac agcagcaggt gttttatctg
     9061 aggaggacat ttaaagatgg taacaaataa actcggtcgc gacattcctc aaccatacgc
     9121 cgaccagtat ggtgtctttg aaggagaact cgcaaatatc aaacagtatg acgaatcaag
     9181 tcgccgtatt aaaccagtta aacctggaga ttctaaatta ttaggctcta tccgtgaagc
     9241 gattgaaaaa actggcttaa cagatggtat gaccatttca ttccaccacc atttccgtga
     9301 aggggatttc attatgaata tggtcttgga ggaaattgcc aaaatgggca ttaaaaacct
     9361 atctattgct ccaagttcca tcgctagtgt acatgagcct ttgattgatc acatcaaaaa
     9421 tggtgtggtt accaacatca cttcatctgg tcttcgtgac aaagtagggg cagccatttc
     9481 agaaggacta atgg
//
LOCUS       DAXMQE010000053         9075 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.053, whole genome shotgun sequence.
ACCESSION   DAXMQE010000053 DAXMQE010000000
VERSION     DAXMQE010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9075)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9075)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9075
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.053"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            complement(6..293)
                     /locus_tag="ACF4ZO_001731"
     CDS             complement(6..293)
                     /locus_tag="ACF4ZO_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5487242.1"
                     /translation="MLNFKKNVSDYSKYYILSIVLLWIGMFFVPWDKTLFGVSIYLFV
                     MQKLFIVFGLTAIFMAFVSKKINLFIWGILFIFAFWINMFLLFSVLPILGN"
     gene            complement(287..862)
                     /locus_tag="ACF4ZO_001732"
     CDS             complement(287..862)
                     /locus_tag="ACF4ZO_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipase"
                     /protein_id="HFD5487243.1"
                     /translation="MKKVINTILLAACFLFFLGNFTTNVLAEGINDKMENGTESDISF
                     QNGELLKNYLILEGERVYFDYDRATQDKVSDDVLEMGMLVEAISKDYSEKTFTPDKYF
                     KASWPVHGNYCGPGHNGNNFTLPVVDVLDQGCQNHDSCYKWGAGIGANCECNRQLVNY
                     IKVYRRWMPANVLGVADAIRVYFETVGSIGC"
     gene            complement(1338..2117)
                     /gene="spek"
                     /locus_tag="ACF4ZO_001733"
     CDS             complement(1338..2117)
                     /gene="spek"
                     /locus_tag="ACF4ZO_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptococcal pyrogenic exotoxin SpeK"
                     /protein_id="HFD5487244.1"
                     /translation="MKKNTLTLLFLVCVSLALYTTESVFSDTYNTNDVRNPRNIYAPR
                     YDKDEILDNRRLKEIYNKEIIEKNNISINAKQGTQLIFNTDENTTVWNDNTFKKVISS
                     NLSPSQERMFNVGDHVNIFAIVKSYHVVCKEQFNYSDGGIIKTSDVKPEEKAIYINIF
                     GEKELRTLTAKDKITFKNNIVTLQEIDVRLRKSLMGDSKIKLYEYDSLYKKGFWDIHY
                     KDGGIRHTNLFTYPDYTDNETIDMSKVSHFDVHLNEDFSKD"
     gene            complement(2984..3625)
                     /locus_tag="ACF4ZO_001734"
                     /pseudo
     CDS             complement(2984..3625)
                     /locus_tag="ACF4ZO_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527920.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
     gene            complement(3738..4430)
                     /locus_tag="ACF4ZO_001735"
     CDS             complement(3738..4430)
                     /locus_tag="ACF4ZO_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AP2 domain-containing protein"
                     /protein_id="HFD5487245.1"
                     /translation="MKTTEIKEIGNVFNNLRVISYAGKNKHNKKLAFCECLLCGAKKN
                     MILTEVRTGKSKSCGCLATIKAKERQMVHGYSGTKVHRAWKGMRQRCTNPNYEHYHRY
                     GGRGITFSDEWNDFQIFLNDMGFPPSDRHQLDRIDNDGNYCKENCRWVLPKENCNNRK
                     TYHNKTGFTGVTENTSKKGRYSAVFHVNRKHIQVGTFDSPLEAYRARVNAIKKYNKEH
                     NTNLKYIEVEDL"
     gene            complement(4666..5220)
                     /locus_tag="ACF4ZO_001736"
                     /pseudo
     CDS             complement(4666..5220)
                     /locus_tag="ACF4ZO_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922095.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
     gene            complement(5332..5787)
                     /locus_tag="ACF4ZO_001737"
     CDS             complement(5332..5787)
                     /locus_tag="ACF4ZO_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HFD5487246.1"
                     /translation="MIINLTSLIHLFGDLVRTVEIHVFTLFVCFDIITGLTKGITNKR
                     ANSTKGLSGIIKHFLVVLLVYTVYPYLILLGAKPLAVAFVLFFIACYGISIVENWGQL
                     GLPMPSFVRSFFEKLKRDTDQFDIATIKIDKTGVKVEAPQVDLKQKEEE"
     gene            complement(5803..6408)
                     /locus_tag="ACF4ZO_001738"
     CDS             complement(5803..6408)
                     /locus_tag="ACF4ZO_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1366 domain-containing protein"
                     /protein_id="HFD5487247.1"
                     /translation="MRNWKVTGKYPQLDSTGAVASTHIIITAEDGSVISQPIKQDLTS
                     TNDTEIIKATLEEFKKSEYVEIAMGEAVQKVDDLEKISQETANTAKTAQTAAGLAKVS
                     AERTQRMINLQTIHVLTSGGKVEPDIYKGMLELIEPAKQGEYQAYDVFTVVDESHEDQ
                     AGEGNLVFVHVNEPFTYDKQTLKELESEDKVTVIKYADLVK"
     gene            complement(6411..6839)
                     /locus_tag="ACF4ZO_001739"
     CDS             complement(6411..6839)
                     /locus_tag="ACF4ZO_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1617 family protein"
                     /protein_id="HFD5487248.1"
                     /translation="MDLTLKNKDLNTLYSVLDKIKVTNMRANRGRAKLLAKVETKLSE
                     YAKDEIDIIDQYVAKNDDDKWITDDKGNPKIEDTSKLAELNDFLDELASEPVVIKGGE
                     YSKRFIDFLEYLAESEDEFTSEEIIIIDNILEQFEESKGE"
     gene            complement(6848..8629)
                     /locus_tag="ACF4ZO_001740"
     CDS             complement(6848..8629)
                     /locus_tag="ACF4ZO_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gp58-like family protein"
                     /protein_id="HFD5487249.1"
                     /translation="MSRDPTYTINEHDLSFADGRFYVTFKADKSSETVRLNSSCLGNT
                     IIKKLQVEDDNTMHDFVKPKVTTQQAFGLAQQVKELDLQLKDPKSDLWGKIKFNNKAM
                     LVEYANKEMSSAIAQSAEQILLQVKSIDDERYSKFEQTLNGIKQTVKSESVESARTQL
                     ASMFDSRISGLDGKYSRLSQTIDSLSSRLDDGVGNYSTLSQKVSGIDLRVSNAANDVS
                     RLSQTAQGLQSQITNANQNYSSLSQTVQGLQTTVRDNQSNATSRINQLSDLISTKVSK
                     GDVETTIAQSYDKIAFAIRDKLPASKMSGSEIISAINLDRSGVKITGKNITLDGNSYI
                     SNAVIKDAHIANMDAGKINTGYLNANRIATEAITGEKIKMDYAFFNKLTANEGYFRTL
                     FAKDIFATSVQSVTLSASKITGGVLAATNGASQWDLNNANMTFNRDATINFNSKNNAL
                     VRKDGTHTAFVHFSNATPKGYRGSALYASIGITSSGDGIDSASSGRFCGVRFFRYAEG
                     LQHTAKVDQAEIYGDDIVFSDDFNIDRGFKMRPSLMPKMVDLNKMYQAILALGRCWLH
                     ANNTAWSWNFDTRSAIIAEYNAHINNL"
     gene            complement(8644..>9075)
                     /gene="hylP"
                     /locus_tag="ACF4ZO_001741"
     CDS             complement(8644..>9075)
                     /gene="hylP"
                     /locus_tag="ACF4ZO_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_192934711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronidase HylP"
                     /protein_id="HFD5487250.1"
                     /translation="PNFSSALNITSANEGGSAMQIRGVEKALGTLKITHENPNVKANY
                     DENAAALSIDIVKKTNGEGTAAQGIYINSTSGTTGKLLRIRNLSDDKFYVKSDGGFYA
                     KETSQIDGNLKLKDPTANDHAATKAYVDKAISELKKLILKK"
BASE COUNT         2638 a         1902 c         1469 g         3066 t
ORIGIN      
        1 ttaaactaat ttcccaaaat tggtaatacg gaaaataaca aaaacatatt aatccaaaat
       61 gcgaaaataa ataatattcc ccaaataaat agatttattt ttttagacac aaaggccatg
      121 aagatagccg tcaaaccaaa cactataaat aacttttgca taacaaacag ataaatcgaa
      181 acaccgaata gagtcttatc ccaaggaaca aagaacattc ctatccataa taacactata
      241 ctcaaaatat agtacttcga ataatcacta acgttttttt tgaaatttaa catcctatag
      301 aacctactgt ctcaaaatat actctaatag catcggctac gccaaggaca ttcgctggca
      361 tccatcgtct ataaactttt atgtaattaa ctagctgacg gttacattca caattagcac
      421 caataccggc accccactta tagcaactat cgtggttttg gcaaccttga tccaaaacat
      481 ctactactgg caacgtaaag ttattcccat tatgacctgg tccacaatag ttaccgtgga
      541 caggccaact agctttaaaa tacttatctg gggtgaatgt cttctcagaa taatccttac
      601 ttatagcttc aactaacatt cccatctcta gaacatcatc tgatacttta tcttgagttg
      661 ctctatcata atcaaagtat actcgttcac cttctaggat aagataattt tttaggagtt
      721 caccattttg gaagctaata tcactttcag tgccattttc cattttatca tttatccctt
      781 cagctaatac atttgtagta aaattaccta aaaagaataa aaaacaagca gctaatagaa
      841 tagtatttat tacttttttc ataaattttc tccaactatt ttaataacag agaaactatt
      901 aagtgctacc ccaatatgtc aacaaacctc ctttcttaaa actaaggtag accttatctc
      961 aagaagaata ttacacttaa aatattacaa atacaagtct tttttttatt taattttttt
     1021 ggtaaaatta aatatagtgg taattttaaa ttaacgtatt tgaaatattt ggtagctact
     1081 atttcctgaa aaagaaataa acaaacgggc gtatgacggg ttctacattc ctccttcata
     1141 ggttaataaa aattgaagat gaaagaaatt aaaaaaataa ttccttaaaa aacacaaaaa
     1201 ccgcccagaa ttatctgagc ggttttgtca tattcctcgg ttgaccgata gtgatgccta
     1261 gaagtctact aaaaccgtct aattcatcaa aatctattta aatagactaa aaattaaatt
     1321 aaaatagcat tcaaccacta atctttagaa aaatcttcgt ttaagtgaac atcaaagtga
     1381 ctaactttac tcatatcaat cgtttcatta tctgtatagt cggggtaagt aaataaattg
     1441 gtgtgtctaa tgccaccgtc tttataatga atatcccaaa accctttttt atacaaagaa
     1501 tcgtactcat acaattttat tttgctgtcc cccatcaaac ttttcctaag tctaacatca
     1561 atctcctgaa gagttacaat attattttta aaggtaatct tatctttagc tgttaatgtt
     1621 cgtaattctt tttcaccaaa aatattaata taaattgctt tttcttctgg ttttacatca
     1681 cttgttttta ttattccccc atcactataa ttgaattgtt ccttgcatac aacatgatat
     1741 gactttacta tagcaaaaat attcacatga tcaccaacat taaacattct ttcctgtgaa
     1801 ggagaaagat tactagatat gactttctta aaagtgttat cattccaaac tgtagtattt
     1861 tcatccgtat taaaaatcaa ttgcgttcct tgtttggcat ttatcgatat attatttttt
     1921 tcaataattt ctttattata tatttctttt aatcttctat tatccaaaat ttcgtcttta
     1981 tcatatctag gagcatatat gttccttgga tttctaacat catttgtatt gtacgtatct
     2041 gaaaagacac tctcagtagt gtatagagca agcgatacac acacaaggaa taacaaagtc
     2101 aaggtatttt ttttcatttt ttctcctaac attttttaag tttaatcaat ttgtttagca
     2161 agtatactat atttaaataa taattcaact ataattttaa aaaaacacaa aaaaaacatt
     2221 atacagctat aaagcttaat ataataggat tttatgtata caattattta acagcatcta
     2281 ttcaagatag cctacttcat caggttggta tgactaagtt tttaacttat cttcccccct
     2341 ttttttgttt tagaagataa aagaattttc ttgattttgc acacaaaaaa ccgcccagaa
     2401 attatctgag cggttggttt ttattcaaaa tacaacaaat tgtatataat tttgtttgag
     2461 gacacaagat atagtgattt tttcgcccaa aaactttatt tgtgaaataa aataatatat
     2521 aattgtatca acaaataagc tctagtagct tagatgggct agagctaact agtcaaatag
     2581 caaatcttta aaaaggaggt tggagtatgg aaattttcct cctcacatta gttagtaatt
     2641 ttgtggttac cctcactgca aattgcttag ctgatgtcgt gcgtgactat ttacacaaaa
     2701 aatagtacgt acattacatt ttttgtttaa gagtgggtcg gcaaacctgc tcttttttat
     2761 gtccaaaaat aaaagcacag ccggcaaact gtgctttttc tgaggttgga gtttcctctt
     2821 acattttttg ttcgtcacct acggtgctag gtgtacagca atacaaacaa caagagcata
     2881 aacaacagag gcacagttat ttgttatctt tatattacct gttttgattt gctaagtcaa
     2941 gaaaaacagt attattttat tattaataat aaaataataa ctcctaattt aatttacccc
     3001 aaatactgat gcggttgcca tccttatcag tctgcccaat agctaggtag tcacgcatac
     3061 ctgaacctcc aacatagcta atccagtagt aaccattcgc gtagccctcg ctatcaaagc
     3121 tgacagtatc gtcttgctta tagctaccta ctacttcgct ggctaagctt ggccaacgcc
     3181 taatattaat ctctgcgaca tcaagcgtaa aggtgcctgt ttttgctgtc tctacgatag
     3241 tgtccgagtt ttgtggtgct gtatctactg tctggtgagt gtgatcaact ggcaatctaa
     3301 tccagccaat aacgccagta aagtcgcgga tattaaagcg agcgggtccg cctacctgca
     3361 gactatccca gttaccgtca atattttgct caacagtttt aatcgtatag ccatcactat
     3421 cctcgatgac agctcctgta tgtccgtagg gactaccagc tacctccatg acaaaaaggt
     3481 cactagcttt gggattgact ccaggggcat tatatatgac ctctagccct tgcgcagatg
     3541 cgctatttaa caggtctatg gcattacccc ataaatcaat gccgaaccag tttttgacga
     3601 taaaacatgg taagtcagca cactgcatta tcctttaatt ataagcctct ccgtaatttc
     3661 atttctgaaa atacttgtat agcttataac actctttcga gctcttgctt tcacaagaga
     3721 tgagactata tcttcaatca taaatcttct acttctatat attttaaatt ggtgttatgc
     3781 tctttattat atttttttat agcgttaact ctagctctgt aagcttctag cggactgtca
     3841 aaagtcccaa cttggatgtg tttacgatta acatgaaaca ctgcagaata acgccctttt
     3901 ttagaagtgt tttctgtgac tccggtaaaa cctgtcttat tgtggtaggt tttacgattg
     3961 ttgcaattct ctttaggtag aacccaacgg cagttttctt tacaataatt tccgtcgtta
     4021 tcaatcctat caagctgatg tctgtcactt ggcggaaaac ccatatcgtt caaaaatatt
     4081 tgaaaatcat tccactcatc gctaaacgta atccctcgac caccatatct atggtagtgt
     4141 tcgtaatttg gattcgtaca cctttgacgc atccctttcc aggctctatg cacctttgtt
     4201 ccgctatacc catgtaccat ctggcgctct ttggctttta tcgtagctag acatccgcat
     4261 gatttgcttt ttccagtcct aacttctgtc aaaatcatat ttttcttagc tccacatagt
     4321 aaacactcac aaaaagctag ctttttattg tgtttgtttt ttcctgcgta gctaattact
     4381 ctcaagttat taaaaacatt tccaatttct tttatttcag tagtcttcat aggttaaacc
     4441 tcaaacttca tctaacctat tatatcataa ttgccccgtg ctgtcttgcg attgcaagca
     4501 cttagtcgtt gaagcttcct ctactgttac catagaggct cgcctgctga tttcccaatc
     4561 attgtaattt tttaaccgtc acgctctctg ttgccagaca cgttgtggtt tacaatgctc
     4621 taagggagtc ccagcaattc tcggggttag gaacccaatt tactaagttc cataagcacc
     4681 atctttatca actcccatgc ctgaattggc aaggtcgaca cagtatttta caatctcatt
     4741 tgcggttgtc attgtttcct ccttattact ttttaagact tcggcatccc aaaactgcaa
     4801 gccattctcc ttgataattt ggataagtag ctccgcatag ccactcgctg tggcataacc
     4861 tgcctccttg atagcatgac aggccttttt gtaatcagtc tcaccaacga ctgccttata
     4921 gcgtggattg tcgtttaaaa atttgccgtg atcaagaatt gactcatccc aactaccgta
     4981 agccctaaag cggtctacaa tatccgtcac aactcctggt tgatactcct cttgcgtctt
     5041 agtatcaaat gacttaccag tccaagagct atcagcctta atcccaaata aagcgttatg
     5101 tggggcatgt ttgccccaac cgctctcaag gattgcttgc gctgcggtca aggatggtag
     5161 aattttatat ttaacccatc catctaagca tccttgctta atgttatcta aaaatgccat
     5221 ctaccatcct ctcctataaa gggagccaaa atcaaagcaa tcacggccag tggaaaatat
     5281 agcactatga tcgctatgat gacggctatt tgtgtgattg cttttttcat cttactcctc
     5341 ttctttttgt tttaaatcaa cttgtggcgc ctcgacttta acacctgtct tatcaatttt
     5401 aatcgtggca atgtcaaatt gatcagtgtc acgtttgagt ttttcgaaaa atgatctgac
     5461 aaaacttggc atcggcaagc ccaactgacc ccaattttcg acaattgata tgccataaca
     5521 tgcgataaaa aagaggacaa aggcaactgc caaaggctta gcgccaagca aaatgaggta
     5581 aggatagaca gtataaacta acaatacaac taaaaaatgc ttgataatgc cagatagtcc
     5641 ctttgtgcta ttagccctct tgtttgtaat accttttgtt agccctgtga taatgtcaaa
     5701 acaaacaaaa agtgtaaaaa cgtggatttc aacggtacga actaaatcac cgaaaaggtg
     5761 aataagactt gttaaattaa taatcatcta accacctcaa tcctacttaa ctaagtccgc
     5821 atacttaatg actgtgactt tatcctctga ctctagctct ttaagcgtct gtttgtcata
     5881 agtaaacggc tcgttgacat gtacaaagac taggttccct tctcccgctt gatcttcgtg
     5941 cgactcatct acaacagtaa acacgtcata agcctgatac tcgccttgtt tagcaggctc
     6001 aataagctct aacatacctt tgtagatatc gggttcaact ttcccaccac ttgtcaatac
     6061 gtggatggtt tgcaagttaa tcattcgctg tgtacgctct gcggacacct tagctaatcc
     6121 tgcagctgtt tgagcagtct tggcagtatt agcagtttcc tgtgagattt tttctaagtc
     6181 atccactttt tgcacggctt cgcccatagc gatttcgacg tattcagatt ttttaaattc
     6241 ttccaaagta gctttgataa tctctgtgtc attagttgag gttaagtcct gcttgattgg
     6301 ttgagagatg actgagccat cctcagcagt gataataata tgtgtgcttg cgactgctcc
     6361 tgtgctgtca agttgtggat attttcctgt cactttccaa tttctcatgt ttattctcct
     6421 ttactttctt caaattgctc taaaatgttg tcgattatga taatttcttc tgatgtaaac
     6481 tcatcttctg actctgccag atattctaaa aaatcgataa agcgcttaga gtactcgcca
     6541 ccttttataa cgacaggctc gcttgctaac tcgtctaaaa agtcgttaag ctcagctaac
     6601 tttgaggtgt cctcaatttt tggattacct ttgtcatctg taatccactt gtcatcatca
     6661 tttttagcga catattgatc aataatatcg atctcatctt tggcatactc gcttagctta
     6721 gtctctactt ttgcaagcag cttagcgcgc ccacgatttg ctcgcatgtt cgtgactttg
     6781 attttgtcta gtacactata tagtgtgttt aaatctttgt ttttaagcgt taaatccatt
     6841 gtttctccta taagttatta atgtgtgcgt tatattctgc gatgattgcg ctgcgtgtat
     6901 caaaattcca cgaccaagcc gtgttattag catgcagcca gcagcggccg agagccaaaa
     6961 ttgcctggta catcttgttt aagtcgacca tttttggcat taggctaggc cgcatcttaa
     7021 agccacgatc gatgttaaaa tcgtcgctaa agacaatatc atcaccataa atttcggctt
     7081 gatcgacctt tgctgtatgc tgtaaccctt cagcgtaccg gaaaaaccta actccacaga
     7141 aacgtccaga cgaagcgctg tcgatgccat ctcctgatga ggttatcccg attgacgcat
     7201 acaacgctga gcctctatag ccttttggcg tcgcattact aaaatgtaca aaggcagtat
     7261 gtgtgccatc tttacgtact aaggcattgt ttttgctatt aaaattaatt gtggcatctc
     7321 gattaaaggt catattggca ttatttaggt cccactgact tgccccattt gtagcggcta
     7381 atacacctcc agtaattttg ctagctgata gtgttacaga ttggactgat gttgcaaaga
     7441 tgtctttggc aaacaacgtc ctaaaatatc cctcgttagc agtgagttta ttaaaaaagg
     7501 catagtccat cttaattttc tcaccagtaa tggcctcggt tgcaatccta ttagcattaa
     7561 gataaccagt attaatctta ccggcatcca tgttagcaat atgagcatct ttgatgacag
     7621 cgttgctgat gtagctgtta ccatcaagag tgatattttt tccagtgatt ttaaccccag
     7681 acctatcaag attgattgcc gagataatct cactgccaga cattttgctt gctgggagtt
     7741 tatccctgat tgcgaaggct atcttgtcgt aactctgagc aatagttgtc tcaacatcac
     7801 cttttgatac ctttgtgctg atcaggtcac ttaactgatt aatccgactt gtagcatttg
     7861 attgattatc acgtacagtt gtttgtagtc cctgtacagt ctgagacaaa ctgctgtaat
     7921 tttggtttgc atttgtgatt tgtgactgca atccttgtgc tgtctgagac aatcgagaaa
     7981 catcattagc tgcattacta actcgtaaat caatgccact taccttttga gatagcgttg
     8041 agtagttacc aacaccatca tcaagacgac tgctaagact atcaattgtt tggcttaaac
     8101 gactgtattt gccatcaagt ccactaatac gactatcaaa cattgatgct agctgagtac
     8161 gtgcggattc aactgactca cttttgacag tttgtttgat accattcaga gtttgctcaa
     8221 atttggaata tcgttcatca tcaatagatt tgacttgtaa caatatctgc tcagctgatt
     8281 gcgcaatggc acttgacatc tctttgttgg cgtactcgac tagcattgcc ttattattga
     8341 acttgatttt gccccacaaa tctgacttag ggtcttttag ctgtaaatca agctctttga
     8401 cctgctgagc tagtccaaaa gcttgttgag tggtaacttt aggctttaca aagtcgtgca
     8461 ttgtattgtc atcctcgacc tgtagctttt tgattatggt attgccaagg caactactgt
     8521 taagtctcac agtctcactt gacttatctg ccttaaaggt cacataaaaa cgaccatctg
     8581 caaaagataa gtcgtgctcg tttattgtat atgttgggtc tctgctcatt tattctcctt
     8641 aatctatttt tttagtatga gtttttttaa ctcagaaatt gctttatcta cataagcttt
     8701 ggttgccgca tgatcattcg ctgtggggtc cttgagtttc aggttgccat caatctgcga
     8761 agtttccttg gcataaaaac caccgtcaga cttgacgtag aacttatcat cactaaggtt
     8821 tctaatccta agcaacttcc ctgtcgtgcc tgaggttgag ttaatgtaga ttccctgagc
     8881 ggctgttcct tcaccgtttg tctttttgac aatatcaatg gataacgctg cagcgttttc
     8941 atcgtaattt gccttaacgt ttgggttttc gtgagtaatt tttagcgttc ctagcgcttt
     9001 ttcgacgcct ctaatttgca tcgcactacc gccttcgttg gcactggtta tattaagtgc
     9061 cgaggaaaaa ttagg
//
LOCUS       DAXMQE010000054         9009 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.054, whole genome shotgun sequence.
ACCESSION   DAXMQE010000054 DAXMQE010000000
VERSION     DAXMQE010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9009)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9009)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9009
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.054"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            152..901
                     /gene="truA"
                     /locus_tag="ACF4ZO_001742"
     CDS             152..901
                     /gene="truA"
                     /locus_tag="ACF4ZO_001742"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HFD5487251.1"
                     /translation="MVRYKATISYDGTLFSGFQRQRHLRTVQEEIEKTLYKLNNGTKI
                     IIHGAGRTDAGVHAYGQVIHFDLPQEQEVEKLRFALDTQTPEDIDVVNIEKVADDFHC
                     RYQKHLKTYEFLVDNGRPKNPMMRHYTTHYPYTLNIKLMQEAINGLVGTHDFTGFTAA
                     GTSVQNKVRTITKATVSRDEKTDFLVFTFSGNGFLYKQVRNMVGTLLKIGNGQMPVEQ
                     VKVILSSKNRQLAGPTISGNGLYLKEICYEN"
     gene            891..1655
                     /locus_tag="ACF4ZO_001743"
     CDS             891..1655
                     /locus_tag="ACF4ZO_001743"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008972 - phosphomethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HFD5487252.1"
                     /translation="MKTDYIVTISGNDILSGGGLYADLATYIRYDLQAFVAVTCLTTR
                     SEEGFSLFPVAKEIFRDQLNSFTNAPISAIKIGLLPNAEMCEIVLDFIKGHVGIPVVL
                     DPVLACKEIDDVKIVPLRQEILQLLPYVTVVTPNLVEAQLLSQKEIVSLKDMQEAAKY
                     FYQLGAKQVVIKGGNRFSQKKAIDLFYDGKEIVTLECPVLEKNNIGAGCTFASSIASQ
                     LVKKKTPLEAVKNSKELVYQAILQSDRYGVKQSYAK"
     gene            1645..2115
                     /locus_tag="ACF4ZO_001744"
     CDS             1645..2115
                     /locus_tag="ACF4ZO_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HFD5487253.1"
                     /translation="MQNSKIRQMSLTGILTALVVVLGRFVMLPTPTGFLTLLDAGIYA
                     VSFSFGSAQGAIVGGLSGFLIDLVAGYPQWMFHSLIAHSVQGYFAGWRGRKRWFGVVI
                     GSFIMIFWYFLGSLMLGYGLSGSLAGIWGNVMQNTLGLFVGFIIFKAILRKKER"
     gene            2129..2689
                     /locus_tag="ACF4ZO_001745"
     CDS             2129..2689
                     /locus_tag="ACF4ZO_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HFD5487254.1"
                     /translation="MLNNLEKQTREIVIDVVERSAIQPGNLFVLGLSSSEILGSRIGK
                     QSSLEVGQIVVEVVLDELNKRGVHLAVQGCEHVNRALVVERHVAESKQLEIVNVVPNL
                     HAGGSAQMAAFQLMSDPVEVEEVIAHAGLDIGDTAIGMHIKRVQIPLIPCQRELGGAH
                     VTALASRPKLIGGARADYNMDIIRKS"
     gene            complement(2754..3599)
                     /locus_tag="ACF4ZO_001746"
     CDS             complement(2754..3599)
                     /locus_tag="ACF4ZO_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HFD5487255.1"
                     /translation="MTFILHYLEQSHIENIGLTIFKKLVSLIILLLFFAILKRVTNYL
                     FEKTINKSFAYSRQSEARKKTLSKLTHNILNYLLYFLLIYWILSLFGIPVSSLLAGAG
                     IAGVAIGLGAQGFLSDVVNGFFILFENQFEVGDNVTISDIEGSVFGVGIRTTQIRGFD
                     GTLHFIPNRSITVVSNKSRGNMRALIEIPLYSTVNLSQVTRIIDEVNQKELPNHPQIV
                     GKPNILGPQNNSNGQFTFRIAIFTENGEQFKIYHTFYRLYQEALLKEGIQLPTAISYS
                     ITSKS"
     gene            3920..5203
                     /gene="tig"
                     /locus_tag="ACF4ZO_001747"
     CDS             3920..5203
                     /gene="tig"
                     /locus_tag="ACF4ZO_001747"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005854 - nascent polypeptide-associated
                     complex [Evidence IEA];
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0051083 - 'de novo' cotranslational protein
                     folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HFD5487256.1"
                     /translation="MSTSFENKATNRGVITFTISQDKIKPALDKAFNKIKKDLNAPGF
                     RKGHMPRPVFNQKFGEEVLYEDALNIVLPEAYEAAVTELGLDVVAQPKIDVVSMEKGK
                     EWTLSAEVVTKPEVKLGDYKNLVVEVDASKEVSDEDVDAKIERERQNLAELIIKDGEA
                     AQGDTVVIDFVGSVDGVEFDGGKGDNFSLELGSGQFIPGFEDQLVGAKAGDEVEVNVT
                     FPESYQAEDLAGKAAKFMTTIHEVKTKEVPELDDELAKDIDEDVDTLEDLKVKYRKEL
                     EAAQETAYDDAVEGAAIELAVANAEIVDLPEEMIHEEVNRSVNEFMGNMQRQGISPEM
                     YFQLTGTTQEDLHNQYSAEADKRVKTNLVIEAIAKAEGFEATDSEIEQEINDLATEYN
                     MPADQVRSLLSADMLKHDIAMKKAVEVITSTASVK"
     gene            5420..5995
                     /gene="rpoE"
                     /locus_tag="ACF4ZO_001748"
     CDS             5420..5995
                     /gene="rpoE"
                     /locus_tag="ACF4ZO_001748"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HFD5487257.1"
                     /translation="MKLDVFAGQEKSELSMIEVARAILEERGRDNEMYFSDLVNEIQN
                     YLGKSDAGIRHALPFFYTDLNTDGSFIPLGENKWGLRSWYAIDEIDEEIITLEEDEDG
                     AQKRKKKRVNAFVDGDEDAIDYRDDDPEDEDFTEESAEVEYDEEDPDDEKSEVESYDS
                     ELNEIIPEDDFEEVDINEEDEEDEEDEEPVL"
     gene            6252..7856
                     /locus_tag="ACF4ZO_001749"
     CDS             6252..7856
                     /locus_tag="ACF4ZO_001749"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003883 - CTP synthase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006241 - CTP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HFD5487258.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NIDPGTMSPYQHGEVYVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITDALKEKIKRAASTTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGSENVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPVE
                     QGIKNKLAQFCDVNSEAVIESRDVEHLYQIPLNLQAQSMDQIVCDHLKLNAPQADMTE
                     WSAMVDKVMNLRKTTKIALVGKYVELPDAYLSVVEALKHSGYANDTAIDLKWVNANDV
                     TVDNAADLLGDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGICLGMQLTCVEFA
                     RHVLNMEGANSFELEPSTKYPIIDIMRDQIDIEDMGGTLRLGLYPCKLKPGSKAAMAY
                     NNQEVVQRRHRHRYEFNNKFRPEFEAAGFVFSGVSPDNRLVEIVELKEKKFFVAAQYH
                     PELQSRPNRPEELYTAFVTAAIKNSN"
     gene            8024..8950
                     /locus_tag="ACF4ZO_001750"
     CDS             8024..8950
                     /locus_tag="ACF4ZO_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFD5487259.1"
                     /translation="MKTIRIAKYLGILFLLITLISVGASFYFFHVAQIREEKSFINNK
                     KRSTNNPLYPAEQSFDALPYEKRQLTNRGLKQVGWYLPAAQKTKKTAIVVHGFTNDKE
                     DMKPYAMLFHDLGYNVLMPDNEAHGESEGNLIGYGWNDRLNVMAWTDQLIKENPESQI
                     TLFGLSMGAATVMMASGERLPAQVTSLIEDCGYTSVWDELKFQAKAMYNLPAFPLLYE
                     VSALSKIRAGFSYGEASSVKQLAKNKRPTLFIHGDKDDFVPTKMVYDNYKATKGPKEI
                     LIVKGAKHAKSFETNPEQYQKKIAAFLKKVEK"
BASE COUNT         2949 a         1369 c         1944 g         2747 t
ORIGIN      
        1 gaaaaaagga gagagtttgg aggaaatagc tttcttatag cttttaaatc gctagtagct
       61 tagagtaagc ttcaatacgt ctttcatttg tttgggtaca gtttgattaa aaatagtttc
      121 tcttacgttt aagaaatgtt aaaatagtaa catggtaaga tacaaagcaa cgatttccta
      181 tgatgggact cttttttcgg gttttcaaag acaaagacat ttacgtacgg ttcaagaaga
      241 gattgaaaaa acactctata aattaaataa cggtacaaaa attataattc atggtgcagg
      301 acgtacggat gcaggagtac atgcttatgg acaggtgatc cattttgatt tgcctcaaga
      361 acaagaagtt gaaaaattgc gatttgctct tgatacacag actcctgaag atattgatgt
      421 tgttaatata gaaaaagtgg ctgatgattt tcactgtcgt tatcagaagc atttaaaaac
      481 ttatgaattt ttagttgata atggtcgacc taaaaatccg atgatgcgac actataccac
      541 tcattacccg tatactctta atattaaact tatgcaagaa gctattaacg gtctggtagg
      601 tacacacgat tttactggtt ttacagcagc aggaacttcg gtacaaaata aggtgcgaac
      661 gattaccaaa gcaacggtat ctcgggatga aaaaactgat tttttggtgt ttactttttc
      721 aggaaatggt tttctctata agcaggtgag gaatatggtg ggaactttgc tgaaaattgg
      781 taatggtcaa atgccagttg aacaagttaa agtgattttg agctccaaaa atcgtcagct
      841 agctggacca acgatatctg gaaatgggct ttacttgaag gagatttgtt atgaaaactg
      901 attatatcgt gactatatct gggaacgata ttttaagtgg aggtggcctc tatgctgatt
      961 tagcgactta cataaggtat gacctacagg cctttgtagc ggtaacttgt ttaactacta
     1021 gatctgaaga gggctttagt ctatttccgg tagctaaaga aattttccgt gatcagttga
     1081 acagttttac gaacgctcca atttctgcta ttaaaattgg tttgttacct aatgcggaaa
     1141 tgtgtgaaat agttttggat tttataaagg ggcatgtggg aatcccagtg gttttagatc
     1201 ctgttctagc atgtaaagaa atagatgatg ttaaaatagt tcctctaaga caggagattt
     1261 tacaattatt gccttatgta actgttgtta ctccaaattt ggtagaggct cagctattat
     1321 ctcaaaaaga gattgtttct ttaaaagata tgcaagaagc tgctaaatat ttttatcaac
     1381 ttggggcaaa acaggtggtt atcaagggtg gtaatcgatt tagtcagaaa aaggctattg
     1441 atctttttta tgacggtaaa gagattgtta ccttggaatg tcctgtactt gagaaaaata
     1501 atattggcgc aggctgtact tttgcatcta gtatcgctag tcagttagta aagaaaaaaa
     1561 cgccactaga agctgtgaaa aactcaaaag agttagtcta ccaagctatt ttacaatctg
     1621 atagatacgg agtaaaacaa agttatgcaa aatagtaaga tacgacaaat gagtttaaca
     1681 gggatattga cagcattggt tgttgtttta ggaagatttg tcatgctacc tactccaaca
     1741 ggttttttaa cgctgttgga tgcaggaatt tatgctgtca gcttttcctt tggatcagct
     1801 caaggagcta ttgtgggagg gttatcaggt tttttaatcg atttagtggc aggataccct
     1861 cagtggatgt ttcatagttt gattgctcac agtgtccaag ggtattttgc gggatggaga
     1921 ggacgcaagc gttggtttgg tgttgtgata ggttctttta tcatgatttt ttggtatttt
     1981 ttaggctctc ttatgcttgg ttatggcctt tcgggatctt tagccggtat ttggggaaac
     2041 gtcatgcaaa atacattagg actttttgtt ggttttatta tctttaaggc catattaagg
     2101 aaaaaagaga gataaggaga gtgagaagtt gttgaataat ttagagaaac aaacaaggga
     2161 aatcgttatt gatgttgtag aacgctctgc tattcaacca ggtaatcttt ttgttctagg
     2221 tctttcatct agcgaaattt tgggtagtag aattggaaaa caatctagtc tagaagtagg
     2281 tcaaatagtt gttgaagttg tgttagatga gttaaataag cgtggtgttc atttggctgt
     2341 acaaggttgt gaacacgtaa atcgtgcctt ggtagtagag aggcatgtgg cagaatctaa
     2401 gcagttagag attgtcaatg tggttccgaa tcttcatgct ggtggcagtg ctcagatggc
     2461 tgcttttcaa cttatgtcag accctgtcga agtagaagaa gttattgcac acgctggact
     2521 tgatataggt gatactgcta taggaatgca tattaagcgt gttcagatcc ctctgattcc
     2581 ttgtcaacga gagctaggag gtgctcatgt gacagctttg gctagtcgac caaaattaat
     2641 tggtggagct agggctgatt acaatatgga tattatccgt aaatcctaaa cccttttttc
     2701 tggaataaaa caattggtgt tttttctaga aaaaaggatt ttttaagatt atattaagat
     2761 tttgaggtga tagaatagct gattgcagtc ggtaattgaa tgccttcttt gagtaaagct
     2821 tcttgataaa gtctataaaa agtatggtaa atcttaaatt gttctccatt ttctgtgaaa
     2881 atagcaattc taaaagtgaa ctgtccatta gagttatttt gaggccctaa aatatttggt
     2941 ttgccaacga tttgaggatg gtttggcaat tccttttgat tcacttcatc aatgattcga
     3001 gtgacttggc tcaaattaac agtggaataa agaggaattt caattaaggc acgcatatta
     3061 ccacgagatt tgttgctgac aacggtgatg ctacggtttg ggatgaaatg tagtgttcca
     3121 tcgaatccac gaatttgagt agttctaatt ccaacaccaa agacactgcc ttctatgtca
     3181 gagatagtaa cgttatctcc tacttcaaat tgattctcaa ataagataaa aaagccattg
     3241 acaacgtcag ataaaaatcc ttgtgcacct aacccgattg ctactccagc aattccagct
     3301 cctgctagaa gactagagac aggtatgcca aataagctaa gtatccaata aatgagaaga
     3361 aaatataata agtagtttaa aatgttgtga gtgagcttag agagtgtttt tttgcgagct
     3421 tcactttgtc ttgaataagc aaacgatttg ttaatggttt tttcaaaaag atagttagta
     3481 acacgtttta aaatagcaaa aaagagtaat agaataatga gagacactag ctttttaaaa
     3541 atcgttaagc caatattttc gatatgagac tgctctaggt aatgtaatat aaatgtcatg
     3601 agaaatcctt tctttgatag tttatcaaaa aaaaaccaat cttgaaaaga gataaattaa
     3661 tattttaacc aaagttatga taattgtttt atcataaaga atgccatagt catccgttgt
     3721 gataatgctt gaaaatagtc agttagtaag cgaaaaagtc taacattaac ctttataaat
     3781 tgaaaataac tgttagtaga ctaatgacag gtagatactc ttaatagcgc gtttgatttc
     3841 acgcataaaa agctttaaaa acgctttaaa ttatgataaa atgaactgta tcgaaattat
     3901 tttaaggaga aatgacttaa tgtctacatc atttgaaaac aaagctacaa atcgtggcgt
     3961 gattacattt acaatcagtc aagataaaat aaaaccagct cttgataaag cttttaataa
     4021 aatcaaaaaa gacttaaatg caccaggttt ccgtaaagga cacatgcctc gtccagtctt
     4081 caaccaaaaa tttggtgaag aagttcttta tgaagatgct ttgaatattg tattgccaga
     4141 agcttatgaa gcagctgtga cggaacttgg tcttgatgtg gttgcacaac caaaaatcga
     4201 cgttgtgtca atggaaaaag ggaaagagtg gacactttct gctgaagttg tgacaaaacc
     4261 tgaagtgaaa cttggtgatt acaaaaacct tgttgtagaa gttgatgctt caaaagaagt
     4321 ttcagatgaa gacgtggatg ctaaaattga gcgcgaacgt caaaaccttg cggaactcat
     4381 tattaaagac ggtgaagcag ctcaaggtga cactgttgtg attgactttg ttggttcagt
     4441 tgatggtgtt gagtttgatg gcggtaaagg agataacttc tctcttgaac ttggttcagg
     4501 acaatttatc ccaggttttg aagatcaact agttggtgct aaagctggcg atgaagtaga
     4561 agttaatgtc acattcccag aatcttacca agcagaagat cttgcaggta aagccgctaa
     4621 atttatgaca actattcacg aagtcaaaac aaaagaagta cccgagcttg atgatgagct
     4681 tgcaaaagat attgatgaag atgttgacac acttgaagac ttaaaagtaa aatatcgtaa
     4741 agaacttgaa gcagctcaag aaactgctta tgatgatgct gttgaaggag ctgcgattga
     4801 attagcagtt gcaaatgctg aaattgttga tttacccgaa gaaatgattc atgaagaagt
     4861 caaccgttca gtgaatgaat ttatgggcaa catgcaacgt caaggaatct cacctgaaat
     4921 gtacttccaa ttgactggta caactcaaga agatttacat aaccaatatt cagctgaagc
     4981 tgacaaacgt gttaaaacaa accttgttat tgaagcaatt gctaaagcag aaggttttga
     5041 agcaacagat agtgaaattg aacaagaaat taatgacctt gcaacagaat ataacatgcc
     5101 agctgaccaa gttcgttctc ttctttcagc agatatgttg aaacatgata ttgcaatgaa
     5161 aaaagcagtt gaagtgatta caagcacagc aagcgttaag taatcttatt aaggaacaaa
     5221 acgtacaagc cggattagaa cgtctttcta gtctggtttt tctttttcta aagaaataat
     5281 aaggaattag ttaaacgtta ttttaatgaa ttagctttag agatttgtca agaagaagtg
     5341 atatgagttg ataaaagttt tgacgaatta ctttttttag cgtaaaatgg tagagaatga
     5401 taaaataagg agaactgcct tgaaattaga cgtatttgca ggacaagaaa aaagcgagct
     5461 ttccatgatt gaagtggcgc gtgccatttt ggaagaacgc ggtcgcgaca atgagatgta
     5521 ctttagcgat ttagtcaatg agattcaaaa ttacttagga aaatctgatg caggtattcg
     5581 tcatgcatta ccatttttct atactgactt aaatacggat ggctcattta ttcctctagg
     5641 tgaaaacaaa tggggacttc gttcgtggta tgctattgat gaaattgatg aagaaattat
     5701 tactctagaa gaagatgaag atggcgcaca aaaacgtaag aaaaaacgcg ttaatgcttt
     5761 cgtggatgga gatgaagacg ctattgatta tagagatgat gatccagaag atgaagattt
     5821 cacagaagaa tcagctgagg ttgaatatga tgaagaagat ccagatgatg aaaaatcaga
     5881 agtggagtca tatgattcag aattgaatga aattattcct gaagatgatt ttgaagaagt
     5941 tgatatcaat gaagaagacg aagaagatga agaagatgaa gaaccagttc tctaatgtct
     6001 ttagttcaga aataaaaatg taattatcat ttgacaaatt gtctattata gtttatatta
     6061 ttattcgggc acctctttat gaggtcaggc aaaagctctc tagttaatag ggggctattt
     6121 ttgttttcta gaataatgcc agtttgcctc tatatttaga aaactaaggt gatacctaac
     6181 caatgtggaa ccaactaata gggaattaac aagaaagcaa tgcttttatt cagcttatat
     6241 aaaggagtac tatgacgaaa tacatttttg taactggtgg tgttgtatca tcaattggca
     6301 aaggaattgt tgcggcaagt cttggccgat tgttaaaaaa tcgtggactt aaggtgacga
     6361 ttcaaaaatt tgatccttat attaatattg atccagggac gatgagcccc tatcagcatg
     6421 gagaagtata tgtgacagat gacggtgctg aaaccgactt ggatttgggt cactatgaac
     6481 gttttattga tatcaatctt aataaatatt ccaatgttac aacaggtaaa atttatagtg
     6541 aagtccttcg taaagaacgt aaaggcgagt accttggagc gactgttcag gtgattcctc
     6601 atatcacaga tgcccttaaa gaaaaaatca aacgcgcagc ttcaacaacg gactctgatg
     6661 taattattac tgaggtcggg gggactgttg gcgatattga aagtttaccg ttcttagaag
     6721 ctcttcgtca gatgaaagct gatgttggtt ctgaaaatgt gatgtatatt cacaccacct
     6781 tgttgccata tttaaaggca gcgggtgaaa tgaaaactaa gccaacgcaa cattccgtta
     6841 aagaattgcg tggtttaggg attcaaccga atatgttggt tattcgtacg gaagagccag
     6901 ttgagcaggg gattaaaaat aaattggctc agttctgtga tgtgaattca gaagctgtta
     6961 tcgagtcacg tgatgtagaa cacttgtatc aaattccatt gaacttgcaa gctcaatcaa
     7021 tggatcagat tgtttgtgat catttgaaat tgaatgcgcc acaagctgat atgaccgagt
     7081 ggtcagctat ggttgacaag gtgatgaatt taagaaaaac aacaaaaatt gccttggttg
     7141 gtaaatatgt ggaattgcca gatgcctact tatctgttgt ggaagccttg aaacattctg
     7201 gttatgccaa tgataccgca attgacctaa aatgggtcaa tgctaacgat gtgacggtgg
     7261 ataatgcagc tgacttgttg ggagatgcgg atgggattat tgtaccaggt ggttttggtc
     7321 aacgtggtac agaaggcaag atccaagcga ttcgctatgc ccgcgaaaat gatgtgccaa
     7381 tgcttggtat ctgtcttggc atgcagttga cttgtgttga atttgcccgc catgtcctca
     7441 atatggaagg tgcaaactct tttgagttag agccaagtac taaatacccc atcattgata
     7501 tcatgcgtga tcaaattgat attgaagata tgggaggtac gcttcgtctt ggattgtacc
     7561 catgtaaatt gaaaccaggt tcaaaagcag caatggctta caataatcaa gaggtggtgc
     7621 aacgtcgtca tcgtcaccgt tatgagttca acaacaaatt ccgtccagaa tttgaagcag
     7681 ctggttttgt tttctcaggg gtatcacctg acaaccgctt agttgaaatt gtagaattga
     7741 aagagaaaaa attctttgta gcagctcaat accacccaga attgcaaagc cgtccaaatc
     7801 gtcctgagga gctatacacc gcttttgtta cagctgctat taaaaatagc aattagtggt
     7861 tttaagggta agtttgtggc attctgcttg gctggcagat actgataaag attactagct
     7921 attagaggga tcttttctat aaaaatagca ttagaaaaag aaaaacgtga tatttttagg
     7981 ttagcacttt ctttttcagt catttttttg taaaatactt ggtatgaaaa ctattcgaat
     8041 agcaaagtat ttaggaattc tattcctttt gataactctt attagcgtag gtgctagttt
     8101 ttatttcttt catgttgcac aaataagaga agagaaatcg tttattaata ataagaaacg
     8161 gagtacaaat aatccattat acccagctga acagtctttt gacgctttac cttacgaaaa
     8221 acgtcaacta acaaatcgtg ggttaaaaca agtggggtgg tacttaccag ctgctcaaaa
     8281 aacaaaaaag acagctattg ttgttcatgg ttttacgaat gacaaagaag atatgaagcc
     8341 atatgctatg ctttttcatg atttgggcta taatgtctta atgccagaca atgaggccca
     8401 tggggaaagt gaagggaact tgattggtta tggctggaat gaccgcctta atgtcatggc
     8461 ttggacagac caactaatta aggaaaaccc tgaaagccaa atcacactct ttggcttatc
     8521 tatgggtgct gcaacagtaa tgatggcaag tggtgagcga ttgcctgcgc aagtcacctc
     8581 cctcatcgaa gattgcggtt ataccagtgt ttgggacgaa ttgaagtttc aggccaaggc
     8641 tatgtacaac ttacctgcct ttcctttact ctatgaagtc tctgccttat ctaagattcg
     8701 agcaggtttt agttacggag aagcgagctc agtgaaacag ctggctaaaa ataaacgtcc
     8761 aactttattt atccacggtg ataaggatga ttttgttcct acaaaaatgg tttatgacaa
     8821 ttataaggcc acgaaaggtc ctaaggaaat cttgattgtt aaaggggcaa aacacgccaa
     8881 atcctttgaa acaaacccag aacaatacca gaaaaaaatt gccgcttttt tgaaaaaagt
     8941 tgagaaataa gtattgacag ttaaactcac agttgctata ataatttatg ttgctgatga
     9001 gtagcgggg
//
LOCUS       DAXMQE010000055         8895 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.055, whole genome shotgun sequence.
ACCESSION   DAXMQE010000055 DAXMQE010000000
VERSION     DAXMQE010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8895)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8895)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8895
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.055"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            236..1480
                     /locus_tag="ACF4ZO_001751"
     CDS             236..1480
                     /locus_tag="ACF4ZO_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HFD5487260.1"
                     /translation="MKIVQGVQLHLIKTKQFKTNHITFRFSGDLNQKTVAKRVLVAQM
                     LATANECYPTVRQFREKLARLYGASLSTNVLTKGLVHIVDIDITFIQDRYACNGEKIL
                     DEMIQFLKDILFSPLLSIAQYQPKVFETEKNNLINYIESDREDSFYYSSLKVKELFYC
                     NKNLQMSEYGSPELIAKETAYTSYQEFHKMLNEDQIDIFILGDFDDYRVVQLIHQFPL
                     DNRNKNLNFFHLQNSVNIIKESIEKRAVHQSILQLAYHFPSVFGQRDYYALVLLNGLL
                     GSFSHSRLFIKIREEEGLAYSIGCRFDSYTGLFEIYTGIDSQHRTKTLQLIIQELNDI
                     KMGRFSEQLIKKTRLMLLNNALLSEDYNKNIIERIYTSSYIDSSYSIKNWIKGVNEVN
                     KADIIKVANLLKLQTVYFLEGI"
     gene            1482..2771
                     /locus_tag="ACF4ZO_001752"
     CDS             1482..2771
                     /locus_tag="ACF4ZO_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HFD5487261.1"
                     /translation="MTKLVKINYPNIDEDLYYVKLENGLTVYFIKKIGFLEKTAMLTV
                     GFGSLDNKLTVDDESRDAPAGIAHFLEHKLFEDESGGDISLKFTQLGAETNAFTTFNQ
                     TSFFFSTASKFQENLELLQYFVLSANITDESVSREKKIIGQEIDMYQDDADYRAYSGI
                     LQNLFPKTSLANDIAGSKESIQKITKILLETHHTYFYQPTNMSLFIVGDIDIDETFLA
                     IQRFQTTLSYPDRKRVTVDPLHYYPVIKSSSVDMDVTTAKLVVGFRGYLTLTQHSLLT
                     YRIALKLFLSMLIGWTSKIYHTLYEDGKIDDSFDVDVEIHHNFQFVLISLDTPEPIAM
                     SNYIRQKLATIKISKEFTNEHLNLLKKEMYGDFIQSLDSIEHLTHQFSLYLSDSDKET
                     YFDIPKIIERLTLKDVVTIGKAFFEKADASDFTVFPK"
     gene            2821..3846
                     /locus_tag="ACF4ZO_001753"
     CDS             2821..3846
                     /locus_tag="ACF4ZO_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD5487262.1"
                     /translation="MSEKSLGEVLRESRVGKNITLDDIELKTGISSHYLLAMELDQFK
                     IIPEEKFDQFLKEYADIVELDFNTLKRRYRYQVNSKKDSDIKSVTEIVEEKLSKKRLQ
                     EKLLSHQSMGDGQPLEVSKNKETLVIPVKTVGLDSKLPLKTISPVSQFKSDNRLIPKK
                     NVSRMKRNSTDSRSKTSLFPIAILGTIAFAIISVIILGVWQQFEKSQRAKEAEVALLK
                     ASEQSTNGLKNNSNDRKTQVTTEGSGNYLIATVTKSKETVDISVSLTEAQSSWISLTN
                     SEIGEGGITLTQDSPTYTATLPAEITESLLTLGVTNGVSVTIDGQPVDLSPLTSTDLS
                     YITFKIQ"
     gene            3860..4402
                     /gene="pgsA"
                     /locus_tag="ACF4ZO_001754"
     CDS             3860..4402
                     /gene="pgsA"
                     /locus_tag="ACF4ZO_001754"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003090075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008444 -
                     CDP-diacylglycerol-glycerol-3-phosphate
                     3-phosphatidyltransferase activity [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HFD5487263.1"
                     /translation="MIKKENIPNLLTLVRIAMIPFFLFITSSSNKVGWHIFAAVIFAI
                     ASFTDYLDGYLARKWHVVSNFGKFADPLADKMLVMSAFIMLVGLGLVPAWVSAVIICR
                     ELAVTGLRLLLVETGGKVLAAAMLGKIKTATQMLSIILLLCHWIFLGNVLLYIALFFT
                     IYSGYDYFKGASFLFKDTFK"
     gene            4404..5243
                     /locus_tag="ACF4ZO_001755"
     CDS             4404..5243
                     /locus_tag="ACF4ZO_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HFD5487264.1"
                     /translation="MSAIIELKKVTFNYHKDQEKPTLDGVSFHVKQGEWLSIIGHNGS
                     GKSTTIRLIDGLLEPESGSIIVDGDLLTITNVWEIRHKIGMVFQNPDNQFVGATVEDD
                     VAFGLENKGIAHEDIKERVNHALELVGMQNFKEKEPARLSGGQKQRVAIAGAVAMKPK
                     IIILDEATSMLDPKGRLELIKTIKNIRDDYQLTVISITHDLDEVALSDRVLVMKDGQV
                     ESTSTPEQLFARGDELLQLGLDIPFTTSVVQMLQEEGYPIDYGYLTEKELENQLCQLI
                     SKM"
     gene            5219..6061
                     /locus_tag="ACF4ZO_001756"
     CDS             5219..6061
                     /locus_tag="ACF4ZO_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HFD5487265.1"
                     /translation="MSINLQNVSYTYQAGTPFEGRALFNINLDILDGSYTAFIGHTGS
                     GKSTIMQLLNGLHVPTTGIVSVDKQDITNHSKNKEIKSIRKHVGLVFQFPESQLFEET
                     VLKDVAFGPQNFGVSPEEAEALAREKLALVGISENLFEKNPFELSGGQMRRVAIAGIL
                     AMQPKVLVLDEPTAGLDPKGRKELMTIFKKLHQSGMTIVLVTHLMDDVANYADFVYVL
                     DKGKIILSGKPKTIFQQVSLLEKKQLGVPKVTKLAQRLVDRGIPISSLPITLEELREV
                     LKHG"
     gene            6054..6854
                     /locus_tag="ACF4ZO_001757"
     CDS             6054..6854
                     /locus_tag="ACF4ZO_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HFD5487266.1"
                     /translation="MDKLILGRYIPGDSLIHRLDPRSKLLAMIIYIVIIFWANNVVTN
                     LLMLTFTLAVVFLSKIKLSFFLNGVKPMIGIILFTTLFQMFFSQGGKVIFSWWFISIT
                     DLGLSQAILIFMRFVLIIFFSTLLTLTTTPLSLSDAVESLLKPLTRFKVPAHEIGLML
                     SLSLRFVPTLMDDTTRIMNAQRARGVDFGEGNLIQKVKSIIPILIPLFASSFKRADAL
                     AIAMEARGYQGGEGRTKYRQLDWQLKDSLAIGIVSLLGLLLFFLKTSL"
     gene            7225..7839
                     /locus_tag="ACF4ZO_001758"
     CDS             7225..7839
                     /locus_tag="ACF4ZO_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase SLT domain-containing protein"
                     /protein_id="HFD5487267.1"
                     /translation="MFKKENLKQRYFNFGLVALALTILAIIFAFSSKNADTKSYAKKS
                     ESKMVTIDKAPKNNHAITKEESKEKAKSIASEPIPTVENSVAPTVTEEAPVIQQEVTQ
                     TVQQVSSVAYNPNNVVLSNGNTAGIVGSQAAAQMAAATGVPQSTWEHIIARESNGNPN
                     AANASGASGLFQTMPGWGSTATVEDQVNAALKAYSAQGLSAWGY"
     gene            complement(8253..>8895)
                     /gene="sdaAA"
                     /locus_tag="ACF4ZO_001759"
     CDS             complement(8253..>8895)
                     /gene="sdaAA"
                     /locus_tag="ACF4ZO_001759"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006565 - L-serine catabolic process
                     [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HFD5487268.1"
                     /translation="YIKKGNSLSDTTILNAVRNAIAVNELNAKMGLVCATPTAGSAGC
                     LPAVLATAIEKLDLSEKKQLEFLFTAGAFGLVIGNNASISGAEGGCQAEVGSAAAMSA
                     AALVKAAGGTSHQASQAIAFVIKNLLGLVCDPVAGLVEVPCVKRNALGASFALVAADM
                     ALADIESQIPVDEVIDAMYQVGSAMPTAFRETAEGGLAATPTGRRYSVEIFGE"
BASE COUNT         2989 a         1420 c         1603 g         2883 t
ORIGIN      
        1 aaattatttt agtaaacttt tccaagagtt ttatctaatt ttatgaaaaa aatagatata
       61 ttttgatttt taaaaaatat caagaaatat gataactggt aaaggatata ttgtagaaaa
      121 ctatatttta ctaacactaa aatcccgaca attaagtcaa aaaaagttat cactcaccta
      181 acctgaataa aaatggtata atcgtaagga tcacactatt tattaaggaa acattatgaa
      241 aattgttcag ggagtacaac ttcatctgat taagaccaaa cagtttaaaa ccaatcatat
      301 tacctttcgt ttttcaggtg atttgaacca aaaaacagta gcaaaaagag tcttagtggc
      361 acagatgtta gcaacagcta atgagtgtta tccaactgtt aggcagttta gagaaaaatt
      421 agcacgactt tatggagcta gcttgtcaac taacgtgtta acaaaagggt tagttcatat
      481 tgtggatatc gatattactt ttattcaaga tagatatgct tgcaatgggg aaaaaatact
      541 agatgaaatg attcagtttt taaaagatat cttgttctca cccctattat ccatcgccca
      601 gtatcagcct aaagtttttg agactgaaaa aaataatttg attaactaca tcgagtcaga
      661 tagagaggat tctttttact acagctctct taaggtaaaa gaattgtttt attgtaataa
      721 gaatctacaa atgtcagaat atggtagccc agaactaatt gcaaaagaga ctgcctatac
      781 tagctatcaa gaatttcata aaatgctcaa tgaagatcag attgatattt tcattttagg
      841 agattttgat gattatcgcg ttgttcagct aattcatcaa tttccacttg ataaccgaaa
      901 taaaaatcta aatttctttc atttacaaaa ttctgtcaat attattaaag aatctattga
      961 aaaaagagca gttcatcaat ctattttaca attagcttat cacttccctt cagtttttgg
     1021 acaacgtgac tattatgctt tagttctttt aaatgggttg ttaggctctt tttcacattc
     1081 ccgtctcttt ataaaaatta gagaagaaga aggacttgct tatagtatag ggtgtcgttt
     1141 tgatagttat acaggtttat ttgaaattta tactggaatt gacagtcaac atcgcactaa
     1201 aacgttacaa ctaatcatcc aagaattaaa tgacattaaa atgggacgat tctcagaaca
     1261 attgattaaa aagaccaggt tgatgttgtt gaataatgcc ttattatcag aagattataa
     1321 taaaaatata attgaaagaa tatacacatc ttcttacatt gattcttctt attctattaa
     1381 aaattggatt aaaggggtta atgaagttaa taaagcggat atcattaaag tagctaatct
     1441 tttaaagctt caaactgtct attttttaga aggaatataa aatgacaaaa ttagtaaaga
     1501 taaactatcc taatattgac gaagaccttt actatgtaaa attagaaaat ggtttaactg
     1561 tttattttat aaaaaaaata gggtttttag aaaaaacagc tatgttgaca gtaggtttcg
     1621 gttctcttga caataagttg acagtcgatg acgaatcacg agatgctcca gcaggtattg
     1681 cacacttttt agaacataaa ctctttgaag atgaatcagg tggagatatt tcattaaagt
     1741 ttacacaact aggagcagag acaaatgcct ttacaacttt caaccaaacg agtttcttct
     1801 tttcaacagc tagtaaattt caggaaaatt tggaactcct tcaatatttt gttctttctg
     1861 ctaatataac agatgaatct gttagtagag aaaaaaaaat aatcgggcaa gaaattgata
     1921 tgtatcaaga tgatgctgac taccgtgcat atagtggaat ccttcagaac ttatttccaa
     1981 aaacaagttt agctaatgat attgctggct caaaagaatc cattcagaag atcacgaaaa
     2041 tattattgga aacgcatcat acttattttt accaacctac taatatgagt ctattcattg
     2101 tcggtgatat tgatattgac gaaacttttt tagctattca aaggtttcaa accacattat
     2161 cctatccaga tagaaaaagg gtaactgttg atcctttaca ctactatcct gttattaaat
     2221 catcttctgt tgacatggat gttactactg ctaagctggt tgttggtttt cgagggtatc
     2281 tgaccttaac tcagcattca ctattaacgt atcgtattgc cttgaagcta tttttatcaa
     2341 tgcttatagg ttggacttct aaaatctatc atacgctata tgaagatggt aaaatagacg
     2401 attcatttga tgtggatgtt gaaattcatc ataattttca atttgtatta atatcacttg
     2461 atacaccaga gcctatcgca atgtctaact atatccgtca aaaattagcc actataaaga
     2521 tatcaaaaga gtttacaaat gagcacttaa atctattaaa aaaagaaatg tatggtgact
     2581 ttattcagag tttagactcg atagaacatt taacccatca gttcagtcta tacctgtctg
     2641 attctgataa agaaacatat tttgatattc caaaaattat agaaagactc actctaaaag
     2701 atgttgttac aattggaaaa gcattttttg aaaaagctga tgcttcagac ttcacagtct
     2761 tcccaaaata gatgaaaatc tgttataata gggttactat attatttttg aggtacctgt
     2821 atgagtgaaa aaagtcttgg tgaagtgtta agagaatcgc gtgttggaaa aaatatcaca
     2881 ctagatgata tagaattgaa gacagggatt tcttcccatt acttgctggc aatggaattg
     2941 gatcagttta aaattattcc ggaagaaaaa tttgatcaat ttttaaaaga atatgctgac
     3001 attgttgagt tagatttcaa tactttaaaa agacgatacc gttatcaagt taattccaaa
     3061 aaagacagtg atataaaatc tgtaactgag attgttgaag agaagttaag taagaaacga
     3121 ttacaagaga agttgttatc acatcagagc atgggggatg gtcaaccgtt agaagtttct
     3181 aagaacaaag aaaccttagt tatccctgta aagactgttg gtttagatag caaattgcca
     3241 ctaaaaacga tatcgcctgt tagccaattt aaatcagata acaggttaat tcctaaaaaa
     3301 aatgtgtcac gtatgaagcg aaatagcact gacagtcgtt ctaaaacgtc actatttccc
     3361 atagctatat taggaacgat tgcttttgca attatcagtg ttatcatttt aggtgtttgg
     3421 caacaattcg aaaagagtca aagggctaaa gaagctgaag ttgctttgct taaagcctct
     3481 gaacagtcta ctaacggttt aaaaaataat tcaaatgatc gcaaaactca agtcacaact
     3541 gaggggtcgg gtaattattt aatagcgact gttactaaat ctaaagagac cgttgatatc
     3601 agtgtgtctt taaccgaggc acaaagtagt tggatttctc taacaaattc agaaattggt
     3661 gaaggtggta taacattgac tcaagactcg ccaacttata cagcgacctt acctgcagaa
     3721 ataacagaat cattgttgac gcttggtgtg acaaatggtg tatctgtaac aattgatgga
     3781 caacctgttg atctatcacc tttaacaagt actgacttaa gttatatcac gtttaagatc
     3841 caataattaa ggtagactaa tgataaaaaa agaaaatatt cctaatctat taactcttgt
     3901 tcgaatcgca atgattcctt tctttctttt tattacttcc tcatctaata aggtggggtg
     3961 gcatattttt gcagctgtga tttttgcaat tgccagtttt accgattatc tagatgggta
     4021 tcttgcgcgt aagtggcatg tagtcagtaa ttttggaaag tttgccgatc ctctagcaga
     4081 taagatgctt gtcatgagtg cctttatcat gttagttgga cttggcttag ttcctgcgtg
     4141 ggtatcagct gttattattt gccgagaatt ggcagtaact ggtcttcgat tactacttgt
     4201 tgaaaccgga ggaaaggtcc ttgcagctgc tatgctggga aaaatcaaaa cagcgacaca
     4261 aatgttgtct attattttat tactttgcca ttggatattc ctaggaaacg tcttactcta
     4321 tattgctctt tttttcacta tttattctgg atatgattat tttaaaggag caagctttct
     4381 ttttaaggat acgtttaaat aacatgtcag ctattattga acttaaaaaa gttacattta
     4441 attaccataa agaccaagaa aaaccaacat tagatggcgt atcgtttcat gtgaaacaag
     4501 gtgagtggct gtctatcatt ggccataacg gatctggtaa atcaacgact attcggttaa
     4561 ttgatggatt attggaacca gaatcagggt ctattattgt tgatggagat ctactaacca
     4621 taactaatgt ttgggaaatt cgtcataaaa ttggtatggt ctttcaaaac cctgataatc
     4681 agtttgttgg agcaactgtt gaagatgatg ttgcttttgg gcttgaaaat aaaggtattg
     4741 cacatgaaga tataaaagag agggttaatc atgctttaga gttagtcggc atgcagaact
     4801 ttaaagaaaa agaaccagcc cgtttatctg gtggccaaaa acagcgcgta gctattgcag
     4861 gtgcagttgc tatgaagcct aaaattatta ttttagatga agccactagt atgcttgacc
     4921 ctaaaggacg attagagtta attaaaacta taaaaaacat ccgtgacgac taccagctga
     4981 ctgttatttc cattactcat gacttagatg aagttgctct tagtgataga gttttagtga
     5041 tgaaagatgg tcaagtggaa tcaacatcaa caccagaaca attatttgca agaggggatg
     5101 aactactcca attaggtctt gatatccctt ttacaacatc tgttgtacag atgcttcaag
     5161 aagaaggtta tcctattgac tatggatatc tcacagaaaa ggaattagaa aatcagttat
     5221 gtcaattaat ctccaaaatg taagttatac ttatcaagca gggactcctt ttgaagggcg
     5281 tgcccttttt aacattaatt tagatatttt agatggttct tatacggctt ttatcggaca
     5341 tactggatcc gggaaatcga ctattatgca attgctaaat ggtttacacg ttccgacaac
     5401 gggaattgtc agcgtagata aacaagatat aacgaatcac tctaaaaata aagagattaa
     5461 atctattcga aaacatgtag gattagtttt tcaatttcca gaaagtcaac tatttgaaga
     5521 gacagttttg aaagatgttg cttttggccc tcaaaatttt ggggtctctc cggaggaagc
     5581 agaagcttta gcgcgtgaaa aactagctct tgttgggatt tcagaaaatc tttttgaaaa
     5641 gaatccattt gaactctcag ggggtcaaat gcgtcgtgtt gctattgcgg gtatccttgc
     5701 tatgcagcca aaggttttag ttttagatga accgactgct ggtcttgatc ctaaagggcg
     5761 taaagaatta atgactattt ttaaaaagtt acaccaatct ggcatgacta ttgttttagt
     5821 aacccatctg atggatgatg tggccaatta cgcagatttt gtatatgttc ttgacaaagg
     5881 taaaattatt ttatcaggaa aaccaaaaac aatttttcaa caagtcagtt tgcttgagaa
     5941 aaaacagtta ggagttccta aggtgactaa acttgctcaa aggcttgttg atagaggaat
     6001 acctatctct tctttgccta ttaccttaga ggagctaaga gaggtactaa aacatggata
     6061 agctgattct tggtcgttat attcccggag attctctcat tcatcgtctt gacccaagaa
     6121 gtaaattatt agcgatgatt atttatattg tcattatctt ttgggctaac aatgttgtga
     6181 caaatttgtt gatgttgact tttactttag cagttgtttt tttgtcaaaa atcaagttgt
     6241 ctttcttttt aaatggggtt aaaccaatga ttggtattat cctcttcacg actttatttc
     6301 agatgttttt ctcacaagga ggaaaagtaa tttttagttg gtggttcatt agcataactg
     6361 atttaggatt gagccaagct attttaattt ttatgcgttt cgttctaatt attttctttt
     6421 caacgctgtt aacgttgacg acaacacctt taagcctatc tgatgcagtt gaatcattat
     6481 taaaaccttt aacaagattt aaagttccag ctcacgagat cggactaatg ctttctttaa
     6541 gtttacgttt tgtgcctact ttaatggatg ataccacgcg tattatgaat gcacaaaggg
     6601 cccgtggagt tgattttgga gagggaaatt taattcaaaa agttaaatcc attattccta
     6661 ttttaatccc tcttttcgct tcaagcttta aaagagccga cgcattagct attgctatgg
     6721 aagctagagg ttatcaggga ggagaagggc gaactaaata tcgtcaatta gactggcagc
     6781 taaaagatag tttagctatt ggaatagttt ctttattggg tttgctactt tttttcttga
     6841 aaacctcttt gtaatatttt ttagcacaaa acttttcttt attataagaa atgaattgta
     6901 cctcaaaagt tagatacaac atctaatgat tgaggtactt ttcttcattt gaggaattga
     6961 aaaccgctat ctcaactata ttaatcatcc caacaataac aaatcgaacg aaatctaaaa
     7021 ggactgagtc ctgttcaata cagaactaaa ttcttagttt aatgatatta tcccgctttt
     7081 taatatcgct aagaagaaga gttttatgat tttttacaac ttcttataat atcaatgtag
     7141 ttgtaatatt tttaatatat cttcaataac gaggtaataa ttaaaagata ttatggataa
     7201 cggagaaaag tgaggtatta ttgaatgttt aagaaagaaa atttaaaaca acgttatttt
     7261 aattttggat tagtagcgtt agctctaaca atattagcca tcatttttgc cttctcaagt
     7321 aaaaatgctg atactaagtc ttatgctaag aagtcagaaa gtaaaatggt aacaatcgac
     7381 aaggctccaa aaaataatca tgctattact aaagaagaaa gcaaagaaaa agcaaagagc
     7441 attgcttcgg agcctattcc cacagtagaa aactctgtag ctccgacagt aacagaggaa
     7501 gcaccggtta ttcagcaaga agtgactcaa actgttcagc aggtatcttc agtagcctat
     7561 aatccaaata atgtggtact ttccaatgga aatactgctg gtattgtagg aagtcaagcg
     7621 gcggcacaga tggcagcagc aacaggtgtt ccacaatcaa cttgggaaca tataattgcg
     7681 cgtgaatcta atggaaatcc taacgcagct aatgcttctg gggcatcagg gttgttccag
     7741 acaatgccag gttggggttc tacagcaacg gttgaagatc aagtcaatgc agccttgaaa
     7801 gcctatagtg cacaaggttt atcagcttgg ggttactaaa taaacatagc tggaagaaat
     7861 aaaacctatt gttagtattt actaacaata ggtttttggt atttaattgt ctttatgatt
     7921 tgtagtgatg aattagtctc aaaacaaaac attgccttat cagggaatat agctcgtatt
     7981 atttaggaaa actgaccagc acttaagtac ctctgatatt taaggcagtt atactgataa
     8041 caagcaggaa aaaaactctt aaatgtttat aaggtcatta gcaattttca gtattttaca
     8101 ctactacact tttgagtttc aacaatttac taggagttgt ttctaagggg aaacaacata
     8161 gcttgatagc tatctattag ttattttagt gaatatatag cagaaaaata aaacgctttc
     8221 aaatatttct aagaattttt ctacctatct atttattcgc caaatatttc tacgctgtaa
     8281 cgtcgtccag ttggagtagc ggctaaacca ccttctgctg tttcacggaa agcagttggc
     8341 atggcagagc cgacttgata catagcatca ataacttcgt caacaggaat ttgagattca
     8401 atatcagcta aagccatatc agctgcgaca agggcgaaac ttgctcctag ggcattgcgt
     8461 ttgacacaag gcacttctac taggccggca acaggatcac agacaagtcc taataaattt
     8521 ttgataacaa acgcaatagc ttgactagct tgatgagatg ttccaccagc tgctttaaca
     8581 agagcagctg cactcatagc agctgcagaa ccaacttctg cttggcatcc accttctgca
     8641 ccagaaatag aggcgttatt tccaataaca agaccaaaag ctcctgcagt aaataaaaac
     8701 tctaattgtt ttttttctga taagtcaagt ttttcaatag ctgttgcgag cactgctggt
     8761 aagcatcctg cacttcctgc agtgggtgtt gcacagacaa gtcccatttt agcatttaat
     8821 tcgtttacag ctatagcatt tctaacagca ttaagaatag tagtatcaga aaggctgttc
     8881 ccttttttaa tgtag
//
LOCUS       DAXMQE010000056         8502 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.056, whole genome shotgun sequence.
ACCESSION   DAXMQE010000056 DAXMQE010000000
VERSION     DAXMQE010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8502)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8502)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8502
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.056"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            233..310
                     /locus_tag="ACF4ZO_001760"
                     /pseudo
     CDS             233..310
                     /locus_tag="ACF4ZO_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(599..3016)
                     /gene="hylA"
                     /locus_tag="ACF4ZO_001761"
     CDS             complement(599..3016)
                     /gene="hylA"
                     /locus_tag="ACF4ZO_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronidase"
                     /protein_id="HFD5487269.1"
                     /translation="MNTYFCTHHKQLLLYSNLFLSFAMMGQGTAIYADTLTSNSEPNN
                     TYFQTQTLTTTDSEKKVVQPQQKDYYTELLDQWNSIIAGNDAYDKTNPDMVTFHNKAE
                     KDAQNIIKSYQGPDHENRTYLWEHAKDYSASTNITKTYRNIEKIAKQITNPESCYYQD
                     SKAIAIVKDGMAFMYEHAYNLDRENHQTTGKENKENWWVYEIGTPRAINNTLSLMYPY
                     FTQEEILKYTAPIEKFVPDPTRFRVRAANFSPFEANSGNLIDMGRVKLISGILRKDDL
                     EISDTIKAIEKVFTLVDEGNGFYQDGSLIDHVVTNAQSPLYKKGIAYTGAYGNVLIDG
                     LSQLIPIIQKTKSPIEADKMATIYHWINHSFFPIIVRGEMMDMTRGRSISRFNAQSHV
                     AGIEALRAILRIADMSEEPHRLALKTRIKTLVTQGNAFYNVYDNLKTYHDIKLMKELL
                     SDTFVPVQKLDSYVASFNSMDKLALYNNKHDFAFGLSMFSNRTQNYEAMNNENLHGWF
                     TSDGMFYLYNNDLGHYSENYWATVNPYRLPGTTETEQKPLEGTPENIKTDYQQVGMTS
                     LSDDAFVASKKLNNTSALAAMTFTNWNKSLTLNKGWFILGNKIIFVGSNIKNQSSHKA
                     YTTIEQRKENQKHPYCSYVNNQPVDLNNQLVDFTNTKSIFLESDDPAQNIGYYFFKPT
                     TLSISKALQTGKWQNIKADDKSPEAIKEVSNTFITIMQNHTQDGDRYAYMMLPNMTRQ
                     EFETYISKLDIDLLENNDKLAAVYDHDSQQMHVIHYEKKATMFSNHNLSHQGFYSFPH
                     PVKQNQQ"
     gene            3248..4237
                     /locus_tag="ACF4ZO_001762"
     CDS             3248..4237
                     /locus_tag="ACF4ZO_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007893175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HFD5487270.1"
                     /translation="MKYIVNKSHNPAFNIALEAYAFRELVEEDELFILWINEPAIIIG
                     KHQNTIQEINKEYIDEHGIHVVRRLSGGGAVYHDLNNLNYTIISNKTAEGAFDFKTFS
                     QPVIATLADLGVTANFTGRNDIEIDGKKICGNAQAYYKGRMMHHGCLLFDVDMTVLGD
                     ALKVSKDKIESKGVKSVRARVTNILNELPEKITVEEFSDKILAKMKETYPDMTEYVLS
                     EDELAKIEQSAKEQFGSWDWTYGKAPEYTIERNVRYPAGKISTFANVENSIIKNLKIY
                     GDFFGIKDVQDIENLLIGCKYEYRDVFEHLKTIDTTQYFSRMTVEEVAKAIVS"
     gene            complement(4346..5137)
                     /gene="gatD"
                     /locus_tag="ACF4ZO_001763"
     CDS             complement(4346..5137)
                     /gene="gatD"
                     /locus_tag="ACF4ZO_001763"
                     /EC_number="6.3.5.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_function: GO:0140282 - carbon-nitrogen ligase activity
                     on lipid II [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipid II isoglutaminyl synthase subunit GatD"
                     /protein_id="HFD5487271.1"
                     /translation="MTYTSLKSPENQDYIYDLNIAHLYGNLMNTYGDNGNILMLKYVA
                     EKLGARVTVDIVSINDTFEQDDYDIVFFGGGQDYEQSIVAKDLPSKKAALADYIANNK
                     VALAICGGFQLLGQYYVQANGVKIDGLGIMGHYTLNQHQNRFIGDIKIHNDEFNETYY
                     GFENHQGRTFLSGDEKPLGRVVYGNGNNKEDQTEGVHYKNVYGSYFHGPILSRNVNLA
                     YRLVTTALKKKYGSAISLPSYDDILKQEITEEYADLKSKASFNKV"
     gene            complement(5137..6480)
                     /gene="murT"
                     /locus_tag="ACF4ZO_001764"
     CDS             complement(5137..6480)
                     /gene="murT"
                     /locus_tag="ACF4ZO_001764"
                     /EC_number="6.3.5.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016881 - acid-amino acid ligase activity
                     [Evidence IEA];
                     GO_function: GO:0140282 - carbon-nitrogen ligase activity
                     on lipid II [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipid II isoglutaminyl synthase subunit MurT"
                     /protein_id="HFD5487272.1"
                     /translation="MKMKTLLGIIAGKAAQSILTKLGRGSTYPGRLALACDKDILKDL
                     SKDYDIVVVTGTNGKTLTTALTVGILKEAFGEIITNPSGANMITGITSTFLAAKKGKS
                     GRQIAVLEIDEASLPRITTYLKPSLFVYTNIFRDQMDRYGEIYTTYQMIVDGARNAPK
                     ATILANGDSPIFSSKDIVNPVQYYGFDTAKHAPQLAHYNTEGILCPKCEHILQYRLNT
                     YANLGDFICLNCGFKRPQLDYRLTELTTITNHSSEFIIDGQDYKINVGGLYNIYNALA
                     AVSVAEFFGVSPEKIKAGFNKSKAVFGRQETFTIGDKSCTLILIKNPVGASQALEMIQ
                     LADYPFSLSVLLNANYADGIDTSWIWDANFELITQMPITEINAGGVRHSEIARRLRVT
                     GFDDTKIKQAEKLEQIIETIEKQEAKHAYILATYTAMLEFRSLLADRHVVEKEMI"
     gene            6582..7433
                     /gene="cdaA"
                     /locus_tag="ACF4ZO_001765"
     CDS             6582..7433
                     /gene="cdaA"
                     /locus_tag="ACF4ZO_001765"
                     /EC_number="2.7.7.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004016 - adenylate cyclase activity
                     [Evidence IEA];
                     GO_process: GO:0006171 - cAMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diadenylate cyclase CdaA"
                     /protein_id="HFD5487273.1"
                     /translation="MNNLSSIDIKFLLSLFADPWLLAVHLLDILIVAYLIYRFIKALT
                     GTKIMSLVQGVIFFLVLRFIAEWIGFTTITYLMNQVITYGVIAGVVIFTPEIRAGLEK
                     FGRSTQVFLQKQYVSSESALVDALIKSVAYMGPRKIGALIAIEQTQTLQEYIATGIPL
                     NADISSQLLINIFIPNTPLHDGAVIVGQNKIVAACAYLPLSESKAISKEFGTRHRAAI
                     GLSENSDALTIIVSEETGAISVTRKGQFLHDLSTDEFETVLRTYLMSDSNVSLPWYKK
                     ILGGKSK"
     gene            7430..8386
                     /locus_tag="ACF4ZO_001766"
     CDS             7430..8386
                     /locus_tag="ACF4ZO_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HFD5487274.1"
                     /translation="MKRFLNSRPWLGMVSVFFAILLFLTAASSNHNNSSSQIYSPIET
                     YTHSLKDVPIDMKYDSDKYFISGYSYGAEVYLTSTNRIKLDSEVNNDTRNFKIVADLT
                     HSHPGTVSVNLRVENLPSGVTATVSPDKISVTIGKKESKVFPVRGSVDAKQIANGYEI
                     SKIETGVNKVEVTSDESTIALIDHVVAKLPDDQVLDRNYSSRVTLQAVSADGTILASA
                     IDPAKTNLSVAVKKITKSVPIRVEAVGMMDDSLSDIQYKLSKQTAVISGSREVLEDID
                     EIIAEVNISDVTKNTSKTVSLSSSQVSIEPSVVTVQLTTTKK"
BASE COUNT         2645 a         1435 c         1655 g         2767 t
ORIGIN      
        1 gcaccccaaa cgttagatat aaaaccctaa cgtttggggt gtttttgtat gacattaagc
       61 tatgaagata agctagacat ttagcgctaa aaaaaccgag agaactccgt ttgaaagaag
      121 catctctgaa aagaagaaga caaaaaacca ttataaagaa tggacaaaga cgagttctga
      181 ttagattttc ttttaaggac ggctaaattg actcgttcta cctactatta tcatcgatta
      241 ttgcaacaat aaacgtatca aaataaaacg aaaaggactt agtcctctac aacacagaac
      301 taaatccttt acttcaaata gagtagccaa cttttggggc tcagtgcagt ttccagtttt
      361 tttgtcttta ataacgtttc attgttaacc cttactttcc aataacagct aaatccttaa
      421 gtctttctta cgaaagggtt ttgtgatatg gttaaaagaa gcaactaaag ctccacctaa
      481 gaattctaaa gaggaggact gatacccaag tatgcggtaa gcgtcgttgt cttttgtggg
      541 gaattttatg agagttaaga gcattgtttt tagctgcaat tccttgatga gcaagctttt
      601 attgctgatt ttgcttgaca ggatgaggaa aactataaaa gccttgatga gaaagattat
      661 gatttgaaaa catcgttgct tttttttcat agtgaatgac gtgcatctgt tgactatcat
      721 gatcgtagac agcggccagt ttgtcattgt tttctaacaa gtcgatatca agcttgctaa
      781 tataggtttc aaattcttga cgagtcatat ttggaagcat catataggca taacgatcgc
      841 catcttgagt atggttttgc atgatagtga taaaggtatt tgaaacttct ttgatggctt
      901 ctggtgattt atcatcagct tttatgtttt gccatttccc tgtttgaagt gccttactta
      961 tgctaagtgt tgttggcttg aagaagtagt aaccaatatt ttgagcggga tcatcacttt
     1021 caaggaaaat acttttagtg tttgtaaaat caactagctg attattcaag tcaacgggtt
     1081 gattgttaac ataagaacag taagggtgct tttgattttc ttttcgttgt tcaatagttg
     1141 tatacgcctt gtgagatgat tggtttttga tattgctacc aacaaagatt attttgtttc
     1201 ctaagataaa ccacccttta ttgagagtga ggcttttatt ccaattagtg aaggtcatag
     1261 cagctagagc acttgtgtta ttaagttttt tacttgcaac aaaagcgtca tcagagagac
     1321 tagtcatgcc aacttgttga tagtccgttt taatattctc aggagttccc tctagtggtt
     1381 tttgctcagt ttctgtggtt ccaggtaagc ggtagggatt taccgttgcc caatagtttt
     1441 cactgtagtg tcctaaatcg ttattgtata ggtaaaacat tccatcagaa gtaaaccagc
     1501 catgaagatt ttcattattc atagcttcat aattttgagt tcgattcgaa aacattgata
     1561 ggccaaaagc aaaatcgtgt ttattattat atagtgccaa tttatccata ctattgaaac
     1621 tagctacgta actatcaagt ttttggactg gaacaaaagt atcacttagt agttctttca
     1681 taagtttgat atcgtgatag gttttcaaat tatcatagac attgtaaaaa gcattccctt
     1741 gtgtgacgag tgtttttata cgtgttttaa gtgccaaacg gtgaggctct tcagacatgt
     1801 cagcaatacg taaaatagca cgaagtgctt caatgccagc aacatgagat tgagcattaa
     1861 aacgactgat agaacgccct cgagtcatat ccatcatttc tccacgaacg atgataggga
     1921 aaaaagaatg gttaatccaa tgatagatag tagccatttt atccgcttct ataggagact
     1981 ttgttttttg aataatagga attaattgcg ataagccatc tataagcaca ttgccgtaag
     2041 ctccagtgta agcaatgcct tttttataaa gtggactttg agcgttagta accacgtgat
     2101 caattaaaga accgtcttgg taaaaaccat ttccttcgtc aactagcgtg aaaactttct
     2161 caattgcttt gattgtatca ctaatttcga gatcatcttt acgaagaata ccggaaatga
     2221 gtttaacacg ccccatatca attaaatttc cgctatttgc ttcaaaaggt gaaaaattgg
     2281 cagcgcgaac cctaaaacga gtagggtcag gcacaaattt ttcgattgga gctgtgtatt
     2341 taagaatttc ttcttgagta aaataaggat acatcaagga taaggtatta ttaatagcac
     2401 gaggagttcc aatttcataa acccaccaat tttctttgtt ttcttttcca gttgtttgat
     2461 gattttcacg atctagatta taagcgtgtt catacatgaa ggccataccg tcttttacaa
     2521 tagcaatagc tttactatct tgataatagc atgattcagg attagtgatc tgttttgcta
     2581 ttttttcaat attgcggtaa gttttcgtga tattagtaga agcggaataa tcctttgcat
     2641 gttcccaaag gtaagttcta ttttcgtggt caggcccttg atagctttta ataatgtttt
     2701 gagcatcctt ttcagcttta ttatgaaaag tgaccatgtc aggattggtt ttatcataag
     2761 catcgttgcc tgcgataata ctgttccatt ggtctaacaa ttcagtatag tagtcttttt
     2821 gttgtggctg tactaccttt ttttcgctat ctgtagtagt gagcgtttgc gtttgaaagt
     2881 aagtattatt aggttctgaa tttgaagtca gtgtatcggc ataaatggca gttccttggc
     2941 ccatcatagc aaagctaagg aataggtttg aataaagtag taattgttta tggtgtgtgc
     3001 aaaaataagt attcactgat aaattcctcc aatataaaaa tgagataata aaagtaaatt
     3061 ggtctactaa gtaaaaatat accacgttaa agtattttta taaaccctta cataaataat
     3121 ggctgagttt ttgtgcacta ataagtgtag gtactgaaga tgtcatacag ataggactct
     3181 tgtcttttat atttgttttc attatactag agaggtagat tacatttttg aaaggatttt
     3241 ttctcctatg aaatacatcg ttaacaaaag tcacaatcct gcctttaaca tcgctttgga
     3301 agcctatgct tttagagaac tggtggaaga agacgaattg tttatccttt ggatcaatga
     3361 gccagctatt attattggca aacatcaaaa caccattcaa gaaatcaata aagaatacat
     3421 tgatgaacat ggtattcatg ttgtgcgacg tttatctggt ggtggcgcgg tttatcatga
     3481 tttgaataac ttgaactaca ctatcatttc aaataaaaca gcggaaggcg catttgattt
     3541 caaaaccttc tcacaacctg tgattgcgac cttagctgac ttgggcgtaa cagccaactt
     3601 tacaggccgt aatgatattg aaattgatgg caaaaaaatc tgtggtaatg ctcaagctta
     3661 ctacaaaggt cgcatgatgc accatggttg ccttttgttt gatgtggata tgaccgttct
     3721 tggcgatgct cttaaggtaa gtaaggataa gattgagtct aaaggagtga agtctgttcg
     3781 tgcccgtgtg accaatattt taaatgaatt accagaaaaa attaccgttg aggaattttc
     3841 agataaaatc ttggccaaga tgaaagaaac gtatccagac atgacagaat atgtcttgtc
     3901 ggaggatgag ttggctaaga ttgaacaatc tgccaaagag caatttggta gctgggattg
     3961 gacctacggc aaagcgccag aatatacgat tgaacgcaat gttcgttacc ctgcaggtaa
     4021 aatttcaacc tttgcaaatg ttgaaaattc tatcattaaa aaccttaaaa tctatggtga
     4081 tttctttgga atcaaagatg tgcaagacat tgagaactta ttaattggtt gtaaatatga
     4141 gtaccgtgat gtttttgaac atttaaaaac gattgatacg actcagtact tctcacgcat
     4201 gaccgttgaa gaagttgcta aagctattgt ttcttagtgg ttttaatcac ttaagaagct
     4261 ctgtcagaag aaaaaactat aaaactccta agcgaaatat cgtgtcctgc ttaggagttt
     4321 ttgtttgatg acatgaaaga agaacttaaa ctttattaaa ggaagctttg cttttaaggt
     4381 cggcatattc ttcagtgatt tcttgtttca gtatatcatc atagctaggt agtgaaatag
     4441 ctgatccata ctttttttta agagctgttg ttactaagcg gtaagcaaga ttaacattgc
     4501 gtgataagat aggaccgtgg aaataactac catagacgtt tttatagtga acaccttcag
     4561 tttggtcttc tttattatta ccgttgccat aaaccactcg tccaagtggc ttttcgtcac
     4621 cagataagaa ggtacgtcct tgatgatttt caaagccata ataggtttcg ttaaattcgt
     4681 cattatgaat tttaatatct ccaataaagc gattttggtg ctgattaagg gtgtagtgtc
     4741 ccataattcc aagtccatca attttaaccc cattagcttg gacatagtat tgccctagta
     4801 attggaagcc accacagatg gcaagcgcca ctttattatt agcaatgtaa tccgctaagg
     4861 cagctttttt gctaggcaaa tccttggcaa caatgctttg ttcataatct tgaccaccac
     4921 caaagaaaac aatatcgtaa tcgtcttgtt caaaggtatc attgatagat acaatatcaa
     4981 cagtaaccct agctccaagt ttttcagcga catacttgag cattaaaata ttgccgttat
     5041 caccataagt attcataaga ttaccataga gatgggcgat attgaggtcg tagatgtagt
     5101 cttgattttc gggagatttt agtgaagtgt atgtcattag atcatctcct tttcaacgac
     5161 atggcggtca gcaagtaagc tacggaattc taacattgcc gtataggttg ctaaaatata
     5221 ggcatgctta gcttcttgtt tttcaatggt ttctatgatt tgctcgagct tttcagcttg
     5281 ttttatctta gtatcgtcaa atcctgtgac tctaagtctt ctagcaattt cagagtgacg
     5341 gacgccgcca gcattaattt ctgtaatagg catttgggta atgagttcaa aattagcatc
     5401 ccaaatccag ctggtatcaa tgccgtcagc gtaattagca tttaaaagca cagataagct
     5461 aaatgggtaa tcagctagct gaatcatttc aagcgcttga ctggctccaa caggattctt
     5521 gataaggata agggtgcatg atttatcacc aatagtaaaa gtttcttgtc ttccaaaaac
     5581 cgccttactt ttgttaaagc ccgccttgat tttctcggga gaaacaccga aaaattcagc
     5641 aacagagacg gcagcgaggg cgttgtaaat attatataag ccaccgacat tgattttgta
     5701 atcttggcca tcaatgataa actcagaact gtgattggta atcgtcgtga gttcagttaa
     5761 tcgataatcc aactgtggtc tcttgaagcc acaatttaaa caaataaagt ctcctagatt
     5821 cgcataagta ttgagacgat actgaagaat atgttcgcat tttggacata aaatcccttc
     5881 tgtgttgtaa tgagctagct gcggagcatg cttagcagta tcaaaaccat aatactgaac
     5941 tggattaact atgtccttag aagagaaaat aggactatct ccattggcta gaatagttgc
     6001 ttttggagca tttcgagcac catctacaat catctgataa gtagtgtaaa tctctccgta
     6061 gcggtccatc tgatccctaa aaatattagt ataaacaaaa agactaggtt ttaagtaagt
     6121 ggtaattcta ggaagactag cctcgtcaat ttctaaaaca gcaatttgcc ttccagattt
     6181 ccctttttta gcagctaaaa aagtagaagt aattccagta atcatattgg caccacttgg
     6241 atttgtgatt atctcgccaa atgcctcttt caaaataccg acagtaagag cagttgttaa
     6301 cgttttacca ttagtaccag tgacgaccac aatatcatag tctttagaca aatcctttaa
     6361 aatatcttta tcacaagcta gagccaatcg accaggataa gtagatcctc gccctagttt
     6421 tgttaaaatg gattgagcag ctttgccagc aataatgccg agtaatgtct tcattttcat
     6481 gcttatattt tatcataagt ttattgattt tagataggga aaaatctttg atcatgatat
     6541 aatatagcta ataacttttt tgatatagaa atgagagttg tatgaataat ttatctagta
     6601 tcgatattaa atttttatta agcttatttg cggatccttg gctgctggca gtgcatcttt
     6661 tagatattct aattgttgcc tatttgattt atcgttttat taaagcattg actggaacta
     6721 aaatcatgtc tttagttcaa ggggtcattt tctttttggt tcttcgtttt attgcagagt
     6781 ggattggctt tacgacaatc acatacttaa tgaaccaagt cattacttat ggtgtaattg
     6841 caggagtagt catttttacc cctgaaattc gggcaggact ggagaaattt ggtcgttcta
     6901 cgcaagtttt tttacaaaaa cagtacgtca gcagtgaatc tgctttggtc gatgctttga
     6961 ttaaatctgt ggcctatatg ggtccacgca agataggtgc actgattgct attgaacaga
     7021 ctcaaacctt acaagaatat attgcgacag gaattccgct gaatgccgat atttcaagtc
     7081 aactactcat caatattttt attccaaata cgccgcttca tgatggagct gttatcgttg
     7141 gtcagaataa gattgtggca gcctgtgcct acttgccttt gtcagaatca aaggcaattt
     7201 ccaaagaatt tggaacccgt catagagcgg ctattggatt atctgaaaac tctgatgcac
     7261 taactatcat tgtttcagaa gaaacaggag ctatttccgt aactcgcaaa ggccaatttt
     7321 tacatgattt aagcacagat gaatttgaaa cggtacttag gacctacctg atgagtgatt
     7381 caaatgttag tttaccatgg tataagaaaa ttctaggagg gaaatctaaa tgaaacgatt
     7441 tttaaatagt cgtccttggt taggaatggt atcagtcttt tttgcgattc tccttttttt
     7501 aactgcagca tcgagcaatc ataataactc tagctcgcaa atttatagcc cgattgaaac
     7561 ctatacgcat agccttaaag atgtaccaat tgatatgaag tatgatagtg acaaatattt
     7621 tatcagtggg tattcttatg gtgcggaagt ttatctaacc tccactaatc gtatcaaatt
     7681 agattctgaa gtgaacaatg atacacgtaa ttttaagatt gtggcggatc taacacatag
     7741 tcatccaggt acagtaagtg tcaacctaag agtagaaaac cttccttctg gggtgacagc
     7801 taccgtatct ccagataaaa tatcagtcac aattggcaaa aaagaatcta aggtatttcc
     7861 tgttagagga agcgttgatg ctaaacaaat tgcaaatggt tatgaaatta gcaaaattga
     7921 aacgggggtt aataaggttg aagtgaccag tgatgaatct accattgctt taattgatca
     7981 cgttgtggca aagttacctg atgatcaagt gttagatagg aattatagta gtcgagtgac
     8041 cttacaagct gtctcagctg atggaactat tttagcaagt gcaattgatc ctgcaaaaac
     8101 aaatttatca gttgctgtaa aaaaaataac gaaatcagtc ccgattagag ttgaggcagt
     8161 ggggatgatg gatgatagct tatcagatat tcaatacaaa ttgtcaaaac aaacagctgt
     8221 tatctcaggt agtcgagagg tcttagaaga tattgatgaa attattgcag aagttaacat
     8281 ttctgatgtc actaaaaata ctagtaagac cgtgagtttg tcttctagtc aggtgtcaat
     8341 tgagccgtca gtagtgaccg ttcagttgac aaccaccaaa aaataatgga taataactag
     8401 gaaaattgaa tggaggaagc cattaggctt atataaatta tgggaaaata ttttggaaca
     8461 gatggtgttc gtggcgaagc aaatgttgag ctgacacctg ag
//
LOCUS       DAXMQE010000057         7982 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.057, whole genome shotgun sequence.
ACCESSION   DAXMQE010000057 DAXMQE010000000
VERSION     DAXMQE010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7982)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7982)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7982
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.057"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            complement(<1..1106)
                     /locus_tag="ACF4ZO_001767"
     CDS             complement(<1..1106)
                     /locus_tag="ACF4ZO_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFD5487275.1"
                     /translation="MKYNKTKYPNIFWYITLKGKRYYIRRGYYLNGEKKEATESGIKT
                     IQEARLLLAEIERKIENNEFAYNKNLTVDEYWDIYVDNRLKAGVWSPDTYVERTNIFK
                     NHISPKFGNKKMNAINRIEYENYINNLLNTNSRSTVKHIYDVFSIMLNHAVKNKMLDD
                     NIIKFIDIGDSEIKPINKRRSMQEFKAWDKVARKMLDDYDYAMVRITYLGLRRSEVAG
                     IKLGNITFNDKDCAVVKIDESRTRGRKDGGGLKTAYSERYVYLDFETSQLLKKAIDTS
                     IKIAVCNDRILNKADFLFLGDDEKVKPSFVGKPIGSHYIYCLFKKINKNCDVHFTPHM
                     MRHFFATQGQIAGVPIEHMAAALGHSNNYMTSQYT"
     gene            complement(1284..2705)
                     /locus_tag="ACF4ZO_001768"
     CDS             complement(1284..2705)
                     /locus_tag="ACF4ZO_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4041 domain-containing protein"
                     /protein_id="HFD5487276.1"
                     /translation="MKKSDGLPFYFRFWFILIIILLYPFTYGISILFGLGLFLQRQKT
                     YPNLTPSQQKKWNEIKESEIEASAIKNDAYERAAEIKNEASKIAIKTEEEAVKKFNTL
                     VSSGEAKKQNLENDIKSLSSQKKEIEFFIEENSDKSLLSQTTVDFTDNVTSNEIKNEL
                     SIVQLNEKELIKLGIAVNSLGATTKVNIAKQSKQLLRAFNAESDYYLSNITIKNVDTY
                     RNKLAKTFETLNKLFEIDGVKISKELLTSKLKQLDILYKYQKQIEIEKELLKAQKEEI
                     REQQKAEKEIQQAKAKLKKEERQFNNEMSKLLKYLNGAQNEIEQQIYADKIKELEDKI
                     KELEKDKEDVLKRESNTRAGYVYIISNIGSFGENVYKIGMTRRLEPMDRVNELSSASV
                     PFPFDVHALIFSEDAPALESTLHNYFRNKEVNKVNPRKEFFKVDLQEIKEVVLKEHNN
                     TVHFTDLAVAEQYYESIKKDVVI"
     gene            complement(2720..3106)
                     /locus_tag="ACF4ZO_001769"
     CDS             complement(2720..3106)
                     /locus_tag="ACF4ZO_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HFD5487277.1"
                     /translation="MVKINEMLSKYNIKLFEFPDTMWERSGFYYPDLRIIYVNQNLSQ
                     IEKEKVILHELGHIEHDPKQYQRLLLKYENQADRFMIRELIKNYLSSHDVVDFNWLQF
                     ATTYQISTTWGQKMIQDEFYKIVSGS"
     gene            complement(3090..3431)
                     /locus_tag="ACF4ZO_001770"
     CDS             complement(3090..3431)
                     /locus_tag="ACF4ZO_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD5487278.1"
                     /translation="MDEKDLKRIIESRYNSVRAFAIENDIPYTTMRSILERGVMNAKA
                     ETIFKICDILGINPESFAEEKTDWQATIDLSNLREKVVMFDGKPLSDKDVEKIEAIIK
                     ISLGVGNGEDK"
     gene            3629..3841
                     /locus_tag="ACF4ZO_001771"
     CDS             3629..3841
                     /locus_tag="ACF4ZO_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HFD5487279.1"
                     /translation="MKNIEHIRKEKGVSLVDIADCLRLKSQIVREKINGDSDFKFGEA
                     LKVQQTFFPEFDIVYLFKERKESSVG"
     gene            3869..4588
                     /locus_tag="ACF4ZO_001772"
     CDS             3869..4588
                     /locus_tag="ACF4ZO_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor KilAC domain-containing
                     protein"
                     /protein_id="HFD5487280.1"
                     /translation="MNHLINVTLNENQEPVVSARDLHKELKVKTRFSEWVKQNFKILE
                     EGYDFTSVVGTTVVNNGAVREIQDYALSLDAAKNLAMVSKTDKGKEVRKYFIQVEKDF
                     NSPEKIMARALLMADKKVHKLEAQIEADRPKVLFADAVEASETSILIGDFAKILRQNG
                     YNIGQNRLFAWLRENGFLIRKNGESYNMPTQRSMDMKLFEVKERTHQEPNGSIRISKT
                     TKMTGRGQQYFINKFLNEKVG"
     gene            4592..4759
                     /locus_tag="ACF4ZO_001773"
     CDS             4592..4759
                     /locus_tag="ACF4ZO_001773"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5487281.1"
                     /translation="MRPKRYPYSGKKNRKAKDISLRLMSKEELSDFSRQIAEATRDNV
                     EPFREPQSMMS"
     gene            4998..5249
                     /locus_tag="ACF4ZO_001774"
     CDS             4998..5249
                     /locus_tag="ACF4ZO_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFD5487282.1"
                     /translation="MDNILMSLSDWIKEFIEKTVNRLVQMKLDELNAELWTREKVAER
                     LNMSPSTFDKYYRRDKNFPKELPAVRWKKAEIIAWLNNK"
     gene            5280..5414
                     /locus_tag="ACF4ZO_001775"
     CDS             5280..5414
                     /locus_tag="ACF4ZO_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5487283.1"
                     /translation="MKLLDFIFTKPKKQKKSKWTIENNGWEANARRYNQKHGLPAKQI
                     "
     gene            5430..5744
                     /locus_tag="ACF4ZO_001776"
     CDS             5430..5744
                     /locus_tag="ACF4ZO_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFD5487284.1"
                     /translation="MNRIKELRKKKGLTQQDLAEEIYVHYRTIQRWENEHKIALDQAQ
                     LLADYFDVSVAYLLGYSDTTKDNKDFITISVKEYNELKNRSDALDGIIETLKDKKCES
                     YF"
     gene            5758..6678
                     /locus_tag="ACF4ZO_001777"
     CDS             5758..6678
                     /locus_tag="ACF4ZO_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017643648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HFD5487285.1"
                     /translation="MADNKKYYYLKLKENFFESDEAIILESMPDGYIYSNILLKLYLR
                     SLKNDGLLMFNNLIPYNAQMLATITRHQIGTVEKAIQIFRDLQLIEILDNGAIYMTNI
                     QNFVGKSSTDADRKRIEYAKTKQLEQISMKCAEKSPPEIEIELDKERELDKEKELDKE
                     KEYNVEQSTTEYNFPSWLESEYVEQVKKGNPKNFDYRIPIAYLNQKTNSNYKFVDSNT
                     NLVKSRLKDKYTLDDFKIVIDKKTAEWGKDADWSKYLRPSTLFNASKFESYLNQPEVA
                     KSDYYQKQQGQRFSQAELDELKKPDPKYGF"
     gene            6688..7530
                     /locus_tag="ACF4ZO_001778"
     CDS             6688..7530
                     /locus_tag="ACF4ZO_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFD5487286.1"
                     /translation="MAFGLMTRESMLASGVIRDTGKTCEKHEMPIYARKMPNHGNRET
                     EFCWQCTTEYIQTKSNAVDIAYNNQSLLAKGYNVFYKESVLSKEIASATLKNYKEHSA
                     IDTQALNYAKRITRDYVKGMEGNSLLQGPPGVGKSHLSMSIAKNINEMFKSYNQSKSV
                     IFVSVPLLSALVKDTFDYDDKKNSKYSQERMSKLLINCDYLILDDLGKESTTGNTIKS
                     ASGWAYTFLFNILDNRTNTIINTNFSRAELMKIYDAAFVDRIIKGAKNNIFKYPDNAE
                     SKRF"
     gene            7530..7667
                     /locus_tag="ACF4ZO_001779"
     CDS             7530..7667
                     /locus_tag="ACF4ZO_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5487287.1"
                     /translation="MELTLTTFFGLSEEHAAKIMALDEDVRTKKIEELRAWRECSKIT
                     F"
     gene            7678..>7982
                     /locus_tag="ACF4ZO_001780"
     CDS             7678..>7982
                     /locus_tag="ACF4ZO_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HFD5487288.1"
                     /translation="MGLLNHLTDLEKRVFCFIPIGAERKVSNQDIQKAIGISDRDVRQ
                     TIYDLVQKGIPVVASKKKHGGYFIATTEEERQEGLRANKSQVNSEVKRIKAVEGVDL"
BASE COUNT         2639 a         1333 c         1443 g         2567 t
ORIGIN      
        1 gtgtattggc tagtcatgta attatttgaa tgacctaaag ccgctgccat atgctcgatt
       61 gggacaccgg ctatttggcc ctgtgtagca aaaaagtgcc tcatcatgtg cggagtaaaa
      121 tgaacgtcgc aatttttatt aattttttta aataagcagt agatgtaatg gctaccgatt
      181 ggttttccta caaaagatgg ctttactttt tcgtcgtctc ctaaaaatag gaaatcagcc
      241 ttatttaaga tgcgatcgtt gcacacggct attttgatag aagtatcaat agcttttttt
      301 agcagttgtg atgtctcaaa atctaaatac acatatcgtt ccgaataagc tgtctttagg
      361 cctccgccat cttttctacc tcttgtcctt gattcgtcta tctttacgac cgcacaatct
      421 ttatcattaa aagttatatt ccctaatttt atgccagcta cctcgcttct acgcaatcca
      481 agatatgtta tcctaaccat tgcgtagtca taatcatcaa gcatttttct ggcaacttta
      541 tcccaagctt taaattcttg cattgatcta cgtttgttga taggttttat ttcgctatcg
      601 ccaatgtcaa taaatttgat gatattatcg tctagcattt tatttttgac agcatgattt
      661 aacataatac taaaaacatc atatatgtgc tttactgtac ttcttgagtt ggtattgagc
      721 agattgttaa tgtagttttc gtattctata cggtttatag cattcatttt tttattgcca
      781 aactttgggc tgatgtgatt tttaaagata ttagtgcgct caacgtatgt gtcaggagac
      841 cacactccag cttttaatct attatcaacg tatatatccc agtattcatc aacagtcaaa
      901 tttttattat aagcaaattc attgttttct atttttcgct caatttcagc tagcaacaaa
      961 cgagcttctt gtatcgtttt tatgccactt tcagtggcct cctttttttc tccgttcaag
     1021 taatagcctc tacggatata gtatcgctta cctttcaaag taatgtacca aaatatgttt
     1081 gggtattttg ttttattgta tttcattctt aaatcctttc ttttttgact tttggacgag
     1141 atcagttgaa aggatattgg catcacctcc taaaaatggt ataattaggt acaataaaac
     1201 gaccttttta atggttgttt tatgtttttg gatagccctc acgcttagac cgccaagttt
     1261 gaaagcgtgg ggctttttta ttcttaaatg actacatctt ttttaattga ctcatagtat
     1321 tgttctgcaa cagctaaatc tgtaaaatgt acagtattat tatgttcttt aagaacaact
     1381 tccttaattt cttgaagatc taccttaaag aattctttcc gtggattaac tttattaact
     1441 tctttattcc ggaagtagtt gtggagtgtg ctttcgagtg ctggtgcatc ttcactaaaa
     1501 attaaagcat gaacgtcaaa tggaaaagga acagaagcgc tgctaagttc gttgactcta
     1561 tccatcggct ctaaccgtct agtcatgccg attttatata cattttcccc aaacgatcca
     1621 atattagaga tgatataaac ataacctgct cgggtgttag attcacgctt aagcacatcc
     1681 tctttatctt tttcaagctc cttgatttta tcttcaagct ctttaatttt atctgcatag
     1741 atttgttgtt caatttcgtt ttgagcgcca tttagatatt tgagcagttt agacatttcg
     1801 ttattgaatt gtctttcttc tttcttgagt ttagctttgg cttgttggat ctctttttcg
     1861 gctttttgct gctctctaat ttcttctttt tgtgctttta gcaattcttt ttcaatttca
     1921 atctgctttt ggtatttgta taatatgtca agttgtttta attttgatgt aagtaattct
     1981 ttgctgattt ttacaccatc aatttcaaat agcttgttta gtgtttcaaa tgttttagcg
     2041 agtttatttc tgtatgtatc tacatttttt atcgttatat ttgataaata ataatcagat
     2101 tctgcattaa aagcacgtag cagttgttta gactgtttgg ctatattgac tttcgttgtg
     2161 gctccgagac tatttacggc aatgccaagc tttattaatt ccttttcgtt taactgcaca
     2221 atagaaagtt catttttgat ttcgttagaa gtgacattgt ctgtaaaatc aacagttgtc
     2281 tgagatagca aagatttgtc gctgttttcc tctataaaaa actctatttc ttttttttga
     2341 gaacttagcg actttatatc attttctagg ttttgtttct ttgcttctcc gctcgatact
     2401 aatgtattga atttttttac agcctcctct tcagttttta tagctatctt actagcttcg
     2461 ttttttattt ctgctgctct ctcgtatgca tcgtttttga tagcagaggc ttcaatttcg
     2521 ctctctttta tctcattcca ttttttctgt tgtgaaggtg ttagattggg atacgttttt
     2581 tgcctttgta aaaataaccc cagtccaaac aagattgaaa taccatacgt gaaggggtac
     2641 aataaaatta taattagaat aaaccaaaac ctaaaataaa acggcaatcc atctgatttc
     2701 ttcattttca aatcctttct taactacctg atacgatctt ataaaattcg tcttgtatca
     2761 tcttttgccc ccacgttgtc gatatttgat atgtcgtagc aaactgtaac caattaaaat
     2821 caacgacatc gtgggatgac aagtaattct tgatcaattc cctaatcata aatctatcgg
     2881 cttgattttc atattttagt agcaatcttt gatattgctt aggatcgtgt tcgatatggc
     2941 ccagctcatg taaaataact ttttcttttt ctatttgtga tagattttga ttgacataaa
     3001 ttatcctaag gtcaggatag taaaaccctg acctttccca cattgtgtcg ggaaactcga
     3061 ataactttat gttgtactta ctaagcatct catttatctt caccattccc tactcctaaa
     3121 gatattttaa taatagcttc aattttctct acgtctttgt cagacaaagg tttgccgtcg
     3181 aacatcacaa ccttttcgcg tagattagat aggtcaatag tggcctgcca atcagttttt
     3241 tcttcagcaa aactttctgg gttaattcca agaatatcac atattttaaa aatagtttct
     3301 gcttttgcat tcatcacacc gcgctctaaa atggagcgca ttgttgtgta tgggatatca
     3361 ttttcaatag caaaagccct aacgctatta tatctacttt cgataatcct ctttaaatct
     3421 ttttcatcca tttttttaat ttcctttttt ctttttctac tatataataa catacgaaaa
     3481 atcatatttc aagacaaaaa aataacaaaa aatttaaaaa aactgttgac tatatacgaa
     3541 aaatcatata taattaaatc aagcttaagg aaacgacagc tttttaaaat aaaataatat
     3601 acgaaaaatc gtatcggaaa ggaatgatat gaaaaacatt gaacacattc gaaaagaaaa
     3661 aggtgtttca ttggttgata ttgccgactg tttacggttg aaatctcaaa tagttcgaga
     3721 aaaaattaac ggtgactctg attttaaatt tggtgaagca ttgaaagttc aacaaacttt
     3781 ttttccagaa tttgatatcg tctatctttt taaagagcgt aaagaatcat ctgtaggatg
     3841 atatacgaaa attcgtagaa aggaaattat gaatcatcta attaacgtaa cactaaacga
     3901 aaatcaagaa ccagtagtaa gtgcaagaga cttacataaa gaattaaaag tcaaaactcg
     3961 ttttagtgag tgggtaaaac aaaactttaa aattcttgaa gaaggatatg attttacaag
     4021 tgtagttgga actacggttg taaataatgg ggctgtcaga gaaatccaag actacgctct
     4081 ctcacttgat gctgccaaaa atttggcaat ggtatccaag actgacaaag gcaaagaagt
     4141 ccgtaaatac ttcatccagg ttgaaaaaga tttcaacagt cccgagaaaa ttatggcaag
     4201 ggcgttgctg atggcggaca agaaagtgca taaattagag gctcagattg aggcagaccg
     4261 tccaaaggtg ctatttgctg atgcggttga ggctagtgag acatctatct tgattggtga
     4321 ttttgctaaa atcttacgtc agaatggtta taacatcggt caaaatcgct tattcgcttg
     4381 gttgcgtgag aatggcttcc tgattcgtaa aaatggcgag agctacaaca tgccgacaca
     4441 acgaagcatg gacatgaagc tgttcgaagt caaggaacgg acgcaccagg agccaaatgg
     4501 cagtatccgt atcagcaaaa ctaccaagat gacaggtaga ggccagcagt attttattaa
     4561 taaattttta aatgagaaag tggggtagag catgagacca aaacgatacc catatagcgg
     4621 gaagaaaaac agaaaagcaa aagacatcag cttgagactg atgtctaaag aggaattatc
     4681 tgattttagt cgtcagattg ctgaagccac tcgtgataat gtcgaaccat ttcgagagcc
     4741 gcaaagtatg atgagctaag tattaacttt gcaaggttta cagattcccc ttcgctttct
     4801 ttcgcatatc tattgtaatg gtactcaata acttccagaa tttcttcggt tttaccattg
     4861 cttagagatt gggcgaaatt gttgaaatct ttagccatat aatcacctcc cttcgagatg
     4921 attataacaa aaaagtccga cggcgatcgg actcaaaaca aacttaattt acttcattat
     4981 accacaagga ggcaactatg gacaatatct taatgagttt gtccgactgg ataaaagaat
     5041 ttattgaaaa aacagttaac agattagtcc aaatgaagtt agacgaactc aatgcagagt
     5101 tatggactag agaaaaagta gcggagaggc ttaacatgag ccccagcact tttgacaaat
     5161 actacagacg cgacaaaaat tttccaaagg aattgccagc tgtccgttgg aaaaaagctg
     5221 aaatcatagc ttggctaaat aacaaataag acttttggac gagatcgagg agaaataaca
     5281 tgaaactatt agattttatt tttacaaaac caaaaaaaca gaaaaaatca aaatggacga
     5341 ttgaaaataa cggctgggaa gctaatgcac gtagatataa ccaaaagcac ggtttacctg
     5401 ctaaacaaat ttagtaggag acgcataaca tgaatagaat aaaagagtta cgcaaaaaaa
     5461 aaggcttgac tcagcaagat cttgcagaag aaatatacgt gcattacagg acgatccaac
     5521 gctgggaaaa tgaacacaaa atagcgcttg atcaagcgca attactagca gattattttg
     5581 atgtatcagt tgcttactta ctcggatata gcgatactac aaaagataac aaagatttta
     5641 tcacaatatc tgtcaaagag tacaatgagc ttaaaaaccg atcagatgct ttagatggaa
     5701 ttattgagac gttaaaagat aagaaatgtg aaagctattt ttgaagaagg gagataaatg
     5761 gcagataaca aaaagtatta ctacttaaaa ttaaaggaaa atttctttga aagtgatgaa
     5821 gcaatcattt tagaaagtat gcctgacggc tatatctata gcaatatttt gctcaagtta
     5881 tatctaagaa gtttaaaaaa tgatggctta ttaatgttta acaatcttat tccttacaac
     5941 gcacaaatgc ttgccacaat tacaaggcat cagattggca ctgtcgaaaa ggccattcaa
     6001 atttttagag acctacaatt aattgaaatt cttgataatg gtgcgatata tatgacaaat
     6061 attcaaaatt ttgttggtaa atcaagcaca gatgctgaca gaaaaagaat tgaatatgca
     6121 aagactaaac aacttgaaca aatctccatg aaatgtgcgg agaaatctcc accagagata
     6181 gagatagagt tagataaaga gagagagtta gataaagaga aagagttaga taaagagaaa
     6241 gaatataatg tcgagcaaag cacgactgaa tataatttcc caagttggct tgaatctgaa
     6301 tatgtcgaac aagtcaaaaa aggtaatcct aagaattttg attacagaat tccgatagca
     6361 tatctaaatc aaaagacgaa ttctaactat aagtttgttg atagtaacac taatcttgtt
     6421 aagtcgaggt taaaagataa gtacacgcta gatgatttta aaattgtaat agacaaaaaa
     6481 actgctgaat ggggtaaaga tgctgattgg agcaagtatc ttaggccatc aacgttattt
     6541 aacgctagca agtttgagag ttatcttaat cagccagaag ttgctaaaag tgattattac
     6601 cagaagcagc aaggacaacg attttcgcaa gctgagttag acgagcttaa aaaaccagat
     6661 ccgaaatatg ggttttagga ggtatctatg gcttttggtt taatgacgag agaaagcatg
     6721 cttgctagtg gcgttattag agatactgga aaaacatgcg aaaagcacga gatgccaatt
     6781 tatgctagga aaatgccaaa tcatggcaat agagaaacag aattttgttg gcaatgtaca
     6841 acagagtata tccaaacgaa aagtaatgcg gttgacattg cgtacaacaa ccagtcgttg
     6901 ctagctaagg gttataacgt gttttataaa gagagcgttt tatcaaagga aattgctagt
     6961 gctacgttga aaaactacaa ggaacatagt gctatagata cacaagcgct aaactatgcc
     7021 aaacgaatca ccagagatta tgttaaagga atggaaggta actccctctt acaaggacct
     7081 ccaggagttg gcaagagcca cttgtctatg agtattgcta aaaatattaa cgagatgttt
     7141 aaatcttaca atcaatcaaa gagtgtgata tttgtttcag tacctttgtt gtccgcatta
     7201 gtcaaagata catttgatta tgacgataaa aaaaatagca aatattcgca agaaagaatg
     7261 tcaaagcttc tcatcaattg tgattatctg atacttgatg acttaggcaa ggagtcaacc
     7321 acaggtaaca ccattaaatc tgctagcggt tgggcatata cgtttttatt taatattttg
     7381 gataatcgga caaatactat cattaataca aattttagta gagctgagct tatgaaaatt
     7441 tacgatgctg cttttgtcga tcgcataatc aaaggtgcaa aaaacaatat ttttaaatat
     7501 ccagataatg cagaaagtaa gaggttctga tggaattgac actaacaaca tttttcgggc
     7561 tatctgagga acatgcggca aaaatcatgg cgctagatga agatgttcga acaaagaaaa
     7621 ttgaagaatt aagagcatgg agagagtgct caaaaatcac gttttgaagg gggaattatg
     7681 ggattactaa atcatttaac agacttagaa aagcgagtgt tttgctttat ccccattggg
     7741 gcagagcgaa aagtgtctaa tcaagacatc cagaaagcta ttgggatatc cgacagagat
     7801 gtcagacaga caatctatga tttagtccaa aagggtatac ccgttgtcgc tagcaaaaag
     7861 aagcacggcg gatattttat cgccaccaca gaagaggagc gtcaagaagg gcttagagct
     7921 aataaaagtc aagttaattc agaagtgaaa cgaattaaag cagttgaagg tgttgatcta
     7981 ga
//
LOCUS       DAXMQE010000058         7491 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.058, whole genome shotgun sequence.
ACCESSION   DAXMQE010000058 DAXMQE010000000
VERSION     DAXMQE010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7491)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7491)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7491
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.058"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            complement(<1..241)
                     /locus_tag="ACF4ZO_001781"
     CDS             complement(<1..241)
                     /locus_tag="ACF4ZO_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_115223326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronoglucosaminidase"
                     /protein_id="HFD5487289.1"
                     /translation="MTENIPLRVQFKRMSADEWARSDVILLEGEIGFETDTGYAKFGN
                     GKSKFSALKYLTGPKGPKGDTGFQGKTGGTGPRGPA"
     gene            complement(241..2214)
                     /locus_tag="ACF4ZO_001782"
     CDS             complement(241..2214)
                     /locus_tag="ACF4ZO_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail spike protein"
                     /protein_id="HFD5487290.1"
                     /translation="MEVQGLISIKDDNTPLVAAFEDEITQEANSDYKLSFKYPAKHEY
                     RPLIKKGIILEADDLHGTQLFRVFEITKRHGYINVYGNQVADDLNGYAIDSISVDRVQ
                     GMTVMSELAGNIKREHPFSFFSDIDGRHTFNQSDVSVMDALANGKHSIMGQWGGELVR
                     DKYQVNLLKKAGKDTETLFMYKKNLKSYEETDTIKGLISILHLVAEVEEQREEESREV
                     SDADIGHNEVSKKKTIRVTVESKLKDTHPIIVEKTIKVQDQDVKTEEDLLAYGKKYFE
                     KTLCDIPGNSLKIDVTNNYEGAVRLFDTAIVFHELYDRDLRMQITGYRFAPMANRLKS
                     IIFGEIKTNLAKQISNQIDNKVAESTAQHDAAFEAKLQKQIDNANRIFDTKEAKLREE
                     IEDGIKKAEANAEVKVAEVNAKVLEAEELAKAVDERLKKFLSDADTKEQDFDKKLEEF
                     RTSLKDLEVDEKQIDDALAKAGFSKDSLADIKAKLEDTSETATVTANIVGSTGGTFYN
                     RNRLDGDTDKVITFEQGYIDIAHNGEGFEEGKTYTISFEATCELLRKVGITVTQANMK
                     GARLVLTPKNPKLVVESFGLTKDTETINVYPFSYTVLVTSDWYKSKQIDLNASEVQEL
                     ALEMAYKDVVDGNNATIAGQWSDSPQMILDGGS"
     gene            complement(2196..2891)
                     /locus_tag="ACF4ZO_001783"
     CDS             complement(2196..2891)
                     /locus_tag="ACF4ZO_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5487291.1"
                     /translation="MIPKVIIDGFDTSTIPNCVLTGYDVGDVLSPHFVENEVYGMNGT
                     SRGLESYNESKPTLTWHLSTFDDAVNLVNHLDGLGKIIEFWHIPKSFYYYDCLSVKIN
                     AVTMNSWRVTLKLALYPFRYAKGISDVTIAGNGSINNPGNVFSEPKIIVEGTGKGTLT
                     IDKQVMELNLSGKATIECKHGQQCVYDGEGNVKNSIRIRGRFFEIQPGTQGIAVSGGI
                     ARLTISPRWRYKV"
     gene            complement(2888..5251)
                     /locus_tag="ACF4ZO_001784"
     CDS             complement(2888..5251)
                     /locus_tag="ACF4ZO_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5487292.1"
                     /translation="MATELGQAYVQIMPSARGISGAISKQLDPEARSAGLSAGKLFGS
                     KLKLAALAATAGLGILLKKTISASLSTGADLQQSFGGIDTLYKGAETAVKGFAKEAYK
                     AGISANTYAEQAVSMGASLKQSLGGDAVAAAKAANMAIMDMADNSAKMGTDITSIQMA
                     YQGFAKQNYTMLDNLRLGYGGTKEEMKRLLSDAEKLPAAMGKKFDLSNYADVVEAIHL
                     VQDNMGIAGVAAEEAKTTFSGSLAAMKSSFTNVLAGLSLGDDIRPALRGLAETTSNFL
                     FGNFIPMVANIFKGLPSAIGTFIGAATPIIASQFKGLMSSLGISIDLSPITAKFAQIG
                     QNLQPVFNGLKTAFSQLPSFFTSIGSAVAPVIDTIISGLARLDFSGFEALISAILPAI
                     QTGFQTFMSIVGPAISQLVNSFVNLWNACQPLVTILNGALMPAFQILGAFLGGVLQGI
                     LGSISFAFDALKVVIEFLTPIIDWLVQGFNAISPALQIVAQWVGNVIGIFTSLGASGQ
                     GLSSMLSSAWGNIQTVVSTAKNMITLAIDGIKLVFSNLGNAGNILKGLLSAAWSAMQN
                     AVVIAKGIINSAISAIKTAFSSFGNLVSSVSGTIKSVIGSLKNAFYSLASIDLVGAGR
                     AIMQGFLNGLKSMWGAITGFVGGIADWIRKHKGPISYDRVLLKPAGKVIMQGFNNSLM
                     DGFKEVKSNVSGMADDLAGTITGKSLSLGIDAKPSVTADDLLSSNISTKTTVGSATSD
                     LSLFFVKVLALLQDILDKNTDVYLDKEKVSAILYEEFAKIMAREGIA"
     gene            complement(5251..5622)
                     /locus_tag="ACF4ZO_001785"
     CDS             complement(5251..5622)
                     /locus_tag="ACF4ZO_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5361 domain-containing protein"
                     /protein_id="HFD5487293.1"
                     /translation="MIAKDDDALTCDLAETYGIYDYRQLPAYQVAVFAVGLRSNSRIK
                     MALSGETEALDTVLLAGIYDNTNLLFWSKTKDGQSGQNKPKSVVEAISGSKSQKANDV
                     ISFASGEDFENARKQLLGGDG"
     gene            complement(5637..5900)
                     /locus_tag="ACF4ZO_001786"
     CDS             complement(5637..5900)
                     /locus_tag="ACF4ZO_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5487294.1"
                     /translation="MEILKGKTTSGFEYEIPKKRLKNFELVEAIAEEETDPTAVVKIV
                     NLLLGDAAKSLKEHVRDAEGIVDVEAIGVEIKEIFESQKDLKN"
     gene            complement(5911..6501)
                     /locus_tag="ACF4ZO_001787"
     CDS             complement(5911..6501)
                     /locus_tag="ACF4ZO_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFD5487295.1"
                     /translation="MANDTKNVTSAKPKAGGAIYSAPLGTTLPEDAKSKLDTKFKNLG
                     YVSEDGVVNEDTRSSENIKAWGGDIVGSVQTEKEDKFTYKLIESLNVEVLKEVYGAAN
                     VTGDLDKGIHIKSNSKELEAHAIVIDMIMNGGILKRIVLPNAKVDEVGEIKYVDGEVV
                     GYETTLKCFPDEKGDTHHEYIVKPGEANKKENSFEM"
     gene            complement(6517..6852)
                     /locus_tag="ACF4ZO_001788"
     CDS             complement(6517..6852)
                     /locus_tag="ACF4ZO_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5487296.1"
                     /translation="MIEVIIKKYLDEHLDVPSFFEHQKDEPARFIILEKTSGAKQNHL
                     LSSTFAFQSYAESLYEAALLNDKVKQVIEQLDVLPQVSGVHLNADYNFTDTATKRYRY
                     QAVFDINHY"
     gene            complement(6853..7089)
                     /locus_tag="ACF4ZO_001789"
     CDS             complement(6853..7089)
                     /locus_tag="ACF4ZO_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5487297.1"
                     /translation="MSKFKFKLNKAGVAELMKSSEMQQVLTTKATAIRERCGDGYAQD
                     IHVGKNRANAMVSAKTIKAKKDNSKNNTLLKAVR"
     gene            complement(7082..7420)
                     /locus_tag="ACF4ZO_001790"
     CDS             complement(7082..7420)
                     /locus_tag="ACF4ZO_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5487298.1"
                     /translation="MGKLRGITITLIDKVTIDIDPFGNPIKKDKEISVDNVLVSPATS
                     DDITSQLSLSGKKAVYTLAIPKGDNHDWGDKEVRFFGEKWRTVGLALEGIEELIPLEW
                     NKKVMVERYE"
     gene            complement(7380..>7491)
                     /locus_tag="ACF4ZO_001791"
     CDS             complement(7380..>7491)
                     /locus_tag="ACF4ZO_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="Gp19/Gp15/Gp42 family protein"
                     /protein_id="HFD5487299.1"
                     /translation="LFIKDNELKRLGLKKQRYGGIELYGEIKRDNDYFDR"
BASE COUNT         2113 a         1703 c         1224 g         2451 t
ORIGIN      
        1 cagcagggcc ccgaggacca gttcctccag ttttaccttg gaaaccagtg tctcctttag
       61 gaccttttgg tccggtaagg tatttgagtg cgctaaactt gcttttccca ttaccaaatt
      121 tagcatagcc tgtatcagtc tcaaaaccta tctcaccctc aagcaagatg acatcactac
      181 gagcccactc atcagcgctc atgcgcttaa attggactct taatggtata ttttcagtca
      241 ttaactacct ccatctaaaa tcatttgcgg gctgtctgac cactgccctg ctatcgtggc
      301 attattaccg tcaaccacat ctttataagc catctcaagg gccaattcct gcacctccga
      361 cgcgtttaaa tctatttgct tagatttata ccagtcgctg gttacaagca ctgtgtagct
      421 aaacggatag acattgatag tctcagtatc cttagtcaag ccaaaactct cgacaactaa
      481 tttgggattt ttaggtgtta acactaagcg agcacctttc atgttagcct gtgtcactgt
      541 gattcctact ttacgcagta gctcgcaggt tgcctcaaag ctgatagtgt atgtcttgcc
      601 ttcttcaaaa ccttcaccat tatgggcaat gtcaatataa ccttgttcaa aagtgataac
      661 tttgtcagta tcaccatcca gtctgttgcg attgtaaaac gtgccgccag ttgatccaac
      721 aatgttagct gtaactgtgg cagtttcaga cgtgtcttcc agtttagctt taatgtcagc
      781 taagctatcc ttgctaaaac cggctttggc caaagcatca tcaatctgct tttcatcaac
      841 ttcaaggtct ttaagagacg ttctaaattc ttcaagtttt ttatcaaaat cttgctcttt
      901 agtgtcagca tcagataaaa attttttgag tcgctcatcg actgccttgg ctagctcctc
      961 agcttccagc actttagcgt taacctcagc aactttgacc tctgcattag cttcagcttt
     1021 tttgatgcca tcttcaatct cttcacggag tttagcttct tttgtgtcaa aaatacgatt
     1081 agcattatca atctgctttt gtaattttgc ttcaaatgct gcgtcatgtt gagcagttga
     1141 ttcagctacc ttattgtcaa tttgattgct aatttgtttt gctaagttgg tcttaatctc
     1201 tccaaagatg atggatttta accgattggc cataggggcg aaccgatagc cagtgatttg
     1261 cattcgtaag tctctgtcat agagctcgtg gaagacaatt gctgtgtcaa atagcctaac
     1321 agcgccctcg tagttattag taacatcaat ttttaaacta ttacctggta tgtcgcaaag
     1381 agttttttca aagtatttct taccatatgc aagcaagtcc tcttctgttt tgacatcttg
     1441 atcctgcacc ttgatagtct tttcaacaat tatcggatga gtgtctttga gcttgctctc
     1501 aacagttacc ctaatcgttt tctttttgct aacttcattg tggccaatgt ctgcatcaga
     1561 aacttctcta gattcctctt cccgctgctc ctcaacttct gcaacgagat gcagtatcga
     1621 gatgagacct tttatagtat ctgtctcctc ataagatttg aggtttttct tatacataaa
     1681 taaggtctca gtgtctttac cagctttttt gagcaaatta acctgatact tatcacgtac
     1741 aagctcgcca ccccactgcc ccatgattga gtgcttgcca ttagctaaag cgtccataac
     1801 agatacgtct gattgattaa atgtgtgacg accgtcaata tcactaaaaa agctaaaagg
     1861 atgctcacgc ttgatattac ctgctaactc tgacattact gtcatacctt gcaccctatc
     1921 aacactgata gagtcaattg catagccatt taaatcatcg gcgacctgat taccataaac
     1981 attgatatag ccatgtcgct tagtaatctc aaaaacccta aaaagctgag ttccatgtag
     2041 gtcatcagct tctaggatta ttcctttttt gatcaagggg cgatactcat gtttagctgg
     2101 atacttaaaa cttaatttat aatcgctatt cgcttcctgt gtaatctcat cttcaaaggc
     2161 tgctacaaga ggtgtattat catctttaat cgatatcaaa ccttgtacct ccaccttgga
     2221 ctaattgtta acctggcaat gcctccgctt acggcaatac cttgtgtgcc aggttgtatt
     2281 tcaaaaaatc ttcctcttat tcggattgag tttttcacat taccttcacc atcataaacg
     2341 cattgttggc catgtttgca ctcaatcgtt gctttacctg acaaatttaa ttccatgacc
     2401 tgtttgtcaa tggttagtgt tcctttgccg gtaccctcaa caattatctt aggttcacta
     2461 aaaacatttc ctggattatt tatacttcca ttgcctgcaa tcgttacatc tgagatacct
     2521 ttcgcatacc taaatggata tagtgcaagt ttaagtgtga ctctccacga gttcatagtt
     2581 accgcattga ttttgacaga taggcaatca taataataaa atgacttcgg aatatgccaa
     2641 aattcaatga ttttcccaag tccgtctaaa tgattcacta aattaactgc atcatcaaaa
     2701 gtgctcaaat gccatgttag agtgggtttc gactcattgt atgactctaa tcccctacta
     2761 gtaccattca tcccatacac ttcattttcg acaaaatgag gggataaaac atcccctaca
     2821 tcataaccag ttaggacaca attagggatt gtagaggtat caaaaccatc aataataacc
     2881 tttggtatca tgcaatcccc tctctagcca tgattttggc aaattcttcg tataaaatag
     2941 cgctgacttt ttctttgtct agatagacat ccgtattttt atcaaggata tcttgcaaca
     3001 gagcaagcac cttaacaaaa aataatgaca agtcacttgt agcagaaccg actgtagttt
     3061 tagtactaat attgcttgat agtaagtcat cagctgtgac gcttggttta gcatcgatac
     3121 cgagagatag acttttacct gttatggtgc ctgcaagatc gtcagccatg ccagatacat
     3181 ttgatttaac ctctttaaag ccatccatca agctattgtt gaacccttgc atgattactt
     3241 tacctgcggg ttttagcaaa accctatcgt atgagatagg ccctttgtgc ttacggatcc
     3301 agtcagcaat acccccaaca aagccggtga ttgcccccca catcgatttt agtccattta
     3361 gaaatccttg catgattgca cgtcctgcac caactaagtc aatacttgct aaactgtaaa
     3421 acgcattttt taaactgcca ataacagatt ttatagttcc acttacgcta gatacaagat
     3481 taccaaagct gctaaatgct gtttttatag cgcttatcgc actgttgata atacctttag
     3541 ctatcactac tgcattttgc atagctgacc acgctgccga aagtaatcct tttaaaatat
     3601 ttccagcatt ccctagattg ctaaatacca atttaatacc atcaatcgcc aaagttatca
     3661 tatttttagc tgtcgaaact actgtttgga tgttccccca agcactgctt agcatactac
     3721 ttaaaccttg cccagatgca cctaagctag taaatatacc aatgacatta ccaacccact
     3781 gggcaacgat ttgtaatgcc ggtgaaatag cattaaaacc ttgtacaagc caatcaataa
     3841 ttggcgttaa aaactcaata acaactttta aagcatcaaa tgcaaagcta atactgccaa
     3901 ggattccttg taagactccg ccgagaaaag ctcctaaaat ttgaaaagct ggcatcaatg
     3961 cgccatttaa tattgttact agaggttggc aagcattcca aagattaaca aaactattta
     4021 caagctgact aatcgctgga cctacaatag acatgaacgt ttggaaccct gtttgaattg
     4081 ctggtaagat tgctgaaatt aaagcctcaa aaccactgaa atctaatctg gctaatccgc
     4141 taataatagt gtctattact ggtgcaactg cactaccaat gctagtaaaa aatgatggca
     4201 actgactaaa agccgttttt aaaccgttaa aaacaggttg taaattttgg ccaatctgtg
     4261 caaatttagc agtaatagga cttaaatcaa tactaatccc aaggctactc attagccctt
     4321 taaattgact ggcaataata ggagttgctg ctccaataaa agtaccaatt gccgatggta
     4381 atcctttaaa gatatttgcc accatcggaa taaagttacc aaataagaaa ttagaagttg
     4441 tttcagccag tcctcgtaaa gcaggtctta tatcatctcc tagtgataaa cctgccagta
     4501 catttgtaaa agaggacttc atagcagcta gtgagcctga aaatgtagtt tttgcttctt
     4561 cagcagcaac tccagcgata cccatgttat cctgtaccaa gtgtatagcc tcaaccacat
     4621 cagcataatt actcaaatca aacttcttgc ccatagcggc aggtaacttt tcagcgtctg
     4681 ataaaagacg cttcatctct tcttttgtgc cgccgtatcc aagtcttagg ttatcaagca
     4741 ttgtatagtt ttgcttagca aatccctggt aagccatttg gattgatgtg atatcagtac
     4801 ccatcttagc cgagttgtcg gccatatcca tgattgccat gttagcagcc ttggcagccg
     4861 cgacagcatc acctccaagt gattgcttta gagatgcacc cattgaaact gcttgctctg
     4921 cataagtatt tgctgatata ccagctttgt acgcttcttt agcaaaccct ttgacagcag
     4981 tctcagcgcc cttatacaag gtatcaatac caccaaaaga ttgctgtaag tcagcaccag
     5041 tggacaaaga tgcagaaatt gttttcttga gtaaaatacc taaaccagca gtagccgcta
     5101 gagccgctaa tttcaattta ctaccaaaca atttacctgc gctcaaacca gccgaccttg
     5161 cttctggatc aagttgcttt gagattgctc cacttattcc acgagcggat ggcataattt
     5221 gcacatacgc ttgaccaagt tctgttgcca ttagccatca cctcctagta attgtttacg
     5281 tgcattttca aaatcctcgc cagacgcaaa agaaatgaca tcattagctt tttgtgattt
     5341 agatccagat atagcttcca ccacggattt aggtttgttt tgaccagatt gaccatcctt
     5401 agttttagac caaaacagca aattagtatt atcgtaaata ccagctaaca aaacagtatc
     5461 caaagcctca gtctctccag ataatgccat ttttatccta gagttagatc tcaaaccgac
     5521 agcaaaaaca gccacctgat aagcaggtag ctgtctgtaa tcatatatgc cgtatgtttc
     5581 agctaaatca caagtcaatg catcatcatc ttttgctatc atctgagcga ggattgctag
     5641 ttttttaaat ctttttgact ttcaaaaatt tctttgattt ctactccgat agcttcaacg
     5701 tctacgatac cttctgcatc tcgtacatgt tcttttagag acttagcagc atcaccaagt
     5761 aacaaattaa cgattttaac cactgctgtt ggatcggttt cctcttctgc aatagcttca
     5821 acaagttcaa agttttttaa tcgtttttta gggatttcgt attcaaatcc tgatgttgtt
     5881 tttcctttta agatttccat ttactcccct ttacatttca aagctgtttt cttttttatt
     5941 agcttctcca ggttttacaa tatactcatg atgagtatct cctttttcat ctggaaaaca
     6001 ttttagtgtt gtttcgtatc cgacaacttc gccgtcaaca tacttaattt cacctacctc
     6061 atcgactttt gcattcggta aaactatgcg cttcagaatt ccaccattca tgatcatatc
     6121 aataacgata gcatgagctt caagttcttt tgaatttgat ttaatatgga ttcccttatc
     6181 taaatctcca gtaacattgg cagcgccata aacttctttt aagacttcta catttagtga
     6241 ttcaatcagc ttataagtaa atttatcctc tttttctgtc tgcacagatc caacaatatc
     6301 tccaccccac gctttaatat tttcagatga gcgtgtatct tcattgacca caccatcctc
     6361 ggatacataa cccaaattct taaatttagt atctaatttt gattttgcat cctcgggcaa
     6421 tgttgtcccc aacggtgcag aataaatagc tccgcctgct tttggctttg cagatgttac
     6481 atttttagta tcatttgcca ttattatctc cttttgttaa tagtgattaa tgtcaaatac
     6541 agcttgatat cgataacgct tagttgctgt atctgtaaaa ttgtagtcag cgttaagatg
     6601 tacaccagaa acttgtggca agacatcaag ctgctcaatt acttgcttta ctttgtcatt
     6661 aagtaaagcc gcctcataca acgattcggc ataactttga aaagcaaacg tggaacttag
     6721 caaatgattt tgcttagccc cgctagtctt ttctaagatg atgaatcgtg caggttcatc
     6781 tttttgatgt tcaaaaaaag acggcacatc taagtgctcg tctaaatatt ttttgataat
     6841 tacttcaatc aatcatcgca ccgccttcaa caatgtgttg ttttttgaat tatctttctt
     6901 ggcctttatg gttttagcac tgaccatagc attagcccta tttttcccga catggatatc
     6961 ttgggcgtaa ccatcaccac aacgttctct gatggctgtg gccttagtgg ttaatacctg
     7021 ctgcatttct gatgatttca tcaattcagc aacaccagct ttattgagct tgaatttaaa
     7081 cttactcata tctttccacc ataactttct tattccattc aagcggaata agctcttcaa
     7141 taccttcaag agctaggccg acagtgcgcc acttttctcc aaagaatcta acttccttat
     7201 ctccccaatc gtggttgtct ccttttggaa tagctaaagt gtaaacagct ttttttcctg
     7261 aaaggctaag ctggcttgtt atgtcatcgc ttgttgctgg cgatacaagg acattatcga
     7321 cagatatttc tttatctttt tttattggat ttccgaaagg gtctatatcg atagttactt
     7381 tatctatcaa agtaatcgtt atccctctta atttccccat aaagctcaat acctccatac
     7441 ctctgctttt ttagaccaag ccgtttaagc tcattgtctt ttataaacag t
//
LOCUS       DAXMQE010000059         7427 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.059, whole genome shotgun sequence.
ACCESSION   DAXMQE010000059 DAXMQE010000000
VERSION     DAXMQE010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7427)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7427)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7427
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.059"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            208..426
                     /locus_tag="ACF4ZO_001792"
     CDS             208..426
                     /locus_tag="ACF4ZO_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5487300.1"
                     /translation="MALLFYYYVRKNQVKKLSQLKNLTEIFRKFIILTINNISVIKAF
                     QTAGVLFGPVKAANARESSIWFENLTKQ"
     gene            682..1092
                     /locus_tag="ACF4ZO_001793"
     CDS             682..1092
                     /locus_tag="ACF4ZO_001793"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HFD5487301.1"
                     /translation="MIREIITDHFLLQQKAQVAKKEDLWIGQDLQDTLAFYRQECLGM
                     AANMIGEQKRIVIVSMGFIDLVMFNPVMVSKKGIYQTKESCLSLSGYRKTQRYDKITV
                     EYLDHNWRPKRLSLTGLTAQICQHELDHLEGILI"
     gene            complement(1173..3185)
                     /locus_tag="ACF4ZO_001794"
     CDS             complement(1173..3185)
                     /locus_tag="ACF4ZO_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HFD5487302.1"
                     /translation="MKKYFILKSSVLSILTSFTLLVTDVQADQVDVQFLGVNDFHGAL
                     DNTGTAYTPSGKIPNAGTAAQLGAYMDDAEIDFKQANQDGTSIRVQAGDMVGASPANS
                     ALLQDEPTVKVFNKMKFEYGTLGNHEFDEGLDEFNRIMTGQAPDPESTINDITKQYEH
                     EASHQTIVIANVIDKKTNDIPYGWKPYAIKDIAINDKIVKIGFIGVVTTEIPNLVLKQ
                     NYEHYQFLDVAETIAKYAKELQEQHVHAIVVLAHIPATSKDGVVDHEMATVMEKVNQI
                     YPEHSIDIIFAGHNHQYTNGTIGKTRIVQALSQGKAYADVRGTLDTDTNDFIKTPSAN
                     VVAVAPGIKTENSDIKAIINHANDIVKTVTERKIGTATNSSTISKTENIDKESPVGNL
                     VTTAQLTIAKKTFPTVDFAMTNNGGIRSDLVVKNDRTITWGAAQAVQPFGNILQVIQM
                     TGQHIYDVLNQQYDENQTYFLQMSGLTYTYTDNDPKNSDTPFKIVKVYKDNGEEINLT
                     TTYTVVVNDFLYGGGDGFSAFKKAKLIGAINTDTEAFITYITNLEASGKTVNATIKGV
                     KNYVTSNLESSTKVNSAGKHSIISKVFRNRDGNIVSSEIISDLLTSTENTNNSLGKKE
                     TTTNKNTISSSTLPITGDNYKMSPIMTILALISLGGLNAFIKKRKS"
     gene            3405..4055
                     /locus_tag="ACF4ZO_001795"
     CDS             3405..4055
                     /locus_tag="ACF4ZO_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015969 - guanosine tetraphosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HFD5487303.1"
                     /translation="MKERLEHYSTSSIYSGFEVYLPLVLQTITDVIIAENIKSKKETG
                     FKLYEHFTSRIKSEASMIEKCQRKQLPLTSKSALKIIKDSIGIRIICGFIDDIYRMVD
                     LLKSIPGMSVNTEKDYILNAKPNGYRSYHLILELETHFPDILGKKKGCYFIEVQLRTI
                     AQDSWASLEHQMKYKHQVANAEMITRELKRCADELASCDVTMQTIRQLIQETTEEE"
     gene            4058..4726
                     /locus_tag="ACF4ZO_001796"
     CDS             4058..4726
                     /locus_tag="ACF4ZO_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFD5487304.1"
                     /translation="MKILLAEDEWQMSNVLTTAMTHQGYDVDVVFNGQEAIDKAKDNA
                     YDIMILDIMMPIKSGIEALKEIRASGNCSHIIMLTAMAEINDRVTGLDAGADDYLTKP
                     FSLKELLARLRSMERRVESFTPQVLQFAGVTLNINEQELSAGNAIRLASKEGKLMAFL
                     MLNQGKYLDTKTLYQHVWSDQEDYDTSIVWVYISYLRQKLLAIQANVIIAGDKDTSYC
                     LLEK"
     gene            4735..5967
                     /locus_tag="ACF4ZO_001797"
     CDS             4735..5967
                     /locus_tag="ACF4ZO_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFD5487305.1"
                     /translation="MFNRIRIRFIMIASIAIFIILSSIVGIINTARCYQSQQEINRIL
                     HLISSNKGKLPDTTESSKRLGTKLSEDSLSQFRYYSVIFNANGHLLSSNTANISALDR
                     EEAQYFARLFAKSGEEKGSYRHQDSVYSYLITQLPNEEKLVVILDTTFYFRSVGDLLA
                     VSMMLAFGGFIFFVVLVSLFSGMVIKPFVQNYEKQRRFITNAGHELKTPLAIISANNE
                     LVELMTGESEWTKSTSDQVKRLTGLINQMITLARLEERPDVVLHMVDFSAIAQDAAED
                     FKSLVLKDGKRFDLTIQPNIMIKAEEKSLFELVTILVDNANKYCDPKGLVKVSLTTIG
                     RRRKRAKLEVSNTYLEGKSIDYSRFFERFYREDESHNSKEKGYGIGLSMAESMVKLFK
                     GTITVNYKNDAIVFTVVI"
     gene            6261..7139
                     /gene="mvk"
                     /locus_tag="ACF4ZO_001798"
     CDS             6261..7139
                     /gene="mvk"
                     /locus_tag="ACF4ZO_001798"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004496 - mevalonate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0016126 - sterol biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HFD5487306.1"
                     /translation="MNENIGYGKAHSKIILIGEHAVVYGYPAIALPLTDIEVVCHIFP
                     ADKPLVFDFYDTLSTAIYAALDYLQRLQEPIAYEIVSQVPQKRGMGSSAAVSIAAIRA
                     VFSYCQEPLSDDLLEILVNKAEIIAHTNPSGLDAKTCLSDHAIKFIRNIGFETIEIAL
                     NGYLIIADTGIHGHTREAVNKVAQFEETNLPYLAKLGALTQALERAINQKNKVAIGQL
                     MTQAHSALKAIGVSISKADQLVEAALRAGALGAKMTGGGLGGCMIALADTKDMAEKIS
                     HRLKEEGAVNTWIQML"
     gene            7121..>7427
                     /locus_tag="ACF4ZO_001799"
     CDS             7121..>7427
                     /locus_tag="ACF4ZO_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HFD5487307.1"
                     /translation="MDPNVITVTSYANIAIIKYWGKENQAKMIPSTSSISLTLENMFT
                     TTSVSFLPDTATSDQFYINGVLQNDEEHTKISAIIDQFRQPGQAFVKMETQNNMPTAA
                     "
BASE COUNT         2375 a         1193 c         1436 g         2423 t
ORIGIN      
        1 cttaaaagaa aatctaatca gaactcgtct ttgtccattc tttgtaatgg tttttttgtt
       61 ttcttctttt cagagatgct tctttcaaac ggagttccct cggttttttt agcactaaat
      121 atctagctta tcttcatagc ttaatgtcat gcaaaaacac cccaaacgtt agatttttta
      181 tctaacgttt ggggtgtagt ttacattatg gcgcttcttt tctattatta cgtgaggaaa
      241 aatcaagtaa aaaagttaag tcaactgaaa aacttgacag aaatattcag aaaatttata
      301 atactaacta ttaacaatat atcagttatt aaagcatttc aaacagcagg tgttttattt
      361 ggacctgtta aggctgcaaa tgcaagagaa agcagtatct ggtttgaaaa tctcacaaag
      421 caataactat ctctcttaga catttgaaga agcagacagt aaattcgata atattgtgat
      481 gagaacttag caacaatctg ctgatgcagg tcaattttta tttggtactc atattgcaga
      541 atttcataaa gttgcccaag gtatcttgaa ataaggaatc acctgatgtt ttaaacagat
      601 gatactaagt ctatcctatg gtgataatag tccattgaac atgtagttta tgaattaaaa
      661 agaaggttta aggagataag aatgattaga gaaatcataa cagatcattt tttattacag
      721 caaaaagcgc aagtcgccaa gaaagaagat ctatggattg gccaagattt acaagatacc
      781 ttagcctttt atagacagga atgtcttggg atggctgcca atatgattgg tgaacaaaaa
      841 cgcattgtta ttgtgagtat gggatttatt gatttggtta tgtttaatcc tgtgatggtt
      901 tctaaaaagg gaatttacca aactaaagaa tcttgtttgt cgttatctgg ctatcgcaaa
      961 acacagcggt atgataagat tactgttgag tatttggacc ataattggcg accaaagcga
     1021 ttaagcttaa caggcttaac tgctcaaata tgccagcacg aattagatca tctagaaggt
     1081 attttaattt aacaaaaaac ctagagtagg acgctttagg ttttttggca aagatgcctg
     1141 attatataag ggtgatcgat tactagtaaa cgctaggatt tccttttttt aataaaagcg
     1201 tttagtccac ctaagcttat caaggcaagg attgtcataa taggagacat tttataattg
     1261 tcccctgtta ttggaagagt ggaactagag atagtatttt tgtttgtcgt tgtttctttt
     1321 ttgccaaggc tgttattagt gttttcagta gaagtcaaaa ggtctgaaat gatttcacta
     1381 gacactatat tgccatcacg atttctaaaa accttactaa tgatactgtg tttaccagca
     1441 ctattaactt ttgtcgagct ttcaaggttt gaagttacat aatttttaac cccttttata
     1501 gtagcattaa cagttttacc tgatgcttct aaatttgtga tatatgtgat gaaagcttca
     1561 gtatctgtgt taatagctcc aattaattta gcttttttaa atgctgaaaa gccatcacca
     1621 ccaccataaa gaaagtcgtt gacaacaacg gtgtaagtag ttgttaagtt aatttcttca
     1681 ccattgtctt tataaacctt aactatcttg aagggggtat cagagttctt aggatcatta
     1741 tctgtataag tgtatgttaa acctgacatt tgaagaaaat aggtctggtt ttcatcgtat
     1801 tgctgattta ggacatcgta aatgtgttga ccagtcattt gaatgacttg aaggatatta
     1861 ccaaatggtt gtacagcctg tgcagctccc caggtgatgg tccggtcatt tttgacaact
     1921 aggtcacttc gaataccacc attattggtc atagcaaagt caacagttgg aaaagttttc
     1981 ttagcaatag taagctgagc cgttgttact aagttaccga caggagattc tttatcaata
     2041 ttttctgttt tagaaatagt tgaagaatta gttgcagttc cgatttttcg ttcagtaact
     2101 gttttaacaa tatcattagc atgatttatt atagctttga tatctgaatt ttctgttttg
     2161 atacctggtg ctacagcaac aacatttgct gatggagttt taataaaatc attggtatca
     2221 gtatctagcg taccacggac atctgcataa gcttttcctt gagagagggc ttgaacgata
     2281 cgtgttttac cgatagttcc attagtgtat tgatgattat gtcctgcaaa aataatatca
     2341 atgctatgtt cgggatagat ttggttcact ttttccataa ccgtagccat ttcatgatca
     2401 acaacaccat ctttacttgt tgcaggaata tgagctaaaa ccacaatagc atgaacatgt
     2461 tgttcttgca gttctttagc atatttggca atggtttcag ctacatctaa aaattgatag
     2521 tgttcatagt tttgctttaa aacgagattt ggaatctctg tagtcacaac accaatgaag
     2581 ccaatcttaa cgattttgtc attaatggct atgtctttta tagcataagg tttccaacca
     2641 taggggatat cattagtttt tttatcaatg acattagcaa tgacgatggt ttgatgcgaa
     2701 gcttcgtgct catattgttt ggtgatatcg ttaattgttg attcaggatc aggcgcttga
     2761 cctgtcatga tacggttaaa ttcatctagt ccttcgtcaa attcatgatt accaagagtg
     2821 ccatattcaa atttcatttt gttaaagact ttcacagtag gctcatcttg taaaagtgca
     2881 gagttagcag gactggctcc gaccatatct ccagcttgaa cacgtatact tgttccgtct
     2941 tgatttgctt gcttgaaatc tatctcagcg tcatccatat aagcacctaa ttgagcagcc
     3001 gtcccagcat ttggtatttt accacttggt gtgtaagctg ttccggtatt atcaagagcg
     3061 ccgtgaaaat cattgacgcc aaggaattgc acatcaactt gatctgcttg aacgtctgta
     3121 actaatagag taaaactagt caggatactc aatacactac tttttaaaat aaaatatttt
     3181 ttcataaaat ctcctaataa gttaacgtaa tcgttataga tcaagtttac tatgtttttg
     3241 tttgtaattc aatggtattt taaaaaaata acgtacaaaa aacatatgaa agcgatttaa
     3301 aagcaaacga tatagatcgt ttgcagttat atagttagaa ataaagataa ccgatcattg
     3361 cagagattta agcatttgtt gagaaaattt gttataataa gcgtatgaaa gaaagactag
     3421 aacattattc taccagctct atatatagcg gatttgaagt gtacttgccg ttggtactac
     3481 agacaataac agatgtgatt attgctgaga atatcaaaag caaaaaagaa acagggttta
     3541 aactatacga acactttaca tcccgtatta aatcggaagc ttcgatgatt gaaaaatgtc
     3601 aacgcaaaca gcttcctcta acaagcaaat ctgcgttaaa aatcattaaa gatagtatcg
     3661 gtattcgcat tatttgtggt tttattgatg atatttatcg gatggtagac ttgctcaaaa
     3721 gtattcctgg tatgtcagtt aacactgaaa aagattatat tttaaatgcc aagcctaatg
     3781 gctatagatc atatcatctc attttggaat tagaaacaca ttttccagat attttaggga
     3841 aaaaaaaggg atgttatttt atagaagtgc agttgcgaac cattgctcaa gactcttggg
     3901 ctagcttgga acatcagatg aagtacaaac atcaagttgc taatgcagaa atgattacaa
     3961 gagagttaaa gcgttgtgca gacgagttgg catcttgtga tgttaccatg caaaccattc
     4021 gtcaattgat tcaagaaacg acggaggaag agtaaccatg aaaattttat tagctgaaga
     4081 cgaatggcag atgtctaatg ttttgacaac tgccatgact catcaaggtt atgacgttga
     4141 tgtggttttt aacggtcaag aggcaattga taaagccaaa gacaatgcat atgatattat
     4201 gattttagat atcatgatgc cgattaagtc tggcattgag gctttaaagg agattcgcgc
     4261 ttcaggaaat tgctcacata ttattatgct gacggctatg gcagaaatta atgaccgtgt
     4321 taccggacta gatgcgggag ctgatgatta tctgactaaa cctttctcat taaaagaact
     4381 tttagctaga ttaaggtcga tggaaagacg agtagaaagt tttactcctc aggtattaca
     4441 atttgctggt gtcacattaa atattaatga gcaagaactg agtgccggta atgctatacg
     4501 attagcttct aaagaaggta aattaatggc ctttttaatg ttaaatcaag gaaagtactt
     4561 ggatactaaa acactttacc aacatgtttg gtcagaccaa gaagattatg atacttctat
     4621 tgtttgggtt tatatttctt atcttcgtca aaaattatta gctattcaag caaatgtcat
     4681 tattgcaggt gataaagata ctagctattg tttattagaa aaataggagg tgacatgttt
     4741 aatcgtatcc gtattcgttt tatcatgatt gcttctattg ccatttttat tattttaagt
     4801 tcaattgttg gtattattaa cacggcacgc tgttaccaaa gtcaacaaga aattaaccgt
     4861 attttacatt taatttcctc aaataaaggt aaattacctg acactacgga aagctctaaa
     4921 cgacttggaa cgaaactgtc tgaagatagc ctaagccagt ttcggtatta tagtgtcatt
     4981 tttaatgcta atggacatct actttcttct aatactgcta atatttcagc tttagataga
     5041 gaagaagccc aatattttgc tagacttttt gctaagtctg gggaagaaaa aggcagttac
     5101 cgtcaccaag atagtgttta ttcgtacttg attactcagc tgccaaatga agaaaaactg
     5161 gttgttattt tagatactac cttttatttt cgtagtgtag gagatttatt agctgtttca
     5221 atgatgttgg cctttggagg atttatcttt tttgttgttt tagtgagtct tttttccggt
     5281 atggtcatca aaccttttgt ccaaaattat gagaagcagc gccgctttat tactaatgca
     5341 ggccacgagt taaaaacacc actagccatt atctcagcca ataatgaatt ggtcgaatta
     5401 atgactggag aatcagaatg gaccaagagt acaagtgatc aggtgaagcg attgacaggc
     5461 ttgattaatc aaatgattac tttggctcgt ttggaggaac ggccagatgt ggtattacat
     5521 atggtagact tttcagctat tgctcaagat gcagctgaag attttaagag tctggttttg
     5581 aaagatggta aacgttttga tttgacgatt cagccgaata ttatgattaa agcggaggaa
     5641 aagtcattat ttgaacttgt gacaatttta gttgataatg ccaataaata ttgtgatcct
     5701 aaaggcttgg tcaaggtatc tttaaccact attggaagaa gacgaaaacg agcgaaatta
     5761 gaagtttcta atacctattt ggaaggaaaa tccattgatt acagccgctt ttttgaacgc
     5821 ttttatcgcg aagacgaatc ccataatagc aaagaaaaag gttatggaat tggtttatct
     5881 atggcagaaa gtatggttaa gttatttaaa ggaacgataa ctgtaaatta taaaaacgat
     5941 gctattgttt ttacagtggt gatttgactt aaacattttt tagtaccttt agctagtaat
     6001 aatgtctagg taaaggtaat aaacgatgct taaccagccc atgaggctgg tttttaacgt
     6061 ttaatttagt agaagagtga ttaaagaagg tagtttgaaa taagaaaatt tttgttatga
     6121 tcctaaaaag agtagatagt ctttattgtt aatttcagtg aagaaatgat tttaaaaaga
     6181 tatatcatcg cattttctaa tcatttagtg taaaatagta aggtaaaagt ttagaagaat
     6241 tagtaatgaa aagataaaaa atgaacgaaa acattggata tggtaaggca cacagtaaga
     6301 tcattttgat aggtgagcat gctgttgtgt atggctaccc agctattgct ttgcctttaa
     6361 cagatattga ggtggtttgt catatttttc cagctgataa gccattggtc tttgattttt
     6421 atgatactct atcaacagcc atttatgctg ccttggatta tttgcagcga ctacaagaac
     6481 caattgctta tgagattgtt tcacaagtgc cacaaaagcg tggtatgggg tcttcggcag
     6541 ccgtttctat tgcagctatt agagccgttt tttcttattg tcaagaaccc ctctcggatg
     6601 atttgttgga aattttagtc aacaaggcag aaattattgc ccacaccaat cctagtggtt
     6661 tagatgccaa gacatgcctt agtgaccatg ccattaagtt tatccgaaac attggctttg
     6721 aaactatcga aatcgcctta aatggttatc ttatcattgc agatacaggg attcacggtc
     6781 atacacgtga ggccgtcaat aaggtagcac agtttgagga aacgaatttg ccctatctgg
     6841 ctaaactagg agctttgaca caagcccttg aaagagcgat taaccaaaaa aataaggtgg
     6901 ctatcggtca gctcatgaca caagcgcact ctgctttaaa ggccattggc gttagcatca
     6961 gtaaggctga ccaacttgtg gaggctgccc taagagcagg tgctttaggc gctaagatga
     7021 caggcggtgg cttgggcggc tgtatgattg ccctagcaga taccaaagac atggccgaaa
     7081 aaatcagtca cagattaaaa gaagaaggag ccgtaaacac gtggatccaa atgttataac
     7141 cgtaacatcc tatgctaaca ttgctattat caaatattgg ggaaaagaga atcaagctaa
     7201 gatgattcct tcgacctcta gcatttcttt gactttggaa aacatgttca ccacaaccag
     7261 cgtttccttc ttaccagata ctgcaaccag tgatcagttt tacattaacg gtgtcttgca
     7321 aaatgacgaa gaacatacca aaatttctgc tatcattgac caatttcgcc aacctggtca
     7381 ggcttttgta aagatggaaa ctcaaaataa tatgccaaca gctgcag
//
LOCUS       DAXMQE010000060         7321 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.060, whole genome shotgun sequence.
ACCESSION   DAXMQE010000060 DAXMQE010000000
VERSION     DAXMQE010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7321)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7321)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7321
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.060"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            complement(<1..1723)
                     /locus_tag="ACF4ZO_001800"
     CDS             complement(<1..1723)
                     /locus_tag="ACF4ZO_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tex-like N-terminal domain-containing protein"
                     /protein_id="HFD5487308.1"
                     /translation="MENNNNHNIAEALSVSLHQIEQVLALTAQGNTIPFIARYRKEVT
                     GNLDEVVIKSIIDMDKSLTTLNERKATILAKIEEQGKLTDQLRTSIEATEKLADLEEL
                     YLPYKEKRRTKATIAREAGLFPLARLILQNAQNLETAAEPFVTEGFASPQEALAGAVD
                     ILVEAMSEDAKLRSWTYNEIWQYSRLVSTLKDEQLDEKKVFQIYYDFSDQVSNMQGYR
                     TLALNRGEKLGILKVSFEHNLEKMQRFFSVRFKETNPYIEEVINQTIKKKIVPAMERR
                     VRSELSDAAEDGAIHIFSENLRHLLLVSPLKGKMVLGFDPAFRTGAKLAIVDQTGKLL
                     TTQVIYPVAPASQTKIQAAKETLTQLIETYQIDIIAIGNGTASRESEAFVADVLKDFP
                     NTSYVIVNESGASVYSASELARHEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIG
                     VGQYQHDVSQKKLSENLGFVVDTVVNQVGVNVNTASPSLLAHVSGLNKTISENIVKYR
                     EENGALTSRADIKKVPRLGAKAFEQAAGFLRIPGAKNILDNTGVHPESYPAVKELFKV
                     LDIQDLDD"
     gene            1957..2112
                     /locus_tag="ACF4ZO_001801"
     CDS             1957..2112
                     /locus_tag="ACF4ZO_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPJ_0845 family protein"
                     /protein_id="HFD5487309.1"
                     /translation="MAITHKKNDELEKMLAGFASIPSFDKPLEVNTDGKLATKEKTTE
                     QTKPSKP"
     gene            2260..3162
                     /locus_tag="ACF4ZO_001802"
     CDS             2260..3162
                     /locus_tag="ACF4ZO_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HFD5487310.1"
                     /translation="MSLFSNLPPSVLQWFAIFMSIIIEALPFVLLGTILSGCIEVFVT
                     PELVQKYLPKQKCLRILFGTFVGFVFPSCECGIIPIINRFLEKKVPSYTAVPFLATAP
                     IINPIVLFATYSAFGNSLRFLILRLVGAALVAITLGVMLAFIVDDNILKDNAQPVHFH
                     DYSHESLPKRIYLALVHAIDEFFDTGRYLVFGTLIASAMQIYVPTRVLTTIGHNPLTA
                     ILIMMLMAFILSLCSEADAFIGASLLSTFGVAPVIAFLLIGPMVDIKNLMMMVKAFKG
                     RFIVQFIGVSVLMIAVYCLLVGVL"
     gene            3162..3977
                     /locus_tag="ACF4ZO_001803"
     CDS             3162..3977
                     /locus_tag="ACF4ZO_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HFD5487311.1"
                     /translation="MIRFLILAGYFELTMYLQLSGKLDQYINVRYSYLAYISMILSFI
                     LALVQLYTWMKNIKVHSHLTGKIARLTSPFILVFPVLIGLLVPTVTLDSTTVSAKGYT
                     FPLAAGASKTGVSDDGTTIQYLKPDTSLYFTKSAYQKEMRQELHKYKGKKPVTITTEN
                     YMEVMELIYLYPDEFVDRDIQYTGFVYNEPGHDNYQFLFRFGIIHCIADSGVYGLLTT
                     GNQTSYPNNTWLTVKGRLHMEYDKNLEQHLPVLQLAEVHQTKEPNNPYVYRVF"
     gene            complement(4076..5500)
                     /locus_tag="ACF4ZO_001804"
     CDS             complement(4076..5500)
                     /locus_tag="ACF4ZO_001804"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFD5487312.1"
                     /translation="MGIFPKDFLWGGAVAANQVEGAFEADAKGLSVQDVLPNGGLGEW
                     TDSPTSDNLTLEAIDFYHRYKEDIALFAEMGFKVFRTSIAWSRIFPNGDDDQPNEAGL
                     QFYDDLFDELLNYGIEPLVTLSHYETPLHLAKAYNGWTDRRLIGFFERFAQTVMERYK
                     GKVKYWLTFNEVNSILHMPFTSGGIMTEKEKLSLQDLYQAIHHELVASASVTKLAHEI
                     NPDVKVGCMILAMPAYPMTSDPRDILAAHAFENLNLLFSDIHVRGKYPSYIKSYFKEN
                     GIEIVFEDGDKELLAEHTVDFLSFSYYMSVTQAHNPEAYTSGQGNILGGLSNPYLESS
                     EWGWQIDPIGLRLVLNQYYDRYQIPLFIVENGLGAKDQLVQTADGSMTVHDDYRIDYM
                     SQHLVQVAKAIEDGVEVMGYTAWGCIDCVSMSTAQLSKRYGFIYVDRNDDGTGQLTRY
                     KKKSFDWYRQVIQTNGRYLEDNFS"
     gene            complement(5519..>7321)
                     /locus_tag="ACF4ZO_001805"
     CDS             complement(5519..>7321)
                     /locus_tag="ACF4ZO_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HFD5487313.1"
                     /translation="QRVTHCVTRLRLVLKNDEKVKDQQVKAISNVIGVMRKNGQYQII
                     LGNDVNNYYQAFLSLGHFDNQDEDHSSKAKGSILERLIETIAGVITPLIPALLGGGML
                     KVVGILLPMLGLASADSQAVAFINFFGDAAYYFMPVMIAYSAAARFKVTPVLAATIAG
                     ILLHPAFVAMVAEGKPLALFGAPVTPASYGSSVIPILMMVYLMQYIEKWVNRLVPSVM
                     KSFLQPTLIILISGFLALVVVGPLGVIIGQGLSNTMLTIYHVAPWLALAILGAIMPLV
                     VMTGMHWAFAPIFLAASVATPDVLILPAMLASNLAQGAASLAVAFKTKQKQTRQVALA
                     AGISALLAGIAEPALYGVTLKFKKPLYAAMISGGLVGAFIGFVNIASYTFVVPSIIGL
                     PQYINPSSGANFTNALIAGAATIVLAFSLTWFMGIDEESPEQVSVAADMSQVKSGLST
                     KQTLYAPMTGEMLFLSEVPDETFSSKLLGEGFAILPSEGVVYAPFDGEVITFFPTKHA
                     VALKNTRGVEVLIHVGIDTVELKGQGFEQLVSVGDVVKRGQALLKMDIDFITSKGYSL
                     ISPVVVTNSAEQLEIIIQDDKKMVTKEDALLVIL"
BASE COUNT         2127 a         1623 c         1400 g         2171 t
ORIGIN      
        1 cgtcgtccaa gtcctgaata tcaagtacct taaagagttc tttgactgct gggtaggact
       61 cggggtgaac tcctgtgttg tctaaaatat ttttggctcc tggaattctg agaaaacctg
      121 ctgcttgctc aaacgcctta gctcctaaac gcggcacttt tttgatgtca gcgcgtgatg
      181 tcaatgctcc attttcttcg cggtatttga caatattttc tgaaatcgtt ttgttcaaac
      241 ctgacacatg tgctaataaa gatggactag ccgtgttcac attaacaccg acttggttaa
      301 ccacagtatc cacaacaaaa ccaagattct cactcaactt tttctgactc acatcgtgct
      361 ggtactgacc gacgccaata gatttaggat caattttaac caattctgct agtgggtctt
      421 gcaagcgacg agcaatagaa atagcagagc gcttctccac tgtgaggtct ggaaactcat
      481 gacgggctaa ctctgacgct gaataaacag aagctccgct ttcgttaacg atgacatagg
      541 acgtatttgg gaaatctttc aaaacgtctg ctacaaaggc ttcactttcc cgactggctg
      601 ttccgtttcc aatggcaata atatcaatct ggtaagtctc aatgagctga gtcagtgttt
      661 ctttagctgc ttgaatcttc gtttggctag ctggtgctac gggataaata acctgagtag
      721 tcaacaattt tccagtctga tcaacgatag ccaattttgc acctgttcga aaggcagggt
      781 caaacccaag aaccattttc ccttttaaag gagacactaa caaaagatga cggagatttt
      841 cagaaaagat gtggatagcc ccatcttctg cggcatcact gagttctgaa cgaacccgtc
      901 tttccatagc tggaacaatt ttctttttga tggtctgatt gatgacctct tcaatataag
      961 ggttggtttc tttgaaccgc acactgaaaa agcgttgcat tttctccagg ttatgctcaa
     1021 aagacacttt taagatgcct aacttttcgc cacggttaag ggctaaagta cgatatcctt
     1081 gcatgttaga cacttggtca gaaaaatcgt aatagatttg gaaaaccttt ttctcatcca
     1141 actgctcatc tttaagcgtt gatactaagc ggctgtactg ccaaatctca ttgtaggtcc
     1201 aagagcgtaa tttagcatct tctgacatgg cctccacaag gatgtccaca gctcctgcta
     1261 gagcttcttg tgggctggca aatccttctg tgacaaaggg ttctgctgct gtttcaaggt
     1321 tttgcgcatt ttgtaaaatc aaacgtgcta atgggaacaa gcctgcttca cgcgcaatcg
     1381 tcgcttttgt acggcgtttt tccttataag gcaggtacaa ctcttccaaa tcagcgagtt
     1441 tctcggttgc ttcaatactc gttcgtaact gatctgtcag ttttccctgt tcctcaattt
     1501 tagcgagaat ggttgctttg cgctcattca gggtagtaag agacttatcc atatcaataa
     1561 tggacttaat caccacttca tctagatttc ctgttacttc tttacggtaa cgtgcaataa
     1621 agggaatggt attgccttgt gctgttaggg caagcacctg ttcaatttga tggagactaa
     1681 ctgacaaagc ctctgcaatg ttgtgattat tgttattttc cataatattg ctattataac
     1741 acaaaccatg ttaatgcaaa aaatgatagc gaaacattgt cctaatataa agttgcgtaa
     1801 agaatcaaaa aaagctactt ttagtaaata actgacgaaa ccctaaataa caatacctaa
     1861 ttttaaaaaa gaaagaagta aacaacactt ccgttttggc attgttctca aatgatagta
     1921 taatagactt atcttgaatg aaagaaggtc atagatatgg caattaccca taaaaaaaat
     1981 gatgaacttg aaaaaatgct agcaggcttt gcatcaatcc ctagttttga taagcctttg
     2041 gaagtcaata ctgatggtaa actagcaacc aaagaaaaaa cgacagaaca aacaaaacca
     2101 agcaaaccat agctagtttg tttcattctc ttaacatatc gtccattcgt ttaaactgag
     2161 ttgagagatt tttagcgatc aggctaacaa aacgtatcag tcgaggctga acattcgtgt
     2221 ttcagcctcc tcttttatca tctagaaagg atatggtgaa tgtcactctt ttccaacctt
     2281 cctcccagtg tcttgcaatg gtttgcgatt tttatgtcca ttatcattga agctcttcct
     2341 tttgtgctcc taggaactat tttatctggt tgtattgaag tctttgtaac gccagaattg
     2401 gttcaaaaat acctacctaa gcaaaaatgc ttgcgcattc tgtttggaac ctttgttgga
     2461 tttgtttttc cttcttgtga atgcgggatt attcccatca tcaaccgctt tttggaaaaa
     2521 aaggtgccta gttatacggc cgtccctttt ctggcaacag cgcctattat taatcctatt
     2581 gttttgttcg ctacttattc tgcttttggg aattctttgc gctttctgat acttcgcttg
     2641 gtcggtgctg cactagtagc cattacactt ggggtaatgt tagcttttat tgtagatgat
     2701 aacattctca aggataatgc tcaacccgtg cattttcatg attattctca tgaaagcttg
     2761 ccaaaacgca tttatctagc actggtacat gctattgatg aattcttcga caccggtagg
     2821 tatctcgtat ttggaacctt gattgcctct gccatgcaaa tatatgtccc aactcgtgtg
     2881 ttgacaacga ttgggcacaa tcccttgaca gccattttga tcatgatgct gatggctttc
     2941 attctatcat tatgtagtga agccgatgcc tttatcggag cttccttatt atccaccttt
     3001 ggagtggctc cagttattgc ctttctttta attggtccta tggtggatat taaaaacctt
     3061 atgatgatgg taaaggcttt taaaggacgc ttcattgtcc aatttatcgg cgtatccgtt
     3121 cttatgattg ccgtttattg tttacttgtg ggggtgctct aatgattcgc tttttaattt
     3181 tagctggcta ttttgaacta accatgtatc tccagctgtc tggcaaactg gatcagtaca
     3241 tcaatgttcg gtattcttac cttgcttata tttccatgat tttatctttc attttagctc
     3301 ttgttcaact ctatacctgg atgaaaaaca ttaaggtaca tagccattta accggaaaaa
     3361 tcgcaaggct gaccagtcct tttatcttgg tctttcctgt tttgattggt ctccttgtgc
     3421 caacagtaac cctagattcc accacggttt ctgctaaagg ctatactttc ccattggctg
     3481 cgggagcctc taaaacggga gtcagtgatg acggtaccac cattcaatac ctcaaacctg
     3541 acaccagcct ttactttaca aagtctgcct accaaaagga gatgcgtcaa gaactccata
     3601 aatataaagg caagaaaccg gtcactatta ccactgaaaa ttatatggaa gtgatggaat
     3661 tgatctatct ctacccagat gagtttgttg atcgtgacat ccaatacact ggctttgttt
     3721 ataacgaacc gggccatgat aactaccaat tccttttccg cttcggcatt attcactgta
     3781 ttgccgactc aggagtgtac ggacttttga ccacaggtaa tcaaaccagc taccctaaca
     3841 acacatggct aacagttaaa ggtcgccttc atatggaata tgataaaaac ttagaacaac
     3901 atctacctgt ccttcaactt gctgaggttc atcaaaccaa agagcctaat aatccttatg
     3961 tttaccgcgt tttttaaaga ctaataaaaa agcacttgtt ttttatcaaa acaaatgctt
     4021 tttgcgtttt atcagttagc ataggaacag agtcaccatc ttaaacaaga cctatttagg
     4081 aaaaattatc ctcaaggtaa cgtccattgg tttgaatgac ttgtcggtac caatcaaatg
     4141 attttttctt atagcgtgtg agttgaccag taccatcatc atttcggtca acataaataa
     4201 aaccgtagcg cttacttaat tgggctgttg acatagagac acaatcaata cagccccaag
     4261 cagtgtaacc catgacctca acgccatctt caatcgcttt ggcaacttgt acgagatgct
     4321 gactcatgta gtcaatgcga taatcatcgt gaaccgtcat gctgccatct gcggtttgca
     4381 ccagctgatc ctttgcacct aagccatttt caacaataaa caaaggaatc tggtagcggt
     4441 catagtactg attcaagacc aatcgcagac caattgggtc tatctgccaa ccccactccg
     4501 aagattctaa atatggattg gacaaaccac ctagaatatt tccctgacca gatgtgtaag
     4561 cttcaggatt gtgagcttgt gtgacactca tgtaatagct aaaggataga aaatcaaccg
     4621 tatgttccgc taataattcc ttgtctccgt cttcaaaaac aatctcaatc ccattttctt
     4681 taaaatacga cttaatatat gaaggatact tgcctctcac atgaatatct gaaaataaga
     4741 gattaagatt ttcaaatgca tgcgcagcaa gtatatcacg aggatcagag gtcattgggt
     4801 aagcaggcat cgccaaaatc atacacccaa ctttaacatc aggattgatt tcatgcgcta
     4861 gctttgtgac actagcagat gctaccaatt catgatgaat agcttggtat aaatcttgca
     4921 ggctcagctt ttctttttct gtcatgatgc caccactggt aaagggcatg tgtaaaatcg
     4981 agttgacttc gttgaaggtc aaccagtatt tgactttgcc cttatagcgt tccatgactg
     5041 tctgagcaaa gcgctcaaaa aagccaatca gacgtctatc tgtccaacca ttataggctt
     5101 tggccaaatg cagaggtgtc tcataatgcg acaaggtcac taagggttcg atgccatagt
     5161 tcaacaattc atcgaataag tcatcataaa attgcaaacc tgcttcattg ggctggtcat
     5221 cgtcaccatt tggaaaaata cgagaccaag caatagacgt tcgaaagact ttaaagccca
     5281 tctcggcaaa aagagcaatg tcttctttgt agcggtggta aaaatcaatc gcctctaaag
     5341 ttaaattatc gctggtagga ctatctgtcc attctcctag tccaccattt ggtagaacat
     5401 cttgtacgga caaacctttt gcgtctgcct caaatgctcc ttccacttgg ttggcagcta
     5461 ctgcgccgcc ccataagaaa tcttttggaa aaattcccat tctccctctc cttttaggtt
     5521 ataaaatgac taacaaagcg tcctctttag tcaccatttt tttgtcatct tgaataataa
     5581 tctccaactg ctcagccgaa ttggtcacga ccacaggact gatgagtgaa tagccttttg
     5641 aagtaatgaa atcaatatcc atttttagaa gtgcctggcc tcgtttcacg acatcgccaa
     5701 cagacactaa ctgctcgaaa ccttgccctt ttaactcaac cgtatcaata ccgacatgaa
     5761 tcaagacttc cacaccacgt gtgtttttta aggcaacagc atgcttggtt ggaaagaaag
     5821 tgatgacttc accatcaaag ggggcataga ccacaccttc gcttggtaat atggcaaatc
     5881 cttctcctaa taacttggaa gaaaaggttt catcaggaac ttctgataga aaaagcatct
     5941 cacctgtcat tggagcatac aacgtttgtt tggttgacaa gccgctctta acttgtgaca
     6001 tatctgctgc aacactcact tgctctgggg attcttcatc aattcccatg aaccaagtca
     6061 aactgaaggc taacacaatc gtcgcagctc cggcaatcaa agcatttgta aaattagctc
     6121 cgcttgatgg gttgatgtac tgtggtaaac caataataga aggtacgaca aaggtataag
     6181 aagcaatatt gacaaaacca ataaaggctc cgaccagacc acctgaaatc atggctgcat
     6241 agagtggctt tttaaatttc agtgtgaccc cataaagtgc cggttccgcg atacctgcca
     6301 gcaaagctga aatccccgcg gcaagggcaa cttgacgtgt ttgtttctgc tttgttttaa
     6361 aggcaacagc caaagatgcg gctccttgag ccaaattaga agccaacatt gctggtaaaa
     6421 tcaagacatc tggtgttgcg accgaagcgg ccaaaaagat tggtgcaaaa gcccagtgca
     6481 tccccgtcat gacaacaagc ggcataatcg ctcccaaaat ggcaagtgct agccacggag
     6541 ccacatgata aatagtgagc atggtattag ataacccttg accaataatc acaccaagag
     6601 gacctacaac cactaaagcc aaaaagccag aaatcaaaat gattaaggtt ggctgtaaga
     6661 agcttttcat cacgcttggc accaagcgat tgacccattt ttcaatgtat tgcatcaagt
     6721 aaaccatcat caaaatggga ataacagatg agccatagct agcaggagtg actggtgctc
     6781 caaataaagc caatggttta ccttctgcta ccattgcaac aaaggctgga tgcaataaaa
     6841 tccctgcgat cgtcgctgct aaaacaggtg tcaccttaaa gcgcgccgct gctgaatagg
     6901 caatcatgac aggcataaaa taataagccg catcgccaaa gaagttaata aaggcaacgg
     6961 cttgagagtc cgcactcgct aagccaagca taggaagcaa gattcccacc actttgagca
     7021 ttccaccacc aagaagggct ggaatcagcg gtgtaatcac accagcaatg gtttcaatca
     7081 agcgctcaag gatacttcct tttgcttttg aagaatgatc ttcatcttga ttgtcaaaat
     7141 gccctaggct taaaaaggct tggtaataat tattgacatc attgcccaag ataatttggt
     7201 actggccgtt tttgcgcatc acgccaatca catttgaaat ggctttgact tgctgatctt
     7261 taactttctc atcatttttc agtactaagc gtagacgtgt tacacagtgt gtcacacgtt
     7321 g
//
LOCUS       DAXMQE010000061         6493 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.061, whole genome shotgun sequence.
ACCESSION   DAXMQE010000061 DAXMQE010000000
VERSION     DAXMQE010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6493)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6493)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6493
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.061"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            <1..1212
                     /gene="glmM"
                     /locus_tag="ACF4ZO_001806"
     CDS             <1..1212
                     /gene="glmM"
                     /locus_tag="ACF4ZO_001806"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008966 - phosphoglucosamine mutase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HFD5487314.1"
                     /translation="DTRISGEMLESALIAGLLSVGIEVYKLGVLATPGVSYLVRTEKA
                     SAGVMISASHNPALDNGIKFFGNDGFKLADDQELEIEALLDAPEDTLPRPSAEGLGTL
                     VDYPEGLRKYEKFLVTTGTDLSGMTVALDTANGAASVSARDVFLDLNAEIAVIGEKPN
                     GLNINDGVGSTHPEQLQELVKETGADLGLAFDGDSDRLIAVDETGEIVDGDRIMFIIG
                     KYLSEKGLLAHNTIVTTVMSNLGFHKALDKQGINKAITAVGDRYVVEEMRSSGYNLGG
                     EQSGHVIIMDYNTTGDGQLTAIQLAKVMKETGKSLSELAAEVTIYPQKLVNIRVENSM
                     KDRAMEVPAIANIIAKMEDEMAGNGRILVRPSGTEPLLRVMAEAPTDAEVDYYVDTIA
                     DVVRTEIGCDN"
     gene            1336..1977
                     /locus_tag="ACF4ZO_001807"
     CDS             1336..1977
                     /locus_tag="ACF4ZO_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5487315.1"
                     /translation="MTKQQIEKLADLLPPFAATLYLDMIPEFQEGYASYVYQTQKEDI
                     QKRRIKQLTKNFERLLDTPSFYVMPVTRKTAEQLLADKGLAYHLLSTVAANQVFAAAV
                     NEDQTLFQVLRNGARVAFVILQEKGEFLEMTLGILETVTENEVPAAIVEAVQTYLLTD
                     MQEKLPSLSIMVSQESSKLFYQEQGFVLLAKGCKPGNENDSDVCQLVKYFSKP"
     gene            2040..3170
                     /gene="hemW"
                     /locus_tag="ACF4ZO_001808"
     CDS             2040..3170
                     /gene="hemW"
                     /locus_tag="ACF4ZO_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0051989 - coproporphyrinogen dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM family heme chaperone HemW"
                     /protein_id="HFD5487316.1"
                     /translation="MSKKPTSAYVHIPFCTQICYYCDFSKVFIQNQPVDAYLKALIQE
                     FDSYGIRDLKTLYIGGGTPTAITAKQLEYLLNHLERNLNLDDLEEFTIEANPGDLTPE
                     KIAVLQRSAVNRISLGVQTFNNKQLKQIGRSHNEEQIYSTIANLKTAGFHNISIDLIY
                     ALPGQTLDQVKENVAKALALDIPHLSLYSLILEHHTVFMNKMRRGKLNLPTEDLEAEM
                     FEYIISEMEANGFEHYEISNFTKPGFESRHNLMYWDNVEYFGCGAGASGYLNGIRYQN
                     RVPIQHYLKAVEAGNARLNEEVLRKEEMMEEELFLGLRKKTGVSIQRFQEKFGVSFEE
                     RYGNIVRELQNQGLLVKDDAFVRMTKKGLFLGDSVAERFILD"
     gene            3180..3932
                     /locus_tag="ACF4ZO_001809"
     CDS             3180..3932
                     /locus_tag="ACF4ZO_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-ACP thioesterase domain-containing protein"
                     /protein_id="HFD5487317.1"
                     /translation="MGLSYQEELILPFELCDVKSDIKLPLLLDYCLMVSGRQSAQLGR
                     SNNNLLVDYKLVWIVTDYEITIHRLPHFQETITIETKALSYNKFFCYRQFYIYDQEGD
                     LLVDILAYFALLNPDTRKVATIPEDLVAPFKTDFVKKLHRVPKMPLLEQSIDRDYYVR
                     YFDIDMNGHVNNSKYLDWMYDVLGCAFLKTHQPLKMTLKYVKEVSPGGQITSSYHLDQ
                     LTSYHQIISDGQLNAQAMIEWRAIKQTESETD"
     gene            3932..4696
                     /locus_tag="ACF4ZO_001810"
     CDS             3932..4696
                     /locus_tag="ACF4ZO_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HFD5487318.1"
                     /translation="MPYKGYLIDLDGTIYQGKNRIPAGERFIKRLQERGIPYLLVTNN
                     TTRTPEMVQSMLANQFHVETGIETIYTATMATVDYMNDMNRGKTAYVIGETGLKSAIA
                     AAGYVEELENPAYVVVGLDSQVTYETLAIATLAIQKGALFIGTNPDLNIPTERGLMPG
                     AGALNALLEAATRVKPVFIGKPNAIIMNKSLEVLGIQRSEAVMVGDNYLTDIMAGIQN
                     DIATILVTTGFTRPEEVPTLPIQPDHVLSSLDEWRL"
     gene            4696..5328
                     /locus_tag="ACF4ZO_001811"
     CDS             4696..5328
                     /locus_tag="ACF4ZO_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HFD5487319.1"
                     /translation="MVENTKLLCSWVWLLALAILITIYSTWLWYPLEVDHLKLEQVVF
                     MSKDAILHNYNGLLNYLINPFVTRLEFANFHSSADGLKHFADVKWLFHLTQVVFLGLL
                     YPTLKTFTQRLKTKRFWLLQKPLILAALFPLMIGLMASFIGFEHFFTLFHKVLFVGDS
                     SWLFDPLKDPVIWILPEVFFLHCFLFFMIVYEIILWSLVGLARWQRLNVE"
     gene            5630..6090
                     /locus_tag="ACF4ZO_001812"
                     /pseudo
     CDS             5630..6090
                     /locus_tag="ACF4ZO_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051153.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
     gene            6160..>6493
                     /locus_tag="ACF4ZO_001813"
     CDS             6160..>6493
                     /locus_tag="ACF4ZO_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HFD5487320.1"
                     /translation="MNSQDLKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVV"
BASE COUNT         1950 a         1169 c         1424 g         1950 t
ORIGIN      
        1 gacacccgta tttcaggaga aatgttggag tcagccttga ttgctggtct actatctgtt
       61 ggtattgaag tttataaact tggtgtttta gcgacacctg gtgtctctta tttagttaga
      121 actgaaaaag caagtgcagg tgtgatgatt tctgcaagtc ataaccctgc gcttgacaat
      181 ggcatcaaat tctttgggaa tgacgggttt aagttagctg atgaccaaga attggaaatt
      241 gaagctctct tagatgctcc ggaggacacg cttcctcgcc cgagtgcaga aggacttgga
      301 accttggtag attatccaga aggacttcgt aaatatgaaa agttcttggt aacaacaggt
      361 actgacttaa gcggtatgac agttgcctta gacactgcta atggagctgc ttcagtgtca
      421 gcacgtgatg tctttttaga tttaaatgca gaaattgctg tcattggcga aaaaccaaat
      481 ggtcttaata ttaatgacgg tgttggttca acgcatccag aacaacttca agagttagtt
      541 aaggaaacag gagcagatct tggtttagcc tttgacggcg atagcgaccg tctgattgct
      601 gtggacgaaa ctggcgagat tgttgacggt gatcgtatta tgtttatcat tggtaaatac
      661 ttgtcagaaa aagggcttct tgctcacaat accattgtca caacggtgat gtctaacctc
      721 ggttttcata aagctttaga taaacaaggt attaataaag caattacagc agttggagac
      781 cgctatgtgg ttgaagaaat gcgtagctca ggatacaatc tcggtggtga acaatcaggc
      841 catgtcatta tcatggacta caataccact ggagatggtc agttgacagc tatccaatta
      901 gccaaggtga tgaaggaaac tgggaaatca ctttcggaat tagctgctga agtaaccatt
      961 taccctcaaa aactggtgaa tattcgtgtg gaaaacagca tgaaagaccg tgctatggaa
     1021 gttccagcta ttgcgaacat cattgcaaaa atggaggatg aaatggctgg taatggtcgt
     1081 attctcgtga gaccaagtgg tacagaacct cttcttcgtg tcatggcaga ggcgccaaca
     1141 gatgccgaag ttgattatta tgtcgatact attgctgatg tcgtccgtac agaaatcgga
     1201 tgcgataact aacgagttga gtacaaacaa gaaaccttat ttctaaggct tctgtcaaca
     1261 attggaaaga ggcttggggc gtttagccca agtctctttt tataaattac taaagtagaa
     1321 gagaaaggat atcggatgac aaaacagcaa atcgaaaaac tagcggactt actgcctcct
     1381 tttgcagcca cactttactt agatatgatt cctgaatttc aggaaggtta tgcttcatat
     1441 gtttatcaaa cccaaaaaga agatattcaa aagcgccgca tcaagcagtt aactaaaaat
     1501 tttgaacgat tactagatac cccatctttt tatgtgatgc ctgtgacaag aaaaacagca
     1561 gagcaattgc tagcagataa aggcctagct tatcatttgt tatcgacagt tgcagctaat
     1621 caagtgtttg cggctgctgt taacgaggat cagacgcttt ttcaagtgct tcgaaatgga
     1681 gcaagagtag cctttgtgat tcttcaagaa aagggggaat ttctagaaat gactttaggg
     1741 attcttgaaa cagtgacaga aaacgaggtt ccagcagcta ttgtggaggc tgtccagaca
     1801 tatcttctga cagatatgca agagaaactc ccttctttaa gcattatggt cagtcaagaa
     1861 tcaagcaagc ttttttacca agaacaaggg tttgttttgc tagctaaggg ttgcaagcca
     1921 ggaaacgaaa atgactctga cgtttgtcag ctcgtaaaat acttttccaa gccatgaaga
     1981 atcaagggaa atggtttatt cataaaaaca ttttatcacc aaagtggtat aataagacca
     2041 tgtcaaaaaa acctacttca gcctatgtgc acattccttt ttgcacacaa atttgttatt
     2101 attgcgattt ttcaaaagtc tttatccaaa atcaacctgt tgatgcttat ttgaaagcct
     2161 tgattcaaga atttgactct tatggcattc gagacctaaa aaccctttat attggaggag
     2221 gtacgcctac agctatcact gctaaacagt tggagtatct cctaaatcac cttgaacgaa
     2281 acctcaattt agatgatctt gaagaattca caattgaggc aaatcctggt gatttgacgc
     2341 cagaaaaaat tgcggtgctt cagaggtcag ctgtcaatcg gatttccttg ggggtgcaga
     2401 cttttaataa caagcaatta aagcagattg gccgtagcca taatgaagaa caaatttata
     2461 gcaccattgc caatttaaaa actgcaggct ttcacaatat ttccattgat ttaatttatg
     2521 ccttgccagg tcaaacctta gatcaagtca aggaaaatgt tgctaaagct ctggcacttg
     2581 atattcccca ccttagtctt tatagcctta ttttggaaca tcacactgtt tttatgaaca
     2641 aaatgcgacg tggtaaactt aacttaccaa cggaagactt ggaagcggaa atgtttgagt
     2701 atattatttc agaaatggaa gctaatggct ttgagcatta tgaaatttcc aattttacca
     2761 aacctggttt tgaaagtcgt cataacttga tgtattggga taatgtggag tattttggat
     2821 gtggtgcagg ggcttcaggt taccttaatg gcattcgtta tcaaaatcgg gtgcccatcc
     2881 agcattatct taaagcggtt gaagcaggga atgctagact aaatgaagaa gtgctgcgca
     2941 aagaggaaat gatggaagag gaactctttt tgggcttacg taaaaagaca ggagtctcca
     3001 tccagcggtt ccaagaaaaa tttggtgttt cttttgagga gcgttatgga aatattgtta
     3061 gggagcttca aaaccaagga ctgcttgtca aagatgacgc ttttgtcaga atgactaaaa
     3121 agggtctttt cttaggtgat tctgttgctg agcggtttat attagattag gagagtatta
     3181 tgggattaag ttatcaggag gagttgatac ttccttttga attatgtgat gtcaaatcag
     3241 atataaaatt gcccctttta ttagactatt gtttgatggt ttctggtaga cagtctgcgc
     3301 aattaggacg aagtaacaac aatcttttag tcgattacaa gcttgtttgg attgtaacgg
     3361 attatgagat cactattcat cgcttgccac attttcaaga aaccatcacc attgaaacaa
     3421 aagccctctc ctacaataaa tttttttgtt atcgccaatt ttatatttat gatcaagagg
     3481 gggatctttt agtggatatc ttagcctatt ttgctttgtt aaacccagat acgcgaaaag
     3541 tggcaactat tccagaagat ttagtagcgc cttttaagac tgattttgtt aaaaagctac
     3601 accgtgttcc taaaatgcct cttttagaac aatcaattga tcgtgattat tatgtgcgtt
     3661 attttgatat tgatatgaat ggtcatgtca acaacagtaa atatttagat tggatgtatg
     3721 atgtgttggg gtgtgcgttt ttaaaaacgc atcagcctct taagatgact ttgaaatatg
     3781 ttaaagaagt ctcaccaggc ggtcaaatta cttccagtta ccatttggac caattaactt
     3841 cttaccatca aatcatctca gatgggcagc tgaatgccca agccatgatt gaatggcgag
     3901 cgattaaaca aacagaaagc gagacagact agtgccttat aagggttatt taattgattt
     3961 agacggaacg atttaccaag ggaaaaaccg tattccagca ggggagcggt ttatcaaacg
     4021 cctacaagaa agaggcattc cctatttatt agtgactaat aataccacaa gaacacccga
     4081 aatggtgcaa agcatgctgg ctaatcagtt tcatgttgag acaggcattg agaccattta
     4141 tacggctacc atggcaaccg tcgattacat gaatgacatg aaccgtggca agacagctta
     4201 cgttattgga gaaacagggc tcaaatcagc gattgcagca gcaggttacg tagaagaact
     4261 tgagaatccc gcttacgtgg tggttggttt agacagtcag gtgacctatg agacgttggc
     4321 tatagccacc ttggctattc aaaaaggtgc cctctttatt gggacaaatc ctgatttaaa
     4381 cattccaacc gaacgtggtt tgatgccagg agcaggtgca ttgaatgcct tactagaagc
     4441 tgccacacgt gtaaaacctg tttttattgg caagcccaac gctatcatta tgaataaatc
     4501 actagaggta ttgggcattc agcgctctga ggctgtcatg gttggcgata attacttgac
     4561 tgatatcatg gcaggtattc aaaatgatat tgcaacgatc ctcgtgacaa caggctttac
     4621 cagacctgaa gaggtaccaa ccttaccaat tcagccagat catgtcctat ctagtcttga
     4681 tgagtggagg ttgtgatggt agaaaacact aaattactat gtagctgggt atggttatta
     4741 gcgttagcta ttctcataac gatctattca acgtggctgt ggtatcctct tgaggtggac
     4801 catctaaagt tagaacaagt tgtttttatg agcaaggatg ctatcttgca taactataac
     4861 ggactactaa attaccttat caatcctttt gtaacaaggt tggaatttgc taattttcac
     4921 tcatcagcag acggactcaa gcattttgca gatgtgaagt ggctttttca cctaactcaa
     4981 gtcgtttttc ttggcctcct ttacccaacc cttaagactt tcacacaaag gttaaaaacc
     5041 aaacgtttct ggctccttca aaaaccttta atactagcag ctttgtttcc tcttatgatt
     5101 ggtctaatgg ctagtttcat tgggtttgaa cattttttta ctctttttca taaggtgctt
     5161 tttgtaggag atagcagctg gctctttgat cccttgaaag atcctgtgat ttggatcctt
     5221 ccagaagtct ttttcttgca ctgtttcctt ttctttatga tagtttacga aatcatcctg
     5281 tggagcttag taggtttagc aagatggcag cgcctaaatg tagaatgata aaaggattaa
     5341 gagattaatt tccctaaaaa tgataaaaca agcgttttga aagcgcttgt tttttgggtt
     5401 tgcagtcaga gtagaataga agtatcaaaa aaagcaccga ctcggtgcca ctttttcaag
     5461 ttgataacgg actagcctta ttttaactgg ctatgctgtt ttgaatggtc tccattcaac
     5521 attgccaatg ataacttgag aaagagggtt aataccagca gtcggatacc ttcctattct
     5581 ttctgttaaa gcgtttttat gttataatag gcaaaagaag agtagagtga tggaacaaac
     5641 attttttatg attaagccag atggggttaa gcgagggggt tagttggaga gattttgcgg
     5701 tggattgaac gcctaggatt tacgtttgag cgattcgagc taagacaagc tagttcgaaa
     5761 tacttggcta agcacgacga gaccttggtg ataaaccttt tgatcctaaa cttaaagctt
     5821 acatgacaag tggtcctgtt ttaattggga cacttcttgg ggactaaggt ggttttgtct
     5881 ttttgaacca tgatgagagt aaccaatcct acggatgctc tttgcggaat cattcgaggg
     5941 aattttgctc aggctcttag tgatgattgg gaaattttta gcatggtgca taggtcttat
     6001 tcaagagact ctgctaggcg tgagattgtc ctttggtctc atcaaagaaa tctcggtagc
     6061 tccgctattc tcttgcaaga taatccgtaa gaaaagatag gcaaaggcct accttttttg
     6121 ttataataga aggaaagact aaatgtatag gaaaatagaa tgaacagtca agatttaaaa
     6181 aaacgtcagg agaagattcg taatttctcc attattgcac atattgacca tggcaaatct
     6241 actctcgctg accgcatttt ggaaaagaca gagacggttt cgtctcgtga aatgcaggct
     6301 cagttattgg actccatgga tttggagcgt gagcgtggga ttaccatcaa gttaaacgcc
     6361 attgagctta attacacggc taaagatggg gaaacctaca ttttccacct tattgatacc
     6421 ccagggcatg tggactttac ttatgaagta tcgcgttcgt tggcagcctg tgagggagcg
     6481 attctagttg tgg
//
LOCUS       DAXMQE010000062         6454 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.062, whole genome shotgun sequence.
ACCESSION   DAXMQE010000062 DAXMQE010000000
VERSION     DAXMQE010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6454)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6454)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6454
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.062"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            41..325
                     /locus_tag="ACF4ZO_001814"
     CDS             41..325
                     /locus_tag="ACF4ZO_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HFD5487321.1"
                     /translation="MSKKKIGMISGIFGFSLAIGLGVVIKDYCQDRQRRQMTRDLRTF
                     FSPLGQIEVLYINPCQVKQDYISGGVVMSNGKQYQFTYHSRQISFEEDKG"
     gene            322..639
                     /locus_tag="ACF4ZO_001815"
     CDS             322..639
                     /locus_tag="ACF4ZO_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HFD5487322.1"
                     /translation="MIRPTSYESLAALIEKEDKLVLFFTADWCPDCQFIYPIMPEIEA
                     ELTDMTFVCVNRDQFIEVAQKWDIFGIPSFVVIEKGQEVGRLVNKMRKTKTEIMHFLA
                     AYQ"
     gene            657..1283
                     /gene="ytpR"
                     /locus_tag="ACF4ZO_001816"
     CDS             657..1283
                     /gene="ytpR"
                     /locus_tag="ACF4ZO_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtpR family tRNA-binding protein"
                     /protein_id="HFD5487323.1"
                     /translation="MIFAYNKEQVGDVLMVILQDTKDIKRQVERKGKVARVFAEESGK
                     TLAWNIFEASSLITIEGNGQIFLTDEDLARLNAELAKEGFSERLEPTVGPVFVVGQIV
                     EMVAHPDSDHLNICQVAIGEDQTVQIVAGAPNAALGLKTIVALPGAIMPNGSLIFPGK
                     LRGEESYGMMCSPRELALPNAPQKRGIIELDESAVVGEAFDPAKHWKG"
     gene            1435..1830
                     /locus_tag="ACF4ZO_001817"
     CDS             1435..1830
                     /locus_tag="ACF4ZO_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HFD5487324.1"
                     /translation="MYNKVIAIGRLVAKPELVKTATDKHVARLSLAVNRRFKNASGER
                     EADFISVVVWGKLAETLVSYASKGSLMSIDGELRTRKYDKDGQVHYVTEVLCQSFQLL
                     ESRAQRAMRENNVTNDLVDLVLEEDTLPF"
     gene            complement(2090..2731)
                     /locus_tag="ACF4ZO_001818"
     CDS             complement(2090..2731)
                     /locus_tag="ACF4ZO_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HFD5487325.1"
                     /translation="MLIVLAGTIGAGKSSLAAALGEHLGTDVFYEAVDNNPVLDLYYQ
                     DPKKYAFLLQIYFLNKRFKSIKEAYQADNNILDRSIFEDELFLKLNYKNGNVTKTELD
                     IYQELLANMLEELEGMPKKRPDLLIYIDVSFDKMLERIEKRGRSFEQVDGNPSLEQYY
                     HQVHGEYPTWYEDYKVSPKMKIDGNSLDFVQNPQDLATVLKMIDTKLKELHLL"
     gene            complement(2751..3728)
                     /gene="dusB"
                     /locus_tag="ACF4ZO_001819"
     CDS             complement(2751..3728)
                     /gene="dusB"
                     /locus_tag="ACF4ZO_001819"
                     /EC_number="1.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017150 - tRNA dihydrouridine synthase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HFD5487326.1"
                     /translation="MIKLNSSFRIGDVEIPHRTVLAPMAGVTNSVFRTIAKEFGAGLV
                     VMEMISEKGLLYNNEKTLHMLHIDENEHPMSIQLFGGDAEGLKRAADFIQTNTKADIV
                     DINMGCPVNKVVKNEAGAKWLRDPDKIYHIVKEVTSVLDIPLTVKMRTGWADSSLAVE
                     NALAAESAGVSALAMHGRTREQMYTGTCDHDTLARVSKAITKIPFIGNGDVRSVQDAK
                     FMIEEIGVDAVMIGRAAMNNPYLFTQINHFFETGQELPDLPFAKKLDIAKDHLKRLIN
                     LKGETIAVREFRGLAPHYLRGTAGAAKVRGAVSRAETLAEVEAIFETVR"
     gene            complement(3715..4587)
                     /gene="hslO"
                     /locus_tag="ACF4ZO_001820"
     CDS             complement(3715..4587)
                     /gene="hslO"
                     /locus_tag="ACF4ZO_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HFD5487327.1"
                     /translation="MDKIIKSIAQSGAFRAYVLDSTETVALAQEKHNTLSSSTVALGR
                     TLIANQILAANQKGDSKITVKVIGDSSFGHIISVADTKGHVKGYIQNTGVDIKKTATG
                     EVLVGPFMGNGHFVTIIDYGTGNPYTSTTPLITGEIGEDFAYYLTESEQTPSAIGLNV
                     LLDENDKVKVAGGFMVQVLPGASEEEIARYEKRLQEMPAISHLLASKNHVDALLEAIC
                     GDEPYKRLSEEPLSFQCDCSRERFEAALMTLPKADLQAMIDEDKGAEIVCQFCGTKYQ
                     FNESDLEAIINDKA"
     gene            complement(4734..6223)
                     /gene="rofA"
                     /locus_tag="ACF4ZO_001821"
                     /pseudo
     CDS             complement(4734..6223)
                     /gene="rofA"
                     /locus_tag="ACF4ZO_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_047149466.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator RofA"
BASE COUNT         2021 a         1127 c         1371 g         1935 t
ORIGIN      
        1 agatcgtcca atttgatctt tttatgataa aatgagggat atgagtaaaa agaaaatagg
       61 tatgatttca ggtatctttg gatttagttt agctattggc ctaggagtag ttatcaaaga
      121 ttattgccaa gacaggcagc gccgacaaat gacaagggat ttacgcacct ttttttcacc
      181 tttaggacaa atcgaagttt tatatatcaa tccttgccag gtcaaacaag attatatttc
      241 aggtggggtt gttatgtcaa acggcaaaca gtaccaattc acctatcaca gtcgacaaat
      301 tagttttgag gaggacaagg gatgatcaga ccgacttctt atgagtcatt agcggctctt
      361 attgaaaaag aagataagct ggtgttattt tttacggcag actggtgtcc agactgtcaa
      421 tttatttatc ctattatgcc agaaattgaa gcagaactta cagatatgac ttttgtttgt
      481 gttaatcgtg atcagtttat agaggtagca caaaagtggg atatttttgg tattcctagt
      541 tttgtcgtga ttgaaaaagg tcaggaagta gggcgtctgg ttaacaaaat gagaaagaca
      601 aaaactgaga ttatgcattt tttagctgct tatcaataag aaaagaggaa gaataaatga
      661 tttttgcata caataaagaa caagttggcg atgtcttgat ggttatctta caagacacca
      721 aagatatcaa acgtcaagta gaacgaaaag gcaaagtagc ccgtgttttt gcagaagaaa
      781 gcggcaaaac ccttgcttgg aatatctttg aagcgtcaag cttgattact attgaaggca
      841 atggacagat ttttttgaca gacgaggacc ttgcaagatt aaatgcagag cttgctaagg
      901 aaggattttc agaaaggctt gaaccgactg tgggacctgt ttttgtggtt ggtcaaattg
      961 ttgagatggt ggctcatcca gatagcgacc atcttaatat ctgtcaagtg gctattggtg
     1021 aagatcaaac ggttcaaatc gtagcgggcg caccaaatgc tgcgcttggt ttaaaaacga
     1081 ttgttgcctt accaggtgct ataatgccaa atggtagtct gattttccca ggaaaattgc
     1141 gtggtgaaga aagttatggt atgatgtgct ctcctcgtga gttagccttg ccaaatgcac
     1201 cgcaaaaacg tggcattatt gaacttgatg agtcagctgt ggtaggagaa gcttttgacc
     1261 cagccaaaca ttggaaaggt tagaaaaacc agctgaaata agtctgtatt taactaaatg
     1321 accagaaaaa aaggattagg agcccttaat ccttttttct tatgttttca aaaacgttta
     1381 aaatgaaact tattttacca caatttttac gaataataag ataaggaggt cagtatgtat
     1441 aataaagtga tagcaatcgg tcgtttggta gctaaaccag aattggtaaa aacagctacg
     1501 gataagcatg tagcacgtct ctctttagct gttaatcgaa gatttaaaaa tgcttctgga
     1561 gagcgagaag cggattttat ctctgttgtt gtttggggaa agttagctga aaccttggtt
     1621 tcttatgcta gcaaaggtag tttgatgtct attgatggcg aacttaggac ccgcaagtat
     1681 gataaagatg ggcaagtgca ttatgtgaca gaagttctct gccaatcatt tcaactgctt
     1741 gaaagtcgtg ctcagcgtgc tatgagagaa aataatgtta ctaatgatct agttgattta
     1801 gtcttagaag aagatactct tcccttttga taggggataa tgcttctcat cagggttcag
     1861 ctgattactg aaatagatga tgaggtgata cccgagcaac aaaagtgtga ccagatactt
     1921 ctgataaaaa taaaaaacca ccttacgagt atgaacaaag tttcaagtgc tagatgttgg
     1981 aactttgttc atcataggaa tagtagggtg ttttttagtg tattacttct ttttgttgct
     2041 agtgttaagg tttacttgct tacaaacggt tatcaggcca ctagagctct tataataaat
     2101 ggagctcttt gagtttggtg tcaatcattt ttaagacagt cgccaaatct tgtgggtttt
     2161 gaacgaagtc aagggaattg ccatcaattt tcatttttgg agagaccttg tagtcttcgt
     2221 accaggttgg gtattcaccg tggacttgat ggtaatattg ctcaagacta ggattgccgt
     2281 cgacctgctc aaaacttcgg ccacgttttt caatgcgctc aagcattttg tcaaaagaca
     2341 catcaatgta gatgagaaga tcagggcgtt ttttaggcat gccttctagt tcttctaaca
     2401 tgttggcgag aagttcctga tagatgtcaa gttctgtctt agtgacattg ccatttttgt
     2461 agttaagttt taaaaagagt tcgtcttcaa aaatagagcg gtcaagaatg ttgttatcgg
     2521 cttgataagc ttctttgatg gacttaaacc gtttattcaa aaaataaatt tgaagtaaaa
     2581 aggcgtactt tttaggatct tggtagtaga ggtctagcac ggggttatta tcaacagctt
     2641 cgtaaaaaac gtcagttcct aaatgctctc caagtgcagc agcaagcgag ctcttgccag
     2701 ccccaattgt tccagctagt acaatcaaca tgcgtctcct tctaatgtca ttagcgtact
     2761 gtttcgaaga tggcttcaac ctcagctaga gtctcagcgc gtgaaacagc accacgaact
     2821 ttggcagcac ctgctgttcc gcgaagatag tgtggcgcta agccccgaaa ttcccgaaca
     2881 gcaatggttt cacctttgag gttaatcagg cgtttgaggt ggtctttggc gatgtctaat
     2941 tttttggcaa aaggaagatc tggcaattct tgtccagtct caaaaaaatg attgatttga
     3001 gtgaaaaggt aaggattgtt catggctgcg cggccaatca tcacggcatc tacaccgatt
     3061 tcttcaatca taaatttggc gtcttgcacc gaacgcacgt ccccatttcc aataaaggga
     3121 atcttagtga tagccttaga aactcgggct aatgtgtcat ggtcgcaggt tcctgtatac
     3181 atttgttcac gggtacgacc gtgcatggca agagcagata cacctgccga ctcagccgcg
     3241 agggcatttt caacagcaag tgaactatcc gcccaacctg tacgcatttt gacagtcagt
     3301 ggaatatcta aaacagacgt gacttccttg acaatgtggt aaatcttatc agggtcacgg
     3361 agccacttgg caccagcctc gtttttgaca actttattaa cagggcagcc catattaata
     3421 tcaacaatat cggccttggt attggtttga atgaaatcag ctgcacgttt caacccttct
     3481 gcgtcaccac caaataattg aatggacata gggtgctcat tttcatcaat atggagcata
     3541 tggagggtct tttcattgtt gtaaagaagc cctttttcgg aaatcatttc cataaccacc
     3601 aaaccagcac caaattcttt ggcgatggta cgaaagacag aattggtcac accagccatg
     3661 ggagcaagga cagtgcggtg agggatttcc acatcaccaa tcctaaagga agaattaagc
     3721 tttatcattg atgatggcct ccaaatcact ttcattaaat tggtacttgg taccacaaaa
     3781 ttggcaaaca atttcagcac ccttatcttc gtcaatcatg gcctgtaaat ctgcttttgg
     3841 caaagtcatt agggctgctt caaaacgttc tctagaacag tcacactgaa aactcagagg
     3901 ttcttcagaa agacgcttgt aaggttcatc tccacagatg gcctccaaaa gggcatccac
     3961 atgatttttg gaagctagta ggtgagaaat ggcaggcatt tcttgcaggc gtttttcata
     4021 gcgagcaatc tcttcttcag aagcgcctgg tagcacctgc accataaagc caccagcaac
     4081 cttgacctta tcattttcat ctaaaagcac attaagtccg attgcagatg gtgtttgctc
     4141 tgattcggtt aagtagtagg caaaatcctc accaatttcc ccagtaataa gaggcgttgt
     4201 tgaggtataa gggttacctg tgccataatc aataatcgtc acaaaatgac cattccccat
     4261 aaaaggccca acaaggactt cacctgttgc ggtcttttta atatcgacac cagtattttg
     4321 aatgtaacct ttcacatgtc ctttggtatc tgccacagag ataatgtgtc caaaagaaga
     4381 atcaccaatc actttgacgg tgattttact atcgcctttt tgattagccg ccaaaatctg
     4441 gttggcgatc aaggtacggc caagcgcaac agtagacgat gacagcgtgt tgtgtttttc
     4501 ttgagctaat gcaaccgtct cagtgctatc aaggacataa gctctaaaag cccctgattg
     4561 tgctatcgat ttaattattt tatccataac ttagattata gcataaagtg taaaacttgt
     4621 attgacagga ttgcttgaaa aatcaataca gatagacagt aaaaaatccc agagaatgac
     4681 tcgggattaa gttaaggtgt ggtctaaagt cgcgcaatgt ggtgacatgg cgcttatgtt
     4741 aattgcttgg ttaaatcagc ttggaatttt tcctctttaa ctcgatacat caattcttgg
     4801 atagacagaa tcgattcatc aaaagatatt tcagcaacag caattccttt tgtaagttca
     4861 tggtgaacaa aaggaatcag ttgactgtga gtgatgacca aatctggctt taaatcagga
     4921 atttgataaa cattatcttg caatagataa taggaatgaa aatcaatgct tttatccgag
     4981 aaataccttg ggaaagaatc tgttaggaga tgagcattga taaaattact ggctacgaaa
     5041 acaacaacta aaggaggttg gatatttctt agaatttgct cgacatagtg gcaaaaaaga
     5101 tgaaaatgct tatgattcaa gtaacgctta ccaggaagtt tggccagcca ctcttcgaca
     5161 attaacttta aggacgtata gagtttttgg ttttatagta cggagaaacg aataagttgg
     5221 tctcaggaat aaaatgttgc agattaaaca agaatgattt tgaaaaaaac ataagagctt
     5281 ttactaaact aggcttttgc tcttttaggt taggtaaaag agtgatgata ggctttaaaa
     5341 gcaggcgaaa agtatcattt tcttcaaaaa gttgacaaca ttgtctgata tgctcaggtg
     5401 tccattgtaa gctcgcaaaa gaattattag cggtgatata aattaaatag aggtagtcca
     5461 aatctcctgc tgaaaagttt agttggcagt aagtttcgat aatatcacgg ctactttttt
     5521 tcaaagaatc gtagataaaa agttttttta attgttgaaa aattctggtt tggggaatag
     5581 ttaccgaaaa ttgatgccgc ttccacgata aagccaataa aatgtcatag aaagaaaacg
     5641 attccgataa ccaaggagag gttttaaggt gggtggaact atgggataaa aagctatgaa
     5701 tagtgttttt gtcttgctgc gtcaagtcat aaactttaat gccaaactta ctatatagca
     5761 gagcgatgag gtaacggatg cgatattcct caccgacaat cttgttctta gagagtttta
     5821 attcaaagtt tcttaataaa ggaatcaatg cttcgcgcat ccgataagct gaggagtttg
     5881 ataaaaaatg acttctcgca aaatccgtaa ggggacgaga gtgggaacca ttttttatta
     5941 aaaaggctag taattgtaag acattagatg atgcatagag ttggtaaaga taagtttctt
     6001 taaaaggatg tgtaaattgg caagatatca tccttttttg gatggtcata gacagactat
     6061 cagggaaaaa ggcattcagt tcctcacaat aatggtttag ttgtaaaaag gttaagccag
     6121 ttttttctgc tacctcagtt attggcaaat aagatgtctt aaaaaacaag acaactaact
     6181 gacattttga ttcgattgat gattccaagt atttttctat caaggaaagg gacctctctt
     6241 cctacactta gaaagccaaa taagtatttg ataagtgtat tctcctattt caattctatc
     6301 taagctaaaa atagaaatca agtctaatgg tttttggtga aaagtcgaaa ccttttgaaa
     6361 tagctttaaa gcaatatttt ctcaaaaaat cattttcaaa aataatttgg tgaaaaatat
     6421 aatcaaaaaa ttgtctttct tgacaataac gtgg
//
LOCUS       DAXMQE010000063         5561 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.063, whole genome shotgun sequence.
ACCESSION   DAXMQE010000063 DAXMQE010000000
VERSION     DAXMQE010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5561)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5561)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5561
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.063"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            <1..174
                     /locus_tag="ACF4ZO_001822"
     CDS             <1..174
                     /locus_tag="ACF4ZO_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_process: GO:0030541 - plasmid partitioning [Evidence
                     IEA];
                     GO_process: GO:0051290 - protein heterotetramerization
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HFD5487328.1"
                     /translation="LSLSIFPERCAIIEDLIGKGYTFRQLIVKKYRIVYHVLEDEVII
                     VAVVYGSRHMNNW"
     gene            313..465
                     /locus_tag="ACF4ZO_001823"
     CDS             313..465
                     /locus_tag="ACF4ZO_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001873553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5487329.1"
                     /translation="MSPSDSKLSADHQSLSSDEQMTTVVEQARLDEIATSVLSRHLDA
                     FKELTE"
     gene            570..953
                     /locus_tag="ACF4ZO_001824"
                     /pseudo
     CDS             570..953
                     /locus_tag="ACF4ZO_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017769756.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
     gene            1088..1396
                     /locus_tag="ACF4ZO_001825"
     CDS             1088..1396
                     /locus_tag="ACF4ZO_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5487330.1"
                     /translation="MTRLIFQQILSEYVKSLEVEADKVVIPGQNTPVFSWDRDGNLSI
                     DTPLLEVRGESLATQADFTTISLTPGPKGELWQTSVERLDIKVDKHISLTFKNGVRID
                     "
     gene            1534..2331
                     /locus_tag="ACF4ZO_001826"
     CDS             1534..2331
                     /locus_tag="ACF4ZO_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFD5487331.1"
                     /translation="MIKLIATDMDGTFLAEDGTYNQEQLAALLPKLAEKGILFAVSSG
                     RSLLAIDQLFEPFLDQIAVIAENGSVVQYRGEILFADMMTKEQYTEVAKKVLANPHYV
                     ETGMVFSGQKAAYILKGASEEYIQKTKHYYANVKVINGFEDMENDAIFKVSTNFTGHT
                     VLEGSDWLNQALPYATAVTTGFDSIDIILKEVNKGFGMEHLCQALGIKKAETIAFGDN
                     FNDYQMLEFAGRAIATENARPEIKVISDQVIGHCNDGAVLTYLKGLV"
     gene            2335..3159
                     /locus_tag="ACF4ZO_001827"
     CDS             2335..3159
                     /locus_tag="ACF4ZO_001827"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFD5487332.1"
                     /translation="MNIRILALDLDGTLYNTEKIVTDANKKALAAAREKGVKVVITTG
                     RPLKAIGNLLEELDLLDHDDYSITFNGGLVQRNTGEVLDKSSLSFDQICQIQQALEAV
                     GLPTDIISGGDVYSIPSKDGRHSQYHLANPLLTFIEVTSVAELPKDITYNKIVTVTDP
                     DFLDQQIIKLSPSLFEDFEAFKSRDIIFEIMPKGIDKAFGLNLLCQHLGLEARHVMAM
                     GDEANDFAMLEWAGLGVAMANGVSGAKAVADAVTTLTNDESGVAEAVKTFILEEES"
     gene            3159..4709
                     /gene="ftsY"
                     /locus_tag="ACF4ZO_001828"
     CDS             3159..4709
                     /gene="ftsY"
                     /locus_tag="ACF4ZO_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005047 - signal recognition particle
                     binding [Evidence IEA];
                     GO_process: GO:0006614 - SRP-dependent cotranslational
                     protein targeting to membrane [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HFD5487333.1"
                     /translation="MGLFDRLFGKKETPKVAEEKLEENLLTETTQKEELSEKANEQDK
                     IEAVQQEDVSSEGAGSVENGPEAASVNALVEEETGDNSNHPSEDTNEFAADKTDLKVS
                     ELSQSTASEPKDLVDQPVVEQFPTKQAQADASNDSANEEAVDTSKEQSSSQQVMEDYY
                     RRKAALEKSLQEKAAATVPVMPEEVPQENQASTSAEASQNKATHDTIPETDQEKYKRS
                     LKKTRTGFSARLNSFFANFRRVDEEFFEDLEEMLILSDVGVHVATTLTEELRYEAKLE
                     NAKKPDALKRVIVEKLVDIYEKDGRYNEAINYQDGLTVMLFVGVNGVGKTTSIGKLAY
                     RYKQEGKKVMLVAADTFRAGAVAQLVEWGRRVDVPVITGPEKADPASVVFDGMEKAVA
                     KGVDILLIDTAGRLQNKENLMAELEKMGRIIKRVLPDAPHETLLALDASTGQNALSQA
                     KEFSKITPLTGLILTKIDGTAKGGVVLAIRQELDIPVKFIGFGEKVDDIGEFHSEDFM
                     KGLLEGIL"
     gene            complement(4763..>5561)
                     /locus_tag="ACF4ZO_001829"
     CDS             complement(4763..>5561)
                     /locus_tag="ACF4ZO_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFD5487334.1"
                     /translation="DSPVSEKVPFDWLAFIALSISLTSALLAITSLENASVNLYYLGL
                     FILSFVLFLYKNLTAKQPFLDIRILKIPSLTFGLIPFFVFQLINLGINFLTPNFIVME
                     KIANSSQAGMVLLPGTLLGALLAPAFGKLYDQKGARLSLYLGNALFSLSLIIMTLQTR
                     HFMPLPFTLLYILFTFGRNMGFNNSLATAIRELPAEKNADATAIFQMMQQFAGALGTT
                     MASLIANSQPEFTSGVQSVYLLFTIFALLDFIFFFAMFYHLGKKGLA"
BASE COUNT         1782 a          991 c         1308 g         1480 t
ORIGIN      
        1 ttatcactat ccatttttcc tgaacgttgt gccatcattg aggatctgat tggaaaaggc
       61 tataccttca gacaactgat tgtcaaaaaa tatcgcattg tatatcatgt tctggaagat
      121 gaagttataa ttgttgcggt cgtctatgga tcacgtcata tgaataattg gtaaagtaag
      181 ggagagtgat gtatggaact cgtaaagacg atacaaattg gtgatgacat ctatcttccg
      241 atacctgacc catttggcat tcaagagaat taggagttta acctttataa atcaactgat
      301 ggaactttgg tattgagtcc atctgatagc aaactatcag cggatcacca aagtttaagc
      361 agtgatgagc agatgacaac agttgttgaa caagcaaggt tagatgagat tgcgacttca
      421 gtattatcac gacatcttga cgcatttaag gaattgacag aatgagaata ctaggttttg
      481 taagaaagac tgttgattac tttgaaagaa atataccgaa agcacttcaa aggaggtgct
      541 ttttttgtac cccaaaataa ggagggctta tgggactact tgatttaatt ggaagaaaaa
      601 gggctagaga taagcctcaa aacagttatg aaggtcagga ctttttctac ctctttggtc
      661 gcacgactag tggcgagaat gtggatgagt ttaaggctat gcagacgacg gcagtctatg
      721 cctgtgtgcg tattcttgct gaagcggtgg cgtcacttcc tattcacatc tatgaacgga
      781 cagaaaatgg gaaggagaaa aagctggacc acccactgta ctttcttctt catgatgaac
      841 ccaatccaga gatgtcctcc tttatctttc gagagacaat catgagccat cttttgatat
      901 ggggaaatgc ctatgtacag attatacgag ataaaagtgg tatggtatcg ctactgctaa
      961 agcagaaggc gagcgttctg ataagaaagc tgctcttgat tatctggcaa cggatgcctt
     1021 agaagcacga gttgcagcac ttcaaaaagc taagattgat gagttgaccg tctctagttc
     1081 agcatggatg acaaggctta tcttccaaca gattctatca gagtatgtga agagcctaga
     1141 agttgaagct gataaggtcg ttattccagg acagaatact ccagtcttta gttgggatag
     1201 ggatgggaat ctttccattg acacaccgct cctagaggtg agaggggaaa gtctagcgac
     1261 acaagctgac tttacaacca tctctttaac tcctggtcca aagggagaac tctggcagac
     1321 aagtgttgaa aggttggata taaaagtaga caagcacatc agcctaacct tcaaaaatgg
     1381 cgtacggatt gattgataaa aggcaagggc gtatcaattc ggcacgtcct tttttagttt
     1441 atctgtggta taatgaaaga agttatattg ggagttgaga tgcacgattc atttggattt
     1501 tgcactccct aaaaagggta aaggttagat tgtatgatta aactaatagc aacagatatg
     1561 gatggtacct tcctagctga agatggtact tataatcaag agcaactagc tgcgctcttg
     1621 ccaaagttag ccgaaaaagg cattttattt gcggtttcga gtggccgctc gctcttagcc
     1681 attgatcagc tctttgagcc ctttttggat cagattgctg ttattgcaga aaatggttcc
     1741 gtggttcaat accgtggtga gattctattt gcagatatga tgaccaaaga gcagtatacc
     1801 gaagttgcaa aaaaggtttt agccaatcct cactatgtag aaacaggtat ggttttttct
     1861 gggcaaaagg cagcctatat tttaaaaggc gcatcagaag agtacattca aaaaacaaaa
     1921 cattactatg ctaatgttaa ggttattaat ggttttgaag atatggagaa tgacgccatt
     1981 tttaaagttt ctaccaactt cacaggccat accgtcttag aaggaagcga ttggttgaat
     2041 caagccctcc cttatgccac tgcagtgacc accggctttg attccattga tattatctta
     2101 aaagaggtga ataagggctt tggtatggag catctttgtc aagccttggg cattaagaaa
     2161 gcagaaacga ttgcttttgg ggataatttt aatgattacc agatgttgga gtttgctggt
     2221 agggctattg ctacggaaaa tgcaagacct gaaatcaaag tgatttcaga ccaagtcatt
     2281 ggtcactgta atgacggagc agtactaacg tatttaaaag gactagtgta actcatgaat
     2341 attagaattt tggcgcttga tttagacgga accctctaca acactgaaaa aattgtcaca
     2401 gatgccaata aaaaagcctt agcagcggct agagaaaaag gggttaaggt ggttattacc
     2461 acaggtcgcc ctctaaaggc catcggtaac ttgctagaag agttggactt gcttgaccac
     2521 gatgactaca gtattacctt taatgggggt ttggttcagc gaaatacagg ggaggttttg
     2581 gataagagtt ctctcagttt tgaccagatt tgccagattc agcaagcttt agaggcggtt
     2641 ggcttaccaa cagatattat cagtggtggg gatgtgtata gcattccaag taaggacggt
     2701 aggcattcgc agtaccatct agctaaccca ctgttgacct ttattgaggt gacatctgta
     2761 gcggaactac caaaagacat tacctataac aaaattgtga cagtcaccga tccagacttt
     2821 ttggatcagc agattataaa gctatcccca agcttatttg aggattttga agcctttaaa
     2881 tcacgagata ttatttttga aatcatgcca aaaggcattg ataaagcttt tggattaaac
     2941 ttgctttgcc agcaccttgg ccttgaagct agacatgtca tggctatggg agacgaagct
     3001 aacgactttg cgatgttaga atgggcagga cttggagtag ctatggctaa tggtgtttca
     3061 ggagctaaag ccgttgccga tgccgtgacc accttgacca atgatgagtc tggagttgca
     3121 gaagctgtga agacatttat tttagaagag gagagttaat gggattattt gatcgtttat
     3181 ttgggaaaaa agaaaccccg aaggtagctg aggaaaagtt agaagaaaat cttttgacag
     3241 aaacaactca gaaagaggag ctttctgaaa aagccaatga gcaagacaag attgaggcgg
     3301 ttcaacaaga ggacgtttct tcagagggcg caggttcggt ggaaaatggt cccgaagcag
     3361 cttcagtaaa cgcactggtt gaggaagaaa caggtgacaa tagtaatcat ccatcagaag
     3421 ataccaatga gtttgctgcc gacaaaacag accttaaggt aagtgaactt agtcaatcta
     3481 cggcatcaga accaaaagac cttgttgacc agccagttgt ggaacagttt ccaacaaaac
     3541 aagcccaagc tgatgcctca aatgattcgg cgaatgaaga agcagtagac acttcaaaag
     3601 agcaatccag tagccaacag gttatggaag actactaccg tcgtaaggct gctcttgaaa
     3661 aaagccttca agaaaaagca gcggcaacgg ttccagtgat gccagaagaa gttccacaag
     3721 aaaatcaggc ctctacctca gcagaagctt ctcaaaacaa ggcaacccac gataccattc
     3781 ctgagacaga tcaagaaaaa tacaagcgta gcttgaaaaa aacgcggact ggcttctcag
     3841 ctcgtctgaa cagtttcttt gccaatttca ggcgagtgga tgaagaattc tttgaagact
     3901 tggaagaaat gctgatctta tcagatgtcg gtgtacatgt ggcgacaact ctgacagagg
     3961 agttgcgtta tgaagccaaa ctggaaaatg cgaaaaaacc agatgccttg aaacgtgtga
     4021 ttgtggaaaa attggtagat atctatgaaa aagatgggcg ttataatgaa gccattaatt
     4081 atcaagatgg cttgacggtt atgctttttg taggtgttaa cggggttggt aaaacgactt
     4141 caatcgggaa gctggcttac cgttacaaac aagaaggtaa aaaagtcatg ttggtggcag
     4201 cagatacctt ccgagcaggg gctgtggctc agctagtcga atggggacgc cgagtagatg
     4261 tgccagtcat tactggccct gaaaaggctg atccagcgtc tgttgttttt gacgggatgg
     4321 aaaaagctgt ggcaaaaggt gtagatattc tcctgattga cacggctggt cgcctgcaaa
     4381 acaaagaaaa tctcatggca gagctggaaa aaatgggtcg tatcattaag cgtgtgctac
     4441 cagatgcccc tcatgaaacg cttttggcct tagatgcgtc aacaggtcaa aatgcgctta
     4501 gccaagccaa ggaattttca aaaataacgc cattgacagg tttgatttta acgaaaattg
     4561 atgggactgc caaaggtggt gtagtcctag ccatccgtca agaattagac attccagtca
     4621 agttcatcgg atttggtgaa aaagtggatg atattggaga attccactca gaagacttta
     4681 tgaaaggcct tttggaaggt atcttataac agcaaaaacc agtctcgttc aataaaacga
     4741 gactggtttt tagtatgtca tcttaggcta gtcctttttt ccctaaatgg taaaacatag
     4801 caaagaaaaa gataaaatca agtagagcaa aaatagtaaa gagaaggtag acagattgga
     4861 caccacttgt gaattctggt tgactatttg ctatcagtga tgccatagta gttcctagag
     4921 cgccagcaaa ttgctgcatc atctgaaaaa tggccgtggc atcggcattt ttctcggcag
     4981 gcaattctcg aatagccgtg gctaagctat tattaaagcc catgttacgc ccaaacgtga
     5041 ataaaatata taaaagagtg aatggtaaag gcataaaatg tcttgtttga agtgtcataa
     5101 taatcaatga taaactaaat aaggcatttc ctaaataaag cgaaagtctt gctccttttt
     5161 gatcataaag tttaccaaaa gcaggtgcta gtagagctcc gagtaaggta ccaggtagta
     5221 acaccatacc agcttgagaa ctattagcaa tcttttccat gacaataaag tttggcgtta
     5281 gaaaatttat gcctaaatta atcagctgga agacaaaaaa gggaatcagg ccaaaggtta
     5341 gagagggaat tttgagaatg cgaatatcaa gaaagggttg cttagctgtg agattcttgt
     5401 agaggaagag gacaaagctg agaataaaaa gccctaagta atacaaatta acacttgcgt
     5461 tttctagact agtaatagct aataaggcag aagttaagct aatcgatagt gcaataaatg
     5521 ccaaccagtc aaagggtact ttttcgctta ctggagaatc t
//
LOCUS       DAXMQE010000064         5154 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.064, whole genome shotgun sequence.
ACCESSION   DAXMQE010000064 DAXMQE010000000
VERSION     DAXMQE010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5154)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5154)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5154
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.064"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            101..1649
                     /locus_tag="ACF4ZO_001830"
     rRNA            101..1649
                     /locus_tag="ACF4ZO_001830"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            1701..1773
                     /locus_tag="ACF4ZO_001831"
     tRNA            1701..1773
                     /locus_tag="ACF4ZO_001831"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1734..1736,aa:Ala,seq:tgc)
     gene            2072..4974
                     /locus_tag="ACF4ZO_001832"
     rRNA            2072..4974
                     /locus_tag="ACF4ZO_001832"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            5060..>5154
                     /gene="rrf"
                     /locus_tag="ACF4ZO_001833"
     rRNA            5060..>5154
                     /gene="rrf"
                     /locus_tag="ACF4ZO_001833"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         1462 a         1060 c         1480 g         1152 t
ORIGIN      
        1 agacgaacca aacgtgaggg tgatatggag acatattacc cgtcaagaaa cgagaaataa
       61 atctgtcagc gacagaagga acgagtaagt tcaaacgcaa attaaagaga gtttgatcct
      121 ggctcaggac gaacgctggc ggcgtgccta atacatgcaa gtagaacgct gagaactggt
      181 gcttgcaccg gttcaaggag ttgcgaacgg gtgagtaacg cgtaggtaac ctacctcata
      241 gcgggggata actattggaa acgatagcta ataccgcata agagagacta acgcatgtta
      301 gtaatttaaa aggggcaatt gctccactat gagatggacc tgcgttgtat tagctagttg
      361 gtgaggtaaa ggctcaccaa ggcgacgata catagccgac ctgagagggt gatcggccac
      421 actgggactg agacacggcc cagactccta cgggaggcag cagtagggaa tcttcggcaa
      481 tgggggcaac cctgaccgag caacgccgcg tgagtgaaga aggttttcgg atcgtaaagc
      541 tctgttgtta gagaagaatg atggtgggag tggaaaatcc accaagtgac ggtaactaac
      601 cagaaaggga cggctaacta cgtgccagca gccgcggtaa tacgtaggtc ccgagcgttg
      661 tccggattta ttgggcgtaa agcgagcgca ggcggttttt taagtctgaa gttaaaggca
      721 ttggctcaac caatgtacgc tttggaaact ggagaacttg agtgcagaag gggagagtgg
      781 aattccatgt gtagcggtga aatgcgtaga tatatggagg aacaccggtg gcgaaagcgg
      841 ctctctggtc tgtaactgac gctgaggctc gaaagcgtgg ggagcaaaca ggattagata
      901 ccctggtagt ccacgccgta aacgatgagt gctaggtgtt aggccctttc cggggcttag
      961 tgccggagct aacgcattaa gcactccgcc tggggagtac gaccgcaagg ttgaaactca
     1021 aaggaattga cgggggcccg cacaagcggt ggagcatgtg gtttaattcg aagcaacgcg
     1081 aagaacctta ccaggtcttg acatcccgat gcccgctcta gagatagagt tttacttcgg
     1141 tacatcggtg acaggtggtg catggttgtc gtcagctcgt gtcgtgagat gttgggttaa
     1201 gtcccgcaac gagcgcaacc cctattgtta gttgccatca ttaagttggg cactctagcg
     1261 agactgccgg taataaaccg gaggaaggtg gggatgacgt caaatcatca tgccccttat
     1321 gacctgggct acacacgtgc tacaatggtt ggtacaacga gtcgcaagtc ggtgacggca
     1381 agctaatctc ttaaagccaa tctcagttcg gattgtaggc tgcaactcgc ctacatgaag
     1441 tcggaatcgc tagtaatcgc ggatcagcac gccgcggtga atacgttccc gggccttgta
     1501 cacaccgccc gtcacaccac gagagtttgt aacacccgaa gtcggtgagg taacctatta
     1561 ggagccagcc gcctaaggtg ggatagatga ttggggtgaa gtcgtaacaa ggtagccgta
     1621 tcggaaggtg cggctggatc acctcctttc taaggaaatg gaacacgttt atcgtcttat
     1681 ttagttttga gaggtcttgt ggggccttag ctcagctggg agagcgcctg ctttgcacgc
     1741 aggaggtcag cggttcgatc ccgctaggct ccatcaggat acaatcctac taaacttaat
     1801 acaagtgaag ttgaacacgc cactaacttc ctaggaaaat agacaatctt cgcttgtctg
     1861 caaggcacac atggtcagat tcctaatttt ctacagaagt ttcgctaaag cgagcgttgc
     1921 ttagtatcct atataatagt ccattgaaaa ttgaatatct atatcaaatt ccacgatcta
     1981 gaaatagatt gtagaaaagt aacaagaaaa taaaccgaaa acgctgtgat tatttaataa
     2041 gttttctagt ttaaaaaaac taggttaata aggttaagtt aataagggcg cacggtggat
     2101 gccttggcac tagaagccga agaaggacgt gacaaacgac gaaatgcttt ggggagctgt
     2161 aagtaagcgc tgatccagag atgtccgaat gggggaaccc actaactaat ggttagtatc
     2221 cataactgtt aaggttatga gaaggaagac gcagtgaact gaaacatcta agtagctgca
     2281 ggaagagaaa gcaaacgcga ttgccttagt agcggcgagc gaaacggcag gagggcaaac
     2341 cgaagtgttt acacttcggg gttgtaggac tgcgacgtgg gactttaaaa ggatagaaga
     2401 attacctggg aaggtaagcc aaagagagta aaagcctcgt atttaaaatt cttttgagcc
     2461 ctagcagtat cctgagtacg gcgagacacg tgaaatctcg ttggaatctg ggaggaccat
     2521 ctcccaaccc taaatactct ctagtgaccg atagtgaacc agtaccgtga gggaaaggtg
     2581 aaaagcaccc cgggagggga gtgaaataga acctgaaacc gtgtgcctac aacaagttcg
     2641 agcccgttaa tgggtgagag cgtgcctttt gtagaatgaa ccggcgagtt acgatatgat
     2701 gcgaggttaa gttgaagaga cggagccgta gggaaaccga gtcttaatag ggcgatttag
     2761 tatcatgttg tagacccgaa accatgtgac ctacccatga gcaggttgaa ggtgaggtaa
     2821 aactcactgg aggaccgaac cagggcacgt tgaaaagtgc ttggatgact tgtgggtagc
     2881 ggagaaattc caaacgaact tggagatagc tggttctctc cgaaatagct ttagggctag
     2941 cgtcgatgtt aagtctcttg gaggtagagc actgtttggg tgaggggtcc atctcggatt
     3001 accaatctca gataaactcc gaatgccaac gagatatcat cggcagtcag actgcgagtg
     3061 ctaagatccg tagtcgaaag ggaaacagcc cagaccacca gctaaggtcc caaaataact
     3121 gttaagtgga aaaggatgtg gggttgcaca gacaactagg atgttagctt agaagcagct
     3181 attcattcaa agagtgcgta atagctcact agtcgagtga ccctgcgccg aaaatgtacc
     3241 ggggctaaaa cagtttaccg aagctgtgga tgacacaaaa gtgtcatggt aggagagcgt
     3301 tctatgtgtg aagaaggtgt accgtgagga gcgctggaac gcatagaagt gagaatgccg
     3361 gtatgagtag cgcaagacag gtgagaatcc tgtccaccgt aagactaagg tttccagggg
     3421 aaggctcgtc cgccctgggt tagtcgggac ctaaggagag accgaaaggt gtatccgatg
     3481 gccaacaggt tgatattcct gtactagagt atatagtgat ggagggacgc agtaggctaa
     3541 ctaaaccgga cgattggaag agtccggcta agcagtgagg tgtaagatga gtcaaatgct
     3601 tatctttata acattgagct gtgatgggga gcgaatttta gtagcgaagt tagtgatgtc
     3661 acactgccaa gaaaagcttc tagcgtttaa tgatactcta cccgtaccgc aaaccgacac
     3721 aggtagtcga ggcgagtagc ctcaggtgat cgagagaact ctcgttaagg aactcggcaa
     3781 aatgaccccg taacttcggg agaaggggtg ctgacttagg tcagccgcag tgaataggcc
     3841 caagcaactg tttatcaaaa acacagctct ctgctaaatc gtaagatgat gtataggggg
     3901 tgacgcctgc ccggtgctgg aaggttaaga ggagggttta gcgcaagcga agatctgaat
     3961 tgaagcccca gtaaacggcg gccgtaacta taacggtcct aaggtagcga aattccttgt
     4021 cgggtaagtt ccgacccgca cgaaaggcgt aatgatttgg gcactgtctc aacgagagac
     4081 tcggtgaaat tttagtacct gtgaagatgc aggttacccg cgacaggacg gaaagacccc
     4141 atggagcttt actgcagttt gatattgagt atctgtacca catgtacagg ataggtagga
     4201 gccattgact tcgggacgcc agtttcgaat gaggcgttgt tgggatacta cccttgtgtt
     4261 atggctactc taacccagat aggttatccc tatcggagac agtgtctgac gggcagtttg
     4321 actggggcgg tcgcctccta aagagtaacg gaggcgccca aaggttccct cagattggtt
     4381 ggaaatcaat cgcagagtgt aaaggtataa gggagcttga ctgcgagagc tacaactcga
     4441 gcagggacga aagtcgggct tagtgatccg gtggtaccga atggaagggc catcgctcaa
     4501 cggataaaag ctaccctggg gataacaggc ttatctcccc caagagttca catcgacggg
     4561 gaggtttggc acctcgatgt cggctcgtcg catcctgggg ctgtagtcgg tcccaagggt
     4621 tgggctgttc gcccattaaa gcggcacgcg agctgggttc agaacgtcgt gagacagttc
     4681 ggtccctatc cgtcgcgggc gtaggaaatt tgagaggatc tgctcctagt acgagaggac
     4741 cagagtggac ttaccgctgg tgtaccagtt gtcttgccaa aggcatcgct gggtagctat
     4801 gtagggaagg gataagcgct gaaagcatct aagtgcgaag cccccctcaa gatgagattt
     4861 cccatgattt tatatcagta agagccctga gagatgatca ggtagatagg ttaggagtgt
     4921 aagtgtagcg atacatgtag cggactaata ctaatagctc gaggacttat ccaaaaagaa
     4981 atattgacaa cgttacggat tcttgttaga ctatagatat tcaattttga gtgggttatg
     5041 agaatagcac atttacaagt taagtgacga tagcctagga gatacacctg tacccatgcc
     5101 gaacacagca gttaagccct agaacgcctg atgtagttgg gggttgcccc ctgt
//
LOCUS       DAXMQE010000065         4556 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.065, whole genome shotgun sequence.
ACCESSION   DAXMQE010000065 DAXMQE010000000
VERSION     DAXMQE010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4556)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4556)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4556
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.065"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            105..647
                     /locus_tag="ACF4ZO_001834"
     CDS             105..647
                     /locus_tag="ACF4ZO_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family protein"
                     /protein_id="HFD5487335.1"
                     /translation="MDIWTKLAVFAFFETPKVILRPFRYEDHWDFYSMVNDTKNLYYV
                     FPEQKTKAASDYLLVHSFIKFPLGQWAIEDKATHQVIGSIRIEHYDAKTRCADIGYFL
                     NYAFWGQGIMTEVVIKLVYLSFHEFGLKTLRIITHLENKASQKVAKKAGFQLKTCFKG
                     SDRNTHKICIYKMYQLTNDR"
     gene            656..1939
                     /gene="spxR"
                     /locus_tag="ACF4ZO_001835"
     CDS             656..1939
                     /gene="spxR"
                     /locus_tag="ACF4ZO_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS-HotDog domain-containing transcription
                     factor SpxR"
                     /protein_id="HFD5487336.1"
                     /translation="MSKHQDILDYLEKLAIGKKVSVRSISNHLKVSDGTAYRAIKEAE
                     NRGIVETKPRSGTVRIEKKGRVRIDRLTYSEIARISDSEVLAGHAGLGHEFSRFSIGA
                     MTQQNIRRYLVKGGLLIVGDRETIQLLALENHNAILVTGGFPVSKRVIEMANNQRIPV
                     MVTHYDTFTVATMINHALSNIRIKTDLKTVEQVMIPITDYGYLCENSSVEEFNTLIKK
                     TRQVRFPVLDYKRKVIGVVSMRDVVDQLPTTKLTKVMSKNPITARPNTSLANISQKMI
                     FEDLNMLPVTDEENNLLGMITRRQAMENLPNHQPNNPYTYSEQILSNLEETVDYYQVV
                     VEPTMIDSAGNMSNGVISEFLKEISIRALTKKHQKNIIIEQMMVYFLHAIQIEDELKI
                     YPKIITENRRSSTIDIEIFVDDQVIAKAIITTKIN"
     gene            1955..2815
                     /locus_tag="ACF4ZO_001836"
     CDS             1955..2815
                     /locus_tag="ACF4ZO_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HFD5487337.1"
                     /translation="MITLKSAREIEAMDRAGDFLAGIHIGLRDIIKPGVDMWEVEAYV
                     RRRCKEDNVLPLQIGVDGHMMDYPYATCCGLNDEVAHAFPRHYILKEGDLLKVDMVLS
                     EPLDKSIVDVAALDFDNVPEMKKWTGSYTGGLADSCWAYAVGTPSDEIKQLMDVTKEA
                     MYRGIEKAVIGNRIGDIGAAVQEYAESFGYGVVRDLVGHGVGPTMHEEPMVPNYGTAG
                     HGLRLKEGMVLTVEPMINTGTWEIDTDIKTGWAHKTLDGGLSCQYEHQFVITKDGPVI
                     LTSQGEERTY"
     gene            2817..3782
                     /locus_tag="ACF4ZO_001837"
     CDS             2817..3782
                     /locus_tag="ACF4ZO_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HFD5487338.1"
                     /translation="MAEKKWFDKVLSKWQYEPIQVFMRHLQSAEMDLSAIAVAYYLIL
                     TAFPLIVIAANIFPYLNIDIADLLRLMKQNLPKDIFRPASAIVENIFSKPSGSVLGVA
                     TLTGLWTMSRSLTSLQKAINKAYGASQHRDFFIGHLVGLLTSLIILFLLAFALIFSTF
                     SKAAIQVLDKHYHLSDNITTIFLLLIQPITVLIIFVGLMLLYFLLPNVKIKKIRYILP
                     GTLFTSFVMTFLSNLVGNYVVYNVERMVDIKMFGSVMIFIIMLWFIFLARILILGAIF
                     NATYQEMSLGKLEGRSGDMIAILKKTLGNDSDLSPSQSIEDSHTD"
     gene            3893..>4556
                     /locus_tag="ACF4ZO_001838"
     CDS             3893..>4556
                     /locus_tag="ACF4ZO_001838"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003866 - 3-phosphoshikimate
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HFD5487339.1"
                     /translation="MKLRTNAGPLQGTIQVPGDKSISHRAVILGAVAKGETRVKGLLK
                     GEDVLSTIQAFRNLGVRIEEKDDQLVIEGQGFQGLTAPCQTLNMGNSGTSMRLIAGLL
                     AGQPFSVKMIGDESLSKRPMDRIVYPLKQMGVEISGETDRQFPPLQLQGNRNLQPITY
                     TLPISSAQVKSAILLAALQAKGTTQVVEKEITRNHTEEMIQQFGGRLIVDGKRITLVG
                     PQQ"
BASE COUNT         1484 a          735 c          943 g         1394 t
ORIGIN      
        1 taacccagtt gtatcaaagg atagataaag actaagactg ttatagaata tttgcaaaag
       61 atttgttata atggacccaa tacaggtatt gtgaaaggta taatatggat atttggacaa
      121 agcttgcagt gtttgctttt tttgagactc cgaaagtaat attacggcct tttcgctatg
      181 aagatcattg ggatttttac agcatggtta acgacactaa aaacctttat tatgtttttc
      241 cagaacaaaa aactaaggca gcaagtgact atcttttagt acatagtttt ataaagtttc
      301 ctttaggtca gtgggcaata gaagataaag caacccacca agtaataggt tctattagaa
      361 ttgagcatta tgatgctaaa acgcgttgtg ctgatattgg ctatttttta aactatgcct
      421 tttggggaca aggaattatg acagaagtcg taataaaact tgtttattta tcttttcacg
      481 aatttggtct caaaacgttg cgtattataa ctcatttaga aaataaggcc agccagaaag
      541 tagctaaaaa agcaggtttt caactaaaaa cctgttttaa aggaagtgat cgtaatactc
      601 ataaaatctg catttataaa atgtaccaac taactaatga taggtgataa tcattatgag
      661 caaacatcaa gatattttag attatttaga aaaacttgct attggtaaaa aagtgagtgt
      721 tagaagcatt tcaaaccact taaaagtaag cgatggaaca gcctaccgtg ctattaaaga
      781 ggcagaaaat cgaggtattg tcgaaaccaa accaagaagt ggaactgttc gtattgaaaa
      841 aaaaggacgg gttcgtattg accgtctgac ctattccgaa attgctcgga tcagtgattc
      901 ggaagtgcta gcgggacatg ctggtttagg acatgaattc agtaggtttt caattggtgc
      961 tatgactcaa caaaatattc gtcgttactt ggtcaaagga gggttattaa tagttgggga
     1021 tcgtgaaacg attcaactct tagctcttga aaaccataat gccattttgg tgacgggcgg
     1081 atttccagta tccaaacgtg ttattgaaat ggcaaataac caacgaatcc cagttatggt
     1141 aactcattat gataccttta ctgtggcaac aatgattaat cacgcgctat ctaatattcg
     1201 tattaaaaca gatctcaaaa cagttgaaca ggtaatgata cctattacag attatggtta
     1261 cctttgcgaa aacagctctg ttgaagaatt caatacatta ataaaaaaaa cacgacaagt
     1321 caggtttcct gtattagatt ataaaagaaa agtgattggt gtagttagta tgcgtgatgt
     1381 ggtggatcag ttgccaacaa ctaagcttac caaggttatg tctaaaaatc caataacggc
     1441 tagaccaaat actagtcttg ctaatattag ccagaaaatg atctttgaag atttaaacat
     1501 gttacctgtc actgacgaag aaaacaattt acttggtatg attactcgta gacaagcaat
     1561 ggaaaatttg ccaaatcacc aacccaataa cccctatact tatagtgagc aaatactttc
     1621 taaccttgaa gaaacggttg attattacca agtagtagtt gagccaacaa tgattgatag
     1681 tgctggtaac atgtcaaacg gtgttatttc agagttctta aaggaaatta gtatcagagc
     1741 cctcacgaaa aagcaccaaa aaaatatcat tatcgaacaa atgatggtat actttttaca
     1801 tgctattcaa attgaggatg aattaaaaat atatcctaaa atcattactg aaaataggcg
     1861 aagcagcacc attgatattg aaatttttgt ggatgatcaa gtgattgcta aagctattat
     1921 tacaacgaaa ataaattaga ggagtaacaa aacaatgata acattaaaat cagcccgtga
     1981 aatagaagcg atggatagag caggagactt cttagcaggt atccatattg gcttaaggga
     2041 tattattaag cctggtgtgg atatgtggga agtggaagca tatgttcgtc gccgttgtaa
     2101 agaagacaac gttcttcctt tgcaaatagg ggttgatggt cacatgatgg actatcctta
     2161 tgcgacctgt tgtggtctaa atgacgaagt agcacatgcc tttccccgtc attacattct
     2221 gaaagaaggg gatttgctta aagttgacat ggtactcagt gagcctttgg ataaatcaat
     2281 tgttgatgta gcagctttag attttgataa cgtgcctgag atgaagaaat ggacaggatc
     2341 ttatactggt ggtttagctg actcttgttg ggcttatgct gttggaacac cgtctgacga
     2401 aataaagcag ttaatggatg tcaccaaaga agccatgtac cgtggtattg aaaaagcagt
     2461 aattggcaat cgtattggtg atattggcgc agctgttcaa gaatacgctg aaagcttcgg
     2521 ttatggtgtc gtgcgtgatc ttgttggtca cggtgttggt cctacaatgc atgaagagcc
     2581 aatggtacca aactatggaa cagcaggtca tggacttcgt ctaaaagaag gcatggtctt
     2641 gactgttgag ccaatgatta atacaggaac ttgggaaatt gataccgaca tcaagacagg
     2701 ttgggctcat aaaaccctgg atggtggttt atcttgccaa tacgaacacc aatttgtgat
     2761 tactaaagat ggtcccgtta ttttaacaag tcaaggagaa gaaagaactt actaaaatgg
     2821 cagaaaaaaa atggtttgat aaggtacttt ccaagtggca gtatgaacca attcaagtct
     2881 ttatgaggca tttacaaagt gcagaaatgg atttatctgc cattgcggtt gcgtattacc
     2941 ttatcttaac ggcctttcca ttaattgtta ttgcagccaa tatttttcct tacctcaata
     3001 ttgatattgc tgatttgtta cgtttaatga agcaaaattt gcctaaagat atttttagac
     3061 cggcttctgc aattgtagaa aatattttct ctaaaccgtc tggaagtgtt ttgggagtag
     3121 cgactttgac aggattatgg acaatgtctc gaagtttgac atcgctgcaa aaagctatta
     3181 ataaagccta tggcgcttct cagcatcgag atttctttat cggacacttg gttggtttgt
     3241 tgaccagttt aattatttta tttttattag cctttgcctt aatcttttca acattttcta
     3301 aagctgctat tcaagtgctg gataagcatt accatttgag tgataatatc acaacgattt
     3361 tcttactcct cattcaacct attacagttt tgattatttt tgttggcttg atgctactat
     3421 attttttatt acccaatgtt aagattaaaa aaattcgcta cattttacca ggaaccctat
     3481 ttacatcttt tgtgatgaca tttttgagta atctggttgg caattacgtt gtgtataatg
     3541 ttgagcggat ggtagatatt aaaatgtttg gttcagttat gatttttatc atcatgctat
     3601 ggtttatttt cttagcaaga atcctgattt taggagctat atttaatgcg acctatcaag
     3661 aaatgtcctt ggggaaatta gaaggtcgta gtggtgatat gatcgctatc cttaaaaaaa
     3721 cacttgggaa tgattcagat ctatctcctt cacagtctat cgaagatagt cacactgatt
     3781 gatacaaaaa agataataag tcgtggagtg agaaactatt ttcttgcttc attttttatg
     3841 aggatgaata gaaaatcatt gatcttagca aatagaaagg cagatgaaac ggatgaaatt
     3901 gcgaacaaat gcaggaccgt tacagggaac gattcaagtt ccaggagaca agtccattag
     3961 tcaccgggca gtcatattag gagccgttgc taaaggggaa acacgagtaa aaggactctt
     4021 aaaaggagaa gatgtgcttt ccacgattca agcctttagg aatttggggg tccgtatcga
     4081 agaaaaagat gaccagcttg tgatagaagg tcaaggtttt caaggattga ccgctccttg
     4141 tcagacactt aatatgggaa attctggaac ctctatgcgc ctcattgctg gtttattggc
     4201 aggtcaacct tttagtgtca aaatgattgg cgatgaaagc ttatccaaac gtcctatgga
     4261 tcggattgtt tatccgttaa agcaaatggg ggttgagata tctggagaaa cagataggca
     4321 atttcctcca ctacaattgc aaggtaatcg taatttacaa ccaatcacgt atactttgcc
     4381 tatctcttct gctcaggtta agtcagctat tttgttagca gctttgcaag caaaaggaac
     4441 aacacaggtt gttgaaaaag agattactcg aaaccataca gaagaaatga ttcaacaatt
     4501 tggtggacga ttgatagttg atggtaaacg cattactttg gtgggacccc agcagc
//
LOCUS       DAXMQE010000066         4524 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.066, whole genome shotgun sequence.
ACCESSION   DAXMQE010000066 DAXMQE010000000
VERSION     DAXMQE010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4524)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4524)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4524
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.066"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            complement(<1..345)
                     /locus_tag="ACF4ZO_001839"
     CDS             complement(<1..345)
                     /locus_tag="ACF4ZO_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000823056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosyltransferase family protein"
                     /protein_id="HFD5487340.1"
                     /translation="MKTKEIVDDVTMKRAITRITYEIIERNKQLDNVVLAGIKTRGVF
                     LARRIQERLHQLEGLDLPIGELDTKPFRDDMRVEEDTTLMSVDITGKDVILIDDVLYT
                     GRTIRAAIDNLVS"
     gene            complement(741..1631)
                     /locus_tag="ACF4ZO_001840"
     CDS             complement(741..1631)
                     /locus_tag="ACF4ZO_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HFD5487341.1"
                     /translation="MEINVITSGQRLDKALADLSPLSRGQANDQIKQGLVLVNGQQKK
                     AKYTVQAGDVICFELPKEEVLEYQAQNIPLDIIYEDDALAIINKPQGMVVHPSAGHPS
                     GTMVNALMYHIKDLSSINGVVRPGIVHRIDKDTSGLLMVAKTDAAHQALAEELKAKKS
                     LRKYLAIVHGNLPNDRGMIEAPIGRSEKDRKKQAVTAKGKEAVTRFTVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIGHPVAGDPLYGPRKTLSGHGQFLHAKTLGLTHPMTGKEM
                     IFTVEAPEIFQKVLKLLRKK"
     gene            complement(1621..2079)
                     /gene="lspA"
                     /locus_tag="ACF4ZO_001841"
     CDS             complement(1621..2079)
                     /gene="lspA"
                     /locus_tag="ACF4ZO_001841"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HFD5487342.1"
                     /translation="MKKRLFVLSLILLVALDQLSKFWIVSHIALGEVKPFIPGIVSLT
                     YLQNNGAAFSILQDQQWFFVAITVLVIGYAIYYLATHPHLNIWKQLALLLIISGGIGN
                     FIDRLRLAYVIDMVHLDFVDFAIFNVADSYLTVGVILLVICLWKEEDYGD"
     gene            complement(2076..2990)
                     /locus_tag="ACF4ZO_001842"
     CDS             complement(2076..2990)
                     /locus_tag="ACF4ZO_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFD5487343.1"
                     /translation="MNIQQLRYVVAIANNGTFREAASKLFVSQPSLSVSIKDLEAELG
                     FQIFNRTTSGTVLTSQGLVFYEKALEVVKSFDSFEKTFSQADLDQNEFSIASQHYDFL
                     PPLITAFSQQYDGHRVFRIFESTTIQILDEVAQGNSEIGIIYLNVDNQKGLFQRMDKL
                     GLEYVSLIPFTTHIYLSKTHPLANHEALYLNDIQGLPAVRFTQERDEYLYYSENFVDT
                     SECPRIYNVSDRATLNGILERTNAFATGSGFLDHRSVNGIKVIPLADHIDNQMIYVKR
                     KDKNLSVAGATFVTILKDYFDKRRKALT"
     gene            complement(3349..3642)
                     /gene="rpmA"
                     /locus_tag="ACF4ZO_001843"
     CDS             complement(3349..3642)
                     /gene="rpmA"
                     /locus_tag="ACF4ZO_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HFD5487344.1"
                     /translation="MLKMNLANLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVSG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPVAK"
     gene            complement(3670..3996)
                     /locus_tag="ACF4ZO_001844"
     CDS             complement(3670..3996)
                     /locus_tag="ACF4ZO_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HFD5487345.1"
                     /translation="MIKAIFTRQKNGQLSSVTLTGHAGSGKHGFDIVCASVSTLAINF
                     VNSLEVLADCQALVDLNDVEGGYMAITIPPHDNKEEVQLLFESFLLGMTSLAKDSSKF
                     VNTQVI"
     gene            complement(4008..4322)
                     /gene="rplU"
                     /locus_tag="ACF4ZO_001845"
     CDS             complement(4008..4322)
                     /gene="rplU"
                     /locus_tag="ACF4ZO_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HFD5487346.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAIYVEKIDAEAGAEVTFNEVVLVG
                     GDKTVVGTPVVEGATVVGTVEKQGKQKKVVTFKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     misc_feature    complement(4357..4431)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
BASE COUNT         1428 a          925 c          764 g         1407 t
ORIGIN      
        1 actcactaag ttatcgatgg ccgcgcggat ggtacgacca gtataaagca catcatcaat
       61 caaaatcaca tccttgcctg taatatctac tgacatcaga gttgtgtctt cctcaactct
      121 catatcatct ctaaaaggct tggtgtctaa ctcaccaatt ggtaaatcca acccttctaa
      181 ttgatgcagt ctttcttgaa tgcgacgagc tagaaaaaca cctctcgttt tgatacctgc
      241 caaaaccaca ttgtctaatt gtttattacg ttcaataatt tcataagtaa tacgggtaat
      301 ggcgcgtttc atggtcacgt catcaacaat ttccttagtt ttcatgttga aacctcctct
      361 aaaaattcaa ataaaaagat ctccttggaa acaaggagat tcagcaaaat atagcacaat
      421 taagtatcat ggtgcatgtt tttaatccgt ctccttgaca gcctcacagg actgttttaa
      481 aggaatattt tatttcaatc agtatagcaa aaaaagaaaa gaaaaacaag taaaaaaggc
      541 aatacctagc atctatttgg aatatctctt ttctttaagg agtttaaata aagatctcta
      601 acagatatgt tgcatatccc aataacataa aagacttctc atatttcctg gcttatcgta
      661 aatgcttttt agtatttttt ataatgttaa aaactttaca caaagatata agactaaaaa
      721 taatggctac tcctcgctgt ttattttttt cttagcagct ttaacacctt ttgaaaaatt
      781 tcgggagctt caacagtaaa tatcatttct tttcctgtca taggatgcgt taatcccaat
      841 gtttttgcat gaagaaattg gccatgacct gatagtgtct tacgtggtcc atataaaggg
      901 tccccagcaa caggatgacc aatataggcc atatgaacac gaatttggtg cgttcgacca
      961 gtttccagtt gtaattccac tagactgtaa tcgccaaaac gttctagcac tgtaaaacgt
     1021 gtcactgctt ctttgccttt tgctgtaaca gcctgttttt tacggtcctt ttcgctacga
     1081 cctataggag cttcaatcat ccctcgatca ttcggtaggt ttccatggac aatggcgagg
     1141 tattttctga gagatttttt agcctttaat tcttctgcca aggcttgatg agctgcatct
     1201 gttttagcta ccattaagag acctgaggtg tccttatcaa tccgatgaac aattcctgga
     1261 cgaaccacac cattgattga ggacaaatcc ttgatatgat acatcaaggc attaaccatt
     1321 gttcctgaag ggtgtcccgc cgaagggtga actaccattc cctgtggctt gttaataatg
     1381 gcgagagcat catcttcata gataatgtcc aagggaatat tctgagcttg gtactctaag
     1441 acttcttctt tagggagttc aaaacaaatc acatctcctg cttgaaccgt atatttagcc
     1501 tttttttgct gaccattaac taaaacaagg ccttgcttaa tttggtcatt ggcttgacca
     1561 cgtgacaggg gacttaaatc agctagtgcc ttatccaagc gttgccccga tgttatcaca
     1621 ttaatctcca taatcctctt ctttccataa acatatcact aataatatga caccaacggt
     1681 aaggtatgaa tctgccacat taaaaatggc aaaatccaca aagtctaaat gaaccatatc
     1741 aatcacgtaa gctaaacgca aacgatcaat aaaattcccg attccaccag aaataataag
     1801 caagagagct aattgtttcc agatatttaa atggggatga gtagcaaggt aataaatagc
     1861 ataaccgata actaaaaccg ttatggcaac aaagaaccat tgctggtcct gcaatatgga
     1921 aaaggcagcc ccattgtttt gcaagtaagt caagctgacg atacctggga taaagggttt
     1981 cacttctcca agcgctatat gagaaacaat ccaaaattta ctaagttgat ccaaagctac
     2041 aaggaggatc aagctaagca caaacaatcg ttttttcatg ttaaggcctt ccttctttta
     2101 tcaaaatagt cttttaaaat agtcacaaaa gtggccccag caacagaaag gtttttatct
     2161 tttcgtttga cataaatcat ttgattgtca atatgatcag ctagaggtat cactttaatc
     2221 ccattaacac tccgatgatc gagaaaacct gatcctgtcg caaaggcatt ggttctctct
     2281 aaaataccgt tcaaagttgc cctatctgac acattataaa tacgagggca ttcactagta
     2341 tccacaaaat tttcagaata atacaaatac tcgtcccttt cttgggtaaa ccttaccgca
     2401 ggtaatcctt gaatatcgtt caaataaagc gcttcgtgat tagccaatgg atgcgttttt
     2461 gaaagataaa tatgagtagt gaaaggaatt agagaaacat attccaagcc caacttatcc
     2521 atccgctgaa agagaccttt ttgattgtct acattcaagt aaataatacc aatttcactg
     2581 tttccttgag caacttcatc taaaatttga atagttgttg attcaaagat acgaaagaca
     2641 cgatgaccat cgtattgttg cgaaaaagct gtaataagag gtggcaaaaa gtcataatgt
     2701 tggctagcaa tagaaaattc attttgatcc agatcagctt gagaaaaggt tttttcaaaa
     2761 gaatcaaaag atttgactac ttctaaagct ttctcataaa aaactagtcc ttgacttgtc
     2821 aagactgttc ctgaagtagt ccgattaaaa atttgaaacc ctaattccgc ctctaaatct
     2881 ttgatagaaa ctgataagct aggctgactg acaaacaatt tagaggcagc ttctcgaaaa
     2941 gttccattat tagcgatggc taccacatag cgtaattgtt gaatattcat tgctttcctt
     3001 cctaaaatga gtatccttaa ttataccata aagcccgtta taacaacatc ttatgacatt
     3061 gttttattat ctgacttttt acaatcagaa ctattgctct aaatcagcaa ctgcaatctt
     3121 tagtaggata gaaacaaaca atgaaaatcc aatacacttg gtcgtgaaac tatccaaact
     3181 accatgaata tctacgctca tgttactaaa tcctcaaaag ataaaactgc tgacaagctc
     3241 tcttcctaca tcggctttta gaatatgggt agcaaatggg tagcaaaata aaaaaaaaat
     3301 cggctttcca gacacctgga aagccttata taatgcgatg ttaaacaatt atttagctac
     3361 tgggtaaaca gaaacttgtt ttttatcgcg tcctttacgt tcgaaacgta caacaccttc
     3421 aactttagca aaaagtgtgt catctccacc acggcctacg tttacacctg ggtagatatg
     3481 agttccacgt tgacggtaaa ggattgatcc acctgaaaca gtttgaccgt cagcagcttt
     3541 agcaccaagg cgtttagctt gtgagtcacg tccgtttgat gtagaacctc cacctttttt
     3601 gtgggcgaaa agttgcaagt tagcaagatt catttttaac ataatgttgt ttcctctctt
     3661 aaattaaatt tagatgacct gagtgttgac aaatttcgaa gaatccttcg ccaaactagt
     3721 cattcctaga agaaaagact caaataataa ttgaacttcc tccttgttgt catgtggtgg
     3781 tattgtaata gccatatacc caccttcaac atcattaaga tctactaatg cttggcaatc
     3841 tgctaacacc tcaagagaat taacaaagtt aatggctaga gtactaacag aggcacaaac
     3901 aatatcaaag ccatgtttac cactaccagc atgacctgtc agtgtaacac tgctcagttg
     3961 accatttttt tggcgagtaa aaattgcttt aatcataagc tagtaaatta agcgttgatt
     4021 gcgttgatga caactttagt gtaaggttga cgatgacctt gtttacggtg gctacctttt
     4081 ttaggtttgt atttgaatgt tacaactttc ttttgttttc cttgtttttc aacagttcca
     4141 acgacagtag ctccttcaac aactggagta ccaactacag ttttgtcacc acctacaaga
     4201 acaacttcgt taaaagtgac ttctgcgcca gcttcagcgt caattttctc aacgtagatt
     4261 gcttgaccta cttcaacttt aacttgtttt ccaccagttt tgatgattgc gtatgtgctc
     4321 atgatgcacc tcctataaaa tttttgtttg aggtttccct ctgtgaagac tcgcctggaa
     4381 tcgtgagact tggtctactt gacaacgatt ttcgcgcggt tgcacaggat gtgcatttag
     4441 tcaacgttac tattttagca ccataactgc tttttatcaa ggaaaaatta agtttaatct
     4501 ctatttttta tcgttagatg ctaa
//
LOCUS       DAXMQE010000067         4207 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.067, whole genome shotgun sequence.
ACCESSION   DAXMQE010000067 DAXMQE010000000
VERSION     DAXMQE010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4207)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4207)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4207
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.067"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            134..574
                     /locus_tag="ACF4ZO_001846"
     CDS             134..574
                     /locus_tag="ACF4ZO_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family phage packaging/lysis
                     transcriptional regulator"
                     /protein_id="HFD5487347.1"
                     /translation="MTFFPEIDIQKTKSNAKRKLREYPRWRRIANDVDTQKVTATYSF
                     EPRQPHGTPSKPVERLALNRVSAEQELDTIERAVNGIFDPEYRLILIDKYLLTYPKTD
                     CDIYTKLGYEKSQYYNMLDNALLSFSELYKEGMLLVEKLEKSWN"
     gene            1038..1556
                     /locus_tag="ACF4ZO_001847"
     CDS             1038..1556
                     /locus_tag="ACF4ZO_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB N-terminal domain-containing protein"
                     /protein_id="HFD5487348.1"
                     /translation="MEFVDKKLSEITPYKNNPRNNDEAVEPVAESIKEFGFKVPIVVD
                     KNGEIVNGHTRYKAAQKLGLETVPVIVADDLSEEQIKAFRLADNKVSEIAVWDLDLLN
                     EELNDILDLDMSVFGFELEIDDENQENLDADFEEIEDDSVLIVEAESEEELEKLYDEF
                     VERGFKCRVSIL"
     gene            1535..2212
                     /locus_tag="ACF4ZO_001848"
     CDS             1535..2212
                     /locus_tag="ACF4ZO_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5487349.1"
                     /translation="MPSFNIVKKNDLNSSFKVSKVTADFDVGAEHVREHFIGKIDYPD
                     KWQIGLIVGGSGTGKSTIAKELYNEALEDDFVYPDKPVIDCIPCHNVEELQKMFYAVG
                     FGSVPSWLKPYHVLSNGEKMRVDLARRILTKEFIVFDEFTSVVDRQVAKIICIALKKA
                     LKRYPDKKFIAVGCHHDVIEFLQPDWCFNTDDMQQVFRFPHEANKNSQSEDAQLPSGE
                     NLDVIII"
     gene            2221..2604
                     /locus_tag="ACF4ZO_001849"
     CDS             2221..2604
                     /locus_tag="ACF4ZO_001849"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: protein motif:HMM:NF024898.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFD5487350.1"
                     /translation="MVRAARCFGLYDDDKIIGFIGVIHFPHPKNKKIKRVTRLVILPD
                     YQGVGLGTRFLKSVAEIYSCQGFDFRIVTSAKNLINALNRNTNWKLKSYDKGNTPTGN
                     SSIKQLAKTTRKNVKIASFLFVRKN"
     gene            2665..3042
                     /locus_tag="ACF4ZO_001850"
     CDS             2665..3042
                     /locus_tag="ACF4ZO_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HFD5487351.1"
                     /translation="MNKIEAIISIKPQFVDEIMKGNKRFEFRKSFLKSIPDRCYIYST
                     KPVGKIVGFFTIKQVLRDEPEKIWQKTSKKSGITKDFFDEYYSGKNKAVAIEIDRLFA
                     YKTPKNYHEIDIKGKPPQTYKTI"
     gene            3084..3566
                     /locus_tag="ACF4ZO_001851"
     CDS             3084..3566
                     /locus_tag="ACF4ZO_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5487352.1"
                     /translation="MRRLANEENLIPGNKRSKSELREITRKGGIASGKARRRKKELKT
                     IIEQALNSVIPNEKAQKKLESLGFDPTFQSAIALKVVEQAMNGNLRAVELISNISFAG
                     KDSLDRKEQRQRIKAAELATDEQRTRIELLKVKLDAEKGAKPDTSLMRALLDAVEGGD
                     "
     gene            3575..4207
                     /locus_tag="ACF4ZO_001852"
                     /pseudo
     CDS             3575..4207
                     /locus_tag="ACF4ZO_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986835.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
BASE COUNT         1489 a          647 c          875 g         1196 t
ORIGIN      
        1 ctgacatcgt acgcctgtgt caaaaaacaa aggaaagaga ggacttttct ccacaaaaca
       61 aaaagacgtc cacacggaac gcccccttgg ttaaatttaa gcttaaataa attataccat
      121 actgggggct ttcatgacgt tttttcctga gattgatatc caaaaaacaa aatccaacgc
      181 caagcgtaaa ttgagagagt atccacgctg gcggaggata gctaatgatg tagatactca
      241 aaaagttaca gctacttact cctttgagcc aagacaaccg catggaacgc caagcaagcc
      301 tgttgagaga ctagcgctca accgtgtgtc ggcagaacag gagctggata cgattgagag
      361 agcagtcaac gggatatttg atccagagta tagattgata ctgattgaca agtatttact
      421 cacatatcca aagactgatt gtgatattta tacaaaactt ggttatgaaa aaagccagta
      481 ttacaacatg ctagataatg ctttgttgtc gttctcagag ctatataaag agggaatgtt
      541 gcttgtcgaa aaattggaaa aaagctggaa ttaatatgga ataattatgt actttatata
      601 taattattca tgttattata gtactatcaa aataacaaga agagataacc ttttaaccac
      661 tgactattca tttagtcgcc aactttaact acgatcaaac ttgttatttt atggtatgtg
      721 ggacgtgcag gttcgaatcc tgccgtctct atcagcgtca ggggagacgc gaccccacac
      781 ccatttaaag gtagacacga tctgatgtgt ggggttttat gattaaccgc aagtaaaaca
      841 agggtcgcaa ccttgcttgt ggttagtagg gataacggtt gtaagtcggt tcgattccga
      901 ctgttcctgt ttgataaata gaagtgtccc aaaatggggt aggcaatagg cttagcattc
      961 atttgctatt tatctatggt taaccaatta gtcatcacat tgtggtgact ttttattatg
     1021 taaaaaagga ataaaacatg gagtttgtgg acaaaaaatt aagtgaaata acaccttata
     1081 aaaataaccc tagaaacaat gatgaggccg ttgaaccagt tgctgaatct attaaagagt
     1141 ttggttttaa agtgcctatt gtcgttgata aaaacggcga aatcgtgaac ggccacactc
     1201 gttataaagc agcccaaaaa ttagggctag aaacagttcc tgttattgtc gcagatgact
     1261 tatctgaaga gcaaatcaaa gcgttcagac ttgctgacaa taaagttagt gagattgcgg
     1321 tttgggattt agatttgtta aatgaagaat taaatgacat tttagatctt gatatgtctg
     1381 tttttggctt tgaattagaa atagatgacg agaatcaaga gaatttagat gctgattttg
     1441 aagaaataga agatgactct gttttaatag tagaagctga aagcgaagag gaattggaaa
     1501 agttatatga cgaatttgta gaaagaggtt tcaaatgccg agtttcaata ttgtaaaaaa
     1561 gaacgactta aatagttctt ttaaagtttc caaagtaacg gctgactttg atgtcggcgc
     1621 agaacacgtt agagaacatt ttattggaaa aatagactat cccgataaat ggcagatagg
     1681 tttaattgta ggcggaagtg gaacaggaaa aagcactatc gctaaagagt tgtataacga
     1741 agcgttagaa gatgactttg tttatcctga taaacctgtt atagattgca taccatgcca
     1801 caatgttgaa gaattacaaa aaatgttcta tgcggttggg tttgggagtg ttccttcttg
     1861 gctcaagcct tatcatgttt tatcaaatgg cgaaaaaatg cgtgttgatt tagctaggcg
     1921 aatattaaca aaagagttta tcgtttttga tgagtttact agtgttgttg atagacaagt
     1981 cgctaaaata atttgtatag cgttaaaaaa agctttaaaa agatatcctg acaagaaatt
     2041 tatcgcagtt ggttgtcatc atgatgtaat tgagttttta caaccagatt ggtgttttaa
     2101 tacagatgat atgcaacagg tttttcgatt cccccacgaa gcaaacaaga attcacagtc
     2161 agaagatgct caattgccga gtggggaaaa tttagacgtt atcattatct aaatggagat
     2221 atagttagag ccgcacgttg ttttgggcta tatgatgatg ataaaataat aggatttatt
     2281 ggggtaatac actttccaca tcctaaaaat aaaaaaatca aaagagttac taggttggtt
     2341 attttacctg attatcaagg tgtaggatta ggtactagat ttttaaaatc agtagctgaa
     2401 atatattctt gtcaagggtt tgactttcgg attgtcacga gcgctaaaaa tcttattaat
     2461 gcgttaaata gaaatactaa ttggaaattg aaaagttacg ataaaggaaa tactccaacg
     2521 ggaaattctt cgattaaaca acttgcaaaa acaactagaa aaaacgttaa aatagctagc
     2581 tttctttttg taagaaaaaa ttaactcctc tcttgaaccg ttcaaatctg ttccttataa
     2641 taaaataaaa aggaatgaga aataatgaat aaaatagagg ctataatttc aatcaaacct
     2701 caatttgtag atgagataat gaaaggtaac aagcgttttg aatttagaaa atctttttta
     2761 aaaagtattc ctgatagatg ttacatttac tctacaaaac ctgtaggcaa gatagttggt
     2821 ttttttacca ttaaacaagt tttaagagat gaaccggaaa aaatatggca aaaaacaagt
     2881 aaaaagtcag ggattacaaa ggattttttt gacgaatatt attcaggaaa aaataaagcg
     2941 gtagcaatag aaatagatag gttgtttgct tacaaaacac ctaagaatta tcatgaaata
     3001 gatataaaag ggaagccacc gcaaacatat aaaacgattt gaagaagctg attgcttctt
     3061 tttttatttt taaaagtaag gaagtgaggc gattggctaa tgaagaaaac ttaataccag
     3121 gaaataaacg aagtaagagt gaacttagag aaatcactag aaaaggcggt atagcttccg
     3181 gtaaagcaag aagacgcaaa aaagaattaa aaaccataat cgaacaagcg ctcaactctg
     3241 ttatcccaaa tgaaaaagca caaaaaaagt tagaaagtct aggttttgat ccaacatttc
     3301 agtcagctat cgctttgaaa gtggtcgaac aagcgatgaa tgggaattta agagctgttg
     3361 aattaatatc taatatatct tttgcaggaa aagatagcct ggatagaaaa gaacaaagac
     3421 agcgaattaa ggccgcggag ctcgccacag acgagcaacg aacgcgcatc gagctgctta
     3481 aagtcaaact tgacgcagag aaaggcgcta agcctgatac tagcttaatg agagctttgt
     3541 tagatgctgt ggaaggaggt gattagcctt ggagattatc ttttcaaata aacaaaaaga
     3601 cgtcattaga cgccctttta actacgaatt agaggtcaac gagggcactt gacccctcgt
     3661 agcggaaaga ccacagctgg gcattttcgt tatgctaggt atctgattga gtcagaagat
     3721 gaaaatcacc ttgtgactgc ttataatcaa gaacaagctt atcgtttgtt tatcgacggc
     3781 gatggtacgg gtttgatgca tatatttgac ggtaactgcg aaataaaaca cgatgagcgt
     3841 ggagatcact tgttaatcat gactccaaaa ggcaataagc gtgtttatta taaaggtggc
     3901 ggtaaggtta atagcgttgg tgctattaca ggtatgtctt taggatcagt agtattctgc
     3961 gagattaact tactgcacat ggattttatc caggagtgtt ttaggcgtac ttgggcggct
     4021 acgctacgtt atcatctagc agatttaaat ccaccagcac ctcaacatcc agtaattaaa
     4081 gatgtctttg atgttcagaa cacgaggtgg acgcattgga ccatggatga taacccaata
     4141 ctaacagcag agcgtaaaca aaacattatc aacagtctta aaaaaaatcc atatctatac
     4201 aaacgag
//
LOCUS       DAXMQE010000068         4111 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.068, whole genome shotgun sequence.
ACCESSION   DAXMQE010000068 DAXMQE010000000
VERSION     DAXMQE010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4111)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4111)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4111
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.068"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            <1..2002
                     /gene="ppc"
                     /locus_tag="ACF4ZO_001853"
     CDS             <1..2002
                     /gene="ppc"
                     /locus_tag="ACF4ZO_001853"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015055932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008964 - phosphoenolpyruvate carboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA];
                     GO_process: GO:0015977 - carbon fixation [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HFD5487353.1"
                     /translation="PFVTAETLCLSATVQSEVILNYYIDKLAALYRTFSLSSTLVQPN
                     SEVERLASLSQDQSIYRGNEPYRRAFHYIQSRLKQTQIQLTNQPAARMSSSVGLSTSA
                     WSSPASLENPILAYDSPVDFKADLKAIEQSLLDNGNSALIEGDLREVMQAVDIFGFFL
                     ASIDMRQDSSVQEACVAELLKGANIVDDYSSLSETEKCDVLVQQLMEEPRTLSSAAVA
                     KSDLLEKELAIYTTARELKDKLGEEVIKQHIISHTESVSDMFELAIMLKEVGLVDQQR
                     ARVQIVPLFETIEDLDNARDIMAAYLSHDIVKSWIATNRNYQEIMLGYSDSNKDGGYL
                     ASGWTLYKAQNELTAIGEEHGVKITFFHGRGGTVGRGGGPSYDAITSQPFGSIKDRIR
                     LTEQGEIIENKYGNKDVAYYHLEMLISASINRMVTQMITDPNEIDSFREIMDSIVADS
                     NIIYRKLVFDNPHFYDYFFEASPIKEVSSLNIGSRPAARKTITEITGLRAIPWVFSWS
                     QNRIMFPGWYGVGSAFKRYIDRAQGNLERLQHMYQTWPFFHSLLSNVDMVLSKSNMNI
                     AFQYAQLAESQDVRDVFYEILDEWQLTKNVILAIQDHDDLLEDNPSLKHSLKSRLPYF
                     NVLNYIQIELIKRWRNNQLDENDEKLIHTTINGIATGLRNSG"
     gene            2172..3446
                     /locus_tag="ACF4ZO_001854"
     CDS             2172..3446
                     /locus_tag="ACF4ZO_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HFD5487354.1"
                     /translation="MKIDKRHLLNYSILLPYLILSVIGLIMVYSTTSVSLIQAHANPF
                     KSVINQGVFWIISLVAITFIYKLKLNFLTNTRVLTVVMLGEAFLLIIARFFTTAIKGA
                     HGWIVIGPVSFQPAEYLKIIMVWYLALTFAKIQKNISLYDYQALTRRKWWPTQWNDLR
                     DWRVYSLLMVLLVAAQPDLGNASIIVLTAIIMFSISGIGYRWFSAILVMITGLSTVFL
                     GTIAVIGVERVAKIPVFGYVAKRFSAFFNPFHDLTDSGHQLANSYYAMSNGGWFGQGL
                     GNSIEKRGYLPEAQTDFVFSVVIEELGLIGAGFILALVFFLILRIMNVGIKAKNPFNA
                     MMALGVGGMMLMQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVGFVLNIDAS
                     EKRDDIFKEAELSYRKDTRKENSKVVNIKQFQ"
     gene            3800..>4111
                     /locus_tag="ACF4ZO_001855"
     CDS             3800..>4111
                     /locus_tag="ACF4ZO_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HFD5487355.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETATRHYAHIDAPGHADYVKNMITGAAQM
                     DG"
BASE COUNT         1218 a          743 c          840 g         1310 t
ORIGIN      
        1 cccctttgtc acagctgaaa ccttgtgctt gtcagctacg gttcaaagtg aggttatcct
       61 caattactac attgacaaat tagcagccct ttaccgaaca ttttcactgt cgtcaacctt
      121 ggtacaaccc aactcggaag tggaacgttt agccagtttg tctcaggacc aatcgattta
      181 ccgtggaaat gaaccttatc gcagagcttt tcattatatt caatcgcgtc ttaaacaaac
      241 acaaattcaa ctaactaatc agccagcagc tcgtatgagt agtagtgtgg gactaagcac
      301 atctgcttgg tcctcaccag ctagtttaga aaatcccatc ttagcctatg actctcctgt
      361 tgattttaaa gctgatctaa aggctattga gcagtcgcta cttgataatg gcaactccgc
      421 tttgattgag ggggatttgc gagaagtcat gcaagctgtt gatatttttg gcttcttctt
      481 agcaagcatt gacatgaggc aagactccag tgtccaagaa gcttgtgtgg cagagttatt
      541 aaaaggagcc aatattgttg acgattatag ctctctttca gaaactgaaa aatgcgatgt
      601 tctcgtacaa caattaatgg aggagccaag gaccttatcc tcagcggcag ttgctaaatc
      661 agacctatta gaaaaagaac tggctatcta tactacggca cgagaattga aagataagct
      721 tggagaagag gtcattaagc aacatattat ttcacataca gaaagtgtct ctgatatgtt
      781 tgagttggcc atcatgctta aagaagtggg attggttgac cagcagcggg ctcgtgtgca
      841 aattgttccc ctctttgaaa ccattgagga cttagataat gcccgtgaca tcatggcagc
      901 ctatttaagc catgacattg tcaaatcttg gattgcaacg aatcgtaatt accaagaaat
      961 catgttaggt tattctgaca gtaataaaga tggtggctac ttggcatcgg gttggactct
     1021 ttataaagct cagaatgaat taacggctat tggtgaggaa catggagtga aaatcacctt
     1081 cttccatggt cgtggaggaa cagttggtcg aggaggtggc ccttcttatg atgccattac
     1141 ttcacaacct tttggttcca tcaaagatcg gattcgtctg acagagcaag gggaaattat
     1201 tgaaaacaaa tacggcaata aagatgtggc ttattaccat ttagaaatgt tgatttcagc
     1261 ttctatcaat cgtatggtga ctcaaatgat aacagatcct aatgagattg atagttttcg
     1321 agaaatcatg gatagcattg ttgctgatag caatatcatt tatcgaaaat tggtttttga
     1381 caatccccat ttctatgatt atttctttga ggcaagcccg attaaggaag tttccagtct
     1441 caacattggg tcaagaccag cagcccgtaa aacgattacg gaaattacag gcttgcgtgc
     1501 cattccttgg gtcttttcat ggtcacaaaa tcgcatcatg ttcccaggtt ggtatggggt
     1561 aggttcagcc tttaaacgtt atattgaccg agcacaaggt aaccttgaac gcctccaaca
     1621 catgtatcag acgtggcctt ttttccattc cttgttatca aatgttgata tggtattatc
     1681 taaatcaaac atgaatattg cctttcagta tgcacaacta gctgaaagtc aggatgttcg
     1741 agatgttttt tatgagattt tggatgagtg gcaattgaca aaaaatgtta ttcttgctat
     1801 ccaagaccat gatgatctat tggaggataa tccttccctt aagcatagct tgaagtcacg
     1861 cttgccgtat tttaatgtgt tgaactatat tcaaattgaa ttgattaaac gttggcgtaa
     1921 taatcaactt gacgaaaatg atgaaaaatt gatccataca actatcaatg gcatagcgac
     1981 tggtttacgt aattcaggct aatgctcttg agtattaatt ggtatttata gaagttttca
     2041 agtgactaat cagaatttta aaggttagcc cttggagctt ctttttttga ggattcttga
     2101 ctttttcttt tgtttgatat agaaagatgt tataatgcta aatgattatc tcaagaagta
     2161 gagggaaaac tatgaagatt gataaaaggc acctcttaaa ttattctata ttattgcctt
     2221 atttaatttt atcggtgata ggcttaataa tggtttactc aaccacaagt gtcagcttga
     2281 ttcaagcaca tgctaatcca tttaaatcag tgattaacca gggagttttt tggataataa
     2341 gtctagtggc tattacattt atctataaat taaaattaaa ttttttaacg aatacaaggg
     2401 tattaactgt ggttatgtta ggagaggcct ttcttttaat tattgcccgc ttctttacaa
     2461 ctgctatcaa aggagcgcat ggttggattg tgatcggacc agtcagcttt cagcctgctg
     2521 agtatttaaa gatcattatg gtatggtatt tggcattgac ctttgctaag atccaaaaaa
     2581 acattagcct ttatgattat caagcactaa ctcgtcgaaa atggtggcca acacaatgga
     2641 acgatttacg ggactggcgt gtttattctt tgttgatggt acttttggtt gctgctcagc
     2701 ctgacttggg aaatgcttcc attattgtat tgacagccat tattatgttt tctatcagtg
     2761 gcattggtta ccgatggttt tcggctatcc tagtcatgat taccggtcta tccacggtct
     2821 ttcttgggac tattgccgtt attggggtag aaagagttgc taagattcct gtttttggct
     2881 atgtcgctaa acgttttagt gcttttttta atcctttcca tgacttgacc gattcaggtc
     2941 accaattagc caattcttac tatgctatga gtaatggtgg gtggtttggc caagggttag
     3001 gaaattccat tgaaaagcgt ggttatttgc ccgaagcaca gacagacttt gtcttttcag
     3061 ttgtcattga agagttaggt ctaataggag cagggtttat tttggcactt gttttcttct
     3121 taattttacg tattatgaat gttggtatta aagcaaaaaa tccttttaat gccatgatgg
     3181 ctttaggagt aggcggtatg atgctcatgc aagtctttgt taatattggt ggtatctcag
     3241 ggttaattcc atctactggt gttaccttcc cttttttgtc tcaaggtgga aatagcttac
     3301 ttgtcttatc tgttgcagtg ggttttgtac taaatattga tgctagcgaa aagcgagatg
     3361 atatatttaa agaagctgaa ttatcttatc gaaaggatac tcgaaaagaa aatagtaaag
     3421 ttgtaaatat caagcaattt caataatatt ctaaaatctc ctttaaggag attttagaat
     3481 atagacaatc ccagtttgat gctcaaaaaa cttgaactgc tctgctgatt tcttattttt
     3541 gcgtgtgaca tgagccaaaa cagctgcttt ttgctgtggc aaaaataaag cgtggaattc
     3601 caaaggaagt cgctgctata agcaccacct aaggagagta tcaaaaaaga ctttttcatc
     3661 tatttaaaaa ataaagaaat ggcaaaaaac ataaaatact tgcattttca ttgtaatttg
     3721 ctacaatagt aaggtaaagt tagactgtat ggcctaccgt ctatctataa aatatatttt
     3781 attggaggct tttcctaaaa tggcaaaaga aaaatacgat cgtagtaaac cccacgttaa
     3841 cattggtaca atcggacacg ttgaccatgg taaaactact ttaacagctg caatcacaac
     3901 tgtattggca cgtcgcttgc cttcatcagt taaccaacca aaagattacg cttctatcga
     3961 tgctgctcca gaagaacgcg aacgcggaat cactatcaac actgcacacg ttgagtacga
     4021 aactgcaact cgtcactatg cgcacatcga cgctccagga cacgcggact acgttaaaaa
     4081 catgatcact ggtgccgctc aaatggacgg a
//
LOCUS       DAXMQE010000069         4030 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.069, whole genome shotgun sequence.
ACCESSION   DAXMQE010000069 DAXMQE010000000
VERSION     DAXMQE010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4030)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4030)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4030
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.069"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            <1..721
                     /locus_tag="ACF4ZO_001856"
     CDS             <1..721
                     /locus_tag="ACF4ZO_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HFD5487356.1"
                     /translation="TFKQANTYATGPLFMSVGNTLFGENGEDVKGTNWGNEKGAAVLK
                     WIADQASNKGFVSLDANNVMSKFGDGSVASFESGPWDYEAAQKAIGKENLGVAIYPKV
                     TIGGETVQQKAFLGVKLYAVNQAPAKGDTKRIAASYKLASYLTNAESQENQFKTRNIV
                     PANKEVQSSEAVQSNELAKTVITMGSSSDYTVVMPKLSQMGTFWTESAAILSDAFNGK
                     IKESDYLTKLQQFDKDIAATK"
     gene            995..2356
                     /locus_tag="ACF4ZO_001857"
     CDS             995..2356
                     /locus_tag="ACF4ZO_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFD5487357.1"
                     /translation="MTQSNLTPNISVIEALKRGSWDIKLSSIIMGFANFANKQFIKGI
                     LFLISELIFLVAFVSQIIPAIRGLVTLGTQTQGMTTKTIDGINIQVAVDGDNSMLMLI
                     FGLASLIFCLVFAYIYWCNLKSARNLYLFKQKGQKMPSFKEDLATLTNGRFHMTLMAI
                     PLIGVLLFTILPLIYMICLAFTNFDHNHLPPKSLFDWVGLANFGNVLSGRMAGTFFPI
                     FSWTLIWAVFATVTNFFFGIILALLINTKGLKWKKMWRTIFVITIAVPQFISLLIMRN
                     LLNDEGPLNALLNKIGLINGSLPFLSDPLWAKFSIIFVNMWIGIPFTMLIATGIIMNL
                     PSEQIEAAEIDGASKFQVFKSITFPQILLIMTPNLIQQFIGNINNFNVIYLLTGGGPT
                     NSEYYQAGTTDLLVTWLYKLTVTAADYNLASVIGILIFTVSAIFSLLAYTRTASYKEG
                     AAK"
     gene            2356..3192
                     /locus_tag="ACF4ZO_001858"
     CDS             2356..3192
                     /locus_tag="ACF4ZO_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HFD5487358.1"
                     /translation="MKNKRRFQLGLVYATLIILSIIWLFPIAWVILTSFRSEGTAYVN
                     YFIPKTFTLNHYINLFTNETFPFGKWFMNTLIVATFTCIISTFITVAIAYSLSRIKFK
                     FRNGFLKLALILNMFPGFMSMIAIYYILKALGLTQTLTALVLVYSSGAALGFYIAKGF
                     FDTIPYSLDESAMIDGATRMDIFFKITLPLAKPIIVYTALLAFMGPWIDFIFAQVILG
                     DATSKYTVAIGLFSMLQPDTINNWFMAFTAGSVLIAVPITLLFMFMQKYYVEGITGGS
                     VK"
     gene            3379..4030
                     /locus_tag="ACF4ZO_001859"
                     /pseudo
     CDS             3379..4030
                     /locus_tag="ACF4ZO_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001871253.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
BASE COUNT         1209 a          823 c          693 g         1305 t
ORIGIN      
        1 tacctttaaa caagctaaca cttacgctac tggtccatta ttcatgtcag ttggtaacac
       61 tttatttggg gaaaacggtg aagatgtaaa aggtactaac tggggcaatg aaaaaggcgc
      121 tgctgttctt aaatggatcg cagaccaagc ttcaaataaa ggttttgtta gcttagatgc
      181 taacaacgtt atgtctaaat ttggtgacgg atcagtagct tcctttgaat caggaccgtg
      241 ggactatgaa gctgctcaaa aagctatcgg taaagaaaac cttggtgttg ctatttatcc
      301 aaaagtaact attggaggcg aaacggttca acaaaaagca ttcttgggtg taaaacttta
      361 cgcagtcaac caagcaccag ctaaaggtga tacaaaacgt atcgcagcta gctacaaatt
      421 ggcatcctac ttgactaatg ctgaaagcca agaaaaccaa ttcaaaactc gtaacattgt
      481 cccagccaac aaagaagttc aatcttcaga agctgttcaa tcaaatgaac ttgctaaaac
      541 cgttatcact atgggttctt cttcagacta cactgtcgta atgccaaaac ttagccaaat
      601 gggcacattc tggactgaaa gtgctgctat tcttagtgat gccttcaacg gtaaaatcaa
      661 agaaagcgac taccttacta agttgcaaca attcgacaaa gatatcgctg caacaaaata
      721 atatgatctc atgtcatcac tgctatacta aaacaagcac aaggtaagta cttctaaaaa
      781 gttctttcca cttaccttat gaagagtgga actaggctcc atcacatttt attcaagctt
      841 agtctcactc ttacttgttt ttgttttact agtagcttag tgctacttaa atttttaact
      901 ctttaaaagt ttacgtaaca cttagctatt tcatcctaac aagagattga atctgaacta
      961 ccactctagt atcctaaaat aaaggagaat ctatatgact cagtcaaact tgacaccaaa
     1021 tatatctgta atagaagcct taaaaagagg cagttgggat attaaacttt cgagtattat
     1081 catgggattt gccaactttg ctaacaaaca gtttatcaaa ggaatcttat ttttaataag
     1141 tgaacttatc tttctagtag cttttgtctc ccaaatcatc cctgctatcc gtggccttgt
     1201 cactcttggt actcaaactc agggaatgac tacaaaaact attgatggga ttaacatcca
     1261 agttgctgtt gatggcgata actctatgct aatgcttatt tttggtttag catcactcat
     1321 tttctgccta gtctttgctt acatttactg gtgtaatctc aaaagtgctc gtaaccttta
     1381 tcttttcaaa caaaaaggtc agaagatgcc aagcttcaaa gaagatcttg ccacacttac
     1441 aaatggtcgc tttcatatga ctttaatggc tatcccactg attggtgtgc ttttattcac
     1501 cattcttcct ttgatttaca tgatctgttt agcctttacc aattttgatc ataatcactt
     1561 gcctccaaaa tctttatttg attgggtggg acttgctaac tttggaaatg ttttaagcgg
     1621 ccgtatggca ggaacctttt ttcctatctt ctcatggact ttgatttggg ctgtttttgc
     1681 cacagtaact aatttcttct ttggtattat tcttgctttg ttaatcaata ccaaaggatt
     1741 aaagtggaaa aaaatgtggc gaaccatctt tgttatcacc attgcagttc cacaattcat
     1801 ctcattattg attatgcgga acttactcaa tgacgaaggc ccactaaatg ctcttctcaa
     1861 taaaatcggc ttgattaatg gctcactgcc atttttatct gatcctcttt gggcaaaatt
     1921 ctcaatcatt tttgtcaaca tgtggatcgg tattccattt accatgttga ttgcgactgg
     1981 tattatcatg aaccttccaa gtgaacaaat tgaggctgct gaaattgatg gtgctagcaa
     2041 attccaagtc ttcaagtcta tcacgttccc tcaaattctc ttgatcatga caccaaactt
     2101 gattcaacaa tttatcggaa atatcaataa ctttaacgtc atttacctcc ttactggtgg
     2161 tggtccaaca aattcagaat actatcaggc aggaacaaca gacttgctgg tcacttggct
     2221 ctataaatta accgtcacag ctgctgacta caatttagct tctgttatcg gtatcttaat
     2281 ctttacagtt tcagctatct ttagcttact tgcttataca aggacagcat cctacaagga
     2341 aggagcggct aaataatgaa aaacaaacgt cgatttcaac ttggacttgt ttatgctact
     2401 ttaatcatcc tctcaatcat ttggctcttc ccaatcgctt gggttattct tactagcttc
     2461 cgtagcgaag gaactgctta cgtcaattat tttattccta agacttttac attaaatcac
     2521 tacattaatc tttttactaa tgaaaccttt ccttttggaa aatggtttat gaatactctt
     2581 attgtagcca cttttacatg tattatttca accttcataa ctgttgccat agcctactct
     2641 cttagccgaa ttaagtttaa gtttcgcaat ggctttttaa aactagccct tattttaaat
     2701 atgttccctg gtttcatgag catgattgcc atctactata tcttaaaggc cttaggtttg
     2761 acgcaaaccc taacagcact tgtccttgtt tattcctcag gtgcagccct tggtttttac
     2821 attgcaaaag gattttttga taccattcct tattcacttg atgaatcagc tatgattgat
     2881 ggcgctactc gtatggatat tttctttaaa ataacccttc ctttagcaaa accaatcatt
     2941 gtctatactg cccttcttgc ttttatgggg ccttggattg actttatctt tgcacaagtt
     3001 attttaggtg atgctacaag taaatatacc gttgctattg gactattttc aatgcttcag
     3061 ccagatacca ttaacaactg gtttatggcc ttcactgctg gttcggtctt aattgccgtc
     3121 ccaatcactc tcctcttcat gtttatgcaa aaatactatg ttgaaggcat cacaggtggt
     3181 tctgttaaat aagttacaac ataccaaacc ttctaagggt aagcccttta ggaggttttt
     3241 gataaataag gccgtagata atcatattag tcctcacatt tatcttcaga tcccgcgttg
     3301 taaaatgaag tgcaacaaaa aagacatgtt cgtctgatat actagaattc cccaattcag
     3361 tatggaaagt agatgaacat gtctaatatt aattctacca gaaaatcctc ctattctcat
     3421 ctttcagcca cagaacggga ggaaattgct gcttatctca aaatgggaaa gaaacccgtt
     3481 gagattgctc gactcctggg tcgtcaccgt tctacaatct gccgagaaat aaaacgtggt
     3541 tcagtagatc aggtaaagga taagaatgga aaacaaacct tcttcaacgc ctatttcgct
     3601 gatagtgggc aacgtgtcta ttaaaccaat cgatttgcct aagatggtta gtatcagaaa
     3661 acgttctaag aaagtcatga aaacgaataa gaagacttta ggtaaatcta tcgaagaacg
     3721 tccagaatat attaatgatc gttctgaatt tgggcattgg gagattgatt tgattctcgg
     3781 caagaaaacc aaaggtgaag ctgttatgtt gactttggta gagcgccaga cacgctatgc
     3841 actaggagtt aagctagaag acaagcagtc ccaaaccatt aaccgtgctg tcacgcatct
     3901 catcagtcag tatcctattg catccatcac agcagataat ggttctgagt ttagtttact
     3961 ctcaacctta gaagctgttg acgtttactt tgcatatccc tattcttcac atgagagagg
     4021 aacaaacgag
//
LOCUS       DAXMQE010000070         3259 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.070, whole genome shotgun sequence.
ACCESSION   DAXMQE010000070 DAXMQE010000000
VERSION     DAXMQE010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3259)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3259)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3259
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.070"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            complement(197..1591)
                     /locus_tag="ACF4ZO_001860"
     CDS             complement(197..1591)
                     /locus_tag="ACF4ZO_001860"
                     /EC_number="4.1.1.112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oxaloacetate decarboxylase subunit alpha"
                     /protein_id="HFD5487359.1"
                     /translation="MTKIRITETVLRDGQQSQIATRMTTKEMIPILETLDNAGYHALE
                     MWGGATFDSCLRFLNEDPWERLRAIRKAVKKTKLQMLLRGQNLLGYRNYADDVVRSFI
                     QKSIENGIDIVRIFDALNDPRNLQTAVSATKKFGGHAQVAISYTTSPVHTIDYFVELA
                     KAYQAIGADSICIKDMAGVLTPEIGYQLVKCIKENTTIPLEVHTHATSGISEMTYLKV
                     AEAGADIIDTAISSFSGGTSQPATESMAIALTDLGFDTGLDMQEVAKVAEYFNTIRDH
                     YREIGILNPKVKDTEPKTLIYQVPGGMLSNLLSQLTEQGLADKYEEVLAEVPKVRADL
                     GYPPLVTPLSQMVGTQALMNIISGERYKVVPNEIKDYVRGLYGQSPAPLAEGIKEKII
                     GDEAVITCRPADLIEPQMIYLRDEIAQYARSEEDVLSYASFPQQARDFLGRREDPFYD
                     VPVQEVTVQLDIQD"
     gene            complement(1606..2184)
                     /gene="citX"
                     /locus_tag="ACF4ZO_001861"
     CDS             complement(1606..2184)
                     /gene="citX"
                     /locus_tag="ACF4ZO_001861"
                     /EC_number="2.7.7.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050519 - holo-citrate lyase synthase
                     activity [Evidence IEA];
                     GO_process: GO:0051191 - prosthetic group biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase holo-[acyl-carrier protein]
                     synthase"
                     /protein_id="HFD5487360.1"
                     /translation="MSKEAYFSGESIQLSDMLRAREERALRQLHLLKEYPEGSLLSVT
                     MNIPGPIKTSPKLLEAFDIVIKAIQTALADDKICYQLRLLPTTGYEYYLITSLPSRDL
                     KLKMIALETELPIGRLMDLDVLVLQNDLPHSISRTVLGGSPRQCFICSKEAKVCGRLR
                     KHSVEEMQTAISKLLHSFFNKDNQSSSSDKTG"
     gene            complement(2177..>3259)
                     /gene="citF"
                     /locus_tag="ACF4ZO_001862"
     CDS             complement(2177..>3259)
                     /gene="citF"
                     /locus_tag="ACF4ZO_001862"
                     /EC_number="2.8.3.10"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014678010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009346 - ATP-independent citrate lyase
                     complex [Evidence IEA];
                     GO_function: GO:0008814 - citrate CoA-transferase activity
                     [Evidence IEA];
                     GO_function: GO:0008815 - citrate (pro-3S)-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006113 - fermentation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase subunit alpha"
                     /protein_id="HFD5487361.1"
                     /translation="RARAIASGDIHIDVAFLGAPSSDAYGNVNGTKGKATCGSLGYAM
                     IDAKYADQVVILTDNLVPYPNTPISIPQTDVDYVVTVDAIGDPQGIAKGATRFTKNPK
                     ELLIAEYAAKVITNSPYFKEGFSFQTGTGGASLAVTRFMREAMIKENIKASFALGGIT
                     NAMVELLEEGLVEKILDVQDFDHPSAVSLGKHAEHYEIDANMYASPLSKGAVINQLDT
                     CILSALEVDTNFNVNVMTGSDGVIRGASGGHCDTAFAAKMSLVISPLIRGRIPTFVDE
                     VNTVITPGTSVDVVVTEVGIAINPNRQDLVDHFKSLNVPQFSIEELKEKAYAIVGTPE
                     RIQYGDKVVALIEYRDGSLIDVVYNV"
BASE COUNT          916 a          698 c          666 g          979 t
ORIGIN      
        1 aaaacttctt tagattattt ttgttcgcta gaagcccaac ccattattca aaagatacaa
       61 gccacttcat ctgtcaaaca ttactaagat aaaaaaccta tctgattatc aaaatcagat
      121 aggtttttgg tattgttctt acagcaaatg cgtttcacca aggagattaa tggttaagag
      181 gattagtcat tccctgttag tcttgaatgt ccagttgtac agtaacttct tgaaccggaa
      241 catcatagaa aggatcttca cggcgtccca agaaatctct ggcttgctgt gggaaactcg
      301 catagcttaa cacgtcttct tctgaacgag cgtattgagc aatctcgtca cgtagataaa
      361 tcatttgagg ctcgattagg tcggctggtc tgcaagtaat aactgcttcg tcaccaatga
      421 ttttctcttt gataccttct gctaatgggg ctggtgattg accgtatagc cctcgaacat
      481 agtctttgat ttcatttgga actaccttgt agcgttcccc tgagatgata ttcatcaagg
      541 cctgtgtgcc aaccatttgt gataatggcg ttacaagtgg tggatatcca agatcggccc
      601 ttactttagg tacttctgct aagacttctt cgtatttatc agctaggcct tgctcggtta
      661 attggctcaa taggtttgat agcataccac ctggaacttg gtaaatcaat gtttttggct
      721 cagtgtcttt gactttagga tttaaaatcc ctatttctcg atagtggtca cgaatagtgt
      781 tgaaatattc tgcaactttg gccacctctt gcatatccaa gcctgtgtca aagcctaaat
      841 ccgtcaaggc aatcgccatt gactctgtgg caggctgact ggttccccct gaaaaagagg
      901 aaatcgccgt atcaataata tcagctcctg cttctgctac ttttaagtaa gtcatttctg
      961 aaataccact ggtagcatgg gtatgaacct caagagggat agttgtattc tccttgatac
     1021 atttgaccaa ttggtaacct atttcaggag ttaagacacc agccatgtct ttgatacaaa
     1081 tggagtcagc tccgatagct tggtaagctt tcgccaattc aacaaagtag tcaatggtat
     1141 gtaccggact tgtcgtgtaa gaaatggcaa cttgagcatg ccctccaaat tttttagtcg
     1201 ctgaaacagc tgtttgcaag ttgcgtgggt cgtttaaagc atcgaagata cggacaatat
     1261 caatcccgtt ttcaatggat ttttgaataa aggatctgac cacatcgtca gcataattgc
     1321 gatatccaag aaggttttgt ccgcgtaaga gcatctgaag tttagtcttt ttcactgctt
     1381 tacggatggc tcttagccgt tcccaagggt cttcatttaa aaagcgtagg caggaatcaa
     1441 aggttgctcc tccccacatt tcaagggcat gataaccagc attgtctaga gtttctagaa
     1501 taggaatcat ttccttggtt gtcatacgtg tggcaatctg actttgttga ccatcacgta
     1561 aaactgtttc cgttatacgg attttcgtca taattgttct cctcatcaac ctgtcttatc
     1621 tgatgacgat gattggttgt ctttattgaa aaatgaatgg agtaattttg aaatagcagt
     1681 ctgcatctcc tcgacactgt gcttacgtag gcgaccgcag actttggcct ctttagaaca
     1741 gataaaacat tgcctagggg agcctcctaa tacggttctg ctaattgaat gaggcagatc
     1801 attttgcaag accaagacat ctaagtccat gagacgacct attggcaact ctgtctctaa
     1861 ggctatcatt tttaacttca ggtcgcggct aggtagactt gtgatgaggt aatactcata
     1921 acccgttgta ggcagtaatc gcaactggta acaaatctta tcgtcagcta aggcagtttg
     1981 aatggcctta atcactatat caaaagcttc aagaagttta ggagaggttt taattggtcc
     2041 agggatattc atggtgaccg ataataagct accttctggg tactccttta ataaatgcag
     2101 ctgacgcaga gctctttctt cgcgggctct taacatatca ctaagttgga tagattcacc
     2161 tgaaaaataa gcttctttag acattgtaaa ccacatcaat gaggctacca tcacggtatt
     2221 caataagagc aacaacctta tcaccatatt gaatacgctc aggtgtgcca acgatagcat
     2281 aagccttctc ttttagctcc tcaatactaa attgtggtac attaagggat ttgaaatggt
     2341 ctactaagtc ttgacgattt gggttaatgg caattcccac ttctgtgacg accacatcga
     2401 cacttgttcc tggtgtaatg accgtattaa cctcatctac aaaagttggg atgcgtccgc
     2461 ggataagtgg tgaaataacc aaactcatct tagccgcaaa ggcagtgtcg cagtgtcctc
     2521 cagaagcgcc acgaatcacg ccgtcagatc ctgtcatcac attaacattg aagttagtat
     2581 caacttcaag ggctgataaa atacaagtgt ctaattgatt gataacagca cccttgctca
     2641 aaggtgaggc atacatgttg gcatcaattt cataatgttc agcatgctta ccaagagaaa
     2701 cagctgatgg gtgatcaaag tcttggacat caagaatttt ttcaaccagt ccttcttcga
     2761 gcaactccac catagcattg gtaataccac caagagcaaa gctagctttg atattttctt
     2821 taatcatagc ttcacgcatg aaacgggtta ctgccaaaga agcgccacct gttccagttt
     2881 ggaaagagaa tccttcttta aaataaggag agttggtgat tactttagcg gcgtattctg
     2941 caattaagag ttctttagga tttttcgtaa aacgagttgc ccctttggcg attccttgag
     3001 gatctccgat agcatccact gttaccacat agtcaacatc tgtttgagga atgctgattg
     3061 gggtattagg ataaggaacc aaattatctg tcaagataac cacctgatcc gcatatttgg
     3121 catcaatcat ggcatagccc aaagaaccac aggttgcttt cccttttgtc ccattaacat
     3181 ttccgtaagc atctgaactt ggggcgccca gaaaggcaac atcaatatgg atatccccac
     3241 tagcaatggc acgagcgcg
//
LOCUS       DAXMQE010000071         2948 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.071, whole genome shotgun sequence.
ACCESSION   DAXMQE010000071 DAXMQE010000000
VERSION     DAXMQE010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2948)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2948)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2948
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.071"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            <1..534
                     /locus_tag="ACF4ZO_001863"
     CDS             <1..534
                     /locus_tag="ACF4ZO_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HFD5487362.1"
                     /translation="PRAGAIFVMVTYAHGYGHTGLVIVTSDGYVLHNIEQNVDGNADA
                     LYIGGPARYVDRPFEDGTGYILGWFYPPYDSTPAAVTEPSAPVVAQSDGTYVANPETG
                     TFTVRVAALNVRSAPRLDAEIVATYGENMEFNYDGWIDSDGYIWVTYISVTGVRRYVS
                     VGNSENGRRVTNFGTFR"
     gene            complement(603..1310)
                     /gene="speC"
                     /locus_tag="ACF4ZO_001864"
     CDS             complement(603..1310)
                     /gene="speC"
                     /locus_tag="ACF4ZO_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021733756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptococcal pyrogenic exotoxin SpeC"
                     /protein_id="HFD5487363.1"
                     /translation="MKKINIIKIVFIITVILISTISPIIKSDSKKDISNVKSDLLYAY
                     TITPYDYKDCRVNFSTTHTLNIDTQKYRGKDYYISSEMSYEASQKFKRDDHVDVFGLF
                     YILNSHTGEYIYGGITPAQNNKVNHKLLGNLFISGESQQNLNNKIILEKDIVTFQEID
                     FKIRKYLMDNYKIYDATSPYVSGRIEIGTKDGKHEQIDLFDSPNEGTRSDIFAKYKDN
                     RIINMKNFSHFDIYLEK"
     gene            complement(1421..2179)
                     /gene="mf2"
                     /locus_tag="ACF4ZO_001865"
     CDS             complement(1421..2179)
                     /gene="mf2"
                     /locus_tag="ACF4ZO_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNase Mf2"
                     /protein_id="HFD5487364.1"
                     /translation="MKLSKQKASLLTAVLLLLSLSITTITVDAAKVRTYPNVSHANTH
                     YKNTASSKLLPFTANYQLQLGELDNLNRATFSHIQLQDRHETKDVRTKINYDPVGWHN
                     YQFPYGDGSKSSWVMNRGHLVGYQFCGLNDEPRNLVTMTAWLNTGAYSGANDSNPEGM
                     LYYENRLDSWLALHPDFWLDYKVTPIYSGNEVVPRQIELQYVGIDSSGELLTIRLNSN
                     KESIDENGVTTVILENSAPNINLDYLNGTATPKN"
     gene            2419..2601
                     /locus_tag="ACF4ZO_001866"
     CDS             2419..2601
                     /locus_tag="ACF4ZO_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Paratox"
                     /protein_id="HFD5487365.1"
                     /translation="MLTYDEFKQAIDNGYITADTVMIVRKNGQIFDYVLPNEKIKNGE
                     IVTDEKVEEVLVELSR"
BASE COUNT          917 a          451 c          542 g         1038 t
ORIGIN      
        1 ccacgagctg gggctatctt tgtgatggtg acctatgctc atggttacgg tcatactgga
       61 ttagttattg tgacgtcaga cggatatgtt ttgcataaca tcgagcaaaa cgtggatggt
      121 aatgctgacg ccctttacat cggtggtcca gctcgatatg ttgaccgccc atttgaagat
      181 ggcactggat atattttggg ttggttttac cctccttacg atagtacgcc agcagcagtg
      241 acagagccaa gcgctccagt ggttgcacag tcagatggta cttatgtagc taaccctgaa
      301 acaggtactt ttactgttcg tgttgctgct ttaaacgtcc gttctgcgcc tcgattagac
      361 gcagaaattg tggcaactta tggcgaaaac atggaattta actatgatgg ttggattgac
      421 tcagatggtt atatttgggt gacatacatc agtgttactg gtgttagacg atatgtgtcc
      481 gtcggaaatt ccgaaaacgg acgacgtgtg accaactttg gtacttttag ataggaggta
      541 aagctccgag ataagacaaa accgctcaga taatttctgg gcggtttttt gtgtatgatg
      601 aattattttt caagataaat atcgaaatga ctaaagttct tcatattgat aattctatta
      661 tctttatatt ttgcaaaaat atctgatcta gtcccttcat ttggtgagtc aaataagtct
      721 atttgctcat gtttcccatc ttttgtgcca atttcgattc tgccgcttac ataaggagaa
      781 gtagcgtcat aaattttata attatccata aggtattttc tgattttaaa gtcaatttcc
      841 tggaaagtta cgatatcttt ttctagaata attttgttat ttaagttctg ttgagattct
      901 cccgaaataa atagatttcc caataattta tgatttactt tattattttg agcaggcgta
      961 attcctccat agatgtactc accggtgtga gaattaagaa tataaaataa tccaaaaaca
     1021 tctacatgat catctcgttt aaatttttga gaggcctcat aagacatttc ggaactaata
     1081 taatagtctt tccctctata tttttgagta tcaatgttta atgtgtgtgt cgttgaaaaa
     1141 tttaccctgc aatctttata atcataagga gttatagtgt atgcataaag taaatcactt
     1201 ttaacattcg aaatgtcttt cttagagtca cttttgatga taggtgaaat agtagaaatc
     1261 agtatgactg taattatgaa aactattttg atgatgttaa tctttttcat tttttctcct
     1321 taattaaatg tattactcgt acgagaatac atgaaatagc agtaagtagt taaaaatcag
     1381 atttctgttt atttagaaat tttataaatg tatttatatt ttagttttta ggagtggcag
     1441 ttccatttaa atagtcaagg ttgatatttg gagcagagtt ttctaagatt actgtagtaa
     1501 caccattttc atcaatactt tctttattac tatttagcct tatagtaagc aactcaccag
     1561 atgaatcaat tccaacatac tgtaattcaa tttgtcgagg cactacttca ttgccactat
     1621 atataggagt gactttataa tctagccaaa agtcagggtg aagtgcaagc caagaatcta
     1681 aacggttttc atagtataac atcccttcag gattgctgtc atttgctcct gaataagcac
     1741 ctgtgtttag ccaggctgtc attgtcacta aatttcttgg ttcatcgttt aatccacaaa
     1801 attgatatcc gactagatgc ccacgattca ttacccatga agattttgag ccatctccgt
     1861 atggaaattg atagttatgc catcccacag ggtcataatt tattttagtg cgtacatctt
     1921 tagtttcgtg tctatcttgc agttggatat gtgaaaaggt agcgcggtta aggttatcca
     1981 actcaccaag ttgtaactga taattagcag taaaaggtaa gagcttacta gaagcagtat
     2041 ttttataatg tgtgtttgca tgggatacat tcggataagt tcgtacctta gctgcgtcaa
     2101 cagttattgt cgttatagaa agagaaagta acagtaaaac agcggtaagc aaacttgcct
     2161 tttgtttaga taatttcatg ataacaccta aacctttcca tttttagctt ttagagtgga
     2221 tcaaatattg cacttttcta gttaattata tcactttaaa ttaaaaaaac ttaaaattaa
     2281 taaaattaat ttatcaataa tattacgcta aaatttcttt ttgtttaata aaatagaagt
     2341 tattaaattt taataagttt taaatttaag tgtactatat tctcgtaaaa tacgaataat
     2401 aagataagga ggtgctttat gctaacatac gacgaattta aacaagcaat tgacaatgga
     2461 tatatcacag cagacacagt aatgatcgtg cgcaagaacg gacagatttt tgattatgtg
     2521 ttgccgaatg agaagataaa gaatggagaa attgtgacag acgaaaaagt ggaagaggtg
     2581 ctggtggagc tttcgagata agtattttct ttgccctctg agaagtagtt ttattaaagg
     2641 ggtaaatagg gggcataagt ttaaaactta catagttgat tcgaagcaat tatataaagt
     2701 ttcgttattt tgtagcttta taaaatcaaa gtttattata ttatatgtgc acaatattaa
     2761 gtaatcttta aaagacgctg ttaaataatt cgtctagaaa aatcttgttg ctatcgatgt
     2821 ttattgatag cgacaaggtt ctttttttat atttggggca taaagttagt agttttctct
     2881 tcagttaagc caagttctaa agcatgcact ctataatggt cagtcatcct tctattagta
     2941 tatcattt
//
LOCUS       DAXMQE010000072         2929 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.072, whole genome shotgun sequence.
ACCESSION   DAXMQE010000072 DAXMQE010000000
VERSION     DAXMQE010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2929)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2929)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2929
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.072"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            <1..679
                     /locus_tag="ACF4ZO_001867"
     CDS             <1..679
                     /locus_tag="ACF4ZO_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="arginine deiminase family protein"
                     /protein_id="HFD5487366.1"
                     /translation="RETLYGKYIFTHHPIYGGGKVPMVYDRNETTRIEGGDELVLSKD
                     VLAVGISQRTDAASIEKLLVNIFKQNLGFKKVLAFEFANNRKFMHLDTVFTMVDYDKF
                     TIHPEIEGDLRVYSVTYDNEELHIVEEKGDLAELLAANLGVEKVDLIRCGGDNLVAAG
                     REQWNDGSNTLTIAPGVVVVYNRNTITNAILESKGLKLIKIHGSELVRGRGGPRCMSM
                     PFEREDI"
     gene            779..1219
                     /locus_tag="ACF4ZO_001868"
     CDS             779..1219
                     /locus_tag="ACF4ZO_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009881066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFD5487367.1"
                     /translation="MTDKFDANDETRTVYAVVYDNDQPVSTGQFLAETKIEARLTRIV
                     TLADYCGCGYGAKVTEALETYTRREGFYQLTIHSELTAQTFYENLGYQTYGSKYLEDG
                     EYCQSLVKTILKWEKNMDIAMLIAIVGGLLGCYLYLTKNNEPKD"
     gene            1244..2257
                     /gene="argF"
                     /locus_tag="ACF4ZO_001869"
     CDS             1244..2257
                     /gene="argF"
                     /locus_tag="ACF4ZO_001869"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000195397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004585 - ornithine carbamoyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0042450 - arginine biosynthetic process via
                     ornithine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HFD5487368.1"
                     /translation="MTQVFQGRSFLAEKDFTRAELEYLIDFSAHLKDLKKRGVPHHYL
                     EGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRMF
                     DGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVKENFGKLEGLTLVY
                     CGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEEEIVTLAEGYAKESGARILITEDA
                     DEAVKGADVLYTDVWVSMGEEDKFKERVELLQPYQVNMDLVQKAGNDKLIFLHCLPAF
                     HDTNTVYGKDVAEKFGVKEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLFI
                     PKV"
     gene            2427..>2929
                     /locus_tag="ACF4ZO_001870"
     CDS             2427..>2929
                     /locus_tag="ACF4ZO_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HFD5487369.1"
                     /translation="MTEEKKRGFRIPSSYTVLFIIIAIMAVLTWFIPAGAYETAKGGG
                     VISGTYKTVASNPQGFFDILMAPVRGMLGVEGTDGAIQVSFFILMVGGFLGVVNKTGA
                     LDTGIASVVRKNKGREKMLIAILIPLFALGGTTYGMGEETMAFYPLLIPVMIAVGFDS
                     IVAVAII"
BASE COUNT          872 a          554 c          623 g          880 t
ORIGIN      
        1 ccgtgaaacc ctttatggta aatacatttt cactcatcac ccaatttatg ggggtggcaa
       61 agtgcctatg gtttatgacc gtaatgaaac cactcgcatt gaaggtgggg acgaacttgt
      121 tctttcaaaa gatgtgcttg cggttggtat ttctcaacgt acagatgctg cttctattga
      181 aaaattgttg gttaacatct ttaaacaaaa ccttggcttc aagaaagtat tggcctttga
      241 atttgcaaat aaccgtaaat ttatgcactt agacactgtc tttaccatgg ttgactatga
      301 caaatttacc attcacccag aaattgaagg agaccttcgt gtttactctg tcacttacga
      361 caatgaagaa cttcatatcg ttgaagaaaa aggtgattta gcagaacttc ttgctgctaa
      421 ccttggtgtt gaaaaagttg accttatccg ttgtggtggt gacaacttag tagcagcagg
      481 tcgtgaacaa tggaacgatg gttctaacac ccttactatc gcaccaggtg tggttgtggt
      541 ttataaccgt aacaccatta ccaatgctat tcttgaatct aaaggcttga aattgatcaa
      601 gattcacgga agtgaattgg ttcgcggtcg tggtggacct cgttgtatgt caatgccatt
      661 tgaacgtgaa gatatttaat aagctatggt aaaggtggtt ataggtcaga agtcttttta
      721 aagggcagct agtgtttatc ttcgcttctg tgtctttgtc cttcaatgaa attttgtcat
      781 gacagataaa tttgatgcca atgacgaaac aagaacggtt tatgcagtcg tttatgacaa
      841 tgaccagccc gtttcaacag gacaattttt agctgaaacg aaaatagaag cacgattgac
      901 acgcattgta accttagcag attattgtgg ttgcggttat ggtgccaaag tcactgaagc
      961 gctagaaact tataccagac gagaaggctt ttaccaacta accattcaca gtgaactgac
     1021 agcacaaacc ttttatgaaa acctaggtta tcagacctat ggttccaagt atttagaaga
     1081 tggtgagtat tgtcaatccc ttgttaaaac cattcttaaa tgggagaaga atatggacat
     1141 agcaatgcta attgcgattg ttggtggtct attaggctgc tatctctatc tcacaaaaaa
     1201 taatgaaccc aaagattaag ttaatactcg aaggagacaa tagatgacac aagtatttca
     1261 aggacgtagc ttcctagcag aaaaagattt tacacgcgct gaattagaat accttattga
     1321 tttttcagct catttgaaag atttgaaaaa acgtggtgtg cctcatcact acttagaagg
     1381 taaaaacatt gccctcttgt ttgaaaaaac atcaactcgt acgcgtgcag cttttacaac
     1441 agcagccatt gacctaggtg ctcacccaga atacctcggt gccaatgaca tccaacttgg
     1501 taaaaaagaa tcaacagaag acactgctaa agtattgggt cgtatgtttg atgggattga
     1561 attccgtggc tttagccaac gcatggttga agaattggca gaattctcag gtgtgccagt
     1621 ttggaatggt ttgactgatg aatggcaccc aacccaaatg cttgctgact atttaacagt
     1681 gaaagaaaac tttggcaaac ttgaaggcct tacccttgtt tactgtggtg acgggcgtaa
     1741 taacgttgcc aattcccttc ttgtgactgg tgctatcctt ggtgttaatg ttcatatctt
     1801 ctcaccaaaa gaactcttcc cagaagaaga gattgtgaca ttggctgaag gctatgctaa
     1861 agaaagtggc gctcgtatcc ttatcacaga agatgctgac gaagctgtta aaggcgcaga
     1921 cgtgctttac acagatgttt gggtatcaat gggtgaagaa gacaaattca aagaacgtgt
     1981 tgaattgctt caaccatatc aagtcaacat ggaccttgtt caaaaagcag gaaatgacaa
     2041 gcttatcttc ttgcactgct tgccagcttt ccatgacaca aacaccgttt atggtaaaga
     2101 cgttgctgaa aaattcggcg tgaaagaaat ggaagtcact gatgaagtct tccgcagcaa
     2161 atacgctcgt cattttgatc aagctgaaaa ccgtatgcac actatcaaag cggttatggc
     2221 agcaaccctt ggtaacctct ttattccaaa agtgtaataa ggactggtac tccttaactc
     2281 atttcacata tcaatgtgat ccctttaatt taacaattta actacttaaa aacgtacttt
     2341 aactacatga caagtcgttc tggttctcgt gtccttgacc ggaactagaa cggcttattt
     2401 ttatgaaaag gtaagaggta atcattatga cagaagaaaa aaaacggggt tttagaattc
     2461 cttcttctta caccgttctt tttatcatta tagccatcat ggcagtgtta acttggttta
     2521 ttccagctgg cgcctacgaa accgctaagg gcggtggtgt tatttcagga acctacaaaa
     2581 cagtagcatc caatcctcaa ggattttttg acatcttgat ggctcccgtt cgaggcatgt
     2641 taggtgttga aggcactgat ggtgctattc aagtgtcttt ctttatctta atggttgggg
     2701 gctttttagg agttgtcaac aaaacaggtg ctcttgacac aggaatagcg tcagtggttc
     2761 gtaaaaacaa aggtagagaa aaaatgctga ttgctatttt aatccctttg tttgctctag
     2821 gtggaacgac ctatggtatg ggggaagaaa ccatggcctt ttacccactt ttaattcctg
     2881 ttatgattgc ggttggtttt gacagtattg ttgctgtagc cattatttt
//
LOCUS       DAXMQE010000073         2879 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.073, whole genome shotgun sequence.
ACCESSION   DAXMQE010000073 DAXMQE010000000
VERSION     DAXMQE010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2879)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2879)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2879
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.073"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            175..1989
                     /gene="glmS"
                     /locus_tag="ACF4ZO_001871"
     CDS             175..1989
                     /gene="glmS"
                     /locus_tag="ACF4ZO_001871"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019804802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004360 - glutamine-fructose-6-phosphate
                     transaminase (isomerizing) activity [Evidence IEA];
                     GO_process: GO:1901137 - carbohydrate derivative
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HFD5487370.1"
                     /translation="MCGIVGVVGNRNATDILMQGLEKLEYRGYDSAGIFVANGDKLSL
                     VKSVGRIADLRSKIGIDVAGSTGIGHTRWATHGQATVENAHPHTSASSRFVLVHNGVI
                     ENYLQMKEEYLAGHEFKGQTDTEIAVHLIGKFVEEDGLSVLEAFKNALSIIEGSYAFA
                     LIDTEDADTIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETSQFMEIHDKELVILTKD
                     SVTVLDYDGNQLERDSYTAELDLSDIGKGTYPFYMLKEIDEQPTVMRKLISTYSDESG
                     KMAIDPAIVKTIQEADRIYILAAGTSYNAGFASKAMIEQLTDTPVELGVASEWGYNMP
                     LLSQKPMFILLSQSGETADSRQVLVKANQMGIPSLTVTNVPGSTLSREATYTMLLHAG
                     PEIAVASTKAYTAQVAALAFLSKAVGEANGKKEALEFDLVHELSLVAQSIEATLSEKD
                     LIASKVEKLLATTRNAFYIGRGNDYYVAMEASLKLKEISYIQCEGFAAGELKHGTISL
                     IEDGTPVIGLISSSELVAAHTRGNIQEVAARGASVLTVVEEGLDREGDDIVVNKVHPY
                     LATIGMVIPTQLIAYYASLQRGLDVDKPRNLAKAVTVE"
     gene            2112..>2879
                     /locus_tag="ACF4ZO_001872"
     CDS             2112..>2879
                     /locus_tag="ACF4ZO_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFD5487371.1"
                     /translation="MEQKSSLKVKVQKLGTALSNMVMPNIGAFIAWGVLTALFIPTGW
                     LPNAEFAKAVGPAITYLLPLLIGYTGGYVVHGQRGAVVGAIATFGAVAGSEVPMFIGA
                     MAMGPLGGWAIKKFDQAFQEKIRPGFEMLVNNFSAGLIGFGLLLLAFKLVGPFVAIFT
                     TAIGNGVQAIVDMKLLPLANILIEPAKILFLNNALNHGIFTPLGAEQVAKTGKSILFL
                     LEANPGPGFGILLAYMVFGKGAAKSSSWGALIIHFLGG"
BASE COUNT          893 a          467 c          582 g          937 t
ORIGIN      
        1 atgagtagtc agttgactac tcatttttaa aattagacta taccaataaa atgtttgaca
       61 agataaaata ggtggtatat acttaaaaca tagctttttg ggtagtttta tttgactata
      121 ccaatttaat taataagaaa aggtagtaag ttattcttac taaggtaaat aataatgtgt
      181 ggtattgttg gagtcgtagg aaatcgaaat gcgactgata ttttgatgca aggtttagag
      241 aaattagaat accgtggtta tgattcagct ggtatttttg ttgccaatgg tgacaagtta
      301 agtctagtta agtctgtagg aagaattgca gatttgcgtt caaaaattgg tattgatgta
      361 gctggtagta caggtattgg acatacacgt tgggcaactc atggacaagc aaccgttgaa
      421 aatgctcacc cacatacttc tgcatcaagc cgctttgtac tcgttcataa tggtgttatc
      481 gagaactatc ttcaaatgaa agaagagtat ttagcaggcc atgaatttaa aggtcaaaca
      541 gatactgaaa tcgctgttca tttaattggt aaatttgtag aagaagatgg tttatcagta
      601 ctggaagcat ttaaaaatgc actttcaatt attgaaggtt catatgcttt tgccctgatt
      661 gatacagagg atgctgatac aatctatgtt gcaaaaaata aatctccatt gctcattggt
      721 ttaggcgaag gctataatat ggtatgttct gatgcgatgg ctatgattcg tgaaaccagc
      781 caatttatgg aaattcatga taaagaactt gttatcttga caaaagattc agtgactgtt
      841 ttagattatg atggtaacca acttgaaaga gattcatata cagcagaatt agacttatct
      901 gacattggaa aaggaactta tcctttctac atgttaaaag aaattgatga gcaacctact
      961 gttatgcgta aattgatttc aacttattct gatgaatctg gaaaaatggc aattgaccct
     1021 gccattgtca aaactattca agaagcagat cgtatttaca tcttagctgc aggtacatct
     1081 tacaacgctg gttttgcttc aaaagcaatg attgaacaat taacagatac acctgttgaa
     1141 cttggtgttg cttctgagtg ggggtataat atgccactct taagtcaaaa accaatgttt
     1201 atcttgttga gtcaatcagg tgaaactgct gatagtcgac aagttttggt taaagctaac
     1261 caaatgggga tcccaagttt aacggttaca aacgtaccag gttcaacact gtcacgtgaa
     1321 gctacctaca ccatgttact acatgctgga ccagaaattg cagttgcttc aacaaaagcc
     1381 tatactgctc aggttgcagc acttgctttc ttatcaaaag cagttggtga agcaaatggt
     1441 aaaaaagaag ctttagagtt tgacttagtc catgaacttt ctctagtcgc tcaatctatt
     1501 gaagcaaccc tttctgaaaa agatttaatt gcatcaaaag ttgagaaatt attagcgaca
     1561 acccgcaatg ctttctatat tggtcgtggt aatgattatt atgttgccat ggaagcttct
     1621 ttgaaattaa aagaaatttc atacattcaa tgtgaagggt ttgcagctgg tgaattaaaa
     1681 catggtacaa tttctctcat tgaagatggc acacctgtta tcggcttgat ttcttcaagt
     1741 gaacttgttg cagctcatac tcgtggaaat atccaagaag tagcagcacg tggagctagt
     1801 gtcttaactg ttgttgaaga aggtttggac cgtgaaggtg atgacattgt tgtcaataaa
     1861 gtacatccat atttagcaac tattggaatg gtcattccga cacaacttat tgcttactat
     1921 gcatcattac aacgtggcct tgatgttgac aaaccacgta atttagcaaa agccgttact
     1981 gtagaataat agatttaaaa ggcatctttc agatgtcttt tttgtgtcac agcttttgtg
     2041 ccaaagtttg agttctgatg tcagcgtttc catgataaga taaaattgta aataatttag
     2101 gaggcgttct aatggaacaa aaatcttcac ttaaagttaa agtccaaaaa ttaggtacag
     2161 cattatcaaa tatggttatg cctaacattg gtgcatttat tgcctggggt gttttaacag
     2221 ccttatttat tccaacaggt tggttaccaa atgcagaatt tgcaaaagcg gtaggtcctg
     2281 caatcactta tttgctacca ctattaattg gttacactgg tggttatgtt gttcatggac
     2341 aacgcggagc agtagttggt gcaatcgcaa ccttcggtgc agttgctggt tctgaagtac
     2401 caatgtttat cggtgcaatg gcaatgggac cacttggtgg ttgggcaatt aaaaaatttg
     2461 accaagcttt ccaagaaaaa attcgtccag gttttgaaat gttagtaaac aatttctcag
     2521 ctggattaat tggatttggt ttactcttgt tagcctttaa attagttggt ccatttgtgg
     2581 caatctttac aacagctatt ggtaatggtg tacaagctat cgttgatatg aaattattac
     2641 cgttagctaa tatcctaatt gaaccagcta agattctttt ccttaataac gctctaaacc
     2701 atggtatttt tacaccactt ggagctgaac aagttgctaa aacaggaaaa tcaattcttt
     2761 tcttattaga agctaaccct gggccaggtt ttggtatttt actggcttac atggtctttg
     2821 gtaaaggtgc tgctaaatct tcttcatggg gtgcattaat cattcacttc cttggaggt
//
LOCUS       DAXMQE010000074         2836 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.074, whole genome shotgun sequence.
ACCESSION   DAXMQE010000074 DAXMQE010000000
VERSION     DAXMQE010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2836)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2836)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2836
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.074"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            177..953
                     /gene="recX"
                     /locus_tag="ACF4ZO_001873"
     CDS             177..953
                     /gene="recX"
                     /locus_tag="ACF4ZO_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006282 - regulation of DNA repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HFD5487372.1"
                     /translation="MKITKIEKKKRLYLIELDNDDSLYVTEDTIVRFMLSKDKVLDND
                     QLEDMKHFAQLSYGKNLALYFLSFQQRSNKQVADYLRKHEIEEHIIPDIITQLQEEQW
                     IDDTKLADTYIRQNQLNGDKGPQVLKQKLLQKGIASHDIDPILSQTDFSQLAQKVSQK
                     LFDKYQEKLPPKALKDKITQALLTKGFSYDLAKRSLNHLNFDQDNQEIEDLLDKELDK
                     QYRKLSRKYDGYTLKQKLYQALYRKGYNSDDINCKLRNYL"
     gene            1033..1566
                     /locus_tag="ACF4ZO_001874"
     CDS             1033..1566
                     /locus_tag="ACF4ZO_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002949762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HFD5487373.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENALIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGVSYYCNLASPYMMDTEALKYI
                     DYDLDVKVFADGEKRLLDVDEYEIHKKEMQYSADMDFILKENVKILVDWINHEKGPFS
                     KAYITIWYKRYLELKNR"
     gene            2044..2350
                     /locus_tag="ACF4ZO_001875"
                     /pseudo
     CDS             2044..2350
                     /locus_tag="ACF4ZO_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935295.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(2636..2707)
                     /locus_tag="ACF4ZO_001876"
     tRNA            complement(2636..2707)
                     /locus_tag="ACF4ZO_001876"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2672..2674),aa:Glu,seq:ttc)
     gene            complement(2730..2803)
                     /locus_tag="ACF4ZO_001877"
     tRNA            complement(2730..2803)
                     /locus_tag="ACF4ZO_001877"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2767..2769),aa:Ile,seq:gat)
BASE COUNT         1004 a          535 c          484 g          813 t
ORIGIN      
        1 cagcagcttt tatgggcagc ataaaataaa aattccccga catagtcccc gacaaaatat
       61 tactttttat gatttttgtt actttttatg gctaaacaaa aaaactaaaa cgctgtaata
      121 tcaatgtttt aaaacaattt gcttgtatat aaattttaaa atactataat gaacatatga
      181 aaatcactaa aattgaaaag aaaaaacgcc tctaccttat cgaattggat aatgacgatt
      241 ccctttatgt aacagaagat actattgttc ggtttatgtt gagtaaagat aaagtccttg
      301 acaatgatca gcttgaagac atgaaacatt ttgcccaact gtcctacggc aaaaatttag
      361 ccctttattt tctttccttt caacaacgca gcaacaagca agttgctgat tacctgcgca
      421 agcatgagat tgaagaacac attattcctg acatcatcac tcaactccaa gaagaacaat
      481 ggatagacga caccaaattg gctgatacct acattcgcca aaatcagtta aatggtgata
      541 aaggtcccca agtcttaaaa caaaaattat tacaaaaagg cattgcaagt catgacattg
      601 atcctatctt atctcaaact gactttagcc aactcgctca aaaagtaagc caaaaactct
      661 ttgacaaata tcaagaaaaa ttgccaccaa aagccttgaa agataaaatc acccaagcat
      721 tactgactaa aggcttttca tacgacctag ctaaacgtag cctcaatcac cttaattttg
      781 accaagataa tcaagaaata gaagatcttc ttgacaaaga attagacaaa caatatcgta
      841 aactcagtcg caaatatgat ggttatacct taaagcaaaa gctctatcag gctctctacc
      901 gaaaaggcta caacagcgac gatattaatt gcaagttaag aaattattta tagactgaca
      961 aaagaagtga ttttttcaca catttatgat agactataga ggataagttt aattgtagaa
     1021 agttggtaag gcatgaaatt acctaaagaa ggcgacttta ttacaattca aagttataag
     1081 catgatggta gtttgcaccg tacttggcgc gatactatgg tactaaaaac aactgaaaat
     1141 gccctcattg gagttaatga tcacactctt gtcacagaaa gtgacggtag acgatgggtg
     1201 acccgcgaac ccgcaatcgt ttactttcat aaaaaatact ggtttaacat tatagccatg
     1261 attcgagata atggcgtctc ttattactgt aacttagcta gtccatatat gatggacact
     1321 gaggccctca aatacattga ttacgattta gatgtcaaag tctttgcgga tggtgaaaag
     1381 agattacttg atgttgatga atacgagatt cataaaaaag agatgcagta ttcagccgat
     1441 atggacttta tcctaaaaga aaatgtcaaa atattggttg attggattaa tcatgaaaaa
     1501 ggaccatttt ccaaggccta tatcactatt tggtacaaac gttatcttga actgaagaat
     1561 cgttaagagt tgtccagcac tcccaaggag tgctcagaac gcagacaaac tcagttttag
     1621 gctcaaaaag catgaacagc tctgctgatt tgacatccaa tttcctattt ctgcgtgtgg
     1681 agtgagccaa aacagatgtt tttcgttgtg gtaaaagtgg tgtcaatgtt agtgttgacg
     1741 ccacttggta tttttgagcc taggatctca aaaataaggc atggaattcc aaaggaagtc
     1801 gctgccttaa gcactaccta aggaaagtat caaaaaatac taagtttagt agcgaggaaa
     1861 tctccgacga aagagagtac ccactacttt ttctttgcgt taaagtagaa gtgtcttgtt
     1921 aagtcgcaaa gtcttttggc acttgatgtt gtaaccaaaa ctgacaagac acctctttta
     1981 ggtagaattt tatcaaagta tgtaggacgc ttgacgtcgt gtattgaaaa tgaaaccact
     2041 acaataagga atcattcaag acaaaacgat accatcggcc tcaatcgtct tcttggaaac
     2101 ttgaaaaccg tccataaccc tgagattatc cttaaaacga ttaatgtcta ttctcgtcgt
     2161 cttcaggttt tttcgcagat aatggctacg cttatactcg gtttaatcct ttagaagcta
     2221 agaagcaatt gaatagcctg cacgttcgta aaacagacaa aattgacact gagaagaagt
     2281 ctaataaaat ctgacagaag atattgtggg agttaagaat cgtctgcata agcttttcca
     2341 agtcaccttt tgtcttacta taactgctaa aattaccatt aaaaccacat taagatctcc
     2401 atactatcca ttaattaaac aatttctttt ataatgggat ttgtaatata tgcatacaac
     2461 ctacaacaac acatgacttg agagcattgt aaagtgtctt ttaaacccca atctgcaatt
     2521 aaaaataaac aataaaaagc ttaaatttgt tatataacaa atttaagctt tttattgtta
     2581 aaatacaatc aaccaagtta gttcgattat tttaaccaaa gttactaaat agctatagtc
     2641 cgtacgggat tcgaacccgt gttaccgccg tgaaaaggcg gtgtcttaac cccttgacca
     2701 acggaccata ataatataat tatagataat gggcacgagt ggactcgaac caccgacctc
     2761 acgcttatca ggcgtgcgct ctaaccacct gagctacgcg cccaagctaa tagcttggaa
     2821 aaattattac tattgg
//
LOCUS       DAXMQE010000075         2722 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.075, whole genome shotgun sequence.
ACCESSION   DAXMQE010000075 DAXMQE010000000
VERSION     DAXMQE010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2722)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2722)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2722
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.075"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            11..265
                     /locus_tag="ACF4ZO_001878"
     CDS             11..265
                     /locus_tag="ACF4ZO_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008088460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5487374.1"
                     /translation="MVGIRINGELVTFDSNFRDALIFTIDCLRGSEEPTLKQTYQTFK
                     DYTDEDLMDYIETEFDVWPELIVNRKIDSKWSTKQHILDD"
     gene            287..769
                     /locus_tag="ACF4ZO_001879"
     CDS             287..769
                     /locus_tag="ACF4ZO_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000323862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siphovirus Gp157 family protein"
                     /protein_id="HFD5487375.1"
                     /translation="MAYLYELEGIAAYLESLDLDDETFQNTLDSIDFQSDLENTIEYF
                     VKMLKNAQADVEMYKAEKEAFYKKQKQAEAKVEKYKETIRRAMELSQKKKVDAGMFKV
                     SLRKSKKVEILDETKIPLDYMQEKIEYKPMKSEISKALKSGIDISGVELIETESLQVK
                     "
     gene            770..1444
                     /locus_tag="ACF4ZO_001880"
     CDS             770..1444
                     /locus_tag="ACF4ZO_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ERF family protein"
                     /protein_id="HFD5487376.1"
                     /translation="MRKSESITEYAKAFCKAQLEVKQPLKDKDNPFFKSKYVPLENVT
                     EAITKAFANNGISFSQDPTTNTENGYIDVATLVMHTSGEWVEYGPLSVKPTKNDVQGA
                     GSAITYAKRYALSAIFGITSDQDDDGNEASKPNKTNQSQKPTNKTSKGASFQTPKISN
                     IQVETYKSDLSDIAKATNQNVEELTKWLTDTLKVKSLEDLRTEQIVSTDDLINKLKKR
                     AGQKND"
     gene            1437..1856
                     /gene="ssb"
                     /locus_tag="ACF4ZO_001881"
     CDS             1437..1856
                     /gene="ssb"
                     /locus_tag="ACF4ZO_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HFD5487377.1"
                     /translation="MINNIVLVGRMTKDAELRYTASQVAVATFTLAVNRRFKEQNGER
                     EADFINCVIWRQSAENLANWAKKGALIGITGRIQTRNYENQQGQRVYVTEVVAESFQM
                     LESCNQQSGQGNSSQNDNSQPFGNSNPMDISDDDLPF"
     gene            1862..2065
                     /locus_tag="ACF4ZO_001882"
     CDS             1862..2065
                     /locus_tag="ACF4ZO_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5487378.1"
                     /translation="MANRYRQRIYAVYDGDSFVDVGTKHELAERLGVTADTIVFIASP
                     AHKKRRPDGRHAEFIGYEDELEE"
     gene            2065..2505
                     /locus_tag="ACF4ZO_001883"
     CDS             2065..2505
                     /locus_tag="ACF4ZO_001883"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0000400 - four-way junction DNA binding
                     [Evidence IEA];
                     GO_function: GO:0008821 - crossover junction DNA
                     endonuclease activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HFD5487379.1"
                     /translation="MVKFIIPIEPKPQKRPRFSRWSGAYEDGDMMAWRKQVTDYVKNN
                     YEGPYFDDGLKVDVTFYLKAPELVSKKPSERAKDKTKQKYQDYINELLYVPKKPDLDN
                     LEKAVYDSISKSEVVWTDDNIIVEHTTRKLYSPNPRIEVKINEL"
     gene            2502..>2722
                     /locus_tag="ACF4ZO_001884"
     CDS             2502..>2722
                     /locus_tag="ACF4ZO_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5487380.1"
                     /translation="MTLVDDFYKQMEPSIKAFLDDNITIADKEEADRVYRSVKCYKKL
                     NRLPPPDVLEWFQRIYTTEEMIMLIKQSYR"
BASE COUNT         1025 a          481 c          582 g          634 t
ORIGIN      
        1 gaggtgcgaa atggttggaa tcagaattaa cggtgagctc gtaacctttg atagcaattt
       61 tagagatgcg cttatcttta cgattgactg tcttagaggc agcgaagaac ctacgctaaa
      121 acagacttat caaaccttta aagactacac agacgaagac ttgatggact acatcgagac
      181 ggaatttgat gtatggccag agctaatcgt taatcgcaag attgacagca agtggtccac
      241 taaacaacac attttggatg attaaaatac agaaagagga aataacatgg cttatttata
      301 tgaacttgag ggaatcgccg cttatctgga aagtttagat ttagacgacg aaacctttca
      361 aaatacgctt gacagcattg attttcaatc agacttagaa aataccattg agtattttgt
      421 caaaatgtta aaaaatgctc aagctgacgt cgaaatgtat aaagccgaaa aagaagcttt
      481 ttacaaaaag caaaagcaag cagaagcaaa agtggaaaaa tacaaagaga caatcaggcg
      541 tgcaatggaa ttgagccaaa agaaaaaagt tgacgctgga atgtttaagg tgtctttgcg
      601 aaaaagcaaa aaagtagaga ttttggacga aacaaaaatt cctcttgatt acatgcaaga
      661 aaaaattgaa tacaaaccaa tgaaatctga gatctcgaaa gctttgaaat ctggaattga
      721 tatatctgga gttgaactaa tcgaaacaga aagtttgcag gtaaagtaaa tgaggaaatc
      781 agaaagtata acagaatatg ctaaagcctt ttgtaaagct cagctagagg taaagcaacc
      841 actaaaagat aaagacaacc cctttttcaa aagcaaatac gtgcctctag aaaacgtgac
      901 ggaagcgatt acaaaagcct ttgctaataa cgggatatct ttttcgcagg atccaacaac
      961 aaacacagaa aacggttata tcgatgtcgc aacgctagtc atgcacacga gtggcgaatg
     1021 ggtggaatac ggacctttaa gtgttaaacc aacaaaaaat gatgtacaag gagctggttc
     1081 ggctatcact tacgcaaaac gctacgcact atcagcaatt tttgggataa caagcgatca
     1141 agatgatgac ggcaatgaag ctagcaaacc caacaaaaca aatcaatcgc aaaaaccaac
     1201 aaataaaacg tcaaaagggg caagtttcca aaccccgaaa atcagcaata tccaagtaga
     1261 gacttataaa tctgatttaa gcgatattgc aaaagccaca aatcaaaatg tcgaagagct
     1321 aacaaaatgg ctaacagata ccttaaaagt taaatcactg gaagatttac gcacagaaca
     1381 gattgtatcg actgatgatt tgattaataa attaaaaaag agagcagggc aaaaaaatga
     1441 ttaacaacat tgtgctagtt ggtcgcatga ccaaggacgc agagcttcgc tatacagcga
     1501 gtcaagtagc tgtagctacg ttcacacttg cggtaaaccg cagatttaaa gagcaaaacg
     1561 gggagagaga agcagatttc attaactgtg ttatctggcg acagtctgct gaaaatctgg
     1621 caaactgggc taaaaaaggt gccttgatcg gaattacagg tcgtatccag acacgcaact
     1681 acgaaaacca acaaggtcaa cgtgtctatg taacagaagt tgttgcagag agtttccaaa
     1741 tgttggaaag ttgcaatcaa caatctggtc aaggtaactc ttcgcaaaac gataacagtc
     1801 aaccgtttgg caattcaaac ccaatggata tttcagatga tgatctgccg ttttaaatga
     1861 tatggctaac agatatagac aaaggatata tgcggtctac gacggagact cttttgtaga
     1921 tgttggcaca aagcatgagc tagcagaaag acttggtgtt accgctgaca caatagtttt
     1981 tatagcgtcg ccagctcata aaaagaggag accagatggc agacacgcag agtttatagg
     2041 atacgaagac gaattggagg agtagtggtt aagtttataa taccgattga gccaaaaccg
     2101 caaaaacgcc cacgctttag cagatggagt ggagcttacg aggatggaga tatgatggca
     2161 tggcggaagc aggtcacaga ctatgttaaa aacaattacg aagggcctta ttttgacgac
     2221 ggtttaaaag ttgatgttac tttttatcta aaagcaccag aattggtgtc taaaaagccg
     2281 tcagagcgtg ccaaagataa gactaaacaa aagtatcagg attatataaa tgagctctta
     2341 tatgtgccaa agaagcccga tttggacaac cttgaaaaag cagtctatga cagcatatca
     2401 aaatcagagg ttgtgtggac agatgacaac atcattgtcg agcacactac acgtaagctg
     2461 tatagcccaa atcccagaat cgaggtaaaa ataaacgaat tatgacacta gtagatgatt
     2521 tttacaaaca aatggagccg tcaattaaag cgtttttaga cgataacatt accatcgcag
     2581 ataaagaaga agctgacaga gtctatagat ctgtcaaatg ctataaaaaa ctaaacagat
     2641 tgccgccgcc tgatgtattg gagtggttcc aacgaatcta cacgacagag gaaatgataa
     2701 tgttaatcaa gcagtcttac cg
//
LOCUS       DAXMQE010000076         2651 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.076, whole genome shotgun sequence.
ACCESSION   DAXMQE010000076 DAXMQE010000000
VERSION     DAXMQE010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2651)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2651)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2651
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.076"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            complement(<1..770)
                     /locus_tag="ACF4ZO_001885"
     CDS             complement(<1..770)
                     /locus_tag="ACF4ZO_001885"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004134 - 4-alpha-glucanotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HFD5487381.1"
                     /translation="MNKRASGILMHISSLPGKFGIGTFGKSAFEFVDFLAETKQTYWQ
                     ILPLTTTSFGDSPYQSFSAIAGNTHFIDFELLVADGYLQEADLVGVDFGSDPEVVDYA
                     QIFQARRPLLEKAVQAFLATKEGIKELAAFEAEASWLGDFAEFMSLKEHFQNKALQEW
                     DDRAIVKREEAALHHYRELLAKKITYHKVCQYFFYQQWSALKIYANHKGIEIIGDMPI
                     YVSADSVEVWTMPELFKVDSDKKPLFIAGVPADGFSEDG"
     gene            complement(884..1903)
                     /locus_tag="ACF4ZO_001886"
     CDS             complement(884..1903)
                     /locus_tag="ACF4ZO_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFD5487382.1"
                     /translation="MVTIKDVAQKAGVNPSTVSRVLKDNRSISMKTKEKVRKAMADLG
                     YVPNVAAQILASGLTHNIGLVFPPITTSDRLSEPFFMEILSTITNEAKESHFTVSIAT
                     GISLVDLIEQVKLMHLQKRVDGFIILYSDQDDPVKKYLMTNNLPFVIVGAPQGDTNKT
                     TYIDNDNQLMAKTAVEHLYQKGHHNILFITDDLLSEVTSERYLGYLKGCFKRSLKTKP
                     MLLFDRKDPVSVEILMETISSFKATALVVVGDVLAIRMVQLLSFYDIKVPDDMSIITF
                     NNSNYAKLIHPYLTTFDINVENLGKMSFKQLLDIINSNEQNLSQTIFVPFSLKQRESV
                     RDISH"
     gene            2147..>2651
                     /locus_tag="ACF4ZO_001887"
     CDS             2147..>2651
                     /locus_tag="ACF4ZO_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HFD5487383.1"
                     /translation="MKSWQKVIVGGASLTLASTLLMGCGSGSKDKKEAGADSKTIKLW
                     VPTGSKKSYADTIAKFEKDSGYTVKVVESEDPKAQEKIKKDASTAADVFSLPHDQLGQ
                     LVESGTIQEIPEKYNKEIAATSTDQALVGAQYKGKTYAFPFGIESQVLFYNKSKLAAE
                     DVTSYDTI"
BASE COUNT          876 a          510 c          430 g          835 t
ORIGIN      
        1 ccatcttcac taaagccatc tgctggtaca cctgcaataa acaatggctt tttatcacta
       61 tctactttaa atagctcagg catcgtccaa acttctacac tgtccgcaga aacataaata
      121 ggcatatcac caataatttc tatcccttta tggttagcgt aaattttcaa ggctgaccat
      181 tgttggtaaa agaagtattg acagacttta tgataggtaa tcttttttgc aagcaactca
      241 cggtaatgat gcaaggctgc ttcttcgcgt ttcacaattg ctctgtcatc ccattcttgt
      301 agggccttat tttgaaagtg ttctttcaat gacatgaact cggcaaagtc acccaaccaa
      361 ctcgcttctg cttcaaaagc tgccaattct ttgatgcctt ctttagttgc aagaaaggct
      421 tggaccgctt tttctaataa ggggcgtctt gcctgaaaaa tctgagcata gtcaaccacc
      481 tcagggtcag aaccaaaatc aacgccaacg agatcagctt cttgcaagta gccgtctgca
      541 acaagtaatt caaaatcaat gaaatgtgtg ttcccagcaa tagctgaaaa tgactgataa
      601 ggagaatctc caaaactcgt cgttgttaaa ggcagaattt gccaataggt ttgtttcgtc
      661 tctgctagaa aatcaacaaa ttcaaaagct gattttccaa aagtgcctat cccaaatttc
      721 ccaggcaggg aactaatatg cattaagata ccgcttgcac gtttgttcat gatttttctc
      781 cttgtgaaat ctattcatga tgagattata acgcaagcgc ttgcgtaagt caaccagttt
      841 cctaaaaaaa gtaacattcc ttaaaaatgc tacttttttg ttcttaatga ctaatatcac
      901 ggacgctttc tctttgtttt aaactaaaag gaacaaaaat agtctgacta agattctgtt
      961 cattggaatt gataatatca agtaattgct taaaagacat ttttccaaga ttttcaacat
     1021 ttatatcaaa tgtcgttaaa taagggtgaa ttaatttagc gtaattagaa ttattaaaag
     1081 tgataattga catatcatct ggcactttta tatcataaaa agataataac tgtaccatac
     1141 gaatagccag aacatcacca acaacaacca aggcagttgc tttaaaggaa gatatagttt
     1201 ccatcaatat ttctacgcta acaggatcct tacgatcaaa taacagcatt ggcttcgttt
     1261 ttaaagatcg cttaaaacaa cccttcaaat agccaagata acgctcagaa gttacttctg
     1321 atagtaaatc atctgttata aataatatgt tgtgatggcc tttttgataa aggtgttcta
     1381 ctgctgtttt ggccattagc tgattatcat tatcaatata agtggtttta ttagtgtcac
     1441 cttgtggagc acctacaatg acaaatggta agttatttgt catcaaatat tttttgacag
     1501 gatcatcttg atcagaataa agaataataa aaccatcaac tcgtttttga agatgcatca
     1561 gtttcacttg ctctatcaga tcaacaagag atatacctgt agcaatcgac acagtaaaat
     1621 gagattcttt agcttcgtta gtaatagtcg acaaaatttc cataaagaaa ggttcactta
     1681 atctatcgct agttgtaata ggaggaaaaa caagtcctat attgtgtgtc aaaccactcg
     1741 ctagaatctg tgctgcgaca tttggaacat atcccaaatc tgccatcgct tttctaacct
     1801 tctcttttgt tttcatagaa atagatcgat tatcttttaa taccctactc accgtcgaag
     1861 ggttaacacc tgccttttga gcgacatctt ttattgttac catattaacc tcgttactat
     1921 atttaccaaa gataaacctt atcatgggtt tgtcatgtat ttcgtttcca ttatacaatt
     1981 atctttcaaa aaatcaactt caatcaagat tcccttgtca ttttaactca aattctctaa
     2041 actatttttt aaaaaaaacg accttttttt taaaaaaagc ttgacttttt ctgcaagcgg
     2101 ttgcataata ttaagtgtaa gaaatatacc ttaggaggaa atagctatga aatcatggca
     2161 aaaagttatc gtcggcggag caagtttgac acttgcaagt accttgttaa tgggatgtgg
     2221 atcaggttca aaagataaaa aggaagctgg cgctgactca aagactatta aactttgggt
     2281 accgactggc tctaaaaaat catatgcaga taccattgca aaatttgaaa aagattctgg
     2341 ttacaccgtt aaagtggttg aatcagaaga tccaaaagca caagaaaaaa tcaaaaaaga
     2401 tgcctcaact gctgccgatg tcttttcact tcctcatgat caacttggtc aacttgtaga
     2461 atctggtact attcaagaaa ttccagaaaa gtacaataaa gaaattgctg ctacttctac
     2521 tgatcaggcg ctcgtcggtg cacagtacaa agggaaaaca tatgctttcc catttggtat
     2581 tgaatcacaa gttcttttct acaataaatc aaaattagct gctgaagacg ttacttcata
     2641 tgatacaatt a
//
LOCUS       DAXMQE010000077         2486 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.077, whole genome shotgun sequence.
ACCESSION   DAXMQE010000077 DAXMQE010000000
VERSION     DAXMQE010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2486)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2486)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2486
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.077"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            102..1478
                     /gene="mnmE"
                     /locus_tag="ACF4ZO_001888"
     CDS             102..1478
                     /gene="mnmE"
                     /locus_tag="ACF4ZO_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002888396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HFD5487384.1"
                     /translation="MSITKEFDTITAISTPLGEGAIGIVRLSGTDALAIAQSVFKGKN
                     LEQVASHTINYGHIIDPKTGTIIDEVMVSVMLAPKTFTRENVVEINTHGGIAVTNEIL
                     QLLIRQGARMAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMTIAVKQLDGSLS
                     QLINDTRQEILNTLAQVEVNIDYPEYDDVEEMTTALLREKTQEFQSLLENLLRTAKRG
                     KILREGLSTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNIKGVPLKL
                     VDTAGIRETDDLVEQIGVERSKKALQESDLVLLVLNASEKLTDQDRALLNLSQDSNRI
                     ILLNKTDLEQKIELEQLPDDYIPISVLTNQNINLIEDRINQLFFDNAGLVEQDATYLS
                     NARHISLIEKAVQSLEAVNDGLALGMPVDLLQVDLTRTWEILGEITGDAAPDELITQL
                     FSQFCLGK"
     gene            complement(1546..>2486)
                     /locus_tag="ACF4ZO_001889"
     CDS             complement(1546..>2486)
                     /locus_tag="ACF4ZO_001889"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016805 - dipeptidase activity [Evidence
                     IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="Sapep family Mn(2+)-dependent dipeptidase"
                     /protein_id="HFD5487385.1"
                     /translation="GDMDYYFAHNGLKNPDFGFSPDAEFPIINGEKGNITEYLHFAGD
                     NKGAFVLYRFQGGLRENMVPESATAVITAPHDLDMLEAALEQFLSEHGVKGSMKATDG
                     KIEVTIIGKSAHGSTPEAGVNGATLLAKFLNQFTFEGAAKDYLHVAGEVLHEDFAAEK
                     LGLAYTDDRMGALSMNAGVFTFDSQSADNTIALNFRYPKGTDAATLKAGLEKLPGVIK
                     VSLSEHEHTPHYVPMDDELVATLLAVYEKQTGLKGYEQVIGGGTFGRLLERGVAFGAM
                     FPGDENTMHQANEYMPLENIYRSAAIYAEAIYELIK"
BASE COUNT          733 a          541 c          498 g          714 t
ORIGIN      
        1 attttttttt agtattagct aaactcaaaa tggtgctagt cctattttct atacaaaata
       61 ataccttgct ttctattagg acttgattta aaatagaggg catgagtata actaaagaat
      121 ttgatacaat taccgccatt tcaacccctc ttggtgaagg agctattggc attgttcgtc
      181 tatcagggac agatgcgctt gccattgcac aatctgtttt taagggaaag aacttagagc
      241 aagtcgcctc acacactatt aactatggcc atatcattga tcctaagaca ggaactatta
      301 tcgatgaagt tatggtgtca gtcatgctgg ctcccaaaac ctttacccgt gaaaatgtgg
      361 ttgaaataaa tacgcacggt ggtattgctg tgacaaatga aatcttgcaa ctattgattc
      421 gccaaggcgc tagaatggca gagcctggcg aattcaccaa acgtgccttc ttaaatggtc
      481 gtgttgattt gactcaagct gaggctgtca tggacattat tcgtgccaaa acagacaagg
      541 ctatgacgat tgcagtcaag caactggatg gctccctttc ccagcttatc aatgacaccc
      601 gtcaggaaat tctcaacacc ttagctcaag tcgaagtcaa tattgactac cctgaatacg
      661 acgatgtgga agaaatgacc actgctctgc tacgtgagaa aacacaagaa ttccaaagcc
      721 ttttggaaaa tctccttcga acagctaaac gcggtaaaat tctgcgtgag ggcttatcaa
      781 cagctattat tggtcgtcca aacgtcggta agtcaagctt acttaataat ttgttgcggg
      841 aagacaaggc tattgtgact gatattgcag gaaccacccg agatgtcatt gaagaatacg
      901 ttaatatcaa gggagttcct ctaaaacttg tcgatacggc cggtattcgt gagacagatg
      961 atctggtcga acaaatcgga gttgaacggt ctaaaaaagc tcttcaagaa tctgaccttg
     1021 ttcttcttgt gctaaatgct tctgaaaaac tgaccgacca agaccgggct ttgttaaatc
     1081 tcagtcagga cagtaaccgt attatattgt tgaataaaac ggatttggaa caaaagattg
     1141 aattagagca attaccagat gactatattc ccatttccgt tttaaccaac caaaacatta
     1201 atctgatcga agatcgtatc aaccagctct tctttgataa tgctggacta gtagagcaag
     1261 atgccactta cctgtcaaat gcccgccaca tttctttgat tgaaaaggca gtccagagtt
     1321 tagaagctgt caatgacggc ttagcgcttg gcatgccagt tgatttacta caggttgatt
     1381 taaccagaac ttgggaaatt ctcggagaaa tcacagggga tgctgctcct gatgaactca
     1441 ttacccaact ctttagccaa ttttgtcttg gtaaataaga ccattttcta atcatcacaa
     1501 aagagctgga acactgttcc agctcttttt gctgtcataa gcatcttatt taattaattc
     1561 gtagattgct tcagcataaa tagctgctga gcgataaata ttttctaaag gcatatattc
     1621 attagcttgg tgcatagtgt tttcatcacc tgggaacatt gctccaaagg ccacaccacg
     1681 ttctagcaag cgcccaaagg ttcctccgcc gataacttgt tcgtagcctt taagacctgt
     1741 ttgtttttcg taaacagcaa gtaaggtagc tactaattca tcatccattg gcacataatg
     1801 aggtgtatgt tcatgctcag aaaggcttac cttaattact cctggtaatt tttccaagcc
     1861 tgcttttagg gttgccgcat cagttccttt tggatagcgg aaattcaagg cgatggtatt
     1921 gtcagctgat tgactatcaa aggtgaaaac acctgcgttc atgctcaggg ctcccatacg
     1981 gtcatcggta taagcaaggc ctagtttttc tgccgcaaag tcttcatgaa gcacctcacc
     2041 tgccacatgt aaataatcct tagcagcccc ttcaaaggta aattgattca ggaatttagc
     2101 caacaaggtg gcaccattaa cacccgcttc tggagtcgac ccgtgagcag acttaccaat
     2161 aatggtcact tcaattttac catcagtagc cttcatagaa cctttaacac catgttctga
     2221 taaaaattgc tccaaagctg cttctagcat atcaaggtca tgcggtgccg taatgacagc
     2281 tgtggcagat tctggtacca tgttttcacg caacccacct tggaagcgat aaagcacaaa
     2341 agcgcccttg ttgtcaccag cgaaatggag gtattcggtg atatttcctt tctcaccatt
     2401 gataattgga aattcagcat ctggtgagaa accaaagtct ggatttttca aaccgttatg
     2461 ggcaaagtaa taatccatat cacccc
//
LOCUS       DAXMQE010000078         2425 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.078, whole genome shotgun sequence.
ACCESSION   DAXMQE010000078 DAXMQE010000000
VERSION     DAXMQE010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2425)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2425)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2425
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.078"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            103..831
                     /gene="pyrH"
                     /locus_tag="ACF4ZO_001890"
     CDS             103..831
                     /gene="pyrH"
                     /locus_tag="ACF4ZO_001890"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0033862 - UMP kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HFD5487386.1"
                     /translation="MEPKYQRILIKLSGEALAGEKGVGIDIPTVQAIAKEIAEVHVSG
                     VQIALVIGGGNLWRGEPAADAGMDRVQADYTGMLGTVMNALVMADSLQHYGVDTRVQT
                     AIPMQNVAEPYIRGRALRHLEKNRIVVFGAGIGSPYFSTDTTAALRAAEIEADAILMA
                     KNGVDGVYNADPKKDANAVKFDELTHGEVIKRGLKIMDATASTLSMDNDIDLVVFNMN
                     EAGNIQRVVFGEHIGTTVSNKVCD"
     gene            860..1417
                     /gene="frr"
                     /locus_tag="ACF4ZO_001891"
     CDS             860..1417
                     /gene="frr"
                     /locus_tag="ACF4ZO_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008135 - translation factor activity, RNA
                     binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HFD5487387.1"
                     /translation="MANAIIETAKERFAQSHQSLSREYASIRAGRANASLLDRIQVDY
                     YGAPTPLNQLASITVPEARVLLISPFDKSSIKDIERALNASDLGITPANDGSVIRLVI
                     PALTEETRKELAKEVKKVGENAKIAIRNIRRDAMDDAKKQEKAKEITEDELKTLEKDI
                     QKATDDAIKEIDRMTAEKEKELLSV"
     gene            1525..2382
                     /locus_tag="ACF4ZO_001892"
     CDS             1525..2382
                     /locus_tag="ACF4ZO_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HFD5487388.1"
                     /translation="MNDLLATVITGLIKEENANDYFIQKEGFTFTLSKAEGERQIGDM
                     VTGFAYTDIKQKARLTTKEIRSTRTSYGWGEVTEVRRDLGVFVDTGIPNKEIVVSLDM
                     LPEMKELWPKKGDKLYIRLEVDKKDRIWGLPAEPEVFQKMASPAYNNMQNQHWPAIVY
                     RLKLTGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMIVTYLEANGGFMTLNDKSSPEEIKAAFGISKGQFKKALGGLMKAKRIKQ
                     DATGTELIG"
BASE COUNT          786 a          430 c          548 g          661 t
ORIGIN      
        1 gggattttaa ttgacattta ttagcctcta aaatgtcctt tccctattca taattgaggg
       61 tttgtggtaa aatagtaagg acaaactaag gagaacatag tagtggaacc taaatatcaa
      121 cgtatattaa ttaagttatc tggtgaagca ttagcaggtg aaaaaggagt tggcattgac
      181 attccaactg ttcaggctat tgcaaaagaa attgccgaag ttcatgtgtc gggagtacag
      241 atcgctcttg ttattggtgg aggcaatctc tggcgtggag agcctgcagc agacgctgga
      301 atggaccgtg ttcaggctga ttacactggc atgcttggaa cggtgatgaa tgccctagtc
      361 atggctgata gtcttcaaca ttatggtgtt gatacccgtg tgcaaacagc tattcctatg
      421 caaaatgtag cagaacctta tattcgcgga cgtgccttgc gccatctaga aaaaaatcgg
      481 attgttgttt ttggagctgg tattggctcg ccttattttt caacagacac caccgcggca
      541 ctgcgtgctg ctgagattga agcagatgct attttaatgg caaaaaatgg tgtggatggg
      601 gtctataatg ctgatcctaa aaaagatgct aatgcggtta aatttgatga attaacacat
      661 ggtgaagtga tcaaacgtgg tctcaaaatc atggacgcaa cggcatcgac cttatcgatg
      721 gataacgata ttgatttggt ggttttcaat atgaatgaag ctggcaatat tcaacgtgtt
      781 gtctttggag aacatattgg aactactgta tcaaataaag tttgtgacta aaagttagaa
      841 aagaaagaga gtaattatca tggcaaatgc aattattgaa actgcaaaag aacgttttgc
      901 acaatcccat cagtctttat cacgtgaata tgccagcatt cgtgcgggtc gtgccaacgc
      961 tagtctttta gaccgtatcc aagttgatta ttacggggca ccgacgccat taaatcaatt
     1021 ggcttcaatc actgtgccag aagcgcgtgt cttattgatc tcgccttttg ataaatcttc
     1081 tatcaaagat atcgagcgcg ctcttaacgc atcagattta ggcattacac cggctaacga
     1141 tggctctgtc attcgtttgg ttattccagc tttgaccgaa gaaacacgta aagaattagc
     1201 caaagaagtg aaaaaagttg gtgaaaatgc taaaattgca atccgtaata tccgccgcga
     1261 tgctatggat gatgctaaaa agcaagaaaa agcaaaagaa atcactgaag atgagttaaa
     1321 aacacttgag aaagatatcc aaaaagcaac cgatgatgct atcaaagaaa ttgaccgcat
     1381 gacggctgaa aaagaaaaag aattgctctc agtgtaacag gatttctacg aaaaatagac
     1441 gactatagac acaaaaagat aggtgaccat ttcagaagcg tttggttttg atttgtccct
     1501 attttttaaa gaaagaaaaa agatatgaat gatttactag caacagtcat tactgggctt
     1561 attaaagaag aaaacgctaa tgactatttt atccaaaaag aagggtttac ctttaccttg
     1621 tctaaagcag aaggagaacg ccagattggt gatatggtca caggctttgc ctatacagac
     1681 ataaagcaaa aggcacgtct cacaaccaaa gagatccgtt caacacggac aagttatggc
     1741 tggggggaag tgacagaggt tcgtcgtgac ctaggcgttt ttgttgatac aggaattcca
     1801 aataaagaaa ttgtggtttc tttggacatg ttgcctgaga tgaaagaact atggcctaaa
     1861 aaaggggata aactttacat tcgcttagaa gtggataaaa aagaccgtat ttggggactt
     1921 ccagcagagc ctgaggtctt tcaaaagatg gctagccctg catacaataa tatgcaaaat
     1981 caacattggc cagcaattgt ttaccgccta aaactaacag gaacttttgt ttacctgcct
     2041 gaaaacaaca tgttgggctt tattcaccca agtgaacgct acgcagaacc gcgcttaggt
     2101 caggttttag atgcccgtgt gattgggttt agagaggtcg atcgtacctt aaacttgtcg
     2161 ttgaaaccac gttcttttga gatgttggag aatgatgctc agatgattgt cacctatctg
     2221 gaagccaatg gtggtttcat gaccttaaat gacaaatcaa gtccagaaga gattaaagca
     2281 gcctttggta tttcaaaagg ccagtttaaa aaagccttgg gtggattgat gaaagctaaa
     2341 cgtatcaaac aagacgccac aggaactgaa ttaataggat aaaaatgctt tgccactggc
     2401 aaagtttttt gttacaatga agacc
//
LOCUS       DAXMQE010000079         1921 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.079, whole genome shotgun sequence.
ACCESSION   DAXMQE010000079 DAXMQE010000000
VERSION     DAXMQE010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1921)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1921)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1921
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.079"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            <1..1275
                     /locus_tag="ACF4ZO_001893"
     CDS             <1..1275
                     /locus_tag="ACF4ZO_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gp58-like family protein"
                     /protein_id="HFD5487389.1"
                     /translation="SAKITTTSSGTTEAYENKLEGLRAEFTRSNQGMRTELESQISGL
                     RAVQQSTASQISQEIRNREGAVSRVQQNLASYQRRLQSAEGNYNSLRETVAGYERRIS
                     NQDNTISSNFTQLKSLINQSVTLEKIQSLLRLSGDSIMLAIKDKIPQSKMSGSDIISA
                     INLNSYGVTIAGKHIALDGNTTVNGTFTTKIAEAIKIRADQIIAGTIDAAKIRVINLN
                     ASSIVGLDANFIKAKIGYAITDLLEGKVIKARNGAMLIDLNSAKLDFNSNATINFNSR
                     DNALVRKDGTHTAFVHFSNATPKGYTGSALYASIGITSSGDGVNSASSGRFAGMRCFR
                     HATGYNHTAAVDQTEIYGDSVLIADDFNINRGFKFRPDKTKKILDMNNLYDAVVALGR
                     CWGHLRNAGWDTARSNFITAVTRELSNYIDII"
     gene            1287..1715
                     /locus_tag="ACF4ZO_001894"
     CDS             1287..1715
                     /locus_tag="ACF4ZO_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1617 family protein"
                     /protein_id="HFD5487390.1"
                     /translation="MDLTLKNKDLNTFYSVLGKIKITNMRANRGRAKLLAKVVDKINE
                     YAKDEADIIDLYALKNKDGKFVIDEHKNIKIEDPKKIDELNDLLTELGNEDITIKGHE
                     YSKRFIDFLEYLAESEDEFTSEEIVLIDNILEQFEESKGE"
     gene            1718..>1921
                     /locus_tag="ACF4ZO_001895"
     CDS             1718..>1921
                     /locus_tag="ACF4ZO_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1366 domain-containing protein"
                     /protein_id="HFD5487391.1"
                     /translation="MRNWKVTGKYPQYDSTGAVASTHIIITAEDGAVIPQLIKQDLTS
                     TNDTEIIKAALEEFKKSEYVEIAM"
BASE COUNT          643 a          398 c          413 g          467 t
ORIGIN      
        1 tctgctaaga tcacaacaac ctcaagcggc acgaccgaag cctacgaaaa caagctcgag
       61 ggtttacgtg ctgagtttac tcgtagtaat caaggcatga ggacggagct cgagtctcaa
      121 atcagcggac taagagctgt acagcagtca acagctagcc aaatctcaca agagatacgt
      181 aaccgcgaag gagctgtcag tcgtgtgcag cagaacttag ctagctatca gcggcgatta
      241 caatccgcag agggcaatta caacagtttg agagagactg tagcgggtta tgagcgcagg
      301 atatccaatc aggataacac tatctcctct aactttacac agctaaaaag cttgataaat
      361 cagtctgtga ccttagaaaa aattcagtcc ctcttgaggc tatctggtga cagtatcatg
      421 cttgcgatta aagacaaaat cccgcaaagt aaaatgtctg gcagcgatat tatctcagcg
      481 attaacttaa actcctacgg agtaacaatc gcaggtaaac acatcgctct cgatggcaat
      541 acgactgtca acggcacctt taccacaaag atagcagagg ctatcaaaat cagagctgat
      601 cagattattg caggcacgat tgacgctgct aagattagag tgattaacct taacgcaagt
      661 agtatcgttg gtttagacgc taactttatc aaagctaaaa ttggctatgc tatcactgat
      721 ttgctcgagg gcaaagtcat caaagctcgt aatggcgcta tgcttatcga ccttaacagc
      781 gctaagcttg attttaacag taacgcgacc atcaacttta acagccgaga taacgctcta
      841 gtgcgtaaag acggtacaca cactgccttt gtacacttta gtaatgccac accaaaaggt
      901 tatacaggtt cggcactata tgcctctatt ggtatcacct catctggtga tggggtcaac
      961 agtgcgtcat ctggacgttt tgcgggtatg cgttgcttta ggcacgctac aggctacaac
     1021 cacactgcgg cagtcgacca gacagaaatt tatggtgata gtgtacttat tgcagatgac
     1081 tttaacatca atagaggctt taagtttaga ccagacaaga cgaaaaaaat ccttgatatg
     1141 aacaacttgt atgatgctgt tgttgcactc ggacgttgct ggggacatct gaggaatgcc
     1201 gggtgggata ccgctcgcag caattttata actgctgtca ctagagagtt gagtaattac
     1261 attgatatta tttaaaagga gacaacatgg atttaacact aaaaaataaa gacttaaaca
     1321 cgttttatag cgtacttggc aaaatcaaaa tcactaatat gcgtgccaac cgtggacgtg
     1381 ccaagctact ggcaaaagtg gtcgataaaa tcaacgagta cgccaaggat gaggctgaca
     1441 ttattgactt gtacgctcta aaaaataaag acggcaagtt tgtcatcgac gagcataaaa
     1501 atatcaagat tgaggaccca aaaaaaatcg acgagctcaa cgacttactg acagagcttg
     1561 gtaatgagga catcactatc aaaggccatg agtattcaaa acgctttatc gatttcttgg
     1621 aatatctagc cgaatcagaa gatgaattta catcagagga aatcgtctta attgataata
     1681 ttttggaaca atttgaagaa agtaaaggag aataattatg cgcaattgga aagtaacagg
     1741 gaaatatcca caatatgaca gcacaggagc agtcgcaagc acacacatca ttatcacagc
     1801 agaagatggc gctgttatcc cacaactgat caagcaagac ttaacctcaa ctaatgacac
     1861 agagattatc aaagccgctt tggaagaatt taaaaaatcc gaatatgtcg aaatcgctat
     1921 g
//
LOCUS       DAXMQE010000080         1846 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.080, whole genome shotgun sequence.
ACCESSION   DAXMQE010000080 DAXMQE010000000
VERSION     DAXMQE010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1846)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1846)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1846
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.080"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            116..415
                     /locus_tag="ACF4ZO_001896"
     CDS             116..415
                     /locus_tag="ACF4ZO_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5487392.1"
                     /translation="MHFDLLQIGAACTTLLSILGVWGFIVNPFKKAMEANEFAMAQLK
                     DSIKELAYELKNLDRDREITKKIIDRHEERLGRVEDEVIINKERIITLFKKGEEK"
     gene            412..597
                     /locus_tag="ACF4ZO_001897"
     CDS             412..597
                     /locus_tag="ACF4ZO_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holin"
                     /protein_id="HFD5487393.1"
                     /translation="MNKWFKKVAIKTIKTMAQTAVGLIGSSVLITDINWPTMLSAVLL
                     SGLTCVLMNVSQIKEEE"
     gene            710..>1846
                     /locus_tag="ACF4ZO_001898"
     CDS             710..>1846
                     /locus_tag="ACF4ZO_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HFD5487394.1"
                     /translation="MAFLDKIKSAVIAEWHTHKILPSLTAAQAILESGWGKYAPHNAL
                     FGIKADSSWTGKSFNTKTQEEYQPGIVTDIVDRFRAYDSWEDSIADHGQFLADNPRYK
                     AVIGEADYKKACHAIKDAGYATASGYADLLIQLIEENNLQEWDAEAIKNKEEQMISSQ
                     CREVIEFFINLANAGVGVDKDSFAGWQCADVPCYAAKHWFGVDLWGNAIDLLDSAAAV
                     GWEVHRMPTDANPRTGAFFVQSVPCHQFGHTGIVIEDSDGYTMRTVEQNIDGNPDALY
                     VGAPARFNTRDFTGVLGWFYPPYQGDIVTQPVSTEPQNSDTIVETPKTGTFTLDVAEI
                     NIRRWPSLASEVVGSYKQGDTVSFDSEGYANGYYWISYVGGLGMR"
BASE COUNT          552 a          344 c          456 g          494 t
ORIGIN      
        1 catgttaacg agccatttac ttatgaggca cagaccttag aggagcttga gtcagaggac
       61 aaagtaacag tcatcaaata tgcggaatta gttaaacaag attaggggtg gttagatgca
      121 ctttgattta ttgcagatag gagctgcgtg taccactctc ttgtctatct tgggtgtttg
      181 gggatttatc gtcaacccct ttaaaaaagc catggaagct aatgagtttg ccatggctca
      241 gctcaaggac tcaattaagg agttagctta tgagcttaaa aaccttgatc gtgaccgtga
      301 gattaccaaa aaaattatcg atcgccacga agagcgttta gggcgtgtcg aagacgaagt
      361 tattatcaac aaagaacgta ttattacgct atttaaaaaa ggagaagaaa aatgaataaa
      421 tggtttaaaa aagtagcaat caaaacaatc aaaacaatgg cacaaacagc tgttggtctt
      481 atcgggtcaa gcgtgttgat tacggatatt aactggccaa cgatgttgtc agcggtatta
      541 ctatcaggac taacttgtgt cctgatgaat gtgtcacaaa ttaaagaaga ggagtaacca
      601 tgagaaaagc aatcacacaa ctagccgtca tcatagctat catagtgcta tattttccac
      661 tggccgtgat tgctttgatt ttggctccat ttataggaga ggatgataga tggcattttt
      721 agacaaaata aaaagcgcag ttatcgcaga gtggcacact cataagattt tgccatctct
      781 gacagctgct caagccattt tagagagcgg gtggggcaag tatgctccac ataatgcttt
      841 gtttggtatc aaggcagata gctcttggac tggtaagtca tttaatacaa aaacacagga
      901 agagtatcaa ccggggattg ttacggatat tgtagaccgt tttagggcct acgacagttg
      961 ggaggactct atcgctgatc atggccagtt tttagccgat aatccacgct ataaggcagt
     1021 tattggagag gctgactaca aaaaagcttg tcatgctata aaagatgcag gttatgcgac
     1081 tgcgagtggc tatgcggatc tgttgatcca actgatcgag gagaataact tgcaggaatg
     1141 ggatgccgaa gctataaaaa ataaggagga gcagatgatt agttctcagt gtcgggaagt
     1201 cattgaattt tttattaact tagcaaacgc cggagttggc gtggataaag atagttttgc
     1261 aggctggcaa tgcgcagatg tgccttgtta tgcagcaaag cactggtttg gtgttgacct
     1321 ctggggaaat gccatagact tactagatag cgctgctgcc gtaggctggg aagtccaccg
     1381 catgccgaca gatgcaaatc cacggactgg agcatttttt gtccaatcag tgccatgcca
     1441 tcagtttgga catacgggaa ttgtcattga ggatagcgac ggttatacca tgcgtaccgt
     1501 tgagcaaaac attgatggca atcctgatgc tttgtatgtc ggtgcaccag ctcgttttaa
     1561 cactcgtgat tttactggcg tgttgggatg gttttaccct ccttaccaag gagatattgt
     1621 cacgcaacca gtcagcaccg agccacaaaa ctctgacaca atcgtagaga caccaaaaac
     1681 aggtactttt accctagatg tcgcagagat taatatcaga cgttggccaa gtctcgccag
     1741 cgaagtagta ggtagctaca aacaaggtga taccgttagc tttgacagtg agggttacgc
     1801 caatggttac tactggatta gctatgttgg aggcttaggt atgcgt
//
LOCUS       DAXMQE010000081         1789 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.081, whole genome shotgun sequence.
ACCESSION   DAXMQE010000081 DAXMQE010000000
VERSION     DAXMQE010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1789)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1789)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1789
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.081"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            108..1499
                     /locus_tag="ACF4ZO_001899"
     CDS             108..1499
                     /locus_tag="ACF4ZO_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HFD5487395.1"
                     /translation="MTIFRKKKKYSNKTEMQRHFKVIDLVFLGLGSMVGTGIFTVTGI
                     GAAKYAGPALTISIIISAIAIGILALFYAEFASRMPSNGGAYSYVYATLGEFPAWLVG
                     WYIIMEFLTAISSVAVGWGSYLKGLLANYNIVLPNALNGTFNLKNGTYIDILPVLVMF
                     FVTGIVLMNSKLALRFNSFLVILKFSALALFIFVGIFFIDHNNWSHFAPYGVGQITGG
                     KTGIFAGASVMFFAFLGFESISMAVDEVKEPQKTIPKGIILSLIIVTALYIVVTTILT
                     GIVHYTKLNVPDAVAFALRNIRLYWAADYVSIVAILTLITVCISMTYALARTIYSISR
                     DGLLPKSLYTLTKKNKVPQNATLVTGLLAMICAGIFPLSSLAEFVNICTLAYLIILSG
                     AIIKLRRIEGEPKANEFKTPLVPFLPMLAIIICLSFMSQYKAFTWIAFAIATIIGTLI
                     YLAYGYTHSIENK"
BASE COUNT          579 a          261 c          298 g          651 t
ORIGIN      
        1 agaacagaag atagcaaaag tttcagtcaa ccaataagat gaaatttaca atcattacta
       61 actatgatac acttagtaga aaatcattta ctatagaagg tgataacatg actatttttc
      121 gtaaaaaaaa gaaatattcc aataaaacag aaatgcaaag gcacttcaaa gttattgatt
      181 tagttttttt aggcctaggt tcaatggttg gaacaggtat ctttacagtt actggcatag
      241 gcgctgctaa gtatgcaggt cctgctttaa caatatcgat tatcatttcc gcgattgcta
      301 ttggaatttt agccttattt tatgcagaat ttgcgtctcg tatgccttct aacggtggtg
      361 cttatagtta tgtttatgca accttgggag agtttccagc atggcttgtt ggctggtata
      421 ttattatgga atttttaaca gctatatcta gtgttgctgt tggctgggga agttatttaa
      481 aaggattact tgccaattat aatatagtat taccaaacgc tttaaatggc acgttcaatc
      541 ttaagaatgg aacttacata gatattcttc ctgttttagt gatgtttttc gtgacaggga
      601 ttgtcctaat gaattcgaaa ttagccctga gattcaatag ttttttagtt attttaaaat
      661 tttcagcact ggctttattt atctttgtag gcattttttt tattgatcac aataattggt
      721 ctcattttgc tccatatggt gtaggacaaa ttactggagg taaaacaggt atctttgctg
      781 gtgcttctgt tatgttcttt gcatttttag gatttgaatc tatttcaatg gcagttgatg
      841 aagtgaaaga accacaaaaa acaattccta aaggtatcat tttatctttg attattgtaa
      901 cagcactcta tatagttgtc accactattt taacgggaat tgtacactac actaaattaa
      961 atgttccaga cgcggtggct tttgctttaa gaaatattag actttattgg gcagctgact
     1021 atgtgtcgat agttgctatt ttgactctta ttacggtatg tatttctatg acctatgcat
     1081 tagctagaac aatttacagt attagtagag atggtttatt acctaaatca ctttatactc
     1141 tcactaaaaa aaataaagtg cctcaaaatg ctactcttgt cactggacta cttgctatga
     1201 tttgtgcggg aatatttcct ttatcgagtc tagcagagtt tgttaatatt tgtactttag
     1261 catatttaat tattctgtcg ggtgcaatta ttaaactcag aagaatagaa ggagaaccaa
     1321 aagcaaatga atttaaaact cctctagtac cattcctacc aatgttggca attatcattt
     1381 gtctatcatt tatgagccaa tataaagctt ttacttggat tgcttttgct attgccacaa
     1441 ttattggaac attaatctac ttagcttatg gttatactca ttcaatagaa aataaataat
     1501 gttttgataa taagatttga cattacatta tagactataa tgtttagaag taaatgagta
     1561 gtaaaatcaa tacctactta cttatcaaag ttgtaatatt taaaattacc caacccctag
     1621 agaattgatt agtctctagg ggttgattgg cacaatgaca tagactctaa aacgatttta
     1681 atactaaata tatagatata aatttcaaaa aagaaaatta gttcattttt gttacacaat
     1741 aaaatttgtt atttagcagt aatataattg aaaaacagca acattttgt
//
LOCUS       DAXMQE010000082         1763 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.082, whole genome shotgun sequence.
ACCESSION   DAXMQE010000082 DAXMQE010000000
VERSION     DAXMQE010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1763)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1763)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1763
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.082"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            complement(30..872)
                     /gene="licT"
                     /locus_tag="ACF4ZO_001900"
     CDS             complement(30..872)
                     /gene="licT"
                     /locus_tag="ACF4ZO_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator LicT"
                     /protein_id="HFD5487396.1"
                     /translation="MLIKRVLNHNSAISTNHQGLDILLMGKGIAFGKKVGDSIELNAI
                     ETSFVLKNSDNMNRFTELFITVPQEVVACSERIINLGKIKLGKTLDEILYINLTDHIH
                     SAIERHEQGMLIHNPLRWEIQRYYPDEYSLGVKALELIERNLGVTLAIDEAAFIAMHF
                     VNASLDTPFKEPHRLTEIVSYIEQKIKTDFKTELDDTSIDYYRFMTHIKLFAQRVLSE
                     MSYDDDDAELLLVVKTKYPKEYRCVLDISEEIKKRYNYHLNSSELLYLTVHVKRLVKH
                     LKET"
     gene            1200..>1763
                     /locus_tag="ACF4ZO_001901"
     CDS             1200..>1763
                     /locus_tag="ACF4ZO_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFD5487397.1"
                     /translation="MSHHQQTVSKQTIMAIIAIALIGFSGILSETSMNVTFPTLMSVY
                     QLPLNSLQWMTTIYLLAVAIMMTTSATLKKNVRERPLFFMATGLFTFGTILAVLTQSF
                     AIMLLARIFQGIGTGLVMPQMFNIILERVPMHKVGLFMGFAGLIISLAPAFGPTYGGF
                     MISHFSWQWIFICILPVPLIAGILAYYY"
BASE COUNT          518 a          349 c          298 g          598 t
ORIGIN      
        1 tagccttggc agtttcttga tacgtcatat taagtctcct ttaaatgttt cactaaacgt
       61 ttaacatgaa ccgtcaaata caaaagttcg cttgaattaa ggtggtagtt gtaccgcttt
      121 tttatctcct cactaatatc taagacgcac cgatattctt tagggtattt cgttttcacc
      181 actaaaagca gttccgcatc atcatcatcg taagacatct ctgataacac gcgttgagca
      241 aataatttaa tatgggtcat aaagcggtaa taatcgatgg atgtgtcatc caattctgtt
      301 ttgaagtctg ttttgatttt ttgctcaata taagaaacaa tctccgtcag gcgatgtggc
      361 tccttaaaag gagtgtccaa actagcattg acaaaatgca tggcaataaa agctgcttca
      421 tcaatagcta gagtgactcc tagattacgc tcaattagct ctaaggcttt tacccctaga
      481 ctatattcat caggataata gcgttgaatt tcccaccgta gtgggttatg aatcaacatt
      541 ccttgctcat gcctttcaat agcagagtga atatgatccg ttaaattaat atagagaatt
      601 tcatctaagg ttttgcctaa tttaatttta cctagattga taattctctc tgagcaagca
      661 acaacttctt gtggcaccgt aataaataac tctgtgaagc gattcatatt gtcactattt
      721 tttaaaacaa atgatgtttc gatagcatta agctcaatac tatctccaac tttttttcca
      781 aaggcaatcc cttttcccat caataaaata tctaatcctt gatggttggt cgaaatcgcc
      841 gaattatggt ttaaaacgcg tttaatcaac ataaaagtcc tagtccttta gtatcacaat
      901 aaaaaatgac ctatccaaaa gctcgctaaa aagcactttt cgaataggtc cctgctcaca
      961 aaactgtgat aacatccttt aatattctga ttgttatgtc tctagcctgc ttacttgaag
     1021 taatcacatc tgagaacgct ttaatgttat catctcttta agattctgtc aagcgttttc
     1081 aaaaaattct ctgaaagagc aactattgtt attcgtatct attgatttag caaaaaagag
     1141 tttctgacaa ttttaagatt atatgataca ataacaatcg attagataaa ggagttatca
     1201 tgtcacatca tcaacaaacc gtttcaaaac aaacaattat ggcgattatc gccatagcac
     1261 tcattggttt ttcaggaatt ttgtctgaaa ccagtatgaa tgtcaccttc ccgacactga
     1321 tgtcagtcta tcagttgccc ttaaatagct tgcaatggat gacgaccatt tatttactag
     1381 cagtggcgat tatgatgacc acttcggcta cactgaaaaa aaatgtgcgg gaaagacccc
     1441 tcttttttat ggccacaggt ctttttacat ttggcaccat cttggccgtt ctgacccagt
     1501 cctttgcgat catgttgcta gcccgcattt ttcaaggcat tggtactggt ctggtaatgc
     1561 ctcagatgtt taatattatt ttagagcgtg tcccaatgca taaggtaggt ctatttatgg
     1621 gatttgctgg tcttattatt agcttagcac ctgcttttgg gcctacttat gggggcttta
     1681 tgattagcca ttttagttgg caatggattt ttatctgtat actccctgta ccactgattg
     1741 caggtattct agcttattat tac
//
LOCUS       DAXMQE010000083         1688 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.083, whole genome shotgun sequence.
ACCESSION   DAXMQE010000083 DAXMQE010000000
VERSION     DAXMQE010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1688)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1688)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1688
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.083"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            <1..815
                     /locus_tag="ACF4ZO_001902"
     CDS             <1..815
                     /locus_tag="ACF4ZO_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HFD5487398.1"
                     /translation="EISGNLWDAQPYNVEEFTAGKVVSMKGRREVYNGTPQVNQITLR
                     NVRPGEPNDPKDFKEKAPVSVTEVRDYLEQMLFKIENATWQRIVRALYRKYDKEFYTY
                     PAAKTNHHAFESGLAYHTATMVRLADSIGDIYPDLNKSLLFAGIMLHDLAKVIELTGP
                     DNTEYTVRGNLIGHISLINEEITKVISELQIDDTKEEVIVLRHVILSHHGQLEYGSPV
                     RPRIMEAEIIHMIDNIDANMMMMTTALSRVSEGEMTNRIFAMDNRSFYKPNY"
     gene            1082..>1688
                     /gene="purR"
                     /locus_tag="ACF4ZO_001903"
     CDS             1082..>1688
                     /gene="purR"
                     /locus_tag="ACF4ZO_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0045982 - negative regulation of purine
                     nucleobase metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HFD5487399.1"
                     /translation="MKLRRSERMVVISNYLINNPYKLTSLNTFATKYEAAKSSISEDI
                     AIIKKAFEEANIGDIDTLTGASGGVIFTPSISETEARTIVEDLCQRLSESDRILPGGY
                     IYLSDLLSTPKILQNIGRIIANAFKGEKIDAVMTVATKGVPLANAVANILSVPFVIVR
                     RDLKITEGSTVSVNYASASSDRIEKMFLSKRSLKPNSRVLIV"
BASE COUNT          542 a          285 c          343 g          518 t
ORIGIN      
        1 gcgagatttc aggaaatctg tgggatgccc aaccttataa cgttgaagaa tttaccgctg
       61 gtaaagtcgt gtctatgaaa gggcgacgcg aggtctataa tggtacccct caggttaatc
      121 aaatcacctt acgaaatgtt cgcccagggg agcccaatga tccaaaagac ttcaaagaaa
      181 aggcacctgt cagtgtgaca gaagtacgtg actatttgga acagatgctc tttaaaattg
      241 aaaatgcaac gtggcaacga attgtaaggg ctctttatcg taagtatgat aaagaatttt
      301 atacttatcc tgcagctaaa acaaaccacc atgcttttga gtcaggcctc gcctaccata
      361 ctgctacgat ggtcagacta gcagatagca ttggagatat ctaccctgac ttaaataaga
      421 gtctactgtt tgcaggtatt atgttacatg acttagctaa agtcatagaa ttaacaggac
      481 cagataatac agaatacacc gttcgtggta acttgattgg gcatatttct ctcattaacg
      541 aagaaatcac aaaagtaatt tcagaactac aaatcgatga taccaaagaa gaagtcattg
      601 tccttaggca cgtgatttta agccatcacg ggcaattaga atacggtagt ccggtacgtc
      661 cacgcatcat ggaagctgaa attattcata tgattgacaa tattgatgct aatatgatga
      721 tgatgacaac agctcttagc cgtgttagcg agggcgagat gaccaatcgg atttttgcca
      781 tggataatcg gtctttttac aagccaaact attgatcagt gtttctcaag taatagttcc
      841 tttgcttttg tgatgatttt tgatgtgctt aacacttatg atggtttcat aagtgttttt
      901 ggctcttgtt atggttatta agtagaatgt cctttcagta ggaatgttga ttagtttatc
      961 ttagattgaa ttcttgcatg atattaataa gaacaaaaaa accaatattt tcctaatcga
     1021 atgttcgttt tttattaact ttatggtata atagcaaaaa gtacataaaa atggggaaac
     1081 tatgaaatta agacgaagtg aacgtatggt tgtcatttca aattatttga ttaacaatcc
     1141 gtataaatta actagtttaa acacctttgc aactaaatat gaggccgcaa aatcttctat
     1201 ctcagaagat atcgctatta tcaagaaagc ttttgaagaa gctaacattg gtgatatcga
     1261 tacacttaca ggagcaagtg gaggcgtaat ttttaccccc agtatttcag aaacagaagc
     1321 gcgtaccatc gttgaagacc tgtgtcaaag gttatcagag agtgatcgca tcttacctgg
     1381 aggctatatc tatttgtcag acttgctgag tacacctaaa attttacaaa atattggtcg
     1441 tattattgcc aatgccttta aaggagaaaa gattgacgct gtgatgacag ttgcaaccaa
     1501 aggagttcct ttagcaaatg cagtggctaa tattttaagt gttccttttg tcattgttag
     1561 acgtgattta aaaataacag aaggatcgac agtgtctgtc aattatgcga gtgcttctag
     1621 tgatcgtatt gaaaagatgt ttctgtcaaa gcgtagtttg aaacccaata gtcgtgtatt
     1681 gattgtag
//
LOCUS       DAXMQE010000084         1619 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.084, whole genome shotgun sequence.
ACCESSION   DAXMQE010000084 DAXMQE010000000
VERSION     DAXMQE010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1619)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1619)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1619
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.084"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            complement(73..339)
                     /locus_tag="ACF4ZO_001904"
     CDS             complement(73..339)
                     /locus_tag="ACF4ZO_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5487400.1"
                     /translation="MKEKTIFISKKYANDFNNDKYNLSSGYYFKNGEQHDIAIVKYGE
                     QDYLKNTDLAYVVCDKIVDGESIGFVYHGEYETWRFKLLNTEAN"
     gene            complement(336..707)
                     /locus_tag="ACF4ZO_001905"
     CDS             complement(336..707)
                     /locus_tag="ACF4ZO_001905"
                     /inference="COORDINATES: protein motif:HMM:NF019467.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HFD5487401.1"
                     /translation="MIKFRKEHDQDLTTTFVNIHAYPDNVFHWVANNGDLFAQAWLAY
                     PNITIEKEKLYTVEIPNPNREGRGHAKFVLERQGNKVFLVKRKSKDCYYNKNSNHLTE
                     SEIRKDFDWAWREGFAEEVTE"
     gene            complement(828..1460)
                     /locus_tag="ACF4ZO_001906"
     CDS             complement(828..1460)
                     /locus_tag="ACF4ZO_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
                     /protein_id="HFD5487402.1"
                     /translation="MIKIDEIHRILGIDEVYKAPKRLTDILFDKDSREDIFRQFLKYE
                     TDVSYDWFMQYFEEEQADRKNKKQDFTPKSVSTLLSKIISGNQYYEVAVGTGGILIQA
                     WQEQRLNDSPFTYRPSKYWYHVEELSDKAVPFLLFNMSIRGINGVVVHGDSLTRQVKN
                     IYFLQNTKDDMLSFSDINVMPRTQDIEREFNVKEWIGDAIVHVESKLNAR"
BASE COUNT          436 a          338 c          262 g          583 t
ORIGIN      
        1 ctcgtttcta ttttttaatt tcggtccacc cccacagagc catcgcaggc tcttgagcgc
       61 ttgcgtggga atttaatttg cttccgtgtt taatagttta aaacgccaag tttcatattc
      121 gccgtgataa acgaagccta tagattctcc atcaacgatt ttatcgcata caacatatgc
      181 taaatcagta ttttttaaat aatcttgttc gccatattta acaatagcaa tatcatgttg
      241 ttcaccattt ttaaaataat agccagagga caaattatat ttgtcattgt taaagtcatt
      301 tgcatatttt tttgatataa aaattgtttt ttctttcatt ccgtcacctc ctccgcaaat
      361 ccttctcgcc atgcccagtc gaaatcttta cgaatttcgg attcagtgag gtgattgctg
      421 tttttattgt agtagcaatc ctttgatttt cgttttacca aaaaaacttt attaccttgt
      481 ctttcaagca caaacttggc atgacctctg ccttccctgt tcggatttgg tatctccact
      541 gtatacagct tctctttttc gatggtgata tttggataag ctagccatgc ttgggcaaat
      601 aaatcaccgt tatttgccac ccaatggaaa acattgtctg gataagcatg tatattaaca
      661 aaagttgttg ttaaatcctg gtcgtgttct tttctaaact taatcatttc agcgaaaaga
      721 gcgataagag aactagaggc gtttaattat ttcgatttta aaggtaattt aattaaacga
      781 attgatgtat taggtatcat cgaccaactc ggccaaccaa aagtggttta cctcgcattt
      841 aacttactct ctacatgcac tatcgcatca ccaatccact ctttgacatt aaattctcgc
      901 tcaatatctt gagttcttgg cataacgtta atatcactaa aactcaacat gtcgtctttt
      961 gtattttgca aaaaataaat gtttttaact tgtcttgtta aagagtcacc atgcaccacc
     1021 acaccattta tccctcttat agacatatta aagagtagaa acggtactgc tttgtccgat
     1081 aactcttcta cgtgatacca gtatttactc ggacgataag taaatggact gtcatttaat
     1141 cgttgttctt gccatgcttg gataagtatc ccacccgtcc cgactgctac ctcgtagtat
     1201 tgattaccac ttattatttt agataatagt gtactaaccg atttaggcgt aaagtcttgc
     1261 tttttatttt tgcggtcagc ttgttcttcc tcaaaatatt gcataaacca gtcgtaagat
     1321 acatctgttt catatttcaa aaactgtcta aatatatcct cacgactatc tttatcaaag
     1381 agtatgtccg taagtcgttt gggtgcttta taaacttcgt cgatgcctag tatgcgatgt
     1441 atctcatcga tcttaatcat gttaccctcc gttgtgcgta agttccgcaa ttcgctttgt
     1501 ctgtctagct ctatcttcgc tagcacgttt aagctgcttt tgtgtcctgc ttagctgtgt
     1561 acgtagtcct gtgatttgcg actcgtaata ttgtcgtgcg tcgcgatagc taaaatacg
//
LOCUS       DAXMQE010000085         1499 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.085, whole genome shotgun sequence.
ACCESSION   DAXMQE010000085 DAXMQE010000000
VERSION     DAXMQE010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1499)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1499)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1499
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.085"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            76..>1499
                     /locus_tag="ACF4ZO_001907"
     CDS             76..>1499
                     /locus_tag="ACF4ZO_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182 family transposase"
                     /protein_id="HFD5487403.1"
                     /translation="MLHKEKPDYNRNQYGFYTLDQIVPDEHFLRQVEAVIDFDFIYDL
                     VEDTYSSDNGRPSLDPVMLVKIPLIQCFYGIRSMRQTIKDIEVNTAYRWFLGLTLDDK
                     VPHFTTYGKNYSRRFQEKGLIESIFTHILGLCINTGLIDPTEIFIDGTHIKAAANTRK
                     FINREVEKQAKFMSEQLEIEINRDREKHGKKPLGPAKELEPVAKKISTTDPESGWFHK
                     GDHKEVFAYSAQVACDKYGWALAYSVEAGNIHDSQAFPALFAKLEPLKPQFIIADSGY
                     KIPSIAKFLIDKEITPVLPYTRPRGKKDLLRPKELIYDEHFDCVICPEHQALTYRTTT
                     REGYREYKSDPAICANCSLLSVCTTSKNRQKVVTRHIWKDYLEQCEDIRHQRGMKELY
                     QHRKETIERLFGTAKEYHNLRYTREKGKSKMEDKVGLTLACLNLKKLVKRMAGEPFYF
                     VQMRWFKHGNSHFYLKTLKKTNTKS"
BASE COUNT          452 a          316 c          335 g          396 t
ORIGIN      
        1 tagaatcgct tttctagggg cttttcatga tatttaggag tataatataa gaaaaaggac
       61 ttgtgaggtt ctcctatgtt acacaaagaa aaacctgact ataaccgcaa tcagtacggt
      121 ttctataccc ttgaccagat agtgcctgat gaacatttcc tgcgccaagt ggaagctgtg
      181 attgacttcg acttcatcta tgacctagta gaagacacct attcgtctga taatggtcgc
      241 cctagccttg atcctgtcat gttggttaaa atccctctga ttcagtgctt ttatggcatt
      301 cgttccatgc gtcagaccat caaggatatt gaagtgaata ctgcctatcg ctggttttta
      361 ggtttgactt tggatgacaa ggtgccacat ttcacaacct atggcaaaaa ttattcccgt
      421 cgctttcaag aaaaaggctt gattgagtcc atttttacgc atattcttgg gctatgtatc
      481 aatacaggcc tgattgaccc gacggagatt ttcatagatg ggactcatat taaggctgcg
      541 gctaatactc gcaagttcat caaccgagag gtggaaaaac aagccaagtt catgagtgaa
      601 cagctagaaa tcgaaatcaa tcgagatagg gagaagcatg gaaaaaagcc gctagggccc
      661 gccaaagagc tagagcccgt cgctaagaaa atctccacaa ccgatccaga aagtggctgg
      721 tttcacaaag gtgatcataa ggaagtcttc gcttattctg ctcaggtggc ttgtgacaag
      781 tatggatggg cgcttgctta tagtgttgag gctggcaata tccatgatag tcaggctttt
      841 cctgcacttt ttgccaagct tgaacccttg aaaccgcagt ttattattgc ggattccggc
      901 tataaaattc ccagcattgc caagtttctg attgataagg agatcactcc tgtccttcct
      961 tacacacggc caagaggaaa gaaagacctt ctacgtccga aagaattgat ttatgatgag
     1021 cactttgatt gtgtcatctg ccctgaacat caagccttga cctaccgcac tacgaccaga
     1081 gaaggctacc gagaatacaa aagtgaccct gcaatttgtg ccaattgttc cctgttatct
     1141 gtatgtacga ccagtaagaa ccgccaaaaa gttgtcacac ggcatatttg gaaagactat
     1201 ttggaacagt gcgaggacat tcgtcatcaa agggggatga aggagctcta ccagcatcgg
     1261 aaagagacga ttgaacgact gtttggcaca gccaaggaat accacaatct ccgctatacg
     1321 agagagaaag gcaagtccaa aatggaagat aaggttggac tgactttggc atgcttaaat
     1381 ctcaaaaaac tggtcaaaag gatggcggga gagccttttt attttgttca gatgaggtgg
     1441 tttaagcacg gaaacagcca tttttatcta aaaacactaa aaaagacaaa caccaaatc
//
LOCUS       DAXMQE010000086         1398 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.086, whole genome shotgun sequence.
ACCESSION   DAXMQE010000086 DAXMQE010000000
VERSION     DAXMQE010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1398)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1398)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1398
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.086"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            complement(<1..207)
                     /locus_tag="ACF4ZO_001908"
     CDS             complement(<1..207)
                     /locus_tag="ACF4ZO_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HFD5487404.1"
                     /translation="MKQSKLLIPTLREMPSDAQVISHALMVRAGYVRQVSAGIYAYLP
                     LANRTIEKFKTIMREEFEKIGAVEM"
     gene            complement(405..>1398)
                     /gene="rseP"
                     /locus_tag="ACF4ZO_001909"
     CDS             complement(405..>1398)
                     /gene="rseP"
                     /locus_tag="ACF4ZO_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HFD5487405.1"
                     /translation="EQGFVKRINLSQSKLDPTSLPMHVTGYDLEDQLSITGLVLEETK
                     TYKVAHDATIVEEDGTEIRIAPLDVQYQNASIGGRLITNFAGPMNNFILGIVVFILLV
                     FLQGGMPDFSSNHVGVQENGAAAKAGLRDNDQIVAINGYKVTSWNDLTEAVDLATRDL
                     GPSQTIKVTYKSHQRLKTVAVKPQKHAKTYTIGVKASLKTGFKDKLLGGLELAWSGAF
                     TILNALKGLITGFSLNKLGGPVAMYDMSNQAAQNGLESVLSLMAMLSINLGIFNLIPI
                     PALDGGKILMNIIEAIRRKPIKQETEAYITLAGVAIMVVLMIAVTWNDIMRVFF"
BASE COUNT          405 a          321 c          261 g          411 t
ORIGIN      
        1 catttcaaca gcaccgatct tttcaaactc ttcacgcatg atggtcttga atttctcaat
       61 ggtacgattt gccagtggta aataagcata gataccagca gaaacttggc gcacataacc
      121 ggcacgcacc ataagcgcgt ggctgataac ctgggcatca cttggcattt cgcgcaaggt
      181 tgggataagc agtttacttt gtttcataga ttattccgtt ttaatacatc cccttatcct
      241 caaacccttc tggaaacacc aagtaagagt gaagcgggat tattcaataa tttgaatgtg
      301 tattcctttc attttgagta agacctcaac ccttgcaaat cttagggttg aggtcttttt
      361 cgatctttaa catgataagg tcagcttaag atgacctatc ttgattagaa aaagacgcgc
      421 atgatatcat tccatgtcac agcaatcatc aatacgacca tgatagcaac cccagctagg
      481 gtgatatagg cctctgtttc ttgcttgata ggcttgcgac gaatagcttc aatgatattc
      541 atcaagattt ttcccccatc aagtgcagga atcggaatca ggttaaagat ccctaaattg
      601 atcgaaagca ttgccataag agataagact gactctaagc cgttttgagc agcctgattg
      661 gacatgtcat acatggcaac aggtccacct aatttattga gactaaagcc agtgatcaat
      721 cctttcaaag cattcaaaat agtaaacgcc ccactccaag ctaattctag accgcctaag
      781 agcttatcct taaatcctgt tttcagactc gccttaactc ctatcgtgta tgtctttgca
      841 tgcttttgtg gtttcacagc caccgttttt aagcgctgat gtgacttgta ggtgacctta
      901 atggtctgtg acgggcctag atcccgtgtt gcaaggtcta cagcctcagt gagatcattc
      961 cagctagtca ccttataacc attaattgcg acaatttggt cattatctcg aagaccagcc
     1021 ttagctgctg ctccattttc ttgaacaccg acatgattgc tactaaaatc tggcatccca
     1081 ccttgtaaaa agaccaagag gataaaaacc acaatcccta aaataaaatt attcatggga
     1141 cctgcaaaat tggtgattaa acgtccgcca atactagcat tttgatattg aacatcaagc
     1201 ggagcaattc ttatctcagt accgtcttct tcaacaatag tagcatcgtg agcgacctta
     1261 tatgtcttgg tttcttctaa aaccaagcca gtaatactca gctgatcttc taagtcatag
     1321 cctgtaacat gcattgggag actcgttggg tctaacttac tttgagacaa gttgatgcgc
     1381 ttaacaaaac cttgctca
//
LOCUS       DAXMQE010000087         1351 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.087, whole genome shotgun sequence.
ACCESSION   DAXMQE010000087 DAXMQE010000000
VERSION     DAXMQE010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1351)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1351)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1351
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.087"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            6..>1351
                     /gene="prtF1"
                     /locus_tag="ACF4ZO_001910"
     CDS             6..>1351
                     /gene="prtF1"
                     /locus_tag="ACF4ZO_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding protein PrtF1/SfbI"
                     /protein_id="HFD5487406.1"
                     /translation="MVSSYMFVRGEKMNNKIFLNKEASFLAHTKRKRRFAVTLVGVFF
                     MLLACAGAIGFGQVAYAADEKTVPSHSSPNPEFPWYGYDAYGKEYPGYNIWTRYHDLR
                     VNLNGSRSYQVYCFNIQSNYPSQKNSFIKNWFKKIEGNGKSFVDYAHTTKLGKEELEQ
                     RLLSLLYNAYPNDANGYMKGLEHLNAITVTQYAVWHYSDNSQYQFETLWESEAKEGKI
                     SRSQVTLMREALKKLIDPNLEATAVNKIPSGYRLNIFESENEAYQNLLSAEYVPDDPP
                     KPGETSEHNPKTPELDGTPIPEDPKHPDDNLEPTLPPVMLDGEEVPEVPSESLEPALP
                     PLMPELDGQEVPEKPSIDLPIEVPRYEFNNKDQSPLAGESGETEYITEVYGNQQNPVD
                     IDKKLPNETGFSGNMVETEDTKEPEVLMGGQSESVEFTKDTQTGMSGQTTPQVETE"
BASE COUNT          451 a          228 c          294 g          378 t
ORIGIN      
        1 ataacgtggt aagctcatat atgtttgtga gaggagagaa aatgaataac aaaatatttt
       61 tgaataaaga agccagtttt ttggcacaca caaaaagaaa aaggcgattt gctgtcactt
      121 tagtgggagt cttttttatg cttttggcat gcgcgggtgc tatcggtttt ggtcaagtag
      181 cctatgctgc cgatgagaag actgtgccga gtcatagtag tccaaatcct gagtttcctt
      241 ggtacggtta tgatgcttat ggtaaggaat atcctggata taatatttgg actcgttatc
      301 atgacttgag agtaaattta aatgggagtc ggagctacca agtttattgt tttaatattc
      361 aatctaatta tcctagccaa aaaaatagtt tcataaaaaa ttggtttaaa aaaattgagg
      421 gaaatggcaa atcctttgta gattatgctc acactactaa actaggtaaa gaagagttgg
      481 agcagaggct cttaagttta ctgtataatg cgtatcccaa cgatgctaat ggttatatga
      541 aaggactgga gcatttaaat gctattactg taacacaata tgcagtttgg cattactcag
      601 ataattcaca atatcaattt gagacattat gggagtctga ggcgaaagaa ggtaagatta
      661 gtaggtcaca agttacttta atgcgtgagg cattgaaaaa actaattgat cccaatttag
      721 aagctactgc agttaataaa atcccatcag gctatcgttt aaatatcttt gagtctgaaa
      781 atgaagctta ccaaaatctt ttaagtgctg aatatgtacc tgatgatccc cctaaacctg
      841 gtgagacgtc agaacataat cctaaaactc ccgagttgga tggcactcca attcccgagg
      901 acccaaaaca tccagatgat aatttagaac ctacattgcc gccagtgatg ctagatggtg
      961 aagaagtccc agaagttcca agcgagagct tagagcctgc gcttccccca ttaatgccag
     1021 agttagatgg tcaagaagtc cctgaaaaac ctagtattga cttacctatt gaagttcctc
     1081 gttatgagtt taacaataaa gaccaatcac ctctagcggg tgagtctggt gagacggagt
     1141 atattaccga agtctatgga aatcaacaga accctgttga tattgataaa aaacttccga
     1201 atgaaacagg tttttcagga aatatggttg agacagaaga tacgaaagag ccagaagtgt
     1261 tgatgggagg ccaaagtgag tctgttgaat ttactaaaga cactcaaaca ggcatgagtg
     1321 gtcaaacaac tcctcaggtt gagacagaag a
//
LOCUS       DAXMQE010000088         1346 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.088, whole genome shotgun sequence.
ACCESSION   DAXMQE010000088 DAXMQE010000000
VERSION     DAXMQE010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1346)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1346)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1346
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.088"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            93..362
                     /locus_tag="ACF4ZO_001911"
     CDS             93..362
                     /locus_tag="ACF4ZO_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5487407.1"
                     /translation="MKKPNRYPYSKSKFNGCIYQLHSASFKDEQYVEDLKSCGIHYQI
                     TKIGYFPDIFIKIDNLEQLQILIDKTGHDLILSKDQIWIYDDYME"
     gene            372..785
                     /locus_tag="ACF4ZO_001912"
     CDS             372..785
                     /locus_tag="ACF4ZO_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YopX family protein"
                     /protein_id="HFD5487408.1"
                     /translation="MIPKFRAFNKKTKKMYSIDGFKSSERKIYRCSLADDEFRSGRLE
                     TFHFVEDNLDDYVLMQSTGLFDKNGVEIFEGDVVKLQYTITSDLEFFKVNQFRGGSWR
                     IDNRRRGSDLWLRNEDCEVIGNIHENQDLIESVEE"
     gene            782..952
                     /locus_tag="ACF4ZO_001913"
     CDS             782..952
                     /locus_tag="ACF4ZO_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5487409.1"
                     /translation="MRKYIEFKDEWKSAADHLNDFIDNNKYAKVTVVGYQVVQISPYG
                     RDATYILAEVEE"
     gene            949..1113
                     /locus_tag="ACF4ZO_001914"
     CDS             949..1113
                     /locus_tag="ACF4ZO_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000159368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5487410.1"
                     /translation="MTKEEVIAFLTEQRDLRLFGYEQGKDDLSDFEKWQLAQADMYLK
                     VIEWIESVKE"
     gene            1110..>1346
                     /locus_tag="ACF4ZO_001915"
     CDS             1110..>1346
                     /locus_tag="ACF4ZO_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5487411.1"
                     /translation="MTTDELLQNLRDDLNKIINVLKNDWKALLFLAIAIFGMMVIVSY
                     FSYRDARQYYESQITGLRTQLSRTQKQLKRASEQN"
BASE COUNT          486 a          198 c          292 g          370 t
ORIGIN      
        1 cttttgcggt atcacgctaa aaatggtgtt gaagacctta aaaaagcacg gcagaacctt
       61 gattggttaa tcgaaaagtt ggaggaagtg gaatgaagaa accaaatcgc tatccgtaca
      121 gtaaatcaaa atttaatggt tgtatttacc agttgcattc agccagcttt aaagatgaac
      181 aatatgttga agatttaaaa tcatgcggca tacattatca aattacaaaa attggttatt
      241 ttcctgatat ttttataaaa attgataatc tcgaacaatt acaaatatta atagataaaa
      301 caggacacga tttaatactt agtaaagacc aaatttggat ttatgatgac tatatggaat
      361 gaggagtaat aatgatacca aaatttaggg catttaataa aaagaccaaa aaaatgtata
      421 gcattgatgg ctttaaatca agtgaacgca aaatatacag atgcagctta gctgatgacg
      481 agtttcgctc tggtcgctta gagacgtttc attttgtcga ggataacctt gacgattatg
      541 tcctcatgca gtccacaggg ctatttgata aaaacggtgt tgagattttt gagggagacg
      601 tcgtgaaatt acaatataca attactagtg atttagaatt ttttaaagtg aatcaattca
      661 gaggtggttc ttggcgcatt gacaatagac gacgcggatc agatttgtgg ttaagaaacg
      721 aggactgcga agttatcggt aacatacacg aaaaccaaga cttaatagaa agcgtggaag
      781 aatgagaaaa tatattgaat ttaaggacga atggaaaagt gcagcagacc acctaaacga
      841 ttttatcgac aataacaagt acgcaaaagt gacagttgtt ggttatcaag tcgtacaaat
      901 ttctccttac gggagagatg cgacttatat tttggcagag gtggaagaat gactaaagaa
      961 gaagtaattg catttctgac cgaacagcgt gatttgcggc tttttggata tgagcagggg
     1021 aaagacgacc tgtctgactt tgagaagtgg cagttagccc aagctgacat gtacttaaag
     1081 gtaattgagt ggatagaaag cgtgaaagaa tgacaacaga tgaattattg caaaatttac
     1141 gtgatgactt gaataaaata attaatgtcc taaaaaacga ttggaaagca ctattgtttc
     1201 ttgcaatcgc aatatttggg atgatggtaa tcgtgtcgta ttttagctat cgcgacgcac
     1261 gacaatatta cgagtcgcaa atcacaggac tacgtacaca gctaagcagg acacaaaagc
     1321 agcttaaacg tgctagcgag caaaat
//
LOCUS       DAXMQE010000089         1249 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.089, whole genome shotgun sequence.
ACCESSION   DAXMQE010000089 DAXMQE010000000
VERSION     DAXMQE010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1249)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1249)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1249
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.089"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            <1..733
                     /locus_tag="ACF4ZO_001916"
     CDS             <1..733
                     /locus_tag="ACF4ZO_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008088464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HFD5487412.1"
                     /translation="FDEAMAEIEKAKKAQEEINQRTDKELEEFRATLKNLALPEEAIK
                     KITEAIKVDDIPSIKQSFDDLKNRVSETSEESRLTAEILGNNGKTRYNKNLLVGNPNR
                     VKKIDEDYIEVEANDGGFKRGETYTISFSQTCEPLKKVAITLIQANNKGVKLVLTPTK
                     AKMEPETFTLIKDTEVINVYPLSYKGVLTGDWYKSKQIDLTVSEAQELALEMAYKEVV
                     DGNNADLVLDWAENPDIIFDGNGGI"
     gene            733..>1249
                     /locus_tag="ACF4ZO_001917"
     CDS             733..>1249
                     /locus_tag="ACF4ZO_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronoglucosaminidase"
                     /protein_id="HFD5487413.1"
                     /translation="MSKEVASARIQHRGMTTQGWESSSDILMEREIGIDMTTGYPKVG
                     DGKNKFKDLKDLRGPMGPQGPTGERGPIGPTGPIGKTGTTDYNQLQNKPNLDAFAQKK
                     ETNSKITKLESSKADKSAVYSKAESKIELDKKLSLTGGIVTGQLQFKPNKSGIKPSSS
                     VGGAINIDMSKS"
BASE COUNT          464 a          225 c          280 g          280 t
ORIGIN      
        1 ctttgacgag gcaatggctg aaatcgaaaa agccaaaaaa gcgcaagaag aaatcaacca
       61 gcgcaccgat aaagagcttg aagaatttag agctaccctc aaaaacctag cgttaccaga
      121 ggaagcgatt aaaaaaatca cagaggctat caaagttgat gacatcccgt ctattaaaca
      181 aagctttgat gacctcaaaa atagagtgag tgagacaagc gaagaatctc gtttaactgc
      241 cgaaatttta ggaaataacg gtaagacccg ctataacaaa aatttgctgg tcggcaaccc
      301 taatcgtgtt aaaaaaattg atgaggatta catcgaggta gaagccaacg acggtggttt
      361 taagcgtggc gagacctaca caatcagctt tagtcagaca tgtgagccgc tcaaaaaagt
      421 ggctatcacg ctgatccaag ctaataataa gggagttaaa ctggtactga cacctactaa
      481 ggcaaaaatg gagcctgaga cttttactct aattaaggac acagaggtca tcaacgtcta
      541 tcctttgagc tataaaggcg ttttaacagg cgactggtat aaatctaagc aaatagattt
      601 aaccgtgtca gaggcgcagg aattagctct tgagatggct tataaagagg ttgtggacgg
      661 caataatgct gatttagttt tggattgggc ggaaaaccca gatattattt ttgacggaaa
      721 cggaggtatt taatgtcaaa agaagttgca tcagcaagga tacagcatag aggcatgacc
      781 acacaagggt gggaatcaag ttccgatatt ttaatggagc gagaaattgg aattgacatg
      841 actacgggtt acccaaaagt tggcgatggt aaaaataagt tcaaggactt aaaagacttg
      901 cgtggtccta tgggacctca aggtcctaca ggagaaagag gcccaattgg cccaacaggt
      961 ccgattggca aaactggaac gacagattat aatcaactcc aaaataaacc aaatctagat
     1021 gcgtttgcac aaaaaaaaga aactaatagt aaaatcacca aattagaatc aagcaaagca
     1081 gataaaagcg ctgtttactc aaaagcagag tcaaaaatag agctagacaa aaaattgagt
     1141 ttgacaggcg gcatagtgac aggacaacta cagtttaaac ctaataaaag tggtattaaa
     1201 ccctcatctt ccgtaggagg agcgattaac attgatatgt ctaaatcag
//
LOCUS       DAXMQE010000090         1232 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.090, whole genome shotgun sequence.
ACCESSION   DAXMQE010000090 DAXMQE010000000
VERSION     DAXMQE010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1232)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1232)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1232
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.090"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            355..1092
                     /locus_tag="ACF4ZO_001918"
     CDS             355..1092
                     /locus_tag="ACF4ZO_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HFD5487414.1"
                     /translation="MGKEIKVKYFLRRSAFGLVAVSASVLVGSTVSAVDSPIEQPRII
                     PNGRTLTNLLGNAPEKLALRNEERAIDELKKQAIEDKEATTAIEAASSDALEALADQA
                     DALQSEEAAVVQSDTAASDALEALADQTDALQSEEAAVVKADTAASDALEALADQTDA
                     VQSEEASVVKADTAASDAWEKAATPTALDVKKTKDTTPVVKKEERQNVNTLPTTGEES
                     NPFFTAAALAIMVSTGALVVSSKCKEN"
BASE COUNT          458 a          199 c          219 g          356 t
ORIGIN      
        1 gaagctaacg cttctctttt ttatattaca tgtgcttagg ctaataatac ttaggtgcat
       61 actttgttgc attttatggc tttttaactg tcataaaaaa tataaaaatg atatcactaa
      121 ctaatattat taattttaat gctaaaataa tgagttgacg gtagtaaagt gataaataaa
      181 cactccttaa aatcttattt tattaatttt tttaaaaaat aatatataaa ttagctaata
      241 aacttgattt tatgcaatta atctgtataa taaaagatgg aattattaat tataatttcc
      301 aaattatcgg taatttaata tgctaatgca tataaaaata aaaaaggaga aacaatggga
      361 aaagaaataa aagtgaaata ctttttgcgt agatcagctt ttggattagt tgcggtgtca
      421 gcatcagtat tagtcggttc aacagtatct gctgttgact cacctatcga acagcctcga
      481 attattccaa atggcagaac cttaactaat cttcttggca atgctccaga aaaactggca
      541 ttacgtaatg aagaaagagc cattgatgaa ttaaaaaaac aagctattga ggataaagaa
      601 gctacgacag ctatagaagc agcaagttca gatgccttag aagcattagc ggatcaagca
      661 gacgctttac aatcagaaga agctgcagta gttcaatcag ataccgctgc tagtgatgcc
      721 ttagaagcat tggcggatca aacagacgct ttacaatcag aagaagctgc ggttgttaaa
      781 gcggataccg ctgctagtga cgccttagaa gcattggcgg atcaaacaga cgctgtacaa
      841 tcagaagaag cttcagttgt taaagcagat accgctgcta gtgacgcctg ggaaaaagca
      901 gcaactccaa ccgctttaga tgttaagaaa actaaagata caacacctgt agttaaaaaa
      961 gaagaaagac aaaacgttaa tacccttcct acaactggtg aagagtctaa cccattcttt
     1021 acagctgctg cgcttgcaat aatggtaagt acaggtgcgt tagttgtaag ttcaaagtgc
     1081 aaagaaaatt agttgctatt tgttctagca aatgaaacaa gagaatcgaa agattctctt
     1141 gttctgatat ttaaaaatgc tacagtttat aataccttga aagactaaat gttctcaaac
     1201 tcattagaac aagctttaat aaaactaacc ca
//
LOCUS       DAXMQE010000091         1024 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.091, whole genome shotgun sequence.
ACCESSION   DAXMQE010000091 DAXMQE010000000
VERSION     DAXMQE010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1024)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1024)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1024
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.091"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            <1..442
                     /locus_tag="ACF4ZO_001919"
     CDS             <1..442
                     /locus_tag="ACF4ZO_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5487415.1"
                     /translation="VGDPNRVKKIDEDFIEIEANDGGFKRGETYTISFSQTCELLQKV
                     AVTLTQANNKGVKLVLTPTKAKMESQTFDLTKDKEVISVYPFSYTAVLTGDWYKSKQI
                     DLNASEVRELALEMDYKEIADAKGATITGAWSDSPQIILDGGKK"
     gene            439..1024
                     /locus_tag="ACF4ZO_001920"
                     /pseudo
     CDS             439..1024
                     /locus_tag="ACF4ZO_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_115223326.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronoglucosaminidase"
BASE COUNT          357 a          176 c          237 g          254 t
ORIGIN      
        1 ggttggcgac cctaaccgtg ttaaaaaaat tgatgaggat tttatcgaga tagaggccaa
       61 tgacggtggt tttaaacgcg gtgagacata cacgataagc tttagtcaga cttgtgagct
      121 gctccaaaaa gtggctgtca cgctgacaca ggctaacaac aagggagtta agttagtgct
      181 gacaccaact aaagcaaaaa tggagtcgca gacctttgac ctcactaaag ataaagaggt
      241 tatcagtgtt tatccgttta gctacacggc tgttttaact ggcgactggt ataaatctaa
      301 gcagatagat ttaaacgcgt cggaggtgag ggaattggct ctggagatgg attataaaga
      361 gattgcagat gccaaaggtg caactatcac aggggcatgg tcagacagtc cacaaattat
      421 attagacgga ggtaaaaaat gagtgaaaat ataccgctgc gagtccaatt taagcggatg
      481 actgctagcg agtgggctcg tagtgatgtc atcttactgg agagtgagat aggctttgag
      541 acagacacag gatatgcgaa gtttggtgat ggtaaaaacc gatttagtaa gcttaagtac
      601 cttaataaac cagatctaga tgcgtttgca caaaaaaaaa gaaactgata ataaaatcgc
      661 caaattagaa tcaattaaag cagacaaaga cactgtttac ttaaaagcag agtcaaaaaa
      721 agagctagac aaaaaaatga atttgacagg cggcacaatg acaggacaac tacagtttaa
      781 acctaatagt catattaagc actcatcttc tacaggagga gcgattaaca ttgatatgtc
      841 taaatcagca ggtgctgcta tggtgatgta tacaaataaa gatactactg atggaccatt
      901 gatgatttta cgctctgaca aagatacgtt tgatcagtca gctcaatttg tggattacag
      961 cggtaagact aatgctgtaa atattgtaat gcgccagcca agcacaccta atttttcctc
     1021 agca
//
LOCUS       DAXMQE010000092          984 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.092, whole genome shotgun sequence.
ACCESSION   DAXMQE010000092 DAXMQE010000000
VERSION     DAXMQE010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 984)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 984)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..984
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.092"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            80..>984
                     /locus_tag="ACF4ZO_001921"
     CDS             80..>984
                     /locus_tag="ACF4ZO_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30-like element IS1239 family transposase"
                     /protein_id="HFD5487416.1"
                     /translation="MQDYYTPKGKQLTIHERRQIQRWKLEGRSNREIARLLGKAPQTI
                     HNEIKRGLVRQQVRKGKFEAVYSAQHAQLVYQENRKRSVRPIRQRKQDREAIEHYMRQ
                     NYSPEMIVKAKGVQVPVSTIYYWIHHGKLSLGKEAMLYPRKAKQARKHASPYFKPAGK
                     SIEQRPDSINQRLEAGHYEIDTVILTRAKNQCLLTLTDRKTRHQLIRLIPDKSAQAVN
                     KALTGILKDYTVNSITADNGTEFSRLSDVFPASDIYYAHPYASWERGTNENHNRLIRR
                     CLPKGTKTTTPKEVAAIEHWINHYP"
BASE COUNT          325 a          219 c          204 g          236 t
ORIGIN      
        1 agccactttt aaggtatgaa aaaagcacct ctaagaggta tacttgtagt tcaccacaaa
       61 cacaaggaaa ctcaaaaaga tgcaagatta ttatacacca aaaggcaaac aattgacaat
      121 ccatgagcgt cggcaaattc aacgctggaa gctggaaggt cgctctaatc gtgaaattgc
      181 tcgcttacta ggtaaggccc cccagaccat tcataatgaa atcaagcgag gattggttag
      241 gcaacaggtt cgtaaaggaa agtttgaagc cgtttattct gctcaacatg ctcagttggt
      301 ctatcaagaa aatcgcaagc gttctgttag acccattaga cagcgtaagc aagataggga
      361 ggctattgaa cactacatgc gtcagaacta ttcccctgag atgatagtta aagctaaggg
      421 agttcaagtc cctgtatcta ccatctatta ctggattcat catgggaaat tgagtcttgg
      481 taaggaggct atgctttatc cgagaaaggc taagcaggct agaaaacatg ccagtcctta
      541 ttttaaaccc gcaggaaaga gtattgaaca acgcccagat agcattaacc aacgtcttga
      601 agctgggcat tatgagattg atacagtcat tctgacgagg gctaaaaatc aatgcttact
      661 caccctaacg gacaggaaaa cacgtcatca gctgattcga ttaataccgg ataagtctgc
      721 tcaagctgtc aataaagctc ttacggggat tctaaaagac tacaccgtca actctatcac
      781 ggcagacaac gggacagaat tttctcgctt atcagatgtc tttccagcaa gtgacatcta
      841 ctatgcccat ccctatgcgt catgggagag aggcactaac gaaaaccata atcgcctgat
      901 tcgcagatgt ctccctaaag gtaccaaaac aacgacccct aaagaagtcg ctgctattga
      961 acattggatc aatcattatc ctaa
//
LOCUS       DAXMQE010000093          894 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.093, whole genome shotgun sequence.
ACCESSION   DAXMQE010000093 DAXMQE010000000
VERSION     DAXMQE010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 894)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 894)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..894
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.093"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            161..445
                     /locus_tag="ACF4ZO_001922"
     CDS             161..445
                     /locus_tag="ACF4ZO_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3310 domain-containing protein"
                     /protein_id="HFD5487417.1"
                     /translation="MLTEDTFKKIEELEAACQDTTDNIKKPSHYQGRHGMEAIDVVKN
                     FGACPEYEEGFYWGNAVKYLLRYHAKNGIEDLKKARQNLDWLIEKLEVDE"
     gene            442..855
                     /locus_tag="ACF4ZO_001923"
     CDS             442..855
                     /locus_tag="ACF4ZO_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YopX family protein"
                     /protein_id="HFD5487418.1"
                     /translation="MIPKIRGFNKKTKKMYSIDGFKASERKIYRCSLADDEFRSGRLE
                     TFHFVEDNLDDYILMQSTGLKDKNGVEIFEGDVVKLQYTITSDLEFFKVNQFRGGSWR
                     IDNRRRGSDLWLRNEDCEVIGNIYQNSDLIESVEE"
BASE COUNT          319 a          118 c          216 g          241 t
ORIGIN      
        1 tgttaatagc tcacagatac aaaataaaga cgtctgatga cgttttagcg gaaaggatag
       61 gtatttatac ttggaagcta aaagcgctct taaaacgcag aatattgcca aataagagtg
      121 agtgtaaatt gattatagat tttttgagag aggtggagag atgctgacgg aagatacgtt
      181 taaaaaaatt gaggaacttg aagctgcttg tcaggatacg acagataaca ttaaaaaacc
      241 atcacactat caaggaaggc atggcatgga agcaatcgat gtggttaaaa acttcggtgc
      301 ttgtccagag tatgaggagg gtttttattg gggcaatgct gttaagtatt tactacggta
      361 tcatgctaaa aatggcattg aagacctcaa aaaagcacgg cagaaccttg attggttaat
      421 cgaaaagttg gaggtagacg aatgatacca aaaattaggg ggtttaataa aaagaccaaa
      481 aagatgtata gcattgatgg ctttaaagca agtgaacgca aaatatacag atgcagctta
      541 gcagatgatg agtttcgctc tggtcgctta gagacgtttc attttgtcga ggataacctt
      601 gatgattata ttctcatgca atcaacaggc ctaaaagata aaaacggtgt tgagattttt
      661 gagggagacg tcgtgaaatt acaatataca attactagtg atttagaatt ttttaaagtg
      721 aatcaattca gaggtggttc ttggcgaatt gacaatagac gacgcggatc agatttgtgg
      781 ttaagaaacg aggactgcga agttatcggg aatatatatc agaacagcga cctgatagaa
      841 agtgtggaag aatgacaaca gatgaattat tgcaaaattt acgtgatgac ttga
//
LOCUS       DAXMQE010000094          852 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.094, whole genome shotgun sequence.
ACCESSION   DAXMQE010000094 DAXMQE010000000
VERSION     DAXMQE010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 852)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 852)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..852
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.094"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            <1..338
                     /locus_tag="ACF4ZO_001924"
     CDS             <1..338
                     /locus_tag="ACF4ZO_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HFD5487419.1"
                     /translation="NGEMGPKMYPELAWGANPDSINGLKSSVNTTVGAGADEAESKDL
                     VIIGDFESMFKWGYAKQIPMEIIKYGDPDNSGKDLKGYNQIYLRAEAYIGWGILDAKS
                     FARVTKGEV"
     gene            338..538
                     /locus_tag="ACF4ZO_001925"
     CDS             338..538
                     /locus_tag="ACF4ZO_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5487420.1"
                     /translation="MLYVNSKTGASFYSSVPVCGGDWTLVEQQTGEKAKTVAEIKRQL
                     DAAGIKYSSKAKKPELEALLPG"
     gene            548..>852
                     /locus_tag="ACF4ZO_001926"
     CDS             548..>852
                     /locus_tag="ACF4ZO_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage Gp19/Gp15/Gp42 family protein"
                     /protein_id="HFD5487421.1"
                     /translation="MGNFATTDDVILLWRPLSVDELKRANALLKVVSDTLRMEADKVG
                     KDLDKTMVDKPYFVNVIKSVTVDIVARTLMTSTQGEPMSQESQSALGYTWSGTYLVPG
                     "
BASE COUNT          265 a          139 c          210 g          238 t
ORIGIN      
        1 ccaatgggga gatggggcct aaaatgtacc ctgaacttgc ttggggagcg aatccagata
       61 gcatcaatgg cttgaaatcg tccgtcaata ctactgttgg tgctggagct gatgaagcag
      121 aatccaaaga tttagtaatt attggcgatt ttgaaagcat gtttaagtgg ggttatgcaa
      181 aacaaattcc aatggaaatc attaaatacg gtgatcctga taattcgggg aaagacctta
      241 aagggtataa ccaaatttac ttacgtgctg aggcgtatat cggctggggt attttggacg
      301 ctaagagctt tgctcgtgtc actaaaggag aagtataatg ttatacgtta acagtaagac
      361 tggagctagt ttttatagct ccgtccctgt ttgtggtgga gattggactt tggttgaaca
      421 gcagacaggc gaaaaagcaa aaacagtagc agaaattaaa cgtcagttag atgctgctgg
      481 gataaaatat agctctaaag ctaagaaacc tgaattagag gcactcttgc ctggttagga
      541 ggtaaaagtg ggcaattttg caacaacaga tgacgtcatt ttgttatggc gtcccttatc
      601 tgttgacgaa ttgaaacgtg caaatgcact cttgaaagtc gtatcagata cattaagaat
      661 ggaagctgac aaagttggca aagacttaga taaaacgatg gttgataagc cttattttgt
      721 taatgttatt aaatcggtta cggttgacat tgtagctaga acactcatga catctactca
      781 aggtgaaccg atgtcgcaag aaagtcaatc ggcacttggc tacacttggt ctggaactta
      841 tttggttcca gg
//
LOCUS       DAXMQE010000095          837 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.095, whole genome shotgun sequence.
ACCESSION   DAXMQE010000095 DAXMQE010000000
VERSION     DAXMQE010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 837)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 837)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..837
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.095"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            complement(268..723)
                     /locus_tag="ACF4ZO_001927"
     CDS             complement(268..723)
                     /locus_tag="ACF4ZO_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HFD5487422.1"
                     /translation="MIIDLTSLIHLFGDLVRTVEIHVFTLFVCFDIITGLTKGITNKR
                     ANSTKGLSGIIKHFLVVLLVYTVYPYLILLGAKPLAVAFVLFFIACYGISIVENWGQL
                     GLPMPSFVRSFFEKLKRDTDQFDIATIKIDKTGVKLEAPQVDLKQKEEE"
BASE COUNT          265 a          178 c          143 g          251 t
ORIGIN      
        1 attgccccaa agggcaatgc taaaatattt tgtcgtgatc cagtttggca agtccacgca
       61 ctgcgtaccg taaacattat caagatcaac tccttggcca gcatccgcta atccttttgc
      121 aaaagacaag acttcgtcta aagttgccat atcagttact tcctttcttc aaaaaatggg
      181 cttaaaatca aagcaatcac agataatggc acatacagta ttgcgattgc tataactaat
      241 gctaatcgtg tgactgcttg tctcatgcta ctcctcttct ttttgtttta aatcaacttg
      301 tggcgcctcg agtttaacac ctgttttatc aattttgatt gtcgcaatat caaactggtc
      361 tgtatcacgt ttgagctttt cgaaaaatga tctgacaaaa cttggcattg gcaaacctag
      421 ttgtccccaa ttttctacga ttgaaatacc ataacaggcg ataaaaaata ggacaaaggc
      481 gactgctaaa ggcttagctc cgagcaagat taggtaagga tagacagtat agactaacaa
      541 cacaactaaa aagtgtttaa taatgccaga tagccctttt gtactgtttg ctctcttatt
      601 agtaatacct tttgtcagtc ctgtaataat gtcaaaacag acaaaaagcg taaaaacgtg
      661 gatttcgacg gtacgaacta aatccccgaa aaggtgaata agacttgtta aatcaataat
      721 catctaacca cctcaatcct gcttaactaa gtccgcatac ttaatgactg tgactttatc
      781 ctctgattct aagtcctcta aggtctgtgt ctcataagta aacgagtcgt tgacatg
//
LOCUS       DAXMQE010000096          808 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.096, whole genome shotgun sequence.
ACCESSION   DAXMQE010000096 DAXMQE010000000
VERSION     DAXMQE010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 808)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 808)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..808
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.096"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            5..78
                     /locus_tag="ACF4ZO_001928"
     tRNA            5..78
                     /locus_tag="ACF4ZO_001928"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:39..41,aa:Asn,seq:gtt)
     gene            147..220
                     /locus_tag="ACF4ZO_001929"
     tRNA            147..220
                     /locus_tag="ACF4ZO_001929"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:181..183,aa:Arg,seq:acg)
     gene            246..797
                     /locus_tag="ACF4ZO_001930"
     CDS             246..797
                     /locus_tag="ACF4ZO_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HFD5487423.1"
                     /translation="MSCCFFVVLFILGIVKKKRRLKMSIETRAAFEKVKPIILKLKRH
                     YYIQLWDRDDWLQEGHIILLQLLERYPELIEEEERLYRYFKTKFSSYLKDLLRRQESQ
                     KRQFHKLAYEEIGEVAHAIPSRGLWLDDYVAYQEVIASLENQLNSQERMQFQALIRGE
                     RFKGRRALLRKISPYFKEFAQQL"
BASE COUNT          258 a          130 c          191 g          229 t
ORIGIN      
        1 tttatccgcc atagctcagt tggtagtagc gcatgactgt taatcatgat gtcgtaggtt
       61 cgagtcctac tggcggagta gaaagaggta ggaagcgtcc tatctttttt tgcattttag
      121 agaagagtgt ggcaagatat gcgttggcac ccttagctca actggataga gtacctgact
      181 acgaatcagg cggttagagg ttcgactcct ctagggtgca taatgaaaaa aacaacagga
      241 cactaatgtc ctgttgtttt tttgtggttc tctttatact agggatagtt aaaaagaaaa
      301 ggagactcaa aatgtcgata gagacaagag cagcgtttga aaaagttaag cccattattt
      361 tgaaattaaa gcgacactat tatattcaat tgtgggatag agatgactgg ttacaagaag
      421 gacatattat cttattacag ttactagaaa ggtacccaga gttaattgag gaagaagagc
      481 gtttatatcg ctattttaaa acaaaatttt catcttattt gaaagattta ttacgccgtc
      541 aagaaagtca aaagcgtcag ttccataagt tagcatatga agagataggg gaggttgcac
      601 atgccattcc atcgagaggg ttatggctag acgactatgt ggcttatcaa gaggtaatag
      661 ctagcttaga gaaccaatta aattcgcaag agcgtatgca gtttcaagca cttatcaggg
      721 gcgaacgttt caagggaaga cgtgctctac ttaggaagat cagtccctat tttaaggaat
      781 ttgcacagca gttgtaagca agacctat
//
LOCUS       DAXMQE010000097          798 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.097, whole genome shotgun sequence.
ACCESSION   DAXMQE010000097 DAXMQE010000000
VERSION     DAXMQE010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 798)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 798)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..798
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.097"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            <1..409
                     /locus_tag="ACF4ZO_001931"
     CDS             <1..409
                     /locus_tag="ACF4ZO_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF1617 family protein"
                     /protein_id="HFD5487424.1"
                     /translation="KDLNTLYRVLDKIKITNMRANRGRAKLLAKVEGKLSEYAKDEVD
                     IIDQYVAKNDDGKWITDDKGNPKIEDTSKLAELNDFLDELASEPIVIKGGEYSKRFID
                     FLEYLVESEDEFTSEEIVLIDNILEQFEESKGE"
     gene            412..>798
                     /locus_tag="ACF4ZO_001932"
     CDS             412..>798
                     /locus_tag="ACF4ZO_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1366 domain-containing protein"
                     /protein_id="HFD5487425.1"
                     /translation="MRNWKVIGKYPQYDSTGAVASTHIIITAEDGSVISQPIKQDLTS
                     TNDTEIIKATLEEFKKSEYVEIAMSEAVQKVDDLEKISQETAKTAKTAQTAAGLAKVS
                     AERTQRMINLQTIHVLTSGGKVEPDIY"
BASE COUNT          295 a          152 c          170 g          181 t
ORIGIN      
        1 caaagattta aacacactat atcgtgtact agacaaaatc aaaatcacga acatgcgagc
       61 aaaccgcgga cgtgctaagc tacttgcaaa agtcgagggc aagctaagcg agtatgccaa
      121 agatgaggtt gatattattg accagtatgt tgcaaaaaat gacgatggca agtggattac
      181 agatgacaaa ggtaatccaa aaattgagga cacctcaaag ttagctgagc ttaacgactt
      241 tttagacgag ttagcaagcg agcctatcgt catcaaaggt ggcgagtact ctaagcgctt
      301 tatcgatttt ttggaatatt tagtcgaatc tgaagatgag tttacatcag aggaaatcgt
      361 cttaattgat aatattttgg aacaatttga agaaagtaaa ggagaataat tatgcgcaat
      421 tggaaagtaa tagggaaata tccacaatat gacagcacag gagcagtcgc aagcacacac
      481 atcattatca cagcagaaga tggctcagtc atctctcaac caatcaagca ggacttaacc
      541 tcaactaatg acacagagat tatcaaagct actttggaag aatttaaaaa atccgaatat
      601 gtcgaaatcg ctatgagcga agcagtccaa aaagttgatg acttggaaaa aatctcacaa
      661 gaaaccgcta agactgctaa aacagcccaa acagccgctg gactagctaa ggtgtccgca
      721 gagcgtacac agcggatgat taacttgcaa accatccacg tattgacaag tggtgggaaa
      781 gttgaacccg atatctac
//
LOCUS       DAXMQE010000098          789 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.098, whole genome shotgun sequence.
ACCESSION   DAXMQE010000098 DAXMQE010000000
VERSION     DAXMQE010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 789)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 789)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..789
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.098"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            <1..472
                     /locus_tag="ACF4ZO_001933"
     CDS             <1..472
                     /locus_tag="ACF4ZO_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hyaluronoglucosaminidase"
                     /protein_id="HFD5487426.1"
                     /translation="AVNIVMRQPSEPNFSSALNITSANEGGSAMQIRGIERKLGTLKI
                     THENPSANAKYDENAAALSIDIVGKRGASGNGTAAQGIFINSSAGTTGKMLRIRNKNK
                     DKFYVNPDGGFHSYASSTVAGNLTVNDPISEKHAATKDYVDKAISELKKLIPKK"
     gene            487..>789
                     /locus_tag="ACF4ZO_001934"
     CDS             487..>789
                     /locus_tag="ACF4ZO_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gp58-like family protein"
                     /protein_id="HFD5487427.1"
                     /translation="MSRDPTLLIDESNLTIGSDGRAYYTFTADGDTKSVKIANNKCIG
                     TTRFNQLMIERGDKPTNYVAPVVVEGTGNPTGLFKDLKELNLELTDTANSQLWAKIK"
BASE COUNT          285 a          154 c          164 g          186 t
ORIGIN      
        1 tgctgtaaat attgtaatgc gccagccaag cgaacctaat ttttcctccg cacttaatat
       61 aacaagtgct aacgagggcg gtagtgcgat gcaaattaga ggtatcgaaa gaaaattggg
      121 aacgctcaaa atcacacatg aaaacccaag cgctaacgca aaatacgatg aaaacgctgc
      181 agcgttatct attgatatcg ttggaaaacg gggagccagt ggaaatggta ctgctgccca
      241 aggcattttc atcaattcgt ccgcaggcac aactggtaaa atgctcagaa tcagaaataa
      301 aaataaagac aaattttatg taaatccaga tggcggcttt cactcatatg caagttcaac
      361 tgtagctggt aatctaacag ttaacgatcc aatatctgaa aaacatgctg cgactaaaga
      421 ttacgtagat aaagcaattt ctgagttaaa aaaactcata ccaaaaaaat agattaagga
      481 ggataaatga gcagagaccc aacactttta atagacgagt caaatttaac aatcggctca
      541 gatggacgtg cttattatac atttacggct gatggtgaca caaaaagcgt taaaatagcc
      601 aataacaaat gtatcggtac aactcgcttt aaccagctca tgattgagcg aggagataag
      661 ccaactaatt acgtggcgcc cgtggttgtc gaggggacag gtaatccgac tggactattt
      721 aaagacctca aagagcttaa tttagagctg acagatactg ctaactctca gctctgggca
      781 aaaatcaag
//
LOCUS       DAXMQE010000099          712 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.099, whole genome shotgun sequence.
ACCESSION   DAXMQE010000099 DAXMQE010000000
VERSION     DAXMQE010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 712)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 712)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..712
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.099"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            complement(4..77)
                     /locus_tag="ACF4ZO_001935"
     tRNA            complement(4..77)
                     /locus_tag="ACF4ZO_001935"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(41..43),aa:Pro,seq:tgg)
     gene            complement(84..157)
                     /locus_tag="ACF4ZO_001936"
     tRNA            complement(84..157)
                     /locus_tag="ACF4ZO_001936"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(121..123),aa:Arg,seq:acg)
     gene            complement(174..258)
                     /locus_tag="ACF4ZO_001937"
     tRNA            complement(174..258)
                     /locus_tag="ACF4ZO_001937"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(222..224),aa:Leu,seq:taa)
     gene            complement(267..338)
                     /locus_tag="ACF4ZO_001938"
     tRNA            complement(267..338)
                     /locus_tag="ACF4ZO_001938"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(304..306),aa:Gly,seq:gcc)
     gene            complement(351..423)
                     /locus_tag="ACF4ZO_001939"
     tRNA            complement(351..423)
                     /locus_tag="ACF4ZO_001939"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(388..390),aa:Thr,seq:tgt)
     gene            complement(434..515)
                     /locus_tag="ACF4ZO_001940"
     tRNA            complement(434..515)
                     /locus_tag="ACF4ZO_001940"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(479..481),aa:Leu,seq:tag)
     gene            complement(521..593)
                     /locus_tag="ACF4ZO_001941"
     tRNA            complement(521..593)
                     /locus_tag="ACF4ZO_001941"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(558..560),aa:Lys,seq:ttt)
     gene            complement(625..697)
                     /locus_tag="ACF4ZO_001942"
     tRNA            complement(625..697)
                     /locus_tag="ACF4ZO_001942"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(662..664),aa:Asp,seq:gtc)
BASE COUNT          189 a          209 c          152 g          162 t
ORIGIN      
        1 taatcgggaa gacaggattc gaacctgcga caccttggtc ccaaaccaag tactctacca
       61 agctgagcta cttcccgaac tgatgcaccc tagaggagtc gaacctctaa ccgcctgatt
      121 cgtagtcagg tactctatcc agttgagcta agggtgctat ttcaaaaaat taatgccgag
      181 gaccggaatc gaaccggtac gatgtaaacc atcgcaggat tttaagtcct gtgcgtctgc
      241 cagttccgcc accccggctc ctcaaaagcg aacgacggga ttcgaacccg cgacccccac
      301 cttggcaagg tgatgttcta ccactgaact acgttcgcaa ctaatctcaa tgccggctac
      361 atgacttgaa cacgcgaccc tctgattaca aatcagatgc tctaccaact gagctaagcc
      421 ggctaatctt ttatgcgggt taagggactt gaacccccac gccgttaagc gccagatcct
      481 aaatctggtg cgtctgccaa ttccgccaaa cccgctttta tgacccgtac tgggctcgaa
      541 ccagtgaccc attgattaaa agtcaattgc tctaccaact gagctaacga gtctttcctt
      601 caaaaaatat gactactctt tgaacggtcc cgacgggaat cgaacccgcg atcttcgccg
      661 tgacagggcg acgtgataac cgctacacta cgggacctgt attttccaat ac
//
LOCUS       DAXMQE010000100          711 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.100, whole genome shotgun sequence.
ACCESSION   DAXMQE010000100 DAXMQE010000000
VERSION     DAXMQE010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 711)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 711)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..711
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.100"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            <1..>711
                     /locus_tag="ACF4ZO_001943"
     CDS             <1..>711
                     /locus_tag="ACF4ZO_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail spike protein"
                     /protein_id="HFD5487428.1"
                     /translation="LSLYAQRRIQMVDLSSHFNDDKNKKEPTIEEIRKLAQKYLKDNN
                     VGAPKVSIEVDYIDLSQTLDYQDFRVMEEVELCDIVPLYYPKFGITTESEKVVEIVYD
                     VYTDSNHTIKLGTIGQSISKSLTGGVSERINALENNQKVITNNQKQFELNLPKYLNDI
                     NGKRVWYEKPDDNIEHKIGDYWFEKNGKYQRTWIWDGHQWVKVLDTEDLNPNQRAFDE
                     AMAEIEKAKKAQEEINQRT"
BASE COUNT          259 a          128 c          145 g          179 t
ORIGIN      
        1 ctcagcttat atgctcagcg cagaatccaa atggttgatt tatcaagtca ttttaacgat
       61 gacaaaaata aaaaagagcc aacgatcgaa gaaatccgaa agctggctca gaaatacctt
      121 aaggataata acgttggtgc accaaaagtc agcattgagg ttgattatat tgacttgtca
      181 caaacgcttg actatcaaga ttttagagtc atggaagagg ttgagctttg cgacattgta
      241 ccactttatt atccaaagtt tggcatcaca actgagtctg aaaaagtcgt tgagattgtc
      301 tatgacgtct atacagatag caatcacaca atcaaattag gtacgattgg tcaatcaatc
      361 tctaaaagtt tgactggtgg tgtttctgaa cgtattaatg cgttggaaaa taatcaaaag
      421 gtaattacta acaaccaaaa acaatttgaa ctcaatctgc ctaaatacct caatgacatc
      481 aatggtaaac gcgtttggta cgaaaaacca gatgacaata ttgagcacaa gataggtgat
      541 tactggttcg aaaaaaatgg taagtatcag cgcacttgga tttgggatgg ccatcaatgg
      601 gtcaaggtac tagatacaga ggatttaaac cctaaccaac gggcctttga cgaggcaatg
      661 gctgaaatcg aaaaagccaa aaaagcgcaa gaagaaatca accagcgcac t
//
LOCUS       DAXMQE010000101          512 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.101, whole genome shotgun sequence.
ACCESSION   DAXMQE010000101 DAXMQE010000000
VERSION     DAXMQE010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 512)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 512)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..512
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.101"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            161..445
                     /locus_tag="ACF4ZO_001944"
     CDS             161..445
                     /locus_tag="ACF4ZO_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3310 domain-containing protein"
                     /protein_id="HFD5487429.1"
                     /translation="MLTEDTFKKIEELEAACQDTTDNIKKPSHYQGRHGMEAIDVVKN
                     FSACPEHEEGFYWGNAVKYLLRYHAKNGIEDLKKARQNLDWLIEKLEEVE"
BASE COUNT          184 a           71 c          123 g          134 t
ORIGIN      
        1 tgttaatagc tcacggatgc aaaataaaga tgtctgatga ggttttagca gacaagatag
       61 gtatttatac ttggcaatta aaagcgctct tagaacgcag aatattgcca aatgagagcg
      121 tgtgtaaatt gattataaat tttttgagag aggtggagag atgctgacgg aagatacgtt
      181 taaaaaaatt gaggagcttg aagctgcttg tcaggatacg acagataaca ttaaaaaacc
      241 atcacactat caaggcaggc atggcatgga agcaatcgat gtggttaaaa acttttcagc
      301 ttgtccagag cacgaggaag gtttttactg gggcaatgct gttaagtatt tactacgata
      361 tcatgctaaa aatggcattg aagacctcaa aaaagcaagg cagaaccttg attggttaat
      421 cgaaaagttg gaggaagtgg aatgataccg aaatttagag cgtttaacca aaagacccaa
      481 aaaatgtatg gtgttgatgg ctttaaatca ag
//
LOCUS       DAXMQE010000102          489 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.102, whole genome shotgun sequence.
ACCESSION   DAXMQE010000102 DAXMQE010000000
VERSION     DAXMQE010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 489)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 489)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..489
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.102"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            <1..>489
                     /locus_tag="ACF4ZO_001945"
     CDS             <1..>489
                     /locus_tag="ACF4ZO_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="gp58-like family protein"
                     /protein_id="HFD5487430.1"
                     /translation="QATSYVAPVVVEGSGESTGVFKSLEEMLSGLQSINLELTDTKNS
                     KLWSKIKLTNRGMLQEYYDGTIKTEIINSAKGIATRISEETGQKLALINDTIDGIRRE
                     YQDADRRLSASYQAGIEGLKATMRDDKLDLQAEIQASAHGLSQKYDDKLKQLSAKITT
                     TS"
BASE COUNT          151 a           91 c          120 g          127 t
ORIGIN      
        1 tcaagccact agctatgtgg cgcctgtggt tgttgagggt agcggtgagt cgacaggtgt
       61 gtttaaaagt cttgaggaga tgcttagtgg tctacagtct attaatttag agctgacaga
      121 tactaaaaac tccaaacttt ggtcaaaaat caagctgact aaccgtggca tgttgcagga
      181 gtactacgat ggtacgatta agactgagat tattaactcc gccaaaggta tcgctacacg
      241 cattagtgag gagactggtc aaaagctagc gctcatcaat gacaccattg atggtatcag
      301 acgtgagtat caagatgctg ataggcgctt atccgcaagt tatcaagctg gtattgaggg
      361 cttaaaagcc accatgcgtg atgataagtt agatttgcaa gctgagatac aagcaagtgc
      421 tcatggcttg tctcaaaagt atgatgataa gcttaagcag ctatcagcta aaatcacaac
      481 aacatctag
//
LOCUS       DAXMQE010000103          466 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.103, whole genome shotgun sequence.
ACCESSION   DAXMQE010000103 DAXMQE010000000
VERSION     DAXMQE010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 466)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.103"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            complement(50..220)
                     /locus_tag="ACF4ZO_001946"
     CDS             complement(50..220)
                     /locus_tag="ACF4ZO_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5487431.1"
                     /translation="MRKYIEFKDEWKSAADHLNDFIDKNKYAKVTVVGYQVVQLSPYG
                     RDLTYILAEVEE"
     gene            complement(217..>466)
                     /locus_tag="ACF4ZO_001947"
     CDS             complement(217..>466)
                     /locus_tag="ACF4ZO_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="YopX family protein"
                     /protein_id="HFD5487432.1"
                     /translation="LDDYILRQSTGLFDKNGVEIFEGDVVEYDDGEYLFAGKVVKTVF
                     GIYVKSYSFFSFEDFSDENTMTADVEIIGNIYEESVEE"
BASE COUNT          134 a          105 c           62 g          165 t
ORIGIN      
        1 attattttat taaagttatc acgtaaattt tgcaacgctt catctatcgt cattcttcca
       61 cctctgccaa aatataagtc aaatctcttc cgtaaggaga aagttgtacg acttgataac
      121 caacaactgt cacttttgcg tacttgtttt tgtcgataaa atcgttcagg tggtctgctg
      181 cacttttcca ttcgtcctta aattcaatat attttctcat tcttccacgc tttcttcgta
      241 aatgttgccg atgatttcaa cgtctgcggt cattgtattt tcgtccgaaa aatcttcaaa
      301 cgagaaaaaa ctgtaagatt ttacatatat tccaaatact gttttaacta cttttccagc
      361 gaacaaatat tctccgtcgt catattcgac cacatctccc tcaaaaatct caacaccgtt
      421 tttatcaaat agccctgtgg attgcctgag aatataatca tcaagg
//
LOCUS       DAXMQE010000104          440 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.104, whole genome shotgun sequence.
ACCESSION   DAXMQE010000104 DAXMQE010000000
VERSION     DAXMQE010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 440)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.104"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            <1..>440
                     /locus_tag="ACF4ZO_001948"
     CDS             <1..>440
                     /locus_tag="ACF4ZO_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFD5487433.1"
                     /translation="FVNGASVGAESALEIWKENLVGDDTFDVKSDILTLGSFNWEIDK
                     IGNARGALGGVAGSILDVYGGEYEFDNRTIILRKQMGRKAPTVLEYGRNIVSVEEERL
                     LDGNYTSIYPYVRYTPQPKPQEEAPGKPHVGEHKQPEEQLVTLP"
BASE COUNT          129 a           92 c          114 g          105 t
ORIGIN      
        1 tttgtaaacg gtgcgagcgt aggagccgaa tcagctttag aaatctggaa agaaaacctt
       61 gttggtgatg atacttttga cgttaaaagc gacatcttaa cgcttggtag ctttaactgg
      121 gaaattgata aaatcggcaa tgcccgtggt gctctaggag gtgtcgctgg ctctatccta
      181 gatgtttacg gtggtgagta cgagtttgac aaccgtacaa tcatcttacg caagcaaatg
      241 gggcgtaaag ctcccacggt attggagtat ggccgtaata tcgtcagcgt agaggaggag
      301 cgattgctag atggcaatta cacctctatc tatccttacg taagatatac gccacaacca
      361 aaaccgcaag aggaagcccc tggtaagccg catgtaggcg agcataaaca acccgaagaa
      421 cagctagtga cattgcctga
//
LOCUS       DAXMQE010000105          427 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.105, whole genome shotgun sequence.
ACCESSION   DAXMQE010000105 DAXMQE010000000
VERSION     DAXMQE010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 427)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.105"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            <1..>427
                     /locus_tag="ACF4ZO_001949"
     CDS             <1..>427
                     /locus_tag="ACF4ZO_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="gp58-like family protein"
                     /protein_id="HFD5487434.1"
                     /translation="YDNKLHQLSAKIKTTSSGTTEAYENKLAGLRAEFTRSNQGTRTE
                     LESQISGLRAVQQTTASQISQEIRDRTGAVSRVQQDLESYQRRLQDAEDNYSSLTHTV
                     RGLQSDVGSPTGKIQSRFTQLQYQIDQRVTRDGVMSIINQ"
BASE COUNT          138 a           94 c          105 g           90 t
ORIGIN      
        1 gtatgataat aagttacatc agttgtctgc taagattaaa acaacctcat caggcacgac
       61 cgaggcctac gagaataaac ttgcgggctt acgtgctgag tttactcgct caaatcaagg
      121 cacgaggaca gagctcgagt cacaaattag cggactaaga gcggtacaac agacaaccgc
      181 tagccaaatc tcacaagaga ttagagacag gacaggagca gtcagtcgtg tgcagcaaga
      241 cctagagagt tatcagcgtc gtttgcagga tgcggaagat aattacagta gcttaaccca
      301 tacagttaga ggtttgcaga gtgatgtggg atccccgact ggtaaaatcc aatcacgctt
      361 tacgcagctg caataccaaa tagaccagcg agtgactcgt gacggagtta tgtcaatcat
      421 taaccag
//
LOCUS       DAXMQE010000106          366 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.106, whole genome shotgun sequence.
ACCESSION   DAXMQE010000106 DAXMQE010000000
VERSION     DAXMQE010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 366)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 366)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..366
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.106"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            complement(<1..>366)
                     /locus_tag="ACF4ZO_001950"
     CDS             complement(<1..>366)
                     /locus_tag="ACF4ZO_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="PstC family ABC transporter permease"
                     /protein_id="HFD5487435.1"
                     /translation="TTDSLRAVPRHYREASMAMGATRWQTIWRVVLNAARPGIFTAVI
                     FGMARAFGEALAIQMVVGNSAVMPESLTTPAATLTSVLTMGIGNTVMGTVQNNVLWSL
                     ALVLLLMSLAFNSLVKLIT"
BASE COUNT          109 a           86 c           87 g           84 t
ORIGIN      
        1 tcgtgattaa tttgacaagg gaattgaagg ccagactcat taataataag actagggcaa
       61 gggaccaaag cacattattt tggaccgttc ccataacggt attaccgata cccattgtca
      121 agacagaagt tagggtagct gctggagttg tgagagactc tggcataact gcagagttac
      181 cgactaccat ttggatagcc aaggcttctc caaaagctct cgccattcca aaaataacag
      241 cggtaaaaat tcctggacga gctgcattaa ggacaacacg ccaaatggtt tgccaacggg
      301 ttgctcccat agccatagac gcttcgcggt aatgacgagg caccgcccgc agactgtctg
      361 ttgtca
//
LOCUS       DAXMQE010000107          334 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.107, whole genome shotgun sequence.
ACCESSION   DAXMQE010000107 DAXMQE010000000
VERSION     DAXMQE010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 334)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 334)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..334
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.107"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            <1..>334
                     /locus_tag="ACF4ZO_001951"
     CDS             <1..>334
                     /locus_tag="ACF4ZO_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="gp58-like family protein"
                     /protein_id="HFD5487436.1"
                     /translation="AEFTRSNQGMRTELESKISGLQSTQQATASQISQEIRDREGAVS
                     RVQQSLESYQRRMQDAEENYSSLTHTVRGLQSDVGSPTGKIQSRLTQLAGQIEQRVTR
                     DGVMSIISG"
BASE COUNT          100 a           66 c           93 g           75 t
ORIGIN      
        1 tgctgagttt actcgctcaa atcaaggcat gcggacagag ctggagtcta aaattagtgg
       61 gttgcaatca acgcaacaag caactgctag ccaaatctct caagagatta gagaccgtga
      121 aggtgctgtc agtcgtgtgc agcagagttt ggagagttac caaaggcgga tgcaggacgc
      181 agaagaaaac tatagtagct tgacccatac ggttagaggg ctacagagtg acgttggatc
      241 tccgactggt aaaatccaat cgcgccttac tcaactagca ggacaaattg agcagcgggt
      301 tactagagat ggtgtcatga gtattattag tggc
//
LOCUS       DAXMQE010000108          313 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.108, whole genome shotgun sequence.
ACCESSION   DAXMQE010000108 DAXMQE010000000
VERSION     DAXMQE010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 313)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 313)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..313
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.108"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            <1..>313
                     /locus_tag="ACF4ZO_001952"
     CDS             <1..>313
                     /locus_tag="ACF4ZO_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hyaluronoglucosaminidase"
                     /protein_id="HFD5487437.1"
                     /translation="QNKPNLDAFARKQETDSKITELKSNKADKNAVYLKAESNAKLDE
                     KLSLTGGIVTGQLQFKPNSGIKPSSSVGGAINIDMSKSEGAAMVMYTNKDTTDGPLMI
                     LR"
BASE COUNT          124 a           51 c           61 g           77 t
ORIGIN      
        1 tccaaaataa accaaatcta gatgcgtttg cacgaaaaca agaaactgat agtaaaatca
       61 ccgaattaaa atcaaataaa gcagataaaa acgctgttta cttaaaagca gagtcaaatg
      121 caaagctaga cgaaaaattg agtttgacag gcggcatagt gacaggacaa ctacagttta
      181 aacctaatag tggtattaaa ccctcatctt ccgtaggagg agcgattaac attgatatgt
      241 ctaaatcgga aggtgctgct atggtgatgt atacaaataa agatactact gatggaccat
      301 tgatgatttt acg
//
LOCUS       DAXMQE010000109          312 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.109, whole genome shotgun sequence.
ACCESSION   DAXMQE010000109 DAXMQE010000000
VERSION     DAXMQE010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 312)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 312)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..312
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.109"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            <1..295
                     /locus_tag="ACF4ZO_001953"
     CDS             <1..295
                     /locus_tag="ACF4ZO_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HFD5487438.1"
                     /translation="TIIDTIYEKRINHVPELMRMGADISVIGGQIVYQGPSRLTGAQV
                     KATDLRAGAALVIAGLMAEGKTEITNIEFILRGYASIIAKLTALGADIQLIED"
BASE COUNT           95 a           58 c           75 g           84 t
ORIGIN      
        1 aacgattatt gacactatat atgaaaagcg cattaaccat gtgccagagt tgatgcgcat
       61 gggagcagat atctcagtta ttggtggtca gattgtttat caagggccgt ctcgcctgac
      121 aggagctcag gtcaaagcca ctgatttacg tgccggagcg gctctagtga ttgctggtct
      181 aatggctgaa ggcaagacag aaattactaa tattgaattt atcttacgtg gctatgctag
      241 tatcattgca aaattaacag cactaggggc agatattcaa ttaatcgaag actaaagaga
      301 agctaacgct tc
//
LOCUS       DAXMQE010000110          308 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.110, whole genome shotgun sequence.
ACCESSION   DAXMQE010000110 DAXMQE010000000
VERSION     DAXMQE010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 308)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 308)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..308
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.110"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            <1..219
                     /locus_tag="ACF4ZO_001954"
     CDS             <1..219
                     /locus_tag="ACF4ZO_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001871253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFD5487439.1"
                     /translation="DNGSEFSLLSDLEAVDVYFAHPYSSHERGTNENFNGLLREYVPK
                     GVSLNPLTSEELDNDITAINERPRRLLQ"
BASE COUNT           92 a           76 c           51 g           89 t
ORIGIN      
        1 gataatggtt ctgagtttag tttactctca gacttagaag ctgttgacgt ttactttgca
       61 catccctatt cttcacatga gagaggaaca aacgagaact tcaatggcct cctcagagaa
      121 tatgtcccta aaggagtctc acttaatcca ctaacctctg aagaacttga caatgacatt
      181 actgccatca atgagcgccc aagacgactt cttcaatagc aatcctcaaa attcctgttt
      241 gagctatccc gaacaactta acctctggaa ctctagttat ctatgaactc gttgcacttg
      301 acttgaca
//
LOCUS       DAXMQE010000111          296 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.111, whole genome shotgun sequence.
ACCESSION   DAXMQE010000111 DAXMQE010000000
VERSION     DAXMQE010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 296)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 296)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..296
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.111"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            <1..>296
                     /locus_tag="ACF4ZO_001955"
     CDS             <1..>296
                     /locus_tag="ACF4ZO_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gp58-like family protein"
                     /protein_id="HFD5487440.1"
                     /translation="DKPTNYVAPVVVEGTGNPTGLFKDLKELNLELTDTANSQLWAKI
                     KLNNHGMLQTYFDTTIKNEILTTAQGIRETISDTERGLKSEFLRTVQGQRIQLK"
BASE COUNT           98 a           57 c           69 g           72 t
ORIGIN      
        1 gataagccaa ctaattacgt ggcgcccgtg gtagttgagg ggacaggtaa tccgactgga
       61 ttatttaaag acctcaagga gcttaactta gagctgacag acaccgctaa ttcccagctc
      121 tgggcaaaaa tcaagttaaa caatcatggt atgttacaga catactttga tacgactatt
      181 aaaaatgaga ttttaacaac ggctcaaggt atcagagaga ctatatctga tactgagcga
      241 ggacttaagt ccgagtttct aaggacagtg caaggtcagc gtatccagct taagag
//
LOCUS       DAXMQE010000112          251 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.112, whole genome shotgun sequence.
ACCESSION   DAXMQE010000112 DAXMQE010000000
VERSION     DAXMQE010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 251)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 251)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..251
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.112"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            <1..>251
                     /locus_tag="ACF4ZO_001956"
     CDS             <1..>251
                     /locus_tag="ACF4ZO_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD5487441.1"
                     /translation="LLPKNKIKVNNLEKLTEKEKEEIKNKIKDLNKNNFPKNTQVEVD
                     EKGNVSVTYPDKSKDMIESAKLVFQESKGAATEIEKPEM"
BASE COUNT          138 a           28 c           34 g           51 t
ORIGIN      
        1 cactacttcc aaaaaataaa ataaaagtta ataatttaga aaaattaaca gaaaaagaaa
       61 aagaggaaat caaaaataaa ataaaagact taaacaaaaa taatttccca aaaaatacac
      121 aagtagaagt agatgaaaaa ggaaatgtaa gtgtaacata tccagataaa tcaaaggata
      181 tgattgaatc agcaaaatta gttttccaag aatcaaaagg tgctgcaaca gaaattgaaa
      241 aaccagaaat g
//
LOCUS       DAXMQE010000113          228 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate 277
            SAMN39580989-rid20795033.denovo.113, whole genome shotgun sequence.
ACCESSION   DAXMQE010000113 DAXMQE010000000
VERSION     DAXMQE010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN39580989
            Sequence Read Archive: SRR27702947
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 228)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 228)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 24-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002063081.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002063081.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 19:02:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 1,957
            CDSs (total)                      :: 1,912
            Genes (coding)                    :: 1,854
            CDSs (with protein)               :: 1,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 31 of 58
            Pseudo Genes (incomplete)         :: 27 of 58
            Pseudo Genes (internal stop)      :: 18 of 58
            Pseudo Genes (multiple problems)  :: 14 of 58
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..228
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN39580989-rid20795033.denovo.113"
                     /isolate="277"
                     /isolation_source="sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /geo_loc_name="USA"
                     /collection_date="2021"
     gene            <1..>228
                     /locus_tag="ACF4ZO_001957"
     CDS             <1..>228
                     /locus_tag="ACF4ZO_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gp58-like family protein"
                     /protein_id="HFD5487442.1"
                     /translation="QLGLTVDGLKLDLNKANEQTASLQASINGLRQEYQDAERKLSAS
                     YQTGINGLKATMANDKYDLKAEIQATARGLSQ"
BASE COUNT           86 a           48 c           48 g           46 t
ORIGIN      
        1 caactcggct tgacggtcga tggtctaaaa cttgatttaa acaaagcaaa cgaacagaca
       61 gctagtttac aggctagtat caatggtttg cgacaagaat atcaagacgc tgaaaggaag
      121 ttatccgcaa gctatcagac tggcattaac ggcctaaaag caacaatggc caatgataaa
      181 tacgacctaa aagctgagat acaagcaacc gctcgaggat tatcacaa
//
